# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Copine PF07002.11 EKE36869.1 - 1.1e-40 138.7 0.0 1.7e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EKE36869.1 - 6.8e-13 48.8 0.0 9.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EKE36869.1 - 0.00058 20.0 0.0 0.00076 19.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE36869.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VPS9 PF02204.13 EKE36870.1 - 2.6e-11 43.4 0.8 2.6e-11 43.4 0.6 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF4302 PF14135.1 EKE36870.1 - 0.0071 15.7 0.4 0.013 14.9 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4302) CTP_transf_1 PF01148.15 EKE36871.1 - 4.2e-10 39.7 16.0 6.3e-10 39.1 11.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DKNYY PF13644.1 EKE36872.1 - 0.0083 16.4 0.9 0.0097 16.1 0.6 1.1 1 0 0 1 1 1 1 DKNYY family Med14 PF08638.6 EKE36873.1 - 0.016 14.4 0.1 0.041 13.1 0.1 1.7 1 1 0 1 1 1 0 Mediator complex subunit MED14 RPW8 PF05659.6 EKE36873.1 - 3 7.3 7.3 14 5.2 2.3 2.8 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WD40 PF00400.27 EKE36874.1 - 1.8e-08 33.9 0.0 0.00019 21.2 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Metallophos PF00149.23 EKE36876.1 - 2.9e-06 26.8 0.2 5.8e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NfrA_C PF13283.1 EKE36876.1 - 0.027 13.8 0.3 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term Pkinase PF00069.20 EKE36877.1 - 6.4e-64 215.5 6.4 3.5e-54 183.6 0.8 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EKE36877.1 - 1.3e-35 122.7 4.3 5.5e-32 110.8 0.4 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase RIO1 PF01163.17 EKE36877.1 - 0.0037 16.6 0.0 0.01 15.1 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EKE36877.1 - 0.015 14.2 0.0 0.042 12.7 0.0 1.8 1 0 0 1 1 1 0 Kinase-like Sulfotransfer_3 PF13469.1 EKE36878.1 - 7.8e-08 33.3 0.0 1.3e-07 32.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE36878.1 - 2.8e-07 30.0 0.2 1.3e-06 27.8 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 EKE36879.1 - 0.0049 16.4 1.2 0.01 15.3 0.8 1.5 1 0 0 1 1 1 1 Stf0 sulphotransferase EF-hand_8 PF13833.1 EKE36879.1 - 0.068 12.7 0.1 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair HAUS6_N PF14661.1 EKE36879.1 - 0.92 8.8 26.6 2.3 7.5 6.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DENN PF02141.16 EKE36881.1 - 9.5e-14 51.5 4.9 1.8e-13 50.6 3.4 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Pkinase PF00069.20 EKE36883.1 - 2.6e-32 111.9 0.5 5e-32 111.0 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE36883.1 - 4.7e-29 101.2 0.2 8.6e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.8 EKE36883.1 - 4.4e-05 22.2 66.5 0.00028 19.6 30.5 14.2 1 1 12 13 13 13 7 Giardia variant-specific surface protein Kdo PF06293.9 EKE36883.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EKE36884.1 - 2.5e-15 56.2 0.0 3e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE36884.1 - 5.4e-13 48.6 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Myotub-related PF06602.9 EKE36885.1 - 5.5e-106 354.3 0.1 9.8e-106 353.4 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain TAP42 PF04177.7 EKE36885.1 - 0.00058 18.9 3.7 0.00061 18.8 1.3 1.8 1 1 1 2 2 2 1 TAP42-like family Y_phosphatase3 PF13350.1 EKE36885.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family ComC PF03047.9 EKE36885.1 - 0.083 12.3 0.5 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 COMC family LRR_5 PF13306.1 EKE36887.1 - 1.5e-39 134.6 14.6 1e-24 86.6 3.4 2.4 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE36887.1 - 3.5e-11 42.6 0.1 0.00081 19.0 0.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat RhoGEF PF00621.15 EKE36888.1 - 7.2e-20 71.6 6.5 1.1e-19 71.0 4.5 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF1632 PF07857.7 EKE36889.1 - 3e-60 203.6 6.3 3e-45 154.4 3.0 2.4 1 1 1 2 2 2 2 CEO family (DUF1632) Sugar_transport PF06800.7 EKE36889.1 - 2.9e-09 36.4 16.9 1.7e-05 24.0 5.0 2.4 2 0 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.6 EKE36889.1 - 0.0024 16.5 0.0 0.0067 15.1 0.0 1.8 1 0 0 1 1 1 1 Ureide permease FAM176 PF14851.1 EKE36889.1 - 0.0088 15.7 0.5 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 FAM176 family DUF1510 PF07423.6 EKE36889.1 - 0.014 14.7 6.0 0.021 14.1 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ly49 PF08391.5 EKE36889.1 - 0.67 10.0 3.5 1.4 9.1 2.4 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4231 PF14015.1 EKE36889.1 - 9.2 6.2 7.7 27 4.7 0.7 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DUF3534 PF12053.3 EKE36890.1 - 0.11 12.3 4.1 0.1 12.4 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3534) Ribosomal_S14 PF00253.16 EKE36890.1 - 0.2 11.0 1.7 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DNA_primase_S PF01896.14 EKE36891.1 - 2.1e-22 79.5 1.1 3e-22 79.0 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit FMO-like PF00743.14 EKE36891.1 - 0.023 12.8 0.8 0.041 12.0 0.5 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like ACC_central PF08326.7 EKE36891.1 - 0.038 12.1 1.3 0.054 11.6 0.9 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DNA_primase_S PF01896.14 EKE36892.1 - 2.4e-13 50.1 0.2 3.3e-13 49.6 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit TLD PF07534.11 EKE36893.1 - 9.2e-07 28.9 2.9 3.4e-06 27.0 2.0 1.9 1 1 0 1 1 1 1 TLD SNAPc_SNAP43 PF09808.4 EKE36894.1 - 6.7e-17 61.8 2.7 6.7e-17 61.8 1.9 1.5 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Pneumo_M2 PF07380.6 EKE36894.1 - 2.1 8.3 5.6 8 6.5 0.2 2.7 3 0 0 3 3 3 0 Pneumovirus M2 protein Clathrin_propel PF01394.15 EKE36895.1 - 0.01 16.1 0.7 0.33 11.3 0.2 3.2 2 0 0 2 2 2 1 Clathrin propeller repeat G-patch PF01585.18 EKE36896.1 - 3.3e-08 33.1 0.9 7.4e-08 32.0 0.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EKE36896.1 - 0.032 14.0 1.1 0.032 14.0 0.7 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site PGG PF13962.1 EKE36898.1 - 0.59 9.7 12.5 0.66 9.6 0.5 4.0 3 2 1 4 4 4 0 Domain of unknown function Peptidase_M24 PF00557.19 EKE36899.1 - 1.1e-49 168.9 0.0 1.4e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EKE36899.1 - 2.8e-25 88.2 0.0 2.6e-24 85.1 0.0 2.3 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain RRM_1 PF00076.17 EKE36900.1 - 1.1e-25 89.0 0.2 1.4e-25 88.6 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE36900.1 - 1.7e-17 63.1 0.0 2.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE36900.1 - 1.5e-12 47.1 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKE36900.1 - 0.00031 20.5 0.1 0.00053 19.8 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 EKE36900.1 - 0.04 13.6 0.2 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 Limkain b1 OB_RNB PF08206.6 EKE36900.1 - 0.062 12.8 1.4 0.17 11.4 1.0 1.8 1 1 0 1 1 1 0 Ribonuclease B OB domain DUF4140 PF13600.1 EKE36900.1 - 0.099 13.1 0.3 0.29 11.5 0.0 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rap_GAP PF02145.10 EKE36901.1 - 3.3e-22 78.7 0.1 1e-21 77.2 0.1 1.9 1 0 0 1 1 1 1 Rap/ran-GAP RBD PF02196.10 EKE36901.1 - 0.051 13.3 0.1 0.45 10.2 0.0 2.5 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF605 PF04652.11 EKE36902.1 - 7e-15 55.3 17.0 1.8e-09 37.4 8.6 2.1 1 1 1 2 2 2 2 Vta1 like EF-hand_1 PF00036.27 EKE36904.1 - 7.6e-28 93.6 5.8 7.4e-06 24.8 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKE36904.1 - 6.5e-26 90.2 1.7 2.7e-12 46.6 0.1 2.5 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EKE36904.1 - 6.7e-26 88.4 6.4 3.4e-06 26.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EKE36904.1 - 2.1e-24 83.1 3.2 5.2e-05 22.7 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EKE36904.1 - 1e-22 79.4 6.9 3.9e-08 32.7 1.1 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKE36904.1 - 1.3e-08 34.8 0.0 0.00028 20.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EKE36904.1 - 9e-06 25.2 0.6 0.78 9.4 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EKE36904.1 - 1.8e-05 24.4 1.8 0.069 12.8 0.0 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Cro PF09048.5 EKE36904.1 - 0.012 15.2 0.1 0.27 10.8 0.0 2.7 3 0 0 3 3 3 0 Cro EF-hand_9 PF14658.1 EKE36904.1 - 0.017 15.0 0.1 0.092 12.6 0.0 2.1 3 0 0 3 3 3 0 EF-hand domain Bse634I PF07832.6 EKE36904.1 - 0.058 12.5 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease DUF1707 PF08044.6 EKE36904.1 - 0.12 12.1 0.1 27 4.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) Dockerin_1 PF00404.13 EKE36904.1 - 7.1 6.5 16.0 16 5.4 0.2 4.2 4 0 0 4 4 4 0 Dockerin type I repeat Nup54 PF13874.1 EKE36905.1 - 0.00067 19.3 1.5 0.00067 19.3 1.1 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 TACC PF05010.9 EKE36905.1 - 0.0054 16.5 3.5 0.0071 16.1 2.4 1.4 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) COG5 PF10392.4 EKE36905.1 - 0.025 14.5 6.6 0.057 13.3 0.4 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DASH_Dad3 PF08656.5 EKE36905.1 - 0.045 13.4 3.3 0.056 13.1 0.0 2.7 2 1 1 3 3 3 0 DASH complex subunit Dad3 Pex24p PF06398.6 EKE36905.1 - 0.077 11.7 1.6 0.95 8.1 0.3 2.1 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Urm1 PF09138.6 EKE36905.1 - 0.11 12.6 1.1 0.27 11.3 0.5 1.8 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) RRP7 PF12923.2 EKE36905.1 - 0.24 11.4 4.8 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) P4Ha_N PF08336.6 EKE36905.1 - 0.57 10.0 9.4 0.39 10.5 1.5 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spore_III_AB PF09548.5 EKE36905.1 - 0.6 9.8 6.6 0.087 12.5 0.7 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) SlyX PF04102.7 EKE36905.1 - 3.4 8.1 8.6 4.5 7.7 2.2 2.6 2 0 0 2 2 2 0 SlyX Cas_Cas6 PF01881.11 EKE36905.1 - 6.5 6.9 9.0 1.9 8.7 0.5 3.2 3 1 0 3 3 3 0 CRISPR associated protein Cas6 LRR_5 PF13306.1 EKE36906.1 - 2e-51 173.0 27.5 6.9e-34 116.3 7.0 2.4 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE36906.1 - 1.1e-23 82.7 16.1 2.3e-07 30.4 0.2 5.3 1 1 4 5 5 5 5 Leucine rich repeat PBD PF00786.23 EKE36907.1 - 0.00021 21.6 0.0 0.00021 21.6 0.0 5.2 7 1 0 7 7 7 1 P21-Rho-binding domain CD20 PF04103.10 EKE36908.1 - 0.03 14.2 2.6 2.8 7.8 0.5 2.5 2 0 0 2 2 2 0 CD20-like family Rep_fac_C PF08542.6 EKE36908.1 - 0.069 13.1 0.2 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain RabGAP-TBC PF00566.13 EKE36909.1 - 1.4e-33 116.2 0.5 2.2e-33 115.5 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cation_efflux PF01545.16 EKE36909.1 - 0.018 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Cation efflux family Ras PF00071.17 EKE36910.1 - 2e-40 137.8 2.2 2.3e-40 137.6 1.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE36910.1 - 9.2e-16 58.4 0.2 1.7e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE36910.1 - 1.3e-14 53.7 0.5 1.6e-14 53.5 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE36910.1 - 1.2e-07 31.6 0.2 3.5e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE36910.1 - 8.8e-07 28.5 0.2 0.00012 21.5 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE36910.1 - 2.1e-06 27.0 0.4 2.4e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE36910.1 - 4.2e-06 26.0 0.1 5.7e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EKE36910.1 - 0.00059 19.6 0.3 0.0087 15.8 0.0 2.2 1 1 1 2 2 2 1 Dynamin family MobB PF03205.9 EKE36910.1 - 0.012 15.3 0.2 0.039 13.6 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EKE36910.1 - 0.012 14.7 0.1 0.024 13.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EKE36910.1 - 0.017 14.3 0.6 0.057 12.6 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EKE36910.1 - 0.018 14.5 0.0 0.024 14.0 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EKE36910.1 - 0.035 13.1 0.1 0.085 11.8 0.0 1.7 2 0 0 2 2 2 0 Septin AAA PF00004.24 EKE36910.1 - 0.072 13.2 0.1 0.34 11.1 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 EKE36911.1 - 0.022 13.5 0.1 0.022 13.5 0.1 1.8 1 1 1 2 2 2 0 SNF2 family N-terminal domain WD40 PF00400.27 EKE36912.1 - 3.1e-47 156.8 14.2 4.1e-09 35.9 0.0 9.5 9 0 0 9 9 9 8 WD domain, G-beta repeat Utp13 PF08625.6 EKE36912.1 - 2.3e-10 40.2 1.1 1.1e-09 38.0 0.7 2.1 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain PQQ_2 PF13360.1 EKE36912.1 - 5.1e-06 26.1 0.3 0.04 13.3 0.0 4.2 2 1 1 3 3 3 2 PQQ-like domain Nup160 PF11715.3 EKE36912.1 - 5.5e-06 24.8 6.0 0.055 11.5 0.0 4.7 2 2 2 5 5 5 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EKE36912.1 - 0.027 14.7 3.3 19 5.7 0.0 5.0 5 2 2 7 7 7 0 PQQ-like domain Sulfotransfer_3 PF13469.1 EKE36913.1 - 9.6e-07 29.8 0.0 2.2e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE36913.1 - 5e-06 25.9 0.0 1.1e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain CHASE2 PF05226.6 EKE36913.1 - 0.055 12.7 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 CHASE2 domain TSC22 PF01166.13 EKE36914.1 - 0.093 12.7 0.2 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Myosin_tail_1 PF01576.14 EKE36915.1 - 4.6e-15 54.4 303.7 0.00013 19.8 30.1 7.4 1 1 4 6 6 6 6 Myosin tail Reo_sigmaC PF04582.7 EKE36915.1 - 3e-11 43.0 100.5 0.00023 20.4 2.8 11.6 1 1 11 13 13 13 10 Reovirus sigma C capsid protein IncA PF04156.9 EKE36915.1 - 2.9e-09 36.8 270.7 0.071 12.7 14.8 13.6 1 1 13 14 14 12 5 IncA protein AAA_13 PF13166.1 EKE36915.1 - 6.3e-09 34.8 259.4 0.0024 16.4 17.3 9.8 1 1 9 11 11 11 9 AAA domain HALZ PF02183.13 EKE36915.1 - 0.00092 18.8 15.6 0.0013 18.3 3.5 18.7 21 2 1 22 22 22 2 Homeobox associated leucine zipper DUF3584 PF12128.3 EKE36915.1 - 0.00096 16.6 29.5 0.00096 16.6 20.4 6.9 1 1 6 7 7 7 4 Protein of unknown function (DUF3584) ADIP PF11559.3 EKE36915.1 - 0.0015 18.4 2.8 0.0015 18.4 1.9 16.9 1 1 16 18 18 17 8 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.6 EKE36915.1 - 0.0032 16.9 15.8 0.0032 16.9 11.0 18.6 1 1 19 20 20 13 3 Phage minor structural protein GP20 KLRAQ PF10205.4 EKE36915.1 - 0.0032 17.4 9.4 0.0032 17.4 6.5 15.4 2 2 15 18 18 11 2 Predicted coiled-coil domain-containing protein TPR_MLP1_2 PF07926.7 EKE36915.1 - 0.0046 16.6 24.0 0.0046 16.6 16.7 14.8 1 1 14 15 15 12 5 TPR/MLP1/MLP2-like protein DUF4164 PF13747.1 EKE36915.1 - 0.0048 16.9 0.6 0.0048 16.9 0.4 17.5 3 3 17 21 21 17 1 Domain of unknown function (DUF4164) Nup54 PF13874.1 EKE36915.1 - 0.0054 16.3 5.3 0.0054 16.3 3.7 14.2 3 3 10 15 15 12 2 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.4 EKE36915.1 - 0.15 11.8 291.3 0.035 13.9 20.2 14.6 2 2 14 16 16 15 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EKE36915.1 - 3.7 6.9 256.7 0.24 10.8 30.9 9.1 1 1 7 8 8 7 0 Intermediate filament protein Actin PF00022.14 EKE36916.1 - 1.6e-32 112.4 0.0 5.5e-30 104.0 0.0 2.5 1 1 0 1 1 1 1 Actin PAP2 PF01569.16 EKE36918.1 - 2.5e-20 72.4 6.4 3.2e-20 72.1 1.9 2.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EKE36918.1 - 3.6 7.9 16.9 0.049 13.8 1.9 3.1 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DUF159 PF02586.9 EKE36919.1 - 0.026 14.0 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised ACR, COG2135 DASH_Duo1 PF08651.5 EKE36919.1 - 2.5 7.7 7.6 2.4 7.8 0.1 3.6 4 0 0 4 4 4 0 DASH complex subunit Duo1 MCM PF00493.18 EKE36920.1 - 7.2e-125 416.1 0.3 5.7e-124 413.2 0.0 2.0 2 0 0 2 2 2 1 MCM2/3/5 family Mg_chelatase PF01078.16 EKE36920.1 - 1.1e-09 37.8 1.3 3.6e-06 26.3 0.0 2.9 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKE36920.1 - 4.2e-08 33.0 0.0 1.1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.1 EKE36920.1 - 3.7e-06 27.4 0.1 2.7e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.6 EKE36920.1 - 4.5e-06 26.2 0.0 1.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EKE36920.1 - 7.6e-06 26.1 0.4 0.00015 21.9 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EKE36920.1 - 0.0019 17.7 1.3 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EKE36920.1 - 0.0021 18.2 0.2 0.059 13.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EKE36920.1 - 0.0029 17.7 0.2 5.7 7.1 0.0 3.3 2 1 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EKE36920.1 - 0.0062 15.6 0.0 0.02 13.9 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EKE36920.1 - 0.011 15.2 0.9 0.051 13.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain HypA PF01155.14 EKE36920.1 - 0.011 15.3 0.8 0.032 13.9 0.5 1.8 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Sigma54_activat PF00158.21 EKE36920.1 - 0.021 14.2 0.0 0.15 11.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EKE36920.1 - 0.084 12.8 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EKE36920.1 - 0.2 11.9 1.8 1.2 9.4 0.0 2.8 3 1 0 3 3 3 0 ABC transporter T4_baseplate PF12322.3 EKE36920.1 - 5.8 6.1 9.5 7.9 5.6 0.5 3.4 3 1 0 3 3 3 0 T4 bacteriophage base plate protein Acetyltransf_7 PF13508.1 EKE36921.1 - 6.4e-11 42.2 0.2 1.2e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKE36921.1 - 1.9e-10 40.6 0.0 4.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKE36921.1 - 0.00098 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein TIP120 PF08623.5 EKE36922.1 - 5.3e-27 94.4 0.4 5.3e-27 94.4 0.3 4.9 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EKE36922.1 - 3.6e-13 48.3 0.4 0.023 14.7 0.0 7.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EKE36922.1 - 3.6e-08 33.6 0.6 0.19 12.2 0.0 5.6 6 1 1 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.1 EKE36922.1 - 4.4e-08 33.2 0.0 0.1 12.9 0.0 5.1 5 1 0 5 5 5 2 HEAT repeats Arm PF00514.18 EKE36922.1 - 0.003 17.3 0.2 13 5.7 0.0 4.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat TLD PF07534.11 EKE36923.1 - 0.00012 22.1 1.2 0.0008 19.4 0.7 1.9 1 1 1 2 2 2 2 TLD FAM72 PF14976.1 EKE36923.1 - 0.015 15.1 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 FAM72 protein Ribosomal_L22 PF00237.14 EKE36924.1 - 1.5e-32 111.6 0.3 2e-32 111.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ornatin PF02088.10 EKE36924.1 - 0.82 9.2 2.7 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Ornatin CTP_transf_1 PF01148.15 EKE36925.1 - 5.9e-38 131.0 21.6 7.6e-38 130.6 14.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S26e PF01283.14 EKE36926.1 - 1.3e-46 157.5 12.4 1.7e-46 157.1 8.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EKE36926.1 - 0.0021 18.3 1.5 0.16 12.4 0.5 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP19 PF01922.12 EKE36926.1 - 0.0092 16.5 2.2 0.021 15.4 1.5 1.8 1 1 0 1 1 1 1 SRP19 protein Mu-like_Com PF10122.4 EKE36926.1 - 0.0095 14.9 0.7 0.02 13.9 0.5 1.5 1 0 0 1 1 1 1 Mu-like prophage protein Com GFA PF04828.9 EKE36926.1 - 0.025 14.5 2.5 0.11 12.4 1.3 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Fer4_17 PF13534.1 EKE36926.1 - 0.16 12.3 3.6 0.16 12.3 1.4 1.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.22 EKE36926.1 - 0.18 11.4 5.0 1.1 9.0 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Herpes_UL49_1 PF03117.9 EKE36926.1 - 0.21 10.6 2.5 0.34 9.9 1.3 1.5 1 1 0 1 1 1 0 UL49 family zf-ribbon_3 PF13248.1 EKE36926.1 - 0.55 9.5 3.9 3.7 6.8 2.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Fer4_9 PF13187.1 EKE36926.1 - 0.56 10.5 4.5 0.74 10.1 1.9 2.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE36926.1 - 1.5 8.8 4.4 1.2 9.1 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 EKE36926.1 - 9.8 6.6 8.9 7.7 7.0 1.9 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain PRMT5 PF05185.11 EKE36927.1 - 2.5e-121 405.7 5.7 3.3e-121 405.3 3.9 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 EKE36927.1 - 0.00016 21.2 0.0 0.00041 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EKE36927.1 - 0.011 15.2 0.1 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein WH2 PF02205.15 EKE36928.1 - 6.7e-15 54.1 9.0 1.1e-08 34.3 0.7 3.2 3 0 0 3 3 3 3 WH2 motif Thymosin PF01290.15 EKE36928.1 - 0.045 13.3 5.8 0.56 9.8 0.5 2.4 1 1 1 2 2 2 0 Thymosin beta-4 family UCH PF00443.24 EKE36929.1 - 9.4e-25 87.2 9.4 9.4e-25 87.2 6.5 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Thoc2 PF11732.3 EKE36929.1 - 0.045 13.5 2.6 2.6 7.8 0.2 3.1 2 0 0 2 2 2 0 Transcription- and export-related complex subunit Pkinase PF00069.20 EKE36930.1 - 1.9e-50 171.4 0.0 6e-50 169.7 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE36930.1 - 7.3e-19 67.8 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE36930.1 - 0.00076 19.2 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4603 PF15376.1 EKE36930.1 - 0.005 14.1 0.2 0.005 14.1 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4603) RIO1 PF01163.17 EKE36930.1 - 0.0057 16.0 0.2 0.0057 16.0 0.1 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EKE36930.1 - 0.11 12.0 2.7 0.13 11.7 0.2 2.4 2 1 1 3 3 3 0 Choline/ethanolamine kinase Y_phosphatase PF00102.22 EKE36931.1 - 0.0021 17.4 0.0 0.0051 16.1 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EKE36931.1 - 0.026 14.7 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family IpgD PF05925.7 EKE36931.1 - 0.031 12.5 0.5 0.12 10.5 0.2 2.0 1 1 0 2 2 2 0 Enterobacterial virulence protein IpgD Med9 PF07544.8 EKE36932.1 - 0.0036 17.0 2.4 0.0053 16.4 1.7 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Phage_HK97_TLTM PF06120.6 EKE36932.1 - 0.0048 16.2 1.5 0.0056 16.0 1.1 1.0 1 0 0 1 1 1 1 Tail length tape measure protein YxiJ PF14176.1 EKE36932.1 - 0.01 15.9 0.4 0.012 15.7 0.2 1.2 1 0 0 1 1 1 0 YxiJ-like protein CorA PF01544.13 EKE36932.1 - 0.011 14.8 1.2 0.011 14.7 0.9 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FliD_C PF07195.7 EKE36932.1 - 0.014 14.7 4.5 0.017 14.4 3.1 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3450 PF11932.3 EKE36932.1 - 0.014 14.6 2.8 0.014 14.6 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.15 EKE36932.1 - 0.014 15.0 5.1 0.023 14.4 3.5 1.5 1 1 0 1 1 1 0 Prefoldin subunit ABC_tran_2 PF12848.2 EKE36932.1 - 0.015 15.1 0.7 0.02 14.7 0.5 1.2 1 0 0 1 1 1 0 ABC transporter IncA PF04156.9 EKE36932.1 - 0.016 14.8 3.7 0.026 14.1 2.6 1.4 1 1 0 1 1 1 0 IncA protein HR1 PF02185.11 EKE36932.1 - 0.017 14.8 5.2 0.022 14.4 3.6 1.2 1 0 0 1 1 1 0 Hr1 repeat Fib_alpha PF08702.5 EKE36932.1 - 0.026 14.6 3.1 0.031 14.4 2.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EKE36932.1 - 0.029 14.2 4.1 0.032 14.0 2.8 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EKE36932.1 - 0.029 14.1 7.9 0.061 13.1 5.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HSD3 PF15244.1 EKE36932.1 - 0.036 13.3 2.2 0.043 13.0 1.5 1.0 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase Mgr1 PF08602.5 EKE36932.1 - 0.051 12.5 4.6 0.061 12.3 3.2 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Phasin_2 PF09361.5 EKE36932.1 - 0.055 13.5 2.7 3.2 7.8 0.3 2.0 1 1 1 2 2 2 0 Phasin protein DUF4404 PF14357.1 EKE36932.1 - 0.056 13.8 1.5 0.068 13.5 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF328 PF03883.9 EKE36932.1 - 0.056 12.7 1.9 0.06 12.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF328) Laminin_II PF06009.7 EKE36932.1 - 0.057 13.1 3.0 0.067 12.9 2.0 1.1 1 0 0 1 1 1 0 Laminin Domain II Prefoldin PF02996.12 EKE36932.1 - 0.058 13.0 5.1 0.078 12.6 2.7 1.6 1 1 0 1 1 1 0 Prefoldin subunit TYW3 PF02676.9 EKE36932.1 - 0.064 12.3 0.6 0.072 12.2 0.4 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF1664 PF07889.7 EKE36932.1 - 0.067 12.9 2.1 0.078 12.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EKE36932.1 - 0.078 13.1 6.3 0.14 12.2 4.4 1.6 1 1 0 1 1 1 0 Syntaxin Med21 PF11221.3 EKE36932.1 - 0.087 12.7 2.6 0.1 12.5 1.8 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex EAP30 PF04157.11 EKE36932.1 - 0.087 11.9 1.7 0.099 11.7 1.2 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family AAA_10 PF12846.2 EKE36932.1 - 0.09 12.1 0.1 0.09 12.1 0.1 1.0 1 0 0 1 1 1 0 AAA-like domain PAS_8 PF13188.1 EKE36932.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 PAS domain YihI PF04220.7 EKE36932.1 - 0.16 11.2 4.6 0.18 11.1 3.2 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF730 PF05325.6 EKE36932.1 - 0.19 11.5 1.7 0.22 11.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF730) TBPIP PF07106.8 EKE36932.1 - 0.37 10.3 7.8 0.38 10.2 5.4 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EKE36932.1 - 0.41 9.0 4.0 0.43 8.9 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Adaptin_binding PF10199.4 EKE36932.1 - 0.54 10.5 4.1 0.59 10.4 2.8 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF16 PF01519.11 EKE36932.1 - 0.82 9.9 5.3 0.97 9.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 eIF-4B PF06273.6 EKE36932.1 - 0.95 8.1 2.9 1.1 7.9 2.0 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF2963 PF11178.3 EKE36932.1 - 0.99 8.8 0.1 0.99 8.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) YvrJ PF12841.2 EKE36932.1 - 2 7.7 3.8 14 5.0 0.0 2.7 3 1 0 3 3 3 0 YvrJ protein family RFC1 PF08519.7 EKE36933.1 - 9.2e-15 54.7 0.1 9.2e-15 54.7 0.1 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EKE36933.1 - 5.8e-14 52.0 0.5 6.4e-13 48.6 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 EKE36933.1 - 3.5e-12 45.7 1.0 6.8e-08 31.6 0.0 2.5 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EKE36933.1 - 7.5e-11 42.3 0.1 2.6e-10 40.6 0.1 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.2 EKE36933.1 - 4.2e-06 26.5 0.2 8.8e-05 22.2 0.0 2.7 2 0 0 2 2 2 1 twin BRCT domain RuvB_N PF05496.7 EKE36933.1 - 6.3e-06 25.4 0.0 2.5e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EKE36933.1 - 3.6e-05 23.6 0.0 0.00013 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE36933.1 - 0.00025 21.8 2.5 0.00037 21.2 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EKE36933.1 - 0.0012 19.1 0.1 0.0012 19.1 0.1 3.4 3 1 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EKE36933.1 - 0.0016 17.5 0.9 0.004 16.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EKE36933.1 - 0.019 15.1 0.4 0.15 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKE36933.1 - 0.021 14.7 0.1 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EKE36933.1 - 0.039 13.6 0.4 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EKE36933.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EKE36933.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain OGFr_N PF04664.8 EKE36934.1 - 8.4e-33 113.4 4.3 8.4e-33 113.4 3.0 1.7 2 0 0 2 2 2 1 Opioid growth factor receptor (OGFr) conserved region Ribosomal_S8e PF01201.17 EKE36934.1 - 0.48 10.5 10.1 0.15 12.2 4.3 2.0 1 1 1 2 2 2 0 Ribosomal protein S8e LRR_4 PF12799.2 EKE36935.1 - 8.7e-54 178.4 101.6 5.5e-07 29.0 1.1 14.1 7 4 7 15 15 15 14 Leucine Rich repeats (2 copies) PP2C PF00481.16 EKE36935.1 - 5.2e-45 153.8 0.0 7.4e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EKE36935.1 - 8.7e-44 147.1 95.2 2.3e-08 33.6 0.4 12.4 3 2 12 15 15 15 15 Leucine rich repeat LRR_1 PF00560.28 EKE36935.1 - 8.3e-28 92.1 100.5 0.061 13.3 0.1 22.1 20 4 3 23 23 23 14 Leucine Rich Repeat LRR_7 PF13504.1 EKE36935.1 - 4.4e-18 62.2 68.2 0.69 10.3 0.0 20.9 22 0 0 22 22 22 5 Leucine rich repeat LRR_6 PF13516.1 EKE36935.1 - 8.9e-08 31.4 94.4 1.4 9.1 0.3 18.7 16 2 3 19 19 19 9 Leucine Rich repeat PP2C_2 PF13672.1 EKE36935.1 - 0.00095 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2322 PF10084.4 EKE36935.1 - 0.083 12.6 0.0 8.6 6.1 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) Rap_GAP PF02145.10 EKE36936.1 - 1.2e-52 178.0 0.0 3.8e-52 176.4 0.0 1.9 1 0 0 1 1 1 1 Rap/ran-GAP DUF1632 PF07857.7 EKE36937.1 - 0.00046 19.5 0.2 0.00058 19.1 0.1 1.1 1 0 0 1 1 1 1 CEO family (DUF1632) COX2_TM PF02790.10 EKE36937.1 - 0.0043 16.9 0.4 0.0068 16.3 0.3 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DUF605 PF04652.11 EKE36937.1 - 3 7.1 14.3 3.1 7.1 9.9 1.0 1 0 0 1 1 1 0 Vta1 like ODV-E18 PF10717.4 EKE36937.1 - 4.1 6.9 7.2 7.1 6.1 0.5 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Totivirus_coat PF05518.6 EKE36937.1 - 6 4.5 8.8 6.8 4.3 6.1 1.0 1 0 0 1 1 1 0 Totivirus coat protein Sulfotransfer_3 PF13469.1 EKE36939.1 - 2e-06 28.7 0.0 5.9e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE36939.1 - 0.00011 21.6 1.0 0.0006 19.1 0.7 2.0 1 1 0 1 1 1 1 Sulfotransferase domain CheR_N PF03705.10 EKE36939.1 - 0.069 12.5 0.1 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain Rap_GAP PF02145.10 EKE36940.1 - 3e-46 157.1 1.1 1.4e-45 154.9 0.8 2.3 1 0 0 1 1 1 1 Rap/ran-GAP ABC_tran PF00005.22 EKE36941.1 - 3.5e-50 169.8 0.3 6.2e-31 107.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKE36941.1 - 3e-31 108.8 48.8 1.3e-18 67.4 12.2 2.9 3 0 0 3 3 2 2 ABC transporter transmembrane region T2SE PF00437.15 EKE36941.1 - 4.2e-08 32.4 0.1 0.00025 20.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 EKE36941.1 - 8.3e-08 31.7 9.0 0.1 11.8 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 EKE36941.1 - 1.8e-07 31.6 0.1 0.035 14.6 0.0 3.3 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 EKE36941.1 - 4.8e-07 29.1 0.8 0.0037 16.4 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE36941.1 - 1.1e-06 28.8 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EKE36941.1 - 1.8e-06 27.9 1.8 0.067 13.1 0.1 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKE36941.1 - 3.7e-06 26.8 0.2 0.033 14.0 0.0 3.1 3 0 0 3 3 3 2 Dynamin family Arch_ATPase PF01637.13 EKE36941.1 - 8.8e-06 25.5 0.2 0.028 14.1 0.0 2.9 2 0 0 2 2 2 2 Archaeal ATPase AAA_29 PF13555.1 EKE36941.1 - 9.8e-06 25.0 0.2 0.059 12.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EKE36941.1 - 9e-05 22.7 0.0 0.15 12.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKE36941.1 - 0.00015 21.2 1.2 0.015 14.7 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EKE36941.1 - 0.00015 22.5 0.4 0.94 10.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKE36941.1 - 0.00025 21.1 8.9 0.22 11.6 0.0 4.6 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.1 EKE36941.1 - 0.00026 21.3 8.6 0.0095 16.2 0.2 3.9 3 2 0 3 3 2 2 AAA domain NACHT PF05729.7 EKE36941.1 - 0.00027 20.6 0.4 0.083 12.5 0.0 3.1 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EKE36941.1 - 0.0003 20.2 0.4 0.059 12.8 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EKE36941.1 - 0.00068 19.3 1.8 0.16 11.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EKE36941.1 - 0.00084 18.8 0.3 0.86 9.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EKE36941.1 - 0.001 18.5 0.8 0.76 9.2 0.1 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EKE36941.1 - 0.0018 17.3 0.0 0.1 11.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin KAP_NTPase PF07693.9 EKE36941.1 - 0.0019 17.2 0.0 0.61 9.0 0.0 2.5 2 0 0 2 2 2 1 KAP family P-loop domain AAA PF00004.24 EKE36941.1 - 0.0045 17.1 1.0 0.13 12.4 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EKE36941.1 - 0.0058 15.5 0.9 0.32 9.8 0.1 2.6 2 0 0 2 2 2 1 NB-ARC domain DUF87 PF01935.12 EKE36941.1 - 0.0061 16.3 1.2 0.027 14.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EKE36941.1 - 0.0076 15.6 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKE36941.1 - 0.0084 15.5 2.8 0.71 9.2 0.0 2.8 3 0 0 3 3 2 1 AAA-like domain GTP_EFTU PF00009.22 EKE36941.1 - 0.0091 15.4 0.1 0.31 10.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain UPF0079 PF02367.12 EKE36941.1 - 0.01 15.4 0.4 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EKE36941.1 - 0.013 14.9 0.1 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 EKE36941.1 - 0.015 15.2 0.0 4.1 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EKE36941.1 - 0.018 14.5 1.0 4.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EKE36941.1 - 0.02 15.0 0.1 8.5 6.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 EKE36941.1 - 0.036 12.9 0.1 4.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ArgK PF03308.11 EKE36941.1 - 0.099 11.4 0.1 3.5 6.3 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 EKE36941.1 - 0.099 12.2 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EKE36941.1 - 0.099 12.4 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain TrwB_AAD_bind PF10412.4 EKE36941.1 - 0.14 10.7 0.3 8.3 4.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 EKE36941.1 - 0.18 11.4 6.0 0.29 10.8 0.1 3.4 4 0 0 4 4 3 0 NTPase AAA_28 PF13521.1 EKE36941.1 - 0.22 11.5 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_S17 PF00366.15 EKE36942.1 - 1e-26 92.7 1.8 1e-26 92.7 1.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 CSD PF00313.17 EKE36942.1 - 0.18 11.5 1.8 12 5.7 0.0 3.3 2 1 1 3 3 3 0 'Cold-shock' DNA-binding domain Pkinase_Tyr PF07714.12 EKE36943.1 - 1.5e-46 158.5 0.0 2.6e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE36943.1 - 3.2e-42 144.4 0.0 5.6e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EKE36944.1 - 1.2e-30 102.7 12.5 3.5e-05 23.5 0.0 11.8 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 EKE36944.1 - 2.8e-18 65.9 0.0 3.7e-05 23.9 0.0 6.4 1 1 6 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.2 EKE36944.1 - 9.5e-08 32.3 4.6 0.15 12.4 0.0 5.6 3 1 3 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EKE36944.1 - 3e-06 25.8 13.6 0.00021 19.7 0.1 3.3 3 1 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.3 EKE36944.1 - 0.00049 19.5 2.0 0.049 12.9 0.7 3.7 2 1 1 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.1 EKE36944.1 - 0.0017 18.8 0.2 15 6.2 0.0 5.9 6 2 2 8 8 8 1 HEAT-like repeat DNA_alkylation PF08713.6 EKE36944.1 - 0.024 14.1 0.0 0.31 10.5 0.0 2.4 2 1 1 3 3 3 0 DNA alkylation repair enzyme Arm PF00514.18 EKE36944.1 - 0.25 11.2 2.3 25 4.8 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Pyrophosphatase PF00719.14 EKE36945.1 - 9.1e-43 145.3 0.4 1.2e-42 145.0 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Kinesin PF00225.18 EKE36946.1 - 2.5e-91 305.8 0.3 2.5e-91 305.8 0.2 3.6 2 1 0 2 2 2 1 Kinesin motor domain Arm PF00514.18 EKE36947.1 - 0.00045 19.9 0.1 0.7 9.8 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 EKE36947.1 - 0.018 14.9 0.8 5.9 6.8 0.0 4.3 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Pkinase PF00069.20 EKE36948.1 - 1e-08 34.6 0.3 1e-08 34.6 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE36948.1 - 0.00035 19.7 0.0 0.00035 19.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKE36948.1 - 0.026 13.3 0.5 0.026 13.3 0.4 1.0 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EKE36949.1 - 1.2e-13 50.8 0.1 1.5e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE36949.1 - 6.6e-12 45.0 0.2 7.5e-12 44.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PAP2 PF01569.16 EKE36950.1 - 7.2e-07 28.9 0.6 7.2e-07 28.9 0.4 2.0 2 1 0 2 2 2 1 PAP2 superfamily Snf7 PF03357.16 EKE36951.1 - 3.8e-24 84.9 36.2 5.9e-24 84.3 25.1 1.4 1 1 0 1 1 1 1 Snf7 TPR_21 PF09976.4 EKE36951.1 - 0.035 14.0 1.5 0.035 14.0 1.1 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Amidohydro_1 PF01979.15 EKE36951.1 - 3 7.3 6.4 5.6 6.5 4.3 1.3 1 1 0 1 1 1 0 Amidohydrolase family PspA_IM30 PF04012.7 EKE36951.1 - 3.1 7.1 30.4 0.2 11.0 5.1 3.0 1 1 1 3 3 3 0 PspA/IM30 family HemY_N PF07219.8 EKE36951.1 - 3.4 7.2 6.5 0.39 10.3 1.3 1.8 2 0 0 2 2 2 0 HemY protein N-terminus WGG PF10273.4 EKE36952.1 - 2.1e-18 66.2 1.0 3.2e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Nop14 PF04147.7 EKE36952.1 - 0.071 11.0 21.8 0.069 11.0 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EKE36952.1 - 0.12 11.4 20.6 0.17 11.0 14.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 EKE36952.1 - 0.33 10.3 20.6 0.4 10.0 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EKE36952.1 - 1.1 8.4 27.1 1.7 7.8 18.8 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 EKE36952.1 - 4.3 4.8 7.8 4.2 4.9 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EKE36952.1 - 4.6 5.1 20.2 5.6 4.8 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0047 PF01894.12 EKE36953.1 - 1.5e-40 137.6 0.0 1.7e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RabGAP-TBC PF00566.13 EKE36954.1 - 4.9e-22 78.4 11.3 4.9e-22 78.4 7.8 3.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Lactamase_B_2 PF12706.2 EKE36955.1 - 1e-16 61.0 0.1 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.10 EKE36955.1 - 1.7e-10 40.3 4.3 2e-08 33.5 3.0 2.2 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B PF00753.22 EKE36955.1 - 8.6e-08 32.0 0.1 2.8e-06 27.1 0.1 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Myb_DNA-bind_4 PF13837.1 EKE36956.1 - 0.1 12.7 0.3 0.71 10.0 0.1 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Biliv-reduc_cat PF09166.5 EKE36957.1 - 0.03 14.3 0.2 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 Biliverdin reductase, catalytic AAA_30 PF13604.1 EKE36957.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.17 EKE36958.1 - 1.5e-24 85.5 4.8 2.1e-24 85.0 3.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.1 EKE36958.1 - 0.32 10.6 3.5 0.55 9.8 2.1 1.6 1 1 1 2 2 2 0 MafB19-like deaminase Bd3614-deam PF14439.1 EKE36958.1 - 0.39 10.5 5.0 5.4 6.8 2.0 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase Claudin_2 PF13903.1 EKE36959.1 - 0.00048 19.8 16.4 0.00048 19.8 11.4 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 EKE36959.1 - 0.00072 19.1 10.5 0.00072 19.1 7.2 2.3 1 1 1 2 2 2 1 SUR7/PalI family DUF4293 PF14126.1 EKE36959.1 - 0.065 13.1 7.9 30 4.5 5.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF973 PF06157.6 EKE36959.1 - 1.7 7.5 14.5 0.12 11.3 2.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF973) 7tm_7 PF08395.7 EKE36959.1 - 5.1 6.0 15.1 0.12 11.3 5.7 1.8 2 1 0 2 2 2 0 7tm Chemosensory receptor MARVEL PF01284.18 EKE36959.1 - 9.7 6.0 16.0 54 3.5 11.1 2.3 1 1 0 1 1 1 0 Membrane-associating domain Claudin_3 PF06653.6 EKE36959.1 - 9.7 5.8 17.3 55 3.4 12.0 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like RRM_1 PF00076.17 EKE36960.1 - 3.7e-16 58.5 0.0 5.3e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE36960.1 - 5.2e-11 42.3 0.0 6.6e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE36960.1 - 8.5e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE36960.1 - 0.022 14.5 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_transf_20 PF00982.16 EKE36960.1 - 0.046 12.1 0.1 0.061 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 DUF2963 PF11178.3 EKE36962.1 - 0.57 9.6 3.4 7.1 6.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) UPF0184 PF03670.8 EKE36963.1 - 0.18 12.0 1.1 20 5.4 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) zf-DHHC PF01529.15 EKE36965.1 - 9.1e-32 109.8 21.6 9.1e-32 109.8 15.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF161 PF02588.10 EKE36965.1 - 0.00014 22.1 3.9 0.0018 18.5 0.0 2.4 1 1 1 2 2 2 1 Uncharacterized BCR, YitT family COG1284 WWE PF02825.15 EKE36967.1 - 1.2e-09 37.4 8.8 2.1e-07 30.2 3.8 3.1 2 1 0 2 2 2 2 WWE domain Thioredoxin_8 PF13905.1 EKE36967.1 - 0.025 14.7 0.2 0.077 13.1 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.16 EKE36967.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family Ferric_reduct PF01794.14 EKE36969.1 - 5.6e-07 29.6 5.1 2e-06 27.9 3.5 2.0 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EKE36969.1 - 8.9e-05 22.3 0.2 0.0021 17.8 0.1 2.4 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EKE36969.1 - 0.0001 22.2 0.0 0.0026 17.6 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EKE36969.1 - 0.05 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Acetate_kinase PF00871.12 EKE36970.1 - 6.5e-95 317.9 0.4 7.3e-95 317.7 0.3 1.0 1 0 0 1 1 1 1 Acetokinase family Glyco_hydro_2_N PF02837.13 EKE36971.1 - 2.6e-19 69.4 3.3 6.2e-19 68.1 2.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EKE36971.1 - 1.4e-05 25.5 0.0 3.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EKE36971.1 - 0.00056 18.8 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain WD40 PF00400.27 EKE36972.1 - 5.6e-14 51.4 14.8 2.2e-07 30.4 0.0 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat F-box PF00646.28 EKE36972.1 - 0.033 13.8 0.1 0.1 12.2 0.1 1.9 1 0 0 1 1 1 0 F-box domain Synaptobrevin PF00957.16 EKE36973.1 - 3.9e-28 96.8 0.1 6.7e-28 96.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EKE36973.1 - 7.9e-15 54.1 0.3 1.2e-14 53.5 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Fusion_gly PF00523.13 EKE36973.1 - 0.098 10.7 0.1 0.12 10.3 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Gasdermin PF04598.7 EKE36973.1 - 0.1 11.3 0.3 0.13 10.9 0.2 1.1 1 0 0 1 1 1 0 Gasdermin family CUE PF02845.11 EKE36974.1 - 4.6e-06 26.0 0.2 1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 CUE domain Rad60-SLD PF11976.3 EKE36975.1 - 2.1e-22 78.5 0.2 2.7e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EKE36975.1 - 1.6e-09 36.9 0.1 2.1e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Vasohibin PF14822.1 EKE36975.1 - 0.043 12.9 0.1 0.048 12.7 0.1 1.1 1 0 0 1 1 1 0 Vasohibin YukD PF08817.5 EKE36975.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD SMC_Nse1 PF07574.8 EKE36976.1 - 0.0082 15.7 1.6 0.011 15.3 1.1 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Filo_VP35 PF02097.10 EKE36976.1 - 0.094 11.8 1.4 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 DUF4064 PF13273.1 EKE36976.1 - 0.33 11.0 3.7 1.4 9.0 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) AKNA PF12443.3 EKE36976.1 - 0.47 10.4 5.3 2.5 8.1 0.4 3.0 2 1 0 3 3 3 0 AT-hook-containing transcription factor Lipase_GDSL PF00657.17 EKE36977.1 - 6.6e-06 26.1 4.6 0.00012 21.9 3.2 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKE36977.1 - 0.00028 21.0 0.9 0.0022 18.1 0.7 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SAC3_GANP PF03399.11 EKE36978.1 - 0.15 11.5 7.3 0.24 10.9 5.0 1.4 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Reo_sigmaC PF04582.7 EKE36982.1 - 0.031 13.4 3.8 0.1 11.7 1.2 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Acetyltransf_1 PF00583.19 EKE36983.1 - 3.6e-12 46.1 0.0 5.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKE36983.1 - 3.2e-09 36.4 0.0 4.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKE36983.1 - 3.3e-08 33.8 0.0 4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKE36983.1 - 1.1e-06 28.5 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE36983.1 - 2.1e-06 27.8 0.0 2.8e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKE36983.1 - 5.3e-06 26.5 0.0 9.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EKE36983.1 - 9.6e-05 21.3 0.1 0.00013 20.8 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_4 PF13420.1 EKE36983.1 - 0.00021 21.2 0.2 0.00026 20.9 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE36983.1 - 0.0027 17.5 0.0 0.0088 15.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DAGK_prokar PF01219.14 EKE36983.1 - 0.076 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase UMP1 PF05348.6 EKE36986.1 - 0.081 12.8 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 LRR_1 PF00560.28 EKE36989.1 - 2.6 8.4 5.7 4.6 7.6 0.7 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.20 EKE36990.1 - 1.1e-56 191.9 0.4 1.5e-54 184.9 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE36990.1 - 1.5e-33 115.9 0.1 1.6e-32 112.5 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE36990.1 - 0.003 16.5 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE36990.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2404 PF10296.4 EKE36991.1 - 0.0022 18.0 0.0 0.0081 16.2 0.0 2.1 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Methylase_S PF01420.14 EKE36992.1 - 0.15 11.9 2.8 0.27 11.2 2.0 1.4 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain IncA PF04156.9 EKE36993.1 - 0.042 13.4 3.4 0.25 10.9 0.0 2.3 2 0 0 2 2 2 0 IncA protein Pox_P21 PF05313.7 EKE36993.1 - 0.056 12.6 2.8 0.082 12.1 2.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Sensor PF13796.1 EKE36993.1 - 0.27 10.8 16.0 0.73 9.4 9.4 2.5 2 1 1 3 3 3 0 Putative sensor Myc_target_1 PF15179.1 EKE36993.1 - 3.4 7.1 4.9 0.29 10.6 0.2 1.8 2 0 0 2 2 2 0 Myc target protein 1 DUF1469 PF07332.6 EKE36993.1 - 4 7.1 20.1 1.9 8.2 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1461 PF07314.6 EKE36993.1 - 4.9 6.8 14.5 0.52 10.0 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1461) RseC_MucC PF04246.7 EKE36993.1 - 6 6.4 6.7 3.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MBOAT PF03062.14 EKE36993.1 - 7.7 5.5 14.9 16 4.4 10.3 1.6 1 1 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family PRCC PF10253.4 EKE36994.1 - 7.5e-05 23.4 8.8 9.4e-05 23.1 6.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Dppa2_A PF14049.1 EKE36994.1 - 0.21 11.4 2.6 0.11 12.3 0.5 1.5 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates eIF3_N PF09440.5 EKE36994.1 - 0.43 10.7 5.2 0.26 11.4 2.2 1.6 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Pkinase_Tyr PF07714.12 EKE36995.1 - 3.4e-61 206.5 0.0 4.9e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE36995.1 - 9.3e-57 192.1 0.0 1.4e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 EKE36995.1 - 3.9e-05 23.5 11.5 0.0024 17.8 1.1 3.5 4 0 0 4 4 4 2 IPT/TIG domain APH PF01636.18 EKE36995.1 - 0.00052 19.8 0.0 0.4 10.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Tweety PF04906.8 EKE36996.1 - 0.00037 19.0 15.1 0.0031 15.9 8.3 2.9 2 1 0 2 2 2 1 Tweety CAMP_factor PF07373.6 EKE36996.1 - 0.024 14.1 0.2 0.08 12.4 0.0 1.9 2 0 0 2 2 2 0 CAMP factor (Cfa) UBN2_2 PF14227.1 EKE36996.1 - 0.065 12.7 0.2 1 8.9 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TMEM154 PF15102.1 EKE36996.1 - 0.14 11.9 11.5 4.8 6.8 3.1 3.9 4 0 0 4 4 4 0 TMEM154 protein family Inositol_P PF00459.20 EKE36997.1 - 3.3e-35 121.6 0.0 6.7e-35 120.6 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family PMM PF03332.8 EKE36998.1 - 6.9e-83 277.5 4.2 8.4e-83 277.2 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EKE36998.1 - 3.9e-10 39.7 1.0 9.8e-10 38.4 0.7 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKE36998.1 - 9.3e-05 21.8 0.0 0.061 12.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase GAD-like PF08887.6 EKE36998.1 - 0.027 14.5 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 GAD-like domain PNK3P PF08645.6 EKE36998.1 - 0.042 13.2 0.2 0.39 10.1 0.1 2.5 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.21 EKE36998.1 - 0.045 14.1 0.1 0.077 13.4 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE36998.1 - 0.15 12.2 1.6 1.7 8.7 0.7 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RdRP PF05183.7 EKE36999.1 - 8.4e-27 94.1 0.7 1.3e-26 93.5 0.5 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Acetyltransf_11 PF13720.1 EKE36999.1 - 0.23 11.7 2.3 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DPBB_1 PF03330.13 EKE37000.1 - 8e-07 28.9 0.2 3.4e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF43 PF01861.11 EKE37000.1 - 0.094 11.6 0.3 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 DTW PF03942.10 EKE37003.1 - 1.4e-17 63.6 0.0 2.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.19 EKE37003.1 - 0.018 14.9 1.9 0.047 13.5 1.3 1.7 1 0 0 1 1 1 0 B-box zinc finger zf-RING_3 PF14369.1 EKE37003.1 - 0.098 12.6 2.1 3.3 7.7 0.3 2.5 2 0 0 2 2 2 0 zinc-finger CS PF04969.11 EKE37004.1 - 2.4e-15 56.8 2.2 3.4e-15 56.3 1.5 1.2 1 0 0 1 1 1 1 CS domain UQ_con PF00179.21 EKE37005.1 - 8.5e-49 164.5 0.0 9.6e-49 164.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKE37005.1 - 0.0084 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B WD40 PF00400.27 EKE37006.1 - 6.1e-05 22.7 7.1 0.087 12.7 0.3 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Pkinase PF00069.20 EKE37007.1 - 7e-69 231.8 0.3 8.6e-69 231.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37007.1 - 5.5e-37 127.2 0.0 6.9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37007.1 - 5.9e-06 25.4 0.0 1.1e-05 24.5 0.0 1.5 1 1 1 2 2 2 1 Kinase-like FHA PF00498.21 EKE37007.1 - 0.0044 17.1 1.0 0.0091 16.0 0.2 2.0 2 0 0 2 2 2 1 FHA domain Kdo PF06293.9 EKE37007.1 - 0.026 13.5 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L38e PF01781.13 EKE37009.1 - 2.5e-20 71.9 2.3 3.1e-20 71.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family RTP PF02334.11 EKE37009.1 - 0.079 12.9 0.5 0.098 12.6 0.4 1.2 1 0 0 1 1 1 0 Replication terminator protein SNF2_N PF00176.18 EKE37010.1 - 3.6e-72 242.6 0.2 6.3e-72 241.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE37010.1 - 8.3e-16 57.6 0.1 4.7e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EKE37010.1 - 3.9e-05 23.8 0.5 1.9 8.8 0.0 4.7 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EKE37010.1 - 0.0018 18.1 0.1 1.6 9.0 0.0 5.3 7 0 0 7 7 7 1 HEAT repeat TLD PF07534.11 EKE37011.1 - 0.00016 21.6 3.3 0.00033 20.6 2.3 1.6 1 1 0 1 1 1 1 TLD TLD PF07534.11 EKE37012.1 - 0.00036 20.5 0.6 0.00099 19.1 0.1 2.0 2 1 0 2 2 2 1 TLD MRP-S32 PF10210.4 EKE37012.1 - 0.1 12.9 0.5 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 PQQ_2 PF13360.1 EKE37013.1 - 0.068 12.6 0.0 9 5.6 0.0 3.2 3 1 0 3 3 3 0 PQQ-like domain Gtr1_RagA PF04670.7 EKE37014.1 - 1.2e-79 266.7 1.9 1.5e-79 266.3 1.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EKE37014.1 - 1e-09 37.9 0.4 2.5e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE37014.1 - 1.1e-09 37.8 0.1 1.6e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE37014.1 - 5.4e-06 26.8 0.1 1.5e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EKE37014.1 - 3.8e-05 22.9 0.1 6.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE37014.1 - 6.4e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EKE37014.1 - 0.0034 16.8 0.1 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EKE37014.1 - 0.0068 15.8 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EKE37014.1 - 0.0084 16.4 0.1 0.021 15.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EKE37014.1 - 0.019 13.9 0.7 0.24 10.3 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF815) FBA_3 PF08268.7 EKE37014.1 - 0.023 14.4 1.4 0.75 9.5 0.9 2.5 1 1 0 1 1 1 0 F-box associated domain AAA_29 PF13555.1 EKE37014.1 - 0.073 12.6 0.1 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EKE37014.1 - 0.13 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FNIP PF05725.7 EKE37015.1 - 0.014 15.3 15.0 2.3 8.2 0.0 5.6 5 1 0 5 5 5 0 FNIP Repeat bZIP_Maf PF03131.12 EKE37016.1 - 5.9e-19 68.1 9.5 5.9e-19 68.1 6.6 2.4 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EKE37016.1 - 0.0001 22.1 14.8 0.0001 22.1 10.2 2.7 2 1 2 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.10 EKE37016.1 - 0.0002 21.0 11.3 0.0002 21.0 7.8 2.6 2 1 0 3 3 2 1 Basic region leucine zipper DUF2810 PF10928.3 EKE37016.1 - 0.071 12.8 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) CMV_1a PF12467.3 EKE37016.1 - 0.2 11.9 4.9 0.44 10.8 3.4 1.5 1 1 0 1 1 1 0 Cucumber mosaic virus 1a protein family NPV_P10 PF05531.7 EKE37016.1 - 0.29 11.4 3.0 0.29 11.4 0.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EKE37016.1 - 0.37 10.3 8.6 0.47 10.0 6.0 1.2 1 0 0 1 1 1 0 IncA protein HCV_NS5a_C PF12941.2 EKE37016.1 - 0.54 9.7 3.7 0.72 9.3 2.5 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region CDC37_C PF08564.5 EKE37016.1 - 0.62 9.9 4.7 0.2 11.4 1.2 1.7 2 0 0 2 2 2 0 Cdc37 C terminal domain APG6 PF04111.7 EKE37016.1 - 0.69 8.9 11.1 0.96 8.4 7.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DIRP PF06584.8 EKE37016.1 - 2.5 7.9 7.9 5.2 6.9 0.3 2.3 1 1 1 2 2 2 0 DIRP V_ATPase_I PF01496.14 EKE37016.1 - 3.3 5.4 6.8 4.6 4.9 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1192 PF06698.6 EKE37016.1 - 3.9 7.3 6.3 1.9 8.3 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Clat_adaptor_s PF01217.15 EKE37017.1 - 1.6e-48 164.0 2.8 1.8e-48 163.9 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TLD PF07534.11 EKE37018.1 - 0.0028 17.6 0.8 0.0028 17.6 0.5 1.9 2 0 0 2 2 2 1 TLD Presenilin PF01080.12 EKE37018.1 - 0.48 9.1 3.9 0.67 8.7 2.7 1.1 1 0 0 1 1 1 0 Presenilin Allexi_40kDa PF05549.6 EKE37018.1 - 0.56 9.4 6.2 0.22 10.8 2.7 1.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein Not1 PF04054.10 EKE37019.1 - 2.9e-16 59.3 18.9 6.8e-14 51.5 5.0 3.3 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EKE37019.1 - 7e-07 29.0 3.2 7e-07 29.0 2.2 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3819) Ras PF00071.17 EKE37020.1 - 1.5e-51 174.0 1.3 1.8e-51 173.7 0.9 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37020.1 - 8.2e-16 58.5 0.4 1.7e-15 57.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE37020.1 - 1.2e-11 44.1 0.1 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE37020.1 - 8.1e-11 41.6 0.2 5.9e-10 38.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE37020.1 - 1.8e-06 27.2 0.3 3.4e-06 26.3 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE37020.1 - 3.3e-06 27.0 0.0 5.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EKE37020.1 - 2.3e-05 24.4 0.0 3.1e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EKE37020.1 - 8.1e-05 21.9 0.0 0.00018 20.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 EKE37020.1 - 0.001 18.8 0.1 0.0027 17.4 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EKE37020.1 - 0.0011 18.6 0.7 0.023 14.2 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EKE37020.1 - 0.0012 18.9 0.0 0.0048 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE37020.1 - 0.0023 18.7 0.0 0.0037 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKE37020.1 - 0.004 17.0 0.1 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EKE37020.1 - 0.0047 16.4 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE37020.1 - 0.0052 15.9 0.2 0.01 15.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EKE37020.1 - 0.0063 15.5 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_10 PF12846.2 EKE37020.1 - 0.012 15.0 0.1 0.11 11.8 0.1 2.0 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EKE37020.1 - 0.028 14.2 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKE37020.1 - 0.034 13.8 0.0 0.058 13.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 EKE37020.1 - 0.039 13.2 0.2 0.6 9.3 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.1 EKE37020.1 - 0.066 13.5 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EKE37020.1 - 0.071 13.3 0.0 0.41 10.8 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EKE37020.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EKE37020.1 - 0.081 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EKE37020.1 - 0.084 12.8 0.1 0.28 11.1 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EKE37020.1 - 0.089 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Dynamin_N PF00350.18 EKE37020.1 - 0.33 10.7 2.6 0.48 10.2 0.1 2.2 2 1 1 3 3 3 0 Dynamin family Glyco_transf_8 PF01501.15 EKE37021.1 - 0.015 14.6 0.5 0.015 14.6 0.3 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 LRR_5 PF13306.1 EKE37022.1 - 8.2e-93 306.8 36.4 8.8e-32 109.5 4.5 4.3 3 1 1 4 4 4 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37022.1 - 4.6e-36 122.3 8.1 3.6e-08 33.0 0.1 7.4 3 2 5 8 8 8 8 Leucine rich repeat FNIP PF05725.7 EKE37022.1 - 0.92 9.5 0.0 0.92 9.5 0.0 6.9 6 1 2 8 8 8 0 FNIP Repeat DUF3184 PF11380.3 EKE37024.1 - 1.3e-05 23.3 0.2 0.17 9.8 0.0 3.3 3 1 0 3 3 3 3 Protein of unknown function (DUF3184) DUF3184 PF11380.3 EKE37025.1 - 9.1e-11 40.4 5.1 1.8e-05 22.9 0.0 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF3184) APS_kinase PF01583.15 EKE37026.1 - 4.1e-59 198.7 0.0 6.1e-59 198.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EKE37026.1 - 1.8e-18 66.4 0.0 3.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EKE37026.1 - 1.6e-07 31.2 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKE37026.1 - 0.00044 20.2 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EKE37026.1 - 0.0089 15.1 0.0 0.022 13.8 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 EKE37026.1 - 0.024 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EKE37026.1 - 0.025 15.4 0.0 0.051 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKE37026.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 EKE37026.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EKE37026.1 - 0.047 12.6 0.0 0.1 11.4 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EKE37026.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_6 PF13405.1 EKE37027.1 - 1.1 9.3 9.6 0.96 9.5 0.2 3.5 3 0 0 3 3 3 0 EF-hand domain DUF2203 PF09969.4 EKE37028.1 - 0.37 11.0 2.7 0.28 11.3 1.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.17 EKE37028.1 - 7.6 6.5 12.5 1.5 8.8 5.2 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.1 EKE37028.1 - 8.3 6.2 7.2 8.8 6.1 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Nrap PF03813.9 EKE37029.1 - 1e-53 182.2 3.0 1.4e-36 125.4 0.3 3.0 3 0 0 3 3 3 3 Nrap protein ocr PF08684.5 EKE37029.1 - 0.041 13.9 0.3 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 DNA mimic ocr Lactamase_B PF00753.22 EKE37031.1 - 2.1e-14 53.6 0.1 1.3e-13 51.0 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Flavodoxin_1 PF00258.20 EKE37031.1 - 2.2e-06 27.7 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin DUF1256 PF06866.6 EKE37031.1 - 0.012 14.7 2.9 0.35 10.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1256) FMN_red PF03358.10 EKE37031.1 - 0.022 14.2 0.0 0.086 12.3 0.0 1.9 1 1 0 1 1 1 0 NADPH-dependent FMN reductase Lactamase_B_2 PF12706.2 EKE37031.1 - 0.075 12.5 0.3 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CbiX PF01903.12 EKE37031.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 CbiX Methyltransf_16 PF10294.4 EKE37033.1 - 2.1e-16 59.8 0.2 2.8e-16 59.4 0.2 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EKE37033.1 - 6.7e-09 35.5 0.8 9.2e-09 35.0 0.5 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE37033.1 - 1.1e-05 25.9 0.0 1.5e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE37033.1 - 1.6e-05 25.2 0.1 3.6e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EKE37033.1 - 3.1e-05 23.6 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 EKE37033.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EKE37033.1 - 0.042 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.7 EKE37033.1 - 0.055 13.9 0.0 0.089 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EKE37033.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LRR_1 PF00560.28 EKE37034.1 - 2.7 8.3 7.9 1.1e+02 3.5 1.6 5.2 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 EKE37034.1 - 8.1 6.1 14.4 4.2 7.1 0.4 4.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Ssu72 PF04722.8 EKE37035.1 - 4.5e-46 156.6 0.9 5.2e-46 156.4 0.6 1.0 1 0 0 1 1 1 1 Ssu72-like protein AMP-binding PF00501.23 EKE37036.1 - 1.9e-83 280.2 0.0 2.7e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MIG-14_Wnt-bd PF06664.7 EKE37037.1 - 4.2e-79 265.4 35.3 4.2e-79 265.4 24.5 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF2839 PF10999.3 EKE37037.1 - 2.2 8.3 4.0 44 4.2 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Prenyltrans PF00432.16 EKE37038.1 - 1.1e-63 210.4 10.9 1.1e-13 50.4 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKE37038.1 - 6.5e-30 103.8 0.0 6.6e-17 61.9 0.0 3.7 2 2 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EKE37038.1 - 8.7e-09 35.3 0.0 5.4e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 Prenyltransferase-like RhoGAP PF00620.22 EKE37039.1 - 1.2e-10 41.2 0.5 6.2e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Nop52 PF05997.7 EKE37039.1 - 0.016 14.6 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Nucleolar protein,Nop52 SPATIAL PF15256.1 EKE37039.1 - 0.063 13.3 1.9 0.11 12.5 1.3 1.4 1 0 0 1 1 1 0 SPATIAL GCC2_GCC3 PF07699.8 EKE37040.1 - 0.00016 21.1 51.6 0.0012 18.3 6.1 5.9 2 1 3 5 5 5 5 GCC2 and GCC3 NCD3G PF07562.9 EKE37040.1 - 0.0019 17.8 43.0 0.044 13.5 0.5 6.5 3 1 1 5 5 5 3 Nine Cysteines Domain of family 3 GPCR DUF4315 PF14193.1 EKE37041.1 - 0.026 14.4 5.2 0.044 13.7 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) TcpA PF05946.7 EKE37041.1 - 0.09 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA ubiquitin PF00240.18 EKE37042.1 - 8.1e-10 37.9 0.0 1.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE37042.1 - 0.0007 19.2 0.0 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Flo11 PF10182.4 EKE37042.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Flo11 domain Reo_sigmaC PF04582.7 EKE37044.1 - 0.33 10.0 3.6 0.73 8.9 2.5 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FUSC-like PF12805.2 EKE37044.1 - 6.7 5.5 5.1 15 4.4 3.5 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS RasGAP PF00616.14 EKE37045.1 - 1.2e-09 38.1 9.3 1.6e-09 37.7 3.6 2.7 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase HALZ PF02183.13 EKE37045.1 - 0.058 13.1 4.4 0.1 12.3 1.3 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper RasGAP PF00616.14 EKE37046.1 - 1.4e-25 90.1 3.9 1.4e-25 90.1 2.7 3.5 4 1 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EKE37046.1 - 1e-17 64.1 9.0 1e-17 64.1 6.2 2.5 2 0 0 2 2 2 1 RasGAP C-terminus BAR PF03114.13 EKE37047.1 - 3.5e-07 29.9 3.8 3.5e-07 29.9 2.6 2.1 2 0 0 2 2 2 1 BAR domain Topo_C_assoc PF14370.1 EKE37047.1 - 0.031 13.9 0.1 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 C-terminal topoisomerase domain COG2 PF06148.6 EKE37047.1 - 0.034 14.0 0.8 0.31 10.9 0.2 2.5 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.3 EKE37047.1 - 0.078 10.2 10.3 0.1 9.9 6.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 EKE37047.1 - 0.093 12.3 7.6 0.15 11.6 0.6 2.6 2 1 0 2 2 2 0 IncA protein Syntaxin-6_N PF09177.6 EKE37047.1 - 0.17 12.2 4.5 0.51 10.7 0.7 2.9 2 2 0 2 2 2 0 Syntaxin 6, N-terminal GP41 PF00517.12 EKE37047.1 - 0.24 10.9 3.8 0.27 10.7 0.6 2.2 1 1 0 2 2 2 0 Retroviral envelope protein Ded_cyto PF06920.8 EKE37047.1 - 0.63 9.3 5.6 4.7 6.4 0.9 3.1 1 1 2 3 3 3 0 Dedicator of cytokinesis OmpH PF03938.9 EKE37047.1 - 0.94 9.4 8.3 3.9 7.3 5.8 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FliD_C PF07195.7 EKE37047.1 - 1 8.5 8.5 1.2 8.4 0.1 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus FTCD_C PF04961.7 EKE37047.1 - 1.2 8.5 6.7 1.3 8.3 3.4 1.9 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase TPR_MLP1_2 PF07926.7 EKE37047.1 - 1.4 8.6 15.4 1.5 8.6 3.2 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Z1 PF10593.4 EKE37047.1 - 9.3 5.3 9.2 10 5.2 0.8 2.5 1 1 2 3 3 3 0 Z1 domain HORMA PF02301.13 EKE37048.1 - 0.00027 20.4 2.4 0.0003 20.3 1.2 1.4 1 1 0 1 1 1 1 HORMA domain RhoGEF PF00621.15 EKE37049.1 - 7.2e-36 123.7 11.4 8.3e-36 123.5 5.8 2.6 2 0 0 2 2 2 1 RhoGEF domain ArfGap PF01412.13 EKE37049.1 - 5.3e-13 48.7 0.2 5.3e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EKE37049.1 - 4.4e-11 42.8 1.3 0.00051 20.1 0.0 3.7 3 0 0 3 3 3 2 PH domain PH_6 PF15406.1 EKE37049.1 - 0.021 14.8 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain COX16 PF14138.1 EKE37049.1 - 9.5 6.4 15.3 7.2 6.8 7.0 3.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Macoilin PF09726.4 EKE37050.1 - 0.49 8.6 4.5 0.59 8.3 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein GET2 PF08690.5 EKE37050.1 - 1.1 8.4 4.7 0.34 10.1 1.3 1.5 1 1 0 1 1 1 0 GET complex subunit GET2 LCAT PF02450.10 EKE37051.1 - 1.1e-34 120.0 4.1 2.3e-32 112.4 0.1 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EKE37051.1 - 5.6e-06 26.1 0.0 1.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 EKE37051.1 - 0.0028 16.9 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EKE37051.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE37051.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EKE37051.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) HSP70 PF00012.15 EKE37053.1 - 7.3e-08 30.7 17.7 7.5e-06 24.1 0.4 3.6 3 1 1 4 4 4 3 Hsp70 protein RNA_pol_Rpb2_4 PF04566.8 EKE37053.1 - 0.036 13.8 0.1 0.18 11.6 0.1 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 MoCF_biosynth PF00994.19 EKE37053.1 - 0.05 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Probable molybdopterin binding domain Adeno_E3_CR1 PF02440.10 EKE37053.1 - 0.1 12.1 0.2 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 RPEL PF02755.10 EKE37054.1 - 0.081 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 RPEL repeat RhoGAP PF00620.22 EKE37055.1 - 2.8e-13 49.7 0.0 4.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DAG_kinase_N PF14513.1 EKE37055.1 - 0.035 14.2 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus EKR PF10371.4 EKE37055.1 - 0.15 11.6 0.1 0.56 9.8 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function Ded_cyto PF06920.8 EKE37056.1 - 1.5e-05 24.4 1.3 1.5e-05 24.4 0.9 3.5 4 1 0 4 4 4 1 Dedicator of cytokinesis RhoGEF PF00621.15 EKE37057.1 - 3.1e-36 124.9 0.5 6.7e-36 123.8 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EKE37057.1 - 1.7e-07 31.0 9.4 1.7e-07 31.0 6.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 EKE37057.1 - 2.7e-05 24.3 2.4 3.7e-05 23.8 0.1 2.5 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.11 EKE37057.1 - 0.23 11.3 9.8 0.033 14.1 3.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_2 PF14445.1 EKE37057.1 - 0.69 9.8 6.6 1.8 8.5 4.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 UQ_con PF00179.21 EKE37059.1 - 6.5e-44 148.7 0.2 8.3e-44 148.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKE37059.1 - 0.00036 20.2 0.0 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B VCBS PF13517.1 EKE37060.1 - 8e-08 32.5 0.5 0.015 15.6 0.0 4.4 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.1 EKE37060.1 - 4.5e-05 23.0 0.0 1.6 8.1 0.0 3.9 3 1 0 4 4 4 2 PQQ-like domain FG-GAP PF01839.18 EKE37060.1 - 0.00048 19.7 5.5 0.0022 17.6 0.0 3.2 3 0 0 3 3 3 1 FG-GAP repeat PQQ PF01011.16 EKE37060.1 - 0.051 13.1 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Ras PF00071.17 EKE37061.1 - 1.7e-14 53.5 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37061.1 - 2.5e-07 31.2 0.0 3.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE37061.1 - 6.5e-06 25.4 0.0 8.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE37061.1 - 0.00019 21.3 0.0 0.0005 20.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKE37061.1 - 0.0032 16.6 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EKE37061.1 - 0.0043 16.3 0.0 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.22 EKE37061.1 - 0.017 15.4 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter IIGP PF05049.8 EKE37061.1 - 0.025 13.4 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arch_ATPase PF01637.13 EKE37061.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 EKE37061.1 - 0.044 12.6 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EKE37061.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Dynamin family SMC_N PF02463.14 EKE37061.1 - 0.058 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain GTP_EFTU PF00009.22 EKE37061.1 - 0.13 11.6 0.0 0.89 8.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EKE37061.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKE37061.1 - 0.6 10.0 7.7 6 6.7 5.3 2.0 1 1 0 1 1 1 0 AAA domain Metallophos PF00149.23 EKE37062.1 - 0.00022 20.7 1.6 0.00046 19.6 1.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2360 PF10152.4 EKE37062.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase_Tyr PF07714.12 EKE37063.1 - 1.8e-17 63.2 0.1 3.5e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37063.1 - 4.1e-14 52.3 0.0 7.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain VSP PF03302.8 EKE37063.1 - 0.0052 15.4 17.0 0.0052 15.4 11.8 7.8 1 1 4 5 5 5 3 Giardia variant-specific surface protein Endomucin PF07010.7 EKE37063.1 - 0.043 13.1 0.1 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Endomucin DUF63 PF01889.12 EKE37064.1 - 0.0069 16.5 0.3 0.013 15.6 0.2 1.4 1 0 0 1 1 1 1 Membrane protein of unknown function DUF63 DUF2590 PF10761.4 EKE37064.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) Pkinase PF00069.20 EKE37065.1 - 2.1e-35 122.1 0.0 3e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37065.1 - 6.7e-19 67.9 0.0 1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37065.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like TPR_2 PF07719.12 EKE37067.1 - 1.5e-21 74.5 11.9 7.7e-05 22.3 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 EKE37067.1 - 5.3e-19 66.9 25.8 1.4e-05 24.4 0.0 7.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EKE37067.1 - 4.4e-17 61.7 9.0 1.6e-08 34.3 0.1 5.4 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKE37067.1 - 2e-16 59.3 15.2 1.2e-08 34.4 0.6 6.3 4 2 1 6 6 6 3 TPR repeat TPR_7 PF13176.1 EKE37067.1 - 2e-11 42.7 0.9 0.002 17.7 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE37067.1 - 4.7e-11 41.6 19.1 0.00064 19.3 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE37067.1 - 1.7e-09 38.0 0.3 0.0018 18.9 0.0 4.8 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKE37067.1 - 6.5e-06 26.3 0.0 28 5.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE37067.1 - 1.4e-05 25.2 11.5 0.17 12.4 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37067.1 - 4e-05 23.8 2.5 0.22 11.8 0.0 5.1 5 1 2 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EKE37067.1 - 0.0024 17.9 20.9 0.028 14.5 1.8 5.7 3 1 4 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 EKE37067.1 - 0.0043 16.2 0.1 0.033 13.3 0.0 2.3 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 EKE37067.1 - 0.043 13.6 0.1 0.043 13.6 0.0 5.6 8 0 0 8 8 8 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EKE37067.1 - 1.9 7.8 5.8 11 5.3 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR Sel1 PF08238.7 EKE37068.1 - 2.5e-08 34.3 0.8 0.0072 16.9 0.0 4.5 4 0 0 4 4 4 2 Sel1 repeat TPR_8 PF13181.1 EKE37068.1 - 0.00018 21.0 10.2 0.058 13.1 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37068.1 - 0.00053 20.2 7.6 0.056 13.7 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKE37068.1 - 0.0015 18.0 2.8 0.26 10.9 0.2 3.5 2 1 2 4 4 4 1 TPR repeat TPR_14 PF13428.1 EKE37068.1 - 0.0019 18.6 0.0 0.9 10.3 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKE37068.1 - 0.0023 17.7 0.2 16 5.7 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE37068.1 - 0.014 15.8 3.6 0.081 13.4 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKE37068.1 - 0.042 13.4 1.4 14 5.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 EKE37068.1 - 0.05 12.6 0.1 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EKE37068.1 - 0.26 11.4 12.0 4.3 7.5 2.2 4.4 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF912 PF06024.7 EKE37069.1 - 0.002 18.1 0.3 0.0024 17.8 0.2 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EKE37069.1 - 0.0028 17.3 0.1 0.0028 17.3 0.1 1.1 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 EKE37069.1 - 0.0051 16.5 0.7 0.0056 16.3 0.5 1.2 1 0 0 1 1 1 1 TMEM154 protein family OSTMP1 PF09777.4 EKE37069.1 - 0.032 13.3 0.3 0.038 13.1 0.2 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor TraG_N PF07916.6 EKE37069.1 - 0.11 10.8 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region m04gp34like PF12216.3 EKE37069.1 - 0.11 11.7 0.1 0.12 11.7 0.1 1.0 1 0 0 1 1 1 0 Immune evasion protein ODV-E18 PF10717.4 EKE37069.1 - 0.2 11.1 1.6 0.48 9.8 1.1 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 MRAP PF15183.1 EKE37069.1 - 0.89 9.2 4.1 1.4 8.6 2.8 1.5 1 1 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF1201 PF06716.6 EKE37069.1 - 6.8 6.5 9.8 10 6.0 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1201) Vma12 PF11712.3 EKE37070.1 - 3.5e-05 23.5 0.1 6.2e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2897 PF11446.3 EKE37070.1 - 0.0017 18.1 0.2 0.0017 18.1 0.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2897) Zip PF02535.17 EKE37070.1 - 0.02 13.8 0.0 0.028 13.4 0.0 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter IncA PF04156.9 EKE37070.1 - 0.065 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 IncA protein MCM PF00493.18 EKE37071.1 - 6.3e-137 455.8 4.6 4.1e-136 453.1 1.2 2.4 2 1 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 EKE37071.1 - 6.4e-17 61.9 29.2 6.4e-17 61.9 20.2 2.7 2 1 1 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EKE37071.1 - 9.8e-17 61.5 2.7 1.6e-16 60.9 0.1 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKE37071.1 - 2e-10 40.2 0.1 6.2e-08 32.0 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKE37071.1 - 1.3e-07 31.4 0.0 2.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKE37071.1 - 0.00019 21.0 0.0 0.02 14.4 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKE37071.1 - 0.001 18.5 0.0 0.0066 15.9 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Ras PF00071.17 EKE37072.1 - 2.9e-51 173.0 1.2 3.5e-51 172.7 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37072.1 - 1.5e-15 57.7 0.1 2.9e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE37072.1 - 3.7e-14 52.3 0.2 4.5e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE37072.1 - 7.5e-08 32.0 1.4 4e-06 26.3 1.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE37072.1 - 0.00018 20.7 0.2 0.00075 18.7 0.1 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE37072.1 - 0.00023 21.0 0.2 0.0003 20.7 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE37072.1 - 0.001 18.2 0.1 0.0012 18.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE37072.1 - 0.003 17.7 0.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EKE37072.1 - 0.015 14.8 0.9 0.028 13.9 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKE37072.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EKE37072.1 - 0.025 14.0 0.2 0.045 13.2 0.2 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EKE37072.1 - 0.026 14.0 0.5 0.089 12.2 0.4 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Torsin PF06309.6 EKE37072.1 - 0.04 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin PRK PF00485.13 EKE37072.1 - 0.096 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EKE37072.1 - 0.1 12.8 0.2 0.28 11.3 0.1 1.8 2 0 0 2 2 2 0 RNA helicase DUF1280 PF06918.9 EKE37072.1 - 0.11 11.7 3.0 5.9 6.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1280) zf-met PF12874.2 EKE37074.1 - 8.5e-06 25.7 1.4 2.2e-05 24.4 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EKE37074.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PH PF00169.24 EKE37076.1 - 3.6e-15 56.0 0.1 7.6e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKE37076.1 - 4.8e-06 26.7 0.1 1.1e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EKE37076.1 - 0.00012 22.1 0.1 0.00024 21.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1128 PF06569.6 EKE37076.1 - 0.11 12.2 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) FYVE PF01363.16 EKE37077.1 - 7.9e-19 67.3 9.6 1.4e-18 66.5 6.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_C PF02752.17 EKE37077.1 - 0.00073 19.6 0.8 0.33 11.0 0.1 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain FYVE_2 PF02318.11 EKE37077.1 - 0.058 13.2 6.3 0.11 12.3 4.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2H2_6 PF13912.1 EKE37077.1 - 0.11 12.4 7.5 4.8 7.2 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Smr PF01713.16 EKE37078.1 - 2.2e-07 30.9 1.9 4.6e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 Smr domain Metal_resist PF13801.1 EKE37078.1 - 0.021 14.8 0.5 0.035 14.0 0.3 1.3 1 0 0 1 1 1 0 Heavy-metal resistance TMEM210 PF15195.1 EKE37078.1 - 0.039 14.0 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 TMEM210 family Ras PF00071.17 EKE37079.1 - 4.6e-44 149.6 0.1 5.5e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE37079.1 - 6.5e-17 61.3 0.0 8.8e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE37079.1 - 2.3e-16 60.3 0.1 3.6e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EKE37079.1 - 3.5e-07 30.4 0.0 6.6e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EKE37079.1 - 7.2e-06 25.3 0.0 8.4e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE37079.1 - 1.5e-05 24.2 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE37079.1 - 4.3e-05 23.4 0.0 5.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EKE37079.1 - 0.0052 16.8 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EKE37079.1 - 0.0071 15.9 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EKE37079.1 - 0.0072 15.3 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.12 EKE37079.1 - 0.0095 15.4 0.2 3 7.3 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein NACHT PF05729.7 EKE37079.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EKE37079.1 - 0.027 13.9 0.1 0.14 11.6 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EKE37079.1 - 0.039 13.5 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EKE37079.1 - 0.052 13.4 0.1 0.075 12.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EKE37079.1 - 0.06 12.3 0.7 0.087 11.8 0.5 1.3 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EKE37079.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase Sigma54_activat PF00158.21 EKE37079.1 - 0.096 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Paramecium_SA PF01508.11 EKE37079.1 - 0.25 11.5 2.6 0.6 10.3 1.8 1.6 1 0 0 1 1 1 0 Paramecium surface antigen domain CAF-1_p150 PF11600.3 EKE37080.1 - 0.41 9.9 37.6 0.5 9.7 26.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_C6 PF00851.13 EKE37080.1 - 1.6 7.2 12.0 1.9 7.0 8.3 1.0 1 0 0 1 1 1 0 Helper component proteinase Herpes_UL95 PF03038.9 EKE37080.1 - 1.7 7.4 9.1 2 7.2 6.3 1.1 1 0 0 1 1 1 0 UL95 family OEP PF02321.13 EKE37080.1 - 1.7 8.1 8.7 2.2 7.8 6.0 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein AAA_13 PF13166.1 EKE37080.1 - 2.9 6.2 23.4 3.4 6.0 16.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3347 PF11827.3 EKE37080.1 - 3 7.8 20.3 4 7.3 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF2201_N PF13203.1 EKE37080.1 - 7.4 5.6 10.8 8.9 5.3 7.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Orbi_VP5 PF00901.12 EKE37080.1 - 7.6 4.6 21.1 8.9 4.3 14.6 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TMPIT PF07851.8 EKE37080.1 - 7.7 5.4 17.6 10 5.0 12.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Neur_chan_memb PF02932.11 EKE37080.1 - 7.9 6.2 16.2 8.5 6.1 11.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.17 EKE37081.1 - 2.1e-20 72.0 0.1 2.5e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37081.1 - 1.2e-14 54.0 0.0 1.4e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE37081.1 - 1.2e-13 50.7 0.0 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE37081.1 - 0.0034 17.1 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EKE37081.1 - 0.02 14.6 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 DOCK-C2 PF14429.1 EKE37082.1 - 7e-29 100.7 4.4 9.4e-29 100.3 1.8 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EKE37082.1 - 1.2e-06 27.9 0.6 1.2e-06 27.9 0.4 3.2 4 0 0 4 4 4 1 Dedicator of cytokinesis DUF2203 PF09969.4 EKE37083.1 - 0.14 12.3 1.7 0.18 12.0 0.7 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CR6_interact PF10147.4 EKE37083.1 - 1.9 7.7 6.1 3.2 7.0 4.2 1.4 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SH3_9 PF14604.1 EKE37084.1 - 2.5e-16 58.9 1.3 0.00016 21.1 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 EKE37084.1 - 7e-16 57.3 4.7 1.9e-06 27.1 0.0 5.1 5 0 0 5 5 5 3 SH3 domain SH3_2 PF07653.12 EKE37084.1 - 2.7e-13 49.1 0.4 0.0017 17.8 0.0 4.7 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EKE37084.1 - 0.0029 17.7 2.4 0.44 10.7 0.0 3.5 4 0 0 4 4 4 1 Bacterial SH3 domain SH3_6 PF12913.2 EKE37084.1 - 0.0099 15.0 0.0 1 8.6 0.0 3.2 3 0 0 3 3 3 1 SH3 domain of the SH3b1 type SGS PF05002.10 EKE37086.1 - 3.6e-24 84.3 8.8 1.3e-23 82.4 4.7 2.5 2 1 0 2 2 2 1 SGS domain CS PF04969.11 EKE37086.1 - 2e-11 44.2 3.7 3.1e-11 43.6 2.5 1.3 1 0 0 1 1 1 1 CS domain Filamin PF00630.14 EKE37086.1 - 0.054 14.0 0.6 0.096 13.2 0.4 1.5 1 1 0 1 1 1 0 Filamin/ABP280 repeat Invas_SpaK PF03519.9 EKE37086.1 - 0.09 12.6 0.3 0.84 9.5 0.1 2.2 2 0 0 2 2 2 0 Invasion protein B family TLD PF07534.11 EKE37087.1 - 0.074 13.0 0.2 0.091 12.7 0.1 1.2 1 0 0 1 1 1 0 TLD DAGK_acc PF00609.14 EKE37088.1 - 1.2e-29 103.4 0.0 2.4e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.17 EKE37088.1 - 4.5e-12 45.5 53.3 5.5e-07 29.2 8.4 3.5 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.19 EKE37088.1 - 1.9e-11 43.5 0.0 2.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Dynamin_N PF00350.18 EKE37089.1 - 2.4e-06 27.4 0.0 7.3e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin family EF-hand_4 PF12763.2 EKE37089.1 - 0.0013 18.4 0.0 0.0036 17.0 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand AAA_28 PF13521.1 EKE37089.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 EKE37090.1 - 1.7e-141 472.2 10.3 1.9e-141 472.0 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 EKE37092.1 - 3.2e-35 120.9 0.2 5.2e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37092.1 - 8.2e-14 52.1 0.2 1.9e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE37092.1 - 1.8e-11 43.5 0.2 3.2e-11 42.7 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE37092.1 - 0.00019 20.6 0.0 0.00047 19.3 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE37092.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE37092.1 - 0.012 15.1 0.8 0.055 12.9 0.5 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EKE37092.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EKE37092.1 - 0.022 13.4 3.3 2.2 6.8 0.2 2.6 2 1 1 3 3 3 0 G-protein alpha subunit MobB PF03205.9 EKE37092.1 - 0.062 12.9 1.9 0.38 10.4 0.0 2.9 3 1 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_VP8_L4R PF04498.7 EKE37092.1 - 0.11 11.7 1.9 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Poxvirus nucleic acid binding protein VP8/L4R SRPRB PF09439.5 EKE37092.1 - 0.13 11.5 3.2 0.14 11.3 0.0 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF1102 PF06510.6 EKE37093.1 - 0.03 14.1 0.9 0.044 13.5 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1102) Pkinase PF00069.20 EKE37094.1 - 8.5e-24 84.0 0.0 8.5e-24 84.0 0.0 3.7 2 2 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EKE37094.1 - 0.00027 20.0 0.0 0.00061 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF647 PF04884.9 EKE37096.1 - 1.9e-27 96.0 2.1 3.3e-27 95.2 1.5 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Hs1pro-1_N PF07231.7 EKE37096.1 - 0.043 13.4 1.0 1.3 8.5 0.1 2.1 2 0 0 2 2 2 0 Hs1pro-1 N-terminus Beach PF02138.13 EKE37098.1 - 2.7e-91 305.7 2.7 2.7e-91 305.7 1.8 3.1 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 EKE37098.1 - 1.6e-11 43.9 3.2 6.7e-11 41.9 2.2 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EKE37098.1 - 4.2e-06 27.0 0.0 8.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CHRD PF07452.7 EKE37098.1 - 0.13 12.8 0.0 0.69 10.5 0.1 2.1 2 0 0 2 2 2 0 CHRD domain Apolipoprotein PF01442.13 EKE37098.1 - 0.16 11.4 0.3 0.29 10.5 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PQQ_2 PF13360.1 EKE37098.1 - 1 8.7 0.0 1.7 8.0 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain Thioredoxin PF00085.15 EKE37099.1 - 2.9e-09 36.5 0.0 3.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF1340 PF07067.6 EKE37099.1 - 0.024 13.7 0.1 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Thioredoxin_2 PF13098.1 EKE37099.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.6 1 1 1 2 2 2 0 Thioredoxin-like domain Indigoidine_A PF04227.7 EKE37100.1 - 2.6e-115 384.6 4.1 4.1e-115 384.0 2.8 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EKE37100.1 - 1.3e-35 122.9 0.1 5e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase ArsD PF06953.6 EKE37100.1 - 0.00019 21.5 0.3 0.079 13.1 0.1 3.0 3 0 0 3 3 3 2 Arsenical resistance operon trans-acting repressor ArsD Phos_pyr_kin PF08543.7 EKE37100.1 - 0.0098 15.1 0.0 0.027 13.6 0.0 1.8 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Hydrolase_3 PF08282.7 EKE37101.1 - 6.4e-43 147.1 9.7 1.8e-42 145.6 6.7 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKE37101.1 - 8.9e-09 35.0 1.0 4.8e-08 32.6 0.7 1.9 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKE37101.1 - 3e-07 30.8 1.5 1.1e-05 25.6 0.2 3.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE37101.1 - 0.00053 20.4 0.3 0.0039 17.6 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EKE37101.1 - 0.0022 17.1 1.2 0.024 13.8 0.0 2.4 1 1 0 2 2 2 1 Putative Phosphatase DUF2277 PF10041.4 EKE37101.1 - 0.034 14.0 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) RabGAP-TBC PF00566.13 EKE37103.1 - 9.8e-30 103.6 1.4 2.5e-29 102.3 1.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 EKE37103.1 - 3.6e-27 94.5 1.2 3.8e-11 43.1 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE37103.1 - 2.9e-23 80.4 0.5 0.00011 21.7 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EKE37103.1 - 5.8e-21 74.4 0.8 1.8e-08 34.6 0.0 5.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE37103.1 - 3.7e-20 71.4 0.4 2.9e-09 36.8 0.1 5.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE37103.1 - 1.1e-17 62.3 0.8 0.014 15.5 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat ADH_N PF08240.7 EKE37104.1 - 0.029 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-UBR PF02207.15 EKE37107.1 - 9.2e-15 54.1 20.7 9.2e-15 54.1 14.4 3.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) TPR_MLP1_2 PF07926.7 EKE37109.1 - 0.0003 20.5 10.4 0.00041 20.0 7.2 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EKE37109.1 - 0.0051 15.8 8.3 0.0063 15.4 5.7 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FliD_C PF07195.7 EKE37109.1 - 0.034 13.4 2.4 0.049 12.9 1.7 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus AAA_13 PF13166.1 EKE37109.1 - 0.038 12.4 11.5 0.046 12.1 7.9 1.0 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 EKE37109.1 - 0.89 9.3 5.1 1.3 8.7 3.5 1.3 1 0 0 1 1 1 0 Laminin Domain II V_ATPase_I PF01496.14 EKE37109.1 - 1.7 6.3 8.9 2.2 6.0 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup88 PF10168.4 EKE37109.1 - 1.8 6.2 11.0 2.1 6.1 7.6 1.0 1 0 0 1 1 1 0 Nuclear pore component Fib_alpha PF08702.5 EKE37109.1 - 3.3 7.8 9.0 2.4 8.2 2.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LCAT PF02450.10 EKE37110.1 - 2.8e-28 98.9 0.1 3.2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EKE37110.1 - 6.6e-06 25.8 0.0 3.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 EKE37110.1 - 0.00086 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 EKE37110.1 - 0.054 12.5 0.4 0.12 11.4 0.3 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Surf_Ag_VNR PF07244.10 EKE37110.1 - 0.072 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Surface antigen variable number repeat Abhydrolase_6 PF12697.2 EKE37110.1 - 0.079 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE37110.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase_Tyr PF07714.12 EKE37111.1 - 1.6e-30 106.0 0.0 3.4e-30 104.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37111.1 - 1e-25 90.3 0.2 4.5e-25 88.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain VSP PF03302.8 EKE37111.1 - 0.053 12.1 122.7 0.034 12.8 25.1 5.2 1 1 4 5 5 5 0 Giardia variant-specific surface protein COX1 PF00115.15 EKE37111.1 - 0.34 9.4 1.1 0.53 8.8 0.8 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Ribosomal_L36e PF01158.13 EKE37113.1 - 2.7e-26 91.3 3.3 3.3e-26 91.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e DUF531 PF04407.7 EKE37113.1 - 0.012 15.5 0.4 2.3 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF531) Propeptide_C1 PF08127.8 EKE37113.1 - 0.045 13.3 0.4 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C1 propeptide CLTH PF10607.4 EKE37113.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.4 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain TetR PF13972.1 EKE37114.1 - 0.025 13.9 0.5 3.2 7.1 0.0 2.8 3 0 0 3 3 3 0 Bacterial transcriptional repressor DOCK-C2 PF14429.1 EKE37115.1 - 2.2e-44 151.3 0.3 5.4e-44 150.0 0.2 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Turandot PF07240.6 EKE37116.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot COPIIcoated_ERV PF07970.7 EKE37117.1 - 1.6e-54 184.8 1.0 1.6e-54 184.8 0.7 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EKE37117.1 - 6.4e-25 86.9 0.1 1.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Stc1 PF12898.2 EKE37117.1 - 0.12 12.4 4.8 0.23 11.5 3.3 1.5 1 0 0 1 1 1 0 Stc1 domain Adeno_E3B PF03376.9 EKE37117.1 - 1.7 8.5 7.3 0.8 9.6 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3B protein DUF4094 PF13334.1 EKE37118.1 - 0.00011 22.5 0.3 0.00011 22.5 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) Pex19 PF04614.7 EKE37118.1 - 0.049 13.2 0.2 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Pex19 protein family CARD PF00619.16 EKE37118.1 - 0.078 12.8 0.4 0.24 11.2 0.2 2.0 2 0 0 2 2 2 0 Caspase recruitment domain GrpE PF01025.14 EKE37118.1 - 0.12 11.9 7.4 0.051 13.1 2.0 2.4 1 1 1 2 2 2 0 GrpE Mt_ATP-synt_B PF05405.9 EKE37118.1 - 2 7.8 9.3 4.7 6.6 1.1 3.1 2 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CENP-H PF05837.7 EKE37118.1 - 7.6 6.7 13.7 9.7 6.4 3.1 2.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TSC22 PF01166.13 EKE37119.1 - 0.0014 18.5 3.8 0.008 16.1 2.0 2.9 1 1 0 1 1 1 1 TSC-22/dip/bun family HAP1_N PF04849.8 EKE37119.1 - 0.0016 17.4 12.5 0.0016 17.4 8.7 2.6 3 0 0 3 3 3 1 HAP1 N-terminal conserved region bZIP_1 PF00170.16 EKE37119.1 - 0.0053 16.6 8.4 0.0053 16.6 5.8 2.9 1 1 1 2 2 2 1 bZIP transcription factor DUF4407 PF14362.1 EKE37119.1 - 0.14 11.1 5.9 0.29 10.0 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.11 EKE37119.1 - 0.56 8.7 5.8 0.9 8.0 4.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein PMC2NT PF08066.7 EKE37119.1 - 2.3 8.5 7.3 0.36 11.1 0.9 2.9 2 1 1 3 3 3 0 PMC2NT (NUC016) domain FTCD_C PF04961.7 EKE37119.1 - 4.8 6.5 6.2 2.5 7.4 1.6 2.4 2 1 1 3 3 3 0 Formiminotransferase-cyclodeaminase Tetraspannin PF00335.15 EKE37120.1 - 0.00069 18.9 23.6 0.0043 16.3 16.5 2.0 1 1 0 1 1 1 1 Tetraspanin family IncA PF04156.9 EKE37120.1 - 0.03 13.8 0.4 0.03 13.8 0.3 3.2 3 1 0 3 3 3 0 IncA protein CRPA PF05745.6 EKE37120.1 - 0.12 12.1 11.1 0.41 10.4 0.5 3.2 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Cytochrom_B_C PF00032.12 EKE37120.1 - 2.4 8.4 10.8 0.89 9.8 4.1 2.3 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Ninjurin PF04923.7 EKE37120.1 - 7.6 6.3 9.3 0.96 9.2 0.3 2.7 3 0 0 3 3 3 0 Ninjurin Ribosomal_S13 PF00416.17 EKE37121.1 - 5.8e-35 119.9 0.3 6.8e-35 119.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 SurA_N_2 PF13623.1 EKE37122.1 - 0.0077 16.2 0.3 0.011 15.7 0.2 1.2 1 0 0 1 1 1 1 SurA N-terminal domain DUF2570 PF10828.3 EKE37122.1 - 0.013 15.1 0.2 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Mlf1IP PF10248.4 EKE37122.1 - 0.029 13.9 1.0 0.039 13.5 0.7 1.3 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF4038 PF13204.1 EKE37123.1 - 0.0011 18.3 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Chromo PF00385.19 EKE37124.1 - 2.5e-07 30.2 3.8 5e-05 22.8 0.1 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EKE37124.1 - 0.00021 21.0 0.1 0.0038 17.0 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LCAT PF02450.10 EKE37125.1 - 6.3e-39 134.0 1.5 3.3e-36 125.1 0.1 2.2 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EKE37125.1 - 3.4e-07 30.1 0.0 7.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EKE37125.1 - 5e-06 26.5 0.0 2.6e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE37125.1 - 2.6e-05 23.9 0.0 6.8e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 EKE37125.1 - 8.9e-05 21.8 0.0 0.00019 20.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 EKE37125.1 - 0.00017 20.5 0.0 0.16 10.7 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme DUF915 PF06028.6 EKE37125.1 - 0.00041 19.5 0.2 0.017 14.2 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 EKE37125.1 - 0.00069 19.3 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EKE37125.1 - 0.00093 18.8 0.0 0.02 14.5 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Lipase_3 PF01764.20 EKE37125.1 - 0.0022 17.6 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) DUF2305 PF10230.4 EKE37125.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Cutinase PF01083.17 EKE37125.1 - 0.076 12.7 0.0 0.52 10.0 0.0 2.3 3 0 0 3 3 3 0 Cutinase DUF3577 PF12101.3 EKE37125.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) Esterase PF00756.15 EKE37125.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Methuselah_N PF06652.7 EKE37125.1 - 0.093 12.2 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Methuselah N-terminus DUF900 PF05990.7 EKE37125.1 - 0.099 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) HAD PF12710.2 EKE37126.1 - 8.6e-17 61.9 0.1 2.1e-16 60.6 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE37126.1 - 8.7e-14 52.4 0.0 2.9e-13 50.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE37126.1 - 5.4e-12 45.4 0.5 5.4e-12 45.4 0.4 2.3 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EKE37126.1 - 8.4e-11 41.3 5.3 8.6e-11 41.3 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase DUF3482 PF11981.3 EKE37127.1 - 0.05 12.8 1.6 0.09 11.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Myb_DNA-bind_6 PF13921.1 EKE37128.1 - 1.4e-05 25.1 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKE37128.1 - 2.9e-05 24.0 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF972 PF06156.8 EKE37128.1 - 6.7 7.0 8.2 0.55 10.6 1.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_S17e PF00833.13 EKE37129.1 - 4.2e-56 187.9 1.2 4.5e-56 187.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal S17 PSS PF03034.10 EKE37130.1 - 1.1e-93 313.6 18.7 1.1e-93 313.6 13.0 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase 1-cysPrx_C PF10417.4 EKE37131.1 - 0.0023 17.5 0.1 0.0049 16.4 0.1 1.6 1 1 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF2716 PF10898.3 EKE37131.1 - 0.009 16.0 0.0 0.009 16.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2716) Ras PF00071.17 EKE37132.1 - 1.7e-20 73.0 0.1 2.1e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37132.1 - 7.5e-12 45.7 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKE37132.1 - 3.2e-06 26.4 0.1 3.9e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EKE37132.1 - 0.00018 20.7 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE37132.1 - 0.00029 20.7 0.0 0.00044 20.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE37132.1 - 0.0004 19.8 0.0 0.0046 16.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EKE37132.1 - 0.00046 20.9 0.1 0.002 18.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKE37132.1 - 0.0083 16.0 0.4 0.028 14.3 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EKE37132.1 - 0.0085 16.4 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EKE37132.1 - 0.012 14.8 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EKE37132.1 - 0.019 15.0 0.0 0.083 13.0 0.0 1.9 1 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 EKE37132.1 - 0.054 12.7 0.2 0.17 11.0 0.1 1.9 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EKE37132.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKE37132.1 - 0.068 13.1 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKE37132.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 EKE37132.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IncA PF04156.9 EKE37133.1 - 0.5 9.9 4.2 0.2 11.2 1.0 1.6 1 1 0 1 1 1 0 IncA protein AKNA PF12443.3 EKE37133.1 - 1.5 8.8 9.8 14 5.7 0.9 3.4 1 1 2 3 3 3 0 AT-hook-containing transcription factor Nic96 PF04097.9 EKE37134.1 - 2.3e-06 26.0 4.8 6e-05 21.3 0.4 2.3 2 0 0 2 2 2 2 Nup93/Nic96 DUF2240 PF09999.4 EKE37134.1 - 0.089 12.2 0.1 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Far-17a_AIG1 PF04750.9 EKE37135.1 - 2.9e-09 36.4 14.2 3.9e-09 35.9 9.8 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2130 PF09903.4 EKE37135.1 - 0.1 11.3 0.2 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) IBR PF01485.16 EKE37136.1 - 1.8e-11 43.7 11.4 2.1e-11 43.5 7.9 1.1 1 0 0 1 1 1 1 IBR domain zf-RING_4 PF14570.1 EKE37136.1 - 0.0079 15.7 13.8 0.1 12.1 9.9 2.0 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain DNA_ligase_ZBD PF03119.11 EKE37136.1 - 0.076 12.7 1.9 0.14 11.8 1.3 1.6 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C3HC4_3 PF13920.1 EKE37136.1 - 0.6 9.8 12.6 0.38 10.4 0.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE37136.1 - 1.3 8.7 14.0 4.8 6.9 9.4 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE37136.1 - 2.4 7.9 13.0 6.8 6.5 8.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-UDP PF14569.1 EKE37136.1 - 3.5 7.4 6.4 1.8 8.3 0.5 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 EKE37136.1 - 7.3 6.5 13.4 1.5e+02 2.3 0.4 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EKE37137.1 - 1.3e-06 28.1 6.8 1.9e-06 27.6 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE37137.1 - 2e-06 27.6 7.7 3.7e-06 26.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE37137.1 - 2.4e-05 23.9 4.6 5.1e-05 22.8 3.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE37137.1 - 0.00019 21.2 8.9 0.002 17.9 6.4 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EKE37137.1 - 0.00031 20.3 9.1 0.0006 19.4 6.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.6 EKE37137.1 - 0.0011 18.7 2.1 0.0012 18.5 1.5 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.1 EKE37137.1 - 0.0016 18.0 7.2 0.0036 16.9 5.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKE37137.1 - 0.0088 15.7 5.8 0.017 14.8 3.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EKE37137.1 - 0.022 14.3 4.4 0.044 13.3 3.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EKE37137.1 - 0.055 13.2 1.3 4 7.3 0.2 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-CSL PF05207.8 EKE37137.1 - 0.25 10.8 2.7 2 7.9 1.3 2.1 1 1 1 2 2 2 0 CSL zinc finger zf-rbx1 PF12678.2 EKE37137.1 - 0.54 10.4 6.3 1.3 9.2 3.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger IBR PF01485.16 EKE37137.1 - 0.73 9.7 13.2 2.7 7.9 4.0 2.7 1 1 1 2 2 2 0 IBR domain FYVE PF01363.16 EKE37137.1 - 1.6 8.6 7.4 4.1 7.3 5.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 EKE37137.1 - 2.8 7.5 7.0 15 5.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EKE37137.1 - 5.7 6.9 9.7 16 5.5 5.8 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain DUF4293 PF14126.1 EKE37139.1 - 0.0034 17.3 0.8 0.0047 16.8 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4293) Orbi_NS3 PF01616.11 EKE37139.1 - 0.072 12.0 3.8 0.46 9.4 0.5 2.1 2 0 0 2 2 2 0 Orbivirus NS3 DUF4064 PF13273.1 EKE37139.1 - 0.55 10.3 7.1 0.037 14.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) TMEM154 PF15102.1 EKE37139.1 - 0.71 9.5 11.0 1.3 8.6 7.6 1.4 1 1 0 1 1 1 0 TMEM154 protein family Tetraspannin PF00335.15 EKE37139.1 - 4.2 6.5 9.6 1.1 8.4 4.4 1.6 1 1 1 2 2 2 0 Tetraspanin family Bacteriocin_II PF01721.13 EKE37140.1 - 0.24 10.9 2.1 0.28 10.7 1.5 1.2 1 0 0 1 1 1 0 Class II bacteriocin NHL PF01436.16 EKE37143.1 - 9.6e-16 56.8 8.1 1.1e-06 28.2 0.0 5.5 6 0 0 6 6 6 3 NHL repeat SGL PF08450.7 EKE37143.1 - 3e-05 23.5 0.1 0.019 14.3 0.0 2.5 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region BAH PF01426.13 EKE37143.1 - 0.025 14.3 0.2 0.083 12.6 0.0 2.0 2 0 0 2 2 2 0 BAH domain Suppressor_APC PF11414.3 EKE37143.1 - 0.093 12.5 2.1 0.17 11.6 1.4 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein STAT_alpha PF01017.15 EKE37143.1 - 0.11 12.2 7.6 0.15 11.7 5.3 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Oxysterol_BP PF01237.13 EKE37144.1 - 5.4e-74 248.8 1.6 8.8e-74 248.1 1.1 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein HUN PF08729.5 EKE37146.1 - 3.3e-07 30.0 1.5 1.5e-06 27.9 0.0 3.1 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Sod_Fe_C PF02777.13 EKE37146.1 - 0.12 12.2 3.2 3 7.7 0.1 2.9 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain EF-hand_7 PF13499.1 EKE37147.1 - 3.8e-17 62.1 4.3 1.4e-10 41.1 3.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE37147.1 - 2e-16 58.3 7.0 1.8e-05 24.2 0.8 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 EKE37147.1 - 4.6e-16 56.8 12.5 9.1e-06 24.6 1.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EKE37147.1 - 2.7e-13 49.2 10.1 1.3e-06 27.8 1.0 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 EKE37147.1 - 2.1e-05 24.3 0.3 0.06 13.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EKE37147.1 - 0.00013 21.1 8.7 0.66 9.4 0.1 3.6 3 0 0 3 3 3 3 EF hand DUF1456 PF07308.8 EKE37147.1 - 0.0052 16.7 1.6 0.0085 16.1 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1456) Adenine_glyco PF03352.8 EKE37147.1 - 0.0088 15.5 0.1 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase SPARC_Ca_bdg PF10591.4 EKE37147.1 - 0.018 15.0 1.7 0.27 11.2 0.5 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKE37147.1 - 0.077 12.7 1.3 0.17 11.6 0.5 1.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Aminotran_1_2 PF00155.16 EKE37148.1 - 2.9e-10 39.6 0.0 3.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKE37148.1 - 0.08 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_C25 PF01364.13 EKE37148.1 - 0.089 11.7 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 Cullin PF00888.17 EKE37149.1 - 7.5e-73 246.0 42.9 1.1e-72 245.5 29.8 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EKE37149.1 - 5.4e-22 77.3 4.7 5.4e-22 77.3 3.3 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Pkinase PF00069.20 EKE37150.1 - 1.6e-70 237.2 1.2 2.1e-70 236.8 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37150.1 - 5.2e-32 110.9 0.3 7.2e-32 110.4 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37150.1 - 7e-07 28.4 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FHA PF00498.21 EKE37150.1 - 6.3e-05 23.0 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EKE37150.1 - 0.00028 20.0 0.0 0.00051 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EKE37150.1 - 0.0061 16.1 0.4 0.14 11.6 0.0 2.3 1 1 1 2 2 2 1 Choline/ethanolamine kinase MoaE PF02391.12 EKE37150.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 MoaE protein YrbL-PhoP_reg PF10707.4 EKE37150.1 - 0.058 12.7 0.3 0.16 11.2 0.2 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4661 PF15576.1 EKE37151.1 - 1.3 8.5 5.7 0.85 9.2 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) TMC PF07810.8 EKE37152.1 - 0.00051 20.4 0.4 0.00051 20.4 0.3 3.1 3 1 1 4 4 4 1 TMC domain Baculo_11_kDa PF06143.6 EKE37152.1 - 0.022 14.1 0.7 0.022 14.1 0.5 3.0 3 1 1 4 4 4 0 Baculovirus 11 kDa family Anoctamin PF04547.7 EKE37152.1 - 1.1 7.8 30.6 28 3.1 21.2 2.4 1 1 0 1 1 1 0 Calcium-activated chloride channel RabGAP-TBC PF00566.13 EKE37153.1 - 1.8e-15 56.9 4.8 3.1e-15 56.2 3.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-RING_5 PF14634.1 EKE37155.1 - 9.8e-08 31.6 6.9 2.9e-07 30.1 4.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKE37155.1 - 1.7e-07 30.9 5.3 1.7e-07 30.9 3.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE37155.1 - 0.00046 20.1 5.5 0.00046 20.1 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKE37155.1 - 0.012 15.7 4.8 0.042 13.9 3.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EKE37155.1 - 0.12 12.1 1.5 0.46 10.3 1.0 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_1 PF14446.1 EKE37155.1 - 0.33 10.7 4.7 0.27 10.9 0.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EKE37155.1 - 0.38 10.4 5.6 1.4 8.6 3.9 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 EKE37155.1 - 0.73 9.5 15.1 0.022 14.3 5.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cys_rich_CPXG PF14255.1 EKE37155.1 - 1.2 9.0 6.4 6.5 6.6 0.1 3.2 3 0 0 3 3 3 0 Cysteine-rich CPXCG PHD PF00628.24 EKE37155.1 - 4.8 6.9 8.4 2.1 8.1 3.5 2.2 2 0 0 2 2 2 0 PHD-finger Taeniidae_ag PF05596.6 EKE37156.1 - 0.072 12.9 0.1 0.42 10.4 0.0 2.4 1 1 1 2 2 2 0 Taeniidae antigen DUF3458 PF11940.3 EKE37156.1 - 0.076 11.8 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) WW PF00397.21 EKE37157.1 - 7.6e-08 32.0 1.2 1.4e-07 31.2 0.9 1.5 1 0 0 1 1 1 1 WW domain AAA PF00004.24 EKE37158.1 - 1.6e-46 157.7 0.0 1.1e-39 135.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKE37158.1 - 3.3e-08 33.7 0.5 0.014 15.5 0.0 4.1 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.7 EKE37158.1 - 6.8e-07 28.5 0.0 0.00019 20.5 0.0 3.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EKE37158.1 - 1.1e-06 28.5 0.0 0.0015 18.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKE37158.1 - 1.6e-05 24.9 0.1 0.014 15.4 0.0 3.3 2 2 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 EKE37158.1 - 2.1e-05 24.2 0.0 0.34 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EKE37158.1 - 8.4e-05 22.7 0.0 0.17 12.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.7 EKE37158.1 - 0.0001 22.0 0.1 1.7 8.3 0.0 3.7 4 0 0 4 4 4 1 NACHT domain IstB_IS21 PF01695.12 EKE37158.1 - 0.00021 20.7 0.0 0.62 9.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EKE37158.1 - 0.00065 20.5 0.0 0.26 12.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKE37158.1 - 0.00076 19.3 0.0 0.065 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EKE37158.1 - 0.0012 18.7 0.0 0.29 11.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EKE37158.1 - 0.006 16.2 0.0 3.3 7.5 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain TIP49 PF06068.8 EKE37158.1 - 0.012 14.3 0.0 0.28 9.8 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus Mg_chelatase PF01078.16 EKE37158.1 - 0.015 14.4 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EKE37158.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 EKE37158.1 - 0.023 14.7 0.0 3.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EKE37158.1 - 0.027 13.9 0.0 0.76 9.2 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 EKE37158.1 - 0.029 13.7 0.0 0.095 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 EKE37158.1 - 0.038 13.9 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EKE37158.1 - 0.038 14.2 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EKE37158.1 - 0.044 12.7 0.0 2.1 7.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Miro PF08477.8 EKE37158.1 - 0.069 13.6 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 EKE37158.1 - 0.079 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EKE37158.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EKE37158.1 - 0.084 11.5 0.1 7.2 5.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EKE37158.1 - 0.085 12.5 0.0 2.2 7.9 0.0 2.7 2 1 0 2 2 2 0 NTPase UPF0236 PF06782.6 EKE37158.1 - 0.089 11.1 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) PHB_depo_C PF06850.6 EKE37159.1 - 0.15 11.2 0.4 0.24 10.5 0.3 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus LRR_5 PF13306.1 EKE37160.1 - 2.7e-75 250.2 49.5 1.2e-33 115.5 7.1 4.0 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37160.1 - 1.1e-24 85.9 16.4 5.8e-07 29.1 0.8 6.3 2 2 4 6 6 6 6 Leucine rich repeat GP41 PF00517.12 EKE37161.1 - 0.57 9.7 4.3 0.16 11.5 0.8 1.7 2 0 0 2 2 2 0 Retroviral envelope protein Peptidase_U57 PF05582.7 EKE37162.1 - 0.021 13.8 0.1 0.042 12.8 0.0 1.6 2 0 0 2 2 2 0 YabG peptidase U57 Dynamin_M PF01031.15 EKE37163.1 - 3.5e-86 288.6 1.1 6.2e-86 287.8 0.8 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EKE37163.1 - 1.2e-47 161.8 0.0 3.7e-47 160.2 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EKE37163.1 - 4.1e-26 90.7 4.2 4.1e-26 90.7 2.9 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EKE37163.1 - 6.7e-05 22.8 0.7 0.00057 19.8 0.0 2.8 2 2 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EKE37163.1 - 0.00021 21.7 0.6 0.026 15.0 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein Baculo_p74 PF04583.7 EKE37163.1 - 0.0062 15.7 0.4 0.025 13.7 0.0 2.2 3 0 0 3 3 3 1 Baculoviridae p74 conserved region DUF2749 PF10907.3 EKE37163.1 - 0.096 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Glyco_hydro_31 PF01055.21 EKE37166.1 - 2.3e-132 441.9 12.2 3e-132 441.5 8.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKE37166.1 - 9.5e-06 25.3 2.2 1.7e-05 24.5 0.2 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF1039 PF06287.6 EKE37167.1 - 0.19 11.6 1.7 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) Uds1 PF15456.1 EKE37167.1 - 9.2 6.2 33.5 0.22 11.5 6.8 2.6 2 0 0 2 2 2 0 Up-regulated During Septation Calpain_III PF01067.17 EKE37168.1 - 9.9e-42 142.0 0.9 1.1e-14 54.3 0.0 3.6 3 1 0 3 3 3 3 Calpain large subunit, domain III Pkinase PF00069.20 EKE37169.1 - 7.9e-58 195.6 0.0 1.4e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ras PF00071.17 EKE37169.1 - 1.8e-55 186.7 0.4 3.1e-55 185.9 0.3 1.4 1 0 0 1 1 1 1 Ras family Pkinase_Tyr PF07714.12 EKE37169.1 - 1.3e-42 145.6 0.0 2.1e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Miro PF08477.8 EKE37169.1 - 1.3e-15 57.9 0.0 3.8e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE37169.1 - 2.9e-13 49.4 0.1 5.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Kinase-like PF14531.1 EKE37169.1 - 3.8e-05 22.8 0.0 6.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EKE37169.1 - 0.0029 16.4 0.0 0.0061 15.4 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EKE37169.1 - 0.019 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MMR_HSR1 PF01926.18 EKE37169.1 - 0.033 14.1 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M8 PF01457.11 EKE37170.1 - 2.9e-70 237.0 3.4 4e-70 236.6 2.4 1.1 1 0 0 1 1 1 1 Leishmanolysin Topoisom_bac PF01131.15 EKE37171.1 - 3.7e-101 338.8 0.0 4.7e-101 338.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EKE37171.1 - 7.7e-15 54.7 0.0 2.3e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AbfB PF05270.8 EKE37171.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) PRD PF00874.15 EKE37171.1 - 0.068 13.2 0.4 0.24 11.5 0.2 1.9 1 0 0 1 1 1 0 PRD domain LRR_4 PF12799.2 EKE37172.1 - 1.7e-17 62.5 23.1 0.0013 18.3 0.4 10.3 6 3 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EKE37172.1 - 1.2e-14 52.6 11.7 0.94 9.7 0.0 13.4 14 0 0 14 14 14 3 Leucine Rich repeat LRR_8 PF13855.1 EKE37172.1 - 1.2e-10 40.9 22.1 0.016 14.9 0.7 7.9 5 1 4 9 9 9 7 Leucine rich repeat F-box PF00646.28 EKE37172.1 - 7.2e-08 31.9 0.1 3.1e-07 29.8 0.0 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKE37172.1 - 2.7e-05 23.8 0.0 9.1e-05 22.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EKE37172.1 - 8.2e-05 22.1 21.0 10 6.6 0.1 10.2 10 2 0 10 10 10 1 Leucine Rich Repeat LRR_7 PF13504.1 EKE37172.1 - 0.032 14.3 15.6 13 6.4 0.0 9.8 13 0 0 13 13 13 0 Leucine rich repeat Thioredoxin PF00085.15 EKE37173.1 - 5.4e-31 106.3 0.0 6.8e-31 106.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE37173.1 - 4.4e-09 36.5 0.0 2.9e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EKE37173.1 - 4.3e-08 32.7 0.0 5.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKE37173.1 - 4.3e-07 29.9 0.0 5.4e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 EKE37173.1 - 0.00013 21.4 0.2 0.0054 16.2 0.1 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EKE37173.1 - 0.00053 19.9 0.0 0.00081 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EKE37173.1 - 0.0039 16.8 0.3 0.079 12.6 0.1 2.1 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EKE37173.1 - 0.0082 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.6 EKE37173.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 EKE37173.1 - 0.045 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_6 PF13848.1 EKE37173.1 - 0.057 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.15 EKE37173.1 - 0.16 11.4 0.1 6.3 6.3 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain ATP_bind_1 PF03029.12 EKE37174.1 - 3.7e-77 259.0 0.3 4.2e-77 258.8 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EKE37174.1 - 2.4e-05 25.1 0.1 5.4e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EKE37174.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain TRADD_N PF09034.5 EKE37174.1 - 0.0014 18.5 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 TRADD, N-terminal domain AAA_14 PF13173.1 EKE37174.1 - 0.013 15.3 0.1 0.032 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EKE37174.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKE37174.1 - 0.021 15.1 0.0 0.051 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKE37174.1 - 0.029 14.5 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Gtr1_RagA PF04670.7 EKE37174.1 - 0.065 12.3 0.9 12 4.9 0.1 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EKE37174.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_PrkA PF08298.6 EKE37174.1 - 0.078 11.6 0.0 0.23 10.1 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain AAA_10 PF12846.2 EKE37174.1 - 0.089 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 EKE37174.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EKE37174.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EKE37174.1 - 0.14 12.1 0.0 0.58 10.1 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EKE37174.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain Ribosomal_60s PF00428.14 EKE37175.1 - 7.6e-14 51.8 11.9 9.3e-14 51.5 8.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 EKE37175.1 - 0.03 13.9 1.1 0.04 13.5 0.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region AF1Q PF15017.1 EKE37175.1 - 0.037 13.9 0.3 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator DUF2798 PF11391.3 EKE37175.1 - 0.039 13.7 0.6 0.056 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Senescence_reg PF04520.8 EKE37175.1 - 0.068 13.6 0.0 0.076 13.5 0.0 1.1 1 0 0 1 1 1 0 Senescence regulator Ribosomal_60s PF00428.14 EKE37176.1 - 1e-18 67.4 8.4 1.3e-18 67.1 5.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Bot1p PF12298.3 EKE37176.1 - 0.014 15.3 2.4 0.016 15.1 1.7 1.0 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein AF1Q PF15017.1 EKE37176.1 - 0.016 15.1 1.2 0.024 14.5 0.8 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Myc_N PF01056.13 EKE37176.1 - 0.046 12.8 0.7 0.046 12.8 0.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region SHS2_FTSA PF02491.15 EKE37176.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Pex24p PF06398.6 EKE37177.1 - 0.44 9.2 6.2 0.095 11.4 1.3 1.8 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin VSP PF03302.8 EKE37179.1 - 0.00042 19.0 67.3 0.046 12.3 21.7 3.3 1 1 0 2 2 2 2 Giardia variant-specific surface protein DUF3595 PF12166.3 EKE37181.1 - 0.54 9.0 4.4 5.7 5.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) PI3K_C2 PF00792.19 EKE37182.1 - 2.9e-12 46.5 0.1 4.9e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 EKE37182.1 - 2.1e-10 40.4 0.0 5.7e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3Ka PF00613.15 EKE37182.1 - 0.0041 16.3 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Sec7 PF01369.15 EKE37184.1 - 3.5e-28 98.5 7.2 8.9e-28 97.2 4.3 2.3 2 0 0 2 2 2 1 Sec7 domain Pkinase PF00069.20 EKE37185.1 - 7.8e-66 221.8 0.0 1e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37185.1 - 3.8e-43 147.4 0.0 5.5e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE37185.1 - 1.3e-14 54.2 0.0 5.4e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 EKE37185.1 - 1.2e-08 34.7 0.0 2.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PBD PF00786.23 EKE37185.1 - 2.5e-08 34.2 0.0 5.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EKE37185.1 - 5.5e-05 22.2 0.1 0.0037 16.2 0.0 2.3 1 1 0 2 2 2 1 Kinase-like PH_11 PF15413.1 EKE37185.1 - 0.0016 18.7 1.9 0.013 15.7 0.2 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain Peptidase_C5 PF00770.13 EKE37185.1 - 0.018 14.5 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Adenovirus endoprotease PH_8 PF15409.1 EKE37185.1 - 0.025 14.6 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain GatB_Yqey PF02637.13 EKE37187.1 - 0.013 15.2 0.2 0.022 14.4 0.1 1.3 1 1 0 1 1 1 0 GatB domain DUF167 PF02594.11 EKE37187.1 - 0.02 14.8 0.0 5 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 OB_NTP_bind PF07717.11 EKE37189.1 - 9.5e-27 93.0 0.1 2.4e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKE37189.1 - 1.7e-23 82.5 0.1 5.8e-23 80.8 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKE37189.1 - 5.8e-11 42.1 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE37189.1 - 4.3e-07 29.5 0.1 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EKE37189.1 - 1e-05 24.5 0.0 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EKE37189.1 - 2.7e-05 24.3 0.1 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EKE37189.1 - 0.03 14.2 0.2 0.79 9.6 0.1 3.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EKE37189.1 - 0.031 13.5 0.0 0.093 11.9 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EKE37189.1 - 0.035 14.4 0.4 0.035 14.4 0.2 3.4 1 1 2 3 3 1 0 AAA domain AAA_19 PF13245.1 EKE37189.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EKE37189.1 - 0.19 11.2 0.0 0.48 9.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EKE37189.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.7 1 1 1 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EKE37189.1 - 3.2 7.1 7.0 0.57 9.6 0.1 2.8 2 1 1 3 3 3 0 FtsK/SpoIIIE family DUF3753 PF12575.3 EKE37190.1 - 0.31 10.8 2.5 2.9 7.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) XPG_N PF00752.12 EKE37191.1 - 2.5e-28 98.2 0.0 7.3e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EKE37191.1 - 1.9e-26 91.9 0.2 4.9e-26 90.6 0.2 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EKE37191.1 - 1.1e-07 32.0 2.1 4.1e-07 30.1 0.0 2.8 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 EKE37191.1 - 0.0006 19.6 0.2 0.056 13.3 0.0 3.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif 5_3_exonuc_N PF02739.11 EKE37191.1 - 0.00099 18.5 0.0 0.0098 15.2 0.0 2.3 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain PhoU PF01895.14 EKE37191.1 - 0.094 13.1 1.1 0.16 12.4 0.2 1.8 2 0 0 2 2 2 0 PhoU domain IDEAL PF08858.5 EKE37191.1 - 0.18 11.3 3.5 0.51 9.8 2.4 1.7 1 0 0 1 1 1 0 IDEAL domain CSTF2_hinge PF14327.1 EKE37191.1 - 0.19 11.8 1.7 0.56 10.3 1.2 1.8 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 HemY_N PF07219.8 EKE37191.1 - 0.27 10.7 2.4 0.61 9.6 1.7 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DUF106 PF01956.11 EKE37191.1 - 2.8 7.4 8.3 0.5 9.8 2.7 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF106 Sas10 PF09368.5 EKE37192.1 - 7.9e-07 29.1 8.3 3.6e-06 27.0 5.8 2.2 1 0 0 1 1 1 1 Sas10 C-terminal domain Ribosomal_S8e PF01201.17 EKE37193.1 - 3.7e-37 127.4 3.0 2.4e-36 124.8 2.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF4005 PF13178.1 EKE37193.1 - 0.089 13.0 0.4 0.16 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) Whirly PF08536.6 EKE37194.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Whirly transcription factor Shisa PF13908.1 EKE37194.1 - 1.1 9.3 7.4 1.6 8.8 0.8 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Porin_4 PF13609.1 EKE37196.1 - 0.0002 20.9 3.6 0.0002 20.9 2.5 4.7 1 1 2 3 3 3 3 Gram-negative porin DUF3867 PF12983.2 EKE37197.1 - 0.019 14.9 1.7 0.02 14.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) Aldo_ket_red PF00248.16 EKE37197.1 - 0.043 12.6 0.2 0.083 11.7 0.1 1.3 1 1 0 1 1 1 0 Aldo/keto reductase family His_Phos_2 PF00328.17 EKE37197.1 - 0.06 12.6 0.6 0.063 12.5 0.4 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) HTH_Tnp_1 PF01527.15 EKE37197.1 - 0.14 12.1 1.6 9.6 6.2 0.0 2.3 1 1 1 2 2 2 0 Transposase Gemini_AL1_M PF08283.6 EKE37198.1 - 0.018 14.8 1.1 1.1 9.1 0.4 2.8 2 0 0 2 2 2 0 Geminivirus rep protein central domain FAM110_C PF14160.1 EKE37198.1 - 1.7 9.6 9.3 15 6.6 3.8 3.2 2 1 1 3 3 3 0 Centrosome-associated C terminus DUF2575 PF10837.3 EKE37199.1 - 0.053 13.6 1.3 9.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2575) TPR_11 PF13414.1 EKE37200.1 - 6.4e-22 76.9 1.2 3.9e-15 55.2 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EKE37200.1 - 4.2e-17 60.6 0.4 3.4e-05 23.4 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKE37200.1 - 4.5e-17 60.8 6.0 4.9e-06 25.9 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE37200.1 - 4.6e-13 47.9 3.8 1.4e-05 24.5 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EKE37200.1 - 6.1e-10 38.9 0.2 1.4e-06 28.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKE37200.1 - 2.8e-09 37.3 0.0 8.2e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKE37200.1 - 4.6e-09 35.7 0.4 0.0077 16.3 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKE37200.1 - 7.4e-06 26.1 0.0 0.0099 16.4 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37200.1 - 7.8e-06 26.1 0.0 0.00019 21.7 0.0 2.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKE37200.1 - 2e-05 24.0 0.3 0.058 13.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EKE37200.1 - 2.1e-05 24.5 1.0 3.7e-05 23.7 0.2 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EKE37200.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKE37200.1 - 0.00015 21.9 0.6 0.075 13.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3949 PF13133.1 EKE37200.1 - 0.016 15.3 0.7 0.048 13.8 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3949) Fis1_TPR_C PF14853.1 EKE37200.1 - 0.023 14.5 0.9 11 5.9 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EKE37200.1 - 1.8 8.4 9.2 6.3 6.7 0.0 4.0 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain ATP-synt_E_2 PF08112.6 EKE37200.1 - 4.3 7.4 12.9 3.8 7.6 2.6 3.3 1 1 2 3 3 3 0 ATP synthase epsilon subunit DSPc PF00782.15 EKE37201.1 - 1.3e-06 28.0 0.1 3.4e-06 26.6 0.0 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE37201.1 - 2.4e-05 23.8 0.0 5e-05 22.7 0.0 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EKE37201.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_S30 PF04758.9 EKE37202.1 - 7.8e-19 67.1 4.5 8.8e-19 67.0 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Helicase_C_3 PF13625.1 EKE37204.1 - 1.5e-20 73.2 0.0 3.6e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE37204.1 - 6.7e-20 71.6 0.0 6.7e-20 71.6 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKE37204.1 - 4.6e-15 55.2 1.2 1.9e-14 53.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKE37204.1 - 3.5e-12 45.7 0.1 1.2e-11 43.9 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EKE37204.1 - 2.2e-07 30.5 1.4 6.3e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase BOFC_N PF08977.5 EKE37204.1 - 0.021 14.6 0.0 0.063 13.0 0.0 1.8 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal PhoH PF02562.11 EKE37204.1 - 0.029 13.6 0.1 7.4 5.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Pkinase PF00069.20 EKE37205.1 - 3.5e-51 173.8 0.1 4.2e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37205.1 - 5e-50 169.9 0.0 5.9e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE37205.1 - 0.0043 16.1 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE37205.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Exo_endo_phos PF03372.18 EKE37206.1 - 3.3e-22 79.6 0.0 4.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HAD_2 PF13419.1 EKE37207.1 - 3.3e-19 69.7 0.0 3.8e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE37207.1 - 3.4e-08 34.1 0.8 2.1e-07 31.5 0.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EKE37207.1 - 0.0001 22.1 0.1 0.006 16.4 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE37207.1 - 0.00043 20.5 0.0 0.00051 20.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EKE37207.1 - 0.0024 17.5 0.3 0.11 12.0 0.2 2.3 1 1 0 1 1 1 1 Acid Phosphatase Hydrolase_3 PF08282.7 EKE37207.1 - 0.043 13.3 2.2 0.45 10.0 0.1 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acetyltransf_3 PF13302.1 EKE37208.1 - 2.2e-20 73.2 0.0 2.5e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKE37208.1 - 5.7e-12 45.8 0.6 6.6e-12 45.6 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKE37208.1 - 1.1e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EKE37208.1 - 0.0046 16.8 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Toxin_R_bind_C PF07951.7 EKE37208.1 - 0.048 13.3 0.8 0.071 12.7 0.5 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Acetyltransf_7 PF13508.1 EKE37208.1 - 0.051 13.7 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phage_int_SAM_1 PF02899.12 EKE37208.1 - 0.094 12.8 0.3 8.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.20 EKE37209.1 - 1e-67 228.0 0.1 1.2e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37209.1 - 2.6e-34 118.4 0.2 3.5e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37209.1 - 2.9e-07 29.7 0.0 3.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKE37209.1 - 0.002 17.2 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE37209.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKE37209.1 - 0.065 12.5 0.1 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Aldedh PF00171.17 EKE37211.1 - 8.5e-87 291.4 0.0 1e-86 291.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_1b PF00579.20 EKE37212.1 - 1.9e-49 168.3 0.0 1.9e-49 168.3 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (W and Y) Pyridoxal_deC PF00282.14 EKE37212.1 - 5.2e-27 94.2 0.0 3e-26 91.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EKE37212.1 - 0.063 12.4 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF4163 PF13739.1 EKE37212.1 - 7.2 7.4 10.0 7.8 7.3 2.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) HBS1_N PF08938.5 EKE37213.1 - 0.0039 17.2 0.4 0.01 15.9 0.3 1.7 1 0 0 1 1 1 1 HBS1 N-terminus Thioredoxin PF00085.15 EKE37213.1 - 0.015 14.9 0.0 0.14 11.8 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin CDC45 PF02724.9 EKE37214.1 - 1.3 6.9 8.5 1.7 6.5 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 EKE37216.1 - 2.5e-07 30.2 0.0 6.1e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37216.1 - 5.2e-07 29.5 0.0 9.7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 EKE37216.1 - 6.7e-07 29.2 0.8 2.1e-06 27.6 0.5 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 EKE37216.1 - 0.0059 16.3 0.3 0.0098 15.6 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EKE37216.1 - 0.034 14.0 3.4 0.061 13.2 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle RRM_5 PF13893.1 EKE37216.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PulG PF11773.3 EKE37217.1 - 0.12 12.1 0.9 0.18 11.5 0.6 1.2 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin FAM165 PF14981.1 EKE37217.1 - 0.21 11.1 3.9 0.055 12.9 0.8 1.5 2 0 0 2 2 2 0 FAM165 family Baculo_11_kDa PF06143.6 EKE37217.1 - 0.9 8.9 3.5 0.23 10.8 0.2 1.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family Nucleoside_tran PF01733.13 EKE37218.1 - 3.6e-09 36.2 16.3 3.6e-09 36.2 11.3 1.5 1 1 0 1 1 1 1 Nucleoside transporter DNA_pack_C PF02499.10 EKE37219.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus RasGAP PF00616.14 EKE37220.1 - 3.3e-08 33.4 7.9 8.1e-05 22.3 0.3 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase Metallophos PF00149.23 EKE37221.1 - 7.2e-36 123.4 0.2 1.1e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EKE37221.1 - 7.9e-25 86.2 11.6 2.9e-17 62.0 0.4 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EKE37221.1 - 1.9e-19 68.3 7.0 2.7e-06 26.7 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKE37221.1 - 1.4e-16 58.9 4.7 3.2e-05 23.5 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EKE37221.1 - 3.5e-10 39.6 0.4 3.7e-09 36.2 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE37221.1 - 2.3e-09 36.3 4.8 0.00036 20.1 0.2 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE37221.1 - 6.6e-09 35.5 5.2 5.6e-05 22.9 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKE37221.1 - 1.9e-08 34.7 0.5 0.0011 19.6 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37221.1 - 2.5e-08 34.1 0.4 0.00068 19.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKE37221.1 - 4.4e-08 33.0 0.4 0.019 15.5 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKE37221.1 - 1e-07 31.5 2.9 0.0026 17.8 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat PPP5 PF08321.7 EKE37221.1 - 8.5e-05 22.5 1.3 0.00023 21.0 0.9 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_7 PF13176.1 EKE37221.1 - 9.2e-05 21.9 1.0 0.44 10.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.3 EKE37221.1 - 0.00028 19.7 0.1 0.00061 18.6 0.1 1.6 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 EKE37221.1 - 0.001 19.1 4.0 0.001 19.1 2.7 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKE37221.1 - 0.0012 19.1 4.0 1.1 9.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKE37221.1 - 0.041 13.7 0.3 11 5.9 0.0 2.7 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF2442 PF10387.4 EKE37221.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) DUF3808 PF10300.4 EKE37221.1 - 0.17 10.3 2.2 0.17 10.4 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) ABC2_membrane_3 PF12698.2 EKE37222.1 - 2.4e-05 23.5 4.6 2.8e-05 23.3 3.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF998 PF06197.8 EKE37222.1 - 0.034 13.4 2.4 0.048 12.9 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Claudin_2 PF13903.1 EKE37222.1 - 0.051 13.2 6.1 0.063 12.9 4.2 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction KAR9 PF08580.5 EKE37222.1 - 2.5 6.2 6.8 2.7 6.1 4.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF2039 PF10217.4 EKE37224.1 - 0.059 13.3 1.7 0.12 12.4 1.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) CK_II_beta PF01214.13 EKE37225.1 - 5.3e-58 195.5 2.9 6.1e-58 195.3 2.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PP2C PF00481.16 EKE37226.1 - 9.7e-36 123.4 0.2 1.7e-35 122.6 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE37226.1 - 6.9e-07 28.8 1.1 8.9e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C YxiJ PF14176.1 EKE37226.1 - 0.36 10.9 5.3 0.077 13.1 0.9 1.9 2 0 0 2 2 2 0 YxiJ-like protein Peptidase_M48 PF01435.13 EKE37227.1 - 3.4e-31 108.5 0.0 5e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Spore_III_AF PF09581.5 EKE37227.1 - 0.028 14.2 0.7 0.69 9.7 0.1 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) 2TM PF13239.1 EKE37227.1 - 3.8 7.6 11.1 0.047 13.7 1.1 2.6 2 0 0 2 2 2 0 2TM domain YjcQ PF09639.5 EKE37229.1 - 1.5 8.9 6.1 0.66 10.1 0.3 2.4 1 1 1 2 2 2 0 YjcQ protein Tetraspannin PF00335.15 EKE37230.1 - 2.2e-07 30.3 22.7 6.3e-07 28.8 15.8 1.8 1 1 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 EKE37230.1 - 1.6 8.6 16.8 6.6 6.6 11.6 2.0 1 1 0 1 1 1 0 CD20-like family DUF373 PF04123.8 EKE37230.1 - 2 7.3 11.6 0.45 9.4 5.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF443 PF04276.7 EKE37230.1 - 2.2 7.6 6.9 0.93 8.8 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF443) CK_II_beta PF01214.13 EKE37231.1 - 3.1e-64 215.8 1.2 3.6e-64 215.6 0.8 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF3511 PF12023.3 EKE37232.1 - 1.2 8.4 3.6 8.5 5.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) Gly_transf_sug PF04488.10 EKE37233.1 - 0.31 11.4 2.1 0.72 10.2 0.2 2.3 2 1 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif Dopey_N PF04118.9 EKE37234.1 - 6.2e-38 130.2 0.1 8e-38 129.9 0.1 1.0 1 0 0 1 1 1 1 Dopey, N-terminal DUF4487 PF14868.1 EKE37234.1 - 0.036 12.7 0.2 0.76 8.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) Swi3 PF07962.7 EKE37234.1 - 0.071 12.7 0.5 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DUF2417 PF10329.4 EKE37235.1 - 0.041 13.2 2.1 0.049 13.0 1.5 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) SoxY PF13501.1 EKE37236.1 - 0.017 15.1 0.2 0.039 13.9 0.1 1.7 2 0 0 2 2 2 0 Sulfur oxidation protein SoxY BRCT PF00533.21 EKE37236.1 - 0.032 14.3 2.3 0.07 13.2 0.5 2.5 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain Myotub-related PF06602.9 EKE37236.1 - 0.21 10.3 3.2 0.21 10.3 0.8 1.8 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Fe_hyd_lg_C PF02906.9 EKE37237.1 - 9.9e-82 274.3 1.9 1.3e-81 273.9 1.3 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4 PF00037.22 EKE37237.1 - 8.4e-12 44.1 8.0 1.5e-05 24.3 0.5 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fe_hyd_SSU PF02256.12 EKE37237.1 - 2.9e-09 36.7 0.2 5.4e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_7 PF12838.2 EKE37237.1 - 9.9e-09 35.4 19.4 7e-07 29.5 7.1 3.4 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKE37237.1 - 7.8e-08 32.2 5.9 7.8e-08 32.2 4.1 2.4 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EKE37237.1 - 5.6e-07 29.8 4.1 2.8e-06 27.5 2.8 2.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE37237.1 - 6.4e-07 29.0 17.0 8.6e-06 25.4 6.1 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKE37237.1 - 2.5e-06 27.6 7.5 2.5e-06 27.6 5.2 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EKE37237.1 - 1.8e-05 24.5 9.5 0.0028 17.4 0.3 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE37237.1 - 1.8e-05 24.3 7.4 0.00052 19.7 0.8 3.6 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 EKE37237.1 - 2.2e-05 24.9 7.2 0.0096 16.4 0.1 3.4 4 0 0 4 4 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 EKE37237.1 - 9.6e-05 22.7 6.3 0.13 12.7 0.4 3.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE37237.1 - 0.00019 21.1 11.9 0.0054 16.5 0.4 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 EKE37237.1 - 0.00026 21.6 9.4 0.00094 19.8 5.6 2.8 2 1 1 3 3 2 2 4Fe-4S double cluster binding domain Fer4_11 PF13247.1 EKE37237.1 - 3.2 7.6 9.1 4.2 7.3 0.1 3.2 3 1 1 4 4 4 0 4Fe-4S dicluster domain Pro_CA PF00484.14 EKE37238.1 - 4.5e-34 117.6 0.3 5.5e-34 117.3 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PAP2 PF01569.16 EKE37239.1 - 3.9e-22 78.3 1.8 3.9e-22 78.3 1.3 1.4 2 0 0 2 2 2 1 PAP2 superfamily DUF2665 PF11654.3 EKE37239.1 - 0.014 14.9 0.2 0.19 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) Scs3p PF10261.4 EKE37239.1 - 0.022 13.8 0.7 0.03 13.3 0.5 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Intg_mem_TP0381 PF09529.5 EKE37239.1 - 0.038 13.2 0.4 0.038 13.2 0.3 2.2 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) YhhN PF07947.9 EKE37240.1 - 1.9e-22 79.5 23.6 2.4e-22 79.2 16.3 1.2 1 0 0 1 1 1 1 YhhN-like protein HAD_2 PF13419.1 EKE37241.1 - 1.8e-18 67.3 0.0 2.1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE37241.1 - 2.9e-08 33.2 0.0 5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EKE37241.1 - 3.3e-08 34.2 0.0 3e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE37241.1 - 0.014 15.5 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.1 EKE37242.1 - 1.7e-11 43.7 9.9 1.7e-11 43.7 6.9 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE37242.1 - 8.9e-11 41.6 11.4 8.9e-11 41.6 7.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE37242.1 - 2e-09 37.0 8.0 4.8e-09 35.7 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE37242.1 - 3.1e-07 29.9 10.6 3.1e-07 29.9 7.3 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKE37242.1 - 1.4e-06 27.9 3.0 1.4e-06 27.9 2.1 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EKE37242.1 - 1.5e-06 27.9 7.6 1.5e-06 27.9 5.2 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EKE37242.1 - 1.4e-05 25.1 8.1 1.4e-05 25.1 5.6 2.5 3 1 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EKE37242.1 - 0.00016 21.2 7.7 0.00016 21.2 5.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EKE37242.1 - 0.019 14.4 5.6 0.05 13.1 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EKE37242.1 - 0.38 10.6 10.3 0.037 13.8 3.6 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EKE37242.1 - 1.7 8.2 6.9 5.1 6.7 4.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EKE37242.1 - 2.1 8.1 7.3 0.42 10.4 2.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ank_2 PF12796.2 EKE37243.1 - 2.2e-15 56.7 0.7 2.1e-06 27.9 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKE37243.1 - 2.5e-12 45.9 3.8 3.1e-06 26.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Patatin PF01734.17 EKE37243.1 - 6.1e-12 45.9 0.0 1.4e-10 41.4 0.0 2.8 1 1 1 2 2 2 1 Patatin-like phospholipase Ank_5 PF13857.1 EKE37243.1 - 8.5e-12 44.9 0.3 7.3e-06 26.0 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKE37243.1 - 6.5e-11 42.4 2.9 0.00032 21.1 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE37243.1 - 3.9e-08 32.7 7.7 0.00053 19.9 0.0 5.5 7 0 0 7 7 7 2 Ankyrin repeat LRV_FeS PF05484.6 EKE37243.1 - 0.025 14.1 1.0 0.073 12.6 0.7 1.8 1 0 0 1 1 1 0 LRV protein FeS4 cluster DUF1700 PF08006.6 EKE37244.1 - 0.046 13.0 1.1 0.046 13.0 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1700) EFG_IV PF03764.13 EKE37244.1 - 0.12 11.9 6.8 0.19 11.3 0.1 3.0 1 1 2 3 3 3 0 Elongation factor G, domain IV ALS2CR8 PF15299.1 EKE37244.1 - 1.3 8.6 15.6 1.8 8.0 10.8 1.4 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 SSPI PF14098.1 EKE37244.1 - 4.9 7.1 9.2 9.3 6.2 0.2 3.6 2 1 1 3 3 3 0 Small, acid-soluble spore protein I Ground-like PF04155.13 EKE37244.1 - 6.5 7.1 7.1 18 5.6 3.9 2.4 1 1 1 2 2 2 0 Ground-like domain Suf PF05843.9 EKE37246.1 - 1.6e-08 34.6 27.2 0.016 14.9 0.0 5.5 4 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EKE37246.1 - 0.00011 22.4 0.1 0.072 13.4 0.7 4.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKE37246.1 - 0.00041 20.7 0.0 27 5.7 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat PPR_2 PF13041.1 EKE37246.1 - 0.015 15.2 0.3 0.57 10.2 0.0 3.5 3 0 0 3 3 3 0 PPR repeat family TPR_16 PF13432.1 EKE37246.1 - 0.038 14.6 0.1 0.42 11.3 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKE37246.1 - 0.22 11.5 1.7 37 4.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EKE37246.1 - 0.25 11.3 4.0 1.6 8.8 0.1 4.4 6 1 0 6 6 6 0 PPR repeat YaaC PF14175.1 EKE37249.1 - 0.21 10.4 3.2 0.081 11.8 0.5 1.6 2 0 0 2 2 2 0 YaaC-like Protein Ribosomal_60s PF00428.14 EKE37252.1 - 4.6e-20 71.7 8.7 6.2e-20 71.3 6.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pkinase PF00069.20 EKE37253.1 - 1.2e-51 175.3 0.0 2.1e-51 174.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37253.1 - 1.3e-18 67.0 0.0 1.7e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EKE37253.1 - 0.0077 15.6 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Snapin_Pallidin PF14712.1 EKE37254.1 - 3.2e-14 52.9 1.3 3.2e-14 52.9 0.9 1.7 2 0 0 2 2 2 1 Snapin/Pallidin BNIP2 PF12496.3 EKE37254.1 - 0.28 11.3 5.5 0.45 10.6 3.8 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4225 PF13988.1 EKE37254.1 - 0.32 10.4 3.2 0.58 9.6 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) zf-CCHC_3 PF13917.1 EKE37255.1 - 0.00023 20.8 0.9 0.00023 20.8 0.6 2.5 2 0 0 2 2 2 1 Zinc knuckle DUF3884 PF13024.1 EKE37255.1 - 0.026 13.9 0.6 0.073 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) zf-CCHC PF00098.18 EKE37255.1 - 0.046 13.6 16.4 0.052 13.4 3.0 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EKE37255.1 - 0.08 12.6 11.5 0.22 11.1 2.8 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EKE37255.1 - 0.45 10.2 15.2 0.66 9.6 1.3 2.7 2 0 0 2 2 2 0 Zinc knuckle Myotub-related PF06602.9 EKE37257.1 - 6.5e-90 301.4 0.0 9.8e-90 300.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain RA PF00788.18 EKE37257.1 - 0.0041 17.5 0.4 0.65 10.5 0.0 3.3 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Y_phosphatase PF00102.22 EKE37257.1 - 0.0084 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EKE37257.1 - 0.029 13.9 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EKE37257.1 - 0.035 14.3 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family RabGAP-TBC PF00566.13 EKE37259.1 - 4.6e-08 32.7 7.4 2e-07 30.6 3.4 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 EKE37259.1 - 0.0032 17.7 0.1 0.011 16.0 0.1 1.9 1 1 0 1 1 1 1 Rhodanese-like domain Metallophos PF00149.23 EKE37260.1 - 3.7e-08 32.9 3.9 7.7e-08 31.9 2.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE37260.1 - 4.7e-08 33.0 0.0 7.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EKE37260.1 - 8e-05 21.9 0.0 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily RhoGAP PF00620.22 EKE37261.1 - 4.9e-20 71.6 0.4 3.1e-19 69.0 0.0 2.4 3 0 0 3 3 3 1 RhoGAP domain DUF3614 PF12267.3 EKE37261.1 - 0.25 11.6 4.7 0.51 10.6 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Pkinase PF00069.20 EKE37262.1 - 2.9e-65 220.0 1.3 3.5e-65 219.7 0.1 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37262.1 - 1.5e-48 165.1 0.0 2.2e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37262.1 - 0.00019 20.4 0.0 0.00079 18.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Radical_SAM PF04055.16 EKE37262.1 - 0.087 12.9 1.2 15 5.7 0.2 2.5 2 0 0 2 2 2 0 Radical SAM superfamily TORC_N PF12884.2 EKE37262.1 - 3.9 8.0 11.5 0.19 12.2 2.7 2.5 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus MRP-S27 PF10037.4 EKE37263.1 - 0.0036 16.2 0.7 0.0044 16.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 SieB PF14163.1 EKE37263.1 - 0.067 12.7 0.2 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B LMSTEN PF07988.7 EKE37263.1 - 0.12 11.6 0.2 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 LMSTEN motif UBA_4 PF14555.1 EKE37264.1 - 0.00014 21.3 0.0 0.0003 20.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Baculo_PEP_C PF04513.7 EKE37266.1 - 0.063 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.14 EKE37266.1 - 0.18 11.3 6.0 0.26 10.7 4.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ABC2_membrane_5 PF13346.1 EKE37267.1 - 0.015 14.5 1.5 0.019 14.2 1.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1404 PF07185.6 EKE37267.1 - 0.073 12.6 0.5 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) zf-DHHC PF01529.15 EKE37267.1 - 0.091 12.1 2.5 0.14 11.5 1.7 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Shisa PF13908.1 EKE37267.1 - 0.98 9.5 6.1 0.087 13.0 0.3 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RRM_1 PF00076.17 EKE37268.1 - 1.7e-12 46.8 0.0 3.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37268.1 - 1.8e-10 40.6 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE37268.1 - 1.1e-05 25.2 0.1 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mto2_bdg PF12808.2 EKE37268.1 - 0.51 10.4 7.5 5.3 7.2 0.7 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Autophagy_act_C PF03987.10 EKE37269.1 - 4.4e-10 39.5 0.3 4.4e-10 39.5 0.2 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain SAGA-Tad1 PF12767.2 EKE37270.1 - 0.014 15.0 4.5 0.022 14.4 0.8 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase_Tyr PF07714.12 EKE37272.1 - 4.2e-49 166.9 0.0 6.5e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37272.1 - 1.1e-40 139.4 0.0 2e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Oxidored_nitro PF00148.14 EKE37272.1 - 0.041 12.5 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ribonuclease_3 PF00636.21 EKE37274.1 - 0.0092 16.4 0.3 0.45 10.9 0.1 3.0 2 1 0 2 2 2 1 Ribonuclease III domain V-ATPase_H_C PF11698.3 EKE37275.1 - 1.1e-36 125.2 0.1 3.7e-36 123.6 0.0 1.9 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 EKE37275.1 - 5.8e-20 71.6 11.9 8e-20 71.1 8.3 1.1 1 0 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.17 EKE37275.1 - 0.053 13.6 0.5 0.93 9.7 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat Acetyltransf_1 PF00583.19 EKE37276.1 - 5e-13 48.8 0.1 6.4e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE37276.1 - 7.9e-08 32.3 0.2 1.3e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE37276.1 - 0.00015 21.8 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE37276.1 - 0.025 14.4 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DENN PF02141.16 EKE37277.1 - 9.3e-18 64.6 8.8 2e-17 63.4 3.0 3.0 2 1 0 2 2 2 1 DENN (AEX-3) domain TLD PF07534.11 EKE37278.1 - 7.4e-05 22.7 2.3 0.00072 19.5 0.0 3.0 3 0 0 3 3 3 1 TLD TF_Zn_Ribbon PF08271.7 EKE37278.1 - 0.26 10.6 3.4 6 6.2 0.0 3.9 4 0 0 4 4 4 0 TFIIB zinc-binding DUF4349 PF14257.1 EKE37280.1 - 0.0045 16.2 2.1 0.0059 15.8 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) AAA_13 PF13166.1 EKE37280.1 - 0.0072 14.8 2.7 0.0089 14.5 1.9 1.1 1 0 0 1 1 1 1 AAA domain TraC PF07820.7 EKE37280.1 - 0.015 15.4 1.9 0.022 14.9 0.6 1.8 2 0 0 2 2 2 0 TraC-like protein CP12 PF02672.10 EKE37280.1 - 0.03 14.7 1.5 0.99 9.9 0.0 2.4 2 0 0 2 2 2 0 CP12 domain AAA_23 PF13476.1 EKE37280.1 - 0.1 12.9 4.4 0.12 12.7 3.1 1.3 1 0 0 1 1 1 0 AAA domain DUF607 PF04678.8 EKE37280.1 - 0.11 12.3 0.3 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 SlyX PF04102.7 EKE37280.1 - 0.22 11.9 4.0 0.22 11.9 1.2 2.2 2 1 0 2 2 2 0 SlyX IncA PF04156.9 EKE37280.1 - 0.3 10.6 4.0 0.87 9.1 2.8 1.7 1 1 0 1 1 1 0 IncA protein GvpL_GvpF PF06386.6 EKE37280.1 - 0.31 10.5 3.3 0.94 9.0 1.7 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ATP-synt_B PF00430.13 EKE37280.1 - 0.43 10.3 10.4 0.76 9.5 7.2 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) ERM PF00769.14 EKE37280.1 - 0.46 9.9 9.8 0.71 9.3 6.4 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_L34e PF01199.13 EKE37281.1 - 2.9e-31 107.5 5.4 2.9e-31 107.5 3.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L34e Lar_restr_allev PF14354.1 EKE37281.1 - 0.096 12.9 1.0 11 6.3 0.4 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF3133 PF11331.3 EKE37281.1 - 0.53 9.8 3.7 0.98 9.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) TPR_11 PF13414.1 EKE37282.1 - 1.4e-19 69.4 2.6 3.4e-14 52.2 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKE37282.1 - 6.5e-13 47.6 4.9 0.00078 18.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKE37282.1 - 7.6e-10 37.9 1.0 0.057 13.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EKE37282.1 - 9e-06 25.7 3.4 2.6e-05 24.2 2.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EKE37282.1 - 8.6e-05 22.4 0.7 0.0031 17.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37282.1 - 0.00018 21.7 0.3 0.13 12.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE37282.1 - 0.00052 19.9 1.1 0.51 10.3 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKE37282.1 - 0.0059 16.4 0.6 0.063 13.1 0.2 2.4 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.4 EKE37282.1 - 0.045 12.3 0.1 0.058 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Arf PF00025.16 EKE37283.1 - 1.5e-67 226.1 0.0 1.7e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKE37283.1 - 6.1e-15 54.8 0.0 7.6e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EKE37283.1 - 1.5e-13 50.2 0.5 1.3e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EKE37283.1 - 2.5e-13 49.7 0.0 3.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EKE37283.1 - 2e-09 36.9 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EKE37283.1 - 5.8e-07 30.0 0.0 8.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKE37283.1 - 0.0017 18.2 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EKE37283.1 - 0.033 13.2 0.1 0.042 12.9 0.1 1.3 1 1 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.7 EKE37283.1 - 0.13 11.9 0.1 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AA_permease_2 PF13520.1 EKE37284.1 - 2e-24 85.9 51.1 2e-24 85.9 35.4 1.5 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EKE37284.1 - 2.1e-15 56.0 40.5 3.2e-15 55.4 28.1 1.2 1 0 0 1 1 1 1 Amino acid permease Hum_adeno_E3A PF05393.6 EKE37284.1 - 0.14 11.8 5.0 0.65 9.7 0.9 2.8 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein FYVE_2 PF02318.11 EKE37285.1 - 0.023 14.5 2.0 0.043 13.7 1.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Atg14 PF10186.4 EKE37285.1 - 3.7 6.3 12.5 5.7 5.7 8.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mt_ATP-synt_D PF05873.7 EKE37286.1 - 0.011 15.3 3.2 0.013 15.1 2.2 1.0 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) OmpH PF03938.9 EKE37286.1 - 0.068 13.1 3.2 0.077 12.9 2.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EKE37286.1 - 0.081 11.3 6.0 0.082 11.3 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spore_III_AB PF09548.5 EKE37286.1 - 0.1 12.3 0.3 0.1 12.3 0.2 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF908 PF06012.7 EKE37286.1 - 0.11 11.7 3.8 0.11 11.7 2.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF501 PF04417.7 EKE37286.1 - 0.13 12.1 0.6 0.13 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) THOC7 PF05615.8 EKE37286.1 - 0.15 12.2 7.6 0.2 11.9 5.3 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF3735 PF12537.3 EKE37286.1 - 0.21 11.6 2.2 9.5 6.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) ATP-synt_E PF05680.7 EKE37286.1 - 7.3 6.6 10.5 3.1 7.8 2.9 2.0 1 1 1 2 2 2 0 ATP synthase E chain Ras PF00071.17 EKE37287.1 - 1.2e-53 180.7 0.3 1.4e-53 180.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37287.1 - 2e-18 66.9 0.1 4.8e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE37287.1 - 3.4e-09 36.1 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE37287.1 - 4.4e-08 32.7 0.0 4.5e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE37287.1 - 1.5e-07 31.3 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE37287.1 - 3.2e-05 23.2 0.1 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EKE37287.1 - 0.0028 17.1 0.0 0.01 15.3 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EKE37287.1 - 0.0071 16.0 0.0 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EKE37287.1 - 0.0083 15.3 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EKE37287.1 - 0.038 12.9 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Septin SRPRB PF09439.5 EKE37287.1 - 0.058 12.6 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EKE37287.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EKE37287.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ribophorin_I PF04597.9 EKE37288.1 - 2.4e-22 79.0 16.4 3.3e-22 78.6 11.4 1.1 1 0 0 1 1 1 1 Ribophorin I DDE_1 PF03184.14 EKE37289.1 - 5.8e-13 48.4 1.9 5.8e-13 48.4 1.3 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease His_kinase PF06580.8 EKE37289.1 - 0.0069 16.2 1.0 6.1 6.8 0.0 3.4 3 0 0 3 3 3 2 Histidine kinase DUF565 PF04483.7 EKE37289.1 - 0.22 11.7 2.4 1 9.5 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF565) YbaJ PF10757.4 EKE37289.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.7 3 0 0 3 3 3 0 Biofilm formation regulator YbaJ Cullin PF00888.17 EKE37290.1 - 2.3e-43 148.6 50.5 4e-43 147.8 31.6 2.0 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 EKE37290.1 - 4.3e-16 58.4 4.9 3.5e-15 55.5 0.3 3.6 4 0 0 4 4 4 1 Cullin protein neddylation domain Zn_ribbon_2 PF12674.2 EKE37290.1 - 0.094 13.0 5.5 0.16 12.3 0.1 3.9 3 0 0 3 3 3 0 Putative zinc ribbon domain Cryptochrome_C PF12546.3 EKE37291.1 - 0.29 11.8 8.4 0.41 11.3 5.8 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Lipase_3 PF01764.20 EKE37292.1 - 9.9e-11 41.4 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EKE37292.1 - 0.0015 17.9 0.1 0.039 13.3 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 EKE37292.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Na_Ca_ex PF01699.19 EKE37292.1 - 0.018 14.6 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Abhydrolase_5 PF12695.2 EKE37292.1 - 0.031 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE37292.1 - 0.052 13.4 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.3 EKE37292.1 - 0.076 12.0 1.5 0.13 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Thioesterase PF00975.15 EKE37292.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF3089 PF11288.3 EKE37292.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Acetyltransf_1 PF00583.19 EKE37293.1 - 9.3e-11 41.6 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKE37293.1 - 2e-08 34.3 0.0 3.3e-08 33.6 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKE37293.1 - 2.1e-07 31.0 0.5 2.8e-07 30.6 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKE37293.1 - 5.4e-06 26.4 0.0 1e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKE37293.1 - 5.8e-06 26.5 0.0 7.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKE37293.1 - 0.00015 21.6 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EKE37293.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKE37293.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.1 EKE37293.1 - 0.089 12.5 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF1838 PF08894.6 EKE37293.1 - 0.096 11.8 0.1 0.29 10.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1838) Baculo_11_kDa PF06143.6 EKE37294.1 - 0.0057 15.9 5.0 0.033 13.5 0.7 2.7 2 0 0 2 2 2 1 Baculovirus 11 kDa family MRAP PF15183.1 EKE37294.1 - 0.015 14.8 0.1 0.015 14.8 0.1 2.5 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family PIRT PF15099.1 EKE37294.1 - 0.068 12.3 4.4 0.095 11.9 1.9 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family AA_permease_2 PF13520.1 EKE37294.1 - 0.078 11.5 13.8 1.5 7.2 9.6 2.1 1 1 0 1 1 1 0 Amino acid permease EcsB PF05975.7 EKE37294.1 - 0.092 11.1 4.3 1.6 7.0 0.4 2.1 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB EphA2_TM PF14575.1 EKE37294.1 - 0.11 12.8 0.1 0.11 12.8 0.0 3.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.11 EKE37294.1 - 0.18 10.5 11.4 0.73 8.4 5.3 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily ODV-E18 PF10717.4 EKE37294.1 - 0.3 10.5 4.7 0.06 12.7 0.7 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 COX2_TM PF02790.10 EKE37294.1 - 0.39 10.7 10.8 0.94 9.4 0.5 3.1 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Cytochrom_C_asm PF01578.15 EKE37294.1 - 0.65 9.5 12.6 0.49 9.9 0.4 3.0 2 1 1 3 3 3 0 Cytochrome C assembly protein DUF1514 PF07438.6 EKE37294.1 - 0.89 9.5 4.8 1.8 8.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF843 PF05814.6 EKE37294.1 - 3.8 7.3 13.9 0.21 11.4 0.5 2.8 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Pkinase_Tyr PF07714.12 EKE37295.1 - 2.7e-52 177.4 0.0 4.6e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37295.1 - 8.3e-49 166.0 0.0 1.9e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EKE37295.1 - 0.0041 16.2 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKE37295.1 - 0.04 13.2 0.1 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Auxin_repressed PF05564.7 EKE37295.1 - 1.9 9.1 4.7 0.71 10.4 0.8 2.1 2 0 0 2 2 2 0 Dormancy/auxin associated protein DUF2116 PF09889.4 EKE37296.1 - 0.41 10.4 9.0 0.94 9.3 3.7 2.9 2 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) HSP70 PF00012.15 EKE37297.1 - 1.5e-109 366.6 12.2 1.9e-109 366.2 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE37297.1 - 1e-14 53.9 3.1 2.2e-11 42.9 0.4 3.4 3 0 0 3 3 3 3 MreB/Mbl protein StbA PF06406.6 EKE37297.1 - 0.00045 19.2 0.4 0.0022 16.9 0.2 2.2 1 1 1 2 2 2 1 StbA protein DUF4445 PF14574.1 EKE37297.1 - 0.0051 15.1 0.0 0.048 11.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4445) Phage_int_SAM_3 PF14659.1 EKE37297.1 - 0.051 13.8 3.3 14 6.0 0.0 3.5 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain IncA PF04156.9 EKE37297.1 - 0.15 11.6 3.2 0.38 10.3 2.2 1.6 1 0 0 1 1 1 0 IncA protein DUF1136 PF06582.7 EKE37298.1 - 0.15 11.7 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) RNA_pol_L_2 PF13656.1 EKE37298.1 - 0.4 10.1 5.1 0.18 11.2 0.1 2.8 2 1 1 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain RNase_T PF00929.19 EKE37299.1 - 0.053 13.7 0.5 0.15 12.3 0.3 1.8 1 0 0 1 1 1 0 Exonuclease C1-set PF07654.10 EKE37299.1 - 0.057 13.4 0.6 6.1 6.9 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin C1-set domain HSP70 PF00012.15 EKE37300.1 - 4.9e-37 127.1 5.9 5.4e-27 93.9 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein HSP70 PF00012.15 EKE37301.1 - 1.4e-19 69.4 0.0 1.7e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Pkinase PF00069.20 EKE37302.1 - 5.2e-32 111.0 4.8 1.1e-31 109.8 0.9 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37302.1 - 2.5e-16 59.5 7.5 5.4e-16 58.4 0.6 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EKE37302.1 - 2.1e-05 23.6 0.0 0.00021 20.3 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EKE37303.1 - 7.5e-52 176.0 0.1 1.9e-51 174.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37303.1 - 2.7e-48 164.3 0.1 9.4e-48 162.5 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase VSP PF03302.8 EKE37303.1 - 3e-08 32.7 138.9 3.1e-06 26.0 46.0 4.6 1 1 3 4 4 4 3 Giardia variant-specific surface protein bZIP_Maf PF03131.12 EKE37304.1 - 4.4e-18 65.3 8.9 4.4e-18 65.3 6.2 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EKE37304.1 - 4.4e-07 29.7 8.7 4.4e-07 29.7 6.0 2.8 3 1 1 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.10 EKE37304.1 - 0.00033 20.4 11.3 0.00033 20.4 7.8 2.6 2 1 1 3 3 3 1 Basic region leucine zipper DUF3510 PF12022.3 EKE37304.1 - 0.055 13.5 4.9 0.046 13.8 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF2810 PF10928.3 EKE37304.1 - 0.08 12.6 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) DUF1192 PF06698.6 EKE37304.1 - 0.24 11.2 1.9 0.81 9.5 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF87 PF01935.12 EKE37304.1 - 1.1 9.0 4.3 1.5 8.5 2.5 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF342 PF03961.8 EKE37304.1 - 2.5 6.4 6.5 3 6.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EKE37304.1 - 8.4 5.9 7.8 13 5.3 5.4 1.3 1 0 0 1 1 1 0 IncA protein PARG_cat PF05028.9 EKE37305.1 - 1.1e-41 143.2 2.5 1.7e-41 142.6 1.7 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Ras PF00071.17 EKE37306.1 - 1.1e-42 145.1 0.0 1.5e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37306.1 - 7.3e-17 61.9 0.9 1e-16 61.5 0.1 1.6 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EKE37306.1 - 4.5e-11 42.3 0.0 5.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE37306.1 - 6e-05 22.9 0.4 0.00011 22.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE37306.1 - 0.00043 19.7 0.0 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE37306.1 - 0.0021 17.2 0.1 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EKE37306.1 - 0.0028 16.8 0.0 0.052 12.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EKE37306.1 - 0.0036 17.0 0.3 0.0042 16.8 0.2 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 EKE37306.1 - 0.0094 15.5 0.5 2.7 7.5 0.0 2.5 2 1 0 2 2 2 2 AAA domain Septin PF00735.13 EKE37306.1 - 0.01 14.8 0.7 0.025 13.5 0.0 1.9 2 1 0 2 2 2 0 Septin PduV-EutP PF10662.4 EKE37306.1 - 0.012 15.0 0.2 0.042 13.3 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EKE37306.1 - 0.051 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EKE37306.1 - 0.052 12.7 0.6 0.097 11.8 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_hydro_18 PF00704.23 EKE37307.1 - 1.2e-06 28.2 0.9 1.9e-06 27.6 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PI3_PI4_kinase PF00454.22 EKE37308.1 - 3.9e-13 49.4 0.2 4.6e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Chorein_N PF12624.2 EKE37310.1 - 3.2e-09 36.3 2.1 3.2e-09 36.3 1.4 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF3240 PF11582.3 EKE37310.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Amidohydro_1 PF01979.15 EKE37311.1 - 4.1e-41 141.7 0.0 4.9e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKE37311.1 - 7.8e-09 35.2 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EKE37311.1 - 4.5e-05 22.8 0.0 0.0024 17.1 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family RHH_1 PF01402.16 EKE37311.1 - 0.021 14.6 0.2 4.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Amidohydro_4 PF13147.1 EKE37311.1 - 0.028 14.4 0.0 0.073 13.0 0.0 1.7 2 0 0 2 2 2 0 Amidohydrolase T4_baseplate PF12322.3 EKE37312.1 - 0.0061 15.8 0.4 0.013 14.8 0.3 1.5 1 0 0 1 1 1 1 T4 bacteriophage base plate protein Peptidase_S41 PF03572.13 EKE37312.1 - 0.015 14.7 0.0 0.038 13.3 0.0 1.7 1 1 0 1 1 1 0 Peptidase family S41 EutQ PF06249.7 EKE37312.1 - 0.075 12.5 0.1 0.56 9.7 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation protein EutQ EF-hand_1 PF00036.27 EKE37313.1 - 1.3e-26 89.8 21.9 4.9e-08 31.7 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKE37313.1 - 1.5e-24 85.9 9.6 6.1e-14 51.9 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE37313.1 - 1.4e-23 80.5 14.5 1.6e-06 27.4 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKE37313.1 - 5.1e-22 76.1 8.4 0.0001 21.4 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EKE37313.1 - 2.6e-16 58.9 21.6 5.2e-05 22.7 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 EKE37313.1 - 3.5e-07 29.9 11.7 0.03 14.0 1.2 3.6 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EKE37313.1 - 8.9e-07 28.9 3.7 0.003 17.5 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EKE37313.1 - 3.8e-06 26.4 7.8 0.0039 16.8 0.3 4.1 2 1 2 4 4 4 3 EF hand EF-hand_9 PF14658.1 EKE37313.1 - 0.0076 16.1 2.6 0.33 10.9 0.2 2.7 2 2 0 2 2 2 1 EF-hand domain DUF2141 PF09912.4 EKE37313.1 - 0.028 14.0 0.5 0.39 10.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) PMBR PF09373.5 EKE37313.1 - 0.15 12.0 0.1 8.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat Csm1 PF12539.3 EKE37313.1 - 0.2 12.1 2.2 22 5.5 0.1 3.3 1 1 3 4 4 4 0 Chromosome segregation protein Csm1/Pcs1 FG-GAP PF01839.18 EKE37313.1 - 1.5 8.5 4.8 4.3 7.1 0.3 2.5 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.1 EKE37313.1 - 2.2 8.6 7.7 26 5.2 0.1 3.6 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CXCR4_N PF12109.3 EKE37313.1 - 3 7.7 5.3 0.81 9.5 0.8 2.1 2 0 0 2 2 2 0 CXCR4 Chemokine receptor N terminal zf-CCCH PF00642.19 EKE37314.1 - 5.1e-16 57.9 29.8 1.6e-05 24.4 1.6 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EKE37314.1 - 0.098 12.6 32.7 0.11 12.5 3.6 4.7 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type A_deamin PF02137.13 EKE37315.1 - 6.2e-53 180.3 0.2 8e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF1837 PF08878.6 EKE37317.1 - 0.015 14.8 6.8 0.053 13.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) DUF1542 PF07564.6 EKE37317.1 - 0.03 14.3 1.2 0.088 12.8 0.9 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF2228 PF10228.4 EKE37317.1 - 0.65 9.5 10.3 0.035 13.6 2.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) DUF3153 PF11353.3 EKE37317.1 - 5.8 6.2 8.7 33 3.8 6.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) PcfK PF14058.1 EKE37317.1 - 9.8 6.3 9.7 0.6 10.2 0.4 2.5 2 0 0 2 2 2 0 PcfK-like protein Dna2 PF08696.6 EKE37318.1 - 0.0054 16.0 7.2 0.0054 16.0 5.0 1.8 1 1 0 2 2 2 1 DNA replication factor Dna2 RasGAP_C PF03836.10 EKE37318.1 - 0.014 15.0 9.7 0.014 15.0 6.7 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Pil1 PF13805.1 EKE37318.1 - 0.036 13.2 7.0 0.17 10.9 3.9 1.9 1 1 1 2 2 2 0 Eisosome component PIL1 DUF356 PF04009.7 EKE37318.1 - 0.09 12.8 0.9 0.38 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF356) Patched PF02460.13 EKE37318.1 - 0.95 7.2 8.0 1.1 7.0 5.5 1.1 1 0 0 1 1 1 0 Patched family Iron_permease PF04120.7 EKE37318.1 - 1.1 8.8 7.9 0.34 10.4 2.4 2.0 2 0 0 2 2 2 0 Low affinity iron permease Drf_FH3 PF06367.11 EKE37318.1 - 2.4 7.5 13.6 0.7 9.2 7.2 1.6 1 1 1 2 2 2 0 Diaphanous FH3 Domain Histone_HNS PF00816.16 EKE37318.1 - 3.9 8.0 7.2 2 9.0 1.8 2.2 2 0 0 2 2 2 0 H-NS histone family PRP1_N PF06424.7 EKE37318.1 - 7.8 6.8 21.6 4.5 7.5 1.6 2.5 1 1 0 2 2 2 0 PRP1 splicing factor, N-terminal Ribosomal_S7e PF01251.13 EKE37319.1 - 6.7e-24 84.4 0.8 7.7e-24 84.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Adaptin_N PF01602.15 EKE37320.1 - 6.9e-77 258.9 13.1 6.9e-77 258.9 9.1 1.4 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EKE37320.1 - 1e-30 106.5 4.0 1e-30 106.5 2.8 1.9 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EKE37320.1 - 7.7e-07 29.3 1.8 0.18 12.0 0.0 4.3 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EKE37320.1 - 0.0001 22.1 0.1 7.2 6.9 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EKE37320.1 - 0.0016 18.3 3.5 0.2 11.4 0.1 3.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF1379 PF07126.7 EKE37320.1 - 0.046 13.1 0.3 21 4.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1379) TPK_B1_binding PF04265.9 EKE37320.1 - 0.2 11.3 1.6 35 4.1 0.0 3.6 3 1 0 3 3 3 0 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF3952 PF13130.1 EKE37323.1 - 0.33 10.9 3.0 0.49 10.3 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) DUF1963 PF09234.5 EKE37324.1 - 5.6e-52 177.1 3.1 6.6e-52 176.9 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) WD40 PF00400.27 EKE37325.1 - 1.7e-26 91.1 13.6 1.1e-09 37.8 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Lactonase PF10282.4 EKE37325.1 - 0.032 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DNA_gyraseB PF00204.20 EKE37326.1 - 0.14 11.3 0.3 0.21 10.7 0.2 1.3 1 0 0 1 1 1 0 DNA gyrase B LIM PF00412.17 EKE37327.1 - 3.8e-53 177.3 64.5 4.7e-13 48.9 4.3 5.2 5 0 0 5 5 5 5 LIM domain DUF35_N PF12172.3 EKE37327.1 - 0.13 12.2 0.1 0.13 12.2 0.1 4.2 3 1 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) SBP_bac_7 PF03480.8 EKE37327.1 - 1.7 7.7 7.6 2.3 7.2 5.3 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 NARP1 PF12569.3 EKE37327.1 - 1.7 7.2 17.5 2.2 6.9 12.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DZR PF12773.2 EKE37327.1 - 6 6.7 69.3 2.3 8.0 2.8 8.2 2 2 3 5 5 5 0 Double zinc ribbon Peptidase_M3 PF01432.15 EKE37328.1 - 1.6e-117 393.3 3.9 3e-117 392.4 2.7 1.5 1 0 0 1 1 1 1 Peptidase family M3 Myb_DNA-binding PF00249.26 EKE37329.1 - 2.2e-09 37.2 0.3 6.6e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE37329.1 - 7.8e-05 22.7 0.3 0.00023 21.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKE37329.1 - 0.014 15.2 4.1 0.25 11.2 0.4 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain XPC-binding PF09280.6 EKE37329.1 - 0.25 10.8 2.3 1.2 8.6 0.3 2.8 2 0 0 2 2 2 0 XPC-binding domain Myb_DNA-binding PF00249.26 EKE37331.1 - 7.3e-10 38.7 1.1 7.5e-09 35.5 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE37331.1 - 4.5e-05 23.4 0.6 0.00012 22.0 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKE37331.1 - 0.015 15.1 5.0 0.17 11.8 0.7 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_18 PF13238.1 EKE37332.1 - 2.2e-25 89.4 0.1 3.1e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE37332.1 - 6.4e-14 52.8 0.1 8.7e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EKE37332.1 - 0.00019 21.6 0.1 0.00041 20.5 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EKE37332.1 - 0.00058 18.9 0.0 0.00096 18.2 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EKE37332.1 - 0.00092 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EKE37332.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKE37332.1 - 0.0048 16.8 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ADK PF00406.17 EKE37332.1 - 0.0053 16.6 0.0 0.08 12.8 0.0 2.3 1 1 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 EKE37332.1 - 0.0088 15.9 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKE37332.1 - 0.0089 16.1 0.5 0.041 14.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 EKE37332.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EKE37332.1 - 0.03 14.2 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKE37332.1 - 0.055 13.1 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EKE37332.1 - 0.058 12.4 0.0 0.11 11.6 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EKE37332.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Cytidylate_kin2 PF13189.1 EKE37332.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family FtsK_SpoIIIE PF01580.13 EKE37332.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EKE37332.1 - 0.094 12.1 0.1 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EKE37332.1 - 0.17 11.3 0.2 0.32 10.3 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein MFS_1 PF07690.11 EKE37334.1 - 8.9e-12 44.3 38.2 1.8e-09 36.8 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Apyrase PF06079.6 EKE37336.1 - 8.9e-55 185.8 7.0 1.1e-54 185.5 4.8 1.1 1 0 0 1 1 1 1 Apyrase DUF2414 PF10309.4 EKE37336.1 - 0.68 9.6 6.6 4.7 6.9 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2414) Rep_2 PF01719.12 EKE37337.1 - 0.011 15.3 1.6 0.41 10.1 0.3 2.4 1 1 1 2 2 2 0 Plasmid replication protein NYN PF01936.13 EKE37337.1 - 0.016 15.4 0.1 0.058 13.6 0.0 1.8 2 0 0 2 2 2 0 NYN domain UPF0565 PF10561.4 EKE37337.1 - 0.03 13.2 0.3 0.041 12.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 VAR1 PF05316.7 EKE37337.1 - 0.048 12.2 10.6 0.069 11.7 7.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) GAS2 PF02187.12 EKE37337.1 - 0.091 12.5 0.1 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain EF-hand_7 PF13499.1 EKE37340.1 - 3.7e-15 55.8 3.7 1.5e-14 53.8 0.2 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EKE37340.1 - 3.8e-15 53.9 4.4 1.2e-06 27.4 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EKE37340.1 - 5e-11 41.5 4.3 2.2e-05 23.9 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EKE37340.1 - 1.4e-10 40.0 3.7 0.00012 21.2 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EKE37340.1 - 3.4e-08 32.9 4.3 0.00019 20.9 0.3 3.6 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKE37340.1 - 5e-05 23.2 0.1 9.1e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKE37340.1 - 6.1e-05 22.7 1.1 0.051 13.3 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Coat_F PF07875.7 EKE37340.1 - 0.025 14.7 0.1 16 5.6 0.0 3.2 3 0 0 3 3 3 0 Coat F domain KSR1-SAM PF13543.1 EKE37340.1 - 0.039 13.7 0.2 0.75 9.5 0.1 2.3 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 EF-hand_9 PF14658.1 EKE37340.1 - 0.06 13.2 0.1 1 9.3 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain TerB PF05099.8 EKE37340.1 - 0.13 12.0 1.1 3.7 7.2 0.1 2.9 1 1 2 3 3 3 0 Tellurite resistance protein TerB tRNA_m1G_MT PF01746.16 EKE37341.1 - 7.4e-26 90.8 1.5 7.4e-26 90.8 1.1 1.5 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase PRP3 PF08572.5 EKE37341.1 - 0.014 14.7 14.4 0.031 13.6 10.0 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Apis_Csd PF11671.3 EKE37341.1 - 0.09 12.5 3.5 0.19 11.5 2.5 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein OmpH PF03938.9 EKE37341.1 - 1.3 8.9 5.8 3.5 7.5 4.0 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_M18 PF02127.10 EKE37342.1 - 6.5e-105 351.1 0.1 7.7e-105 350.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EKE37342.1 - 0.00038 19.3 0.6 0.081 11.6 0.1 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase GDPD PF03009.12 EKE37343.1 - 5.3e-49 167.0 0.0 9.8e-49 166.1 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family M16C_assoc PF08367.6 EKE37344.1 - 4.3e-33 114.1 2.2 7.7e-33 113.3 1.5 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EKE37344.1 - 6.2e-22 78.1 4.4 3e-14 53.1 0.3 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EKE37344.1 - 0.00078 19.2 0.3 0.013 15.2 0.0 3.1 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) MIT PF04212.13 EKE37346.1 - 4.4e-08 32.8 5.8 4e-07 29.8 0.4 3.3 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain Glutaredoxin2_C PF04399.8 EKE37346.1 - 0.53 9.8 5.3 1.5 8.3 1.1 2.6 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF29 PF01724.11 EKE37346.1 - 0.65 9.8 10.2 0.11 12.3 2.7 2.6 2 2 0 2 2 2 0 Domain of unknown function DUF29 DUF2870 PF11069.3 EKE37346.1 - 1.4 9.0 6.3 0.42 10.6 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Ndc1_Nup PF09531.5 EKE37346.1 - 2.4 6.4 10.2 3.1 6.1 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FliJ PF02050.11 EKE37346.1 - 2.9 7.9 28.8 0.16 12.0 11.4 3.1 2 1 0 2 2 2 0 Flagellar FliJ protein DUF3333 PF11812.3 EKE37346.1 - 3.3 7.7 13.1 0.4 10.6 3.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3333) Aida_N PF08910.5 EKE37346.1 - 4.6 7.5 7.8 47 4.2 0.0 3.7 2 2 2 4 4 4 0 Aida N-terminus Thioredoxin PF00085.15 EKE37347.1 - 8e-22 76.8 0.1 9.3e-22 76.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE37347.1 - 7.5e-05 22.8 0.6 0.00099 19.2 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EKE37347.1 - 0.00078 19.4 0.2 0.0014 18.6 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKE37347.1 - 0.00084 19.4 0.1 0.002 18.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like ERp29_N PF07912.8 EKE37347.1 - 0.026 14.4 0.1 0.039 13.8 0.1 1.3 1 1 0 1 1 1 0 ERp29, N-terminal domain Haemolytic PF01809.13 EKE37347.1 - 0.032 13.8 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Haemolytic domain Thioredoxin_7 PF13899.1 EKE37347.1 - 0.042 13.8 0.2 0.075 13.0 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 EKE37347.1 - 0.16 11.5 0.3 0.25 10.8 0.2 1.5 1 1 0 1 1 1 0 Redoxin DSBA PF01323.15 EKE37347.1 - 0.29 10.6 1.2 1.3 8.5 0.6 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Ded_cyto PF06920.8 EKE37348.1 - 1.8e-08 33.8 0.9 1.8e-08 33.8 0.6 4.0 4 1 0 4 4 4 1 Dedicator of cytokinesis DUF747 PF05346.6 EKE37350.1 - 1.6e-61 208.2 25.8 2.1e-61 207.8 17.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF367 PF04034.8 EKE37351.1 - 1.9e-40 137.4 0.0 2.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EKE37351.1 - 5.9e-11 41.7 1.2 1.2e-10 40.7 0.9 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MIR PF02815.14 EKE37353.1 - 0.00052 19.6 0.0 0.00068 19.2 0.0 1.3 1 1 0 1 1 1 1 MIR domain Myelin_MBP PF01669.12 EKE37354.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Myelin basic protein DUF4298 PF14131.1 EKE37355.1 - 0.12 12.3 2.8 0.88 9.4 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) IncA PF04156.9 EKE37355.1 - 0.29 10.7 4.7 0.65 9.5 3.3 1.5 1 0 0 1 1 1 0 IncA protein DUF2935 PF11155.3 EKE37355.1 - 1.7 8.7 9.9 6.1 6.9 0.4 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF2935) DUF1825 PF08855.5 EKE37356.1 - 0.42 10.6 3.2 0.21 11.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) DENN PF02141.16 EKE37357.1 - 3.4e-28 98.6 1.2 3.4e-28 98.6 0.8 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 EKE37357.1 - 1.8e-10 40.7 2.6 4.1e-10 39.5 1.8 1.6 1 0 0 1 1 1 1 dDENN domain DUF605 PF04652.11 EKE37357.1 - 0.23 10.8 21.3 0.37 10.1 14.8 1.2 1 0 0 1 1 1 0 Vta1 like LIM PF00412.17 EKE37357.1 - 0.71 9.9 9.4 1.6 8.8 6.5 1.6 1 0 0 1 1 1 0 LIM domain Orn_Arg_deC_N PF02784.11 EKE37358.1 - 1.6e-56 191.3 0.0 2.2e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EKE37358.1 - 2.8e-21 75.3 0.0 4.1e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.15 EKE37358.1 - 1.2e-07 31.4 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DSPc PF00782.15 EKE37359.1 - 9.9e-34 115.7 0.1 1.3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EKE37359.1 - 0.00043 19.2 0.0 0.00051 19.0 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EKE37359.1 - 0.00081 18.7 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HBS1_N PF08938.5 EKE37359.1 - 0.066 13.3 0.1 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 HBS1 N-terminus NAPRTase PF04095.11 EKE37361.1 - 8.1e-49 166.1 0.2 1.3e-48 165.4 0.0 1.4 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RasGEF PF00617.14 EKE37362.1 - 3.2e-43 147.6 0.3 1.1e-42 145.9 0.2 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE37362.1 - 1.5e-12 47.5 0.1 9.1e-12 45.0 0.1 2.5 1 0 0 1 1 1 1 RasGEF N-terminal motif OmpH PF03938.9 EKE37362.1 - 0.42 10.5 11.2 0.41 10.5 5.4 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 EKE37362.1 - 0.47 9.3 12.9 1.2 8.0 9.0 1.7 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3373 PF11853.3 EKE37362.1 - 0.98 7.8 7.1 2.7 6.4 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) Fib_alpha PF08702.5 EKE37362.1 - 7.4 6.6 22.6 0.092 12.8 6.1 3.6 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family TPR_11 PF13414.1 EKE37365.1 - 4.9e-68 224.7 32.8 2.1e-18 65.7 0.8 6.2 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EKE37365.1 - 5.6e-54 177.6 42.6 2.5e-09 36.3 0.6 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EKE37365.1 - 4.4e-47 154.2 35.1 1.4e-06 27.7 0.2 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 EKE37365.1 - 2.1e-28 98.3 0.5 4.3e-06 27.2 0.0 6.3 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EKE37365.1 - 1.9e-22 78.9 19.4 3e-06 27.0 0.1 6.8 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37365.1 - 1e-20 73.8 9.0 0.00056 20.1 0.0 6.6 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EKE37365.1 - 7.5e-20 69.4 17.9 3.1e-05 23.8 0.3 8.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKE37365.1 - 2.3e-19 68.1 0.1 0.025 15.1 0.0 8.7 4 3 5 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE37365.1 - 1.3e-18 65.3 36.9 0.0021 17.7 0.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 EKE37365.1 - 1.5e-15 55.6 15.0 0.022 14.5 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EKE37365.1 - 5.2e-13 48.6 0.1 0.00013 21.7 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKE37365.1 - 4e-12 45.8 17.2 0.0017 18.1 0.1 7.4 7 1 1 8 8 8 4 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EKE37365.1 - 5.8e-10 39.1 29.2 7.1e-06 26.0 3.4 5.2 3 3 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKE37365.1 - 3.8e-05 23.8 20.6 0.45 11.0 0.0 8.2 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_3 PF07720.7 EKE37365.1 - 5.8e-05 22.7 15.8 0.17 11.6 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 EKE37365.1 - 6.8e-05 22.9 1.8 3 8.0 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKE37365.1 - 0.00021 21.1 1.4 0.93 9.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat PAZ_siRNAbind PF12212.3 EKE37365.1 - 0.006 16.1 0.0 0.034 13.7 0.0 2.3 1 0 0 1 1 1 1 Piwi/Argonaute/Zwille siRNA-binding domain MIT PF04212.13 EKE37365.1 - 0.0066 16.3 22.8 4 7.4 0.6 6.8 7 1 0 7 7 6 2 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 EKE37365.1 - 0.0088 16.2 10.1 0.72 10.0 0.1 4.5 4 1 0 4 4 4 1 Alkyl sulfatase dimerisation SHNi-TPR PF10516.4 EKE37365.1 - 0.023 13.9 10.4 2.9 7.2 0.1 6.7 9 0 0 9 9 9 0 SHNi-TPR Rapsyn_N PF10579.4 EKE37365.1 - 0.03 14.1 0.8 0.2 11.4 0.3 2.7 3 0 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region SPOB_a PF14689.1 EKE37365.1 - 0.4 10.2 4.2 4.2 7.0 0.2 3.3 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF3856 PF12968.2 EKE37365.1 - 2.1 8.1 11.9 2.7 7.8 1.3 4.8 4 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) PPR PF01535.15 EKE37365.1 - 6.8 6.9 11.9 40 4.4 0.0 6.0 6 0 0 6 6 6 0 PPR repeat HD-ZIP_N PF04618.7 EKE37365.1 - 8.7 6.9 6.2 1.6 9.2 0.4 2.5 2 1 1 3 3 2 0 HD-ZIP protein N terminus IBR PF01485.16 EKE37366.1 - 1.1e-08 34.7 33.8 5.7e-06 26.1 6.3 4.6 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EKE37366.1 - 0.0073 16.3 9.9 0.0073 16.3 6.9 5.4 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) UBA PF00627.26 EKE37366.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain HATPase_c PF02518.21 EKE37368.1 - 2.4e-05 24.0 0.2 0.00022 20.9 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.27 EKE37370.1 - 0.0015 18.3 12.0 2 8.4 0.2 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat Rav1p_C PF12234.3 EKE37370.1 - 0.011 13.8 0.6 0.016 13.4 0.4 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal Alpha-amylase PF00128.19 EKE37371.1 - 1.2e-15 57.7 4.0 2.6e-15 56.6 0.6 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Gryzun-like PF12742.2 EKE37373.1 - 3.5e-05 23.5 0.2 0.00041 20.0 0.0 2.5 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.3 EKE37373.1 - 7.1e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_2 PF07719.12 EKE37373.1 - 0.0059 16.4 0.0 0.063 13.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE37373.1 - 0.0071 16.0 1.3 0.073 12.8 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Orthoreo_P17 PF07272.6 EKE37373.1 - 0.021 14.6 0.7 0.35 10.6 0.1 2.6 2 0 0 2 2 2 0 Orthoreovirus P17 protein TPR_7 PF13176.1 EKE37373.1 - 0.079 12.7 0.0 2.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37373.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EKE37373.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKE37373.1 - 0.18 11.4 2.4 0.39 10.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DENN PF02141.16 EKE37374.1 - 4e-17 62.5 7.1 3.3e-16 59.5 4.4 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain Mycoplasma_p37 PF06646.6 EKE37374.1 - 0.0012 17.9 0.1 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 High affinity transport system protein p37 uDENN PF03456.13 EKE37374.1 - 0.0083 16.0 0.1 0.029 14.3 0.1 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EKE37374.1 - 0.0086 16.1 2.2 0.071 13.1 0.6 2.6 2 0 0 2 2 2 1 dDENN domain REV PF00424.13 EKE37375.1 - 0.57 10.1 7.4 0.25 11.2 0.3 2.3 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) YqzE PF14038.1 EKE37375.1 - 0.82 9.4 0.0 0.82 9.4 0.0 4.7 5 1 0 5 5 5 0 YqzE-like protein Cation_efflux PF01545.16 EKE37376.1 - 3.7e-24 85.3 10.4 4.6e-24 84.9 7.2 1.0 1 0 0 1 1 1 1 Cation efflux family DUF697 PF05128.7 EKE37376.1 - 0.15 11.5 0.9 0.25 10.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) DUF1129 PF06570.6 EKE37376.1 - 2.7 7.2 8.8 0.14 11.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Proteasome PF00227.21 EKE37377.1 - 1.9e-35 121.9 0.0 2.4e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF2121 PF09894.4 EKE37377.1 - 0.022 14.0 0.1 0.055 12.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) RasGAP PF00616.14 EKE37378.1 - 5.4e-15 55.5 7.7 6.2e-15 55.3 2.2 2.6 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF3535 PF12054.3 EKE37378.1 - 0.043 12.4 0.0 0.085 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) DUF3021 PF11457.3 EKE37379.1 - 0.11 12.4 3.1 0.1 12.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) RhoGEF PF00621.15 EKE37380.1 - 5.2e-42 143.7 0.4 5.2e-42 143.7 0.3 2.1 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EKE37380.1 - 1.8e-13 50.2 15.5 4.1e-13 49.0 10.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE37380.1 - 6.4e-05 23.1 2.8 8.2e-05 22.7 0.2 2.6 1 1 1 2 2 2 1 PH domain PTEN_C2 PF10409.4 EKE37381.1 - 3.3e-15 56.0 0.4 4.1e-14 52.4 0.3 2.8 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF547 PF04784.9 EKE37381.1 - 9e-10 38.4 0.0 2.7e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF547 PTPlike_phytase PF14566.1 EKE37381.1 - 0.0012 18.9 0.1 0.0049 16.9 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EKE37381.1 - 0.011 15.9 0.1 0.055 13.7 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Peptidase_M16 PF00675.15 EKE37382.1 - 1.9e-14 53.6 0.0 2.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EKE37382.1 - 0.023 14.3 1.1 0.046 13.4 0.8 1.6 1 0 0 1 1 1 0 Peptidase M16 inactive domain Nitroreductase PF00881.19 EKE37383.1 - 5.9e-13 48.9 0.5 0.00027 20.8 0.0 3.5 3 1 1 4 4 4 3 Nitroreductase family TM1586_NiRdase PF14512.1 EKE37383.1 - 0.0045 16.2 0.1 0.095 11.8 0.0 2.3 2 0 0 2 2 2 1 Putative TM nitroreductase RNA_helicase PF00910.17 EKE37386.1 - 0.0013 18.8 0.3 0.0039 17.3 0.1 1.9 1 1 1 2 2 2 1 RNA helicase Hpr_kinase_C PF07475.7 EKE37386.1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PSRP-3_Ycf65 PF04839.8 EKE37386.1 - 0.14 12.2 0.3 0.36 10.9 0.2 1.7 1 1 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) TPR_11 PF13414.1 EKE37387.1 - 3.8e-31 106.5 0.7 6.9e-08 32.0 0.0 5.6 4 1 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 EKE37387.1 - 9.2e-27 90.7 0.7 0.0034 17.1 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 EKE37387.1 - 1.9e-23 81.0 2.0 0.0003 20.2 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EKE37387.1 - 7.7e-16 56.9 0.1 0.07 13.3 0.0 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE37387.1 - 1.1e-14 52.9 1.1 0.25 11.2 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE37387.1 - 5.1e-14 52.5 0.1 0.026 15.1 0.0 5.4 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKE37387.1 - 3.9e-12 45.6 0.1 0.75 10.6 0.0 6.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EKE37387.1 - 7.4e-12 45.0 2.2 0.077 12.9 0.0 5.6 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 EKE37387.1 - 3.3e-11 42.8 0.0 0.0053 16.5 0.0 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37387.1 - 4.9e-10 39.6 1.5 0.064 13.6 0.0 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EKE37387.1 - 0.00013 22.0 0.7 0.18 11.9 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EKE37387.1 - 0.00033 20.2 0.1 25 4.9 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE37387.1 - 0.00075 19.7 3.0 0.34 11.4 0.0 6.0 9 0 0 9 9 7 1 Tetratricopeptide repeat UBA_4 PF14555.1 EKE37387.1 - 0.0026 17.2 0.1 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 UBA-like domain Ras PF00071.17 EKE37388.1 - 1.1e-06 28.1 0.7 1.4e-06 27.8 0.5 1.1 1 0 0 1 1 1 1 Ras family Baculo_DNA_bind PF04786.7 EKE37388.1 - 0.038 13.1 0.1 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 ssDNA binding protein MMR_HSR1 PF01926.18 EKE37388.1 - 0.094 12.6 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RabGAP-TBC PF00566.13 EKE37389.1 - 2.4e-34 118.6 10.1 3.3e-34 118.2 7.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TIP49 PF06068.8 EKE37390.1 - 1e-160 534.8 8.1 1.2e-160 534.6 5.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EKE37390.1 - 8.8e-10 38.8 0.9 2.1e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE37390.1 - 2.6e-09 37.3 0.1 1.7e-07 31.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EKE37390.1 - 2.7e-08 33.1 1.5 1.5e-05 24.1 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EKE37390.1 - 4.6e-07 29.6 1.4 0.00057 19.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKE37390.1 - 1.5e-06 28.3 0.6 0.023 14.8 0.1 2.6 2 1 0 2 2 2 2 AAA domain DnaB_C PF03796.10 EKE37390.1 - 1.5e-05 23.9 0.1 3.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.1 EKE37390.1 - 4.1e-05 23.0 0.1 9e-05 21.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EKE37390.1 - 4.1e-05 22.8 0.5 0.0015 17.7 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EKE37390.1 - 0.00038 20.1 0.1 0.0031 17.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EKE37390.1 - 0.00051 19.1 0.1 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EKE37390.1 - 0.00093 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 EKE37390.1 - 0.0013 18.3 0.1 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EKE37390.1 - 0.0014 18.1 0.1 0.55 9.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 EKE37390.1 - 0.0017 19.1 0.1 0.0089 16.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EKE37390.1 - 0.0026 17.6 0.0 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EKE37390.1 - 0.0037 16.3 0.1 0.008 15.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EKE37390.1 - 0.0051 16.4 0.4 0.021 14.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKE37390.1 - 0.0089 16.3 0.2 0.018 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EKE37390.1 - 0.015 14.7 0.1 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EKE37390.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EKE37390.1 - 0.058 12.9 0.2 0.085 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EKE37390.1 - 0.071 12.2 0.4 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ResIII PF04851.10 EKE37390.1 - 0.078 12.7 0.2 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sipho_tail PF05709.6 EKE37390.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein CbiA PF01656.18 EKE37390.1 - 0.13 11.6 1.7 0.29 10.5 1.2 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 EKE37391.1 - 1.5e-93 309.9 0.0 2e-45 154.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKE37391.1 - 9.4e-15 54.2 0.0 3e-07 29.7 0.0 2.8 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKE37391.1 - 3.7e-13 49.7 3.4 0.00022 21.3 0.4 5.1 2 2 1 4 4 4 2 AAA domain AAA_5 PF07728.9 EKE37391.1 - 3.4e-12 46.2 0.1 1.8e-05 24.4 0.0 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKE37391.1 - 3.9e-12 46.5 4.8 9.5e-06 25.7 0.3 3.8 3 2 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.9 EKE37391.1 - 4.9e-12 46.0 0.0 0.00011 22.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EKE37391.1 - 8.4e-12 45.9 0.1 0.00022 22.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EKE37391.1 - 7e-11 42.1 0.0 0.00024 21.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EKE37391.1 - 2.9e-10 40.0 1.3 0.069 12.8 0.1 4.5 2 2 1 3 3 3 3 NACHT domain AAA_33 PF13671.1 EKE37391.1 - 4e-10 39.7 0.0 0.00017 21.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKE37391.1 - 1.3e-09 37.7 5.3 0.18 11.2 0.0 4.4 2 2 2 4 4 4 4 AAA domain Zeta_toxin PF06414.7 EKE37391.1 - 2.4e-09 36.5 0.0 0.0018 17.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 EKE37391.1 - 2.5e-09 36.8 0.0 0.0022 17.4 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EKE37391.1 - 8.4e-09 35.5 0.0 0.0014 18.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EKE37391.1 - 4e-08 32.8 0.5 0.0091 15.7 0.1 3.3 3 0 0 3 3 2 2 Part of AAA domain AAA_18 PF13238.1 EKE37391.1 - 9.8e-08 32.3 0.0 0.018 15.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EKE37391.1 - 5.2e-07 29.7 0.2 0.027 14.4 0.0 2.9 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.8 EKE37391.1 - 6.5e-07 28.4 0.0 0.0018 17.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 EKE37391.1 - 1.3e-06 27.6 1.2 0.018 14.2 0.1 3.0 3 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKE37391.1 - 1.8e-06 27.5 0.0 0.014 14.9 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKE37391.1 - 2.1e-06 27.6 0.0 0.52 9.9 0.0 4.2 2 2 1 3 3 3 2 Archaeal ATPase Viral_helicase1 PF01443.13 EKE37391.1 - 4.1e-06 26.4 0.0 0.099 12.1 0.0 2.6 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EKE37391.1 - 4.9e-06 26.8 0.0 0.014 15.7 0.0 3.0 2 0 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EKE37391.1 - 5.6e-06 26.4 0.0 0.048 13.7 0.0 3.2 2 1 1 3 3 3 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EKE37391.1 - 8.4e-06 25.3 0.1 0.39 10.1 0.0 3.7 3 1 0 3 3 2 2 Sigma-54 interaction domain Rad17 PF03215.10 EKE37391.1 - 2.6e-05 23.1 0.0 0.13 10.9 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EKE37391.1 - 5.4e-05 22.8 0.1 0.043 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EKE37391.1 - 6.2e-05 22.2 1.4 0.24 10.4 0.0 4.1 3 1 1 4 4 4 1 KaiC DUF815 PF05673.8 EKE37391.1 - 0.00026 20.0 0.0 0.19 10.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EKE37391.1 - 0.00031 19.7 0.0 0.65 8.8 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 SKI PF01202.17 EKE37391.1 - 0.00035 20.4 0.1 0.78 9.5 0.0 2.9 2 0 0 2 2 2 2 Shikimate kinase Bac_DnaA PF00308.13 EKE37391.1 - 0.00036 20.2 0.0 1.8 8.1 0.0 3.5 2 2 0 2 2 2 2 Bacterial dnaA protein NTPase_1 PF03266.10 EKE37391.1 - 0.00054 19.7 0.3 0.58 9.8 0.0 3.8 4 0 0 4 4 4 1 NTPase UPF0079 PF02367.12 EKE37391.1 - 0.00061 19.4 0.1 0.79 9.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EKE37391.1 - 0.00078 18.3 0.1 0.36 9.6 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain Cytidylate_kin2 PF13189.1 EKE37391.1 - 0.00078 19.3 0.1 0.3 10.9 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase-like family PhoH PF02562.11 EKE37391.1 - 0.0012 18.1 0.4 1.8 7.7 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein Vps4_C PF09336.5 EKE37391.1 - 0.0022 17.8 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_11 PF13086.1 EKE37391.1 - 0.0042 16.7 0.0 1.9 8.0 0.0 2.7 2 2 0 2 2 2 1 AAA domain ResIII PF04851.10 EKE37391.1 - 0.0059 16.4 0.0 3.3 7.4 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EKE37391.1 - 0.015 14.7 1.1 9.8 5.5 0.0 3.8 2 2 1 3 3 3 0 AAA-like domain Zot PF05707.7 EKE37391.1 - 0.017 14.6 0.0 13 5.1 0.0 3.8 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) ATP-synt_ab PF00006.20 EKE37391.1 - 0.02 14.4 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 EKE37391.1 - 0.021 13.7 0.0 5.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EKE37391.1 - 0.027 14.0 0.0 3.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.1 EKE37391.1 - 0.031 13.8 0.0 3.4 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EKE37391.1 - 0.039 12.9 0.0 1.9 7.3 0.0 2.8 2 2 0 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.4 EKE37391.1 - 0.04 13.3 0.0 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.5 EKE37391.1 - 0.044 12.9 0.0 3.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 HD_assoc PF13286.1 EKE37391.1 - 0.06 13.6 0.1 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Phosphohydrolase-associated domain AFG1_ATPase PF03969.11 EKE37391.1 - 0.086 11.6 0.8 5.9 5.5 0.0 3.2 4 0 0 4 4 4 0 AFG1-like ATPase Torsin PF06309.6 EKE37391.1 - 0.11 12.3 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Torsin ADK PF00406.17 EKE37391.1 - 0.27 11.0 1.5 28 4.5 0.0 2.9 3 0 0 3 3 3 0 Adenylate kinase IBR PF01485.16 EKE37392.1 - 1.2e-08 34.6 11.3 1.2e-08 34.6 7.8 2.8 2 0 0 2 2 2 1 IBR domain PARP PF00644.15 EKE37392.1 - 6.3e-08 32.2 0.2 1.1e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Transpos_assoc PF13963.1 EKE37392.1 - 0.024 14.6 2.0 0.024 14.6 1.4 2.3 2 0 0 2 2 2 0 Transposase-associated domain FYVE_2 PF02318.11 EKE37392.1 - 0.097 12.5 6.4 0.042 13.7 2.6 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger NAD_synthase PF02540.12 EKE37393.1 - 7.1e-38 129.8 0.0 8.3e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 EKE37393.1 - 0.009 14.6 0.0 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EKE37393.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Arf PF00025.16 EKE37394.1 - 3.2e-32 111.1 0.0 1.4e-30 105.7 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EKE37394.1 - 6.9e-07 28.2 0.5 2.4e-05 23.2 0.0 2.2 1 1 0 2 2 2 1 G-protein alpha subunit Ras PF00071.17 EKE37394.1 - 3.4e-05 23.2 0.0 5.6e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EKE37394.1 - 0.0011 18.1 0.0 0.0027 16.8 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EKE37394.1 - 0.0045 17.4 0.0 0.0071 16.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EKE37394.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fe_hyd_lg_C PF02906.9 EKE37395.1 - 1.2e-77 260.9 2.9 1.6e-77 260.6 2.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 EKE37395.1 - 2e-09 37.3 0.8 3.1e-09 36.7 0.5 1.3 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4 PF00037.22 EKE37395.1 - 3.3e-09 35.9 11.1 2.9e-06 26.6 1.4 3.3 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EKE37395.1 - 1.1e-08 35.2 20.4 2.3e-07 31.0 7.4 3.7 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EKE37395.1 - 3.4e-08 33.9 3.0 0.0035 17.8 0.1 3.1 3 0 0 3 3 2 2 4Fe-4S single cluster domain Fer4_10 PF13237.1 EKE37395.1 - 9.2e-07 28.5 19.9 7.4e-06 25.6 7.5 3.3 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE37395.1 - 1.1e-06 28.2 17.6 0.00015 21.4 1.2 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 EKE37395.1 - 2.6e-06 27.5 8.3 2.6e-06 27.5 5.8 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKE37395.1 - 6.4e-06 26.1 8.8 6.4e-06 26.1 6.1 3.0 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EKE37395.1 - 5.2e-05 23.5 19.6 6.5e-05 23.1 6.5 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE37395.1 - 0.00027 20.6 1.4 0.00027 20.6 1.0 3.6 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EKE37395.1 - 0.00031 20.5 5.0 0.0019 18.0 0.3 3.2 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EKE37395.1 - 0.0064 17.2 18.4 0.0091 16.7 7.1 3.4 3 1 2 5 5 4 3 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 EKE37395.1 - 0.0075 16.6 0.8 0.0075 16.6 0.5 3.2 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.1 EKE37395.1 - 0.34 10.8 0.0 0.34 10.8 0.0 4.1 5 0 0 5 5 4 0 4Fe-4S dicluster domain Fer4_13 PF13370.1 EKE37395.1 - 2.2 8.7 12.8 6.3 7.2 2.2 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain CPSF100_C PF13299.1 EKE37396.1 - 0.14 12.3 3.0 0.22 11.6 2.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Med4 PF10018.4 EKE37396.1 - 0.23 10.8 6.8 0.077 12.3 2.0 2.0 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 YccV-like PF08755.6 EKE37396.1 - 0.68 9.8 2.6 1.4 8.8 0.5 2.2 1 1 1 2 2 2 0 Hemimethylated DNA-binding protein YccV like Snf7 PF03357.16 EKE37396.1 - 2.8 7.3 11.3 0.98 8.7 5.8 1.7 2 0 0 2 2 2 0 Snf7 DENN PF02141.16 EKE37397.1 - 1.4e-12 47.7 2.0 8.5e-12 45.1 0.7 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 EKE37397.1 - 2e-10 40.5 0.8 2e-10 40.5 0.5 2.2 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 EKE37397.1 - 0.00028 20.8 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 uDENN domain Thioredoxin_7 PF13899.1 EKE37398.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like Prefoldin_2 PF01920.15 EKE37399.1 - 2.9e-20 72.0 8.6 3.2e-20 71.8 6.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EKE37399.1 - 4e-06 26.4 5.2 7.2e-06 25.6 0.2 2.1 1 1 0 2 2 2 1 Prefoldin subunit Med9 PF07544.8 EKE37399.1 - 0.00014 21.5 1.9 0.00037 20.1 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DASH_Dad3 PF08656.5 EKE37399.1 - 0.0033 17.0 4.1 0.008 15.8 0.8 2.1 2 0 0 2 2 2 1 DASH complex subunit Dad3 M_domain PF12938.2 EKE37399.1 - 0.011 15.5 3.0 0.013 15.3 2.1 1.1 1 0 0 1 1 1 0 M domain of GW182 DUF4164 PF13747.1 EKE37399.1 - 0.027 14.6 2.2 0.98 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF948 PF06103.6 EKE37399.1 - 0.027 14.3 3.8 1.6 8.6 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG17 PF04108.7 EKE37399.1 - 0.032 13.0 2.4 0.045 12.5 1.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 BLYB PF05289.6 EKE37399.1 - 0.038 13.7 1.5 0.11 12.2 1.0 1.8 1 1 0 1 1 1 0 Borrelia hemolysin accessory protein TSA PF03249.8 EKE37399.1 - 0.039 12.5 0.8 0.041 12.4 0.5 1.2 1 0 0 1 1 1 0 Type specific antigen Transcrip_act PF04949.8 EKE37399.1 - 0.049 13.2 0.6 0.072 12.7 0.4 1.3 1 1 0 1 1 1 0 Transcriptional activator AAA_13 PF13166.1 EKE37399.1 - 0.055 11.9 3.4 0.064 11.7 2.3 1.0 1 0 0 1 1 1 0 AAA domain Prefoldin_3 PF13758.1 EKE37399.1 - 0.061 13.0 1.4 0.19 11.5 0.9 1.9 1 1 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 EKE37399.1 - 0.094 12.3 4.9 0.14 11.7 3.4 1.3 1 1 0 1 1 1 0 IncA protein DASH_Dad1 PF08649.5 EKE37399.1 - 0.13 11.9 0.9 0.33 10.6 0.5 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad1 Dna2 PF08696.6 EKE37399.1 - 0.14 11.4 1.2 0.15 11.3 0.4 1.4 1 1 0 1 1 1 0 DNA replication factor Dna2 Snapin_Pallidin PF14712.1 EKE37399.1 - 0.15 12.3 8.4 2 8.7 0.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DUF3847 PF12958.2 EKE37399.1 - 0.23 11.2 2.3 0.43 10.3 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) FliD_C PF07195.7 EKE37399.1 - 0.24 10.6 0.1 0.24 10.6 0.1 1.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ApoLp-III PF07464.6 EKE37399.1 - 0.34 10.9 5.8 0.17 11.8 0.5 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF342 PF03961.8 EKE37399.1 - 0.39 9.0 5.3 0.48 8.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2203 PF09969.4 EKE37399.1 - 0.45 10.7 2.2 0.84 9.8 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Baculo_PEP_C PF04513.7 EKE37399.1 - 0.46 10.2 3.4 2.2 8.1 2.4 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.8 EKE37399.1 - 0.6 10.8 3.9 7.6 7.3 0.2 2.1 2 0 0 2 2 2 0 Occludin homology domain HAUS-augmin3 PF14932.1 EKE37399.1 - 0.66 9.1 6.7 2.1 7.4 4.7 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 TPR_MLP1_2 PF07926.7 EKE37399.1 - 0.8 9.4 6.1 3 7.5 4.2 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EKE37399.1 - 1 9.1 4.1 2 8.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 EKE37399.1 - 1.1 9.2 9.0 0.63 10.0 0.4 2.1 2 0 0 2 2 2 0 FlxA-like protein WXG100 PF06013.7 EKE37399.1 - 1.1 9.2 5.2 9.2 6.3 1.4 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Spc7 PF08317.6 EKE37399.1 - 1.7 7.2 8.0 6.6 5.2 5.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2681 PF10883.3 EKE37399.1 - 2 8.6 8.0 0.42 10.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Fib_alpha PF08702.5 EKE37399.1 - 2.5 8.2 7.2 4.9 7.2 5.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.1 EKE37399.1 - 2.6 8.1 7.2 0.77 9.8 0.1 2.4 2 1 0 2 2 2 0 Syntaxin-like protein FNIP PF05725.7 EKE37402.1 - 0.03 14.2 0.7 0.03 14.2 0.5 7.3 7 2 1 8 8 8 0 FNIP Repeat DUF4257 PF14074.1 EKE37404.1 - 0.0045 16.6 0.0 0.0078 15.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4257) Mpv17_PMP22 PF04117.7 EKE37404.1 - 0.011 15.3 0.7 0.017 14.7 0.5 1.3 1 0 0 1 1 1 0 Mpv17 / PMP22 family SH PF01445.12 EKE37404.1 - 0.012 15.2 0.5 0.019 14.5 0.1 1.5 1 1 1 2 2 2 0 Viral small hydrophobic protein NfeD PF01957.13 EKE37404.1 - 0.015 15.4 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding RhoGEF PF00621.15 EKE37406.1 - 6.9e-21 74.9 8.6 1.9e-20 73.5 6.0 1.8 1 0 0 1 1 1 1 RhoGEF domain Maelstrom PF13017.1 EKE37407.1 - 9.9e-38 129.7 4.1 9.9e-38 129.7 2.8 2.6 2 2 1 3 3 3 1 piRNA pathway germ-plasm component RNase_T PF00929.19 EKE37407.1 - 0.0057 16.9 0.3 0.12 12.6 0.2 2.8 1 1 0 1 1 1 1 Exonuclease LIN37 PF15306.1 EKE37407.1 - 0.2 11.6 4.6 0.42 10.5 3.2 1.5 1 0 0 1 1 1 0 LIN37 Porin_4 PF13609.1 EKE37409.1 - 3.4e-05 23.5 81.6 0.00021 20.9 9.0 4.6 1 1 4 5 5 5 3 Gram-negative porin OMP_b-brl_3 PF14905.1 EKE37409.1 - 8.3e-05 21.4 97.0 0.0024 16.6 16.6 5.0 1 1 3 4 4 4 3 Outer membrane protein beta-barrel family DUF1597 PF07642.6 EKE37409.1 - 0.13 11.2 62.0 0.036 13.0 10.4 5.7 1 1 2 3 3 3 0 Outer membrane protein family (DUF1597) Ctr PF04145.10 EKE37409.1 - 0.3 11.1 0.1 0.3 11.1 0.0 2.4 2 1 0 2 2 2 0 Ctr copper transporter family OMP_b-brl PF13505.1 EKE37409.1 - 2.2 8.1 81.1 0.015 15.2 15.5 5.0 1 1 3 4 4 4 0 Outer membrane protein beta-barrel domain Pex16 PF08610.5 EKE37409.1 - 6.5 5.6 6.7 13 4.6 4.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) LRR_5 PF13306.1 EKE37410.1 - 8.6e-22 77.2 23.5 2.9e-14 52.8 5.0 3.7 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37410.1 - 5.2e-12 45.3 8.9 2.5e-05 23.9 0.2 4.6 4 1 1 5 5 5 3 Leucine rich repeat Glyco_hydro_14 PF01373.12 EKE37411.1 - 4.3e-109 364.9 8.0 4.9e-109 364.7 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_42 PF02449.10 EKE37411.1 - 0.081 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase DUF3781 PF12636.2 EKE37413.1 - 8 6.5 10.9 0.56 10.2 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3781) E1-E2_ATPase PF00122.15 EKE37414.1 - 1e-27 96.6 1.7 1.4e-27 96.2 0.3 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EKE37414.1 - 1.1e-14 53.6 0.0 2.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FtsX PF02687.16 EKE37414.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family LRR_5 PF13306.1 EKE37415.1 - 2e-225 735.6 157.5 6.1e-35 119.7 13.3 9.6 4 4 4 9 9 9 9 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37415.1 - 2.1e-76 251.5 62.3 1e-06 28.4 0.5 20.8 8 5 21 29 29 29 25 Leucine rich repeat Clathrin_bdg PF15045.1 EKE37415.1 - 0.07 12.6 0.0 0.8 9.2 0.0 2.6 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking PTCB-BRCT PF12738.2 EKE37416.1 - 6e-07 29.2 0.1 1.7e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKE37416.1 - 0.002 18.2 6.6 0.0056 16.7 0.3 3.5 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain DOG1 PF14144.1 EKE37416.1 - 0.081 12.9 0.4 12 6.0 0.0 3.1 2 1 1 3 3 3 0 Seed dormancy control NAM-associated PF14303.1 EKE37416.1 - 2.6 8.3 28.0 1.1 9.5 12.6 2.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF3153 PF11353.3 EKE37416.1 - 4 6.8 6.7 1.3 8.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) SPRY PF00622.23 EKE37417.1 - 5.1e-14 52.4 0.5 8.1e-14 51.7 0.3 1.3 1 0 0 1 1 1 1 SPRY domain Clathrin_lg_ch PF01086.12 EKE37418.1 - 0.0037 17.2 17.0 0.0042 17.0 11.8 1.1 1 0 0 1 1 1 1 Clathrin light chain Asp-B-Hydro_N PF05279.6 EKE37418.1 - 3.5 7.4 25.0 4.4 7.0 17.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.20 EKE37419.1 - 1e-33 116.6 0.1 1.2e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37419.1 - 3.5e-15 55.7 0.0 4.5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 EKE37419.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family APH PF01636.18 EKE37419.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L14e PF01929.12 EKE37420.1 - 8e-15 54.9 1.2 1.1e-14 54.4 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EKE37420.1 - 0.0036 16.9 0.0 0.0081 15.8 0.0 1.7 1 0 0 1 1 1 1 KOW motif Ribosomal_L35p PF01632.14 EKE37420.1 - 0.022 14.6 0.3 0.041 13.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L35 Cucumo_coat PF00760.13 EKE37420.1 - 0.059 12.3 0.1 0.071 12.0 0.1 1.1 1 0 0 1 1 1 0 Cucumovirus coat protein RhoGEF PF00621.15 EKE37423.1 - 4.3e-26 91.8 8.8 4.3e-26 91.8 6.1 1.9 2 0 0 2 2 2 1 RhoGEF domain IQ PF00612.22 EKE37423.1 - 0.015 14.8 0.1 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Utp12 PF04003.7 EKE37424.1 - 0.0025 17.6 0.6 0.0068 16.2 0.4 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family LRR_5 PF13306.1 EKE37425.1 - 4.9e-45 152.3 5.1 1.4e-29 102.4 5.5 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37425.1 - 1.3e-17 63.2 1.0 8.8e-07 28.5 0.5 4.4 1 1 3 4 4 4 3 Leucine rich repeat NUDIX PF00293.23 EKE37426.1 - 1.4e-20 73.3 0.0 1.8e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DZR PF12773.2 EKE37426.1 - 0.016 14.9 0.6 0.024 14.4 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.1 EKE37426.1 - 0.052 13.0 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-C2H2_3 PF13878.1 EKE37426.1 - 0.054 13.0 1.9 0.083 12.4 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-ribbon_3 PF13248.1 EKE37426.1 - 0.065 12.4 4.8 0.14 11.3 3.3 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EKE37426.1 - 0.1 12.3 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type TF_Zn_Ribbon PF08271.7 EKE37426.1 - 0.13 11.6 2.0 0.31 10.3 1.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding NUDIX_4 PF14815.1 EKE37426.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Ribosomal_L37e PF01907.14 EKE37426.1 - 0.19 11.5 1.8 0.37 10.6 1.3 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e DUF2082 PF09855.4 EKE37426.1 - 0.19 11.5 3.5 2.2 8.2 0.3 2.4 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 EKE37426.1 - 0.5 10.1 5.0 5.2 6.8 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.11 EKE37426.1 - 0.72 9.5 4.0 1.4 8.6 2.8 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DUF3797 PF12677.2 EKE37426.1 - 2.3 7.8 7.7 21 4.8 4.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zinc_ribbon_2 PF13240.1 EKE37426.1 - 6.9 6.2 9.6 1.6 8.2 1.8 2.3 1 1 1 2 2 2 0 zinc-ribbon domain CBFB_NFYA PF02045.10 EKE37427.1 - 3.9e-19 68.9 8.0 5.8e-19 68.3 5.5 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B RPAP2_Rtr1 PF04181.8 EKE37427.1 - 0.46 10.5 2.3 0.95 9.5 1.6 1.6 1 1 0 1 1 1 0 Rtr1/RPAP2 family VPS9 PF02204.13 EKE37428.1 - 0.012 15.6 0.5 0.012 15.6 0.4 2.1 2 1 1 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain Abhydrolase_5 PF12695.2 EKE37429.1 - 2e-05 24.3 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.7 EKE37429.1 - 0.00082 18.2 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) SAM_2 PF07647.12 EKE37429.1 - 0.0028 17.4 0.1 0.031 14.1 0.0 2.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EKE37429.1 - 0.014 15.5 0.3 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Ndr PF03096.9 EKE37429.1 - 0.016 13.6 0.0 0.028 12.9 0.0 1.3 1 0 0 1 1 1 0 Ndr family SNARE PF05739.14 EKE37430.1 - 1.2e-05 24.8 1.8 1.5e-05 24.6 1.3 1.1 1 0 0 1 1 1 1 SNARE domain Glyco_hydro_38C PF07748.8 EKE37430.1 - 0.0079 15.0 0.7 0.0092 14.8 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Rifin_STEVOR PF02009.11 EKE37430.1 - 0.0092 15.6 1.0 0.0097 15.5 0.7 1.0 1 0 0 1 1 1 1 Rifin/stevor family Prominin PF05478.6 EKE37430.1 - 0.014 12.9 0.9 0.016 12.8 0.6 1.0 1 0 0 1 1 1 0 Prominin PgaD PF13994.1 EKE37430.1 - 0.061 12.8 0.1 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein Amnionless PF14828.1 EKE37430.1 - 0.062 11.7 0.1 0.062 11.7 0.1 1.1 1 0 0 1 1 1 0 Amnionless YflT PF11181.3 EKE37430.1 - 0.14 12.3 2.4 0.2 11.8 1.6 1.3 1 1 0 1 1 1 0 Heat induced stress protein YflT eIF3_N PF09440.5 EKE37430.1 - 0.24 11.5 2.2 0.27 11.4 1.5 1.1 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF912 PF06024.7 EKE37430.1 - 0.85 9.7 6.6 2.8 8.0 4.6 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 EKE37430.1 - 1.1 9.1 5.0 0.33 10.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Pkinase PF00069.20 EKE37432.1 - 1.5e-52 178.3 0.6 1.8e-52 178.0 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37432.1 - 4.8e-32 111.0 0.1 6.1e-32 110.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37432.1 - 0.00031 19.7 0.0 0.0031 16.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKE37432.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EKE37432.1 - 0.0026 16.6 0.1 0.0026 16.6 0.1 2.4 3 0 0 3 3 3 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 EKE37432.1 - 0.073 12.4 0.2 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EKE37432.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.5 1 1 0 1 1 1 0 RIO1 family PTPLA PF04387.9 EKE37434.1 - 8.2e-46 155.4 9.7 8.2e-46 155.4 6.7 1.8 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA TMEMspv1-c74-12 PF11044.3 EKE37434.1 - 1.2 8.7 4.7 4.3 6.9 0.1 2.9 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein HEAT_EZ PF13513.1 EKE37435.1 - 0.00073 19.9 2.9 0.094 13.2 0.0 4.9 3 1 4 7 7 7 1 HEAT-like repeat NAD_kinase PF01513.16 EKE37435.1 - 0.026 13.3 0.1 0.046 12.5 0.1 1.3 1 0 0 1 1 1 0 ATP-NAD kinase HEAT PF02985.17 EKE37435.1 - 0.11 12.6 5.6 16 5.8 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat UNC45-central PF11701.3 EKE37435.1 - 0.39 10.3 8.7 5.7 6.5 0.2 4.4 3 2 1 4 4 4 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EKE37435.1 - 2.2 7.5 6.5 1.1 8.5 0.5 3.2 3 1 0 3 3 3 0 CLASP N terminal LRR_5 PF13306.1 EKE37436.1 - 3.2e-132 434.3 102.6 2.6e-28 98.3 7.5 7.2 3 2 3 7 7 7 7 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37436.1 - 1.1e-57 191.5 33.8 2.2e-09 36.9 1.2 12.1 5 4 8 13 13 13 12 Leucine rich repeat LRR_4 PF12799.2 EKE37436.1 - 0.1 12.2 13.2 14 5.4 2.0 6.2 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) Xpo1 PF08389.7 EKE37437.1 - 0.044 13.6 0.3 0.053 13.4 0.2 1.2 1 0 0 1 1 1 0 Exportin 1-like protein zf-C3HC4_3 PF13920.1 EKE37439.1 - 4.8e-15 54.9 16.6 4.8e-15 54.9 11.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE37439.1 - 4e-06 26.7 19.9 4e-06 26.7 13.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EKE37439.1 - 0.013 15.0 10.4 0.022 14.3 6.4 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 EKE37439.1 - 0.017 14.8 17.6 0.017 14.8 12.2 2.2 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.1 EKE37439.1 - 0.026 14.3 15.6 0.026 14.3 10.8 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 EKE37439.1 - 0.32 10.7 15.7 2.2 8.0 6.1 2.8 2 0 0 2 2 2 0 RING-type zinc-finger EI24 PF07264.6 EKE37440.1 - 6.8e-05 22.3 16.1 0.00014 21.3 11.2 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Vma12 PF11712.3 EKE37440.1 - 0.094 12.4 2.2 7.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GP41 PF00517.12 EKE37440.1 - 0.86 9.1 6.9 0.11 11.9 0.8 2.2 2 0 0 2 2 2 0 Retroviral envelope protein A_deaminase PF00962.17 EKE37441.1 - 3.1e-133 443.7 0.2 4.5e-76 255.9 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase zf-B_box PF00643.19 EKE37441.1 - 1.3e-05 24.9 7.6 4.8e-05 23.1 5.2 2.1 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 EKE37441.1 - 0.00054 19.7 3.3 0.0014 18.4 2.3 1.8 1 0 0 1 1 1 1 IBR domain RHH_1 PF01402.16 EKE37441.1 - 0.097 12.5 0.0 2.4 8.2 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family CDC45 PF02724.9 EKE37442.1 - 0.56 8.1 24.4 0.59 8.1 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EKE37442.1 - 0.94 8.4 33.3 1.1 8.3 23.1 1.1 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 EKE37442.1 - 1.3 8.1 21.1 1.5 8.0 14.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4551 PF15087.1 EKE37442.1 - 4.8 5.4 10.7 6.7 4.9 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GAGA_bind PF06217.7 EKE37442.1 - 7.3 6.4 9.6 9.1 6.1 6.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.7 EKE37442.1 - 7.6 4.3 40.6 9 4.0 28.1 1.2 1 0 0 1 1 1 0 Nop14-like family Herpes_DNAp_acc PF04929.7 EKE37442.1 - 8.5 5.2 10.5 10 4.9 7.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FHA PF00498.21 EKE37443.1 - 5.6e-13 48.8 0.1 9.1e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 FHA domain TLD PF07534.11 EKE37444.1 - 2.4e-05 24.3 0.8 4e-05 23.6 0.5 1.4 1 0 0 1 1 1 1 TLD DUF1492 PF07374.6 EKE37444.1 - 0.59 10.2 9.9 0.39 10.8 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) AMP-binding PF00501.23 EKE37446.1 - 3.4e-73 246.4 0.0 4.5e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_C32 PF05411.7 EKE37446.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase Xpo1 PF08389.7 EKE37447.1 - 6.4e-13 48.8 1.9 6.4e-13 48.8 1.3 3.6 3 1 0 3 3 3 1 Exportin 1-like protein CPSF_A PF03178.10 EKE37449.1 - 5.4e-37 127.5 1.4 5.4e-37 127.5 1.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region PQQ_3 PF13570.1 EKE37449.1 - 0.13 12.5 2.0 13 6.2 0.0 3.7 5 0 0 5 5 5 0 PQQ-like domain PGBA_N PF15436.1 EKE37450.1 - 0.0039 16.5 1.2 0.0039 16.5 0.8 2.2 2 1 1 3 3 3 1 Plasminogen-binding protein pgbA N-terminal RhoGAP PF00620.22 EKE37451.1 - 1.7e-17 63.4 0.3 6e-17 61.6 0.2 1.9 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 EKE37451.1 - 0.017 14.8 16.3 0.038 13.7 11.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EcsB PF05975.7 EKE37453.1 - 0.078 11.4 2.0 0.082 11.3 1.4 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Myotub-related PF06602.9 EKE37454.1 - 8.7e-95 317.4 1.0 1.4e-94 316.7 0.7 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PH PF00169.24 EKE37454.1 - 0.007 16.5 1.5 0.017 15.3 0.1 2.3 2 0 0 2 2 2 1 PH domain DSPc PF00782.15 EKE37454.1 - 0.0078 15.7 0.3 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EKE37454.1 - 0.031 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PH PF00169.24 EKE37456.1 - 6e-10 39.2 0.1 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKE37456.1 - 3.7e-05 23.9 0.1 8.5e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RRM_1 PF00076.17 EKE37457.1 - 1.9e-07 30.6 0.1 4.7e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37457.1 - 1.4e-05 25.0 0.1 3.4e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EKE37457.1 - 0.0015 18.0 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) NDUF_B12 PF08122.7 EKE37459.1 - 1.4 8.7 5.8 7.5 6.3 0.9 2.4 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family HXXEE PF13787.1 EKE37459.1 - 1.9 8.8 10.6 3.2 8.1 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif VIT1 PF01988.14 EKE37459.1 - 4.6 6.6 8.3 5.7 6.3 5.8 1.2 1 0 0 1 1 1 0 VIT family FA_desaturase PF00487.19 EKE37459.1 - 5.6 6.3 8.4 6.3 6.1 5.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase RseC_MucC PF04246.7 EKE37459.1 - 7.8 6.0 11.8 20 4.7 8.1 1.7 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Ribophorin_II PF05817.9 EKE37459.1 - 8.2 4.4 10.1 9.4 4.3 7.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II MIG-14_Wnt-bd PF06664.7 EKE37460.1 - 1.2e-36 126.1 43.4 1.6e-36 125.7 30.1 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion zf-C2H2_4 PF13894.1 EKE37461.1 - 0.0001 22.3 1.4 0.0019 18.3 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EKE37461.1 - 0.00078 18.8 3.9 0.4 10.1 0.0 3.6 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-Di19 PF05605.7 EKE37461.1 - 0.0016 18.4 4.7 0.0034 17.4 0.0 2.6 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EKE37461.1 - 0.0048 17.1 3.1 0.034 14.4 0.0 2.9 2 1 0 2 2 2 1 Zinc finger, C2H2 type DUF972 PF06156.8 EKE37461.1 - 0.33 11.3 8.8 0.55 10.6 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF603 PF04645.7 EKE37461.1 - 0.34 10.8 4.0 0.55 10.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Proteasome PF00227.21 EKE37462.1 - 1e-44 152.1 0.0 1.2e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Lipase_3 PF01764.20 EKE37463.1 - 6.1e-06 25.9 0.1 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) CoA_binding_3 PF13727.1 EKE37463.1 - 0.054 13.3 0.0 0.054 13.3 0.0 2.4 2 0 0 2 2 2 0 CoA-binding domain Abhydrolase_5 PF12695.2 EKE37463.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PH PF00169.24 EKE37464.1 - 0.0078 16.4 0.8 0.018 15.2 0.5 1.6 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.12 EKE37465.1 - 4.2e-54 183.3 0.0 6.1e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37465.1 - 1.6e-53 181.5 0.0 2.8e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EKE37465.1 - 0.041 12.9 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EB PF01683.13 EKE37465.1 - 0.091 12.8 1.8 0.2 11.7 1.3 1.5 1 0 0 1 1 1 0 EB module VHS PF00790.14 EKE37466.1 - 5.3e-07 29.3 0.9 2.1e-06 27.4 0.0 2.4 3 1 0 3 3 3 1 VHS domain Cyclin_C PF02984.14 EKE37466.1 - 0.045 13.6 0.8 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain Vps53_N PF04100.7 EKE37467.1 - 2.4e-41 141.7 18.7 9.5e-38 129.9 5.3 2.7 3 0 0 3 3 3 2 Vps53-like, N-terminal DUF2451 PF10474.4 EKE37467.1 - 0.0016 18.2 0.5 0.0016 18.2 0.3 3.5 4 0 0 4 4 4 1 Protein of unknown function C-terminus (DUF2451) DUF3407 PF11887.3 EKE37467.1 - 0.007 15.6 0.1 0.018 14.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3407) CBFD_NFYB_HMF PF00808.18 EKE37467.1 - 0.056 13.4 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vps51 PF08700.6 EKE37467.1 - 2 8.2 8.5 0.094 12.5 0.5 2.9 3 0 0 3 3 3 0 Vps51/Vps67 RNase_PH PF01138.16 EKE37468.1 - 2.1e-21 76.6 0.0 3.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EKE37468.1 - 1.2e-07 31.5 0.1 2.9e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Rotamase PF00639.16 EKE37469.1 - 9.5e-20 71.1 0.1 1.2e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EKE37469.1 - 1.1e-14 54.7 0.0 1.3e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EKE37469.1 - 3.2e-05 24.5 0.0 4.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain TLD PF07534.11 EKE37470.1 - 0.004 17.1 0.7 0.01 15.8 0.5 1.7 1 0 0 1 1 1 1 TLD HTH_AraC PF00165.18 EKE37470.1 - 0.035 13.9 0.6 0.82 9.5 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Myotub-related PF06602.9 EKE37471.1 - 8.2e-78 261.6 1.1 1.2e-77 261.1 0.3 1.5 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain RhoGEF PF00621.15 EKE37473.1 - 2.1e-07 31.0 14.2 2.1e-07 31.0 9.8 2.3 2 0 0 2 2 2 1 RhoGEF domain LSM PF01423.17 EKE37474.1 - 5e-16 57.9 1.8 6.2e-16 57.6 1.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKE37474.1 - 0.0034 17.2 0.1 0.0045 16.8 0.1 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain SecY PF00344.15 EKE37474.1 - 0.022 13.6 0.1 0.025 13.5 0.1 1.1 1 0 0 1 1 1 0 SecY translocase DUF1521 PF07481.6 EKE37474.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) Got1 PF04178.7 EKE37475.1 - 1.8e-23 82.9 17.9 2.5e-23 82.4 12.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF846 PF05832.7 EKE37475.1 - 5.2 6.7 13.0 0.46 10.1 1.9 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) DUF423 PF04241.10 EKE37475.1 - 7 6.6 6.8 0.76 9.7 1.0 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF423) Myb_DNA-binding PF00249.26 EKE37476.1 - 2.6e-05 24.2 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1647 PF07801.6 EKE37476.1 - 0.064 12.7 1.0 0.98 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) PARP PF00644.15 EKE37478.1 - 2.4e-16 59.8 1.0 3.8e-14 52.6 0.7 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-CCHH PF10283.4 EKE37478.1 - 3.2e-06 26.8 3.1 3.7e-06 26.6 0.9 2.0 2 0 0 2 2 2 1 Zinc-finger (CX5CX6HX5H) motif Ribosomal_S27e PF01667.12 EKE37479.1 - 0.2 11.2 2.0 0.34 10.4 0.6 1.9 2 0 0 2 2 2 0 Ribosomal protein S27 DUF3353 PF11833.3 EKE37479.1 - 1.8 7.9 3.8 4.4 6.7 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) RGS PF00615.14 EKE37480.1 - 4.2e-14 52.6 5.3 4.2e-14 52.6 3.7 3.9 3 1 0 3 3 3 2 Regulator of G protein signaling domain SWIM PF04434.12 EKE37481.1 - 1.5e-07 30.7 0.8 1.5e-07 30.7 0.5 2.2 2 0 0 2 2 2 1 SWIM zinc finger DBD_Tnp_Mut PF03108.10 EKE37481.1 - 0.0033 16.9 0.2 0.0086 15.6 0.0 1.8 2 0 0 2 2 2 1 MuDR family transposase MULE PF10551.4 EKE37481.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 MULE transposase domain ADIP PF11559.3 EKE37481.1 - 0.093 12.6 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IPPT PF01715.12 EKE37482.1 - 2.7e-50 170.7 2.3 4.3e-50 170.0 1.6 1.3 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 EKE37482.1 - 1.3e-08 35.6 2.0 2.8e-07 31.3 1.4 3.0 1 1 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.3 EKE37482.1 - 5.8e-08 32.6 0.3 1.6e-07 31.2 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.1 EKE37482.1 - 1.8e-07 31.1 0.0 7.7e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain IPT PF01745.11 EKE37482.1 - 5.3e-07 29.0 0.4 2.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.2 EKE37482.1 - 7e-07 29.2 0.1 1.6e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SKI PF01202.17 EKE37482.1 - 2.6e-05 24.1 1.6 1.8 8.3 0.0 3.5 4 0 0 4 4 3 2 Shikimate kinase PRK PF00485.13 EKE37482.1 - 0.00017 21.1 0.7 0.0032 17.0 0.0 2.8 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EKE37482.1 - 0.00038 20.5 0.1 0.0055 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EKE37482.1 - 0.00075 18.7 1.4 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EKE37482.1 - 0.0027 16.8 0.0 0.0069 15.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin T2SE PF00437.15 EKE37482.1 - 0.0034 16.3 0.2 0.01 14.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 EKE37482.1 - 0.0039 17.4 1.1 0.0039 17.4 0.7 3.1 2 2 0 2 2 2 1 AAA domain RNA_pol_Rpb1_3 PF04983.13 EKE37482.1 - 0.007 16.1 0.7 0.016 14.9 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 Caudo_TAP PF02413.12 EKE37482.1 - 0.0079 16.3 3.4 0.021 14.9 2.0 2.1 1 1 0 1 1 1 1 Caudovirales tail fibre assembly protein RNA_helicase PF00910.17 EKE37482.1 - 0.013 15.6 0.2 0.087 12.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EKE37482.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EKE37482.1 - 0.027 14.4 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EKE37482.1 - 0.032 14.4 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EKE37482.1 - 0.035 13.8 0.1 0.09 12.4 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CoaE PF01121.15 EKE37482.1 - 0.066 12.6 1.0 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase zf-U1 PF06220.7 EKE37482.1 - 0.072 12.6 0.6 0.16 11.5 0.4 1.6 1 0 0 1 1 1 0 U1 zinc finger MMR_HSR1 PF01926.18 EKE37482.1 - 0.11 12.4 2.1 0.24 11.3 0.0 2.6 2 2 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EKE37482.1 - 0.11 12.0 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain Miro PF08477.8 EKE37482.1 - 0.87 10.1 5.2 0.55 10.7 0.1 3.0 3 2 0 3 3 3 0 Miro-like protein ABC_tran PF00005.22 EKE37482.1 - 2.1 8.6 8.0 14 5.9 5.5 2.5 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 EKE37482.1 - 2.1 8.1 6.3 0.58 9.9 0.1 2.7 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 EKE37484.1 - 3.2e-50 170.1 0.5 6.2e-50 169.2 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EKE37484.1 - 1.1e-16 60.4 0.0 2.9e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EKE37484.1 - 7.2e-09 35.3 0.0 1.9e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EKE37484.1 - 9.5e-08 31.6 0.0 4.5e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EKE37484.1 - 2e-05 24.5 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EKE37484.1 - 0.015 15.7 0.1 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein START PF01852.14 EKE37487.1 - 7.2e-23 80.9 0.3 9.9e-23 80.5 0.2 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE37487.1 - 0.001 18.7 3.0 0.0044 16.6 2.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) YtzH PF14165.1 EKE37489.1 - 0.15 12.2 0.7 0.26 11.5 0.1 1.7 2 0 0 2 2 2 0 YtzH-like protein DUF1725 PF08333.6 EKE37489.1 - 1.9 7.9 6.4 0.25 10.7 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Alpha_E3_glycop PF01563.11 EKE37490.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein TLD PF07534.11 EKE37492.1 - 1.8e-06 28.0 4.8 2.2e-06 27.6 3.3 1.1 1 0 0 1 1 1 1 TLD Peptidase_C48 PF02902.14 EKE37493.1 - 1.2e-07 31.5 2.9 1e-06 28.5 2.0 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SNF2_N PF00176.18 EKE37494.1 - 5.8e-63 212.4 0.1 5.8e-63 212.4 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE37494.1 - 2.2e-12 46.6 0.0 4.8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE37494.1 - 2.1e-09 37.0 0.0 1.1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EKE37494.1 - 0.025 13.3 0.0 0.078 11.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 AAA_22 PF13401.1 EKE37494.1 - 0.051 13.7 0.0 27 4.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain N2227 PF07942.7 EKE37495.1 - 7.6e-43 146.4 0.7 1.1e-42 145.9 0.5 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_31 PF13847.1 EKE37495.1 - 0.00016 21.2 3.4 0.014 15.0 0.1 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EKE37495.1 - 0.012 16.0 0.0 0.18 12.3 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EKE37495.1 - 0.021 15.2 0.0 0.06 13.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L37ae PF01780.14 EKE37496.1 - 5.2e-38 128.8 9.1 5.9e-38 128.6 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EKE37496.1 - 0.0051 16.2 5.2 0.33 10.4 0.3 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EKE37496.1 - 0.0054 16.5 8.0 0.0077 16.0 5.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 EKE37496.1 - 0.15 12.4 3.2 1.8 8.9 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Sgf11 PF08209.6 EKE37496.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.5 EKE37496.1 - 0.57 10.1 5.7 1.8 8.5 0.8 2.5 2 1 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 EKE37496.1 - 5.7 6.7 8.3 0.76 9.5 0.9 2.2 1 1 1 2 2 2 0 BED zinc finger Arrestin_N PF00339.24 EKE37498.1 - 3.3e-15 56.2 0.1 9.5e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain WW PF00397.21 EKE37498.1 - 1.8e-11 43.6 2.6 5.2e-08 32.5 1.4 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.25 EKE37498.1 - 1e-06 28.4 0.1 2.4e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain LDB19 PF13002.2 EKE37498.1 - 0.0091 15.5 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_C PF02752.17 EKE37498.1 - 0.3 11.1 4.5 0.15 12.2 0.3 2.4 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain TLD PF07534.11 EKE37500.1 - 4.9e-07 29.8 0.3 8e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 TLD FAM195 PF14799.1 EKE37500.1 - 0.041 13.7 3.2 0.031 14.1 1.2 1.6 2 0 0 2 2 2 0 FAM195 family PWI PF01480.12 EKE37500.1 - 4.5 7.4 9.0 0.91 9.6 0.5 3.0 3 1 1 4 4 4 0 PWI domain HTH_32 PF13565.1 EKE37501.1 - 1.9e-07 31.7 0.0 1.2e-05 25.9 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EKE37501.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EKE37501.1 - 2.2e-06 27.5 0.1 4.5e-05 23.3 0.0 2.7 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EKE37501.1 - 2.5e-06 26.9 0.1 2.1e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 EKE37501.1 - 4e-06 26.2 0.0 8.2e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.1 EKE37501.1 - 3.2e-05 23.6 0.0 8.7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.8 EKE37501.1 - 0.00039 19.7 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Linker_histone PF00538.14 EKE37501.1 - 0.0024 17.9 0.6 0.48 10.5 0.0 3.1 3 0 0 3 3 3 1 linker histone H1 and H5 family HTH_Tnp_1 PF01527.15 EKE37501.1 - 0.0082 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Transposase KorB PF08535.5 EKE37501.1 - 0.019 15.1 0.0 0.075 13.1 0.0 1.9 1 1 1 2 2 2 0 KorB domain HTH_11 PF08279.7 EKE37501.1 - 0.031 13.9 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 HTH domain GerE PF00196.14 EKE37501.1 - 0.034 13.4 0.1 0.24 10.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Frigida PF07899.6 EKE37501.1 - 0.053 12.2 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Frigida-like protein HTH_40 PF14493.1 EKE37501.1 - 0.08 13.1 0.2 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EKE37501.1 - 0.085 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 ACDC PF14733.1 EKE37501.1 - 0.1 12.7 0.8 0.25 11.4 0.5 1.6 1 0 0 1 1 1 0 AP2-coincident C-terminal HTH_Tnp_Tc3_2 PF01498.13 EKE37501.1 - 0.12 12.4 0.2 11 6.2 0.0 2.4 1 1 1 2 2 2 0 Transposase HU-DNA_bdg PF14848.1 EKE37501.1 - 0.13 11.9 0.1 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 DNA-binding domain PTCB-BRCT PF12738.2 EKE37502.1 - 2.5e-18 65.6 0.0 3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKE37502.1 - 2.9e-11 43.3 0.0 3.5e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Spore_YhaL PF14147.1 EKE37502.1 - 0.084 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL PTCB-BRCT PF12738.2 EKE37503.1 - 1.8e-13 50.0 0.0 2.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKE37503.1 - 6.5e-12 45.4 0.0 8.8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.17 EKE37504.1 - 6.9e-14 51.2 0.1 1.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37504.1 - 1.9e-12 46.9 0.1 2.9e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE37504.1 - 5.1e-11 42.2 0.1 8.3e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GH-E PF14410.1 EKE37504.1 - 0.016 15.3 0.3 0.038 14.1 0.2 1.6 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Hist_deacetyl PF00850.14 EKE37504.1 - 0.084 12.1 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain HAD_2 PF13419.1 EKE37505.1 - 1.7e-16 60.9 0.0 2.1e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EKE37505.1 - 0.00021 20.9 3.1 0.00042 20.0 1.4 1.9 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.1 EKE37505.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EKE37505.1 - 0.0025 17.9 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE37505.1 - 0.011 16.2 0.0 0.2 12.0 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase UPF0302 PF08864.5 EKE37505.1 - 0.042 13.6 1.3 0.071 12.9 0.3 1.9 2 0 0 2 2 2 0 UPF0302 domain DNA_primase_S PF01896.14 EKE37505.1 - 0.089 12.6 0.4 0.16 11.7 0.3 1.5 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit GIY-YIG PF01541.19 EKE37506.1 - 5.6e-08 33.0 0.3 4.8e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 GIY-YIG catalytic domain DiS_P_DiS PF06750.8 EKE37506.1 - 0.0016 18.1 4.8 0.21 11.4 0.5 3.0 3 0 0 3 3 3 2 Bacterial Peptidase A24 N-terminal domain OrfB_Zn_ribbon PF07282.6 EKE37506.1 - 0.013 15.1 3.0 0.02 14.5 0.4 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Cas_Cas6 PF01881.11 EKE37506.1 - 0.021 15.0 0.9 0.04 14.1 0.6 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas6 zf-RING_2 PF13639.1 EKE37506.1 - 0.033 14.0 10.4 0.095 12.5 7.2 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EKE37506.1 - 0.06 13.0 9.7 0.15 11.7 6.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EKE37506.1 - 0.13 12.0 8.2 0.29 10.8 2.7 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EKE37506.1 - 0.3 11.0 7.6 1.2 9.1 5.3 2.1 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EKE37506.1 - 0.79 9.3 8.9 1.9 8.1 6.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Metallophos PF00149.23 EKE37507.1 - 2e-30 105.6 1.6 3.1e-30 105.0 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EKE37507.1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region DUF655 PF04919.7 EKE37508.1 - 0.0084 15.8 0.5 0.011 15.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF655) Glyco_hydro_66 PF13199.1 EKE37508.1 - 0.059 11.7 0.6 0.068 11.5 0.4 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 SRI PF08236.6 EKE37508.1 - 0.95 9.4 7.4 2 8.4 2.5 2.3 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Pkinase_Tyr PF07714.12 EKE37509.1 - 1.5e-16 60.2 0.0 1.9e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37509.1 - 1.4e-10 40.7 0.0 2.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EKE37510.1 - 1.8e-28 99.3 0.1 3.2e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37510.1 - 2.1e-28 99.1 0.1 3.5e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.8 EKE37510.1 - 1.3e-06 27.3 39.4 1.3e-06 27.3 27.3 6.6 1 1 5 6 6 6 4 Giardia variant-specific surface protein TMEM154 PF15102.1 EKE37510.1 - 0.0057 16.3 3.3 0.013 15.2 2.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family Motile_Sperm PF00635.21 EKE37510.1 - 0.014 15.0 0.2 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 MSP (Major sperm protein) domain ODV-E18 PF10717.4 EKE37510.1 - 0.025 13.9 1.4 0.053 12.9 1.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 TMEM89 PF15098.1 EKE37510.1 - 0.045 13.7 6.5 1.2 9.1 0.8 2.5 2 0 0 2 2 2 0 TMEM89 protein family DUF912 PF06024.7 EKE37510.1 - 0.074 13.1 0.5 0.19 11.7 0.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ASFV_J13L PF05568.6 EKE37510.1 - 1.8 8.0 5.3 3.6 7.0 3.7 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3827 PF12877.2 EKE37510.1 - 2.4 6.1 7.3 3.4 5.6 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Baculo_11_kDa PF06143.6 EKE37510.1 - 3.5 7.0 7.5 7.4 6.0 5.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1223 PF06764.6 EKE37511.1 - 0.35 10.6 4.8 0.7 9.6 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) RhoGAP PF00620.22 EKE37512.1 - 6.6e-20 71.2 0.5 1.9e-19 69.7 0.3 1.8 1 0 0 1 1 1 1 RhoGAP domain VOMI PF03762.12 EKE37513.1 - 0.028 14.3 0.4 0.031 14.2 0.3 1.0 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) DUF916 PF06030.7 EKE37513.1 - 0.097 12.4 0.9 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) RRM_1 PF00076.17 EKE37514.1 - 2.3e-37 126.4 12.5 2.6e-12 46.2 0.1 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37514.1 - 2.4e-36 123.5 0.8 7.8e-11 41.7 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE37514.1 - 1.7e-18 66.1 4.9 1.3e-06 28.1 0.1 5.0 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EKE37514.1 - 3.9e-07 29.6 0.6 7.8e-07 28.6 0.4 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EKE37514.1 - 0.0011 18.7 2.3 2 8.2 0.1 3.9 3 1 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF1987 PF09345.5 EKE37514.1 - 0.0017 18.1 0.8 0.049 13.4 0.2 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF1987) Thioredoxin_8 PF13905.1 EKE37514.1 - 0.026 14.6 9.7 0.67 10.1 0.0 4.5 3 2 1 4 4 4 0 Thioredoxin-like Ribosomal_S19e PF01090.14 EKE37515.1 - 1.4e-55 186.5 0.2 1.6e-55 186.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Pex19 PF04614.7 EKE37518.1 - 1.5e-22 80.4 4.1 1.8e-22 80.1 2.9 1.1 1 0 0 1 1 1 1 Pex19 protein family SHOCT PF09851.4 EKE37518.1 - 3.1 7.4 4.8 3.7 7.1 0.8 2.3 2 0 0 2 2 2 0 Short C-terminal domain RabGAP-TBC PF00566.13 EKE37519.1 - 1.6e-27 96.4 8.7 3.8e-27 95.1 6.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF1626 PF07788.6 EKE37519.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1626) DUF853 PF05872.7 EKE37519.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Ribosomal_L28e PF01778.12 EKE37520.1 - 1.6e-26 93.0 0.1 1.6e-26 93.0 0.0 1.9 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.9 EKE37520.1 - 3.4e-05 23.8 17.5 3.4e-05 23.8 12.1 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region DUF2009 PF09418.5 EKE37520.1 - 0.016 14.0 7.9 0.02 13.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Prominin PF05478.6 EKE37520.1 - 1.9 5.8 6.6 1.5 6.2 0.8 2.0 1 1 1 2 2 2 0 Prominin Exonuc_VII_L PF02601.10 EKE37520.1 - 3.3 6.7 12.5 7.1 5.7 8.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.3 EKE37520.1 - 4.7 7.2 16.0 0.13 12.2 4.1 2.2 1 1 1 2 2 2 0 YlqD protein Pex16 PF08610.5 EKE37521.1 - 0.02 13.9 5.8 0.023 13.7 4.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ycf1 PF05758.7 EKE37521.1 - 0.058 11.1 20.2 0.069 10.8 14.0 1.1 1 0 0 1 1 1 0 Ycf1 ATP-synt_S1 PF05827.7 EKE37521.1 - 0.24 10.6 6.9 0.32 10.2 4.8 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF1510 PF07423.6 EKE37521.1 - 0.5 9.7 31.0 0.17 11.2 19.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) BSMAP PF12280.3 EKE37521.1 - 0.73 9.6 6.5 1.2 8.9 4.5 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein CDC45 PF02724.9 EKE37521.1 - 0.73 7.8 16.2 0.81 7.6 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EKE37521.1 - 1.2 8.0 5.9 1.8 7.4 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 EKE37521.1 - 1.4 8.0 9.4 1.8 7.6 6.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 EKE37521.1 - 2.1 5.9 12.1 2.5 5.6 8.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 EKE37521.1 - 9.5 6.0 11.9 14 5.5 8.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Fer4 PF00037.22 EKE37522.1 - 1.9e-15 55.7 16.9 1.2e-09 37.3 3.6 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EKE37522.1 - 4.9e-11 42.0 14.0 4.9e-07 29.3 2.6 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EKE37522.1 - 6.5e-11 42.4 13.3 1.1e-10 41.7 9.3 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE37522.1 - 2.2e-10 40.1 11.2 3e-10 39.7 7.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE37522.1 - 3.6e-10 39.1 15.7 5.8e-07 29.0 2.6 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EKE37522.1 - 4.1e-10 39.7 11.6 5.8e-10 39.2 8.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.2 EKE37522.1 - 3.7e-09 36.1 15.8 1.1e-05 25.4 2.9 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EKE37522.1 - 7.4e-09 35.8 10.8 0.00015 22.0 1.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKE37522.1 - 3.7e-08 33.2 12.0 1.8e-07 31.1 8.3 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EKE37522.1 - 1.4e-07 32.1 10.7 0.0009 19.9 1.4 2.0 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EKE37522.1 - 3.8e-07 29.8 13.8 5.9e-07 29.2 9.5 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 EKE37522.1 - 3.2e-06 27.5 15.4 0.0032 18.0 2.0 2.1 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 EKE37522.1 - 3.3e-06 27.4 18.6 0.00011 22.5 3.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EKE37522.1 - 2.6e-05 24.5 18.9 0.0065 16.8 3.5 2.1 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EKE37522.1 - 4.1e-05 23.8 22.1 0.00024 21.4 5.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_11 PF13247.1 EKE37522.1 - 0.043 13.6 3.4 0.18 11.6 2.4 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain RseC_MucC PF04246.7 EKE37522.1 - 5.9 6.4 8.2 5.2 6.6 1.1 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF678 PF05077.7 EKE37522.1 - 7.2 6.6 9.4 11 6.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF678) Fer4 PF00037.22 EKE37523.1 - 1.6e-15 55.9 17.1 1e-09 37.5 3.7 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EKE37523.1 - 2.7e-11 42.8 13.9 2.7e-07 30.1 2.5 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EKE37523.1 - 3.4e-11 43.3 13.5 4.5e-11 42.9 9.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE37523.1 - 1.5e-10 40.6 11.4 2e-10 40.3 7.9 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKE37523.1 - 2.7e-10 40.3 11.6 3.6e-10 39.9 8.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE37523.1 - 7e-10 38.2 15.6 1.1e-06 28.1 2.5 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EKE37523.1 - 2.9e-09 36.5 15.8 8.2e-06 25.7 2.9 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EKE37523.1 - 7.6e-09 35.7 10.4 0.00017 21.8 0.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKE37523.1 - 2e-08 34.1 11.9 9.3e-08 31.9 8.2 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EKE37523.1 - 1e-07 32.5 10.1 0.00074 20.2 1.2 2.0 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EKE37523.1 - 1.2e-07 31.5 13.8 1.8e-07 30.9 9.6 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EKE37523.1 - 2.5e-06 27.8 18.9 8.4e-05 22.9 3.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EKE37523.1 - 3.3e-06 27.5 15.0 0.0032 18.0 2.0 2.1 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 EKE37523.1 - 2e-05 24.8 18.0 0.0065 16.8 3.5 2.1 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EKE37523.1 - 2.9e-05 24.3 22.2 0.00017 21.9 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_11 PF13247.1 EKE37523.1 - 0.11 12.4 4.2 0.36 10.7 2.9 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain RseC_MucC PF04246.7 EKE37523.1 - 8.7 5.9 7.7 3.5 7.2 1.0 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF678 PF05077.7 EKE37523.1 - 8.7 6.4 9.7 11 6.0 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF678) SieB PF14163.1 EKE37524.1 - 0.043 13.3 3.3 0.15 11.6 2.3 2.1 1 1 0 1 1 1 0 Superinfection exclusion protein B Cyclin_N PF00134.18 EKE37525.1 - 9e-14 51.1 1.5 1.8e-13 50.1 1.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Abhydrolase_5 PF12695.2 EKE37526.1 - 5.2e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EKE37526.1 - 0.00013 20.5 0.3 0.00027 19.5 0.2 1.5 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.8 EKE37526.1 - 0.0094 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKE37526.1 - 0.15 11.4 1.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase YchF-GTPase_C PF06071.8 EKE37527.1 - 2.7e-38 129.6 0.5 6.2e-38 128.4 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EKE37527.1 - 6.8e-18 64.7 0.0 2.4e-17 62.9 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE37527.1 - 1.7e-08 33.8 0.0 4.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 EKE37527.1 - 0.0035 17.0 0.0 0.85 9.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EKE37527.1 - 0.0046 15.7 0.0 0.0078 15.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_14 PF13173.1 EKE37527.1 - 0.023 14.5 0.2 0.25 11.2 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EKE37527.1 - 0.034 14.9 0.0 0.14 12.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain Arteri_GP4 PF02497.10 EKE37527.1 - 0.037 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus glycoprotein GTP_EFTU PF00009.22 EKE37527.1 - 0.041 13.3 0.2 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EKE37527.1 - 0.047 13.0 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EKE37527.1 - 0.071 12.3 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family RNA_helicase PF00910.17 EKE37527.1 - 0.094 12.9 0.0 26 5.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 EKE37527.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain GAGA_bind PF06217.7 EKE37528.1 - 0.052 13.5 5.7 0.057 13.3 3.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3546 PF12066.3 EKE37528.1 - 0.36 10.8 9.9 2.3 8.2 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3546) PsiA PF06952.6 EKE37528.1 - 0.45 9.5 4.5 0.57 9.1 3.1 1.1 1 0 0 1 1 1 0 PsiA protein Erythro_esteras PF05139.9 EKE37528.1 - 0.58 9.2 3.9 0.65 9.1 2.7 1.1 1 0 0 1 1 1 0 Erythromycin esterase DUF2353 PF09789.4 EKE37528.1 - 1.3 8.2 16.5 1.6 7.8 11.4 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) IPK PF03770.11 EKE37528.1 - 3.2 7.3 10.0 5.4 6.5 7.0 1.3 1 1 0 1 1 1 0 Inositol polyphosphate kinase FKBP_N PF01346.13 EKE37528.1 - 4 7.4 14.0 1.9 8.5 8.0 1.7 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Chordopox_G3 PF06129.7 EKE37528.1 - 6.6 6.9 6.5 2.7 8.1 0.2 2.1 1 1 1 2 2 2 0 Chordopoxvirus G3 protein M60-like PF13402.1 EKE37530.1 - 1.6e-29 102.7 3.6 9e-29 100.3 0.7 2.4 2 0 0 2 2 2 2 Peptidase M60-like family PqiA PF04403.8 EKE37531.1 - 2.5e-14 53.1 32.2 1.6e-09 37.5 4.3 3.2 4 0 0 4 4 4 2 Paraquat-inducible protein A Peptidase_S49_N PF08496.5 EKE37531.1 - 0.01 15.6 0.7 0.049 13.4 0.5 2.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EphA2_TM PF14575.1 EKE37531.1 - 0.53 10.7 6.8 3.7 7.9 0.0 4.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF1394 PF07159.7 EKE37532.1 - 3.8e-74 249.5 0.1 4.4e-74 249.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) AAA_18 PF13238.1 EKE37533.1 - 8.1e-06 26.1 0.8 0.00017 21.9 0.6 2.4 1 1 0 1 1 1 1 AAA domain dNK PF01712.14 EKE37533.1 - 2.7e-05 24.0 1.2 0.015 15.1 0.1 2.6 1 1 1 2 2 2 2 Deoxynucleoside kinase TrwB_AAD_bind PF10412.4 EKE37533.1 - 0.00047 18.9 0.0 0.00078 18.1 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 EKE37533.1 - 0.0007 20.4 0.3 0.0023 18.7 0.1 2.0 1 1 1 2 2 2 1 AAA domain cobW PF02492.14 EKE37533.1 - 0.0034 16.8 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EKE37533.1 - 0.0045 16.0 0.0 0.012 14.6 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 EKE37533.1 - 0.0085 15.5 0.4 0.016 14.7 0.3 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 EKE37533.1 - 0.0085 15.8 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EKE37533.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 EKE37533.1 - 0.015 14.1 0.0 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.12 EKE37533.1 - 0.023 14.0 0.9 3 7.1 0.0 2.5 2 1 0 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.10 EKE37533.1 - 0.041 13.5 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 EKE37533.1 - 0.042 13.8 0.1 1.2 9.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EKE37533.1 - 0.05 12.7 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Tymo_coat PF00983.13 EKE37533.1 - 0.056 13.1 0.1 0.088 12.5 0.1 1.2 1 0 0 1 1 1 0 Tymovirus coat protein AAA PF00004.24 EKE37533.1 - 0.089 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKE37533.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EKE37533.1 - 0.13 12.7 0.7 3 8.3 0.1 2.7 2 2 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EKE37533.1 - 4 7.7 8.8 15 5.8 6.1 2.1 1 1 0 1 1 1 0 AAA domain Med18 PF09637.5 EKE37536.1 - 0.012 15.2 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 0 Med18 protein Elongin_A PF06881.6 EKE37536.1 - 9.4 6.6 10.8 4.7 7.6 4.5 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TniB PF05621.6 EKE37537.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DUF2570 PF10828.3 EKE37537.1 - 7.1 6.2 7.8 32 4.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Mucin PF01456.12 EKE37538.1 - 0.005 16.6 15.4 0.005 16.6 10.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Podoplanin PF05808.6 EKE37538.1 - 0.16 11.5 7.1 0.22 11.0 4.9 1.2 1 0 0 1 1 1 0 Podoplanin SSP160 PF06933.6 EKE37538.1 - 0.28 9.1 12.9 0.3 9.0 9.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EKE37538.1 - 0.42 8.3 9.4 0.45 8.2 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SUR7 PF06687.7 EKE37538.1 - 0.5 9.8 6.0 0.92 9.0 4.1 1.5 1 1 0 1 1 1 0 SUR7/PalI family CAML PF14963.1 EKE37538.1 - 0.59 9.4 4.2 0.72 9.1 2.9 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Presenilin PF01080.12 EKE37538.1 - 0.95 8.2 3.7 1 8.0 2.6 1.2 1 0 0 1 1 1 0 Presenilin Glycophorin_A PF01102.13 EKE37538.1 - 2.8 7.7 7.8 5.9 6.6 5.4 1.6 1 1 0 1 1 1 0 Glycophorin A TMEM154 PF15102.1 EKE37538.1 - 6 6.5 13.1 2.1 8.0 6.3 2.0 1 1 1 2 2 2 0 TMEM154 protein family HSP70 PF00012.15 EKE37539.1 - 7.1e-16 57.2 10.6 8e-16 57.0 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein RAMPs PF03787.10 EKE37539.1 - 0.031 14.1 0.2 0.036 13.8 0.2 1.1 1 0 0 1 1 1 0 RAMP superfamily tRNA_anti-like PF12869.2 EKE37539.1 - 0.062 12.7 2.5 0.11 12.0 1.8 1.5 1 1 0 1 1 1 0 tRNA_anti-like SBP_bac_7 PF03480.8 EKE37539.1 - 0.087 11.9 3.3 0.078 12.0 1.6 1.4 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Pex19 PF04614.7 EKE37539.1 - 0.14 11.7 6.5 0.4 10.2 4.5 1.6 1 1 0 1 1 1 0 Pex19 protein family GrpE PF01025.14 EKE37539.1 - 0.19 11.2 7.9 0.31 10.5 5.5 1.3 1 0 0 1 1 1 0 GrpE PhaP_Bmeg PF09602.5 EKE37539.1 - 0.48 10.2 6.3 0.45 10.3 0.7 2.0 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) KMP11 PF03037.11 EKE37539.1 - 0.49 11.0 7.1 5 7.7 4.9 2.0 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF1366 PF07104.6 EKE37539.1 - 0.58 9.7 9.1 0.24 11.0 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) DUF3510 PF12022.3 EKE37539.1 - 0.59 10.2 3.9 4.3 7.4 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) DUF4446 PF14584.1 EKE37539.1 - 1 9.1 7.1 0.98 9.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) CENP-N PF05238.8 EKE37539.1 - 1.2 8.1 4.5 1.4 7.8 3.1 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4473 PF14747.1 EKE37539.1 - 7.5 6.8 11.6 1.8 8.8 5.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4473) Tho2 PF11262.3 EKE37540.1 - 5.8e-11 41.9 12.0 5.8e-11 41.9 8.3 2.4 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EKE37540.1 - 0.011 15.5 0.1 0.05 13.3 0.0 2.3 2 0 0 2 2 2 0 Transcription- and export-related complex subunit RhoGAP PF00620.22 EKE37541.1 - 6.6e-34 116.7 0.0 1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SNARE PF05739.14 EKE37542.1 - 1.3e-09 37.6 0.5 3.3e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EKE37542.1 - 0.0038 17.3 6.3 0.0085 16.2 4.3 1.8 1 1 0 1 1 1 1 Syntaxin Vhr1 PF04001.8 EKE37542.1 - 0.066 13.1 3.0 0.11 12.4 1.3 1.8 1 1 1 2 2 2 0 Transcription factor Vhr1 RNA_pol_Rpb5_C PF01191.14 EKE37542.1 - 0.13 11.9 4.0 0.13 11.8 1.2 2.1 1 1 1 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DUF2209 PF09974.4 EKE37542.1 - 0.14 12.2 0.3 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) NTP_transferase PF00483.18 EKE37544.1 - 4e-47 160.6 0.0 7e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EKE37544.1 - 2.2e-05 24.5 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 EKE37544.1 - 0.00074 19.1 0.0 0.044 13.3 0.0 2.4 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Pkinase PF00069.20 EKE37545.1 - 1.8e-64 217.3 0.1 1.8e-64 217.3 0.1 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37545.1 - 2.5e-47 161.1 0.0 4.6e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37545.1 - 0.00015 20.8 0.0 0.00032 19.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKE37545.1 - 0.0067 15.5 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FlaC_arch PF05377.6 EKE37545.1 - 0.83 9.5 11.5 0.075 12.9 0.4 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ORF6C PF10552.4 EKE37545.1 - 3.2 7.4 11.8 0.4 10.4 2.1 3.7 3 0 0 3 3 3 0 ORF6C domain DEAD PF00270.24 EKE37546.1 - 2.1e-25 89.1 0.5 2.5e-24 85.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE37546.1 - 7e-22 77.0 0.1 1.6e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE37546.1 - 0.00025 20.9 0.0 0.00025 20.9 0.0 2.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Zea_mays_MuDR PF05928.6 EKE37546.1 - 0.042 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Aa_trans PF01490.13 EKE37547.1 - 2.2e-17 62.6 39.3 5e-17 61.4 27.2 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EKE37547.1 - 0.014 14.2 39.2 0.0059 15.4 23.7 2.5 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family KASH PF10541.4 EKE37547.1 - 0.83 9.5 0.0 0.83 9.5 0.0 2.8 3 0 0 3 3 3 0 Nuclear envelope localisation domain DUF2205 PF10224.4 EKE37548.1 - 4.7e-07 29.2 3.5 1.2e-06 27.9 2.5 1.7 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EKE37548.1 - 0.013 15.7 4.9 0.013 15.7 3.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EKE37548.1 - 0.026 14.4 4.2 0.026 14.4 2.9 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Glyco_hydro_57 PF03065.10 EKE37548.1 - 0.032 13.1 0.3 0.057 12.3 0.2 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 TBCA PF02970.11 EKE37548.1 - 0.068 13.2 2.1 7.2 6.7 0.7 2.5 2 0 0 2 2 2 0 Tubulin binding cofactor A FIVAR PF07554.8 EKE37548.1 - 0.07 13.3 1.9 2 8.7 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain bZIP_1 PF00170.16 EKE37548.1 - 0.071 13.0 3.2 0.18 11.8 2.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIVA PF05103.8 EKE37548.1 - 0.13 12.3 3.7 0.24 11.4 1.7 1.9 2 0 0 2 2 2 0 DivIVA protein GCOM2 PF15328.1 EKE37548.1 - 0.14 11.9 2.2 0.18 11.5 1.5 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 bZIP_2 PF07716.10 EKE37548.1 - 0.37 10.6 4.8 0.88 9.4 3.3 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Chibby PF14645.1 EKE37548.1 - 2.6 7.9 10.6 9.2 6.1 2.3 2.2 1 1 1 2 2 2 0 Chibby family RIH_assoc PF08454.6 EKE37548.1 - 4.4 6.9 10.6 33 4.1 1.9 3.6 1 1 2 3 3 3 0 RyR and IP3R Homology associated HSP70 PF00012.15 EKE37549.1 - 2.5e-07 29.0 0.5 2.5e-07 29.0 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein PolyA_pol PF01743.15 EKE37550.1 - 1.1e-30 106.3 1.1 1.8e-30 105.7 0.4 1.6 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EKE37550.1 - 0.00022 20.7 0.0 0.00081 18.9 0.0 2.1 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EKE37550.1 - 0.00034 20.4 4.2 0.0013 18.5 1.9 2.4 2 1 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative SH3_1 PF00018.23 EKE37551.1 - 1.7e-14 52.9 0.1 6.1e-14 51.1 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EKE37551.1 - 2.5e-11 42.9 0.0 5.4e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE37551.1 - 6e-10 38.4 0.0 3.6e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Cofilin_ADF PF00241.15 EKE37551.1 - 5e-07 29.6 0.2 1.3e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PAT1 PF09770.4 EKE37551.1 - 1.1 7.4 60.4 1.4 7.0 41.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNB PF00773.14 EKE37552.1 - 8.8e-06 25.2 0.2 8.8e-06 25.2 0.1 1.8 2 1 0 2 2 2 1 RNB domain Orthopox_B11R PF07033.6 EKE37552.1 - 0.21 11.0 6.6 0.26 10.7 0.7 2.8 1 1 1 2 2 2 0 Orthopoxvirus B11R protein Pkinase PF00069.20 EKE37553.1 - 1.8e-73 246.9 0.0 2.1e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37553.1 - 1.2e-35 122.8 0.1 4.6e-35 120.9 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37553.1 - 4.1e-08 32.5 0.1 8e-07 28.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EKE37553.1 - 0.011 15.4 0.1 0.15 11.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HTH_WhiA PF02650.9 EKE37554.1 - 0.0082 16.5 0.7 0.012 16.0 0.5 1.2 1 0 0 1 1 1 1 WhiA C-terminal HTH domain SR-25 PF10500.4 EKE37554.1 - 0.027 13.9 0.0 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PH_6 PF15406.1 EKE37556.1 - 0.037 14.0 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Sec3_C PF09763.4 EKE37557.1 - 2e-39 135.3 31.0 1.6e-20 72.9 13.4 2.4 1 1 1 2 2 2 2 Exocyst complex component Sec3 Choline_kinase PF01633.15 EKE37558.1 - 1.8e-51 174.7 1.0 2.7e-51 174.1 0.7 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKE37558.1 - 2.2e-12 47.2 0.0 3.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKE37558.1 - 1.3e-05 24.4 0.5 2.4e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EKE37558.1 - 0.018 13.7 0.2 0.024 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.9 EKE37558.1 - 0.075 12.0 0.1 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM PF01423.17 EKE37559.1 - 0.00013 21.3 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 EKE37559.1 - 0.0024 17.5 0.1 0.0035 17.0 0.1 1.3 1 1 0 1 1 1 1 Biotin protein ligase C terminal domain VIT1 PF01988.14 EKE37560.1 - 1.9 7.9 3.0 3.5 7.0 2.1 1.4 1 0 0 1 1 1 0 VIT family Glyco_hydro_77 PF02446.12 EKE37561.1 - 1.4e-131 439.4 0.1 1.9e-131 439.0 0.1 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.14 EKE37561.1 - 4.5e-16 58.2 0.0 2.3e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 Starch binding domain Pkinase_Tyr PF07714.12 EKE37562.1 - 3.3e-49 167.2 0.0 5.2e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37562.1 - 9.4e-42 142.9 0.0 1.9e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SEP PF08059.8 EKE37563.1 - 2.3e-17 63.0 0.3 1.5e-16 60.4 0.0 2.4 3 0 0 3 3 3 1 SEP domain UBX PF00789.15 EKE37563.1 - 8.1e-06 25.8 0.1 1.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 UBX domain LRR_5 PF13306.1 EKE37564.1 - 8.9e-62 206.5 30.3 1.3e-20 73.4 2.6 4.1 3 1 1 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37564.1 - 4.1e-21 74.4 7.5 2.7e-05 23.8 0.0 6.7 4 3 5 9 9 9 8 Leucine rich repeat Mob1_phocein PF03637.12 EKE37565.1 - 9.7e-52 175.1 0.3 1.2e-51 174.8 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF3717 PF12512.3 EKE37565.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) RasGEF PF00617.14 EKE37567.1 - 2e-48 164.6 0.2 1.1e-47 162.1 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE37567.1 - 3.3e-13 49.6 2.3 6.4e-13 48.7 0.1 2.5 2 1 1 3 3 3 1 RasGEF N-terminal motif DUF4404 PF14357.1 EKE37567.1 - 0.15 12.4 2.6 0.64 10.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) SET PF00856.23 EKE37568.1 - 0.00016 22.0 3.3 0.0042 17.4 0.1 3.6 2 2 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 EKE37568.1 - 0.0093 15.8 0.7 0.031 14.1 0.3 1.9 1 1 1 2 2 2 1 Rubisco LSMT substrate-binding WD40 PF00400.27 EKE37569.1 - 1.9e-10 40.2 0.9 0.00037 20.2 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE37569.1 - 0.03 14.1 0.0 0.13 12.0 0.0 2.2 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1513 PF07433.6 EKE37569.1 - 0.17 10.7 0.0 0.4 9.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) AsnA PF03590.10 EKE37570.1 - 3.6e-86 288.5 0.5 4.7e-86 288.2 0.4 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.15 EKE37570.1 - 4.2e-05 22.4 0.9 0.0069 15.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) LRR_5 PF13306.1 EKE37571.1 - 1.4e-57 192.9 27.6 6e-29 100.3 7.7 2.9 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37571.1 - 4.6e-23 80.7 7.7 1.7e-07 30.8 0.2 4.8 2 2 3 5 5 5 5 Leucine rich repeat FNIP PF05725.7 EKE37571.1 - 0.65 9.9 0.1 0.65 9.9 0.0 5.2 5 1 0 5 5 5 0 FNIP Repeat FNIP PF05725.7 EKE37572.1 - 6.8 6.7 7.7 3.4 7.6 0.2 3.7 4 1 0 4 4 4 0 FNIP Repeat CTNNBL PF08216.6 EKE37573.1 - 0.079 12.5 0.5 0.084 12.4 0.3 1.1 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Pkinase PF00069.20 EKE37574.1 - 5.9e-62 209.1 0.0 9.2e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37574.1 - 5.9e-45 153.3 0.0 1.1e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37574.1 - 6e-06 25.4 0.0 1.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKE37574.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 EKE37574.1 - 0.042 13.8 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.17 EKE37574.1 - 0.048 13.0 0.1 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EKE37574.1 - 0.16 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PNK3P PF08645.6 EKE37575.1 - 5.7e-56 188.3 0.9 1.2e-55 187.2 0.6 1.6 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EKE37575.1 - 1.6e-17 63.7 0.0 1.9e-16 60.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKE37575.1 - 0.039 14.0 0.1 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EKE37575.1 - 0.046 14.5 0.0 0.15 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKE37575.1 - 0.053 12.5 0.0 0.15 11.1 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 EKE37575.1 - 0.08 12.1 1.3 7.3 5.7 0.9 2.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Hydrolase_3 PF08282.7 EKE37575.1 - 0.36 10.3 4.2 0.61 9.6 0.0 2.8 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase RhoGAP PF00620.22 EKE37576.1 - 3.8e-12 46.0 2.7 7.2e-12 45.1 1.3 1.9 1 1 0 1 1 1 1 RhoGAP domain APS_kinase PF01583.15 EKE37576.1 - 0.07 12.7 0.0 1.4 8.5 0.0 2.6 3 0 0 3 3 3 0 Adenylylsulphate kinase PQ-loop PF04193.9 EKE37577.1 - 4.5e-33 112.5 16.4 1.4e-17 62.9 1.3 2.7 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EKE37577.1 - 0.0025 17.6 0.8 0.0025 17.6 0.5 3.2 3 2 1 4 4 4 1 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 EKE37577.1 - 0.17 12.3 11.5 11 6.4 0.0 4.0 4 0 0 4 4 4 0 ER lumen protein retaining receptor DUF2198 PF09964.4 EKE37577.1 - 0.4 10.4 8.9 6.7 6.5 0.0 4.6 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2198) NDUF_B6 PF09782.4 EKE37577.1 - 1.3 8.8 5.2 0.55 10.0 0.6 2.2 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Spore_III_AB PF09548.5 EKE37578.1 - 0.058 13.1 1.0 0.078 12.7 0.7 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) tRNA_synt_1c_R1 PF04558.10 EKE37578.1 - 0.082 12.4 0.2 0.83 9.1 0.0 2.0 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Tyr-DNA_phospho PF06087.7 EKE37579.1 - 1.7e-61 208.2 1.7 1.9e-60 204.7 1.1 1.9 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EKE37579.1 - 0.0023 17.6 0.1 0.045 13.5 0.0 2.5 2 1 0 2 2 2 1 PLD-like domain C2 PF00168.25 EKE37580.1 - 6.9e-09 35.4 0.8 4.3e-08 32.8 0.5 2.3 1 1 0 1 1 1 1 C2 domain zf-DHHC PF01529.15 EKE37581.1 - 5.7e-32 110.4 18.4 5.7e-32 110.4 12.8 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase LRV_FeS PF05484.6 EKE37581.1 - 0.046 13.3 3.5 0.094 12.3 2.5 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster Thioredoxin_7 PF13899.1 EKE37582.1 - 1.3e-15 57.1 0.0 1.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.10 EKE37582.1 - 0.098 12.3 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Spt4 PF06093.8 EKE37583.1 - 1.2e-15 57.1 1.0 1.5e-15 56.7 0.7 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger AMP-binding PF00501.23 EKE37584.1 - 3.3e-73 246.4 0.0 4e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PUF PF00806.14 EKE37585.1 - 2.1e-53 174.8 17.6 2.1e-09 36.3 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TAN PF11640.3 EKE37585.1 - 0.0086 15.8 0.1 0.05 13.3 0.1 2.4 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Rotamase_3 PF13616.1 EKE37585.1 - 0.53 10.5 8.6 12 6.1 0.1 4.4 4 1 1 5 5 5 0 PPIC-type PPIASE domain LMBR1 PF04791.11 EKE37587.1 - 0.8 8.2 8.5 1.1 7.8 5.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PLRV_ORF5 PF01690.12 EKE37587.1 - 3.5 6.6 16.7 4.9 6.1 11.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Sybindin PF04099.7 EKE37590.1 - 1.1e-33 115.9 0.5 1.2e-33 115.7 0.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EKE37590.1 - 3.4e-07 30.1 0.3 1.2e-06 28.3 0.2 1.9 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Yqai PF09466.5 EKE37591.1 - 0.1 12.6 0.4 0.56 10.2 0.1 2.2 2 0 0 2 2 2 0 Hypothetical protein Yqai A_thal_3526 PF09713.5 EKE37592.1 - 4.3e-08 33.1 0.3 6.3e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) Metallophos PF00149.23 EKE37593.1 - 5.1e-30 104.3 0.8 1.2e-29 103.1 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE37593.1 - 0.0035 17.1 0.0 0.0098 15.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_2 PF00152.15 EKE37594.1 - 2e-77 260.2 0.0 2.8e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKE37594.1 - 1.2e-11 44.3 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EKE37594.1 - 0.038 13.1 0.0 0.61 9.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF4131 PF13567.1 EKE37596.1 - 0.58 9.5 13.6 1.7 8.0 3.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M24 PF00557.19 EKE37598.1 - 2e-41 141.8 0.0 2.5e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2683 PF10884.3 EKE37598.1 - 0.082 12.8 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Ribosomal_S21e PF01249.13 EKE37599.1 - 5.5e-23 80.7 0.0 6e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e AIG1 PF04548.11 EKE37601.1 - 0.0056 15.8 1.6 0.0081 15.2 0.1 1.8 1 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 EKE37601.1 - 0.0091 15.9 0.7 0.013 15.4 0.5 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sigma54_activat PF00158.21 EKE37601.1 - 0.012 15.1 0.2 0.044 13.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.1 EKE37601.1 - 0.034 14.3 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_ligase_OB_2 PF14743.1 EKE37601.1 - 0.062 12.9 2.3 3.5 7.3 0.2 2.4 2 0 0 2 2 2 0 DNA ligase OB-like domain Zeta_toxin PF06414.7 EKE37601.1 - 0.063 12.3 0.1 3.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 EKE37601.1 - 0.12 12.7 2.6 0.24 11.7 1.8 1.7 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 EKE37601.1 - 0.22 10.4 3.5 0.37 9.6 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EKE37601.1 - 0.22 10.3 0.9 0.39 9.5 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein GBP PF02263.14 EKE37601.1 - 0.27 10.2 1.6 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Chloroplast_duf PF14476.1 EKE37601.1 - 0.48 9.1 2.9 0.74 8.5 2.0 1.2 1 0 0 1 1 1 0 Petal formation-expressed Miro PF08477.8 EKE37601.1 - 0.5 10.8 2.9 0.89 10.0 0.9 2.2 1 1 1 2 2 2 0 Miro-like protein DUF1469 PF07332.6 EKE37601.1 - 1.3 8.7 13.3 1.9 8.2 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) ResIII PF04851.10 EKE37601.1 - 2.7 7.7 7.9 37 4.0 5.6 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DNA_topoisoIV PF00521.15 EKE37602.1 - 3.4e-123 411.6 0.2 3.4e-123 411.6 0.1 2.1 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EKE37602.1 - 6.7e-34 116.5 0.8 2.6e-33 114.6 0.1 2.3 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EKE37602.1 - 2e-11 43.7 0.0 2.7e-10 40.1 0.0 2.8 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EKE37602.1 - 5.1e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DOCK-C2 PF14429.1 EKE37603.1 - 5.2e-41 140.3 6.7 1.7e-40 138.6 4.6 2.0 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EKE37603.1 - 1.7e-31 108.8 6.0 3.1e-31 108.0 0.1 3.1 2 0 0 2 2 2 1 Dedicator of cytokinesis ETC_C1_NDUFA5 PF04716.9 EKE37604.1 - 0.012 15.1 0.1 0.043 13.3 0.0 1.9 1 0 0 1 1 1 0 ETC complex I subunit conserved region DUF3658 PF12395.3 EKE37604.1 - 0.027 14.0 2.2 0.046 13.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function PBP_dimer PF03717.10 EKE37604.1 - 3.7 7.5 9.6 1.6 8.7 4.8 1.7 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain UPF0160 PF03690.8 EKE37605.1 - 1.2e-47 162.8 0.0 1.7e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) MCPsignal PF00015.16 EKE37606.1 - 0.0012 18.3 10.7 0.25 10.8 2.7 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE_C PF12352.3 EKE37606.1 - 0.0018 18.3 0.3 0.26 11.3 0.0 3.7 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 EKE37606.1 - 0.0064 16.2 22.1 0.034 13.9 3.9 4.0 1 1 2 4 4 4 3 Laminin Domain II Vps53_N PF04100.7 EKE37606.1 - 0.015 14.1 0.4 0.015 14.1 0.3 2.2 1 1 1 2 2 2 0 Vps53-like, N-terminal YjcZ PF13990.1 EKE37606.1 - 0.026 13.6 5.0 0.03 13.4 1.7 2.1 1 1 1 2 2 2 0 YjcZ-like protein Baculo_PEP_C PF04513.7 EKE37606.1 - 0.03 14.1 6.5 1.9 8.2 1.3 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ISG65-75 PF11727.3 EKE37606.1 - 0.066 12.2 26.7 0.058 12.4 0.2 3.4 1 1 3 4 4 4 0 Invariant surface glycoprotein ATP-synt_B PF00430.13 EKE37606.1 - 0.067 12.9 12.9 1.2 8.8 5.5 2.6 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) RmuC PF02646.11 EKE37606.1 - 0.091 11.5 19.7 0.46 9.2 0.3 3.5 2 1 2 4 4 4 0 RmuC family DegS PF05384.6 EKE37606.1 - 0.098 11.8 5.6 1.5 8.0 1.5 2.3 2 0 0 2 2 2 0 Sensor protein DegS DUF2580 PF10824.3 EKE37606.1 - 0.12 12.7 2.3 0.43 10.9 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) DUF948 PF06103.6 EKE37606.1 - 0.12 12.1 20.1 0.076 12.8 4.9 3.8 1 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.11 EKE37606.1 - 0.13 12.2 7.1 1.7 8.7 0.2 3.3 2 2 1 3 3 3 0 Flagellar FliJ protein Fib_alpha PF08702.5 EKE37606.1 - 0.17 12.0 12.3 0.058 13.5 0.5 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF883 PF05957.8 EKE37606.1 - 0.23 11.8 7.7 1.1 9.6 0.9 3.4 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF883) DUF607 PF04678.8 EKE37606.1 - 0.24 11.2 2.9 9.5 6.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF607 C9orf72-like PF15019.1 EKE37606.1 - 0.27 10.4 1.8 8.2 5.5 0.1 2.2 2 0 0 2 2 2 0 C9orf72-like protein family DUF4241 PF14025.1 EKE37606.1 - 0.28 10.9 5.0 0.16 11.7 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) WXG100 PF06013.7 EKE37606.1 - 0.43 10.6 8.4 11 6.0 1.1 4.1 1 1 4 5 5 5 0 Proteins of 100 residues with WXG DUF3140 PF11338.3 EKE37606.1 - 0.47 10.6 4.8 0.22 11.6 0.8 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF3140) DUF1993 PF09351.5 EKE37606.1 - 0.6 10.0 5.1 0.98 9.3 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Seryl_tRNA_N PF02403.17 EKE37606.1 - 0.7 9.9 16.3 0.52 10.3 3.6 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2130 PF09903.4 EKE37606.1 - 0.74 8.5 22.7 0.29 9.8 3.1 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) PHA_synth_III_E PF09712.5 EKE37606.1 - 1.9 7.8 7.3 7.5 5.8 2.6 2.7 1 1 2 3 3 3 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) MitMem_reg PF13012.1 EKE37606.1 - 2.2 8.3 8.0 2.9e+02 1.5 5.5 2.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Lebercilin PF15619.1 EKE37606.1 - 2.2 7.6 12.1 0.25 10.7 2.7 2.4 3 0 0 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease PRKCSH-like PF12999.2 EKE37606.1 - 2.4 7.7 14.0 1.2 8.7 3.6 2.6 1 1 0 2 2 2 0 Glucosidase II beta subunit-like DUF2408 PF10303.4 EKE37606.1 - 2.9 8.0 17.7 0.38 10.8 4.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) DUF1798 PF08807.5 EKE37606.1 - 4.2 7.1 10.1 3.7 7.2 1.4 2.4 1 1 1 2 2 2 0 Bacterial domain of unknown function (DUF1798) Gp-FAR-1 PF05823.7 EKE37606.1 - 6.4 6.7 16.5 12 5.8 5.3 2.5 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PRANC PF09372.5 EKE37606.1 - 7.2 6.6 8.7 1.8 8.5 1.6 2.7 3 1 0 3 3 2 0 PRANC domain DUF2514 PF10721.4 EKE37606.1 - 7.3 6.2 10.3 0.21 11.2 2.1 2.1 3 1 1 4 4 2 0 Protein of unknown function (DUF2514) DUF3810 PF12725.2 EKE37606.1 - 9.6 5.0 10.3 7.3 5.3 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF1191 PF06697.7 EKE37607.1 - 0.0046 15.8 0.0 0.008 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Peptidase_S41 PF03572.13 EKE37607.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Herpes_UL45 PF05473.7 EKE37607.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 UL45 protein DUF1517 PF07466.6 EKE37607.1 - 0.013 14.4 0.3 0.025 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF4194 PF13835.1 EKE37607.1 - 0.035 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) DUF4349 PF14257.1 EKE37607.1 - 0.052 12.7 0.0 4.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Pkinase_Tyr PF07714.12 EKE37611.1 - 3.9e-38 131.0 0.2 1.6e-37 128.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37611.1 - 1.8e-36 125.6 0.3 1.7e-35 122.4 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Myotub-related PF06602.9 EKE37611.1 - 2.8e-20 72.4 3.1 6.5e-20 71.2 2.2 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain LRR_4 PF12799.2 EKE37611.1 - 4.6e-12 45.2 34.4 0.00015 21.2 4.3 6.7 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE37611.1 - 1.6e-10 40.5 27.1 3.9e-05 23.3 0.5 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EKE37611.1 - 9.1e-09 34.1 25.7 0.14 12.2 0.2 9.0 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 EKE37611.1 - 1.7e-05 24.2 15.7 4.5 7.9 0.1 7.9 7 0 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 EKE37611.1 - 0.027 14.4 27.9 29 5.1 0.1 9.4 8 1 1 9 9 9 0 Leucine Rich repeat APH PF01636.18 EKE37611.1 - 2.2 7.9 1.0 45 3.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family SporV_AA PF12164.3 EKE37612.1 - 0.026 14.4 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 Stage V sporulation protein AA MyTH4 PF00784.12 EKE37613.1 - 0.041 13.8 3.3 0.11 12.4 0.2 2.6 1 1 1 2 2 2 0 MyTH4 domain ING PF12998.2 EKE37613.1 - 0.22 11.8 12.2 0.048 13.9 4.9 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding RapA_C PF12137.3 EKE37613.1 - 0.3 9.8 9.2 0.036 12.8 2.8 1.9 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal DUF3482 PF11981.3 EKE37613.1 - 0.39 9.9 2.6 0.55 9.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Med21 PF11221.3 EKE37613.1 - 1.7 8.6 10.6 0.26 11.2 1.0 2.5 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF1911 PF08929.5 EKE37613.1 - 3.5 8.3 8.8 2.1 9.0 0.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1911) Phasin PF05597.6 EKE37613.1 - 3.6 7.3 12.8 0.94 9.2 5.4 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AAA PF00004.24 EKE37614.1 - 3.7e-43 146.8 0.0 7.6e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKE37614.1 - 1.1e-06 28.7 0.1 0.00014 21.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKE37614.1 - 1.4e-06 28.3 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EKE37614.1 - 1.8e-05 23.8 0.0 3.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKE37614.1 - 2.4e-05 24.3 0.0 0.00014 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EKE37614.1 - 3.4e-05 23.6 0.1 0.0002 21.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EKE37614.1 - 3.5e-05 22.8 0.0 7e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EKE37614.1 - 0.00012 22.8 0.4 0.00053 20.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EKE37614.1 - 0.00022 21.1 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EKE37614.1 - 0.00047 19.1 0.0 0.042 12.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.12 EKE37614.1 - 0.00082 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EKE37614.1 - 0.0013 18.3 0.3 0.0028 17.3 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EKE37614.1 - 0.0022 17.1 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 EKE37614.1 - 0.0022 16.7 0.0 0.0046 15.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EKE37614.1 - 0.0023 17.8 0.0 0.0053 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EKE37614.1 - 0.0024 17.5 0.1 0.063 12.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EKE37614.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE37614.1 - 0.0047 17.2 3.5 0.0051 17.1 0.2 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EKE37614.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 EKE37614.1 - 0.0059 15.7 0.2 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EKE37614.1 - 0.0098 15.4 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EKE37614.1 - 0.014 14.6 0.1 0.066 12.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 EKE37614.1 - 0.017 14.8 0.3 0.18 11.4 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EKE37614.1 - 0.023 14.7 0.0 0.087 12.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 EKE37614.1 - 0.023 14.0 0.6 0.18 11.2 0.1 2.2 1 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EKE37614.1 - 0.028 13.5 0.1 0.77 8.8 0.0 2.3 1 1 1 2 2 2 0 KaiC RbsD_FucU PF05025.8 EKE37614.1 - 0.041 14.1 0.1 9 6.6 0.0 2.6 2 0 0 2 2 2 0 RbsD / FucU transport protein family ABC_tran PF00005.22 EKE37614.1 - 0.044 14.0 0.5 0.23 11.7 0.1 2.6 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.7 EKE37614.1 - 0.066 12.8 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain GTSE1_N PF15259.1 EKE37614.1 - 0.07 13.0 0.4 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Parvo_NS1 PF01057.12 EKE37614.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF1090 PF06476.7 EKE37614.1 - 0.19 11.4 2.7 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) NTPase_1 PF03266.10 EKE37614.1 - 0.38 10.4 3.0 2.2 7.9 0.0 3.2 2 2 0 3 3 3 0 NTPase EMP24_GP25L PF01105.19 EKE37615.1 - 0.014 15.0 1.4 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Imm35 PF15581.1 EKE37615.1 - 0.13 12.2 0.7 2 8.4 0.3 2.4 2 0 0 2 2 2 0 Immunity protein 35 Pkinase_Tyr PF07714.12 EKE37617.1 - 1.4e-49 168.5 0.3 2.1e-49 167.9 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37617.1 - 1.6e-49 168.3 0.7 1.6e-49 168.3 0.5 1.8 2 0 0 2 2 2 1 Protein kinase domain VSP PF03302.8 EKE37617.1 - 2.2e-05 23.3 42.1 2.2e-05 23.3 29.2 10.2 1 1 5 8 8 8 3 Giardia variant-specific surface protein FeThRed_A PF02941.10 EKE37617.1 - 0.29 11.0 0.0 0.69 9.8 0.0 1.6 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain TMEM154 PF15102.1 EKE37617.1 - 8.8 6.0 8.0 0.13 11.9 0.2 1.9 2 0 0 2 2 2 0 TMEM154 protein family RasGEF PF00617.14 EKE37618.1 - 1.4e-14 54.2 6.7 1.4e-14 54.2 4.6 2.3 2 1 0 2 2 2 1 RasGEF domain DnaJ PF00226.26 EKE37619.1 - 1.4e-24 85.6 3.2 2.1e-24 85.0 2.2 1.3 1 0 0 1 1 1 1 DnaJ domain CSD PF00313.17 EKE37620.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain PPDFL PF15060.1 EKE37621.1 - 0.11 12.4 0.5 0.3 11.1 0.3 1.7 1 0 0 1 1 1 0 Differentiation and proliferation regulator Peptidase_C1 PF00112.18 EKE37622.1 - 7.1e-33 114.3 0.0 1.1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Transaldolase PF00923.14 EKE37622.1 - 0.011 14.9 0.0 0.031 13.4 0.0 1.6 2 0 0 2 2 2 0 Transaldolase Inhibitor_I29 PF08246.7 EKE37622.1 - 0.012 15.8 1.5 0.025 14.8 1.1 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Mga PF05043.8 EKE37622.1 - 0.057 13.7 0.8 0.12 12.6 0.3 1.6 1 1 0 1 1 1 0 Mga helix-turn-helix domain Motile_Sperm PF00635.21 EKE37623.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 MSP (Major sperm protein) domain LIM PF00412.17 EKE37624.1 - 8.9e-13 48.1 23.3 2.2e-09 37.2 6.1 3.8 3 1 1 4 4 4 2 LIM domain zinc_ribbon_2 PF13240.1 EKE37624.1 - 2.2e-09 36.5 27.2 6.5e-09 35.0 3.3 4.5 4 0 0 4 4 4 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 EKE37624.1 - 5.1e-09 35.0 28.6 9.8e-09 34.1 3.8 4.4 4 0 0 4 4 4 2 zinc-ribbon domain DZR PF12773.2 EKE37624.1 - 1.6e-08 34.2 20.2 0.017 14.9 14.0 3.4 1 1 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.1 EKE37624.1 - 8.4e-05 22.1 13.5 0.11 12.2 0.1 5.3 5 1 0 5 5 5 2 Nudix N-terminal zf-NADH-PPase PF09297.6 EKE37624.1 - 0.027 13.9 21.4 0.14 11.7 0.1 5.4 6 0 0 6 6 6 0 NADH pyrophosphatase zinc ribbon domain DUF4428 PF14471.1 EKE37624.1 - 0.038 13.7 17.7 0.31 10.8 3.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) zf-C3HC4_3 PF13920.1 EKE37624.1 - 0.052 13.2 0.6 0.052 13.2 0.4 3.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.4 EKE37624.1 - 0.098 12.5 0.4 0.098 12.5 0.2 3.5 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain UPF0547 PF10571.4 EKE37624.1 - 0.16 11.6 0.4 0.16 11.6 0.3 5.1 4 2 0 5 5 5 0 Uncharacterised protein family UPF0547 Prok-RING_1 PF14446.1 EKE37624.1 - 0.18 11.5 27.8 0.2 11.3 1.0 4.8 2 1 2 4 4 4 0 Prokaryotic RING finger family 1 Cript PF10235.4 EKE37624.1 - 0.19 12.1 21.0 2 8.8 0.9 4.1 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT MTBP_C PF14920.1 EKE37624.1 - 0.25 10.7 2.7 0.4 10.1 1.8 1.4 1 1 0 1 1 1 0 MDM2-binding Ogr_Delta PF04606.7 EKE37624.1 - 0.38 10.4 0.0 0.38 10.4 0.0 4.0 5 0 0 5 5 5 0 Ogr/Delta-like zinc finger GFA PF04828.9 EKE37624.1 - 0.77 9.7 21.1 0.66 9.9 0.1 4.9 1 1 4 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme DUF2256 PF10013.4 EKE37624.1 - 1.1 9.1 0.0 1.1 9.1 0.0 4.3 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.3 EKE37624.1 - 1.2 9.2 9.6 0.59 10.2 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3268) YhfH PF14149.1 EKE37624.1 - 2 8.2 26.1 6.6 6.6 3.9 5.7 3 2 2 5 5 5 0 YhfH-like protein FYVE_2 PF02318.11 EKE37624.1 - 2.5 7.9 12.3 0.25 11.2 4.2 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger zf-TFIIB PF13453.1 EKE37624.1 - 3.2 7.0 14.2 3 7.1 0.0 4.7 5 0 0 5 5 5 0 Transcription factor zinc-finger zf-C2H2 PF00096.21 EKE37624.1 - 3.4 8.1 22.1 1.6 9.2 0.2 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 EKE37624.1 - 4 7.4 25.2 9.1 6.3 0.2 5.1 3 2 1 4 4 4 0 Zinc ribbon domain FYVE PF01363.16 EKE37624.1 - 7 6.6 23.3 4.7 7.1 2.4 3.6 1 1 1 2 2 2 0 FYVE zinc finger C1_2 PF03107.11 EKE37624.1 - 7.4 6.7 11.6 0.88 9.7 0.2 3.8 4 0 0 4 4 4 0 C1 domain TF_Zn_Ribbon PF08271.7 EKE37624.1 - 8.9 5.7 18.9 5.5 6.3 0.1 4.8 5 0 0 5 5 5 0 TFIIB zinc-binding TMEM154 PF15102.1 EKE37625.1 - 0.0031 17.2 1.9 0.0031 17.2 1.3 1.8 2 0 0 2 2 2 1 TMEM154 protein family AAA PF00004.24 EKE37626.1 - 1.3e-28 99.8 0.0 4.2e-28 98.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE37626.1 - 4.1e-05 23.6 0.1 0.00016 21.7 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EKE37626.1 - 0.00013 20.9 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EKE37626.1 - 0.00015 21.9 0.4 0.016 15.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 EKE37626.1 - 0.00031 20.2 0.2 0.36 10.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain NACHT PF05729.7 EKE37626.1 - 0.002 17.7 0.1 0.22 11.1 0.0 2.4 1 1 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EKE37626.1 - 0.0023 17.6 0.1 0.0096 15.6 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EKE37626.1 - 0.0029 17.5 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EKE37626.1 - 0.005 15.5 0.0 0.0077 14.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EKE37626.1 - 0.0058 17.4 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKE37626.1 - 0.0058 16.7 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 EKE37626.1 - 0.0059 16.8 0.0 0.019 15.2 0.0 1.8 2 0 0 2 2 1 1 ABC transporter AAA_5 PF07728.9 EKE37626.1 - 0.0059 16.3 0.0 0.049 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EKE37626.1 - 0.025 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EKE37626.1 - 0.038 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EKE37626.1 - 0.041 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EKE37626.1 - 0.055 13.7 3.2 0.22 11.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.13 EKE37626.1 - 0.073 12.7 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein RuvB_N PF05496.7 EKE37626.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EKE37626.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_S27e PF01667.12 EKE37628.1 - 1.3e-28 98.2 3.9 1.5e-28 98.0 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EKE37628.1 - 3.6e-05 22.9 0.2 5e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EKE37628.1 - 0.00031 19.8 3.5 0.0017 17.4 2.4 2.0 1 1 0 1 1 1 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EKE37628.1 - 0.0011 18.6 0.3 0.0015 18.1 0.2 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 EKE37628.1 - 0.0029 17.8 1.7 0.0035 17.6 1.2 1.3 1 1 0 1 1 1 1 Restriction alleviation protein Lar DZR PF12773.2 EKE37628.1 - 0.0047 16.7 5.0 0.018 14.8 3.5 1.8 1 1 1 2 2 2 1 Double zinc ribbon zf-FPG_IleRS PF06827.9 EKE37628.1 - 0.0084 15.7 1.0 0.07 12.7 0.1 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS HypA PF01155.14 EKE37628.1 - 0.012 15.3 0.8 0.014 15.1 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 EKE37628.1 - 0.013 15.3 1.8 0.02 14.6 1.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Yippee-Mis18 PF03226.9 EKE37628.1 - 0.015 15.3 1.2 0.093 12.7 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PhnA_Zn_Ribbon PF08274.7 EKE37628.1 - 0.015 15.0 0.3 0.025 14.3 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.1 EKE37628.1 - 0.019 14.4 7.8 1.3 8.6 5.3 2.4 1 1 1 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EKE37628.1 - 0.021 14.7 3.8 0.067 13.1 2.7 1.8 1 1 0 1 1 1 0 Zinc ribbon domain IBR PF01485.16 EKE37628.1 - 0.022 14.6 0.5 0.022 14.6 0.4 1.4 2 0 0 2 2 1 0 IBR domain Auto_anti-p27 PF06677.7 EKE37628.1 - 0.026 14.2 3.3 2.9 7.7 0.3 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mu-like_Com PF10122.4 EKE37628.1 - 0.031 13.3 3.8 0.033 13.2 0.1 2.1 1 1 0 2 2 2 0 Mu-like prophage protein Com Ribosomal_S27 PF01599.14 EKE37628.1 - 0.032 14.0 0.9 0.061 13.1 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein S27a zf-CCHC PF00098.18 EKE37628.1 - 0.034 14.0 3.4 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle A2L_zn_ribbon PF08792.5 EKE37628.1 - 0.04 13.3 2.7 1.1 8.7 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF2752 PF10825.3 EKE37628.1 - 0.055 13.5 0.7 0.071 13.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) zf-Mss51 PF13824.1 EKE37628.1 - 0.063 13.1 3.3 1.2 9.0 2.5 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TFIIS_C PF01096.13 EKE37628.1 - 0.068 12.8 0.5 0.068 12.8 0.3 2.4 2 1 1 3 3 2 0 Transcription factor S-II (TFIIS) HECT_2 PF09814.4 EKE37628.1 - 0.078 11.6 0.2 0.092 11.4 0.2 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding ADK_lid PF05191.9 EKE37628.1 - 0.12 12.0 3.5 1.3 8.7 2.4 2.2 1 1 0 1 1 1 0 Adenylate kinase, active site lid Nop10p PF04135.7 EKE37628.1 - 0.12 12.0 0.8 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family DUF866 PF05907.8 EKE37628.1 - 0.13 11.7 1.1 0.16 11.4 0.7 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-C2H2_4 PF13894.1 EKE37628.1 - 0.13 12.6 5.0 0.2 12.0 0.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_6 PF14599.1 EKE37628.1 - 0.14 11.9 1.9 0.59 9.9 1.3 1.9 1 1 0 1 1 1 0 Zinc-ribbon Zn_Tnp_IS91 PF14319.1 EKE37628.1 - 0.15 11.6 1.5 0.16 11.4 1.0 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-TFIIB PF13453.1 EKE37628.1 - 0.16 11.1 3.2 0.32 10.2 2.2 1.5 1 1 0 1 1 1 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.1 EKE37628.1 - 0.16 11.6 5.9 0.93 9.2 0.1 2.6 3 0 0 3 3 2 0 zinc-ribbon domain FYVE PF01363.16 EKE37628.1 - 0.17 11.7 4.2 0.24 11.3 2.9 1.3 1 1 0 1 1 1 0 FYVE zinc finger Nudix_N_2 PF14803.1 EKE37628.1 - 0.18 11.5 4.4 4.6 7.0 0.3 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-C2H2 PF00096.21 EKE37628.1 - 0.21 12.0 2.6 2 8.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-B_box PF00643.19 EKE37628.1 - 0.21 11.4 2.5 0.49 10.3 1.8 1.6 1 1 0 1 1 1 0 B-box zinc finger DUF4182 PF13790.1 EKE37628.1 - 0.22 11.3 1.4 4.9 7.0 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4182) zf-CCHC_3 PF13917.1 EKE37628.1 - 0.23 11.1 0.5 0.23 11.1 0.3 2.6 3 0 0 3 3 3 0 Zinc knuckle Zn_ribbon_recom PF13408.1 EKE37628.1 - 0.37 11.0 4.6 18 5.6 3.2 2.2 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.7 EKE37628.1 - 0.4 10.5 4.4 0.81 9.5 3.1 1.7 1 1 0 1 1 1 0 zinc-ribbons DUF1936 PF09151.5 EKE37628.1 - 0.42 10.1 3.7 5.3 6.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) zf-H2C2_2 PF13465.1 EKE37628.1 - 0.43 10.9 0.2 0.43 10.9 0.1 2.3 3 0 0 3 3 2 0 Zinc-finger double domain zf-NADH-PPase PF09297.6 EKE37628.1 - 0.61 9.6 5.3 1.6 8.3 2.9 2.2 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EKE37628.1 - 0.63 9.5 5.4 4.3 6.9 3.8 2.1 1 1 0 1 1 1 0 InsA N-terminal domain zf-C4_Topoisom PF01396.14 EKE37628.1 - 0.79 9.2 9.1 0.81 9.2 0.3 2.5 3 0 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger zf-HIT PF04438.11 EKE37628.1 - 0.79 9.4 4.2 2.8 7.6 0.1 2.4 3 0 0 3 3 2 0 HIT zinc finger Prok-RING_1 PF14446.1 EKE37628.1 - 0.85 9.3 3.8 5.6 6.7 2.7 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-IS66 PF13005.2 EKE37628.1 - 0.86 9.6 5.1 1.8 8.6 0.1 2.2 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF1610 PF07754.6 EKE37628.1 - 0.92 9.6 6.1 3.2 7.9 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) CpXC PF14353.1 EKE37628.1 - 1 9.3 3.2 2.1 8.3 0.1 2.1 1 1 2 3 3 3 0 CpXC protein GATA PF00320.22 EKE37628.1 - 1.1 8.6 4.7 5.2 6.4 3.3 2.0 1 1 0 1 1 1 0 GATA zinc finger DUF2082 PF09855.4 EKE37628.1 - 1.4 8.8 5.1 2.1 8.2 0.4 2.3 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-tcix PF14952.1 EKE37628.1 - 2.3 7.6 8.3 0.42 10.0 3.0 1.9 2 1 0 2 2 1 0 Putative treble-clef, zinc-finger, Zn-binding DNA_RNApol_7kD PF03604.8 EKE37628.1 - 3.3 7.2 8.4 8.9 5.8 3.6 2.7 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 EKE37628.1 - 3.5 7.3 10.0 28 4.4 4.6 2.6 2 1 0 2 2 1 0 zinc-ribbon domain zf-ISL3 PF14690.1 EKE37628.1 - 6.1 6.9 8.6 1.6 8.8 0.3 2.3 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rap_GAP PF02145.10 EKE37629.1 - 7.4e-45 152.6 2.7 1.2e-44 151.9 1.8 1.3 1 0 0 1 1 1 1 Rap/ran-GAP zf-DHHC PF01529.15 EKE37630.1 - 4.8e-33 113.9 22.5 4.8e-33 113.9 15.6 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 EKE37630.1 - 0.43 9.9 6.8 0.53 9.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1230 PF06799.6 EKE37630.1 - 0.79 9.5 7.4 1.4 8.7 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) Sdh_cyt PF01127.17 EKE37630.1 - 0.83 9.4 9.4 0.048 13.4 1.9 2.1 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit GTP_EFTU PF00009.22 EKE37631.1 - 3.5e-45 153.7 0.0 8.9e-45 152.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKE37631.1 - 5.6e-20 71.3 0.0 2.2e-18 66.2 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKE37631.1 - 3.4e-06 27.0 0.7 1.6e-05 24.9 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKE37631.1 - 0.00014 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4464 PF14713.1 EKE37631.1 - 0.0087 15.4 0.3 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) G-alpha PF00503.15 EKE37631.1 - 0.014 14.1 1.5 0.025 13.2 1.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DltD_C PF04914.7 EKE37631.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 DltD C-terminal region GTP_EFTU_D4 PF14578.1 EKE37631.1 - 0.02 14.4 0.2 0.067 12.8 0.1 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EKE37631.1 - 0.041 13.3 0.1 8.4 5.8 0.0 3.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PerC PF06069.6 EKE37633.1 - 0.032 14.2 0.0 0.098 12.7 0.0 1.7 1 1 1 2 2 2 0 PerC transcriptional activator Pkinase PF00069.20 EKE37634.1 - 1.6e-90 302.8 2.1 1.7e-53 181.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37634.1 - 3.6e-59 199.9 0.2 4.8e-31 107.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKE37634.1 - 3.9e-07 29.3 0.0 0.0029 16.5 0.0 2.5 2 1 0 2 2 2 2 Kinase-like AAA_11 PF13086.1 EKE37635.1 - 4.1e-64 216.3 10.0 4.1e-64 216.3 6.9 4.5 2 2 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EKE37635.1 - 1.1e-60 204.4 0.0 1.1e-60 204.4 0.0 3.8 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.1 EKE37635.1 - 3.6e-10 39.4 0.0 6.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKE37635.1 - 3.5e-06 26.7 0.0 0.00042 19.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EKE37635.1 - 0.00029 21.2 17.2 0.00029 21.2 11.9 5.0 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.1 EKE37635.1 - 0.0055 16.1 1.2 0.013 14.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 EKE37635.1 - 0.024 14.7 0.0 0.24 11.5 0.0 2.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RecR PF02132.10 EKE37636.1 - 0.045 13.1 0.8 0.14 11.6 0.6 1.7 1 0 0 1 1 1 0 RecR protein TRM PF02005.11 EKE37637.1 - 4.2e-110 368.2 0.0 5.1e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 EKE37637.1 - 0.02 15.4 0.0 0.043 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PhnA_Zn_Ribbon PF08274.7 EKE37637.1 - 0.02 14.6 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Methyltransf_31 PF13847.1 EKE37637.1 - 0.023 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PPP5 PF08321.7 EKE37637.1 - 0.025 14.6 0.0 0.083 12.9 0.0 1.9 1 0 0 1 1 1 0 PPP5 TPR repeat region Cons_hypoth95 PF03602.10 EKE37637.1 - 0.032 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2009 PF09418.5 EKE37639.1 - 3.5e-192 639.2 1.5 3.5e-192 639.2 1.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2009) Adaptin_N PF01602.15 EKE37641.1 - 8.4e-138 459.9 18.3 1e-137 459.7 12.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EKE37641.1 - 7.5e-22 78.0 8.9 1.9e-20 73.4 1.3 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EKE37641.1 - 4.3e-19 68.5 2.0 7.4e-11 42.1 0.0 4.3 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.17 EKE37641.1 - 4.5e-09 35.6 8.4 0.00097 19.0 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EKE37641.1 - 9.6e-08 32.2 1.0 0.005 17.2 0.0 5.7 5 1 1 6 6 6 2 HEAT-like repeat Cnd3 PF12719.2 EKE37641.1 - 3.3e-07 29.6 2.6 2.2e-06 26.8 0.4 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 EKE37641.1 - 0.0058 16.4 0.2 17 5.3 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EKE37641.1 - 0.02 14.2 8.9 2.8 7.2 0.0 4.9 4 1 2 6 6 6 0 CLASP N terminal DNA_alkylation PF08713.6 EKE37641.1 - 0.045 13.2 0.2 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 DNA alkylation repair enzyme Pkinase PF00069.20 EKE37642.1 - 2.1e-64 217.1 0.0 3.2e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37642.1 - 2.2e-46 158.0 0.0 3.4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Calpain_III PF01067.17 EKE37642.1 - 2.4e-37 127.8 1.3 1e-16 60.9 0.1 3.9 4 0 0 4 4 4 3 Calpain large subunit, domain III Kinase-like PF14531.1 EKE37642.1 - 1.1e-06 27.8 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pacs-1 PF10254.4 EKE37643.1 - 6.5e-10 38.2 9.0 3.1e-08 32.6 0.0 2.6 2 1 0 3 3 3 2 PACS-1 cytosolic sorting protein ORC3_N PF07034.6 EKE37643.1 - 0.049 12.6 0.3 0.049 12.6 0.2 2.3 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 3 N-terminus PPC PF04151.10 EKE37645.1 - 1.4e-06 29.1 0.9 1e-05 26.4 0.3 2.8 2 0 0 2 2 2 1 Bacterial pre-peptidase C-terminal domain DUF4384 PF14326.1 EKE37646.1 - 0.066 13.0 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) RRM_1 PF00076.17 EKE37647.1 - 3.5e-08 32.9 2.3 3.5e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37647.1 - 0.041 13.8 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YcbB PF08664.5 EKE37647.1 - 0.43 10.3 8.2 0.068 12.9 0.4 2.7 2 2 0 2 2 2 0 YcbB domain Allexi_40kDa PF05549.6 EKE37647.1 - 0.58 9.4 4.1 0.4 9.9 0.5 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein XH PF03469.9 EKE37647.1 - 0.76 9.4 10.6 0.25 10.9 4.6 2.2 2 1 0 2 2 2 0 XH domain SPRY PF00622.23 EKE37648.1 - 1.7e-13 50.7 0.2 2.4e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 SPRY domain DUF3818 PF12825.2 EKE37648.1 - 0.025 13.2 4.7 0.034 12.8 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Sybindin PF04099.7 EKE37648.1 - 0.041 13.5 0.4 0.28 10.8 0.1 2.4 2 1 1 3 3 3 0 Sybindin-like family Syntaxin-6_N PF09177.6 EKE37648.1 - 0.15 12.4 2.5 0.3 11.5 1.7 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EKE37648.1 - 0.22 11.3 6.9 2.6 7.9 4.8 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BBP1_N PF15271.1 EKE37649.1 - 7e-19 68.6 1.7 9e-19 68.2 1.2 1.1 1 0 0 1 1 1 1 Spindle pole body component BBP1, Mps2-binding protein DUF4294 PF14127.1 EKE37649.1 - 0.007 15.9 1.0 0.0094 15.5 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) Myb_DNA-bind_6 PF13921.1 EKE37649.1 - 0.0071 16.4 0.1 5.6 7.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain OmpH PF03938.9 EKE37649.1 - 0.032 14.1 2.2 0.037 13.9 1.5 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SRRM_C PF15230.1 EKE37649.1 - 0.11 12.6 0.8 0.19 11.8 0.6 1.3 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus SAC3_GANP PF03399.11 EKE37649.1 - 0.12 11.8 1.0 0.15 11.6 0.8 1.3 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family EMP24_GP25L PF01105.19 EKE37650.1 - 1e-17 64.4 0.1 1.2e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2207 PF09972.4 EKE37650.1 - 0.01 14.4 0.1 0.5 8.8 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ribosomal_L38e PF01781.13 EKE37652.1 - 2.2e-20 72.1 2.3 2.6e-20 71.9 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Lipase_3 PF01764.20 EKE37653.1 - 1.7e-21 76.3 0.0 3.9e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EKE37653.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sec10 PF07393.6 EKE37654.1 - 4.2e-53 180.6 21.3 1.9e-29 102.4 10.2 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec10 Occludin_ELL PF07303.8 EKE37654.1 - 0.039 14.6 0.7 0.039 14.6 0.5 4.4 4 1 2 6 6 6 0 Occludin homology domain COG5 PF10392.4 EKE37654.1 - 0.23 11.3 10.0 0.091 12.7 0.3 3.5 4 0 0 4 4 4 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EKE37654.1 - 0.51 10.1 11.6 0.17 11.7 0.1 3.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EKE37654.1 - 4.3 6.8 13.6 1.2 8.7 1.7 3.3 3 0 0 3 3 3 0 IncA protein DSPc PF00782.15 EKE37655.1 - 6e-38 129.4 0.2 2e-37 127.7 0.1 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 EKE37655.1 - 3.5e-18 64.7 26.6 3.5e-08 32.8 0.3 6.4 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE37655.1 - 6.5e-15 54.6 25.6 3.2e-07 29.9 2.2 5.3 2 2 3 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 EKE37655.1 - 0.00033 20.3 19.6 30 5.4 0.1 9.3 7 3 1 8 8 8 0 Leucine rich repeat Y_phosphatase PF00102.22 EKE37655.1 - 0.00036 19.9 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EKE37655.1 - 0.0017 17.7 0.1 0.0046 16.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family LRR_1 PF00560.28 EKE37655.1 - 0.0022 17.7 35.1 4.8 7.5 0.3 9.8 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.1 EKE37655.1 - 0.18 11.9 22.9 11 6.4 0.1 9.0 5 2 3 8 8 8 0 Leucine Rich repeat Y_phosphatase3 PF13350.1 EKE37655.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PDCD2_C PF04194.8 EKE37656.1 - 1.1e-19 70.5 2.2 1.5e-19 70.1 0.8 1.8 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Desulfoferrod_N PF06397.7 EKE37656.1 - 0.23 10.8 0.2 0.23 10.8 0.1 3.9 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain RecR PF02132.10 EKE37656.1 - 0.29 10.6 4.8 2.2 7.7 0.5 2.5 2 0 0 2 2 2 0 RecR protein DNA_pol3_delta2 PF13177.1 EKE37658.1 - 1.5e-18 66.9 2.0 1.8e-16 60.2 0.1 2.6 2 1 0 2 2 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EKE37658.1 - 2.2e-17 63.4 0.1 4.7e-17 62.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EKE37658.1 - 6.3e-12 45.3 0.8 3e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.10 EKE37658.1 - 8.3e-12 44.5 0.7 1.6e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EKE37658.1 - 1.5e-08 34.8 0.3 0.0019 18.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.8 EKE37658.1 - 2.8e-08 33.4 0.2 4.6e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EKE37658.1 - 4.9e-08 32.3 0.0 5.2e-06 25.6 0.0 2.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKE37658.1 - 8e-07 29.2 0.0 3.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EKE37658.1 - 5.9e-06 26.2 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EKE37658.1 - 7.5e-06 25.0 0.0 2e-05 23.6 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EKE37658.1 - 7.8e-06 25.6 0.2 1.5e-05 24.6 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE37658.1 - 1e-05 25.8 0.0 2.7e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EKE37658.1 - 1.3e-05 25.0 0.1 2.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EKE37658.1 - 2.7e-05 23.8 0.0 6.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EKE37658.1 - 5.1e-05 23.3 0.0 0.00016 21.7 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EKE37658.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NB-ARC PF00931.17 EKE37658.1 - 0.00023 20.1 0.1 0.0029 16.5 0.0 2.0 1 1 1 2 2 2 1 NB-ARC domain AAA_5 PF07728.9 EKE37658.1 - 0.00024 20.8 0.2 0.0024 17.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EKE37658.1 - 0.00046 19.4 0.0 0.032 13.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EKE37658.1 - 0.00058 20.6 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKE37658.1 - 0.00073 19.0 0.2 0.0052 16.2 0.1 2.4 1 1 0 1 1 1 1 AAA-like domain TIP49 PF06068.8 EKE37658.1 - 0.0009 18.0 0.1 0.02 13.6 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 EKE37658.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EKE37658.1 - 0.0024 17.3 0.2 0.0051 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EKE37658.1 - 0.0034 16.2 0.3 2 7.1 0.0 2.4 2 1 1 3 3 3 2 SNF2 family N-terminal domain AAA_33 PF13671.1 EKE37658.1 - 0.0054 16.6 0.1 0.015 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EKE37658.1 - 0.0068 15.6 0.5 0.63 9.2 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein FtsK_SpoIIIE PF01580.13 EKE37658.1 - 0.0071 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DEAD PF00270.24 EKE37658.1 - 0.0082 15.6 1.2 0.63 9.5 0.0 2.6 2 1 0 3 3 3 1 DEAD/DEAH box helicase DBI_PRT PF02277.12 EKE37658.1 - 0.019 14.0 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyltransferase RNA_helicase PF00910.17 EKE37658.1 - 0.021 14.9 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 EKE37658.1 - 0.023 13.5 0.1 0.093 11.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 EKE37658.1 - 0.023 13.7 0.9 0.57 9.2 0.2 2.5 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.6 EKE37658.1 - 0.024 14.2 0.0 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKE37658.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 EKE37658.1 - 0.06 12.9 0.0 0.25 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EKE37658.1 - 0.08 11.9 0.2 0.23 10.3 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EKE37658.1 - 0.083 12.6 0.2 1.6 8.4 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function DUF87 Fer4 PF00037.22 EKE37659.1 - 3e-11 42.3 14.0 5.2e-06 25.8 2.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EKE37659.1 - 2e-08 33.7 14.8 1.9e-05 24.3 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EKE37659.1 - 2.2e-07 31.0 13.9 4.5e-07 30.0 9.6 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EKE37659.1 - 2.5e-07 30.9 14.1 6.8e-07 29.5 9.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE37659.1 - 3.2e-07 29.8 16.0 0.0001 21.9 2.5 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EKE37659.1 - 3.4e-07 30.0 27.4 4.7e-05 23.1 11.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE37659.1 - 1.2e-06 28.1 15.8 1.7e-05 24.5 11.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKE37659.1 - 3.1e-06 27.0 15.4 2.2e-05 24.3 10.7 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EKE37659.1 - 2.1e-05 25.1 14.2 0.015 15.9 2.1 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 EKE37659.1 - 4.2e-05 23.5 16.5 0.0061 16.7 2.6 2.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EKE37659.1 - 4.7e-05 23.7 13.5 0.00038 20.8 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 EKE37659.1 - 8.6e-05 22.8 17.7 0.012 16.1 4.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EKE37659.1 - 0.00014 22.1 15.8 0.024 14.9 2.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Hormone_4 PF00220.12 EKE37659.1 - 0.044 13.4 1.5 9.1 6.2 0.0 3.0 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain zf-CXXC PF02008.15 EKE37659.1 - 0.83 9.5 14.8 2.8 7.8 2.7 2.1 1 1 1 2 2 2 0 CXXC zinc finger domain Fer4_13 PF13370.1 EKE37659.1 - 1.6 9.1 16.7 2.7 8.4 2.7 2.8 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 EKE37659.1 - 4.8 7.8 15.4 0.39 11.3 2.2 2.4 2 1 0 2 2 2 0 4Fe-4S single cluster domain ABC_tran PF00005.22 EKE37660.1 - 1.8e-30 106.0 0.1 2.9e-30 105.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKE37660.1 - 1.2e-06 28.7 4.8 7.9e-05 22.7 0.7 2.8 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EKE37660.1 - 0.00013 21.8 0.1 0.0024 17.7 0.1 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EKE37660.1 - 0.00074 18.8 1.8 0.0073 15.5 0.1 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EKE37660.1 - 0.034 13.3 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE37660.1 - 0.038 13.9 0.1 0.05 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EKE37660.1 - 0.1 12.1 0.7 0.18 11.3 0.5 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 EKE37660.1 - 0.1 11.0 0.1 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_17 PF13207.1 EKE37660.1 - 0.11 13.3 3.6 0.13 13.0 0.6 2.5 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EKE37660.1 - 0.14 12.5 0.4 0.14 12.5 0.3 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EKE37660.1 - 0.47 10.5 3.7 5.6 7.1 2.6 2.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKE37660.1 - 9.3 6.5 7.7 61 3.9 5.3 2.5 1 1 0 1 1 1 0 AAA domain DNA_pol3_a_NII PF11490.3 EKE37661.1 - 0.091 12.3 4.7 0.22 11.1 3.2 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Peptidase_S74 PF13884.1 EKE37663.1 - 5.1e-12 45.7 0.2 1.4e-11 44.3 0.1 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase RNA_pol_Rpb1_5 PF04998.12 EKE37663.1 - 0.97 8.6 6.5 0.35 10.0 1.9 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 MotA_ExbB PF01618.11 EKE37663.1 - 2 8.0 6.1 51 3.4 0.0 2.9 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Smr PF01713.16 EKE37664.1 - 3.1e-06 27.3 0.7 6.6e-06 26.2 0.0 1.9 3 0 0 3 3 3 1 Smr domain DUSP PF06337.7 EKE37664.1 - 0.035 14.4 0.3 0.11 12.8 0.0 1.9 1 1 1 2 2 2 0 DUSP domain DUF904 PF06005.7 EKE37664.1 - 1.8 8.9 7.6 1.2 9.5 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF904) CcoS PF03597.10 EKE37664.1 - 10 5.7 6.5 16 5.0 4.5 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Ras PF00071.17 EKE37665.1 - 8.3e-56 187.8 0.3 9.5e-56 187.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37665.1 - 5.6e-21 75.2 0.0 1e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE37665.1 - 5e-14 51.9 0.0 6.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE37665.1 - 1.6e-05 24.8 0.0 2.3e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE37665.1 - 3.7e-05 23.2 0.0 0.00064 19.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE37665.1 - 5.7e-05 22.3 0.1 8.9e-05 21.7 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE37665.1 - 0.00025 20.2 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EKE37665.1 - 0.0016 17.7 0.1 0.29 10.4 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EKE37665.1 - 0.0049 16.6 0.0 0.0077 16.0 0.0 1.4 1 1 0 1 1 1 1 Dynamin family AAA_5 PF07728.9 EKE37665.1 - 0.017 14.8 0.1 0.1 12.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EKE37665.1 - 0.088 12.7 0.1 0.26 11.2 0.0 1.9 1 1 1 3 3 3 0 AAA domain Rad51 PF08423.6 EKE37666.1 - 7.5e-22 77.4 0.1 8.3e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 EKE37666.1 - 2.2e-10 40.0 0.0 5.1e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 EKE37666.1 - 2.8e-08 33.3 0.0 7e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE37666.1 - 0.0025 17.5 0.2 0.0093 15.6 0.0 1.9 1 1 1 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 EKE37666.1 - 0.0027 18.0 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RecA PF00154.16 EKE37666.1 - 0.0029 16.7 0.0 0.0097 14.9 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 EKE37666.1 - 0.0031 17.6 0.0 0.0066 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE37666.1 - 0.004 17.4 0.1 0.017 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EKE37666.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EKE37666.1 - 0.016 16.0 0.0 0.028 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EKE37666.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Clat_adaptor_s PF01217.15 EKE37667.1 - 6.4e-14 51.8 1.6 7.8e-14 51.5 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 EKE37668.1 - 0.0011 18.1 0.3 0.0011 18.1 0.2 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Ectoine_synth PF06339.7 EKE37668.1 - 0.011 15.6 0.1 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Ectoine synthase Ribosomal_L31 PF01197.13 EKE37668.1 - 0.099 12.6 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L31 Utp11 PF03998.8 EKE37669.1 - 1.8e-19 70.5 26.6 7.7e-18 65.1 18.5 2.0 1 1 0 1 1 1 1 Utp11 protein Lipoprotein_20 PF13942.1 EKE37669.1 - 0.015 14.8 5.2 0.015 14.8 3.6 2.0 2 0 0 2 2 2 0 YfhG lipoprotein HTH_37 PF13744.1 EKE37669.1 - 2.5 7.9 11.3 0.34 10.7 0.5 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Spc24 PF08286.6 EKE37669.1 - 8.5 6.1 14.4 0.3 10.7 5.0 2.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Sedlin_N PF04628.8 EKE37670.1 - 1.6e-29 102.4 1.7 1.8e-29 102.2 1.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EKE37670.1 - 4.4e-10 39.4 0.7 5.9e-10 39.0 0.5 1.3 1 1 0 1 1 1 1 Sybindin-like family NTP_transferase PF00483.18 EKE37670.1 - 0.11 11.8 0.1 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase zf-UBR PF02207.15 EKE37671.1 - 3.8e-08 32.9 11.0 8.5e-08 31.8 7.6 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) EF_TS PF00889.14 EKE37671.1 - 4.7 6.4 6.1 28 3.9 0.0 3.1 3 0 0 3 3 3 0 Elongation factor TS DUF1900 PF08954.6 EKE37672.1 - 2.8e-33 114.3 0.1 3.7e-32 110.6 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1900) Gelsolin PF00626.17 EKE37672.1 - 6.7e-19 67.3 6.1 1.9e-05 24.2 0.2 5.0 5 0 0 5 5 5 3 Gelsolin repeat WD40 PF00400.27 EKE37672.1 - 4.2e-14 51.7 0.0 7.2e-07 28.8 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat VHP PF02209.14 EKE37672.1 - 5.5e-12 45.1 0.2 2.6e-11 43.0 0.2 2.3 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.24 EKE37672.1 - 2.6e-10 40.4 6.6 0.0062 16.7 0.2 4.3 3 0 0 3 3 3 3 PH domain DUF1899 PF08953.6 EKE37672.1 - 0.0023 17.5 0.8 0.0079 15.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) PH_11 PF15413.1 EKE37672.1 - 0.92 9.7 14.0 0.17 12.1 0.4 4.4 4 1 0 4 4 4 0 Pleckstrin homology domain HA2 PF04408.18 EKE37673.1 - 6.3e-28 96.7 0.9 3e-27 94.6 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EKE37673.1 - 1.4e-21 76.4 0.1 7e-21 74.1 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EKE37673.1 - 1.6e-13 50.2 0.4 8.1e-13 48.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE37673.1 - 3.4e-08 33.1 5.2 4e-08 32.9 0.5 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE37673.1 - 1.2e-05 25.4 0.6 3.7e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 EKE37673.1 - 3.6e-05 23.5 0.0 8.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EKE37673.1 - 0.0091 15.8 0.1 0.0091 15.8 0.0 4.5 3 1 1 4 4 3 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EKE37673.1 - 0.022 14.5 0.1 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EKE37673.1 - 0.023 15.0 2.4 0.023 15.0 1.7 5.3 2 2 0 3 3 1 0 AAA domain AAA_30 PF13604.1 EKE37673.1 - 0.041 13.4 5.2 0.044 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EKE37673.1 - 0.078 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thioredoxin_2 PF13098.1 EKE37673.1 - 0.15 12.2 3.4 15 5.8 0.1 2.8 2 0 0 2 2 2 0 Thioredoxin-like domain RNA_pol_N PF01194.12 EKE37674.1 - 2.4e-25 88.2 0.2 2.9e-25 88.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF2951 PF11166.3 EKE37675.1 - 7.5e-06 25.7 3.2 7.5e-06 25.7 2.2 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2951) SNARE PF05739.14 EKE37675.1 - 0.012 15.2 5.4 0.03 14.0 3.8 1.7 1 0 0 1 1 1 0 SNARE domain RAB3GAP2_N PF14655.1 EKE37675.1 - 0.014 14.3 0.4 0.022 13.7 0.3 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Retrotrans_gag PF03732.12 EKE37675.1 - 0.09 12.8 0.8 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Y_phosphatase3 PF13350.1 EKE37675.1 - 0.15 12.3 3.1 0.28 11.4 0.4 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family COG5 PF10392.4 EKE37675.1 - 0.71 9.8 8.1 1 9.3 0.5 2.6 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4026 PF13218.1 EKE37675.1 - 0.81 8.4 7.4 0.093 11.5 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4026) NPV_P10 PF05531.7 EKE37675.1 - 0.91 9.8 11.3 0.55 10.5 2.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EKE37675.1 - 1.1 8.9 13.6 1.4 8.6 3.2 2.2 2 0 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.7 EKE37675.1 - 1.7 8.4 6.5 0.96 9.2 1.6 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 EKE37675.1 - 2.4 8.3 20.9 6.1 7.0 1.6 3.6 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EKE37675.1 - 2.8 8.0 17.5 0.44 10.6 3.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EKE37675.1 - 3.6 7.5 9.0 3.2 7.6 1.7 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ING PF12998.2 EKE37675.1 - 4 7.7 16.9 0.7 10.1 2.3 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Nsp1_C PF05064.8 EKE37675.1 - 5.6 6.6 12.5 0.12 12.0 1.4 2.8 2 2 1 3 3 3 0 Nsp1-like C-terminal region MecA_N PF05223.6 EKE37675.1 - 6.1 6.9 9.3 0.66 10.0 0.8 2.6 2 1 1 3 3 3 0 NTF2-like N-terminal transpeptidase domain Syntaxin-6_N PF09177.6 EKE37675.1 - 9.9 6.6 15.1 8.5 6.8 3.6 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal IBR PF01485.16 EKE37676.1 - 1.1e-13 50.8 25.7 2.2e-09 37.0 5.8 5.9 4 1 0 4 4 4 2 IBR domain UBA PF00627.26 EKE37676.1 - 2.2e-05 24.1 0.0 0.00097 18.9 0.0 2.8 2 0 0 2 2 2 1 UBA/TS-N domain zf-C3HC4_2 PF13923.1 EKE37676.1 - 0.00018 21.4 9.9 0.00018 21.4 6.9 5.5 5 1 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE37676.1 - 0.00038 20.0 4.3 0.00038 20.0 3.0 6.5 5 2 1 6 6 6 3 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EKE37676.1 - 0.0022 17.8 3.5 0.0022 17.8 2.5 4.7 3 2 1 4 4 4 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 EKE37676.1 - 0.0085 15.9 4.8 0.0085 15.9 3.3 5.6 4 2 1 5 5 5 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EKE37676.1 - 0.017 14.9 10.3 0.017 14.9 7.1 5.1 4 2 0 4 4 4 0 Ring finger domain CHD5 PF04420.9 EKE37676.1 - 5.1 6.7 7.3 2 8.0 2.2 2.3 1 1 1 2 2 2 0 CHD5-like protein DUF4598 PF15370.1 EKE37677.1 - 2.8e-09 37.2 2.2 4.7e-09 36.5 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Sec62 PF03839.11 EKE37677.1 - 7.8 5.8 7.8 8.1 5.7 5.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Nop PF01798.13 EKE37678.1 - 4.8e-57 191.4 0.1 9.5e-57 190.5 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EKE37678.1 - 4.4e-21 74.4 4.6 4.4e-20 71.2 0.4 3.8 4 0 0 4 4 4 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EKE37678.1 - 2.8e-18 65.8 1.0 1e-17 64.0 0.7 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF1722 PF08349.6 EKE37678.1 - 0.041 13.7 2.1 0.25 11.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) DUF1778 PF08681.6 EKE37678.1 - 0.056 13.2 0.3 8.7 6.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) Ras PF00071.17 EKE37679.1 - 5.8e-53 178.5 1.0 7.3e-53 178.2 0.7 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE37679.1 - 2.1e-22 79.2 0.2 2.8e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE37679.1 - 7.1e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE37679.1 - 3e-09 36.5 0.1 2.2e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 EKE37679.1 - 1.7e-06 27.3 8.1 2.2e-06 27.0 5.6 1.0 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EKE37679.1 - 6.5e-05 22.1 0.1 0.00012 21.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EKE37679.1 - 8.3e-05 21.9 0.0 0.00031 20.0 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EKE37679.1 - 0.0001 21.8 0.2 0.13 11.7 0.1 2.4 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EKE37679.1 - 0.00027 20.8 0.0 0.00053 19.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE37679.1 - 0.00048 19.3 0.0 0.00077 18.7 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EKE37679.1 - 0.001 19.2 0.1 0.0039 17.3 0.0 1.8 1 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EKE37679.1 - 0.0016 17.2 0.1 1.2 7.7 0.1 2.1 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 EKE37679.1 - 0.003 17.7 0.2 0.0085 16.2 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EKE37679.1 - 0.0033 17.1 0.3 0.0075 15.9 0.0 1.6 1 1 0 1 1 1 1 NTPase MobB PF03205.9 EKE37679.1 - 0.0034 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EKE37679.1 - 0.0042 16.8 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EKE37679.1 - 0.0064 15.6 0.1 0.069 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE37679.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Septin PF00735.13 EKE37679.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Septin DBI_PRT PF02277.12 EKE37679.1 - 0.011 14.8 0.2 2.2 7.2 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosyltransferase Sigma54_activat PF00158.21 EKE37679.1 - 0.016 14.7 0.0 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EKE37679.1 - 0.017 14.8 1.3 0.13 11.8 0.9 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EKE37679.1 - 0.026 15.3 0.2 0.046 14.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EKE37679.1 - 0.054 12.9 0.0 0.084 12.3 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EKE37679.1 - 0.077 12.4 0.1 2.5 7.5 0.0 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EKE37679.1 - 0.097 12.1 0.0 2.7 7.4 0.0 2.3 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EKE37679.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EKE37679.1 - 0.14 12.4 4.2 0.23 11.7 2.9 1.3 1 0 0 1 1 1 0 AAA domain RWD PF05773.17 EKE37680.1 - 4.5e-13 49.0 3.6 4.5e-13 49.0 2.5 2.2 2 1 0 2 2 2 1 RWD domain UEV PF05743.8 EKE37680.1 - 0.067 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Adenylsucc_synt PF00709.16 EKE37680.1 - 0.87 8.1 6.0 1.2 7.7 4.0 1.3 1 1 0 1 1 1 0 Adenylosuccinate synthetase TPR_11 PF13414.1 EKE37681.1 - 6.2e-13 48.1 0.6 1.7e-07 30.7 0.1 3.5 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EKE37681.1 - 3e-12 45.4 7.8 0.00017 21.2 0.1 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKE37681.1 - 6e-11 41.4 7.4 0.00062 19.2 0.1 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EKE37681.1 - 4.3e-10 39.3 0.0 0.083 13.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE37681.1 - 3.1e-09 35.9 9.4 0.0078 15.9 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKE37681.1 - 1.8e-08 33.9 0.1 0.00081 19.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKE37681.1 - 5.6e-08 33.0 0.1 0.002 18.4 0.0 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE37681.1 - 9.3e-07 29.3 0.0 0.004 17.8 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE37681.1 - 0.00075 19.3 2.1 0.38 10.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKE37681.1 - 0.0059 16.3 0.3 20 5.2 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EKE37681.1 - 0.017 14.2 1.2 0.054 12.5 0.6 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EKE37681.1 - 0.02 15.0 0.5 0.19 11.8 0.1 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 YfdX PF10938.3 EKE37681.1 - 0.04 13.5 0.2 0.97 9.0 0.0 2.7 3 0 0 3 3 3 0 YfdX protein TPR_10 PF13374.1 EKE37681.1 - 0.07 13.0 1.7 6.6 6.8 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE37681.1 - 0.16 12.4 1.7 21 5.8 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4477 PF14780.1 EKE37682.1 - 0.03 13.7 0.4 0.03 13.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) DUF2419 PF10343.4 EKE37684.1 - 8.4e-66 222.1 0.0 1.4e-65 221.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1688 PF07958.6 EKE37684.1 - 0.024 13.2 0.0 1.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) Glyco_hydro_14 PF01373.12 EKE37685.1 - 8.2e-102 340.9 3.7 1e-101 340.6 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.14 EKE37685.1 - 0.015 14.6 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Allexi_40kDa PF05549.6 EKE37686.1 - 0.024 13.9 7.0 0.03 13.6 4.9 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Usp PF00582.21 EKE37686.1 - 0.18 12.0 10.8 1.7 8.8 7.5 2.1 1 1 0 1 1 1 0 Universal stress protein family SAPS PF04499.10 EKE37686.1 - 0.36 9.3 17.8 0.44 9.1 12.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIIC_delta PF12657.2 EKE37686.1 - 2.5 7.7 5.4 7.2 6.2 3.6 1.9 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Atrophin-1 PF03154.10 EKE37687.1 - 7.2 4.6 9.1 8.9 4.3 6.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family PTH2 PF01981.11 EKE37688.1 - 6.5e-46 154.7 0.2 8.7e-46 154.3 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Phytochelatin PF05023.9 EKE37688.1 - 0.0019 17.1 0.1 0.0024 16.8 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Rsm22 PF09243.5 EKE37688.1 - 0.0023 17.0 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Adenine_glyco PF03352.8 EKE37688.1 - 0.014 14.9 0.1 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 Methyladenine glycosylase DUF268 PF03269.9 EKE37688.1 - 0.083 12.4 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 Pkinase_Tyr PF07714.12 EKE37689.1 - 2.5e-29 102.1 0.1 4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37689.1 - 2.1e-26 92.6 0.7 3.6e-26 91.8 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain FixG_C PF11614.3 EKE37689.1 - 0.00038 20.5 0.8 0.0008 19.5 0.5 1.5 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Kinase-like PF14531.1 EKE37689.1 - 0.0085 15.0 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF2276 PF10040.4 EKE37689.1 - 0.13 12.4 0.0 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2276) NUDIX PF00293.23 EKE37690.1 - 1e-17 64.0 0.0 1.6e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 EKE37690.1 - 1.3e-08 34.5 0.8 8.9e-08 31.9 0.1 2.3 2 0 0 2 2 2 1 Dcp2, box A domain RhoGEF PF00621.15 EKE37691.1 - 5.2e-09 36.2 1.0 5.2e-09 36.2 0.7 4.1 3 0 0 3 3 3 1 RhoGEF domain RhoGAP PF00620.22 EKE37692.1 - 1.7e-28 99.1 0.0 3.9e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain DNA_pol_viral_N PF00242.12 EKE37692.1 - 0.2 10.6 7.6 0.29 10.1 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain 14-3-3 PF00244.15 EKE37693.1 - 1.8e-108 361.0 11.0 2e-108 360.9 7.6 1.0 1 0 0 1 1 1 1 14-3-3 protein ALIX_LYPXL_bnd PF13949.1 EKE37693.1 - 0.003 16.5 1.8 0.003 16.5 1.2 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV TPR_12 PF13424.1 EKE37693.1 - 0.0031 17.4 2.4 0.08 12.8 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Act-Frag_cataly PF09192.5 EKE37693.1 - 0.0082 15.1 0.3 0.013 14.4 0.2 1.2 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic FlaF PF07309.6 EKE37693.1 - 0.026 14.3 0.7 0.095 12.5 0.0 2.2 2 1 0 2 2 2 0 Flagellar protein FlaF DUF837 PF05769.6 EKE37693.1 - 0.097 12.2 5.6 0.67 9.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF885 PF05960.6 EKE37693.1 - 0.35 9.9 4.4 0.45 9.6 1.9 1.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF885) OmpH PF03938.9 EKE37693.1 - 1.1 9.1 5.8 3.3 7.6 4.0 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_8 PF13181.1 EKE37693.1 - 3.6 7.5 11.4 6.9 6.7 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Hexokinase_1 PF00349.16 EKE37694.1 - 2.3e-08 33.6 0.2 2.4e-08 33.5 0.1 1.0 1 0 0 1 1 1 1 Hexokinase RhoGEF PF00621.15 EKE37695.1 - 1.8e-46 158.2 10.7 1.8e-46 158.2 7.5 2.6 3 0 0 3 3 3 1 RhoGEF domain Mitofilin PF09731.4 EKE37695.1 - 0.015 14.0 6.2 0.023 13.3 4.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mdv1 PF11542.3 EKE37695.1 - 0.041 13.8 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial division protein 1 DUF3110 PF11360.3 EKE37695.1 - 0.081 12.7 1.2 3.6 7.4 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3110) PH PF00169.24 EKE37695.1 - 0.69 10.1 6.8 0.15 12.3 1.0 2.4 2 1 0 2 2 2 0 PH domain DUF727 PF05303.7 EKE37697.1 - 0.065 13.0 0.5 1.9 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF727) Lge1 PF11488.3 EKE37697.1 - 0.073 13.2 0.0 0.073 13.2 0.0 2.2 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 WW PF00397.21 EKE37697.1 - 0.31 10.9 1.0 45 4.0 0.0 3.1 3 0 0 3 3 3 0 WW domain Bax1-I PF01027.15 EKE37698.1 - 6.9e-10 38.8 33.5 8.5e-10 38.5 23.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ras PF00071.17 EKE37699.1 - 1e-47 161.5 0.3 1.2e-47 161.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37699.1 - 4.4e-18 65.8 0.1 4e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EKE37699.1 - 6.3e-11 42.0 0.1 5.3e-10 39.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EKE37699.1 - 7e-11 41.6 0.1 8.8e-11 41.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE37699.1 - 9.4e-09 35.2 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE37699.1 - 4.4e-08 32.5 0.1 5.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EKE37699.1 - 7.4e-05 21.9 0.1 0.00015 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKE37699.1 - 0.0027 17.8 0.0 0.004 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EKE37699.1 - 0.0031 17.2 0.1 0.0084 15.8 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EKE37699.1 - 0.0032 16.9 0.3 0.32 10.4 0.2 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EKE37699.1 - 0.0039 16.8 0.6 0.0083 15.7 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKE37699.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.13 EKE37699.1 - 0.0048 15.9 0.2 0.0072 15.3 0.1 1.3 1 0 0 1 1 1 1 Septin AAA_10 PF12846.2 EKE37699.1 - 0.0054 16.2 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EKE37699.1 - 0.0056 16.4 0.0 0.008 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AIG1 PF04548.11 EKE37699.1 - 0.0098 15.0 0.1 0.019 14.0 0.1 1.5 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EKE37699.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EKE37699.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.13 EKE37699.1 - 0.014 14.7 0.0 0.55 9.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EKE37699.1 - 0.014 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EKE37699.1 - 0.02 15.0 0.1 0.046 13.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.12 EKE37699.1 - 0.031 13.8 0.7 3.9 6.9 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.4 EKE37699.1 - 0.032 13.1 0.3 0.069 12.0 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 EKE37699.1 - 0.048 13.3 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EKE37699.1 - 0.049 13.9 0.1 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EKE37699.1 - 0.058 13.0 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase MCM PF00493.18 EKE37699.1 - 0.094 11.4 0.1 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family RasGEF PF00617.14 EKE37700.1 - 8.8e-21 74.4 1.8 2.2e-20 73.2 1.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE37700.1 - 0.012 15.6 0.4 0.061 13.4 0.0 2.4 2 0 0 2 2 2 0 RasGEF N-terminal motif Med9 PF07544.8 EKE37701.1 - 0.065 12.9 1.8 13 5.6 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 YscJ_FliF_C PF08345.6 EKE37701.1 - 0.071 13.0 2.0 0.067 13.1 0.6 1.5 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal eIF-1a PF01176.14 EKE37701.1 - 0.15 11.4 2.1 0.34 10.3 1.1 1.9 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 ubiquitin PF00240.18 EKE37701.1 - 0.4 10.1 4.4 8.5 5.8 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin family GA PF01468.12 EKE37701.1 - 0.46 10.6 7.9 12 6.1 0.1 3.6 3 1 0 3 3 3 0 GA module DUF1667 PF07892.6 EKE37703.1 - 0.19 11.4 2.4 2.3 7.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1667) ERF PF04404.7 EKE37703.1 - 0.59 9.6 7.3 0.19 11.2 1.6 2.2 1 1 1 2 2 2 0 ERF superfamily Beach PF02138.13 EKE37704.1 - 1e-104 349.7 0.1 4.6e-104 347.6 0.1 2.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EKE37704.1 - 7.7e-11 41.7 0.0 7.7e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EKE37704.1 - 1.1e-07 32.2 0.0 4.7e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EKE37704.1 - 6.2e-07 29.0 5.0 0.032 14.1 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Histone PF00125.19 EKE37705.1 - 1.7e-28 98.5 0.4 1.7e-28 98.5 0.3 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EKE37705.1 - 1.3e-05 25.2 0.1 7.2e-05 22.9 0.0 1.9 2 1 0 2 2 2 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EKE37705.1 - 0.017 15.1 0.1 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EKE37705.1 - 0.36 10.0 7.3 2.3 7.3 5.1 1.9 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T SKG6 PF08693.5 EKE37706.1 - 0.0002 20.6 5.3 0.0002 20.6 3.7 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain OppC_N PF12911.2 EKE37706.1 - 0.00031 20.0 1.1 0.096 12.0 0.6 2.2 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Rax2 PF12768.2 EKE37706.1 - 0.00051 19.3 0.5 0.00057 19.1 0.4 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mid2 PF04478.7 EKE37706.1 - 0.00061 19.2 3.0 0.0012 18.2 2.1 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 EKE37706.1 - 0.00099 19.4 1.2 0.45 10.9 0.7 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.1 EKE37706.1 - 0.0055 16.7 1.5 0.0068 16.4 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) EpsG PF14897.1 EKE37706.1 - 0.0079 15.1 2.5 0.0085 15.0 1.7 1.0 1 0 0 1 1 1 1 EpsG family DUF4448 PF14610.1 EKE37706.1 - 0.01 15.3 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF997 PF06196.7 EKE37706.1 - 0.018 14.5 1.8 0.038 13.4 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF997) P12 PF12669.2 EKE37706.1 - 0.027 14.6 0.4 1.4 9.2 0.8 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family TMEM154 PF15102.1 EKE37706.1 - 0.031 14.0 1.5 0.049 13.3 0.1 1.8 1 1 1 2 2 2 0 TMEM154 protein family DUF4514 PF14986.1 EKE37706.1 - 0.037 13.8 1.8 0.045 13.5 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4514) DUF1517 PF07466.6 EKE37706.1 - 0.053 12.5 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF4293 PF14126.1 EKE37706.1 - 0.053 13.4 0.5 0.071 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) zf-DHHC PF01529.15 EKE37706.1 - 0.055 12.8 0.5 0.063 12.6 0.3 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2417 PF10329.4 EKE37706.1 - 0.057 12.8 0.1 0.064 12.6 0.1 1.2 1 1 0 1 1 1 0 Region of unknown function (DUF2417) DUF912 PF06024.7 EKE37706.1 - 0.065 13.2 1.9 0.12 12.4 1.3 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1191 PF06697.7 EKE37706.1 - 0.082 11.7 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CbiN PF02553.10 EKE37706.1 - 0.093 12.7 0.3 1.8 8.6 0.3 2.1 2 0 0 2 2 2 0 Cobalt transport protein component CbiN DUF3899 PF13038.1 EKE37706.1 - 0.11 12.7 1.6 0.29 11.3 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) AJAP1_PANP_C PF15298.1 EKE37706.1 - 0.11 12.4 0.1 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3671 PF12420.3 EKE37706.1 - 0.11 12.4 1.5 0.15 12.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function GRP PF07172.6 EKE37706.1 - 0.14 12.6 0.1 8.5 6.9 0.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family LRRC37AB_C PF14914.1 EKE37706.1 - 0.2 11.0 2.5 0.1 12.0 0.6 1.4 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain stn_TNFRSF12A PF12191.3 EKE37706.1 - 0.23 11.5 1.3 0.42 10.6 0.6 1.6 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Oxidored_q3 PF00499.15 EKE37706.1 - 0.23 11.2 4.5 0.93 9.2 3.2 1.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Viral_Beta_CD PF04530.7 EKE37706.1 - 0.31 11.2 1.4 0.48 10.5 0.9 1.4 1 1 0 1 1 1 0 Viral Beta C/D like family Herpes_UL45 PF05473.7 EKE37706.1 - 1.2 8.5 3.4 1.7 8.0 2.2 1.5 1 1 0 1 1 1 0 UL45 protein DUF4363 PF14276.1 EKE37706.1 - 1.2 8.7 4.9 12 5.6 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) MLANA PF14991.1 EKE37706.1 - 1.4 8.9 3.7 18 5.3 1.9 2.1 1 1 1 2 2 2 0 Protein melan-A DUF3149 PF11346.3 EKE37706.1 - 1.7 8.2 7.3 2.2 7.9 3.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3149) DUF2500 PF10694.4 EKE37706.1 - 1.9 8.5 4.5 4.7 7.2 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2500) ETRAMP PF09716.5 EKE37706.1 - 2 8.4 5.9 10 6.1 4.1 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.1 EKE37706.1 - 2.1 8.4 9.2 1.5 8.8 2.5 2.1 1 1 1 2 2 2 0 Sigma factor regulator N-terminal Synaptobrevin PF00957.16 EKE37706.1 - 2.2 7.9 5.6 0.47 10.0 1.2 2.0 1 1 1 2 2 2 0 Synaptobrevin Orthoreo_P10 PF07204.6 EKE37706.1 - 2.2 8.0 6.3 0.38 10.5 0.3 2.0 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 Tetraspannin PF00335.15 EKE37706.1 - 2.3 7.4 7.2 6.8 5.9 0.1 2.0 1 1 1 2 2 2 0 Tetraspanin family Baculo_11_kDa PF06143.6 EKE37706.1 - 5.8 6.3 8.0 0.45 9.9 1.4 1.9 1 1 1 2 2 2 0 Baculovirus 11 kDa family Protocadherin PF08374.6 EKE37706.1 - 7.1 6.1 6.5 0.78 9.3 1.0 1.7 1 1 1 2 2 2 0 Protocadherin ODV-E18 PF10717.4 EKE37706.1 - 7.5 6.0 13.0 1.8 8.0 0.8 2.4 1 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF1510 PF07423.6 EKE37706.1 - 9.6 5.4 6.2 15 4.8 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Nucleoporin2 PF04096.9 EKE37707.1 - 1.6e-25 89.5 0.2 4e-25 88.2 0.2 1.7 1 1 0 1 1 1 1 Nucleoporin autopeptidase SUI1 PF01253.17 EKE37708.1 - 2.2e-19 69.0 0.0 2.8e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mut7-C PF01927.11 EKE37708.1 - 0.015 15.3 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain SRP9-21 PF05486.7 EKE37709.1 - 2.2e-09 36.9 1.4 2.4e-09 36.7 1.0 1.0 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF2483 PF10656.4 EKE37709.1 - 0.0082 16.2 1.8 0.0096 15.9 1.2 1.2 1 0 0 1 1 1 1 Hypothetical protein of unknown function (DUF2483) DUF3608 PF12257.3 EKE37710.1 - 0.017 14.0 0.4 0.017 14.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3608) V_ATPase_I PF01496.14 EKE37710.1 - 7.1 4.3 19.9 9.3 3.9 13.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS5 PF14817.1 EKE37710.1 - 9.1 4.6 20.3 0.63 8.5 10.3 1.6 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 5 NAAA-beta PF15508.1 EKE37711.1 - 0.073 13.4 0.2 27 5.1 0.0 2.9 2 1 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Baculo_p24 PF05073.7 EKE37711.1 - 0.11 11.9 3.2 0.59 9.6 0.1 2.6 2 1 0 2 2 2 0 Baculovirus P24 capsid protein RNase_P_p30 PF01876.11 EKE37712.1 - 2.8e-30 104.5 1.2 3.8e-30 104.1 0.8 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Med24_N PF11277.3 EKE37712.1 - 0.082 10.4 0.0 0.097 10.1 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal HMG_box PF00505.14 EKE37713.1 - 3.6e-20 71.9 7.8 3.6e-20 71.9 5.4 5.1 3 1 2 5 5 5 1 HMG (high mobility group) box LisH PF08513.6 EKE37713.1 - 1e-05 25.1 0.1 1.8e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 LisH zf-UBR PF02207.15 EKE37714.1 - 0.03 14.0 17.5 0.053 13.2 11.1 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF1453 PF07301.6 EKE37714.1 - 0.41 10.5 7.4 1.1 9.1 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) zf-B_box PF00643.19 EKE37714.1 - 0.42 10.5 13.5 0.19 11.6 7.1 2.3 2 0 0 2 2 2 0 B-box zinc finger KOG2701 PF09762.4 EKE37715.1 - 1.7e-41 142.3 0.0 1.7e-41 142.3 0.0 3.7 2 2 2 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) DUF2404 PF10296.4 EKE37715.1 - 0.076 13.1 1.5 0.22 11.6 0.0 2.6 3 0 0 3 3 3 0 Putative integral membrane protein conserved region (DUF2404) RhoGEF PF00621.15 EKE37716.1 - 7.8e-32 110.5 14.7 7.8e-32 110.5 10.2 2.5 3 0 0 3 3 3 1 RhoGEF domain ArfGap PF01412.13 EKE37716.1 - 1.1e-12 47.7 0.0 5.2e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CH PF00307.26 EKE37716.1 - 1.3e-09 38.0 0.5 5.6e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain PH PF00169.24 EKE37716.1 - 3.2e-07 30.4 0.0 0.00091 19.4 0.0 3.1 2 0 0 2 2 2 2 PH domain IQ PF00612.22 EKE37716.1 - 0.02 14.5 0.1 0.058 13.0 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif SAPS PF04499.10 EKE37717.1 - 0.069 11.7 3.0 0.086 11.4 2.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SAPS PF04499.10 EKE37718.1 - 0.026 13.1 0.9 0.03 12.9 0.4 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein SMK-1 PF04802.10 EKE37718.1 - 0.076 12.5 6.9 0.38 10.2 0.6 2.2 2 0 0 2 2 2 0 Component of IIS longevity pathway SMK-1 PAP2_3 PF14378.1 EKE37718.1 - 0.11 11.9 0.6 0.18 11.3 0.4 1.3 1 0 0 1 1 1 0 PAP2 superfamily DUF3816 PF12822.2 EKE37718.1 - 5.6 6.8 10.5 14 5.5 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) PP2C PF00481.16 EKE37720.1 - 1.8e-37 129.1 0.6 4.4e-37 127.8 0.4 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE37720.1 - 4.4e-07 29.5 0.0 1.6e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE37720.1 - 0.00059 19.5 0.1 0.011 15.5 0.1 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) MAGP PF05507.6 EKE37720.1 - 0.0047 16.7 1.3 0.0064 16.2 0.3 1.6 2 0 0 2 2 2 1 Microfibril-associated glycoprotein (MAGP) Prefoldin PF02996.12 EKE37721.1 - 7.1e-14 51.4 1.9 7.1e-14 51.4 1.3 1.7 1 1 1 2 2 2 1 Prefoldin subunit HTH_1 PF00126.22 EKE37721.1 - 0.0074 16.0 0.3 0.013 15.2 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family ATP-synt_E PF05680.7 EKE37721.1 - 0.068 13.1 1.6 0.073 13.0 0.2 1.8 2 0 0 2 2 2 0 ATP synthase E chain Gar1 PF04410.9 EKE37722.1 - 7e-16 58.0 6.7 1.4e-15 57.0 4.6 1.5 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region GUCT PF08152.7 EKE37723.1 - 0.38 10.7 4.0 0.45 10.5 1.6 1.8 1 1 1 2 2 2 0 GUCT (NUC152) domain TEX19 PF15553.1 EKE37723.1 - 0.59 9.9 5.5 0.76 9.6 3.8 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Pilus_CpaD PF09476.5 EKE37723.1 - 1.1 8.6 4.2 1.4 8.3 2.9 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF448 PF04296.8 EKE37723.1 - 1.5 8.5 5.6 0.27 10.8 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF448) Astro_capsid PF03115.9 EKE37723.1 - 1.5 7.0 10.4 1.5 6.9 7.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor AstA PF04958.7 EKE37724.1 - 0.1 11.0 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF1632 PF07857.7 EKE37725.1 - 5.5e-60 202.7 5.1 5.5e-60 202.7 3.5 2.4 2 1 0 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 EKE37725.1 - 2.6e-10 39.8 19.4 2e-08 33.6 1.3 2.8 3 0 0 3 3 3 2 Sugar transport protein ALG3 PF05208.8 EKE37725.1 - 0.00081 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 ALG3 protein Trypan_PARP PF05887.6 EKE37725.1 - 0.19 11.5 7.4 0.38 10.5 5.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TRAP_alpha PF03896.11 EKE37725.1 - 0.35 9.8 1.8 0.54 9.1 1.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FUSC-like PF12805.2 EKE37725.1 - 6.5 5.5 5.5 0.57 9.0 0.5 1.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Pkinase_Tyr PF07714.12 EKE37727.1 - 1.6e-48 165.0 0.0 3.4e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37727.1 - 9.3e-44 149.5 0.0 2.5e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Baculo_11_kDa PF06143.6 EKE37727.1 - 0.39 10.0 3.6 0.38 10.1 1.1 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family PARG_cat PF05028.9 EKE37729.1 - 3.7e-58 197.3 0.0 4.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) SUR7 PF06687.7 EKE37730.1 - 0.00012 21.7 1.0 0.00013 21.6 0.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family COX15-CtaA PF02628.10 EKE37730.1 - 0.0022 16.9 0.0 0.0023 16.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PalH PF08733.5 EKE37730.1 - 0.011 14.6 0.8 0.013 14.4 0.6 1.1 1 0 0 1 1 1 0 PalH/RIM21 MARVEL PF01284.18 EKE37730.1 - 0.012 15.4 1.2 0.017 14.9 0.8 1.4 1 0 0 1 1 1 0 Membrane-associating domain DUF2207 PF09972.4 EKE37730.1 - 0.019 13.5 0.4 0.022 13.3 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.13 EKE37730.1 - 0.042 13.6 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A MgtE PF01769.11 EKE37730.1 - 0.047 13.9 0.8 0.056 13.7 0.6 1.1 1 0 0 1 1 1 0 Divalent cation transporter DUF872 PF05915.7 EKE37730.1 - 0.091 12.6 0.6 0.19 11.6 0.2 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF4064 PF13273.1 EKE37730.1 - 0.092 12.8 6.0 0.023 14.7 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Pox_A14 PF05767.7 EKE37730.1 - 6.6 6.7 7.2 20 5.2 5.0 1.7 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 RNA_pol_Rpb1_5 PF04998.12 EKE37731.1 - 0.0082 15.4 1.3 0.0099 15.1 0.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 HALZ PF02183.13 EKE37733.1 - 0.11 12.2 20.5 0.55 10.0 0.3 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper IncA PF04156.9 EKE37733.1 - 2.1 7.9 35.5 2.4 7.7 9.7 2.8 2 1 0 2 2 2 0 IncA protein Erythrovirus_X PF06795.6 EKE37734.1 - 0.036 14.0 1.7 1.5 8.8 0.1 2.9 2 1 1 3 3 3 0 Erythrovirus X protein DUF1284 PF06935.6 EKE37734.1 - 0.12 12.5 0.7 0.22 11.7 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Rotamase PF00639.16 EKE37735.1 - 0.072 13.8 1.1 11 6.8 0.0 3.3 3 0 0 3 3 3 0 PPIC-type PPIASE domain Cob_adeno_trans PF01923.13 EKE37735.1 - 0.29 10.8 3.1 2.4 7.9 0.1 2.8 3 0 0 3 3 3 0 Cobalamin adenosyltransferase Pkinase_Tyr PF07714.12 EKE37736.1 - 1.2e-46 158.9 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37736.1 - 2.5e-44 151.4 0.0 3e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.6 EKE37736.1 - 0.011 14.5 0.1 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4128 PF13554.1 EKE37736.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Kinase-like PF14531.1 EKE37736.1 - 0.074 12.0 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EKE37736.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.17 EKE37737.1 - 6.4e-47 158.9 2.3 8.8e-47 158.4 1.6 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37737.1 - 1.4e-19 70.7 0.2 2.2e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE37737.1 - 7.6e-12 44.8 0.1 1.2e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE37737.1 - 1e-07 31.3 0.2 1.3e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE37737.1 - 1.3e-06 27.7 0.2 1.3e-06 27.7 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE37737.1 - 0.00016 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE37737.1 - 0.00035 20.0 0.5 0.0028 17.0 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PqiA PF04403.8 EKE37738.1 - 6.7e-11 42.0 6.9 6.7e-11 42.0 4.8 1.8 2 0 0 2 2 2 1 Paraquat-inducible protein A DUF1510 PF07423.6 EKE37738.1 - 0.00038 19.8 8.7 0.00054 19.3 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EKE37738.1 - 0.001 16.9 0.3 0.0012 16.7 0.2 1.0 1 0 0 1 1 1 1 Ycf1 Nucleoside_tran PF01733.13 EKE37738.1 - 0.036 13.2 3.9 0.25 10.4 0.1 2.3 2 0 0 2 2 2 0 Nucleoside transporter TRAP_alpha PF03896.11 EKE37738.1 - 0.056 12.4 3.6 0.099 11.6 2.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.17 EKE37738.1 - 0.059 12.3 3.1 0.1 11.5 2.2 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1449 PF07290.6 EKE37738.1 - 0.063 12.6 0.3 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) Neur_chan_memb PF02932.11 EKE37738.1 - 0.16 11.8 0.2 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.7 EKE37738.1 - 2.3 7.2 16.5 2.9 6.9 11.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.8 EKE37738.1 - 9.5 4.8 17.1 12 4.5 11.9 1.1 1 0 0 1 1 1 0 Paf1 PqiA PF04403.8 EKE37739.1 - 7.2e-11 41.9 7.2 7.2e-11 41.9 5.0 2.2 2 0 0 2 2 2 1 Paraquat-inducible protein A Rer1 PF03248.8 EKE37739.1 - 0.001 18.7 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Rer1 family PYC_OADA PF02436.13 EKE37740.1 - 5.8e-52 175.9 0.0 1.1e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Carboxyl_trans PF01039.17 EKE37740.1 - 8.7e-27 93.6 0.5 1.9e-26 92.4 0.2 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain HMGL-like PF00682.14 EKE37740.1 - 9.1e-22 77.8 0.0 1.9e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ACCA PF03255.9 EKE37740.1 - 9.3e-20 70.6 0.1 4.4e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Biotin_lipoyl PF00364.17 EKE37740.1 - 2.1e-15 56.0 2.6 6e-15 54.6 1.8 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EKE37740.1 - 8.4e-07 28.5 0.2 0.0017 17.9 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.1 EKE37740.1 - 0.0029 17.2 0.3 0.007 16.0 0.2 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 EKE37740.1 - 0.12 12.0 0.4 0.33 10.6 0.3 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF3437 PF11919.3 EKE37741.1 - 1e-07 31.5 0.1 3.5e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) VPS9 PF02204.13 EKE37742.1 - 7.3e-20 70.9 0.1 1.6e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SSrecog PF03531.9 EKE37743.1 - 1.1e-41 142.6 0.9 4.7e-41 140.5 0.3 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EKE37743.1 - 1.1e-19 70.2 1.4 3.9e-19 68.4 0.3 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like NOA36 PF06524.7 EKE37743.1 - 0.011 15.0 2.8 0.019 14.2 1.9 1.5 1 0 0 1 1 1 0 NOA36 protein GH97_C PF14509.1 EKE37743.1 - 0.57 10.3 0.1 0.57 10.3 0.0 2.4 3 0 0 3 3 3 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation CobT PF06213.7 EKE37743.1 - 5 6.1 14.8 10 5.1 10.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 EKE37744.1 - 0.0038 16.6 0.1 0.0045 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4435 PF14491.1 EKE37744.1 - 0.019 14.7 1.3 0.024 14.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) ExbD PF02472.11 EKE37744.1 - 0.14 12.1 1.8 0.19 11.7 1.2 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR FtsL PF04999.8 EKE37744.1 - 0.32 10.7 2.9 17 5.1 1.1 2.4 2 1 0 2 2 2 0 Cell division protein FtsL DUF4163 PF13739.1 EKE37744.1 - 1.2 9.9 9.5 0.38 11.5 4.6 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) DUF4208 PF13907.1 EKE37747.1 - 0.18 12.0 2.7 0.18 12.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Pkinase PF00069.20 EKE37748.1 - 1.3e-50 172.0 0.0 2.9e-50 170.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37748.1 - 1.6e-17 63.4 0.0 3.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase BBS2_N PF14781.1 EKE37748.1 - 0.0027 17.3 0.1 0.014 15.0 0.0 2.0 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal RIO1 PF01163.17 EKE37748.1 - 0.0061 15.9 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EKE37748.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RhoGEF PF00621.15 EKE37749.1 - 1e-43 149.2 7.1 1e-43 149.2 4.9 2.5 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 EKE37749.1 - 0.00072 19.7 0.8 0.00072 19.7 0.6 2.2 2 1 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.12 EKE37750.1 - 5.6e-53 179.6 0.0 8.7e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37750.1 - 2.3e-48 164.6 0.7 2.8e-48 164.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain RNA_pol_Rpb1_2 PF00623.15 EKE37750.1 - 0.076 12.9 0.6 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 2 Kdo PF06293.9 EKE37750.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family mRNA_cap_enzyme PF01331.14 EKE37752.1 - 4.7e-28 98.2 1.9 4.7e-28 98.2 1.3 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_triPase PF02940.10 EKE37752.1 - 9.8e-10 38.5 6.9 5.1e-09 36.1 4.8 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain DNA_ligase_A_M PF01068.16 EKE37752.1 - 2e-09 37.1 1.5 0.00018 20.9 0.0 2.6 1 1 1 2 2 2 2 ATP dependent DNA ligase domain mRNA_cap_C PF03919.10 EKE37752.1 - 1.2e-06 28.7 0.2 1.2e-06 28.7 0.1 2.9 3 0 0 3 3 3 1 mRNA capping enzyme, C-terminal domain DUF4507 PF14964.1 EKE37754.1 - 0.041 12.6 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) DASH_Dad2 PF08654.5 EKE37754.1 - 0.047 13.6 1.4 0.18 11.8 1.0 2.0 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF2277 PF10041.4 EKE37754.1 - 0.05 13.5 0.9 0.26 11.2 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) EcsC PF12787.2 EKE37754.1 - 0.066 12.5 1.2 0.71 9.2 0.1 2.7 3 0 0 3 3 3 0 EcsC protein family DUF948 PF06103.6 EKE37754.1 - 0.37 10.6 7.5 0.17 11.7 0.7 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) RuvA_N PF01330.16 EKE37755.1 - 0.019 14.7 0.5 0.065 13.0 0.1 2.2 2 0 0 2 2 2 0 RuvA N terminal domain Profilin PF00235.14 EKE37756.1 - 6.8e-25 87.5 0.5 7.7e-25 87.3 0.4 1.0 1 0 0 1 1 1 1 Profilin Glyco_hydro_18 PF00704.23 EKE37757.1 - 8.1e-101 337.8 14.4 9.8e-101 337.6 10.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Corona_6B_7B PF03262.8 EKE37759.1 - 0.031 13.5 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Coronavirus 6B/7B protein Atrophin-1 PF03154.10 EKE37759.1 - 0.14 10.2 5.7 0.16 10.0 4.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family DBR1 PF05011.8 EKE37759.1 - 0.35 10.7 9.0 0.32 10.8 3.0 2.0 1 1 1 2 2 2 0 Lariat debranching enzyme, C-terminal domain SPT16 PF08644.6 EKE37760.1 - 1.9e-27 95.9 0.5 1.9e-27 95.9 0.3 3.0 2 1 1 3 3 3 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 EKE37760.1 - 1.9e-20 72.6 0.2 7.1e-20 70.7 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like HD PF01966.17 EKE37761.1 - 4.6e-09 36.3 0.0 6.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 HD domain Autophagy_act_C PF03987.10 EKE37761.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain DUF3447 PF11929.3 EKE37761.1 - 0.19 11.5 4.4 0.17 11.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Ras PF00071.17 EKE37762.1 - 2.4e-21 75.8 0.0 3.1e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37762.1 - 0.0013 19.1 0.0 0.0033 17.9 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein RE_Eco47II PF09553.5 EKE37762.1 - 0.055 12.5 0.2 0.14 11.2 0.1 1.6 1 1 0 1 1 1 0 Eco47II restriction endonuclease RE_NgoBV PF09564.5 EKE37762.1 - 0.11 11.6 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 NgoBV restriction endonuclease PNTB PF02233.11 EKE37763.1 - 2.7e-76 257.2 5.0 3.1e-76 257.0 3.4 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit Dynamin_N PF00350.18 EKE37764.1 - 7.1e-11 42.2 0.0 4.1e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EKE37764.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKE37764.1 - 0.029 14.8 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 EKE37764.1 - 0.03 14.0 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EKE37764.1 - 0.032 14.1 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EKE37764.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Peptidase_S74 PF13884.1 EKE37765.1 - 1.6e-13 50.5 0.0 5e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Chaperone of endosialidase RasGAP PF00616.14 EKE37766.1 - 1.5e-31 109.6 0.7 2.7e-31 108.7 0.5 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase SH3_1 PF00018.23 EKE37767.1 - 2.9e-14 52.1 0.1 5.6e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EKE37767.1 - 4.3e-13 48.5 0.0 1.1e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EKE37767.1 - 7e-13 47.9 0.0 1.2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain IL8 PF00048.15 EKE37767.1 - 0.033 14.1 0.5 0.1 12.5 0.3 1.8 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like Sec5 PF15469.1 EKE37769.1 - 2.3e-14 53.5 9.3 2.3e-14 53.5 6.5 4.2 4 2 1 5 5 5 1 Exocyst complex component Sec5 DnaJ PF00226.26 EKE37770.1 - 1.1e-20 73.1 0.8 1.7e-20 72.5 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EKE37771.1 - 1.2e-06 28.0 1.0 3.8e-06 26.4 0.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAN_2 PF08276.6 EKE37771.1 - 0.042 13.6 2.9 0.08 12.7 2.0 1.4 1 0 0 1 1 1 0 PAN-like domain Piwi PF02171.12 EKE37772.1 - 7.8e-53 179.3 3.6 1.1e-52 178.8 2.5 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EKE37772.1 - 8.4e-23 80.1 1.5 2.3e-22 78.7 1.0 1.7 1 0 0 1 1 1 1 PAZ domain DUF766 PF05571.7 EKE37773.1 - 0.017 14.3 0.3 0.022 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF766) TIL PF01826.12 EKE37773.1 - 2.6 8.2 9.9 4.5 7.4 6.9 1.4 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain GPAT_N PF14829.1 EKE37774.1 - 0.0014 18.2 0.1 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal Bactofilin PF04519.8 EKE37775.1 - 0.057 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Ndc80_HEC PF03801.8 EKE37776.1 - 1.7e-08 34.0 0.2 1.7e-08 34.0 0.1 2.6 2 2 0 2 2 2 1 HEC/Ndc80p family Myb_DNA-binding PF00249.26 EKE37777.1 - 1.8e-11 43.8 0.6 2.6e-11 43.3 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE37777.1 - 0.023 14.7 0.2 0.044 13.8 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3275 PF11679.3 EKE37777.1 - 0.04 13.5 0.2 0.063 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) IPK PF03770.11 EKE37777.1 - 0.087 12.4 1.7 0.11 12.0 1.2 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase RRM_1 PF00076.17 EKE37778.1 - 2.9e-13 49.2 0.0 3.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37778.1 - 3.7e-09 36.4 0.0 4.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE37778.1 - 1.4e-07 31.2 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKE37778.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 0 RNA binding motif SET_assoc PF11767.3 EKE37778.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Sua5_yciO_yrdC PF01300.13 EKE37778.1 - 0.029 13.6 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Telomere recombination Limkain-b1 PF11608.3 EKE37778.1 - 0.057 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.1 EKE37778.1 - 0.06 13.1 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF2096 PF09869.4 EKE37779.1 - 0.036 13.9 3.8 4.7 7.0 0.9 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) DUF4162 PF13732.1 EKE37779.1 - 0.15 12.6 5.0 0.35 11.4 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) DUF1033 PF06279.6 EKE37779.1 - 1.3 8.8 5.7 2.5 7.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1033) RabGAP-TBC PF00566.13 EKE37780.1 - 2.8e-29 102.1 0.8 3.9e-29 101.6 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lys PF00062.15 EKE37780.1 - 0.0091 15.9 1.0 0.019 14.9 0.2 1.8 2 0 0 2 2 2 1 C-type lysozyme/alpha-lactalbumin family FMN_red PF03358.10 EKE37781.1 - 1.1e-22 80.1 0.0 1.3e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EKE37781.1 - 8.3e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EKE37781.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin Pkinase PF00069.20 EKE37782.1 - 1.6e-32 112.7 0.4 3.4e-32 111.6 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37782.1 - 1.3e-30 106.3 0.1 2e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RsgI_N PF12791.2 EKE37782.1 - 0.028 14.0 0.1 0.071 12.7 0.0 1.7 1 0 0 1 1 1 0 Anti-sigma factor N-terminus zf-C4H2 PF10146.4 EKE37784.1 - 0.073 13.0 1.3 0.078 12.9 0.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein PQQ_2 PF13360.1 EKE37785.1 - 0.022 14.2 0.0 0.053 12.9 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain Sec1 PF00995.18 EKE37786.1 - 6.9e-45 153.7 5.0 9.9e-45 153.2 3.5 1.1 1 0 0 1 1 1 1 Sec1 family E1-E2_ATPase PF00122.15 EKE37787.1 - 3.6e-21 75.2 0.4 8.9e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKE37787.1 - 2.1e-15 57.7 0.1 6.2e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE37787.1 - 1.3e-13 51.5 0.0 3.6e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE37787.1 - 2.6e-08 33.6 0.5 7.3e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_6 PF13344.1 EKE37787.1 - 0.0054 16.5 0.1 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase TIR PF01582.15 EKE37788.1 - 0.022 14.1 0.3 0.048 13.0 0.2 1.7 1 1 0 1 1 1 0 TIR domain RRM_1 PF00076.17 EKE37789.1 - 8.5e-12 44.5 0.0 2.2e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37789.1 - 9.8e-09 35.0 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE37789.1 - 8.1e-08 31.9 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1699 PF08004.6 EKE37789.1 - 0.0059 16.1 1.1 0.014 14.9 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1699) Snurportin1 PF11538.3 EKE37789.1 - 0.084 12.6 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Snurportin1 LMSTEN PF07988.7 EKE37789.1 - 0.94 8.8 8.7 2 7.7 0.2 3.2 1 1 2 3 3 3 0 LMSTEN motif His_Phos_1 PF00300.17 EKE37791.1 - 7.9e-17 61.7 0.4 3.1e-16 59.8 0.0 1.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) ubiquitin PF00240.18 EKE37792.1 - 1.8e-33 113.7 0.5 2e-33 113.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE37792.1 - 7.1e-21 73.6 0.4 7.9e-21 73.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKE37792.1 - 7.8e-06 26.0 0.1 3.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EKE37792.1 - 0.00028 20.5 0.0 0.00032 20.4 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EKE37792.1 - 0.0047 16.7 0.1 0.0092 15.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EKE37792.1 - 0.013 15.5 0.1 0.036 14.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EKE37792.1 - 0.085 12.7 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG eRF1_1 PF03463.10 EKE37792.1 - 0.11 12.0 0.0 2.4 7.7 0.0 2.0 1 1 1 2 2 2 0 eRF1 domain 1 DUF2407 PF10302.4 EKE37792.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain GvpL_GvpF PF06386.6 EKE37793.1 - 0.81 9.2 6.4 1.5 8.3 4.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1664 PF07889.7 EKE37793.1 - 1.4 8.6 7.9 4.2 7.1 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3573 PF12097.3 EKE37793.1 - 7.1 5.1 10.6 0.38 9.2 3.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Sec23_trunk PF04811.10 EKE37794.1 - 7.7e-52 176.0 0.3 1.3e-51 175.3 0.2 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EKE37794.1 - 1.2e-29 101.7 0.2 3.2e-29 100.3 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EKE37794.1 - 9.7e-18 64.4 0.1 1.6e-16 60.5 0.0 2.6 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EKE37794.1 - 6e-06 25.8 0.0 1.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 EKE37794.1 - 3.9e-05 23.1 10.5 0.00013 21.4 7.3 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DSPc PF00782.15 EKE37795.1 - 1e-29 102.7 0.1 1.4e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE37795.1 - 0.0051 16.1 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EKE37795.1 - 0.0055 16.1 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.7 EKE37795.1 - 0.01 14.7 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Myotub-related PF06602.9 EKE37795.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EKE37795.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKE37795.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CorA PF01544.13 EKE37796.1 - 5.8e-22 78.0 11.3 5.8e-22 78.0 7.8 2.4 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein Tox-HNH-HHH PF15637.1 EKE37796.1 - 0.039 13.7 1.5 0.098 12.4 1.0 1.6 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Mitofilin PF09731.4 EKE37796.1 - 1.9 7.0 15.0 2.5 6.6 10.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hexokinase_2 PF03727.11 EKE37797.1 - 3.2e-35 121.5 0.3 7.2e-31 107.2 0.0 2.1 2 0 0 2 2 2 2 Hexokinase NOGCT PF08155.6 EKE37797.1 - 0.024 14.3 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 NOGCT (NUC087) domain zf-RING_2 PF13639.1 EKE37801.1 - 1.5e-09 37.5 11.7 3.1e-09 36.5 8.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE37801.1 - 4.8e-09 36.1 12.4 9.6e-09 35.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE37801.1 - 4.5e-08 32.6 7.8 7.4e-08 31.9 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE37801.1 - 6.1e-08 32.1 12.2 6.1e-08 32.1 8.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE37801.1 - 1.1e-05 25.1 9.9 1.7e-05 24.5 6.2 1.8 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EKE37801.1 - 2.5e-05 24.2 6.1 5.2e-05 23.2 4.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EKE37801.1 - 2.9e-05 23.6 3.9 2.9e-05 23.6 2.7 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EKE37801.1 - 5.8e-05 22.7 15.1 8e-05 22.2 8.9 2.3 2 1 1 3 3 3 1 zinc-RING finger domain WW PF00397.21 EKE37801.1 - 0.019 14.8 1.0 0.058 13.2 0.3 2.1 2 0 0 2 2 2 0 WW domain DZR PF12773.2 EKE37801.1 - 0.12 12.1 7.2 0.6 9.9 5.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-Apc11 PF12861.2 EKE37801.1 - 0.13 12.1 8.4 0.48 10.2 5.6 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.7 EKE37801.1 - 0.13 12.0 5.8 0.28 11.0 4.0 1.6 1 0 0 1 1 1 0 zinc-ribbons DUF1244 PF06844.6 EKE37801.1 - 0.32 10.8 1.6 0.46 10.3 0.2 1.9 3 0 0 3 3 1 0 Protein of unknown function (DUF1244) zf-RING_4 PF14570.1 EKE37801.1 - 1 9.0 12.5 16 5.1 8.8 2.2 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain Sulfotransfer_3 PF13469.1 EKE37803.1 - 2.1e-09 38.4 0.0 5.6e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE37803.1 - 0.0013 18.0 0.4 0.015 14.5 0.0 2.6 2 1 0 2 2 2 1 Sulfotransferase domain Y_phosphatase3 PF13350.1 EKE37804.1 - 9.6e-20 71.4 0.0 1.1e-18 68.0 0.0 2.4 2 1 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EKE37804.1 - 3.6e-07 30.1 0.0 5.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region DUF2404 PF10296.4 EKE37805.1 - 8.2e-08 32.2 0.0 2.3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Ribosomal_L25p PF01386.14 EKE37805.1 - 0.044 13.8 2.1 2.2 8.4 0.2 3.0 2 0 0 2 2 2 0 Ribosomal L25p family BRO1 PF03097.13 EKE37806.1 - 2.2e-62 210.9 13.0 2.2e-62 210.9 9.0 2.3 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EKE37806.1 - 7.1e-26 90.8 14.3 1.3e-24 86.7 9.9 2.8 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Peptidase_C1 PF00112.18 EKE37807.1 - 8.7e-31 107.5 0.6 2.1e-30 106.2 0.4 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE37807.1 - 2.1e-09 37.5 5.5 7.6e-09 35.7 3.8 2.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) G-alpha PF00503.15 EKE37807.1 - 0.013 14.2 0.2 0.021 13.5 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Ras PF00071.17 EKE37808.1 - 1.1e-49 167.9 0.7 1.3e-49 167.7 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37808.1 - 1e-20 74.3 0.1 1.4e-19 70.7 0.1 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE37808.1 - 3.6e-17 62.1 0.4 5.3e-17 61.5 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE37808.1 - 9.1e-07 28.4 0.2 4.5e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE37808.1 - 1.3e-06 27.7 0.1 1.6e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE37808.1 - 1.9e-06 27.8 0.4 6.6e-06 26.0 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE37808.1 - 0.0001 21.5 0.2 0.00039 19.6 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EKE37808.1 - 0.0001 21.5 0.1 0.00041 19.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EKE37808.1 - 0.00018 21.6 0.0 0.00051 20.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKE37808.1 - 0.00069 19.6 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 EKE37808.1 - 0.0018 17.7 0.3 0.02 14.3 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE37808.1 - 0.0058 15.8 0.1 0.036 13.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 G-alpha PF00503.15 EKE37808.1 - 0.013 14.1 2.4 1.1 7.8 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit MCM PF00493.18 EKE37808.1 - 0.03 13.1 0.0 0.061 12.1 0.0 1.5 2 0 0 2 2 2 0 MCM2/3/5 family Septin PF00735.13 EKE37808.1 - 0.032 13.2 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.1 EKE37808.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKE37808.1 - 0.043 13.5 0.0 0.061 13.0 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EKE37808.1 - 0.043 13.7 0.2 0.069 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EKE37808.1 - 0.052 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EKE37808.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EKE37808.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EKE37808.1 - 0.087 12.2 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EKE37808.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EKE37809.1 - 1.1e-15 57.4 0.2 1.3e-15 57.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37809.1 - 5e-09 36.6 0.0 1.1e-08 35.5 0.0 1.5 1 1 1 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EKE37809.1 - 0.0011 19.1 0.0 0.047 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EKE37809.1 - 0.0033 16.6 0.0 0.0044 16.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE37809.1 - 0.0039 16.6 0.1 0.16 11.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE37809.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.5 EKE37809.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Septin PF00735.13 EKE37809.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin Glyco_hydro_108 PF05838.7 EKE37809.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Helicase_C PF00271.26 EKE37810.1 - 1.7e-19 69.4 0.0 4.9e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE37810.1 - 2e-19 69.6 0.0 6.8e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Fer4_2 PF12797.2 EKE37810.1 - 0.058 13.3 1.8 0.22 11.5 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Takusan PF04822.8 EKE37810.1 - 0.64 9.8 12.8 0.033 13.9 2.1 3.6 4 0 0 4 4 4 0 Takusan zf-DHHC PF01529.15 EKE37811.1 - 2.3e-36 124.8 17.1 2.3e-36 124.8 11.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase IncA PF04156.9 EKE37811.1 - 0.33 10.5 0.0 0.33 10.5 0.0 3.4 4 0 0 4 4 4 0 IncA protein Peptidase_A22B PF04258.8 EKE37814.1 - 2.9e-37 128.7 29.4 1.7e-36 126.1 20.4 2.0 1 1 0 1 1 1 1 Signal peptide peptidase Peptidase_S74 PF13884.1 EKE37815.1 - 2e-15 56.6 0.0 5.6e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase DUF1212 PF06738.7 EKE37815.1 - 0.4 10.1 8.6 0.62 9.5 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) WD40 PF00400.27 EKE37816.1 - 9.9e-22 75.9 12.9 1.2e-09 37.7 0.2 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat SH3_1 PF00018.23 EKE37817.1 - 8.8e-11 41.0 0.1 1.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EKE37817.1 - 3.4e-10 39.2 0.0 7.5e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EKE37817.1 - 1.1e-07 31.9 0.3 2.6e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 EKE37817.1 - 3.2e-06 26.6 0.0 8e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EKE37817.1 - 1.6e-05 25.1 1.0 3.6e-05 23.9 0.7 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EKE37817.1 - 0.00011 22.2 0.3 0.00028 20.8 0.2 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_3 PF08239.6 EKE37817.1 - 0.00068 19.7 0.1 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain LAT PF15234.1 EKE37817.1 - 0.13 11.7 14.1 0.13 11.7 8.9 1.7 2 0 0 2 2 2 0 Linker for activation of T-cells PAT1 PF09770.4 EKE37817.1 - 0.6 8.2 12.0 0.78 7.9 8.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EKE37817.1 - 3.9 6.7 19.4 4.8 6.4 13.4 1.1 1 0 0 1 1 1 0 Vta1 like PROL5-SMR PF15621.1 EKE37817.1 - 6.1 7.3 16.4 11 6.4 11.3 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family VID27 PF08553.5 EKE37817.1 - 6.8 4.7 12.7 2.7 6.0 6.7 1.7 2 0 0 2 2 2 0 VID27 cytoplasmic protein MIP PF00230.15 EKE37818.1 - 0.0036 16.7 8.8 0.0082 15.6 6.1 1.6 1 1 0 1 1 1 1 Major intrinsic protein MMPL PF03176.10 EKE37818.1 - 0.46 9.1 1.7 0.66 8.6 1.2 1.2 1 0 0 1 1 1 0 MMPL family DUF2450 PF10475.4 EKE37820.1 - 6.7e-06 25.2 11.1 6.7e-06 25.2 7.7 2.3 1 1 1 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 EKE37820.1 - 0.00081 19.3 2.6 0.028 14.4 0.6 3.0 2 0 0 2 2 2 2 Golgi transport complex subunit 5 LRR_4 PF12799.2 EKE37821.1 - 2.1e-08 33.6 31.8 2.2e-05 23.9 5.4 5.2 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE37821.1 - 0.00064 19.4 25.2 0.0027 17.4 4.7 4.3 3 2 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 EKE37821.1 - 0.045 13.7 26.1 3.3 8.0 0.2 6.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EKE37821.1 - 0.96 9.9 16.9 8.6 7.0 0.0 6.4 6 1 0 6 6 6 0 Leucine rich repeat zf-Nse PF11789.3 EKE37822.1 - 1e-18 66.6 0.5 1e-18 66.6 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EKE37822.1 - 2.4e-09 36.7 0.5 7.3e-09 35.2 0.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EKE37822.1 - 1.2e-06 27.9 1.5 1.3e-06 27.8 0.3 1.6 1 1 1 2 2 2 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 EKE37822.1 - 0.0021 18.0 1.2 0.0036 17.2 0.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE37822.1 - 0.0072 16.1 0.2 0.03 14.1 0.1 2.1 1 1 1 2 2 2 1 Ring finger domain zf-MIZ PF02891.15 EKE37822.1 - 0.01 15.2 0.4 0.02 14.4 0.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EKE37822.1 - 0.018 15.1 0.2 0.046 13.8 0.1 1.8 1 1 1 2 2 2 0 RING-H2 zinc finger K167R PF08065.7 EKE37822.1 - 0.03 14.4 0.2 0.066 13.3 0.1 1.6 1 1 0 1 1 1 0 K167R (NUC007) repeat Use1 PF09753.4 EKE37822.1 - 0.04 13.3 0.7 0.059 12.8 0.5 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Fib_alpha PF08702.5 EKE37822.1 - 0.069 13.2 2.3 0.082 13.0 0.4 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-C3HC4 PF00097.20 EKE37822.1 - 0.15 11.7 0.7 0.49 10.0 0.0 2.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Radical_SAM PF04055.16 EKE37823.1 - 3.9e-11 43.4 0.0 8.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EKE37823.1 - 2.1e-10 40.8 0.3 7.8e-10 39.0 0.0 2.1 2 1 1 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EKE37823.1 - 6.4e-06 26.1 0.5 2e-05 24.6 0.0 2.1 3 0 0 3 3 3 1 4Fe-4S single cluster domain Pkinase PF00069.20 EKE37824.1 - 2e-44 151.6 0.5 2.4e-44 151.4 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37824.1 - 2.1e-42 145.0 0.4 2.3e-42 144.8 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKE37824.1 - 0.00011 21.1 0.5 0.00018 20.4 0.1 1.4 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 EKE37824.1 - 0.016 14.5 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EKE37824.1 - 0.051 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SWIRM PF04433.12 EKE37824.1 - 0.13 12.3 2.0 0.28 11.3 0.4 2.1 2 0 0 2 2 2 0 SWIRM domain TLD PF07534.11 EKE37826.1 - 1.2e-05 25.3 0.1 1.3e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 TLD Sec7 PF01369.15 EKE37828.1 - 2.9e-41 141.2 13.4 2.1e-39 135.1 3.1 3.0 2 0 0 2 2 2 2 Sec7 domain Sec7_N PF12783.2 EKE37828.1 - 1.4e-20 73.3 17.9 1.1e-19 70.4 1.5 4.7 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-HIT PF04438.11 EKE37828.1 - 0.28 10.8 9.1 0.57 9.8 6.3 1.6 1 0 0 1 1 1 0 HIT zinc finger TerB PF05099.8 EKE37828.1 - 0.36 10.5 1.2 0.93 9.2 0.8 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TerB zf-MYND PF01753.13 EKE37828.1 - 6.2 6.7 10.9 13 5.7 7.6 1.5 1 0 0 1 1 1 0 MYND finger Beach PF02138.13 EKE37829.1 - 1.3e-66 224.8 2.0 2.6e-66 223.8 0.6 2.2 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 EKE37829.1 - 0.00081 19.1 0.4 0.0045 16.8 0.3 2.4 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH Topoisom_bac PF01131.15 EKE37830.1 - 1.6e-102 343.3 0.1 2.6e-102 342.6 0.0 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.17 EKE37830.1 - 7.4e-14 51.5 0.0 2.1e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Gp-FAR-1 PF05823.7 EKE37830.1 - 0.0096 15.8 1.1 2.3 8.1 0.0 3.3 3 0 0 3 3 3 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) BRCT PF00533.21 EKE37832.1 - 6.1e-05 23.0 1.3 0.00021 21.3 0.9 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKE37832.1 - 0.034 13.9 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain ParA PF10609.4 EKE37832.1 - 0.3 11.0 2.1 2.1 8.2 0.1 2.8 2 1 1 3 3 3 0 ParA/MinD ATPase like EF-hand_7 PF13499.1 EKE37834.1 - 1.8e-22 79.2 8.8 1.7e-05 24.8 0.0 5.2 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 EKE37834.1 - 3.1e-20 70.1 9.3 0.0077 16.0 0.1 6.3 6 0 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.27 EKE37834.1 - 3.8e-18 63.3 13.9 0.00012 21.0 0.1 6.5 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.1 EKE37834.1 - 1.1e-09 37.7 6.1 0.0023 17.5 0.0 5.4 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.1 EKE37834.1 - 4.9e-08 31.9 9.4 0.0027 16.9 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_10 PF14788.1 EKE37834.1 - 0.0003 20.3 7.9 4.8 6.9 0.1 5.2 4 1 1 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 EKE37834.1 - 0.00083 19.3 6.9 0.15 12.0 1.0 4.1 3 1 1 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EKE37834.1 - 0.007 16.2 0.0 5.8 6.9 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.2 EKE37834.1 - 0.0078 15.9 3.4 0.23 11.2 0.3 3.2 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand IL5 PF02025.10 EKE37834.1 - 0.016 15.2 0.3 0.45 10.5 0.1 2.4 2 0 0 2 2 2 0 Interleukin 5 DUF4194 PF13835.1 EKE37834.1 - 0.15 11.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) SGS PF05002.10 EKE37834.1 - 0.17 11.6 0.9 1.7 8.4 0.1 2.8 2 1 0 2 2 2 0 SGS domain Ribosomal_S24e PF01282.14 EKE37835.1 - 7.2e-28 96.2 0.2 1.2e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF1251 PF06856.6 EKE37835.1 - 0.035 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) DUF211 PF02680.9 EKE37835.1 - 0.12 12.2 0.1 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF1151 PF06625.6 EKE37836.1 - 0.0055 16.4 0.2 0.0092 15.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) Pox_T4_C PF04490.7 EKE37836.1 - 0.02 14.6 3.0 0.03 14.0 2.1 1.3 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus DUF2576 PF10845.3 EKE37836.1 - 0.045 12.9 0.1 2.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) TFX_C PF14601.1 EKE37836.1 - 0.054 13.2 0.4 0.14 11.9 0.3 1.7 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term RE_TdeIII PF09520.5 EKE37836.1 - 0.12 11.6 5.5 0.048 12.9 1.2 1.8 1 1 1 2 2 2 0 Type II restriction endonuclease, TdeIII DUF2321 PF10083.4 EKE37836.1 - 0.13 11.7 2.2 0.36 10.3 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) RhoGAP PF00620.22 EKE37837.1 - 1.5e-27 96.1 0.1 5.1e-27 94.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Syntaxin PF00804.20 EKE37837.1 - 0.057 13.5 3.7 0.16 12.1 1.9 2.3 2 0 0 2 2 2 0 Syntaxin GTP_EFTU PF00009.22 EKE37838.1 - 1.6e-36 125.5 0.0 2.4e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EKE37838.1 - 1.9e-30 104.7 0.1 6.2e-30 103.1 0.0 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EKE37838.1 - 4.6e-09 36.2 0.0 6.9e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKE37838.1 - 0.0088 15.9 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKE37838.1 - 0.071 12.9 0.9 0.36 10.6 0.6 2.3 1 1 0 1 1 1 0 Dynamin family ABC2_membrane_4 PF12730.2 EKE37839.1 - 0.0052 15.9 0.2 0.0066 15.6 0.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein RNase_H2-Ydr279 PF09468.5 EKE37841.1 - 0.033 13.3 1.5 0.11 11.6 0.1 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DUF1482 PF07358.6 EKE37841.1 - 5.7 6.6 6.4 7.9 6.1 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1482) HMGL-like PF00682.14 EKE37842.1 - 4 7.0 7.5 0.39 10.3 0.5 2.3 1 1 2 3 3 3 0 HMGL-like PGK PF00162.14 EKE37843.1 - 5.3e-147 489.3 0.0 6e-147 489.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Beach PF02138.13 EKE37845.1 - 7.3e-12 45.2 6.8 2.1e-11 43.7 1.2 3.3 2 1 1 3 3 3 1 Beige/BEACH domain SPARC_Ca_bdg PF10591.4 EKE37845.1 - 0.018 15.0 0.2 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region E1-E2_ATPase PF00122.15 EKE37846.1 - 3.5e-18 65.4 0.0 3.5e-18 65.4 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKE37846.1 - 2.4e-14 54.2 0.0 1.8e-13 51.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE37846.1 - 1.6e-13 51.2 0.0 5.2e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE37846.1 - 6.1e-11 42.1 0.1 7.4e-10 38.6 0.0 2.7 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKE37846.1 - 0.00066 19.3 1.6 0.0019 17.8 0.3 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Arrestin_N PF00339.24 EKE37847.1 - 4.9e-07 29.6 0.1 1.7e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain WW PF00397.21 EKE37847.1 - 1.4e-06 28.0 3.9 5.4e-05 22.9 0.3 3.5 3 0 0 3 3 3 2 WW domain Rad52_Rad22 PF04098.10 EKE37848.1 - 2.6e-45 153.8 0.0 4.2e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DndB PF14072.1 EKE37848.1 - 0.0072 15.5 0.5 0.0099 15.0 0.4 1.1 1 0 0 1 1 1 1 DNA-sulfur modification-associated Band_3_cyto PF07565.8 EKE37848.1 - 0.07 12.6 1.2 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FF PF01846.14 EKE37849.1 - 0.00064 19.6 9.5 0.047 13.6 0.3 3.4 4 0 0 4 4 4 2 FF domain WW PF00397.21 EKE37849.1 - 0.0073 16.1 4.0 1.8 8.5 0.0 2.9 3 0 0 3 3 3 2 WW domain PSDC PF12588.3 EKE37849.1 - 0.16 11.5 4.3 0.092 12.3 0.7 2.2 2 0 0 2 2 2 0 Phophatidylserine decarboxylase DUF2265 PF10023.4 EKE37849.1 - 0.97 8.5 12.6 0.77 8.8 1.3 2.3 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) OppC_N PF12911.2 EKE37850.1 - 0.0094 15.3 0.1 0.0094 15.3 0.1 1.9 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C TRP PF06011.7 EKE37850.1 - 0.11 11.0 10.3 0.024 13.2 4.9 1.5 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel DUF1230 PF06799.6 EKE37850.1 - 1.2 9.0 5.7 12 5.7 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) DUF3810 PF12725.2 EKE37850.1 - 2.4 6.9 6.1 6.6 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) NT-C2 PF10358.4 EKE37851.1 - 0.031 13.7 15.2 0.07 12.6 10.6 1.7 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF1043 PF06295.7 EKE37852.1 - 0.03 13.9 0.0 0.03 13.9 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Fzo_mitofusin PF04799.8 EKE37852.1 - 0.1 11.9 0.2 0.1 11.9 0.1 1.6 2 0 0 2 2 2 0 fzo-like conserved region Lge1 PF11488.3 EKE37852.1 - 0.63 10.2 0.1 0.63 10.2 0.0 2.7 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Presenilin PF01080.12 EKE37853.1 - 7.8e-71 239.0 34.3 1.7e-48 165.4 16.1 2.9 1 1 2 3 3 3 2 Presenilin Alg14 PF08660.6 EKE37853.1 - 0.0016 18.4 1.4 0.0033 17.4 1.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Endomucin PF07010.7 EKE37853.1 - 8.1 5.6 8.3 19 4.5 0.0 2.2 2 0 0 2 2 2 0 Endomucin DUF1632 PF07857.7 EKE37854.1 - 1.6e-55 188.1 3.8 2.4e-55 187.5 2.6 1.2 1 0 0 1 1 1 1 CEO family (DUF1632) Sugar_transport PF06800.7 EKE37854.1 - 9.9e-11 41.2 17.8 1.8e-06 27.2 5.7 3.1 2 1 1 3 3 3 2 Sugar transport protein NicO PF03824.11 EKE37854.1 - 0.012 14.9 0.5 0.012 14.9 0.4 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF2975 PF11188.3 EKE37854.1 - 0.017 14.8 0.7 0.017 14.8 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) DUF3677 PF12432.3 EKE37855.1 - 0.0011 19.3 0.1 0.11 12.9 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3677) WH2 PF02205.15 EKE37857.1 - 8e-06 25.2 0.1 2.2e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 WH2 motif RasGEF PF00617.14 EKE37857.1 - 0.038 13.7 1.3 0.069 12.8 0.9 1.4 1 0 0 1 1 1 0 RasGEF domain MAS20 PF02064.10 EKE37857.1 - 0.16 11.9 1.0 0.37 10.7 0.7 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor OATP PF03137.15 EKE37857.1 - 0.36 8.8 2.1 0.39 8.7 0.9 1.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ThylakoidFormat PF11264.3 EKE37857.1 - 0.37 10.3 5.6 4 7.0 0.5 2.3 1 1 1 2 2 2 0 Thylakoid formation protein Atg14 PF10186.4 EKE37857.1 - 0.41 9.5 5.6 0.044 12.7 1.1 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Trypsin_2 PF13365.1 EKE37858.1 - 1.9e-05 24.6 0.0 0.00053 19.9 0.0 2.4 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.16 EKE37858.1 - 0.32 10.3 3.5 1.6 8.1 2.5 2.2 1 1 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease SapB_1 PF05184.10 EKE37858.1 - 7 6.6 8.4 0.75 9.6 1.3 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 PX PF00787.19 EKE37860.1 - 1.5e-17 63.4 0.6 2.9e-17 62.4 0.4 1.5 1 0 0 1 1 1 1 PX domain TNF PF00229.13 EKE37860.1 - 0.04 13.4 0.3 0.065 12.7 0.2 1.3 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Gp_dh_N PF00044.19 EKE37860.1 - 0.078 12.9 1.5 0.18 11.7 0.4 1.8 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IncFII_repA PF02387.10 EKE37860.1 - 6.5 5.8 7.7 3.2 6.8 2.6 2.1 2 0 0 2 2 2 0 IncFII RepA protein family Rhomboid PF01694.17 EKE37861.1 - 2e-13 50.5 13.1 2e-13 50.5 9.1 2.2 3 0 0 3 3 3 1 Rhomboid family TMEM141 PF15110.1 EKE37861.1 - 0.052 13.8 0.5 0.18 12.1 0.3 2.0 1 0 0 1 1 1 0 TMEM141 protein family DUF2231 PF09990.4 EKE37861.1 - 0.11 12.8 0.6 0.11 12.8 0.4 2.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) PALP PF00291.20 EKE37862.1 - 1.3e-55 188.8 0.7 1.5e-55 188.6 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PROCN PF08083.6 EKE37863.1 - 7.6e-201 666.8 11.0 1.2e-200 666.1 7.6 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EKE37863.1 - 3.8e-100 333.9 0.2 7.1e-100 333.0 0.1 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EKE37863.1 - 6.2e-91 301.9 1.3 1.6e-90 300.5 0.9 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EKE37863.1 - 2.3e-73 244.8 1.0 6.1e-73 243.4 0.7 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EKE37863.1 - 2e-65 218.4 0.4 4.4e-65 217.3 0.3 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EKE37863.1 - 6e-39 131.7 0.3 6e-39 131.7 0.2 2.2 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EKE37863.1 - 4.9e-27 94.1 0.0 2e-26 92.1 0.0 2.1 1 0 0 1 1 1 1 PROCT (NUC072) domain Pkinase PF00069.20 EKE37865.1 - 1e-60 205.0 0.7 4.7e-60 202.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37865.1 - 5.5e-34 117.3 0.0 1.3e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE37865.1 - 3.1e-09 36.9 0.2 1.1e-08 35.1 0.1 2.1 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EKE37865.1 - 2e-08 33.5 0.0 1e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EKE37865.1 - 8.1e-05 22.4 0.0 0.0057 16.4 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKE37865.1 - 0.0044 16.3 0.1 0.016 14.5 0.0 2.0 1 0 0 1 1 1 1 RIO1 family PH_9 PF15410.1 EKE37865.1 - 0.0077 16.3 0.1 0.072 13.2 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain EMG1 PF03587.9 EKE37867.1 - 1.7e-64 216.8 0.0 1.9e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pkinase_Tyr PF07714.12 EKE37868.1 - 4.6e-56 189.7 0.3 1.1e-55 188.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37868.1 - 1e-54 185.4 0.0 1.8e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.1 EKE37868.1 - 0.03 14.0 0.1 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family YajC PF02699.10 EKE37868.1 - 0.067 12.8 0.6 0.17 11.6 0.4 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit VSP PF03302.8 EKE37868.1 - 0.074 11.6 159.8 0.05 12.2 20.5 7.0 3 2 4 7 7 7 0 Giardia variant-specific surface protein EphA2_TM PF14575.1 EKE37868.1 - 0.12 12.8 0.5 0.32 11.4 0.3 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2500 PF10694.4 EKE37868.1 - 0.19 11.7 0.6 0.47 10.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF4010 PF13194.1 EKE37868.1 - 0.26 10.5 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) FixG_C PF11614.3 EKE37868.1 - 0.26 11.3 0.0 0.48 10.5 0.0 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase zf-rbx1 PF12678.2 EKE37870.1 - 4.3e-33 113.2 10.1 5e-33 113.0 7.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EKE37870.1 - 3.1e-18 65.4 7.5 3.5e-18 65.2 5.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EKE37870.1 - 1.2e-07 31.4 12.7 8.6e-07 28.6 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKE37870.1 - 0.00025 20.6 10.6 0.0019 17.8 7.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 EKE37870.1 - 0.0015 18.5 3.1 0.002 18.1 2.2 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.1 EKE37870.1 - 0.0023 17.5 9.9 0.2 11.3 7.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE37870.1 - 0.033 14.1 10.6 0.59 10.2 7.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bacteriocin_II PF01721.13 EKE37870.1 - 0.058 12.9 0.5 0.097 12.2 0.3 1.3 1 0 0 1 1 1 0 Class II bacteriocin FANCL_C PF11793.3 EKE37870.1 - 0.065 13.1 8.4 0.12 12.3 5.8 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EKE37870.1 - 0.067 12.9 11.0 0.5 10.1 7.6 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 EKE37870.1 - 0.083 12.4 1.7 0.12 11.8 1.2 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 EKE37870.1 - 0.98 9.6 9.8 5.7 7.1 6.3 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EKE37870.1 - 1.3 8.8 6.5 91 2.8 4.5 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EKE37870.1 - 1.5 8.6 5.2 0.54 10.0 1.6 1.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein RINGv PF12906.2 EKE37870.1 - 4.6 7.3 15.4 24 5.0 6.7 2.7 1 1 2 3 3 3 0 RING-variant domain PHD PF00628.24 EKE37870.1 - 6 6.6 12.2 47 3.7 8.5 2.1 1 1 0 1 1 1 0 PHD-finger HEAT PF02985.17 EKE37871.1 - 3e-06 26.8 5.6 17 5.8 0.1 8.6 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.1 EKE37871.1 - 5.4e-06 26.6 0.0 4.9 7.5 0.0 5.7 4 1 1 5 5 5 2 HEAT repeats DUF1804 PF08822.6 EKE37871.1 - 0.01 15.5 0.2 4.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1804) Vac14_Fab1_bd PF12755.2 EKE37871.1 - 0.019 15.3 0.8 15 6.0 0.0 4.1 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 EKE37871.1 - 0.05 13.5 1.0 5.3 7.0 0.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) DUF3579 PF12112.3 EKE37871.1 - 0.11 12.4 0.7 3.3 7.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3579) PseudoU_synth_1 PF01416.15 EKE37872.1 - 7.1e-29 100.3 0.0 1.5e-17 63.9 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ank_4 PF13637.1 EKE37873.1 - 0.086 13.3 0.1 0.23 12.0 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 EKE37874.1 - 7.1e-38 130.1 0.0 1.9e-37 128.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37874.1 - 9.2e-34 116.7 1.6 4.4e-33 114.5 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.2 EKE37874.1 - 1.6e-12 46.7 35.2 0.0044 16.6 0.7 6.8 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE37874.1 - 4.6e-12 45.4 21.4 1.7e-05 24.4 1.8 5.0 2 2 0 3 3 3 3 Leucine rich repeat Myotub-related PF06602.9 EKE37874.1 - 2.3e-11 43.0 3.8 9.7e-11 41.0 2.6 1.9 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain LRR_1 PF00560.28 EKE37874.1 - 6.5e-05 22.4 28.0 2.4 8.4 2.0 9.4 8 0 0 8 8 8 2 Leucine Rich Repeat HHH_5 PF14520.1 EKE37874.1 - 0.28 11.4 0.0 24 5.2 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain LRR_7 PF13504.1 EKE37874.1 - 2.1 8.9 19.1 2.9 8.4 0.6 7.3 7 0 0 7 7 7 0 Leucine rich repeat Syntaphilin PF15290.1 EKE37875.1 - 0.014 14.8 9.0 0.03 13.7 6.2 1.5 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp WWE PF02825.15 EKE37876.1 - 0.0014 18.0 0.8 0.0032 16.8 0.5 1.6 1 0 0 1 1 1 1 WWE domain hSH3 PF14603.1 EKE37876.1 - 0.0038 17.1 0.4 0.15 12.1 0.0 2.8 2 1 1 3 3 3 1 Helically-extended SH3 domain BRCT PF00533.21 EKE37876.1 - 0.02 15.0 0.3 0.065 13.3 0.2 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RhoGAP PF00620.22 EKE37877.1 - 7.1e-15 54.9 1.1 4.1e-14 52.4 0.8 2.4 1 0 0 1 1 1 1 RhoGAP domain DUF4239 PF14023.1 EKE37877.1 - 0.23 10.8 4.0 0.22 10.8 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) Sec1 PF00995.18 EKE37878.1 - 2e-114 383.2 11.0 2.3e-114 383.0 7.6 1.0 1 0 0 1 1 1 1 Sec1 family Abhydrolase_5 PF12695.2 EKE37879.1 - 0.0075 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE37879.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EKE37880.1 - 4.4e-72 242.3 1.2 5.6e-72 242.0 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37880.1 - 2.9e-42 144.5 0.8 3.8e-42 144.1 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKE37880.1 - 1.1e-08 35.0 0.4 2.5e-08 33.9 0.3 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EKE37880.1 - 6.6e-07 28.5 0.0 7.7e-05 21.7 0.0 2.1 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 EKE37880.1 - 0.00088 18.6 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EKE37880.1 - 0.007 15.7 0.5 0.013 14.8 0.3 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EKE37880.1 - 0.0083 15.2 0.2 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE37880.1 - 0.046 13.4 0.0 5.1 6.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EKE37883.1 - 6.4e-53 179.5 0.0 7.9e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37883.1 - 2e-20 72.9 0.0 6e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37883.1 - 0.00058 18.9 0.1 0.0056 15.6 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EKE37883.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EKE37883.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0184 PF03670.8 EKE37885.1 - 0.025 14.7 1.5 0.049 13.8 0.1 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) BLOC1_2 PF10046.4 EKE37885.1 - 0.079 13.1 3.0 0.093 12.8 1.7 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Thioredoxin_7 PF13899.1 EKE37885.1 - 0.083 12.9 0.1 0.11 12.5 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like CRISPR_Cas2 PF09827.4 EKE37885.1 - 0.13 12.3 1.2 0.16 12.0 0.9 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Mto2_bdg PF12808.2 EKE37885.1 - 0.14 12.3 3.8 0.18 11.9 2.6 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1366 PF07104.6 EKE37885.1 - 0.23 11.0 4.7 0.26 10.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) SlyX PF04102.7 EKE37885.1 - 0.29 11.5 3.0 0.37 11.1 2.1 1.2 1 0 0 1 1 1 0 SlyX HlyD_2 PF12700.2 EKE37885.1 - 0.94 8.5 8.8 1.1 8.4 6.1 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF3847 PF12958.2 EKE37885.1 - 1.4 8.6 7.7 24 4.7 4.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DivIC PF04977.10 EKE37885.1 - 1.6 8.2 7.3 0.84 9.1 3.1 1.9 1 1 1 2 2 2 0 Septum formation initiator DivIC PF04977.10 EKE37886.1 - 0.0043 16.5 2.6 0.012 15.1 0.6 2.0 2 0 0 2 2 2 1 Septum formation initiator Kinesin-related PF06548.6 EKE37886.1 - 0.015 13.8 0.8 0.015 13.8 0.5 1.2 1 0 0 1 1 1 0 Kinesin-related KIAA1430 PF13879.1 EKE37886.1 - 0.036 14.4 0.6 0.046 14.1 0.4 1.2 1 0 0 1 1 1 0 KIAA1430 homologue DUF2095 PF09868.4 EKE37886.1 - 0.72 9.6 4.2 1.4 8.7 2.9 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DUF2205 PF10224.4 EKE37887.1 - 0.036 13.6 7.3 0.16 11.5 0.0 3.1 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) HALZ PF02183.13 EKE37887.1 - 0.14 11.8 3.7 7.4 6.3 0.1 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 EKE37887.1 - 0.26 11.6 6.7 0.44 10.9 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EKE37887.1 - 1.4 8.8 7.7 2.1 8.3 1.5 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family YscO PF07321.7 EKE37887.1 - 1.5 8.6 6.7 1.1 9.0 1.7 2.2 2 1 0 2 2 2 0 Type III secretion protein YscO WD40 PF00400.27 EKE37888.1 - 1e-17 63.2 6.9 3.9e-08 32.8 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat F-box PF00646.28 EKE37888.1 - 0.013 15.1 0.0 0.04 13.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain E1_DerP2_DerF2 PF02221.10 EKE37889.1 - 3.2e-18 66.2 1.8 3.8e-18 66.0 1.2 1.1 1 0 0 1 1 1 1 ML domain Tricho_coat PF05892.6 EKE37889.1 - 0.035 13.3 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Trichovirus coat protein eIF-5a PF01287.15 EKE37890.1 - 6e-24 83.7 0.3 8.5e-24 83.3 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 EKE37890.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 EKE37890.1 - 0.0043 16.7 0.2 0.0082 15.8 0.1 1.5 1 0 0 1 1 1 1 KOW motif IF4E PF01652.13 EKE37891.1 - 1.3e-18 67.0 0.4 1.9e-18 66.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RhoGEF PF00621.15 EKE37892.1 - 3.6e-71 238.7 38.7 1e-28 100.4 2.4 5.5 5 0 0 5 5 5 3 RhoGEF domain BRCT PF00533.21 EKE37894.1 - 9.2e-06 25.7 5.6 0.0036 17.3 0.1 4.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BSD PF03909.12 EKE37894.1 - 0.18 11.5 5.6 0.19 11.4 1.5 2.6 2 0 0 2 2 2 0 BSD domain DTW PF03942.10 EKE37895.1 - 2.9e-20 72.3 2.5 3.8e-20 71.9 1.7 1.2 1 0 0 1 1 1 1 DTW domain zf-RING_3 PF14369.1 EKE37895.1 - 2 8.4 10.9 0.62 10.1 0.1 3.1 3 0 0 3 3 3 0 zinc-finger zf-B_box PF00643.19 EKE37895.1 - 2.2 8.2 12.8 0.088 12.7 4.6 1.9 2 0 0 2 2 2 0 B-box zinc finger DUF3184 PF11380.3 EKE37896.1 - 1e-05 23.7 0.9 0.00084 17.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) IncA PF04156.9 EKE37896.1 - 0.058 12.9 0.3 0.098 12.2 0.2 1.2 1 0 0 1 1 1 0 IncA protein AATF-Che1 PF13339.1 EKE37897.1 - 1.5 9.0 8.7 0.13 12.4 1.6 2.3 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor EF-hand_1 PF00036.27 EKE37898.1 - 1.9e-15 54.8 12.1 0.00015 20.7 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKE37898.1 - 4.8e-15 55.4 10.1 2.3e-07 30.8 0.4 2.5 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE37898.1 - 4.2e-12 44.8 12.6 0.024 14.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKE37898.1 - 2.3e-11 42.5 12.0 0.0044 16.2 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EKE37898.1 - 7.7e-11 41.4 12.9 9.1e-06 25.2 1.2 4.0 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKE37898.1 - 1.7e-05 24.8 0.1 0.17 11.9 0.0 2.9 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EKE37898.1 - 4.1e-05 23.4 0.2 0.037 13.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.2 EKE37898.1 - 0.24 11.1 7.9 1.2 8.9 0.2 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.13 EKE37898.1 - 0.64 9.8 5.0 5.4 6.8 0.1 2.8 2 0 0 2 2 2 0 Dockerin type I repeat SPRY PF00622.23 EKE37899.1 - 1.2e-11 44.7 0.1 2.7e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 SPRY domain Sec63 PF02889.11 EKE37900.1 - 4.9e-16 58.8 7.6 6.6e-16 58.4 5.3 1.2 1 0 0 1 1 1 1 Sec63 Brl domain TMEM117 PF15113.1 EKE37900.1 - 0.00045 18.9 1.5 0.0005 18.7 0.2 1.7 2 0 0 2 2 2 1 TMEM117 protein family ASFV_J13L PF05568.6 EKE37900.1 - 0.31 10.5 3.5 4.1 6.9 0.5 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein NAD_kinase PF01513.16 EKE37901.1 - 9.9e-19 67.1 0.0 1.2e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EKE37901.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Hydrolase_3 PF08282.7 EKE37902.1 - 9.7e-39 133.4 0.0 2.2e-38 132.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE37902.1 - 1.2e-06 28.7 0.1 6.6e-05 23.1 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE37902.1 - 0.002 18.5 0.0 0.063 13.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aa_trans PF01490.13 EKE37903.1 - 1.2e-26 93.1 38.9 1.7e-26 92.6 27.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EKE37903.1 - 0.41 9.4 32.0 4.5 5.9 22.2 2.7 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family Pkinase PF00069.20 EKE37904.1 - 4.6e-29 101.3 0.0 5.8e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37904.1 - 2e-13 50.0 0.0 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE37904.1 - 0.027 14.2 0.0 0.061 13.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family L_protein_N PF15518.1 EKE37904.1 - 0.054 12.8 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 L protein N-terminus zf-RING_2 PF13639.1 EKE37905.1 - 3.3e-12 46.0 8.6 8.6e-12 44.6 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKE37905.1 - 3.6e-08 33.4 8.3 3.6e-08 33.4 5.8 2.2 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EKE37905.1 - 5e-08 32.4 4.7 1.4e-07 31.1 3.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE37905.1 - 4e-06 26.7 9.1 1.2e-05 25.1 6.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE37905.1 - 5.3e-06 26.0 6.1 1.1e-05 24.9 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EKE37905.1 - 3.2e-05 23.4 8.8 9e-05 22.0 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EKE37905.1 - 0.0007 19.3 5.3 0.002 17.8 3.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EKE37905.1 - 0.012 15.5 5.1 0.052 13.5 3.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EKE37905.1 - 0.022 14.4 3.1 0.022 14.4 2.2 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Rtf2 PF04641.7 EKE37905.1 - 0.072 12.2 0.5 0.21 10.7 0.1 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.1 EKE37905.1 - 0.27 10.8 3.9 0.82 9.3 2.7 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EKE37905.1 - 0.43 10.6 6.4 1.2 9.1 4.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 EKE37905.1 - 1.3 8.6 5.1 2.5 7.7 2.8 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EKE37905.1 - 1.8 8.3 6.4 19 5.1 3.1 2.8 2 1 0 2 2 2 0 zf-RING of BARD1-type protein TLD PF07534.11 EKE37906.1 - 0.00039 20.4 0.2 0.0008 19.4 0.1 1.6 1 0 0 1 1 1 1 TLD VPS9 PF02204.13 EKE37907.1 - 3.5e-17 62.3 3.6 8.8e-17 61.0 2.5 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RRM_1 PF00076.17 EKE37908.1 - 1.4e-14 53.4 0.0 3e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE37908.1 - 7.4e-10 38.6 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EKE37908.1 - 2.6e-09 36.5 2.3 5.5e-09 35.5 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle MIP-T3 PF10243.4 EKE37908.1 - 2.4e-07 29.6 58.1 2.4e-07 29.6 40.3 1.3 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 EKE37908.1 - 3.3e-06 26.0 27.2 3.3e-06 26.0 18.9 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RRM_5 PF13893.1 EKE37908.1 - 0.0003 20.5 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 EKE37908.1 - 0.0048 15.2 18.7 0.0043 15.4 13.0 1.1 1 0 0 1 1 1 1 Transmembrane protein Nop14 PF04147.7 EKE37908.1 - 0.87 7.4 58.7 1.2 7.0 40.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 EKE37908.1 - 2.6 7.1 68.3 0.054 12.7 43.0 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PLRV_ORF5 PF01690.12 EKE37908.1 - 4.2 6.3 33.6 5.8 5.9 23.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 EKE37908.1 - 6.7 5.0 55.7 10 4.4 38.6 1.2 1 0 0 1 1 1 0 Daxx Family Ndc1_Nup PF09531.5 EKE37908.1 - 8.3 4.7 15.7 9.6 4.4 10.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1777 PF08648.7 EKE37908.1 - 8.8 6.0 43.3 2 8.1 25.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Lectin_leg-like PF03388.8 EKE37909.1 - 2.5e-21 75.8 0.0 2.5e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Legume-like lectin family DsbB PF02600.11 EKE37909.1 - 0.052 13.3 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB SprA-related PF12118.3 EKE37909.1 - 6.4 6.0 28.6 9.7 5.4 19.8 1.1 1 0 0 1 1 1 0 SprA-related family Radical_SAM PF04055.16 EKE37910.1 - 6.6e-16 58.9 1.9 7.5e-16 58.7 0.4 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EKE37910.1 - 7.4e-10 38.7 0.0 1.8e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RhoGEF PF00621.15 EKE37911.1 - 2.7e-20 73.0 10.2 2.7e-20 73.0 7.1 3.1 3 1 0 3 3 3 1 RhoGEF domain IQ PF00612.22 EKE37911.1 - 0.0092 15.5 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif HECA PF15353.1 EKE37912.1 - 0.11 12.2 0.1 6.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Headcase protein family homologue Choline_kinase PF01633.15 EKE37914.1 - 0.0033 17.0 0.7 0.0056 16.2 0.5 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EKE37914.1 - 0.0056 15.8 0.1 0.0071 15.5 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EKE37914.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family ACDC PF14733.1 EKE37914.1 - 0.02 14.9 0.2 0.06 13.4 0.1 1.9 1 0 0 1 1 1 0 AP2-coincident C-terminal Pkinase_Tyr PF07714.12 EKE37914.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EKE37914.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF846 PF05832.7 EKE37915.1 - 3.5e-41 140.2 14.5 4.2e-41 139.9 10.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) MgtE PF01769.11 EKE37915.1 - 0.31 11.3 4.6 1.5 9.0 0.7 2.2 2 0 0 2 2 2 0 Divalent cation transporter DUF912 PF06024.7 EKE37915.1 - 0.76 9.8 2.7 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rer1 PF03248.8 EKE37915.1 - 7.4 6.1 8.8 13 5.2 6.1 1.5 1 1 0 1 1 1 0 Rer1 family zf-HIT PF04438.11 EKE37916.1 - 5.4e-06 25.9 6.9 8.6e-06 25.2 4.8 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 EKE37916.1 - 0.082 12.7 3.5 0.16 11.8 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_6 PF14835.1 EKE37916.1 - 0.24 11.1 1.6 0.3 10.8 0.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EKE37916.1 - 0.39 10.4 4.8 0.25 11.1 1.9 1.7 2 0 0 2 2 2 0 zinc-RING finger domain Proteasome PF00227.21 EKE37917.1 - 4.6e-37 127.1 0.2 5.4e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit SH3_1 PF00018.23 EKE37918.1 - 3e-15 55.3 0.0 5.7e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKE37918.1 - 3.1e-13 49.0 0.0 4.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE37918.1 - 1.8e-11 43.3 0.0 4.7e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EKE37918.1 - 4.1e-08 33.3 2.5 6.5e-08 32.6 0.1 2.5 1 1 2 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Myosin_tail_1 PF01576.14 EKE37918.1 - 0.00046 18.0 8.0 0.00046 18.0 5.6 1.4 2 0 0 2 2 2 1 Myosin tail Peptidase_S46 PF10459.4 EKE37918.1 - 0.0039 15.6 9.0 0.0057 15.1 6.3 1.3 1 0 0 1 1 1 1 Peptidase S46 Fib_alpha PF08702.5 EKE37918.1 - 0.043 13.9 0.9 0.043 13.9 0.6 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family YppF PF14178.1 EKE37918.1 - 0.1 12.1 0.5 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 YppF-like protein SpoIISA_toxin PF14171.1 EKE37918.1 - 0.26 10.4 8.8 0.31 10.2 1.3 2.3 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Spectrin PF00435.16 EKE37918.1 - 0.32 11.3 7.5 0.14 12.4 2.1 2.6 1 1 1 2 2 2 0 Spectrin repeat ATP-synt_F6 PF05511.6 EKE37918.1 - 1.5 8.7 8.1 0.36 10.7 0.9 2.6 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 IncA PF04156.9 EKE37918.1 - 2.9 7.4 6.7 8.3 5.9 4.6 1.8 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 EKE37918.1 - 8.2 6.3 7.6 8.7 6.2 1.1 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2681 PF10883.3 EKE37919.1 - 0.048 13.8 0.7 0.13 12.4 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) FixQ PF05545.6 EKE37919.1 - 0.17 11.5 1.8 0.35 10.5 1.2 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ IPK PF03770.11 EKE37920.1 - 2.5e-38 131.7 0.9 3.3e-38 131.3 0.6 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase CPSF_A PF03178.10 EKE37921.1 - 2e-37 129.0 0.8 2e-37 129.0 0.6 1.6 2 0 0 2 2 2 1 CPSF A subunit region UBA PF00627.26 EKE37922.1 - 6.8e-15 54.4 2.5 1.1e-06 28.2 0.0 3.2 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 EKE37922.1 - 1.1e-10 40.7 0.2 2.4e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE37922.1 - 3.8e-05 23.2 0.2 8e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RecX PF02631.11 EKE37922.1 - 0.0019 18.3 0.5 0.73 10.0 0.0 2.9 3 0 0 3 3 3 1 RecX family UBA_2 PF08587.6 EKE37922.1 - 0.0054 16.8 0.3 0.031 14.4 0.2 2.4 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) UBA_3 PF09288.5 EKE37922.1 - 0.015 14.9 0.2 0.077 12.6 0.1 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain XPC-binding PF09280.6 EKE37922.1 - 0.13 11.7 3.9 0.35 10.3 2.7 1.8 1 0 0 1 1 1 0 XPC-binding domain HBS1_N PF08938.5 EKE37922.1 - 2.2 8.4 0.0 2.2 8.4 0.0 4.4 3 1 0 3 3 3 0 HBS1 N-terminus Pex14_N PF04695.8 EKE37922.1 - 2.6 8.1 9.8 4.3 7.3 2.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha-amylase PF00128.19 EKE37923.1 - 3.5e-19 69.3 0.1 1.8e-16 60.4 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EKE37923.1 - 8.8e-19 67.4 0.0 2.2e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 EKE37923.1 - 2.7e-06 27.3 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GHL6 PF14871.1 EKE37923.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 PTCB-BRCT PF12738.2 EKE37924.1 - 0.00013 21.7 0.5 0.00029 20.6 0.3 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKE37924.1 - 0.00033 20.7 0.4 0.00033 20.7 0.3 3.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Spc7 PF08317.6 EKE37924.1 - 0.0089 14.7 40.8 0.011 14.4 18.3 2.7 1 1 1 2 2 2 2 Spc7 kinetochore protein Cep57_CLD_2 PF14197.1 EKE37924.1 - 0.1 12.5 22.0 0.24 11.3 2.8 3.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMF_TATA_bd PF12325.3 EKE37924.1 - 0.13 11.9 28.7 1.1 8.9 6.3 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NYD-SP28_assoc PF14775.1 EKE37924.1 - 0.14 11.8 0.3 0.14 11.8 0.2 4.6 5 1 0 5 5 5 0 Sperm tail C-terminal domain FUSC PF04632.7 EKE37924.1 - 0.24 9.7 0.4 0.32 9.3 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Methyltransf_15 PF09445.5 EKE37924.1 - 1.2 8.7 5.8 1.8 8.1 0.7 2.4 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DUF1664 PF07889.7 EKE37924.1 - 1.6 8.5 28.2 0.88 9.3 8.1 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EKE37924.1 - 1.8 8.3 37.4 2.6 7.8 8.9 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 EKE37924.1 - 4.6 7.1 20.4 21 5.0 4.2 3.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 EKE37924.1 - 9.9 5.0 32.9 22 3.9 11.5 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 CDP-OH_P_transf PF01066.16 EKE37926.1 - 3.8e-19 68.8 2.5 3.8e-19 68.8 1.7 3.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF4118 PF13493.1 EKE37926.1 - 0.031 14.4 1.7 0.031 14.4 1.2 4.6 3 1 1 5 5 5 0 Domain of unknown function (DUF4118) Ras PF00071.17 EKE37927.1 - 1.2e-50 171.0 1.3 1.4e-50 170.8 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37927.1 - 1.3e-16 61.1 0.4 2.5e-16 60.2 0.3 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE37927.1 - 4.1e-13 48.9 0.5 5e-13 48.6 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE37927.1 - 2.7e-09 36.7 0.8 5.1e-08 32.5 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE37927.1 - 3e-06 27.1 0.0 4.4e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE37927.1 - 5.8e-05 22.3 0.4 7.2e-05 22.0 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE37927.1 - 0.00029 20.0 0.1 0.0004 19.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EKE37927.1 - 0.0045 16.8 0.1 0.0059 16.4 0.1 1.6 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EKE37927.1 - 0.0071 15.6 0.3 1.7 7.9 0.2 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP-synt_ab PF00006.20 EKE37927.1 - 0.024 14.1 0.0 0.031 13.7 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain adh_short PF00106.20 EKE37928.1 - 1e-17 64.5 0.0 3.1e-17 63.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EKE37928.1 - 1.5e-08 34.3 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKE37928.1 - 1.7e-07 31.4 0.0 4.8e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKE37928.1 - 2.8e-07 30.3 0.0 4.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EKE37928.1 - 1.6e-06 27.2 0.0 2.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EKE37928.1 - 3.5e-05 22.8 0.1 4.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EKE37928.1 - 0.00098 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EKE37928.1 - 0.039 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.14 EKE37928.1 - 0.096 11.7 0.2 0.26 10.3 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase_Tyr PF07714.12 EKE37929.1 - 6.3e-50 169.6 0.0 1e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37929.1 - 6.9e-43 146.6 0.0 1.3e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain D123 PF07065.9 EKE37930.1 - 3.8e-30 104.9 10.1 4.9e-30 104.6 7.0 1.1 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EKE37930.1 - 5.2e-07 29.5 0.2 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) YcxB PF14317.1 EKE37930.1 - 0.042 13.0 3.7 0.084 12.1 0.5 2.6 2 0 0 2 2 2 0 YcxB-like protein PCNA_N PF00705.13 EKE37931.1 - 1.7e-32 111.6 2.7 1.7e-32 111.6 1.9 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EKE37931.1 - 1.9e-27 95.7 2.2 6.1e-27 94.0 0.1 2.3 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EKE37931.1 - 0.012 14.8 1.8 0.021 13.9 1.2 1.5 1 1 0 1 1 1 0 Rad9 Hus1 PF04005.7 EKE37931.1 - 0.028 13.3 0.2 0.097 11.6 0.1 1.6 1 1 0 1 1 1 0 Hus1-like protein DUF555 PF04475.7 EKE37931.1 - 0.068 13.1 0.1 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Oxysterol_BP PF01237.13 EKE37932.1 - 3.6e-71 239.4 0.0 3.6e-71 239.4 0.0 2.5 2 1 1 3 3 3 1 Oxysterol-binding protein HAD_2 PF13419.1 EKE37933.1 - 6.8e-13 49.2 0.0 8.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE37933.1 - 1.8e-05 24.9 0.0 2.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE37933.1 - 4.5e-05 23.0 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4538 PF15061.1 EKE37934.1 - 0.94 8.8 3.2 3 7.2 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Myb_DNA-bind_4 PF13837.1 EKE37935.1 - 6.5e-06 26.1 1.0 9.5e-06 25.6 0.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain IL5 PF02025.10 EKE37935.1 - 0.032 14.2 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Interleukin 5 FHIPEP PF00771.15 EKE37935.1 - 0.052 11.8 0.1 0.055 11.7 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Myb_DNA-bind_3 PF12776.2 EKE37935.1 - 0.17 12.5 3.6 0.68 10.5 2.5 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain MutS_II PF05188.12 EKE37938.1 - 0.099 12.7 0.4 0.15 12.1 0.3 1.4 1 1 0 1 1 1 0 MutS domain II CD45 PF12567.3 EKE37938.1 - 0.26 11.1 1.8 0.41 10.5 1.2 1.2 1 0 0 1 1 1 0 Leukocyte receptor CD45 RasGEF PF00617.14 EKE37940.1 - 6e-48 163.0 1.2 1.2e-47 162.0 0.3 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE37940.1 - 1.1e-09 38.3 0.3 1.1e-09 38.3 0.2 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif zf-RING_4 PF14570.1 EKE37940.1 - 0.0012 18.4 6.4 0.0029 17.1 4.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EKE37940.1 - 0.032 14.0 10.3 0.097 12.5 7.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.9 EKE37940.1 - 0.21 11.0 5.8 0.65 9.5 4.0 1.9 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.1 EKE37940.1 - 0.22 11.2 9.4 1 9.1 6.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE37940.1 - 1 9.4 14.9 0.25 11.3 7.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Myb_DNA-binding PF00249.26 EKE37941.1 - 0.073 13.1 0.1 0.23 11.5 0.0 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF3184 PF11380.3 EKE37943.1 - 1.3e-06 26.7 0.2 0.017 13.0 0.0 3.4 3 1 1 4 4 4 3 Protein of unknown function (DUF3184) DUF1648 PF07853.6 EKE37943.1 - 0.11 12.0 0.7 0.2 11.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) C2 PF00168.25 EKE37944.1 - 2.8e-19 68.7 1.5 8e-16 57.6 0.1 3.1 3 0 0 3 3 3 2 C2 domain EF-hand_7 PF13499.1 EKE37944.1 - 2.6e-11 43.5 6.0 3e-07 30.4 0.3 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EKE37944.1 - 2.8e-11 41.8 3.0 0.00029 19.9 0.3 4.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EKE37944.1 - 3.6e-10 38.8 4.9 0.0011 18.6 0.2 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EKE37944.1 - 1.2e-08 34.4 1.9 0.00059 19.3 0.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EKE37944.1 - 0.00072 18.7 0.8 0.14 11.5 0.2 3.0 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.1 EKE37944.1 - 0.026 14.4 0.9 0.093 12.6 0.1 2.3 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.4 EKE37944.1 - 0.09 12.8 1.5 10 6.2 0.1 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MFS_1 PF07690.11 EKE37945.1 - 8.3e-28 97.1 7.6 7.1e-27 94.0 0.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EKE37945.1 - 0.00062 19.4 1.0 0.18 11.6 0.0 3.6 3 0 0 3 3 3 1 MFS_1 like family DUF1510 PF07423.6 EKE37945.1 - 0.0015 17.9 1.1 0.0028 17.0 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Tom22 PF04281.8 EKE37945.1 - 0.05 13.1 2.7 0.1 12.1 1.9 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TRAP_alpha PF03896.11 EKE37945.1 - 0.17 10.8 2.8 0.23 10.4 0.9 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid PF03115.9 EKE37945.1 - 0.32 9.2 1.2 0.43 8.7 0.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 EKE37945.1 - 1.4 6.8 8.5 2 6.3 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_12 PF13087.1 EKE37946.1 - 4.4e-43 146.9 0.2 1.3e-42 145.4 0.2 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKE37946.1 - 1e-34 120.1 0.0 3.2e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.5 EKE37946.1 - 8e-09 35.2 8.2 8e-09 35.2 5.7 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 EKE37946.1 - 2.4e-08 33.5 0.0 4.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKE37946.1 - 1.8e-07 30.9 0.0 4.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EKE37946.1 - 1.2e-06 28.1 0.3 1 8.7 0.0 3.5 2 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EKE37946.1 - 0.00047 19.2 0.6 0.19 10.6 0.0 3.7 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EKE37946.1 - 0.00098 18.3 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.16 EKE37946.1 - 0.00099 18.4 0.0 0.003 16.9 0.0 1.9 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EKE37946.1 - 0.0026 17.1 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EKE37946.1 - 0.003 17.1 0.0 0.008 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE37946.1 - 0.0032 17.2 0.2 0.019 14.6 0.0 2.4 3 0 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 EKE37946.1 - 0.004 17.3 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EKE37946.1 - 0.0042 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF258 PF03193.11 EKE37946.1 - 0.0052 15.9 0.0 0.014 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 EKE37946.1 - 0.0073 16.5 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EKE37946.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain SMC_N PF02463.14 EKE37946.1 - 0.014 14.6 0.3 0.55 9.4 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EKE37946.1 - 0.016 15.0 0.0 0.069 13.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EKE37946.1 - 0.019 15.7 0.2 0.1 13.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKE37946.1 - 0.02 14.7 0.2 2 8.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain Spuma_A9PTase PF03539.9 EKE37946.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) MobB PF03205.9 EKE37946.1 - 0.05 13.3 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EKE37946.1 - 0.083 11.7 0.0 0.17 10.7 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EKE37946.1 - 0.22 11.5 0.0 0.47 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Amino_oxidase PF01593.19 EKE37947.1 - 0.062 12.3 0.5 0.076 12.0 0.3 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase PRP38_assoc PF12871.2 EKE37947.1 - 5.8 7.5 46.5 2.7 8.5 30.2 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Fib_alpha PF08702.5 EKE37948.1 - 0.69 10.0 14.5 4.8 7.2 0.2 3.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF257 PF03192.8 EKE37949.1 - 0.0083 15.4 0.9 0.01 15.1 0.6 1.1 1 0 0 1 1 1 1 Pyrococcus protein of unknown function, DUF257 TMEM247 PF15444.1 EKE37950.1 - 7.7 6.2 11.0 1.3 8.7 4.2 1.8 1 1 1 2 2 2 0 Transmembrane protein 247 Ras PF00071.17 EKE37951.1 - 5.7e-52 175.3 0.0 6.8e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37951.1 - 2.5e-14 53.7 0.0 1.1e-13 51.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE37951.1 - 4.4e-09 35.8 0.0 6.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE37951.1 - 6.8e-05 22.1 0.0 0.00014 21.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE37951.1 - 0.0024 17.3 0.0 0.012 15.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE37951.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sec7 PF01369.15 EKE37952.1 - 9.9e-35 119.9 2.1 9.9e-35 119.9 1.4 2.7 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.5 EKE37952.1 - 3e-15 55.5 14.8 2.1e-14 52.8 0.8 5.6 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) zf-MYND PF01753.13 EKE37952.1 - 0.0013 18.5 11.2 0.0029 17.4 7.8 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EKE37952.1 - 0.0052 16.6 10.0 0.0083 15.9 5.3 2.5 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 DENN PF02141.16 EKE37953.1 - 5.4e-20 71.8 1.7 5.4e-20 71.8 1.2 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain SPA PF08616.5 EKE37953.1 - 4e-05 23.2 0.3 7.9e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Metallophos PF00149.23 EKE37954.1 - 9.5e-14 51.2 0.2 2.1e-13 50.1 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE37954.1 - 7.4e-11 42.1 0.1 1.1e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rad60-SLD PF11976.3 EKE37955.1 - 0.017 14.7 0.1 0.046 13.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TFIIA PF03153.8 EKE37955.1 - 1.3 8.7 20.8 2 8.2 14.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 EKE37955.1 - 1.9 7.8 12.5 3.3 7.0 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DNA_pol_A_exo1 PF01612.15 EKE37956.1 - 2.2e-42 144.5 1.0 4.5e-42 143.4 0.7 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 EKE37956.1 - 3.8e-08 32.9 0.0 1.5e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 HRDC domain SNARE PF05739.14 EKE37957.1 - 4.3e-07 29.5 3.7 4.3e-07 29.5 2.6 2.5 3 0 0 3 3 3 1 SNARE domain Pectate_lyase_3 PF12708.2 EKE37957.1 - 0.0087 16.2 0.3 0.011 15.8 0.2 1.2 1 0 0 1 1 1 1 Pectate lyase superfamily protein BLOC1_2 PF10046.4 EKE37957.1 - 0.0091 16.1 3.2 0.0091 16.1 2.2 2.4 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Viral_env_E26 PF11050.3 EKE37957.1 - 0.011 15.0 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 Spectrin PF00435.16 EKE37957.1 - 0.04 14.1 2.7 3.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Spectrin repeat DegS PF05384.6 EKE37957.1 - 0.047 12.9 3.0 2.4 7.3 0.3 2.3 2 0 0 2 2 2 0 Sensor protein DegS DUF3040 PF11239.3 EKE37957.1 - 0.047 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SLX9 PF15341.1 EKE37957.1 - 0.048 14.0 1.4 0.063 13.7 0.1 1.8 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF842 PF05811.8 EKE37957.1 - 0.061 12.7 0.2 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2562 PF10814.3 EKE37957.1 - 0.13 12.2 0.3 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) DUF3722 PF12519.3 EKE37957.1 - 0.33 10.1 2.0 1.4 8.1 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3722) ETRAMP PF09716.5 EKE37957.1 - 1.1 9.2 5.2 0.16 11.9 0.7 1.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SseC PF04888.7 EKE37957.1 - 1.8 7.8 13.6 1.3 8.2 0.3 2.7 2 1 1 3 3 3 0 Secretion system effector C (SseC) like family BTB_2 PF02214.17 EKE37959.1 - 6.9e-05 22.9 5.5 0.00035 20.7 0.5 2.9 3 1 0 3 3 3 1 BTB/POZ domain SPRY PF00622.23 EKE37959.1 - 0.017 15.1 0.2 0.05 13.6 0.1 1.8 2 0 0 2 2 2 0 SPRY domain DEAD PF00270.24 EKE37960.1 - 2.4e-39 134.5 0.2 8.4e-39 132.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE37960.1 - 2.8e-25 87.9 0.1 6.8e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE37960.1 - 0.0027 17.5 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.17 EKE37960.1 - 0.079 12.5 0.1 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Ribosomal_S28e PF01200.13 EKE37961.1 - 9.7e-29 98.9 2.5 1e-28 98.8 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Mic1 PF07035.7 EKE37963.1 - 8e-12 44.8 2.7 8e-12 44.8 1.9 1.5 1 1 1 2 2 2 1 Colon cancer-associated protein Mic1-like Vps39_1 PF10366.4 EKE37963.1 - 0.023 14.6 2.4 0.055 13.4 1.7 1.8 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 DUF2672 PF10878.3 EKE37963.1 - 0.13 12.0 3.9 0.078 12.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) Prp18 PF02840.10 EKE37963.1 - 0.19 11.5 1.7 1 9.1 1.2 2.1 1 1 0 1 1 1 0 Prp18 domain Glycos_transf_4 PF00953.16 EKE37964.1 - 2.9e-26 92.1 20.1 2.9e-26 92.1 13.9 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF1129 PF06570.6 EKE37964.1 - 0.012 14.9 1.3 0.012 14.9 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Ub-RnfH PF03658.9 EKE37965.1 - 0.022 14.6 0.6 0.075 12.9 0.4 1.9 1 0 0 1 1 1 0 RnfH family Ubiquitin Cnd1 PF12717.2 EKE37965.1 - 3.1 7.6 11.3 0.11 12.3 0.1 3.1 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ras_bdg_2 PF14847.1 EKE37966.1 - 0.0088 15.9 0.8 0.014 15.2 0.2 1.6 2 0 0 2 2 2 1 Ras-binding domain of Byr2 Rot1 PF10681.4 EKE37966.1 - 0.016 14.6 0.8 0.023 14.0 0.6 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal DUF3195 PF11424.3 EKE37966.1 - 0.029 14.5 3.5 0.09 12.9 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3195) DUF3846 PF12957.2 EKE37966.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3846) LRR_5 PF13306.1 EKE37967.1 - 4.8e-81 268.8 43.1 1.6e-29 102.2 2.4 4.0 1 1 3 5 5 5 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE37967.1 - 6.5e-18 64.2 2.4 0.0012 18.6 0.0 5.8 2 2 4 6 6 6 6 Leucine rich repeat FNIP PF05725.7 EKE37967.1 - 0.23 11.4 21.5 4.9 7.1 0.1 5.9 5 0 0 5 5 5 0 FNIP Repeat RNA_pol_Rpb1_3 PF04983.13 EKE37967.1 - 0.63 9.7 3.8 1 9.0 1.0 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 3 DUF2105 PF09878.4 EKE37968.1 - 0.00063 19.3 0.1 0.00071 19.2 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2105) DUF2870 PF11069.3 EKE37968.1 - 0.093 12.7 0.3 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Desmo_N PF06771.6 EKE37968.1 - 0.28 11.1 2.8 2.3 8.1 0.2 2.2 1 1 1 2 2 2 0 Viral Desmoplakin N-terminus Myosin_tail_1 PF01576.14 EKE37969.1 - 0.00054 17.8 3.5 0.00079 17.2 2.4 1.1 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.4 EKE37969.1 - 0.0012 18.7 5.3 0.0024 17.7 3.7 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sipho_Gp157 PF05565.6 EKE37969.1 - 0.0044 16.6 3.1 0.0094 15.5 2.1 1.5 1 0 0 1 1 1 1 Siphovirus Gp157 Cep57_CLD_2 PF14197.1 EKE37969.1 - 0.018 14.9 8.1 0.054 13.4 3.2 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DrsE_2 PF13686.1 EKE37969.1 - 0.024 14.4 1.8 0.068 12.9 1.2 1.7 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family DivIC PF04977.10 EKE37969.1 - 0.029 13.8 0.3 0.029 13.8 0.2 2.9 3 1 1 4 4 3 0 Septum formation initiator ADIP PF11559.3 EKE37969.1 - 0.032 14.1 4.5 0.066 13.1 3.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EKE37969.1 - 0.06 12.9 2.9 0.12 12.0 2.0 1.4 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EKE37969.1 - 0.07 12.9 9.0 1.8 8.4 5.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 EKE37969.1 - 0.11 12.3 5.4 2.1 8.2 0.7 3.1 3 0 0 3 3 3 0 Basic region leucine zipper Reo_sigmaC PF04582.7 EKE37969.1 - 0.17 11.0 5.6 0.05 12.7 1.7 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Microtub_assoc PF07989.6 EKE37969.1 - 0.24 11.2 5.3 0.2 11.4 0.7 2.7 2 1 0 2 2 2 0 Microtubule associated Nsp1_C PF05064.8 EKE37969.1 - 0.33 10.6 6.0 0.25 11.0 1.3 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 EKE37969.1 - 0.6 9.9 5.8 1.1 9.0 4.0 1.4 1 0 0 1 1 1 0 Tropomyosin like DivIVA PF05103.8 EKE37969.1 - 0.75 9.8 8.4 0.079 13.0 1.2 2.6 2 1 1 3 3 3 0 DivIVA protein Nup54 PF13874.1 EKE37969.1 - 1 9.0 4.7 0.26 10.9 0.6 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FAM183 PF14886.1 EKE37969.1 - 2.9 8.4 6.2 2.6 8.6 0.6 3.0 3 1 0 3 3 3 0 FAM183A and FAM183B related bZIP_1 PF00170.16 EKE37969.1 - 2.9 7.9 7.5 2.6 8.0 1.3 2.6 1 1 1 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 EKE37969.1 - 8 6.8 11.5 0.93 9.8 4.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TLD PF07534.11 EKE37971.1 - 3.8e-08 33.4 0.9 4.2e-08 33.2 0.7 1.1 1 0 0 1 1 1 1 TLD KID PF02524.9 EKE37971.1 - 1.6 9.1 8.0 1.5 9.2 0.4 3.3 3 0 0 3 3 3 0 KID repeat EF-hand_7 PF13499.1 EKE37972.1 - 5.6e-13 48.8 0.1 7.7e-07 29.1 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EKE37972.1 - 1.1e-12 46.2 1.3 0.00022 20.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EKE37972.1 - 7.3e-10 37.8 0.2 0.02 14.7 0.0 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EKE37972.1 - 1.3e-09 37.5 0.7 0.006 16.1 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EKE37972.1 - 4.7e-08 32.0 0.7 5e-05 22.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EKE37972.1 - 4.4e-07 29.7 0.0 2.6e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain DUF2606 PF10794.4 EKE37972.1 - 0.016 14.6 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) TAFH PF07531.9 EKE37972.1 - 0.049 13.2 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 NHR1 homology to TAF Dockerin_1 PF00404.13 EKE37972.1 - 1.1 9.0 5.6 7.7 6.4 0.6 2.5 2 0 0 2 2 2 0 Dockerin type I repeat WD40 PF00400.27 EKE37973.1 - 3.7e-20 70.9 4.7 2.2e-06 27.3 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 EKE37974.1 - 6.5e-51 172.8 0.0 9.1e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE37974.1 - 1.6e-50 171.6 0.0 2.4e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain VSP PF03302.8 EKE37974.1 - 0.002 16.8 39.0 0.12 11.0 7.9 2.8 1 1 1 2 2 2 2 Giardia variant-specific surface protein MLANA PF14991.1 EKE37974.1 - 0.027 14.4 0.8 0.057 13.4 0.5 1.5 1 0 0 1 1 1 0 Protein melan-A Sigma_reg_N PF13800.1 EKE37974.1 - 0.11 12.4 4.3 0.31 11.1 3.0 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF515 PF04415.7 EKE37974.1 - 0.13 10.4 1.5 0.24 9.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Vpu PF00558.14 EKE37974.1 - 2.1 7.9 4.6 4.1 7.0 3.2 1.4 1 0 0 1 1 1 0 Vpu protein Mon1 PF03164.9 EKE37975.1 - 5.8e-33 114.1 5.2 8.6e-33 113.5 3.6 1.3 1 1 0 1 1 1 1 Trafficking protein Mon1 IBP39 PF11422.3 EKE37975.1 - 0.02 14.3 0.1 0.072 12.5 0.1 1.9 1 0 0 1 1 1 0 Initiator binding protein 39 kDa TIG PF01833.19 EKE37976.1 - 1.6e-11 44.0 1.3 2.6e-11 43.3 0.9 1.4 1 0 0 1 1 1 1 IPT/TIG domain tRNA-synt_1b PF00579.20 EKE37977.1 - 3.6e-09 36.1 1.8 4.8e-08 32.4 0.1 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) SH3_1 PF00018.23 EKE37978.1 - 1.1e-12 47.1 0.0 2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKE37978.1 - 2.8e-10 39.6 0.0 4.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE37978.1 - 3.9e-08 32.6 0.0 1.2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain FCH PF00611.18 EKE37978.1 - 5.8e-05 23.2 0.3 5.8e-05 23.2 0.2 3.3 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain FYRC PF05965.9 EKE37978.1 - 0.0064 16.2 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus SpoIISA_toxin PF14171.1 EKE37978.1 - 0.0066 15.7 3.5 0.0066 15.7 2.4 1.7 2 0 0 2 2 2 1 Toxin SpoIISA, type II toxin-antitoxin system DinI PF06183.8 EKE37978.1 - 0.062 13.3 0.1 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 DinI-like family Bromo_TP PF07524.8 EKE37978.1 - 0.13 12.0 1.1 21 4.9 0.0 3.3 2 1 1 3 3 3 0 Bromodomain associated DUF948 PF06103.6 EKE37978.1 - 0.94 9.3 7.8 1.1 9.1 2.4 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3510 PF12022.3 EKE37978.1 - 1.7 8.7 14.1 3.7 7.6 6.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3510) COG2 PF06148.6 EKE37978.1 - 1.7 8.4 11.3 46 3.8 0.0 3.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MFS_2 PF13347.1 EKE37979.1 - 0.83 7.9 38.3 0.18 10.1 23.7 2.0 1 1 0 1 1 1 0 MFS/sugar transport protein Fip1 PF05182.8 EKE37980.1 - 1.3e-06 27.5 0.3 2.8e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Fip1 motif Peptidase_M43 PF05572.8 EKE37980.1 - 0.044 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A FliL PF03748.9 EKE37980.1 - 0.083 12.8 0.4 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL RasGEF PF00617.14 EKE37983.1 - 2.5e-54 183.8 0.1 8.2e-54 182.1 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE37983.1 - 2.6e-09 37.1 0.1 7.1e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_L32e PF01655.13 EKE37984.1 - 2.1e-43 146.8 0.5 2.5e-43 146.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DUF884 PF05959.6 EKE37984.1 - 0.068 12.4 0.1 0.089 12.0 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Ldh_2 PF02615.9 EKE37986.1 - 4.8e-89 298.3 0.0 6.2e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase VSP PF03302.8 EKE37987.1 - 0.00011 21.0 18.8 0.00011 21.0 13.1 2.2 1 1 1 2 2 2 1 Giardia variant-specific surface protein Marek_A PF02124.10 EKE37987.1 - 0.00028 20.4 0.4 0.00041 19.8 0.3 1.2 1 0 0 1 1 1 1 Marek's disease glycoprotein A Sigma_reg_N PF13800.1 EKE37987.1 - 0.0024 17.8 1.3 0.0024 17.8 0.9 1.6 2 0 0 2 2 2 1 Sigma factor regulator N-terminal LRRC37AB_C PF14914.1 EKE37987.1 - 0.022 14.1 1.0 0.035 13.5 0.7 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain TMEM154 PF15102.1 EKE37987.1 - 0.05 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF3302 PF11742.3 EKE37987.1 - 0.065 13.0 2.0 0.12 12.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) DUF912 PF06024.7 EKE37987.1 - 0.07 13.1 0.1 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4366 PF14283.1 EKE37987.1 - 0.18 11.2 0.3 0.24 10.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3139 PF11337.3 EKE37987.1 - 0.23 11.7 3.0 0.67 10.2 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Baculo_11_kDa PF06143.6 EKE37987.1 - 0.73 9.2 6.1 0.31 10.4 1.8 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Ribosomal_L40e PF01020.12 EKE37988.1 - 1.5e-29 101.3 6.6 1.7e-29 101.1 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L40e family zf-CHY PF05495.7 EKE37988.1 - 0.039 14.1 1.4 0.048 13.8 1.0 1.1 1 0 0 1 1 1 0 CHY zinc finger PAP_central PF04928.12 EKE37989.1 - 6.9e-09 34.8 0.9 3.4e-06 26.0 0.1 3.1 1 1 1 2 2 2 2 Poly(A) polymerase central domain NTP_transf_2 PF01909.18 EKE37989.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EKE37989.1 - 0.0013 16.3 0.0 0.0085 13.6 0.0 2.1 2 1 0 2 2 2 1 Nrap protein Phage_Cox PF10743.4 EKE37989.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Regulatory phage protein cox Sulfotransfer_3 PF13469.1 EKE37990.1 - 8.3e-07 30.0 0.0 1.9e-06 28.9 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE37990.1 - 0.00012 21.4 0.5 0.00061 19.1 0.3 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Thioredoxin_8 PF13905.1 EKE37991.1 - 0.016 15.3 0.6 0.022 14.8 0.3 1.3 1 1 0 1 1 1 0 Thioredoxin-like HALZ PF02183.13 EKE37992.1 - 0.011 15.4 1.7 0.011 15.4 1.2 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper CVNH PF08881.5 EKE37992.1 - 0.066 13.4 0.2 1.1 9.5 0.1 2.9 2 1 0 2 2 2 0 CVNH domain Pkinase PF00069.20 EKE37993.1 - 1.9e-70 236.9 0.0 2.5e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE37993.1 - 6.8e-55 185.9 0.0 9.2e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE37993.1 - 1.3e-06 27.5 0.0 0.00015 20.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras PF00071.17 EKE37995.1 - 1.2e-15 57.2 0.5 1.5e-15 56.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37995.1 - 7.5e-06 26.4 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein CarD_CdnL_TRCF PF02559.11 EKE37995.1 - 0.019 14.9 0.4 0.032 14.2 0.1 1.6 2 0 0 2 2 2 0 CarD-like/TRCF domain RNA_helicase PF00910.17 EKE37995.1 - 0.051 13.7 0.6 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase HTH_7 PF02796.10 EKE37997.1 - 2.2e-06 27.4 1.7 6.4e-06 25.9 1.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.1 EKE37997.1 - 0.00045 20.3 0.0 0.00087 19.4 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn helix HTH_40 PF14493.1 EKE37997.1 - 0.00059 20.0 1.9 0.00076 19.6 0.2 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.7 EKE37997.1 - 0.00085 18.8 0.1 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_32 PF13565.1 EKE37997.1 - 0.003 18.3 0.0 0.0068 17.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 EKE37997.1 - 0.0031 17.1 0.0 0.0094 15.5 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain Arg_repressor PF01316.16 EKE37997.1 - 0.0061 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_28 PF13518.1 EKE37997.1 - 0.0067 16.4 0.5 0.021 14.8 0.4 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EKE37997.1 - 0.011 15.1 0.2 0.027 13.9 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 EKE37997.1 - 0.016 14.7 0.6 0.04 13.4 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF416 PF04222.7 EKE37997.1 - 0.029 13.5 0.3 0.051 12.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF416) Sigma70_ECF PF07638.6 EKE37997.1 - 0.031 13.9 0.1 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 ECF sigma factor HTH_11 PF08279.7 EKE37997.1 - 0.031 13.9 0.2 0.25 11.0 0.0 2.4 3 0 0 3 3 3 0 HTH domain Glyco_trans_4_2 PF13477.1 EKE37997.1 - 0.086 12.6 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like DUF1910 PF08928.5 EKE37997.1 - 0.15 12.1 3.1 0.28 11.2 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) GerE PF00196.14 EKE37997.1 - 0.3 10.4 2.5 0.86 8.9 0.1 2.4 2 1 0 2 2 2 0 Bacterial regulatory proteins, luxR family Phage_antitermQ PF06530.7 EKE37997.1 - 0.5 9.9 2.4 3.7 7.1 0.3 2.2 1 1 1 2 2 2 0 Phage antitermination protein Q HTH_19 PF12844.2 EKE37997.1 - 1 9.4 4.7 13 5.8 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Ras PF00071.17 EKE37998.1 - 8.6e-51 171.5 0.1 1e-50 171.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE37998.1 - 1.2e-15 58.0 0.0 2.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE37998.1 - 6.8e-10 38.4 0.0 7.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE37998.1 - 5.4e-08 32.4 0.1 1.1e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE37998.1 - 0.0058 16.5 0.0 0.0082 16.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Fork_head PF00250.13 EKE37999.1 - 0.028 14.4 0.8 0.052 13.6 0.6 1.4 1 0 0 1 1 1 0 Fork head domain PAT1 PF09770.4 EKE38000.1 - 4.8 5.2 28.0 5.3 5.1 19.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4215 PF13948.1 EKE38001.1 - 0.0021 18.2 8.6 0.0021 18.2 5.9 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4215) TIL PF01826.12 EKE38001.1 - 0.068 13.2 3.9 0.14 12.2 2.7 1.5 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain FixG_C PF11614.3 EKE38001.1 - 0.63 10.1 2.9 3.2 7.8 2.0 1.9 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase WD40 PF00400.27 EKE38002.1 - 6.8e-54 177.9 27.4 9.7e-11 41.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EKE38002.1 - 0.00062 19.5 0.1 0.082 12.6 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EKE38002.1 - 0.004 15.4 0.3 0.025 12.8 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) PQ-loop PF04193.9 EKE38003.1 - 1.6e-16 59.5 11.0 8e-11 41.3 1.5 3.2 3 1 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EKE38003.1 - 0.025 14.4 2.1 0.025 14.4 1.5 2.9 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 EKE38003.1 - 0.066 13.6 0.1 0.066 13.6 0.1 3.4 2 1 1 3 3 3 0 ER lumen protein retaining receptor YwiC PF14256.1 EKE38003.1 - 0.27 11.3 5.3 0.59 10.2 1.2 2.4 1 1 1 2 2 2 0 YwiC-like protein DUF1440 PF07274.7 EKE38003.1 - 0.33 10.9 2.9 0.31 11.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1440) Helicase_C_2 PF13307.1 EKE38006.1 - 4.2e-41 140.6 0.0 7e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1227 PF06777.6 EKE38006.1 - 0.0031 17.2 0.1 0.0081 15.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EKE38007.1 - 0.00069 19.0 0.2 0.00085 18.7 0.1 1.1 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EKE38008.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EKE38008.1 - 0.032 13.5 0.6 0.043 13.1 0.2 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD_2 PF06733.10 EKE38008.1 - 0.041 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 DEAD_2 XRN_N PF03159.13 EKE38009.1 - 8.6e-88 293.7 0.2 2.3e-87 292.3 0.1 1.8 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-C3HC4_3 PF13920.1 EKE38011.1 - 1.7e-05 24.3 16.4 0.0003 20.4 6.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EKE38011.1 - 7.2e-05 22.4 13.5 0.02 14.6 0.2 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EKE38011.1 - 0.0011 18.8 22.1 0.0049 16.6 9.6 2.7 2 1 0 2 2 2 2 Ring finger domain zf-RING_3 PF14369.1 EKE38011.1 - 0.0024 17.8 1.6 0.0024 17.8 1.1 3.1 3 1 0 3 3 2 1 zinc-finger A2L_zn_ribbon PF08792.5 EKE38011.1 - 0.0067 15.8 9.8 0.0092 15.4 2.6 3.0 2 1 0 2 2 2 1 A2L zinc ribbon domain zf-RING_5 PF14634.1 EKE38011.1 - 0.0081 15.8 24.3 0.012 15.2 9.0 2.5 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE38011.1 - 0.018 15.0 23.7 0.29 11.1 2.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE38011.1 - 0.023 14.3 22.0 0.67 9.6 7.3 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 EKE38011.1 - 0.14 11.8 0.3 0.14 11.8 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EKE38011.1 - 0.23 11.2 14.6 0.26 11.1 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbons FYDLN_acid PF09538.5 EKE38011.1 - 0.42 11.2 0.1 0.42 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-rbx1 PF12678.2 EKE38011.1 - 1.4 9.0 12.3 0.13 12.3 4.7 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger PhnA_Zn_Ribbon PF08274.7 EKE38011.1 - 2.2 8.1 12.5 0.16 11.7 0.9 3.2 2 2 0 3 3 3 0 PhnA Zinc-Ribbon CBF PF03914.12 EKE38012.1 - 1.6e-22 79.7 0.0 1.6e-22 79.7 0.0 3.2 3 1 0 3 3 3 1 CBF/Mak21 family DUF4342 PF14242.1 EKE38012.1 - 0.088 12.5 0.4 0.36 10.6 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Arm PF00514.18 EKE38013.1 - 0.022 14.5 0.0 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat XPG_I PF00867.13 EKE38014.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 XPG I-region Pkinase PF00069.20 EKE38015.1 - 1.4e-61 207.9 1.4 8.7e-56 188.9 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38015.1 - 5.9e-32 110.7 0.0 3.1e-31 108.3 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EKE38015.1 - 0.097 12.3 0.0 0.84 9.3 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EKE38016.1 - 8.9e-47 159.4 0.1 1.8e-46 158.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38016.1 - 5.5e-41 140.3 0.0 1e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.8 EKE38016.1 - 0.0021 16.7 114.4 0.015 13.9 24.6 4.7 1 1 2 3 3 3 2 Giardia variant-specific surface protein UPF0020 PF01170.13 EKE38018.1 - 4e-12 46.0 0.0 6.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EKE38018.1 - 8.3e-11 41.9 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EKE38018.1 - 0.00028 20.4 0.1 0.037 13.5 0.0 2.4 2 0 0 2 2 2 2 DNA methylase Methyltransf_15 PF09445.5 EKE38018.1 - 0.068 12.7 0.0 0.29 10.6 0.0 2.0 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Thioredoxin PF00085.15 EKE38019.1 - 3.4e-18 65.2 0.3 6.3e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EKE38019.1 - 2.6e-07 31.1 0.5 3.9e-06 27.4 0.0 2.7 2 1 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Calsequestrin PF01216.12 EKE38019.1 - 0.037 12.8 0.5 0.074 11.8 0.4 1.5 1 0 0 1 1 1 0 Calsequestrin Thioredoxin_2 PF13098.1 EKE38019.1 - 0.075 13.2 0.3 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain AhpC-TSA PF00578.16 EKE38019.1 - 0.19 11.4 1.2 1 9.0 0.1 2.2 2 0 0 2 2 2 0 AhpC/TSA family BTB_2 PF02214.17 EKE38021.1 - 0.00019 21.5 0.4 0.00069 19.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain SPRY PF00622.23 EKE38021.1 - 0.003 17.6 0.1 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 SPRY domain nsp7 PF08716.5 EKE38021.1 - 0.05 13.9 0.4 0.15 12.4 0.3 1.8 1 0 0 1 1 1 0 nsp7 replicase DUF641 PF04859.7 EKE38021.1 - 9.1 6.0 12.9 9.8 5.9 3.6 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) LRR_4 PF12799.2 EKE38022.1 - 3e-06 26.7 31.3 0.038 13.6 1.1 7.4 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) CART PF06373.6 EKE38022.1 - 0.04 13.8 0.1 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) LpxD PF04613.9 EKE38022.1 - 0.075 12.5 0.3 0.64 9.5 0.0 2.3 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD LIM PF00412.17 EKE38023.1 - 5.4e-07 29.5 10.1 1.1e-06 28.6 7.0 1.5 1 0 0 1 1 1 1 LIM domain Ribosomal_L11 PF00298.14 EKE38023.1 - 0.025 14.7 0.1 6.5 6.9 0.0 2.4 1 1 1 2 2 2 0 Ribosomal protein L11, RNA binding domain Prok-RING_1 PF14446.1 EKE38023.1 - 0.16 11.7 7.2 0.38 10.5 5.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Reprolysin_3 PF13582.1 EKE38023.1 - 0.2 12.1 4.1 1.9 9.0 0.7 2.2 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like RRM_1 PF00076.17 EKE38024.1 - 1.7e-06 27.5 0.0 3.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE38024.1 - 0.00023 21.0 0.0 0.00049 20.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EKE38026.1 - 1.9e-28 99.0 0.0 2.7e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ELK PF03789.8 EKE38026.1 - 0.074 12.8 0.7 0.3 10.9 0.5 2.1 1 0 0 1 1 1 0 ELK domain Peptidase_C48 PF02902.14 EKE38027.1 - 1e-20 74.3 1.7 1.9e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PH_10 PF15411.1 EKE38027.1 - 0.22 11.7 6.6 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain START PF01852.14 EKE38028.1 - 4.1e-22 78.5 1.0 5.8e-22 78.0 0.7 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE38028.1 - 3.4e-05 23.5 1.6 0.00021 20.9 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) IPI_T4 PF11634.3 EKE38028.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 IPK PF03770.11 EKE38029.1 - 1.1e-35 123.0 1.0 1.5e-35 122.6 0.7 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Lung_7-TM_R PF06814.8 EKE38030.1 - 1.2e-12 47.4 17.2 1.6e-12 46.9 11.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Oxidored_q5_N PF01059.12 EKE38030.1 - 3.6 7.5 10.9 0.3 10.9 3.2 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus 14-3-3 PF00244.15 EKE38032.1 - 5.1e-98 326.8 9.4 5.9e-98 326.6 6.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EKE38032.1 - 0.0011 18.8 1.3 0.14 12.0 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF837 PF05769.6 EKE38032.1 - 0.041 13.4 2.9 0.12 11.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF837) DUF885 PF05960.6 EKE38032.1 - 0.14 11.3 2.0 0.18 10.9 1.4 1.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF3461 PF11944.3 EKE38032.1 - 0.2 11.4 3.4 0.25 11.1 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3461) TPR_8 PF13181.1 EKE38032.1 - 2.6 8.0 6.6 22 5.1 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Arm PF00514.18 EKE38033.1 - 1.5e-07 30.9 0.2 0.47 10.3 0.0 6.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat ACDC PF14733.1 EKE38033.1 - 0.067 13.3 0.4 0.067 13.3 0.3 3.1 3 0 0 3 3 3 0 AP2-coincident C-terminal SNARE PF05739.14 EKE38034.1 - 5.1e-06 26.0 2.5 0.018 14.7 0.1 2.1 1 1 1 2 2 2 2 SNARE domain Prominin PF05478.6 EKE38034.1 - 0.0085 13.6 0.7 0.0094 13.5 0.5 1.1 1 0 0 1 1 1 1 Prominin UPF0122 PF04297.9 EKE38034.1 - 0.03 14.3 0.2 0.048 13.6 0.1 1.4 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like EzrA PF06160.7 EKE38034.1 - 0.031 12.4 0.7 0.038 12.1 0.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sec20 PF03908.8 EKE38034.1 - 0.04 13.6 0.2 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Sec20 ING PF12998.2 EKE38034.1 - 0.078 13.2 0.3 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ANTH PF07651.11 EKE38035.1 - 8.7e-05 21.3 0.1 8.7e-05 21.3 0.1 2.7 2 1 0 3 3 3 1 ANTH domain ENTH PF01417.15 EKE38035.1 - 0.00023 21.0 2.8 0.0007 19.4 1.9 1.8 1 0 0 1 1 1 1 ENTH domain Corona_nucleoca PF00937.13 EKE38035.1 - 0.13 11.2 5.8 0.18 10.7 4.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein zf-DHHC PF01529.15 EKE38036.1 - 7.6e-24 84.0 20.5 7.6e-24 84.0 14.2 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase PIG-Y PF15159.1 EKE38036.1 - 0.13 12.5 0.4 0.13 12.5 0.3 3.5 3 1 1 4 4 4 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Wzy_C PF04932.10 EKE38036.1 - 0.69 9.6 11.4 0.16 11.7 2.6 2.2 2 0 0 2 2 2 0 O-Antigen ligase DUF872 PF05915.7 EKE38036.1 - 0.92 9.3 6.9 2.2 8.1 0.6 2.6 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Laminin_II PF06009.7 EKE38037.1 - 0.034 13.8 26.3 0.27 11.0 0.0 4.6 2 1 1 4 4 4 0 Laminin Domain II Reo_sigmaC PF04582.7 EKE38037.1 - 0.044 12.9 5.9 0.24 10.5 1.6 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein MbeD_MobD PF04899.7 EKE38037.1 - 0.062 13.1 14.9 6.4 6.7 2.3 4.6 3 1 0 3 3 3 0 MbeD/MobD like DUF2959 PF11172.3 EKE38037.1 - 0.15 11.8 20.2 0.46 10.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) NPV_P10 PF05531.7 EKE38037.1 - 0.23 11.7 21.8 0.57 10.4 0.7 4.8 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EKE38037.1 - 0.51 10.1 29.5 0.25 11.1 3.3 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 EKE38037.1 - 1.1 9.6 7.4 0.12 12.7 0.8 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Tweety PF04906.8 EKE38037.1 - 4 5.7 10.6 2.4 6.4 4.6 2.2 2 0 0 2 2 2 0 Tweety Cep57_CLD_2 PF14197.1 EKE38037.1 - 4.1 7.4 35.5 0.065 13.1 4.8 4.4 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 Pkinase PF00069.20 EKE38038.1 - 4.1e-59 199.8 0.0 6.5e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38038.1 - 5.9e-38 130.4 0.0 8.4e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EKE38038.1 - 0.031 13.8 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EKE38038.1 - 0.044 13.5 0.0 0.14 11.8 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EKE38038.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRKCSH-like PF12999.2 EKE38040.1 - 9.1e-28 97.0 14.9 9.1e-28 97.0 10.3 2.9 1 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EKE38040.1 - 3.4e-11 42.8 6.8 3.4e-11 42.8 4.7 2.9 2 2 2 4 4 4 1 Glucosidase II beta subunit-like protein ETRAMP PF09716.5 EKE38040.1 - 0.0012 18.7 0.0 2.1 8.3 0.0 4.0 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Ldl_recept_a PF00057.13 EKE38040.1 - 0.024 14.5 18.1 0.24 11.3 2.0 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A TraB PF01963.12 EKE38040.1 - 3.9 6.8 10.2 0.028 13.8 0.6 2.0 2 0 0 2 2 2 0 TraB family PNP_UDP_1 PF01048.15 EKE38041.1 - 7.4e-07 28.3 0.0 9e-07 28.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.15 EKE38042.1 - 1.6e-16 60.0 0.2 1.8e-16 59.8 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3595 PF12166.3 EKE38043.1 - 2.7e-79 266.9 7.3 2.7e-79 266.9 5.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3595) Glyco_hydro_7 PF00840.15 EKE38043.1 - 0.073 11.4 0.3 0.11 10.7 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 NLPC_P60 PF00877.14 EKE38043.1 - 0.14 11.9 0.5 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 NlpC/P60 family Inhibitor_I53 PF11714.3 EKE38043.1 - 0.35 10.8 0.4 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Nse4_C PF08743.5 EKE38045.1 - 6.3e-23 80.6 0.7 1.1e-22 79.7 0.5 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Syntaxin PF00804.20 EKE38048.1 - 0.0035 17.4 4.7 0.0048 17.0 3.3 1.3 1 0 0 1 1 1 1 Syntaxin AAA_5 PF07728.9 EKE38048.1 - 0.015 15.0 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) EBA-175_VI PF11556.3 EKE38048.1 - 1.7 8.8 8.1 1.3 9.1 2.3 2.4 2 1 0 2 2 2 0 Erythrocyte binding antigen 175 TLD PF07534.11 EKE38049.1 - 0.00051 20.0 1.0 0.00082 19.3 0.7 1.4 1 0 0 1 1 1 1 TLD DUF1189 PF06691.6 EKE38049.1 - 0.019 14.2 1.2 0.031 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) ATG16 PF08614.6 EKE38049.1 - 0.043 13.6 6.4 0.061 13.1 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-CpG_bind_C PF12269.3 EKE38049.1 - 0.21 11.0 2.0 0.33 10.3 1.4 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Laminin_II PF06009.7 EKE38049.1 - 0.26 11.0 5.5 0.36 10.5 3.8 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF2203 PF09969.4 EKE38049.1 - 0.8 9.9 3.5 1.4 9.1 2.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Bap31 PF05529.7 EKE38049.1 - 3.5 7.0 7.6 5.5 6.3 5.3 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like XhlA PF10779.4 EKE38049.1 - 7.5 6.5 12.3 0.15 11.9 2.3 2.5 2 1 1 3 3 3 0 Haemolysin XhlA Lant_dehyd_N PF04737.8 EKE38050.1 - 0.093 12.7 0.1 12 5.9 0.0 2.1 2 0 0 2 2 2 0 Lantibiotic dehydratase, N terminus Stk19 PF10494.4 EKE38051.1 - 1.6 8.0 6.6 1.9 7.8 3.3 1.8 1 1 1 2 2 2 0 Serine-threonine protein kinase 19 NHL PF01436.16 EKE38052.1 - 2.5e-09 36.6 8.3 0.46 10.5 0.2 6.5 5 2 0 5 5 5 3 NHL repeat zf-B_box PF00643.19 EKE38052.1 - 5.5e-07 29.3 7.6 5.5e-07 29.3 5.3 4.6 3 1 1 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.1 EKE38052.1 - 7.8e-07 28.7 3.5 7.8e-07 28.7 2.5 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EKE38052.1 - 0.00027 20.6 10.7 0.00027 20.6 7.4 3.3 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EKE38052.1 - 0.0016 18.1 11.1 0.0016 18.1 7.7 3.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EKE38052.1 - 0.0026 17.3 11.3 0.0026 17.3 7.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Cas_Cas1 PF01867.11 EKE38053.1 - 0.0073 15.4 2.2 0.008 15.2 1.5 1.2 1 0 0 1 1 1 1 CRISPR associated protein Cas1 DUF1690 PF07956.6 EKE38053.1 - 0.016 15.1 5.0 0.016 15.1 3.4 1.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF382 PF04037.8 EKE38053.1 - 0.025 14.3 1.6 0.032 14.0 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF382) DUF972 PF06156.8 EKE38053.1 - 8.4 6.7 8.7 6.1 7.2 4.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PP2C PF00481.16 EKE38054.1 - 2.3e-28 99.3 0.3 4.4e-28 98.3 0.2 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE38054.1 - 3.5e-08 33.0 0.0 6.6e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C NAC PF01849.13 EKE38055.1 - 0.00057 19.3 0.2 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 NAC domain Ribosomal_L6e PF01159.14 EKE38055.1 - 4.5 7.5 7.4 0.97 9.7 2.3 1.8 2 0 0 2 2 2 0 Ribosomal protein L6e Toxin_56 PF15534.1 EKE38055.1 - 4.8 7.7 7.2 1.3 9.5 0.8 2.6 3 0 0 3 3 3 0 Putative toxin 56 Nol1_Nop2_Fmu PF01189.12 EKE38056.1 - 3.9e-92 308.6 0.0 6.7e-92 307.8 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EKE38056.1 - 3.4e-06 26.7 0.1 3.4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EKE38056.1 - 0.00052 20.0 0.0 0.00052 20.0 0.0 2.5 2 1 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EKE38056.1 - 0.0066 15.5 0.0 0.019 14.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EKE38056.1 - 0.015 15.8 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EKE38056.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2203 PF09969.4 EKE38056.1 - 3.4 7.8 10.9 0.2 11.9 0.4 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) BP28CT PF08146.7 EKE38057.1 - 1.6e-11 44.1 4.5 3.4e-11 43.0 0.3 3.8 3 0 0 3 3 3 1 BP28CT (NUC211) domain HEAT_2 PF13646.1 EKE38057.1 - 0.033 14.4 0.1 0.27 11.5 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EKE38057.1 - 0.04 13.9 2.3 10 6.4 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EKE38057.1 - 0.79 10.2 0.8 69 4.1 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat DUF3201 PF11447.3 EKE38058.1 - 0.057 12.8 0.4 0.097 12.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3201) HsdM_N PF12161.3 EKE38058.1 - 0.058 13.8 0.2 0.07 13.5 0.1 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain FtsK_SpoIIIE PF01580.13 EKE38059.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-C2H2_4 PF13894.1 EKE38061.1 - 7.6e-05 22.7 27.8 0.31 11.4 1.3 6.9 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 EKE38061.1 - 7.7e-05 22.2 11.0 7.7e-05 22.2 7.6 3.6 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 EKE38061.1 - 0.033 14.5 31.3 0.94 9.9 1.6 7.1 6 1 0 6 6 6 0 Zinc finger, C2H2 type Secretin_N_2 PF07655.8 EKE38061.1 - 0.13 12.6 1.9 0.27 11.6 1.3 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain zf-C2H2_2 PF12756.2 EKE38061.1 - 0.26 11.3 26.9 0.26 11.3 5.2 4.7 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Rap_GAP PF02145.10 EKE38063.1 - 4.9e-40 136.9 1.9 1.5e-39 135.2 1.3 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Ank_2 PF12796.2 EKE38063.1 - 4.2e-29 100.7 4.5 1.6e-12 47.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE38063.1 - 2.8e-28 96.2 0.2 3.2e-05 23.5 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EKE38063.1 - 3.7e-25 87.8 0.2 2.1e-08 34.4 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE38063.1 - 2.4e-23 79.8 1.4 0.0011 19.0 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EKE38063.1 - 1.9e-17 62.8 0.6 1.8e-05 24.8 0.0 3.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Syntaxin PF00804.20 EKE38064.1 - 0.00057 20.0 2.8 0.00074 19.6 2.0 1.2 1 0 0 1 1 1 1 Syntaxin Phage_GPO PF05929.6 EKE38064.1 - 0.0057 15.9 0.3 0.0073 15.6 0.2 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase HAUS-augmin3 PF14932.1 EKE38064.1 - 0.049 12.8 3.2 0.058 12.5 2.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mt_ATP-synt_D PF05873.7 EKE38064.1 - 0.11 12.1 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) MotB_plug PF13677.1 EKE38064.1 - 0.16 11.3 0.7 0.38 10.0 0.5 1.8 1 1 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Med30 PF11315.3 EKE38064.1 - 0.19 11.8 3.3 0.42 10.7 2.3 1.6 1 1 0 1 1 1 0 Mediator complex subunit 30 COG2 PF06148.6 EKE38064.1 - 0.44 10.4 4.0 1.4 8.7 2.9 1.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 EKE38064.1 - 0.76 10.0 3.4 26 5.1 2.3 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.3 EKE38064.1 - 1 9.1 5.0 3.4 7.4 0.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DASH_Dad2 PF08654.5 EKE38064.1 - 1.1 9.3 5.9 0.6 10.1 1.4 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad2 HTH_3 PF01381.17 EKE38065.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Cir_N PF10197.4 EKE38067.1 - 0.0029 17.5 8.6 0.0029 17.5 6.0 3.1 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR LuxC PF05893.9 EKE38067.1 - 0.075 11.7 0.3 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF123 PF01986.11 EKE38067.1 - 0.35 11.0 1.4 0.43 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF123 PAP_central PF04928.12 EKE38067.1 - 1 8.1 4.1 1.2 7.9 2.8 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain FliS PF02561.9 EKE38067.1 - 2.2 8.1 6.6 1 9.2 3.1 1.5 1 1 1 2 2 2 0 Flagellar protein FliS GST_C PF00043.20 EKE38067.1 - 5.6 7.0 8.0 1.1 9.2 0.6 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Rap_GAP PF02145.10 EKE38068.1 - 2e-47 161.0 1.3 2e-47 161.0 0.9 2.5 3 0 0 3 3 3 1 Rap/ran-GAP C2 PF00168.25 EKE38068.1 - 0.0001 22.0 2.6 0.00067 19.4 0.0 3.0 3 0 0 3 3 3 1 C2 domain FBA_3 PF08268.7 EKE38068.1 - 0.034 13.8 2.4 0.11 12.2 1.7 1.9 1 0 0 1 1 1 0 F-box associated domain ATP_bind_3 PF01171.15 EKE38069.1 - 2e-18 66.5 0.0 3.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.14 EKE38069.1 - 0.018 14.8 0.0 0.052 13.3 0.0 1.8 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PHF5 PF03660.9 EKE38069.1 - 0.029 14.4 0.7 0.029 14.4 0.5 2.8 3 0 0 3 3 3 0 PHF5-like protein tRNA_Me_trans PF03054.11 EKE38069.1 - 0.03 12.8 0.0 0.055 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.12 EKE38069.1 - 0.049 12.5 0.0 0.079 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD synthase NosL PF05573.7 EKE38069.1 - 1 9.0 3.9 0.43 10.2 0.7 1.8 1 1 1 2 2 2 0 NosL zf-UBR PF02207.15 EKE38069.1 - 7.1 6.4 13.4 1.1 9.0 1.4 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Apyrase PF06079.6 EKE38072.1 - 3.8e-74 249.4 8.3 4.7e-74 249.1 5.8 1.0 1 0 0 1 1 1 1 Apyrase Tetraspannin PF00335.15 EKE38073.1 - 8.4e-07 28.4 23.0 1.9e-06 27.3 16.0 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF981 PF06168.6 EKE38073.1 - 0.00012 21.8 0.1 0.00022 21.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF981) TauE PF01925.14 EKE38073.1 - 0.00026 20.5 1.2 0.00026 20.5 0.8 1.5 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE DUF2306 PF10067.4 EKE38073.1 - 0.023 14.8 0.3 0.023 14.8 0.2 2.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) CD20 PF04103.10 EKE38073.1 - 0.025 14.5 14.2 0.036 14.0 9.8 1.2 1 0 0 1 1 1 0 CD20-like family DUF4149 PF13664.1 EKE38073.1 - 0.052 13.6 0.5 0.052 13.6 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF3357 PF11837.3 EKE38073.1 - 0.16 11.8 0.5 17 5.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF3278 PF11683.3 EKE38073.1 - 0.22 11.5 9.0 1.2 9.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) DUF3671 PF12420.3 EKE38073.1 - 0.69 9.9 18.2 0.69 9.9 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function NfeD PF01957.13 EKE38073.1 - 0.83 9.7 6.2 3.3 7.8 3.4 2.3 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding MARVEL PF01284.18 EKE38073.1 - 0.85 9.4 11.2 3.4 7.4 0.7 2.6 1 1 0 2 2 2 0 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EKE38073.1 - 2.5 7.7 18.0 0.19 11.3 6.7 2.4 2 1 1 3 3 3 0 7TM diverse intracellular signalling VIT1 PF01988.14 EKE38073.1 - 2.5 7.5 12.2 0.027 13.9 3.3 1.5 2 0 0 2 2 2 0 VIT family Afaf PF15339.1 EKE38073.1 - 9.4 5.7 7.7 4.4 6.8 0.2 2.7 3 0 0 3 3 3 0 Acrosome formation-associated factor RasGEF PF00617.14 EKE38074.1 - 3.3e-19 69.3 0.3 8.5e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain Abhydrolase_6 PF12697.2 EKE38075.1 - 4.3e-06 26.7 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE38075.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKE38075.1 - 0.00017 21.4 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKE38075.1 - 0.017 14.5 0.0 0.8 9.0 0.0 2.8 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1057 PF06342.7 EKE38075.1 - 0.02 13.7 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Myotub-related PF06602.9 EKE38076.1 - 3.6e-100 335.1 0.1 7.2e-100 334.1 0.1 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PX PF00787.19 EKE38076.1 - 0.086 12.6 3.7 0.068 12.9 0.8 2.2 2 0 0 2 2 2 0 PX domain Y_phosphatase3 PF13350.1 EKE38076.1 - 0.12 12.5 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2892 PF11127.3 EKE38077.1 - 0.084 12.7 0.1 0.084 12.7 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) PRA1 PF03208.14 EKE38077.1 - 0.51 9.6 12.8 0.43 9.9 6.5 1.9 2 0 0 2 2 2 0 PRA1 family protein UPF0139 PF03669.8 EKE38077.1 - 0.69 9.4 2.5 8.1 6.0 1.8 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) DUF3488 PF11992.3 EKE38077.1 - 3.5 6.1 7.8 4.1 5.9 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF2973 PF11189.3 EKE38077.1 - 6.5 6.6 5.7 10 5.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) Renin_r PF07850.9 EKE38077.1 - 6.6 7.1 11.0 0.25 11.7 0.4 2.6 3 0 0 3 3 3 0 Renin receptor-like protein PUA PF01472.15 EKE38079.1 - 2.4e-14 52.7 0.4 3.5e-14 52.2 0.3 1.3 1 0 0 1 1 1 1 PUA domain Cullin PF00888.17 EKE38080.1 - 1.8e-20 73.0 42.0 1.8e-20 73.0 29.1 1.8 2 1 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EKE38080.1 - 1.4e-15 56.8 4.6 1.4e-15 56.8 3.2 3.9 4 1 1 5 5 5 1 Cullin protein neddylation domain zf-CHC2 PF01807.15 EKE38080.1 - 0.72 9.4 8.6 1.6 8.3 0.1 3.7 4 0 0 4 4 4 0 CHC2 zinc finger Cation_ATPase_C PF00689.16 EKE38081.1 - 1.7e-31 109.1 2.9 2.1e-31 108.8 2.0 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus C2 PF00168.25 EKE38083.1 - 3.3e-18 65.3 0.3 1.7e-15 56.6 0.1 2.8 3 0 0 3 3 3 2 C2 domain SGT1 PF07093.6 EKE38084.1 - 6e-17 61.2 0.4 6e-17 61.2 0.3 3.1 1 1 1 3 3 3 2 SGT1 protein DUF3991 PF13154.1 EKE38084.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) Ribosomal_S25 PF03297.10 EKE38086.1 - 1.1e-33 115.4 4.9 1.1e-33 115.4 3.4 1.8 1 1 1 2 2 2 1 S25 ribosomal protein ArfGap PF01412.13 EKE38087.1 - 2.2e-34 117.7 0.7 2.2e-34 117.7 0.5 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Phage_GP20 PF06810.6 EKE38088.1 - 0.00047 19.6 7.7 0.015 14.7 1.4 2.1 1 1 1 2 2 2 2 Phage minor structural protein GP20 CENP-F_N PF10481.4 EKE38088.1 - 0.0098 15.2 1.0 0.0098 15.2 0.7 1.2 1 0 0 1 1 1 1 Cenp-F N-terminal domain End3 PF12761.2 EKE38088.1 - 0.012 15.3 1.6 0.018 14.6 1.1 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 CALCOCO1 PF07888.6 EKE38088.1 - 0.016 13.5 4.5 0.018 13.3 3.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CorA PF01544.13 EKE38088.1 - 0.041 12.9 2.5 0.3 10.0 0.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein WXG100 PF06013.7 EKE38088.1 - 0.048 13.6 0.3 0.079 12.9 0.2 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG She9_MDM33 PF05546.6 EKE38088.1 - 0.088 12.3 1.3 0.09 12.3 0.9 1.3 1 1 0 1 1 1 0 She9 / Mdm33 family DUF4549 PF15082.1 EKE38088.1 - 0.15 11.7 1.2 0.16 11.6 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) DUF1539 PF07560.6 EKE38088.1 - 0.23 11.3 3.7 2.1 8.2 0.0 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) Prefoldin_2 PF01920.15 EKE38088.1 - 0.3 10.8 5.0 0.11 12.2 1.7 1.6 2 0 0 2 2 2 0 Prefoldin subunit PhaP_Bmeg PF09602.5 EKE38088.1 - 0.33 10.7 5.1 0.3 10.8 0.9 2.0 1 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FlaC_arch PF05377.6 EKE38088.1 - 0.35 10.7 3.0 0.48 10.3 0.3 2.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) PspA_IM30 PF04012.7 EKE38088.1 - 0.47 9.7 3.6 0.32 10.3 1.2 1.6 1 1 0 1 1 1 0 PspA/IM30 family FlxA PF14282.1 EKE38088.1 - 0.62 10.0 5.1 0.47 10.4 2.2 1.8 2 0 0 2 2 2 0 FlxA-like protein TPR_MLP1_2 PF07926.7 EKE38088.1 - 3.8 7.2 8.0 9.9 5.9 5.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ank_2 PF12796.2 EKE38089.1 - 7e-21 74.3 3.5 4.8e-11 42.8 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE38089.1 - 3.9e-15 55.5 0.0 5.3e-07 29.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RabGAP-TBC PF00566.13 EKE38089.1 - 7.3e-15 55.0 2.2 7.3e-15 55.0 1.6 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Ank PF00023.25 EKE38089.1 - 5.5e-14 51.1 0.0 3.9e-05 23.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EKE38089.1 - 1.4e-13 50.9 0.8 0.0018 18.7 0.1 4.5 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE38089.1 - 2.1e-09 36.7 0.4 0.00083 19.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat RNA_pol_Rpb4 PF03874.11 EKE38089.1 - 0.028 14.4 1.1 0.71 9.9 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase Rpb4 BRCT PF00533.21 EKE38090.1 - 2.1e-10 40.5 7.3 5.2e-06 26.5 0.1 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain MIP-T3 PF10243.4 EKE38090.1 - 0.21 10.0 62.8 0.3 9.4 43.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 EKE38090.1 - 0.71 9.0 57.6 1 8.5 39.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PLRV_ORF5 PF01690.12 EKE38090.1 - 0.73 8.9 27.6 0.91 8.6 19.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Borrelia_P83 PF05262.6 EKE38090.1 - 0.92 7.6 41.5 1.4 7.1 28.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein AvrE PF11725.3 EKE38090.1 - 6 3.7 30.3 7.3 3.4 21.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor SOBP PF15279.1 EKE38090.1 - 6.5 7.0 19.3 10 6.4 13.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Metallophos PF00149.23 EKE38091.1 - 1.7e-29 102.6 0.1 2.6e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Isochorismatase PF00857.15 EKE38092.1 - 0.11 12.4 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Isochorismatase family Ribosomal_L27e PF01777.13 EKE38093.1 - 8.4e-21 73.8 4.2 1.5e-20 73.0 2.9 1.4 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EKE38093.1 - 4.4e-06 26.2 3.7 6.2e-06 25.7 1.3 2.2 2 0 0 2 2 2 1 KOW motif DUF3728 PF12528.3 EKE38093.1 - 0.077 13.4 0.1 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Prepilin peptidase dependent protein C (DUF3728) Mon1 PF03164.9 EKE38094.1 - 1.8e-52 178.3 1.6 2.3e-52 178.0 1.1 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 RhoGEF PF00621.15 EKE38095.1 - 3.2e-13 49.9 4.6 3.2e-13 49.9 3.2 2.5 2 0 0 2 2 2 1 RhoGEF domain RGS PF00615.14 EKE38095.1 - 3.3e-11 43.3 7.2 3.5e-11 43.2 3.2 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain Ras PF00071.17 EKE38096.1 - 3.6e-43 146.7 0.0 4.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38096.1 - 4.4e-17 62.6 0.1 7.9e-17 61.8 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EKE38096.1 - 9.5e-14 51.0 0.0 1.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE38096.1 - 1.1e-06 27.9 0.0 1.3e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE38096.1 - 0.00023 21.0 0.0 0.00051 19.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE38096.1 - 0.00026 20.2 0.3 0.00057 19.1 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE38096.1 - 0.00068 19.1 0.0 0.0095 15.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EKE38096.1 - 0.0012 19.0 0.0 0.0019 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EKE38096.1 - 0.0021 17.6 0.2 0.14 11.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EKE38096.1 - 0.0054 15.4 3.9 0.021 13.5 0.1 2.5 2 1 1 3 3 3 1 G-protein alpha subunit AAA_14 PF13173.1 EKE38096.1 - 0.012 15.5 0.2 0.33 10.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EKE38096.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EKE38096.1 - 0.069 12.6 0.0 0.13 11.7 0.1 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 EKE38096.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EKE38096.1 - 0.087 12.3 0.1 0.37 10.2 0.1 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YTH PF04146.10 EKE38096.1 - 0.1 12.2 0.1 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 YT521-B-like domain AAA_24 PF13479.1 EKE38096.1 - 0.12 11.9 0.4 0.24 10.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain Ribosomal_L30 PF00327.15 EKE38097.1 - 4.9e-21 74.0 1.8 1.1e-20 72.9 1.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EKE38097.1 - 0.06 13.3 1.2 0.14 12.2 0.8 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain AAA PF00004.24 EKE38098.1 - 1.4e-48 164.4 1.1 3.1e-42 143.9 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EKE38098.1 - 8.5e-10 38.6 5.1 0.00051 19.9 0.0 4.0 2 1 2 4 4 4 2 AAA domain AAA_16 PF13191.1 EKE38098.1 - 2.8e-09 37.2 0.0 0.00026 21.0 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EKE38098.1 - 5.1e-09 35.9 0.0 0.00029 20.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EKE38098.1 - 7.5e-09 34.8 0.0 4.6e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EKE38098.1 - 1.2e-08 34.3 0.0 1.9e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKE38098.1 - 1.3e-08 35.7 0.1 1.4e-05 25.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EKE38098.1 - 1.6e-07 31.4 0.0 6.3e-05 22.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EKE38098.1 - 3.6e-07 30.3 0.2 0.0011 19.1 0.0 3.4 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EKE38098.1 - 5.2e-07 29.2 0.0 0.0004 19.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 EKE38098.1 - 1.4e-06 28.6 0.0 0.081 13.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Arch_ATPase PF01637.13 EKE38098.1 - 9.6e-06 25.4 3.0 0.0058 16.3 0.0 3.7 2 1 1 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 EKE38098.1 - 2e-05 23.5 0.0 0.0002 20.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 EKE38098.1 - 9.1e-05 21.7 0.0 0.00051 19.2 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EKE38098.1 - 0.00012 21.7 0.0 0.002 17.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EKE38098.1 - 0.00013 22.1 0.0 0.033 14.3 0.0 3.1 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.7 EKE38098.1 - 0.00013 21.6 0.0 0.83 9.2 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_33 PF13671.1 EKE38098.1 - 0.00013 21.8 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EKE38098.1 - 0.00014 21.5 0.0 0.051 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKE38098.1 - 0.00019 20.3 0.2 0.028 13.2 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain NTPase_1 PF03266.10 EKE38098.1 - 0.00045 19.9 0.3 2.6 7.7 0.0 3.5 2 1 1 3 3 3 2 NTPase AAA_25 PF13481.1 EKE38098.1 - 0.00077 18.9 0.1 0.31 10.4 0.1 2.5 2 1 1 3 3 2 1 AAA domain DUF258 PF03193.11 EKE38098.1 - 0.0008 18.6 0.3 0.8 8.8 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_3 PF07726.6 EKE38098.1 - 0.00081 19.0 0.0 0.36 10.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKE38098.1 - 0.00091 18.7 0.0 0.025 14.0 0.0 2.6 2 1 1 3 3 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EKE38098.1 - 0.0012 18.7 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKE38098.1 - 0.0033 16.9 0.0 11 5.3 0.0 3.4 2 1 1 3 3 3 0 AAA-like domain AAA_11 PF13086.1 EKE38098.1 - 0.0033 17.0 0.0 0.28 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EKE38098.1 - 0.0038 16.4 0.0 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.1 EKE38098.1 - 0.0057 16.9 0.2 0.033 14.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain KaiC PF06745.8 EKE38098.1 - 0.016 14.3 0.1 0.63 9.1 0.0 2.8 1 1 1 2 2 2 0 KaiC Bac_DnaA PF00308.13 EKE38098.1 - 0.021 14.4 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein SKI PF01202.17 EKE38098.1 - 0.023 14.5 0.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.1 EKE38098.1 - 0.024 14.1 1.0 5.8 6.5 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SE PF00437.15 EKE38098.1 - 0.027 13.3 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.10 EKE38098.1 - 0.034 13.9 1.0 0.15 11.9 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EKE38098.1 - 0.053 12.6 0.0 0.56 9.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.1 EKE38098.1 - 0.063 13.3 0.0 0.49 10.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EKE38098.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 2 0 0 2 2 1 0 AAA domain HEAT PF02985.17 EKE38099.1 - 5.7e-16 57.0 9.1 0.012 15.6 0.0 9.7 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.1 EKE38099.1 - 1.8e-09 37.7 0.0 0.0055 16.9 0.0 5.9 3 3 2 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EKE38099.1 - 5.1e-08 33.1 0.4 11 6.6 0.1 7.4 8 0 0 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EKE38099.1 - 3.9e-06 27.1 4.6 0.0038 17.5 0.1 4.7 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region GCR1_C PF12550.3 EKE38099.1 - 0.11 12.3 0.3 0.4 10.5 0.2 2.0 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Cullin_binding PF03556.10 EKE38100.1 - 6.2e-19 68.2 1.8 1.3e-18 67.2 1.3 1.5 1 0 0 1 1 1 1 Cullin binding Ndc1_Nup PF09531.5 EKE38100.1 - 0.71 8.2 7.5 0.85 7.9 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4306 PF14154.1 EKE38101.1 - 0.095 12.6 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) PH PF00169.24 EKE38101.1 - 0.17 12.0 1.3 0.53 10.5 0.9 1.8 1 1 0 1 1 1 0 PH domain PIG-H PF10181.4 EKE38102.1 - 9.1e-05 22.0 0.9 9.1e-05 22.0 0.6 1.7 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component AA_permease_C PF13906.1 EKE38102.1 - 0.9 9.4 4.6 2.4 8.0 3.1 1.8 1 1 1 2 2 2 0 C-terminus of AA_permease zf-CCCH PF00642.19 EKE38103.1 - 2.4e-10 39.8 3.3 2.4e-10 39.8 2.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EKE38103.1 - 3.4e-07 29.8 12.1 3.4e-07 29.8 8.4 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKE38103.1 - 8.1e-05 22.2 12.9 0.00028 20.4 8.9 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE38103.1 - 0.041 13.7 10.5 0.041 13.7 7.3 2.0 2 1 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 EKE38103.1 - 0.043 13.5 6.3 0.32 10.7 4.4 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EKE38103.1 - 0.074 13.0 14.1 0.21 11.6 9.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_6 PF03414.8 EKE38103.1 - 0.092 11.1 1.0 0.14 10.6 0.7 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 zf-Di19 PF05605.7 EKE38103.1 - 0.16 12.0 3.1 2.3 8.4 0.1 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Borrelia_P83 PF05262.6 EKE38103.1 - 0.19 9.9 4.9 0.22 9.7 3.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1682 PF07946.9 EKE38103.1 - 1.2 7.9 10.9 1.5 7.5 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PhnA_Zn_Ribbon PF08274.7 EKE38103.1 - 3 7.7 9.3 18 5.1 0.1 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon YqfQ PF14181.1 EKE38103.1 - 7.9 6.4 9.7 12 5.9 6.7 1.3 1 0 0 1 1 1 0 YqfQ-like protein Ribosomal_L18e PF00828.14 EKE38104.1 - 4.8e-35 120.7 0.2 5.4e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ham1p_like PF01725.11 EKE38105.1 - 1.2e-45 155.1 0.0 1.4e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family BRK PF07533.11 EKE38105.1 - 0.012 15.0 0.3 0.022 14.2 0.2 1.4 1 0 0 1 1 1 0 BRK domain RhoGEF PF00621.15 EKE38107.1 - 2.3e-38 131.8 6.4 2.3e-38 131.8 4.5 1.9 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EKE38107.1 - 6.3e-17 61.2 10.3 1.7e-16 59.8 7.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE38107.1 - 1.4e-08 34.8 0.2 3.8e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 EKE38107.1 - 0.0056 16.5 8.0 0.0056 16.5 5.6 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Erf4 PF10256.4 EKE38107.1 - 0.11 12.4 1.3 0.32 10.8 0.1 2.4 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family HypA PF01155.14 EKE38107.1 - 0.62 9.7 7.3 0.91 9.2 3.7 2.2 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EKE38107.1 - 0.81 9.4 14.7 0.87 9.3 9.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Sulfotransfer_1 PF00685.22 EKE38108.1 - 8.6e-08 31.7 1.3 4.7e-07 29.3 0.9 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EKE38108.1 - 5.1e-05 24.2 0.0 0.0003 21.7 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase family Pkinase_Tyr PF07714.12 EKE38109.1 - 5.9e-14 51.7 0.1 1e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38109.1 - 1.1e-08 34.5 0.8 2.1e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain EGF_2 PF07974.8 EKE38109.1 - 0.01 15.9 12.4 0.01 15.9 8.6 4.9 5 0 0 5 5 5 0 EGF-like domain TFCD_C PF12612.3 EKE38109.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal CBM_25 PF03423.8 EKE38109.1 - 0.049 13.7 0.5 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Syndecan PF01034.15 EKE38109.1 - 0.33 10.6 2.7 4.4 7.0 0.5 2.4 2 0 0 2 2 2 0 Syndecan domain Potass_KdpF PF09604.5 EKE38109.1 - 3.3 7.6 7.3 0.38 10.6 1.8 1.8 2 0 0 2 2 2 0 F subunit of K+-transporting ATPase (Potass_KdpF) VSP PF03302.8 EKE38110.1 - 5.6 5.4 82.1 7.5 5.0 15.6 3.2 1 1 2 3 3 3 0 Giardia variant-specific surface protein DENN PF02141.16 EKE38112.1 - 1.1e-07 31.8 1.0 2.1e-07 30.8 0.4 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain PAP2_C PF14360.1 EKE38113.1 - 1.7e-11 44.1 11.0 1.7e-11 44.1 7.7 3.0 3 1 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EKE38113.1 - 1.1e-05 25.1 6.6 1.1e-05 25.1 4.6 2.8 2 1 1 3 3 3 1 PAP2 superfamily SH PF01445.12 EKE38113.1 - 1 9.0 11.8 0.56 9.8 2.5 3.3 3 0 0 3 3 3 0 Viral small hydrophobic protein Cation_efflux PF01545.16 EKE38115.1 - 1.5e-27 96.3 7.6 1.9e-27 96.0 5.3 1.0 1 0 0 1 1 1 1 Cation efflux family HAP PF03866.8 EKE38115.1 - 0.0039 17.0 1.1 0.0083 15.9 0.7 1.5 1 0 0 1 1 1 1 Hydrophobic abundant protein (HAP) DUF3483 PF11982.3 EKE38115.1 - 0.037 13.3 0.1 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) Paramyx_P_V_C PF03210.8 EKE38115.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF4658 PF15555.1 EKE38115.1 - 0.98 9.2 2.9 25 4.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) PIP5K PF01504.13 EKE38116.1 - 0.016 14.3 0.2 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.20 EKE38118.1 - 6.5e-79 264.7 2.9 5.8e-56 189.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38118.1 - 3.2e-53 180.4 0.9 1.4e-29 102.9 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EKE38118.1 - 1.5e-08 33.9 0.0 0.0045 15.9 0.0 3.2 3 0 0 3 3 3 2 Kinase-like RRM_1 PF00076.17 EKE38119.1 - 3.7e-26 90.5 5.1 6.4e-20 70.5 0.1 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE38119.1 - 9.5e-24 83.1 1.6 8.5e-18 64.1 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE38119.1 - 3.2e-13 49.2 2.9 7.4e-08 32.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-T PF15511.1 EKE38119.1 - 6.2 5.9 27.7 11 5.1 19.2 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ras PF00071.17 EKE38120.1 - 6.3e-53 178.4 0.6 7.5e-53 178.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38120.1 - 4.8e-16 59.3 0.0 8.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38120.1 - 5e-11 42.1 0.1 6.1e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE38120.1 - 4e-07 29.6 0.1 7.5e-07 28.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain HVSL PF09749.4 EKE38120.1 - 0.09 11.7 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein Rap_GAP PF02145.10 EKE38121.1 - 5.3e-51 172.6 1.0 1.1e-50 171.6 0.1 1.9 1 1 1 2 2 2 1 Rap/ran-GAP DUF4576 PF15144.1 EKE38121.1 - 0.0064 16.0 1.1 0.2 11.3 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4576) RhoGEF PF00621.15 EKE38122.1 - 5.1e-31 107.9 6.4 5.1e-31 107.9 4.5 4.2 4 1 1 5 5 5 1 RhoGEF domain ArfGap PF01412.13 EKE38122.1 - 1.8e-09 37.3 3.5 1.8e-09 37.3 2.4 4.7 3 3 1 4 4 4 1 Putative GTPase activating protein for Arf HSP70 PF00012.15 EKE38123.1 - 1.4e-23 82.6 0.0 1.6e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein DNase-RNase PF02577.9 EKE38124.1 - 0.12 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Bifunctional nuclease DENN PF02141.16 EKE38125.1 - 2.9e-10 40.1 0.3 3.2e-10 40.0 0.2 1.0 1 0 0 1 1 1 1 DENN (AEX-3) domain Ras PF00071.17 EKE38126.1 - 8.7e-48 161.7 3.4 1.2e-47 161.2 2.3 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE38126.1 - 4.2e-17 61.9 0.5 5.2e-17 61.6 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE38126.1 - 7.3e-17 61.9 0.3 1.2e-16 61.2 0.2 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE38126.1 - 0.0011 18.4 1.9 0.01 15.2 1.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE38126.1 - 0.0061 15.8 1.6 0.0094 15.1 0.1 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF1068 PF06364.7 EKE38126.1 - 0.014 14.9 0.3 0.019 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) AAA_22 PF13401.1 EKE38126.1 - 0.11 12.6 0.0 0.83 9.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain Vac14_Fab1_bd PF12755.2 EKE38127.1 - 0.12 12.8 4.0 9.7 6.6 0.0 3.6 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Arm PF00514.18 EKE38127.1 - 0.27 11.1 2.7 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Synaptobrevin PF00957.16 EKE38128.1 - 3.1e-08 33.1 1.7 5e-08 32.4 1.2 1.3 1 0 0 1 1 1 1 Synaptobrevin XRN_N PF03159.13 EKE38129.1 - 5.5e-97 323.8 0.0 1.1e-96 322.8 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF3298 PF11738.3 EKE38129.1 - 0.24 11.9 2.0 1.6 9.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) DUF3106 PF11304.3 EKE38129.1 - 2 8.8 8.4 0.089 13.2 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) AAA_18 PF13238.1 EKE38130.1 - 1.1e-07 32.1 0.0 2e-06 28.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKE38130.1 - 8.2e-05 22.7 0.0 0.00015 21.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE38130.1 - 0.0005 20.8 0.1 0.00086 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKE38130.1 - 0.0039 17.3 1.0 0.0094 16.1 0.1 2.1 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 EKE38130.1 - 0.004 16.1 0.1 0.01 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 EKE38130.1 - 0.0053 15.4 0.1 0.0089 14.6 0.0 1.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 EKE38130.1 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EKE38130.1 - 0.0076 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.12 EKE38130.1 - 0.0085 15.4 0.2 3.6 6.9 0.1 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA PF00004.24 EKE38130.1 - 0.014 15.5 0.0 0.045 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EKE38130.1 - 0.016 15.0 1.5 0.075 12.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EKE38130.1 - 0.025 14.0 1.1 0.048 13.0 0.8 1.7 1 1 0 1 1 1 0 AAA-like domain Guanylate_kin PF00625.16 EKE38130.1 - 0.029 13.7 0.7 1.1 8.7 0.0 2.9 2 1 1 3 3 3 0 Guanylate kinase DUF258 PF03193.11 EKE38130.1 - 0.035 13.3 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EKE38130.1 - 0.037 13.6 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EKE38130.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 EKE38130.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EKE38130.1 - 0.084 12.3 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EKE38130.1 - 0.13 12.8 0.4 0.32 11.5 0.3 1.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EKE38130.1 - 0.13 11.8 1.2 0.39 10.2 0.8 1.8 1 1 1 2 2 2 0 P-loop containing region of AAA domain DUF1777 PF08648.7 EKE38132.1 - 3e-07 30.3 17.1 7.7e-07 29.0 11.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) Pkinase PF00069.20 EKE38133.1 - 2.2e-58 197.4 0.0 2.5e-45 154.6 0.0 3.3 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38133.1 - 2.7e-35 121.6 0.0 4.6e-26 91.4 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKE38133.1 - 7.4e-05 21.8 0.0 0.0082 15.1 0.0 3.3 3 1 0 3 3 3 1 Kinase-like AAA_23 PF13476.1 EKE38134.1 - 2.2e-17 64.0 5.7 2.2e-17 64.0 4.0 5.7 1 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EKE38134.1 - 9.2e-07 28.3 57.7 1.2e-05 24.6 40.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EKE38134.1 - 1.6e-06 26.9 95.6 5.2e-05 21.9 16.5 5.7 3 2 1 5 5 5 3 AAA domain AAA_21 PF13304.1 EKE38134.1 - 1.1e-05 25.5 0.2 1.1e-05 25.5 0.1 4.3 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EKE38134.1 - 0.00093 18.6 0.0 0.063 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain CENP-Q PF13094.1 EKE38134.1 - 0.0018 18.3 4.5 0.0018 18.3 3.1 4.9 3 1 1 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit AAA_29 PF13555.1 EKE38134.1 - 0.0028 17.1 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Retrotrans_gag PF03732.12 EKE38134.1 - 1.9 8.5 10.3 2.4 8.3 0.6 4.2 4 0 0 4 4 4 0 Retrotransposon gag protein MscS_porin PF12795.2 EKE38134.1 - 5 6.3 69.2 0.045 13.0 15.9 5.3 2 2 3 5 5 5 0 Mechanosensitive ion channel porin domain DUF273 PF03314.9 EKE38135.1 - 0.0068 15.7 0.5 0.0096 15.2 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF273 DOCK-C2 PF14429.1 EKE38136.1 - 1.3e-07 31.4 0.2 4.9e-07 29.5 0.1 2.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Lung_7-TM_R PF06814.8 EKE38137.1 - 2.2e-12 46.5 23.6 4.2e-12 45.6 16.3 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EKE38137.1 - 1.1e-08 34.5 15.1 1.1e-08 34.5 10.4 2.6 2 1 1 3 3 3 1 Rhodopsin-like GPCR transmembrane domain Cation_ATPase_N PF00690.21 EKE38137.1 - 0.15 11.5 0.4 0.52 9.8 0.3 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SNARE PF05739.14 EKE38138.1 - 8.4e-10 38.1 7.5 1.3e-09 37.5 5.2 1.3 1 0 0 1 1 1 1 SNARE domain DUF812 PF05667.6 EKE38138.1 - 0.027 13.0 7.9 0.029 12.8 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Herpes_UL92 PF03048.9 EKE38138.1 - 0.11 12.0 4.2 0.14 11.7 2.9 1.1 1 0 0 1 1 1 0 UL92 family DUF3186 PF11382.3 EKE38138.1 - 0.17 11.0 2.4 0.2 10.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) IATP PF04568.7 EKE38138.1 - 0.21 11.6 5.8 0.37 10.8 3.5 1.8 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ADIP PF11559.3 EKE38138.1 - 0.3 10.9 8.1 0.37 10.6 5.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_GPO PF05929.6 EKE38138.1 - 0.36 10.0 3.0 0.4 9.9 2.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2968 PF11180.3 EKE38138.1 - 0.43 9.9 4.9 0.49 9.7 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SlyX PF04102.7 EKE38138.1 - 0.51 10.7 4.9 6.2 7.2 0.2 2.4 1 1 1 2 2 2 0 SlyX IncA PF04156.9 EKE38138.1 - 0.53 9.8 9.0 0.65 9.5 6.3 1.1 1 0 0 1 1 1 0 IncA protein YkuI_C PF10388.4 EKE38138.1 - 0.53 9.9 5.9 0.81 9.3 4.1 1.3 1 1 0 1 1 1 0 EAL-domain associated signalling protein domain PAP_central PF04928.12 EKE38138.1 - 0.54 9.0 5.2 0.63 8.8 3.6 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain Nup54 PF13874.1 EKE38138.1 - 0.81 9.3 7.6 0.66 9.6 0.3 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GLE1 PF07817.8 EKE38138.1 - 0.81 8.5 5.3 0.93 8.3 3.7 1.1 1 0 0 1 1 1 0 GLE1-like protein Wx5_PLAF3D7 PF09688.5 EKE38138.1 - 1 9.2 8.3 1.2 9.0 4.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) RE_Alw26IDE PF09665.5 EKE38138.1 - 1.9 7.1 7.8 2.3 6.8 5.4 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF4446 PF14584.1 EKE38138.1 - 4.4 7.1 6.9 3.5 7.4 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF1664 PF07889.7 EKE38138.1 - 5.2 6.8 7.8 27 4.5 5.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.11 EKE38138.1 - 7.4 6.8 11.4 11 6.2 7.9 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Laminin_G_3 PF13385.1 EKE38139.1 - 8.1e-07 29.4 0.1 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Coatamer_beta_C PF07718.7 EKE38140.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Coatomer beta C-terminal region NAP PF00956.13 EKE38141.1 - 9.5e-39 132.9 0.6 9.5e-39 132.9 0.4 1.9 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) ABC_tran_2 PF12848.2 EKE38141.1 - 0.015 15.1 1.3 0.031 14.1 0.9 1.5 1 0 0 1 1 1 0 ABC transporter Nop14 PF04147.7 EKE38141.1 - 0.42 8.4 9.0 0.6 7.9 6.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EKE38141.1 - 0.58 8.1 5.7 1 7.3 4.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RasGEF PF00617.14 EKE38142.1 - 3.5e-47 160.5 0.2 3.5e-47 160.5 0.2 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE38142.1 - 4.7e-11 42.7 0.2 1.4e-10 41.1 0.0 1.9 1 1 1 2 2 2 1 RasGEF N-terminal motif DUF4404 PF14357.1 EKE38142.1 - 0.038 14.4 0.2 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Dynamin_N PF00350.18 EKE38143.1 - 3.5e-10 39.9 0.4 3.5e-10 39.9 0.2 4.5 5 0 0 5 5 5 1 Dynamin family MMR_HSR1 PF01926.18 EKE38143.1 - 0.00025 20.9 0.5 0.00025 20.9 0.3 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase YjeF_N PF03853.10 EKE38143.1 - 0.032 13.8 0.1 0.079 12.5 0.1 1.7 1 0 0 1 1 1 0 YjeF-related protein N-terminus Abi_C PF14355.1 EKE38143.1 - 0.045 13.7 0.5 13 5.7 0.1 3.0 2 0 0 2 2 2 0 Abortive infection C-terminus DUF651 PF04895.7 EKE38143.1 - 0.096 12.3 0.0 0.096 12.3 0.0 3.5 4 0 0 4 4 4 0 Archaeal protein of unknown function (DUF651) NPV_P10 PF05531.7 EKE38143.1 - 1 9.6 8.1 14 5.9 0.4 3.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_17 PF13207.1 EKE38143.1 - 3.6 8.4 6.1 8.1 7.2 2.1 3.3 2 1 0 2 2 2 0 AAA domain DUF3530 PF12048.3 EKE38143.1 - 6.3 5.6 9.2 2.8 6.8 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) LRR_5 PF13306.1 EKE38144.1 - 1.4e-58 196.1 31.3 2.3e-26 92.0 2.2 5.8 3 1 3 6 6 6 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38144.1 - 1.7e-17 62.9 9.9 0.0018 17.9 0.0 7.1 3 2 5 8 8 8 7 Leucine rich repeat Crystall PF00030.14 EKE38144.1 - 0.24 11.3 2.0 13 5.8 0.1 3.4 3 0 0 3 3 3 0 Beta/Gamma crystallin RdRP PF05183.7 EKE38145.1 - 1.3e-100 337.8 0.1 2e-100 337.2 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase MatE PF01554.13 EKE38145.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 MatE LRR_5 PF13306.1 EKE38148.1 - 7.2e-86 284.4 45.3 4.5e-33 113.7 5.9 3.9 1 1 3 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38148.1 - 1.2e-31 108.2 19.5 3e-06 26.8 1.4 7.5 1 1 5 7 7 7 7 Leucine rich repeat Tetraspannin PF00335.15 EKE38149.1 - 8.9e-05 21.8 15.8 0.00019 20.7 10.9 1.5 1 1 0 1 1 1 1 Tetraspanin family O-antigen_lig PF13425.1 EKE38149.1 - 0.00063 19.7 4.3 0.0091 15.9 1.6 2.1 2 0 0 2 2 2 1 O-antigen ligase like membrane protein ABC2_membrane_2 PF12679.2 EKE38149.1 - 0.016 14.1 0.5 0.057 12.2 0.4 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein GP41 PF00517.12 EKE38149.1 - 0.016 14.7 1.6 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Retroviral envelope protein InaF-motif PF15018.1 EKE38149.1 - 0.063 12.7 0.1 0.063 12.7 0.1 2.0 2 0 0 2 2 2 0 TRP-interacting helix DUF2207 PF09972.4 EKE38149.1 - 0.13 10.7 5.9 0.41 9.1 2.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EamA PF00892.15 EKE38149.1 - 0.33 11.0 10.8 0.075 13.0 3.7 2.0 2 0 0 2 2 2 0 EamA-like transporter family Pox_A14 PF05767.7 EKE38149.1 - 0.55 10.2 6.0 11 6.1 1.2 2.7 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 HMG_box PF00505.14 EKE38150.1 - 8.8e-13 48.3 11.4 1.3e-10 41.4 1.1 2.6 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE38150.1 - 3.6e-11 43.2 2.8 3.6e-11 43.2 1.9 2.0 2 0 0 2 2 2 1 HMG-box domain Vac_ImportDeg PF09783.4 EKE38150.1 - 0.0039 16.7 6.0 0.76 9.2 1.7 2.6 1 1 1 2 2 2 2 Vacuolar import and degradation protein RNA_pol_3_Rpc31 PF11705.3 EKE38150.1 - 5.9 6.7 9.7 9.8 6.0 6.7 1.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Acetyltransf_1 PF00583.19 EKE38151.1 - 3.7e-17 62.1 0.1 5.1e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE38151.1 - 4.9e-13 49.0 0.5 6.9e-13 48.5 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKE38151.1 - 2.9e-10 39.7 0.0 5.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EKE38151.1 - 4.8e-09 36.2 0.0 6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKE38151.1 - 8.2e-08 32.5 0.1 9.8e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKE38151.1 - 1e-07 32.0 1.1 1.5e-07 31.4 0.8 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE38151.1 - 5.5e-07 29.7 0.0 7.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKE38151.1 - 0.00059 19.6 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase UCH PF00443.24 EKE38153.1 - 6.8e-58 195.9 0.0 1.5e-57 194.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE38153.1 - 1.1e-15 57.8 11.9 1.2e-10 41.3 0.1 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EKE38153.1 - 0.0014 18.9 0.1 0.014 15.7 0.0 2.7 2 0 0 2 2 2 1 DUSP domain Ribosomal_L40e PF01020.12 EKE38154.1 - 1.5e-29 101.3 6.6 1.7e-29 101.1 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L40e family zf-CHY PF05495.7 EKE38154.1 - 0.039 14.1 1.4 0.048 13.8 1.0 1.1 1 0 0 1 1 1 0 CHY zinc finger Peptidase_S74 PF13884.1 EKE38155.1 - 4.1e-15 55.6 0.1 8.3e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase PSI PF01437.20 EKE38155.1 - 0.24 11.6 12.4 0.52 10.5 8.6 1.5 1 0 0 1 1 1 0 Plexin repeat PRP38 PF03371.10 EKE38156.1 - 5.1e-26 91.3 0.1 6.9e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 PRP38 family DUF1509 PF07420.6 EKE38156.1 - 8 5.6 11.9 10 5.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Mob1_phocein PF03637.12 EKE38158.1 - 3e-52 176.7 0.8 3.6e-52 176.5 0.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family Herpes_U44 PF04533.8 EKE38158.1 - 0.081 12.1 0.0 0.18 11.0 0.0 1.6 1 1 0 1 1 1 0 Herpes virus U44 protein TRAP_beta PF05753.9 EKE38161.1 - 4.9e-12 45.3 0.9 9.3e-12 44.4 0.6 1.4 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.13 EKE38161.1 - 2.5e-07 30.6 0.4 2.5e-07 30.6 0.3 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF11 CARDB PF07705.6 EKE38161.1 - 0.033 14.2 0.3 0.078 13.0 0.2 1.7 1 1 0 1 1 1 0 CARDB DUF1899 PF08953.6 EKE38162.1 - 3.6e-25 87.3 0.2 6.6e-25 86.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EKE38162.1 - 5.1e-24 83.2 9.0 8.3e-09 35.0 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Rrn6 PF10214.4 EKE38162.1 - 0.081 11.0 0.1 0.093 10.8 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1900 PF08954.6 EKE38163.1 - 2.1e-48 163.2 0.0 3.2e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) Prefoldin_2 PF01920.15 EKE38163.1 - 0.0071 16.0 0.2 0.0096 15.6 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF641 PF04859.7 EKE38163.1 - 0.072 12.8 0.3 0.097 12.4 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.17 EKE38163.1 - 0.1 12.6 1.3 0.16 12.0 0.9 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.4 EKE38163.1 - 0.11 12.2 0.7 0.15 11.9 0.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Syntaphilin PF15290.1 EKE38163.1 - 0.14 11.5 1.3 0.21 11.0 0.9 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp TMF_DNA_bd PF12329.3 EKE38163.1 - 0.27 11.0 3.6 0.13 12.1 0.8 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IFP_35_N PF07334.8 EKE38163.1 - 0.28 11.2 2.1 0.52 10.3 1.4 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pro_isomerase PF00160.16 EKE38164.1 - 4.5e-43 147.1 0.2 5.1e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Chlorosome_CsmC PF11098.3 EKE38165.1 - 0.00074 19.2 20.7 0.0033 17.1 2.5 2.2 2 0 0 2 2 2 2 Chlorosome envelope protein C RmuC PF02646.11 EKE38165.1 - 0.0059 15.4 1.7 0.0059 15.4 1.2 2.5 1 1 1 2 2 2 1 RmuC family MCPsignal PF00015.16 EKE38165.1 - 0.0064 16.0 16.8 0.0088 15.6 1.1 3.0 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE_C PF12352.3 EKE38165.1 - 0.024 14.6 0.3 38 4.4 0.1 3.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus TMP_2 PF06791.8 EKE38165.1 - 0.028 14.0 15.5 0.096 12.2 2.2 2.5 2 1 0 2 2 2 0 Prophage tail length tape measure protein Laminin_I PF06008.9 EKE38165.1 - 0.033 13.4 2.1 0.064 12.5 1.1 1.7 1 1 1 2 2 2 0 Laminin Domain I Syntaxin PF00804.20 EKE38165.1 - 0.19 11.9 5.2 6.1 7.0 0.1 3.4 2 2 0 3 3 3 0 Syntaxin DUF948 PF06103.6 EKE38165.1 - 0.5 10.2 3.5 3.5 7.5 0.3 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.6 EKE38165.1 - 2.3 7.9 4.4 1.4 8.6 1.9 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) QLQ PF08880.6 EKE38166.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 QLQ Rhodanese PF00581.15 EKE38167.1 - 8.6e-13 48.6 0.0 2e-12 47.4 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain MvaI_BcnI PF15515.1 EKE38167.1 - 0.0084 16.1 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 MvaI/BcnI restriction endonuclease family Ribonuclease_T2 PF00445.13 EKE38168.1 - 4.7e-28 98.0 8.1 6.2e-28 97.7 5.6 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF2492 PF10678.4 EKE38168.1 - 0.016 15.2 0.0 0.06 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) DUF4223 PF13978.1 EKE38168.1 - 0.11 12.2 0.3 0.38 10.5 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) RNB PF00773.14 EKE38169.1 - 9.7e-95 317.5 1.1 7.3e-94 314.6 0.0 2.5 2 1 1 3 3 3 1 RNB domain 7TM_GPCR_Sra PF02117.11 EKE38171.1 - 0.056 12.0 0.8 0.2 10.2 0.2 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra DUF3708 PF12501.3 EKE38171.1 - 0.2 11.4 0.1 0.2 11.4 0.1 2.0 2 1 1 3 3 3 0 Phosphate ATP-binding cassette transporter CSF-1 PF05337.6 EKE38171.1 - 6.4 6.0 7.3 5.3 6.3 4.0 1.7 1 1 1 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) Ribosomal_L22 PF00237.14 EKE38172.1 - 5.5e-32 109.8 0.2 8.2e-32 109.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SPRY PF00622.23 EKE38173.1 - 3.7e-14 52.8 1.3 6.8e-14 52.0 0.9 1.5 1 0 0 1 1 1 1 SPRY domain Laminin_II PF06009.7 EKE38173.1 - 0.069 12.9 0.9 0.25 11.0 0.2 2.0 2 0 0 2 2 2 0 Laminin Domain II Paramyx_P_V_C PF03210.8 EKE38173.1 - 0.23 11.3 2.5 0.65 9.8 1.8 1.7 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal ORF6C PF10552.4 EKE38173.1 - 1.5 8.5 6.4 0.32 10.7 1.6 1.9 2 0 0 2 2 2 0 ORF6C domain DENN PF02141.16 EKE38174.1 - 2.1e-27 96.0 0.6 2.1e-27 96.0 0.4 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 EKE38174.1 - 1.8e-09 37.3 0.1 4.7e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EKE38174.1 - 5.1e-07 29.6 1.9 7.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 dDENN domain PH PF00169.24 EKE38174.1 - 0.0042 17.2 0.1 0.0042 17.2 0.1 4.5 3 2 0 3 3 3 1 PH domain MFS_1 PF07690.11 EKE38175.1 - 9.4e-35 119.9 25.9 8.9e-27 93.7 0.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM176 PF14851.1 EKE38175.1 - 0.0034 17.0 0.2 0.74 9.4 0.1 2.6 2 0 0 2 2 2 2 FAM176 family RhoGAP PF00620.22 EKE38176.1 - 5.6e-26 90.9 0.0 2.5e-25 88.8 0.0 2.2 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EKE38176.1 - 9.4e-17 60.8 23.2 1.8e-11 43.9 2.9 3.0 3 0 0 3 3 3 2 LIM domain Peptidase_S46 PF10459.4 EKE38176.1 - 7.9 4.7 24.4 15 3.8 16.9 1.4 1 0 0 1 1 1 0 Peptidase S46 Anth_Ig PF05587.8 EKE38177.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Anthrax receptor extracellular domain Ras PF00071.17 EKE38178.1 - 3.3e-54 182.6 0.2 3.9e-54 182.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38178.1 - 2.7e-24 85.9 0.1 5.6e-24 84.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EKE38178.1 - 3.1e-13 49.5 0.0 3.3e-12 46.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EKE38178.1 - 3.2e-13 49.3 0.0 4.5e-13 48.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE38178.1 - 1.6e-06 28.0 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE38178.1 - 3.6e-06 26.2 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE38178.1 - 2.4e-05 24.4 0.0 0.00011 22.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EKE38178.1 - 3.5e-05 23.0 0.0 5.8e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKE38178.1 - 0.00029 20.3 0.1 0.0011 18.4 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE38178.1 - 0.0014 17.8 0.1 0.0048 16.0 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EKE38178.1 - 0.0056 16.2 0.1 0.21 11.1 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EKE38178.1 - 0.008 16.1 0.0 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EKE38178.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EKE38178.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_15 PF13175.1 EKE38178.1 - 0.032 13.3 0.2 0.032 13.3 0.1 1.2 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 EKE38178.1 - 0.047 12.7 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.24 EKE38178.1 - 0.054 13.6 0.0 0.086 13.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EKE38178.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.7 EKE38178.1 - 0.07 12.4 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.1 EKE38178.1 - 0.079 12.5 0.4 0.3 10.6 0.0 2.1 2 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EKE38178.1 - 0.086 12.7 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKE38178.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain HHH_5 PF14520.1 EKE38179.1 - 0.0013 18.8 3.0 0.028 14.6 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HMGL-like PF00682.14 EKE38179.1 - 0.014 15.0 1.6 0.014 15.0 1.1 2.0 2 0 0 2 2 2 0 HMGL-like Phage_GPO PF05929.6 EKE38179.1 - 0.84 8.8 15.0 0.054 12.7 6.0 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF911 PF06023.7 EKE38179.1 - 2.3 7.3 9.9 1 8.4 4.1 2.1 1 1 2 3 3 3 0 Archaeal protein of unknown function (DUF911) Muted PF14942.1 EKE38179.1 - 5.2 6.9 14.6 0.1 12.4 3.8 2.5 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Rap_GAP PF02145.10 EKE38180.1 - 1.3e-54 184.4 1.4 1.4e-54 184.3 0.2 1.6 2 0 0 2 2 2 1 Rap/ran-GAP RabGAP-TBC PF00566.13 EKE38181.1 - 1.5e-29 103.0 8.4 1.9e-27 96.1 3.5 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Interfer-bind PF09294.5 EKE38181.1 - 0.082 12.9 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Peptidase_S74 PF13884.1 EKE38182.1 - 2.2e-12 46.9 0.2 6.8e-12 45.3 0.1 1.9 1 0 0 1 1 1 1 Chaperone of endosialidase DUF1212 PF06738.7 EKE38182.1 - 1.9 7.9 14.3 0.66 9.4 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) Thioredoxin PF00085.15 EKE38183.1 - 2.8e-10 39.7 0.3 3.3e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 EKE38183.1 - 0.09 12.7 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin WT1 PF02165.10 EKE38183.1 - 0.12 11.4 0.9 0.14 11.2 0.7 1.1 1 0 0 1 1 1 0 Wilm's tumour protein Cullin_binding PF03556.10 EKE38184.1 - 6.7e-05 23.0 0.2 0.00015 21.8 0.1 1.6 1 0 0 1 1 1 1 Cullin binding DUF1827 PF08860.5 EKE38184.1 - 0.098 12.7 0.2 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) RasGEF PF00617.14 EKE38185.1 - 8.6e-59 198.4 0.0 2.7e-58 196.8 0.0 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE38185.1 - 1.5e-15 57.2 0.3 1.5e-15 57.2 0.2 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif Pkinase PF00069.20 EKE38189.1 - 2.1e-56 190.9 0.0 3.2e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38189.1 - 4.4e-42 143.9 0.0 6.8e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE38189.1 - 4.5e-07 29.1 0.0 7.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 EKE38189.1 - 6.9e-05 23.1 0.0 0.0002 21.6 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain zf-MIZ PF02891.15 EKE38190.1 - 3.9e-13 48.6 3.4 3.9e-13 48.6 2.4 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EKE38190.1 - 1.7e-06 27.4 1.0 6.8e-06 25.5 0.7 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mit_ribos_Mrp51 PF11709.3 EKE38192.1 - 1.3 8.2 13.2 72 2.4 9.2 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit UPF0102 PF02021.12 EKE38192.1 - 2.2 8.2 5.7 0.8 9.6 0.8 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0102 HTH_Tnp_IS630 PF01710.11 EKE38192.1 - 6.4 6.4 10.8 0.11 12.1 0.9 2.4 2 1 0 2 2 2 0 Transposase TRAP_alpha PF03896.11 EKE38193.1 - 0.14 11.0 4.2 0.15 10.9 2.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4637 PF15470.1 EKE38193.1 - 2.3 7.8 5.4 3 7.4 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.9 EKE38193.1 - 3.6 7.0 8.0 5.3 6.5 5.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2890 PF11081.3 EKE38193.1 - 3.7 7.5 9.4 5.1 7.1 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HABP4_PAI-RBP1 PF04774.10 EKE38193.1 - 9.9 6.7 10.3 14 6.2 7.1 1.1 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DENN PF02141.16 EKE38194.1 - 1.6e-14 54.0 0.7 1.6e-14 54.0 0.5 2.3 3 0 0 3 3 3 1 DENN (AEX-3) domain dDENN PF03455.14 EKE38194.1 - 1.3e-08 34.7 2.0 1.3e-08 34.7 1.4 2.2 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 EKE38194.1 - 0.00032 20.6 0.6 0.0012 18.7 0.4 2.1 1 1 0 1 1 1 1 uDENN domain CNH PF00780.17 EKE38195.1 - 0.043 13.2 2.3 0.041 13.3 0.4 2.0 1 1 0 1 1 1 0 CNH domain EamA PF00892.15 EKE38196.1 - 2.2e-06 27.7 1.4 2.2e-06 27.7 1.0 5.0 4 1 0 4 4 4 1 EamA-like transporter family DUF1418 PF07214.7 EKE38196.1 - 0.38 10.3 5.1 4.7 6.9 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1418) PRMT5 PF05185.11 EKE38197.1 - 4.3e-16 58.8 0.0 5.4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 EKE38197.1 - 5.5e-12 45.5 0.1 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKE38197.1 - 3.6e-11 42.7 0.0 4.9e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EKE38197.1 - 5.5e-10 39.8 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE38197.1 - 1.6e-08 34.5 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE38197.1 - 5.4e-07 29.1 0.0 8.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EKE38197.1 - 8.7e-07 28.7 0.0 1.3e-05 24.9 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE38197.1 - 1.2e-06 28.8 0.0 2.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EKE38197.1 - 3.8e-06 26.6 0.1 6e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 EKE38197.1 - 8.5e-06 25.0 0.1 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EKE38197.1 - 0.0001 22.6 0.0 0.00093 19.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EKE38197.1 - 0.00027 19.7 0.0 0.00039 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EKE38197.1 - 0.00077 19.8 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EKE38197.1 - 0.0041 16.3 0.1 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 Tellurite resistance protein TehB FtsJ PF01728.14 EKE38197.1 - 0.0042 17.1 0.0 0.0077 16.2 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.12 EKE38197.1 - 0.0062 15.5 0.0 0.022 13.7 0.0 1.8 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.1 EKE38197.1 - 0.0095 16.7 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EKE38197.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EKE38197.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.14 EKE38197.1 - 0.025 14.1 0.2 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EKE38197.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase 2TM PF13239.1 EKE38198.1 - 0.013 15.5 1.2 0.013 15.5 0.8 2.7 2 1 0 2 2 2 0 2TM domain DUF4149 PF13664.1 EKE38198.1 - 0.9 9.6 7.6 0.46 10.5 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) GCC2_GCC3 PF07699.8 EKE38199.1 - 1.1e-14 53.7 80.9 2.1e-05 24.0 6.6 9.1 1 1 5 8 8 8 7 GCC2 and GCC3 NCD3G PF07562.9 EKE38199.1 - 2.2e-09 36.8 56.0 0.0015 18.1 4.8 6.8 4 2 1 6 6 6 5 Nine Cysteines Domain of family 3 GPCR Pkinase PF00069.20 EKE38200.1 - 5.7e-69 232.1 0.0 6.5e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38200.1 - 6.7e-34 117.1 0.0 8.4e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE38200.1 - 0.00052 19.0 0.0 0.00061 18.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EKE38201.1 - 3.8e-48 163.8 0.7 7.8e-48 162.8 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38201.1 - 1.6e-45 155.2 0.0 2.7e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.8 EKE38201.1 - 3.3e-05 22.7 32.2 3.3e-05 22.7 22.3 4.7 1 1 3 4 4 4 2 Giardia variant-specific surface protein Kinase-like PF14531.1 EKE38201.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Methyltransf_16 PF10294.4 EKE38203.1 - 9.6e-15 54.4 0.0 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EKE38203.1 - 4.7e-09 36.8 0.0 7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE38203.1 - 1.8e-08 34.1 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE38203.1 - 6.7e-08 32.4 0.0 2e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE38203.1 - 2.2e-07 30.4 0.0 2.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EKE38203.1 - 4.4e-06 27.0 0.0 6.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EKE38203.1 - 1.2e-05 24.5 0.1 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 EKE38203.1 - 0.00012 22.4 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE38203.1 - 0.00015 22.1 0.0 0.00024 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE38203.1 - 0.0004 20.3 0.0 0.00054 19.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKE38203.1 - 0.0026 17.3 0.1 0.007 15.9 0.0 1.7 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0146 PF03686.8 EKE38203.1 - 0.0062 16.3 0.2 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0146) RrnaAD PF00398.15 EKE38203.1 - 0.035 13.1 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EKE38203.1 - 0.08 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.20 EKE38204.1 - 2.1e-49 168.0 0.4 2.1e-49 168.0 0.3 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38204.1 - 2e-31 109.0 0.8 6e-31 107.4 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE38204.1 - 0.014 14.4 0.1 0.071 12.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Med21 PF11221.3 EKE38205.1 - 1.1e-08 35.1 0.8 1.9e-08 34.4 0.6 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Katanin_con80 PF13925.1 EKE38206.1 - 0.0038 16.9 6.6 0.31 10.7 0.1 3.4 4 1 0 4 4 4 2 con80 domain of Katanin CK_II_beta PF01214.13 EKE38207.1 - 4.5e-65 218.6 0.0 5.2e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Choline_kinase PF01633.15 EKE38208.1 - 7e-44 149.9 0.4 1.5e-43 148.8 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKE38208.1 - 3.3e-06 27.0 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HVSL PF09749.4 EKE38208.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein EcKinase PF02958.15 EKE38208.1 - 0.031 13.4 0.9 0.066 12.3 0.6 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Arginase PF00491.16 EKE38209.1 - 1.2e-57 195.3 0.0 1.3e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_4 PF01063.14 EKE38211.1 - 2.1e-26 92.7 0.1 3.5e-26 92.1 0.1 1.3 1 1 0 1 1 1 1 Aminotransferase class IV Aminotran_1_2 PF00155.16 EKE38213.1 - 1.9e-22 79.7 0.0 2.3e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EKE38213.1 - 0.062 11.5 0.0 0.17 10.1 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF4145 PF13643.1 EKE38213.1 - 0.086 12.7 0.3 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Aminotran_1_2 PF00155.16 EKE38214.1 - 1.6e-16 60.2 0.0 1.9e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4181 PF13789.1 EKE38217.1 - 0.019 14.8 0.7 0.021 14.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) ComFB PF10719.4 EKE38218.1 - 0.073 12.8 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Late competence development protein ComFB zf-LITAF-like PF10601.4 EKE38220.1 - 1.8e-19 69.3 15.3 2.6e-19 68.8 10.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-FPG_IleRS PF06827.9 EKE38220.1 - 0.0069 16.0 5.4 0.12 12.0 0.4 2.5 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS 5TM-5TMR_LYT PF07694.7 EKE38220.1 - 0.2 10.9 1.4 0.27 10.5 0.9 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Abhydrolase_6 PF12697.2 EKE38222.1 - 2.4e-06 27.5 0.0 3.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE38222.1 - 0.00026 20.7 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EKE38222.1 - 0.00085 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EKE38222.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 EKE38222.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EKE38222.1 - 0.029 13.9 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EKE38222.1 - 0.041 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EKE38222.1 - 0.056 13.6 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PAP_central PF04928.12 EKE38225.1 - 1.5e-51 174.6 1.3 2e-51 174.2 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.18 EKE38225.1 - 8.9e-07 29.1 0.1 2.8e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 EKE38225.1 - 0.0002 20.9 0.0 0.0009 18.7 0.0 2.3 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain UPF0160 PF03690.8 EKE38226.1 - 5.5e-81 272.4 0.0 6.3e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rifin_STEVOR PF02009.11 EKE38227.1 - 2.3e-05 24.1 5.5 2.5e-05 24.0 3.8 1.1 1 0 0 1 1 1 1 Rifin/stevor family Dispanin PF04505.7 EKE38227.1 - 0.00069 19.1 3.7 0.0024 17.3 2.6 1.9 1 1 0 1 1 1 1 Interferon-induced transmembrane protein SNARE PF05739.14 EKE38227.1 - 0.0015 18.1 5.3 0.0025 17.4 3.7 1.3 1 1 0 1 1 1 1 SNARE domain DUF2407_C PF13373.1 EKE38227.1 - 0.0039 17.1 0.1 0.0051 16.7 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain Use1 PF09753.4 EKE38227.1 - 0.0042 16.5 1.2 0.0049 16.3 0.8 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF912 PF06024.7 EKE38227.1 - 0.022 14.8 3.2 0.034 14.1 2.2 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GP41 PF00517.12 EKE38227.1 - 0.026 14.0 0.6 0.032 13.7 0.4 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Prominin PF05478.6 EKE38227.1 - 0.03 11.8 0.2 0.033 11.7 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF3040 PF11239.3 EKE38227.1 - 0.036 14.0 0.2 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SP_C-Propep PF08999.5 EKE38227.1 - 0.04 13.3 1.4 0.056 12.9 0.9 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2562 PF10814.3 EKE38227.1 - 0.042 13.8 1.2 0.059 13.3 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) DUF4394 PF14339.1 EKE38227.1 - 0.056 12.7 0.1 0.058 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) DUF3708 PF12501.3 EKE38227.1 - 0.059 13.2 1.2 0.071 12.9 0.8 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF2207 PF09972.4 EKE38227.1 - 0.065 11.8 0.1 0.066 11.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MMPL PF03176.10 EKE38227.1 - 0.068 11.8 2.7 0.078 11.6 1.8 1.1 1 0 0 1 1 1 0 MMPL family Synaptobrevin PF00957.16 EKE38227.1 - 0.07 12.7 5.9 0.12 12.0 4.1 1.5 1 1 0 1 1 1 0 Synaptobrevin Rhabdo_glycop PF00974.13 EKE38227.1 - 0.12 10.5 0.1 0.13 10.4 0.1 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein MtrB PF05440.7 EKE38227.1 - 0.17 11.9 2.9 0.31 11.1 2.0 1.5 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B SseC PF04888.7 EKE38227.1 - 0.26 10.6 7.2 0.32 10.3 5.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Renin_r PF07850.9 EKE38227.1 - 0.26 11.6 3.0 0.38 11.1 2.0 1.3 1 1 0 1 1 1 0 Renin receptor-like protein PV-1 PF06637.6 EKE38227.1 - 0.33 9.4 3.2 0.39 9.2 2.2 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Protocadherin PF08374.6 EKE38227.1 - 0.45 10.1 6.1 0.38 10.3 3.6 1.4 1 1 0 1 1 1 0 Protocadherin Herpes_US9 PF06072.6 EKE38227.1 - 0.48 10.2 7.5 0.19 11.5 3.6 1.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Chordopox_A33R PF05966.7 EKE38227.1 - 1.3 7.7 4.0 1.7 7.4 1.9 1.7 1 1 1 2 2 2 0 Chordopoxvirus A33R protein DUF2951 PF11166.3 EKE38227.1 - 1.4 8.8 7.0 4.7 7.1 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) LRR19-TM PF15176.1 EKE38227.1 - 2.2 8.0 5.5 2.1 8.1 2.9 1.6 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3827 PF12877.2 EKE38227.1 - 7.8 4.4 18.8 4.3 5.3 10.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3827) NAD_binding_1 PF00175.16 EKE38228.1 - 1.2 9.7 3.9 2.4 8.7 0.7 2.4 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4201 PF13870.1 EKE38230.1 - 0.009 15.4 6.7 0.011 15.2 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF919 PF06034.6 EKE38230.1 - 0.012 15.1 7.7 0.02 14.4 5.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF3417 PF11897.3 EKE38230.1 - 0.016 15.1 0.4 0.024 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) ATG16 PF08614.6 EKE38230.1 - 0.019 14.7 7.2 0.027 14.3 5.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Peptidase_C1_2 PF03051.10 EKE38230.1 - 0.066 11.7 2.0 0.074 11.5 1.4 1.0 1 0 0 1 1 1 0 Peptidase C1-like family Med4 PF10018.4 EKE38230.1 - 0.081 12.3 5.9 0.089 12.1 4.1 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Cdc6_C PF09079.6 EKE38230.1 - 0.095 12.4 0.7 0.18 11.5 0.1 1.7 2 0 0 2 2 2 0 CDC6, C terminal NPV_P10 PF05531.7 EKE38230.1 - 0.13 12.5 4.8 0.17 12.1 3.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GvpK PF05121.7 EKE38230.1 - 0.13 12.0 5.1 0.22 11.3 0.4 2.0 1 1 1 2 2 2 0 Gas vesicle protein K DUF3890 PF13029.1 EKE38230.1 - 0.27 11.2 2.7 0.44 10.6 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) DUF4600 PF15372.1 EKE38230.1 - 0.32 11.2 7.1 0.38 10.9 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Lipoprotein_20 PF13942.1 EKE38230.1 - 0.81 9.1 8.3 0.99 8.9 5.8 1.1 1 0 0 1 1 1 0 YfhG lipoprotein DUF342 PF03961.8 EKE38230.1 - 0.9 7.8 5.6 0.93 7.8 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EKE38230.1 - 1.3 8.8 4.3 1.7 8.4 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 EKE38230.1 - 1.6 8.6 12.8 12 5.8 8.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EKE38230.1 - 1.6 6.4 5.2 1.6 6.4 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EKE38230.1 - 3.5 7.3 9.5 5.9 6.6 6.6 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 LRR_5 PF13306.1 EKE38231.1 - 4.8e-24 84.5 1.7 4.8e-24 84.5 1.2 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38231.1 - 1.2e-09 37.8 0.4 5.2e-07 29.3 0.2 2.7 2 0 0 2 2 2 2 Leucine rich repeat Sec1 PF00995.18 EKE38232.1 - 1.9e-21 76.3 16.7 3.6e-16 58.9 11.2 3.0 2 1 0 2 2 2 2 Sec1 family EssA PF10661.4 EKE38233.1 - 0.02 14.5 1.0 0.022 14.4 0.7 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF3757 PF12582.3 EKE38237.1 - 0.005 17.0 1.1 0.028 14.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3757) Metallophos PF00149.23 EKE38238.1 - 0.004 16.5 0.6 0.067 12.5 0.4 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1700 PF08006.6 EKE38238.1 - 0.011 15.0 2.0 0.011 15.0 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) VWA_2 PF13519.1 EKE38239.1 - 4.4e-09 36.6 0.0 7.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE38239.1 - 0.00011 21.9 1.1 0.0002 21.1 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Ku_N PF03731.10 EKE38239.1 - 0.0085 15.5 0.4 0.59 9.5 0.0 2.8 2 2 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Xpo1 PF08389.7 EKE38239.1 - 0.013 15.3 0.3 0.15 12.0 0.1 2.6 2 2 0 2 2 2 0 Exportin 1-like protein Lectin_N PF03954.9 EKE38239.1 - 0.054 12.8 0.1 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Brix PF04427.13 EKE38241.1 - 8.9e-38 129.8 0.6 1.4e-37 129.1 0.4 1.3 1 0 0 1 1 1 1 Brix domain HVSL PF09749.4 EKE38242.1 - 1e-21 77.0 2.4 3.6e-21 75.2 1.7 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 EKE38242.1 - 0.00075 19.2 0.2 0.0017 18.0 0.0 1.6 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Syntaxin-6_N PF09177.6 EKE38243.1 - 0.0057 17.0 5.5 0.045 14.1 3.9 2.5 1 1 0 1 1 1 1 Syntaxin 6, N-terminal TLD PF07534.11 EKE38243.1 - 0.19 11.6 12.4 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 TLD Pkinase_Tyr PF07714.12 EKE38244.1 - 7.1e-49 166.2 0.0 1.1e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38244.1 - 3.1e-41 141.2 0.0 5.4e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain hEGF PF12661.2 EKE38244.1 - 0.13 12.3 12.1 0.43 10.7 1.3 4.5 4 0 0 4 4 4 0 Human growth factor-like EGF Baculo_11_kDa PF06143.6 EKE38244.1 - 8.9 5.7 7.5 22 4.5 5.2 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family FGGY_N PF00370.16 EKE38245.1 - 1.8e-52 178.0 0.0 2.5e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EKE38245.1 - 9.9e-09 35.0 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CN_hydrolase PF00795.17 EKE38246.1 - 4.9e-13 48.8 0.1 7.6e-13 48.2 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase RNase_P_Rpp14 PF01900.14 EKE38246.1 - 0.099 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rpp14/Pop5 family Rhomboid PF01694.17 EKE38247.1 - 1.9e-18 66.9 16.6 1.9e-18 66.9 11.5 1.7 2 0 0 2 2 2 1 Rhomboid family SAC3 PF12209.3 EKE38247.1 - 0.0089 16.1 0.6 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain Syntaxin PF00804.20 EKE38248.1 - 1.4 9.1 8.8 0.37 10.9 1.6 2.4 2 0 0 2 2 2 0 Syntaxin Pkinase PF00069.20 EKE38249.1 - 1.1e-87 293.4 4.0 7.1e-54 182.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38249.1 - 1.9e-56 190.9 0.2 3.9e-32 111.3 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKE38249.1 - 0.00073 18.5 0.0 0.33 9.8 0.0 2.5 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EKE38249.1 - 0.061 13.0 0.0 1.9 8.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rrp15p PF07890.7 EKE38250.1 - 2.2e-15 56.8 10.2 2.2e-15 56.8 7.1 2.6 1 1 1 2 2 2 1 Rrp15p Peptidase_C1 PF00112.18 EKE38251.1 - 2.4e-76 256.4 2.3 3.1e-76 256.0 1.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE38251.1 - 9e-07 29.0 4.3 1.6e-06 28.2 3.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKE38251.1 - 0.00054 18.5 0.9 0.0075 14.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family E1-E2_ATPase PF00122.15 EKE38253.1 - 6.1e-23 81.0 0.0 6.1e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKE38253.1 - 3.4e-15 57.0 0.1 8.2e-14 52.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE38253.1 - 9.5e-13 48.7 0.0 2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE38253.1 - 5.1e-11 42.3 0.3 2e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKE38253.1 - 0.011 15.3 3.8 0.038 13.5 1.2 2.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ACPS PF01648.15 EKE38254.1 - 5.6e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Tetraspannin PF00335.15 EKE38255.1 - 0.0011 18.2 19.7 0.0032 16.7 13.6 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF3810 PF12725.2 EKE38255.1 - 0.026 13.4 0.5 0.026 13.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Papilloma_E5A PF05776.7 EKE38255.1 - 8.2 6.6 11.1 1.6 8.9 3.9 2.0 2 0 0 2 2 2 0 Papillomavirus E5A protein DUF3328 PF11807.3 EKE38255.1 - 8.6 5.9 5.8 9.6 5.8 0.1 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF3328) CD20 PF04103.10 EKE38255.1 - 9.2 6.1 15.5 27 4.6 10.7 1.7 1 1 0 1 1 1 0 CD20-like family DUF4600 PF15372.1 EKE38256.1 - 0.0022 18.2 0.4 0.004 17.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) MLANA PF14991.1 EKE38256.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DUF4006 PF13179.1 EKE38256.1 - 0.053 13.0 1.0 0.11 12.0 0.6 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF4006) Myb_DNA-binding PF00249.26 EKE38258.1 - 7.4e-28 96.3 3.0 1.2e-13 50.8 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE38258.1 - 1.9e-23 82.3 8.6 6.5e-14 51.7 2.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 EKE38258.1 - 0.0012 18.5 0.4 1.2 8.8 0.0 2.5 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.6 EKE38258.1 - 0.0018 18.0 3.0 4 7.3 0.1 3.6 1 1 1 2 2 2 2 Rap1 Myb domain DUF4085 PF13315.1 EKE38258.1 - 0.052 12.9 3.4 1.5 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) PRKCSH-like PF12999.2 EKE38259.1 - 2.5e-05 23.9 7.8 2.5e-05 23.9 5.4 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EKE38259.1 - 0.017 14.5 1.0 0.017 14.5 0.7 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Adeno_E3_CR1 PF02440.10 EKE38259.1 - 0.017 14.5 1.7 0.067 12.6 0.9 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 DUF2443 PF10398.4 EKE38259.1 - 2.1 8.2 7.7 0.41 10.4 0.4 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) DUF381 PF04038.7 EKE38260.1 - 0.048 13.6 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF381) DUF2175 PF09943.4 EKE38260.1 - 0.27 11.3 5.7 0.7 9.9 1.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2HC5 PF06221.8 EKE38260.1 - 1.3 8.8 7.0 3 7.6 0.1 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Cofilin_ADF PF00241.15 EKE38261.1 - 5.3e-16 58.6 0.0 6.3e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Gryzun-like PF12742.2 EKE38262.1 - 5.9e-08 32.4 0.0 1.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.3 EKE38262.1 - 0.0005 19.6 0.0 0.0014 18.1 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 WD40 PF00400.27 EKE38264.1 - 4e-32 108.9 28.9 2.9e-11 42.7 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EKE38264.1 - 1.3e-06 26.8 4.9 0.034 12.2 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 ATG16 PF08614.6 EKE38264.1 - 0.00089 19.1 14.9 0.0016 18.2 10.3 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Rab5-bind PF09311.6 EKE38264.1 - 0.0016 18.3 13.4 0.036 13.9 4.8 2.2 1 1 1 2 2 2 2 Rabaptin-like protein zf-C4H2 PF10146.4 EKE38264.1 - 0.003 17.6 9.1 0.005 16.9 6.3 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein PQQ_2 PF13360.1 EKE38264.1 - 0.017 14.5 0.3 2.3 7.6 0.0 2.9 2 1 0 3 3 3 0 PQQ-like domain NUDE_C PF04880.8 EKE38264.1 - 0.037 14.3 4.6 0.026 14.8 1.6 1.8 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Kelch_6 PF13964.1 EKE38264.1 - 0.056 13.6 0.1 0.37 11.0 0.0 2.4 3 0 0 3 3 2 0 Kelch motif YqgF PF14639.1 EKE38264.1 - 0.18 11.3 8.8 3.4 7.2 5.2 2.4 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 APG6 PF04111.7 EKE38264.1 - 2.7 6.9 18.8 6.2 5.7 7.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EKE38264.1 - 3.5 5.3 8.5 4.9 4.8 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Synaptobrevin PF00957.16 EKE38265.1 - 3.4e-10 39.3 0.4 1.1e-09 37.7 0.3 1.9 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EKE38265.1 - 2.7e-09 36.4 0.3 4.4e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Corona_S2 PF01601.11 EKE38265.1 - 0.0076 14.4 1.2 0.017 13.2 0.0 1.8 1 1 1 2 2 2 1 Coronavirus S2 glycoprotein Rifin_STEVOR PF02009.11 EKE38265.1 - 0.038 13.6 2.4 0.16 11.5 1.3 1.9 1 1 1 2 2 2 0 Rifin/stevor family Seryl_tRNA_N PF02403.17 EKE38265.1 - 0.055 13.4 7.0 0.16 11.9 0.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tup_N PF08581.5 EKE38265.1 - 0.29 11.3 0.2 0.29 11.3 0.1 2.2 3 0 0 3 3 3 0 Tup N-terminal TMF_DNA_bd PF12329.3 EKE38265.1 - 0.3 10.9 9.0 1.1 9.1 0.9 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tmemb_9 PF05434.6 EKE38265.1 - 0.38 10.4 2.9 0.2 11.3 0.2 1.9 2 0 0 2 2 2 0 TMEM9 DUF4097 PF13349.1 EKE38265.1 - 1.7 8.1 7.4 0.39 10.2 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Ras PF00071.17 EKE38267.1 - 1.1e-44 151.7 0.5 1.3e-44 151.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38267.1 - 7.1e-18 65.2 0.1 9.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38267.1 - 6e-14 51.6 0.0 8.1e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE38267.1 - 7.8e-07 29.0 0.1 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE38267.1 - 4.7e-05 22.8 0.1 0.00025 20.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE38267.1 - 0.0017 17.5 0.1 0.0028 16.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE38267.1 - 0.0032 16.6 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EKE38267.1 - 0.0095 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 EKE38267.1 - 0.011 15.4 0.1 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EKE38267.1 - 0.015 14.7 0.1 0.051 13.0 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EKE38267.1 - 0.045 12.8 0.0 0.065 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EKE38267.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DIL PF01843.14 EKE38268.1 - 1.9e-08 34.0 0.6 1.9e-08 34.0 0.4 2.9 3 0 0 3 3 3 1 DIL domain Ribosomal_L29 PF00831.18 EKE38268.1 - 1.2 8.8 5.8 4.5 7.0 0.1 3.9 4 1 1 5 5 5 0 Ribosomal L29 protein Pkinase PF00069.20 EKE38269.1 - 1.3e-56 191.6 0.0 4.1e-56 190.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38269.1 - 2.5e-23 82.5 0.2 1.5e-22 79.9 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EKE38269.1 - 1.1e-07 31.3 0.2 1.9e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 EKE38269.1 - 0.0005 19.8 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKE38269.1 - 0.014 14.9 0.2 0.014 14.9 0.1 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase TMF_TATA_bd PF12325.3 EKE38270.1 - 0.018 14.7 11.6 0.031 13.9 8.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Hat1_N PF10394.4 EKE38270.1 - 0.027 14.5 7.7 0.033 14.2 5.3 1.2 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus DUF972 PF06156.8 EKE38270.1 - 0.14 12.4 16.4 0.12 12.7 10.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nairovirus_M PF07948.6 EKE38270.1 - 0.15 10.1 5.9 0.17 9.9 4.1 1.0 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DUF1843 PF08898.5 EKE38270.1 - 1 9.4 6.4 2.3 8.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF2935 PF11155.3 EKE38270.1 - 1.9 8.6 11.4 3.1 7.8 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) HDV_ag PF01517.13 EKE38270.1 - 5.7 6.5 8.9 43 3.6 5.1 2.1 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen APG6 PF04111.7 EKE38270.1 - 6.7 5.6 22.1 8 5.4 15.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EKE38270.1 - 7.3 4.8 15.5 8.7 4.6 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Inhibitor_I42 PF09394.5 EKE38271.1 - 1.9e-23 82.5 0.0 2.2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.2 EKE38271.1 - 0.015 14.9 0.1 0.066 12.8 0.0 1.8 1 1 1 2 2 2 0 Falstatin, cysteine peptidase inhibitor Peptidase_C1 PF00112.18 EKE38272.1 - 2.7e-71 239.9 3.5 4.5e-71 239.2 2.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE38272.1 - 1.8e-08 34.5 5.9 2.7e-08 33.9 3.3 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKE38272.1 - 1.6e-05 23.6 1.5 0.0034 15.9 0.1 2.3 2 1 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.1 EKE38272.1 - 0.022 15.1 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family DUF1039 PF06287.6 EKE38273.1 - 0.056 13.3 0.3 0.17 11.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) Borrelia_P83 PF05262.6 EKE38273.1 - 1.5 6.9 34.1 2.1 6.5 23.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 EKE38273.1 - 4.5 4.8 9.5 5.5 4.5 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NMT_C PF02799.10 EKE38274.1 - 2.1e-56 190.3 3.9 4.3e-56 189.3 2.7 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EKE38274.1 - 1.8e-55 186.9 0.1 1.8e-55 186.9 0.1 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EKE38274.1 - 0.00026 20.8 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKE38274.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family RecX PF02631.11 EKE38275.1 - 0.054 13.6 0.7 0.11 12.7 0.5 1.5 1 0 0 1 1 1 0 RecX family VPS9 PF02204.13 EKE38275.1 - 0.25 11.3 1.9 1.3 9.1 0.1 2.7 2 1 1 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain ARGLU PF15346.1 EKE38275.1 - 0.89 9.3 8.1 0.42 10.3 2.7 2.3 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 DUF948 PF06103.6 EKE38275.1 - 2.2 8.2 11.7 1.7 8.5 1.5 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3184 PF11380.3 EKE38276.1 - 0.1 10.5 0.2 0.23 9.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3184) PNTB PF02233.11 EKE38277.1 - 1.8e-13 50.1 0.8 1.8e-13 50.1 0.5 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit Na_Ca_ex PF01699.19 EKE38277.1 - 0.063 12.8 2.3 0.1 12.2 1.6 1.4 1 1 0 1 1 1 0 Sodium/calcium exchanger protein E1-E2_ATPase PF00122.15 EKE38277.1 - 0.17 10.8 0.7 0.18 10.8 0.5 1.2 1 0 0 1 1 1 0 E1-E2 ATPase FNIP_M PF14637.1 EKE38278.1 - 0.044 13.3 2.1 0.054 13.0 1.4 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Lzipper-MIP1 PF14389.1 EKE38278.1 - 1.1 9.3 8.7 0.92 9.6 1.6 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 RasGAP PF00616.14 EKE38279.1 - 0.0006 19.5 10.4 0.037 13.6 1.0 3.0 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase Microtub_assoc PF07989.6 EKE38279.1 - 0.12 12.2 4.1 0.33 10.7 2.8 1.8 1 0 0 1 1 1 0 Microtubule associated DSPc PF00782.15 EKE38280.1 - 4.2e-31 107.2 0.4 1.5e-30 105.4 0.0 2.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 EKE38280.1 - 2.5e-18 65.5 17.3 7.5e-10 38.4 0.4 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EKE38280.1 - 3.6e-16 58.3 22.0 2.7e-08 33.2 0.3 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EKE38280.1 - 2.4e-09 35.9 19.3 0.00081 19.0 0.6 5.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EKE38280.1 - 9.7e-07 28.0 19.8 0.0071 16.3 0.3 5.2 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 EKE38280.1 - 1.2e-05 24.8 23.5 0.22 11.6 0.4 5.4 4 1 1 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.1 EKE38280.1 - 7.4e-05 22.3 1.5 0.00013 21.5 1.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat Y_phosphatase PF00102.22 EKE38280.1 - 0.00041 19.7 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_5 PF13306.1 EKE38280.1 - 0.035 13.8 3.6 0.1 12.3 2.5 1.9 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) CDC45 PF02724.9 EKE38281.1 - 0.47 8.4 12.7 0.66 7.9 8.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1237 PF06824.6 EKE38282.1 - 0.48 8.9 3.7 0.88 8.1 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) BRO1 PF03097.13 EKE38284.1 - 6.5e-40 137.0 2.8 6.5e-40 137.0 1.9 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EKE38284.1 - 1.6e-28 99.5 19.1 4.1e-28 98.1 13.3 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Snapin_Pallidin PF14712.1 EKE38284.1 - 4.9 7.5 15.6 0.081 13.2 2.4 3.8 3 1 1 4 4 4 0 Snapin/Pallidin HrpJ PF07201.6 EKE38285.1 - 0.049 13.6 14.9 0.073 13.0 10.3 1.2 1 0 0 1 1 1 0 HrpJ-like domain TBPIP PF07106.8 EKE38285.1 - 0.41 10.1 39.4 0.021 14.3 19.2 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HAUS-augmin3 PF14932.1 EKE38285.1 - 0.88 8.6 28.0 0.51 9.4 13.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 ACR_tran PF00873.14 EKE38285.1 - 1.2 6.4 13.5 1.4 6.2 9.4 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF3492 PF11997.3 EKE38285.1 - 2.7 7.4 11.7 4.2 6.8 7.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) DUF932 PF06067.6 EKE38285.1 - 2.8 7.1 8.2 0.44 9.8 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF932) DUF883 PF05957.8 EKE38285.1 - 3.9 7.9 7.9 1.9 8.9 2.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2252 PF10009.4 EKE38285.1 - 4.4 6.1 9.3 5.3 5.8 6.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Cnd1 PF12717.2 EKE38285.1 - 8.7 6.1 16.1 29 4.4 11.2 2.1 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Pmp3 PF01679.12 EKE38286.1 - 9.4e-16 57.2 7.2 1.2e-15 56.9 5.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2142 PF09913.4 EKE38286.1 - 0.072 11.7 0.7 0.079 11.6 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) SdpI PF13630.1 EKE38286.1 - 0.1 12.3 4.0 0.12 12.0 2.8 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family Mpv17_PMP22 PF04117.7 EKE38286.1 - 0.1 12.2 0.5 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 Mpv17 / PMP22 family Prominin PF05478.6 EKE38286.1 - 0.15 9.5 0.7 0.21 9.0 0.5 1.3 1 0 0 1 1 1 0 Prominin EIF_2_alpha PF07541.7 EKE38287.1 - 1.2e-27 95.8 0.0 2.2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EKE38287.1 - 8.6e-07 28.9 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain UCH PF00443.24 EKE38288.1 - 4.5e-49 166.9 1.7 5.8e-49 166.6 1.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE38288.1 - 6.3e-17 61.9 3.4 3.4e-11 43.1 0.3 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PINIT PF14324.1 EKE38289.1 - 0.052 13.6 1.8 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 PINIT domain Herpes_BLRF2 PF05812.7 EKE38289.1 - 0.071 12.9 0.3 0.071 12.9 0.2 3.1 3 1 0 3 3 3 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EKE38289.1 - 0.11 12.4 9.1 1.9 8.4 0.6 3.0 1 1 1 2 2 2 0 bZIP transcription factor HALZ PF02183.13 EKE38289.1 - 1 9.1 8.2 2.2 8.0 1.1 3.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper Synaptobrevin PF00957.16 EKE38290.1 - 2.8e-27 94.1 8.3 3.9e-27 93.6 5.8 1.2 1 0 0 1 1 1 1 Synaptobrevin VIT1 PF01988.14 EKE38290.1 - 0.00078 18.9 0.2 0.0011 18.4 0.1 1.1 1 0 0 1 1 1 1 VIT family GP41 PF00517.12 EKE38290.1 - 0.0013 18.3 5.8 0.0014 18.2 3.6 1.3 1 1 0 1 1 1 1 Retroviral envelope protein Rifin_STEVOR PF02009.11 EKE38290.1 - 0.0017 18.0 3.5 0.0021 17.7 2.5 1.1 1 0 0 1 1 1 1 Rifin/stevor family Corona_S2 PF01601.11 EKE38290.1 - 0.004 15.3 2.1 0.0047 15.0 1.4 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein DUF3753 PF12575.3 EKE38290.1 - 0.0054 16.5 1.0 0.015 15.1 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) DUF4199 PF13858.1 EKE38290.1 - 0.0069 16.3 0.4 0.0069 16.3 0.3 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF4199) DUF912 PF06024.7 EKE38290.1 - 0.0085 16.1 0.9 0.0085 16.1 0.6 1.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) EVI2A PF05399.6 EKE38290.1 - 0.014 14.6 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) TraG_N PF07916.6 EKE38290.1 - 0.015 13.7 0.0 0.016 13.6 0.0 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region T2SF PF00482.18 EKE38290.1 - 0.017 15.0 0.8 0.028 14.3 0.5 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Fzo_mitofusin PF04799.8 EKE38290.1 - 0.022 14.1 2.7 0.033 13.5 1.8 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4635 PF15466.1 EKE38290.1 - 0.025 13.8 2.4 0.044 13.0 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) Mem_trans PF03547.13 EKE38290.1 - 0.029 12.6 0.5 0.034 12.4 0.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Rhabdo_glycop PF00974.13 EKE38290.1 - 0.036 12.3 0.4 0.036 12.3 0.3 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein RskA PF10099.4 EKE38290.1 - 0.06 13.0 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2890 PF11081.3 EKE38290.1 - 0.066 13.2 7.0 0.089 12.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF740 PF05340.7 EKE38290.1 - 0.077 11.3 3.0 0.094 11.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF2937 PF11157.3 EKE38290.1 - 0.079 12.2 0.5 0.14 11.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) DUF2077 PF09850.4 EKE38290.1 - 0.15 11.4 0.2 0.24 10.8 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Snapin_Pallidin PF14712.1 EKE38290.1 - 0.2 12.0 5.3 0.16 12.3 2.6 1.5 1 1 0 1 1 1 0 Snapin/Pallidin EMP24_GP25L PF01105.19 EKE38290.1 - 0.41 10.3 5.3 0.63 9.7 3.7 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2951 PF11166.3 EKE38290.1 - 0.5 10.2 13.8 2.1 8.2 9.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) CRT-like PF08627.5 EKE38290.1 - 0.58 10.0 3.7 0.37 10.7 1.3 1.6 1 1 0 1 1 1 0 CRT-like DUF607 PF04678.8 EKE38290.1 - 1.1 9.1 4.2 1.7 8.5 2.9 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF2839 PF10999.3 EKE38290.1 - 1.1 9.3 4.7 0.27 11.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) XhlA PF10779.4 EKE38290.1 - 2 8.3 21.1 0.19 11.6 5.9 2.5 1 1 1 2 2 2 0 Haemolysin XhlA DUF1191 PF06697.7 EKE38290.1 - 3.4 6.3 7.3 0.73 8.5 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1191) Nol1_Nop2_Fmu PF01189.12 EKE38291.1 - 1.2e-41 142.9 0.0 1.3e-21 77.2 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EKE38291.1 - 9.6e-07 28.9 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EKE38291.1 - 0.0085 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EKE38291.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EKE38291.1 - 0.013 14.5 0.0 0.083 11.9 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EKE38291.1 - 0.14 12.5 0.1 0.34 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain K-box PF01486.12 EKE38293.1 - 1.5 8.6 5.1 18 5.1 0.2 3.4 3 0 0 3 3 3 0 K-box region RasGEF PF00617.14 EKE38294.1 - 5.5e-05 22.9 0.1 0.0029 17.3 0.1 2.6 1 1 0 1 1 1 1 RasGEF domain Peptidase_M26_N PF05342.9 EKE38296.1 - 0.085 11.8 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region UBA PF00627.26 EKE38298.1 - 5.9e-10 38.6 0.8 3e-09 36.4 0.4 2.3 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.18 EKE38298.1 - 8e-10 37.9 0.0 1.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EKE38298.1 - 0.00039 20.5 0.0 0.0007 19.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EKE38298.1 - 0.0016 18.0 0.1 0.022 14.4 0.0 2.4 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EKE38298.1 - 0.014 14.9 0.5 0.14 11.6 0.1 2.6 2 0 0 2 2 2 0 CUE domain Rad60-SLD_2 PF13881.1 EKE38298.1 - 0.032 14.1 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pox_A3L PF05288.6 EKE38298.1 - 0.79 9.4 2.6 2.7 7.7 0.4 2.9 3 1 1 4 4 4 0 Poxvirus A3L Protein IF-2B PF01008.12 EKE38299.1 - 0.025 13.5 0.1 0.031 13.2 0.1 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family LIM PF00412.17 EKE38300.1 - 1e-60 201.6 35.1 1.2e-15 57.3 0.6 4.2 4 0 0 4 4 4 4 LIM domain DUF3725 PF12523.3 EKE38300.1 - 0.01 15.9 4.0 6 7.0 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3725) Ribosomal_L40e PF01020.12 EKE38300.1 - 0.039 13.5 0.1 0.039 13.5 0.1 6.6 5 3 3 8 8 8 0 Ribosomal L40e family FUSC PF04632.7 EKE38300.1 - 0.062 11.7 0.2 0.43 8.9 0.0 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1631 PF07793.6 EKE38300.1 - 0.29 9.1 6.0 0.43 8.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF572 PF04502.8 EKE38300.1 - 0.35 10.0 8.7 0.84 8.7 6.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) FKBP_N PF01346.13 EKE38300.1 - 1.2 9.2 7.5 0.34 10.9 2.1 2.3 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase AAA_13 PF13166.1 EKE38300.1 - 3.4 6.0 13.9 5.7 5.2 0.1 3.1 2 1 1 3 3 3 0 AAA domain AAA_10 PF12846.2 EKE38300.1 - 7.1 5.9 8.2 13 5.0 5.7 1.5 1 1 0 1 1 1 0 AAA-like domain DnaJ PF00226.26 EKE38301.1 - 8.5e-26 89.4 2.6 1.4e-25 88.8 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EKE38301.1 - 2.1e-23 82.0 2.8 8.3e-21 73.6 0.0 3.8 3 1 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKE38301.1 - 7.7e-14 51.4 19.7 1.3e-13 50.7 13.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EKE38301.1 - 0.41 10.3 11.5 0.13 11.9 0.8 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EKE38301.1 - 0.59 10.4 10.0 13 6.1 6.9 2.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.2 EKE38301.1 - 3.7 7.4 13.7 44 3.9 9.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon Haem_bd PF14376.1 EKE38301.1 - 4.9 6.8 7.6 4.9 6.8 0.4 3.2 3 0 0 3 3 3 0 Haem-binding domain Zn-ribbon_8 PF09723.5 EKE38301.1 - 5.7 6.9 15.6 2.4 8.1 2.6 3.9 1 1 3 4 4 4 0 Zinc ribbon domain PWWP PF00855.12 EKE38302.1 - 4.4e-17 62.0 2.7 4.4e-17 62.0 1.8 2.3 1 1 1 2 2 2 1 PWWP domain FKBP_N PF01346.13 EKE38302.1 - 0.078 13.0 1.5 0.16 12.0 1.1 1.6 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ras PF00071.17 EKE38303.1 - 8.3e-06 25.2 0.1 1.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EKE38303.1 - 0.023 14.6 0.0 0.06 13.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE38303.1 - 0.028 13.7 0.4 6.4 6.0 0.1 2.6 2 1 1 3 3 3 0 Ferrous iron transport protein B Tol_Tol_Ttg2 PF05494.7 EKE38303.1 - 0.048 13.2 1.3 0.083 12.4 0.0 2.0 2 1 1 3 3 3 0 Toluene tolerance, Ttg2 Miro PF08477.8 EKE38303.1 - 0.31 11.5 3.6 0.84 10.1 0.3 2.7 2 1 0 2 2 2 0 Miro-like protein Tetraspannin PF00335.15 EKE38304.1 - 0.24 10.6 12.0 1.3 8.1 8.3 1.8 1 1 0 1 1 1 0 Tetraspanin family YIF1 PF03878.10 EKE38305.1 - 3.2e-16 59.2 9.1 4e-16 58.9 6.3 1.1 1 0 0 1 1 1 1 YIF1 Corona_M PF01635.13 EKE38305.1 - 4.8 6.0 11.1 1 8.2 4.8 2.0 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Nol1_Nop2_Fmu PF01189.12 EKE38306.1 - 5.1e-24 85.1 0.0 1.9e-13 50.4 0.0 3.1 3 0 0 3 3 3 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EKE38306.1 - 9.9e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKE38306.1 - 0.00079 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 EKE38306.1 - 0.0068 15.4 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 EKE38306.1 - 0.088 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Myotub-related PF06602.9 EKE38307.1 - 7.6e-56 189.3 2.9 9.9e-54 182.4 2.0 2.2 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain PP2C PF00481.16 EKE38308.1 - 1.5e-42 145.7 0.1 1.1e-27 97.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C LRR_4 PF12799.2 EKE38308.1 - 5e-39 131.3 105.8 2.8e-06 26.8 0.3 14.7 5 4 10 16 16 16 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE38308.1 - 5.8e-27 93.2 87.4 2.3e-08 33.6 3.8 10.5 4 3 6 11 11 11 9 Leucine rich repeat LRR_1 PF00560.28 EKE38308.1 - 7.1e-08 31.4 106.2 0.3 11.2 1.2 20.7 20 2 1 21 21 21 8 Leucine Rich Repeat LRR_5 PF13306.1 EKE38308.1 - 2e-05 24.2 8.7 2e-05 24.2 6.0 5.4 2 2 1 4 4 4 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EKE38308.1 - 0.0016 18.3 71.4 2.2 8.8 1.4 18.8 19 3 2 21 21 21 1 Leucine rich repeat PP2C_2 PF13672.1 EKE38308.1 - 0.0077 15.6 0.0 0.018 14.4 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_9 PF14580.1 EKE38308.1 - 0.01 15.3 19.9 0.11 12.0 0.0 4.9 2 2 4 6 6 6 0 Leucine-rich repeat Apis_Csd PF11671.3 EKE38308.1 - 2.2 8.0 4.3 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Complementary sex determiner protein MFS_1 PF07690.11 EKE38309.1 - 3.9e-25 88.3 38.6 1.1e-23 83.5 25.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKE38309.1 - 7e-11 41.3 18.7 1.3e-08 33.9 11.8 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EKE38309.1 - 4.1e-05 21.9 5.2 4.1e-05 21.9 3.6 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EKE38309.1 - 0.0015 16.9 2.0 0.0015 16.9 1.4 3.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EKE38309.1 - 0.0038 15.3 1.1 0.66 8.0 0.1 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector DUF3328 PF11807.3 EKE38309.1 - 0.09 12.4 1.3 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Herpes_gE PF02480.11 EKE38309.1 - 0.13 10.5 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ATG22 PF11700.3 EKE38310.1 - 0.0048 15.4 0.2 0.0057 15.1 0.2 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF2895 PF11444.3 EKE38310.1 - 0.005 16.0 2.1 0.008 15.4 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2895) DUF2324 PF10086.4 EKE38310.1 - 0.029 13.5 0.7 0.049 12.8 0.5 1.4 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) DUF3573 PF12097.3 EKE38310.1 - 0.94 8.0 8.1 1.5 7.3 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Alpha_kinase PF02816.13 EKE38311.1 - 3.2e-31 108.4 12.7 1.3e-29 103.1 8.8 2.5 1 1 0 1 1 1 1 Alpha-kinase family N6-adenineMlase PF10237.4 EKE38312.1 - 3e-44 150.5 1.6 4e-44 150.1 1.1 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 EKE38312.1 - 0.061 12.7 0.1 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF43 PF01861.11 EKE38312.1 - 0.074 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF43 AAA PF00004.24 EKE38313.1 - 1.7e-41 141.4 0.0 4.2e-39 133.7 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKE38313.1 - 1.7e-06 28.2 0.5 0.00058 20.0 0.1 3.6 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EKE38313.1 - 6.6e-06 25.3 0.0 1.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKE38313.1 - 1.7e-05 25.6 0.7 0.0011 19.7 0.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EKE38313.1 - 4.5e-05 23.3 0.0 0.0016 18.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 EKE38313.1 - 4.9e-05 23.0 0.3 0.00035 20.3 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.1 EKE38313.1 - 0.00014 21.7 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EKE38313.1 - 0.00018 20.9 0.0 0.00053 19.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EKE38313.1 - 0.00027 20.9 0.0 0.07 13.1 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EKE38313.1 - 0.00041 20.0 0.3 0.0017 18.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EKE38313.1 - 0.00083 18.9 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKE38313.1 - 0.0019 18.1 0.4 0.011 15.6 0.0 2.6 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EKE38313.1 - 0.0041 16.3 0.0 0.0097 15.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EKE38313.1 - 0.0041 16.5 1.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 EKE38313.1 - 0.017 15.4 0.0 0.017 15.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain TIP49 PF06068.8 EKE38313.1 - 0.02 13.6 0.1 0.02 13.6 0.1 2.4 2 1 1 3 3 3 0 TIP49 C-terminus AAA_28 PF13521.1 EKE38313.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EKE38313.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EKE38313.1 - 0.044 12.8 0.1 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EKE38313.1 - 0.046 13.8 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA_19 PF13245.1 EKE38313.1 - 0.048 13.4 0.1 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EKE38313.1 - 0.055 12.8 0.3 0.41 10.0 0.2 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EKE38313.1 - 0.071 12.5 0.0 0.2 11.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Turandot PF07240.6 EKE38313.1 - 0.074 12.5 0.1 1.5 8.3 0.0 2.7 3 0 0 3 3 2 0 Stress-inducible humoral factor Turandot His_Phos_2 PF00328.17 EKE38315.1 - 4.2e-32 111.8 0.0 5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EKE38315.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) GTP-bdg_N PF13167.1 EKE38315.1 - 0.11 12.5 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal Abhydrolase_5 PF12695.2 EKE38316.1 - 3.3e-08 33.3 0.0 5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE38316.1 - 7.9e-05 22.6 0.0 0.0043 16.9 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF3530 PF12048.3 EKE38316.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) SAM_1 PF00536.25 EKE38316.1 - 0.037 14.2 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EKE38316.1 - 0.045 13.6 0.1 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Abhydrolase_3 PF07859.8 EKE38316.1 - 0.074 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKE38316.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zf-MIZ PF02891.15 EKE38317.1 - 2.2e-07 30.2 9.0 5.2e-07 29.0 6.2 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EKE38317.1 - 3.7e-05 23.1 4.9 3.8e-05 23.1 1.2 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Cnd1 PF12717.2 EKE38318.1 - 2.9e-51 173.8 13.8 2.5e-50 170.8 0.0 4.3 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EKE38318.1 - 4.6e-12 46.0 0.0 2.6e-05 24.4 0.0 5.5 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.17 EKE38318.1 - 2.1e-06 27.3 0.7 1 9.6 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Cohesin_HEAT PF12765.2 EKE38318.1 - 0.0006 19.7 3.4 0.56 10.2 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EKE38318.1 - 0.0019 18.6 0.9 6.6 7.3 0.0 5.5 5 1 0 5 5 5 1 HEAT-like repeat DNA_alkylation PF08713.6 EKE38319.1 - 9e-54 182.2 0.0 1.1e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme Cnd1 PF12717.2 EKE38319.1 - 0.0026 17.6 4.8 0.075 12.8 0.0 2.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Katanin_con80 PF13925.1 EKE38319.1 - 0.09 12.5 1.6 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 con80 domain of Katanin HTH_26 PF13443.1 EKE38319.1 - 0.092 12.9 0.1 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TPR_12 PF13424.1 EKE38320.1 - 0.025 14.5 3.5 3.4 7.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EKE38320.1 - 0.22 11.6 6.3 4.3 7.5 0.0 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SNF2_N PF00176.18 EKE38321.1 - 4.5e-30 104.4 0.3 4.5e-30 104.4 0.2 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE38321.1 - 4.3e-10 39.3 0.1 1.5e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE38321.1 - 3.1e-06 27.1 0.0 3.1e-06 27.1 0.0 4.5 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Aft1_OSA PF11785.3 EKE38321.1 - 0.0094 16.4 0.1 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain GLYCAM-1 PF05242.6 EKE38322.1 - 0.07 13.0 16.3 0.16 11.8 10.6 2.1 1 1 1 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) malic PF00390.14 EKE38323.1 - 0.072 12.6 0.3 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain NAP PF00956.13 EKE38324.1 - 3.9e-19 68.7 3.0 4.7e-17 61.9 2.1 2.0 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) zf-RING_5 PF14634.1 EKE38325.1 - 0.019 14.6 11.3 0.019 14.6 7.8 4.0 3 1 1 4 4 4 0 zinc-RING finger domain C2 PF00168.25 EKE38326.1 - 1.6e-15 56.6 0.1 2.9e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 C2 domain TLD PF07534.11 EKE38326.1 - 0.026 14.4 2.1 0.059 13.3 1.5 1.6 1 1 0 1 1 1 0 TLD RRM_6 PF14259.1 EKE38327.1 - 4.7e-18 64.9 0.2 5.1e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE38327.1 - 6.5e-17 60.9 2.5 5.6e-12 45.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE38327.1 - 4.8e-10 39.1 0.3 8.6e-05 22.3 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKE38327.1 - 6.9e-06 25.8 0.5 0.00013 21.8 0.1 2.1 2 0 0 2 2 2 1 RNA binding motif FTP PF07504.8 EKE38327.1 - 0.0035 16.7 0.0 0.0078 15.6 0.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif LIM PF00412.17 EKE38328.1 - 1.2e-22 79.7 27.1 6e-12 45.4 3.5 3.5 3 1 1 4 4 4 2 LIM domain DZR PF12773.2 EKE38328.1 - 8.5e-06 25.4 27.6 0.00082 19.1 1.8 4.0 1 1 2 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EKE38328.1 - 8.1e-05 21.6 7.3 8.1e-05 21.6 5.0 5.5 3 2 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EKE38328.1 - 0.00049 19.4 47.3 0.00076 18.8 5.6 5.6 4 2 1 5 5 5 2 zinc-ribbon domain MSA-2c PF12238.3 EKE38328.1 - 0.0071 16.0 1.0 0.011 15.3 0.7 1.4 1 0 0 1 1 1 1 Merozoite surface antigen 2c zf-C2H2 PF00096.21 EKE38328.1 - 0.11 12.9 0.1 0.11 12.9 0.1 6.1 8 0 0 8 8 8 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.1 EKE38328.1 - 0.16 11.6 0.1 0.16 11.6 0.1 6.3 6 1 0 6 6 6 0 Nudix N-terminal DUF3279 PF11682.3 EKE38328.1 - 0.29 10.7 0.1 0.29 10.7 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3279) ROS_MUCR PF05443.6 EKE38328.1 - 0.32 10.7 1.4 2.9 7.6 0.0 2.8 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein DUF605 PF04652.11 EKE38328.1 - 5 6.4 13.2 6.7 5.9 9.1 1.1 1 0 0 1 1 1 0 Vta1 like RVT_connect PF06815.8 EKE38329.1 - 0.37 10.6 0.1 0.37 10.6 0.1 2.5 2 1 1 3 3 3 0 Reverse transcriptase connection domain Ras PF00071.17 EKE38330.1 - 1.4e-15 57.0 0.0 1.7e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38330.1 - 1.7e-08 34.9 0.0 2.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKE38330.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EKE38330.1 - 0.017 14.7 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EKE38330.1 - 0.06 13.4 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CorA PF01544.13 EKE38331.1 - 6e-46 156.7 8.0 6e-46 156.7 5.5 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF3784 PF12650.2 EKE38331.1 - 0.023 14.6 2.0 0.023 14.6 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) PP2C PF00481.16 EKE38332.1 - 3.8e-65 219.7 0.0 2.6e-64 217.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE38332.1 - 1.3e-05 24.7 0.0 3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.12 EKE38333.1 - 5.7e-13 48.5 0.1 9.5e-13 47.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38333.1 - 2.4e-12 46.5 1.4 2.4e-12 46.5 1.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Kinase-like PF14531.1 EKE38333.1 - 0.018 14.0 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ribosomal_L19e PF01280.15 EKE38334.1 - 1e-50 171.3 7.2 1e-50 171.3 5.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L19e Thioredoxin PF00085.15 EKE38335.1 - 5.2e-34 116.0 7.3 5.3e-28 96.7 0.1 3.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EKE38335.1 - 9.3e-27 94.0 16.9 1.7e-13 50.7 1.3 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EKE38335.1 - 2.2e-06 27.8 1.9 2.7e-05 24.3 0.5 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKE38335.1 - 0.00028 20.9 5.1 0.0041 17.1 0.5 4.5 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EKE38335.1 - 0.014 15.3 0.1 0.081 12.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Clavanin PF05452.6 EKE38335.1 - 0.025 14.5 0.2 0.4 10.6 0.0 2.7 2 0 0 2 2 2 0 Clavanin GreA_GreB_N PF03449.10 EKE38335.1 - 0.041 13.9 0.6 0.11 12.5 0.4 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Thioredoxin_3 PF13192.1 EKE38335.1 - 0.048 13.4 0.1 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.6 EKE38335.1 - 0.055 13.3 0.0 0.66 9.9 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 EKE38335.1 - 0.45 10.5 4.4 0.74 9.8 0.2 2.7 2 0 0 2 2 2 0 Glutaredoxin TFIIA_gamma_N PF02268.11 EKE38336.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain zf-CCCH PF00642.19 EKE38337.1 - 1.4e-15 56.5 18.2 1e-07 31.4 4.2 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 EKE38337.1 - 1.8 8.2 5.6 10 5.8 0.5 2.4 1 1 1 2 2 2 0 LRV protein FeS4 cluster EF1G PF00647.14 EKE38338.1 - 1.7e-35 120.9 0.9 2.4e-35 120.4 0.1 1.5 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain Not3 PF04065.10 EKE38339.1 - 4.9e-48 163.4 32.3 4.9e-48 163.4 22.4 2.5 1 1 2 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EKE38339.1 - 2.6e-23 82.3 10.9 2.6e-23 82.3 7.5 3.5 2 1 1 3 3 3 1 NOT2 / NOT3 / NOT5 family DER1 PF04511.10 EKE38340.1 - 1.2e-30 106.4 18.8 1.5e-30 106.2 13.0 1.0 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 EKE38340.1 - 0.011 16.0 1.7 0.011 16.0 1.2 2.5 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) ATP_synt_H PF05493.8 EKE38340.1 - 0.22 11.6 3.6 0.24 11.4 0.2 2.5 2 1 1 3 3 3 0 ATP synthase subunit H Rhomboid PF01694.17 EKE38340.1 - 0.53 10.3 9.4 4.3 7.3 6.5 2.3 1 1 0 1 1 1 0 Rhomboid family Mod_r PF07200.8 EKE38341.1 - 0.038 13.9 11.3 0.072 13.0 7.9 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Psu PF07455.6 EKE38341.1 - 0.17 11.3 0.8 0.3 10.5 0.6 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) HAS-barrel PF09378.5 EKE38341.1 - 0.26 11.2 4.4 0.26 11.2 0.6 2.3 2 0 0 2 2 2 0 HAS barrel domain Atg14 PF10186.4 EKE38341.1 - 0.28 10.1 5.5 0.38 9.6 3.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EKE38341.1 - 2.9 7.4 11.9 5.3 6.5 8.2 1.5 1 1 0 1 1 1 0 IncA protein DUF2681 PF10883.3 EKE38341.1 - 9.1 6.5 9.0 15 5.8 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Alpha-amylase PF00128.19 EKE38342.1 - 3e-05 23.5 0.3 0.00045 19.7 0.0 2.0 2 0 0 2 2 2 2 Alpha amylase, catalytic domain zf-ZPR1 PF03367.8 EKE38346.1 - 2.7e-92 306.1 1.9 2.7e-47 159.9 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DZR PF12773.2 EKE38346.1 - 0.027 14.3 6.3 0.16 11.8 0.2 3.2 2 2 0 2 2 2 0 Double zinc ribbon TK PF00265.13 EKE38346.1 - 0.039 13.5 0.6 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Thymidine kinase HypA PF01155.14 EKE38346.1 - 0.24 11.0 3.2 8.8 6.0 0.1 2.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 EKE38346.1 - 7.2 6.3 8.2 18 5.1 0.6 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_S7e PF01251.13 EKE38347.1 - 2.2e-33 115.3 4.7 2.8e-33 115.0 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e CodY PF06018.9 EKE38347.1 - 0.019 14.2 0.2 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 CodY GAF-like domain Paramyxo_ncap PF00973.14 EKE38348.1 - 0.054 12.1 0.9 0.055 12.1 0.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein BUD22 PF09073.5 EKE38348.1 - 0.55 9.2 16.4 0.54 9.2 11.4 1.1 1 0 0 1 1 1 0 BUD22 Saw1 PF11561.3 EKE38348.1 - 1 8.7 5.1 1.4 8.2 3.5 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Pox_Ag35 PF03286.9 EKE38348.1 - 1.9 8.0 12.4 2.2 7.7 8.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_C12 PF01088.16 EKE38350.1 - 3.8e-55 186.3 0.2 1e-54 184.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Mmp37 PF09139.6 EKE38350.1 - 0.16 10.9 3.7 0.23 10.4 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 WD40 PF00400.27 EKE38351.1 - 9.8e-11 41.1 3.3 3.4e-06 26.7 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3150 PF11348.3 EKE38352.1 - 0.014 14.5 6.3 0.014 14.5 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) DUF4568 PF15132.1 EKE38352.1 - 0.31 10.2 4.0 0.45 9.6 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) XPG_I_2 PF12813.2 EKE38352.1 - 1.1 8.7 9.0 1.9 7.9 6.2 1.5 1 1 0 1 1 1 0 XPG domain containing DUF4407 PF14362.1 EKE38352.1 - 1.8 7.4 9.6 2.1 7.2 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TraG-D_C PF12696.2 EKE38353.1 - 0.012 15.4 0.6 0.012 15.4 0.4 1.8 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Stirrup PF09061.1 EKE38353.1 - 0.02 14.7 0.5 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Stirrup Fes1 PF08609.5 EKE38354.1 - 1.3e-05 25.5 5.6 4.5e-05 23.8 3.9 2.0 1 1 0 1 1 1 1 Nucleotide exchange factor Fes1 DUF4061 PF13270.1 EKE38354.1 - 0.0017 18.3 1.2 0.0032 17.5 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF3232 PF11554.3 EKE38354.1 - 0.027 14.3 1.3 0.099 12.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) Flagellin_N PF00669.15 EKE38354.1 - 0.1 12.4 0.5 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region AKAP95 PF04988.7 EKE38354.1 - 0.18 11.5 3.7 0.12 12.1 0.4 2.0 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF3836 PF12930.2 EKE38354.1 - 0.89 9.0 5.3 0.18 11.3 0.8 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF3836) Pkinase_Tyr PF07714.12 EKE38355.1 - 1.6e-51 174.8 0.0 4.2e-51 173.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38355.1 - 3.1e-48 164.2 0.0 6.1e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain VSP PF03302.8 EKE38355.1 - 9.6e-08 31.0 587.8 0.013 14.2 27.3 18.1 2 2 14 16 16 16 12 Giardia variant-specific surface protein OAD_gamma PF04277.8 EKE38355.1 - 6.6 7.1 2.8 11 6.4 1.9 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain APH PF01636.18 EKE38355.1 - 6.8 6.3 0.3 10 5.7 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EKE38356.1 - 2.7e-17 62.7 0.2 4.9e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38356.1 - 4e-14 52.3 0.1 7.8e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain VSP PF03302.8 EKE38356.1 - 1.9e-06 26.7 172.0 3.2e-05 22.7 26.3 6.8 1 1 3 4 4 4 3 Giardia variant-specific surface protein TMEM154 PF15102.1 EKE38356.1 - 0.011 15.4 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.7 EKE38356.1 - 0.043 13.8 0.2 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4381 PF14316.1 EKE38356.1 - 0.28 11.2 0.6 0.53 10.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ASFV_J13L PF05568.6 EKE38356.1 - 1.2 8.6 3.2 2.2 7.7 2.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Metallophos_2 PF12850.2 EKE38357.1 - 9.4e-24 84.0 0.0 1.1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EKE38357.1 - 1.3e-06 28.0 0.7 4.2e-05 23.0 0.1 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Cation_efflux PF01545.16 EKE38359.1 - 6.8e-37 127.0 10.4 8.3e-37 126.8 7.2 1.0 1 0 0 1 1 1 1 Cation efflux family SET_assoc PF11767.3 EKE38360.1 - 0.41 9.9 3.2 5.5 6.3 0.2 3.0 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated zf-Sec23_Sec24 PF04810.10 EKE38360.1 - 0.84 9.2 13.3 0.091 12.3 5.6 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger VSP PF03302.8 EKE38361.1 - 0.058 12.0 63.3 0.045 12.3 10.3 2.8 1 1 1 2 2 2 0 Giardia variant-specific surface protein Nucleoside_tran PF01733.13 EKE38364.1 - 0.012 14.7 2.2 0.016 14.3 1.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter NADH-u_ox-rdase PF10785.4 EKE38364.1 - 0.19 11.9 0.7 0.44 10.8 0.3 1.9 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Cullin PF00888.17 EKE38366.1 - 2.2e-50 171.8 21.5 2.2e-50 171.8 14.9 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EKE38366.1 - 9.3e-13 47.8 2.4 2.5e-12 46.4 1.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Wzz PF02706.10 EKE38366.1 - 0.089 12.6 1.4 0.55 10.0 0.0 2.5 3 0 0 3 3 3 0 Chain length determinant protein SpecificRecomb PF10136.4 EKE38367.1 - 0.0063 14.6 0.1 0.0077 14.3 0.1 1.1 1 0 0 1 1 1 1 Site-specific recombinase Ribosomal_S13 PF00416.17 EKE38367.1 - 5.6 7.4 9.4 9.4 6.7 0.0 3.5 3 1 0 3 3 3 0 Ribosomal protein S13/S18 Vps35 PF03635.12 EKE38368.1 - 1.5e-114 383.7 34.8 2.8e-114 382.9 24.1 1.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Hydrolase_6 PF13344.1 EKE38369.1 - 5.6e-19 67.9 0.0 9.7e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE38369.1 - 4.7e-09 35.8 0.0 1.5e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like tRNA-synt_2b PF00587.20 EKE38370.1 - 2.6e-57 193.1 0.1 4e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKE38370.1 - 2.8e-15 56.0 0.1 9.8e-15 54.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain Arf PF00025.16 EKE38372.1 - 9.7e-42 142.1 0.0 1.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EKE38372.1 - 1.2e-11 44.2 0.0 1.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38372.1 - 9.1e-08 32.6 0.0 1.3e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EKE38372.1 - 4.1e-07 29.0 1.2 2.4e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 EKE38372.1 - 0.00085 18.8 0.0 0.013 14.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE38372.1 - 0.00097 18.3 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE38372.1 - 0.0021 17.9 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE38372.1 - 0.021 13.9 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE38372.1 - 0.032 14.3 0.0 0.063 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EKE38372.1 - 0.16 11.4 0.0 5.3 6.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ank_2 PF12796.2 EKE38373.1 - 1.1e-33 115.4 4.6 3.2e-10 40.2 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EKE38373.1 - 6.6e-29 98.2 0.5 0.00013 21.5 0.0 8.2 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EKE38373.1 - 4.7e-27 93.3 1.1 1.3e-05 25.2 0.0 6.8 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE38373.1 - 1.5e-26 89.7 6.1 0.001 19.0 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EKE38373.1 - 1.2e-23 83.0 10.8 1.6e-06 28.4 0.1 7.3 4 3 3 7 7 7 5 Ankyrin repeats (many copies) RasGAP PF00616.14 EKE38373.1 - 0.00087 19.0 12.8 0.00087 19.0 8.9 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase GED PF02212.13 EKE38373.1 - 0.017 15.0 4.1 1.5 8.7 0.1 4.1 3 0 0 3 3 3 0 Dynamin GTPase effector domain PLDc PF00614.17 EKE38375.1 - 5e-20 70.6 1.9 4.5e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EKE38375.1 - 3.6e-15 55.8 6.2 3.8e-10 39.5 1.5 2.7 2 1 0 2 2 2 2 PLD-like domain Prophage_tail PF06605.6 EKE38376.1 - 0.021 13.7 5.5 0.026 13.4 3.8 1.1 1 0 0 1 1 1 0 Prophage endopeptidase tail DUF4162 PF13732.1 EKE38376.1 - 0.049 14.1 0.3 0.15 12.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4162) TBCA PF02970.11 EKE38376.1 - 0.055 13.5 0.8 0.42 10.7 0.2 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor A Phage_HK97_TLTM PF06120.6 EKE38376.1 - 0.064 12.5 1.8 0.12 11.6 1.2 1.5 1 1 0 1 1 1 0 Tail length tape measure protein SPATA24 PF15175.1 EKE38376.1 - 0.2 11.3 3.2 0.24 11.0 2.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF1359 PF07097.6 EKE38376.1 - 0.48 10.4 5.2 5.2 7.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) Ribosomal_L30 PF00327.15 EKE38377.1 - 4.9e-21 74.0 1.8 1.1e-20 72.8 1.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EKE38377.1 - 0.05 13.6 1.1 0.12 12.4 0.8 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Med7 PF05983.6 EKE38378.1 - 6e-16 58.6 6.9 1.1e-15 57.8 4.8 1.4 1 1 0 1 1 1 1 MED7 protein ApoLp-III PF07464.6 EKE38378.1 - 0.016 15.2 2.9 0.048 13.6 0.7 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Sec66 PF09802.4 EKE38378.1 - 0.025 13.9 2.1 0.051 12.9 1.5 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF4337 PF14235.1 EKE38378.1 - 0.077 12.8 1.0 0.1 12.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Med28 PF11594.3 EKE38378.1 - 0.41 10.9 3.3 2.2 8.5 2.3 2.0 1 1 0 1 1 1 0 Mediator complex subunit 28 RabGAP-TBC PF00566.13 EKE38379.1 - 1.9e-19 69.9 12.5 1.9e-19 69.9 8.7 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Shugoshin_N PF07558.6 EKE38380.1 - 6.2 6.6 8.0 3.7 7.3 0.3 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region RIO1 PF01163.17 EKE38381.1 - 9.4e-47 158.8 0.0 1.5e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EKE38381.1 - 6.7e-33 112.6 0.5 2e-32 111.1 0.3 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 EKE38381.1 - 7.8e-09 35.6 0.5 0.0014 18.4 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EKE38381.1 - 0.00063 18.8 0.3 0.13 11.3 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EKE38381.1 - 0.0083 15.7 0.3 0.039 13.5 0.1 2.0 2 1 0 2 2 2 1 Choline/ethanolamine kinase Ribosomal_L40e PF01020.12 EKE38382.1 - 1.5e-29 101.3 6.6 1.7e-29 101.1 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L40e family zf-CHY PF05495.7 EKE38382.1 - 0.039 14.1 1.4 0.048 13.8 1.0 1.1 1 0 0 1 1 1 0 CHY zinc finger Ras PF00071.17 EKE38386.1 - 1.3e-48 164.4 0.5 1.5e-48 164.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38386.1 - 6.9e-18 65.2 0.2 2.4e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE38386.1 - 1.2e-15 57.2 0.1 1.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE38386.1 - 1.2e-09 37.7 0.3 1.4e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE38386.1 - 2.3e-05 23.9 0.1 0.0002 20.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE38386.1 - 9.7e-05 22.3 0.0 0.00028 20.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EKE38386.1 - 0.0038 17.4 0.8 0.18 11.9 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol_E_B PF04042.11 EKE38386.1 - 0.013 14.7 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DUF848 PF05852.6 EKE38386.1 - 0.015 15.1 1.7 0.03 14.1 0.3 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1615 PF07759.7 EKE38386.1 - 0.015 14.0 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) PduV-EutP PF10662.4 EKE38386.1 - 0.016 14.7 0.2 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EDR1 PF14381.1 EKE38386.1 - 0.028 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 SRPRB PF09439.5 EKE38386.1 - 0.033 13.3 0.0 0.054 12.7 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EKE38386.1 - 0.04 13.7 0.1 0.46 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EKE38386.1 - 0.095 12.8 0.9 0.68 10.0 0.7 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKE38386.1 - 0.16 11.8 0.4 1.5 8.7 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EKE38386.1 - 0.28 9.8 4.9 4.9 5.7 0.1 2.9 1 1 2 3 3 3 0 G-protein alpha subunit DUF900 PF05990.7 EKE38387.1 - 9.9e-25 87.2 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 EKE38387.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKE38387.1 - 0.04 13.8 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE38387.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UbiA PF01040.13 EKE38387.1 - 1.2 8.2 8.9 0.21 10.7 3.5 1.6 1 1 0 1 1 1 0 UbiA prenyltransferase family FHA PF00498.21 EKE38388.1 - 0.00034 20.6 0.1 0.00084 19.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain PapC_N PF13954.1 EKE38388.1 - 0.32 10.5 3.4 0.34 10.4 0.9 1.9 1 1 1 2 2 2 0 PapC N-terminal domain Thioredoxin PF00085.15 EKE38389.1 - 2.2e-26 91.5 0.1 2.6e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE38389.1 - 2.6e-06 27.5 0.3 0.00038 20.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EKE38389.1 - 3.3e-06 27.0 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EKE38389.1 - 4.8e-05 23.2 0.1 0.00055 19.8 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKE38389.1 - 0.00024 21.1 0.1 0.0028 17.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 EKE38389.1 - 0.02 14.4 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Redoxin DUF4431 PF14485.1 EKE38390.1 - 0.092 12.3 0.4 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) PRA1 PF03208.14 EKE38390.1 - 2.9 7.2 14.3 4.7 6.5 9.9 1.3 1 1 0 1 1 1 0 PRA1 family protein DUF1356 PF07092.7 EKE38390.1 - 3.4 6.8 6.3 0.56 9.3 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) DUF2628 PF10947.3 EKE38390.1 - 4.4 7.1 8.2 20 4.9 5.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) zf-DHHC PF01529.15 EKE38391.1 - 2.5e-25 88.8 17.8 2.5e-25 88.8 12.4 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF3529 PF12046.3 EKE38392.1 - 0.081 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Pneumo_M2 PF07380.6 EKE38393.1 - 0.12 12.3 2.5 0.18 11.8 0.3 2.5 2 1 0 2 2 2 0 Pneumovirus M2 protein ER_lumen_recept PF00810.13 EKE38394.1 - 3.4e-54 183.3 15.8 3.4e-54 183.3 10.9 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EKE38394.1 - 0.0015 18.0 19.0 0.002 17.6 0.7 4.2 3 2 1 4 4 4 3 PQ loop repeat Chitin_synth_2 PF03142.10 EKE38395.1 - 4.2e-34 117.8 0.6 4.2e-34 117.8 0.4 2.8 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EKE38395.1 - 2e-13 50.5 12.6 2.1e-12 47.1 8.7 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKE38395.1 - 3.9e-12 46.4 0.0 6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EKE38395.1 - 0.0072 15.6 0.1 0.038 13.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 UCH PF00443.24 EKE38396.1 - 6.8e-45 153.2 1.7 6.8e-45 153.2 1.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE38396.1 - 3.1e-15 56.3 2.3 3.1e-15 56.3 1.6 3.1 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Spc97_Spc98 PF04130.8 EKE38397.1 - 5.8e-52 176.7 20.1 8.2e-52 176.2 13.9 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Erf4 PF10256.4 EKE38397.1 - 0.0035 17.1 1.5 0.3 10.9 0.1 3.0 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family Beach PF02138.13 EKE38398.1 - 2.5e-31 109.1 13.5 1.3e-30 106.7 9.3 2.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EKE38398.1 - 4.6e-05 23.2 0.9 0.00014 21.6 0.7 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DSPc PF00782.15 EKE38399.1 - 2e-14 53.2 0.0 3.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 EKE38399.1 - 2.5e-10 39.7 54.6 0.0037 16.8 1.7 7.7 1 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE38399.1 - 2.8e-09 36.5 48.3 0.0019 17.9 2.1 6.8 2 2 4 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EKE38399.1 - 5.6e-07 28.7 57.0 0.34 11.1 0.0 13.0 10 2 3 13 13 13 5 Leucine Rich Repeat LRR_7 PF13504.1 EKE38399.1 - 9.6e-07 28.0 44.1 6.6 7.4 0.0 12.0 12 0 0 12 12 12 5 Leucine rich repeat LRR_6 PF13516.1 EKE38399.1 - 2 8.7 59.5 1.1 9.5 0.2 11.9 11 1 0 11 11 11 0 Leucine Rich repeat NOT2_3_5 PF04153.13 EKE38400.1 - 2.7e-12 46.7 1.3 2.7e-12 46.7 0.9 2.0 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Pkinase PF00069.20 EKE38401.1 - 4.8e-22 78.3 0.0 1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EKE38401.1 - 1.3e-16 59.7 19.2 1.1e-05 25.1 0.1 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 EKE38401.1 - 3.2e-09 36.2 0.0 6.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE38401.1 - 0.0029 16.6 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Hira PF07569.6 EKE38401.1 - 0.005 16.0 0.3 0.21 10.7 0.0 3.2 2 1 1 3 3 3 1 TUP1-like enhancer of split PQQ_2 PF13360.1 EKE38401.1 - 0.018 14.4 0.1 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain GRAM PF02893.15 EKE38402.1 - 3e-06 26.6 0.3 9.2e-06 25.0 0.2 1.8 1 0 0 1 1 1 1 GRAM domain FerA PF08165.6 EKE38402.1 - 0.0086 15.7 0.3 0.03 13.9 0.2 1.9 1 0 0 1 1 1 1 FerA (NUC095) domain CENP-H PF05837.7 EKE38402.1 - 2.4 8.3 13.9 0.15 12.2 2.4 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Abhydrolase_6 PF12697.2 EKE38403.1 - 2.3e-23 83.2 0.0 3.8e-23 82.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE38403.1 - 2.5e-22 79.2 0.0 6.3e-22 77.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKE38403.1 - 3.5e-18 65.2 0.0 5.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EKE38403.1 - 5.1e-11 42.5 0.0 1e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKE38403.1 - 1.6e-06 27.5 0.2 0.0052 16.0 0.0 2.3 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EKE38403.1 - 7.2e-06 25.5 0.0 0.14 11.5 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 EKE38403.1 - 0.00024 20.4 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 EKE38403.1 - 0.00087 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal ABC2_membrane_3 PF12698.2 EKE38403.1 - 0.0076 15.3 0.6 0.011 14.7 0.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein PhoPQ_related PF10142.4 EKE38403.1 - 0.02 13.4 0.0 3.9 5.8 0.0 2.1 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.8 EKE38403.1 - 0.024 14.1 0.0 0.27 10.6 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EKE38403.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydantoinase_A PF01968.13 EKE38403.1 - 0.057 12.5 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Thioesterase PF00975.15 EKE38403.1 - 0.088 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain GTP_EFTU PF00009.22 EKE38405.1 - 1.7e-38 131.9 0.4 3.2e-38 131.0 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE38405.1 - 3.3e-06 27.0 1.3 1.1e-05 25.3 0.2 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EKE38405.1 - 1.1e-05 25.5 0.2 4.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain G-alpha PF00503.15 EKE38405.1 - 0.00026 19.8 4.7 0.0004 19.1 0.2 2.5 3 0 0 3 3 3 1 G-protein alpha subunit GTP_EFTU_D2 PF03144.20 EKE38405.1 - 0.00064 19.7 6.5 0.004 17.2 3.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.17 EKE38405.1 - 0.00064 19.1 0.2 0.0018 17.6 0.1 1.7 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38405.1 - 0.00073 20.0 1.2 0.0073 16.7 0.7 2.6 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKE38405.1 - 0.0015 17.6 1.7 0.0054 15.8 1.2 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE38405.1 - 0.004 16.3 2.3 0.064 12.4 0.3 2.5 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 EKE38405.1 - 0.011 15.3 2.7 0.035 13.7 1.9 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 AAA_33 PF13671.1 EKE38405.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain HBS1_N PF08938.5 EKE38405.1 - 0.018 15.1 0.4 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 HBS1 N-terminus Zeta_toxin PF06414.7 EKE38405.1 - 0.059 12.4 0.4 3.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EKE38405.1 - 0.077 12.7 4.2 0.16 11.6 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EKE38405.1 - 0.41 9.9 5.1 0.13 11.5 0.2 2.5 3 1 0 3 3 3 0 Ferrous iron transport protein B Pkinase PF00069.20 EKE38408.1 - 3.1e-08 33.0 0.0 5.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EKE38408.1 - 3.4e-06 26.6 1.7 0.081 13.0 0.1 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 EKE38408.1 - 1.6e-05 25.0 0.3 0.00015 21.9 0.1 2.3 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EKE38408.1 - 4e-05 23.9 0.2 0.058 13.8 0.0 2.6 2 0 0 2 2 2 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EKE38408.1 - 0.0014 18.5 0.2 0.15 12.0 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EKE38408.1 - 0.01 14.1 1.7 0.15 10.3 0.2 2.5 1 1 1 2 2 2 0 Adaptin N terminal region Pkinase_Tyr PF07714.12 EKE38408.1 - 0.069 12.2 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase UPF0128 PF03673.8 EKE38408.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) zf-MIZ PF02891.15 EKE38409.1 - 2.7e-16 58.7 0.2 4.6e-16 58.0 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EKE38409.1 - 4.3e-08 32.5 0.5 4.3e-08 32.5 0.4 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit AAA_18 PF13238.1 EKE38412.1 - 1.4e-09 38.3 0.4 1.6e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain dNK PF01712.14 EKE38412.1 - 7.2e-05 22.7 2.3 0.083 12.8 0.4 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.1 EKE38412.1 - 0.00096 19.9 1.3 0.01 16.6 0.9 2.3 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EKE38412.1 - 0.0017 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.1 EKE38412.1 - 0.0028 17.6 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EKE38412.1 - 0.0035 16.8 0.1 0.0063 16.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 EKE38412.1 - 0.022 14.4 0.1 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.9 EKE38412.1 - 0.03 13.3 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain DUF258 PF03193.11 EKE38412.1 - 0.06 12.5 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE38412.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EKE38412.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EKE38412.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 EKE38412.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EKE38412.1 - 0.22 10.9 0.9 0.31 10.4 0.4 1.5 2 1 0 2 2 2 0 AAA-like domain HIN PF02760.10 EKE38414.1 - 0.025 13.9 0.2 0.037 13.4 0.2 1.3 1 0 0 1 1 1 0 HIN-200/IF120x domain Epimerase PF01370.16 EKE38415.1 - 1.6e-55 188.0 0.0 2.1e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EKE38415.1 - 5.3e-28 96.7 0.3 9.2e-28 95.9 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EKE38415.1 - 3.3e-20 71.9 0.2 3.7e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EKE38415.1 - 2.9e-19 69.0 0.4 4e-16 58.7 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EKE38415.1 - 5.3e-14 51.7 0.2 1.4e-13 50.4 0.1 1.6 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EKE38415.1 - 7.3e-14 51.3 0.0 1.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EKE38415.1 - 8e-10 39.0 0.0 3.4e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EKE38415.1 - 2.9e-09 37.0 0.0 4.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKE38415.1 - 2e-05 24.3 0.0 3.8e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EKE38415.1 - 0.00041 19.6 0.1 0.62 9.2 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family DUF1132 PF06575.7 EKE38415.1 - 0.013 15.7 0.0 5.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) UDPG_MGDP_dh_N PF03721.9 EKE38415.1 - 0.02 14.2 0.1 0.067 12.5 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2608 PF11019.3 EKE38415.1 - 0.055 12.4 0.4 0.095 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Cnd1 PF12717.2 EKE38416.1 - 1.7 8.4 9.3 0.49 10.2 2.0 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Apc5 PF12862.2 EKE38417.1 - 0.019 14.7 0.0 0.08 12.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 HAP1_N PF04849.8 EKE38418.1 - 0.011 14.7 1.9 0.011 14.7 1.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF812 PF05667.6 EKE38418.1 - 0.069 11.6 4.0 0.053 12.0 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.4 EKE38418.1 - 0.19 11.8 2.7 0.26 11.4 1.8 1.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAE1_CUT1_RppA PF08392.7 EKE38421.1 - 6.2e-84 281.5 0.0 7.8e-84 281.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EKE38421.1 - 1.9e-09 37.4 0.0 3.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.10 EKE38421.1 - 1.4e-07 31.5 0.0 4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EKE38421.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 EKE38421.1 - 0.0035 16.9 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Metallophos PF00149.23 EKE38422.1 - 2.2e-29 102.2 0.5 3.5e-29 101.6 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rad52_Rad22 PF04098.10 EKE38424.1 - 1.8e-33 115.4 0.2 2.2e-33 115.1 0.2 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3400 PF11880.3 EKE38424.1 - 0.052 12.7 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) YL1 PF05764.8 EKE38425.1 - 0.00022 20.9 21.9 0.00026 20.6 15.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Pro-rich PF15240.1 EKE38425.1 - 0.0005 20.2 16.2 0.00053 20.1 11.2 1.2 1 0 0 1 1 1 1 Proline-rich 7kD_coat PF02495.12 EKE38425.1 - 0.091 12.2 0.3 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 7kD viral coat protein alpha-hel2 PF14456.1 EKE38425.1 - 0.22 10.2 1.7 0.26 10.0 1.2 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF2890 PF11081.3 EKE38425.1 - 1.8 8.5 19.9 2.4 8.1 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 EKE38425.1 - 4.6 5.1 15.2 5.7 4.8 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EKE38425.1 - 5.1 5.4 28.0 6.3 5.1 19.4 1.1 1 0 0 1 1 1 0 Daxx Family TLD PF07534.11 EKE38426.1 - 2.1e-07 31.0 0.0 4.7e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 TLD ISG65-75 PF11727.3 EKE38426.1 - 0.074 12.1 0.6 0.097 11.7 0.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3583 PF12126.3 EKE38426.1 - 0.11 11.5 1.2 0.16 10.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Syntaxin-6_N PF09177.6 EKE38426.1 - 0.11 12.9 2.5 0.13 12.6 0.9 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4600 PF15372.1 EKE38426.1 - 0.13 12.5 5.2 0.23 11.6 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Mnd1 PF03962.10 EKE38426.1 - 0.15 11.7 6.1 0.23 11.1 4.2 1.2 1 0 0 1 1 1 0 Mnd1 family DUF4615 PF15393.1 EKE38426.1 - 0.17 12.1 2.3 0.45 10.7 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Flu_NS2 PF00601.14 EKE38426.1 - 0.18 12.0 2.3 0.3 11.3 1.6 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Fib_alpha PF08702.5 EKE38426.1 - 0.21 11.7 2.5 0.33 11.0 1.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 EKE38426.1 - 0.24 10.9 7.4 0.47 9.9 5.1 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 3-PAP PF12578.3 EKE38427.1 - 0.025 14.4 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 Myotubularin-associated protein MitMem_reg PF13012.1 EKE38427.1 - 0.067 13.2 2.6 0.42 10.7 1.8 2.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function UBN2_2 PF14227.1 EKE38427.1 - 0.25 10.8 3.2 2.1 7.9 0.5 2.5 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type JAB PF01398.16 EKE38428.1 - 3.1e-05 23.6 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Astro_capsid_p PF12226.3 EKE38428.1 - 0.078 12.2 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Clathrin_H_link PF13838.1 EKE38430.1 - 0.013 15.3 0.5 0.11 12.3 0.3 1.9 1 1 0 1 1 1 0 Clathrin-H-link SgrR_N PF12793.2 EKE38430.1 - 0.022 14.7 0.2 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term PolyA_pol_RNAbd PF12627.2 EKE38430.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A cwf21 PF08312.7 EKE38430.1 - 0.2 11.5 1.3 0.33 10.8 0.9 1.4 1 0 0 1 1 1 0 cwf21 domain Peptidase_M3 PF01432.15 EKE38431.1 - 1.2e-121 406.9 8.1 1.2e-121 406.9 5.6 1.6 2 0 0 2 2 2 1 Peptidase family M3 ATP-synt_8 PF00895.15 EKE38432.1 - 0.058 13.6 1.3 0.12 12.6 0.9 1.5 1 0 0 1 1 1 0 ATP synthase protein 8 Ras PF00071.17 EKE38433.1 - 3e-43 147.0 0.7 3.8e-43 146.6 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38433.1 - 1.6e-16 60.8 1.2 2.8e-16 60.0 0.1 1.9 2 1 1 3 3 3 1 Miro-like protein Arf PF00025.16 EKE38433.1 - 2.8e-15 55.9 0.4 3.7e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE38433.1 - 1.5e-07 31.0 0.9 3e-06 26.8 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE38433.1 - 3.7e-07 29.5 0.4 8.3e-07 28.3 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE38433.1 - 1.8e-05 24.0 0.1 2.5e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE38433.1 - 3.7e-05 23.6 1.4 0.00011 22.0 0.2 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EKE38433.1 - 0.00017 21.6 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain PduV-EutP PF10662.4 EKE38433.1 - 0.0046 16.4 1.6 0.012 15.0 0.1 2.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 EKE38433.1 - 0.0063 15.7 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Centromere protein M (CENP-M) AIG1 PF04548.11 EKE38433.1 - 0.0063 15.6 0.2 0.0063 15.6 0.1 2.3 2 1 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 EKE38433.1 - 0.0085 16.2 0.4 0.12 12.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EKE38433.1 - 0.018 15.3 1.8 0.12 12.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain Microcephalin PF12258.3 EKE38433.1 - 0.029 13.3 0.4 0.037 13.0 0.3 1.1 1 0 0 1 1 1 0 Microcephalin protein Septin PF00735.13 EKE38433.1 - 0.038 12.9 0.1 0.038 12.9 0.1 1.9 2 1 0 2 2 2 0 Septin UPF0079 PF02367.12 EKE38433.1 - 0.048 13.2 0.1 0.43 10.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF678 PF05077.7 EKE38433.1 - 0.053 13.5 0.7 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF678) MobB PF03205.9 EKE38433.1 - 0.083 12.5 1.1 0.19 11.4 0.3 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3173 PF11372.3 EKE38433.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Dzip-like_N PF13815.1 EKE38433.1 - 0.19 11.5 2.0 0.29 10.9 1.4 1.2 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal ubiquitin PF00240.18 EKE38434.1 - 1.2e-09 37.4 2.4 0.00085 18.6 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EKE38434.1 - 1.8e-08 33.9 3.5 2.4e-05 23.9 0.4 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Binary_toxB PF03495.9 EKE38434.1 - 0.01 14.5 1.3 0.015 13.9 0.9 1.2 1 0 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA E1-E2_ATPase PF00122.15 EKE38435.1 - 7.5e-60 201.8 0.1 2.4e-59 200.1 0.1 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKE38435.1 - 1.3e-39 135.5 5.0 1.3e-39 135.5 3.4 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKE38435.1 - 6.9e-28 98.5 0.0 2.1e-27 96.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE38435.1 - 9.5e-16 58.5 0.0 1.9e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE38435.1 - 1.2e-12 47.6 0.0 3.3e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EKE38435.1 - 9.1e-11 41.0 0.1 1.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EKE38435.1 - 5e-06 26.2 0.3 5e-06 26.2 0.2 4.0 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase PP2C PF00481.16 EKE38437.1 - 4.1e-54 183.6 0.0 5.7e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE38437.1 - 2.4e-07 30.3 0.0 4.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C adh_short PF00106.20 EKE38438.1 - 1.2e-31 109.9 0.0 1.5e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKE38438.1 - 2.2e-30 106.2 0.0 8.5e-30 104.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKE38438.1 - 5.5e-13 48.9 0.0 7.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKE38438.1 - 3.3e-05 23.4 0.9 7.9e-05 22.1 0.3 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKE38438.1 - 0.00024 21.1 0.0 0.00059 19.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EKE38438.1 - 0.00055 18.9 0.1 0.00087 18.2 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EKE38438.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain PCMT PF01135.14 EKE38438.1 - 0.05 13.1 0.1 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_M20 PF01546.23 EKE38439.1 - 7.3e-10 38.6 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EKE38439.1 - 0.00029 19.7 0.0 0.00055 18.8 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DUF1682 PF07946.9 EKE38440.1 - 4.3e-33 114.5 13.5 5.9e-33 114.0 9.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ssu72 PF04722.8 EKE38441.1 - 0.92 8.7 6.6 1.5 8.1 2.8 2.1 1 1 1 2 2 2 0 Ssu72-like protein Rsa3 PF14615.1 EKE38442.1 - 0.0052 16.0 0.2 0.02 14.1 0.2 2.0 1 0 0 1 1 1 1 Ribosome-assembly protein 3 tRNA-synt_1 PF00133.17 EKE38443.1 - 8.5e-48 162.7 0.6 1.1e-32 112.8 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EKE38443.1 - 1.4e-24 86.5 0.1 6.6e-11 41.4 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EKE38443.1 - 1.8e-11 43.9 0.3 5.3e-11 42.4 0.2 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EKE38443.1 - 1.8e-06 27.2 0.0 7.4e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain RNA_pol PF00940.14 EKE38443.1 - 0.043 12.2 0.1 0.24 9.8 0.0 2.1 2 0 0 2 2 2 0 DNA-dependent RNA polymerase PRKCSH_1 PF13015.1 EKE38444.1 - 0.00013 21.5 0.9 0.00019 20.9 0.6 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 EKE38444.1 - 2.4 7.3 8.5 79 2.3 5.8 2.2 1 1 0 1 1 1 0 Autophagy-related protein 27 CcmE PF03100.10 EKE38445.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 CcmE DUF1664 PF07889.7 EKE38445.1 - 0.1 12.3 1.5 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cation_efflux PF01545.16 EKE38446.1 - 4.8e-78 262.1 9.7 6.1e-78 261.7 6.7 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EKE38446.1 - 0.00051 19.1 16.4 0.00097 18.2 11.3 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Peptidase_U57 PF05582.7 EKE38446.1 - 2 7.3 7.3 33 3.3 5.1 2.2 1 1 0 1 1 1 0 YabG peptidase U57 DUF3816 PF12822.2 EKE38446.1 - 5.7 6.8 13.8 8.5 6.2 8.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) MCM PF00493.18 EKE38447.1 - 2e-134 447.5 1.2 2.7e-134 447.1 0.8 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKE38447.1 - 2.8e-16 60.0 0.4 8.6e-16 58.5 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKE38447.1 - 5.1e-06 25.7 0.1 0.00099 18.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKE38447.1 - 7.4e-05 22.4 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKE38447.1 - 0.0038 16.8 0.1 0.031 13.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EKE38447.1 - 0.0044 17.3 0.6 0.17 12.2 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Metallophos PF00149.23 EKE38448.1 - 1.8e-28 99.3 0.1 3.4e-28 98.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF755 PF05501.6 EKE38448.1 - 0.056 13.5 2.0 0.099 12.7 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PPP5 PF08321.7 EKE38448.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region Sld5 PF05916.6 EKE38449.1 - 0.00019 21.6 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein COX5A PF02284.11 EKE38449.1 - 0.17 11.8 0.7 0.45 10.4 0.5 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase subunit Va Med4 PF10018.4 EKE38449.1 - 0.2 11.0 1.7 0.24 10.7 0.3 1.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 C2 PF00168.25 EKE38450.1 - 1.4e-16 60.0 0.3 1.4e-16 60.0 0.2 2.3 2 0 0 2 2 2 1 C2 domain TLD PF07534.11 EKE38450.1 - 8.5e-05 22.5 0.1 0.0003 20.8 0.0 1.8 1 1 1 2 2 2 1 TLD NIF PF03031.13 EKE38454.1 - 1.2e-33 116.0 0.9 1.6e-33 115.6 0.6 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EKE38454.1 - 0.0013 19.0 0.5 0.22 11.7 0.0 2.2 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE38454.1 - 0.029 14.5 0.4 0.58 10.2 0.3 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Yippee-Mis18 PF03226.9 EKE38454.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PNK3P PF08645.6 EKE38454.1 - 0.055 12.9 0.7 0.26 10.7 0.1 2.2 1 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Peptidase_C97 PF05903.9 EKE38454.1 - 0.32 10.7 3.2 0.66 9.7 0.6 2.2 2 1 1 3 3 3 0 PPPDE putative peptidase domain RabGAP-TBC PF00566.13 EKE38455.1 - 7.4e-32 110.5 11.7 1.5e-31 109.5 8.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 EKE38456.1 - 3.2e-23 80.7 9.9 9.8e-08 31.6 0.1 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EKE38456.1 - 7.9e-14 51.3 0.0 2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex IncA PF04156.9 EKE38456.1 - 8.1 5.9 5.5 13 5.3 3.8 1.2 1 0 0 1 1 1 0 IncA protein Ras PF00071.17 EKE38457.1 - 5.2e-53 178.7 0.4 6e-53 178.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38457.1 - 3.4e-15 56.5 0.0 5.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38457.1 - 7.9e-14 51.2 0.1 9.1e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE38457.1 - 6.1e-07 28.8 0.0 7.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Endonuc-MspI PF09208.5 EKE38457.1 - 4.4e-06 25.9 0.0 6.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease MspI GTP_EFTU PF00009.22 EKE38457.1 - 2.7e-05 23.6 0.6 0.00011 21.6 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RE_ApaLI PF09499.5 EKE38457.1 - 0.042 13.2 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Proteasome PF00227.21 EKE38458.1 - 1.1e-58 197.7 0.0 5.1e-58 195.4 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EKE38458.1 - 2.8e-11 42.5 0.3 3.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PQ-loop PF04193.9 EKE38459.1 - 7.8e-16 57.3 14.3 1.4e-10 40.5 2.2 3.4 4 0 0 4 4 4 2 PQ loop repeat Transposase_22 PF02994.9 EKE38460.1 - 0.019 13.5 3.0 0.02 13.3 2.1 1.1 1 0 0 1 1 1 0 L1 transposable element DUF4252 PF14060.1 EKE38460.1 - 0.6 9.6 4.2 0.45 10.0 1.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) Snapin_Pallidin PF14712.1 EKE38460.1 - 0.73 10.1 4.8 0.63 10.3 1.8 1.9 1 1 1 2 2 2 0 Snapin/Pallidin ASFV_J13L PF05568.6 EKE38461.1 - 0.12 11.8 0.6 0.17 11.4 0.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein C1_3 PF07649.7 EKE38462.1 - 0.0065 16.4 11.2 0.024 14.6 7.8 2.1 1 0 0 1 1 1 1 C1-like domain C1_1 PF00130.17 EKE38462.1 - 0.17 11.6 19.0 0.073 12.8 10.5 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 EKE38462.1 - 0.32 11.1 9.6 1.3 9.1 6.7 2.2 1 0 0 1 1 1 0 C1 domain HECT PF00632.20 EKE38463.1 - 1.1e-91 307.3 1.6 1.8e-91 306.6 1.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Atg14 PF10186.4 EKE38464.1 - 9.8e-06 24.7 11.4 9.8e-06 24.7 7.9 2.0 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Myosin_tail_1 PF01576.14 EKE38464.1 - 0.0018 16.1 2.0 0.0018 16.1 1.4 2.3 1 1 1 2 2 2 2 Myosin tail ThiF PF00899.16 EKE38464.1 - 0.055 13.2 2.1 0.058 13.2 0.2 1.9 1 1 1 2 2 2 0 ThiF family SecD-TM1 PF13721.1 EKE38464.1 - 1.1 9.5 5.0 0.7 10.1 0.2 2.5 1 1 1 2 2 2 0 SecD export protein N-terminal TM region MutS_III PF05192.13 EKE38464.1 - 1.2 8.8 4.7 1.7 8.3 3.3 1.3 1 0 0 1 1 1 0 MutS domain III DUF724 PF05266.9 EKE38464.1 - 2.3 7.7 23.7 0.92 9.0 10.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Tox-REase-2 PF15646.1 EKE38464.1 - 7.1 6.5 9.4 1.1 9.0 0.6 2.5 1 1 2 3 3 3 0 Restriction endonuclease fold toxin 2 Mto2_bdg PF12808.2 EKE38464.1 - 8.2 6.6 12.5 6.7 6.8 2.8 3.4 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PIG-L PF02585.12 EKE38465.1 - 1.4e-27 96.6 0.0 4e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.15 EKE38465.1 - 9.5e-20 71.1 0.0 1.7e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PHD PF00628.24 EKE38466.1 - 0.052 13.2 1.7 0.052 13.2 1.2 2.1 2 0 0 2 2 2 0 PHD-finger DUF3586 PF12131.3 EKE38466.1 - 0.47 10.5 7.1 0.23 11.5 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3586) Toxin_16 PF07945.6 EKE38466.1 - 0.73 9.5 5.3 0.95 9.1 0.2 3.2 3 0 0 3 3 3 0 Janus-atracotoxin DnaJ_CXXCXGXG PF00684.14 EKE38466.1 - 4.5 7.4 10.5 1.7 8.7 3.6 2.6 1 1 1 2 2 2 0 DnaJ central domain Sybindin PF04099.7 EKE38467.1 - 3.5e-18 65.6 1.6 4e-18 65.4 1.1 1.0 1 0 0 1 1 1 1 Sybindin-like family ABC_tran PF00005.22 EKE38468.1 - 5.3e-27 94.7 0.0 1.1e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EKE38468.1 - 2.3e-15 56.5 21.5 6.2e-15 55.0 14.9 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EKE38468.1 - 3.6e-14 53.4 2.7 3.9e-11 43.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EKE38468.1 - 3e-05 23.2 0.1 0.0074 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EKE38468.1 - 0.01 15.0 0.0 0.095 11.9 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKE38468.1 - 0.13 11.8 0.2 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EKE38468.1 - 0.21 11.5 0.0 0.77 9.7 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EKE38468.1 - 9.8 6.4 10.0 0.36 11.1 0.6 2.4 3 0 0 3 3 3 0 AAA domain Ribosomal_L7Ae PF01248.21 EKE38470.1 - 1.2e-27 95.2 0.3 1.5e-27 94.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EKE38470.1 - 6.6e-05 22.7 0.0 8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EKE38470.1 - 0.0017 18.1 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain PqqD PF05402.7 EKE38470.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) TFIIS_C PF01096.13 EKE38471.1 - 2.9e-21 74.8 13.4 9e-21 73.2 1.6 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EKE38471.1 - 1.1e-06 28.3 4.6 0.00017 21.3 0.2 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EKE38471.1 - 1.2e-06 28.0 2.7 1.2e-06 28.0 1.8 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.1 EKE38471.1 - 0.0012 19.0 4.9 0.0079 16.4 0.1 2.3 2 1 0 2 2 2 1 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 EKE38471.1 - 0.0014 18.0 8.0 0.08 12.4 0.0 3.4 3 1 0 3 3 3 1 DNA directed RNA polymerase, 7 kDa subunit DUF2296 PF10058.4 EKE38471.1 - 0.0024 17.5 10.1 0.0053 16.4 0.2 3.2 2 2 1 3 3 3 1 Predicted integral membrane metal-binding protein (DUF2296) Terminase_GpA PF05876.7 EKE38471.1 - 0.0098 14.2 0.7 0.012 13.9 0.5 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) zf-GRF PF06839.7 EKE38471.1 - 0.018 14.9 1.1 0.018 14.9 0.8 2.9 2 1 0 2 2 2 0 GRF zinc finger Baculo_LEF5_C PF11792.3 EKE38471.1 - 0.029 13.7 0.3 0.029 13.7 0.2 2.2 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain IBR PF01485.16 EKE38471.1 - 0.039 13.8 9.5 0.18 11.7 0.3 3.1 1 1 2 3 3 3 0 IBR domain FTH PF01827.22 EKE38471.1 - 0.047 13.2 0.8 0.091 12.3 0.5 1.5 1 1 0 1 1 1 0 FTH domain zf-DNA_Pol PF08996.5 EKE38471.1 - 0.059 12.7 7.0 0.27 10.5 3.3 2.2 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger Mu-like_Com PF10122.4 EKE38471.1 - 0.073 12.1 0.6 0.43 9.6 0.1 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com DZR PF12773.2 EKE38471.1 - 0.11 12.3 7.7 2.7 7.8 3.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EKE38471.1 - 0.15 11.4 9.5 0.67 9.3 0.0 3.6 4 1 0 4 4 4 0 TFIIB zinc-binding zf-trcl PF13451.1 EKE38471.1 - 0.17 11.5 5.2 8.7 6.0 0.1 3.4 3 0 0 3 3 3 0 Probable zinc-binding domain Ogr_Delta PF04606.7 EKE38471.1 - 0.22 11.1 15.3 4.5 6.9 3.2 3.8 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.1 EKE38471.1 - 0.22 10.7 10.3 0.92 8.8 2.0 3.2 3 1 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EKE38471.1 - 0.23 11.1 7.0 1.9 8.2 0.9 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L37e PF01907.14 EKE38471.1 - 0.23 11.2 0.1 0.23 11.2 0.0 3.1 4 0 0 4 4 3 0 Ribosomal protein L37e Ribosomal_L37ae PF01780.14 EKE38471.1 - 0.79 9.6 4.2 1.3 8.9 0.1 2.4 1 1 1 2 2 2 0 Ribosomal L37ae protein family HypA PF01155.14 EKE38471.1 - 0.9 9.2 5.0 6 6.6 0.4 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C3HC PF07967.8 EKE38471.1 - 0.99 9.1 5.3 1.6 8.4 0.2 2.5 1 1 1 2 2 2 0 C3HC zinc finger-like Tnp_zf-ribbon_2 PF13842.1 EKE38471.1 - 1 9.8 0.1 1 9.8 0.1 3.8 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Zn-ribbon_8 PF09723.5 EKE38471.1 - 1 9.3 10.8 7 6.7 0.0 4.0 4 0 0 4 4 4 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 EKE38471.1 - 1.2 8.9 9.3 2 8.2 1.9 3.6 3 1 1 4 4 4 0 PhnA Zinc-Ribbon zf-C2HC5 PF06221.8 EKE38471.1 - 1.2 8.9 6.1 0.42 10.4 0.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type CpXC PF14353.1 EKE38471.1 - 1.6 8.7 8.7 0.71 9.8 0.2 2.7 1 1 2 3 3 3 0 CpXC protein Nudix_N_2 PF14803.1 EKE38471.1 - 1.8 8.3 5.9 6.3 6.5 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal Yippee-Mis18 PF03226.9 EKE38471.1 - 1.9 8.6 5.3 7.7 6.6 0.8 2.8 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-B_box PF00643.19 EKE38471.1 - 2.2 8.2 7.2 10 6.0 0.1 3.1 3 0 0 3 3 3 0 B-box zinc finger C1_1 PF00130.17 EKE38471.1 - 2.7 7.7 9.3 0.32 10.7 0.5 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rpr2 PF04032.11 EKE38471.1 - 2.7 7.9 6.6 3.9 7.4 4.0 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_5 PF14634.1 EKE38471.1 - 3.1 7.5 7.8 4.9 6.9 0.4 2.5 2 1 0 2 2 2 0 zinc-RING finger domain zf-CHY PF05495.7 EKE38471.1 - 4.8 7.4 9.3 18 5.6 3.9 2.5 1 1 1 2 2 2 0 CHY zinc finger NOB1_Zn_bind PF08772.6 EKE38471.1 - 5.1 6.9 9.9 4.1 7.3 0.1 2.8 1 1 2 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_S27e PF01667.12 EKE38471.1 - 5.3 6.6 8.1 11 5.7 0.6 3.1 2 2 1 3 3 3 0 Ribosomal protein S27 zinc_ribbon_2 PF13240.1 EKE38471.1 - 5.8 6.5 14.1 5.3 6.6 2.2 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Arrestin_N PF00339.24 EKE38472.1 - 0.0016 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HIM1 PF08732.5 EKE38472.1 - 0.0069 14.8 0.3 0.013 13.9 0.0 1.6 2 0 0 2 2 2 1 HIM1 Arrestin_C PF02752.17 EKE38472.1 - 0.013 15.6 0.2 2.3 8.3 0.2 2.1 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 EKE38472.1 - 0.048 12.9 0.4 0.21 10.9 0.3 1.8 2 0 0 2 2 2 0 SpoOM protein Sec7 PF01369.15 EKE38474.1 - 2.4e-07 30.6 0.1 1.1e-06 28.4 0.1 2.2 1 0 0 1 1 1 1 Sec7 domain IMS PF00817.15 EKE38475.1 - 5e-38 130.2 0.0 1e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EKE38475.1 - 1.4e-13 50.8 0.0 3.3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EKE38475.1 - 1.3e-09 38.0 0.1 6.8e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EKE38475.1 - 6.6e-05 22.7 0.1 0.0033 17.3 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif DUF1805 PF08827.6 EKE38475.1 - 0.0086 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1805) DUF4414 PF14377.1 EKE38475.1 - 0.074 12.9 0.2 0.074 12.9 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4414) PTCB-BRCT PF12738.2 EKE38475.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Pkinase PF00069.20 EKE38476.1 - 7.7e-50 169.4 6.2 9.8e-50 169.1 4.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38476.1 - 1.9e-34 118.9 0.7 2.7e-34 118.4 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE38476.1 - 2.4e-06 26.7 0.0 1.3e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like DUF2779 PF11074.3 EKE38476.1 - 2.2 8.3 10.6 0.56 10.2 3.2 2.8 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) Helicase_C PF00271.26 EKE38477.1 - 5.6e-12 45.3 0.1 2e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 EKE38477.1 - 8e-10 38.6 0.1 8e-10 38.6 0.1 2.9 3 1 0 3 3 3 1 Helicase associated domain (HA2) AAA_22 PF13401.1 EKE38477.1 - 0.00087 19.4 0.1 0.0041 17.2 0.1 2.2 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EKE38477.1 - 0.0022 16.9 0.0 0.0052 15.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein OB_NTP_bind PF07717.11 EKE38477.1 - 0.0026 17.5 4.6 0.0032 17.2 0.2 3.3 4 0 0 4 4 4 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 EKE38477.1 - 0.052 13.0 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Apyrase PF06079.6 EKE38478.1 - 6.1e-86 288.1 4.4 7.5e-86 287.8 3.1 1.0 1 0 0 1 1 1 1 Apyrase Rsd_AlgQ PF04353.8 EKE38479.1 - 0.043 13.5 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ RhoGEF PF00621.15 EKE38480.1 - 1.8e-35 122.4 1.0 3.8e-35 121.4 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EKE38481.1 - 0.14 12.3 2.6 0.25 11.5 1.0 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain RhoGAP PF00620.22 EKE38482.1 - 2.1e-24 85.8 2.4 2.1e-24 85.8 1.6 2.9 4 0 0 4 4 4 1 RhoGAP domain DUF1637 PF07847.7 EKE38482.1 - 0.0091 15.3 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Beta_elim_lyase PF01212.16 EKE38483.1 - 2.5e-69 233.6 0.0 3.2e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EKE38483.1 - 0.0046 15.4 0.0 0.0069 14.8 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ras PF00071.17 EKE38485.1 - 6e-51 172.0 3.8 7.2e-51 171.7 2.6 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE38485.1 - 7e-18 64.4 1.1 8.1e-18 64.2 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE38485.1 - 1.7e-17 64.0 1.1 2.9e-17 63.2 0.7 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKE38485.1 - 1.6e-09 37.7 0.7 2.5e-09 37.1 0.4 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE38485.1 - 1.3e-08 34.5 1.1 1e-07 31.6 0.8 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE38485.1 - 2.6e-08 33.2 0.5 3.6e-08 32.8 0.3 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE38485.1 - 4.8e-07 29.1 0.7 5.8e-07 28.8 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EKE38485.1 - 4.3e-05 22.7 1.5 5.3e-05 22.4 1.1 1.0 1 0 0 1 1 1 1 AAA ATPase domain Septin PF00735.13 EKE38485.1 - 0.00031 19.8 0.4 0.00045 19.3 0.1 1.4 1 1 0 1 1 1 1 Septin PduV-EutP PF10662.4 EKE38485.1 - 0.001 18.5 0.3 0.0081 15.6 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE38485.1 - 0.0016 17.6 2.2 0.0018 17.4 0.4 1.9 2 1 1 3 3 3 1 Protein of unknown function, DUF258 SdrG_C_C PF10425.4 EKE38485.1 - 0.0029 17.6 6.2 0.004 17.1 4.3 1.1 1 0 0 1 1 1 1 C-terminus of bacterial fibrinogen-binding adhesin G-alpha PF00503.15 EKE38485.1 - 0.0042 15.8 0.8 0.0042 15.8 0.6 2.5 1 1 2 3 3 3 1 G-protein alpha subunit FeoB_N PF02421.13 EKE38485.1 - 0.0059 15.8 0.3 0.017 14.4 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EKE38485.1 - 0.007 15.9 1.5 0.019 14.5 0.3 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_21 PF13304.1 EKE38485.1 - 0.012 15.6 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EKE38485.1 - 0.028 14.1 2.5 0.4 10.3 1.8 2.1 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EKE38485.1 - 0.034 13.8 0.6 0.097 12.3 0.4 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EKE38485.1 - 0.04 13.4 3.2 0.17 11.4 1.3 2.1 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EKE38485.1 - 0.061 13.6 0.6 0.11 12.8 0.4 1.5 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 EKE38485.1 - 0.076 12.8 1.5 2.4 7.9 0.2 2.3 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EKE38485.1 - 0.11 12.7 0.3 0.25 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EKE38486.1 - 6.9e-54 182.7 0.1 8.5e-54 182.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38486.1 - 6e-21 74.6 0.0 8.7e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE38486.1 - 5e-05 23.1 0.0 0.00022 21.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EKE38486.1 - 0.0036 16.3 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EKE38486.1 - 0.025 14.1 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EKE38486.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kin17_mid PF10357.4 EKE38487.1 - 1.6e-37 127.9 2.8 1.6e-37 127.9 1.9 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein TFIID_90kDa PF04494.10 EKE38487.1 - 0.02 14.9 1.9 0.039 14.0 0.5 1.9 1 1 0 2 2 2 0 WD40 associated region in TFIID subunit VD10_N PF08476.5 EKE38487.1 - 0.034 13.6 0.2 0.1 12.0 0.1 1.8 1 0 0 1 1 1 0 Viral D10 N-terminal zf-C2H2_2 PF12756.2 EKE38487.1 - 0.042 13.9 7.6 0.048 13.7 2.7 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF4021 PF13213.1 EKE38487.1 - 0.064 12.8 2.4 1.7 8.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4021) Cdc6_C PF09079.6 EKE38487.1 - 0.068 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal DSL PF01414.14 EKE38487.1 - 0.1 12.5 5.8 0.18 11.8 4.0 1.3 1 0 0 1 1 1 0 Delta serrate ligand zf-met PF12874.2 EKE38487.1 - 0.1 12.8 6.8 0.28 11.4 4.7 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EKE38487.1 - 4.8 7.4 14.9 0.24 11.6 6.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BDV_P24 PF06595.6 EKE38488.1 - 0.56 9.9 5.9 0.44 10.2 2.5 1.9 1 1 1 2 2 2 0 Borna disease virus P24 protein Myb_DNA-binding PF00249.26 EKE38489.1 - 4.6e-09 36.1 0.1 8e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain RabGAP-TBC PF00566.13 EKE38490.1 - 1.7e-16 60.3 1.3 3.3e-16 59.3 0.9 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1041 PF06292.12 EKE38490.1 - 0.022 14.9 0.1 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Ribosomal_S9 PF00380.14 EKE38491.1 - 6.3e-38 129.7 0.1 8e-38 129.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF217 PF02697.9 EKE38492.1 - 0.00036 20.7 1.1 0.00083 19.5 0.7 1.6 1 0 0 1 1 1 1 Uncharacterized ACR, COG1753 DUF3449 PF11931.3 EKE38493.1 - 2.7e-54 183.6 2.8 2.7e-54 183.6 1.9 3.0 2 1 2 4 4 4 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 EKE38493.1 - 4.7e-08 32.9 17.1 5.3e-07 29.5 3.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKE38493.1 - 2.9e-07 30.4 7.9 0.00019 21.5 1.9 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EKE38493.1 - 3.8e-07 30.1 12.8 8e-06 25.9 3.5 3.0 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EKE38493.1 - 0.11 12.2 16.5 0.059 13.1 4.1 2.9 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 EKE38493.1 - 0.22 11.9 7.8 1.8 9.0 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EKE38493.1 - 0.8 10.1 11.5 2.9 8.4 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-U1 PF06220.7 EKE38493.1 - 1.5 8.4 8.9 0.57 9.7 2.9 2.4 2 0 0 2 2 2 0 U1 zinc finger zf-DBF PF07535.7 EKE38493.1 - 3.7 7.3 11.7 1.4 8.6 2.8 2.6 2 0 0 2 2 2 0 DBF zinc finger EMP24_GP25L PF01105.19 EKE38494.1 - 4.8e-36 124.2 1.4 5.4e-36 124.0 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PCI_Csn8 PF10075.4 EKE38494.1 - 0.0055 16.4 0.2 0.023 14.4 0.1 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF1461 PF07314.6 EKE38494.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Oxysterol_BP PF01237.13 EKE38494.1 - 0.028 12.9 0.1 0.036 12.5 0.1 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Ribosomal_L5_C PF00673.16 EKE38495.1 - 3.3e-23 81.2 0.0 4.7e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EKE38495.1 - 9.3e-19 66.9 0.0 2.5e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 RNA_pol_Rpb8 PF03870.10 EKE38496.1 - 2.1e-29 102.4 0.6 2.4e-29 102.2 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 TLD PF07534.11 EKE38497.1 - 0.047 13.6 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 TLD Slx4 PF09494.5 EKE38498.1 - 2e-11 43.4 0.2 5.9e-11 41.9 0.1 1.9 1 0 0 1 1 1 1 Slx4 endonuclease NAD_binding_6 PF08030.7 EKE38498.1 - 0.33 10.8 4.6 0.075 12.9 0.5 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF2039 PF10217.4 EKE38499.1 - 4.8e-25 87.4 17.5 1.2e-24 86.0 12.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) BUD22 PF09073.5 EKE38499.1 - 0.015 14.4 12.9 0.016 14.3 9.0 1.1 1 0 0 1 1 1 0 BUD22 ADK_lid PF05191.9 EKE38499.1 - 0.017 14.7 8.8 1.1 8.9 0.1 3.6 3 1 0 3 3 3 0 Adenylate kinase, active site lid Cript PF10235.4 EKE38499.1 - 0.039 14.2 9.4 0.039 14.2 6.5 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Cytochrome_C7 PF14522.1 EKE38499.1 - 0.3 10.7 9.9 2.3 7.9 6.1 2.7 1 1 1 2 2 2 0 Cytochrome c7 Tnp_zf-ribbon_2 PF13842.1 EKE38499.1 - 7.2 7.1 15.3 11 6.5 7.5 2.9 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DHH PF01368.15 EKE38500.1 - 1.3e-07 31.3 0.6 3.4e-07 30.0 0.4 1.7 1 1 0 1 1 1 1 DHH family DHHA1 PF02272.14 EKE38500.1 - 5.2e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 DHHA1 domain Vps39_1 PF10366.4 EKE38500.1 - 0.0036 17.3 0.8 2.3 8.2 0.0 2.7 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 START PF01852.14 EKE38501.1 - 1.5e-22 79.9 0.0 1.8e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 START domain DUF4327 PF14217.1 EKE38501.1 - 0.19 11.5 1.8 2.7 7.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4327) DUF4359 PF14271.1 EKE38502.1 - 0.013 15.8 0.3 0.13 12.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) bZIP_Maf PF03131.12 EKE38503.1 - 2.9e-09 37.1 7.9 4e-09 36.6 5.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EKE38503.1 - 5.8e-08 32.5 16.4 8.7e-08 32.0 11.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKE38503.1 - 1.3e-06 28.1 13.1 2.4e-06 27.2 9.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PEPcase PF00311.12 EKE38503.1 - 0.0056 14.6 2.3 0.0061 14.4 1.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase DUF4618 PF15397.1 EKE38503.1 - 0.028 13.7 7.6 0.034 13.4 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TFR_dimer PF04253.10 EKE38503.1 - 0.036 13.6 0.4 0.063 12.8 0.3 1.4 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain AAA_27 PF13514.1 EKE38503.1 - 0.067 10.8 5.9 0.08 10.6 4.1 1.0 1 0 0 1 1 1 0 AAA domain Cob_adeno_trans PF01923.13 EKE38503.1 - 0.1 12.3 1.2 0.13 12.0 0.9 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TBPIP PF07106.8 EKE38503.1 - 0.1 12.1 12.7 0.13 11.7 4.7 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EKE38503.1 - 0.42 8.9 8.6 0.52 8.6 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TSC22 PF01166.13 EKE38503.1 - 0.75 9.8 9.1 0.2 11.6 4.0 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.10 EKE38503.1 - 1 8.4 7.5 1.3 8.1 5.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF904 PF06005.7 EKE38503.1 - 1.1 9.5 10.4 0.71 10.2 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EKE38503.1 - 1.6 6.4 8.2 1.8 6.2 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EKE38503.1 - 8.4 5.9 8.2 2 7.9 3.4 1.7 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EKE38504.1 - 0.00067 19.4 15.3 0.0014 18.3 10.6 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 EKE38504.1 - 0.008 15.4 6.2 0.0087 15.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Bap31 PF05529.7 EKE38504.1 - 0.0085 15.5 9.7 0.0091 15.4 6.8 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_TATA_bd PF12325.3 EKE38504.1 - 0.012 15.3 12.9 0.013 15.2 9.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 EKE38504.1 - 0.019 14.7 10.8 0.019 14.7 7.5 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SF-assemblin PF06705.6 EKE38504.1 - 0.028 13.5 7.3 0.035 13.2 5.1 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin TPR_MLP1_2 PF07926.7 EKE38504.1 - 0.038 13.7 8.9 0.046 13.4 6.1 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Borrelia_lipo_1 PF05714.6 EKE38504.1 - 0.063 12.3 9.0 0.067 12.2 6.2 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein Med9 PF07544.8 EKE38504.1 - 0.068 12.9 13.7 0.33 10.7 1.9 2.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 APG6 PF04111.7 EKE38504.1 - 0.11 11.5 11.2 0.12 11.3 7.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EKE38504.1 - 0.11 12.8 9.5 0.15 12.4 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HalX PF08663.5 EKE38504.1 - 0.14 12.1 5.3 0.19 11.7 3.7 1.3 1 0 0 1 1 1 0 HalX domain Cast PF10174.4 EKE38504.1 - 0.15 10.0 12.9 0.16 9.9 9.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF4509 PF14970.1 EKE38504.1 - 0.16 11.6 2.7 0.16 11.6 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) HTH_26 PF13443.1 EKE38504.1 - 0.17 12.1 0.3 0.17 12.1 0.2 1.5 2 0 0 2 2 1 0 Cro/C1-type HTH DNA-binding domain Baculo_PEP_C PF04513.7 EKE38504.1 - 0.18 11.6 1.3 0.21 11.4 0.9 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NCD2 PF04905.8 EKE38504.1 - 0.19 11.5 3.2 0.22 11.2 2.2 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) DUF4511 PF14974.1 EKE38504.1 - 0.2 11.4 2.7 0.28 10.9 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4511) Lipoprotein_20 PF13942.1 EKE38504.1 - 0.22 11.0 6.2 0.27 10.7 4.3 1.3 1 0 0 1 1 1 0 YfhG lipoprotein PilO PF04350.8 EKE38504.1 - 0.29 11.0 7.2 0.34 10.8 5.0 1.2 1 0 0 1 1 1 0 Pilus assembly protein, PilO AATF-Che1 PF13339.1 EKE38504.1 - 0.29 11.2 6.3 0.67 10.1 4.4 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Med4 PF10018.4 EKE38504.1 - 0.33 10.3 10.1 0.43 9.9 7.0 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TMCO5 PF14992.1 EKE38504.1 - 0.39 9.8 11.3 0.4 9.7 7.9 1.0 1 0 0 1 1 1 0 TMCO5 family HemX PF04375.9 EKE38504.1 - 0.39 9.2 5.8 0.44 9.0 4.0 1.1 1 0 0 1 1 1 0 HemX Phage_GP20 PF06810.6 EKE38504.1 - 0.48 9.8 11.0 0.92 8.9 7.6 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 ADIP PF11559.3 EKE38504.1 - 0.49 10.2 10.8 0.94 9.3 7.5 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.6 EKE38504.1 - 0.53 9.6 6.7 0.74 9.1 4.6 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DIT1_PvcA PF05141.7 EKE38504.1 - 0.54 9.5 3.2 0.54 9.5 2.2 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein AAA_13 PF13166.1 EKE38504.1 - 0.56 8.5 9.0 0.61 8.4 6.2 1.0 1 0 0 1 1 1 0 AAA domain Ax_dynein_light PF10211.4 EKE38504.1 - 0.6 9.9 12.1 0.047 13.5 3.6 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain DUF2205 PF10224.4 EKE38504.1 - 0.6 9.7 9.7 0.06 12.9 3.1 1.7 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF1465 PF07323.7 EKE38504.1 - 0.68 9.4 4.5 0.68 9.4 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF4279 PF14106.1 EKE38504.1 - 0.85 9.5 5.5 0.66 9.8 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) DUF641 PF04859.7 EKE38504.1 - 0.9 9.2 7.1 1.2 8.8 4.9 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) COG5 PF10392.4 EKE38504.1 - 0.93 9.4 5.8 1 9.3 4.0 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Atg14 PF10186.4 EKE38504.1 - 1 8.2 10.4 1.2 8.0 7.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EKE38504.1 - 1.3 8.5 14.9 3.7 7.1 2.8 2.9 1 1 2 3 3 3 0 Septum formation initiator DUF4061 PF13270.1 EKE38504.1 - 1.3 9.1 6.2 1.7 8.8 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Ribosomal_L29 PF00831.18 EKE38504.1 - 1.3 8.7 13.2 0.92 9.2 0.4 2.5 1 1 1 2 2 2 0 Ribosomal L29 protein Fib_alpha PF08702.5 EKE38504.1 - 1.3 9.1 7.1 1.8 8.6 4.9 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MerR-DNA-bind PF09278.6 EKE38504.1 - 1.3 9.4 8.2 0.73 10.2 2.9 2.1 1 1 1 2 2 2 0 MerR, DNA binding SlyX PF04102.7 EKE38504.1 - 1.5 9.2 8.8 0.76 10.1 2.2 2.3 1 1 1 2 2 2 0 SlyX IncA PF04156.9 EKE38504.1 - 1.5 8.3 11.0 1.7 8.2 7.6 1.1 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EKE38504.1 - 1.7 7.5 7.1 1.8 7.4 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2956 PF11169.3 EKE38504.1 - 2 8.4 5.7 2.6 8.0 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2956) Prefoldin_2 PF01920.15 EKE38504.1 - 2.1 8.1 15.1 0.81 9.4 5.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit TMPIT PF07851.8 EKE38504.1 - 2.3 7.2 6.2 2.4 7.1 4.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.1 EKE38504.1 - 2.3 8.7 7.9 5.8 7.4 5.5 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PspB PF06667.7 EKE38504.1 - 2.6 8.0 4.6 4.6 7.2 3.2 1.7 1 1 0 1 1 1 0 Phage shock protein B GrpE PF01025.14 EKE38504.1 - 2.6 7.5 9.3 3.3 7.2 6.4 1.4 1 1 0 1 1 1 0 GrpE Prefoldin PF02996.12 EKE38504.1 - 2.9 7.5 12.0 1.7 8.3 3.2 2.6 1 1 2 3 3 3 0 Prefoldin subunit UPF0242 PF06785.6 EKE38504.1 - 3.3 6.2 9.4 3.4 6.2 6.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Pox_A_type_inc PF04508.7 EKE38504.1 - 3.4 7.6 14.0 12 5.9 1.0 3.7 3 1 1 4 4 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 EKE38504.1 - 3.7 7.5 8.4 1.6 8.7 1.2 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4559 PF15112.1 EKE38504.1 - 4.1 6.4 8.7 5 6.1 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tho2 PF11262.3 EKE38504.1 - 5.1 6.0 7.3 5.6 5.9 5.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TSC22 PF01166.13 EKE38504.1 - 5.2 7.1 9.0 5.3 7.0 0.4 2.8 1 1 2 3 3 3 0 TSC-22/dip/bun family AAA_23 PF13476.1 EKE38504.1 - 6.1 7.1 13.1 6.8 6.9 9.1 1.1 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EKE38504.1 - 6.6 5.0 11.4 6.8 4.9 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4337 PF14235.1 EKE38504.1 - 7.1 6.4 8.4 7.7 6.3 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Lge1 PF11488.3 EKE38504.1 - 7.5 6.8 7.6 27 5.0 5.3 2.0 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 V_ATPase_I PF01496.14 EKE38504.1 - 7.9 4.1 8.1 7.8 4.2 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.4 EKE38504.1 - 8.2 6.4 12.0 1.4e+02 2.4 8.3 2.5 1 1 0 1 1 1 0 Haemolysin XhlA Pkinase PF00069.20 EKE38505.1 - 4.4e-42 144.0 0.1 9e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38505.1 - 2.2e-21 76.0 0.0 3.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE38505.1 - 0.0029 16.5 0.1 0.14 11.1 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EKE38505.1 - 0.0084 15.8 0.0 0.062 13.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EKE38505.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CH PF00307.26 EKE38506.1 - 1.8e-08 34.4 0.1 2.2e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKE38506.1 - 0.011 15.4 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 0 CAMSAP CH domain RhoGEF PF00621.15 EKE38507.1 - 3.2e-37 128.1 3.2 5.7e-37 127.3 2.2 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF3941 PF13081.1 EKE38507.1 - 0.53 10.2 0.1 0.53 10.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3941) Adaptin_binding PF10199.4 EKE38508.1 - 0.0002 21.6 7.7 0.0075 16.5 5.4 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF2514 PF10721.4 EKE38508.1 - 0.1 12.2 1.6 0.16 11.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Pkinase_Tyr PF07714.12 EKE38509.1 - 7e-53 179.3 0.0 1.2e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38509.1 - 1.6e-50 171.7 0.1 2.8e-50 170.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain VSP PF03302.8 EKE38509.1 - 3.5 6.1 132.5 0.0084 14.7 19.7 4.9 1 1 2 4 4 4 0 Giardia variant-specific surface protein VPS9 PF02204.13 EKE38510.1 - 5.4e-14 52.0 0.5 1.8e-13 50.4 0.4 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF535 PF04393.8 EKE38511.1 - 0.064 12.1 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Adaptin_N PF01602.15 EKE38513.1 - 1e-44 152.8 21.8 1.2e-44 152.5 15.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EKE38513.1 - 1.7e-12 47.6 2.1 1.7e-12 47.6 1.5 3.0 3 0 0 3 3 3 1 Adaptin C-terminal domain ANT PF03374.9 EKE38513.1 - 0.091 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain GnsAB PF08178.6 EKE38514.1 - 0.017 14.7 0.1 0.073 12.7 0.1 2.1 1 0 0 1 1 1 0 GnsA/GnsB family USP8_interact PF08941.5 EKE38514.1 - 0.031 13.5 1.1 0.095 12.0 0.7 1.8 1 0 0 1 1 1 0 USP8 interacting IncA PF04156.9 EKE38515.1 - 4.8e-05 23.0 30.3 4.8e-05 23.0 21.0 6.0 1 1 3 4 4 4 1 IncA protein ERM PF00769.14 EKE38515.1 - 0.0059 16.1 28.5 0.0059 16.1 19.8 5.1 1 1 3 4 4 4 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EKE38515.1 - 0.0086 15.2 5.3 0.0086 15.2 3.7 4.4 1 1 4 5 5 5 3 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EKE38515.1 - 0.026 14.3 126.7 0.1 12.4 13.1 5.8 1 1 5 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CH PF00307.26 EKE38516.1 - 9.7e-14 51.3 0.2 1.2e-13 51.0 0.2 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Glycos_transf_2 PF00535.21 EKE38516.1 - 0.017 14.7 0.2 0.033 13.8 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 CAMSAP_CH PF11971.3 EKE38516.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Ufd2P_core PF10408.4 EKE38517.1 - 6.5e-79 265.8 41.3 6.5e-79 265.8 28.6 1.9 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 EKE38517.1 - 4.2e-21 74.6 1.5 6.9e-21 74.0 0.4 1.9 2 0 0 2 2 2 1 U-box domain eIF_4EBP PF05456.6 EKE38517.1 - 0.44 10.2 2.2 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RasGEF PF00617.14 EKE38518.1 - 6.8e-13 48.7 4.1 6.8e-13 48.7 2.8 2.6 2 1 1 3 3 3 1 RasGEF domain Ndr PF03096.9 EKE38518.1 - 0.021 13.2 0.0 0.044 12.2 0.0 1.4 1 0 0 1 1 1 0 Ndr family MreD PF04093.7 EKE38519.1 - 0.034 14.0 8.5 0.057 13.2 5.9 1.4 1 1 0 1 1 1 0 rod shape-determining protein MreD Peptidase_S9 PF00326.16 EKE38520.1 - 2.4e-23 82.4 0.0 4.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.7 EKE38520.1 - 5.4e-06 25.9 1.0 0.028 14.1 0.2 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Abhydrolase_5 PF12695.2 EKE38520.1 - 0.00025 20.8 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EKE38520.1 - 0.0054 16.1 0.2 0.92 8.8 0.0 2.2 2 0 0 2 2 2 2 Putative esterase TCR PF03638.10 EKE38521.1 - 1.6e-06 27.8 23.5 2.6e-06 27.1 16.3 1.3 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain YqzH PF14164.1 EKE38521.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.1 3 0 0 3 3 3 0 YqzH-like protein FAD_binding_1 PF00667.15 EKE38521.1 - 1.4 8.3 5.2 1.7 8.0 3.6 1.1 1 0 0 1 1 1 0 FAD binding domain VESA1_N PF12785.2 EKE38521.1 - 5.3 5.8 13.2 8 5.2 9.1 1.2 1 1 0 1 1 1 0 Variant erythrocyte surface antigen-1 Ribosomal_L7Ae PF01248.21 EKE38522.1 - 1.5e-21 75.6 3.5 1.9e-21 75.3 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MIF4G PF02854.14 EKE38523.1 - 2.2e-11 43.5 7.4 4.1e-11 42.7 5.1 1.3 1 0 0 1 1 1 1 MIF4G domain BAR_2 PF10455.4 EKE38523.1 - 0.031 13.1 3.7 0.025 13.4 1.0 1.9 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking tRNA_NucTran2_2 PF13735.1 EKE38523.1 - 0.065 13.0 0.3 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF4163 PF13739.1 EKE38523.1 - 0.28 12.0 2.1 1.1 10.0 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) Pkinase PF00069.20 EKE38524.1 - 5.7e-45 153.4 0.0 1.3e-42 145.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38524.1 - 2.3e-26 92.4 0.1 1.1e-25 90.1 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase DUF3450 PF11932.3 EKE38525.1 - 0.0082 15.4 7.5 0.0082 15.4 5.2 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) Filament PF00038.16 EKE38525.1 - 0.93 8.9 60.5 0.42 10.0 7.5 3.3 1 1 2 3 3 3 0 Intermediate filament protein SUKH-4 PF14435.1 EKE38525.1 - 1.2 8.8 7.9 0.42 10.3 0.3 2.8 3 0 0 3 3 3 0 SUKH-4 immunity protein Lebercilin PF15619.1 EKE38525.1 - 1.5 8.1 61.3 0.2 11.0 26.1 3.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Reo_sigmaC PF04582.7 EKE38525.1 - 3.6 6.6 9.1 0.67 9.0 1.6 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Beta_helix PF13229.1 EKE38526.1 - 2.1e-33 115.2 31.1 1.7e-14 53.9 4.0 3.1 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.8 EKE38526.1 - 2.2e-23 82.6 12.9 2e-10 40.2 0.5 3.0 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 EKE38526.1 - 0.0015 17.7 12.8 0.0069 15.5 4.0 3.6 1 1 0 2 2 2 1 Protein of unknown function (DUF1565) Phage_ASH PF10554.4 EKE38526.1 - 0.043 14.1 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 Ash protein family NtA PF03146.10 EKE38526.1 - 0.44 10.1 4.7 5.5 6.6 0.0 3.5 3 1 1 4 4 4 0 Agrin NtA domain Pectate_lyase_3 PF12708.2 EKE38526.1 - 0.61 10.1 13.5 27 4.7 9.4 3.8 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pmp3 PF01679.12 EKE38527.1 - 1.8e-06 27.5 4.4 2.2e-06 27.2 3.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sas10_Utp3 PF04000.10 EKE38528.1 - 6e-08 32.7 6.0 9.7e-08 32.1 0.8 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family TPR_MLP1_2 PF07926.7 EKE38528.1 - 0.0063 16.2 7.4 0.017 14.8 0.4 2.4 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Rhabdo_glycop PF00974.13 EKE38528.1 - 0.068 11.4 0.3 0.09 10.9 0.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein TSC22 PF01166.13 EKE38528.1 - 0.076 12.9 2.5 2.3 8.2 0.2 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DNA_pack_N PF02500.10 EKE38528.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus DUF2935 PF11155.3 EKE38528.1 - 0.33 11.0 3.1 7.1 6.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) YgaB PF14182.1 EKE38528.1 - 0.5 10.6 0.1 0.5 10.6 0.1 2.8 3 0 0 3 3 3 0 YgaB-like protein HisK_N PF09385.5 EKE38528.1 - 0.73 9.4 7.5 7.9 6.0 0.0 3.2 3 1 1 4 4 4 0 Histidine kinase N terminal RasGAP PF00616.14 EKE38529.1 - 9.2e-23 80.9 1.6 9.2e-23 80.9 1.1 2.5 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase YIF1 PF03878.10 EKE38530.1 - 1.6e-39 135.5 13.2 2.1e-39 135.1 9.1 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EKE38530.1 - 0.0019 17.7 9.7 0.0035 16.8 6.7 1.5 1 0 0 1 1 1 1 Yip1 domain zf-U1 PF06220.7 EKE38531.1 - 1.2e-09 37.5 6.1 1.7e-09 37.0 4.2 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-BED PF02892.10 EKE38531.1 - 0.00048 19.8 4.9 0.00077 19.1 3.4 1.3 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_jaz PF12171.3 EKE38531.1 - 0.0057 16.7 9.0 0.21 11.7 1.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF1726 PF08351.6 EKE38531.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF3449 PF11931.3 EKE38531.1 - 0.15 11.5 1.5 0.2 11.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Adaptin_N PF01602.15 EKE38532.1 - 6.2e-70 235.9 8.9 7.7e-70 235.6 6.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EKE38532.1 - 4.4e-05 23.6 0.8 0.032 14.5 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats UPF0147 PF03685.8 EKE38532.1 - 0.003 17.3 0.1 4 7.3 0.0 3.6 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0147) Vac14_Fab1_bd PF12755.2 EKE38532.1 - 0.0041 17.4 0.4 0.45 10.9 0.1 3.0 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EKE38532.1 - 0.024 14.7 0.3 3.4 7.9 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat U3snoRNP10 PF12397.3 EKE38532.1 - 0.045 13.7 3.3 0.32 10.9 0.2 3.1 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Cnd1 PF12717.2 EKE38532.1 - 0.066 13.0 0.2 0.066 13.0 0.1 3.1 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 GpcrRhopsn4 PF10192.4 EKE38533.1 - 1.2e-06 27.9 18.2 1.2e-06 27.9 12.6 2.6 3 0 0 3 3 3 1 Rhodopsin-like GPCR transmembrane domain zinc_ribbon_4 PF13717.1 EKE38534.1 - 0.06 13.0 3.2 0.93 9.2 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Yippee-Mis18 PF03226.9 EKE38534.1 - 0.19 11.7 2.5 0.2 11.6 0.7 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc-ribbons_6 PF07191.7 EKE38534.1 - 0.22 11.3 3.0 1.8 8.4 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_5 PF13719.1 EKE38534.1 - 0.31 10.6 5.4 1 9.0 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EKE38534.1 - 1.1 9.2 6.2 7.8 6.5 0.1 2.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-HIT PF04438.11 EKE38534.1 - 1.1 8.9 10.3 4.5 6.9 0.5 2.4 2 1 0 2 2 2 0 HIT zinc finger DUF2296 PF10058.4 EKE38534.1 - 1.2 8.9 4.8 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) RNA_POL_M_15KD PF02150.11 EKE38534.1 - 1.2 8.8 5.1 24 4.7 1.4 3.2 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1 PF03811.8 EKE38534.1 - 2.1 7.8 5.3 13 5.3 0.0 2.4 2 0 0 2 2 2 0 InsA N-terminal domain zf-H2C2_2 PF13465.1 EKE38534.1 - 4.2 7.8 9.2 8.1 6.9 0.4 3.7 4 0 0 4 4 3 0 Zinc-finger double domain TFIIS_C PF01096.13 EKE38534.1 - 5.3 6.7 10.0 2.9 7.5 0.3 2.7 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Peptidase_S74 PF13884.1 EKE38535.1 - 1.5e-13 50.5 0.0 3.9e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase TspO_MBR PF03073.10 EKE38535.1 - 0.034 13.6 10.2 0.041 13.3 6.5 1.5 1 1 0 1 1 1 0 TspO/MBR family Wzy_C PF04932.10 EKE38535.1 - 1.8 8.3 6.2 0.17 11.6 0.9 1.8 2 0 0 2 2 2 0 O-Antigen ligase COPIIcoated_ERV PF07970.7 EKE38536.1 - 4.6e-33 114.7 3.0 9.5e-33 113.6 2.0 1.5 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EKE38536.1 - 1.9e-19 69.4 0.3 4.4e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Proteasome PF00227.21 EKE38537.1 - 4.9e-43 146.6 0.0 6.8e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKE38537.1 - 1.3e-14 53.1 0.9 1.8e-14 52.7 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RNA_pol_A_bac PF01000.21 EKE38537.1 - 0.072 13.2 0.1 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain WD40 PF00400.27 EKE38538.1 - 0.00014 21.6 4.4 1 9.3 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat RhoGEF PF00621.15 EKE38539.1 - 7.2e-24 84.6 11.6 7.2e-24 84.6 8.0 1.8 2 0 0 2 2 2 1 RhoGEF domain PTEN_C2 PF10409.4 EKE38540.1 - 1.7e-14 53.7 3.9 1.2e-13 50.9 2.7 2.2 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF547 PF04784.9 EKE38540.1 - 7.1e-08 32.3 0.0 1.9e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF547 Y_phosphatase PF00102.22 EKE38540.1 - 1.5e-05 24.4 0.0 3.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EKE38540.1 - 3.6e-05 23.3 0.0 0.00011 21.7 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 EKE38540.1 - 0.00015 21.2 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EKE38540.1 - 0.00052 20.3 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKE38540.1 - 0.0019 18.2 0.0 0.0049 16.9 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF869 PF05911.6 EKE38542.1 - 0.034 12.3 38.6 0.043 12.0 26.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Myb_DNA-binding PF00249.26 EKE38543.1 - 6.9e-06 26.0 0.2 5e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Herpes_UL1 PF05259.6 EKE38545.1 - 0.047 13.1 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein L DUF676 PF05057.9 EKE38546.1 - 1.2e-24 86.7 0.0 2.1e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EKE38546.1 - 0.0069 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EKE38546.1 - 0.0082 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Nitroreductase PF00881.19 EKE38547.1 - 1.4e-20 73.7 0.0 1.7e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Fer4_10 PF13237.1 EKE38547.1 - 3.7e-08 33.0 13.6 3.7e-08 33.0 9.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKE38547.1 - 6.2e-07 29.5 17.0 1.6e-06 28.2 10.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.22 EKE38547.1 - 5.5e-06 25.7 23.7 2.4e-05 23.7 3.8 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EKE38547.1 - 1.3e-05 25.4 13.8 1.3e-05 25.4 9.6 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE38547.1 - 8.1e-05 22.3 21.2 0.00061 19.5 2.9 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.1 EKE38547.1 - 9.2e-05 22.3 14.9 9.2e-05 22.3 10.3 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EKE38547.1 - 0.00021 21.0 12.9 0.00021 21.0 9.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE38547.1 - 0.00021 21.0 19.0 0.00054 19.7 2.4 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.1 EKE38547.1 - 0.0007 20.2 13.7 0.0065 17.1 0.5 2.9 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 EKE38547.1 - 0.0049 17.1 14.7 0.093 13.0 1.6 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EKE38547.1 - 0.014 15.9 3.0 0.014 15.9 2.1 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.2 EKE38547.1 - 0.026 14.8 15.1 0.11 12.8 2.9 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 EKE38547.1 - 0.15 12.5 19.8 0.81 10.1 2.3 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.1 EKE38547.1 - 2.7 8.4 16.8 3.5 8.0 3.3 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain APG6 PF04111.7 EKE38548.1 - 3.9e-10 39.2 21.8 7.5e-10 38.3 15.1 1.4 1 1 0 1 1 1 1 Autophagy protein Apg6 DXP_synthase_N PF13292.1 EKE38548.1 - 0.012 14.5 2.8 0.024 13.5 2.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase RED_N PF07808.8 EKE38548.1 - 0.81 8.8 15.2 0.031 13.4 6.0 1.9 2 0 0 2 2 2 0 RED-like protein N-terminal region Mgr1 PF08602.5 EKE38548.1 - 1.8 7.4 15.1 1.8 7.5 4.6 2.1 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit PRKCSH-like PF12999.2 EKE38548.1 - 5 6.6 13.4 0.39 10.2 5.4 2.0 2 1 0 2 2 2 0 Glucosidase II beta subunit-like IncA PF04156.9 EKE38548.1 - 8.9 5.8 14.8 3.2 7.3 8.4 1.6 2 0 0 2 2 2 0 IncA protein SH2_2 PF14633.1 EKE38549.1 - 5e-07 29.0 0.2 5.8e-07 28.7 0.2 1.0 1 0 0 1 1 1 1 SH2 domain MutS_IV PF05190.13 EKE38549.1 - 0.037 14.1 0.4 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 MutS family domain IV Peptidase_C54 PF03416.14 EKE38550.1 - 9e-20 70.9 0.0 1.3e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EKE38550.1 - 4.8e-05 22.5 0.1 0.00044 19.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase family C78 Peptidase_C54 PF03416.14 EKE38551.1 - 6.5e-14 51.7 0.1 7.8e-14 51.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase family C54 PRP38 PF03371.10 EKE38553.1 - 2.4e-48 164.0 3.9 3e-48 163.7 2.7 1.1 1 0 0 1 1 1 1 PRP38 family DSPc PF00782.15 EKE38554.1 - 2.3e-28 98.3 0.0 5e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE38554.1 - 8.3e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Gelsolin PF00626.17 EKE38554.1 - 0.00022 20.8 0.2 0.0015 18.1 0.0 2.3 2 0 0 2 2 2 1 Gelsolin repeat Init_tRNA_PT PF04179.7 EKE38554.1 - 0.024 13.5 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase CHASE PF03924.8 EKE38554.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 CHASE domain Kinetocho_Slk19 PF12709.2 EKE38556.1 - 2 8.5 5.7 16 5.6 1.1 2.4 2 0 0 2 2 2 0 Central kinetochore-associated PUF PF00806.14 EKE38557.1 - 2.7e-61 199.7 24.4 7.3e-10 37.7 0.0 9.1 8 1 0 9 9 9 8 Pumilio-family RNA binding repeat DUF445 PF04286.7 EKE38557.1 - 0.035 13.6 4.4 0.61 9.5 3.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) SapB_2 PF03489.12 EKE38557.1 - 0.08 12.9 2.4 29 4.8 0.1 4.0 4 0 0 4 4 4 0 Saposin-like type B, region 2 DUF217 PF02697.9 EKE38557.1 - 3 8.1 5.8 8.9 6.6 0.1 4.2 4 1 1 5 5 5 0 Uncharacterized ACR, COG1753 UDPGP PF01704.13 EKE38558.1 - 4.1e-132 440.6 6.2 4.9e-132 440.3 4.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase YcgL PF05166.8 EKE38558.1 - 0.045 13.8 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 YcgL domain SapB_1 PF05184.10 EKE38558.1 - 0.51 10.2 3.8 0.51 10.2 0.2 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 1 Rap_GAP PF02145.10 EKE38559.1 - 5.2e-48 162.9 0.2 9.4e-48 162.0 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP RUN PF02759.14 EKE38560.1 - 1.2 8.8 4.5 19 5.0 3.1 2.3 1 1 0 1 1 1 0 RUN domain Fe-ADH PF00465.14 EKE38561.1 - 4.3e-49 167.0 0.0 4.7e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKE38561.1 - 4.3e-08 32.7 0.6 7.6e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase BPL_LplA_LipB PF03099.14 EKE38562.1 - 1.4e-15 57.4 0.2 3e-15 56.3 0.1 1.5 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family HemY_N PF07219.8 EKE38563.1 - 0.0039 16.7 1.6 0.0048 16.4 0.7 1.4 2 0 0 2 2 2 1 HemY protein N-terminus Rax2 PF12768.2 EKE38563.1 - 0.03 13.5 3.2 0.038 13.1 2.2 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3377 PF11857.3 EKE38563.1 - 0.054 13.1 3.0 0.099 12.2 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) S1FA PF04689.8 EKE38563.1 - 0.054 13.3 0.2 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA zf-DHHC PF01529.15 EKE38563.1 - 0.09 12.1 1.0 0.11 11.8 0.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2975 PF11188.3 EKE38563.1 - 0.19 11.4 4.9 0.12 12.0 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Rifin_STEVOR PF02009.11 EKE38563.1 - 0.23 11.0 6.6 0.31 10.6 4.5 1.2 1 0 0 1 1 1 0 Rifin/stevor family Cortexin PF11057.3 EKE38563.1 - 0.25 10.9 2.4 0.5 10.0 1.6 1.4 1 1 0 1 1 1 0 Cortexin of kidney EphA2_TM PF14575.1 EKE38563.1 - 0.29 11.5 3.0 0.35 11.3 0.8 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.8 EKE38563.1 - 0.42 11.0 3.8 0.24 11.7 1.2 1.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain EVI2A PF05399.6 EKE38563.1 - 0.63 9.2 9.8 0.12 11.6 4.2 1.6 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Baculo_11_kDa PF06143.6 EKE38563.1 - 1.1 8.6 8.1 0.27 10.6 2.5 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF912 PF06024.7 EKE38563.1 - 2.4 8.2 8.1 4.5 7.3 5.6 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EKE38563.1 - 5.1 6.7 11.1 18 5.0 7.7 1.9 1 1 0 1 1 1 0 TMEM154 protein family DUF4064 PF13273.1 EKE38563.1 - 6.5 6.9 12.5 83 3.3 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) SH3_1 PF00018.23 EKE38564.1 - 1.1e-15 56.7 2.3 1.9e-15 55.9 0.1 2.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EKE38564.1 - 1.9e-15 56.1 0.2 5.8e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EKE38564.1 - 1.7e-11 43.4 0.0 6e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DUF1675 PF07897.6 EKE38564.1 - 3.8 7.2 28.8 11 5.7 20.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) tRNA-synt_His PF13393.1 EKE38565.1 - 8.8e-46 156.3 0.0 2.1e-45 155.1 0.0 1.6 2 0 0 2 2 2 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EKE38565.1 - 2.8e-17 62.8 0.0 5.7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKE38565.1 - 2.2e-10 40.3 0.2 5.5e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EKE38565.1 - 5.3e-07 28.7 0.0 3.3e-05 22.8 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EKE38565.1 - 0.00049 19.3 0.3 0.0022 17.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF3782 PF12644.2 EKE38565.1 - 3.9 7.3 8.0 9.1 6.1 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) IF4E PF01652.13 EKE38567.1 - 1.2e-46 158.3 2.1 1.4e-46 158.0 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1977 PF09320.6 EKE38568.1 - 0.029 14.6 7.8 0.039 14.1 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) cwf21 PF08312.7 EKE38568.1 - 0.61 9.9 9.0 1.4 8.7 6.2 1.6 1 1 0 1 1 1 0 cwf21 domain Fucose_iso_N2 PF07882.7 EKE38568.1 - 2.1 7.9 7.5 2.8 7.5 4.7 1.4 1 1 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Ribosomal_60s PF00428.14 EKE38569.1 - 4.2e-19 68.7 19.0 4.7e-19 68.5 13.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 EKE38569.1 - 0.0017 18.2 5.7 0.44 10.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain DUF2992 PF11208.3 EKE38569.1 - 0.011 15.6 0.4 0.013 15.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) AF1Q PF15017.1 EKE38569.1 - 0.039 13.8 1.3 0.074 12.9 0.9 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator RRP7 PF12923.2 EKE38569.1 - 0.054 13.5 2.3 0.06 13.3 1.6 1.1 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) TSP9 PF11493.3 EKE38569.1 - 0.11 13.0 1.6 0.11 12.9 0.4 1.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 DUF3408 PF11888.3 EKE38569.1 - 0.18 11.7 1.5 0.26 11.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Myc_N PF01056.13 EKE38569.1 - 0.3 10.1 2.0 0.29 10.2 1.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Cytomega_UL84 PF06284.6 EKE38569.1 - 0.36 9.1 2.7 0.35 9.2 1.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MOZART2 PF12926.2 EKE38569.1 - 3.8 7.1 6.3 2.8 7.5 1.4 2.0 1 1 1 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated PCI PF01399.22 EKE38570.1 - 9.5e-23 80.5 0.3 9.5e-23 80.5 0.2 2.5 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.6 EKE38570.1 - 1.2e-05 25.5 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 EKE38570.1 - 0.7 9.9 5.5 0.6 10.1 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_31 PF13847.1 EKE38571.1 - 8.2e-10 38.4 0.2 1e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE38571.1 - 9.3e-07 29.4 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE38571.1 - 1e-05 25.9 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKE38571.1 - 1.8e-05 25.0 0.1 2.6e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE38571.1 - 2.8e-05 24.1 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKE38571.1 - 3.8e-05 22.8 0.0 8.1e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 EKE38571.1 - 9.7e-05 21.6 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EKE38571.1 - 0.00014 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EKE38571.1 - 0.00026 20.4 0.2 0.00035 20.0 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.1 EKE38571.1 - 0.0004 20.1 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE38571.1 - 0.00048 20.5 0.0 0.00066 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EKE38571.1 - 0.00048 19.3 0.0 0.00061 18.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.8 EKE38571.1 - 0.0011 18.3 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EKE38571.1 - 0.0023 17.3 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EKE38571.1 - 0.0028 17.3 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0146 PF03686.8 EKE38571.1 - 0.0097 15.7 0.6 0.019 14.7 0.4 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0146) Ubie_methyltran PF01209.13 EKE38571.1 - 0.019 14.0 0.4 0.038 13.0 0.2 1.5 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EKE38571.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 EKE38571.1 - 0.064 12.4 0.7 0.1 11.7 0.5 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 EKE38571.1 - 0.093 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cullin_Nedd8 PF10557.4 EKE38572.1 - 0.00073 19.3 3.1 0.00073 19.3 2.2 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain Arm PF00514.18 EKE38573.1 - 3.1e-06 26.7 2.7 4.7 7.1 0.0 6.5 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Suppressor_APC PF11414.3 EKE38574.1 - 0.0015 18.2 0.1 0.0036 17.0 0.1 1.7 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein Sec20 PF03908.8 EKE38574.1 - 0.0026 17.4 2.7 0.0027 17.3 0.2 2.1 2 1 0 2 2 2 1 Sec20 V-SNARE_C PF12352.3 EKE38574.1 - 0.0028 17.6 0.8 0.0066 16.4 0.5 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus CCDC155 PF14662.1 EKE38574.1 - 0.012 15.2 5.0 0.025 14.1 3.3 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 TBPIP PF07106.8 EKE38574.1 - 0.026 14.0 0.7 0.026 14.0 0.5 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Troponin PF00992.15 EKE38574.1 - 0.04 13.9 6.2 0.062 13.3 4.3 1.4 1 0 0 1 1 1 0 Troponin Atg14 PF10186.4 EKE38574.1 - 0.093 11.6 1.6 0.11 11.3 1.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Transcrip_act PF04949.8 EKE38574.1 - 0.11 12.1 8.7 0.15 11.7 5.1 1.9 1 1 1 2 2 2 0 Transcriptional activator DUF3802 PF12290.3 EKE38574.1 - 3.6 7.9 7.5 8.1 6.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) Phage_Gp23 PF10669.4 EKE38574.1 - 5.9 7.0 9.6 3.9 7.6 3.9 2.2 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) Dopey_N PF04118.9 EKE38575.1 - 3.6e-25 88.3 0.0 4.4e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Dopey, N-terminal Swi3 PF07962.7 EKE38575.1 - 0.00079 19.0 0.6 0.0011 18.4 0.4 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 PLA2_B PF01735.13 EKE38575.1 - 0.029 12.5 0.0 0.033 12.3 0.0 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Prp18 PF02840.10 EKE38575.1 - 0.072 12.9 0.3 0.15 11.8 0.2 1.4 1 1 0 1 1 1 0 Prp18 domain Glyco_hydro_67C PF07477.7 EKE38575.1 - 0.16 11.3 0.2 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus Dopey_N PF04118.9 EKE38576.1 - 4.6e-17 61.7 2.5 4.6e-17 61.7 1.7 2.2 2 0 0 2 2 2 2 Dopey, N-terminal eIF2A PF08662.6 EKE38577.1 - 4.5e-11 42.8 5.4 7e-09 35.6 0.2 4.5 1 1 4 5 5 5 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EKE38577.1 - 0.0034 16.9 1.0 0.0074 15.8 0.2 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE38577.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IBB PF01749.15 EKE38577.1 - 0.2 11.8 6.8 0.52 10.5 4.7 1.7 1 0 0 1 1 1 0 Importin beta binding domain WD40 PF00400.27 EKE38577.1 - 0.67 9.9 3.5 44 4.1 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat HAUS6_N PF14661.1 EKE38578.1 - 0.19 11.0 16.2 0.19 11.0 11.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fib_alpha PF08702.5 EKE38578.1 - 0.46 10.6 8.6 0.085 12.9 2.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 EKE38578.1 - 0.75 9.3 19.8 0.79 9.2 13.8 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF676 PF05057.9 EKE38578.1 - 1.4 8.1 4.8 1.7 7.8 3.3 1.0 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Occludin_ELL PF07303.8 EKE38578.1 - 1.6 9.5 13.6 2 9.1 9.4 1.1 1 0 0 1 1 1 0 Occludin homology domain ADIP PF11559.3 EKE38578.1 - 1.9 8.3 18.8 5.8 6.8 12.8 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EKE38578.1 - 2.2 8.0 21.9 2.8 7.7 15.2 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1204 PF06721.6 EKE38578.1 - 2.7 7.1 14.9 2.9 7.0 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) MAP7 PF05672.6 EKE38578.1 - 5.5 6.3 39.2 7.2 5.9 27.2 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Exonuc_VII_L PF02601.10 EKE38578.1 - 5.8 6.0 10.8 6.7 5.7 7.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AA_permease_N PF08403.5 EKE38578.1 - 7.3 5.9 5.8 41 3.5 4.0 2.0 1 1 0 1 1 1 0 Amino acid permease N-terminal Merozoite_SPAM PF07133.6 EKE38578.1 - 8 6.3 32.7 8.4 6.2 22.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Gelsolin PF00626.17 EKE38579.1 - 1.3e-53 178.6 4.7 1.6e-10 40.5 0.0 7.7 7 0 0 7 7 7 7 Gelsolin repeat LRR_8 PF13855.1 EKE38579.1 - 2e-24 85.1 57.6 3.4e-08 33.1 2.1 4.5 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EKE38579.1 - 5.1e-21 73.8 58.8 3.1e-06 26.6 5.1 7.0 1 1 5 8 8 8 8 Leucine Rich repeats (2 copies) VHP PF02209.14 EKE38579.1 - 1.3e-14 53.5 1.7 3.9e-14 52.0 1.2 1.9 1 0 0 1 1 1 1 Villin headpiece domain LRR_1 PF00560.28 EKE38579.1 - 1.9e-07 30.1 46.9 0.9 9.8 0.3 10.2 10 0 0 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 EKE38579.1 - 1.9e-05 24.0 37.0 2.1 8.8 0.2 10.2 10 0 0 10 10 10 4 Leucine rich repeat LIM PF00412.17 EKE38580.1 - 6.1e-15 55.0 26.1 9.9e-11 41.5 4.3 2.5 2 1 0 2 2 2 2 LIM domain TNFR_c6 PF00020.13 EKE38580.1 - 2.8 8.0 30.7 0.92 9.6 0.7 5.0 4 2 1 5 5 5 0 TNFR/NGFR cysteine-rich region DUF2318 PF10080.4 EKE38580.1 - 6.8 6.5 23.9 2 8.2 1.0 2.6 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) LCAT PF02450.10 EKE38582.1 - 1.3e-44 152.7 2.6 2.5e-38 132.0 1.0 2.3 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EKE38582.1 - 8.6e-05 21.9 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EKE38582.1 - 8.8e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EKE38582.1 - 0.00055 19.8 0.0 0.00085 19.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EKE38582.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EKE38582.1 - 0.0064 16.2 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE38582.1 - 0.012 15.1 0.0 0.048 13.2 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Lipase_2 PF01674.13 EKE38582.1 - 0.02 14.2 0.1 0.04 13.2 0.0 1.5 2 0 0 2 2 2 0 Lipase (class 2) Ser_hydrolase PF06821.8 EKE38582.1 - 0.054 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase CbiX PF01903.12 EKE38582.1 - 0.068 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 CbiX Pkinase_Tyr PF07714.12 EKE38583.1 - 6.7e-31 107.2 1.2 1.5e-30 106.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38583.1 - 1.5e-28 99.6 0.2 3.6e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L32p PF01783.18 EKE38584.1 - 0.049 13.8 0.2 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal L32p protein family ParB PF08775.5 EKE38586.1 - 1.2 9.4 8.0 0.52 10.6 3.3 1.9 2 1 0 2 2 2 0 ParB family S4_2 PF13275.1 EKE38587.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 S4 domain mIF3 PF14877.1 EKE38588.1 - 0.056 12.8 1.2 0.073 12.4 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial translation initiation factor FAM177 PF14774.1 EKE38588.1 - 0.14 12.0 1.3 0.58 10.0 0.2 2.1 2 0 0 2 2 2 0 FAM177 family DNA_pol3_a_NII PF11490.3 EKE38588.1 - 5.1 6.7 13.7 0.49 10.0 0.1 3.4 4 0 0 4 4 4 0 DNA polymerase III polC-type N-terminus II DUF743 PF05332.6 EKE38590.1 - 0.026 14.4 0.3 0.053 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF743) DUF1533 PF07550.6 EKE38590.1 - 1.8 8.5 6.4 1.2 9.1 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1533) SMC_Nse1 PF07574.8 EKE38591.1 - 2.4e-07 30.5 1.7 3.7e-07 29.9 1.0 1.5 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-HC5HC2H PF13771.1 EKE38591.1 - 0.00079 19.5 3.3 0.002 18.2 2.3 1.8 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-RING-like PF08746.6 EKE38591.1 - 0.0012 18.7 6.0 0.0023 17.8 4.1 1.5 1 0 0 1 1 1 1 RING-like domain Orthopox_F7 PF05813.7 EKE38591.1 - 0.005 16.6 0.1 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 Orthopoxvirus F7 protein RloB PF13707.1 EKE38591.1 - 0.018 14.7 0.5 0.025 14.2 0.4 1.3 1 0 0 1 1 1 0 RloB-like protein zf-HC5HC2H_2 PF13832.1 EKE38591.1 - 0.021 14.8 2.1 0.039 13.9 1.5 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain COG2 PF06148.6 EKE38591.1 - 0.039 13.8 2.2 0.091 12.6 1.2 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 LAGLIDADG_1 PF00961.14 EKE38591.1 - 0.062 13.8 1.3 0.15 12.6 0.9 1.8 1 1 0 1 1 1 0 LAGLIDADG endonuclease Prok-RING_1 PF14446.1 EKE38591.1 - 0.27 10.9 4.5 0.8 9.4 3.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 CitX PF03802.9 EKE38591.1 - 0.92 8.9 5.2 0.076 12.4 0.2 1.8 2 1 0 2 2 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase PHD PF00628.24 EKE38591.1 - 6.7 6.4 7.8 15 5.4 5.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.2 EKE38591.1 - 8.8 6.5 7.4 3.6 7.7 3.0 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger Pkinase PF00069.20 EKE38592.1 - 7.7e-61 205.5 2.0 8.1e-60 202.1 1.4 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38592.1 - 2.6e-26 92.2 0.7 5.3e-19 68.3 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EKE38592.1 - 2.1e-05 24.9 1.2 5.2e-05 23.6 0.9 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EKE38592.1 - 0.00096 18.1 0.7 0.01 14.8 0.0 2.7 1 1 2 3 3 3 1 Kinase-like APH PF01636.18 EKE38592.1 - 0.0014 18.4 0.2 0.012 15.3 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EKE38592.1 - 0.0077 15.1 0.1 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EKE38592.1 - 0.014 14.4 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_14 PF13173.1 EKE38593.1 - 0.0067 16.3 0.3 0.037 13.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain Yip1 PF04893.12 EKE38594.1 - 3.9e-07 29.7 25.5 9.5e-07 28.4 17.5 1.6 1 1 0 1 1 1 1 Yip1 domain DUF898 PF05987.8 EKE38594.1 - 8.5 5.1 17.3 9.3e+02 -1.6 11.6 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) RhoGEF PF00621.15 EKE38595.1 - 0.002 18.0 1.1 0.0025 17.6 0.8 1.1 1 0 0 1 1 1 1 RhoGEF domain Lebercilin PF15619.1 EKE38595.1 - 0.003 17.0 1.9 0.0033 16.8 1.3 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Aminotran_1_2 PF00155.16 EKE38595.1 - 0.057 12.3 0.1 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DivIVA PF05103.8 EKE38595.1 - 0.12 12.4 4.2 0.14 12.1 2.1 1.6 1 1 1 2 2 2 0 DivIVA protein LAMTOR PF15454.1 EKE38595.1 - 0.17 12.1 1.2 0.28 11.5 0.8 1.3 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF572 PF04502.8 EKE38596.1 - 8.8e-60 202.6 25.9 1e-59 202.3 18.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zinc_ribbon_5 PF13719.1 EKE38596.1 - 0.011 15.3 1.3 2.4 7.8 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF2396 PF09654.5 EKE38596.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) zinc_ribbon_4 PF13717.1 EKE38596.1 - 0.02 14.5 1.5 4.1 7.1 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain C1_3 PF07649.7 EKE38596.1 - 0.05 13.6 8.4 1.9 8.5 0.1 2.8 3 0 0 3 3 3 0 C1-like domain Mu-like_Com PF10122.4 EKE38596.1 - 0.11 11.5 2.5 0.54 9.3 0.3 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-FPG_IleRS PF06827.9 EKE38596.1 - 0.39 10.4 3.5 0.55 9.9 0.3 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-ribbon_3 PF13248.1 EKE38596.1 - 0.5 9.6 2.7 0.97 8.7 0.4 2.4 2 1 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EKE38596.1 - 2.6 7.4 10.1 0.16 11.2 1.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding C1_4 PF07975.7 EKE38596.1 - 2.7 8.0 6.6 0.63 10.0 1.5 2.3 2 1 0 2 2 2 0 TFIIH C1-like domain zf-PHD-like PF15446.1 EKE38596.1 - 6.1 6.0 10.8 0.41 9.9 0.6 3.1 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Pkinase_Tyr PF07714.12 EKE38597.1 - 7.9e-49 166.0 0.0 1.2e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38597.1 - 6.7e-48 163.0 0.1 5.4e-47 160.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain VSP PF03302.8 EKE38597.1 - 7.3 5.1 198.1 0.03 12.9 27.3 8.0 1 1 4 5 5 5 0 Giardia variant-specific surface protein UNC45-central PF11701.3 EKE38598.1 - 0.3 10.7 6.1 0.6 9.7 0.8 3.8 1 1 2 4 4 4 0 Myosin-binding striated muscle assembly central DUF1242 PF06842.7 EKE38599.1 - 7.1e-09 35.0 8.3 4.2e-08 32.5 5.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1242) NIF PF03031.13 EKE38601.1 - 1.1e-31 109.6 2.9 1.3e-31 109.3 2.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EKE38601.1 - 6.9e-09 36.1 0.8 1.2e-06 28.8 0.0 2.2 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EKE38601.1 - 0.0025 17.4 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Acid Phosphatase HAD PF12710.2 EKE38601.1 - 0.0062 16.7 1.5 0.22 11.6 1.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 EKE38601.1 - 0.0093 14.9 5.1 0.62 9.0 0.4 2.9 1 1 1 3 3 3 1 Protein of unknown function (DUF2608) PNK3P PF08645.6 EKE38601.1 - 0.059 12.8 0.5 0.11 11.9 0.3 1.5 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.21 EKE38601.1 - 0.065 13.6 0.6 4.4 7.6 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DnaJ PF00226.26 EKE38602.1 - 8.2e-29 99.1 2.9 1.3e-28 98.5 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EKE38602.1 - 7.1e-25 86.7 1.3 9e-21 73.5 0.1 2.8 2 1 0 2 2 2 2 DnaJ C terminal domain GldM_C PF12080.3 EKE38602.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 GldM C-terminal domain Pkinase PF00069.20 EKE38603.1 - 4.1e-54 183.4 0.0 7e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38603.1 - 1.3e-52 178.4 0.0 2.3e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mid2 PF04478.7 EKE38603.1 - 0.0068 15.8 2.4 0.017 14.5 1.7 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Tetraspannin PF00335.15 EKE38603.1 - 0.0071 15.6 3.3 0.015 14.6 2.3 1.5 1 0 0 1 1 1 1 Tetraspanin family MLANA PF14991.1 EKE38603.1 - 0.038 14.0 0.9 0.1 12.6 0.6 1.7 1 0 0 1 1 1 0 Protein melan-A SKG6 PF08693.5 EKE38603.1 - 0.076 12.3 4.8 0.17 11.2 3.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.18 EKE38603.1 - 0.32 10.6 0.0 0.63 9.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family OppC_N PF12911.2 EKE38603.1 - 6.6 6.1 10.2 6.5 6.2 5.4 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Peptidase_S41 PF03572.13 EKE38604.1 - 0.036 13.4 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S41 DUF2045 PF09741.4 EKE38605.1 - 0.05 12.7 0.9 0.087 11.9 0.7 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) RhoGEF PF00621.15 EKE38606.1 - 2.7e-28 99.0 0.8 2.7e-28 99.0 0.5 2.0 3 0 0 3 3 3 1 RhoGEF domain CNP1 PF08750.6 EKE38606.1 - 0.12 12.0 1.1 0.28 10.8 0.8 1.6 1 0 0 1 1 1 0 CNP1-like family RhoGAP PF00620.22 EKE38608.1 - 2.3e-22 79.2 0.7 2.3e-22 79.2 0.5 2.2 2 0 0 2 2 2 1 RhoGAP domain CDC48_N PF02359.13 EKE38610.1 - 7e-15 54.7 0.1 2e-13 50.0 0.1 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EKE38610.1 - 4.5e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Adaptin_N PF01602.15 EKE38612.1 - 4e-63 213.5 42.9 5e-63 213.2 29.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Not1 PF04054.10 EKE38613.1 - 5.8e-12 45.1 26.9 2.3e-10 39.8 7.0 3.6 1 1 2 3 3 3 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EKE38613.1 - 6.2e-07 29.1 5.3 6.2e-07 29.1 3.7 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) UCH PF00443.24 EKE38614.1 - 5.4e-44 150.3 3.5 5.4e-44 150.3 2.4 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE38614.1 - 8.2e-19 68.1 2.1 8.2e-19 68.1 1.4 3.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ras PF00071.17 EKE38617.1 - 3.4e-55 185.8 0.0 4e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38617.1 - 2.5e-17 63.4 0.0 6.3e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE38617.1 - 3.1e-09 36.3 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE38617.1 - 0.008 15.6 0.0 0.043 13.2 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE38617.1 - 0.038 13.1 0.0 0.091 11.8 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Peptidase_A22B PF04258.8 EKE38618.1 - 1.1e-23 84.0 29.9 6.4e-23 81.6 20.7 1.9 1 1 0 1 1 1 1 Signal peptide peptidase Piwi PF02171.12 EKE38619.1 - 5.5e-16 58.3 1.5 5.5e-16 58.3 1.1 1.8 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 EKE38619.1 - 0.00011 21.4 0.4 0.00029 20.1 0.3 1.6 1 0 0 1 1 1 1 PAZ domain DinB_2 PF12867.2 EKE38620.1 - 0.094 13.0 0.0 0.69 10.2 0.0 2.1 2 0 0 2 2 2 0 DinB superfamily SpecificRecomb PF10136.4 EKE38620.1 - 0.11 10.5 0.1 0.17 9.8 0.1 1.3 1 0 0 1 1 1 0 Site-specific recombinase NPV_P10 PF05531.7 EKE38620.1 - 3.3 8.0 7.1 5.8 7.2 0.7 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DivIVA PF05103.8 EKE38620.1 - 8 6.5 14.8 0.46 10.5 3.7 2.7 2 1 1 3 3 3 0 DivIVA protein Nup96 PF12110.3 EKE38622.1 - 0.00081 18.5 0.4 0.0011 18.1 0.2 1.1 1 0 0 1 1 1 1 Nuclear protein 96 DSBA PF01323.15 EKE38622.1 - 0.08 12.4 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain L27_N PF09060.5 EKE38622.1 - 0.48 10.2 3.2 0.51 10.1 0.7 2.2 2 1 0 2 2 2 0 L27_N Integrase_AP2 PF14657.1 EKE38623.1 - 0.056 13.2 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain Rhodanese PF00581.15 EKE38624.1 - 2.3e-10 40.8 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF1681 PF07933.9 EKE38625.1 - 2.1e-45 154.1 0.0 2.9e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) InvH PF04741.7 EKE38625.1 - 0.18 11.6 0.8 0.34 10.7 0.6 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein MMR_HSR1 PF01926.18 EKE38626.1 - 1.9e-10 40.7 1.7 2.5e-10 40.3 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.13 EKE38626.1 - 5.1e-09 35.5 0.1 0.0016 17.5 0.0 2.6 2 0 0 2 2 2 2 Septin DUF258 PF03193.11 EKE38626.1 - 2.6e-06 26.7 0.1 6e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKE38626.1 - 5.7e-05 23.4 0.1 0.00037 20.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter FeoB_N PF02421.13 EKE38626.1 - 0.00019 20.7 0.2 0.00082 18.6 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EKE38626.1 - 0.00025 21.0 0.0 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Arf PF00025.16 EKE38626.1 - 0.0013 17.9 0.2 0.012 14.8 0.1 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF815 PF05673.8 EKE38626.1 - 0.0015 17.5 0.0 0.0048 15.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Gtr1_RagA PF04670.7 EKE38626.1 - 0.0015 17.6 1.1 0.004 16.3 0.1 2.3 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EKE38626.1 - 0.0021 17.5 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.17 EKE38626.1 - 0.0022 17.4 1.6 0.034 13.5 0.4 3.0 2 1 0 2 2 2 1 Ras family Miro PF08477.8 EKE38626.1 - 0.0023 18.4 1.4 0.0047 17.4 0.2 2.2 2 1 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 EKE38626.1 - 0.0045 17.1 0.1 0.16 12.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IIGP PF05049.8 EKE38626.1 - 0.0063 15.3 1.2 0.036 12.8 0.0 2.4 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EKE38626.1 - 0.0085 15.2 3.1 0.013 14.6 0.1 2.5 3 0 0 3 3 3 1 AIG1 family FtsK_SpoIIIE PF01580.13 EKE38626.1 - 0.015 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EKE38626.1 - 0.015 15.4 0.1 0.051 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EKE38626.1 - 0.021 14.6 3.1 0.042 13.6 0.3 2.6 3 1 0 3 3 2 0 Dynamin family AAA_10 PF12846.2 EKE38626.1 - 0.052 12.9 0.1 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 EKE38626.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 EKE38626.1 - 0.099 11.5 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EKE38626.1 - 0.18 12.0 14.9 2.4 8.4 10.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKE38626.1 - 0.32 10.9 2.7 0.34 10.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 EKE38626.1 - 0.34 10.6 4.8 0.35 10.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EKE38626.1 - 0.42 10.3 5.1 0.38 10.4 0.1 3.1 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Pkinase PF00069.20 EKE38627.1 - 2.1e-22 79.5 0.2 3.2e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38627.1 - 2.2e-22 79.3 0.1 3.2e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Noc2 PF03715.8 EKE38628.1 - 2.8e-42 144.6 11.7 4e-42 144.0 8.1 1.2 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.7 EKE38628.1 - 0.0011 16.9 2.7 0.0011 16.9 1.9 2.5 3 0 0 3 3 3 1 Nop14-like family MecA_N PF05223.6 EKE38628.1 - 0.11 12.5 3.4 0.11 12.5 0.1 2.6 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain PRMT5 PF05185.11 EKE38629.1 - 3.4e-14 52.6 0.2 4.9e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 EKE38629.1 - 1.3e-12 47.4 0.0 1.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EKE38629.1 - 6.3e-12 45.3 0.2 1.1e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE38629.1 - 2.2e-08 34.4 0.0 4.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE38629.1 - 5.8e-08 32.6 0.0 9.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE38629.1 - 1.2e-07 31.2 0.0 2.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EKE38629.1 - 2.4e-07 30.5 0.3 4.3e-07 29.7 0.2 1.6 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EKE38629.1 - 3.3e-07 30.3 0.0 6.1e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE38629.1 - 4.9e-07 30.3 0.0 9.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EKE38629.1 - 0.00032 19.8 0.1 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EKE38629.1 - 0.00037 20.9 0.0 0.00081 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EKE38629.1 - 0.00039 19.6 0.2 0.00081 18.5 0.1 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EKE38629.1 - 0.00084 20.1 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKE38629.1 - 0.0009 19.2 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EKE38629.1 - 0.002 18.4 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EKE38629.1 - 0.0044 16.6 0.1 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 EKE38629.1 - 0.0098 15.3 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 EKE38629.1 - 0.0099 14.6 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 EKE38629.1 - 0.032 13.9 0.1 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EKE38629.1 - 0.067 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NGP1NT PF08153.7 EKE38630.1 - 0.068 13.1 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 NGP1NT (NUC091) domain CAP18_C PF12153.3 EKE38630.1 - 0.098 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Rep_fac-A_C PF08646.5 EKE38631.1 - 1.2e-31 109.3 6.1 1.4e-31 109.1 2.5 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EKE38631.1 - 6e-10 38.8 8.5 5.2e-07 29.4 0.2 4.4 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain zinc_ribbon_2 PF13240.1 EKE38631.1 - 0.00015 21.0 3.3 0.00032 20.0 2.3 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 EKE38631.1 - 0.0032 16.6 1.0 0.0072 15.5 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EKE38631.1 - 0.0034 17.1 0.4 0.0076 16.0 0.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc-ribbons_6 PF07191.7 EKE38631.1 - 0.041 13.6 1.7 0.098 12.4 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbons UPF0547 PF10571.4 EKE38631.1 - 0.31 10.7 2.6 0.62 9.8 1.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 LRR_5 PF13306.1 EKE38633.1 - 1.4e-45 154.1 19.6 8.7e-27 93.3 5.3 3.1 2 2 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38633.1 - 1.2e-14 53.7 5.3 0.00034 20.2 0.1 4.2 4 1 1 5 5 5 3 Leucine rich repeat Pentapeptide_4 PF13599.1 EKE38635.1 - 0.017 14.9 0.1 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) LSM PF01423.17 EKE38638.1 - 0.08 12.5 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 LSM domain DUF788 PF05620.6 EKE38639.1 - 2.2e-26 92.7 4.4 2.4e-26 92.5 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) 60KD_IMP PF02096.15 EKE38639.1 - 0.031 13.9 1.5 0.042 13.5 1.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Bap31 PF05529.7 EKE38639.1 - 0.41 10.0 0.1 0.41 10.0 0.0 2.1 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like 7tm_1 PF00001.16 EKE38639.1 - 0.47 9.5 6.8 3.4 6.7 1.5 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Lactamase_B PF00753.22 EKE38640.1 - 1.1e-23 83.8 0.4 1.4e-23 83.5 0.3 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE38640.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Maelstrom PF13017.1 EKE38641.1 - 6.3e-62 208.8 17.1 7.6e-34 117.0 1.8 4.2 4 1 0 4 4 4 2 piRNA pathway germ-plasm component RNase_T PF00929.19 EKE38641.1 - 0.095 12.9 0.1 0.095 12.9 0.1 4.2 4 2 1 5 5 5 0 Exonuclease TRAPPC-Trs85 PF12739.2 EKE38642.1 - 1.2e-06 27.4 0.0 2.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_8 PF13181.1 EKE38642.1 - 4.5e-05 22.9 0.4 0.00019 20.9 0.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKE38642.1 - 0.0026 17.3 0.1 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKE38642.1 - 0.0074 15.9 0.5 0.019 14.5 0.1 1.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EKE38642.1 - 0.0079 16.0 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKE38642.1 - 0.0092 15.7 0.1 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat RPN7 PF10602.4 EKE38642.1 - 0.015 14.7 0.1 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_12 PF13424.1 EKE38642.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat AMP-binding PF00501.23 EKE38644.1 - 4e-72 242.9 0.0 4.8e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKE38644.1 - 0.12 13.3 0.0 0.49 11.3 0.0 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Solute_trans_a PF03619.11 EKE38645.1 - 6e-27 94.6 22.3 8.1e-27 94.2 15.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HAD_2 PF13419.1 EKE38646.1 - 1.5e-13 51.3 0.0 1.7e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE38646.1 - 0.00058 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EKE38646.1 - 0.002 18.6 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE38646.1 - 0.096 12.8 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Crp PF00325.15 EKE38646.1 - 0.12 11.8 0.3 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Mito_carr PF00153.22 EKE38647.1 - 5.6e-06 25.9 0.4 1.4e-05 24.6 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial carrier protein Ig_Tie2_1 PF10430.4 EKE38647.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 DUF483 PF04467.7 EKE38647.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF483) PIP5K PF01504.13 EKE38648.1 - 6.1e-63 212.2 13.8 5.6e-62 209.1 9.6 2.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Mem_trans PF03547.13 EKE38648.1 - 2.2 6.5 7.7 3.3 5.8 5.3 1.4 1 0 0 1 1 1 0 Membrane transport protein DUF2217 PF10265.4 EKE38648.1 - 3.8 6.1 16.9 5.5 5.6 11.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SOBP PF15279.1 EKE38648.1 - 6.3 7.0 13.6 11 6.2 9.4 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.5 EKE38648.1 - 7.1 4.9 10.9 10 4.3 7.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lactamase_B_2 PF12706.2 EKE38649.1 - 6e-20 71.6 3.8 7.5e-20 71.3 2.6 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKE38649.1 - 1.1e-13 51.3 2.0 1.5e-13 50.8 1.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EKE38649.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease PDEase_II PF02112.10 EKE38649.1 - 0.057 12.3 8.9 8.3 5.2 6.1 2.5 1 1 0 1 1 1 0 cAMP phosphodiesterases class-II zf-RING_2 PF13639.1 EKE38650.1 - 9e-14 51.0 14.5 1.8e-13 50.0 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKE38650.1 - 2.8e-07 30.5 11.2 6e-07 29.4 7.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKE38650.1 - 1.5e-05 24.5 16.0 3e-05 23.5 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE38650.1 - 2.8e-05 24.0 16.4 6.1e-05 22.9 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE38650.1 - 4.7e-05 23.0 13.1 9.1e-05 22.1 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EKE38650.1 - 0.0002 20.9 5.9 0.0002 20.9 4.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EKE38650.1 - 0.00026 20.7 6.2 0.00042 20.1 4.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EKE38650.1 - 0.00049 19.6 12.6 0.001 18.6 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EKE38650.1 - 0.068 12.7 0.5 0.068 12.7 0.4 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Inhibitor_I67 PF11405.3 EKE38650.1 - 0.13 12.2 3.4 0.12 12.4 0.9 2.0 2 0 0 2 2 2 0 Bromelain inhibitor VI Rad50_zn_hook PF04423.9 EKE38650.1 - 0.57 9.6 4.5 1 8.8 0.5 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.3 EKE38650.1 - 4.2 7.4 11.2 20 5.2 7.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain UQ_con PF00179.21 EKE38651.1 - 3.4e-43 146.4 0.2 3.8e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EKE38651.1 - 0.00061 19.6 0.2 0.00094 19.0 0.1 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EKE38651.1 - 0.0013 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EKE38651.1 - 0.033 13.8 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Ras PF00071.17 EKE38653.1 - 1.4e-39 135.0 0.0 1.7e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38653.1 - 1.2e-15 58.0 0.0 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38653.1 - 1.8e-13 50.1 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE38653.1 - 6.3e-05 22.2 0.0 8.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EKE38653.1 - 0.0022 17.5 0.0 0.054 12.9 0.0 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EKE38653.1 - 0.0074 15.7 0.2 0.03 13.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE38653.1 - 0.0082 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EKE38653.1 - 0.031 13.8 0.0 2.3 7.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EKE38653.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Mito_fiss_Elm1 PF06258.6 EKE38653.1 - 0.065 12.1 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 cobW PF02492.14 EKE38653.1 - 0.068 12.6 0.1 2.3 7.6 0.0 2.5 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EKE38653.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Abhydrolase_5 PF12695.2 EKE38653.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family RasGEF PF00617.14 EKE38654.1 - 1.9e-08 34.2 1.7 4.5e-08 33.0 1.2 1.6 1 0 0 1 1 1 1 RasGEF domain TAFH PF07531.9 EKE38654.1 - 0.0012 18.4 0.1 0.0048 16.5 0.0 2.0 1 0 0 1 1 1 1 NHR1 homology to TAF DUF4211 PF13926.1 EKE38654.1 - 0.058 12.8 1.4 0.18 11.2 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4211) VPS9 PF02204.13 EKE38656.1 - 6.6e-09 35.7 0.4 4.4e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Arf PF00025.16 EKE38656.1 - 2e-08 33.7 0.0 1.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EKE38656.1 - 0.0017 18.8 0.2 0.011 16.2 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 EKE38656.1 - 0.0044 16.0 3.4 0.0095 14.9 0.0 2.3 2 0 0 2 2 2 1 Septin AAA_28 PF13521.1 EKE38656.1 - 0.0053 16.7 0.8 0.011 15.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKE38656.1 - 0.0055 16.7 0.2 0.024 14.6 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EKE38656.1 - 0.0089 14.9 1.7 0.011 14.6 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 EKE38656.1 - 0.012 15.2 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EKE38656.1 - 0.022 13.9 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EKE38656.1 - 0.033 14.3 0.8 0.73 10.0 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKE38656.1 - 0.048 13.7 0.1 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKE38656.1 - 0.065 12.9 11.0 0.26 10.9 0.1 3.6 5 0 0 5 5 5 0 Archaeal ATPase AAA_17 PF13207.1 EKE38656.1 - 0.076 13.8 0.0 0.33 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKE38656.1 - 0.14 11.5 0.0 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EKE38656.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.4 2 1 0 2 2 1 0 ABC transporter AAA_18 PF13238.1 EKE38656.1 - 0.29 11.4 2.9 2.2 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Rap1_C PF11626.3 EKE38657.1 - 2.3e-12 46.6 0.0 3.3e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain UBA PF00627.26 EKE38657.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain Avl9 PF09794.4 EKE38658.1 - 4.7e-21 74.7 2.9 1.2e-18 66.8 2.0 2.1 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EKE38658.1 - 0.00077 19.1 0.7 0.003 17.2 0.5 2.0 1 1 0 1 1 1 1 Stabilization of polarity axis RabGAP-TBC PF00566.13 EKE38659.1 - 3.7e-37 127.8 3.9 3.7e-37 127.8 2.7 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Baculo_PEP_C PF04513.7 EKE38659.1 - 0.17 11.6 0.5 1 9.2 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PX PF00787.19 EKE38660.1 - 3.4e-10 39.6 0.1 6.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 PX domain RPAP3_C PF13877.1 EKE38660.1 - 0.1 12.5 0.2 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 GATase_7 PF13537.1 EKE38661.1 - 0.0048 16.6 0.1 0.0066 16.1 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3942 PF13078.1 EKE38661.1 - 0.0085 16.1 0.9 0.014 15.4 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3942) LXG PF04740.7 EKE38661.1 - 0.0095 15.7 3.8 0.019 14.7 0.3 2.0 1 1 1 2 2 2 2 LXG domain of WXG superfamily DUF607 PF04678.8 EKE38661.1 - 0.014 15.3 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 hEGF PF12661.2 EKE38662.1 - 0.043 13.9 14.4 9.4 6.5 0.2 5.1 4 0 0 4 4 4 0 Human growth factor-like EGF AIG1 PF04548.11 EKE38664.1 - 1.5e-11 43.8 0.3 1.6e-11 43.7 0.2 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EKE38664.1 - 7.3e-07 29.1 0.3 7.8e-07 29.0 0.2 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKE38664.1 - 5.1e-05 22.5 0.5 0.0001 21.5 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EKE38664.1 - 0.0019 18.0 1.7 0.35 10.6 0.0 2.1 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EKE38664.1 - 0.008 15.6 0.2 0.21 10.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EKE38664.1 - 0.072 12.3 0.2 0.08 12.2 0.2 1.0 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 EKE38664.1 - 0.087 12.0 0.1 0.094 11.9 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EKE38664.1 - 0.1 12.1 0.5 0.16 11.5 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EKE38664.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.11 EKE38665.1 - 1.4e-18 66.7 0.1 2.4e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EKE38665.1 - 6.6e-11 42.1 0.1 1.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKE38665.1 - 1.5e-06 27.4 0.3 3.6e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EKE38665.1 - 6.8e-05 22.0 0.5 0.00017 20.7 0.4 1.6 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 EKE38665.1 - 0.0012 18.6 7.0 0.35 10.6 1.0 2.8 3 0 0 3 3 3 2 Dynamin family Miro PF08477.8 EKE38665.1 - 0.0074 16.7 1.4 0.012 16.0 0.0 2.1 3 0 0 3 3 2 1 Miro-like protein Gtr1_RagA PF04670.7 EKE38665.1 - 0.013 14.7 0.3 0.027 13.5 0.2 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE38665.1 - 0.016 15.3 0.1 0.047 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EKE38665.1 - 0.06 12.6 0.4 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.17 EKE38665.1 - 0.065 12.6 5.9 0.058 12.7 0.4 3.0 3 1 0 3 3 3 0 Ras family T2SE PF00437.15 EKE38665.1 - 0.16 10.8 0.6 0.29 9.9 0.4 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EKE38665.1 - 0.3 11.3 4.5 0.11 12.7 0.7 2.0 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 EKE38665.1 - 0.41 10.2 2.0 0.77 9.3 1.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMEM164 PF14808.1 EKE38666.1 - 2.3e-15 56.4 19.0 3.1e-15 56.0 13.2 1.1 1 0 0 1 1 1 1 TMEM164 family Pmp3 PF01679.12 EKE38667.1 - 8.7e-11 41.3 8.1 9.4e-11 41.2 5.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator STE3 PF02076.10 EKE38667.1 - 0.13 11.3 2.5 0.14 11.2 1.7 1.0 1 0 0 1 1 1 0 Pheromone A receptor DUF4131 PF13567.1 EKE38667.1 - 0.29 10.5 2.8 0.33 10.3 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) C6_DPF PF10170.4 EKE38668.1 - 0.029 14.4 0.9 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Cysteine-rich domain Ras PF00071.17 EKE38670.1 - 3.2e-31 107.9 0.0 3.9e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38670.1 - 3.6e-12 46.8 0.0 5.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EKE38670.1 - 0.00051 19.5 0.1 0.047 13.1 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EKE38670.1 - 0.00084 19.2 0.0 0.0046 16.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EKE38670.1 - 0.0087 15.3 0.0 0.019 14.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.1 EKE38670.1 - 0.0094 15.8 0.3 0.042 13.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.5 EKE38670.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3721 PF12518.3 EKE38670.1 - 0.016 14.8 0.3 0.035 13.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function FeoB_N PF02421.13 EKE38670.1 - 0.031 13.5 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EKE38670.1 - 0.049 13.3 0.1 0.093 12.4 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase Guanylate_kin PF00625.16 EKE38671.1 - 3.2e-56 189.6 1.3 3.6e-56 189.5 0.9 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EKE38671.1 - 2.6e-06 27.7 0.0 4.7e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EKE38671.1 - 9.2e-06 25.9 0.0 1.4e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EKE38671.1 - 1.7e-05 25.6 0.0 2.5e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKE38671.1 - 6.1e-05 22.9 0.1 0.00072 19.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE38671.1 - 0.00022 21.0 0.2 0.00032 20.4 0.2 1.4 1 1 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EKE38671.1 - 0.00031 20.8 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EKE38671.1 - 0.00043 20.4 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKE38671.1 - 0.00066 18.8 0.1 0.0016 17.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE38671.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EKE38671.1 - 0.0028 17.8 0.6 0.042 14.0 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EKE38671.1 - 0.003 17.0 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CoaE PF01121.15 EKE38671.1 - 0.004 16.5 0.5 0.023 14.0 0.4 1.9 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_14 PF13173.1 EKE38671.1 - 0.0042 16.9 0.0 0.0076 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EKE38671.1 - 0.0073 16.8 0.1 0.014 15.8 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein AAA_15 PF13175.1 EKE38671.1 - 0.0098 14.9 0.3 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EKE38671.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.5 EKE38671.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.1 EKE38671.1 - 0.018 14.9 0.0 0.18 11.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 EKE38671.1 - 0.023 14.1 0.2 0.058 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EKE38671.1 - 0.023 15.0 2.6 0.24 11.7 1.8 2.2 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EKE38671.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 NTPase UPF0079 PF02367.12 EKE38671.1 - 0.026 14.1 0.3 0.055 13.0 0.0 1.8 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 EKE38671.1 - 0.035 12.8 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EKE38671.1 - 0.035 13.6 0.9 0.65 9.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_PrkA PF08298.6 EKE38671.1 - 0.044 12.4 0.4 0.12 11.0 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain AAA_25 PF13481.1 EKE38671.1 - 0.047 13.0 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EKE38671.1 - 0.049 13.2 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.12 EKE38671.1 - 0.049 13.0 0.5 0.23 10.8 0.0 2.0 1 1 1 2 2 2 0 Thymidylate kinase cobW PF02492.14 EKE38671.1 - 0.056 12.8 0.4 0.19 11.1 0.0 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_tranf_2_2 PF10111.4 EKE38671.1 - 0.057 12.5 0.1 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 AAA_5 PF07728.9 EKE38671.1 - 0.059 13.1 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) PRK PF00485.13 EKE38671.1 - 0.06 12.9 0.1 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EKE38671.1 - 0.092 11.8 0.3 0.24 10.4 0.2 1.8 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.24 EKE38672.1 - 6.1e-41 139.7 0.0 1.3e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EKE38672.1 - 2.7e-25 88.0 0.0 9.1e-25 86.3 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EKE38672.1 - 1.3e-16 60.1 4.8 1.3e-16 60.1 3.3 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TIP49 PF06068.8 EKE38672.1 - 5.8e-06 25.2 0.3 0.00028 19.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EKE38672.1 - 1.6e-05 25.7 0.4 9.1e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKE38672.1 - 1.7e-05 24.9 0.0 0.0005 20.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EKE38672.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EKE38672.1 - 4.7e-05 22.5 0.0 8.2e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EKE38672.1 - 0.00013 21.4 0.2 0.1 12.0 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 EKE38672.1 - 0.00039 20.3 0.0 0.00094 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EKE38672.1 - 0.00045 20.5 2.2 0.018 15.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EKE38672.1 - 0.00046 19.1 0.0 0.0008 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EKE38672.1 - 0.0005 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKE38672.1 - 0.0011 18.7 0.0 0.0067 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EKE38672.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKE38672.1 - 0.002 18.3 0.0 0.0051 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EKE38672.1 - 0.0038 17.2 0.0 0.026 14.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EKE38672.1 - 0.018 14.2 0.1 0.05 12.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EKE38672.1 - 0.023 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EKE38672.1 - 0.029 14.3 0.1 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.1 EKE38672.1 - 0.034 13.9 6.9 0.048 13.4 1.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_24 PF13479.1 EKE38672.1 - 0.035 13.6 0.2 0.96 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EKE38672.1 - 0.036 13.1 0.4 0.44 9.6 0.0 2.5 2 1 1 3 3 3 0 Zeta toxin TPR_1 PF00515.23 EKE38672.1 - 0.044 13.4 0.7 0.044 13.4 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_19 PF13245.1 EKE38672.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EKE38672.1 - 0.045 13.1 0.1 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 EKE38672.1 - 0.051 12.8 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EKE38672.1 - 0.051 13.2 2.1 0.14 11.8 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 EKE38672.1 - 0.058 12.8 0.0 0.45 9.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EKE38672.1 - 0.12 12.0 0.0 2.8 7.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain TPR_2 PF07719.12 EKE38672.1 - 0.2 11.6 4.1 0.55 10.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat STT3 PF02516.9 EKE38674.1 - 1.1e-106 357.7 40.2 1.9e-106 356.9 27.9 1.3 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 EKE38674.1 - 1.3e-05 25.1 17.7 1.3e-05 25.1 12.3 3.8 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MCM PF00493.18 EKE38675.1 - 6e-131 436.1 0.1 8.4e-131 435.6 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKE38675.1 - 4.1e-15 56.3 1.0 1.1e-14 54.9 0.1 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKE38675.1 - 2.9e-08 33.1 0.0 3.4e-06 26.3 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKE38675.1 - 0.0017 17.9 0.0 0.0061 16.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKE38675.1 - 0.0058 16.3 0.0 0.023 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EKE38675.1 - 0.0093 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF1423 PF07227.6 EKE38675.1 - 0.015 13.9 0.6 0.031 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Transp_cyt_pur PF02133.10 EKE38675.1 - 0.2 10.1 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Nol1_Nop2_Fmu PF01189.12 EKE38676.1 - 1.7e-29 103.0 0.1 3.4e-29 102.1 0.0 1.4 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 EKE38676.1 - 5.1e-05 23.3 0.1 0.0004 20.4 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EKE38676.1 - 0.0021 17.6 0.4 0.0021 17.6 0.3 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE38676.1 - 0.0033 17.4 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rep-A_N PF04057.7 EKE38676.1 - 0.56 10.0 4.8 5.1 6.9 0.0 2.7 2 1 1 3 3 3 0 Replication factor-A protein 1, N-terminal domain TPR_8 PF13181.1 EKE38677.1 - 1.4e-05 24.5 0.5 7.5e-05 22.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKE38677.1 - 5e-05 22.9 0.1 0.00022 20.9 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKE38677.1 - 0.0028 17.2 0.1 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EKE38677.1 - 0.0029 17.1 0.3 0.0076 15.8 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKE38677.1 - 0.0077 16.6 0.0 2.8 8.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKE38677.1 - 0.066 13.0 0.1 0.98 9.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fibrillarin PF01269.12 EKE38678.1 - 1.1e-102 341.8 0.0 1.3e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EKE38678.1 - 0.0081 15.6 0.1 0.022 14.2 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EKE38678.1 - 0.025 14.1 0.1 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EKE38678.1 - 0.047 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Phospholip_B PF04916.8 EKE38680.1 - 6.9e-102 341.3 13.8 9e-102 340.9 9.6 1.0 1 0 0 1 1 1 1 Phospholipase B Pkinase_Tyr PF07714.12 EKE38681.1 - 6.5e-48 163.0 0.0 1e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38681.1 - 5.5e-42 143.7 0.0 9.2e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2668 PF10873.3 EKE38681.1 - 0.0048 17.0 0.9 0.0048 17.0 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) Staphopain_pro PF14731.1 EKE38681.1 - 0.014 15.1 0.9 0.036 13.8 0.6 1.7 1 0 0 1 1 1 0 Staphopain proregion Beta-TrCP_D PF12125.3 EKE38681.1 - 0.028 13.9 0.2 0.028 13.9 0.1 2.1 2 0 0 2 2 2 0 D domain of beta-TrCP EphA2_TM PF14575.1 EKE38681.1 - 0.08 13.3 0.9 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EKE38681.1 - 0.31 10.7 1.8 0.85 9.3 1.2 1.7 1 0 0 1 1 1 0 Syndecan domain hEGF PF12661.2 EKE38681.1 - 1.8 8.8 14.0 1.2 9.3 1.3 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF Epsilon_antitox PF08998.6 EKE38682.1 - 0.087 12.8 0.1 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Bacterial epsilon antitoxin DSPc PF00782.15 EKE38684.1 - 2.8e-29 101.3 2.7 7.8e-29 99.9 0.0 2.6 2 2 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EKE38684.1 - 6.1e-05 23.1 5.2 0.00017 21.6 3.6 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EKE38684.1 - 0.0013 18.0 0.6 0.0019 17.5 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EKE38684.1 - 0.057 13.6 0.3 0.97 9.6 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family Toxin_10 PF05431.6 EKE38684.1 - 0.4 10.3 5.4 1.3 8.6 3.7 1.8 1 1 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Ras PF00071.17 EKE38686.1 - 1.2e-06 28.0 0.7 1.4e-06 27.7 0.5 1.1 1 0 0 1 1 1 1 Ras family POLO_box PF00659.13 EKE38686.1 - 0.0045 16.9 0.5 0.0084 16.0 0.3 1.5 1 0 0 1 1 1 1 POLO box duplicated region AAA_31 PF13614.1 EKE38686.1 - 0.085 12.7 0.4 0.1 12.5 0.3 1.1 1 0 0 1 1 1 0 AAA domain WH1 PF00568.18 EKE38686.1 - 0.11 12.1 2.5 0.13 11.9 1.4 1.4 1 1 0 1 1 1 0 WH1 domain MFP2b PF12150.3 EKE38686.1 - 0.12 11.0 0.8 0.14 10.8 0.5 1.0 1 0 0 1 1 1 0 Cytosolic motility protein Glycohydro_20b2 PF14845.1 EKE38688.1 - 0.6 10.7 3.3 45 4.7 0.0 3.0 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like Ras PF00071.17 EKE38689.1 - 2.1e-18 66.2 0.0 4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38689.1 - 1.4e-08 35.2 0.0 6e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Salp15 PF12115.3 EKE38689.1 - 0.66 10.2 5.8 0.57 10.4 2.6 1.8 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Snf7 PF03357.16 EKE38690.1 - 3.9e-25 88.2 15.8 4.5e-25 87.9 11.0 1.0 1 0 0 1 1 1 1 Snf7 YodL PF14191.1 EKE38690.1 - 0.045 14.2 2.5 0.079 13.4 1.8 1.4 1 0 0 1 1 1 0 YodL-like CAMSAP_CKK PF08683.6 EKE38690.1 - 0.077 12.6 3.9 0.17 11.5 2.5 1.6 1 1 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated COG5 PF10392.4 EKE38690.1 - 0.3 11.0 9.6 31 4.5 5.9 2.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 MerR-DNA-bind PF09278.6 EKE38690.1 - 0.45 10.9 0.1 0.45 10.9 0.1 2.8 3 1 0 3 3 3 0 MerR, DNA binding Streptin-Immun PF11083.3 EKE38691.1 - 0.99 9.4 6.4 0.19 11.7 1.4 2.0 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein Reo_sigmaC PF04582.7 EKE38692.1 - 0.015 14.4 0.0 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2051 PF09738.4 EKE38692.1 - 0.081 12.2 0.2 0.1 11.8 0.2 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF972 PF06156.8 EKE38692.1 - 0.11 12.8 0.2 0.11 12.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 EKE38692.1 - 0.57 10.5 4.7 0.49 10.7 1.9 1.7 1 1 0 1 1 1 0 Snapin/Pallidin Mod_r PF07200.8 EKE38692.1 - 0.87 9.4 5.8 5.7 6.8 0.8 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein EnY2 PF10163.4 EKE38693.1 - 0.9 9.5 5.0 0.69 9.8 1.9 2.0 2 0 0 2 2 2 0 Transcription factor e(y)2 SNARE_assoc PF09335.6 EKE38694.1 - 8e-06 26.0 3.4 9.2e-06 25.8 0.4 2.5 1 1 1 2 2 2 1 SNARE associated Golgi protein Peptidase_A22B PF04258.8 EKE38696.1 - 3.2e-65 220.5 17.6 3.9e-65 220.2 12.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PIG-P PF08510.7 EKE38696.1 - 0.34 10.5 12.3 5.5 6.6 0.0 3.5 3 0 0 3 3 3 0 PIG-P Metallophos PF00149.23 EKE38697.1 - 6.3e-37 126.9 0.1 7.9e-37 126.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S74 PF13884.1 EKE38698.1 - 2.7e-14 53.0 0.0 5.5e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase Fibrillarin PF01269.12 EKE38698.1 - 0.012 14.4 0.1 0.62 8.9 0.0 2.2 2 0 0 2 2 2 0 Fibrillarin TetR_C_2 PF08361.6 EKE38699.1 - 0.073 12.9 0.3 0.15 12.0 0.2 1.6 1 1 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region YpjP PF14005.1 EKE38699.1 - 2.8 7.7 17.9 2.3 7.9 1.1 3.1 1 1 2 3 3 3 0 YpjP-like protein SapB_2 PF03489.12 EKE38700.1 - 1.4e-07 31.4 1.4 2.5e-07 30.5 0.4 1.8 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EKE38700.1 - 3.6e-05 23.4 1.6 3.6e-05 23.4 1.1 2.8 3 2 0 3 3 3 1 Saposin-like type B, region 1 Antimicrobial19 PF08225.6 EKE38700.1 - 0.044 13.1 0.6 0.22 10.9 0.1 2.1 2 0 0 2 2 2 0 Pseudin antimicrobial peptide DUF2384 PF09722.5 EKE38700.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) LIM PF00412.17 EKE38702.1 - 8.7e-10 38.5 10.1 8.7e-10 38.5 7.0 2.0 2 1 0 2 2 2 1 LIM domain zf-ribbon_3 PF13248.1 EKE38702.1 - 1.6e-06 27.1 22.2 3.7e-05 22.7 6.2 3.6 3 1 0 3 3 3 2 zinc-ribbon domain RRN7 PF11781.3 EKE38702.1 - 7.7e-05 22.1 12.6 0.013 14.9 0.3 4.2 3 2 0 3 3 3 2 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EKE38702.1 - 0.00069 19.3 19.4 0.034 13.9 9.4 3.3 1 1 1 2 2 2 1 Double zinc ribbon zf-dskA_traR PF01258.12 EKE38702.1 - 0.0033 17.1 8.9 0.18 11.5 0.3 4.2 4 0 0 4 4 4 1 Prokaryotic dksA/traR C4-type zinc finger Cytochrome_C7 PF14522.1 EKE38702.1 - 0.0033 17.0 8.0 0.0033 17.0 5.6 2.8 2 1 0 2 2 2 1 Cytochrome c7 zinc_ribbon_2 PF13240.1 EKE38702.1 - 0.0046 16.4 10.9 0.0046 16.4 7.6 4.6 4 1 0 4 4 4 1 zinc-ribbon domain Cytochrom_c3_2 PF14537.1 EKE38702.1 - 0.01 16.1 15.3 0.08 13.2 7.0 3.0 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C554 PF13435.1 EKE38702.1 - 0.043 13.8 1.8 0.043 13.8 1.2 2.9 2 2 1 3 3 3 0 Cytochrome c554 and c-prime zinc-ribbons_6 PF07191.7 EKE38702.1 - 0.1 12.3 11.8 3.3 7.5 0.2 2.8 2 1 0 2 2 2 0 zinc-ribbons Rep_fac-A_C PF08646.5 EKE38702.1 - 0.13 11.9 2.0 0.38 10.4 1.4 1.8 1 1 0 1 1 1 0 Replication factor-A C terminal domain DUF3279 PF11682.3 EKE38702.1 - 0.18 11.4 10.2 0.19 11.2 0.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3279) Cytochrom_CIII PF02085.11 EKE38702.1 - 0.56 10.3 12.1 0.64 10.1 5.3 2.6 2 1 0 2 2 2 0 Class III cytochrome C family Paired_CXXCH_1 PF09699.5 EKE38702.1 - 0.66 9.5 18.1 0.21 11.0 4.1 3.8 3 2 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF1364 PF07102.7 EKE38702.1 - 1.4 8.8 4.8 7.1 6.5 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) Zn-ribbon_8 PF09723.5 EKE38702.1 - 1.6 8.7 24.0 2.1 8.3 3.5 4.2 4 0 0 4 4 4 0 Zinc ribbon domain Metallothio_Pro PF02069.11 EKE38702.1 - 5.8 6.8 11.7 1.4 8.8 2.2 2.9 2 1 1 3 3 3 0 Prokaryotic metallothionein Zn_Tnp_IS1595 PF12760.2 EKE38702.1 - 5.9 6.7 22.0 0.19 11.5 3.5 4.0 3 1 0 3 3 3 0 Transposase zinc-ribbon domain UPF0547 PF10571.4 EKE38702.1 - 8.5 6.1 14.9 8.5 6.1 0.5 3.6 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 TP6A_N PF04406.9 EKE38703.1 - 2.5e-19 68.6 0.7 5.5e-19 67.6 0.5 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EKE38703.1 - 1.9e-05 24.5 0.0 5.1e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) Arf PF00025.16 EKE38704.1 - 4.8e-44 149.6 0.0 5.3e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EKE38704.1 - 8.5e-13 48.0 0.0 1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38704.1 - 1.2e-07 32.2 0.0 1.7e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EKE38704.1 - 5.3e-06 25.7 0.0 6.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EKE38704.1 - 1.5e-05 23.9 3.2 0.00048 18.9 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EKE38704.1 - 9.1e-05 21.6 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE38704.1 - 0.0008 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE38704.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKE38704.1 - 0.14 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EKE38706.1 - 9.2e-52 175.7 0.0 1.6e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38706.1 - 2.6e-51 174.1 0.0 3.9e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.1 EKE38706.1 - 9.9e-06 25.3 1.5 2.5e-05 23.9 1.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Tetraspannin PF00335.15 EKE38706.1 - 0.00053 19.3 3.6 0.0013 18.0 2.5 1.6 1 0 0 1 1 1 1 Tetraspanin family DUF912 PF06024.7 EKE38706.1 - 0.00069 19.6 3.0 0.00069 19.6 2.1 2.0 2 0 0 2 2 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Kdo PF06293.9 EKE38706.1 - 0.0012 17.9 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Tmemb_9 PF05434.6 EKE38706.1 - 0.0039 16.9 2.7 0.0083 15.8 1.9 1.5 1 0 0 1 1 1 1 TMEM9 Rifin_STEVOR PF02009.11 EKE38706.1 - 0.0044 16.7 3.8 0.014 15.0 2.6 1.8 1 0 0 1 1 1 1 Rifin/stevor family MRAP PF15183.1 EKE38706.1 - 0.016 14.8 0.5 0.064 12.8 0.4 2.0 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Shisa PF13908.1 EKE38706.1 - 0.048 13.8 0.3 0.048 13.8 0.2 2.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator EVI2A PF05399.6 EKE38706.1 - 0.16 11.2 3.5 0.36 10.0 2.4 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) FG-GAP_2 PF14312.1 EKE38706.1 - 0.52 10.3 3.4 24 5.0 0.1 3.4 3 0 0 3 3 3 0 FG-GAP repeat ODV-E18 PF10717.4 EKE38706.1 - 0.64 9.5 6.4 2.3 7.7 4.4 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.6 EKE38706.1 - 4.1 6.8 5.6 1.8 8.0 1.9 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein Baculo_11_kDa PF06143.6 EKE38706.1 - 7.4 6.0 11.0 1.9 7.8 4.9 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family OAD_gamma PF04277.8 EKE38706.1 - 7.9 6.9 8.0 40 4.6 3.5 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain VHS PF00790.14 EKE38707.1 - 0.00043 19.9 0.1 0.014 15.0 0.0 2.7 2 1 0 2 2 2 1 VHS domain Mito_fiss_reg PF05308.6 EKE38707.1 - 0.0068 15.7 3.8 0.011 15.1 2.7 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator NRDE-2 PF08424.5 EKE38707.1 - 0.036 12.9 0.1 0.052 12.4 0.1 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference 4HB_MCP_1 PF12729.2 EKE38707.1 - 0.063 12.6 3.4 0.13 11.5 2.2 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Mem_trans PF03547.13 EKE38708.1 - 2.1e-44 151.4 11.4 2.4e-44 151.2 7.9 1.0 1 0 0 1 1 1 1 Membrane transport protein DUF2681 PF10883.3 EKE38708.1 - 0.52 10.5 6.5 0.84 9.8 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) TT_ORF1 PF02956.9 EKE38708.1 - 0.96 7.8 8.1 1.3 7.3 5.6 1.1 1 0 0 1 1 1 0 TT viral orf 1 Carb_kinase PF01256.12 EKE38709.1 - 9.4e-55 185.5 0.0 1.1e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EKE38709.1 - 0.081 12.0 0.2 0.12 11.4 0.1 1.4 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family RRM_1 PF00076.17 EKE38710.1 - 1.4e-17 63.0 0.2 2.6e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE38710.1 - 6.9e-12 45.1 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE38710.1 - 5.7e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 EKE38710.1 - 0.03 14.1 0.1 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Fer4 PF00037.22 EKE38711.1 - 3.4e-13 48.5 18.2 8.3e-07 28.3 1.4 2.6 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EKE38711.1 - 1.9e-09 37.7 14.2 4.7e-09 36.4 9.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE38711.1 - 2.8e-09 36.6 12.3 5.6e-09 35.6 8.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE38711.1 - 1.6e-08 34.0 17.3 0.00012 21.8 3.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EKE38711.1 - 3.7e-08 33.5 13.5 3.7e-08 33.5 9.4 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EKE38711.1 - 6.5e-07 29.1 15.2 1.6e-06 27.8 10.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE38711.1 - 7.4e-07 28.7 22.0 0.0026 17.5 5.6 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 EKE38711.1 - 1.4e-06 28.9 10.8 0.0053 17.4 2.1 2.7 2 1 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EKE38711.1 - 1.6e-06 28.0 28.9 5.7e-05 23.0 11.0 2.3 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 EKE38711.1 - 2.2e-06 27.5 20.9 0.00099 19.2 2.0 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EKE38711.1 - 8.3e-05 22.8 13.6 0.011 16.1 2.4 2.6 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EKE38711.1 - 0.0004 20.7 16.6 0.018 15.4 3.1 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 EKE38711.1 - 0.0089 16.5 26.9 0.028 14.9 3.1 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain IBN_N PF03810.14 EKE38711.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Importin-beta N-terminal domain Fer4_13 PF13370.1 EKE38711.1 - 0.12 12.8 14.7 1.9 8.9 0.8 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 EKE38711.1 - 0.36 11.4 19.4 0.38 11.3 1.1 3.3 1 1 1 2 2 2 0 4Fe-4S single cluster domain Pkinase PF00069.20 EKE38712.1 - 3e-20 72.4 1.0 3.7e-20 72.1 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38712.1 - 8.6e-11 41.3 0.4 1.1e-10 41.0 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38713.1 - 1.4e-12 47.3 0.0 1.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FMN_dh PF01070.13 EKE38714.1 - 5.7e-23 81.3 0.1 1.2e-17 63.7 0.1 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EKE38714.1 - 0.00016 20.7 0.2 0.0021 17.0 0.0 2.6 2 2 2 4 4 4 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 EKE38714.1 - 0.00031 19.7 0.1 0.00048 19.1 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EKE38714.1 - 0.02 13.7 0.0 0.37 9.6 0.0 2.4 2 0 0 2 2 2 0 Conserved region in glutamate synthase GutM PF06923.6 EKE38715.1 - 0.032 13.8 0.3 0.47 10.1 0.0 2.4 2 0 0 2 2 2 0 Glucitol operon activator protein (GutM) DUF2935 PF11155.3 EKE38715.1 - 0.068 13.2 1.2 0.38 10.8 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF3169 PF11368.3 EKE38718.1 - 0.036 13.2 0.6 0.036 13.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2636 PF11120.3 EKE38718.1 - 0.15 11.5 0.6 2.4 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) LRR_5 PF13306.1 EKE38719.1 - 5.7e-34 116.6 12.8 5.7e-34 116.6 8.9 1.9 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38719.1 - 8.8e-19 67.0 15.0 6.5e-07 29.0 0.6 3.4 1 1 3 4 4 4 4 Leucine rich repeat F-box-like PF12937.2 EKE38719.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like zf-Tim10_DDP PF02953.10 EKE38719.1 - 1 8.6 4.7 1.1 8.6 0.0 3.0 3 0 0 3 3 3 0 Tim10/DDP family zinc finger Pox_A22 PF04848.8 EKE38721.1 - 0.058 13.2 0.8 0.1 12.4 0.5 1.5 1 0 0 1 1 1 0 Poxvirus A22 protein IBR PF01485.16 EKE38722.1 - 6.2e-13 48.4 50.4 2.7e-11 43.1 3.8 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EKE38722.1 - 6.6e-05 22.4 9.3 6.6e-05 22.4 6.5 5.2 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE38722.1 - 0.00055 19.7 7.5 0.00055 19.7 5.2 4.0 2 1 1 3 3 3 1 Ring finger domain zf-NADH-PPase PF09297.6 EKE38722.1 - 0.0084 15.6 1.7 0.0084 15.6 1.2 5.3 5 0 0 5 5 5 1 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_2 PF13923.1 EKE38722.1 - 0.011 15.7 9.9 0.011 15.7 6.9 5.2 3 3 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 EKE38722.1 - 0.041 13.3 1.1 0.041 13.3 0.8 5.5 5 1 0 5 5 5 0 zinc-ribbon domain DUF1241 PF06840.6 EKE38723.1 - 0.0032 16.7 0.4 0.0048 16.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DUF2031 PF09592.5 EKE38723.1 - 0.0081 15.3 2.7 0.0081 15.3 1.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2031) TMPIT PF07851.8 EKE38723.1 - 0.012 14.6 0.2 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Vps53_N PF04100.7 EKE38723.1 - 0.013 14.3 0.4 0.013 14.3 0.3 1.5 2 0 0 2 2 2 0 Vps53-like, N-terminal DUF1664 PF07889.7 EKE38723.1 - 0.018 14.8 3.3 0.14 11.9 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CtIP_N PF10482.4 EKE38723.1 - 0.029 14.1 1.0 0.052 13.3 0.7 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF4164 PF13747.1 EKE38723.1 - 0.077 13.1 1.3 0.28 11.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF4298 PF14131.1 EKE38723.1 - 0.2 11.5 1.9 1.7 8.5 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) Suf PF05843.9 EKE38723.1 - 0.25 11.0 9.3 0.76 9.4 6.1 1.7 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Nsp1_C PF05064.8 EKE38723.1 - 0.69 9.5 4.5 0.17 11.5 0.5 1.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region ATG16 PF08614.6 EKE38723.1 - 2.9 7.6 7.3 8.7 6.1 3.2 2.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ACP53EA PF06313.6 EKE38724.1 - 0.082 12.8 1.8 0.26 11.2 1.2 1.8 1 0 0 1 1 1 0 Drosophila ACP53EA protein AMP-binding PF00501.23 EKE38726.1 - 4.3e-83 279.0 0.0 6.5e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peripla_BP_3 PF13377.1 EKE38726.1 - 0.24 11.4 0.0 1 9.3 0.0 1.8 1 1 0 1 1 1 0 Periplasmic binding protein-like domain Pkinase PF00069.20 EKE38727.1 - 6.4e-49 166.4 0.0 1.2e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38727.1 - 1.9e-47 161.5 0.0 3.7e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE38727.1 - 0.0018 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family VSP PF03302.8 EKE38727.1 - 0.0037 15.9 121.0 10 4.6 17.1 5.4 1 1 3 4 4 4 2 Giardia variant-specific surface protein HSP70 PF00012.15 EKE38728.1 - 2.6e-82 276.6 8.3 1.8e-81 273.8 5.8 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE38728.1 - 1.2e-10 40.5 2.5 5.4e-09 35.1 0.5 3.1 3 1 0 3 3 3 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EKE38728.1 - 0.016 14.2 0.1 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Mago_nashi PF02792.9 EKE38728.1 - 0.022 14.4 2.4 1.9 8.1 0.0 3.0 3 0 0 3 3 3 0 Mago nashi protein FtsA PF14450.1 EKE38728.1 - 0.14 12.0 4.8 25 4.7 2.6 3.3 2 1 0 2 2 2 0 Cell division protein FtsA AIG1 PF04548.11 EKE38729.1 - 7.2e-11 41.5 0.3 7.2e-11 41.5 0.2 2.2 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 EKE38729.1 - 4.7e-07 29.7 0.1 2.1e-06 27.6 0.1 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EKE38729.1 - 8.9e-07 28.1 0.4 8.9e-07 28.1 0.3 2.2 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 EKE38729.1 - 1e-06 28.0 0.0 2.9e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EKE38729.1 - 9.6e-06 24.6 0.0 1.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EKE38729.1 - 3.8e-05 22.8 0.0 0.00014 21.0 0.0 1.9 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EKE38729.1 - 0.00017 21.0 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 EKE38729.1 - 0.00019 20.9 0.1 0.00051 19.5 0.0 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EKE38729.1 - 0.00043 20.0 0.4 0.0018 17.9 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EKE38729.1 - 0.00059 19.3 0.0 0.0023 17.4 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EKE38729.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EKE38729.1 - 0.0021 18.2 0.0 0.0088 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKE38729.1 - 0.0022 18.7 3.6 0.04 14.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EKE38729.1 - 0.0031 17.8 20.6 0.0031 17.8 14.3 4.0 1 1 1 3 3 2 1 AAA domain GTP_EFTU PF00009.22 EKE38729.1 - 0.0041 16.5 0.1 0.014 14.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EKE38729.1 - 0.0074 16.7 0.0 0.036 14.5 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 EKE38729.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EKE38729.1 - 0.0075 16.1 1.7 0.018 14.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKE38729.1 - 0.011 15.5 0.0 0.035 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF1454 PF07305.7 EKE38729.1 - 0.012 14.7 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) AAA_16 PF13191.1 EKE38729.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EKE38729.1 - 0.047 13.9 0.0 0.047 13.9 0.0 2.8 3 2 0 3 3 3 0 ABC transporter DUF87 PF01935.12 EKE38729.1 - 0.073 12.8 0.1 0.073 12.8 0.0 3.6 3 1 0 3 3 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EKE38729.1 - 0.11 11.9 4.4 0.38 10.1 3.0 2.2 1 1 0 1 1 1 0 AAA-like domain AMP-binding PF00501.23 EKE38731.1 - 6.4e-74 248.8 0.0 7.6e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UPF0128 PF03673.8 EKE38731.1 - 0.00085 18.6 0.6 0.0016 17.7 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0128) CBM_20 PF00686.14 EKE38733.1 - 2.6e-15 55.7 0.9 2.6e-15 55.7 0.7 1.6 1 1 1 2 2 2 1 Starch binding domain tRNA-synt_1b PF00579.20 EKE38733.1 - 0.015 14.4 0.0 0.017 14.2 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AMP-binding PF00501.23 EKE38734.1 - 1.1e-70 238.0 0.0 1.5e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SH3_1 PF00018.23 EKE38734.1 - 0.03 13.7 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 SH3 domain SH3_2 PF07653.12 EKE38734.1 - 0.037 13.5 0.0 0.15 11.5 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain NADH_4Fe-4S PF10589.4 EKE38734.1 - 0.16 11.1 0.9 0.35 10.0 0.6 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region RasGEF PF00617.14 EKE38736.1 - 7.7e-23 81.1 6.3 1.8e-22 79.9 4.2 1.7 1 1 1 2 2 2 1 RasGEF domain YlbD_coat PF14071.1 EKE38736.1 - 4.3 7.4 10.4 2.4 8.2 0.0 3.3 4 0 0 4 4 4 0 Putative coat protein Glycos_transf_2 PF00535.21 EKE38737.1 - 1.8e-29 102.6 0.0 2.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.9 EKE38737.1 - 2.4e-23 82.3 7.9 2.4e-23 82.3 5.5 1.6 2 0 0 2 2 2 1 GtrA-like protein Glyco_tranf_2_2 PF10111.4 EKE38737.1 - 8.5e-09 34.8 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EKE38737.1 - 3.2e-08 33.6 0.0 4.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Response_reg PF00072.19 EKE38737.1 - 0.061 13.3 0.3 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Response regulator receiver domain CAP59_mtransfer PF11735.3 EKE38737.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 RabGAP-TBC PF00566.13 EKE38738.1 - 9e-06 25.3 3.2 9e-06 25.3 2.2 3.1 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 EKE38738.1 - 1e-05 25.8 0.0 3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Helicase_C_2 PF13307.1 EKE38739.1 - 7.2e-55 185.4 0.3 2e-54 184.0 0.1 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EKE38739.1 - 3.1e-26 91.8 0.7 7.5e-26 90.5 0.5 1.7 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 EKE38739.1 - 1.8e-06 27.5 0.2 0.00046 19.7 0.0 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EKE38739.1 - 8.9e-05 22.3 10.6 0.00018 21.3 0.0 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EKE38739.1 - 0.0037 16.9 0.1 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EKE38739.1 - 0.045 13.8 0.3 13 5.8 0.1 3.2 2 0 0 2 2 2 0 AAA domain RPN7 PF10602.4 EKE38740.1 - 1.5e-15 57.0 0.0 3.8e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EKE38740.1 - 2.9e-10 40.4 0.3 2.9e-10 40.4 0.2 1.6 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EKE38740.1 - 0.00012 21.8 0.2 0.0004 20.1 0.1 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EKE38740.1 - 0.0024 17.4 0.2 0.0044 16.6 0.0 1.6 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DNA_topoisoIV PF00521.15 EKE38740.1 - 0.014 14.2 0.7 0.022 13.5 0.5 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Myb_DNA-bind_3 PF12776.2 EKE38741.1 - 0.31 11.7 7.3 4.5 7.9 0.4 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PP2C_2 PF13672.1 EKE38743.1 - 3.2e-11 43.0 0.0 4.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE38743.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Hus1 PF04005.7 EKE38744.1 - 1.5e-27 96.3 0.5 1.9e-27 96.0 0.4 1.0 1 0 0 1 1 1 1 Hus1-like protein Ras PF00071.17 EKE38745.1 - 4.3e-13 48.9 0.1 8.4e-13 48.0 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKE38745.1 - 0.00035 21.0 0.0 0.00067 20.1 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein RNA_pol_L_2 PF13656.1 EKE38745.1 - 0.013 14.8 0.1 0.19 11.1 0.0 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Nucleoside_tran PF01733.13 EKE38746.1 - 2.9e-14 52.9 5.8 2.9e-14 52.9 4.0 3.1 1 1 1 2 2 2 1 Nucleoside transporter DUF1510 PF07423.6 EKE38746.1 - 0.0069 15.7 2.5 0.011 15.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Peptidase_C54 PF03416.14 EKE38747.1 - 5.3e-33 114.3 0.3 5.1e-31 107.8 0.2 2.4 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EKE38747.1 - 0.026 13.6 0.0 0.44 9.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C78 DUF1569 PF07606.6 EKE38748.1 - 0.13 12.1 0.1 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Erv26 PF04148.8 EKE38749.1 - 1e-15 57.6 17.0 9.1e-15 54.5 11.8 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 TLD PF07534.11 EKE38750.1 - 3.3e-06 27.1 0.5 5.3e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 TLD Spc7 PF08317.6 EKE38750.1 - 0.014 14.1 1.2 0.019 13.6 0.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.1 EKE38750.1 - 0.064 13.2 1.3 0.091 12.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) COMP PF11598.3 EKE38750.1 - 0.096 12.7 1.0 0.18 11.9 0.7 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.5 EKE38750.1 - 0.41 10.7 2.2 0.59 10.2 0.2 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EKE38750.1 - 0.58 9.9 4.0 0.9 9.3 2.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SNF2_N PF00176.18 EKE38751.1 - 7.4e-71 238.3 1.6 1.7e-70 237.2 1.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE38751.1 - 1.7e-16 59.8 0.0 4.4e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 EKE38751.1 - 6.9e-14 51.2 5.3 3.9e-08 32.8 0.9 3.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Rad9 PF04139.8 EKE38752.1 - 0.00031 19.9 3.1 0.045 12.8 0.3 2.3 1 1 1 2 2 2 2 Rad9 PCNA_N PF00705.13 EKE38752.1 - 0.043 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain DUF4369 PF14289.1 EKE38752.1 - 1.2 9.1 5.5 2.4 8.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4369) LRR_5 PF13306.1 EKE38753.1 - 5.2e-68 226.6 54.6 5.2e-26 90.8 9.7 3.5 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38753.1 - 1.6e-26 91.8 30.4 3e-06 26.8 0.5 6.4 1 1 5 6 6 6 6 Leucine rich repeat DUF1484 PF07363.6 EKE38753.1 - 0.0029 17.9 2.1 0.59 10.4 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1484) Oscp1 PF10188.4 EKE38753.1 - 0.054 13.3 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Organic solute transport protein 1 FNIP PF05725.7 EKE38753.1 - 1.5 8.8 23.9 6.4 6.8 0.0 7.0 3 2 2 5 5 5 0 FNIP Repeat TBPIP PF07106.8 EKE38754.1 - 5e-36 123.7 22.0 6.2e-36 123.4 15.2 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1192 PF06698.6 EKE38754.1 - 0.005 16.6 3.0 0.011 15.5 1.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Mnd1 PF03962.10 EKE38754.1 - 0.0078 15.8 18.9 0.013 15.1 13.1 1.4 1 1 0 1 1 1 1 Mnd1 family Syntaxin-6_N PF09177.6 EKE38754.1 - 0.78 10.1 10.7 5.6 7.4 5.9 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FRG1 PF06229.7 EKE38754.1 - 1.6 8.1 8.6 2.7 7.4 6.0 1.3 1 0 0 1 1 1 0 FRG1-like family DUF489 PF04356.7 EKE38754.1 - 1.6 8.2 5.8 2.4 7.6 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF489) FlaC_arch PF05377.6 EKE38754.1 - 1.7 8.6 16.1 3.1 7.7 3.3 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 EKE38754.1 - 2.1 8.8 7.9 10 6.6 1.7 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EKE38754.1 - 3.6 7.1 18.2 7.1 6.1 12.6 1.5 1 1 0 1 1 1 0 IncA protein FKBP_N PF01346.13 EKE38754.1 - 4.8 7.2 10.5 16 5.5 7.3 1.9 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TAP42 PF04177.7 EKE38755.1 - 1.3e-44 152.5 24.8 1.6e-44 152.2 17.2 1.1 1 0 0 1 1 1 1 TAP42-like family IlvC PF01450.14 EKE38755.1 - 0.1 12.5 0.3 0.1 12.5 0.2 2.3 3 1 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain YflT PF11181.3 EKE38755.1 - 0.14 12.2 0.3 0.14 12.2 0.2 2.7 3 0 0 3 3 3 0 Heat induced stress protein YflT PFK PF00365.15 EKE38756.1 - 3.8e-25 88.4 0.3 6.3e-25 87.6 0.2 1.3 1 0 0 1 1 1 1 Phosphofructokinase Peptidase_S10 PF00450.17 EKE38756.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase Lipoprotein_9 PF03180.9 EKE38756.1 - 0.029 13.2 0.0 0.075 11.9 0.0 1.6 1 0 0 1 1 1 0 NLPA lipoprotein PNP_UDP_1 PF01048.15 EKE38757.1 - 2.4e-36 124.8 0.0 2.8e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.6 EKE38757.1 - 0.16 10.8 0.1 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) RhoGAP PF00620.22 EKE38759.1 - 2.7e-28 98.5 0.0 6.6e-28 97.2 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain Phage_GPO PF05929.6 EKE38759.1 - 0.12 11.5 0.1 0.38 9.9 0.1 1.8 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PI3Ka PF00613.15 EKE38760.1 - 9.6e-05 21.6 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HSP70 PF00012.15 EKE38762.1 - 2e-102 343.0 5.9 2.3e-102 342.9 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF3153 PF11353.3 EKE38762.1 - 0.096 12.1 0.0 0.32 10.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) DUF2203 PF09969.4 EKE38762.1 - 0.14 12.4 4.1 0.17 12.0 2.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HSP70 PF00012.15 EKE38763.1 - 1.2e-89 300.9 2.2 1.4e-89 300.6 1.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE38763.1 - 1.9e-07 30.0 0.8 0.0011 17.6 0.1 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF1413 PF07205.6 EKE38763.1 - 0.13 11.8 0.8 0.3 10.6 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) SKIP_SNW PF02731.10 EKE38764.1 - 1.3e-50 170.8 9.9 1.3e-50 170.8 6.9 2.1 1 1 1 2 2 2 1 SKIP/SNW domain Asp-B-Hydro_N PF05279.6 EKE38764.1 - 0.21 11.4 15.0 0.34 10.7 10.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Vfa1 PF08432.5 EKE38764.1 - 0.54 10.2 15.6 0.92 9.5 10.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1090 PF06476.7 EKE38764.1 - 2 8.0 20.0 2.3 7.8 12.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) PP2C_C PF07830.8 EKE38764.1 - 2.2 8.4 5.0 8.4 6.5 3.4 2.0 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain IncA PF04156.9 EKE38764.1 - 9.5 5.7 9.1 14 5.2 6.3 1.3 1 0 0 1 1 1 0 IncA protein UCH PF00443.24 EKE38765.1 - 9.1e-48 162.6 9.0 9.1e-48 162.6 6.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE38765.1 - 1.7e-20 73.6 1.2 1.7e-20 73.6 0.9 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TruD PF01142.13 EKE38766.1 - 1.1e-62 211.8 0.5 8.4e-62 208.9 0.0 2.4 2 1 1 3 3 3 1 tRNA pseudouridine synthase D (TruD) DHOase PF12890.2 EKE38766.1 - 0.0061 16.2 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 1 Dihydro-orotase-like GOLD_2 PF13897.1 EKE38766.1 - 2.1 8.5 6.6 2.9 8.1 1.6 2.5 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Suf PF05843.9 EKE38767.1 - 0.027 14.2 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Sigma70_ner PF04546.8 EKE38769.1 - 0.04 13.5 3.3 0.05 13.2 2.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PRA1 PF03208.14 EKE38770.1 - 2.9e-05 23.4 1.7 4e-05 23.0 1.2 1.1 1 0 0 1 1 1 1 PRA1 family protein Protocadherin PF08374.6 EKE38770.1 - 0.0047 16.5 0.5 0.0097 15.5 0.4 1.4 1 0 0 1 1 1 1 Protocadherin Ctr PF04145.10 EKE38770.1 - 0.019 14.9 0.4 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Ctr copper transporter family BLVR PF06375.6 EKE38770.1 - 0.086 12.6 8.4 0.13 12.0 5.8 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 EKE38770.1 - 0.092 12.2 15.0 0.12 11.8 10.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EKE38770.1 - 0.17 11.9 20.3 0.26 11.3 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) OAD_gamma PF04277.8 EKE38770.1 - 0.26 11.7 2.7 0.26 11.6 0.7 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Gcd10p PF04189.8 EKE38770.1 - 0.85 8.6 6.7 3.5 6.6 1.1 2.1 2 0 0 2 2 2 0 Gcd10p family DUF788 PF05620.6 EKE38770.1 - 7.5 6.3 7.4 2.5 7.9 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF788) Profilin PF00235.14 EKE38771.1 - 1.8e-08 34.5 0.0 2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Profilin DUF3883 PF13020.1 EKE38772.1 - 9.9e-20 70.0 2.8 1.1e-19 69.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) PPTA PF01239.17 EKE38773.1 - 0.00016 20.8 12.2 0.025 13.9 0.6 4.1 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat DUF1749 PF08538.5 EKE38774.1 - 3.1e-36 124.8 0.1 3.8e-36 124.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EKE38774.1 - 8.8e-13 48.6 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE38774.1 - 5.4e-07 29.3 0.0 5.8e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKE38774.1 - 4.2e-06 26.5 0.0 7.9e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EKE38774.1 - 2.8e-05 23.6 0.9 0.00077 18.9 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 EKE38774.1 - 0.00044 19.6 0.1 0.00061 19.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EKE38774.1 - 0.00046 19.8 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase DUF915 PF06028.6 EKE38774.1 - 0.03 13.4 0.1 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF4347 PF14252.1 EKE38774.1 - 0.03 13.8 0.2 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Archease PF01951.11 EKE38775.1 - 2.3e-25 89.1 1.2 2.5e-25 89.0 0.8 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Glyco_hydro_67C PF07477.7 EKE38777.1 - 0.12 11.7 0.5 0.78 9.1 0.0 2.4 2 1 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus UPF0278 PF08745.6 EKE38779.1 - 0.33 10.1 6.7 1.8 7.7 0.0 2.9 3 0 0 3 3 3 0 UPF0278 family Inositol_P PF00459.20 EKE38780.1 - 7.9e-63 212.2 0.0 1.3e-62 211.5 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Galactosyl_T PF01762.16 EKE38782.1 - 2e-16 60.1 0.3 3.1e-16 59.5 0.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase PP2C_2 PF13672.1 EKE38783.1 - 1.2e-11 44.4 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE38783.1 - 0.04 13.6 0.0 0.074 12.7 0.0 1.5 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) TIP49 PF06068.8 EKE38783.1 - 0.046 12.4 0.1 5.7 5.5 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Got1 PF04178.7 EKE38784.1 - 8.9e-10 38.7 27.3 1.2e-09 38.3 18.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family EcsB PF05975.7 EKE38784.1 - 0.099 11.0 21.3 0.12 10.8 14.8 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB PQQ_3 PF13570.1 EKE38785.1 - 0.014 15.6 0.1 6.7 7.1 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain ATP_bind_3 PF01171.15 EKE38786.1 - 9.8e-19 67.5 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EKE38786.1 - 7.4e-05 21.7 0.0 9.9e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 NAD synthase ATP_bind_4 PF01902.12 EKE38786.1 - 0.0018 17.6 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 ATP-binding region tRNA_Me_trans PF03054.11 EKE38786.1 - 0.011 14.3 0.0 0.037 12.5 0.0 1.8 1 1 0 1 1 1 0 tRNA methyl transferase DUF208 PF02677.9 EKE38786.1 - 0.012 15.4 0.1 0.77 9.5 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized BCR, COG1636 PHP PF02811.14 EKE38786.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 PHP domain zinc_ribbon_2 PF13240.1 EKE38786.1 - 0.13 11.7 0.4 0.13 11.7 0.3 1.8 2 0 0 2 2 2 0 zinc-ribbon domain ParA PF10609.4 EKE38787.1 - 4.9e-33 112.8 0.5 7.9e-33 112.1 0.3 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EKE38787.1 - 1.1e-15 57.6 0.0 1.7e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EKE38787.1 - 6.1e-10 39.2 0.0 7.4e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EKE38787.1 - 5.4e-06 25.6 4.2 2.4e-05 23.5 0.6 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EKE38787.1 - 2.3e-05 23.6 0.0 0.00013 21.1 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ Zeta_toxin PF06414.7 EKE38787.1 - 0.00032 19.8 0.1 0.11 11.5 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin AAA_26 PF13500.1 EKE38787.1 - 0.00041 20.0 0.5 0.065 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKE38787.1 - 0.00066 19.6 0.3 0.0028 17.5 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EKE38787.1 - 0.0024 16.6 0.3 0.0037 16.0 0.2 1.2 1 0 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 EKE38787.1 - 0.0032 17.1 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase IstB_IS21 PF01695.12 EKE38787.1 - 0.0038 16.6 0.0 0.03 13.7 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EKE38787.1 - 0.0053 16.1 1.5 0.008 15.5 1.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE38787.1 - 0.0065 16.7 0.1 0.017 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE38787.1 - 0.007 17.1 0.2 0.019 15.7 0.1 1.7 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 EKE38787.1 - 0.01 15.0 0.1 0.022 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EKE38787.1 - 0.012 15.8 0.7 0.18 12.0 0.0 2.5 3 0 0 3 3 2 0 RNA helicase DZR PF12773.2 EKE38787.1 - 0.018 14.8 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon NB-ARC PF00931.17 EKE38787.1 - 0.019 13.8 0.4 0.03 13.2 0.3 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 EKE38787.1 - 0.023 14.4 0.7 1.3 8.8 0.3 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EKE38787.1 - 0.048 13.2 0.2 0.097 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EKE38787.1 - 0.051 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EKE38787.1 - 0.057 12.8 0.6 0.16 11.3 0.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain YhjQ PF06564.7 EKE38787.1 - 0.094 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 YhjQ protein AAA_22 PF13401.1 EKE38787.1 - 0.099 12.7 0.1 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 EKE38787.1 - 0.1 11.7 0.1 0.23 10.6 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family zf-RING_3 PF14369.1 EKE38787.1 - 0.13 12.2 0.9 0.29 11.1 0.6 1.5 1 0 0 1 1 1 0 zinc-finger ABC_tran PF00005.22 EKE38787.1 - 0.15 12.3 0.1 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EKE38787.1 - 0.16 11.9 0.3 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EKE38787.1 - 0.16 11.3 0.3 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EKE38787.1 - 0.16 12.2 0.5 0.29 11.4 0.3 1.3 1 1 0 1 1 1 0 AAA domain SMK-1 PF04802.10 EKE38788.1 - 7.1e-10 38.7 6.6 7.1e-10 38.7 4.6 3.4 4 0 0 4 4 4 2 Component of IIS longevity pathway SMK-1 YmgB PF10798.3 EKE38788.1 - 4.2 7.2 8.3 37 4.2 0.3 3.9 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR Pkinase_Tyr PF07714.12 EKE38789.1 - 2e-32 112.2 0.0 2.5e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38789.1 - 7.6e-30 103.9 0.0 9.5e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M64 PF09471.5 EKE38789.1 - 0.0023 17.6 0.0 0.0048 16.5 0.0 1.3 1 1 0 1 1 1 1 IgA Peptidase M64 Metallophos PF00149.23 EKE38790.1 - 1.4e-24 86.5 0.0 2.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EKE38790.1 - 2e-18 65.8 7.8 2.8e-13 49.3 1.5 2.7 2 1 1 3 3 2 2 TPR repeat TPR_1 PF00515.23 EKE38790.1 - 4.7e-12 44.9 4.9 7.9e-06 25.2 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKE38790.1 - 3.5e-09 35.8 2.5 5.6e-06 25.8 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKE38790.1 - 2.4e-08 33.5 9.1 0.0022 18.0 0.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKE38790.1 - 1.6e-06 27.4 3.1 0.0019 17.8 0.4 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE38790.1 - 3.8e-05 23.9 0.9 0.008 16.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKE38790.1 - 4e-05 24.1 0.1 0.00036 21.1 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Metallophos_2 PF12850.2 EKE38790.1 - 4.4e-05 23.3 0.0 6.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_9 PF13371.1 EKE38790.1 - 5e-05 23.0 0.0 0.0041 16.9 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKE38790.1 - 0.0003 20.6 2.0 0.0011 18.8 0.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKE38790.1 - 0.00058 20.2 0.1 0.79 10.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EKE38790.1 - 0.0018 18.3 1.9 0.0044 17.1 1.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3327 PF11806.3 EKE38790.1 - 0.0023 18.2 0.6 0.27 11.5 0.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3327) TPR_7 PF13176.1 EKE38790.1 - 0.013 15.2 0.1 0.06 13.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat ChAPs PF09295.5 EKE38790.1 - 0.018 13.8 0.1 0.033 12.9 0.0 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.4 EKE38790.1 - 0.073 12.3 0.1 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.1 EKE38790.1 - 0.9 10.1 3.3 4.4 7.9 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1282 PF06930.7 EKE38791.1 - 0.00026 20.7 2.1 0.00026 20.7 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) SUR7 PF06687.7 EKE38791.1 - 0.025 14.1 3.0 0.027 14.0 2.1 1.1 1 0 0 1 1 1 0 SUR7/PalI family Oxidored_q3 PF00499.15 EKE38791.1 - 0.073 12.8 9.9 0.089 12.5 6.9 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TspO_MBR PF03073.10 EKE38791.1 - 0.11 12.0 6.6 0.24 10.9 4.6 1.6 1 1 0 1 1 1 0 TspO/MBR family DUF2723 PF11028.3 EKE38791.1 - 0.39 10.1 4.6 0.47 9.9 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) DUF2207 PF09972.4 EKE38791.1 - 0.65 8.5 4.8 0.71 8.3 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 EKE38791.1 - 0.82 9.6 12.1 1 9.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function YfhO PF09586.5 EKE38791.1 - 2.5 6.0 9.8 2.9 5.7 6.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4064 PF13273.1 EKE38791.1 - 9.5 6.3 16.2 64 3.7 11.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Sulfotransfer_3 PF13469.1 EKE38792.1 - 5.4e-06 27.4 0.0 1.5e-05 25.9 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE38792.1 - 1.2e-05 24.6 1.2 5.1e-05 22.6 0.8 1.9 1 1 0 1 1 1 1 Sulfotransferase domain DDE_Tnp_IS1595 PF12762.2 EKE38792.1 - 0.1 12.4 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 ISXO2-like transposase domain Astro_capsid PF03115.9 EKE38793.1 - 0.13 10.5 8.3 0.21 9.8 5.8 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CRA PF06589.6 EKE38793.1 - 0.15 11.3 0.0 0.15 11.3 0.0 2.8 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) Ras PF00071.17 EKE38794.1 - 5.9e-43 146.0 0.3 7.3e-43 145.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38794.1 - 1.2e-17 64.5 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38794.1 - 2.4e-16 59.4 0.1 3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EKE38794.1 - 1.4e-06 28.5 0.0 3.1e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EKE38794.1 - 1.7e-06 27.3 0.1 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE38794.1 - 8.5e-06 25.7 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE38794.1 - 6.6e-05 22.4 0.1 0.00033 20.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE38794.1 - 0.00021 20.5 0.1 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EKE38794.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EKE38794.1 - 0.011 15.2 0.4 0.18 11.3 0.0 2.4 1 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EKE38794.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EKE38794.1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EKE38794.1 - 0.027 13.6 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 KaiC Septin PF00735.13 EKE38794.1 - 0.035 13.1 0.1 0.052 12.5 0.1 1.3 1 0 0 1 1 1 0 Septin T2SE PF00437.15 EKE38794.1 - 0.065 12.1 0.1 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 EKE38794.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EKE38794.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DOCK-C2 PF14429.1 EKE38795.1 - 4.2e-36 124.3 6.3 7.6e-36 123.4 3.2 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF1107 PF06526.7 EKE38796.1 - 0.036 13.8 0.2 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1107) RhoGAP PF00620.22 EKE38797.1 - 1.5e-32 112.3 1.7 9.2e-32 109.7 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EKE38797.1 - 1.4e-12 47.7 4.2 1.4e-12 47.7 2.9 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EKE38797.1 - 0.00029 20.3 1.9 0.00077 18.9 1.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain DUF572 PF04502.8 EKE38798.1 - 2.4e-37 128.8 0.9 2.7e-37 128.7 0.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.6 EKE38798.1 - 0.15 11.5 1.5 9.8 5.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) ubiquitin PF00240.18 EKE38799.1 - 0.00016 21.0 1.5 0.00032 20.0 1.1 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EKE38799.1 - 0.0025 17.9 0.6 0.008 16.3 0.2 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UBA PF00627.26 EKE38799.1 - 0.077 12.8 2.1 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 UBA/TS-N domain DUF2404 PF10296.4 EKE38800.1 - 8.8e-16 57.8 0.3 3.5e-15 55.9 0.1 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Staphostatin_B PF09023.5 EKE38801.1 - 0.00015 21.5 0.1 0.00043 20.0 0.1 1.7 1 0 0 1 1 1 1 Staphostatin B DUF4179 PF13786.1 EKE38803.1 - 2.1 8.6 0.0 2.1 8.6 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4179) RAMPs PF03787.10 EKE38804.1 - 2 8.2 5.5 2.7 7.7 3.7 1.3 1 1 0 1 1 1 0 RAMP superfamily PspB PF06667.7 EKE38805.1 - 0.079 12.9 0.3 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 Phage shock protein B RhoGEF PF00621.15 EKE38807.1 - 4e-10 39.8 10.4 4e-10 39.8 7.2 2.4 2 0 0 2 2 2 1 RhoGEF domain FCH PF00611.18 EKE38808.1 - 9.5e-05 22.5 0.2 9.5e-05 22.5 0.1 3.5 2 1 2 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SNARE PF05739.14 EKE38808.1 - 0.034 13.8 5.6 0.071 12.8 3.0 2.3 2 0 0 2 2 2 0 SNARE domain P22_AR_C PF10548.4 EKE38808.1 - 0.13 12.0 3.1 0.28 11.0 0.2 2.7 2 1 1 3 3 3 0 P22AR C-terminal domain Pkinase_Tyr PF07714.12 EKE38809.1 - 1.5e-59 201.1 0.0 2.2e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38809.1 - 4e-55 186.7 0.0 7.8e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 EKE38809.1 - 1.2e-10 41.1 11.1 1.9e-08 34.1 1.0 3.6 4 0 0 4 4 4 2 IPT/TIG domain APH PF01636.18 EKE38809.1 - 0.095 12.4 0.0 0.43 10.2 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family TLD PF07534.11 EKE38811.1 - 5.7e-07 29.6 0.5 1.1e-06 28.7 0.3 1.7 1 1 0 1 1 1 1 TLD FAT PF02259.18 EKE38812.1 - 8e-67 225.7 20.1 8.5e-65 219.0 8.2 2.9 2 1 0 2 2 2 2 FAT domain Rapamycin_bind PF08771.6 EKE38812.1 - 1.2e-28 99.1 0.1 1.2e-28 99.1 0.1 3.6 4 0 0 4 4 4 1 Rapamycin binding domain TPR_19 PF14559.1 EKE38812.1 - 0.00013 22.1 5.5 0.0079 16.5 0.1 4.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKE38812.1 - 0.00037 20.0 8.1 0.0031 17.1 0.1 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKE38812.1 - 0.007 15.9 3.8 0.16 11.6 0.0 4.3 5 0 0 5 5 5 1 TPR repeat TPR_6 PF13174.1 EKE38812.1 - 0.028 14.8 1.0 28 5.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Flg_bbr_C PF06429.8 EKE38812.1 - 0.032 14.1 0.5 0.11 12.4 0.3 1.9 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal Docking PF08990.6 EKE38812.1 - 0.7 9.1 3.6 1.1 8.5 0.2 2.5 2 0 0 2 2 2 0 Erythronolide synthase docking C2 PF00168.25 EKE38813.1 - 3.8e-31 106.7 0.8 1.1e-16 60.3 0.0 3.3 3 0 0 3 3 3 2 C2 domain LCAT PF02450.10 EKE38814.1 - 8.7e-30 103.9 6.1 5.5e-28 98.0 1.6 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EKE38814.1 - 0.0045 16.6 0.0 0.027 14.0 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Rsd_AlgQ PF04353.8 EKE38814.1 - 0.073 12.7 0.1 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Abhydrolase_5 PF12695.2 EKE38814.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lactamase_B PF00753.22 EKE38815.1 - 5.5e-13 49.0 0.0 9.7e-12 44.9 0.0 2.4 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Flavodoxin_1 PF00258.20 EKE38815.1 - 3.7e-08 33.4 0.0 6.8e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 EKE38815.1 - 0.0038 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain DUF1256 PF06866.6 EKE38815.1 - 0.0062 15.7 0.6 0.16 11.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1256) Lactamase_B_2 PF12706.2 EKE38815.1 - 0.012 15.1 0.2 0.084 12.4 0.1 2.0 1 1 1 2 2 2 0 Beta-lactamase superfamily domain IPK PF03770.11 EKE38816.1 - 3e-35 121.6 3.2 7.2e-35 120.4 2.2 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Peptidase_S74 PF13884.1 EKE38817.1 - 3.6e-11 43.0 0.0 6.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Flg_bbr_C PF06429.8 EKE38817.1 - 0.047 13.5 0.4 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal DUF1212 PF06738.7 EKE38817.1 - 0.69 9.3 5.8 1.5 8.2 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Spore_YhaL PF14147.1 EKE38817.1 - 0.78 9.2 2.6 2.7 7.5 1.8 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL Thi4 PF01946.12 EKE38818.1 - 0.13 11.3 1.5 0.26 10.3 0.2 2.0 2 0 0 2 2 2 0 Thi4 family DUF4337 PF14235.1 EKE38818.1 - 4.6 7.0 7.8 1.5 8.6 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF607 PF04678.8 EKE38818.1 - 5.2 6.9 7.8 5.6 6.8 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Bax1-I PF01027.15 EKE38819.1 - 0.0069 16.0 20.2 0.0099 15.4 14.0 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Methyltransf_28 PF02636.12 EKE38820.1 - 0.025 13.9 0.3 0.032 13.6 0.2 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Aminotran_1_2 PF00155.16 EKE38820.1 - 0.079 11.8 0.3 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HECA PF15353.1 EKE38820.1 - 4.2 7.1 9.8 0.83 9.3 1.0 2.4 1 1 0 2 2 2 0 Headcase protein family homologue RNase_P_p30 PF01876.11 EKE38822.1 - 1e-33 115.6 0.0 1.9e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 Oxysterol_BP PF01237.13 EKE38822.1 - 3.8e-11 42.0 2.0 6.4e-11 41.3 1.4 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein K-box PF01486.12 EKE38822.1 - 0.0016 18.1 0.6 0.004 16.9 0.4 1.6 1 0 0 1 1 1 1 K-box region Fic_N PF13784.1 EKE38822.1 - 0.1 12.4 0.1 0.32 10.8 0.1 1.8 1 0 0 1 1 1 0 Fic/DOC family N-terminal Hypoth_Ymh PF09509.5 EKE38822.1 - 0.11 12.1 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) DUF3994 PF13159.1 EKE38822.1 - 7.2 6.9 9.2 2.2 8.5 0.4 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3994) V-ATPase_G PF03179.10 EKE38823.1 - 4.3e-19 68.7 22.0 4.7e-19 68.6 15.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF2362 PF10154.4 EKE38823.1 - 0.034 12.8 7.1 0.04 12.5 4.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF4085 PF13315.1 EKE38823.1 - 0.067 12.5 9.5 0.074 12.4 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Cupin_8 PF13621.1 EKE38823.1 - 0.14 11.6 5.6 0.17 11.3 3.9 1.0 1 0 0 1 1 1 0 Cupin-like domain Nop25 PF09805.4 EKE38823.1 - 0.27 11.2 16.6 0.35 10.9 11.5 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Lipase PF00151.14 EKE38823.1 - 0.28 10.3 4.9 0.32 10.1 3.4 1.0 1 0 0 1 1 1 0 Lipase TFIIE_alpha PF02002.12 EKE38823.1 - 0.3 10.6 7.9 0.92 9.0 5.4 1.9 1 1 0 1 1 1 0 TFIIE alpha subunit DUF1451 PF07295.6 EKE38823.1 - 0.39 10.4 8.1 0.48 10.1 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF3323 PF11796.3 EKE38823.1 - 0.39 10.0 6.4 0.46 9.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) T2SF PF00482.18 EKE38823.1 - 0.46 10.4 1.9 0.56 10.1 1.3 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F KfrA_N PF11740.3 EKE38823.1 - 0.47 10.9 16.2 0.057 13.8 6.0 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Peptidase_M75 PF09375.5 EKE38823.1 - 0.5 9.6 9.5 1.3 8.2 5.3 1.8 1 1 1 2 2 2 0 Imelysin ATP-synt_B PF00430.13 EKE38823.1 - 0.53 10.0 23.0 1.3 8.8 15.9 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Exonuc_VII_L PF02601.10 EKE38823.1 - 0.54 9.3 11.3 0.64 9.1 7.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.6 EKE38823.1 - 0.56 9.3 11.6 0.66 9.1 8.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3834 PF12916.2 EKE38823.1 - 0.64 8.9 4.2 0.74 8.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) DUF3584 PF12128.3 EKE38823.1 - 0.71 7.1 15.3 0.84 6.8 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PMI_typeI PF01238.16 EKE38823.1 - 0.91 8.4 7.9 1.1 8.2 5.5 1.0 1 0 0 1 1 1 0 Phosphomannose isomerase type I Toxin_41 PF15521.1 EKE38823.1 - 1.1 8.4 9.5 1.8 7.6 6.5 1.5 1 1 0 1 1 1 0 Putative toxin 41 RR_TM4-6 PF06459.7 EKE38823.1 - 1.2 9.0 12.4 1.4 8.7 8.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ApoO PF09769.4 EKE38823.1 - 1.4 8.6 4.4 2.9 7.5 3.1 1.5 1 1 0 1 1 1 0 Apolipoprotein O DUF3435 PF11917.3 EKE38823.1 - 1.5 7.4 8.8 1.6 7.3 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) VitK2_biosynth PF02621.9 EKE38823.1 - 1.6 7.8 5.7 1.6 7.8 3.5 1.4 1 1 0 1 1 1 0 Menaquinone biosynthesis Prominin PF05478.6 EKE38823.1 - 1.9 5.9 7.8 1.9 5.9 5.4 1.0 1 0 0 1 1 1 0 Prominin FAM60A PF15396.1 EKE38823.1 - 2.1 8.0 7.1 2.5 7.8 4.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2852 PF11014.3 EKE38823.1 - 2.3 8.2 7.1 0.47 10.4 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Paramyxo_ncap PF00973.14 EKE38823.1 - 2.4 6.7 7.4 2.5 6.6 5.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein IncA PF04156.9 EKE38823.1 - 3.1 7.3 9.1 4.6 6.8 6.3 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EKE38823.1 - 4 6.3 14.8 4.8 6.1 10.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EKE38823.1 - 4.2 6.2 11.2 4.4 6.1 7.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4011 PF13195.1 EKE38823.1 - 4.6 7.2 8.3 5.6 6.9 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DUF3708 PF12501.3 EKE38823.1 - 5.8 6.7 6.0 9.1 6.0 4.1 1.4 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF883 PF05957.8 EKE38823.1 - 6.1 7.3 11.2 5.9 7.3 3.9 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Sds3 PF08598.6 EKE38823.1 - 6.3 6.2 14.9 10 5.6 10.3 1.3 1 1 0 1 1 1 0 Sds3-like WD40 PF00400.27 EKE38824.1 - 0.019 14.8 0.3 9.6 6.2 0.2 3.4 2 1 1 3 3 3 0 WD domain, G-beta repeat Adap_comp_sub PF00928.16 EKE38825.1 - 0.00053 19.1 0.1 0.00078 18.6 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family SNARE PF05739.14 EKE38826.1 - 1.7e-07 30.8 1.5 2.3e-07 30.3 1.0 1.2 1 0 0 1 1 1 1 SNARE domain AAA_13 PF13166.1 EKE38826.1 - 0.0015 17.0 0.6 0.0018 16.8 0.4 1.0 1 0 0 1 1 1 1 AAA domain COG2 PF06148.6 EKE38826.1 - 0.0022 17.8 0.2 0.0029 17.4 0.1 1.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PilJ PF13675.1 EKE38826.1 - 0.0024 18.1 0.1 0.0031 17.8 0.0 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF16 PF01519.11 EKE38826.1 - 0.0043 17.2 1.1 0.0056 16.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF724 PF05266.9 EKE38826.1 - 0.0051 16.4 1.0 0.0057 16.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Prefoldin_2 PF01920.15 EKE38826.1 - 0.007 16.1 1.9 0.016 14.9 0.9 1.7 1 1 1 2 2 2 1 Prefoldin subunit Phage_GP20 PF06810.6 EKE38826.1 - 0.0096 15.3 1.6 0.051 13.0 0.5 2.0 1 1 1 2 2 2 1 Phage minor structural protein GP20 ALIX_LYPXL_bnd PF13949.1 EKE38826.1 - 0.011 14.6 0.5 0.014 14.3 0.4 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TFR_dimer PF04253.10 EKE38826.1 - 0.015 14.8 0.1 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain RmuC PF02646.11 EKE38826.1 - 0.019 13.7 0.4 0.023 13.5 0.3 1.1 1 0 0 1 1 1 0 RmuC family CENP-Q PF13094.1 EKE38826.1 - 0.023 14.7 0.3 0.027 14.5 0.2 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 EKE38826.1 - 0.025 13.5 0.2 0.03 13.2 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 End3 PF12761.2 EKE38826.1 - 0.027 14.1 1.2 0.032 13.8 0.8 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FH2 PF02181.18 EKE38826.1 - 0.032 13.1 0.4 0.035 12.9 0.3 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain Nsp1_C PF05064.8 EKE38826.1 - 0.033 13.8 0.8 0.043 13.4 0.6 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region Uso1_p115_C PF04871.8 EKE38826.1 - 0.034 14.0 1.4 0.045 13.6 1.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.4 EKE38826.1 - 0.036 14.1 2.9 0.053 13.6 2.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 EKE38826.1 - 0.038 12.6 1.0 0.043 12.4 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 EKE38826.1 - 0.041 13.4 1.2 0.05 13.1 0.8 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 EKE38826.1 - 0.044 13.5 1.0 0.054 13.2 0.7 1.1 1 0 0 1 1 1 0 Laminin Domain II ADIP PF11559.3 EKE38826.1 - 0.054 13.3 0.7 0.064 13.1 0.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MscS_porin PF12795.2 EKE38826.1 - 0.058 12.7 0.7 0.072 12.3 0.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.7 EKE38826.1 - 0.058 13.6 1.2 0.17 12.1 0.8 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EKE38826.1 - 0.072 12.2 0.1 0.087 11.9 0.1 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein STAT_alpha PF01017.15 EKE38826.1 - 0.081 12.6 0.7 0.23 11.1 0.2 1.7 1 1 1 2 2 2 0 STAT protein, all-alpha domain Cauli_AT PF03233.8 EKE38826.1 - 0.083 12.5 0.7 0.098 12.3 0.5 1.1 1 0 0 1 1 1 0 Aphid transmission protein ATG16 PF08614.6 EKE38826.1 - 0.09 12.5 1.9 0.11 12.3 1.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 EKE38826.1 - 0.093 12.3 0.6 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 Mnd1 family Prefoldin PF02996.12 EKE38826.1 - 0.095 12.3 1.3 0.21 11.2 0.9 1.5 1 1 0 1 1 1 0 Prefoldin subunit HOOK PF05622.7 EKE38826.1 - 0.1 10.4 1.2 0.12 10.1 0.8 1.0 1 0 0 1 1 1 0 HOOK protein Cortex-I_coil PF09304.5 EKE38826.1 - 0.1 12.6 1.0 0.16 12.0 0.7 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil SlyX PF04102.7 EKE38826.1 - 0.11 12.9 1.8 0.54 10.6 1.0 1.9 1 1 1 2 2 2 0 SlyX RPAP1_N PF08621.5 EKE38826.1 - 0.13 11.8 2.4 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF4319 PF14203.1 EKE38826.1 - 0.13 11.7 1.0 0.26 10.8 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4319) ApoC-I PF04691.7 EKE38826.1 - 0.15 11.7 0.8 0.25 11.0 0.6 1.4 1 1 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DUF2205 PF10224.4 EKE38826.1 - 0.17 11.4 2.0 1.1 8.8 0.2 2.0 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) EAP30 PF04157.11 EKE38826.1 - 0.2 10.7 2.3 0.31 10.1 1.2 1.5 1 1 0 1 1 1 0 EAP30/Vps36 family TMF_DNA_bd PF12329.3 EKE38826.1 - 0.25 11.1 2.9 0.23 11.2 0.7 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CorA PF01544.13 EKE38826.1 - 2.9 6.8 5.8 0.3 10.0 0.4 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Synaptobrevin PF00957.16 EKE38826.1 - 6.4 6.4 7.5 33 4.1 5.1 2.2 1 1 0 1 1 1 0 Synaptobrevin Lactamase_B PF00753.22 EKE38827.1 - 0.00013 21.7 0.3 0.0003 20.5 0.1 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE38827.1 - 0.00031 20.3 1.0 0.00063 19.3 0.7 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MBOAT PF03062.14 EKE38828.1 - 3.1e-34 118.5 25.1 3.1e-34 118.5 17.4 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.20 EKE38830.1 - 7.1e-15 54.8 0.8 8.6e-15 54.5 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38830.1 - 2e-13 50.0 0.2 2.2e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L36 PF00444.13 EKE38831.1 - 0.029 14.3 0.1 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L36 RasGEF PF00617.14 EKE38832.1 - 5.1e-33 114.3 3.3 1.4e-32 112.9 2.3 1.8 1 0 0 1 1 1 1 RasGEF domain RhoGAP PF00620.22 EKE38832.1 - 0.0011 18.6 0.1 0.0081 15.7 0.1 2.4 2 0 0 2 2 2 1 RhoGAP domain SelP_N PF04592.9 EKE38833.1 - 0.0049 16.2 5.5 0.0059 16.0 3.8 1.1 1 0 0 1 1 1 1 Selenoprotein P, N terminal region RR_TM4-6 PF06459.7 EKE38833.1 - 0.053 13.4 3.7 0.056 13.3 2.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.3 EKE38833.1 - 0.34 10.5 5.1 0.43 10.2 3.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region SR-25 PF10500.4 EKE38833.1 - 0.4 10.1 17.3 2 7.8 12.3 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 EKE38833.1 - 0.81 9.4 8.2 1.2 8.8 5.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.17 EKE38833.1 - 1.3 7.9 7.6 1.6 7.6 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EKE38833.1 - 1.6 6.6 7.8 1.9 6.3 5.4 1.0 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 EKE38833.1 - 2 8.4 9.7 3.1 7.7 6.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein HSP70 PF00012.15 EKE38834.1 - 0.04 11.8 0.0 0.041 11.7 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein HSP70 PF00012.15 EKE38835.1 - 2.1e-18 65.6 0.2 2.3e-18 65.4 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.6 EKE38835.1 - 0.00052 19.0 0.0 0.00052 19.0 0.0 1.1 1 0 0 1 1 1 1 StbA protein DUF1348 PF07080.6 EKE38836.1 - 9.3 6.0 8.9 0.93 9.2 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) Flexi_CP PF00286.15 EKE38837.1 - 0.031 13.9 1.7 0.08 12.6 1.2 1.7 1 0 0 1 1 1 0 Viral coat protein ECIST_Cterm PF14784.1 EKE38837.1 - 0.69 9.8 12.1 0.38 10.7 1.6 2.6 2 1 1 3 3 3 0 C-terminal domain of the ECSIT protein Met_asp_mut_E PF06368.6 EKE38837.1 - 3.7 5.6 14.9 0.15 10.2 3.3 2.2 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) HbrB PF08539.6 EKE38837.1 - 7.2 6.4 11.2 1.9 8.3 0.8 2.4 2 0 0 2 2 2 0 HbrB-like VPS9 PF02204.13 EKE38839.1 - 0.001 19.0 1.2 0.0034 17.3 0.8 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain His_Phos_2 PF00328.17 EKE38839.1 - 0.021 14.1 0.3 0.039 13.2 0.2 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF552 PF04472.7 EKE38839.1 - 0.051 13.4 1.3 12 5.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF552) Arm PF00514.18 EKE38841.1 - 0.057 13.2 2.1 0.19 11.5 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EKE38841.1 - 0.1 13.1 0.1 10 6.7 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat SbcD_C PF12320.3 EKE38843.1 - 0.053 13.5 0.7 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain GTP_EFTU PF00009.22 EKE38844.1 - 3e-07 30.0 0.1 3.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MFS_1 PF07690.11 EKE38845.1 - 1e-27 96.8 21.6 1.5e-22 79.8 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ninjurin PF04923.7 EKE38845.1 - 0.064 12.9 2.8 0.17 11.6 0.0 2.9 4 0 0 4 4 4 0 Ninjurin SlyX PF04102.7 EKE38846.1 - 0.086 13.2 3.6 5.4 7.4 0.5 2.5 2 0 0 2 2 2 0 SlyX Pyridox_ox_2 PF12900.2 EKE38848.1 - 1e-16 61.0 0.0 1.2e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EKE38848.1 - 4e-06 26.7 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Spatacsin_C PF14649.1 EKE38849.1 - 1.2e-20 73.6 7.2 8.9e-20 70.7 1.8 2.6 2 0 0 2 2 2 2 Spatacsin C-terminus PP2C PF00481.16 EKE38849.1 - 0.036 13.4 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein phosphatase 2C Syja_N PF02383.13 EKE38850.1 - 2.4e-81 272.9 8.9 4.1e-81 272.2 6.2 1.3 1 0 0 1 1 1 1 SacI homology domain AMP-binding PF00501.23 EKE38851.1 - 3.4e-48 164.0 0.0 5e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKE38851.1 - 4.7e-30 104.3 0.0 7.1e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EKE38851.1 - 1.6e-06 27.0 0.2 2.9e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EKE38851.1 - 1.1e-05 25.5 0.5 3.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EKE38851.1 - 0.00028 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKE38851.1 - 0.00039 20.4 0.0 0.04 13.9 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EKE38851.1 - 0.095 11.5 0.0 0.49 9.2 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Methyltransf_18 PF12847.2 EKE38852.1 - 3.2e-06 27.6 0.1 1.1e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EKE38852.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 EKE38852.1 - 0.1 11.2 0.1 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PNP_UDP_1 PF01048.15 EKE38852.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily Methyltransf_23 PF13489.1 EKE38852.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain RRM_1 PF00076.17 EKE38853.1 - 9.7e-30 102.0 0.8 1.4e-14 53.4 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE38853.1 - 2.6e-22 78.5 0.3 3.7e-11 42.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE38853.1 - 4.3e-17 61.7 0.7 6e-10 38.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EKE38853.1 - 0.0013 18.4 0.3 0.0028 17.3 0.2 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EKE38853.1 - 0.0037 17.0 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EKE38853.1 - 0.087 12.5 0.2 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Limkain b1 RRM_3 PF08777.6 EKE38853.1 - 0.16 11.8 0.9 1 9.2 0.2 2.2 2 0 0 2 2 2 0 RNA binding motif SNF2_N PF00176.18 EKE38854.1 - 6e-34 117.1 0.1 1.3e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EKE38854.1 - 4.3e-09 36.4 4.7 9.1e-07 28.8 0.0 4.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKE38854.1 - 2.1e-07 30.6 0.1 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 EKE38854.1 - 0.0018 18.0 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 2 Flavivirus DEAD domain Cwf_Cwc_15 PF04889.7 EKE38855.1 - 0.45 10.2 12.0 0.58 9.8 8.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYVE_2 PF02318.11 EKE38855.1 - 0.49 10.3 6.1 0.4 10.5 1.9 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger BTV_NS2 PF04514.7 EKE38855.1 - 3.3 6.5 8.6 4.1 6.1 6.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 T4-Gluco-transf PF09198.5 EKE38856.1 - 0.3 10.4 3.6 0.34 10.2 0.2 2.7 2 1 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase RRM_1 PF00076.17 EKE38857.1 - 1.7e-36 123.6 0.4 6.8e-19 67.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE38857.1 - 6.1e-24 83.7 0.0 3.2e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE38857.1 - 5.3e-21 74.2 1.7 2.2e-11 43.4 0.3 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE38857.1 - 0.017 14.8 0.3 4.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EKE38857.1 - 0.15 11.9 0.1 0.15 11.9 0.1 3.0 3 0 0 3 3 3 0 RNA binding motif MIG-14_Wnt-bd PF06664.7 EKE38858.1 - 4.9e-29 101.0 43.5 4.9e-29 101.0 30.1 2.0 3 0 0 3 3 3 1 Wnt-binding factor required for Wnt secretion hNIFK_binding PF12196.3 EKE38858.1 - 0.042 13.2 4.8 0.042 13.2 0.7 2.6 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK DUF1469 PF07332.6 EKE38858.1 - 0.41 10.3 9.6 2 8.1 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) SET PF00856.23 EKE38859.1 - 3.7e-12 46.8 1.2 1.9e-11 44.5 0.0 2.4 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 EKE38859.1 - 5.3e-10 38.8 0.1 1.2e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EKE38859.1 - 6.1e-09 35.1 0.8 0.00073 19.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKE38859.1 - 2.2e-08 33.3 2.7 0.0038 16.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKE38859.1 - 4.6e-06 26.0 1.0 0.011 15.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE38859.1 - 3.4e-05 23.7 0.0 0.00018 21.3 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE38859.1 - 0.00081 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat YfiO PF13525.1 EKE38859.1 - 0.0022 17.4 1.3 0.0035 16.8 0.9 1.3 1 0 0 1 1 1 1 Outer membrane lipoprotein Apc3 PF12895.2 EKE38859.1 - 0.0024 17.9 0.2 0.0024 17.9 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EKE38859.1 - 0.0043 16.7 0.1 1.4 8.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKE38859.1 - 0.029 15.0 0.0 0.05 14.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE38859.1 - 0.065 13.7 0.1 17 6.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 EKE38859.1 - 0.49 10.4 5.0 0.64 10.1 0.3 3.3 4 0 0 4 4 4 0 PPR repeat TPR_3 PF07720.7 EKE38859.1 - 2.6 7.9 10.3 7 6.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat GM_CSF PF01109.12 EKE38860.1 - 0.023 14.6 0.5 0.053 13.4 0.4 1.6 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor ATP_bind_1 PF03029.12 EKE38861.1 - 6.6e-66 222.2 0.2 1.1e-65 221.5 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EKE38861.1 - 1.3e-06 28.3 0.1 3.6e-06 26.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EKE38861.1 - 3.4e-06 27.8 1.7 1.9e-05 25.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EKE38861.1 - 3.6e-06 26.5 5.0 0.00012 21.5 0.0 2.6 3 1 0 3 3 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EKE38861.1 - 0.00016 20.8 7.1 0.00053 19.1 0.1 3.0 3 0 0 3 3 3 1 AIG1 family AAA_33 PF13671.1 EKE38861.1 - 0.00016 21.5 1.5 0.00021 21.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKE38861.1 - 0.00016 21.9 0.3 0.0017 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EKE38861.1 - 0.00085 18.6 0.4 0.21 10.8 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B CbiA PF01656.18 EKE38861.1 - 0.0019 17.6 0.9 0.0028 17.0 0.1 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 EKE38861.1 - 0.0028 17.2 0.1 0.0028 17.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKE38861.1 - 0.0037 16.1 0.6 0.01 14.7 0.0 1.9 2 1 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 EKE38861.1 - 0.0039 16.6 0.4 0.014 14.8 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 EKE38861.1 - 0.0044 17.2 0.2 0.037 14.2 0.0 2.4 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EKE38861.1 - 0.0067 15.9 1.8 0.11 11.9 0.1 3.1 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EKE38861.1 - 0.009 16.3 0.4 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SRP54 PF00448.17 EKE38861.1 - 0.011 15.2 0.1 0.082 12.3 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EKE38861.1 - 0.011 15.9 0.1 0.047 13.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EKE38861.1 - 0.012 15.0 1.0 0.11 11.9 0.1 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 EKE38861.1 - 0.014 14.5 4.9 0.075 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EKE38861.1 - 0.014 14.5 0.1 0.093 11.9 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE38861.1 - 0.015 15.3 0.0 0.058 13.3 0.0 1.9 2 1 1 3 3 2 0 AAA ATPase domain AAA_30 PF13604.1 EKE38861.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EKE38861.1 - 0.019 14.6 0.1 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SBF2 PF12335.3 EKE38861.1 - 0.02 14.2 0.9 0.032 13.5 0.6 1.2 1 0 0 1 1 1 0 Myotubularin protein Miro PF08477.8 EKE38861.1 - 0.023 15.1 1.3 0.2 12.1 0.1 2.9 2 1 0 2 2 1 0 Miro-like protein Zeta_toxin PF06414.7 EKE38861.1 - 0.027 13.5 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin LCM PF04072.9 EKE38861.1 - 0.034 13.7 0.1 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Thioredoxin_7 PF13899.1 EKE38861.1 - 0.034 14.1 0.7 0.078 13.0 0.0 2.0 2 0 0 2 2 1 0 Thioredoxin-like Arf PF00025.16 EKE38861.1 - 0.058 12.6 1.3 0.099 11.8 0.1 2.1 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_5 PF07728.9 EKE38861.1 - 0.064 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EKE38861.1 - 0.065 13.4 0.5 2.7 8.1 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.1 EKE38861.1 - 0.065 13.1 1.3 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EKE38861.1 - 0.072 12.7 0.6 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 NTPase MobB PF03205.9 EKE38861.1 - 0.091 12.4 0.1 0.091 12.4 0.1 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EKE38861.1 - 0.12 11.8 3.0 0.77 9.1 2.0 2.0 1 1 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 EKE38861.1 - 0.12 12.1 1.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 EKE38861.1 - 0.16 11.9 1.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 EKE38861.1 - 0.18 10.9 7.2 0.017 14.2 0.7 2.2 2 1 0 2 2 1 0 Gtr1/RagA G protein conserved region T2SE PF00437.15 EKE38861.1 - 0.19 10.6 0.1 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.5 EKE38861.1 - 0.2 10.8 0.1 0.2 10.8 0.1 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EKE38861.1 - 0.24 11.1 5.8 3 7.6 0.0 3.2 3 0 0 3 3 3 0 Dynamin family Thioredoxin_2 PF13098.1 EKE38861.1 - 0.82 9.8 5.6 2.6 8.2 2.5 2.5 2 1 0 2 2 1 0 Thioredoxin-like domain DUF3987 PF13148.1 EKE38861.1 - 0.84 8.1 2.6 7.4 5.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Clat_adaptor_s PF01217.15 EKE38862.1 - 6.6e-16 58.3 0.4 7.2e-16 58.1 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Myb_DNA-bind_6 PF13921.1 EKE38863.1 - 4.3e-24 84.3 1.7 9.4e-16 57.6 0.3 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKE38863.1 - 4.3e-24 84.2 0.2 1.1e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EKE38863.1 - 0.0014 18.3 0.4 0.57 10.0 0.0 2.9 1 1 1 2 2 2 2 Rap1 Myb domain SLIDE PF09111.5 EKE38863.1 - 0.002 17.8 0.2 0.069 12.8 0.0 2.2 1 1 1 2 2 2 1 SLIDE DUF4085 PF13315.1 EKE38863.1 - 0.0042 16.4 0.3 0.013 14.8 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4085) Glypican PF01153.14 EKE38863.1 - 0.054 12.1 0.4 0.058 12.0 0.3 1.1 1 0 0 1 1 1 0 Glypican DUF3703 PF12487.3 EKE38863.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) Myb_DNA-bind_4 PF13837.1 EKE38863.1 - 0.31 11.1 5.2 2.3 8.4 1.9 3.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HHH_2 PF12826.2 EKE38864.1 - 0.0089 15.8 1.0 0.18 11.6 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif RabGAP-TBC PF00566.13 EKE38865.1 - 6e-36 123.9 6.4 9.6e-36 123.2 4.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4300 PF14133.1 EKE38865.1 - 0.00076 18.8 0.7 0.0013 18.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4300) CKAP2_C PF15297.1 EKE38865.1 - 0.023 13.5 0.2 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus PI3_PI4_kinase PF00454.22 EKE38867.1 - 3.1e-33 115.2 0.1 1.3e-32 113.1 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EKE38867.1 - 1.1e-13 50.8 0.0 2.3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 EKE38867.1 - 0.00027 20.0 0.0 0.0019 17.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4135) PI3K_C2 PF00792.19 EKE38867.1 - 0.003 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF2458 PF10454.4 EKE38867.1 - 0.011 15.5 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) SHQ1 PF04925.10 EKE38868.1 - 8.3e-39 132.9 1.4 8.3e-39 132.9 1.0 2.0 2 0 0 2 2 2 1 SHQ1 protein Membr_traf_MHD PF10540.4 EKE38868.1 - 0.095 12.4 2.7 0.62 9.8 0.1 2.3 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain Orbi_VP5 PF00901.12 EKE38868.1 - 0.25 9.4 5.1 0.41 8.7 3.5 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 ubiquitin PF00240.18 EKE38869.1 - 0.032 13.6 0.6 0.36 10.2 0.1 2.7 2 1 0 2 2 2 0 Ubiquitin family DUF713 PF05218.9 EKE38869.1 - 0.041 13.6 4.9 0.05 13.3 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF713) BTB_2 PF02214.17 EKE38871.1 - 0.00012 22.1 0.5 0.00036 20.6 0.4 1.8 1 0 0 1 1 1 1 BTB/POZ domain Rep_fac_C PF08542.6 EKE38871.1 - 1.7 8.6 5.8 19 5.2 0.1 4.1 3 2 1 4 4 4 0 Replication factor C C-terminal domain Lipase_3 PF01764.20 EKE38872.1 - 4.1e-08 32.9 0.0 7.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EKE38872.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EKE38872.1 - 0.062 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family E1-E2_ATPase PF00122.15 EKE38872.1 - 0.065 12.2 2.7 0.21 10.6 0.0 2.7 3 0 0 3 3 3 0 E1-E2 ATPase SLAC1 PF03595.12 EKE38872.1 - 1.3 7.5 13.5 0.29 9.7 6.0 1.9 2 0 0 2 2 2 0 Voltage-dependent anion channel Viral_Beta_CD PF04530.7 EKE38872.1 - 3 8.0 8.2 0.32 11.1 0.2 3.0 3 0 0 3 3 3 0 Viral Beta C/D like family HemY_N PF07219.8 EKE38872.1 - 3.3 7.3 5.5 34 4.0 0.8 3.4 3 0 0 3 3 3 0 HemY protein N-terminus Met_10 PF02475.11 EKE38874.1 - 1.5e-53 181.3 0.3 1.5e-53 181.3 0.2 1.9 2 0 0 2 2 2 1 Met-10+ like-protein TRM PF02005.11 EKE38874.1 - 0.00038 19.5 0.4 0.00062 18.8 0.0 1.5 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EKE38874.1 - 0.0004 19.9 0.2 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EKE38874.1 - 0.0027 17.2 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EKE38874.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EKE38874.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Indigoidine_A PF04227.7 EKE38874.1 - 0.037 13.2 0.1 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Indigoidine synthase A like protein SYS1 PF09801.4 EKE38875.1 - 3.5e-05 23.8 0.2 4.2e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Pkinase PF00069.20 EKE38876.1 - 1.1e-58 198.4 0.2 1.3e-58 198.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38876.1 - 3.4e-38 131.2 0.1 4e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE38876.1 - 1.5e-07 30.7 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EKE38876.1 - 0.00021 20.6 0.3 0.0003 20.1 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EKE38876.1 - 0.0021 17.1 0.6 0.0032 16.5 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE38876.1 - 0.015 15.0 0.2 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKE38876.1 - 0.024 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ras PF00071.17 EKE38877.1 - 9.9e-12 44.5 0.0 1.5e-11 43.9 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKE38877.1 - 6.6e-09 36.3 0.0 3.1e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE38877.1 - 6.2e-05 22.3 0.0 7.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE38877.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EKE38877.1 - 0.0064 15.2 0.1 0.73 8.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.13 EKE38877.1 - 0.024 13.9 0.1 4.9 6.4 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.9 EKE38877.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_S24 PF00717.18 EKE38877.1 - 0.07 12.7 0.2 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase S24-like AAA_25 PF13481.1 EKE38877.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CobU PF02283.11 EKE38877.1 - 0.14 11.5 0.0 0.88 8.9 0.0 2.0 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ATP_bind_3 PF01171.15 EKE38879.1 - 1.1e-18 67.4 0.0 1.5e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EKE38879.1 - 0.0038 16.1 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 EKE38879.1 - 0.007 14.9 0.0 0.012 14.2 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase DUF208 PF02677.9 EKE38879.1 - 0.012 15.4 0.2 0.26 11.0 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized BCR, COG1636 PHP PF02811.14 EKE38879.1 - 0.023 14.5 0.1 0.045 13.5 0.0 1.6 1 1 0 1 1 1 0 PHP domain ATP_bind_4 PF01902.12 EKE38879.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-binding region zinc_ribbon_2 PF13240.1 EKE38879.1 - 0.051 13.0 0.4 0.16 11.4 0.3 1.9 1 0 0 1 1 1 0 zinc-ribbon domain IF2_N PF04760.10 EKE38880.1 - 0.003 17.1 1.7 2.7 7.7 0.1 2.9 3 0 0 3 3 3 2 Translation initiation factor IF-2, N-terminal region DUF2508 PF10704.4 EKE38880.1 - 0.03 14.4 5.8 0.074 13.2 0.4 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF2508) Flexi_CP PF00286.15 EKE38880.1 - 0.13 11.9 0.6 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 Viral coat protein DUF2408 PF10303.4 EKE38880.1 - 1 9.4 9.2 0.13 12.3 2.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) Fes1 PF08609.5 EKE38880.1 - 4.4 7.8 6.6 9.9 6.7 0.7 2.9 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 RabGAP-TBC PF00566.13 EKE38883.1 - 1.2e-12 47.8 0.7 1.6e-12 47.3 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1296 PF06972.6 EKE38883.1 - 0.0088 15.9 0.5 0.14 12.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1296) Glyco_hydro_92 PF07971.7 EKE38885.1 - 3.6e-120 401.9 6.8 4.6e-120 401.6 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 BOP1NT PF08145.7 EKE38886.1 - 7.8e-38 130.6 12.1 3e-36 125.5 8.4 2.5 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EKE38886.1 - 5.9e-16 57.6 10.9 0.0023 17.7 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Ank_2 PF12796.2 EKE38887.1 - 3.3e-06 27.3 0.1 0.00044 20.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKE38887.1 - 0.0011 18.6 0.0 0.0038 16.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EKE38887.1 - 0.0012 19.3 0.0 0.0093 16.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE38887.1 - 0.0099 16.0 0.0 0.48 10.8 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat LSM PF01423.17 EKE38889.1 - 8e-16 57.3 0.6 1.2e-15 56.8 0.4 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.13 EKE38889.1 - 0.04 14.0 0.2 0.099 12.7 0.0 1.6 1 1 1 2 2 2 0 Kringle domain RNA_pol_Rbc25 PF08292.7 EKE38889.1 - 0.075 13.2 0.1 0.11 12.7 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 CedA PF10729.4 EKE38889.1 - 0.086 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Cell division activator CedA DnaJ PF00226.26 EKE38890.1 - 8.7e-29 99.0 4.5 1.8e-28 98.0 3.1 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EKE38890.1 - 1.3e-19 69.8 2.3 3.4e-13 49.2 0.2 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain UPF0128 PF03673.8 EKE38890.1 - 0.0012 18.1 0.8 0.0025 17.1 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0128) DUF2981 PF11200.3 EKE38891.1 - 0.021 13.9 7.4 0.025 13.6 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SPX PF03105.14 EKE38891.1 - 0.1 12.3 3.8 0.13 12.0 2.7 1.1 1 0 0 1 1 1 0 SPX domain IFT57 PF10498.4 EKE38891.1 - 5.1 5.7 7.2 5.7 5.5 5.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3103 PF11301.3 EKE38892.1 - 0.07 11.8 4.8 0.077 11.6 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Rot1 PF10681.4 EKE38892.1 - 3.9 6.7 6.9 4.8 6.4 4.8 1.0 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal GAGA_bind PF06217.7 EKE38892.1 - 6.1 6.7 14.8 7.2 6.4 10.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CT47 PF15623.1 EKE38892.1 - 8.2 6.0 12.4 8.6 6.0 8.6 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 HSP70 PF00012.15 EKE38893.1 - 3.5e-62 210.1 1.8 4.1e-62 209.9 1.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE38893.1 - 1.6e-16 59.8 0.1 5.2e-16 58.1 0.0 1.9 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 EKE38893.1 - 0.0022 16.9 0.0 0.08 11.8 0.0 2.4 2 0 0 2 2 2 1 StbA protein SrfB PF07520.6 EKE38893.1 - 0.03 11.8 0.1 0.056 10.9 0.0 1.4 1 0 0 1 1 1 0 Virulence factor SrfB Hexokinase_1 PF00349.16 EKE38893.1 - 0.037 13.3 0.7 2.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Hexokinase Hydantoinase_A PF01968.13 EKE38893.1 - 0.054 12.5 0.0 0.36 9.8 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EKE38893.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain ThiF PF00899.16 EKE38894.1 - 0.092 12.5 0.0 8.9 6.1 0.0 2.7 2 1 1 3 3 3 0 ThiF family Pkinase PF00069.20 EKE38895.1 - 5.6e-55 186.2 0.5 1e-54 185.4 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38895.1 - 1.7e-51 174.7 0.2 3.3e-51 173.8 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.8 EKE38895.1 - 3e-15 55.7 492.6 0.00017 20.3 14.3 16.5 1 1 12 14 14 14 9 Giardia variant-specific surface protein TMEM154 PF15102.1 EKE38895.1 - 0.0046 16.6 0.1 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family YrbL-PhoP_reg PF10707.4 EKE38895.1 - 0.045 13.0 0.1 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EKE38895.1 - 0.056 12.5 0.1 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IncA PF04156.9 EKE38895.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 EKE38895.1 - 0.19 12.1 0.6 0.59 10.5 0.4 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.10 EKE38895.1 - 0.21 11.3 0.4 0.49 10.1 0.3 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit PspB PF06667.7 EKE38895.1 - 0.23 11.4 0.0 0.54 10.2 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B Baculo_11_kDa PF06143.6 EKE38895.1 - 1 8.8 3.9 2.5 7.4 2.7 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family RCR PF12273.3 EKE38895.1 - 1 9.8 2.1 2.1 8.9 1.5 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Motile_Sperm PF00635.21 EKE38896.1 - 0.00055 19.5 0.1 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 MSP (Major sperm protein) domain EGF_2 PF07974.8 EKE38896.1 - 0.49 10.5 10.7 0.061 13.5 3.7 2.4 1 1 1 2 2 2 0 EGF-like domain cEGF PF12662.2 EKE38896.1 - 1.6 8.4 8.3 11 5.7 5.7 2.4 1 1 0 1 1 1 0 Complement Clr-like EGF-like Ycf1 PF05758.7 EKE38898.1 - 9.5 3.7 13.1 15 3.1 9.1 1.3 1 0 0 1 1 1 0 Ycf1 Ribosomal_L37e PF01907.14 EKE38899.1 - 3e-24 84.5 12.0 4.6e-24 83.9 8.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EKE38899.1 - 0.0037 17.0 3.8 0.0052 16.5 2.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C2HC5 PF06221.8 EKE38899.1 - 0.035 13.8 3.3 0.051 13.3 2.3 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF4543 PF15076.1 EKE38899.1 - 0.078 13.0 0.1 0.097 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) zinc_ribbon_6 PF14599.1 EKE38899.1 - 0.13 12.0 4.1 0.21 11.4 2.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon FeS PF04060.8 EKE38899.1 - 0.16 11.5 1.4 2 8.0 0.1 2.3 2 0 0 2 2 2 0 Putative Fe-S cluster HypA PF01155.14 EKE38899.1 - 0.18 11.5 2.2 0.21 11.2 1.5 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EKE38899.1 - 0.24 10.6 1.8 5 6.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 EKE38899.1 - 0.25 11.0 3.3 0.93 9.2 2.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS91 PF14319.1 EKE38899.1 - 0.43 10.1 4.1 0.48 9.9 2.8 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain DNA_RNApol_7kD PF03604.8 EKE38899.1 - 0.73 9.3 7.1 1.4 8.4 0.9 2.3 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC4_3 PF13920.1 EKE38899.1 - 0.83 9.3 4.9 1.2 8.8 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tnp_zf-ribbon_2 PF13842.1 EKE38899.1 - 1.7 9.1 7.5 19 5.7 5.4 2.2 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_2 PF13923.1 EKE38899.1 - 1.9 8.6 6.4 2.7 8.0 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FdhE PF04216.7 EKE38899.1 - 2 8.0 6.2 2.2 7.9 4.3 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation SERTA PF06031.8 EKE38900.1 - 0.092 12.0 0.7 0.97 8.7 0.1 2.7 2 0 0 2 2 2 0 SERTA motif Astacin PF01400.19 EKE38901.1 - 0.04 13.3 1.1 0.07 12.5 0.8 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) MCR_beta_N PF02783.10 EKE38901.1 - 0.057 12.8 0.1 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Folliculin PF11704.3 EKE38901.1 - 0.23 11.0 1.6 0.36 10.4 1.1 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport RPAP2_Rtr1 PF04181.8 EKE38901.1 - 0.3 11.2 3.2 0.6 10.2 2.2 1.5 1 0 0 1 1 1 0 Rtr1/RPAP2 family FERM_C PF09380.5 EKE38902.1 - 0.15 12.2 3.0 0.31 11.2 2.1 1.7 1 1 0 1 1 1 0 FERM C-terminal PH-like domain DUF2373 PF10180.4 EKE38902.1 - 0.62 9.6 3.2 0.47 10.0 0.7 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) PH PF00169.24 EKE38902.1 - 0.67 10.1 4.7 0.13 12.4 0.9 1.6 2 0 0 2 2 2 0 PH domain adh_short PF00106.20 EKE38903.1 - 2.9e-13 50.0 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKE38903.1 - 5.7e-06 26.1 0.0 9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKE38903.1 - 8.3e-06 25.4 0.2 1.1e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EKE38903.1 - 6.4e-05 22.8 0.1 8.7e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EKE38903.1 - 0.015 14.2 0.7 0.021 13.7 0.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EKE38903.1 - 0.046 13.7 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Peptidase_M20 PF01546.23 EKE38904.1 - 7.6e-18 64.6 0.0 1.1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EKE38904.1 - 1.6e-07 30.4 0.0 2.9e-05 22.9 0.0 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase BssS PF13991.1 EKE38904.1 - 0.022 14.4 0.0 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 BssS protein family M20_dimer PF07687.9 EKE38904.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain RasGEF PF00617.14 EKE38905.1 - 2.1e-43 148.2 2.4 4.5e-43 147.1 1.6 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE38905.1 - 1.5e-08 34.6 5.6 1.7e-08 34.5 1.9 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF4230 PF14014.1 EKE38906.1 - 0.054 13.3 0.5 0.11 12.3 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) cwf21 PF08312.7 EKE38906.1 - 3.2 7.6 11.8 0.31 10.9 0.5 2.9 3 0 0 3 3 3 0 cwf21 domain ARGLU PF15346.1 EKE38906.1 - 8.4 6.1 12.1 0.68 9.6 3.3 2.3 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 NTP_transferase PF00483.18 EKE38907.1 - 8.1e-05 22.0 0.0 0.0005 19.4 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EKE38907.1 - 0.003 17.6 0.0 0.0042 17.1 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain MBOAT_2 PF13813.1 EKE38909.1 - 0.086 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Cornichon PF03311.9 EKE38910.1 - 6.1e-08 32.8 0.4 6.3e-08 32.8 0.3 1.0 1 0 0 1 1 1 1 Cornichon protein MGAT2 PF05060.9 EKE38911.1 - 0.01 14.7 0.1 0.016 14.1 0.1 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Ribosomal_L31e PF01198.14 EKE38912.1 - 4e-26 90.4 0.3 4e-26 90.4 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L31e Ras PF00071.17 EKE38913.1 - 4.7e-52 175.6 0.2 5.4e-52 175.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38913.1 - 3.7e-20 72.6 0.1 5.4e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38913.1 - 5.4e-08 32.2 0.1 5.9e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE38913.1 - 8.8e-08 31.7 0.7 2.5e-07 30.3 0.1 1.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE38913.1 - 0.00029 20.7 0.0 0.00062 19.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EKE38913.1 - 0.065 11.9 0.1 3.5 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit CSTF2_hinge PF14327.1 EKE38915.1 - 2e-16 59.8 0.7 2.3e-16 59.6 0.5 1.0 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Peptidase_M41 PF01434.13 EKE38915.1 - 0.063 12.7 0.2 0.066 12.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M41 CGI-121 PF08617.5 EKE38915.1 - 0.078 12.6 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase binding protein CGI-121 Taeniidae_ag PF05596.6 EKE38915.1 - 0.14 11.9 0.6 0.28 11.0 0.3 1.5 1 1 0 1 1 1 0 Taeniidae antigen APG6 PF04111.7 EKE38916.1 - 0.0028 16.7 14.5 0.0028 16.7 10.0 4.8 1 1 5 6 6 6 1 Autophagy protein Apg6 DASH_Dam1 PF08653.5 EKE38916.1 - 0.44 10.3 0.1 0.44 10.3 0.0 4.9 4 1 0 4 4 4 0 DASH complex subunit Dam1 Pox_A_type_inc PF04508.7 EKE38916.1 - 9.7 6.2 22.0 7.4 6.6 0.6 6.8 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat UFD1 PF03152.9 EKE38918.1 - 4.7e-59 198.4 0.0 5.6e-59 198.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EKE38918.1 - 0.00031 20.3 0.0 0.0008 18.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Metallophos PF00149.23 EKE38919.1 - 3.4e-19 69.0 1.4 6.7e-19 68.0 1.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE38919.1 - 3e-14 53.1 0.1 9.1e-14 51.5 0.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Mre11_DNA_bind PF04152.9 EKE38919.1 - 1.1e-08 35.0 1.4 1.1e-08 35.0 1.0 3.4 3 0 0 3 3 3 2 Mre11 DNA-binding presumed domain DUF3819 PF12842.2 EKE38919.1 - 0.014 15.1 1.1 0.014 15.1 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) CWC25 PF12542.3 EKE38921.1 - 0.03 14.7 0.3 0.047 14.1 0.1 1.3 1 1 0 1 1 1 0 Pre-mRNA splicing factor MRP-S26 PF14943.1 EKE38921.1 - 0.032 13.7 2.6 0.038 13.5 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 POX PF07526.6 EKE38921.1 - 0.076 13.2 0.9 0.13 12.5 0.1 1.7 1 1 1 2 2 2 0 Associated with HOX RXT2_N PF08595.6 EKE38921.1 - 0.1 12.4 1.4 0.11 12.2 1.0 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Lactamase_B_2 PF12706.2 EKE38922.1 - 1.5e-21 76.8 1.0 1.8e-21 76.5 0.7 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKE38922.1 - 1.1e-10 41.5 1.9 1.8e-10 40.8 1.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EKE38922.1 - 0.00015 21.5 0.2 0.00043 20.0 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain GtrA PF04138.9 EKE38922.1 - 0.0088 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 GtrA-like protein PDEase_II PF02112.10 EKE38922.1 - 0.35 9.7 4.4 1 8.2 1.3 2.3 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II TauE PF01925.14 EKE38923.1 - 4e-20 72.3 36.2 9.6e-11 41.5 18.0 2.6 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE YfhO PF09586.5 EKE38923.1 - 0.0032 15.5 0.0 0.0032 15.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial membrane protein YfhO Ctr PF04145.10 EKE38923.1 - 0.017 15.1 0.3 1.1 9.2 0.0 2.9 2 0 0 2 2 2 0 Ctr copper transporter family Synaptobrevin PF00957.16 EKE38923.1 - 0.15 11.7 0.2 0.15 11.7 0.2 3.1 3 0 0 3 3 3 0 Synaptobrevin Shisa PF13908.1 EKE38923.1 - 0.15 12.2 4.1 6 7.0 0.0 2.8 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF2500 PF10694.4 EKE38923.1 - 0.16 11.9 2.7 1.5 8.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2500) DUF4179 PF13786.1 EKE38923.1 - 0.19 11.9 0.1 0.19 11.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF4051 PF13260.1 EKE38923.1 - 1.1 8.6 0.0 1.1 8.6 0.0 3.1 2 1 0 2 2 1 0 Protein of unknown function (DUF4051) DUF4381 PF14316.1 EKE38923.1 - 2.1 8.4 11.5 2.5 8.1 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function (DUF4381) Sigma_reg_N PF13800.1 EKE38923.1 - 2.6 8.1 10.7 17 5.5 0.0 3.6 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1510 PF07423.6 EKE38923.1 - 3.1 7.0 10.9 0.27 10.5 3.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) MIG-14_Wnt-bd PF06664.7 EKE38925.1 - 1.2e-47 162.1 35.0 1.2e-47 162.1 24.3 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion adh_short PF00106.20 EKE38926.1 - 4e-22 78.9 0.0 6.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKE38926.1 - 2.5e-10 40.3 0.0 3.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKE38926.1 - 5.7e-09 35.7 0.1 8e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EKE38926.1 - 5.5e-08 32.8 0.0 9.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKE38926.1 - 0.00012 22.1 0.0 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EKE38926.1 - 0.0018 17.2 0.4 0.0025 16.7 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EKE38926.1 - 0.007 15.3 0.1 0.014 14.3 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein THF_DHG_CYH_C PF02882.14 EKE38926.1 - 0.044 12.8 0.9 0.095 11.7 0.2 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain E2F_TDP PF02319.15 EKE38926.1 - 0.1 12.2 0.0 0.33 10.5 0.0 1.9 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain RmlD_sub_bind PF04321.12 EKE38926.1 - 0.11 11.3 0.1 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain SBDS_C PF09377.5 EKE38927.1 - 1.8e-21 76.1 6.3 2.7e-21 75.5 4.3 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EKE38927.1 - 5.9e-17 61.2 1.2 5.9e-17 61.2 0.8 2.1 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SPO22 PF08631.5 EKE38927.1 - 0.022 13.8 5.5 0.028 13.5 3.8 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like DUF4111 PF13427.1 EKE38927.1 - 0.077 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) SBDS PF01172.13 EKE38928.1 - 5.6e-06 26.0 0.0 7.1e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PARG_cat PF05028.9 EKE38929.1 - 8.2e-64 215.9 3.2 1.2e-63 215.4 2.2 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF1810 PF08837.6 EKE38930.1 - 5.8e-41 139.3 0.0 8.8e-41 138.7 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1810) COX_ARM PF06481.9 EKE38930.1 - 0.1 12.2 0.1 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 COX Aromatic Rich Motif Auto_anti-p27 PF06677.7 EKE38931.1 - 4.8e-06 26.2 3.7 8.6e-06 25.4 2.6 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4611 PF15387.1 EKE38931.1 - 6.8 6.9 11.1 5.4 7.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) 60KD_IMP PF02096.15 EKE38932.1 - 0.25 11.0 2.9 0.55 9.8 2.0 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Arm PF00514.18 EKE38933.1 - 2.3e-06 27.2 0.0 0.004 16.9 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat La PF05383.12 EKE38933.1 - 0.0075 16.0 1.6 0.27 11.0 0.1 3.4 3 0 0 3 3 3 1 La domain DAGK_prokar PF01219.14 EKE38933.1 - 0.19 11.3 2.4 0.29 10.7 0.2 2.4 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase 14-3-3 PF00244.15 EKE38934.1 - 1.5e-110 367.8 9.8 1.7e-110 367.7 6.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EKE38934.1 - 0.0085 16.0 2.5 0.15 11.9 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF837 PF05769.6 EKE38934.1 - 0.029 13.9 1.2 1.6 8.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_8 PF13181.1 EKE38934.1 - 0.19 11.5 5.1 6.2 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKE38934.1 - 0.21 11.2 1.6 0.43 10.2 0.2 2.0 2 0 0 2 2 2 0 TPR repeat Pkinase PF00069.20 EKE38935.1 - 2.4e-58 197.3 0.2 2.8e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38935.1 - 5e-25 88.0 0.1 7.9e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE38935.1 - 1.4e-06 28.2 0.0 6.6e-06 26.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKE38935.1 - 0.0053 16.3 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EKE38935.1 - 0.0062 15.9 0.5 0.016 14.5 0.3 1.6 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 EKE38935.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RabGAP-TBC PF00566.13 EKE38937.1 - 4e-30 104.8 5.2 5.6e-30 104.4 3.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_32 PF13679.1 EKE38938.1 - 1.7e-23 82.8 1.0 3.4e-23 81.8 0.7 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE38938.1 - 7.3e-05 23.3 0.0 0.0002 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE38938.1 - 0.00042 20.0 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE38938.1 - 0.001 18.6 4.5 0.0011 18.5 0.9 2.7 3 1 0 3 3 3 1 Methyltransferase domain MetW PF07021.7 EKE38938.1 - 0.0018 17.7 0.1 0.0036 16.7 0.1 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF2777 PF10949.3 EKE38938.1 - 0.0044 16.7 0.3 0.0044 16.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2777) Methyltransf_11 PF08241.7 EKE38938.1 - 0.028 14.9 0.0 0.082 13.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.9 EKE38938.1 - 0.036 13.3 3.9 0.028 13.6 1.5 1.8 2 1 0 2 2 2 0 Methyltransferase TRM13 AAA_17 PF13207.1 EKE38938.1 - 0.049 14.4 0.3 0.43 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Methyltransf_25 PF13649.1 EKE38938.1 - 0.1 12.9 0.1 0.45 10.9 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EKE38938.1 - 0.16 12.4 0.1 1 9.8 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 EKE38940.1 - 4.6e-46 157.0 0.0 1.3e-45 155.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38940.1 - 4.4e-39 134.1 0.1 1e-38 132.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase SH2 PF00017.19 EKE38940.1 - 2.2e-08 33.7 0.1 4.7e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 SH2 domain YTH PF04146.10 EKE38940.1 - 0.013 15.0 0.4 0.025 14.1 0.2 1.6 1 1 0 1 1 1 0 YT521-B-like domain Kinase-like PF14531.1 EKE38940.1 - 0.029 13.3 0.0 0.098 11.5 0.0 1.9 1 1 1 2 2 2 0 Kinase-like RasGEF PF00617.14 EKE38941.1 - 3.3e-40 137.8 1.0 7.4e-40 136.6 0.7 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE38941.1 - 1.9e-06 27.9 1.2 0.00035 20.6 0.0 3.3 3 0 0 3 3 3 2 RasGEF N-terminal motif Pkinase PF00069.20 EKE38942.1 - 7.1e-55 185.9 0.0 9.9e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE38942.1 - 7.5e-45 153.0 0.0 1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EKE38942.1 - 0.0003 20.2 0.2 0.0005 19.4 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DnaJ PF00226.26 EKE38944.1 - 1.3e-28 98.4 4.3 4.5e-28 96.7 1.7 2.2 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 EKE38944.1 - 2.1e-17 62.7 7.9 1.2e-16 60.3 0.2 2.9 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKE38944.1 - 8.8e-16 57.7 19.5 8.8e-16 57.7 13.5 2.0 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EKE38944.1 - 0.063 12.9 9.9 1.1 8.9 0.7 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ank_2 PF12796.2 EKE38945.1 - 3.4e-29 101.0 12.3 2.9e-13 49.9 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE38945.1 - 1.3e-28 97.3 2.5 5.8e-07 28.9 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 EKE38945.1 - 1.8e-24 83.3 3.7 3.2e-05 23.7 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EKE38945.1 - 6.7e-22 77.4 6.8 1.9e-07 31.4 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE38945.1 - 5.4e-17 61.4 5.3 6.4e-07 29.4 0.1 4.1 3 2 1 4 4 4 3 Ankyrin repeats (many copies) H_lectin PF09458.5 EKE38945.1 - 0.0004 19.9 0.1 0.0011 18.5 0.1 1.7 1 0 0 1 1 1 1 H-type lectin domain DUF1353 PF07087.6 EKE38945.1 - 0.085 12.3 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Ras_bdg_2 PF14847.1 EKE38945.1 - 0.39 10.6 2.9 9.7 6.1 0.2 3.2 3 0 0 3 3 3 0 Ras-binding domain of Byr2 Rap_GAP PF02145.10 EKE38946.1 - 2.4e-43 147.7 0.6 2.8e-43 147.4 0.4 1.0 1 0 0 1 1 1 1 Rap/ran-GAP TRAM_LAG1_CLN8 PF03798.11 EKE38948.1 - 9.5e-29 100.3 15.6 9.5e-29 100.3 10.8 1.7 2 0 0 2 2 2 1 TLC domain SIR2 PF02146.12 EKE38949.1 - 1.9e-50 171.0 0.0 4.2e-50 169.9 0.0 1.6 2 0 0 2 2 2 1 Sir2 family zf-UBP PF02148.14 EKE38949.1 - 2e-18 66.2 15.1 2e-18 66.2 10.5 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein LSM PF01423.17 EKE38950.1 - 3.6e-18 64.8 0.1 4.2e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain FCH PF00611.18 EKE38951.1 - 0.00065 19.8 1.5 0.0019 18.3 0.0 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SlyX PF04102.7 EKE38951.1 - 0.6 10.5 7.5 1.1 9.7 1.1 4.0 4 0 0 4 4 4 0 SlyX L31 PF09784.4 EKE38951.1 - 9.4 6.3 7.7 1 9.4 0.4 2.9 2 1 2 4 4 4 0 Mitochondrial ribosomal protein L31 LRR_5 PF13306.1 EKE38952.1 - 5.4e-181 592.0 104.2 2.4e-30 104.9 8.0 9.7 5 3 3 9 9 9 9 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38952.1 - 1.9e-66 219.7 23.8 8.5e-08 31.8 0.3 15.1 6 5 11 18 18 18 16 Leucine rich repeat DUF285 PF03382.9 EKE38952.1 - 0.00053 19.5 0.1 0.56 9.7 0.0 4.7 3 2 0 3 3 3 1 Mycoplasma protein of unknown function, DUF285 LRR_4 PF12799.2 EKE38952.1 - 0.028 14.0 6.6 2.8 7.6 0.0 6.6 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) YhhN PF07947.9 EKE38953.1 - 9.9e-25 86.9 18.9 1.4e-24 86.4 13.1 1.2 1 0 0 1 1 1 1 YhhN-like protein PP2C PF00481.16 EKE38955.1 - 2.3e-46 158.2 0.1 3.4e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EKE38955.1 - 1.4e-29 101.2 77.1 3.2e-08 32.9 5.7 10.8 2 2 9 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE38955.1 - 2.3e-25 88.1 82.9 2.4e-08 33.5 7.4 8.5 1 1 11 12 12 12 12 Leucine rich repeat LRR_1 PF00560.28 EKE38955.1 - 2.2e-15 54.3 57.9 0.01 15.7 1.1 15.0 14 2 0 14 14 14 6 Leucine Rich Repeat LRR_7 PF13504.1 EKE38955.1 - 2.4e-05 23.8 53.9 0.16 12.2 0.2 13.0 14 0 0 14 14 14 4 Leucine rich repeat PP2C_2 PF13672.1 EKE38955.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C LRR_9 PF14580.1 EKE38955.1 - 0.18 11.3 27.0 3.4 7.2 1.9 5.1 1 1 4 5 5 5 0 Leucine-rich repeat PFK PF00365.15 EKE38956.1 - 5.3e-44 150.2 0.3 7e-44 149.8 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 EKE38956.1 - 0.02 13.6 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase CLU PF13236.1 EKE38956.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria BLOC1_2 PF10046.4 EKE38957.1 - 0.013 15.6 0.8 0.053 13.6 0.6 2.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAP2 PF01569.16 EKE38958.1 - 3.7e-21 75.1 3.8 3.7e-21 75.1 2.7 2.9 3 1 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EKE38958.1 - 0.0046 16.4 1.7 0.0046 16.4 1.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily V-SNARE_C PF12352.3 EKE38959.1 - 2e-06 27.7 3.4 2.5e-06 27.4 2.4 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.13 EKE38959.1 - 0.02 12.9 3.1 0.022 12.8 2.1 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF1640 PF07798.6 EKE38959.1 - 0.029 14.4 0.5 0.034 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) UPF0233 PF06781.7 EKE38959.1 - 0.061 12.9 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Tropomyosin_1 PF12718.2 EKE38959.1 - 0.08 12.7 0.3 0.094 12.5 0.2 1.1 1 0 0 1 1 1 0 Tropomyosin like Pex24p PF06398.6 EKE38959.1 - 0.083 11.6 0.7 0.086 11.6 0.5 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Synaptobrevin PF00957.16 EKE38959.1 - 0.086 12.4 1.6 0.11 12.1 1.1 1.3 1 1 0 1 1 1 0 Synaptobrevin Metallophos PF00149.23 EKE38960.1 - 8.6e-11 41.6 0.2 1.4e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3584 PF12128.3 EKE38961.1 - 0.71 7.1 53.2 2.4 5.3 36.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Pdase_C33_assoc PF14756.1 EKE38961.1 - 9.2 5.9 7.2 0.95 9.1 1.0 2.1 2 0 0 2 2 2 0 Peptidase_C33-associated domain Lipid_DES PF08557.5 EKE38962.1 - 0.13 11.5 2.3 2.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) TLD PF07534.11 EKE38963.1 - 0.07 13.1 0.4 0.073 13.0 0.3 1.0 1 0 0 1 1 1 0 TLD DUF3883 PF13020.1 EKE38963.1 - 0.21 11.3 0.8 2.7 7.8 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3883) Syja_N PF02383.13 EKE38965.1 - 2.7e-65 220.2 4.0 2.7e-65 220.2 2.7 2.8 2 2 1 3 3 3 1 SacI homology domain SLIDE PF09111.5 EKE38965.1 - 0.0028 17.3 2.2 0.69 9.6 0.2 2.8 2 0 0 2 2 2 2 SLIDE DSPc PF00782.15 EKE38967.1 - 2.7e-35 120.8 0.3 4e-35 120.2 0.2 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE38967.1 - 6.8e-07 28.8 0.0 8.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EKE38967.1 - 0.00012 21.0 0.2 0.00027 19.9 0.1 1.5 1 1 1 2 2 2 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase2 PF03162.8 EKE38967.1 - 0.00013 21.3 0.3 0.00017 20.9 0.2 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKE38967.1 - 0.0023 17.9 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EKE38967.1 - 0.0024 18.1 0.0 1.2 9.3 0.0 2.3 1 1 1 2 2 2 2 Tyrosine phosphatase family CDKN3 PF05706.7 EKE38967.1 - 0.048 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Sec5 PF15469.1 EKE38968.1 - 1.6e-37 128.9 5.4 1.6e-37 128.9 3.8 4.9 4 2 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.6 EKE38968.1 - 3.3e-06 26.8 5.6 5.1e-05 23.0 0.3 4.5 3 1 1 4 4 4 1 Vps51/Vps67 Ras PF00071.17 EKE38969.1 - 5.9e-60 201.3 0.1 7e-60 201.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE38969.1 - 1.6e-16 60.9 0.0 2.5e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38969.1 - 2.3e-14 53.0 0.1 2.8e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE38969.1 - 2.5e-05 24.1 0.1 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE38969.1 - 3.3e-05 23.1 0.1 3.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EKE38969.1 - 4.4e-05 22.7 0.1 0.071 12.3 0.1 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B SRPRB PF09439.5 EKE38969.1 - 0.00014 21.1 0.0 0.00026 20.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE38969.1 - 0.00033 20.1 0.2 0.0011 18.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKE38969.1 - 0.00058 19.3 0.1 0.0013 18.2 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE38969.1 - 0.00063 18.9 0.2 0.0042 16.2 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKE38969.1 - 0.0026 17.9 0.4 0.023 14.8 0.0 2.3 2 1 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EKE38969.1 - 0.0036 16.9 0.1 0.0097 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE38969.1 - 0.006 16.3 0.2 0.018 14.7 0.1 1.7 1 1 1 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 EKE38969.1 - 0.015 15.0 0.1 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.13 EKE38969.1 - 0.024 13.6 0.1 0.052 12.5 0.0 1.5 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 EKE38969.1 - 0.03 13.0 3.7 1 7.9 0.4 2.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 EKE38969.1 - 0.035 14.0 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EKE38969.1 - 0.064 13.5 0.9 0.13 12.5 0.6 1.8 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EKE38969.1 - 0.073 12.9 0.2 0.21 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EKE38969.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.4 EKE38969.1 - 0.11 11.3 0.2 0.22 10.4 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.1 EKE38969.1 - 0.16 11.3 0.2 0.69 9.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EKE38970.1 - 4.1e-52 175.9 0.1 4.6e-52 175.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EKE38970.1 - 1.2e-09 37.7 0.1 1.3e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EKE38970.1 - 1.5e-08 33.8 0.1 2.5e-08 33.0 0.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EKE38970.1 - 1.6e-07 30.7 0.1 1.6e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EKE38970.1 - 1.4e-05 25.5 0.0 2.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EKE38970.1 - 1.8e-05 24.0 0.0 2.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE38970.1 - 0.017 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Metallophos PF00149.23 EKE38971.1 - 7.9e-26 90.6 0.7 1.4e-25 89.9 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3355 PF11835.3 EKE38971.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) IFNGR1 PF07140.6 EKE38971.1 - 0.047 13.4 2.2 0.18 11.5 1.2 2.1 1 1 0 1 1 1 0 Interferon gamma receptor (IFNGR1) NT-C2 PF10358.4 EKE38972.1 - 1.7e-12 47.0 5.1 2.4e-12 46.5 2.3 2.1 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EKE38972.1 - 0.0029 17.4 0.2 0.027 14.3 0.1 2.3 1 1 1 2 2 2 1 DIL domain Aa_trans PF01490.13 EKE38973.1 - 4.7e-19 68.1 34.9 4.7e-19 68.1 24.2 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EKE38973.1 - 3.3e-08 32.5 45.0 6.4e-08 31.5 29.4 2.3 2 1 0 2 2 2 1 Amino acid permease Ribosomal_L29e PF01779.12 EKE38975.1 - 5.2e-16 58.2 7.9 8.7e-16 57.5 5.5 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Gtr1_RagA PF04670.7 EKE38976.1 - 6.3e-33 113.8 2.6 8.7e-33 113.3 1.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE38976.1 - 1.9e-06 27.7 0.1 7e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EKE38976.1 - 0.00017 22.0 0.1 0.0004 20.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE38976.1 - 0.00019 20.7 0.3 0.00034 19.9 0.1 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 EKE38976.1 - 0.0092 15.2 0.2 0.022 14.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B DS PF01916.12 EKE38978.1 - 4e-102 341.3 0.0 4.6e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF3933 PF13069.1 EKE38979.1 - 0.0082 15.8 0.2 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3933) Lpp-LpqN PF10738.4 EKE38979.1 - 0.087 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Probable lipoprotein LpqN Metallophos PF00149.23 EKE38980.1 - 3.3e-41 140.9 0.0 4.4e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EKE38981.1 - 2e-28 97.1 10.6 1.7e-05 24.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EKE38981.1 - 0.0017 17.1 2.3 0.21 10.2 0.3 2.9 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_3 PF13570.1 EKE38981.1 - 0.02 15.1 0.0 14 6.1 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain Apc4_WD40 PF12894.2 EKE38981.1 - 0.031 13.7 0.0 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.6 EKE38981.1 - 0.036 13.2 1.8 0.9 8.7 0.0 3.1 2 1 1 3 3 3 0 TUP1-like enhancer of split DUF2138 PF09909.4 EKE38981.1 - 0.17 9.9 0.0 0.26 9.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Alba PF01918.16 EKE38982.1 - 0.00028 20.4 0.4 0.0009 18.7 0.0 2.1 3 0 0 3 3 3 1 Alba Rpp20 PF12328.3 EKE38982.1 - 0.48 10.0 0.0 0.48 10.0 0.0 2.5 2 1 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Aminotran_1_2 PF00155.16 EKE38983.1 - 2e-44 152.0 0.0 2.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EKE38983.1 - 1.8e-05 23.6 0.0 2.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EKE38983.1 - 0.00098 17.4 0.0 0.0015 16.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EKE38983.1 - 0.043 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ICMT PF04140.9 EKE38985.1 - 8.9e-27 93.1 0.5 8.9e-27 93.1 0.4 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EKE38985.1 - 7.4e-09 35.6 1.8 7.4e-09 35.6 1.2 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF3169 PF11368.3 EKE38985.1 - 0.02 14.0 7.1 1.2 8.3 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF1295 PF06966.7 EKE38985.1 - 0.38 9.9 5.5 0.22 10.8 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) UPF0118 PF01594.11 EKE38986.1 - 2.4e-15 56.3 37.7 3.1e-15 56.0 26.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 Ras PF00071.17 EKE38987.1 - 0.0097 15.3 0.4 0.018 14.4 0.3 1.5 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EKE38987.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain U79_P34 PF03064.11 EKE38987.1 - 0.05 13.1 0.3 0.058 12.9 0.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Asn_synthase PF00733.16 EKE38987.1 - 0.058 12.8 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Asparagine synthase PI3Ka PF00613.15 EKE38988.1 - 3.4e-51 173.0 0.1 6.7e-51 172.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EKE38988.1 - 3.7e-13 49.4 0.0 7.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.13 EKE38988.1 - 1.4e-09 37.8 0.0 5.3e-09 35.9 0.0 2.1 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 EKE38988.1 - 1.5e-07 31.2 0.2 3.2e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PRESAN PF09687.5 EKE38989.1 - 0.013 15.5 0.1 0.014 15.4 0.1 1.0 1 0 0 1 1 1 0 Plasmodium RESA N-terminal RhoGEF PF00621.15 EKE38990.1 - 3.9e-17 62.6 9.8 3.9e-17 62.6 6.8 1.7 2 0 0 2 2 2 1 RhoGEF domain IQ PF00612.22 EKE38990.1 - 0.0061 16.0 0.2 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif PAP_fibrillin PF04755.7 EKE38990.1 - 0.0097 15.6 2.8 0.2 11.3 0.1 2.4 2 0 0 2 2 2 2 PAP_fibrillin SRP19 PF01922.12 EKE38992.1 - 1.8e-23 82.9 0.8 2.3e-23 82.6 0.5 1.1 1 0 0 1 1 1 1 SRP19 protein eIF-6 PF01912.13 EKE38993.1 - 6.9e-76 253.7 0.2 8.5e-76 253.4 0.1 1.1 1 0 0 1 1 1 1 eIF-6 family DUF1272 PF06906.6 EKE38994.1 - 0.19 11.5 10.7 0.049 13.4 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Prenyltrans PF00432.16 EKE38995.1 - 1.5e-45 152.4 4.5 7.8e-16 57.3 2.0 4.8 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKE38995.1 - 2.8e-27 95.3 0.0 2.1e-14 53.8 0.0 2.9 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EKE38995.1 - 4.6e-10 39.4 0.0 3.6e-05 23.7 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 EKE38995.1 - 0.006 15.8 0.1 7.9 5.6 0.0 3.3 2 1 1 3 3 3 2 A-macroglobulin complement component Pep3_Vps18 PF05131.9 EKE38996.1 - 0.0087 15.5 0.3 0.054 12.9 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family zf-RING_2 PF13639.1 EKE38996.1 - 0.024 14.4 5.7 0.083 12.7 3.9 2.0 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EKE38996.1 - 4.9 6.9 10.7 25 4.6 7.4 2.3 1 1 0 1 1 1 0 zinc-RING finger domain UDG PF03167.14 EKE38997.1 - 2e-09 37.0 0.0 2.4e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily LRR_5 PF13306.1 EKE38998.1 - 6.5e-56 187.5 31.8 3.9e-27 94.4 7.1 4.0 1 1 3 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE38998.1 - 6.8e-25 86.5 0.9 1.5e-06 27.8 0.0 5.4 2 2 3 5 5 5 5 Leucine rich repeat HEAT PF02985.17 EKE38999.1 - 5.6e-07 29.1 0.1 0.049 13.7 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat CLASP_N PF12348.3 EKE38999.1 - 3.5e-05 23.2 1.0 0.0034 16.7 0.1 2.5 1 1 1 2 2 2 2 CLASP N terminal Pkinase_Tyr PF07714.12 EKE38999.1 - 0.0021 17.1 0.1 0.0087 15.1 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 EKE38999.1 - 0.032 13.3 0.1 0.032 13.3 0.1 2.1 2 1 1 3 3 3 0 Protein kinase domain HEAT_EZ PF13513.1 EKE38999.1 - 0.041 14.3 0.0 14 6.3 0.0 3.4 3 1 0 3 3 3 0 HEAT-like repeat Rabaptin PF03528.10 EKE38999.1 - 1.8 8.5 11.9 0.21 11.5 1.3 3.2 3 0 0 3 3 3 0 Rabaptin Ras PF00071.17 EKE39000.1 - 1.2e-61 206.7 1.0 1.4e-61 206.5 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39000.1 - 8.7e-18 64.9 0.0 1.6e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39000.1 - 2.2e-16 59.5 0.3 2.7e-16 59.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39000.1 - 9.6e-06 24.8 0.5 1.2e-05 24.5 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE39000.1 - 0.0001 22.2 0.1 0.00013 21.8 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE39000.1 - 0.00016 21.1 0.3 0.00025 20.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE39000.1 - 0.0015 17.7 0.2 0.0017 17.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit UPF0175 PF03683.8 EKE39000.1 - 0.033 13.6 0.4 0.059 12.8 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) DUF258 PF03193.11 EKE39000.1 - 0.047 12.8 0.1 0.14 11.2 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ank PF00023.25 EKE39000.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeat RhoGAP PF00620.22 EKE39001.1 - 1.6e-34 118.7 0.0 2.8e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Fib_alpha PF08702.5 EKE39001.1 - 0.0098 16.0 1.1 0.027 14.5 0.8 1.7 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EKE39001.1 - 0.34 10.7 3.6 0.71 9.6 2.5 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TLD PF07534.11 EKE39002.1 - 8.7e-06 25.7 2.5 0.0012 18.8 0.0 3.0 2 1 0 2 2 2 2 TLD Apolipoprotein PF01442.13 EKE39002.1 - 0.0076 15.7 9.2 0.13 11.7 6.3 2.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.7 EKE39002.1 - 7.9 6.8 25.1 1.5e+04 -11.4 17.4 4.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Alpha_kinase PF02816.13 EKE39003.1 - 1.8e-35 122.3 0.1 3.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-kinase family SH3_2 PF07653.12 EKE39003.1 - 2.6e-18 65.2 0.0 2.3e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 EKE39003.1 - 3.2e-15 55.4 0.0 2.6e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EKE39003.1 - 2.8e-13 49.0 0.0 1.5e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Glycoprotein_G PF00802.14 EKE39004.1 - 2.7 7.0 14.7 0.075 12.1 2.7 2.2 1 1 1 2 2 2 0 Pneumovirus attachment glycoprotein G Ank_2 PF12796.2 EKE39005.1 - 7.4e-13 48.6 1.0 1e-05 25.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE39005.1 - 3.3e-12 46.2 0.2 1.6e-06 28.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EKE39005.1 - 2.6e-10 39.5 4.0 1.5e-07 30.8 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EKE39005.1 - 3.9e-08 32.7 1.0 6.2e-05 22.8 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EKE39005.1 - 1e-07 32.2 3.7 0.0032 17.9 0.1 3.5 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Thioredoxin PF00085.15 EKE39006.1 - 1e-11 44.4 0.0 1.1e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKE39006.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_6 PF13848.1 EKE39006.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain PIGA PF08288.7 EKE39007.1 - 2.5e-32 111.0 0.2 1e-31 109.1 0.2 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EKE39007.1 - 1.2e-23 83.4 0.0 1.9e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EKE39007.1 - 1e-13 51.7 0.0 1.4e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EKE39007.1 - 2.2e-11 43.8 2.4 2.9e-11 43.4 0.5 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EKE39007.1 - 4.7e-08 33.2 0.0 1.3e-07 31.8 0.0 1.7 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EKE39007.1 - 6.9e-05 22.6 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EKE39007.1 - 0.018 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 EF-hand_1 PF00036.27 EKE39008.1 - 1.1e-11 43.0 4.0 5.6e-06 25.2 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EKE39008.1 - 7.3e-11 41.5 6.5 0.00014 21.4 0.3 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EKE39008.1 - 8.8e-11 41.7 1.7 0.00026 21.0 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE39008.1 - 9.1e-11 40.7 4.2 1e-05 24.9 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EKE39008.1 - 2.2e-06 26.7 0.9 0.00077 18.6 0.2 2.4 2 0 0 2 2 2 2 EF hand DUF4476 PF14771.1 EKE39008.1 - 0.0082 16.1 0.8 0.35 10.9 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) APG6 PF04111.7 EKE39009.1 - 3e-08 33.1 19.7 2.6e-07 29.9 13.7 2.0 1 1 0 1 1 1 1 Autophagy protein Apg6 DUF1357 PF07094.6 EKE39009.1 - 0.0025 17.2 5.4 0.0053 16.2 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1357) DUF2959 PF11172.3 EKE39009.1 - 0.047 13.4 3.8 0.085 12.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF1125 PF06563.6 EKE39009.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1125) CALCOCO1 PF07888.6 EKE39009.1 - 0.14 10.4 6.1 0.21 9.8 4.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like START PF01852.14 EKE39010.1 - 2.7e-12 46.4 0.1 3.8e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 START domain DUF1104 PF06518.6 EKE39010.1 - 0.073 13.2 1.8 0.69 10.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) Cpn60_TCP1 PF00118.19 EKE39011.1 - 2.6e-107 359.4 12.1 3e-107 359.2 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Clathrin_bdg PF15045.1 EKE39011.1 - 0.13 11.8 0.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking pRN1_helical PF13010.1 EKE39012.1 - 0.088 12.4 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Primase helical domain Glycogen_syn PF05693.8 EKE39012.1 - 0.1 10.8 0.0 0.12 10.6 0.0 1.0 1 0 0 1 1 1 0 Glycogen synthase TLD PF07534.11 EKE39013.1 - 3.3e-06 27.1 0.4 3.3e-06 27.1 0.3 1.9 2 0 0 2 2 2 1 TLD MFS_1 PF07690.11 EKE39014.1 - 1.4e-23 83.1 5.0 1.4e-23 83.1 3.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S49_N PF08496.5 EKE39014.1 - 1.8 8.3 9.1 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ras PF00071.17 EKE39015.1 - 0.00018 20.9 0.1 0.00019 20.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39015.1 - 0.00061 20.2 0.0 0.00069 20.1 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 EKE39015.1 - 0.066 12.8 0.0 0.066 12.8 0.0 1.0 1 0 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 EKE39015.1 - 0.09 12.0 0.0 0.092 12.0 0.0 1.0 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.17 EKE39015.1 - 0.091 12.9 0.0 0.099 12.8 0.0 1.1 1 0 0 1 1 1 0 RNA helicase Arf PF00025.16 EKE39015.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE39015.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 EKE39016.1 - 1.3e-13 50.6 0.0 1.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39016.1 - 0.00079 19.9 0.1 0.0024 18.3 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein Isy1 PF06246.7 EKE39016.1 - 0.0063 15.9 0.1 0.0079 15.6 0.0 1.1 1 0 0 1 1 1 1 Isy1-like splicing family DUF3391 PF11871.3 EKE39016.1 - 0.12 12.6 0.5 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) RhoGAP PF00620.22 EKE39017.1 - 2.3e-12 46.7 0.0 3.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Mem_trans PF03547.13 EKE39018.1 - 3e-44 150.9 3.1 5.3e-43 146.7 2.1 2.0 1 1 0 1 1 1 1 Membrane transport protein Mitofilin PF09731.4 EKE39018.1 - 0.37 9.4 20.6 0.47 9.0 14.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4551 PF15087.1 EKE39018.1 - 2.5 6.3 11.4 4.3 5.5 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rho_RNA_bind PF07497.7 EKE39020.1 - 0.091 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Ricin_B_lectin PF00652.17 EKE39021.1 - 6.4e-08 32.6 0.0 1.4e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EKE39021.1 - 1.5e-06 28.5 0.0 4.3e-06 27.0 0.0 1.6 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF4355 PF14265.1 EKE39022.1 - 0.067 13.1 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF4284 PF14112.1 EKE39022.1 - 0.19 12.2 5.8 0.29 11.6 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4284) TPR_11 PF13414.1 EKE39023.1 - 8e-24 83.0 9.5 1.1e-11 44.2 0.5 4.4 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 EKE39023.1 - 1.2e-16 59.5 10.1 1.7e-06 27.3 0.4 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EKE39023.1 - 4.9e-15 54.1 10.6 0.00013 21.6 0.1 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EKE39023.1 - 2.4e-10 40.4 4.4 3.1e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EKE39023.1 - 1e-07 32.2 1.2 1.9 8.8 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE39023.1 - 5.4e-07 29.4 4.6 1.2 9.1 0.0 4.5 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE39023.1 - 8.3e-06 26.3 0.0 0.94 10.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKE39023.1 - 4.6e-05 22.9 1.2 2.6 8.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKE39023.1 - 5.4e-05 23.4 0.0 1.8 9.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKE39023.1 - 7.3e-05 22.6 8.6 0.0017 18.3 0.1 4.4 4 1 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKE39023.1 - 0.00026 20.7 2.4 0.014 15.3 0.0 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EKE39023.1 - 0.0043 16.7 17.1 0.76 9.7 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKE39023.1 - 0.025 15.0 11.1 5 7.8 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EKE39023.1 - 0.056 12.9 5.2 3.1 7.1 1.8 3.0 2 1 0 2 2 2 0 Foie gras liver health family 1 TPR_9 PF13371.1 EKE39023.1 - 0.08 12.8 0.0 6.5 6.6 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EKE39023.1 - 1.1 9.0 9.1 3 7.7 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF384 PF04064.8 EKE39023.1 - 4.1 7.0 6.2 0.84 9.2 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF384) Sigma_reg_N PF13800.1 EKE39024.1 - 2.8 8.0 9.9 1.1 9.3 0.5 3.1 1 1 2 3 3 3 0 Sigma factor regulator N-terminal LIM PF00412.17 EKE39025.1 - 2.1e-09 37.3 6.2 4e-09 36.3 4.3 1.5 1 0 0 1 1 1 1 LIM domain CENP-Q PF13094.1 EKE39025.1 - 0.00032 20.7 0.8 0.00044 20.3 0.5 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-met PF12874.2 EKE39025.1 - 0.041 14.0 0.5 0.041 14.0 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DNA_ligase_ZBD PF03119.11 EKE39025.1 - 0.045 13.4 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-TFIIB PF13453.1 EKE39025.1 - 0.075 12.2 0.8 3.6 6.8 0.0 2.5 1 1 1 2 2 2 0 Transcription factor zinc-finger C1_2 PF03107.11 EKE39025.1 - 0.1 12.7 5.4 0.16 12.1 0.9 2.9 3 0 0 3 3 3 0 C1 domain DUF3579 PF12112.3 EKE39025.1 - 0.1 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Zn_Tnp_IS1595 PF12760.2 EKE39025.1 - 0.11 12.3 4.3 0.094 12.5 1.6 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EKE39025.1 - 0.17 11.5 2.8 0.33 10.6 1.5 1.9 1 1 0 1 1 1 0 Putative transposase DNA-binding domain YojJ PF10372.4 EKE39025.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.1 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus FdhE PF04216.7 EKE39025.1 - 0.24 11.0 2.1 0.7 9.5 1.1 1.7 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation DUF4428 PF14471.1 EKE39025.1 - 0.25 11.1 4.9 0.64 9.8 2.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) RRN7 PF11781.3 EKE39025.1 - 0.77 9.3 4.1 1.6 8.3 0.7 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Sgf11 PF08209.6 EKE39025.1 - 1.4 8.2 5.1 1.8 7.9 0.7 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) LIM PF00412.17 EKE39026.1 - 9.8e-12 44.7 28.2 1.4e-07 31.4 10.2 3.7 3 1 0 3 3 3 2 LIM domain zf-ribbon_3 PF13248.1 EKE39026.1 - 2.6e-07 29.6 2.9 2.6e-07 29.6 2.0 3.8 2 1 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EKE39026.1 - 2.5e-06 26.7 4.1 2.5e-06 26.7 2.8 3.9 2 1 1 3 3 3 1 zinc-ribbon domain DZR PF12773.2 EKE39026.1 - 0.00036 20.2 0.7 0.00036 20.2 0.5 3.9 2 1 1 3 3 3 1 Double zinc ribbon UPF0547 PF10571.4 EKE39026.1 - 0.036 13.7 1.8 0.036 13.7 1.3 3.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 C1_1 PF00130.17 EKE39026.1 - 0.094 12.4 0.6 0.094 12.4 0.4 4.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_PEP_C PF04513.7 EKE39027.1 - 0.14 11.9 3.7 0.18 11.6 1.1 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EKE39027.1 - 0.28 11.4 11.0 2 8.7 1.0 4.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF489 PF04356.7 EKE39027.1 - 1.2 8.6 10.0 0.28 10.7 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF489) CCDC155 PF14662.1 EKE39027.1 - 2.1 7.9 38.6 0.086 12.4 11.4 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF948 PF06103.6 EKE39027.1 - 3.9 7.4 13.5 0.28 11.0 3.1 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CN_hydrolase PF00795.17 EKE39029.1 - 3.4e-12 46.0 0.0 7e-12 45.0 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Ribosomal_L30_N PF08079.7 EKE39030.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain YhhN PF07947.9 EKE39031.1 - 1.4e-19 70.2 20.0 1.4e-19 70.2 13.9 1.3 1 1 0 1 1 1 1 YhhN-like protein Cortexin PF11057.3 EKE39031.1 - 0.014 14.9 0.2 0.047 13.2 0.1 2.0 1 0 0 1 1 1 0 Cortexin of kidney Ank_2 PF12796.2 EKE39032.1 - 1e-26 93.0 9.6 4e-12 46.3 0.9 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE39032.1 - 2.8e-25 87.7 7.1 5.7e-11 42.2 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EKE39032.1 - 1.7e-24 84.3 5.9 1.1e-06 28.0 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EKE39032.1 - 3.9e-24 84.5 8.3 4.3e-09 36.6 1.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE39032.1 - 4e-21 73.0 3.6 1.2e-05 25.0 0.1 4.9 4 0 0 4 4 4 3 Ankyrin repeat Metallophos_2 PF12850.2 EKE39033.1 - 3e-08 33.6 0.4 4.3e-08 33.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EKE39033.1 - 4.7e-05 22.8 5.8 0.00022 20.6 4.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.2 EKE39034.1 - 2.6e-07 30.2 0.1 1.1e-06 28.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EKE39034.1 - 0.00043 20.0 0.0 0.041 13.7 0.0 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat F-box PF00646.28 EKE39034.1 - 0.00046 19.7 0.7 0.0018 17.9 0.5 2.0 2 0 0 2 2 2 1 F-box domain PQQ_3 PF13570.1 EKE39034.1 - 0.0057 16.8 0.5 0.49 10.7 0.0 3.0 3 0 0 3 3 3 1 PQQ-like domain PRANC PF09372.5 EKE39034.1 - 0.17 11.8 4.0 0.13 12.2 0.6 2.5 2 0 0 2 2 2 0 PRANC domain RabGAP-TBC PF00566.13 EKE39035.1 - 8e-42 143.1 9.2 1.4e-41 142.3 6.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HDV_ag PF01517.13 EKE39035.1 - 0.092 12.4 1.4 0.12 12.0 0.6 1.4 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen RhoGAP PF00620.22 EKE39036.1 - 1.9e-23 82.7 0.0 4.9e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain UBA_4 PF14555.1 EKE39037.1 - 9.2e-12 44.2 0.1 1.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EKE39037.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EKE39037.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 UBX domain UBA PF00627.26 EKE39037.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain zf-C3HC4_3 PF13920.1 EKE39038.1 - 1e-09 37.8 8.7 1.6e-09 37.2 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE39038.1 - 5.6e-08 32.4 10.9 1e-07 31.6 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKE39038.1 - 3e-07 30.0 11.5 3e-07 30.0 8.0 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE39038.1 - 3.3e-07 30.2 12.1 5.7e-07 29.4 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE39038.1 - 9e-07 28.4 11.1 9e-07 28.4 7.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE39038.1 - 7.7e-06 25.6 11.2 1.3e-05 24.9 7.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EKE39038.1 - 0.00022 20.6 4.1 0.00041 19.8 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EKE39038.1 - 0.00026 20.6 5.9 0.00062 19.4 4.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EKE39038.1 - 0.0083 15.8 5.0 0.017 14.8 3.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-UDP PF14569.1 EKE39038.1 - 0.079 12.7 3.8 0.15 11.8 2.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Fra10Ac1 PF09725.4 EKE39038.1 - 0.086 12.9 1.2 0.15 12.1 0.8 1.3 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 zf-RING_4 PF14570.1 EKE39038.1 - 0.17 11.4 9.7 0.42 10.2 6.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EKE39038.1 - 0.44 10.6 11.8 0.45 10.6 6.5 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EKE39038.1 - 0.56 9.7 9.4 1.8 8.1 6.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.20 EKE39039.1 - 2.5e-63 213.6 0.1 3.8e-44 150.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39039.1 - 2.3e-29 102.2 0.0 3.4e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKE39039.1 - 4.2e-10 39.5 0.0 1.4e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EKE39039.1 - 8.7e-06 24.9 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE39039.1 - 0.0018 18.0 0.0 0.0051 16.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EKE39039.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PyrI_C PF02748.10 EKE39040.1 - 0.00031 20.0 0.6 0.00081 18.7 0.4 1.8 1 1 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain Atg14 PF10186.4 EKE39040.1 - 0.0017 17.3 13.5 0.0028 16.6 9.3 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EKE39040.1 - 0.0049 16.4 10.9 0.0054 16.3 7.6 1.0 1 0 0 1 1 1 1 IncA protein ATG16 PF08614.6 EKE39040.1 - 0.0064 16.3 9.8 0.0077 16.0 6.8 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 EKE39040.1 - 0.017 14.9 4.3 0.023 14.5 3.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.4 EKE39040.1 - 0.054 12.2 15.7 0.066 11.9 10.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RNA_pol_Rpb5_C PF01191.14 EKE39040.1 - 0.084 12.4 3.8 0.18 11.4 2.6 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Tup_N PF08581.5 EKE39040.1 - 0.12 12.5 15.1 1.4 9.1 2.6 2.2 1 1 1 2 2 2 0 Tup N-terminal Fib_alpha PF08702.5 EKE39040.1 - 0.22 11.6 15.8 0.33 11.0 11.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EKE39040.1 - 0.73 9.6 9.7 3.3 7.5 6.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 EKE39040.1 - 0.9 9.4 17.6 1.2 9.0 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.2 EKE39040.1 - 1.7 8.4 15.9 0.9 9.3 4.7 2.1 1 1 1 2 2 2 0 Tropomyosin like AAA_13 PF13166.1 EKE39040.1 - 1.8 6.8 19.7 3.4 5.9 13.7 1.4 1 1 0 1 1 1 0 AAA domain YlqD PF11068.3 EKE39040.1 - 2.6 8.0 17.7 0.41 10.6 7.3 2.0 1 1 0 1 1 1 0 YlqD protein Lectin_N PF03954.9 EKE39040.1 - 4.2 6.7 9.5 4.7 6.6 3.5 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1359 PF07097.6 EKE39040.1 - 5.1 7.1 12.3 6.9 6.7 2.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1359) zf-C4H2 PF10146.4 EKE39040.1 - 7.7 6.4 13.0 9.3 6.1 9.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein UPF0449 PF15136.1 EKE39040.1 - 8.2 6.7 10.3 1.9 8.7 2.4 2.4 2 1 1 3 3 2 0 Uncharacterised protein family UPF0449 NAP PF00956.13 EKE39041.1 - 1.7e-11 43.6 15.5 9.4e-10 38.0 10.8 2.2 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) RIIa PF02197.12 EKE39041.1 - 0.035 13.5 0.1 0.086 12.2 0.1 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit YL1 PF05764.8 EKE39042.1 - 2.6 7.6 5.3 2.9 7.4 3.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_C1 PF00112.18 EKE39043.1 - 4.3e-72 242.5 4.7 6.3e-72 241.9 3.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE39043.1 - 1.6e-05 25.0 3.0 2.9e-05 24.2 2.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKE39043.1 - 5.7e-05 21.8 2.9 0.011 14.2 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_S28 PF05577.7 EKE39045.1 - 2.8e-106 355.6 3.1 3.2e-106 355.4 2.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EKE39045.1 - 1.2e-06 28.6 0.0 2.8e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKE39045.1 - 7.4e-05 22.0 0.6 0.00018 20.8 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKE39045.1 - 0.0013 18.4 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE39045.1 - 0.003 17.1 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PfkB PF00294.19 EKE39047.1 - 4.7e-40 137.5 0.1 5.7e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EKE39047.1 - 0.015 14.5 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase KSR1-SAM PF13543.1 EKE39047.1 - 0.095 12.4 0.1 0.22 11.3 0.1 1.6 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 zf-DHHC PF01529.15 EKE39048.1 - 1.6e-26 92.7 15.7 2.3e-26 92.2 10.9 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Tic20 PF09685.5 EKE39049.1 - 2.7e-06 27.3 18.4 3.6e-06 26.9 12.8 1.2 1 0 0 1 1 1 1 Tic20-like protein DUF1129 PF06570.6 EKE39049.1 - 8.6 5.6 9.1 11 5.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Tic20 PF09685.5 EKE39050.1 - 0.31 11.0 28.5 0.66 9.9 19.7 1.7 1 1 0 1 1 1 0 Tic20-like protein CRPA PF05745.6 EKE39050.1 - 1 9.1 8.8 1.4 8.7 6.1 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF2252 PF10009.4 EKE39051.1 - 0.014 14.2 0.4 0.016 14.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF2075 PF09848.4 EKE39051.1 - 0.023 13.7 0.5 0.027 13.4 0.3 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PI-PLC-X PF00388.14 EKE39051.1 - 0.058 12.7 0.4 0.074 12.4 0.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain TCTP PF00838.12 EKE39051.1 - 0.063 13.2 1.0 0.096 12.6 0.7 1.3 1 0 0 1 1 1 0 Translationally controlled tumour protein Trp_repressor PF01371.14 EKE39051.1 - 0.11 12.4 1.9 0.25 11.2 1.4 1.7 1 1 0 1 1 1 0 Trp repressor protein DSPc PF00782.15 EKE39052.1 - 3.7e-06 26.5 0.0 7.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EKE39052.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EKE39052.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EKE39052.1 - 0.045 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 EKE39052.1 - 0.047 13.1 0.1 0.097 12.1 0.1 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 EKE39052.1 - 0.051 12.9 0.1 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family V-SNARE_C PF12352.3 EKE39053.1 - 9.3e-08 32.0 5.0 1.2e-07 31.7 0.7 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EKE39053.1 - 0.0021 18.1 9.7 0.0061 16.6 1.9 2.7 2 2 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus SNARE PF05739.14 EKE39053.1 - 0.0041 16.7 2.0 0.0041 16.7 1.4 3.3 3 1 1 4 4 4 1 SNARE domain FlpD PF02662.11 EKE39053.1 - 0.005 16.5 0.3 0.049 13.3 0.1 2.2 1 1 1 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit DUF3584 PF12128.3 EKE39053.1 - 0.012 13.0 10.7 0.015 12.7 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KapB PF08810.5 EKE39053.1 - 0.03 14.3 1.6 0.068 13.2 0.6 1.9 1 1 1 2 2 2 0 Kinase associated protein B DASH_Duo1 PF08651.5 EKE39053.1 - 0.052 13.1 5.4 0.2 11.2 0.2 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF2959 PF11172.3 EKE39053.1 - 0.31 10.7 7.3 0.94 9.1 1.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) DUF4407 PF14362.1 EKE39053.1 - 0.47 9.3 11.0 0.95 8.3 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tox-HDC PF15656.1 EKE39053.1 - 0.76 10.0 3.7 14 5.9 1.3 3.0 2 1 0 2 2 2 0 Toxin with a H, D/N and C signature DUF1664 PF07889.7 EKE39053.1 - 1.7 8.4 7.4 0.63 9.8 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EKE39053.1 - 2.6 8.3 13.1 0.82 9.9 2.8 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.1 EKE39053.1 - 4.8 7.1 8.3 1.7 8.6 1.7 2.5 1 1 1 2 2 2 0 Up-regulated During Septation Cas_Cmr5 PF09701.5 EKE39054.1 - 0.22 11.6 2.9 0.45 10.7 0.6 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) APG6 PF04111.7 EKE39054.1 - 9.7 5.1 16.6 4.7 6.1 6.1 2.7 3 1 0 3 3 3 0 Autophagy protein Apg6 BCIP PF13862.1 EKE39056.1 - 2.1e-29 102.4 2.3 2.1e-29 102.4 1.6 1.4 2 0 0 2 2 2 1 p21-C-terminal region-binding protein NTR2 PF15458.1 EKE39056.1 - 0.019 14.2 0.9 0.034 13.3 0.6 1.4 1 0 0 1 1 1 0 Nineteen complex-related protein 2 HSP70 PF00012.15 EKE39057.1 - 7.5e-15 53.8 0.6 6.4e-14 50.7 0.3 2.0 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EKE39057.1 - 2.2e-05 23.2 3.5 0.00024 19.8 1.4 2.5 2 1 0 2 2 2 1 MreB/Mbl protein CxxCxxCC PF03692.10 EKE39057.1 - 0.0031 17.9 2.6 0.0033 17.8 0.4 2.1 2 0 0 2 2 2 1 Putative zinc- or iron-chelating domain HMD PF03201.11 EKE39057.1 - 0.064 13.1 0.1 0.26 11.2 0.1 2.0 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Fer4_2 PF12797.2 EKE39057.1 - 2.1 8.4 8.8 0.11 12.4 1.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Spc97_Spc98 PF04130.8 EKE39058.1 - 4.5e-44 150.6 15.0 4.3e-43 147.4 10.4 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family Syntaxin-6_N PF09177.6 EKE39058.1 - 0.006 16.9 0.9 4.2 7.8 0.0 2.7 2 0 0 2 2 2 2 Syntaxin 6, N-terminal LETM1 PF07766.8 EKE39058.1 - 0.021 13.8 2.8 0.11 11.5 0.0 3.0 2 1 1 3 3 3 0 LETM1-like protein RNA_pol_N PF01194.12 EKE39058.1 - 0.036 14.1 0.9 0.1 12.6 0.6 1.8 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit DAD PF02109.11 EKE39059.1 - 7.2e-23 80.7 2.4 9.1e-23 80.4 1.7 1.1 1 0 0 1 1 1 1 DAD family DUF373 PF04123.8 EKE39059.1 - 0.21 10.5 0.7 0.22 10.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) NTP_transf_2 PF01909.18 EKE39060.1 - 0.0016 18.6 1.8 0.0075 16.5 0.4 2.7 2 1 0 2 2 2 1 Nucleotidyltransferase domain TIG PF01833.19 EKE39061.1 - 2.2e-06 27.5 0.3 2.2e-06 27.5 0.2 2.8 2 1 0 2 2 2 1 IPT/TIG domain DUF2644 PF10841.3 EKE39062.1 - 0.044 13.8 0.8 0.044 13.8 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) PIG-P PF08510.7 EKE39062.1 - 0.86 9.2 6.3 0.16 11.5 0.4 2.5 2 1 1 3 3 3 0 PIG-P FGGY_N PF00370.16 EKE39063.1 - 5.1e-70 235.5 0.6 7e-70 235.1 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EKE39063.1 - 3e-47 160.7 0.0 1.1e-46 159.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 EKE39063.1 - 0.014 14.7 0.3 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family RasGEF PF00617.14 EKE39064.1 - 1e-22 80.7 0.1 2.2e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE39064.1 - 1.3e-10 41.2 2.2 2.9e-10 40.1 0.4 2.2 2 1 0 2 2 2 1 RasGEF N-terminal motif zf-UBR PF02207.15 EKE39065.1 - 0.23 11.2 4.2 0.41 10.3 2.9 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Glyco_tranf_2_4 PF13704.1 EKE39066.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 Aminotran_5 PF00266.14 EKE39067.1 - 2.7e-33 115.2 0.0 8.5e-33 113.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V CobU PF02283.11 EKE39068.1 - 0.0057 16.0 0.1 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase Brevenin PF03032.10 EKE39069.1 - 0.045 13.5 0.0 0.045 13.5 0.0 2.1 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family RhoGEF PF00621.15 EKE39070.1 - 5.2e-30 104.6 7.9 5.2e-30 104.6 5.5 2.9 2 1 0 2 2 2 1 RhoGEF domain ArfGap PF01412.13 EKE39070.1 - 1.1e-10 41.3 0.2 1.1e-10 41.3 0.1 3.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf CH PF00307.26 EKE39070.1 - 1.3e-07 31.5 0.3 9e-07 28.9 0.0 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain PH PF00169.24 EKE39070.1 - 2.5e-05 24.4 0.1 2.5e-05 24.4 0.0 3.3 3 0 0 3 3 3 1 PH domain RNase_PH PF01138.16 EKE39071.1 - 5.1e-28 98.0 0.0 6.9e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EKE39071.1 - 2.9e-05 23.8 1.1 5.9e-05 22.9 0.3 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 MRC1 PF09444.5 EKE39071.1 - 0.13 12.6 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 MRC1-like domain Ras PF00071.17 EKE39073.1 - 2.4e-25 88.8 1.8 2.8e-25 88.5 1.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39073.1 - 4.3e-15 56.2 0.1 6.9e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39073.1 - 1.9e-07 30.5 0.1 2.2e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE39073.1 - 3.6e-05 23.6 0.0 6.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EKE39073.1 - 0.00021 21.0 0.1 0.00037 20.2 0.0 1.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EKE39073.1 - 0.00023 21.0 1.8 0.00039 20.3 0.2 1.9 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.5 EKE39073.1 - 0.00041 19.6 0.2 0.0026 17.0 0.0 2.2 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EKE39073.1 - 0.0013 18.8 0.1 0.011 15.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKE39073.1 - 0.0029 17.7 0.0 0.0071 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EKE39073.1 - 0.0031 17.2 0.1 0.017 14.8 0.0 2.1 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EKE39073.1 - 0.0033 17.7 0.3 0.009 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKE39073.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EKE39073.1 - 0.0084 15.9 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EKE39073.1 - 0.0084 15.6 0.1 0.029 13.8 0.0 2.0 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EKE39073.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EKE39073.1 - 0.037 13.0 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin Sigma54_activ_2 PF14532.1 EKE39073.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EKE39073.1 - 0.1 12.1 1.2 1.7 8.1 0.9 2.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EKE39073.1 - 0.11 12.3 0.6 0.55 10.0 0.4 2.3 1 1 0 1 1 1 0 Dynamin family AAA_17 PF13207.1 EKE39073.1 - 0.12 13.1 0.0 0.17 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Defensin_1 PF00323.14 EKE39074.1 - 0.14 12.4 0.5 0.26 11.6 0.4 1.4 1 0 0 1 1 1 0 Mammalian defensin VSP PF03302.8 EKE39075.1 - 4.6e-13 48.5 133.9 8.2e-06 24.7 14.0 5.8 1 1 5 6 6 6 6 Giardia variant-specific surface protein Mem_trans PF03547.13 EKE39077.1 - 3e-31 108.0 14.0 8.7e-31 106.5 9.7 1.7 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 EKE39078.1 - 5.3e-19 68.3 0.4 8.9e-19 67.6 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39078.1 - 1.1e-13 50.8 0.2 1.5e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE39078.1 - 0.034 13.2 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RasGEF PF00617.14 EKE39079.1 - 2e-22 79.8 2.5 4.2e-22 78.7 1.1 1.9 2 0 0 2 2 2 1 RasGEF domain XPG_I PF00867.13 EKE39080.1 - 0.009 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EKE39080.1 - 0.013 14.9 0.1 0.048 13.1 0.0 1.7 1 1 1 2 2 2 0 XPG domain containing ERAP1_C PF11838.3 EKE39080.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain SPOB_a PF14689.1 EKE39080.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF489 PF04356.7 EKE39081.1 - 0.073 12.6 5.2 0.026 14.0 1.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF489) TLD PF07534.11 EKE39082.1 - 2.6e-10 40.4 5.7 7.9e-08 32.3 0.8 2.4 2 0 0 2 2 2 2 TLD DUF2642 PF10842.3 EKE39082.1 - 0.065 12.7 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) LAMTOR PF15454.1 EKE39082.1 - 0.11 12.8 0.1 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Methyltransf_31 PF13847.1 EKE39084.1 - 2.9e-18 65.9 0.1 4.2e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE39084.1 - 3.4e-15 56.5 0.0 5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE39084.1 - 1.5e-09 37.7 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE39084.1 - 1.7e-08 34.8 0.0 3.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKE39084.1 - 9.4e-08 32.3 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE39084.1 - 1.5e-07 31.8 0.0 3.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE39084.1 - 3.1e-07 30.4 0.0 4.9e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EKE39084.1 - 2.4e-06 26.8 0.1 4.2e-06 26.0 0.1 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EKE39084.1 - 5.7e-06 25.8 0.0 7.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EKE39084.1 - 3.4e-05 23.1 0.0 5.2e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.8 EKE39084.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.15 EKE39084.1 - 0.00039 19.5 0.3 0.0005 19.2 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EKE39084.1 - 0.00086 18.7 0.1 0.0019 17.6 0.0 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EKE39084.1 - 0.0013 17.4 0.0 0.0023 16.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 EKE39084.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKE39084.1 - 0.0051 16.3 0.0 0.0082 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AviRa PF11599.3 EKE39084.1 - 0.0078 15.2 0.0 0.026 13.5 0.0 1.7 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Pox_MCEL PF03291.11 EKE39084.1 - 0.013 14.3 0.0 0.18 10.6 0.0 2.2 1 1 0 1 1 1 0 mRNA capping enzyme FmrO PF07091.6 EKE39084.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF249 PF03158.8 EKE39084.1 - 0.097 12.1 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Multigene family 530 protein Myosin_head PF00063.16 EKE39085.1 - 5.1e-235 781.6 3.6 5.1e-235 781.6 2.5 4.2 2 1 2 5 5 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EKE39085.1 - 9.6e-45 152.6 354.2 6.1e-17 60.6 67.2 6.0 1 1 5 6 6 6 6 Myosin tail Reo_sigmaC PF04582.7 EKE39085.1 - 1.8e-14 53.6 107.3 5e-06 25.9 4.0 11.3 3 3 7 11 11 11 9 Reovirus sigma C capsid protein IncA PF04156.9 EKE39085.1 - 9.4e-14 51.4 293.6 0.0013 18.3 13.7 13.0 1 1 11 12 12 12 7 IncA protein Filament PF00038.16 EKE39085.1 - 9.4e-10 38.4 296.2 0.0032 16.9 29.6 9.9 1 1 7 9 9 9 8 Intermediate filament protein AAA_13 PF13166.1 EKE39085.1 - 9e-05 21.1 34.9 9e-05 21.1 24.2 9.2 2 1 7 9 9 9 5 AAA domain CENP-F_leu_zip PF10473.4 EKE39085.1 - 0.00019 21.2 26.0 0.00019 21.2 18.0 13.8 2 1 13 16 16 14 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EKE39085.1 - 0.00036 19.1 59.9 0.00036 19.1 41.5 7.8 1 1 5 7 7 4 1 Weak chloroplast movement under blue light ADIP PF11559.3 EKE39085.1 - 0.00056 19.8 9.4 0.00056 19.8 6.5 17.5 2 2 15 17 17 16 6 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 EKE39085.1 - 0.0039 17.0 22.9 0.0039 17.0 15.9 15.0 1 1 12 14 14 14 4 Tropomyosin like IQ PF00612.22 EKE39085.1 - 0.31 10.8 2.9 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Cast PF10174.4 EKE39085.1 - 0.42 8.6 319.4 0.11 10.4 32.6 5.2 1 1 3 4 4 4 0 RIM-binding protein of the cytomatrix active zone UCH PF00443.24 EKE39086.1 - 2.2e-45 154.9 15.3 2.2e-45 154.9 10.6 4.4 2 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase KSR1-SAM PF13543.1 EKE39087.1 - 0.00097 18.9 2.2 0.00097 18.9 1.5 2.6 2 1 0 2 2 2 1 SAM like domain present in kinase suppressor RAS 1 Fib_alpha PF08702.5 EKE39087.1 - 0.0023 18.0 12.7 0.0023 18.0 8.8 3.6 3 2 1 4 4 4 1 Fibrinogen alpha/beta chain family Cob_adeno_trans PF01923.13 EKE39087.1 - 0.73 9.6 4.5 1 9.0 0.7 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase PhoU PF01895.14 EKE39087.1 - 1.4 9.4 5.7 0.99 9.8 0.7 2.4 2 0 0 2 2 2 0 PhoU domain Cation_efflux PF01545.16 EKE39088.1 - 3.2e-68 229.8 0.9 3.9e-68 229.5 0.6 1.1 1 0 0 1 1 1 1 Cation efflux family OSTbeta PF15048.1 EKE39088.1 - 0.03 14.4 0.1 0.094 12.7 0.1 1.8 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF3816 PF12822.2 EKE39088.1 - 8 6.3 16.4 3.4 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) DSPc PF00782.15 EKE39089.1 - 3e-29 101.3 0.1 5.1e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE39089.1 - 0.0012 18.2 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EKE39089.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate RIC1 PF07064.8 EKE39091.1 - 3.4e-10 39.8 0.1 7.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RIC1 Corona_NS1 PF06145.6 EKE39091.1 - 0.0014 17.9 1.9 0.0037 16.5 1.3 1.8 1 0 0 1 1 1 1 Coronavirus nonstructural protein NS1 PGM_PMM_I PF02878.11 EKE39092.1 - 6.8e-34 116.3 0.2 1.2e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EKE39092.1 - 4.9e-22 78.1 0.0 1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EKE39092.1 - 3.8e-11 43.2 0.0 1e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EKE39092.1 - 1e-10 41.4 0.0 2.3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SIN1 PF05422.7 EKE39094.1 - 6.4e-09 34.8 4.7 3.9e-05 22.3 0.1 3.3 2 1 1 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) zf-DHHC PF01529.15 EKE39095.1 - 1.3e-39 135.3 3.5 1.3e-39 135.3 2.4 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF35_N PF12172.3 EKE39095.1 - 1.2 9.1 7.3 3.1 7.8 5.1 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PSI PF01437.20 EKE39095.1 - 2.9 8.1 9.6 13 6.0 6.7 1.9 1 1 0 1 1 1 0 Plexin repeat Phage_Cox PF10743.4 EKE39096.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Regulatory phage protein cox DUF4131 PF13567.1 EKE39098.1 - 0.005 16.2 0.3 0.011 15.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) FUSC_2 PF13515.1 EKE39098.1 - 4.8 7.1 9.9 2.7 7.9 0.4 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein-like FRG1 PF06229.7 EKE39100.1 - 0.24 10.8 5.3 0.43 10.0 3.6 1.4 1 0 0 1 1 1 0 FRG1-like family TRAM_LAG1_CLN8 PF03798.11 EKE39101.1 - 2.1e-25 89.4 22.2 2.1e-25 89.4 15.4 1.5 2 0 0 2 2 2 1 TLC domain HSP20 PF00011.16 EKE39102.1 - 1e-13 50.9 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Sec7 PF01369.15 EKE39103.1 - 3.7e-12 46.3 1.9 3.7e-12 46.3 1.3 3.7 4 0 0 4 4 4 1 Sec7 domain Histone PF00125.19 EKE39105.1 - 4.1e-28 97.3 0.4 6.5e-28 96.6 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EKE39105.1 - 3.4e-05 23.9 0.0 6.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EKE39105.1 - 0.016 15.2 0.1 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EKE39105.1 - 0.028 13.6 3.8 0.043 13.0 2.6 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Inositol_P PF00459.20 EKE39106.1 - 9.3e-57 192.3 0.1 1.2e-56 192.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MutS_V PF00488.16 EKE39107.1 - 1.2e-79 266.9 0.4 2.5e-79 265.9 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 EKE39107.1 - 3.3e-31 107.6 0.0 8.1e-31 106.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 EKE39107.1 - 7e-31 107.6 0.1 1.2e-30 106.8 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EKE39107.1 - 4.6e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain II NTPase_1 PF03266.10 EKE39107.1 - 0.011 15.4 1.7 0.046 13.4 0.5 2.5 2 1 0 2 2 2 0 NTPase AAA_28 PF13521.1 EKE39107.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MutS_IV PF05190.13 EKE39107.1 - 0.28 11.3 4.3 0.25 11.5 0.9 2.5 2 0 0 2 2 2 0 MutS family domain IV AAA_23 PF13476.1 EKE39107.1 - 7.3 6.8 13.6 0.49 10.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain DUF3755 PF12579.3 EKE39108.1 - 0.036 13.4 0.0 0.036 13.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3755) DEAD PF00270.24 EKE39109.1 - 3.3e-32 111.3 0.2 8.3e-32 109.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE39109.1 - 3.3e-21 74.9 0.3 5.3e-12 45.4 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EKE39109.1 - 0.00077 19.3 0.0 0.00077 19.3 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit LRR_5 PF13306.1 EKE39110.1 - 2.7e-75 250.2 65.3 2.4e-30 104.8 11.4 4.8 3 1 2 5 5 5 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE39110.1 - 3e-28 97.3 21.1 1.7e-07 30.8 0.0 6.5 3 2 4 7 7 7 5 Leucine rich repeat HECT PF00632.20 EKE39111.1 - 4.2e-76 256.1 1.8 4.2e-76 256.1 1.2 2.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DDR PF08841.5 EKE39111.1 - 0.21 10.3 0.0 0.38 9.5 0.0 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain OppC_N PF12911.2 EKE39112.1 - 1 8.7 6.7 3.4 7.1 4.6 1.9 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C ArfGap PF01412.13 EKE39113.1 - 4.2e-34 116.8 0.3 1.4e-33 115.1 0.2 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank PF00023.25 EKE39113.1 - 1.4e-14 53.0 0.6 3.2e-08 32.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EKE39113.1 - 6.7e-14 52.0 0.4 1.6e-13 50.7 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE39113.1 - 2.1e-11 43.6 0.1 5.7e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE39113.1 - 1.6e-08 34.0 0.5 0.00012 21.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EKE39113.1 - 2.3e-07 31.1 0.3 1.3e-05 25.5 0.1 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF869 PF05911.6 EKE39113.1 - 0.14 10.4 10.2 0.2 9.8 7.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Metallophos PF00149.23 EKE39115.1 - 1.5e-24 86.5 0.0 4.5e-24 84.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE39115.1 - 0.008 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 EKE39116.1 - 3.6e-61 202.7 1.5 2e-22 78.5 0.1 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39116.1 - 5.7e-46 154.3 0.9 1.5e-16 60.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39116.1 - 1.3e-36 124.2 1.3 1.4e-11 44.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKE39116.1 - 4.2e-05 23.2 0.6 0.57 9.9 0.0 3.4 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 EKE39116.1 - 9e-05 22.2 2.2 0.034 13.9 0.0 2.6 2 1 1 3 3 3 2 RNA binding motif Nup35_RRM PF05172.8 EKE39116.1 - 0.00018 21.2 4.7 0.026 14.2 1.1 3.0 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EKE39116.1 - 0.011 15.4 0.5 4.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 EKE39116.1 - 0.033 14.1 0.1 0.63 10.0 0.0 2.8 2 1 0 2 2 2 0 RNA binding domain DUF3078 PF11276.3 EKE39116.1 - 0.058 13.5 0.4 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3078) TLD PF07534.11 EKE39117.1 - 3.3e-06 27.1 0.7 4.4e-06 26.7 0.5 1.3 1 0 0 1 1 1 1 TLD zinc_ribbon_2 PF13240.1 EKE39118.1 - 0.093 12.2 0.2 0.093 12.2 0.2 4.5 4 1 0 4 4 4 0 zinc-ribbon domain zf-ISL3 PF14690.1 EKE39118.1 - 0.19 11.7 0.3 0.19 11.7 0.2 3.7 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-FPG_IleRS PF06827.9 EKE39118.1 - 0.22 11.2 7.9 4.5 7.0 0.1 3.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS UPF0547 PF10571.4 EKE39118.1 - 0.22 11.2 0.0 0.22 11.2 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DZR PF12773.2 EKE39118.1 - 0.33 10.8 15.2 0.097 12.5 1.4 3.4 2 2 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EKE39118.1 - 0.45 9.7 0.1 0.45 9.7 0.1 4.4 4 1 0 4 4 4 0 zinc-ribbon domain zf-RING_3 PF14369.1 EKE39118.1 - 0.97 9.4 0.1 0.97 9.4 0.1 3.6 3 1 0 3 3 3 0 zinc-finger zf-Dof PF02701.10 EKE39118.1 - 1 9.3 15.1 0.089 12.7 4.3 2.9 3 0 0 3 3 3 0 Dof domain, zinc finger TFIIS_C PF01096.13 EKE39118.1 - 1.1 8.9 12.1 1.6 8.3 0.2 4.2 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 EKE39118.1 - 1.7 8.6 12.7 9.3 6.3 0.1 4.3 4 0 0 4 4 4 0 Zinc ribbon domain zf-C4_Topoisom PF01396.14 EKE39118.1 - 3.8 7.1 8.8 12 5.5 2.1 2.7 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger NOB1_Zn_bind PF08772.6 EKE39118.1 - 4.3 7.2 8.3 13 5.7 0.2 3.0 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Lar_restr_allev PF14354.1 EKE39118.1 - 8.1 6.8 12.9 0.22 11.8 0.9 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar Pkinase PF00069.20 EKE39120.1 - 1.8e-66 223.9 0.0 2.1e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39120.1 - 1.2e-37 129.4 0.0 1.6e-37 128.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39120.1 - 1e-09 37.8 0.0 2.4e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EKE39120.1 - 0.00015 21.5 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EKE39120.1 - 0.00079 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EKE39120.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 UPF0137 PF03677.8 EKE39121.1 - 0.052 13.0 0.5 0.057 12.9 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DUF2116 PF09889.4 EKE39122.1 - 3.4 7.5 7.6 2.7 7.8 0.3 2.8 2 1 1 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DCP2 PF05026.8 EKE39124.1 - 5.9e-15 54.9 4.0 1.3e-14 53.8 2.8 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EKE39124.1 - 1.1e-10 41.2 0.0 2.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.27 EKE39125.1 - 0.013 15.3 1.8 1.3 9.0 0.1 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat RPAP1_C PF08620.5 EKE39126.1 - 6.2e-15 54.8 0.0 1.6e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal Reo_sigmaC PF04582.7 EKE39127.1 - 0.024 13.8 3.2 0.13 11.3 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EKE39127.1 - 2.7 5.1 35.4 0.33 8.2 11.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF148 PF02520.12 EKE39127.1 - 4.4 7.1 25.4 4.9 6.9 5.7 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF148 IncA PF04156.9 EKE39127.1 - 7 6.1 43.4 10 5.6 11.3 2.4 1 1 1 2 2 2 0 IncA protein AvrB_AvrC PF05394.6 EKE39127.1 - 7.6 5.4 11.2 1.3 7.9 4.1 1.9 1 1 0 2 2 2 0 Avirulence protein APG6 PF04111.7 EKE39127.1 - 9 5.2 44.3 1.2 8.1 12.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Pkinase PF00069.20 EKE39128.1 - 3.2e-51 173.9 0.1 4.7e-51 173.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39128.1 - 4.5e-50 170.1 0.0 5.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKE39128.1 - 5.4e-05 22.1 0.5 0.00012 21.0 0.4 1.5 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF4083 PF13314.1 EKE39128.1 - 0.8 9.5 9.1 0.42 10.4 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Ras PF00071.17 EKE39129.1 - 1.2e-47 161.3 0.1 1.8e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39129.1 - 8.7e-14 52.0 0.4 4.7e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39129.1 - 5.4e-09 35.5 0.1 7.2e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39129.1 - 3.9e-05 23.1 0.1 7.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39129.1 - 0.0076 16.1 0.1 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE39129.1 - 0.056 12.7 0.1 0.15 11.3 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_21 PF13304.1 EKE39129.1 - 0.1 12.5 4.3 0.12 12.3 3.0 1.1 1 0 0 1 1 1 0 AAA domain RE_TdeIII PF09520.5 EKE39129.1 - 0.67 9.2 5.8 9.1 5.5 2.2 2.5 2 1 1 3 3 3 0 Type II restriction endonuclease, TdeIII DUF4602 PF15375.1 EKE39129.1 - 0.87 9.6 12.1 1.5 8.8 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) PPTA PF01239.17 EKE39130.1 - 5.7e-40 133.0 8.8 4.4e-10 38.4 0.7 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Flexi_CP PF00286.15 EKE39130.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral coat protein PDZ_2 PF13180.1 EKE39131.1 - 1.3e-07 31.3 0.1 2.3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EKE39131.1 - 3.7e-05 23.8 0.1 6.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Seryl_tRNA_N PF02403.17 EKE39131.1 - 0.018 15.0 0.4 0.03 14.3 0.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YvrJ PF12841.2 EKE39131.1 - 0.078 12.2 0.5 0.23 10.7 0.1 2.0 2 0 0 2 2 2 0 YvrJ protein family DNA_repr_REX1B PF14966.1 EKE39131.1 - 0.084 13.2 0.2 13 6.2 0.0 2.4 2 0 0 2 2 2 0 DNA repair REX1-B Spc24 PF08286.6 EKE39131.1 - 0.43 10.2 5.4 5.3 6.7 0.1 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF2046 PF09755.4 EKE39131.1 - 2.9 6.7 7.7 11 4.7 5.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) IncA PF04156.9 EKE39131.1 - 3.8 7.0 4.8 10 5.6 3.3 1.6 1 1 0 1 1 1 0 IncA protein Pkinase PF00069.20 EKE39132.1 - 4.1e-61 206.4 0.0 4.7e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39132.1 - 4.4e-25 88.2 0.0 1.2e-24 86.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39132.1 - 1.7e-05 23.9 0.0 3.7e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EKE39132.1 - 0.0026 17.3 1.6 0.005 16.4 1.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKE39132.1 - 0.0073 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ACT_3 PF10000.4 EKE39132.1 - 0.042 13.5 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain Kdo PF06293.9 EKE39132.1 - 0.065 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Yos1 PF08571.5 EKE39135.1 - 1.4e-17 63.5 0.3 1.5e-17 63.4 0.2 1.0 1 0 0 1 1 1 1 Yos1-like Fun_ATP-synt_8 PF05933.8 EKE39135.1 - 3 7.9 5.3 9.2 6.3 0.2 2.2 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Fip1 PF05182.8 EKE39136.1 - 0.023 13.9 0.3 0.058 12.6 0.2 1.7 1 0 0 1 1 1 0 Fip1 motif HAD_2 PF13419.1 EKE39137.1 - 2e-18 67.2 0.0 2.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE39137.1 - 9.8e-08 32.6 1.3 4.9e-07 30.3 0.9 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EKE39137.1 - 0.00015 21.6 0.1 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE39137.1 - 0.00042 20.5 0.0 0.00052 20.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EKE39137.1 - 0.0027 17.3 0.1 0.14 11.7 0.1 2.3 1 1 0 1 1 1 1 Acid Phosphatase Hydrolase_3 PF08282.7 EKE39137.1 - 0.003 17.1 0.4 0.15 11.5 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE39137.1 - 0.046 13.4 0.1 0.16 11.6 0.0 1.9 3 0 0 3 3 3 0 HAD-hyrolase-like Fer4_12 PF13353.1 EKE39137.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Aldo_ket_red PF00248.16 EKE39138.1 - 8.5e-57 192.1 0.0 1e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Metallophos PF00149.23 EKE39139.1 - 2.2e-37 128.4 0.5 3.4e-37 127.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MRL1 PF13003.2 EKE39140.1 - 0.12 12.2 1.6 1.2 8.9 0.1 2.5 1 1 1 2 2 2 0 Ribosomal protein L1 EF-hand_1 PF00036.27 EKE39141.1 - 1.4e-27 92.8 7.9 1.9e-06 26.7 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKE39141.1 - 9.6e-25 86.5 4.1 4.2e-12 46.0 0.2 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE39141.1 - 6.4e-24 81.6 5.0 4.6e-05 22.9 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKE39141.1 - 1.4e-23 81.0 8.2 7e-06 25.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EKE39141.1 - 9.3e-23 79.6 7.8 3.8e-05 23.2 0.1 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKE39141.1 - 3.4e-08 33.5 0.0 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EKE39141.1 - 9.6e-07 28.3 3.0 0.35 10.5 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EKE39141.1 - 0.00064 19.4 2.7 0.56 9.9 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 EKE39141.1 - 0.0011 18.9 0.7 0.059 13.3 0.3 3.1 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Cro PF09048.5 EKE39141.1 - 0.005 16.4 1.1 0.43 10.2 0.0 3.2 2 1 1 3 3 3 1 Cro DUF1456 PF07308.8 EKE39141.1 - 0.11 12.6 0.5 2.9 7.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Dockerin_1 PF00404.13 EKE39141.1 - 2.8 7.7 15.2 0.8 9.5 0.6 4.1 4 0 0 4 4 4 0 Dockerin type I repeat A_deaminase PF00962.17 EKE39142.1 - 2.6e-119 398.0 0.3 2.2e-61 207.6 0.0 2.5 2 1 0 2 2 2 2 Adenosine/AMP deaminase zf-B_box PF00643.19 EKE39142.1 - 0.0084 15.9 9.6 0.027 14.3 6.6 1.9 1 0 0 1 1 1 1 B-box zinc finger TCP PF03634.8 EKE39143.1 - 0.00098 19.5 0.4 0.0017 18.7 0.3 1.6 1 1 0 1 1 1 1 TCP family transcription factor RHH_1 PF01402.16 EKE39143.1 - 0.049 13.5 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family SWIM PF04434.12 EKE39143.1 - 3.6 7.1 8.9 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 SWIM zinc finger DENN PF02141.16 EKE39144.1 - 2.3e-14 53.5 4.3 8.6e-13 48.4 3.0 2.5 1 1 0 1 1 1 1 DENN (AEX-3) domain Methyltransf_4 PF02390.12 EKE39146.1 - 1.3e-22 79.8 0.1 1.3e-22 79.8 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase PPR PF01535.15 EKE39146.1 - 0.0014 18.4 0.1 11 6.2 0.1 4.5 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 EKE39146.1 - 0.013 15.4 0.3 11 6.1 0.0 3.5 2 1 2 4 4 4 0 PPR repeat family PPR_3 PF13812.1 EKE39146.1 - 0.022 14.9 0.0 1.8 9.0 0.0 3.4 3 1 1 4 4 4 0 Pentatricopeptide repeat domain Methyltransf_26 PF13659.1 EKE39146.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AKAP7_NLS PF10469.4 EKE39147.1 - 1.2e-20 74.1 0.4 1.3e-20 74.0 0.3 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF4473 PF14747.1 EKE39147.1 - 0.00021 21.4 0.5 0.00046 20.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) HVSL PF09749.4 EKE39147.1 - 0.0027 16.7 0.1 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Phage_connect_1 PF05135.8 EKE39147.1 - 0.0076 16.4 0.5 1.4 9.0 0.2 2.2 2 0 0 2 2 2 1 Phage gp6-like head-tail connector protein Phage_RpbA PF10789.4 EKE39147.1 - 0.019 14.8 0.3 0.024 14.4 0.2 1.2 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA DUF3861 PF12977.2 EKE39147.1 - 0.028 14.5 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) DUF4413 PF14372.1 EKE39147.1 - 0.035 14.0 0.8 0.06 13.3 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) Hydant_A_N PF05378.8 EKE39147.1 - 0.068 12.6 0.1 0.08 12.4 0.1 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Hormone_1 PF00103.15 EKE39147.1 - 0.12 11.7 0.3 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 Somatotropin hormone family P-II PF00543.17 EKE39147.1 - 0.37 11.2 2.1 12 6.4 0.5 2.2 1 1 1 2 2 2 0 Nitrogen regulatory protein P-II Dynein_light PF01221.13 EKE39149.1 - 1.1e-26 92.6 2.0 1.2e-26 92.5 1.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PRA1 PF03208.14 EKE39149.1 - 0.0092 15.3 0.4 0.018 14.4 0.2 1.6 1 1 1 2 2 2 1 PRA1 family protein TLD PF07534.11 EKE39151.1 - 0.0006 19.8 1.6 0.00096 19.1 1.1 1.4 1 0 0 1 1 1 1 TLD Aminotran_1_2 PF00155.16 EKE39152.1 - 9.9e-11 41.1 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKE39152.1 - 0.052 12.6 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Pkinase_Tyr PF07714.12 EKE39153.1 - 5.1e-35 120.8 0.0 8.7e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39153.1 - 1.7e-30 106.0 0.1 2.8e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EKE39153.1 - 1.5e-27 95.7 2.1 4.2e-10 39.8 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKE39153.1 - 1.6e-26 92.1 5.2 7.9e-07 29.4 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EKE39153.1 - 2.5e-25 86.9 3.9 8e-07 28.5 0.0 6.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EKE39153.1 - 4e-22 77.7 5.3 1.1e-09 38.1 0.0 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE39153.1 - 9e-22 74.9 9.8 3.5e-05 23.6 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat RtcB PF01139.12 EKE39154.1 - 1.5e-141 472.2 0.1 1.9e-141 471.9 0.1 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB UDPG_MGDP_dh_C PF03720.10 EKE39154.1 - 0.028 14.5 0.1 0.072 13.2 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Not1 PF04054.10 EKE39155.1 - 1.7e-47 162.1 17.5 3.8e-25 88.5 5.2 2.9 2 0 0 2 2 2 2 CCR4-Not complex component, Not1 Nuc_sug_transp PF04142.10 EKE39156.1 - 2.3e-66 223.3 15.6 3.7e-66 222.6 10.8 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EKE39156.1 - 2.4e-09 37.0 30.3 1.7e-06 27.7 8.9 3.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EKE39156.1 - 9e-08 32.2 31.2 1e-07 32.0 6.8 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EKE39156.1 - 3.5e-07 29.4 9.7 3.5e-07 29.4 6.7 2.3 1 1 1 2 2 2 2 UAA transporter family EmrE PF13536.1 EKE39156.1 - 0.00012 22.2 23.1 0.00022 21.3 5.1 2.8 2 0 0 2 2 2 2 Multidrug resistance efflux transporter DUF486 PF04342.7 EKE39156.1 - 0.051 13.6 6.4 0.68 10.0 4.0 2.7 1 1 1 2 2 2 0 Protein of unknown function, DUF486 Consortin_C PF15281.1 EKE39156.1 - 0.16 11.4 1.6 0.38 10.2 0.3 2.3 2 0 0 2 2 2 0 Consortin C-terminus DUF1765 PF08578.5 EKE39157.1 - 3.2e-16 59.5 10.9 3.2e-16 59.5 7.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) CLTH PF10607.4 EKE39157.1 - 0.012 15.3 1.8 0.019 14.6 0.2 2.2 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain RNA_pol_A_bac PF01000.21 EKE39159.1 - 3.3e-26 91.6 0.1 4.4e-25 88.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EKE39159.1 - 1.6e-08 33.4 0.0 1.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TLD PF07534.11 EKE39160.1 - 0.00069 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 TLD Nnf1 PF03980.9 EKE39160.1 - 0.17 11.9 1.1 0.24 11.3 0.4 1.6 1 1 1 2 2 2 0 Nnf1 BtpA PF03437.10 EKE39161.1 - 8.9e-66 221.7 0.6 1e-65 221.5 0.4 1.0 1 0 0 1 1 1 1 BtpA family Trp_syntA PF00290.15 EKE39161.1 - 0.0025 16.4 0.1 0.0035 15.9 0.1 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PRAI PF00697.17 EKE39161.1 - 0.003 17.1 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase His_biosynth PF00977.16 EKE39161.1 - 0.0063 15.7 0.1 0.015 14.6 0.1 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.12 EKE39161.1 - 0.012 14.9 0.2 0.024 13.8 0.0 1.7 2 0 0 2 2 2 0 PcrB family MerB PF03243.10 EKE39161.1 - 0.074 12.8 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Alkylmercury lyase WD40 PF00400.27 EKE39162.1 - 1e-23 82.2 2.1 6.2e-07 29.0 0.3 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Utp12 PF04003.7 EKE39162.1 - 1.5e-05 24.8 1.7 2.8e-05 23.9 1.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Apc4_WD40 PF12894.2 EKE39162.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SBDS PF01172.13 EKE39163.1 - 8.9e-15 54.2 0.7 1.4e-14 53.5 0.1 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EKE39163.1 - 4.2e-14 52.3 0.1 6.6e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain TPK_catalytic PF04263.11 EKE39163.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Sec20 PF03908.8 EKE39164.1 - 0.00015 21.3 1.2 0.0002 21.0 0.8 1.2 1 0 0 1 1 1 1 Sec20 DUF1241 PF06840.6 EKE39164.1 - 0.015 14.5 0.1 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Laminin_II PF06009.7 EKE39164.1 - 0.04 13.6 0.4 0.047 13.4 0.3 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF2951 PF11166.3 EKE39164.1 - 0.088 12.6 1.0 0.11 12.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) NYD-SP28 PF14772.1 EKE39164.1 - 0.089 12.8 0.4 0.12 12.4 0.3 1.1 1 0 0 1 1 1 0 Sperm tail SPRY PF00622.23 EKE39165.1 - 8.6e-13 48.4 0.2 1.6e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 SPRY domain DUF4368 PF14287.1 EKE39166.1 - 0.081 12.7 1.7 0.46 10.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) Metallophos PF00149.23 EKE39167.1 - 0.0028 17.0 2.4 0.015 14.7 1.6 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase_Tyr PF07714.12 EKE39168.1 - 1.2e-47 162.1 0.1 2.1e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39168.1 - 2.8e-47 161.0 0.5 5e-47 160.2 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain AMP-binding PF00501.23 EKE39169.1 - 1.5e-68 231.0 0.0 2.2e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKE39169.1 - 1.4e-44 151.8 0.1 2.3e-44 151.2 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 EKE39169.1 - 7.7e-17 62.0 0.0 1.9e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EKE39169.1 - 6.4e-09 34.9 1.6 1.2e-08 33.9 1.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKE39169.1 - 2.2e-06 27.2 0.1 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EKE39169.1 - 0.00021 21.4 0.0 0.00054 20.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EKE39169.1 - 0.0012 17.8 0.2 0.0037 16.2 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EKE39169.1 - 0.0053 16.4 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKE39169.1 - 0.0054 16.6 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase HSP70 PF00012.15 EKE39170.1 - 1.3e-29 102.6 0.8 1.3e-29 102.6 0.6 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EKE39170.1 - 0.0002 20.0 0.6 0.0002 20.0 0.4 2.6 3 1 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.11 EKE39170.1 - 0.093 12.3 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain RRM_6 PF14259.1 EKE39171.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.14 EKE39172.1 - 3.3e-24 85.6 4.4 3.3e-24 85.6 3.0 2.6 3 1 0 3 3 3 1 RasGEF domain RIX1 PF08167.7 EKE39173.1 - 0.1 12.2 0.2 5.2 6.7 0.1 2.1 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis PUF PF00806.14 EKE39174.1 - 1.1e-32 109.6 12.0 2.1e-07 30.0 0.1 5.3 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat CTD_bind PF04818.8 EKE39174.1 - 0.022 14.9 1.2 0.91 9.8 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase II-binding domain. DUF2905 PF11146.3 EKE39176.1 - 0.14 12.1 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) Fer4 PF00037.22 EKE39177.1 - 2e-14 52.4 21.6 6.7e-10 38.1 3.7 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EKE39177.1 - 4.4e-13 48.4 18.6 4.7e-09 35.7 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EKE39177.1 - 5.4e-11 42.1 26.7 9.6e-08 31.7 11.5 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EKE39177.1 - 1.4e-10 41.3 15.7 2.3e-10 40.6 10.9 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKE39177.1 - 5.2e-09 36.2 16.0 9.4e-09 35.4 11.1 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKE39177.1 - 2.1e-08 34.0 25.1 1.3e-05 25.1 11.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE39177.1 - 6.3e-08 32.2 16.9 3.4e-07 29.9 12.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE39177.1 - 1.9e-07 30.5 19.3 3.9e-06 26.4 2.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 EKE39177.1 - 5.6e-07 30.2 12.9 8.3e-05 23.2 0.2 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 EKE39177.1 - 2.6e-06 27.3 19.4 2e-05 24.5 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EKE39177.1 - 1.2e-05 25.5 7.7 0.0035 17.6 0.5 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.2 EKE39177.1 - 0.00014 22.1 6.9 0.00014 22.1 4.8 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.1 EKE39177.1 - 0.00026 21.3 22.3 0.00054 20.3 3.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EKE39177.1 - 0.0061 17.1 21.0 0.098 13.2 14.6 2.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.1 EKE39177.1 - 0.1 12.9 21.0 15 6.1 14.6 2.6 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_11 PF13247.1 EKE39177.1 - 0.23 11.3 8.0 0.77 9.6 5.6 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain LSM PF01423.17 EKE39178.1 - 2.9e-17 61.9 0.2 3.8e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKE39178.1 - 0.0018 18.1 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF669 PF05037.8 EKE39178.1 - 0.039 13.8 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) SH3_1 PF00018.23 EKE39179.1 - 1.8e-17 62.4 0.1 2.8e-06 26.5 0.0 4.6 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.12 EKE39179.1 - 1.7e-16 59.4 0.2 0.00014 21.2 0.0 5.1 5 0 0 5 5 5 4 Variant SH3 domain SH3_9 PF14604.1 EKE39179.1 - 4.6e-16 58.1 0.4 1.3e-06 27.8 0.0 5.2 5 0 0 5 5 5 2 Variant SH3 domain SH3_3 PF08239.6 EKE39179.1 - 0.0013 18.8 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain DUF239 PF03080.10 EKE39179.1 - 0.0025 16.9 0.2 0.5 9.4 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF239) PC4 PF02229.11 EKE39180.1 - 5.7e-18 63.8 0.4 1.5e-17 62.5 0.3 1.7 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Neur_chan_memb PF02932.11 EKE39180.1 - 0.13 12.0 8.1 0.15 11.9 5.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 EKE39180.1 - 1.7 7.1 10.2 1.8 7.0 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-4B PF06273.6 EKE39180.1 - 2.9 6.5 17.1 3.5 6.2 11.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Ycf1 PF05758.7 EKE39180.1 - 3.7 5.1 19.1 3.4 5.2 13.2 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 EKE39180.1 - 4.6 6.9 13.4 6 6.6 9.3 1.3 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.3 EKE39180.1 - 6.6 5.3 25.9 8.7 4.9 17.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 EKE39180.1 - 6.9 6.6 26.7 9 6.2 18.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HNOB PF07700.10 EKE39181.1 - 0.031 13.8 0.7 0.091 12.2 0.1 1.9 2 0 0 2 2 2 0 Heme NO binding eIF3_p135 PF12807.2 EKE39181.1 - 0.042 13.7 0.6 0.06 13.2 0.4 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Arrestin_C PF02752.17 EKE39182.1 - 1e-06 28.9 0.5 1.5e-05 25.0 0.2 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EKE39182.1 - 1.2e-06 28.4 0.2 4.6e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EKE39182.1 - 0.008 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like AMP-binding PF00501.23 EKE39183.1 - 1.2e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKE39183.1 - 0.0071 17.2 0.0 0.015 16.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L44 PF00935.14 EKE39184.1 - 9.7e-34 115.2 16.7 1.3e-33 114.7 11.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 EKE39184.1 - 0.0026 17.5 0.6 0.0026 17.5 0.4 2.3 1 1 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like FAM74 PF15026.1 EKE39184.1 - 0.063 12.9 0.7 0.08 12.5 0.5 1.1 1 0 0 1 1 1 0 FAM74 protein DUF329 PF03884.9 EKE39184.1 - 6.2 6.4 8.1 12 5.5 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF329) Ribosomal_L24e PF01246.15 EKE39185.1 - 6.2e-06 25.9 0.3 6.2e-06 25.9 0.2 2.4 2 1 0 2 2 2 1 Ribosomal protein L24e VirionAssem_T7 PF11653.3 EKE39185.1 - 0.031 15.0 8.9 0.042 14.6 6.2 1.2 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Clathrin_lg_ch PF01086.12 EKE39185.1 - 0.23 11.3 10.0 0.27 11.1 6.9 1.1 1 0 0 1 1 1 0 Clathrin light chain DUF2316 PF10078.4 EKE39185.1 - 0.25 11.3 1.6 0.64 10.0 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF4407 PF14362.1 EKE39185.1 - 1.2 8.0 8.7 1.4 7.7 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Toxin_56 PF15534.1 EKE39185.1 - 1.6 9.2 8.4 0.42 11.1 2.6 2.1 2 0 0 2 2 2 0 Putative toxin 56 DDHD PF02862.12 EKE39185.1 - 2.5 7.8 8.6 2.5 7.8 6.0 1.0 1 0 0 1 1 1 0 DDHD domain Ydc2-catalyt PF09159.5 EKE39185.1 - 2.8 7.3 10.8 3.3 7.1 7.5 1.0 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 DUF2924 PF11149.3 EKE39185.1 - 2.9 7.9 6.6 4.8 7.1 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Seryl_tRNA_N PF02403.17 EKE39185.1 - 4.9 7.2 21.5 17 5.4 14.9 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF349 PF03993.7 EKE39185.1 - 7.5 6.7 17.2 0.59 10.3 8.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Cyclin_N PF00134.18 EKE39187.1 - 4e-26 91.0 1.7 1.1e-25 89.6 0.4 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EKE39187.1 - 7.6e-24 83.9 0.7 7.6e-24 83.9 0.5 2.1 3 0 0 3 3 3 1 Cyclin, C-terminal domain Herpes_UL37_1 PF03970.8 EKE39187.1 - 0.0025 16.6 1.1 0.0041 15.9 0.7 1.3 1 0 0 1 1 1 1 Herpesvirus UL37 tegument protein Taeniidae_ag PF05596.6 EKE39188.1 - 0.061 13.1 0.5 7.5 6.4 0.1 3.0 2 0 0 2 2 2 0 Taeniidae antigen Mak16 PF04874.9 EKE39188.1 - 0.097 12.7 1.2 0.22 11.6 0.9 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region zf-CCHC PF00098.18 EKE39189.1 - 4.7e-19 67.3 23.8 1e-06 28.3 2.2 3.6 3 0 0 3 3 3 3 Zinc knuckle RRM_1 PF00076.17 EKE39189.1 - 8.5e-10 38.1 0.1 1.9e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39189.1 - 4e-07 29.9 0.0 7.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 EKE39189.1 - 1.5e-05 24.5 15.4 0.059 13.0 0.4 3.9 3 0 0 3 3 3 3 Zinc knuckle RRM_5 PF13893.1 EKE39189.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_2 PF13240.1 EKE39189.1 - 0.11 12.0 9.9 0.8 9.2 0.5 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-CCHC_3 PF13917.1 EKE39189.1 - 0.16 11.7 16.2 0.42 10.3 0.8 3.6 2 1 1 3 3 3 0 Zinc knuckle IBR PF01485.16 EKE39189.1 - 0.79 9.6 15.4 10 6.0 1.7 3.9 2 1 1 3 3 3 0 IBR domain zf-ribbon_3 PF13248.1 EKE39189.1 - 4.1 6.7 14.7 2.3 7.5 5.4 3.0 2 1 1 3 3 3 0 zinc-ribbon domain Alpha-amylase PF00128.19 EKE39190.1 - 5.3e-49 167.3 1.4 1.7e-35 122.9 0.2 3.1 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Peptidase_C54 PF03416.14 EKE39191.1 - 2.6e-22 79.2 0.0 8.9e-16 57.8 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 Peptidase_C78 PF07910.8 EKE39191.1 - 1.5e-05 24.2 0.0 0.00051 19.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C78 Flavin_Reduct PF01613.13 EKE39192.1 - 3e-14 53.1 0.0 3.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF1632 PF07857.7 EKE39193.1 - 2.2e-66 223.7 9.5 2.9e-47 161.0 2.9 2.3 1 1 1 2 2 2 2 CEO family (DUF1632) Sugar_transport PF06800.7 EKE39193.1 - 5.3e-11 42.1 20.4 2.1e-08 33.5 1.7 2.7 3 0 0 3 3 3 2 Sugar transport protein TP53IP5 PF15331.1 EKE39193.1 - 0.019 14.8 3.7 0.027 14.3 2.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 AIF-MLS PF14962.1 EKE39193.1 - 0.65 9.6 2.9 1.1 8.9 2.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF606 PF04657.8 EKE39193.1 - 2.7 8.0 18.0 0.022 14.8 4.7 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF606 AlaDh_PNT_N PF05222.10 EKE39194.1 - 1.2e-06 28.5 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Flavodoxin_5 PF12724.2 EKE39195.1 - 1.1e-06 28.7 0.1 0.0037 17.2 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_4 PF12682.2 EKE39195.1 - 0.00013 21.3 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_1 PF00258.20 EKE39195.1 - 0.014 15.3 0.4 3.3 7.7 0.0 3.0 2 2 0 3 3 3 0 Flavodoxin Flavodoxin_2 PF02525.12 EKE39195.1 - 0.017 14.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold FMN_red PF03358.10 EKE39195.1 - 0.087 12.3 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Actin PF00022.14 EKE39196.1 - 7.1e-11 41.1 0.1 5.4e-06 25.0 0.0 2.5 1 1 1 2 2 2 2 Actin zf-DHHC PF01529.15 EKE39197.1 - 4.8e-37 127.0 13.9 4.8e-37 127.0 9.6 2.2 1 1 1 2 2 2 2 DHHC palmitoyltransferase NnrU PF07298.6 EKE39197.1 - 0.029 13.7 1.7 1.1 8.5 0.3 2.2 2 0 0 2 2 2 0 NnrU protein Imm10 PF15562.1 EKE39197.1 - 0.23 11.2 0.1 0.23 11.2 0.0 3.7 4 0 0 4 4 4 0 Immunity protein 10 DUF4182 PF13790.1 EKE39197.1 - 3.1 7.6 8.3 4.3 7.2 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) Acetyltransf_1 PF00583.19 EKE39198.1 - 1.9e-10 40.6 0.0 2e-10 40.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE39198.1 - 7.1e-05 22.8 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE39198.1 - 0.00071 19.6 0.0 0.00086 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UTP15_C PF09384.5 EKE39199.1 - 2.3e-33 114.9 1.1 3.4e-33 114.4 0.8 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EKE39199.1 - 1.7e-29 100.5 11.2 9e-06 25.3 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EKE39199.1 - 0.00024 20.8 1.0 0.0015 18.2 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Tic20 PF09685.5 EKE39200.1 - 0.0016 18.4 8.6 0.002 18.0 5.9 1.2 1 0 0 1 1 1 1 Tic20-like protein CRT-like PF08627.5 EKE39201.1 - 0.0028 17.5 0.9 0.0035 17.2 0.6 1.1 1 0 0 1 1 1 1 CRT-like DUF1764 PF08576.5 EKE39202.1 - 1e-19 71.1 14.4 1.9e-19 70.3 9.6 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) DUF2413 PF10310.4 EKE39202.1 - 0.047 12.5 9.1 0.054 12.2 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MRP-S31 PF15433.1 EKE39202.1 - 0.055 12.8 5.7 0.063 12.6 4.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Nop14 PF04147.7 EKE39202.1 - 0.062 11.2 11.7 0.073 10.9 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.12 EKE39202.1 - 0.96 9.1 7.3 1.1 9.0 5.1 1.0 1 0 0 1 1 1 0 DDHD domain DUF4071 PF13281.1 EKE39202.1 - 1.2 7.9 4.3 1.4 7.7 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) FlxA PF14282.1 EKE39202.1 - 1.5 8.8 10.2 1.9 8.4 7.1 1.2 1 0 0 1 1 1 0 FlxA-like protein Sec62 PF03839.11 EKE39202.1 - 3.7 6.8 15.3 4.7 6.5 10.6 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.3 EKE39202.1 - 4.4 5.9 11.4 5 5.7 7.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ras PF00071.17 EKE39203.1 - 1.6e-29 102.4 0.2 1.9e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39203.1 - 2.3e-18 66.8 0.1 3e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EKE39203.1 - 0.01 14.9 0.1 0.013 14.5 0.1 1.3 1 1 0 1 1 1 0 AIG1 family AAA_24 PF13479.1 EKE39203.1 - 0.033 13.7 0.1 0.092 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EKE39203.1 - 0.046 12.9 0.1 0.071 12.3 0.1 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family IstB_IS21 PF01695.12 EKE39203.1 - 0.095 12.1 0.0 0.24 10.7 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EKE39203.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EKE39204.1 - 0.062 13.6 17.3 0.075 13.3 12.0 1.1 1 0 0 1 1 1 0 AAA domain UPF0081 PF03652.10 EKE39204.1 - 0.39 10.8 8.1 0.52 10.4 5.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0081) SprA-related PF12118.3 EKE39204.1 - 0.93 8.7 12.8 1.2 8.4 8.8 1.0 1 0 0 1 1 1 0 SprA-related family DUF3897 PF13036.1 EKE39204.1 - 2.7 7.5 9.0 1.2 8.7 4.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3897) Ribosomal_L34 PF00468.12 EKE39204.1 - 5.6 6.7 6.4 2.5 7.8 1.9 2.3 2 1 0 2 2 2 0 Ribosomal protein L34 Vfa1 PF08432.5 EKE39204.1 - 7 6.6 21.6 11 6.0 15.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rap_GAP PF02145.10 EKE39206.1 - 6.3e-06 25.6 0.0 3.5e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Rap/ran-GAP DOCK-C2 PF14429.1 EKE39207.1 - 3.7e-33 114.7 4.2 3.7e-33 114.7 2.9 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EKE39207.1 - 8.7e-26 90.2 0.5 8.2e-25 87.1 0.3 2.8 1 0 0 1 1 1 1 Dedicator of cytokinesis PAP2 PF01569.16 EKE39208.1 - 0.00082 19.0 3.4 0.00082 19.0 2.4 1.8 1 1 1 2 2 2 1 PAP2 superfamily DUF360 PF04020.8 EKE39208.1 - 0.057 13.7 7.2 0.069 13.5 5.0 1.2 1 0 0 1 1 1 0 Membrane protein of unknown function FUSC PF04632.7 EKE39208.1 - 0.11 10.8 0.8 0.13 10.6 0.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family UbiA PF01040.13 EKE39208.1 - 0.39 9.9 9.2 0.47 9.6 6.4 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Polysacc_synt_C PF14667.1 EKE39208.1 - 1.5 8.6 13.1 11 5.8 9.0 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain FAM60A PF15396.1 EKE39209.1 - 6.7 6.3 12.7 8 6.1 8.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CT47 PF15623.1 EKE39209.1 - 7.2 6.2 29.3 12 5.5 20.3 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 C1_1 PF00130.17 EKE39210.1 - 0.071 12.8 6.7 0.17 11.6 4.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CENP-F_leu_zip PF10473.4 EKE39210.1 - 0.67 9.8 34.9 0.093 12.5 13.5 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EKE39210.1 - 2.7 7.7 40.6 0.54 10.0 9.4 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 EKE39210.1 - 6.2 6.5 27.6 0.084 12.6 9.3 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) FAR1 PF03101.10 EKE39211.1 - 8.4e-08 32.6 3.6 2.3e-07 31.2 2.5 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EKE39211.1 - 3e-07 30.6 2.4 6.7e-07 29.4 1.7 1.6 1 0 0 1 1 1 1 Transcription factor AFT DUF4558 PF15104.1 EKE39211.1 - 0.14 12.0 0.8 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) GCC2_GCC3 PF07699.8 EKE39212.1 - 7.2e-52 172.7 134.7 5.3e-09 35.5 3.8 13.4 2 1 14 16 16 16 15 GCC2 and GCC3 NCD3G PF07562.9 EKE39212.1 - 2.4e-21 75.1 91.4 0.002 17.8 3.5 11.3 3 3 3 11 11 11 10 Nine Cysteines Domain of family 3 GPCR VSP PF03302.8 EKE39212.1 - 1.7e-10 40.1 78.4 9e-05 21.2 13.9 4.8 1 1 3 4 4 4 4 Giardia variant-specific surface protein TNFR_c6 PF00020.13 EKE39212.1 - 2e-07 30.9 98.5 0.11 12.6 0.9 14.4 4 3 11 16 16 16 11 TNFR/NGFR cysteine-rich region DUF912 PF06024.7 EKE39212.1 - 0.0032 17.4 0.8 0.018 15.0 0.5 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) ATP-synt_8 PF00895.15 EKE39212.1 - 2.6 8.3 3.6 29 4.9 1.5 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 zf-C3HC4_2 PF13923.1 EKE39213.1 - 2.7e-07 30.4 13.7 5.2e-07 29.5 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE39213.1 - 3.4e-07 29.8 10.0 6.2e-07 29.0 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKE39213.1 - 4.9e-06 26.2 13.8 1.1e-05 25.2 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKE39213.1 - 0.00011 21.7 10.8 0.00022 20.7 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE39213.1 - 0.00021 21.1 11.6 0.00028 20.6 6.9 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EKE39213.1 - 0.00027 20.5 9.3 0.00046 19.7 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKE39213.1 - 0.0071 16.0 5.4 0.011 15.3 2.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-H2C2_2 PF13465.1 EKE39213.1 - 0.22 11.8 5.3 4.9 7.6 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Presenilin PF01080.12 EKE39213.1 - 2.1 7.0 6.8 0.36 9.5 1.4 1.9 2 0 0 2 2 2 0 Presenilin DUF1764 PF08576.5 EKE39213.1 - 5.4 7.8 13.9 11 6.8 3.0 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Las1 PF04031.8 EKE39214.1 - 7.9e-26 90.5 0.0 1.6e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Las1-like DUF1198 PF06711.6 EKE39214.1 - 0.033 13.9 0.2 0.9 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Pkinase_Tyr PF07714.12 EKE39216.1 - 1.5e-23 83.1 0.0 6.5e-23 81.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39216.1 - 7.6e-18 64.5 0.1 9.7e-17 60.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.1 EKE39217.1 - 0.00039 20.1 0.6 0.00039 20.1 0.4 2.6 3 0 0 3 3 3 1 TMEM154 protein family DUF3328 PF11807.3 EKE39217.1 - 0.052 13.2 0.9 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Rifin_STEVOR PF02009.11 EKE39217.1 - 0.16 11.5 1.2 0.18 11.4 0.2 1.6 2 0 0 2 2 2 0 Rifin/stevor family HLH PF00010.21 EKE39218.1 - 0.012 15.2 0.2 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Metallophos PF00149.23 EKE39219.1 - 1.3e-06 27.9 0.2 1.9e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HD PF01966.17 EKE39221.1 - 1.5e-15 57.3 0.8 3.1e-15 56.2 0.5 1.6 1 0 0 1 1 1 1 HD domain Pyr_redox_2 PF07992.9 EKE39222.1 - 6e-11 42.5 0.3 1.2e-06 28.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKE39222.1 - 7.6e-09 35.8 0.2 1.6e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKE39222.1 - 0.026 13.3 1.7 0.14 10.9 0.0 2.3 1 1 1 3 3 3 0 FAD binding domain CPSase_L_chain PF00289.17 EKE39222.1 - 0.041 13.9 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain AlaDh_PNT_C PF01262.16 EKE39222.1 - 0.044 13.3 0.3 0.081 12.4 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PA PF02225.17 EKE39222.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 PA domain CofC PF01983.11 EKE39223.1 - 0.00052 19.0 0.6 0.0007 18.6 0.4 1.2 1 0 0 1 1 1 1 Guanylyl transferase CofC like Carbpep_Y_N PF05388.6 EKE39223.1 - 0.091 12.9 2.2 0.36 10.9 0.5 2.0 1 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide DUF1977 PF09320.6 EKE39223.1 - 1.7 8.9 6.6 0.37 11.0 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) PI3_PI4_kinase PF00454.22 EKE39224.1 - 1.8e-17 63.5 2.3 5.2e-17 62.1 1.6 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase C1_1 PF00130.17 EKE39225.1 - 5.3e-12 45.2 54.8 8.7e-07 28.5 8.1 4.5 4 0 0 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_acc PF00609.14 EKE39225.1 - 1.2e-06 28.7 1.1 4.1e-06 27.0 0.1 2.3 2 1 0 2 2 2 1 Diacylglycerol kinase accessory domain PHD PF00628.24 EKE39225.1 - 0.0013 18.4 7.9 0.0013 18.4 5.5 4.3 4 1 0 4 4 4 2 PHD-finger LRR_5 PF13306.1 EKE39226.1 - 7.7e-38 129.1 15.6 1.4e-22 79.7 2.8 2.6 2 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE39226.1 - 2e-13 49.8 3.8 5.8e-06 25.9 0.1 4.3 2 1 2 4 4 4 4 Leucine rich repeat Scm3 PF10384.4 EKE39227.1 - 0.0017 17.7 1.9 0.0044 16.4 1.3 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Pinin_SDK_memA PF04696.8 EKE39228.1 - 0.56 9.8 7.8 1.3 8.6 5.3 1.8 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region RasGEF PF00617.14 EKE39229.1 - 1.5e-42 145.4 3.6 1.5e-42 145.4 2.5 3.0 2 1 1 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 EKE39229.1 - 6.6e-08 32.5 0.0 3.2e-07 30.4 0.0 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif RRM_1 PF00076.17 EKE39230.1 - 0.0065 16.0 1.0 0.031 13.9 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfatase_C PF14707.1 EKE39230.1 - 0.037 14.3 0.6 0.4 10.9 0.1 2.5 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase HCR PF07111.7 EKE39230.1 - 0.048 11.6 2.3 0.097 10.6 1.6 1.4 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF3508 PF12018.3 EKE39230.1 - 0.74 8.7 12.9 0.041 12.8 5.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) Peptidase_C65 PF10275.4 EKE39230.1 - 5.2 6.3 15.6 0.99 8.7 6.5 2.1 2 0 0 2 2 2 0 Peptidase C65 Otubain DUF4250 PF14056.1 EKE39231.1 - 0.84 9.4 3.1 41 4.0 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Ribosomal_S14 PF00253.16 EKE39232.1 - 1e-17 63.2 4.4 1.1e-17 63.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DZR PF12773.2 EKE39232.1 - 0.14 11.9 1.1 0.21 11.4 0.8 1.3 1 1 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EKE39232.1 - 0.16 12.0 1.9 0.33 11.0 0.2 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase ZZ PF00569.12 EKE39232.1 - 0.55 9.8 3.0 2.9 7.4 2.1 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type Ribosomal_L40e PF01020.12 EKE39232.1 - 0.79 9.3 5.8 3.7 7.2 0.3 2.1 1 1 1 2 2 2 0 Ribosomal L40e family IF4E PF01652.13 EKE39234.1 - 2.6e-24 85.6 1.0 3.1e-24 85.3 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TLD PF07534.11 EKE39236.1 - 1.3e-29 103.0 0.2 2.6e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 TLD BSD PF03909.12 EKE39236.1 - 5.5e-07 29.2 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 BSD domain EF-hand_7 PF13499.1 EKE39237.1 - 1.1e-24 86.3 5.2 2.4e-12 46.7 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EKE39237.1 - 4.1e-23 78.8 11.0 7.3e-08 31.1 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EKE39237.1 - 7.9e-22 75.1 6.9 3.1e-08 32.8 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EKE39237.1 - 3.5e-13 48.2 3.9 3.8e-06 25.9 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EKE39237.1 - 8.4e-12 44.5 6.7 9e-06 25.2 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EKE39237.1 - 9.4e-11 41.4 0.2 0.00041 20.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EKE39237.1 - 4.3e-05 23.1 2.5 0.00082 19.0 0.2 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EKE39237.1 - 0.0002 20.8 0.0 0.44 10.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EKE39237.1 - 0.00026 20.8 4.0 0.0039 17.1 0.1 2.6 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 EKE39237.1 - 0.00086 19.3 0.8 0.65 10.0 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.4 EKE39237.1 - 0.0037 17.3 0.1 0.31 11.1 0.1 2.3 1 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) EF-hand_like PF09279.6 EKE39237.1 - 0.0091 15.9 2.9 1.9 8.5 0.1 3.1 2 2 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like PRESAN PF09687.5 EKE39237.1 - 0.017 15.1 0.5 0.27 11.2 0.4 2.5 1 1 0 1 1 1 0 Plasmodium RESA N-terminal DUF2341 PF10102.4 EKE39237.1 - 0.082 13.0 1.4 1.8 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) EF-hand_10 PF14788.1 EKE39237.1 - 0.094 12.3 4.8 19 5.0 0.0 3.8 4 0 0 4 4 4 0 EF hand GTPase_Cys_C PF12631.2 EKE39237.1 - 0.15 12.5 1.7 4.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Herpes_UL6 PF01763.11 EKE39237.1 - 0.28 9.2 2.5 0.35 8.9 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like RNA_pol_Rpb4 PF03874.11 EKE39237.1 - 2.3 8.2 5.6 5.2 7.0 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 AA_permease_2 PF13520.1 EKE39238.1 - 2.2e-33 115.4 42.2 3.4e-33 114.8 29.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKE39238.1 - 4.9e-18 64.7 36.6 7.1e-18 64.2 25.4 1.1 1 0 0 1 1 1 1 Amino acid permease Rap_GAP PF02145.10 EKE39239.1 - 9.5e-48 162.0 2.4 1.7e-46 157.9 0.1 2.5 2 0 0 2 2 2 2 Rap/ran-GAP DUF3397 PF11877.3 EKE39240.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) Ins134_P3_kin PF05770.6 EKE39241.1 - 5.9e-35 120.7 0.7 1.3e-34 119.6 0.5 1.5 1 1 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase RimK PF08443.6 EKE39241.1 - 5.9e-06 25.8 0.2 0.096 12.1 0.1 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 EKE39241.1 - 7.5e-05 22.5 0.0 0.004 16.9 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKE39241.1 - 0.046 12.4 0.0 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ABC_tran PF00005.22 EKE39242.1 - 2.3e-51 173.6 0.2 9.6e-28 97.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKE39242.1 - 1.6e-40 139.2 66.8 5.3e-24 85.0 12.9 3.6 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EKE39242.1 - 1.1e-08 34.5 4.4 0.024 13.8 0.5 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.20 EKE39242.1 - 0.00013 21.5 0.7 0.024 14.1 0.0 3.0 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 EKE39242.1 - 0.0006 19.8 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EKE39242.1 - 0.00087 19.2 0.1 0.56 10.1 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE39242.1 - 0.0015 18.6 0.4 3.5 7.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EKE39242.1 - 0.0056 17.1 0.5 5.9 7.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 EKE39242.1 - 0.0085 15.9 2.2 0.056 13.2 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 EKE39242.1 - 0.0087 15.2 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKE39242.1 - 0.035 13.5 0.1 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EKE39242.1 - 0.042 13.4 0.8 0.25 10.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EKE39242.1 - 0.05 13.1 0.5 0.78 9.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EKE39242.1 - 0.085 13.1 5.4 7.1 6.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EKE39242.1 - 0.17 11.4 0.3 2.1 7.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Metallophos PF00149.23 EKE39243.1 - 1.9e-32 112.3 0.3 3.4e-32 111.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_25 PF01183.15 EKE39244.1 - 1.2e-10 41.5 3.4 1.4e-10 41.3 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RRM_6 PF14259.1 EKE39245.1 - 1e-09 38.2 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE39245.1 - 1.7e-05 24.3 0.0 5.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39245.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_2 PF07716.10 EKE39246.1 - 1.7e-06 27.7 13.2 1.7e-06 27.7 9.1 3.4 2 2 1 3 3 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EKE39246.1 - 2.6e-05 24.1 19.0 2.6e-05 24.1 13.2 3.3 3 1 0 3 3 3 1 bZIP transcription factor AAA_27 PF13514.1 EKE39246.1 - 0.031 12.0 10.4 0.037 11.7 7.2 1.0 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EKE39246.1 - 0.032 13.7 1.5 0.039 13.5 0.3 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family bZIP_Maf PF03131.12 EKE39246.1 - 0.038 14.2 17.0 0.027 14.7 9.9 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor DegS PF05384.6 EKE39246.1 - 0.095 11.9 12.9 0.15 11.2 9.0 1.3 1 1 0 1 1 1 0 Sensor protein DegS ORF6C PF10552.4 EKE39246.1 - 0.42 10.3 11.1 3.2 7.4 1.5 2.1 1 1 1 2 2 2 0 ORF6C domain DUF1411 PF07199.6 EKE39246.1 - 0.49 9.8 3.4 0.26 10.6 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) DUF342 PF03961.8 EKE39246.1 - 1 7.6 14.6 1.2 7.4 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 EKE39246.1 - 1.6 8.2 21.7 1.6 8.2 3.0 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CDC37_C PF08564.5 EKE39246.1 - 1.7 8.5 8.8 0.41 10.5 3.4 1.9 1 1 1 2 2 2 0 Cdc37 C terminal domain FlaC_arch PF05377.6 EKE39246.1 - 2.3 8.1 7.3 3.5 7.5 0.7 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2536 PF10750.4 EKE39246.1 - 2.7 7.6 5.8 3.9 7.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) APG6 PF04111.7 EKE39246.1 - 5.5 5.9 16.7 8.5 5.3 11.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Uds1 PF15456.1 EKE39246.1 - 5.6 6.9 14.5 12 5.8 10.0 1.6 1 1 1 2 2 2 0 Up-regulated During Septation DUF4047 PF13256.1 EKE39246.1 - 7.2 6.5 9.4 6.8 6.6 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DUF4404 PF14357.1 EKE39246.1 - 9.4 6.7 8.2 3.3 8.1 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) adh_short PF00106.20 EKE39247.1 - 7.8e-20 71.4 0.0 9.7e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EKE39247.1 - 2e-06 27.4 0.2 4e-06 26.4 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKE39247.1 - 2.1e-05 24.2 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EKE39247.1 - 0.0077 15.1 0.2 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ApbA PF02558.11 EKE39247.1 - 0.0096 15.3 1.3 0.27 10.6 0.9 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.1 EKE39247.1 - 0.011 15.5 0.2 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKE39247.1 - 0.022 14.7 0.0 0.07 13.1 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding DUF1863 PF08937.6 EKE39247.1 - 0.077 13.0 1.7 3.5 7.6 0.1 2.4 1 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) DUF1776 PF08643.5 EKE39247.1 - 0.12 11.4 5.7 0.5 9.4 4.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) TFIID_20kDa PF03847.8 EKE39248.1 - 1.8e-08 34.5 0.5 2.7e-08 33.9 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.11 EKE39248.1 - 0.074 12.8 0.1 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit SapB_1 PF05184.10 EKE39249.1 - 0.014 15.2 1.1 0.014 15.2 0.8 2.6 3 0 0 3 3 3 0 Saposin-like type B, region 1 Cullin PF00888.17 EKE39250.1 - 1.6e-58 198.7 24.6 1.6e-58 198.7 17.0 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EKE39250.1 - 3e-20 71.7 5.6 3e-20 71.7 3.9 3.5 4 0 0 4 4 4 1 Cullin protein neddylation domain RNA_bind PF08675.6 EKE39250.1 - 0.07 13.1 0.8 0.23 11.4 0.2 2.2 1 1 1 2 2 2 0 RNA binding domain Tubulin PF00091.20 EKE39251.1 - 2.4e-10 40.6 0.3 2.4e-10 40.6 0.2 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain ABC2_membrane_3 PF12698.2 EKE39252.1 - 0.097 11.6 1.4 0.15 11.0 1.0 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF883 PF05957.8 EKE39254.1 - 0.19 12.1 6.4 0.98 9.8 0.1 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YccV-like PF08755.6 EKE39255.1 - 0.041 13.8 2.2 0.041 13.8 1.5 1.8 1 1 1 2 2 2 0 Hemimethylated DNA-binding protein YccV like alpha-hel2 PF14456.1 EKE39255.1 - 0.091 11.5 3.7 0.1 11.3 2.5 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 Imm46 PF15585.1 EKE39255.1 - 0.49 10.4 3.6 0.58 10.2 2.5 1.2 1 0 0 1 1 1 0 Immunity protein 46 IncA PF04156.9 EKE39255.1 - 0.63 9.6 16.1 0.83 9.2 11.2 1.1 1 0 0 1 1 1 0 IncA protein DUF3347 PF11827.3 EKE39255.1 - 0.84 9.6 9.9 0.88 9.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF503 PF04456.7 EKE39255.1 - 1.2 8.8 9.1 0.21 11.2 2.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF503) Glycohydro_20b2 PF14845.1 EKE39255.1 - 1.2 9.7 5.3 1.5 9.4 3.6 1.1 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like DUF2265 PF10023.4 EKE39255.1 - 1.5 7.8 10.6 1.7 7.7 7.4 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) AKAP95 PF04988.7 EKE39255.1 - 1.9 8.2 13.0 3.2 7.5 8.9 1.4 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) CorA PF01544.13 EKE39255.1 - 2.4 7.0 6.4 2.8 6.9 4.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Atg14 PF10186.4 EKE39255.1 - 5 5.9 22.4 5.9 5.7 15.5 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fumble PF03630.9 EKE39255.1 - 6.3 5.5 8.9 7.1 5.3 6.2 1.0 1 0 0 1 1 1 0 Fumble DUF3287 PF11690.3 EKE39255.1 - 7.8 6.6 12.4 16 5.5 8.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) DUF2252 PF10009.4 EKE39255.1 - 8.3 5.1 10.4 9.2 5.0 7.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) ALMT PF11744.3 EKE39255.1 - 8.4 4.9 8.1 9.6 4.7 5.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter ANTH PF07651.11 EKE39256.1 - 3.2e-22 78.5 0.1 3.2e-22 78.5 0.1 3.5 4 1 0 4 4 4 1 ANTH domain I_LWEQ PF01608.12 EKE39256.1 - 1.2e-16 61.0 6.6 1.2e-16 61.0 4.6 1.8 2 0 0 2 2 2 1 I/LWEQ domain DUF3538 PF12057.3 EKE39256.1 - 0.2 11.2 4.3 2.4 7.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3538) Sec7 PF01369.15 EKE39257.1 - 1.2e-23 83.8 0.0 3.9e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EKE39257.1 - 1.5e-09 37.4 2.8 1.5e-09 37.4 1.9 3.6 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EKE39257.1 - 0.00092 18.6 0.7 0.1 12.1 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) zf-MYND PF01753.13 EKE39257.1 - 0.0012 18.6 11.2 0.0028 17.5 7.7 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EKE39257.1 - 5.7 6.6 13.0 18 5.0 9.0 1.9 1 1 0 1 1 1 0 HIT zinc finger Cation_efflux PF01545.16 EKE39258.1 - 3.3e-67 226.5 7.7 3.3e-67 226.5 5.3 1.9 2 1 0 2 2 2 1 Cation efflux family NT-C2 PF10358.4 EKE39259.1 - 0.0088 15.5 7.2 0.0088 15.5 5.0 2.3 2 1 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3456 PF11938.3 EKE39259.1 - 0.37 10.7 4.4 0.47 10.4 0.2 2.9 3 1 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP Ribosomal_S10 PF00338.17 EKE39260.1 - 2e-28 98.0 0.4 2.5e-28 97.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1922 PF09082.5 EKE39260.1 - 0.12 12.4 0.2 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) WHG PF13305.1 EKE39261.1 - 1.3 9.6 4.0 3.7 8.1 0.1 2.7 2 1 0 2 2 2 0 WHG domain Cyt_c_ox_IV PF12270.3 EKE39261.1 - 2.1 8.1 8.0 0.86 9.3 2.6 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV PRA1 PF03208.14 EKE39261.1 - 4.6 6.5 9.3 7.7 5.8 6.4 1.4 1 0 0 1 1 1 0 PRA1 family protein adh_short PF00106.20 EKE39262.1 - 9.7e-13 48.3 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKE39262.1 - 6.9e-06 25.8 0.0 9.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKE39262.1 - 2.5e-05 24.1 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKE39262.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.9 EKE39262.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EF1_GNE PF00736.14 EKE39263.1 - 1.2e-28 98.6 0.9 1.9e-28 97.9 0.6 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain C2 PF00168.25 EKE39264.1 - 1.1e-36 124.5 8.1 2.6e-21 75.2 0.1 3.3 3 0 0 3 3 3 2 C2 domain XYPPX PF02162.12 EKE39264.1 - 0.56 9.8 101.0 0.093 12.3 6.9 8.5 7 1 1 8 8 8 0 XYPPX repeat (two copies) GBP PF02263.14 EKE39265.1 - 1.9e-30 105.8 2.1 1.9e-30 105.8 1.4 2.2 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EKE39265.1 - 0.0024 17.8 0.0 0.0024 17.8 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EKE39265.1 - 0.31 11.8 3.9 5.8 7.7 0.0 3.8 3 1 0 4 4 4 0 AAA domain DUF1411 PF07199.6 EKE39266.1 - 0.063 12.7 0.1 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) DUF3992 PF13157.1 EKE39266.1 - 0.51 10.5 4.8 0.9 9.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Glycos_transf_1 PF00534.15 EKE39267.1 - 7.2e-25 87.3 0.7 1.2e-24 86.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EKE39267.1 - 3.7e-11 43.3 0.0 9.7e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EKE39267.1 - 2.1e-05 24.6 0.0 5.5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 PRP1_N PF06424.7 EKE39268.1 - 1.7e-21 76.9 12.6 2.8e-20 72.9 8.7 2.5 1 1 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EKE39268.1 - 1.1e-13 50.5 0.0 0.21 12.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKE39268.1 - 1.8e-13 49.8 3.7 0.0035 16.9 0.0 5.5 5 1 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 EKE39268.1 - 3.2e-08 32.8 0.6 0.0095 15.7 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKE39268.1 - 6.8e-08 32.7 0.0 0.33 11.3 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKE39268.1 - 1.5e-05 25.4 0.0 2.6 8.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EKE39268.1 - 4.8e-05 22.5 0.0 0.12 11.3 0.0 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKE39268.1 - 7.1e-05 22.2 1.8 0.043 13.4 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKE39268.1 - 0.00012 21.9 0.1 0.44 10.5 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKE39268.1 - 0.00056 19.9 0.5 45 4.6 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKE39268.1 - 0.00073 19.1 10.8 1.8 8.5 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat Peptidase_C1 PF00112.18 EKE39269.1 - 9.7e-06 25.6 1.7 0.085 12.7 0.2 2.7 2 1 0 2 2 2 2 Papain family cysteine protease VSP PF03302.8 EKE39270.1 - 6.6e-14 51.3 134.8 6.9e-07 28.2 26.3 5.2 1 1 3 4 4 4 3 Giardia variant-specific surface protein zf-UBR PF02207.15 EKE39271.1 - 1e-17 63.5 16.5 1e-17 63.5 11.5 3.8 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-rbx1 PF12678.2 EKE39271.1 - 4.7e-05 23.4 1.3 4.7e-05 23.4 0.9 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EKE39271.1 - 0.00018 21.2 1.7 0.00018 21.2 1.1 4.4 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EKE39271.1 - 0.0027 17.3 1.5 0.0027 17.3 1.1 4.8 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE39271.1 - 0.0074 16.2 2.9 0.0074 16.2 2.0 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Aminotran_5 PF00266.14 EKE39272.1 - 4.6e-47 160.5 0.0 6.7e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V zf-C2H2_jaz PF12171.3 EKE39273.1 - 0.0016 18.5 1.6 0.0016 18.5 1.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EKE39273.1 - 0.0019 18.4 1.5 0.0019 18.4 1.0 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type G-patch_2 PF12656.2 EKE39273.1 - 0.0085 15.9 1.4 0.027 14.3 0.0 2.6 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 EKE39273.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 G-patch domain zf-C2H2_4 PF13894.1 EKE39273.1 - 0.088 13.1 0.6 0.088 13.1 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EKE39273.1 - 0.089 13.0 1.1 0.21 11.8 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EKE39273.1 - 0.2 12.0 2.9 25 5.4 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_L19e PF01280.15 EKE39274.1 - 8e-45 152.2 7.6 1.2e-44 151.6 5.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19e CorA PF01544.13 EKE39275.1 - 3.9e-49 167.2 4.4 5.3e-49 166.8 3.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SWIRM PF04433.12 EKE39276.1 - 4.3e-22 78.0 0.5 9.7e-22 76.9 0.3 1.6 1 0 0 1 1 1 1 SWIRM domain RasGEF PF00617.14 EKE39277.1 - 5.6e-43 146.8 2.0 8e-43 146.3 0.1 2.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 EKE39277.1 - 1.8e-12 47.2 3.8 2.7e-12 46.7 0.1 3.1 4 0 0 4 4 4 1 RasGEF N-terminal motif IncA PF04156.9 EKE39277.1 - 5.9 6.4 17.0 17 4.9 8.1 2.7 2 0 0 2 2 2 0 IncA protein PsbJ PF01788.12 EKE39278.1 - 0.068 12.7 1.0 0.23 11.0 0.7 1.9 1 0 0 1 1 1 0 PsbJ TraS PF10624.4 EKE39278.1 - 4.5 6.8 8.9 0.12 11.8 1.4 1.9 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS TLD PF07534.11 EKE39280.1 - 8.9e-11 41.9 1.2 1.5e-10 41.1 0.8 1.3 1 0 0 1 1 1 1 TLD PAP2_C PF14360.1 EKE39281.1 - 1.2e-11 44.7 15.4 1.2e-11 44.7 10.7 3.7 3 1 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EKE39281.1 - 0.014 15.0 21.5 0.11 12.1 14.8 2.4 1 1 0 1 1 1 0 PAP2 superfamily NtA PF03146.10 EKE39282.1 - 0.091 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Agrin NtA domain Peptidase_S74 PF13884.1 EKE39284.1 - 7.7e-15 54.7 0.1 2.1e-14 53.3 0.1 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase YL1 PF05764.8 EKE39285.1 - 0.004 16.7 18.3 0.0047 16.5 12.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Sporozoite_P67 PF05642.6 EKE39285.1 - 0.89 7.3 6.8 1.1 7.0 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.7 EKE39285.1 - 1.4 8.7 14.5 1.9 8.3 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EKE39285.1 - 1.9 6.4 13.8 2.2 6.2 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RNase_H2-Ydr279 PF09468.5 EKE39285.1 - 1.9 7.5 14.1 2.6 7.1 9.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Menin PF05053.8 EKE39285.1 - 3.2 5.8 7.9 3.6 5.6 5.5 1.1 1 0 0 1 1 1 0 Menin Pox_RNA_Pol_19 PF05320.7 EKE39285.1 - 3.4 7.4 11.8 5 6.8 8.2 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HSP70 PF00012.15 EKE39285.1 - 3.9 5.2 9.6 4.8 4.9 6.7 1.1 1 0 0 1 1 1 0 Hsp70 protein Suf PF05843.9 EKE39285.1 - 4.4 6.9 10.4 5.5 6.6 7.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GAGA_bind PF06217.7 EKE39285.1 - 7.6 6.4 13.7 9.2 6.1 9.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family WD40 PF00400.27 EKE39286.1 - 5.2e-19 67.3 18.9 4e-06 26.4 0.0 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EKE39286.1 - 0.0018 18.0 3.2 0.044 13.4 1.1 3.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EKE39286.1 - 0.054 11.3 0.5 1.6 6.4 0.0 2.4 1 1 2 3 3 3 0 IKI3 family DUF1355 PF07090.6 EKE39287.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) RabGAP-TBC PF00566.13 EKE39288.1 - 1.2e-22 80.4 10.1 1.2e-22 80.4 7.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4047 PF13256.1 EKE39288.1 - 0.04 13.8 0.5 0.04 13.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF1505 PF07403.6 EKE39289.1 - 0.027 14.3 1.4 0.027 14.3 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) Sybindin PF04099.7 EKE39290.1 - 0.037 13.7 0.1 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Sybindin-like family DUF2612 PF11041.3 EKE39290.1 - 0.061 12.8 0.2 0.07 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) EF-hand_7 PF13499.1 EKE39291.1 - 4.6e-31 106.7 27.3 1.4e-14 53.9 0.1 7.5 4 4 3 7 7 7 4 EF-hand domain pair EF-hand_1 PF00036.27 EKE39291.1 - 3.3e-15 54.1 23.6 0.0055 15.9 0.0 8.2 9 0 0 9 9 9 5 EF hand EF-hand_6 PF13405.1 EKE39291.1 - 1.6e-11 43.0 26.9 0.042 13.7 0.0 9.6 9 1 1 10 10 10 4 EF-hand domain EF-hand_5 PF13202.1 EKE39291.1 - 5.6e-09 34.9 8.5 0.16 11.4 0.0 5.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EKE39291.1 - 1.6e-07 30.7 16.0 0.016 14.8 0.1 7.2 6 1 1 7 7 7 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKE39291.1 - 0.00014 21.8 6.7 0.042 13.8 0.1 3.9 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Protein_K PF12283.3 EKE39291.1 - 0.011 15.6 0.5 7.5 6.5 0.1 2.9 2 0 0 2 2 2 0 Bacteriophage protein K IMD PF08397.6 EKE39292.1 - 2e-06 27.2 6.4 3.2e-06 26.6 4.2 1.5 1 1 0 1 1 1 1 IRSp53/MIM homology domain WH2 PF02205.15 EKE39292.1 - 0.00069 19.1 0.1 0.0015 18.0 0.1 1.6 1 0 0 1 1 1 1 WH2 motif DUF148 PF02520.12 EKE39292.1 - 0.00096 18.9 1.1 0.00096 18.9 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF148 DUF3584 PF12128.3 EKE39292.1 - 0.015 12.6 3.4 0.02 12.2 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3610 PF12272.3 EKE39292.1 - 0.053 13.1 7.7 0.27 10.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3610) GLTP PF08718.6 EKE39292.1 - 0.51 10.3 6.5 0.055 13.5 0.6 2.3 3 1 0 3 3 3 0 Glycolipid transfer protein (GLTP) zf-CCCH PF00642.19 EKE39293.1 - 2.3e-12 46.2 4.4 9e-06 25.2 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EKE39293.1 - 3.7e-05 23.2 0.1 9.2e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39293.1 - 4.5e-05 23.2 0.1 9.1e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39293.1 - 0.062 13.2 0.1 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Na_Ca_ex PF01699.19 EKE39294.1 - 3.1e-35 120.8 38.8 5.4e-18 64.9 9.2 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein GSHPx PF00255.14 EKE39294.1 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione peroxidase DUF2458 PF10454.4 EKE39294.1 - 0.074 12.9 0.4 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) IBN_N PF03810.14 EKE39295.1 - 1.7e-05 24.6 1.8 9e-05 22.3 0.2 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 EKE39295.1 - 0.032 13.9 6.8 0.025 14.2 0.5 3.8 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Ras PF00071.17 EKE39296.1 - 2.6e-63 212.2 0.1 3.1e-63 211.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39296.1 - 3.9e-20 72.5 0.0 5.6e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39296.1 - 1.1e-15 57.3 0.2 1.3e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39296.1 - 9.5e-09 34.7 0.0 1.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE39296.1 - 1.5e-05 24.5 0.1 5.6e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39296.1 - 1.9e-05 24.5 0.1 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE39296.1 - 0.00019 20.7 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EKE39296.1 - 0.0012 18.3 0.1 0.014 14.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EKE39296.1 - 0.0036 16.4 0.1 0.0051 16.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE39296.1 - 0.0052 16.7 0.1 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKE39296.1 - 0.0056 16.8 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EKE39296.1 - 0.0082 15.4 0.1 0.6 9.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.1 EKE39296.1 - 0.013 15.0 0.2 0.029 13.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EKE39296.1 - 0.016 13.8 5.3 0.64 8.6 0.3 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.9 EKE39296.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.13 EKE39296.1 - 0.03 13.3 0.1 0.066 12.2 0.0 1.5 1 1 0 1 1 1 0 Septin AAA_24 PF13479.1 EKE39296.1 - 0.031 13.8 0.0 0.064 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EKE39296.1 - 0.046 13.2 0.0 1 8.8 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EKE39296.1 - 0.051 13.7 0.0 1.7 8.8 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKE39296.1 - 0.059 13.0 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase MCM PF00493.18 EKE39296.1 - 0.077 11.7 0.1 0.15 10.8 0.0 1.4 2 0 0 2 2 2 0 MCM2/3/5 family ABC_tran PF00005.22 EKE39296.1 - 0.088 13.1 1.4 0.18 12.0 0.9 1.7 1 1 0 1 1 1 0 ABC transporter E2F_TDP PF02319.15 EKE39298.1 - 0.021 14.3 1.0 0.16 11.5 0.0 2.9 3 0 0 3 3 3 0 E2F/DP family winged-helix DNA-binding domain LRR_8 PF13855.1 EKE39299.1 - 0.36 10.6 5.1 0.65 9.8 2.3 2.2 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EKE39299.1 - 1.2 8.7 8.3 0.095 12.3 1.5 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 EKE39300.1 - 6e-74 248.4 0.0 6.8e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39300.1 - 2e-33 115.5 0.0 2.6e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39300.1 - 0.00087 18.3 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EKE39300.1 - 0.0051 15.6 0.0 0.0076 15.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EKE39300.1 - 0.024 13.6 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE39300.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.19 EKE39301.1 - 4.3e-18 65.1 0.1 6.2e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKE39301.1 - 6.2e-14 52.1 0.0 7.3e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKE39301.1 - 1.6e-12 47.3 2.6 2.7e-12 46.6 1.8 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKE39301.1 - 1.1e-06 28.9 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKE39301.1 - 1.6e-06 28.0 0.3 2.1e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKE39301.1 - 9.4e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 EKE39301.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKE39301.1 - 0.00015 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EKE39301.1 - 0.00019 21.4 5.5 0.0003 20.7 3.8 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Skp1 PF01466.14 EKE39303.1 - 6.8e-30 102.9 1.2 6.8e-30 102.9 0.8 1.6 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EKE39303.1 - 1.2e-13 50.9 0.9 2.4e-13 49.9 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Phage_int_SAM_5 PF13102.1 EKE39303.1 - 0.014 15.4 0.5 0.092 12.7 0.0 2.0 2 0 0 2 2 2 0 Phage integrase SAM-like domain DUF615 PF04751.9 EKE39303.1 - 0.13 11.9 0.3 0.33 10.5 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF615) Fn3_assoc PF13287.1 EKE39305.1 - 0.034 14.2 0.6 0.1 12.7 0.4 1.8 1 0 0 1 1 1 0 Fn3 associated Chordopox_A13L PF05961.6 EKE39305.1 - 0.27 11.2 2.6 0.54 10.2 0.8 2.4 2 0 0 2 2 2 0 Chordopoxvirus A13L protein THDPS_N PF14790.1 EKE39306.1 - 0.0016 18.0 2.4 0.11 12.1 0.4 2.4 2 0 0 2 2 2 2 Tetrahydrodipicolinate N-succinyltransferase N-terminal RhoGEF PF00621.15 EKE39307.1 - 7.3e-36 123.7 2.2 7.3e-36 123.7 1.5 2.3 3 1 0 3 3 3 1 RhoGEF domain PI3K_rbd PF00794.13 EKE39308.1 - 1.9e-13 50.2 1.7 1e-10 41.4 0.1 3.6 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain PI3Ka PF00613.15 EKE39308.1 - 5.8e-13 48.4 4.2 2.4e-07 30.1 0.1 2.4 1 1 1 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EKE39308.1 - 8.8e-12 45.0 0.1 7.6e-11 41.9 0.1 2.4 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 Clat_adaptor_s PF01217.15 EKE39308.1 - 0.0015 18.2 0.9 0.0055 16.4 0.1 2.2 2 0 0 2 2 2 1 Clathrin adaptor complex small chain RA PF00788.18 EKE39308.1 - 0.067 13.6 0.0 0.31 11.5 0.0 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Mic1 PF07035.7 EKE39309.1 - 0.17 11.2 1.8 0.27 10.5 0.2 1.8 1 1 1 2 2 2 0 Colon cancer-associated protein Mic1-like Polysacc_deac_1 PF01522.16 EKE39310.1 - 5.3e-16 58.3 0.0 7.3e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase HMG_box_2 PF09011.5 EKE39310.1 - 0.11 12.8 0.2 0.57 10.5 0.0 2.2 2 1 1 3 3 3 0 HMG-box domain Ras PF00071.17 EKE39311.1 - 1.6e-48 164.1 0.0 1.8e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE39311.1 - 3.2e-19 68.8 0.0 3.9e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE39311.1 - 2.5e-18 66.6 0.0 3.4e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE39311.1 - 6.3e-07 29.0 0.1 6.8e-05 22.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE39311.1 - 8.3e-07 28.3 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE39311.1 - 1.1e-06 27.9 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE39311.1 - 1.3e-06 28.3 0.1 2.3e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE39311.1 - 3.2e-06 27.3 0.0 0.00028 21.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKE39311.1 - 2.1e-05 24.0 0.1 0.0006 19.3 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EKE39311.1 - 0.00015 21.9 0.0 0.00042 20.5 0.0 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EKE39311.1 - 0.00019 20.6 0.3 0.00019 20.6 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EKE39311.1 - 0.00025 21.8 0.1 0.00039 21.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE39311.1 - 0.00088 19.5 0.1 0.0018 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE39311.1 - 0.0015 18.2 0.1 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EKE39311.1 - 0.0018 18.4 0.3 0.0068 16.5 0.1 2.2 2 1 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 EKE39311.1 - 0.0032 17.0 0.0 0.0036 16.8 0.0 1.2 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EKE39311.1 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EKE39311.1 - 0.0061 16.2 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 1 NTPase G-alpha PF00503.15 EKE39311.1 - 0.007 15.0 0.3 1.6 7.3 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.1 EKE39311.1 - 0.0078 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Septin PF00735.13 EKE39311.1 - 0.0079 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Septin DUF87 PF01935.12 EKE39311.1 - 0.011 15.6 0.0 0.94 9.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EKE39311.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TRAPPC-Trs85 PF12739.2 EKE39311.1 - 0.019 13.6 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF258 PF03193.11 EKE39311.1 - 0.019 14.1 0.0 0.042 13.0 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EKE39311.1 - 0.022 14.0 0.1 0.084 12.1 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.21 EKE39311.1 - 0.042 13.3 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MCM PF00493.18 EKE39311.1 - 0.054 12.2 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family ABC_tran PF00005.22 EKE39311.1 - 0.057 13.7 0.3 0.069 13.4 0.2 1.4 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EKE39311.1 - 0.077 12.6 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3067 PF11267.3 EKE39311.1 - 0.094 12.8 0.0 0.21 11.6 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3067) DBI_PRT PF02277.12 EKE39311.1 - 0.1 11.6 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyltransferase Sigma54_activ_2 PF14532.1 EKE39311.1 - 0.16 11.9 0.0 0.4 10.7 0.0 1.8 2 1 0 2 2 1 0 Sigma-54 interaction domain CLAG PF03805.8 EKE39312.1 - 6.9e-05 20.4 3.1 8.3e-05 20.1 2.2 1.1 1 0 0 1 1 1 1 Cytoadherence-linked asexual protein Plasmod_Pvs28 PF06247.6 EKE39312.1 - 0.029 13.9 5.6 0.079 12.5 3.9 1.7 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 DUF1049 PF06305.6 EKE39312.1 - 0.3 10.5 1.3 1 8.9 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Adaptin_N PF01602.15 EKE39313.1 - 1.7e-58 198.2 14.6 2.5e-58 197.7 10.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EKE39313.1 - 8.5e-10 38.9 1.7 3.1e-09 37.1 1.1 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 EKE39313.1 - 1.5e-05 24.6 0.0 6.6 7.0 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EKE39313.1 - 1.6e-05 25.1 0.0 2.5 8.4 0.0 4.0 3 1 1 4 4 4 2 HEAT repeats Peptidase_C47 PF05543.8 EKE39313.1 - 0.0042 16.5 0.5 5.8 6.2 0.0 3.8 3 0 0 3 3 3 1 Staphopain peptidase C47 Arm PF00514.18 EKE39313.1 - 0.0054 16.5 0.0 14 5.7 0.0 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EKE39313.1 - 0.038 14.4 0.0 9 6.9 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat TPR_1 PF00515.23 EKE39314.1 - 4e-21 73.6 9.2 1.1e-05 24.8 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKE39314.1 - 3.1e-20 70.3 14.0 1.1e-05 24.9 0.0 8.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EKE39314.1 - 3.7e-18 64.9 14.7 3.6e-09 36.1 0.6 6.5 5 3 2 7 7 7 3 TPR repeat TPR_19 PF14559.1 EKE39314.1 - 2e-13 50.4 5.2 0.0045 17.3 0.1 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EKE39314.1 - 6.7e-13 48.9 0.0 0.00052 20.6 0.0 6.1 6 1 2 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EKE39314.1 - 4.1e-12 46.0 19.4 0.0031 17.5 1.8 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EKE39314.1 - 3.4e-11 42.0 3.8 0.0055 16.4 0.0 6.5 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EKE39314.1 - 2.8e-10 39.8 0.0 0.045 14.3 0.0 5.1 4 1 2 6 6 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE39314.1 - 9.6e-10 38.2 10.5 0.0027 17.6 0.0 6.8 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKE39314.1 - 1.8e-09 36.6 1.1 0.0047 16.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKE39314.1 - 2.7e-08 33.7 1.4 0.27 11.7 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKE39314.1 - 0.00013 21.8 6.5 8.8 6.8 0.0 6.7 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EKE39314.1 - 0.0012 18.6 0.5 2.3 8.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKE39314.1 - 0.0029 17.5 3.2 0.99 9.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat FAT PF02259.18 EKE39314.1 - 0.01 14.8 0.5 1.6 7.6 0.0 3.1 2 1 1 3 3 3 0 FAT domain DUF2225 PF09986.4 EKE39314.1 - 0.015 14.7 3.6 0.35 10.3 0.0 3.5 2 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) MASE1 PF05231.9 EKE39314.1 - 0.061 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 MASE1 Fis1_TPR_C PF14853.1 EKE39314.1 - 0.29 11.0 4.5 48 3.9 0.0 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Yip1 PF04893.12 EKE39315.1 - 0.016 14.7 19.1 0.025 14.0 13.3 1.4 1 1 0 1 1 1 0 Yip1 domain Swi3 PF07962.7 EKE39316.1 - 9.4e-11 41.2 0.0 1.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 GshA PF08886.6 EKE39316.1 - 0.14 10.4 0.6 0.3 9.3 0.0 1.6 1 1 1 2 2 2 0 Glutamate-cysteine ligase Ras PF00071.17 EKE39317.1 - 1.2e-11 44.2 7.2 4.7e-05 22.8 0.5 3.7 4 0 0 4 4 4 3 Ras family Miro PF08477.8 EKE39317.1 - 3.2e-11 43.7 6.6 2e-08 34.7 0.7 3.6 3 1 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 EKE39317.1 - 3.8e-06 26.8 6.0 5.9e-06 26.2 0.5 3.1 4 0 0 4 4 4 1 50S ribosome-binding GTPase Arf PF00025.16 EKE39317.1 - 6.2e-06 25.5 3.3 0.0062 15.7 0.1 4.0 4 0 0 4 4 4 2 ADP-ribosylation factor family PH PF00169.24 EKE39317.1 - 1.9e-05 24.7 0.1 5.6e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 PH domain PduV-EutP PF10662.4 EKE39317.1 - 0.00033 20.1 0.1 0.0015 18.0 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE39317.1 - 0.0012 18.0 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EKE39317.1 - 0.017 14.5 2.1 0.92 8.9 0.1 3.3 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 EKE39318.1 - 4.8e-15 54.7 4.2 2.4e-05 24.0 0.0 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EKE39318.1 - 3e-09 36.6 0.0 8.8e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EKE39318.1 - 0.0013 18.5 1.3 0.0013 18.5 0.9 2.5 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ERCC4 PF02732.10 EKE39319.1 - 3.7e-16 59.1 3.1 6.5e-16 58.3 0.2 2.7 2 0 0 2 2 2 1 ERCC4 domain TPK_catalytic PF04263.11 EKE39321.1 - 4.4e-27 94.1 0.1 5.9e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EKE39321.1 - 1.1e-12 47.5 0.1 1.9e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Pkinase PF00069.20 EKE39322.1 - 6.6e-67 225.3 0.0 8.7e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39322.1 - 3.6e-46 157.3 0.0 5.2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EKE39322.1 - 7.1e-09 35.9 0.0 2.8e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 EKE39322.1 - 2.2e-08 34.2 0.2 5.9e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 EKE39322.1 - 5.1e-05 22.3 0.0 8.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE39322.1 - 0.082 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3738 PF12543.3 EKE39323.1 - 0.0072 15.9 0.2 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3738) Ank PF00023.25 EKE39324.1 - 4.7e-14 51.3 2.7 0.00028 20.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EKE39324.1 - 3.4e-13 49.7 5.3 5.8e-07 29.7 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKE39324.1 - 4.7e-10 38.7 3.8 0.044 14.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EKE39324.1 - 2.9e-08 33.9 1.4 0.98 10.0 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE39324.1 - 6.3e-07 29.4 0.4 0.047 13.9 0.1 3.8 3 1 0 3 3 3 3 Ankyrin repeats (many copies) RasGEF PF00617.14 EKE39325.1 - 8.6e-47 159.3 2.2 1.6e-46 158.4 1.5 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE39325.1 - 5.7e-13 48.8 1.5 3.6e-12 46.2 0.0 2.9 2 1 1 3 3 3 1 RasGEF N-terminal motif zf-C3HC4_3 PF13920.1 EKE39325.1 - 0.14 11.8 11.1 1 9.0 7.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EKE39325.1 - 0.26 10.8 6.0 0.57 9.7 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EKE39325.1 - 0.31 10.9 10.4 0.6 9.9 7.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EKE39325.1 - 0.95 9.2 9.7 2.8 7.7 6.7 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE39325.1 - 1.4 9.0 11.8 3.1 7.8 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SMC_Nse1 PF07574.8 EKE39326.1 - 0.031 13.8 2.3 0.037 13.6 1.6 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex DUF3573 PF12097.3 EKE39326.1 - 0.053 12.1 3.5 0.058 11.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Atg14 PF10186.4 EKE39326.1 - 0.11 11.4 4.0 0.13 11.1 2.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mod_r PF07200.8 EKE39326.1 - 0.33 10.8 5.7 0.37 10.6 3.0 1.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SecA_DEAD PF07517.9 EKE39326.1 - 0.5 9.6 2.9 0.59 9.3 2.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain Pinin_SDK_memA PF04696.8 EKE39326.1 - 0.66 9.5 6.2 0.88 9.1 4.3 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Imm15 PF15590.1 EKE39326.1 - 1.4 8.0 4.8 0.46 9.5 0.5 2.0 1 1 1 2 2 2 0 Immunity protein 15 SRP_SPB PF02978.14 EKE39327.1 - 0.0016 18.6 2.7 0.0018 18.4 1.5 1.5 1 1 0 1 1 1 1 Signal peptide binding domain Cob_adeno_trans PF01923.13 EKE39327.1 - 0.01 15.6 0.4 0.012 15.4 0.3 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF2120 PF09893.4 EKE39327.1 - 0.2 11.5 5.0 0.28 11.1 3.4 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF724 PF05266.9 EKE39327.1 - 0.53 9.8 6.9 0.63 9.6 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_2 PF12848.2 EKE39327.1 - 2.8 7.8 9.5 1.3 8.8 5.2 1.5 1 1 0 1 1 1 0 ABC transporter Ku PF02735.11 EKE39328.1 - 1.2e-06 28.0 0.1 2.4e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain PA26 PF04636.8 EKE39329.1 - 0.036 12.7 5.4 0.042 12.5 3.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SPATIAL PF15256.1 EKE39329.1 - 0.055 13.5 5.4 0.066 13.2 3.8 1.1 1 0 0 1 1 1 0 SPATIAL AAA_23 PF13476.1 EKE39329.1 - 0.16 12.2 9.6 0.2 11.9 6.6 1.1 1 0 0 1 1 1 0 AAA domain U1snRNP70_N PF12220.3 EKE39329.1 - 0.35 11.2 15.3 1 9.7 10.0 2.0 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pox_Ag35 PF03286.9 EKE39329.1 - 0.95 8.9 13.3 1.1 8.7 9.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4407 PF14362.1 EKE39329.1 - 1.1 8.1 5.2 1.5 7.7 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NDUF_B5 PF09781.4 EKE39329.1 - 1.9 7.7 10.6 2.6 7.2 7.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit V_ATPase_I PF01496.14 EKE39329.1 - 5.9 4.6 7.1 6.8 4.4 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3987 PF13148.1 EKE39329.1 - 9.4 4.6 10.4 12 4.2 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3244 PF11589.3 EKE39330.1 - 0.28 10.9 3.7 1.4 8.6 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3244) DUF2838 PF10998.3 EKE39331.1 - 5.5e-29 100.2 8.7 5.5e-29 100.2 6.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DUF2648 PF10855.3 EKE39331.1 - 3.7 7.0 5.9 22 4.6 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2648) dCMP_cyt_deam_1 PF00383.17 EKE39332.1 - 0.003 17.1 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RyR PF02026.11 EKE39334.1 - 0.06 13.3 1.1 0.13 12.3 0.4 1.7 1 1 1 2 2 2 0 RyR domain Arc_PepC PF06819.6 EKE39335.1 - 0.0068 16.3 1.1 0.034 14.0 0.7 2.2 1 0 0 1 1 1 1 Archaeal Peptidase A24 C-terminal Domain TIG PF01833.19 EKE39336.1 - 0.0011 18.8 0.5 0.0026 17.7 0.3 1.6 1 0 0 1 1 1 1 IPT/TIG domain Chromo PF00385.19 EKE39337.1 - 1.7e-09 37.1 3.4 1.6e-06 27.6 0.3 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain CM1 PF03026.10 EKE39337.1 - 0.031 13.3 0.0 0.088 11.9 0.0 1.7 2 0 0 2 2 2 0 Influenza C virus M1 protein CH PF00307.26 EKE39338.1 - 1.7e-17 63.3 0.0 3.7e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.17 EKE39338.1 - 2e-11 43.7 7.3 2.5e-11 43.4 3.9 2.0 2 0 0 2 2 2 1 LIM domain CAMSAP_CH PF11971.3 EKE39338.1 - 2.5e-11 43.0 0.0 6.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain zinc_ribbon_2 PF13240.1 EKE39338.1 - 0.00088 18.6 2.7 1.3 8.6 0.0 3.5 3 0 0 3 3 3 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 EKE39338.1 - 0.016 14.4 3.3 0.47 9.7 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EKE39338.1 - 0.02 14.6 5.3 0.19 11.5 2.8 2.6 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EKE39338.1 - 0.051 13.2 7.8 0.29 10.9 1.8 2.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2706 PF10913.3 EKE39338.1 - 0.65 9.6 2.7 6 6.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2706) Ras PF00071.17 EKE39339.1 - 3e-11 42.9 0.8 3.5e-11 42.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39339.1 - 1.6e-08 35.0 0.5 2.8e-08 34.2 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39339.1 - 1.7e-06 27.4 0.1 2e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE39339.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EKE39339.1 - 0.00061 19.6 1.5 0.01 15.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKE39339.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EKE39339.1 - 0.0077 15.3 0.2 0.0091 15.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE39339.1 - 0.012 15.7 0.2 0.12 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKE39339.1 - 0.025 14.8 0.3 0.049 13.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKE39339.1 - 0.038 13.6 0.5 0.077 12.6 0.4 1.8 1 1 0 1 1 1 0 Archaeal ATPase Peptidase_C3 PF00548.15 EKE39339.1 - 0.054 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) AAA_28 PF13521.1 EKE39339.1 - 0.062 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nit_Regul_Hom PF10126.4 EKE39339.1 - 0.066 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII AAA PF00004.24 EKE39339.1 - 0.12 12.5 0.1 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HUN PF08729.5 EKE39340.1 - 2.7e-07 30.3 0.0 1.5e-06 27.9 0.0 2.3 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Spt5_N PF11942.3 EKE39340.1 - 0.058 14.0 20.9 0.092 13.3 6.7 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 EKE39340.1 - 0.066 11.2 10.3 0.098 10.6 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein KH_1 PF00013.24 EKE39342.1 - 1.5e-09 37.3 0.0 3.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EKE39342.1 - 8.8e-07 28.4 0.7 2.1e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 EKE39342.1 - 0.074 12.6 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 KH domain Rad1 PF02144.11 EKE39343.1 - 1.2e-11 43.9 5.2 5.2e-10 38.5 3.6 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 HAD_2 PF13419.1 EKE39344.1 - 3.7e-20 72.8 0.1 4.4e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE39344.1 - 6.4e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EKE39344.1 - 0.0024 18.3 0.0 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_hydro_26 PF02156.10 EKE39344.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 HAD PF12710.2 EKE39344.1 - 0.02 15.0 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Vps35 PF03635.12 EKE39345.1 - 4.8e-11 41.5 20.6 0.00022 19.5 1.2 3.6 2 1 1 3 3 3 3 Vacuolar protein sorting-associated protein 35 Acetyltransf_9 PF13527.1 EKE39345.1 - 0.026 14.3 0.0 0.088 12.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain LRR_5 PF13306.1 EKE39346.1 - 8.5e-48 161.3 23.2 4.2e-27 94.3 7.4 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE39346.1 - 1.4e-22 79.2 22.4 6.8e-08 32.1 0.1 4.1 1 1 4 5 5 5 5 Leucine rich repeat DEAD PF00270.24 EKE39347.1 - 1.8e-33 115.3 0.2 6.8e-33 113.5 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE39347.1 - 2.3e-26 91.4 0.0 4.7e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE39347.1 - 5.3e-09 36.1 0.0 9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EKE39347.1 - 2.8e-06 26.5 0.0 5.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Pyridoxal_deC PF00282.14 EKE39348.1 - 1.4e-19 69.7 0.0 2.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EKE39348.1 - 1e-12 47.5 0.0 4.6e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EKE39348.1 - 6.6e-05 21.3 0.0 0.00011 20.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SLA_LP_auto_ag PF05889.8 EKE39348.1 - 0.049 12.0 2.7 0.047 12.1 0.2 2.1 3 0 0 3 3 3 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 EKE39348.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase VHS PF00790.14 EKE39349.1 - 0.00028 20.5 2.0 0.00055 19.5 0.1 2.4 1 1 2 3 3 3 1 VHS domain AMPKBI PF04739.10 EKE39349.1 - 0.04 13.7 3.5 1.4 8.8 2.4 2.5 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain KMP11 PF03037.11 EKE39349.1 - 0.52 10.9 3.1 1.4 9.5 0.7 2.6 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 TetR_C_8 PF14278.1 EKE39349.1 - 0.63 10.4 6.9 5.4 7.4 0.0 3.7 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region Rtt106 PF08512.7 EKE39350.1 - 0.033 14.1 0.6 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 Histone chaperone Rttp106-like RasGAP PF00616.14 EKE39350.1 - 0.065 12.8 4.2 0.037 13.6 1.0 1.9 1 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Nup88 PF10168.4 EKE39350.1 - 0.79 7.4 5.3 0.064 11.1 0.4 1.5 2 0 0 2 2 2 0 Nuclear pore component TLD PF07534.11 EKE39352.1 - 1.6e-07 31.4 1.1 3.5e-07 30.2 0.8 1.8 1 1 0 1 1 1 1 TLD Fusion_gly PF00523.13 EKE39352.1 - 0.027 12.5 0.2 0.044 11.8 0.1 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 Hemocyanin_N PF03722.9 EKE39352.1 - 0.86 9.7 5.2 1 9.5 3.0 1.6 1 1 0 1 1 1 0 Hemocyanin, all-alpha domain TFIIB PF00382.14 EKE39353.1 - 0.00016 21.4 0.3 0.81 9.5 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EKE39353.1 - 0.00029 20.0 0.4 0.00029 20.0 0.3 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding DSHCT PF08148.7 EKE39353.1 - 0.045 12.9 0.9 0.078 12.2 0.2 1.7 2 0 0 2 2 2 0 DSHCT (NUC185) domain zf-C2H2_jaz PF12171.3 EKE39353.1 - 0.55 10.4 4.4 1.7 8.9 1.9 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 EKE39353.1 - 0.91 9.0 6.1 0.42 10.0 0.6 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PAP2 PF01569.16 EKE39354.1 - 1.7e-21 76.2 5.4 1.7e-21 76.2 3.7 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF4203 PF13886.1 EKE39354.1 - 0.067 12.6 13.4 0.52 9.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4203) DUF2919 PF11143.3 EKE39354.1 - 0.08 12.7 2.4 0.36 10.6 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) PrgI PF12666.2 EKE39354.1 - 0.1 12.7 6.3 0.96 9.6 0.3 2.8 2 1 1 3 3 3 0 PrgI family protein PsbY PF06298.6 EKE39354.1 - 0.14 11.7 1.2 0.42 10.1 0.9 1.8 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) HSF_DNA-bind PF00447.12 EKE39356.1 - 2.5e-28 98.2 0.4 2.5e-28 98.2 0.3 2.2 2 1 0 2 2 2 1 HSF-type DNA-binding BRAP2 PF07576.7 EKE39356.1 - 0.001 18.5 1.7 1.1 8.8 0.4 2.4 2 0 0 2 2 2 2 BRCA1-associated protein 2 IncA PF04156.9 EKE39356.1 - 7.7 6.0 8.7 0.37 10.3 0.6 2.0 2 0 0 2 2 2 0 IncA protein Smg4_UPF3 PF03467.10 EKE39357.1 - 3.2e-06 27.2 0.4 4.1e-06 26.9 0.3 1.3 1 1 0 1 1 1 1 Smg-4/UPF3 family Ras PF00071.17 EKE39358.1 - 3.8e-52 175.9 0.2 4.6e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39358.1 - 4.6e-15 56.1 1.2 5.7e-15 55.8 0.1 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39358.1 - 3.9e-09 35.9 0.1 5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39358.1 - 1.5e-08 34.3 0.1 5.9e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39358.1 - 0.0024 17.8 1.2 0.0062 16.4 0.1 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE39358.1 - 0.0039 16.4 0.3 0.038 13.2 0.2 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3897 PF13036.1 EKE39358.1 - 0.088 12.4 3.4 0.17 11.4 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) IBR PF01485.16 EKE39359.1 - 4.3e-10 39.2 30.5 4.4e-07 29.6 9.3 4.3 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EKE39359.1 - 0.00035 20.3 8.4 0.00035 20.3 5.8 4.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE39359.1 - 0.0027 17.6 10.9 0.0027 17.6 7.6 5.0 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE39359.1 - 0.0088 15.7 10.0 0.0088 15.7 6.9 4.2 2 2 1 3 3 3 1 zinc-RING finger domain Rap_GAP PF02145.10 EKE39360.1 - 1.3e-53 181.1 0.0 2.2e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP DSPc PF00782.15 EKE39361.1 - 9.5e-23 80.2 0.2 9.5e-23 80.2 0.2 2.4 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EKE39361.1 - 5e-09 36.3 2.9 5e-09 36.3 2.0 2.1 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EKE39361.1 - 0.0052 17.0 0.1 0.028 14.6 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family OmpH PF03938.9 EKE39361.1 - 6.4 6.6 16.7 0.64 9.9 6.6 2.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) PRK PF00485.13 EKE39363.1 - 2.5e-44 151.1 0.0 3.2e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EKE39363.1 - 4.6e-08 33.4 0.0 1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE39363.1 - 6.4e-05 23.7 0.0 0.00015 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKE39363.1 - 0.00032 20.6 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 EKE39363.1 - 0.013 14.9 0.0 0.069 12.5 0.0 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.7 EKE39363.1 - 0.016 14.3 0.0 0.056 12.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 EKE39363.1 - 0.053 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EKE39363.1 - 0.071 13.0 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 EKE39364.1 - 3.3e-29 100.3 0.6 1.6e-14 53.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39364.1 - 4.6e-21 74.4 0.2 8.8e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39364.1 - 2.3e-17 62.7 0.1 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE39364.1 - 0.00065 19.4 0.1 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DAN PF03045.10 EKE39364.1 - 0.0021 17.4 0.5 0.2 11.0 0.0 2.4 1 1 1 2 2 2 2 DAN domain RRM_3 PF08777.6 EKE39364.1 - 0.0022 17.8 0.4 0.057 13.2 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif TPR_MLP1_2 PF07926.7 EKE39365.1 - 0.0031 17.2 8.7 0.0031 17.2 6.0 5.1 1 1 3 4 4 4 1 TPR/MLP1/MLP2-like protein DUF2829 PF11195.3 EKE39365.1 - 1.7 9.2 11.4 1.8 9.1 5.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2829) NAP PF00956.13 EKE39366.1 - 2.9e-15 56.0 7.8 4.1e-15 55.5 5.4 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Mt_ATP-synt_D PF05873.7 EKE39366.1 - 0.061 12.9 2.2 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1409 PF07197.7 EKE39366.1 - 3.3 7.8 5.4 39 4.4 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1409) TLD PF07534.11 EKE39367.1 - 2.5e-08 33.9 2.4 4.2e-08 33.2 1.7 1.4 1 0 0 1 1 1 1 TLD CCDC-167 PF15188.1 EKE39369.1 - 0.0022 17.9 3.4 0.0022 17.9 2.4 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 167 DUF4179 PF13786.1 EKE39369.1 - 0.0023 18.1 0.4 0.0032 17.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) M PF02370.11 EKE39369.1 - 1.1 9.8 5.9 21 5.8 0.2 2.6 2 0 0 2 2 2 0 M protein repeat PTPA PF03095.10 EKE39370.1 - 1e-104 349.9 0.1 1.3e-104 349.6 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Plus-3 PF03126.13 EKE39371.1 - 0.00016 21.6 0.3 0.00016 21.6 0.2 3.2 3 1 1 4 4 4 2 Plus-3 domain Aa_trans PF01490.13 EKE39372.1 - 4.1e-18 65.0 30.5 9.4e-18 63.8 21.1 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein IncA PF04156.9 EKE39372.1 - 4.9 6.7 6.1 3.1 7.3 0.4 2.8 2 0 0 2 2 2 0 IncA protein LRR_5 PF13306.1 EKE39374.1 - 6.5e-65 216.6 54.2 2.7e-30 104.7 10.1 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE39374.1 - 1.6e-21 75.8 25.9 7e-08 32.1 1.1 6.5 1 1 5 6 6 6 6 Leucine rich repeat zf-Tim10_DDP PF02953.10 EKE39374.1 - 0.99 8.7 13.5 1.5 8.1 0.6 3.8 2 1 1 3 3 3 0 Tim10/DDP family zinc finger Ras PF00071.17 EKE39375.1 - 2.1e-52 176.7 0.8 2.5e-52 176.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE39375.1 - 5.2e-21 74.6 0.1 7.3e-21 74.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE39375.1 - 1.5e-17 64.1 0.2 2.3e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE39375.1 - 1e-08 34.8 0.1 6.9e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE39375.1 - 6e-06 25.5 0.1 7.8e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE39375.1 - 3.9e-05 23.5 0.1 6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE39375.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EKE39375.1 - 0.005 16.1 0.0 0.036 13.3 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EKE39375.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKE39375.1 - 0.033 14.1 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EKE39375.1 - 0.041 14.0 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_tran_WbsX PF14307.1 EKE39375.1 - 0.042 13.0 0.2 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX PduV-EutP PF10662.4 EKE39375.1 - 0.05 13.0 0.1 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S11 PF00411.14 EKE39375.1 - 0.11 12.6 0.4 8 6.6 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S11 RhoGAP PF00620.22 EKE39376.1 - 3.1e-21 75.5 0.0 1.2e-20 73.6 0.0 2.1 1 0 0 1 1 1 1 RhoGAP domain LON PF02190.11 EKE39376.1 - 0.21 11.2 7.3 0.12 12.0 1.0 2.7 2 1 0 2 2 2 0 ATP-dependent protease La (LON) domain adh_short PF00106.20 EKE39377.1 - 4.1e-21 75.5 0.0 5.7e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKE39377.1 - 4.5e-07 29.8 0.0 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EKE39377.1 - 0.0018 17.3 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EKE39377.1 - 0.0027 17.1 0.1 0.0053 16.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKE39377.1 - 0.0052 16.4 0.0 0.008 15.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EKE39377.1 - 0.0065 15.3 0.0 0.0093 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EKE39377.1 - 0.018 14.7 0.1 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKE39377.1 - 0.093 13.1 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aa_trans PF01490.13 EKE39379.1 - 1.9e-15 56.2 43.1 9e-15 54.0 29.8 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SPAN PF02510.9 EKE39380.1 - 0.041 12.9 0.5 0.39 9.7 0.0 2.0 1 1 1 2 2 2 0 Surface presentation of antigens protein DUF4163 PF13739.1 EKE39380.1 - 3.7 8.3 6.1 0.92 10.3 1.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4163) DEAD PF00270.24 EKE39381.1 - 3.4e-43 147.0 0.5 3.4e-43 147.0 0.4 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE39381.1 - 2.1e-21 75.5 0.1 1.4e-20 72.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EKE39381.1 - 2.9e-19 68.3 0.0 6.2e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EKE39381.1 - 2e-06 27.7 0.1 2e-06 27.7 0.1 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SMC_N PF02463.14 EKE39381.1 - 0.042 13.0 0.0 1.8 7.7 0.1 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain IBR PF01485.16 EKE39382.1 - 3e-10 39.7 51.4 0.00021 21.1 9.1 5.5 2 1 2 4 4 4 3 IBR domain zf-RING_5 PF14634.1 EKE39382.1 - 6.4e-08 32.2 5.0 6.4e-08 32.2 3.5 6.5 3 2 2 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE39382.1 - 6.7e-05 22.8 5.7 6.7e-05 22.8 3.9 6.3 5 1 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE39382.1 - 9.8e-05 21.9 1.4 9.8e-05 21.9 1.0 6.0 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE39382.1 - 0.00028 20.6 10.6 0.00028 20.6 7.4 5.3 2 1 2 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.1 EKE39382.1 - 0.0079 15.8 1.1 0.0079 15.8 0.8 4.1 2 1 1 3 3 3 1 RING-type zinc-finger RWD PF05773.17 EKE39382.1 - 0.017 15.0 1.3 0.05 13.4 0.9 1.8 1 0 0 1 1 1 0 RWD domain V-SNARE_C PF12352.3 EKE39385.1 - 3.2e-09 36.7 3.6 1e-08 35.0 2.4 1.8 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EKE39385.1 - 5.1e-07 29.2 0.7 7.5e-07 28.7 0.5 1.3 1 0 0 1 1 1 1 Sec20 DUF607 PF04678.8 EKE39385.1 - 0.001 19.0 0.0 0.0011 18.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF607 GAS PF13851.1 EKE39385.1 - 0.0047 16.1 2.3 0.0059 15.8 1.6 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Anoctamin PF04547.7 EKE39385.1 - 0.0098 14.5 0.0 0.011 14.4 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel MFS_2 PF13347.1 EKE39385.1 - 0.015 13.7 0.0 0.017 13.5 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF904 PF06005.7 EKE39385.1 - 0.021 15.0 0.6 0.032 14.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 EKE39385.1 - 0.022 14.4 2.4 0.025 14.2 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SseC PF04888.7 EKE39385.1 - 0.043 13.1 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CemA PF03040.9 EKE39385.1 - 0.058 12.9 0.4 0.067 12.7 0.3 1.0 1 0 0 1 1 1 0 CemA family OATP PF03137.15 EKE39385.1 - 0.073 11.1 0.1 0.074 11.0 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ATG27 PF09451.5 EKE39385.1 - 0.079 12.1 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 FliD_N PF02465.13 EKE39385.1 - 0.13 12.6 0.9 0.19 12.1 0.6 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus BLOC1_2 PF10046.4 EKE39385.1 - 0.15 12.2 2.1 0.2 11.8 1.4 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NEP PF10167.4 EKE39385.1 - 0.18 11.5 2.3 0.36 10.5 1.6 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein Prefoldin_2 PF01920.15 EKE39385.1 - 0.19 11.5 2.5 0.22 11.2 1.4 1.4 1 1 0 1 1 1 0 Prefoldin subunit Fusion_gly PF00523.13 EKE39385.1 - 0.27 9.2 2.2 0.97 7.4 0.3 1.9 1 1 0 2 2 2 0 Fusion glycoprotein F0 DUF3671 PF12420.3 EKE39385.1 - 0.36 10.8 4.0 0.8 9.7 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function ASFV_J13L PF05568.6 EKE39385.1 - 0.48 9.9 6.4 4.8 6.6 2.4 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF912 PF06024.7 EKE39385.1 - 0.67 10.0 3.0 0.84 9.7 2.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Synaptobrevin PF00957.16 EKE39385.1 - 2.4 7.8 7.1 4.2 7.0 4.9 1.6 1 1 0 1 1 1 0 Synaptobrevin Bunya_G2 PF03563.8 EKE39385.1 - 2.5 6.9 5.1 0.89 8.3 1.0 1.8 2 0 0 2 2 2 0 Bunyavirus glycoprotein G2 V_ATPase_I PF01496.14 EKE39385.1 - 3 5.5 5.7 0.35 8.6 1.0 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 EKE39386.1 - 2.1e-35 122.0 62.1 4.5e-30 104.5 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKE39386.1 - 5.5e-15 54.8 25.1 1.4e-13 50.2 16.3 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter DUF4097 PF13349.1 EKE39386.1 - 0.051 13.1 0.3 0.051 13.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Zip PF02535.17 EKE39387.1 - 1.7e-34 119.2 20.8 5.6e-34 117.5 14.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DDDD PF10161.4 EKE39387.1 - 0.056 13.0 1.4 0.41 10.2 0.1 2.5 2 0 0 2 2 2 0 Putative mitochondrial precursor protein DUF1980 PF09323.5 EKE39387.1 - 0.11 12.2 1.0 3.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FA_desaturase PF00487.19 EKE39387.1 - 1.2 8.5 12.0 0.13 11.6 3.1 2.3 1 1 1 2 2 2 0 Fatty acid desaturase Dynamin_M PF01031.15 EKE39388.1 - 6.9e-86 287.6 6.1 6.9e-86 287.6 4.3 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EKE39388.1 - 3.5e-52 176.6 0.2 3.5e-52 176.6 0.1 2.2 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 EKE39388.1 - 2.4e-30 104.2 3.8 6.6e-30 102.8 2.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EKE39388.1 - 2.1e-05 24.4 0.5 0.00018 21.4 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EKE39388.1 - 0.0094 15.0 1.6 0.66 9.0 0.0 2.9 3 0 0 3 3 3 1 AIG1 family FeoB_N PF02421.13 EKE39388.1 - 0.0095 15.2 1.1 0.53 9.5 0.2 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B Miro PF08477.8 EKE39388.1 - 0.037 14.5 0.4 0.037 14.5 0.3 2.7 3 1 0 3 3 3 0 Miro-like protein FAA_hydrolase_N PF09298.6 EKE39388.1 - 0.15 12.0 0.6 20 5.2 0.0 3.2 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal Myosin_head PF00063.16 EKE39390.1 - 2.3e-243 809.2 0.1 2.8e-243 808.9 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EKE39390.1 - 2.6e-57 193.3 1.3 4.7e-57 192.5 0.9 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EKE39390.1 - 1.9e-18 65.6 0.7 4.6e-18 64.3 0.5 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKE39390.1 - 2.1e-17 62.4 0.2 5.8e-17 61.0 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE39390.1 - 8.4e-15 54.0 0.2 3.7e-14 51.9 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EKE39390.1 - 0.00032 20.8 1.2 0.00071 19.7 0.9 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain DUF2075 PF09848.4 EKE39390.1 - 0.00075 18.5 0.1 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EKE39390.1 - 0.004 17.2 0.0 0.017 15.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EKE39390.1 - 0.014 14.8 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EKE39390.1 - 0.023 14.8 1.3 0.16 12.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EKE39390.1 - 0.026 14.1 0.0 0.075 12.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EKE39390.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EKE39390.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain IQ PF00612.22 EKE39390.1 - 0.079 12.6 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_17 PF13207.1 EKE39390.1 - 0.089 13.6 1.0 0.8 10.5 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA_10 PF12846.2 EKE39390.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EKE39390.1 - 0.22 10.3 0.0 0.45 9.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein His_Phos_2 PF00328.17 EKE39391.1 - 4.2e-33 115.1 0.1 5.3e-33 114.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EKE39391.1 - 0.0082 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RhoGEF PF00621.15 EKE39392.1 - 2.1e-38 131.9 5.9 4.2e-38 131.0 4.1 1.5 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EKE39392.1 - 8.9e-17 60.7 10.0 1.9e-16 59.6 7.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE39392.1 - 1.4e-15 57.3 0.8 4.6e-15 55.6 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EKE39392.1 - 0.00041 20.5 0.0 0.011 15.9 0.0 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain zf-DHHC PF01529.15 EKE39392.1 - 0.0062 15.9 0.2 0.0062 15.9 0.1 2.2 3 0 0 3 3 3 1 DHHC palmitoyltransferase PH_8 PF15409.1 EKE39392.1 - 0.028 14.5 0.1 0.093 12.8 0.1 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_5 PF12695.2 EKE39393.1 - 4.8e-17 62.0 0.0 1.6e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE39393.1 - 8.9e-16 58.4 0.0 4.9e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKE39393.1 - 5.7e-10 38.9 0.0 8.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EKE39393.1 - 2e-07 30.8 0.1 3.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 EKE39393.1 - 8e-05 22.9 0.0 0.00011 22.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 EKE39393.1 - 0.001 18.3 0.0 1 8.5 0.0 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EKE39393.1 - 0.0011 18.5 1.3 0.021 14.3 0.0 2.6 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.13 EKE39393.1 - 0.0018 17.6 0.0 0.29 10.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.8 EKE39393.1 - 0.0076 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EKE39393.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Acyl_transf_2 PF02273.10 EKE39393.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase DUF676 PF05057.9 EKE39393.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PfkB PF00294.19 EKE39394.1 - 2.7e-29 102.2 0.0 3.5e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EKE39394.1 - 0.0067 15.7 0.0 0.013 14.7 0.0 1.5 1 1 1 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EKE39394.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase YhdB PF14148.1 EKE39395.1 - 0.00071 19.2 2.4 0.0019 17.9 1.7 1.8 1 1 0 1 1 1 1 YhdB-like protein DUF2959 PF11172.3 EKE39395.1 - 0.032 13.9 3.0 0.037 13.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) THOC7 PF05615.8 EKE39395.1 - 0.045 14.0 10.4 0.092 13.0 7.2 1.5 1 1 1 2 2 2 0 Tho complex subunit 7 FlgN PF05130.7 EKE39395.1 - 0.051 13.8 4.9 0.054 13.7 3.4 1.1 1 0 0 1 1 1 0 FlgN protein IncA PF04156.9 EKE39395.1 - 0.13 11.8 7.3 0.16 11.5 5.1 1.1 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EKE39395.1 - 0.29 8.9 4.5 0.32 8.7 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EKE39395.1 - 0.32 9.3 6.6 0.37 9.1 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2265 PF10023.4 EKE39395.1 - 0.35 9.9 5.7 0.4 9.7 3.9 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) MSG PF02349.10 EKE39395.1 - 0.62 10.0 11.6 0.95 9.4 8.1 1.4 1 1 0 1 1 1 0 Major surface glycoprotein Prefoldin_2 PF01920.15 EKE39395.1 - 0.69 9.7 14.4 2.1 8.1 4.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit Tho2 PF11262.3 EKE39395.1 - 0.8 8.6 7.0 0.94 8.4 4.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Clathrin_lg_ch PF01086.12 EKE39395.1 - 1.2 8.9 9.4 0.52 10.1 1.9 2.1 1 1 1 2 2 2 0 Clathrin light chain Pepsin-I3 PF06394.8 EKE39395.1 - 1.9 8.2 5.6 1.9 8.1 3.2 1.6 1 1 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain AAA_23 PF13476.1 EKE39395.1 - 5.9 7.1 12.1 7.2 6.8 8.4 1.1 1 0 0 1 1 1 0 AAA domain PfkB PF00294.19 EKE39396.1 - 9.4e-56 189.1 0.1 1.1e-55 188.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Fer4_7 PF12838.2 EKE39398.1 - 8.9e-10 38.8 26.1 6.8e-06 26.3 10.0 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.22 EKE39398.1 - 1.4e-09 37.1 16.0 1.8e-07 30.4 3.2 2.3 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EKE39398.1 - 3.4e-08 33.6 12.6 4.8e-08 33.1 8.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE39398.1 - 3.8e-08 32.8 15.0 6.9e-07 28.8 3.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 EKE39398.1 - 4.9e-08 32.6 11.2 6.9e-08 32.1 7.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EKE39398.1 - 1.1e-07 31.5 14.6 1.8e-07 30.9 10.1 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE39398.1 - 5e-07 29.2 15.9 1.2e-05 24.8 2.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EKE39398.1 - 2.4e-06 27.4 24.5 0.00015 21.7 9.1 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EKE39398.1 - 6.9e-06 26.5 11.2 2.5e-05 24.7 7.7 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_16 PF13484.1 EKE39398.1 - 0.00056 20.5 11.7 0.54 11.0 5.2 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 EKE39398.1 - 0.0017 18.5 17.4 0.0056 16.9 2.7 2.4 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_11 PF13247.1 EKE39398.1 - 0.0021 17.9 8.9 0.028 14.3 6.2 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.1 EKE39398.1 - 0.0022 18.3 12.9 0.0092 16.3 9.0 1.9 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_18 PF13746.1 EKE39398.1 - 0.005 17.2 5.1 0.005 17.2 3.5 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EKE39398.1 - 0.0052 17.1 13.3 0.086 13.1 2.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 EKE39398.1 - 0.023 15.2 20.1 0.061 13.9 4.6 2.4 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_20 PF14691.1 EKE39398.1 - 0.78 9.3 11.5 0.44 10.1 1.4 2.1 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_19 PF06902.6 EKE39398.1 - 1 9.2 9.8 1.9 8.3 6.8 1.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Ras PF00071.17 EKE39399.1 - 9.6e-53 177.8 0.0 1.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39399.1 - 6.5e-16 58.9 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39399.1 - 2.7e-05 23.4 0.0 7.5e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39399.1 - 0.0044 16.4 0.3 0.017 14.5 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EKE39399.1 - 0.12 11.9 1.1 4.1 6.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain Glyco_hydro_15 PF00723.16 EKE39400.1 - 1.4e-07 30.4 2.3 0.0065 15.0 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Prenyltrans_2 PF13249.1 EKE39400.1 - 0.04 14.3 0.0 0.17 12.2 0.0 2.0 1 1 0 1 1 1 0 Prenyltransferase-like Pkinase PF00069.20 EKE39402.1 - 5.5e-48 163.3 0.1 9.4e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39402.1 - 1.6e-19 70.0 0.1 4.1e-19 68.6 0.0 1.6 1 1 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 EKE39402.1 - 0.0036 16.9 0.7 0.0066 16.0 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKE39402.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Beach PF02138.13 EKE39403.1 - 1.2e-14 54.4 0.5 2.4e-07 30.5 0.1 2.6 2 0 0 2 2 2 2 Beige/BEACH domain Laminin_G_3 PF13385.1 EKE39403.1 - 5.5e-07 29.9 0.2 1e-06 29.1 0.2 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH PF00169.24 EKE39404.1 - 3.9e-09 36.6 0.2 9e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EKE39404.1 - 0.007 16.6 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SMC_hinge PF06470.8 EKE39404.1 - 0.11 12.4 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain tRNA-synt_2b PF00587.20 EKE39405.1 - 1.7e-47 161.2 0.9 3.3e-47 160.2 0.3 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKE39405.1 - 4.7e-22 77.7 0.7 1.2e-21 76.4 0.5 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EKE39405.1 - 9.2e-09 35.0 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EKE39405.1 - 0.04 13.7 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 TGS domain Lipase3_N PF03893.11 EKE39405.1 - 0.11 12.3 0.2 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Lipase 3 N-terminal region TLD PF07534.11 EKE39408.1 - 0.00024 21.1 0.4 0.0003 20.8 0.2 1.2 1 0 0 1 1 1 1 TLD CH PF00307.26 EKE39409.1 - 8.9e-18 64.3 0.1 3.3e-17 62.4 0.1 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.17 EKE39409.1 - 4.8e-10 39.3 6.1 1.3e-09 38.0 4.2 1.8 1 0 0 1 1 1 1 LIM domain CAMSAP_CH PF11971.3 EKE39409.1 - 2.6e-09 36.5 0.0 9.7e-09 34.7 0.0 2.1 1 0 0 1 1 1 1 CAMSAP CH domain DZR PF12773.2 EKE39409.1 - 1.2 8.9 6.4 6.1 6.7 4.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon Lactamase_B_2 PF12706.2 EKE39411.1 - 9.7e-27 93.7 0.3 1.6e-26 93.1 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EKE39411.1 - 1.6e-10 40.2 0.0 3.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EKE39411.1 - 2.3e-09 37.1 0.1 9.5e-09 35.1 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EKE39411.1 - 0.037 13.7 0.1 0.093 12.4 0.1 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Aha1_N PF09229.6 EKE39412.1 - 5.2e-05 23.0 2.7 5.2e-05 23.0 1.9 2.0 2 1 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal CsgG PF03783.9 EKE39412.1 - 0.077 12.0 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG MIB_HERC2 PF06701.8 EKE39413.1 - 0.034 14.0 0.1 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Mib_herc2 Sec6 PF06046.8 EKE39414.1 - 2.1e-61 207.6 11.5 2.1e-61 207.6 8.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Talin_middle PF09141.5 EKE39414.1 - 0.025 14.2 0.4 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Talin, middle domain CDC45 PF02724.9 EKE39415.1 - 0.22 9.5 14.5 0.36 8.8 10.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S41 PF03572.13 EKE39416.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S41 Ribosomal_L7Ae PF01248.21 EKE39417.1 - 2.1e-22 78.4 0.2 2.5e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MoCo_carrier PF12694.2 EKE39417.1 - 0.047 13.1 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative molybdenum carrier Mob1_phocein PF03637.12 EKE39418.1 - 3.6e-54 183.0 1.9 4.2e-54 182.8 1.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family Cellulase PF00150.13 EKE39419.1 - 0.12 11.5 0.2 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) LRR_7 PF13504.1 EKE39419.1 - 3.3 8.3 21.9 28 5.5 0.4 8.0 7 1 0 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 EKE39419.1 - 6.4 6.5 24.1 3.6 7.3 4.3 6.0 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) HSP70 PF00012.15 EKE39420.1 - 5.6e-83 278.8 2.9 6.8e-83 278.5 2.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE39420.1 - 1.3e-09 37.1 1.5 1.2e-08 33.9 1.1 2.2 1 1 0 1 1 1 1 MreB/Mbl protein Fibrillarin PF01269.12 EKE39420.1 - 0.00095 18.1 0.1 0.035 13.0 0.0 2.3 2 0 0 2 2 2 1 Fibrillarin Hydantoinase_A PF01968.13 EKE39420.1 - 0.055 12.5 0.8 3.2 6.7 0.1 2.3 1 1 0 2 2 2 0 Hydantoinase/oxoprolinase Ras PF00071.17 EKE39422.1 - 1.1e-56 190.6 2.5 1.4e-56 190.3 1.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39422.1 - 6.4e-20 71.8 0.4 6.4e-20 71.8 0.2 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39422.1 - 2.3e-15 56.2 0.5 3.2e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39422.1 - 5.2e-07 29.2 0.3 3e-06 26.8 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EKE39422.1 - 6e-06 25.6 0.4 2.6e-05 23.5 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EKE39422.1 - 1.9e-05 23.9 0.4 3.2e-05 23.2 0.3 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE39422.1 - 2e-05 24.5 0.8 2.9e-05 24.0 0.5 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE39422.1 - 2.8e-05 23.3 1.0 4.3e-05 22.7 0.6 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EKE39422.1 - 0.0014 18.3 0.3 0.0051 16.5 0.0 1.8 1 1 1 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 EKE39422.1 - 0.0015 18.0 0.3 0.027 13.9 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE39422.1 - 0.0031 16.7 0.9 0.015 14.4 0.6 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EKE39422.1 - 0.0082 15.1 0.4 0.017 14.1 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_22 PF13401.1 EKE39422.1 - 0.015 15.4 0.0 0.056 13.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 EKE39422.1 - 0.02 14.5 0.1 0.045 13.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EKE39422.1 - 0.038 13.4 0.0 0.047 13.1 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EKE39422.1 - 0.041 14.0 0.2 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE39422.1 - 0.05 13.5 0.0 0.075 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EKE39422.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AHSA1 PF08327.6 EKE39423.1 - 3.4e-18 65.9 0.0 3.8e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EKE39423.1 - 0.0048 17.0 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Radical_SAM PF04055.16 EKE39424.1 - 5.4e-24 85.2 0.2 7.6e-24 84.7 0.2 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EKE39424.1 - 0.00092 19.3 1.1 0.00092 19.3 0.7 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain DZR PF12773.2 EKE39424.1 - 0.0032 17.2 3.0 0.0032 17.2 2.0 3.1 3 0 0 3 3 3 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EKE39424.1 - 0.0047 16.0 0.4 0.0047 16.0 0.3 3.2 4 0 0 4 4 4 1 zinc-ribbon domain Auto_anti-p27 PF06677.7 EKE39424.1 - 0.012 15.3 2.5 2.6 7.8 0.2 2.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.7 EKE39424.1 - 0.024 13.9 0.1 0.024 13.9 0.1 2.6 3 1 0 3 3 3 0 TFIIB zinc-binding ADK_lid PF05191.9 EKE39424.1 - 0.035 13.7 1.3 0.094 12.3 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.1 EKE39424.1 - 0.061 12.8 0.7 0.061 12.8 0.5 3.3 5 0 0 5 5 5 0 zinc-ribbon domain Fer4_14 PF13394.1 EKE39424.1 - 3.7 7.5 9.8 0.2 11.6 2.1 2.4 2 1 1 3 3 3 0 4Fe-4S single cluster domain RNA_pol_L PF01193.19 EKE39425.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain SUI1 PF01253.17 EKE39426.1 - 2.7e-11 43.1 4.5 4.6e-11 42.3 3.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Tom37_C PF11801.3 EKE39426.1 - 0.084 12.7 1.9 0.096 12.5 1.3 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain GOLD_2 PF13897.1 EKE39426.1 - 0.44 10.7 4.4 0.59 10.3 3.0 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking ATP11 PF06644.6 EKE39426.1 - 0.78 9.1 9.2 1.1 8.7 6.4 1.1 1 0 0 1 1 1 0 ATP11 protein APG12 PF04110.8 EKE39427.1 - 0.00036 20.6 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad60-SLD PF11976.3 EKE39427.1 - 0.013 15.2 0.1 0.03 13.9 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Vps39_2 PF10367.4 EKE39428.1 - 0.0024 18.0 1.9 0.074 13.2 0.4 2.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EKE39428.1 - 0.0035 17.1 7.1 0.0093 15.7 4.9 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 EKE39428.1 - 0.0052 16.4 1.9 0.012 15.3 1.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 TPR_8 PF13181.1 EKE39428.1 - 0.047 13.4 0.2 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EKE39428.1 - 0.085 12.8 5.3 0.25 11.3 3.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Frag1 PF10277.4 EKE39428.1 - 0.12 11.7 0.6 0.28 10.6 0.4 1.5 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family zf-RING_5 PF14634.1 EKE39428.1 - 0.22 11.3 8.3 0.53 10.0 5.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EKE39428.1 - 0.26 10.9 5.8 0.74 9.5 4.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKE39428.1 - 0.49 10.5 6.8 0.2 11.8 2.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger RNA_pol_Rpc34 PF05158.7 EKE39429.1 - 1.7e-10 40.6 1.8 6.8e-09 35.3 0.3 2.1 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit RSS_P20 PF11757.3 EKE39430.1 - 0.013 15.6 1.2 0.034 14.2 0.8 1.7 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like FlxA PF14282.1 EKE39430.1 - 0.04 13.8 8.5 0.18 11.7 1.1 2.4 2 0 0 2 2 2 0 FlxA-like protein Rap_GAP PF02145.10 EKE39431.1 - 1.3e-34 119.2 0.2 2.6e-34 118.2 0.2 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Ank_2 PF12796.2 EKE39431.1 - 3.2e-25 88.2 4.8 4.3e-08 33.3 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE39431.1 - 8.7e-20 69.4 9.4 2e-06 27.3 0.1 5.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EKE39431.1 - 8.8e-19 65.7 8.5 0.00028 20.8 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EKE39431.1 - 5.3e-16 58.2 6.1 1e-07 31.9 0.1 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKE39431.1 - 1e-13 51.3 2.9 3.1e-06 27.5 0.2 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Cwf_Cwc_15 PF04889.7 EKE39431.1 - 0.16 11.6 2.4 0.39 10.4 1.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FliG_N PF14842.1 EKE39432.1 - 0.03 14.4 0.2 0.067 13.3 0.1 1.7 2 0 0 2 2 2 0 FliG N-terminal domain Fer2_3 PF13085.1 EKE39432.1 - 0.053 13.3 0.6 0.077 12.8 0.4 1.4 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain UCH PF00443.24 EKE39435.1 - 6.5e-54 182.8 0.7 4.8e-53 179.9 0.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE39435.1 - 2.8e-26 92.6 0.0 7.4e-23 81.4 0.0 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase dUTPase PF00692.14 EKE39436.1 - 8.5e-43 144.9 0.0 9.4e-43 144.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase SNase PF00565.12 EKE39439.1 - 1e-24 86.8 20.7 4.8e-08 33.2 0.1 5.8 6 0 0 6 6 6 4 Staphylococcal nuclease homologue TUDOR PF00567.19 EKE39439.1 - 1.7e-06 27.8 0.1 1.7e-06 27.8 0.0 3.0 3 0 0 3 3 3 1 Tudor domain MFS_1 PF07690.11 EKE39441.1 - 1.1e-27 96.6 32.3 6.3e-21 74.4 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3278 PF11683.3 EKE39441.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) PUF PF00806.14 EKE39443.1 - 5.7e-60 195.5 11.7 2.9e-08 32.7 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF223 PF02721.9 EKE39443.1 - 0.93 9.6 6.0 0.82 9.7 2.0 2.5 3 1 0 3 3 3 0 Domain of unknown function DUF223 Ras PF00071.17 EKE39444.1 - 2.9e-07 30.0 2.0 1.3e-06 27.9 1.4 2.0 1 1 0 1 1 1 1 Ras family Arf PF00025.16 EKE39444.1 - 0.00022 20.4 0.2 0.00045 19.5 0.2 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE39444.1 - 0.00056 20.3 0.1 0.002 18.5 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Sigma70_r1_1 PF03979.9 EKE39444.1 - 0.062 13.2 3.1 2.3 8.2 0.1 3.2 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 TFIIS_C PF01096.13 EKE39445.1 - 3e-15 55.5 2.1 4.8e-15 54.9 1.5 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.9 EKE39445.1 - 8e-10 38.7 1.5 1.2e-09 38.2 1.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TF_Zn_Ribbon PF08271.7 EKE39445.1 - 0.0011 18.1 0.2 0.0033 16.7 0.2 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EKE39445.1 - 0.026 14.3 0.3 0.056 13.2 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain UPF0193 PF05250.6 EKE39445.1 - 0.034 13.7 0.8 0.06 12.9 0.3 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0193) Elf1 PF05129.8 EKE39445.1 - 0.14 11.9 2.2 0.25 11.0 1.6 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EKE39445.1 - 0.54 9.9 3.0 4.7 6.9 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EKE39445.1 - 2.9 7.4 6.9 0.99 8.9 0.1 2.8 4 0 0 4 4 4 0 zinc-ribbon domain ATP-synt_8 PF00895.15 EKE39446.1 - 0.5 10.6 5.3 1.7 8.9 2.0 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 Abhydrolase_5 PF12695.2 EKE39447.1 - 1.1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE39447.1 - 3.8e-08 33.5 0.0 2.3e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKE39447.1 - 2.2e-05 23.7 0.0 3.8e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EKE39447.1 - 0.00018 21.2 0.0 0.17 11.5 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EKE39447.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EKE39447.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EKE39447.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold FtsX PF02687.16 EKE39448.1 - 3 7.6 10.0 5.5 6.7 0.4 2.6 2 0 0 2 2 2 0 FtsX-like permease family Matrilin_ccoil PF10393.4 EKE39449.1 - 0.0017 17.6 1.2 0.0047 16.2 0.9 1.8 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin DELLA PF12041.3 EKE39449.1 - 0.051 13.2 0.7 0.14 11.7 0.2 1.9 2 1 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Snapin_Pallidin PF14712.1 EKE39449.1 - 0.17 12.1 3.5 0.34 11.2 2.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Tox-ODYAM1 PF15642.1 EKE39449.1 - 0.6 8.7 9.3 0.75 8.4 6.5 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TMPIT PF07851.8 EKE39449.1 - 1.1 8.3 5.6 1.3 7.9 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2013 PF09431.5 EKE39450.1 - 0.001 18.8 5.1 0.0028 17.4 3.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) UNC45-central PF11701.3 EKE39450.1 - 0.13 11.9 3.5 2.7 7.6 0.5 2.3 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central PH PF00169.24 EKE39451.1 - 1.9e-11 44.0 0.4 4.9e-11 42.7 0.2 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EKE39451.1 - 0.0044 17.2 0.4 0.015 15.5 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EKE39451.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.1 EKE39451.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 PH domain Ribosomal_L32e PF01655.13 EKE39452.1 - 2e-43 146.8 0.5 2.5e-43 146.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DUF884 PF05959.6 EKE39452.1 - 0.067 12.4 0.1 0.088 12.1 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Pkinase PF00069.20 EKE39453.1 - 6.8e-68 228.6 0.0 7.9e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39453.1 - 3.1e-34 118.2 0.0 4.1e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39453.1 - 1.5e-06 27.4 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Exo70 PF03081.10 EKE39454.1 - 2.8e-31 108.6 18.9 5.4e-31 107.6 9.8 3.2 2 1 1 3 3 3 2 Exo70 exocyst complex subunit DUF465 PF04325.8 EKE39454.1 - 0.025 14.2 1.3 0.072 12.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) KH_1 PF00013.24 EKE39456.1 - 9.6e-05 21.9 0.9 0.00023 20.7 0.6 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EKE39456.1 - 0.0065 16.0 0.4 0.02 14.5 0.3 1.9 1 0 0 1 1 1 1 KH domain TPR_11 PF13414.1 EKE39457.1 - 1.8e-40 136.3 5.9 1.5e-12 46.9 0.0 4.4 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 EKE39457.1 - 2.3e-33 112.4 4.8 1.1e-05 24.8 0.0 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 EKE39457.1 - 2.5e-32 108.1 1.2 0.00015 21.4 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 EKE39457.1 - 1.4e-27 95.3 7.0 6.7e-08 32.3 0.1 4.8 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKE39457.1 - 1.4e-21 76.5 0.0 3.5e-06 27.5 0.0 4.5 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EKE39457.1 - 3.8e-21 73.2 1.8 0.0069 16.0 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EKE39457.1 - 2.2e-18 64.8 6.7 0.00016 21.6 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EKE39457.1 - 4.6e-18 64.0 0.1 0.19 12.4 0.0 6.5 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 EKE39457.1 - 6.4e-13 48.8 2.2 0.004 17.4 0.0 4.6 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 EKE39457.1 - 2.7e-12 46.3 0.1 0.087 12.6 0.0 5.6 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EKE39457.1 - 4.1e-10 38.6 1.4 6.3 6.8 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EKE39457.1 - 2.3e-09 37.2 2.6 0.00014 21.8 0.1 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKE39457.1 - 2.1e-06 27.8 5.6 0.09 13.2 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EKE39457.1 - 3.2e-06 26.4 0.1 0.0014 17.7 0.0 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKE39457.1 - 0.00051 19.8 3.6 0.19 11.7 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EKE39457.1 - 0.006 16.6 2.8 0.82 9.8 0.0 3.9 3 1 1 5 5 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 EKE39457.1 - 0.029 14.3 0.1 0.32 11.0 0.0 2.4 2 1 2 4 4 3 0 Tetratrico peptide repeat BTAD PF03704.12 EKE39457.1 - 0.03 14.6 0.2 5.4 7.3 0.0 2.8 2 1 2 4 4 3 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 EKE39457.1 - 1.8 9.2 4.3 3.6 8.3 0.0 3.7 6 0 0 6 6 3 0 Tetratricopeptide repeat PEP-utilizers_C PF02896.13 EKE39458.1 - 1.8e-108 361.8 0.1 2.7e-108 361.3 0.1 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 EKE39458.1 - 1.7e-55 188.3 0.0 5e-55 186.8 0.0 1.7 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 EKE39458.1 - 1.1e-19 69.8 0.7 2.5e-19 68.6 0.5 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain WD40 PF00400.27 EKE39460.1 - 1.5e-45 151.5 12.6 3.2e-12 45.8 0.4 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE39460.1 - 4.8e-05 23.1 1.2 0.18 11.5 0.1 2.8 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Lactonase PF10282.4 EKE39460.1 - 0.0033 16.5 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Ribosomal_L37e PF01907.14 EKE39461.1 - 3e-24 84.5 12.0 4.6e-24 83.9 8.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EKE39461.1 - 0.0037 17.0 3.8 0.0052 16.5 2.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C2HC5 PF06221.8 EKE39461.1 - 0.035 13.8 3.3 0.051 13.3 2.3 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF4543 PF15076.1 EKE39461.1 - 0.078 13.0 0.1 0.097 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) zinc_ribbon_6 PF14599.1 EKE39461.1 - 0.13 12.0 4.1 0.21 11.4 2.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon FeS PF04060.8 EKE39461.1 - 0.16 11.5 1.4 2 8.0 0.1 2.3 2 0 0 2 2 2 0 Putative Fe-S cluster HypA PF01155.14 EKE39461.1 - 0.18 11.5 2.2 0.21 11.2 1.5 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EKE39461.1 - 0.24 10.6 1.8 5 6.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 EKE39461.1 - 0.25 11.0 3.3 0.93 9.2 2.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS91 PF14319.1 EKE39461.1 - 0.43 10.1 4.1 0.48 9.9 2.8 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain DNA_RNApol_7kD PF03604.8 EKE39461.1 - 0.73 9.3 7.1 1.4 8.4 0.9 2.3 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC4_3 PF13920.1 EKE39461.1 - 0.83 9.3 4.9 1.2 8.8 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tnp_zf-ribbon_2 PF13842.1 EKE39461.1 - 1.7 9.1 7.5 19 5.7 5.4 2.2 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_2 PF13923.1 EKE39461.1 - 1.9 8.6 6.4 2.7 8.0 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FdhE PF04216.7 EKE39461.1 - 2 8.0 6.2 2.2 7.9 4.3 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation TLD PF07534.11 EKE39462.1 - 6.6e-06 26.1 0.7 6.6e-06 26.1 0.5 2.4 3 0 0 3 3 3 1 TLD GUCT PF08152.7 EKE39462.1 - 0.046 13.6 2.9 0.15 12.0 0.0 3.1 3 1 0 3 3 3 0 GUCT (NUC152) domain Pkinase PF00069.20 EKE39463.1 - 6.1e-65 218.9 0.0 7.6e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39463.1 - 1e-46 159.1 0.0 1.3e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39463.1 - 0.0014 17.6 0.0 0.0028 16.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EKE39463.1 - 0.0098 15.2 0.8 0.02 14.2 0.2 1.7 1 1 0 2 2 2 1 RIO1 family Kdo PF06293.9 EKE39463.1 - 0.13 11.3 0.2 0.23 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop25 PF09805.4 EKE39463.1 - 0.59 10.1 16.4 0.88 9.6 11.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2457 PF10446.4 EKE39463.1 - 0.76 8.4 29.7 1.1 7.9 20.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 EKE39463.1 - 1.1 7.3 11.8 1.5 6.9 8.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sigma70_ner PF04546.8 EKE39463.1 - 1.2 8.7 17.5 2.4 7.7 12.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 EKE39463.1 - 2.9 7.2 13.8 4.5 6.5 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EKE39463.1 - 3 6.7 15.4 5 6.0 10.7 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.3 EKE39463.1 - 5.2 6.9 26.2 8.4 6.2 18.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 EKE39463.1 - 5.5 6.1 21.9 8.6 5.5 15.2 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EKE39463.1 - 8.7 4.2 20.9 12 3.7 14.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 EKE39463.1 - 9.3 6.0 23.1 13 5.5 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.5 EKE39463.1 - 9.8 6.1 11.0 15 5.5 7.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ubiquitin PF00240.18 EKE39464.1 - 1.8e-33 113.7 0.5 2e-33 113.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE39464.1 - 7.1e-21 73.6 0.4 7.9e-21 73.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKE39464.1 - 7.8e-06 26.0 0.1 3.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EKE39464.1 - 0.00028 20.5 0.0 0.00032 20.4 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EKE39464.1 - 0.0047 16.7 0.1 0.0092 15.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EKE39464.1 - 0.013 15.5 0.1 0.036 14.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EKE39464.1 - 0.085 12.7 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG eRF1_1 PF03463.10 EKE39464.1 - 0.11 12.0 0.0 2.4 7.7 0.0 2.0 1 1 1 2 2 2 0 eRF1 domain 1 DUF2407 PF10302.4 EKE39464.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain VHS PF00790.14 EKE39465.1 - 1.2e-07 31.4 0.9 1.2e-07 31.4 0.6 2.4 2 1 0 3 3 3 1 VHS domain PSD2 PF07624.6 EKE39465.1 - 0.021 14.4 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) DUF4355 PF14265.1 EKE39465.1 - 0.12 12.3 1.5 0.3 11.0 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Pkinase PF00069.20 EKE39466.1 - 3.8e-52 177.0 0.9 5.1e-52 176.5 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39466.1 - 6.1e-22 77.9 0.1 8.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Synapsin PF02078.11 EKE39466.1 - 0.05 13.7 0.1 0.34 11.0 0.1 2.2 2 0 0 2 2 2 0 Synapsin, N-terminal domain DivIC PF04977.10 EKE39466.1 - 0.083 12.3 0.4 0.21 11.0 0.1 1.7 2 0 0 2 2 2 0 Septum formation initiator RestrictionMunI PF11407.3 EKE39468.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Type II restriction enzyme MunI zf-RING_5 PF14634.1 EKE39469.1 - 0.015 14.9 15.8 0.035 13.8 10.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE39469.1 - 0.026 14.5 15.8 0.058 13.4 11.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKE39469.1 - 0.036 13.7 6.7 0.019 14.7 2.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EKE39469.1 - 0.074 12.6 5.6 0.24 10.9 3.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 EKE39469.1 - 0.18 11.4 16.3 0.44 10.2 11.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE39469.1 - 0.44 10.4 12.9 0.9 9.4 8.9 1.6 1 0 0 1 1 1 0 Ring finger domain HemX PF04375.9 EKE39470.1 - 0.0094 14.5 5.0 0.013 14.0 3.5 1.3 1 0 0 1 1 1 1 HemX Peptidase_C11 PF03415.9 EKE39470.1 - 0.018 14.0 1.8 0.02 13.8 1.3 1.0 1 0 0 1 1 1 0 Clostripain family Seadorna_VP6 PF07407.6 EKE39470.1 - 0.019 13.7 0.8 0.02 13.6 0.5 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF2207 PF09972.4 EKE39470.1 - 0.02 13.5 1.9 0.022 13.3 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4618 PF15397.1 EKE39470.1 - 0.023 14.0 14.6 0.028 13.7 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Lebercilin PF15619.1 EKE39470.1 - 0.042 13.2 14.5 0.08 12.3 2.9 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NuA4 PF09340.5 EKE39470.1 - 0.051 13.2 5.0 0.087 12.4 3.5 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Aminotran_1_2 PF00155.16 EKE39470.1 - 0.061 12.2 0.1 0.075 11.9 0.1 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II DUF1202 PF06717.6 EKE39470.1 - 0.26 10.5 8.7 0.21 10.8 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1202) Phlebovirus_NSM PF07246.6 EKE39470.1 - 0.33 10.0 12.7 0.21 10.6 1.0 2.0 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M KIAA1328 PF15369.1 EKE39470.1 - 0.7 9.6 15.6 1.1 8.9 10.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein KIAA1328 Atg14 PF10186.4 EKE39470.1 - 0.81 8.5 11.9 1 8.2 8.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EKE39470.1 - 0.9 9.6 12.0 1.6 8.8 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EKE39470.1 - 0.92 9.9 10.1 0.86 10.0 3.6 2.3 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.10 EKE39470.1 - 1.1 9.1 17.0 0.26 11.1 1.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper COQ7 PF03232.8 EKE39470.1 - 1.1 8.6 4.9 0.36 10.2 0.5 1.9 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 TSC22 PF01166.13 EKE39470.1 - 1.2 9.1 16.2 0.37 10.7 4.9 2.9 1 1 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 EKE39470.1 - 1.7 8.2 20.7 1.7 8.2 1.9 3.3 1 1 2 3 3 3 0 Septum formation initiator APG6 PF04111.7 EKE39470.1 - 2.5 7.0 17.0 3.2 6.6 11.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 EKE39470.1 - 5.4 7.0 7.5 4.5 7.3 0.5 2.8 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat AKNA PF12443.3 EKE39470.1 - 7.4 6.6 12.8 0.83 9.7 0.9 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF724 PF05266.9 EKE39470.1 - 8.9 5.8 14.2 3.3 7.2 7.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) zf-C4H2 PF10146.4 EKE39471.1 - 0.018 15.0 2.7 0.021 14.8 1.9 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein HAUS5 PF14817.1 EKE39471.1 - 0.041 12.4 0.9 0.048 12.2 0.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Prefoldin_2 PF01920.15 EKE39471.1 - 0.041 13.6 9.3 0.78 9.5 0.4 2.1 2 0 0 2 2 2 0 Prefoldin subunit zf-C4pol PF14260.1 EKE39471.1 - 0.12 12.3 0.6 1.1 9.2 0.1 2.0 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta HTH_Tnp_Tc5 PF03221.11 EKE39471.1 - 0.16 11.7 0.6 0.26 11.1 0.1 1.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain ACCA PF03255.9 EKE39471.1 - 0.23 11.0 3.3 0.3 10.6 2.3 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Cep57_CLD_2 PF14197.1 EKE39471.1 - 0.43 10.5 2.5 2.4 8.1 1.7 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Nodulin-like PF06813.8 EKE39472.1 - 0.0063 15.7 4.7 0.0063 15.7 3.3 1.8 1 1 1 2 2 2 2 Nodulin-like Got1 PF04178.7 EKE39472.1 - 0.011 15.8 4.5 0.012 15.7 3.1 1.2 1 0 0 1 1 1 0 Got1/Sft2-like family DUF3784 PF12650.2 EKE39472.1 - 0.015 15.2 7.3 0.024 14.5 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) PGG PF13962.1 EKE39472.1 - 0.084 12.4 3.0 0.11 12.0 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF3671 PF12420.3 EKE39472.1 - 1.4 8.9 9.5 1.8 8.5 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2207 PF09972.4 EKE39472.1 - 2.3 6.6 6.1 2.5 6.5 4.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rho_N PF07498.7 EKE39473.1 - 0.47 10.2 9.2 6.1 6.6 0.0 4.2 4 0 0 4 4 4 0 Rho termination factor, N-terminal domain GNAT_acetyltran PF12746.2 EKE39474.1 - 0.035 12.9 3.7 0.044 12.6 1.8 1.6 1 1 0 1 1 1 0 GNAT acetyltransferase GDPD PF03009.12 EKE39475.1 - 8.9e-24 84.3 0.0 3.4e-23 82.4 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1282 PF06930.7 EKE39476.1 - 0.023 14.3 8.7 0.043 13.4 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) SPC25 PF06703.6 EKE39476.1 - 0.1 12.1 0.5 0.22 11.0 0.4 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ninjurin PF04923.7 EKE39476.1 - 1.1 9.0 9.0 7.1 6.4 6.3 2.1 1 1 0 1 1 1 0 Ninjurin Arm PF00514.18 EKE39477.1 - 0.039 13.7 0.2 3.6 7.5 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EKE39477.1 - 0.064 13.0 0.1 0.064 13.0 0.1 2.6 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain bact-PGI_C PF10432.4 EKE39477.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region RhoGEF PF00621.15 EKE39478.1 - 3.3e-40 137.8 8.8 3.3e-40 137.8 6.1 2.8 3 1 0 3 3 3 1 RhoGEF domain FYVE PF01363.16 EKE39478.1 - 4.2e-18 64.9 9.5 1.2e-17 63.5 6.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE39478.1 - 8.6e-09 35.5 1.3 8.6e-09 35.5 0.9 2.2 2 0 0 2 2 2 1 PH domain PH_4 PF15404.1 EKE39478.1 - 0.81 9.1 10.9 0.029 13.9 2.2 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Mcp5_PH PF12814.2 EKE39478.1 - 0.84 9.5 4.9 0.16 11.8 0.3 2.1 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology UEV PF05743.8 EKE39479.1 - 9.9e-18 63.9 0.6 2.3e-17 62.7 0.4 1.6 1 0 0 1 1 1 1 UEV domain DUF3288 PF11691.3 EKE39479.1 - 0.06 13.0 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) UQ_con PF00179.21 EKE39479.1 - 0.18 11.2 4.2 0.49 9.8 2.6 1.9 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKE39479.1 - 0.22 11.3 4.8 2.2 8.0 1.1 3.1 2 1 0 2 2 2 0 Prokaryotic E2 family B Maelstrom PF13017.1 EKE39480.1 - 3.6e-45 154.0 9.7 4.1e-45 153.9 6.7 1.0 1 0 0 1 1 1 1 piRNA pathway germ-plasm component Baculo_p48 PF04878.8 EKE39480.1 - 0.017 14.0 4.6 0.024 13.5 3.2 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein Erf4 PF10256.4 EKE39480.1 - 0.049 13.4 0.6 0.21 11.4 0.2 2.2 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family SIP1 PF04938.7 EKE39481.1 - 5.7e-08 32.4 0.0 7.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Glyco_trans_4_2 PF13477.1 EKE39482.1 - 0.081 12.7 0.2 0.17 11.6 0.0 1.6 2 1 0 2 2 2 0 Glycosyl transferase 4-like YcfA PF07927.7 EKE39482.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 YcfA-like protein LRR_5 PF13306.1 EKE39483.1 - 8.4e-46 154.8 23.0 4.9e-28 97.4 6.7 3.7 2 2 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE39483.1 - 1.1e-22 79.5 10.6 5.2e-09 35.7 0.6 5.2 3 2 3 6 6 6 5 Leucine rich repeat TPR_11 PF13414.1 EKE39485.1 - 1.4e-13 50.2 0.9 1.4e-13 50.2 0.6 3.2 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EKE39485.1 - 9.7e-11 40.8 9.6 6.7e-06 25.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKE39485.1 - 2.4e-09 36.3 7.1 0.0001 21.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE39485.1 - 7.8e-08 32.1 6.9 1.6e-05 24.7 0.9 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKE39485.1 - 6.4e-07 28.7 5.0 0.033 13.9 0.0 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKE39485.1 - 9.9e-06 24.9 4.1 0.038 13.7 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKE39485.1 - 0.00072 19.5 5.3 0.00074 19.5 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE39485.1 - 0.0017 18.6 0.5 0.18 12.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKE39485.1 - 0.029 15.0 0.6 12 6.9 0.0 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKE39485.1 - 0.037 14.6 0.3 0.17 12.5 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat NT-C2 PF10358.4 EKE39486.1 - 2.4e-17 62.7 2.1 5.2e-17 61.6 1.4 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EKE39486.1 - 2.4e-08 33.8 4.6 2e-07 30.8 0.8 2.7 2 0 0 2 2 2 2 DIL domain PseudoU_synth_1 PF01416.15 EKE39487.1 - 4.8e-18 65.5 0.8 8.2e-10 39.0 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase VSP PF03302.8 EKE39488.1 - 0.00012 20.9 46.7 0.0014 17.3 17.3 2.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein Metallophos_2 PF12850.2 EKE39489.1 - 1.1e-05 25.3 0.2 1.9e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EKE39489.1 - 0.00032 20.1 3.2 0.0012 18.2 2.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EKE39489.1 - 0.0031 16.7 0.1 0.013 14.6 0.0 2.0 2 1 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily KilA-N PF04383.8 EKE39489.1 - 0.039 13.5 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 KilA-N domain Collar PF07484.7 EKE39489.1 - 0.055 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Phage Tail Collar Domain CTD_bind PF04818.8 EKE39491.1 - 0.95 9.7 10.4 0.44 10.8 0.6 2.8 2 1 0 2 2 2 0 RNA polymerase II-binding domain. Pribosyltran_N PF13793.1 EKE39492.1 - 5.5e-21 74.4 0.1 8.8e-18 64.1 0.0 2.8 2 1 1 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EKE39492.1 - 2.9e-12 46.7 3.0 2.9e-12 46.7 2.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EKE39492.1 - 2.3e-07 30.5 0.1 3.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain IglC PF11550.3 EKE39492.1 - 0.025 13.8 0.1 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Intracellular growth locus C protein TGT PF01702.13 EKE39493.1 - 7e-80 267.7 0.0 9.3e-80 267.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PsiA PF06952.6 EKE39494.1 - 0.055 12.5 1.5 0.071 12.1 1.1 1.1 1 0 0 1 1 1 0 PsiA protein ENT PF03735.9 EKE39494.1 - 0.14 11.9 2.4 0.55 9.9 0.1 2.4 2 1 0 2 2 2 0 ENT domain Dermcidin PF15291.1 EKE39494.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Cor1 PF04803.7 EKE39494.1 - 0.48 10.1 5.0 1.3 8.7 3.5 1.7 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region CN_hydrolase PF00795.17 EKE39495.1 - 1.1e-16 60.7 0.0 1.7e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PI3_PI4_kinase PF00454.22 EKE39496.1 - 0.00046 19.7 0.2 0.00046 19.7 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase QueF_N PF14819.1 EKE39496.1 - 0.44 10.6 5.3 0.17 12.0 0.2 2.8 3 0 0 3 3 3 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Exo_endo_phos PF03372.18 EKE39497.1 - 2.4e-24 86.6 0.0 2.9e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EKE39497.1 - 2.7e-08 33.4 0.0 5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ResIII PF04851.10 EKE39498.1 - 1.1e-17 64.4 0.7 3.6e-17 62.8 0.5 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKE39498.1 - 1e-08 34.8 0.3 2.9e-08 33.3 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DNA_pol3_delta2 PF13177.1 EKE39498.1 - 1.5 8.4 7.8 0.17 11.5 0.3 2.6 2 1 0 2 2 2 0 DNA polymerase III, delta subunit Ribosomal_S19 PF00203.16 EKE39499.1 - 2.2e-29 100.8 1.1 3e-29 100.4 0.5 1.4 1 1 0 1 1 1 1 Ribosomal protein S19 RasGAP PF00616.14 EKE39500.1 - 0.0045 16.6 12.0 0.0049 16.5 7.2 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Ubiquitin_2 PF14560.1 EKE39500.1 - 0.023 14.9 0.2 0.054 13.7 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain PI3_PI4_kinase PF00454.22 EKE39501.1 - 5.3e-07 29.3 1.9 4.3e-05 23.1 1.3 3.3 1 1 1 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UBA_4 PF14555.1 EKE39501.1 - 0.087 12.3 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain Peptidase_M20 PF01546.23 EKE39502.1 - 3.5e-28 98.3 0.0 4.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EKE39502.1 - 6.5e-18 64.5 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EKE39502.1 - 2.6e-07 30.5 0.0 3.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 SH3_1 PF00018.23 EKE39504.1 - 2e-13 49.4 0.6 5.1e-13 48.1 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EKE39504.1 - 5e-12 45.2 0.1 1.2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE39504.1 - 1.1e-11 43.9 0.2 2.1e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EKE39504.1 - 4.5e-10 39.4 11.2 4.5e-10 39.4 7.7 2.2 1 1 0 2 2 2 1 BAR domain Barstar PF01337.13 EKE39504.1 - 0.11 12.3 0.5 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Fungal_trans_2 PF11951.3 EKE39504.1 - 0.83 8.1 3.5 5.5 5.4 2.5 2.2 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF3757 PF12582.3 EKE39504.1 - 1.1 9.4 7.0 0.4 10.8 2.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3757) zf-RING_2 PF13639.1 EKE39505.1 - 9.7e-14 50.9 9.6 1.3e-13 50.4 6.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE39505.1 - 6.2e-13 48.5 8.7 9.2e-13 47.9 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE39505.1 - 9.4e-13 47.6 6.7 1.4e-12 47.1 4.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE39505.1 - 1.2e-09 37.6 8.4 1.9e-09 37.0 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE39505.1 - 3.6e-09 36.1 7.2 6.9e-09 35.3 5.0 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EKE39505.1 - 2.1e-06 27.4 6.4 4e-06 26.5 4.1 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EKE39505.1 - 1.1e-05 24.8 3.4 1.8e-05 24.1 2.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EKE39505.1 - 1.3e-05 24.8 5.5 2.8e-05 23.7 0.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EKE39505.1 - 1.7e-05 24.7 10.0 3.8e-05 23.6 6.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 EKE39505.1 - 0.00014 21.1 3.5 0.00018 20.8 2.4 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 EKE39505.1 - 0.0032 17.0 7.5 0.0065 16.0 5.1 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EKE39505.1 - 0.0033 17.2 3.2 0.0051 16.6 2.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 EKE39505.1 - 0.0062 16.4 4.5 0.0091 15.9 3.1 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain zf-P11 PF03854.9 EKE39505.1 - 0.019 14.4 6.2 0.033 13.6 4.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 EKE39505.1 - 0.031 14.0 2.8 0.063 13.0 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 EKE39505.1 - 0.15 11.8 4.4 0.27 10.9 3.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1644 PF07800.7 EKE39505.1 - 0.38 10.5 4.2 2.2 8.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-Nse PF11789.3 EKE39505.1 - 0.54 9.8 4.2 0.85 9.1 2.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 EKE39505.1 - 0.65 9.8 7.5 1.9 8.3 5.2 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-CHY PF05495.7 EKE39505.1 - 0.73 10.0 7.3 1.2 9.3 5.1 1.3 1 0 0 1 1 1 0 CHY zinc finger IBR PF01485.16 EKE39505.1 - 0.82 9.5 11.4 1.3 8.9 6.4 2.3 1 1 1 2 2 2 0 IBR domain DUF1272 PF06906.6 EKE39505.1 - 0.97 9.3 7.6 5.6 6.8 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) FANCL_C PF11793.3 EKE39505.1 - 3.1 7.8 13.2 2e+02 2.0 9.1 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain C2 PF00168.25 EKE39506.1 - 1e-27 95.7 0.1 3.4e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain ThiF PF00899.16 EKE39507.1 - 7.8e-37 126.1 0.1 1.6e-36 125.1 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EKE39507.1 - 6.1e-25 86.5 0.4 2e-24 84.9 0.3 1.9 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EKE39507.1 - 1.8e-16 59.2 0.8 3.8e-16 58.2 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EKE39507.1 - 6.1e-12 45.4 1.3 1.4e-11 44.3 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EKE39507.1 - 0.00022 21.4 0.2 0.0012 19.0 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EKE39507.1 - 0.01 15.9 0.3 0.029 14.4 0.2 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1128 PF06569.6 EKE39507.1 - 0.051 13.2 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_12 PF13087.1 EKE39508.1 - 9.3e-55 185.1 0.0 3e-54 183.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKE39508.1 - 4.1e-47 160.7 0.6 4.1e-47 160.7 0.4 1.9 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.5 EKE39508.1 - 1e-26 93.3 10.9 1e-26 93.3 7.6 2.9 4 0 0 4 4 4 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 EKE39508.1 - 1.6e-12 46.9 0.1 4.6e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKE39508.1 - 4.6e-11 42.6 0.0 4.4e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EKE39508.1 - 2.4e-06 27.4 0.1 8.2e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EKE39508.1 - 0.0014 17.7 2.2 0.0018 17.3 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EKE39508.1 - 0.0015 17.8 0.0 0.003 16.8 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein SRP54 PF00448.17 EKE39508.1 - 0.0036 16.7 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.9 EKE39508.1 - 0.0076 15.9 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Helicase DEAD PF00270.24 EKE39508.1 - 0.01 15.3 1.5 0.075 12.5 1.1 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 EKE39508.1 - 0.033 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EKE39510.1 - 8e-52 175.9 0.3 1.9e-51 174.7 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39510.1 - 3.5e-44 150.8 0.2 5.5e-44 150.1 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.7 EKE39510.1 - 2.2e-43 145.7 22.7 1.8e-09 37.9 0.0 10.3 11 0 0 11 11 11 7 Sel1 repeat TPR_11 PF13414.1 EKE39510.1 - 0.0025 17.4 22.3 0.46 10.1 1.9 6.3 4 3 2 6 6 6 2 TPR repeat TPR_19 PF14559.1 EKE39510.1 - 0.0038 17.5 2.6 3.6 7.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EKE39510.1 - 0.025 14.7 14.1 0.29 11.2 0.6 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EKE39510.1 - 0.04 13.8 8.6 1.6 8.7 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Kdo PF06293.9 EKE39510.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_20 PF14561.1 EKE39510.1 - 0.18 11.9 0.0 0.59 10.2 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKE39510.1 - 0.3 11.0 27.6 0.075 12.9 0.4 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE39510.1 - 3.4 8.3 15.0 26 5.5 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat DER1 PF04511.10 EKE39511.1 - 2.8e-25 88.9 21.3 3.3e-25 88.7 14.8 1.1 1 0 0 1 1 1 1 Der1-like family Skp1 PF01466.14 EKE39513.1 - 2.6e-15 56.2 0.0 3.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EKE39513.1 - 3.5e-10 39.8 0.6 6.3e-10 38.9 0.4 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 EKE39513.1 - 0.07 13.1 0.0 1.2 9.1 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain RasGAP PF00616.14 EKE39514.1 - 2.6e-29 102.3 3.4 2.6e-29 102.3 2.4 3.0 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase TLD PF07534.11 EKE39515.1 - 2.4e-08 34.0 0.9 5.1e-08 33.0 0.6 1.6 1 0 0 1 1 1 1 TLD Toprim PF01751.17 EKE39515.1 - 0.032 14.1 0.7 0.11 12.4 0.3 2.1 1 1 1 2 2 2 0 Toprim domain SMC_Nse1 PF07574.8 EKE39515.1 - 0.036 13.6 1.9 0.058 13.0 1.3 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Toxin_59 PF15537.1 EKE39515.1 - 0.046 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 59 TPR_11 PF13414.1 EKE39517.1 - 1.5e-14 53.3 6.7 3.8e-14 52.0 1.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EKE39517.1 - 2.4e-10 39.5 9.3 0.00058 19.5 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKE39517.1 - 2.2e-08 33.3 12.2 1.1e-05 24.8 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE39517.1 - 1.9e-06 28.3 0.4 0.00022 21.8 0.0 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat RPAP3_C PF13877.1 EKE39517.1 - 8.3e-06 25.6 0.1 1.9e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_9 PF13371.1 EKE39517.1 - 0.0032 17.2 0.1 0.0088 15.8 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat B PF02216.11 EKE39517.1 - 0.0074 16.0 3.2 2.5 7.9 0.2 3.6 3 0 0 3 3 3 1 B domain Fis1_TPR_C PF14853.1 EKE39517.1 - 0.019 14.8 7.9 0.097 12.5 0.2 3.3 1 1 2 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EKE39517.1 - 0.028 14.1 12.1 1.1 9.2 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKE39517.1 - 0.031 14.4 2.4 9.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EKE39517.1 - 0.15 12.4 3.6 0.15 12.4 1.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EKE39517.1 - 0.24 11.5 3.2 0.26 11.4 0.3 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EKE39517.1 - 0.41 10.6 5.6 1.9 8.4 0.7 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Ras PF00071.17 EKE39518.1 - 1.9e-19 69.6 0.0 2.1e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39518.1 - 5.1e-12 46.3 0.0 7.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EKE39518.1 - 2.8e-05 23.4 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE39518.1 - 3.2e-05 23.4 0.3 0.017 14.6 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39518.1 - 0.0018 18.2 0.0 0.0026 17.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Vps53_N PF04100.7 EKE39518.1 - 0.0053 15.5 0.2 0.0078 15.0 0.2 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Septin PF00735.13 EKE39518.1 - 0.0083 15.1 0.4 0.015 14.3 0.1 1.7 1 1 1 2 2 2 1 Septin AAA_22 PF13401.1 EKE39518.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKE39518.1 - 0.086 13.0 0.2 13 6.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Daxx PF03344.10 EKE39519.1 - 3.4 6.0 51.6 4.1 5.7 35.8 1.1 1 0 0 1 1 1 0 Daxx Family RRM_1 PF00076.17 EKE39520.1 - 4.5e-39 131.9 3.4 1.2e-19 69.6 0.4 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39520.1 - 6.6e-27 93.2 1.0 3.6e-16 58.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39520.1 - 2.8e-19 68.7 0.2 3.2e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKE39520.1 - 0.00068 19.3 1.7 0.18 11.5 0.4 2.9 2 1 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 EKE39520.1 - 0.014 14.8 0.6 4.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EKE39520.1 - 0.037 13.7 0.1 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EKE39520.1 - 0.057 13.2 0.8 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 RNA binding motif Peripla_BP_4 PF13407.1 EKE39520.1 - 0.14 11.4 0.0 0.98 8.7 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein domain Ras PF00071.17 EKE39522.1 - 1.5e-26 92.7 0.2 1.7e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39522.1 - 6.3e-11 42.8 0.0 1.2e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39522.1 - 2.2e-05 23.7 0.1 2.7e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MobB PF03205.9 EKE39522.1 - 0.00013 21.6 0.1 0.0096 15.6 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 EKE39522.1 - 0.00015 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_22 PF13401.1 EKE39522.1 - 0.00023 21.3 0.0 0.00056 20.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain Bac_DnaA PF00308.13 EKE39522.1 - 0.00035 20.2 0.1 0.00043 19.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial dnaA protein ABC_tran PF00005.22 EKE39522.1 - 0.00066 19.9 0.0 0.0013 18.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA PF00004.24 EKE39522.1 - 0.00078 19.6 0.0 0.002 18.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE39522.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EKE39522.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EKE39522.1 - 0.0083 15.7 0.2 0.015 14.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EKE39522.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EKE39522.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 EKE39522.1 - 0.013 15.3 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EKE39522.1 - 0.022 13.4 0.6 0.035 12.7 0.4 1.6 1 1 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.4 EKE39522.1 - 0.026 14.0 0.1 0.051 13.0 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EKE39522.1 - 0.033 13.6 0.3 0.15 11.4 0.2 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EKE39522.1 - 0.035 14.4 0.0 0.082 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 EKE39522.1 - 0.042 12.6 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase AAA_14 PF13173.1 EKE39522.1 - 0.045 13.6 0.2 0.1 12.4 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 EKE39522.1 - 0.045 13.1 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EKE39522.1 - 0.049 14.4 3.3 0.18 12.6 2.3 2.1 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EKE39522.1 - 0.058 12.7 0.1 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.12 EKE39522.1 - 0.067 12.7 0.3 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EKE39522.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EKE39522.1 - 0.092 12.6 0.0 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EKE39522.1 - 0.16 12.2 3.6 0.87 9.8 2.5 1.9 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EKE39523.1 - 8.6e-19 67.4 0.1 1e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39523.1 - 0.00076 19.9 0.1 0.0013 19.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Lipase_GDSL PF00657.17 EKE39524.1 - 4.3e-06 26.7 0.0 4.3e-05 23.4 0.0 2.2 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKE39524.1 - 0.00044 20.4 0.0 0.0022 18.1 0.0 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family RNF111_N PF15303.1 EKE39524.1 - 0.0044 16.5 0.3 0.0064 16.0 0.2 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus Rad10 PF03834.9 EKE39524.1 - 0.24 11.1 1.4 0.5 10.0 0.1 2.1 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) RhoGAP PF00620.22 EKE39525.1 - 8.5e-32 109.8 0.0 1.9e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain CD20 PF04103.10 EKE39526.1 - 0.014 15.3 3.9 0.027 14.3 2.6 1.7 1 1 0 1 1 1 0 CD20-like family Claudin_2 PF13903.1 EKE39526.1 - 0.018 14.7 4.0 0.7 9.5 1.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction NT-C2 PF10358.4 EKE39527.1 - 4.5e-20 71.5 0.2 4.5e-20 71.5 0.1 4.8 4 2 1 5 5 5 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EKE39527.1 - 7.4e-11 41.8 1.9 9e-10 38.3 0.6 3.1 2 0 0 2 2 2 1 DIL domain Biliv-reduc_cat PF09166.5 EKE39528.1 - 0.005 16.8 0.2 0.0097 15.9 0.2 1.4 1 0 0 1 1 1 1 Biliverdin reductase, catalytic Ku_C PF03730.9 EKE39528.1 - 0.023 15.2 2.6 0.043 14.3 1.8 1.4 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm CHD5 PF04420.9 EKE39528.1 - 0.037 13.7 0.8 0.073 12.7 0.6 1.5 1 0 0 1 1 1 0 CHD5-like protein TM1506 PF08973.5 EKE39528.1 - 0.041 13.4 0.6 0.15 11.5 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) MtrB PF05440.7 EKE39529.1 - 0.12 12.4 0.2 0.12 12.4 0.1 4.2 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B SHNi-TPR PF10516.4 EKE39529.1 - 0.37 10.0 5.8 0.44 9.8 0.3 3.5 3 0 0 3 3 3 0 SHNi-TPR DUF2428 PF10350.4 EKE39530.1 - 1.8e-09 36.9 0.0 6.3e-09 35.2 0.0 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) PAP2 PF01569.16 EKE39531.1 - 0.001 18.7 5.8 0.001 18.7 4.0 2.3 1 1 0 2 2 2 1 PAP2 superfamily RRM_1 PF00076.17 EKE39532.1 - 7.4e-81 265.7 15.6 4.4e-19 67.8 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39532.1 - 1.9e-68 226.4 9.5 8.7e-15 54.4 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39532.1 - 5.2e-51 170.3 9.4 3.6e-11 42.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE39532.1 - 4.7e-10 39.0 1.1 0.29 10.9 0.0 5.5 5 0 0 5 5 5 4 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EKE39532.1 - 9e-09 34.9 8.8 0.12 12.1 0.0 6.5 5 2 1 6 6 6 4 Limkain b1 RRM_2 PF04059.7 EKE39532.1 - 0.0001 22.2 4.7 0.075 13.0 0.1 4.0 4 0 0 4 4 4 2 RNA recognition motif 2 MGS PF02142.17 EKE39532.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.2 4 0 0 4 4 4 0 MGS-like domain OB_RNB PF08206.6 EKE39532.1 - 0.16 11.5 5.8 26 4.4 0.1 4.4 4 0 0 4 4 4 0 Ribonuclease B OB domain Ribosomal_L35Ae PF01247.13 EKE39533.1 - 1.1e-35 121.2 0.3 1.2e-35 121.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EKE39533.1 - 0.022 14.7 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain Pkinase PF00069.20 EKE39534.1 - 2.4e-71 239.9 0.4 3.1e-71 239.5 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39534.1 - 1.3e-39 135.8 0.1 1.7e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKE39534.1 - 9.6e-13 48.0 1.0 2.2e-12 46.9 0.7 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EKE39534.1 - 3.3e-08 32.8 0.0 4.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EKE39534.1 - 0.0063 15.8 0.1 0.015 14.6 0.1 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EKE39534.1 - 0.018 14.3 0.1 0.091 12.0 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EKE39534.1 - 0.022 13.8 0.1 0.039 13.0 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE39534.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DENN PF02141.16 EKE39535.1 - 2.5e-19 69.7 7.4 5.8e-19 68.5 5.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF939 PF06081.6 EKE39535.1 - 0.0086 15.9 0.7 0.0086 15.9 0.5 1.8 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF939) SPA PF08616.5 EKE39535.1 - 0.022 14.4 1.2 0.052 13.2 0.8 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis TGT_C1 PF14809.1 EKE39535.1 - 0.081 12.7 2.4 0.12 12.1 0.0 2.5 3 0 0 3 3 3 0 C1 domain of tRNA-guanine transglycosylase dimerisation dDENN PF03455.14 EKE39535.1 - 0.15 12.1 4.5 0.13 12.3 1.6 2.0 2 0 0 2 2 2 0 dDENN domain OB_NTP_bind PF07717.11 EKE39536.1 - 4.8e-20 71.5 0.1 9.7e-20 70.5 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKE39536.1 - 6e-19 67.9 0.1 1.2e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKE39536.1 - 3.1e-13 49.3 0.0 1.3e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE39536.1 - 1.7e-09 37.3 0.4 4.2e-09 36.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE39536.1 - 1.7e-05 24.9 0.1 4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EKE39536.1 - 0.0029 17.8 0.2 0.016 15.5 0.1 2.1 1 1 0 1 1 1 1 ABC transporter ResIII PF04851.10 EKE39536.1 - 0.0052 16.6 0.0 4.7 6.9 0.0 2.7 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EKE39536.1 - 0.0056 16.4 0.1 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EKE39536.1 - 0.0071 15.2 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EKE39536.1 - 0.037 13.5 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 EKE39536.1 - 0.04 13.0 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 EKE39536.1 - 0.046 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EKE39536.1 - 0.058 13.3 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKE39536.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ParcG PF10274.4 EKE39537.1 - 0.018 14.9 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Parkin co-regulated protein Vps39_2 PF10367.4 EKE39537.1 - 0.03 14.4 0.6 0.037 14.1 0.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 HemX PF04375.9 EKE39537.1 - 0.097 11.2 1.1 0.12 10.9 0.7 1.1 1 0 0 1 1 1 0 HemX Endonuclease_7 PF02945.10 EKE39537.1 - 0.27 10.9 4.4 0.68 9.6 3.1 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII EF-1_beta_acid PF10587.4 EKE39537.1 - 9.7 6.4 9.2 7.2 6.8 0.6 2.3 1 1 1 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Endonuc_subdom PF09062.5 EKE39538.1 - 0.11 13.2 2.4 13 6.6 0.1 3.4 2 1 1 3 3 3 0 PI-PfuI Endonuclease subdomain Med6 PF04934.9 EKE39539.1 - 2.2e-05 24.0 3.7 0.00025 20.5 2.6 2.0 1 1 0 1 1 1 1 MED6 mediator sub complex component DNA_pol_phi PF04931.8 EKE39540.1 - 9.2e-15 53.5 38.7 1.4e-08 33.0 0.5 3.3 2 1 1 3 3 3 3 DNA polymerase phi DUF3492 PF11997.3 EKE39540.1 - 0.19 11.2 4.1 0.23 10.9 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Pkinase PF00069.20 EKE39542.1 - 4.2e-62 209.6 0.2 6.6e-62 209.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39542.1 - 3.4e-50 170.5 0.1 5.5e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE39542.1 - 1.5e-24 86.1 17.4 5.4e-13 49.0 0.4 3.9 4 0 0 4 4 4 3 PH domain PH_11 PF15413.1 EKE39542.1 - 3.1e-08 33.8 14.6 0.00012 22.2 1.5 4.7 3 2 0 3 3 3 2 Pleckstrin homology domain Kinase-like PF14531.1 EKE39542.1 - 1.4e-07 30.7 0.0 8.4e-06 24.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PH_8 PF15409.1 EKE39542.1 - 2.6e-06 27.4 1.0 0.0033 17.4 0.0 3.0 2 0 0 2 2 2 2 Pleckstrin homology domain PBD PF00786.23 EKE39542.1 - 0.023 15.0 0.2 0.066 13.6 0.1 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain Kdo PF06293.9 EKE39542.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3791 PF12668.2 EKE39545.1 - 0.098 12.2 0.6 0.21 11.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) UCH PF00443.24 EKE39545.1 - 2.9 6.9 13.1 2.7e+02 0.4 9.0 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase SPG48 PF14764.1 EKE39546.1 - 1.2e-19 70.2 3.8 1.8e-18 66.3 2.6 2.4 1 1 0 1 1 1 1 AP-5 complex subunit, vesicle trafficking Alkyl_sulf_dimr PF14863.1 EKE39547.1 - 1.4e-59 200.3 1.0 2.3e-59 199.6 0.7 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 EKE39547.1 - 9.2e-20 71.1 0.0 2e-19 69.9 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 EKE39547.1 - 1.9e-17 63.4 0.2 3.4e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.2 EKE39547.1 - 1e-07 31.7 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_11 PF13414.1 EKE39547.1 - 0.00029 20.4 0.7 0.00068 19.2 0.5 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 EKE39547.1 - 0.00091 19.8 0.4 0.0017 18.9 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat SCP2 PF02036.12 EKE39547.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Apc3 PF12895.2 EKE39547.1 - 0.053 13.6 0.1 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Metallophos PF00149.23 EKE39548.1 - 2.5e-25 89.0 0.3 3.5e-25 88.5 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_19 PF12844.2 EKE39551.1 - 0.00015 21.7 0.1 0.00055 19.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.17 EKE39551.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Pkinase PF00069.20 EKE39552.1 - 3.5e-36 124.7 1.2 6.6e-36 123.7 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39552.1 - 2.7e-22 79.1 0.0 5.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE39552.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3987 PF13148.1 EKE39553.1 - 1.1 7.7 4.1 1.9 6.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1806 PF08830.5 EKE39554.1 - 0.4 10.5 2.3 0.99 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1806) EF-hand_7 PF13499.1 EKE39556.1 - 2.6e-16 59.4 8.6 9e-07 28.9 0.9 4.6 4 2 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EKE39556.1 - 3.1e-14 51.1 9.0 0.00083 18.5 0.0 6.0 8 0 0 8 8 8 3 EF hand EF-hand_6 PF13405.1 EKE39556.1 - 2.3e-12 45.6 5.6 0.0059 16.3 0.0 6.2 7 0 0 7 7 7 3 EF-hand domain EF-hand_5 PF13202.1 EKE39556.1 - 1.1e-09 37.1 1.9 0.096 12.0 0.1 4.0 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EKE39556.1 - 5.3e-08 32.3 6.3 0.051 13.1 0.2 5.4 5 1 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKE39556.1 - 0.0064 16.5 3.1 0.22 11.5 0.1 3.2 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region SinI PF08671.5 EKE39556.1 - 0.13 11.7 2.1 6.2 6.3 0.0 3.2 3 0 0 3 3 3 0 Anti-repressor SinI EF-hand_4 PF12763.2 EKE39556.1 - 0.15 11.7 1.9 1.5 8.6 0.1 2.8 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EKE39556.1 - 2 8.1 7.8 5.1 6.8 0.0 4.0 4 0 0 4 4 4 0 EF hand tRNA_m1G_MT PF01746.16 EKE39557.1 - 3.9e-22 78.7 0.1 3.9e-22 78.7 0.1 1.8 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase XOO_2897-deam PF14440.1 EKE39557.1 - 0.065 12.9 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Thioredoxin_8 PF13905.1 EKE39557.1 - 0.076 13.1 1.7 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like PI3K_1B_p101 PF10486.4 EKE39557.1 - 0.11 9.9 2.4 0.15 9.5 1.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PEHE PF15275.1 EKE39557.1 - 0.69 10.3 10.8 2.3 8.7 6.6 2.5 2 1 0 2 2 2 0 PEHE domain DUF2228 PF10228.4 EKE39557.1 - 0.69 9.4 8.3 1.5 8.3 5.8 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUF1765 PF08578.5 EKE39558.1 - 7.6e-14 51.8 6.1 7.6e-14 51.8 4.3 3.9 4 1 0 4 4 4 1 Protein of unknown function (DUF1765) Trs65 PF12735.2 EKE39559.1 - 3.2e-06 26.6 0.1 3.2e-06 26.6 0.1 2.8 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 STT3 PF02516.9 EKE39560.1 - 1.5e-97 327.5 41.8 9.7e-95 318.3 29.0 2.2 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 EKE39560.1 - 0.01 15.7 16.4 0.01 15.7 11.4 4.4 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF912 PF06024.7 EKE39560.1 - 0.023 14.7 1.0 0.023 14.7 0.7 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) tRNA-synt_2d PF01409.15 EKE39561.1 - 2.4e-85 285.6 0.0 3.1e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EKE39561.1 - 3.9e-06 25.8 2.3 0.0015 17.3 0.0 3.6 4 0 0 4 4 4 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EKE39561.1 - 0.00052 19.6 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Bac_surface_Ag PF01103.18 EKE39562.1 - 2.7e-08 33.6 0.0 4.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Surface antigen PCI PF01399.22 EKE39563.1 - 6.8e-12 45.6 2.6 2.7e-11 43.7 0.3 2.3 2 1 0 2 2 2 1 PCI domain Pkinase PF00069.20 EKE39564.1 - 5.2e-61 206.0 1.0 1e-60 205.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39564.1 - 4e-33 114.5 0.0 8.5e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE39564.1 - 7.2e-10 39.0 2.8 1.1e-09 38.4 0.2 2.7 2 1 0 2 2 2 1 PH domain APH PF01636.18 EKE39564.1 - 5.3e-06 26.3 0.0 0.015 15.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EKE39564.1 - 0.001 18.0 0.0 0.0029 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EKE39564.1 - 0.0057 16.0 0.1 0.017 14.4 0.0 1.8 1 0 0 1 1 1 1 RIO1 family PH_11 PF15413.1 EKE39564.1 - 0.018 15.2 1.1 0.13 12.5 0.8 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain DUF2296 PF10058.4 EKE39564.1 - 0.6 9.8 6.3 1.8 8.3 4.4 1.9 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF1765 PF08578.5 EKE39565.1 - 9.9e-15 54.7 15.1 2.3e-14 53.5 10.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Sld5 PF05916.6 EKE39565.1 - 0.0084 16.3 1.8 0.14 12.4 0.5 3.0 1 1 1 2 2 2 1 GINS complex protein RCSD PF05177.7 EKE39566.1 - 2.6 8.5 20.7 6.9 7.2 14.3 1.8 1 1 0 1 1 1 0 RCSD region Fzo_mitofusin PF04799.8 EKE39566.1 - 3.4 7.0 17.0 0.057 12.8 1.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region Pkinase_Tyr PF07714.12 EKE39568.1 - 2.6e-39 134.8 0.1 5.4e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39568.1 - 9.7e-35 119.9 1.0 5e-34 117.6 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.2 EKE39568.1 - 1.2e-18 66.3 39.9 1e-07 31.3 2.1 6.7 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE39568.1 - 2e-15 56.2 35.7 1.2e-06 28.1 1.3 6.2 3 2 3 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 EKE39568.1 - 7.4e-06 25.3 15.2 21 5.9 0.5 9.0 8 0 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 EKE39568.1 - 1.1e-05 24.7 32.5 0.49 10.6 0.9 9.7 9 0 0 9 9 9 2 Leucine Rich Repeat Myotub-related PF06602.9 EKE39568.1 - 0.00041 19.2 5.4 0.00069 18.4 2.6 2.0 1 1 1 2 2 2 1 Myotubularin-like phosphatase domain LRR_6 PF13516.1 EKE39568.1 - 0.0076 16.2 34.7 0.3 11.2 1.5 9.3 9 0 0 9 9 9 1 Leucine Rich repeat APH PF01636.18 EKE39568.1 - 0.91 9.2 0.0 1.6 8.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EKE39569.1 - 5.9e-46 156.6 0.0 1.8e-45 155.0 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39569.1 - 1.1e-43 149.3 0.0 2.6e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EKE39569.1 - 1.6e-16 60.3 3.2 6.8e-10 39.1 0.4 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKE39569.1 - 1.7e-16 60.1 1.7 0.011 16.2 0.1 5.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE39569.1 - 2.3e-12 46.7 1.0 2.4e-06 27.6 0.3 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EKE39569.1 - 4.8e-12 45.0 1.4 0.047 13.5 0.1 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 EKE39569.1 - 5.1e-10 38.6 2.4 0.0093 16.1 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat APH PF01636.18 EKE39569.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family P-II PF00543.17 EKE39569.1 - 0.17 12.3 2.3 0.25 11.8 0.6 2.0 2 0 0 2 2 2 0 Nitrogen regulatory protein P-II NAP PF00956.13 EKE39570.1 - 8.5e-21 74.1 17.8 8e-20 71.0 12.3 2.0 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DnaI_N PF07319.6 EKE39570.1 - 1.9 8.8 9.5 0.66 10.2 2.1 2.8 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Sec7 PF01369.15 EKE39571.1 - 3.8e-40 137.6 5.9 3.8e-40 137.6 4.1 2.8 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EKE39571.1 - 2.3e-14 53.1 2.5 2.3e-14 53.1 1.7 3.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-MYND PF01753.13 EKE39571.1 - 0.0011 18.7 9.8 0.0011 18.7 6.8 1.8 2 0 0 2 2 2 1 MYND finger DUF1981 PF09324.5 EKE39571.1 - 0.0013 18.2 0.4 0.0013 18.2 0.3 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) zf-HIT PF04438.11 EKE39571.1 - 0.0037 16.8 8.6 0.0037 16.8 5.9 2.1 2 0 0 2 2 2 1 HIT zinc finger Renin_r PF07850.9 EKE39572.1 - 0.038 14.3 1.5 0.043 14.1 1.0 1.2 1 0 0 1 1 1 0 Renin receptor-like protein EI24 PF07264.6 EKE39572.1 - 0.042 13.2 0.4 0.043 13.2 0.3 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) TMEM156 PF15106.1 EKE39572.1 - 0.064 12.4 0.6 0.07 12.3 0.4 1.2 1 0 0 1 1 1 0 TMEM156 protein family ABC2_membrane_2 PF12679.2 EKE39572.1 - 0.12 11.1 2.4 0.15 10.9 1.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Baculo_11_kDa PF06143.6 EKE39572.1 - 0.14 11.5 1.5 0.15 11.4 1.1 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3139 PF11337.3 EKE39572.1 - 0.43 10.8 5.4 0.16 12.2 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) SP_C-Propep PF08999.5 EKE39572.1 - 4.9 6.7 7.1 5.7 6.4 4.6 1.3 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide Ras PF00071.17 EKE39573.1 - 7.1e-49 165.3 1.3 8.2e-49 165.1 0.9 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE39573.1 - 3.8e-20 71.8 0.7 4.6e-20 71.5 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE39573.1 - 1.1e-18 67.7 0.1 1.6e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKE39573.1 - 6.1e-08 32.0 0.1 7.3e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE39573.1 - 7.1e-06 25.3 0.1 9.7e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE39573.1 - 1.3e-05 24.7 1.4 9.9e-05 21.8 0.9 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39573.1 - 0.00037 20.4 0.2 0.00053 19.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE39573.1 - 0.0009 19.3 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE39573.1 - 0.0063 16.2 0.1 0.0083 15.8 0.1 1.1 1 0 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 EKE39573.1 - 0.025 14.9 0.3 0.037 14.3 0.2 1.3 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EKE39573.1 - 0.026 14.1 0.2 0.23 11.0 0.0 2.3 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.4 EKE39573.1 - 0.063 12.7 1.2 0.27 10.7 0.8 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EKE39573.1 - 0.074 12.6 0.1 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EKE39573.1 - 0.095 12.1 0.0 0.18 11.3 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 EKE39573.1 - 0.14 11.6 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EKE39573.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Mg-por_mtran_C PF07109.6 EKE39574.1 - 0.057 13.4 0.3 0.15 12.1 0.2 1.7 1 1 1 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus LPAM_1 PF08139.7 EKE39574.1 - 2.2 8.6 6.5 0.67 10.2 1.5 2.1 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site RRF PF01765.14 EKE39574.1 - 3.6 7.0 9.1 0.94 8.9 0.3 2.3 2 1 0 2 2 2 0 Ribosome recycling factor Pkinase_Tyr PF07714.12 EKE39575.1 - 6.7e-35 120.3 0.2 1.4e-34 119.3 0.2 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39575.1 - 1.3e-32 112.9 0.4 1.3e-32 112.9 0.2 2.4 3 0 0 3 3 3 1 Protein kinase domain LRR_4 PF12799.2 EKE39575.1 - 1.4e-17 62.8 33.0 1.1e-07 31.2 0.2 6.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) Myotub-related PF06602.9 EKE39575.1 - 4.9e-14 51.8 3.7 1.2e-13 50.6 2.6 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain LRR_8 PF13855.1 EKE39575.1 - 1.2e-13 50.5 31.0 2.3e-07 30.4 0.7 4.8 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 EKE39575.1 - 2.4e-07 29.8 27.2 0.099 12.7 0.4 8.7 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 EKE39575.1 - 0.00091 19.0 28.7 0.25 11.6 0.7 8.1 7 0 0 7 7 7 3 Leucine rich repeat GRAM PF02893.15 EKE39575.1 - 0.0016 17.9 0.6 0.01 15.3 0.0 2.6 2 0 0 2 2 2 1 GRAM domain Kdo PF06293.9 EKE39575.1 - 0.051 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.1 EKE39575.1 - 6.5 7.1 35.9 0.69 10.1 0.2 7.4 6 1 1 7 7 7 0 Leucine Rich repeat TLD PF07534.11 EKE39577.1 - 1.9e-06 27.8 0.3 3.1e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 TLD CCDC-167 PF15188.1 EKE39577.1 - 0.019 14.8 9.4 0.04 13.8 6.5 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 YppF PF14178.1 EKE39577.1 - 0.057 12.9 3.3 0.11 12.0 2.3 1.5 1 0 0 1 1 1 0 YppF-like protein Pox_A_type_inc PF04508.7 EKE39577.1 - 1 9.3 3.9 1.2 9.0 0.4 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RRM_1 PF00076.17 EKE39578.1 - 9.1e-22 76.4 0.5 1.4e-21 75.8 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39578.1 - 1.6e-14 53.6 0.1 2.5e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39578.1 - 2.1e-08 33.8 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EKE39578.1 - 0.0038 16.6 1.3 0.019 14.4 0.9 2.2 1 1 0 1 1 1 1 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EKE39578.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EKE39578.1 - 0.041 13.7 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif PP2C_2 PF13672.1 EKE39580.1 - 1.2e-09 37.9 0.0 2.2e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE39580.1 - 0.0066 16.1 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) SecE PF00584.15 EKE39582.1 - 6.3e-14 51.2 0.0 7e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CPSF_A PF03178.10 EKE39583.1 - 5.3e-43 147.3 0.8 5.3e-43 147.3 0.6 3.2 4 0 0 4 4 4 1 CPSF A subunit region MMS1_N PF10433.4 EKE39583.1 - 6.5e-21 74.0 5.8 1.5e-20 72.8 4.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CAF1 PF04857.15 EKE39584.1 - 4.8e-59 199.8 0.9 6.7e-59 199.3 0.7 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Mucin PF01456.12 EKE39585.1 - 0.0082 15.9 3.3 0.0082 15.9 2.3 1.7 1 1 1 2 2 2 1 Mucin-like glycoprotein Pup PF05639.6 EKE39585.1 - 3.1 8.3 5.0 2.3 8.7 1.0 2.2 2 0 0 2 2 2 0 Pup-like protein Helicase_C_2 PF13307.1 EKE39586.1 - 1.3e-43 148.7 0.0 2.5e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1227 PF06777.6 EKE39586.1 - 0.00063 19.4 1.4 0.0049 16.5 0.9 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EKE39586.1 - 0.0069 15.8 0.1 0.038 13.3 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 Cytomega_gL PF01801.11 EKE39586.1 - 0.0073 15.8 0.1 0.018 14.5 0.1 1.6 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein L DEAD_2 PF06733.10 EKE39587.1 - 9.2e-17 60.9 1.0 1.2e-16 60.6 0.7 1.1 1 0 0 1 1 1 1 DEAD_2 HSP70 PF00012.15 EKE39588.1 - 2.2e-126 422.2 14.9 4.3e-123 411.3 3.9 3.0 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EKE39588.1 - 5.4e-09 35.0 5.3 1.7e-08 33.4 0.1 3.5 3 1 0 3 3 3 1 MreB/Mbl protein Caldesmon PF02029.10 EKE39588.1 - 1.9 6.8 50.6 2.9 6.2 35.1 1.1 1 0 0 1 1 1 0 Caldesmon DUF2514 PF10721.4 EKE39588.1 - 2.9 7.5 13.6 4.7 6.8 8.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) RR_TM4-6 PF06459.7 EKE39588.1 - 3.8 7.3 34.0 6 6.6 12.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FtsA PF14450.1 EKE39588.1 - 7.6 6.4 7.5 3.6 7.4 0.2 3.4 2 2 0 2 2 2 0 Cell division protein FtsA Ank_2 PF12796.2 EKE39589.1 - 3.5e-52 174.7 3.4 7.3e-12 45.4 0.0 7.2 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE39589.1 - 3e-43 144.8 0.2 5.5e-08 32.8 0.0 10.9 3 2 9 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.25 EKE39589.1 - 1.2e-42 141.6 4.5 6.4e-06 25.7 0.1 11.8 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 EKE39589.1 - 1.4e-38 130.5 6.9 3.6e-05 24.1 0.0 10.2 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE39589.1 - 6.6e-32 106.3 11.5 0.00045 20.1 0.0 11.5 12 0 0 12 12 12 8 Ankyrin repeat Shigella_OspC PF06128.6 EKE39589.1 - 0.0035 16.9 1.7 2.1 7.7 0.0 3.3 3 1 1 4 4 4 2 Shigella flexneri OspC protein zf-RING_2 PF13639.1 EKE39590.1 - 1.2e-10 41.0 10.4 2.8e-10 39.8 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKE39590.1 - 1.5e-06 27.7 8.8 3.4e-06 26.6 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE39590.1 - 5e-06 26.1 10.4 5e-06 26.1 7.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE39590.1 - 3.7e-05 23.6 9.3 3.7e-05 23.6 6.4 2.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE39590.1 - 0.00039 20.0 10.8 0.00039 20.0 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKE39590.1 - 0.0013 18.7 6.0 0.0013 18.7 4.2 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EKE39590.1 - 0.0036 17.1 3.8 0.0075 16.0 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EKE39590.1 - 0.04 13.6 8.8 0.064 12.9 2.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger TP_methylase PF00590.15 EKE39591.1 - 2e-20 73.4 0.0 2.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases EMP24_GP25L PF01105.19 EKE39591.1 - 0.04 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PH PF00169.24 EKE39592.1 - 2.8e-10 40.2 0.0 9.6e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EKE39592.1 - 0.003 17.5 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EKE39592.1 - 0.019 15.2 1.3 0.019 15.2 0.9 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain Herpes_LMP2 PF07415.6 EKE39592.1 - 0.73 8.3 4.5 1.1 7.7 3.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Tetraspannin PF00335.15 EKE39593.1 - 1.3e-08 34.4 10.6 2.2e-08 33.6 7.4 1.3 1 1 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 EKE39593.1 - 0.02 14.5 15.9 0.26 10.9 6.7 2.6 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 EKE39593.1 - 0.43 10.5 15.8 0.42 10.5 8.4 2.4 1 1 1 2 2 2 0 CD20-like family YfhO PF09586.5 EKE39593.1 - 0.67 7.8 8.4 0.33 8.9 4.4 1.4 1 1 0 1 1 1 0 Bacterial membrane protein YfhO VirB8 PF04335.8 EKE39593.1 - 1.4 8.4 5.0 0.45 10.0 0.7 2.0 1 1 0 2 2 2 0 VirB8 protein Peptidase_M20 PF01546.23 EKE39595.1 - 8.5e-19 67.7 0.0 1.5e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EKE39595.1 - 2.3e-05 23.3 0.4 0.44 9.2 0.0 3.2 3 0 0 3 3 3 3 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 EKE39595.1 - 0.001 18.8 0.2 0.0071 16.1 0.2 2.3 2 1 0 2 2 2 1 Peptidase family M28 Pkinase PF00069.20 EKE39596.1 - 2.1e-57 194.2 1.1 2.8e-57 193.8 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39596.1 - 2.2e-30 105.5 0.2 4.2e-30 104.6 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39596.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EKE39596.1 - 0.0058 16.2 3.3 0.0098 15.4 2.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKE39596.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKE39596.1 - 0.017 14.3 0.3 0.031 13.4 0.2 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 EKE39596.1 - 0.024 13.7 0.1 0.047 12.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EKE39596.1 - 0.024 13.3 4.7 0.76 8.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) TLD PF07534.11 EKE39597.1 - 0.00038 20.4 0.2 0.00063 19.7 0.1 1.4 1 0 0 1 1 1 1 TLD DUF2004 PF09406.5 EKE39597.1 - 0.076 13.0 0.5 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) RIH_assoc PF08454.6 EKE39597.1 - 4.2 7.0 8.7 2.6 7.7 4.6 1.6 2 0 0 2 2 2 0 RyR and IP3R Homology associated Na_H_Exchanger PF00999.16 EKE39599.1 - 5.4e-50 170.0 48.6 6.9e-50 169.6 33.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ABA_GPCR PF12430.3 EKE39599.1 - 0.0076 15.4 6.9 0.0076 15.4 4.8 3.1 3 1 0 3 3 3 1 Abscisic acid G-protein coupled receptor Metallophos PF00149.23 EKE39600.1 - 1e-36 126.2 0.2 1.3e-36 125.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE39600.1 - 0.00034 20.4 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LacAB_rpiB PF02502.13 EKE39602.1 - 4.9e-55 185.0 0.6 5.6e-55 184.8 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2024 PF09630.5 EKE39602.1 - 0.024 14.3 0.2 2.7 7.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2024) PTS_IIB PF02302.12 EKE39602.1 - 0.17 12.3 1.1 1.6 9.2 0.7 2.6 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Profilin PF00235.14 EKE39603.1 - 7.8e-30 103.4 1.8 8.7e-30 103.3 1.3 1.0 1 0 0 1 1 1 1 Profilin Lyase_1 PF00206.15 EKE39604.1 - 3.8e-94 315.3 0.0 4.8e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EKE39604.1 - 2.3e-21 75.6 0.1 6.3e-21 74.2 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus bZIP_Maf PF03131.12 EKE39605.1 - 0.025 14.8 1.6 0.025 14.8 1.1 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Syntaxin PF00804.20 EKE39605.1 - 0.051 13.7 3.8 3.9 7.6 2.6 2.1 1 1 0 1 1 1 0 Syntaxin CaM_bdg_C0 PF10562.4 EKE39605.1 - 0.12 12.2 2.3 0.31 10.9 1.6 1.7 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit PACT_coil_coil PF10495.4 EKE39605.1 - 0.13 12.2 2.5 0.14 12.1 0.7 1.7 1 1 1 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Antimicrobial_7 PF08102.6 EKE39605.1 - 0.15 12.0 3.1 8.5 6.4 0.1 2.4 2 1 0 2 2 2 0 Scorpion antimicrobial peptide bZIP_1 PF00170.16 EKE39605.1 - 2.8 7.9 9.5 16 5.5 6.5 2.2 1 1 0 1 1 1 0 bZIP transcription factor CDC27 PF09507.5 EKE39606.1 - 0.016 14.4 62.2 0.024 13.8 43.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 EKE39606.1 - 0.1 12.4 57.8 0.14 11.9 40.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase_Tyr PF07714.12 EKE39607.1 - 2e-36 125.3 0.1 2.6e-36 125.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39607.1 - 2.1e-31 108.9 0.1 3.3e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Motile_Sperm PF00635.21 EKE39607.1 - 0.066 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Rifin_STEVOR PF02009.11 EKE39607.1 - 0.096 12.3 4.3 0.22 11.1 3.0 1.6 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EKE39607.1 - 0.12 12.7 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FbpA PF05833.6 EKE39608.1 - 1.7e-38 132.3 25.8 1.7e-38 132.3 17.9 3.3 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EKE39608.1 - 3.1e-21 75.0 0.1 1e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 EKE39608.1 - 2.3e-19 69.0 0.0 2.3e-19 69.0 0.0 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3441) zf-CCHC PF00098.18 EKE39608.1 - 6.6e-06 25.8 0.5 1.8e-05 24.4 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EKE39608.1 - 0.0063 16.1 0.6 0.0063 16.1 0.4 2.7 2 0 0 2 2 2 1 Zinc knuckle Metalloenzyme PF01676.13 EKE39610.1 - 4.3e-34 118.0 0.0 4.7e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EKE39610.1 - 9.4e-07 28.4 0.0 1.1e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.15 EKE39610.1 - 0.00011 21.0 0.0 0.00017 20.4 0.0 1.4 1 1 1 2 2 2 1 Alkaline phosphatase Ras PF00071.17 EKE39611.1 - 5.5e-50 168.9 0.0 6.9e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39611.1 - 5e-18 65.7 0.0 8.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39611.1 - 1.1e-09 37.7 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39611.1 - 2.6e-05 23.7 0.2 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39611.1 - 0.0042 17.0 0.0 0.0075 16.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE39611.1 - 0.025 13.8 0.1 0.063 12.4 0.0 1.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKE39611.1 - 0.096 12.1 0.4 4.2 6.8 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FH2 PF02181.18 EKE39612.1 - 1.4e-66 224.9 11.8 1.4e-66 224.9 8.2 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Reo_sigmaC PF04582.7 EKE39612.1 - 0.035 13.2 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein GBP_C PF02841.9 EKE39612.1 - 1.5 7.9 28.8 0.8 8.8 18.0 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Nucleoporin2 PF04096.9 EKE39613.1 - 1e-20 74.0 0.2 1e-20 74.0 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin autopeptidase Ras PF00071.17 EKE39614.1 - 1.7e-64 216.0 1.2 2e-64 215.8 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39614.1 - 1.3e-19 70.7 0.3 4.6e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39614.1 - 4.5e-18 65.1 0.6 5.9e-18 64.7 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39614.1 - 5.2e-09 35.5 0.3 6.1e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE39614.1 - 7.2e-06 25.3 0.2 1.3e-05 24.4 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE39614.1 - 1e-05 25.0 0.4 2e-05 24.0 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39614.1 - 6.4e-05 22.8 0.1 0.00012 21.9 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE39614.1 - 0.0012 18.9 0.0 0.0036 17.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EKE39614.1 - 0.0021 17.3 0.7 0.0051 16.1 0.5 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EKE39614.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EKE39614.1 - 0.012 15.0 0.5 2.2 7.7 0.1 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EKE39614.1 - 0.014 14.4 0.1 0.029 13.4 0.0 1.5 2 0 0 2 2 2 0 Septin AAA PF00004.24 EKE39614.1 - 0.017 15.3 0.1 0.28 11.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EKE39614.1 - 0.027 13.6 0.0 0.054 12.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EKE39614.1 - 0.037 13.7 0.1 0.09 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EKE39614.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EKE39614.1 - 0.064 13.5 0.2 0.1 12.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EKE39614.1 - 0.32 9.6 2.6 7 5.2 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Apyrase PF06079.6 EKE39616.1 - 8.7e-10 38.2 0.1 7.2e-09 35.2 0.1 2.0 1 1 0 1 1 1 1 Apyrase CDC37_M PF08565.6 EKE39617.1 - 7.5e-07 28.8 0.3 1.2e-06 28.1 0.1 1.3 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain LRR_8 PF13855.1 EKE39618.1 - 0.02 14.6 16.0 0.29 10.8 0.1 5.5 5 1 0 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 EKE39618.1 - 0.021 14.9 2.1 1e+02 3.7 0.0 5.5 4 0 0 4 4 4 0 Leucine rich repeat LIM PF00412.17 EKE39619.1 - 2.4e-42 142.8 54.1 2.7e-13 49.7 6.9 4.1 4 0 0 4 4 4 4 LIM domain DUF2724 PF10893.3 EKE39619.1 - 0.36 10.7 2.5 24 4.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2724) DZR PF12773.2 EKE39619.1 - 0.93 9.3 51.7 0.56 10.0 0.4 6.5 2 1 3 5 5 5 0 Double zinc ribbon PNTB PF02233.11 EKE39621.1 - 4.4e-68 230.1 0.4 4.8e-68 230.0 0.3 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit YihI PF04220.7 EKE39622.1 - 0.12 11.6 0.3 0.21 10.8 0.0 1.4 2 0 0 2 2 2 0 Der GTPase activator (YihI) Tudor-knot PF11717.3 EKE39622.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Fer2_BFD PF04324.10 EKE39623.1 - 0.027 14.5 0.1 5.9 7.0 0.0 3.5 2 1 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF3250 PF11618.3 EKE39624.1 - 2.2 8.5 4.3 37 4.5 0.0 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF3250) Rhodanese PF00581.15 EKE39625.1 - 1.1e-11 45.1 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_8 PF08022.7 EKE39625.1 - 0.17 11.7 0.7 0.65 9.8 0.0 2.2 2 1 1 3 3 3 0 FAD-binding domain TMEM154 PF15102.1 EKE39626.1 - 1.3e-05 24.9 0.3 1.3e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 TMEM154 protein family Podoplanin PF05808.6 EKE39626.1 - 0.00019 21.0 2.1 0.00039 20.0 1.5 1.5 1 0 0 1 1 1 1 Podoplanin Renin_r PF07850.9 EKE39626.1 - 0.0004 20.6 0.2 0.0013 19.0 0.1 1.9 1 0 0 1 1 1 1 Renin receptor-like protein Rifin_STEVOR PF02009.11 EKE39626.1 - 0.00062 19.5 1.3 0.00062 19.5 0.9 1.7 1 1 1 2 2 2 1 Rifin/stevor family DUF912 PF06024.7 EKE39626.1 - 0.00073 19.5 6.1 0.00073 19.5 4.2 2.5 2 1 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4366 PF14283.1 EKE39626.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2023 PF09633.5 EKE39626.1 - 0.046 13.6 0.8 1.8 8.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2023) P12 PF12669.2 EKE39626.1 - 1.4 9.1 4.8 3.6 7.8 3.3 1.8 1 0 0 1 1 1 0 Virus attachment protein p12 family DNA_pol_viral_N PF00242.12 EKE39626.1 - 2.8 6.8 9.4 3.9 6.4 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain HSP70 PF00012.15 EKE39627.1 - 2e-70 237.4 1.1 4.7e-70 236.1 0.7 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE39627.1 - 9e-09 34.3 0.5 9e-09 34.3 0.4 3.0 3 1 0 3 3 3 1 MreB/Mbl protein RRM_5 PF13893.1 EKE39628.1 - 3e-08 33.3 0.3 2.4e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE39628.1 - 1.4e-07 31.0 0.0 1.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39628.1 - 0.0038 17.1 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EKE39628.1 - 0.0059 16.2 4.6 0.1 12.3 0.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleocapsid-N PF11030.3 EKE39628.1 - 0.023 14.5 2.2 0.034 13.9 1.5 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N DDT PF02791.12 EKE39629.1 - 0.0073 16.0 0.0 0.025 14.3 0.0 1.9 1 0 0 1 1 1 1 DDT domain TFIIA PF03153.8 EKE39629.1 - 1.5 8.6 27.7 2.6 7.8 19.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 EKE39629.1 - 3.6 5.7 8.5 4.5 5.3 5.9 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DcpS_C PF11969.3 EKE39630.1 - 1.7e-15 57.2 1.0 6e-15 55.4 0.0 2.2 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Fe-ADH PF00465.14 EKE39631.1 - 1.6e-50 171.8 0.0 2e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Drf_FH3 PF06367.11 EKE39632.1 - 1.8e-10 40.5 2.3 1.8e-10 40.5 1.6 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Arm PF00514.18 EKE39632.1 - 0.012 15.3 0.6 10 6.1 0.1 3.2 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat CppA_N PF14506.1 EKE39632.1 - 0.3 10.7 5.6 0.25 11.0 0.6 2.3 1 1 1 2 2 2 0 CppA N-terminal DUF3502 PF12010.3 EKE39633.1 - 0.036 14.0 1.4 0.063 13.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) Borrelia_REV PF03978.8 EKE39633.1 - 0.095 12.4 3.8 0.16 11.6 2.4 1.5 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein Dus PF01207.12 EKE39634.1 - 1.3e-66 224.5 0.2 1.5e-66 224.3 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EKE39634.1 - 2.5e-07 29.9 0.0 5.6e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.15 EKE39634.1 - 0.0082 15.1 0.1 0.014 14.3 0.1 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HEAT_2 PF13646.1 EKE39635.1 - 0.017 15.3 0.0 1.5 9.1 0.0 3.4 2 1 0 2 2 2 0 HEAT repeats Arm PF00514.18 EKE39635.1 - 0.024 14.4 1.9 71 3.4 0.1 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HSF_DNA-bind PF00447.12 EKE39636.1 - 8.6e-30 102.9 2.7 8.6e-30 102.9 1.9 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding YPEB PF14620.1 EKE39636.1 - 0.011 14.7 0.4 0.015 14.3 0.3 1.2 1 0 0 1 1 1 0 YpeB sporulation Lactamase_B PF00753.22 EKE39637.1 - 9.7e-15 54.7 0.0 2.6e-14 53.3 0.0 1.6 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Flavodoxin_1 PF00258.20 EKE39637.1 - 2.7e-10 40.3 0.0 2.1e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 EKE39637.1 - 0.00065 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain DUF1256 PF06866.6 EKE39637.1 - 0.0049 16.0 0.8 0.3 10.2 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1256) Ras PF00071.17 EKE39639.1 - 9.4e-51 171.4 0.5 1.5e-50 170.7 0.4 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39639.1 - 1.8e-12 47.7 0.1 1.8e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39639.1 - 1e-10 41.1 0.0 1.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39639.1 - 2.6e-06 27.0 0.1 0.00016 21.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE39639.1 - 3.6e-05 23.0 0.1 5.4e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE39639.1 - 7.5e-05 22.0 1.6 8.3e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE39639.1 - 0.00018 21.4 0.3 0.00035 20.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKE39639.1 - 0.00073 18.7 0.3 0.0019 17.4 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKE39639.1 - 0.0027 17.8 0.1 0.0059 16.7 0.0 1.7 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EKE39639.1 - 0.0039 17.1 0.8 0.0078 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKE39639.1 - 0.0071 16.6 0.1 0.015 15.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain Septin PF00735.13 EKE39639.1 - 0.0077 15.2 0.0 0.0077 15.2 0.0 1.8 2 0 0 2 2 2 1 Septin AAA PF00004.24 EKE39639.1 - 0.0079 16.4 0.1 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EKE39639.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain CPT PF07931.7 EKE39639.1 - 0.0095 15.5 0.1 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.12 EKE39639.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EKE39639.1 - 0.013 16.3 0.1 0.018 15.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKE39639.1 - 0.014 15.3 0.1 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EKE39639.1 - 0.016 14.6 0.1 0.11 11.8 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EKE39639.1 - 0.016 15.3 0.1 0.031 14.4 0.1 1.7 1 1 0 1 1 1 0 RNA helicase MobB PF03205.9 EKE39639.1 - 0.032 13.9 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EKE39639.1 - 0.035 13.9 0.8 0.14 12.0 0.0 2.1 2 1 0 3 3 3 0 AAA domain Torsin PF06309.6 EKE39639.1 - 0.042 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Torsin PduV-EutP PF10662.4 EKE39639.1 - 0.068 12.6 1.4 0.35 10.3 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Hpr_kinase_C PF07475.7 EKE39639.1 - 0.084 12.1 0.3 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AIG1 PF04548.11 EKE39639.1 - 0.14 11.2 5.0 0.24 10.4 0.2 2.4 2 1 0 2 2 2 0 AIG1 family Ank_2 PF12796.2 EKE39641.1 - 1.6e-74 246.3 8.7 9.2e-15 54.7 0.0 8.0 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKE39641.1 - 9.7e-65 213.9 18.1 7.8e-09 35.8 0.0 11.7 4 3 10 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE39641.1 - 2e-63 208.9 10.0 6.7e-08 32.5 0.0 13.1 5 3 8 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.25 EKE39641.1 - 4.1e-62 203.0 11.3 5.7e-06 25.8 0.0 14.4 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.1 EKE39641.1 - 6.4e-56 180.7 17.3 0.00062 19.7 0.0 14.6 14 1 0 14 14 14 12 Ankyrin repeat Hexapep PF00132.19 EKE39641.1 - 7.1e-15 53.7 18.7 3.3e-10 39.0 3.2 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKE39641.1 - 3.7e-11 42.3 18.1 3.9e-06 26.3 1.7 3.5 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EKE39641.1 - 0.0077 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Peptidase_C23 PF05379.6 EKE39641.1 - 0.012 15.5 0.0 0.063 13.2 0.0 2.3 2 0 0 2 2 2 0 Carlavirus endopeptidase DUF3447 PF11929.3 EKE39641.1 - 0.038 13.7 0.0 0.038 13.7 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) zf-DHHC PF01529.15 EKE39642.1 - 2.3e-22 79.2 17.6 2.3e-22 79.2 12.2 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 EKE39642.1 - 0.34 10.2 5.4 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.17 EKE39643.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OmpH PF03938.9 EKE39644.1 - 0.094 12.6 2.4 0.11 12.3 1.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DinI PF06183.8 EKE39644.1 - 0.097 12.7 0.6 0.23 11.5 0.4 1.6 1 0 0 1 1 1 0 DinI-like family Bap31 PF05529.7 EKE39644.1 - 1.8 8.0 3.9 2.5 7.5 2.7 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 EKE39644.1 - 3.5 7.1 4.9 4.3 6.8 3.4 1.1 1 0 0 1 1 1 0 IncA protein Lactamase_B_3 PF13483.1 EKE39646.1 - 2.2e-23 82.7 1.1 2.5e-23 82.5 0.7 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EKE39646.1 - 1.5e-15 57.2 0.9 2e-15 56.8 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF787 PF05619.6 EKE39646.1 - 0.0008 18.1 0.1 0.0011 17.7 0.1 1.2 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF787) Lactamase_B PF00753.22 EKE39646.1 - 0.34 10.5 4.0 2.7 7.5 1.8 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Macro PF01661.16 EKE39647.1 - 8.9e-31 106.2 0.4 2e-30 105.1 0.3 1.6 1 0 0 1 1 1 1 Macro domain zf-RING_2 PF13639.1 EKE39649.1 - 3.6e-08 33.1 9.9 3.6e-08 33.1 6.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE39649.1 - 9.7e-07 28.7 9.1 9.7e-07 28.7 6.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE39649.1 - 1.1e-06 28.1 8.9 1.1e-06 28.1 6.2 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE39649.1 - 1.9e-06 27.4 6.8 1.9e-06 27.4 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKE39649.1 - 1.2e-05 25.2 11.0 4.3e-05 23.5 7.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EKE39649.1 - 5.2e-05 22.8 8.4 5.2e-05 22.8 5.8 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKE39649.1 - 0.0002 21.1 7.0 0.00078 19.2 5.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EKE39649.1 - 0.0073 15.8 5.0 0.016 14.7 3.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EKE39649.1 - 0.081 12.6 8.1 0.072 12.8 1.9 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EKE39649.1 - 4.3 6.9 9.3 1.4 8.5 3.8 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prismane PF03063.15 EKE39650.1 - 8.6e-148 492.9 1.1 9.6e-148 492.7 0.8 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family Ada_Zn_binding PF02805.11 EKE39650.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Metal binding domain of Ada UPF0261 PF06792.6 EKE39650.1 - 0.029 12.8 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) PRK PF00485.13 EKE39651.1 - 3.3e-16 59.4 0.1 1.1e-15 57.7 0.0 2.0 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EKE39651.1 - 4.6e-07 30.6 0.0 1.3e-06 29.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKE39651.1 - 7.9e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EKE39651.1 - 0.00013 21.7 0.1 0.0034 17.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EKE39651.1 - 0.00078 19.7 0.1 0.0034 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKE39651.1 - 0.0016 17.9 0.1 0.14 11.5 0.0 3.1 3 1 1 4 4 4 1 AAA-like domain KTI12 PF08433.5 EKE39651.1 - 0.027 13.6 0.0 0.055 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 EKE39651.1 - 0.035 13.0 0.1 0.25 10.2 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_35 PF14516.1 EKE39651.1 - 0.054 12.1 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 EKE39651.1 - 0.06 12.7 0.3 0.38 10.1 0.0 2.3 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EKE39651.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Lebercilin PF15619.1 EKE39651.1 - 0.11 11.9 1.3 0.18 11.1 0.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Abhydrolase_5 PF12695.2 EKE39652.1 - 2.2e-17 63.1 0.0 2.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE39652.1 - 1.7e-08 34.6 0.0 0.0039 17.0 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKE39652.1 - 4.8e-08 32.4 0.0 1e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EKE39652.1 - 5.5e-06 26.1 0.1 0.033 13.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKE39652.1 - 8.6e-05 22.0 0.6 0.014 14.8 0.5 3.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EKE39652.1 - 0.0027 16.6 0.0 0.0072 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) FSH1 PF03959.8 EKE39652.1 - 0.0034 16.8 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 EKE39652.1 - 0.007 15.6 0.0 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family LIP PF03583.9 EKE39652.1 - 0.014 14.6 0.1 0.07 12.3 0.0 1.9 1 1 1 2 2 2 0 Secretory lipase DUF1057 PF06342.7 EKE39652.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) AAA PF00004.24 EKE39654.1 - 3.9e-51 172.7 0.1 4.7e-40 136.8 0.0 3.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EKE39654.1 - 8.2e-08 32.6 0.3 0.014 15.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EKE39654.1 - 7.8e-07 29.9 0.0 0.086 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EKE39654.1 - 9.3e-07 28.9 0.0 0.022 14.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.9 EKE39654.1 - 4e-06 26.8 0.1 5.2e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EKE39654.1 - 1.5e-05 24.8 0.5 0.15 11.9 0.0 3.2 4 0 0 4 4 2 2 AAA domain IstB_IS21 PF01695.12 EKE39654.1 - 1.5e-05 24.4 0.3 0.14 11.5 0.0 3.0 4 0 0 4 4 3 2 IstB-like ATP binding protein AAA_22 PF13401.1 EKE39654.1 - 2.1e-05 24.6 5.8 0.012 15.7 0.5 4.1 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKE39654.1 - 2.5e-05 23.9 0.2 0.013 15.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EKE39654.1 - 2.6e-05 23.1 0.1 0.03 13.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_N PF02359.13 EKE39654.1 - 2.7e-05 24.0 0.0 9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Zeta_toxin PF06414.7 EKE39654.1 - 4e-05 22.8 1.5 0.037 13.1 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EKE39654.1 - 7.2e-05 22.2 2.0 0.27 10.6 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EKE39654.1 - 9.3e-05 22.4 0.5 0.079 12.9 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.9 EKE39654.1 - 0.00012 21.2 0.2 0.23 10.4 0.0 3.2 3 0 0 3 3 3 1 KAP family P-loop domain Sigma54_activat PF00158.21 EKE39654.1 - 0.00012 21.5 0.1 0.27 10.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.7 EKE39654.1 - 0.00013 21.1 0.1 0.026 13.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EKE39654.1 - 0.00018 21.2 4.9 1.8 8.1 0.1 4.7 5 1 0 5 5 4 1 NACHT domain KaiC PF06745.8 EKE39654.1 - 0.00023 20.3 0.3 0.015 14.3 0.1 2.6 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.17 EKE39654.1 - 0.00029 19.7 2.2 0.39 9.5 0.1 2.9 3 0 0 3 3 3 2 NB-ARC domain AAA_33 PF13671.1 EKE39654.1 - 0.0004 20.2 0.0 0.69 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EKE39654.1 - 0.00059 19.1 1.7 0.14 11.3 0.4 2.5 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EKE39654.1 - 0.00063 19.2 0.7 0.47 9.9 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EKE39654.1 - 0.00065 18.9 0.4 0.0045 16.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EKE39654.1 - 0.0007 19.2 2.2 0.16 11.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EKE39654.1 - 0.003 17.2 2.8 1.8 8.2 0.0 3.9 2 2 1 4 4 4 1 Archaeal ATPase AAA_19 PF13245.1 EKE39654.1 - 0.0061 16.2 1.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EKE39654.1 - 0.007 16.6 1.4 0.18 12.1 0.1 2.8 2 1 0 2 2 2 1 ABC transporter UPF0079 PF02367.12 EKE39654.1 - 0.01 15.4 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 EKE39654.1 - 0.043 12.9 0.2 0.4 9.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 EKE39654.1 - 0.043 12.7 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.4 EKE39654.1 - 0.056 12.3 2.0 9.8 4.9 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activ_2 PF14532.1 EKE39654.1 - 0.088 12.8 0.0 6 6.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CDC48_2 PF02933.12 EKE39654.1 - 0.18 11.4 1.0 0.39 10.3 0.1 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 RasGEF PF00617.14 EKE39655.1 - 1.4e-36 125.9 4.5 3.6e-36 124.6 2.5 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE39655.1 - 5e-13 49.0 5.9 8.1e-12 45.1 0.1 3.5 3 0 0 3 3 3 2 RasGEF N-terminal motif Metallophos PF00149.23 EKE39656.1 - 1.3e-37 129.1 0.1 1.6e-37 128.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE39656.1 - 1.9e-05 24.5 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4024 PF13216.1 EKE39656.1 - 0.1 12.4 0.6 0.28 11.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) Lactamase_B_2 PF12706.2 EKE39657.1 - 0.00017 21.1 0.5 0.0007 19.1 0.3 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2655 PF10848.3 EKE39657.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) CDP-OH_P_transf PF01066.16 EKE39658.1 - 1.1e-18 67.3 4.6 1.1e-18 67.3 3.2 3.3 2 1 1 3 3 3 1 CDP-alcohol phosphatidyltransferase Rep_fac-A_C PF08646.5 EKE39659.1 - 1.6e-11 44.0 5.2 1.6e-11 44.0 3.6 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EKE39659.1 - 3.2e-08 33.3 5.9 0.00033 20.4 0.0 4.0 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain AMMECR1 PF01871.12 EKE39660.1 - 2.8e-37 127.4 0.0 3.1e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Rhodanese PF00581.15 EKE39661.1 - 1.5e-10 41.3 0.0 2.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Imm24 PF15570.1 EKE39661.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 24 MFS_1 PF07690.11 EKE39662.1 - 5.6e-32 110.8 27.1 9e-21 73.9 3.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1162 PF06650.7 EKE39663.1 - 4.8e-15 55.4 10.7 2e-14 53.4 0.5 4.7 5 0 0 5 5 5 2 Protein of unknown function (DUF1162) ATG_C PF09333.6 EKE39663.1 - 5.7e-06 26.4 0.0 1.9e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain ENTH PF01417.15 EKE39664.1 - 0.0027 17.5 0.2 0.007 16.2 0.2 1.6 1 0 0 1 1 1 1 ENTH domain LSM14 PF12701.2 EKE39664.1 - 0.034 13.9 0.1 1.7 8.5 0.1 2.5 1 1 0 1 1 1 0 Scd6-like Sm domain CN_hydrolase PF00795.17 EKE39665.1 - 2.8e-17 62.6 0.0 4.2e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LRR_8 PF13855.1 EKE39666.1 - 8.8e-27 92.6 25.6 3e-10 39.7 1.3 3.3 1 1 3 4 4 4 4 Leucine rich repeat DnaJ PF00226.26 EKE39666.1 - 6.3e-25 86.7 4.6 6.3e-25 86.7 3.2 2.1 2 0 0 2 2 2 1 DnaJ domain LRR_4 PF12799.2 EKE39666.1 - 1.7e-15 56.2 9.3 2.7e-07 30.0 0.4 3.5 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EKE39666.1 - 5.1e-10 37.9 8.2 0.1 12.7 0.0 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_5 PF13306.1 EKE39666.1 - 6e-07 29.2 7.3 1.5e-06 27.9 5.1 1.7 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EKE39666.1 - 1.1e-05 24.9 6.6 1.3 9.3 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EKE39666.1 - 0.00013 21.5 2.8 1.7 9.2 0.0 4.8 5 0 0 5 5 5 2 Leucine rich repeat DUF3557 PF12078.3 EKE39666.1 - 0.03 14.0 2.6 0.14 11.8 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3557) EFhand_Ca_insen PF08726.5 EKE39666.1 - 0.045 13.7 0.1 1.7 8.6 0.0 2.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand CotJB PF12652.2 EKE39666.1 - 0.32 11.0 5.3 0.1 12.7 0.6 2.5 2 1 1 3 3 3 0 CotJB protein DNA_pol_B PF00136.16 EKE39667.1 - 2.7e-83 280.3 2.3 5.9e-83 279.1 1.6 1.5 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 EKE39667.1 - 3.1e-08 33.4 11.7 1.7e-07 31.1 8.1 2.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF3961 PF13106.1 EKE39668.1 - 0.46 10.0 5.9 8 6.1 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) zf-C2H2_2 PF12756.2 EKE39669.1 - 0.0011 19.0 0.3 0.002 18.2 0.2 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EKE39669.1 - 0.0086 16.1 0.6 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF1322 PF07032.6 EKE39669.1 - 0.4 10.8 5.4 0.36 11.0 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1322) DUF3244 PF11589.3 EKE39670.1 - 0.11 12.1 0.7 2.5 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3244) RhoGEF PF00621.15 EKE39671.1 - 2.1e-44 151.5 9.1 2.1e-44 151.5 6.3 2.0 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EKE39671.1 - 2.6e-16 59.2 11.6 7.3e-16 57.8 8.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE39671.1 - 1.7e-07 31.3 3.7 1.8e-07 31.3 0.6 2.6 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.11 EKE39671.1 - 3.4e-05 23.7 7.4 0.0001 22.2 5.2 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger PH_11 PF15413.1 EKE39671.1 - 0.037 14.2 1.3 0.13 12.5 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain Patatin PF01734.17 EKE39672.1 - 7.4e-20 71.7 0.0 2.4e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Ank_2 PF12796.2 EKE39672.1 - 1.6e-13 50.7 0.0 3.4e-07 30.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKE39672.1 - 8.3e-11 42.1 0.0 0.007 16.8 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EKE39672.1 - 5.7e-07 29.0 0.0 0.0048 16.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EKE39672.1 - 1.8e-06 27.9 0.0 0.00064 19.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE39672.1 - 3e-05 23.8 0.0 1.2 9.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Osmo_CC PF08946.5 EKE39672.1 - 1.3 9.0 8.3 0.13 12.2 0.6 3.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Pkinase PF00069.20 EKE39673.1 - 1.4e-60 204.6 0.0 1.8e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39673.1 - 4.6e-30 104.5 0.0 6.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39673.1 - 0.0024 16.8 0.1 0.012 14.6 0.0 2.1 3 0 0 3 3 3 1 Kinase-like YrbL-PhoP_reg PF10707.4 EKE39673.1 - 0.052 12.8 0.1 0.088 12.1 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FERM_M PF00373.13 EKE39674.1 - 4.8e-08 33.2 0.1 6.6e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 FERM central domain LRR_4 PF12799.2 EKE39674.1 - 2e-07 30.5 24.4 0.0004 19.9 0.3 7.5 5 3 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EKE39674.1 - 2.6e-06 26.6 13.7 4.2 7.7 1.0 8.9 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 EKE39674.1 - 3.4e-06 26.3 4.1 36 5.2 0.2 8.7 8 0 0 8 8 8 0 Leucine rich repeat LRR_6 PF13516.1 EKE39674.1 - 0.0015 18.3 37.1 1.7 8.9 0.9 11.7 12 0 0 12 12 12 2 Leucine Rich repeat LRR_8 PF13855.1 EKE39674.1 - 0.015 15.0 23.6 0.13 12.0 0.9 6.5 4 1 2 6 6 6 0 Leucine rich repeat ComX PF05952.7 EKE39674.1 - 0.036 13.5 1.1 2.8 7.5 0.0 3.6 4 0 0 4 4 4 0 Bacillus competence pheromone ComX Telomere_Sde2 PF13019.1 EKE39674.1 - 0.063 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Telomere stability and silencing Ras PF00071.17 EKE39675.1 - 1.4e-09 37.5 0.2 1.8e-09 37.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39675.1 - 1.7e-05 25.2 0.1 3.4e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39675.1 - 0.00032 19.9 0.1 0.00044 19.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_pol_A_bac PF01000.21 EKE39676.1 - 1.9e-20 73.1 0.1 1.2e-18 67.2 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EKE39676.1 - 9.2e-12 43.9 0.0 1.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_10 PF13237.1 EKE39676.1 - 0.06 13.1 2.0 0.12 12.2 1.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKE39676.1 - 0.7 10.1 5.1 2 8.7 3.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain PP2C PF00481.16 EKE39677.1 - 1.7e-53 181.6 0.0 2.2e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EKE39677.1 - 4.8e-39 131.3 93.3 7.4e-06 25.4 0.4 12.8 4 2 8 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE39677.1 - 5.1e-32 109.4 71.2 7e-08 32.1 7.0 9.2 5 2 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 EKE39677.1 - 2.2e-20 69.5 85.7 0.0066 16.3 0.2 18.9 18 2 1 19 19 19 11 Leucine Rich Repeat LRR_7 PF13504.1 EKE39677.1 - 1.1e-13 48.8 55.5 0.31 11.4 0.0 17.8 19 0 0 19 19 19 4 Leucine rich repeat LRR_6 PF13516.1 EKE39677.1 - 6.6e-05 22.5 68.0 0.55 10.4 0.3 15.5 12 4 5 17 17 17 5 Leucine Rich repeat PP2C_2 PF13672.1 EKE39677.1 - 0.00034 20.0 0.0 0.00092 18.6 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Choline_transpo PF04515.7 EKE39679.1 - 6.3e-56 189.5 32.3 6.3e-56 189.5 22.4 2.5 2 1 1 3 3 3 2 Plasma-membrane choline transporter RasGAP PF00616.14 EKE39680.1 - 2.6e-40 138.2 3.1 2.6e-40 138.2 2.2 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EKE39680.1 - 0.0039 17.1 0.8 0.0039 17.1 0.6 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF4656 PF15551.1 EKE39680.1 - 0.23 10.6 0.2 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4656) Pox_MCEL PF03291.11 EKE39681.1 - 2.6e-63 213.9 6.8 8.7e-63 212.1 4.7 1.6 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.1 EKE39681.1 - 1.4e-06 28.5 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE39681.1 - 1.8e-06 27.6 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE39681.1 - 2.4e-06 27.9 0.0 4.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE39681.1 - 7.4e-06 26.3 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EKE39681.1 - 0.00062 18.8 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EKE39681.1 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 EKE39681.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Proteasom_Rpn13 PF04683.8 EKE39682.1 - 4.6e-08 33.0 0.5 1.2e-07 31.7 0.3 1.7 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2073 PF09846.4 EKE39682.1 - 0.055 13.1 1.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) Peptidase_S10 PF00450.17 EKE39682.1 - 0.11 11.6 0.2 1.6 7.8 0.1 2.0 1 1 1 2 2 2 0 Serine carboxypeptidase Hexapep PF00132.19 EKE39684.1 - 1.2e-10 40.4 8.5 3.4e-07 29.4 1.6 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.9 EKE39684.1 - 0.0031 17.7 0.1 0.0068 16.6 0.0 1.6 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.1 EKE39684.1 - 0.093 12.3 7.9 0.18 11.4 0.5 3.0 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Thioredoxin PF00085.15 EKE39685.1 - 1.9e-31 107.8 0.0 1.8e-22 78.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EKE39685.1 - 7.9e-10 38.8 0.1 0.15 11.8 0.1 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EKE39685.1 - 5.1e-09 36.3 0.2 0.0017 18.5 0.1 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKE39685.1 - 1.1e-07 31.8 0.3 0.024 14.7 0.0 4.2 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_3 PF13192.1 EKE39685.1 - 1.7e-06 27.7 0.0 0.083 12.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_7 PF13899.1 EKE39685.1 - 1.6e-05 24.8 0.0 5e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EKE39685.1 - 0.004 16.8 0.1 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EKE39685.1 - 0.0051 16.3 0.0 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.12 EKE39685.1 - 0.067 11.9 0.1 8.7 4.9 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin Transposase_22 PF02994.9 EKE39686.1 - 0.058 11.8 0.2 0.056 11.9 0.1 1.0 1 0 0 1 1 1 0 L1 transposable element ubiquitin PF00240.18 EKE39687.1 - 1.6e-14 53.0 5.1 3.6e-14 51.9 3.6 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE39687.1 - 3e-07 30.0 2.5 1.3e-06 28.0 1.8 2.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EKE39687.1 - 0.00035 20.4 2.4 0.0013 18.6 1.7 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKE39687.1 - 0.019 15.2 4.2 0.025 14.8 1.8 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain PB1 PF00564.19 EKE39687.1 - 0.056 13.1 2.1 0.63 9.7 0.1 3.2 1 1 1 3 3 3 0 PB1 domain DUF2407 PF10302.4 EKE39687.1 - 0.16 12.2 7.6 0.32 11.2 5.3 1.9 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF3987 PF13148.1 EKE39687.1 - 3.9 5.9 6.2 0.26 9.7 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) E7 PF00527.13 EKE39687.1 - 4.8 7.4 6.7 2.2 8.5 2.0 2.4 2 1 0 2 2 2 0 E7 protein, Early protein Sre PF03125.13 EKE39688.1 - 1.2 7.9 18.3 4.1 6.2 12.7 1.7 1 1 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor RhoGAP PF00620.22 EKE39689.1 - 4.4e-40 136.7 0.0 8.1e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Avl9 PF09794.4 EKE39690.1 - 1.4e-11 43.5 6.3 7.7e-09 34.5 0.1 2.7 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EKE39690.1 - 5.2e-07 29.3 0.1 1.8e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 EKE39690.1 - 0.00025 20.4 0.1 0.00025 20.4 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) NUDE_C PF04880.8 EKE39691.1 - 5.8e-05 23.5 4.9 7.2e-05 23.2 3.4 1.1 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region DUF1875 PF08961.5 EKE39691.1 - 0.00085 18.7 1.5 0.0015 17.9 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) Mcm10 PF09332.6 EKE39691.1 - 0.0031 16.9 4.5 0.0039 16.5 3.1 1.2 1 0 0 1 1 1 1 Mcm10 replication factor GAS PF13851.1 EKE39691.1 - 0.0077 15.4 7.8 0.014 14.6 5.4 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF390 PF04094.9 EKE39691.1 - 0.0082 14.2 3.0 0.0079 14.3 1.7 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF390) Borrelia_P83 PF05262.6 EKE39691.1 - 0.012 13.9 1.0 0.01 14.1 0.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-C4H2 PF10146.4 EKE39691.1 - 0.015 15.3 6.7 0.015 15.3 4.6 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein DUF972 PF06156.8 EKE39691.1 - 0.02 15.2 4.6 0.02 15.2 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EKE39691.1 - 0.026 13.9 10.2 0.043 13.2 6.2 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EKE39691.1 - 0.031 14.5 10.4 0.031 14.5 7.2 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 EKE39691.1 - 0.041 13.5 12.5 0.29 10.8 4.4 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper ERM PF00769.14 EKE39691.1 - 0.043 13.3 14.9 0.068 12.7 10.3 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CAP_N PF01213.14 EKE39691.1 - 0.048 12.9 3.6 0.058 12.6 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WXG100 PF06013.7 EKE39691.1 - 0.059 13.3 0.9 0.11 12.5 0.6 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG V_ATPase_I PF01496.14 EKE39691.1 - 0.089 10.6 0.3 0.071 10.9 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mito_fiss_reg PF05308.6 EKE39691.1 - 0.11 11.8 6.8 0.14 11.5 4.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator BLOC1_2 PF10046.4 EKE39691.1 - 0.11 12.6 2.3 0.19 11.8 1.6 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EKE39691.1 - 0.2 10.6 10.2 0.33 9.9 7.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3186 PF11382.3 EKE39691.1 - 0.23 10.5 3.9 0.47 9.5 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) UPF0449 PF15136.1 EKE39691.1 - 0.44 10.7 4.1 1.4 9.1 2.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF2381 PF09544.5 EKE39691.1 - 0.58 9.2 7.5 0.28 10.2 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) PV-1 PF06637.6 EKE39691.1 - 1.2 7.6 5.5 2.3 6.6 3.8 1.5 1 1 0 1 1 1 0 PV-1 protein (PLVAP) HAUS6_N PF14661.1 EKE39691.1 - 1.2 8.3 5.8 2.1 7.6 4.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Mnd1 PF03962.10 EKE39691.1 - 1.5 8.4 7.8 2.6 7.6 5.4 1.3 1 0 0 1 1 1 0 Mnd1 family Cwf_Cwc_15 PF04889.7 EKE39691.1 - 2.6 7.7 13.4 2.3 7.8 5.3 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4337 PF14235.1 EKE39691.1 - 3.6 7.3 13.1 0.53 10.1 5.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Radial_spoke_3 PF06098.6 EKE39691.1 - 5.2 5.9 11.6 9.1 5.1 8.1 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Ras PF00071.17 EKE39692.1 - 5.4e-53 178.6 0.6 6.5e-53 178.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39692.1 - 4.3e-16 59.4 0.2 8.4e-16 58.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39692.1 - 3.2e-11 42.7 0.1 3.8e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39692.1 - 5e-07 29.3 0.1 9.1e-07 28.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain HVSL PF09749.4 EKE39692.1 - 0.064 12.2 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein EHN PF06441.7 EKE39692.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus HECT PF00632.20 EKE39693.1 - 5.3e-67 226.2 3.4 1.1e-66 225.2 2.3 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EKE39693.1 - 0.007 15.9 0.1 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Nuc_sug_transp PF04142.10 EKE39695.1 - 6.5e-54 182.6 22.1 8.3e-54 182.2 10.8 2.1 1 1 1 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 EKE39695.1 - 3.5e-06 27.0 29.7 0.00074 19.5 8.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EKE39695.1 - 0.00022 20.8 28.5 0.036 13.7 5.7 3.2 2 2 1 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EKE39695.1 - 0.0029 17.7 22.7 0.013 15.6 5.3 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter DUF4079 PF13301.1 EKE39695.1 - 2.6 8.0 13.5 0.23 11.4 4.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Rap_GAP PF02145.10 EKE39696.1 - 7.5e-51 172.1 0.0 1.6e-50 171.1 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Sulfotransfer_3 PF13469.1 EKE39697.1 - 1.2e-10 42.5 0.0 4.4e-10 40.6 0.0 2.0 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE39697.1 - 0.00062 19.1 0.1 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 Sulfotransferase domain Methyltransf_11 PF08241.7 EKE39698.1 - 6.6e-13 48.9 0.0 2.6e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE39698.1 - 4.9e-06 26.3 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKE39698.1 - 0.0037 17.5 0.2 0.56 10.6 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE39698.1 - 0.0047 17.4 0.9 0.034 14.7 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Bac_GDH PF05088.7 EKE39698.1 - 0.039 11.3 12.5 0.052 10.9 8.6 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Methyltransf_12 PF08242.7 EKE39698.1 - 0.12 12.9 0.0 0.12 12.9 0.0 3.2 2 1 1 3 3 3 0 Methyltransferase domain GPI2 PF06432.6 EKE39699.1 - 2.1e-48 165.1 16.1 2.7e-48 164.7 11.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PUF PF00806.14 EKE39700.1 - 9.8e-28 94.0 3.7 5.3e-08 31.9 0.0 4.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat LcrV PF04792.7 EKE39700.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein Smr PF01713.16 EKE39701.1 - 6e-06 26.3 1.1 1.1e-05 25.4 0.1 1.9 2 0 0 2 2 2 1 Smr domain B5 PF03484.10 EKE39701.1 - 0.073 12.9 0.1 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetase B5 domain Lamp PF01299.12 EKE39701.1 - 2.1 7.4 8.8 3.4 6.7 6.1 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Alkyl_sulf_dimr PF14863.1 EKE39703.1 - 3.4e-59 199.1 0.1 5.6e-59 198.4 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 EKE39703.1 - 4.5e-27 94.5 0.0 1.1e-26 93.2 0.0 1.7 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 EKE39703.1 - 2.6e-19 69.6 0.2 1.2e-15 57.6 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE39703.1 - 1.9e-06 27.5 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_11 PF13414.1 EKE39703.1 - 1.3e-05 24.7 0.4 3.9e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EKE39703.1 - 0.0013 19.3 0.2 0.0026 18.3 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat SCP2 PF02036.12 EKE39703.1 - 0.0032 17.7 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family TPR_19 PF14559.1 EKE39703.1 - 0.04 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EKE39703.1 - 0.073 13.2 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 FDF PF09532.5 EKE39704.1 - 3.4 8.2 10.6 12 6.5 7.3 2.1 1 1 0 1 1 1 0 FDF domain CBM_20 PF00686.14 EKE39705.1 - 8.4e-11 41.3 0.0 1.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain UCR_hinge PF02320.11 EKE39705.1 - 0.046 13.6 0.6 4.8 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein SNARE PF05739.14 EKE39706.1 - 4.5e-09 35.8 1.9 4.5e-09 35.8 1.3 2.3 3 0 0 3 3 3 1 SNARE domain NPV_P10 PF05531.7 EKE39706.1 - 2e-05 24.7 9.2 0.0021 18.2 3.1 3.4 2 2 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.15 EKE39706.1 - 0.00014 21.0 2.6 0.00014 21.0 1.8 2.4 2 1 0 2 2 1 1 Tropomyosin V-SNARE_C PF12352.3 EKE39706.1 - 0.027 14.5 0.0 0.092 12.8 0.0 2.0 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus UPF0184 PF03670.8 EKE39706.1 - 0.034 14.3 1.0 0.14 12.3 0.2 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) PLAC9 PF15205.1 EKE39706.1 - 0.13 12.6 1.2 0.63 10.3 0.2 2.4 2 1 0 2 2 2 0 Placenta-specific protein 9 DUF848 PF05852.6 EKE39706.1 - 0.14 12.0 11.0 0.05 13.4 1.1 3.2 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Reo_sigmaC PF04582.7 EKE39706.1 - 0.15 11.1 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Serine_rich PF08824.5 EKE39706.1 - 0.22 11.2 5.9 3.2 7.4 0.7 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain KH_5 PF13184.1 EKE39706.1 - 0.3 10.9 8.8 0.51 10.1 2.4 2.6 2 0 0 2 2 2 0 NusA-like KH domain Synaptobrevin PF00957.16 EKE39706.1 - 0.62 9.7 7.7 4.5 6.9 5.4 2.4 1 1 0 1 1 1 0 Synaptobrevin Syntaxin PF00804.20 EKE39706.1 - 1.1 9.4 19.1 0.077 13.1 0.6 3.3 2 1 1 3 3 3 0 Syntaxin Laminin_II PF06009.7 EKE39706.1 - 7 6.4 10.5 0.33 10.6 0.7 2.7 2 1 1 3 3 3 0 Laminin Domain II Fib_alpha PF08702.5 EKE39706.1 - 8.5 6.4 9.4 7 6.7 0.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family WASH-7_mid PF14744.1 EKE39707.1 - 8.7e-110 366.8 15.7 8.7e-110 366.8 10.9 2.2 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_C PF14746.1 EKE39707.1 - 7.9e-30 103.6 3.8 7.9e-30 103.6 2.7 2.4 2 0 0 2 2 2 1 WASH complex subunit 7, C-terminal zf-LYAR PF08790.6 EKE39708.1 - 5.4e-08 32.3 6.0 5.4e-08 32.3 4.2 2.9 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger CDC27 PF09507.5 EKE39708.1 - 0.38 9.9 77.4 0.6 9.2 53.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2 PF00096.21 EKE39708.1 - 0.52 10.7 9.1 3.1 8.3 2.0 2.7 1 1 1 2 2 2 0 Zinc finger, C2H2 type Aa_trans PF01490.13 EKE39709.1 - 1.3e-17 63.4 36.2 2e-17 62.7 25.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EKE39709.1 - 2.4e-09 36.2 43.6 2.4e-09 36.2 30.2 2.0 2 0 0 2 2 2 1 Amino acid permease DUF3687 PF12459.3 EKE39709.1 - 0.14 11.3 6.1 0.72 9.1 0.3 2.6 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein Rcd1 PF04078.8 EKE39710.1 - 3.8e-63 212.7 3.9 4.8e-63 212.4 2.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rrn6 PF10214.4 EKE39710.1 - 0.93 7.5 4.2 1.5 6.7 2.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ras PF00071.17 EKE39711.1 - 1.5e-48 164.2 0.1 1.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39711.1 - 6.9e-17 62.0 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39711.1 - 7.6e-11 41.5 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39711.1 - 0.00028 20.3 1.6 0.015 14.6 1.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE39711.1 - 0.0029 16.8 0.2 0.0076 15.4 0.0 1.7 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE39711.1 - 0.0049 16.8 0.0 0.0082 16.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EKE39711.1 - 0.013 15.0 0.4 4.6 6.7 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2305 PF10230.4 EKE39712.1 - 3e-34 118.6 0.6 3.5e-34 118.4 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EKE39712.1 - 5.4e-08 33.0 0.0 6.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE39712.1 - 0.0019 17.8 0.0 0.0085 15.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKE39712.1 - 0.0023 17.6 0.0 0.0038 17.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Oxidored_q1_C PF01010.14 EKE39712.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Maf PF02545.9 EKE39713.1 - 5.9e-49 165.8 0.0 7.1e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF3993 PF13158.1 EKE39713.1 - 0.0031 17.3 0.3 0.84 9.4 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3993) COOH-NH2_lig PF14395.1 EKE39713.1 - 0.06 12.4 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Rad4 PF03835.10 EKE39713.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Phosphorylase PF00343.15 EKE39715.1 - 4.4e-06 24.8 0.1 6.1e-06 24.4 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate phosphorylase Utp14 PF04615.8 EKE39716.1 - 1.9e-90 304.1 105.4 2.5e-90 303.7 73.0 1.0 1 0 0 1 1 1 1 Utp14 protein EXS PF03124.9 EKE39717.1 - 1e-65 222.0 29.5 1.6e-65 221.4 20.4 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EKE39717.1 - 1.2e-27 97.4 13.8 2.6e-27 96.3 9.5 1.6 1 1 0 1 1 1 1 SPX domain Rer1 PF03248.8 EKE39719.1 - 4.8e-49 166.3 16.9 9.7e-49 165.3 11.7 1.4 1 1 0 1 1 1 1 Rer1 family Oxidored_q3 PF00499.15 EKE39719.1 - 0.042 13.6 9.4 0.075 12.8 6.5 1.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2208 PF09973.4 EKE39719.1 - 0.11 11.7 7.9 0.13 11.4 0.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Peptidase_M3 PF01432.15 EKE39719.1 - 0.15 11.0 1.1 0.19 10.7 0.8 1.1 1 0 0 1 1 1 0 Peptidase family M3 AmiS_UreI PF02293.10 EKE39720.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 AmiS/UreI family transporter Peptidase_C1 PF00112.18 EKE39721.1 - 3.7e-59 200.2 0.5 5.2e-59 199.7 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE39721.1 - 1e-12 48.1 1.0 3.1e-12 46.5 0.7 1.9 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) His_Phos_1 PF00300.17 EKE39723.1 - 7e-31 107.4 0.0 2.1e-30 105.8 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) MucB_RseB PF03888.9 EKE39724.1 - 0.041 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB family PH PF00169.24 EKE39724.1 - 0.23 11.6 5.3 0.51 10.5 3.6 1.9 1 1 0 1 1 1 0 PH domain Ras PF00071.17 EKE39725.1 - 7.6e-51 171.7 1.3 8.7e-51 171.5 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39725.1 - 1.9e-19 70.3 0.1 2.8e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39725.1 - 9.7e-14 50.9 0.1 1.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39725.1 - 1.6e-06 27.6 0.5 2.6e-06 27.0 0.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE39725.1 - 7.5e-05 22.0 0.2 0.0065 15.6 0.1 2.0 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE39725.1 - 7.8e-05 22.6 0.3 0.00018 21.4 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE39725.1 - 0.0016 17.7 0.4 0.0075 15.5 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EKE39725.1 - 0.025 14.0 0.3 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PqqD PF05402.7 EKE39726.1 - 0.03 14.3 0.0 10 6.2 0.0 3.6 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Ribonuclease_T2 PF00445.13 EKE39727.1 - 1.9e-17 63.5 1.7 2.5e-17 63.1 1.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4355 PF14265.1 EKE39728.1 - 0.011 15.7 16.8 0.016 15.1 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) FlaC_arch PF05377.6 EKE39728.1 - 0.028 14.3 4.0 0.54 10.1 1.1 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YvrJ PF12841.2 EKE39728.1 - 0.13 11.6 0.9 0.29 10.4 0.6 1.6 1 0 0 1 1 1 0 YvrJ protein family Tom22 PF04281.8 EKE39728.1 - 2.3 7.7 10.0 3.8 7.0 6.9 1.5 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4407 PF14362.1 EKE39728.1 - 3.1 6.6 14.1 11 4.9 9.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 EKE39728.1 - 5.3 7.1 15.3 1.2e+02 2.7 10.6 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YjgP_YjgQ PF03739.9 EKE39728.1 - 5.7 5.5 8.2 48 2.5 5.7 1.9 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4094 PF13334.1 EKE39728.1 - 8.7 6.8 9.0 3e+02 1.8 6.3 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) IncFII_repA PF02387.10 EKE39728.1 - 9.3 5.3 14.2 15 4.6 9.8 1.3 1 1 0 1 1 1 0 IncFII RepA protein family Peptidase_C1 PF00112.18 EKE39729.1 - 0.0054 16.6 1.0 0.014 15.2 0.5 1.8 2 0 0 2 2 2 1 Papain family cysteine protease Sep15_SelM PF08806.6 EKE39730.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.5 1 1 0 1 1 1 1 Sep15/SelM redox domain Pkinase PF00069.20 EKE39731.1 - 1.4e-46 158.7 0.0 3.4e-46 157.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39731.1 - 6.7e-45 153.1 0.0 1.1e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3112 PF11309.3 EKE39734.1 - 0.084 12.6 2.4 0.16 11.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) TLD PF07534.11 EKE39735.1 - 2.3e-05 24.4 1.2 7e-05 22.8 0.5 1.9 2 0 0 2 2 2 1 TLD Viral_env_E26 PF11050.3 EKE39735.1 - 0.057 12.6 0.1 0.092 11.9 0.1 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 F-box-like PF12937.2 EKE39736.1 - 8.7e-11 41.3 1.5 2.2e-10 40.1 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKE39736.1 - 2e-08 33.6 2.2 4.4e-08 32.5 1.5 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EKE39736.1 - 0.12 12.3 2.6 0.77 9.7 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat PNTB PF02233.11 EKE39737.1 - 1.4e-79 268.0 5.6 1.6e-79 267.8 3.9 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.17 EKE39737.1 - 0.094 12.4 0.2 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DUF333 PF03891.10 EKE39738.1 - 0.023 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF333) U5_2-snRNA_bdg PF10597.4 EKE39738.1 - 0.8 9.3 7.3 0.13 11.8 1.5 2.2 2 1 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 RhoGEF PF00621.15 EKE39739.1 - 9.5e-42 142.9 4.0 9.5e-42 142.9 2.7 2.1 1 1 2 3 3 3 1 RhoGEF domain FYVE PF01363.16 EKE39739.1 - 3.8e-20 71.5 9.8 7.5e-20 70.6 6.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE39739.1 - 3.2e-09 36.9 0.1 6.2e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 EKE39739.1 - 0.00047 20.0 4.7 0.00047 20.0 3.3 2.4 3 0 0 3 3 3 1 FYVE-type zinc finger DUF3106 PF11304.3 EKE39739.1 - 0.11 12.9 0.0 5.9 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Mcp5_PH PF12814.2 EKE39739.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 EKE39739.1 - 0.34 11.1 2.9 3.1 8.0 0.4 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain HypA PF01155.14 EKE39739.1 - 4.6 6.9 10.3 2.9 7.6 3.7 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ras PF00071.17 EKE39741.1 - 3.7e-56 188.9 0.9 4.2e-56 188.7 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39741.1 - 2.9e-19 69.6 0.0 4.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39741.1 - 4.6e-12 45.5 0.3 6e-12 45.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39741.1 - 1.6e-07 30.9 0.3 1.8e-06 27.5 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE39741.1 - 0.00021 20.5 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE39741.1 - 0.0016 18.4 0.1 0.0023 17.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE39741.1 - 0.0022 17.2 0.0 0.0046 16.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EKE39741.1 - 0.0027 16.8 0.3 0.0038 16.3 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3398 PF11878.3 EKE39741.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) AAA_14 PF13173.1 EKE39741.1 - 0.068 13.0 0.1 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EKE39741.1 - 0.076 12.4 0.4 0.26 10.7 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF4097 PF13349.1 EKE39742.1 - 0.0069 15.9 0.7 0.019 14.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4097) RhoGAP PF00620.22 EKE39744.1 - 8.2e-23 80.7 0.3 1.9e-22 79.5 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EKE39744.1 - 0.018 15.2 0.1 0.018 15.2 0.0 2.5 3 1 0 3 3 3 0 PH domain Brix PF04427.13 EKE39746.1 - 6.7e-27 94.3 1.2 1e-26 93.7 0.8 1.2 1 0 0 1 1 1 1 Brix domain DUF737 PF05300.6 EKE39747.1 - 0.1 12.5 3.0 0.14 12.1 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF737) Rab5ip PF07019.7 EKE39748.1 - 3.6e-13 49.4 7.4 4.4e-13 49.1 5.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF4199 PF13858.1 EKE39748.1 - 0.34 10.8 6.2 0.52 10.2 4.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3021 PF11457.3 EKE39748.1 - 0.6 9.9 6.7 0.21 11.4 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) RhoGAP PF00620.22 EKE39749.1 - 7.9e-17 61.2 0.0 2e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain TA0956 PF11513.3 EKE39749.1 - 0.0095 15.9 4.7 6.4 6.8 1.0 3.5 2 1 1 3 3 3 2 Thermoplasma acidophilum protein TA0956 HEAT_2 PF13646.1 EKE39750.1 - 1.3e-09 38.2 0.0 0.0069 16.6 0.0 4.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EKE39750.1 - 1.5e-06 27.7 7.2 0.067 13.3 0.0 7.6 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 EKE39750.1 - 0.00029 21.2 0.8 15 6.2 0.0 5.6 4 2 1 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EKE39750.1 - 0.0027 17.5 0.3 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Ipi1_N PF12333.3 EKE39750.1 - 0.016 15.1 0.3 4.7 7.2 0.1 3.9 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Spatacsin_C PF14649.1 EKE39751.1 - 3.8e-14 52.2 9.2 1.7e-13 50.1 6.4 2.2 1 1 0 1 1 1 1 Spatacsin C-terminus RabGAP-TBC PF00566.13 EKE39752.1 - 2.2e-42 144.9 8.6 2.9e-42 144.5 6.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cullin_binding PF03556.10 EKE39752.1 - 2.5 8.2 6.2 0.48 10.5 0.5 2.3 3 0 0 3 3 3 0 Cullin binding RhoGEF PF00621.15 EKE39753.1 - 2.7e-32 112.1 0.0 4.4e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EKE39753.1 - 2.8e-10 39.9 8.9 2.8e-10 39.9 6.2 2.6 2 1 0 2 2 2 1 FYVE zinc finger PH PF00169.24 EKE39753.1 - 3.1e-07 30.5 0.1 7.6e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 EKE39753.1 - 0.0016 18.3 4.2 0.0076 16.1 2.9 2.3 1 0 0 1 1 1 1 FYVE-type zinc finger C1_3 PF07649.7 EKE39753.1 - 1.6 8.8 18.3 0.69 10.0 9.7 2.5 2 0 0 2 2 2 0 C1-like domain Thioredoxin PF00085.15 EKE39754.1 - 4e-29 100.3 0.1 4.6e-29 100.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE39754.1 - 4.9e-10 39.6 0.2 1.6e-09 37.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKE39754.1 - 1.3e-07 31.6 0.0 3.8e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EKE39754.1 - 2e-07 30.9 0.1 3.5e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EKE39754.1 - 9.4e-07 28.8 0.2 1.4e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EKE39754.1 - 1.5e-05 24.7 0.2 1.9e-05 24.3 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKE39754.1 - 2e-05 24.2 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_4 PF13462.1 EKE39754.1 - 9.3e-05 22.4 0.1 0.12 12.4 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 EKE39754.1 - 0.00016 21.4 0.1 0.00027 20.6 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EKE39754.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DDE_Tnp_1_2 PF13586.1 EKE39754.1 - 0.055 13.6 0.0 9.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain PdxJ PF03740.8 EKE39755.1 - 0.0048 16.0 1.7 0.0058 15.8 1.2 1.2 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ GLE1 PF07817.8 EKE39755.1 - 0.0074 15.2 12.9 0.25 10.2 3.9 2.0 1 1 1 2 2 2 2 GLE1-like protein RraB PF06877.6 EKE39755.1 - 0.11 13.1 4.0 0.23 12.1 2.8 1.5 1 1 0 1 1 1 0 Regulator of ribonuclease activity B DUF1054 PF06335.7 EKE39755.1 - 0.18 11.4 3.3 0.21 11.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Complex1_LYR_2 PF13233.1 EKE39755.1 - 0.2 12.1 4.2 0.27 11.7 2.8 1.4 1 1 0 1 1 1 0 Complex1_LYR-like AAA_13 PF13166.1 EKE39755.1 - 0.21 10.0 15.7 0.22 9.9 10.9 1.0 1 0 0 1 1 1 0 AAA domain DUF1423 PF07227.6 EKE39755.1 - 0.23 10.0 7.8 0.26 9.8 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) RNB PF00773.14 EKE39755.1 - 0.28 10.4 7.8 0.32 10.2 5.4 1.1 1 0 0 1 1 1 0 RNB domain V_ATPase_I PF01496.14 EKE39755.1 - 0.32 8.7 7.9 0.36 8.6 5.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LUC7 PF03194.10 EKE39755.1 - 0.36 10.3 9.2 0.46 9.9 6.4 1.1 1 0 0 1 1 1 0 LUC7 N_terminus GrpE PF01025.14 EKE39755.1 - 0.37 10.3 8.3 0.45 10.0 5.7 1.2 1 0 0 1 1 1 0 GrpE OmpH PF03938.9 EKE39755.1 - 0.44 10.4 9.8 0.55 10.1 6.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AcetylCoA_hyd_C PF13336.1 EKE39755.1 - 0.67 9.6 4.3 3.8 7.1 0.6 2.1 1 1 1 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Dna2 PF08696.6 EKE39755.1 - 0.7 9.1 7.5 0.83 8.9 5.2 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF342 PF03961.8 EKE39755.1 - 0.98 7.7 12.6 1.1 7.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prominin PF05478.6 EKE39755.1 - 1.1 6.6 10.3 1.4 6.3 7.1 1.0 1 0 0 1 1 1 0 Prominin DNA_Packaging PF11053.3 EKE39755.1 - 1.2 8.7 8.3 1e+02 2.4 5.8 2.5 1 1 0 1 1 1 0 Terminase DNA packaging enzyme MRP-63 PF14978.1 EKE39755.1 - 1.5 9.2 6.7 3.2 8.2 4.5 1.6 1 1 0 1 1 1 0 Mitochondrial ribosome protein 63 Allexi_40kDa PF05549.6 EKE39755.1 - 1.7 7.8 6.6 2 7.6 4.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein RP-C_C PF11800.3 EKE39755.1 - 1.9 8.1 6.5 2.1 8.0 4.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region TMPIT PF07851.8 EKE39755.1 - 2.6 7.0 7.7 3.1 6.7 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein ARD PF03079.9 EKE39755.1 - 5.4 6.9 7.4 6.6 6.6 4.8 1.4 1 1 0 1 1 1 0 ARD/ARD' family RasGEF_N PF00618.15 EKE39755.1 - 8.5 6.5 8.3 17 5.5 5.8 1.6 1 1 0 1 1 1 0 RasGEF N-terminal motif Syja_N PF02383.13 EKE39756.1 - 4.9e-61 206.2 2.7 9.7e-61 205.2 1.8 1.4 1 0 0 1 1 1 1 SacI homology domain TcdA_TcdB PF12919.2 EKE39757.1 - 0.093 11.2 5.7 0.1 11.0 4.0 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF3687 PF12459.3 EKE39757.1 - 0.1 11.8 3.9 0.18 11.0 2.7 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein UCH PF00443.24 EKE39758.1 - 2.8e-54 184.0 7.6 2.8e-54 184.0 5.3 2.6 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE39758.1 - 2.6e-23 82.8 2.0 2.6e-23 82.8 1.4 2.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Lactamase_B PF00753.22 EKE39761.1 - 1.1e-16 61.0 0.1 1.3e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE39761.1 - 9.6e-14 51.3 0.1 5.4e-12 45.6 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta-Casp PF10996.3 EKE39761.1 - 2.2e-06 27.6 0.0 6.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EKE39761.1 - 5.5e-05 22.9 0.1 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Foamy_virus_ENV PF03408.9 EKE39761.1 - 0.026 12.1 0.2 0.036 11.5 0.1 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Lactamase_B_3 PF13483.1 EKE39761.1 - 0.095 12.4 0.0 0.35 10.5 0.0 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ArfGap PF01412.13 EKE39762.1 - 5.2e-33 113.2 0.6 5.2e-33 113.2 0.4 2.5 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_5 PF13857.1 EKE39762.1 - 1.9e-10 40.6 0.1 1.3e-05 25.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE39762.1 - 1.1e-06 28.8 0.2 2.9e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKE39762.1 - 4.2e-05 23.9 0.1 0.00023 21.5 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EKE39762.1 - 0.061 13.1 0.0 2.6 8.0 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat YlbD_coat PF14071.1 EKE39762.1 - 0.42 10.6 0.1 0.42 10.6 0.1 3.1 2 1 1 3 3 3 0 Putative coat protein SH2 PF00017.19 EKE39764.1 - 6.6e-09 35.4 0.0 2e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Pkinase_Tyr PF07714.12 EKE39764.1 - 0.0019 17.3 1.0 0.0031 16.6 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39764.1 - 0.0021 17.2 0.1 0.01 15.0 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain DUF2430 PF10353.4 EKE39764.1 - 0.0055 16.8 2.6 0.013 15.7 0.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2430) Kinase-like PF14531.1 EKE39764.1 - 0.055 12.4 0.2 0.13 11.2 0.1 1.5 1 1 0 1 1 1 0 Kinase-like zf-C3HC4_2 PF13923.1 EKE39765.1 - 0.027 14.5 5.8 0.23 11.5 4.5 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE39765.1 - 0.072 12.7 5.9 0.12 12.0 4.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE39765.1 - 0.42 10.4 7.5 0.7 9.7 5.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-H2C2_2 PF13465.1 EKE39765.1 - 7.3 7.0 6.7 0.91 9.9 0.9 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Arm PF00514.18 EKE39766.1 - 1.3e-05 24.8 0.1 0.055 13.3 0.0 4.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3452 PF11934.3 EKE39766.1 - 0.3 10.4 2.4 7.3 5.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) C2 PF00168.25 EKE39767.1 - 7.6e-19 67.3 0.0 2.3e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 C2 domain CEP76-C2 PF15627.1 EKE39767.1 - 0.012 15.0 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain WD40 PF00400.27 EKE39768.1 - 2.3e-50 166.7 21.2 5.6e-12 45.0 0.3 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 EKE39768.1 - 5.9e-10 38.2 4.1 9.8e-10 37.5 2.8 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EKE39768.1 - 1.2e-06 28.4 0.1 0.046 13.4 0.0 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EKE39768.1 - 3.2e-05 22.2 2.7 0.66 8.0 0.0 4.0 2 2 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EKE39768.1 - 0.001 18.6 0.1 0.13 11.7 0.0 2.2 1 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EKE39768.1 - 0.0047 15.7 0.6 2 7.0 0.1 3.1 1 1 1 2 2 2 1 Nup133 N terminal like DUF3312 PF11768.3 EKE39768.1 - 0.017 13.3 0.0 0.12 10.5 0.0 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 EKE39768.1 - 0.026 12.3 3.3 1.7 6.3 2.2 2.3 1 1 0 1 1 1 0 IKI3 family PAC2 PF09754.4 EKE39769.1 - 5.3e-19 68.9 0.0 1.8e-16 60.6 0.0 2.0 1 1 1 2 2 2 2 PAC2 family IF4E PF01652.13 EKE39770.1 - 9.3e-25 87.0 0.0 1.1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CitT PF12431.3 EKE39770.1 - 0.04 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator Ras PF00071.17 EKE39771.1 - 7.5e-61 204.2 0.6 1.1e-60 203.7 0.4 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39771.1 - 3.9e-18 66.0 0.0 7.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39771.1 - 4.6e-15 55.2 0.0 6.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE39771.1 - 6.3e-07 29.3 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE39771.1 - 8.5e-06 25.3 0.1 2.2e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EKE39771.1 - 0.00014 22.0 0.1 0.00037 20.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.1 EKE39771.1 - 0.00037 19.6 0.5 0.00061 18.9 0.3 1.3 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EKE39771.1 - 0.0044 16.1 0.1 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EKE39771.1 - 0.0091 15.1 0.0 0.024 13.8 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKE39771.1 - 0.011 16.0 0.2 0.02 15.2 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EKE39771.1 - 0.016 15.1 0.1 0.05 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKE39771.1 - 0.077 12.6 0.3 0.13 11.9 0.2 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_21 PF13304.1 EKE39771.1 - 0.11 12.4 2.7 0.36 10.7 1.9 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKE39771.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EKE39771.1 - 0.14 11.9 0.1 0.7 9.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TLD PF07534.11 EKE39772.1 - 3.2e-05 23.9 0.2 6e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 TLD HHH_2 PF12826.2 EKE39772.1 - 0.024 14.5 0.5 4.5 7.2 0.3 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif FlaG PF03646.10 EKE39772.1 - 0.055 13.6 7.9 0.03 14.4 3.6 2.0 2 0 0 2 2 2 0 FlaG protein PRP1_N PF06424.7 EKE39772.1 - 0.17 12.2 1.8 0.34 11.2 1.2 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal AAA_11 PF13086.1 EKE39772.1 - 0.2 11.2 2.9 0.31 10.5 2.0 1.3 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EKE39773.1 - 3.4e-27 94.8 0.3 4.1e-27 94.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39773.1 - 1.8e-11 44.5 0.0 3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE39773.1 - 3.1e-08 33.2 0.6 5.2e-08 32.5 0.3 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39773.1 - 1.2e-05 25.2 0.1 1.9e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EKE39773.1 - 1.2e-05 24.6 0.1 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39773.1 - 0.00047 19.3 0.8 0.001 18.2 0.6 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ArgK PF03308.11 EKE39773.1 - 0.004 15.9 0.5 0.2 10.3 0.1 2.1 2 0 0 2 2 2 2 ArgK protein NTPase_1 PF03266.10 EKE39773.1 - 0.04 13.6 0.0 0.094 12.4 0.0 1.6 1 1 1 2 2 2 0 NTPase cobW PF02492.14 EKE39773.1 - 0.099 12.0 0.6 12 5.3 0.1 2.6 1 1 2 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EKE39773.1 - 0.1 11.7 0.1 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Got1 PF04178.7 EKE39774.1 - 1e-09 38.4 26.7 1.7e-09 37.7 18.1 1.6 1 1 1 2 2 2 1 Got1/Sft2-like family NfeD PF01957.13 EKE39774.1 - 7.1 6.7 7.6 5.2 7.2 4.1 1.7 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Pmp3 PF01679.12 EKE39775.1 - 1e-18 66.7 11.5 1.2e-18 66.5 8.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2198 PF09964.4 EKE39775.1 - 0.14 11.9 2.1 0.15 11.8 1.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF1145 PF06611.7 EKE39775.1 - 2.3 7.9 6.1 0.33 10.6 1.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1145) Prefoldin PF02996.12 EKE39776.1 - 3.4e-23 81.5 1.6 3.8e-23 81.3 1.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit K-box PF01486.12 EKE39776.1 - 0.048 13.4 0.1 0.048 13.4 0.1 1.7 2 0 0 2 2 2 0 K-box region DUF1798 PF08807.5 EKE39777.1 - 0.0033 17.1 0.4 0.007 16.0 0.3 1.5 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) AAA_13 PF13166.1 EKE39778.1 - 0.0011 17.5 13.0 0.0011 17.5 9.0 1.0 1 0 0 1 1 1 1 AAA domain Cytochrom_B562 PF07361.6 EKE39778.1 - 0.022 15.1 1.6 0.022 15.1 1.1 2.0 1 1 1 2 2 2 0 Cytochrome b562 Lyase_8_N PF08124.6 EKE39778.1 - 0.033 13.0 3.3 0.04 12.7 2.3 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Strep_SA_rep PF06696.6 EKE39778.1 - 0.04 13.6 0.4 0.04 13.6 0.3 2.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Mnd1 PF03962.10 EKE39778.1 - 0.05 13.2 12.7 0.058 13.0 8.8 1.1 1 0 0 1 1 1 0 Mnd1 family Baculo_PEP_C PF04513.7 EKE39778.1 - 0.055 13.3 0.5 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EKE39778.1 - 0.065 13.0 4.8 0.93 9.4 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IFT46_B_C PF12317.3 EKE39778.1 - 0.071 12.4 6.6 0.58 9.4 1.5 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF1993 PF09351.5 EKE39778.1 - 0.093 12.6 0.9 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Hormone_1 PF00103.15 EKE39778.1 - 0.094 12.0 9.4 0.3 10.4 1.5 2.0 1 1 1 2 2 2 0 Somatotropin hormone family BRICHOS PF04089.9 EKE39778.1 - 0.1 12.4 0.6 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 BRICHOS domain Urocanase PF01175.13 EKE39778.1 - 0.11 10.4 0.4 0.13 10.2 0.3 1.0 1 0 0 1 1 1 0 Urocanase Wax2_C PF12076.3 EKE39778.1 - 0.16 11.7 3.9 5.3 6.7 0.1 2.0 2 0 0 2 2 2 0 WAX2 C-terminal domain NAAA-beta PF15508.1 EKE39778.1 - 0.19 12.1 1.6 0.62 10.4 0.4 2.1 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1574 PF07611.6 EKE39778.1 - 0.25 10.1 5.5 0.3 9.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) SpoU_sub_bind PF08032.7 EKE39778.1 - 0.26 11.4 6.3 1.2 9.3 1.9 2.6 1 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding GvpL_GvpF PF06386.6 EKE39778.1 - 0.33 10.5 4.3 0.41 10.2 3.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HCMV_UL139 PF12507.3 EKE39778.1 - 0.8 9.8 6.3 0.81 9.8 3.7 1.6 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein DUF3573 PF12097.3 EKE39778.1 - 0.82 8.2 4.2 0.93 8.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SlyX PF04102.7 EKE39778.1 - 0.88 9.9 8.1 2.2 8.7 3.7 2.3 1 1 1 2 2 2 0 SlyX IncA PF04156.9 EKE39778.1 - 1.1 8.8 18.4 1.7 8.1 5.1 2.0 1 1 1 2 2 2 0 IncA protein DUF4404 PF14357.1 EKE39778.1 - 2.2 8.7 8.0 2.3 8.6 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) APG6 PF04111.7 EKE39778.1 - 2.8 6.8 13.5 3.6 6.5 9.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 LAGLIDADG_WhiA PF14527.1 EKE39778.1 - 3.7 7.5 6.1 3.5 7.5 1.3 2.2 1 1 1 2 2 2 0 WhiA LAGLIDADG-like domain TPR_MLP1_2 PF07926.7 EKE39778.1 - 4.1 7.1 17.3 13 5.5 12.0 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3007 PF11460.3 EKE39778.1 - 5.4 7.1 6.6 32 4.6 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3007) CorA PF01544.13 EKE39778.1 - 5.7 5.8 9.1 4.1 6.3 1.1 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TMPIT PF07851.8 EKE39778.1 - 7.2 5.5 13.5 6.7 5.6 8.3 1.6 1 1 1 2 2 2 0 TMPIT-like protein Syntaxin PF00804.20 EKE39778.1 - 8.4 6.6 15.6 15 5.7 7.1 2.4 1 1 2 3 3 3 0 Syntaxin CLASP_N PF12348.3 EKE39779.1 - 0.013 14.8 14.0 1.6 8.0 0.4 4.2 3 1 0 3 3 3 0 CLASP N terminal DUF2435 PF10363.4 EKE39779.1 - 8.1 6.4 8.7 13 5.8 0.1 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF2435) Rogdi_lz PF10259.4 EKE39780.1 - 1.9e-10 40.3 0.3 2.5e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DSHCT PF08148.7 EKE39781.1 - 1.8e-38 131.5 0.6 5.9e-38 129.8 0.4 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EKE39781.1 - 1e-17 64.1 0.2 1e-17 64.1 0.1 2.7 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE39781.1 - 3.3e-05 23.6 0.0 0.0002 21.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE39781.1 - 0.0018 18.1 3.1 0.0018 18.1 2.1 3.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Mon1 PF03164.9 EKE39782.1 - 5.7e-19 68.0 0.0 8.2e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 Rsbr_N PF08678.5 EKE39782.1 - 0.11 12.3 0.1 0.11 12.3 0.0 2.6 4 0 0 4 4 4 0 Rsbr N terminal Lipoprotein_7 PF01540.11 EKE39783.1 - 0.035 13.1 13.9 0.13 11.2 1.6 2.4 1 1 1 2 2 2 0 Adhesin lipoprotein HCMV_UL139 PF12507.3 EKE39783.1 - 0.53 10.4 5.2 0.14 12.3 1.2 1.8 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein MRP-L47 PF06984.8 EKE39783.1 - 5.9 6.8 7.9 1.1 9.2 0.6 2.7 2 1 0 3 3 3 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) UCH PF00443.24 EKE39784.1 - 3.9e-66 222.9 25.5 5.1e-64 215.9 15.8 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE39784.1 - 3.1e-21 76.0 12.8 7.2e-17 61.7 4.7 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Memo PF01875.12 EKE39785.1 - 5.3e-41 140.3 0.0 6e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein NAD_binding_10 PF13460.1 EKE39785.1 - 0.13 12.2 0.1 0.47 10.4 0.0 1.7 1 1 0 2 2 2 0 NADH(P)-binding WD40 PF00400.27 EKE39786.1 - 0.0046 16.7 4.5 0.2 11.6 0.5 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CTP_transf_1 PF01148.15 EKE39787.1 - 1.1e-10 41.6 14.7 1.7e-10 41.0 10.2 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Proteasome PF00227.21 EKE39789.1 - 1.2e-39 135.6 2.4 1.4e-39 135.3 1.7 1.0 1 0 0 1 1 1 1 Proteasome subunit HEAT_2 PF13646.1 EKE39790.1 - 9.4e-08 32.2 0.0 0.0045 17.2 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats Cnd3 PF12719.2 EKE39790.1 - 9.8e-07 28.0 1.3 9.8e-07 28.0 0.9 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EKE39790.1 - 8.9e-06 25.3 0.0 0.66 10.2 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 EKE39790.1 - 0.00037 19.9 5.8 0.044 13.1 0.2 3.2 2 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EKE39790.1 - 0.00088 19.6 0.6 0.96 10.0 0.0 4.2 4 1 0 4 4 4 1 HEAT-like repeat DUF4120 PF13496.1 EKE39790.1 - 0.011 15.6 0.1 0.042 13.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) SHS2_FTSA PF02491.15 EKE39790.1 - 0.031 14.1 0.1 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA Vac14_Fab1_bd PF12755.2 EKE39790.1 - 0.11 12.8 2.5 23 5.4 0.0 4.3 3 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF3677 PF12432.3 EKE39790.1 - 0.12 12.8 5.0 0.47 10.9 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3677) Y_phosphatase PF00102.22 EKE39791.1 - 6.7e-55 185.9 1.8 6.4e-49 166.4 0.3 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EKE39791.1 - 0.0041 16.7 0.0 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EKE39791.1 - 0.028 14.6 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKE39791.1 - 0.041 13.9 0.4 0.17 11.9 0.0 2.2 3 0 0 3 3 3 0 Inositol hexakisphosphate TLD PF07534.11 EKE39792.1 - 1.7e-05 24.8 0.2 2.8e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 TLD Phospholip_B PF04916.8 EKE39793.1 - 2.8e-109 365.7 12.3 3.3e-109 365.5 8.5 1.0 1 0 0 1 1 1 1 Phospholipase B Amidohydro_4 PF13147.1 EKE39794.1 - 3.4e-32 112.5 0.0 5.7e-32 111.8 0.0 1.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EKE39794.1 - 2.6e-16 60.2 0.0 4.4e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKE39794.1 - 3.2e-14 52.5 0.6 3.2e-14 52.5 0.4 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EKE39794.1 - 0.00079 18.7 0.0 0.051 12.7 0.0 2.5 3 0 0 3 3 3 1 Amidohydrolase family Sipho_tail PF05709.6 EKE39794.1 - 0.035 13.2 0.0 0.05 12.7 0.0 1.4 1 1 0 1 1 1 0 Phage tail protein Urease_alpha PF00449.15 EKE39794.1 - 0.098 12.7 0.2 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain PAP2 PF01569.16 EKE39795.1 - 5.9e-20 71.2 0.8 1.1e-19 70.4 0.1 1.6 1 1 1 2 2 2 1 PAP2 superfamily BPD_transp_2 PF02653.11 EKE39795.1 - 0.2 10.5 3.6 0.12 11.3 0.3 1.8 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component DUF1673 PF07895.6 EKE39795.1 - 1.1 8.7 5.5 9.8 5.6 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1673) Avl9 PF09794.4 EKE39797.1 - 6.8e-10 37.9 0.1 3.5e-08 32.3 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 Myotub-related PF06602.9 EKE39798.1 - 3.7e-82 275.9 1.4 6.1e-82 275.2 1.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 EKE39798.1 - 1.8e-05 24.2 0.2 6.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EKE39798.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Tetraspannin PF00335.15 EKE39799.1 - 0.01 15.1 32.6 0.016 14.4 22.6 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4293 PF14126.1 EKE39799.1 - 0.28 11.1 12.1 0.042 13.7 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF4064 PF13273.1 EKE39799.1 - 1.4 9.1 28.2 2.4 8.2 12.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) PIRT PF15099.1 EKE39799.1 - 3.2 6.9 18.7 0.43 9.7 7.1 2.5 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2231 PF09990.4 EKE39799.1 - 6.4 7.1 8.2 0.98 9.8 2.4 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) SLX9 PF15341.1 EKE39800.1 - 0.0042 17.5 0.5 0.0075 16.6 0.3 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 BAP PF06639.6 EKE39800.1 - 0.031 13.9 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) Flavi_propep PF01570.12 EKE39800.1 - 0.12 12.1 0.3 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide PXA PF02194.10 EKE39801.1 - 4.6e-05 23.0 0.6 0.032 13.8 0.3 2.3 2 0 0 2 2 2 2 PXA domain GRAM PF02893.15 EKE39801.1 - 0.0011 18.4 0.1 0.0037 16.7 0.1 1.9 1 0 0 1 1 1 1 GRAM domain Aa_trans PF01490.13 EKE39802.1 - 3.7e-23 81.6 33.1 4.9e-23 81.2 22.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EKE39802.1 - 2.4e-05 23.3 11.3 2.4e-05 23.3 7.8 2.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CTDII PF01556.13 EKE39803.1 - 0.017 14.9 0.7 0.69 9.8 0.0 3.2 3 0 0 3 3 3 0 DnaJ C terminal domain Myb_DNA-binding PF00249.26 EKE39804.1 - 1.4e-26 92.2 5.9 3.3e-11 43.0 0.0 5.7 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE39804.1 - 1.6e-17 63.3 13.9 6.7e-08 32.5 0.2 5.8 3 1 2 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EKE39804.1 - 0.043 13.6 0.0 0.91 9.3 0.0 2.8 2 0 0 2 2 2 0 Rap1 Myb domain PX PF00787.19 EKE39805.1 - 1.7e-20 72.8 0.2 2.1e-20 72.5 0.2 1.0 1 0 0 1 1 1 1 PX domain EF-hand_6 PF13405.1 EKE39806.1 - 0.011 15.5 0.4 2.4 8.2 0.0 4.6 5 0 0 5 5 5 0 EF-hand domain Ribosomal_S26e PF01283.14 EKE39807.1 - 1.3e-46 157.4 12.4 1.8e-46 157.0 8.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EKE39807.1 - 0.0018 18.6 1.5 0.15 12.4 0.5 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Mu-like_Com PF10122.4 EKE39807.1 - 0.0096 14.9 0.7 0.02 13.9 0.5 1.6 1 0 0 1 1 1 1 Mu-like prophage protein Com SRP19 PF01922.12 EKE39807.1 - 0.0097 16.4 2.2 0.022 15.3 1.5 1.8 1 1 0 1 1 1 1 SRP19 protein GFA PF04828.9 EKE39807.1 - 0.025 14.5 2.6 0.12 12.3 1.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Fer4 PF00037.22 EKE39807.1 - 0.19 11.3 5.0 1.1 8.9 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 EKE39807.1 - 0.23 11.8 4.2 0.22 11.9 1.7 1.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain zf-ribbon_3 PF13248.1 EKE39807.1 - 0.57 9.4 3.9 3.8 6.8 2.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Fer4_9 PF13187.1 EKE39807.1 - 0.61 10.4 4.6 0.73 10.1 1.8 2.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE39807.1 - 1.6 8.7 4.4 1.2 9.1 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 EKE39807.1 - 7.4 7.0 8.8 5.7 7.4 1.9 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain CAF1 PF04857.15 EKE39808.1 - 2.7e-45 154.7 0.6 1.3e-35 123.0 0.1 2.3 1 1 1 2 2 2 2 CAF1 family ribonuclease SecE PF00584.15 EKE39809.1 - 8.5e-12 44.4 0.0 9.5e-12 44.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TTL PF03133.10 EKE39810.1 - 7.6e-39 133.3 10.6 1.4e-38 132.5 7.4 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MCM PF00493.18 EKE39811.1 - 3.9e-96 321.7 0.0 3.9e-96 321.7 0.0 1.8 2 0 0 2 2 2 1 MCM2/3/5 family AAA_5 PF07728.9 EKE39811.1 - 1.3e-08 34.6 0.0 3.8e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EKE39811.1 - 1.4e-07 30.9 3.6 0.00018 20.7 0.0 3.2 3 1 1 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EKE39811.1 - 0.0077 15.7 0.4 3.8 7.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EKE39811.1 - 0.02 15.0 0.0 0.02 15.0 0.0 3.8 4 2 1 5 5 5 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.5 EKE39811.1 - 0.099 12.6 1.3 0.27 11.2 0.9 1.8 1 0 0 1 1 1 0 Zinc ribbon domain AAA_16 PF13191.1 EKE39811.1 - 0.12 12.3 0.7 0.33 10.9 0.5 1.7 1 0 0 1 1 1 0 AAA ATPase domain ETF_QO PF05187.8 EKE39811.1 - 2.9 7.9 8.6 8 6.5 0.5 2.9 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase MRP-S22 PF10245.4 EKE39812.1 - 0.07 12.5 0.4 0.075 12.4 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 PAP_assoc PF03828.14 EKE39813.1 - 1.7e-08 34.2 0.2 5e-08 32.7 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EKE39813.1 - 1.2e-05 25.4 1.6 1.8e-05 24.9 0.1 2.1 2 1 0 2 2 2 1 Nucleotidyltransferase domain Anp1 PF03452.9 EKE39813.1 - 0.21 10.7 6.5 0.068 12.3 0.8 2.2 2 0 0 2 2 2 0 Anp1 PRKCSH PF07915.8 EKE39814.1 - 7.3e-05 23.4 2.9 0.00015 22.5 2.0 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EKE39814.1 - 0.001 18.5 4.7 0.0034 16.8 3.3 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein ecTbetaR2 PF08917.5 EKE39815.1 - 0.003 17.2 1.1 0.003 17.2 0.8 1.9 2 0 0 2 2 2 1 Transforming growth factor beta receptor 2 ectodomain RabGAP-TBC PF00566.13 EKE39816.1 - 8.4e-31 107.1 14.6 3.2e-29 101.9 10.1 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Galactosyl_T PF01762.16 EKE39817.1 - 3.2e-15 56.2 0.3 5.3e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase FHA PF00498.21 EKE39818.1 - 3.6e-14 52.6 0.1 6.9e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4_4 PF15227.1 EKE39818.1 - 8.4e-07 28.7 14.8 2.2e-06 27.4 10.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EKE39818.1 - 8.5e-06 25.6 13.2 2.5e-05 24.1 9.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE39818.1 - 1.6e-05 24.4 9.3 1.6e-05 24.4 6.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE39818.1 - 1.7e-05 24.4 8.7 3.3e-05 23.4 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE39818.1 - 0.00037 20.1 12.5 0.0016 18.0 8.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKE39818.1 - 0.00046 19.9 12.1 0.00046 19.9 8.4 2.5 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EKE39818.1 - 0.015 15.0 3.5 0.015 15.0 2.4 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EKE39818.1 - 0.47 10.0 5.4 1.3 8.6 3.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LRR_4 PF12799.2 EKE39819.1 - 5.3e-06 25.9 25.6 0.18 11.4 0.0 7.0 5 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE39819.1 - 0.00066 19.3 26.7 0.052 13.3 0.3 6.4 4 3 6 10 10 10 5 Leucine rich repeat LRR_7 PF13504.1 EKE39819.1 - 0.0046 16.9 5.1 83 4.0 0.0 7.2 6 1 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EKE39819.1 - 0.22 11.6 11.0 16 6.0 0.0 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.20 EKE39820.1 - 8.5e-67 225.0 0.0 1.2e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39820.1 - 7.8e-34 116.9 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39820.1 - 1.9e-07 30.3 0.0 4.1e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EKE39820.1 - 3.8e-06 26.1 0.0 7.3e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE39820.1 - 0.0013 18.5 0.0 0.0097 15.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKE39820.1 - 0.06 12.9 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase Prefoldin PF02996.12 EKE39821.1 - 1.7e-06 27.7 1.1 1.7e-06 27.7 0.8 2.3 1 1 0 2 2 2 1 Prefoldin subunit DUF4242 PF14026.1 EKE39821.1 - 0.085 12.9 0.3 0.3 11.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) DUF4145 PF13643.1 EKE39821.1 - 0.13 12.1 1.8 0.29 11.0 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) DNA_pol_alpha_N PF12254.3 EKE39821.1 - 0.13 12.0 2.3 0.62 9.9 1.6 2.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal SieB PF14163.1 EKE39821.1 - 0.15 11.6 2.6 0.19 11.2 1.1 1.7 1 1 0 1 1 1 0 Superinfection exclusion protein B Glypican PF01153.14 EKE39821.1 - 0.43 9.1 6.9 0.096 11.2 2.5 1.5 1 1 0 1 1 1 0 Glypican RasGEF PF00617.14 EKE39825.1 - 3.5e-07 30.1 4.5 2.3e-06 27.4 1.9 2.6 2 0 0 2 2 2 1 RasGEF domain Rubrerythrin PF02915.12 EKE39826.1 - 1.7e-29 102.8 4.0 2.5e-29 102.3 2.8 1.2 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.19 EKE39826.1 - 2.2e-08 33.9 3.1 2.8e-08 33.6 2.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain RNA_POL_M_15KD PF02150.11 EKE39826.1 - 0.0021 17.6 0.0 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit HypA PF01155.14 EKE39826.1 - 0.006 16.2 0.1 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 EKE39826.1 - 0.051 13.2 4.8 0.94 9.2 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DZR PF12773.2 EKE39826.1 - 0.06 13.1 0.3 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF4379 PF14311.1 EKE39826.1 - 0.064 13.0 1.8 0.14 11.9 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4379) FA_desaturase_2 PF03405.9 EKE39826.1 - 0.065 11.9 2.2 0.32 9.7 0.2 2.3 2 1 1 3 3 3 0 Fatty acid desaturase Ferritin_2 PF13668.1 EKE39826.1 - 0.088 12.7 4.4 0.14 12.1 1.2 1.9 1 1 1 2 2 2 0 Ferritin-like domain tRNA-synt_1g PF09334.6 EKE39826.1 - 0.091 11.4 0.6 0.12 10.9 0.1 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (M) Zn-ribbon_8 PF09723.5 EKE39826.1 - 0.42 10.6 4.8 0.64 10.0 2.1 2.2 2 1 0 2 2 2 0 Zinc ribbon domain DUF2383 PF09537.5 EKE39826.1 - 0.55 10.5 2.9 0.79 9.9 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Rubredoxin PF00301.15 EKE39826.1 - 2.8 7.8 5.8 63 3.5 4.0 2.3 1 1 0 1 1 1 0 Rubredoxin Ank_4 PF13637.1 EKE39827.1 - 6.2e-29 99.8 0.4 5.4e-09 36.3 0.0 4.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE39827.1 - 1.7e-27 95.6 0.1 1.8e-14 53.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE39827.1 - 1.7e-23 81.1 0.0 0.00029 20.4 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 EKE39827.1 - 1.9e-23 80.1 0.3 0.015 15.4 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EKE39827.1 - 1.1e-19 70.0 0.0 2.3e-07 30.8 0.0 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) DUF249 PF03158.8 EKE39827.1 - 0.0018 17.8 1.3 1.4 8.3 0.0 3.3 3 1 0 3 3 3 1 Multigene family 530 protein CoA_binding_2 PF13380.1 EKE39827.1 - 0.063 13.4 0.0 0.41 10.8 0.0 2.1 2 1 0 2 2 2 0 CoA binding domain DUF410 PF04190.8 EKE39827.1 - 0.081 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) IBR PF01485.16 EKE39828.1 - 1.2e-14 53.9 48.1 4e-09 36.2 7.8 4.4 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EKE39828.1 - 0.0016 18.3 5.1 0.0016 18.3 3.6 4.5 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) UBA PF00627.26 EKE39828.1 - 0.035 13.9 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain DUF4542 PF15075.1 EKE39828.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) zf-DHHC PF01529.15 EKE39830.1 - 1.2e-23 83.4 25.3 2.7e-22 79.0 17.5 2.1 1 1 0 1 1 1 1 DHHC palmitoyltransferase Rhodanese PF00581.15 EKE39831.1 - 1.9e-10 41.0 0.0 4.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase_Tyr PF07714.12 EKE39832.1 - 1.7e-56 191.1 0.0 3.2e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39832.1 - 6e-46 156.6 0.0 1.1e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FMN_red PF03358.10 EKE39833.1 - 5.4e-23 81.1 0.0 7.3e-23 80.7 0.0 1.3 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EKE39833.1 - 3.2e-15 56.1 0.0 4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EKE39833.1 - 0.00012 21.4 0.2 0.00077 18.8 0.1 2.0 2 0 0 2 2 2 1 Flavodoxin MFS_1 PF07690.11 EKE39834.1 - 4e-31 108.0 21.9 1.7e-21 76.3 2.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Oleosin PF01277.12 EKE39834.1 - 0.066 12.7 2.4 1.1 8.8 0.1 3.0 3 0 0 3 3 3 0 Oleosin Ank_2 PF12796.2 EKE39835.1 - 1e-19 70.6 0.0 1.3e-13 51.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKE39835.1 - 1.6e-16 59.1 0.0 1e-06 28.2 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EKE39835.1 - 5.4e-15 55.4 0.0 7e-08 32.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE39835.1 - 3.8e-14 52.3 0.0 1.2e-08 34.9 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE39835.1 - 3.3e-10 39.1 0.0 0.00081 19.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat DUF1854 PF08909.6 EKE39836.1 - 0.033 13.7 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) LRR_4 PF12799.2 EKE39839.1 - 1.7e-12 46.6 12.8 4.1e-07 29.4 0.4 4.6 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE39839.1 - 6.1e-11 41.9 11.5 3.7e-07 29.8 0.2 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EKE39839.1 - 4e-06 26.1 14.2 0.0032 17.2 0.0 6.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EKE39839.1 - 2.6e-05 23.6 6.3 0.31 11.4 0.0 5.9 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EKE39839.1 - 0.0056 16.6 9.9 1.5 9.1 0.0 5.7 6 0 0 6 6 6 2 Leucine Rich repeat eRF1_2 PF03464.10 EKE39839.1 - 0.034 14.4 0.1 0.08 13.2 0.1 1.6 1 0 0 1 1 1 0 eRF1 domain 2 A2L_zn_ribbon PF08792.5 EKE39839.1 - 0.09 12.2 0.5 0.19 11.2 0.3 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain TLD PF07534.11 EKE39841.1 - 2.2e-08 34.2 0.6 9.8e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 TLD DUF972 PF06156.8 EKE39841.1 - 0.0095 16.2 9.2 0.0095 16.2 6.4 3.1 1 1 2 3 3 2 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EKE39841.1 - 0.019 14.9 7.7 0.019 14.9 5.3 4.1 3 1 1 4 4 4 0 TSC-22/dip/bun family bZIP_1 PF00170.16 EKE39841.1 - 0.025 14.5 6.5 0.025 14.5 4.5 3.5 3 1 1 4 4 4 0 bZIP transcription factor PspB PF06667.7 EKE39841.1 - 0.14 12.1 6.1 1.1 9.2 1.6 2.7 1 1 1 2 2 2 0 Phage shock protein B DUF3086 PF11285.3 EKE39841.1 - 0.32 9.7 13.3 0.071 11.9 6.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Med9 PF07544.8 EKE39841.1 - 1.4 8.6 13.9 0.023 14.4 3.5 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HET PF06985.6 EKE39841.1 - 2 8.5 9.6 7.2 6.7 6.7 2.0 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Tweety PF04906.8 EKE39841.1 - 2.7 6.3 5.6 4.1 5.6 3.9 1.3 1 0 0 1 1 1 0 Tweety Exonuc_VII_L PF02601.10 EKE39841.1 - 3.5 6.7 17.5 5.3 6.1 12.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ApoO PF09769.4 EKE39841.1 - 4.3 7.0 10.5 0.72 9.5 1.0 2.2 2 0 0 2 2 2 0 Apolipoprotein O MCP_N PF05581.7 EKE39841.1 - 5.5 7.1 7.2 7.6 6.7 1.5 3.1 2 1 1 3 3 3 0 Vibrio chemotaxis protein N terminus IncA PF04156.9 EKE39841.1 - 6.1 6.3 28.6 0.026 14.1 9.8 2.3 1 1 1 2 2 1 0 IncA protein Erf4 PF10256.4 EKE39842.1 - 0.0069 16.2 3.1 0.11 12.4 1.0 2.7 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Arg_repressor PF01316.16 EKE39842.1 - 0.076 12.5 0.2 0.24 10.9 0.1 2.0 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DUF1931 PF09123.6 EKE39842.1 - 0.12 12.3 1.5 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) NPV_P10 PF05531.7 EKE39842.1 - 1 9.6 5.9 1.1 9.6 0.1 3.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Viral_cys_rich PF08008.7 EKE39842.1 - 1.3 8.6 5.8 4.9 6.8 0.2 3.0 3 1 0 3 3 3 0 Viral cysteine rich WD40 PF00400.27 EKE39844.1 - 3.2e-52 172.6 21.2 1.3e-10 40.7 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EKE39844.1 - 0.00053 18.2 9.0 0.35 8.9 2.3 4.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EKE39844.1 - 0.023 14.4 1.4 0.039 13.6 0.4 1.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ribosomal_L44 PF00935.14 EKE39846.1 - 9.7e-34 115.2 16.7 1.3e-33 114.7 11.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 EKE39846.1 - 0.0026 17.5 0.6 0.0026 17.5 0.4 2.3 1 1 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like FAM74 PF15026.1 EKE39846.1 - 0.063 12.9 0.7 0.08 12.5 0.5 1.1 1 0 0 1 1 1 0 FAM74 protein DUF329 PF03884.9 EKE39846.1 - 6.2 6.4 8.1 12 5.5 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF329) Pkinase_Tyr PF07714.12 EKE39847.1 - 2.7e-36 124.9 0.0 4.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39847.1 - 6.7e-32 110.6 0.2 1.4e-31 109.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 EKE39847.1 - 2.5e-10 40.2 0.9 2.5e-10 40.2 0.6 3.2 3 0 0 3 3 3 2 IPT/TIG domain DUF3149 PF11346.3 EKE39847.1 - 0.043 13.3 2.1 0.095 12.2 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) CotE PF10628.4 EKE39847.1 - 0.059 12.7 3.5 0.11 11.8 0.0 2.4 2 0 0 2 2 2 0 Outer spore coat protein E (CotE) DUF4389 PF14333.1 EKE39847.1 - 0.12 12.1 1.0 0.25 11.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) TMEM154 PF15102.1 EKE39847.1 - 0.16 11.6 3.0 0.33 10.6 2.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF3796 PF12676.2 EKE39847.1 - 0.18 12.0 3.6 0.44 10.7 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF1604 PF07713.8 EKE39848.1 - 3.5e-06 26.6 0.1 3.5e-06 26.6 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) SMC_N PF02463.14 EKE39849.1 - 9.4e-20 70.7 27.5 9.8e-16 57.6 0.2 4.4 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKE39849.1 - 2.5e-12 47.5 35.1 2.5e-12 47.5 24.3 6.8 1 1 3 4 4 4 1 AAA domain AAA_29 PF13555.1 EKE39849.1 - 0.0013 18.2 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EKE39849.1 - 0.0029 17.6 7.1 0.0029 17.6 4.9 5.6 2 2 1 4 4 4 1 AAA domain AAA_25 PF13481.1 EKE39849.1 - 0.021 14.2 0.2 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EKE39849.1 - 0.03 14.2 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EKE39849.1 - 0.33 9.3 0.0 0.17 10.3 10.1 5.9 4 2 2 6 6 6 0 AAA domain TLD PF07534.11 EKE39850.1 - 1.8e-07 31.2 0.3 3.4e-07 30.3 0.2 1.4 1 1 0 1 1 1 1 TLD Ras PF00071.17 EKE39851.1 - 3.6e-52 176.0 0.0 4.2e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39851.1 - 9.4e-14 51.9 0.0 2.2e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE39851.1 - 6.5e-12 45.0 0.0 8.4e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39851.1 - 1.7e-05 24.0 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE39851.1 - 0.0012 18.2 0.1 0.012 15.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKE39851.1 - 0.049 13.1 0.2 0.77 9.2 0.1 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Nop14 PF04147.7 EKE39851.1 - 0.064 11.1 0.0 0.08 10.8 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family Kri1_C PF12936.2 EKE39852.1 - 1.2e-22 79.6 2.6 1.2e-22 79.6 1.8 5.2 4 1 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EKE39852.1 - 2.3e-11 43.8 30.9 2.3e-11 43.8 21.4 6.1 3 3 3 6 6 6 1 KRI1-like family RNA_pol_Rpb4 PF03874.11 EKE39853.1 - 7.6e-08 32.3 1.2 1.1e-07 31.9 0.8 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Ribosomal_S28e PF01200.13 EKE39854.1 - 1.1e-28 98.7 2.8 1.1e-28 98.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e RhoGEF PF00621.15 EKE39855.1 - 2.3e-27 96.0 1.5 2.3e-27 96.0 1.0 2.6 2 0 0 2 2 2 1 RhoGEF domain HTH_7 PF02796.10 EKE39855.1 - 0.047 13.5 1.6 6.3 6.7 0.7 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Aa_trans PF01490.13 EKE39856.1 - 2e-14 52.9 32.7 2.5e-14 52.6 22.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EKE39856.1 - 1.1e-05 24.4 18.3 1.1e-05 24.4 12.7 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 EKE39856.1 - 0.19 10.2 47.3 0.043 12.3 25.7 2.6 1 1 1 2 2 2 0 Amino acid permease Lipase_3 PF01764.20 EKE39857.1 - 6.2e-20 71.2 0.0 1.5e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) RPAP1_N PF08621.5 EKE39857.1 - 0.13 11.8 0.3 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal FAM91_N PF14647.1 EKE39858.1 - 3.3e-26 92.0 5.9 4.3e-26 91.7 4.1 1.0 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.1 EKE39859.1 - 3.9e-33 114.9 1.4 2.1e-27 96.0 0.3 2.1 1 1 1 2 2 2 2 FAM91 C-terminus FixQ PF05545.6 EKE39860.1 - 0.0049 16.4 0.5 0.0089 15.6 0.3 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ LRRC37AB_C PF14914.1 EKE39860.1 - 0.0064 15.9 2.3 0.02 14.3 0.2 2.1 2 0 0 2 2 2 1 LRRC37A/B like protein 1 C-terminal domain TMEM154 PF15102.1 EKE39860.1 - 0.011 15.4 0.2 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Rax2 PF12768.2 EKE39860.1 - 0.019 14.2 0.8 0.026 13.7 0.6 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity DUF4064 PF13273.1 EKE39860.1 - 0.045 13.8 2.7 0.059 13.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3112 PF11309.3 EKE39860.1 - 0.05 13.4 0.5 0.084 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Tetraspannin PF00335.15 EKE39860.1 - 0.083 12.1 2.3 0.069 12.4 0.4 1.7 2 0 0 2 2 2 0 Tetraspanin family Phage_Gp23 PF10669.4 EKE39860.1 - 7.6 6.6 9.9 1.2 9.2 0.1 2.5 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RNA_pol_Rbc25 PF08292.7 EKE39862.1 - 7.6e-29 100.3 5.5 1.4e-27 96.3 2.1 2.5 2 1 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EKE39862.1 - 6.8e-06 26.1 0.1 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CytochromB561_N PF09786.4 EKE39862.1 - 0.012 14.1 0.7 0.015 13.7 0.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal BLVR PF06375.6 EKE39862.1 - 0.044 13.6 7.4 0.063 13.1 5.1 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) MIG-14_Wnt-bd PF06664.7 EKE39863.1 - 1.7e-06 27.1 42.7 1.7e-06 27.1 29.6 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Imm14 PF15428.1 EKE39863.1 - 0.0046 17.3 0.7 0.14 12.5 0.2 2.7 2 0 0 2 2 2 1 Immunity protein 14 LIM PF00412.17 EKE39864.1 - 7.9e-12 45.0 37.5 5.5e-07 29.5 11.4 2.8 3 0 0 3 3 3 2 LIM domain LCAT PF02450.10 EKE39865.1 - 1.7e-32 112.8 3.2 1.4e-28 99.9 0.4 2.0 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EKE39865.1 - 6.6e-06 25.8 0.0 2.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EKE39865.1 - 8.5e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE39865.1 - 0.0002 21.1 0.0 0.00043 20.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EKE39865.1 - 0.0008 18.7 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ser_hydrolase PF06821.8 EKE39865.1 - 0.0058 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase DUF900 PF05990.7 EKE39865.1 - 0.027 13.7 0.0 0.072 12.3 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EKE39865.1 - 0.043 13.4 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Glyco_hydro_77 PF02446.12 EKE39866.1 - 1.9e-45 155.4 3.7 7.6e-40 136.9 0.7 3.2 2 1 0 2 2 2 2 4-alpha-glucanotransferase CBM_20 PF00686.14 EKE39866.1 - 1.3e-11 43.9 0.3 5.6e-11 41.9 0.2 2.0 2 0 0 2 2 2 1 Starch binding domain DUF912 PF06024.7 EKE39867.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1517 PF07466.6 EKE39867.1 - 0.035 13.1 0.5 0.065 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) PPC PF04151.10 EKE39867.1 - 1.1 10.2 12.3 0.18 12.8 0.4 4.5 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain Histone PF00125.19 EKE39868.1 - 3.9e-16 58.9 0.0 8e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 She9_MDM33 PF05546.6 EKE39868.1 - 0.013 15.0 0.6 0.013 15.0 0.4 1.4 1 1 0 1 1 1 0 She9 / Mdm33 family CENP-S PF15630.1 EKE39868.1 - 0.017 15.3 0.3 0.017 15.3 0.2 2.1 2 0 0 2 2 2 0 Kinetochore component CENP-S DUF1664 PF07889.7 EKE39868.1 - 0.089 12.5 4.3 0.14 11.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2730 PF10805.3 EKE39868.1 - 0.089 12.5 7.9 0.025 14.3 2.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF948 PF06103.6 EKE39868.1 - 0.16 11.8 3.5 0.33 10.8 2.4 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.6 EKE39868.1 - 0.27 11.1 4.5 0.25 11.2 1.8 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.3 EKE39868.1 - 0.44 9.1 2.3 0.52 8.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3373 PF11853.3 EKE39868.1 - 0.75 8.2 3.0 0.94 7.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) APG6 PF04111.7 EKE39868.1 - 0.78 8.7 8.3 1.1 8.2 5.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EKE39868.1 - 1.1 7.0 6.6 1.2 6.9 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EKE39868.1 - 4.1 6.9 9.8 0.17 11.4 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.6 EKE39868.1 - 7.8 5.0 18.1 0.97 8.0 9.5 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein AA_kinase PF00696.23 EKE39869.1 - 7.7e-26 91.1 0.0 8.8e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family UQ_con PF00179.21 EKE39870.1 - 4e-39 133.2 0.1 4.6e-39 133.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EKE39870.1 - 0.0065 16.1 0.1 0.011 15.4 0.1 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 EKE39870.1 - 0.027 14.2 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B PTH2 PF01981.11 EKE39871.1 - 3.6e-23 81.4 0.1 4.3e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3296 PF11726.3 EKE39871.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Phytochelatin PF05023.9 EKE39871.1 - 0.034 13.1 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase DUF2404 PF10296.4 EKE39872.1 - 5.5e-15 55.2 0.2 5.5e-15 55.2 0.1 2.2 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) TM1586_NiRdase PF14512.1 EKE39872.1 - 0.02 14.0 0.2 0.26 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative TM nitroreductase Peptidase_M4_C PF02868.10 EKE39872.1 - 0.077 12.7 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain eIF-1a PF01176.14 EKE39873.1 - 1.4e-24 85.2 0.4 2e-24 84.7 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 EKE39874.1 - 6.7e-41 140.1 0.0 1.6e-40 138.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39874.1 - 2e-27 95.8 0.0 3.8e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE39874.1 - 0.00031 19.8 0.0 0.00066 18.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE39874.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Oest_recep PF02159.10 EKE39874.1 - 0.95 9.5 10.7 0.5 10.4 4.6 2.2 2 0 0 2 2 2 0 Oestrogen receptor Mem_trans PF03547.13 EKE39874.1 - 2.1 6.5 6.8 1.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Membrane transport protein YL1 PF05764.8 EKE39875.1 - 0.21 11.1 13.4 0.31 10.5 9.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2400 PF09674.5 EKE39875.1 - 0.29 10.7 4.5 0.38 10.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) APG6 PF04111.7 EKE39875.1 - 0.4 9.6 14.7 0.52 9.3 10.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Spt5_N PF11942.3 EKE39875.1 - 5.3 7.7 7.9 4.6 7.9 4.2 1.8 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF1664 PF07889.7 EKE39875.1 - 9.3 6.0 10.8 12 5.6 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PCYCGC PF13798.1 EKE39876.1 - 0.008 15.8 0.1 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function with PCYCGC motif zf-C3HC4_3 PF13920.1 EKE39877.1 - 1.3e-09 37.5 5.1 2e-09 36.9 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE39877.1 - 1.7e-09 37.5 11.5 2.7e-09 36.9 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE39877.1 - 3.3e-09 36.3 8.8 4.9e-09 35.7 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EKE39877.1 - 4e-06 26.3 10.6 7.6e-06 25.4 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE39877.1 - 5.2e-06 26.1 9.0 1e-05 25.2 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EKE39877.1 - 0.0002 21.1 4.1 0.00031 20.4 2.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EKE39877.1 - 0.00039 20.2 9.2 0.0016 18.2 6.4 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EKE39877.1 - 0.00068 19.1 5.2 0.0012 18.3 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EKE39877.1 - 0.0012 18.5 4.9 0.0026 17.4 3.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger NOB1_Zn_bind PF08772.6 EKE39877.1 - 0.0046 16.7 2.8 0.013 15.2 1.9 1.8 1 1 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF997 PF06196.7 EKE39877.1 - 0.0093 15.4 0.3 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF997) DUF1272 PF06906.6 EKE39877.1 - 0.073 12.9 6.0 0.12 12.2 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Cript PF10235.4 EKE39877.1 - 0.15 12.4 2.1 0.28 11.5 1.5 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT TerY-C PF15616.1 EKE39877.1 - 0.32 10.9 3.5 0.54 10.1 2.4 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zinc_ribbon_2 PF13240.1 EKE39877.1 - 0.51 9.8 0.1 0.51 9.8 0.1 2.9 2 1 1 3 3 3 0 zinc-ribbon domain IBR PF01485.16 EKE39877.1 - 1.2 9.0 9.3 3.4 7.5 3.7 2.5 1 1 1 2 2 2 0 IBR domain FANCL_C PF11793.3 EKE39877.1 - 6.7 6.7 10.4 2.2 8.2 0.8 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-ribbon_3 PF13248.1 EKE39877.1 - 7.9 5.8 9.5 7.9 5.8 5.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Pkinase_Tyr PF07714.12 EKE39878.1 - 1.3e-52 178.4 0.0 2.2e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39878.1 - 4.2e-49 167.0 0.0 7.7e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EKE39878.1 - 0.04 12.9 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RP-C_C PF11800.3 EKE39878.1 - 0.086 12.5 3.7 0.18 11.4 2.6 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region XPC-binding PF09280.6 EKE39878.1 - 0.13 11.7 0.2 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 XPC-binding domain ABC1 PF03109.11 EKE39878.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 ABC1 family vATP-synt_AC39 PF01992.11 EKE39879.1 - 0.011 14.9 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit JHBP PF06585.6 EKE39879.1 - 0.036 12.9 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) Folate_rec PF03024.9 EKE39879.1 - 0.085 12.4 0.2 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Folate receptor family DUP PF00674.13 EKE39880.1 - 0.27 11.2 3.6 8 6.4 0.3 2.6 2 1 0 2 2 2 0 DUP family TAFII55_N PF04658.8 EKE39883.1 - 1.6e-24 86.2 0.3 7.9e-24 83.9 0.2 1.8 1 1 0 1 1 1 1 TAFII55 protein conserved region Copine PF07002.11 EKE39885.1 - 8e-44 148.9 0.0 1.2e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EKE39885.1 - 1.4e-11 44.5 0.0 1.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EKE39885.1 - 0.0013 18.8 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE39885.1 - 0.0065 16.2 0.1 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain CTDII PF01556.13 EKE39886.1 - 0.00028 20.7 5.5 0.064 13.1 0.2 3.1 2 1 1 3 3 3 2 DnaJ C terminal domain Peptidase_M75 PF09375.5 EKE39886.1 - 0.082 12.2 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Imelysin IncA PF04156.9 EKE39887.1 - 0.012 15.2 18.1 0.012 15.2 12.5 1.9 1 1 1 2 2 2 0 IncA protein DUF4116 PF13475.1 EKE39887.1 - 0.016 14.6 0.1 0.41 10.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4503 PF14951.1 EKE39887.1 - 0.022 12.8 0.1 0.036 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Shugoshin_N PF07558.6 EKE39887.1 - 0.037 13.7 1.5 0.13 12.0 1.0 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF4094 PF13334.1 EKE39887.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DivIC PF04977.10 EKE39887.1 - 0.2 11.1 13.9 0.062 12.7 4.7 2.6 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 EKE39887.1 - 0.32 10.0 33.2 0.17 10.8 1.1 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 Syntaxin PF00804.20 EKE39887.1 - 1.1 9.4 13.4 3.2 7.9 9.3 1.8 1 1 0 1 1 1 0 Syntaxin Occludin_ELL PF07303.8 EKE39887.1 - 3.9 8.2 14.4 7.1 7.4 1.4 3.1 1 1 1 2 2 2 0 Occludin homology domain RNA_pol_Rpb1_5 PF04998.12 EKE39890.1 - 4.1e-84 282.1 0.0 1.2e-83 280.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EKE39890.1 - 6.9e-68 229.3 8.3 6.9e-68 229.3 5.8 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EKE39890.1 - 1e-64 217.4 0.2 4e-64 215.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EKE39890.1 - 9.2e-39 133.1 1.7 2e-38 132.0 0.9 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EKE39890.1 - 2e-37 128.3 0.1 7.1e-37 126.5 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EKE39890.1 - 1.2e-24 86.1 0.0 5.1e-24 84.0 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 EKE39890.1 - 8.6e-15 54.6 1.6 1.9e-14 53.5 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 AcetDehyd-dimer PF09290.6 EKE39890.1 - 0.096 12.5 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation HMG_box PF00505.14 EKE39891.1 - 6.5e-06 26.3 0.7 7.5e-06 26.1 0.5 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE39891.1 - 1.1e-05 25.7 0.9 1.3e-05 25.4 0.6 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EKE39892.1 - 0.38 11.0 8.3 0.86 9.9 1.5 3.0 2 2 1 3 3 3 0 HMG (high mobility group) box Fucose_iso_N2 PF07882.7 EKE39892.1 - 0.55 9.8 5.3 0.68 9.5 3.7 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain RRM_1 PF00076.17 EKE39893.1 - 5.9e-47 157.1 12.4 6.1e-16 57.8 1.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39893.1 - 4e-39 132.4 4.6 2.2e-12 46.7 0.2 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39893.1 - 1.2e-14 53.8 7.7 2.9e-05 23.8 0.0 4.1 3 2 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKE39893.1 - 3.4e-07 29.9 8.3 0.01 15.5 0.4 4.6 3 2 0 3 3 3 2 Limkain b1 DUF3804 PF12707.2 EKE39893.1 - 0.004 16.7 3.2 0.041 13.4 0.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3804) DUF1811 PF08838.5 EKE39893.1 - 0.011 15.7 3.8 0.28 11.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Thioredoxin_8 PF13905.1 EKE39893.1 - 0.93 9.6 3.9 0.82 9.8 0.4 2.6 2 1 1 3 3 3 0 Thioredoxin-like Metallophos PF00149.23 EKE39894.1 - 1.4e-11 44.1 3.6 2.4e-11 43.4 2.5 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE39894.1 - 1e-08 35.1 0.0 4.4e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DeoC PF01791.4 EKE39895.1 - 1.7e-57 194.4 8.2 1.9e-57 194.2 5.7 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase NanE PF04131.9 EKE39895.1 - 0.0056 15.6 3.0 0.0091 14.9 2.1 1.4 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase PcrB PF01884.12 EKE39895.1 - 0.026 13.7 1.3 0.048 12.8 0.1 1.8 1 1 0 2 2 2 0 PcrB family DHO_dh PF01180.16 EKE39895.1 - 0.035 13.0 2.7 0.1 11.5 0.3 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF1513 PF07433.6 EKE39895.1 - 0.039 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) TLD PF07534.11 EKE39896.1 - 7e-09 35.7 2.6 1.4e-08 34.8 1.8 1.5 1 0 0 1 1 1 1 TLD ABC_transp_aux PF09822.4 EKE39896.1 - 0.026 13.9 3.3 0.039 13.3 2.3 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system NdhM PF10664.4 EKE39896.1 - 1.8 8.4 6.7 4 7.4 2.5 2.7 1 1 2 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M Baculo_PEP_C PF04513.7 EKE39896.1 - 7.7 6.3 9.4 6 6.6 1.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Beach PF02138.13 EKE39897.1 - 6e-60 202.9 3.2 2e-59 201.2 2.2 2.0 1 0 0 1 1 1 1 Beige/BEACH domain Acyl_transf_1 PF00698.16 EKE39899.1 - 0.012 14.9 0.1 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase domain TK PF00265.13 EKE39899.1 - 0.091 12.3 0.3 0.091 12.3 0.2 1.9 2 0 0 2 2 2 0 Thymidine kinase Pkinase_Tyr PF07714.12 EKE39900.1 - 4.7e-54 183.1 0.4 5.5e-54 182.9 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE39900.1 - 1.8e-52 178.0 0.5 2.2e-52 177.8 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 EKE39900.1 - 0.0072 15.6 0.2 0.012 14.9 0.1 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EKE39900.1 - 0.045 12.8 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKE39900.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sec1 PF00995.18 EKE39901.1 - 3.6e-31 108.4 0.0 1.5e-30 106.4 0.0 1.8 1 1 0 1 1 1 1 Sec1 family HAD_2 PF13419.1 EKE39902.1 - 5.6e-18 65.7 0.0 7.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE39902.1 - 4.8e-09 36.9 0.2 1.2e-06 29.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE39902.1 - 6.2e-09 36.2 0.0 1.4e-08 35.1 0.0 1.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE39902.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EKE39902.1 - 0.0013 18.5 0.0 0.31 10.9 0.0 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EKE39902.1 - 0.0097 15.5 0.5 0.02 14.5 0.4 1.8 1 1 0 1 1 1 1 Acid Phosphatase Put_Phosphatase PF06888.7 EKE39902.1 - 0.016 14.4 1.0 0.061 12.4 0.7 1.8 1 1 0 1 1 1 0 Putative Phosphatase DUF3510 PF12022.3 EKE39902.1 - 0.068 13.2 0.1 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Hydrolase_3 PF08282.7 EKE39902.1 - 0.13 11.8 1.9 1.3 8.5 0.0 2.5 1 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase HTH_20 PF12840.2 EKE39903.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Ras PF00071.17 EKE39904.1 - 4.5e-54 182.2 0.7 5.4e-54 181.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39904.1 - 1.5e-15 57.7 0.0 2.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39904.1 - 5e-10 38.8 0.0 6.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE39904.1 - 1.6e-06 27.6 0.1 0.00014 21.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE39904.1 - 3.2e-06 26.4 0.1 4.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE39904.1 - 2.9e-05 23.9 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE39904.1 - 0.00018 20.7 1.5 0.00065 18.9 0.0 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKE39904.1 - 0.00074 19.0 0.0 0.099 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EKE39904.1 - 0.0014 19.4 0.0 0.0025 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EKE39904.1 - 0.0026 17.7 0.1 0.012 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EKE39904.1 - 0.0026 17.4 0.0 0.0086 15.7 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EKE39904.1 - 0.003 17.5 0.3 0.034 14.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EKE39904.1 - 0.0054 17.0 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKE39904.1 - 0.0055 16.8 0.0 0.082 13.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKE39904.1 - 0.0073 15.5 1.1 0.023 13.8 0.3 2.1 2 1 1 3 3 3 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EKE39904.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EKE39904.1 - 0.017 14.2 0.1 0.7 8.9 0.1 2.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 EKE39904.1 - 0.026 14.3 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EKE39904.1 - 0.032 13.2 1.0 0.036 13.0 0.0 1.5 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 EKE39904.1 - 0.041 12.7 0.1 0.21 10.3 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EKE39904.1 - 0.079 12.3 0.0 0.088 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain zf-Apc11 PF12861.2 EKE39905.1 - 0.2 11.5 7.4 0.36 10.6 5.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GRAM PF02893.15 EKE39906.1 - 5.2e-09 35.4 0.1 1.2e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 GRAM domain DUF3906 PF13046.1 EKE39907.1 - 0.18 11.4 2.2 0.2 11.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) MbeD_MobD PF04899.7 EKE39907.1 - 0.38 10.6 4.2 0.67 9.9 0.1 2.8 3 0 0 3 3 3 0 MbeD/MobD like eRF1_3 PF03465.10 EKE39907.1 - 9 6.5 8.5 0.41 10.9 0.5 2.5 2 1 0 2 2 2 0 eRF1 domain 3 zf-C2HC5 PF06221.8 EKE39908.1 - 3.6e-13 49.0 6.8 5.3e-13 48.5 4.7 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Yippee-Mis18 PF03226.9 EKE39909.1 - 0.0098 15.9 1.7 0.033 14.2 1.2 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Mu-like_Com PF10122.4 EKE39909.1 - 0.15 11.1 5.7 2.7 7.1 0.6 2.2 1 1 0 2 2 2 0 Mu-like prophage protein Com Rpr2 PF04032.11 EKE39909.1 - 1.2 9.0 4.0 2.2 8.2 0.2 2.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_5 PF13719.1 EKE39909.1 - 2.5 7.7 5.0 11 5.7 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Phosducin PF02114.11 EKE39910.1 - 7.3e-17 60.9 0.4 8.5e-17 60.7 0.3 1.2 1 0 0 1 1 1 1 Phosducin EF-1_beta_acid PF10587.4 EKE39910.1 - 0.0071 16.4 5.8 0.0071 16.4 4.0 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Rho_GDI PF02115.12 EKE39910.1 - 0.14 11.5 4.3 0.22 10.9 2.7 1.4 1 1 0 1 1 1 0 RHO protein GDP dissociation inhibitor Rifin_STEVOR PF02009.11 EKE39911.1 - 5.4e-05 22.9 0.0 5.4e-05 22.9 0.0 2.2 3 0 0 3 3 3 1 Rifin/stevor family TMEM154 PF15102.1 EKE39911.1 - 0.00025 20.7 0.2 0.00054 19.6 0.2 1.6 1 1 0 1 1 1 1 TMEM154 protein family ABC2_membrane_3 PF12698.2 EKE39911.1 - 0.0023 17.0 5.1 0.0032 16.5 3.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4064 PF13273.1 EKE39911.1 - 0.0034 17.4 0.2 0.0064 16.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF2970 PF11174.3 EKE39911.1 - 0.0068 15.9 0.5 0.011 15.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) Podoplanin PF05808.6 EKE39911.1 - 0.025 14.1 0.2 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF1191 PF06697.7 EKE39911.1 - 0.041 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CAML PF14963.1 EKE39911.1 - 0.043 13.1 0.9 0.086 12.1 0.6 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand AIF_C PF14721.1 EKE39911.1 - 0.18 12.0 3.0 0.3 11.3 1.4 1.8 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EphA2_TM PF14575.1 EKE39911.1 - 0.2 12.0 1.5 0.93 9.9 1.1 2.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF605 PF04652.11 EKE39911.1 - 0.3 10.4 16.3 0.41 9.9 11.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF912 PF06024.7 EKE39911.1 - 0.61 10.1 16.3 36 4.4 11.3 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDC45 PF02724.9 EKE39911.1 - 3.4 5.5 12.7 6.2 4.7 8.8 1.4 1 0 0 1 1 1 0 CDC45-like protein zf-UBR PF02207.15 EKE39912.1 - 1.2e-16 60.1 19.9 1.2e-16 60.1 13.8 3.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.1 EKE39912.1 - 9.3e-06 25.2 1.8 9.3e-06 25.2 1.2 4.4 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKE39912.1 - 1.7e-05 24.5 1.6 1.7e-05 24.5 1.1 4.3 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE39912.1 - 0.00015 21.7 2.5 0.00015 21.7 1.8 4.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE39912.1 - 0.00043 19.8 6.5 0.00043 19.8 4.5 4.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Polyoma_coat2 PF00761.15 EKE39912.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Polyomavirus coat protein CDC50 PF03381.10 EKE39913.1 - 2.3e-75 253.3 2.8 3.8e-75 252.6 1.7 1.5 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CUB_2 PF02408.15 EKE39913.1 - 0.022 14.2 1.6 0.06 12.8 1.1 1.9 1 1 0 1 1 1 0 CUB-like domain UPF0060 PF02694.10 EKE39913.1 - 0.031 14.2 0.6 0.083 12.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family IncA PF04156.9 EKE39913.1 - 7.7 6.0 8.6 6.8 6.2 0.3 2.3 2 0 0 2 2 2 0 IncA protein CAP_C PF08603.6 EKE39914.1 - 0.089 12.1 4.6 0.055 12.8 0.4 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal RNB PF00773.14 EKE39915.1 - 7.9e-18 64.8 0.6 2.1e-16 60.1 0.3 2.6 1 1 0 2 2 2 1 RNB domain HSP90 PF00183.13 EKE39916.1 - 2.5e-130 435.3 28.7 3.5e-130 434.9 19.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EKE39916.1 - 7.1e-14 51.6 0.3 7.1e-14 51.6 0.2 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKE39916.1 - 1e-06 28.4 0.1 2.4e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RIH_assoc PF08454.6 EKE39916.1 - 0.043 13.4 0.0 0.23 11.0 0.0 2.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated Polyketide_cyc PF03364.15 EKE39916.1 - 0.13 12.2 0.8 0.34 10.8 0.5 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport GCD14 PF08704.5 EKE39916.1 - 9.8 5.5 8.8 1.8 8.0 3.2 1.9 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Fcf1 PF04900.7 EKE39917.1 - 0.047 13.7 4.0 0.17 11.9 0.8 2.8 2 1 0 2 2 2 0 Fcf1 GATase PF00117.23 EKE39917.1 - 0.065 12.6 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DUF4107 PF13389.1 EKE39917.1 - 0.13 11.9 0.8 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) Herpes_pp85 PF04637.7 EKE39918.1 - 0.0043 15.4 0.1 0.0056 15.0 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF648 PF04890.8 EKE39918.1 - 0.01 15.0 5.6 0.012 14.8 3.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF2621 PF11084.3 EKE39918.1 - 0.13 11.9 1.2 0.18 11.4 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2621) DUF4446 PF14584.1 EKE39918.1 - 0.32 10.8 13.9 1.8 8.4 0.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF4446) Fib_alpha PF08702.5 EKE39918.1 - 1.1 9.3 12.4 1.7 8.7 3.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.16 EKE39918.1 - 6.4 6.2 9.2 50 3.3 6.4 2.2 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IncA PF04156.9 EKE39918.1 - 7.5 6.0 16.9 2.2 7.8 2.6 2.3 1 1 1 2 2 2 0 IncA protein Pkinase PF00069.20 EKE39919.1 - 1.5e-46 158.6 0.0 2.6e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39919.1 - 1.6e-30 106.0 0.0 2.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 EKE39919.1 - 7.7e-28 96.9 0.4 1.6e-27 95.9 0.3 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Kinase-like PF14531.1 EKE39919.1 - 1.9e-06 27.0 0.0 3.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE39919.1 - 0.00066 19.4 0.0 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family PQQ_2 PF13360.1 EKE39919.1 - 0.0022 17.4 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain Kdo PF06293.9 EKE39919.1 - 0.035 13.1 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MacB_PCD PF12704.2 EKE39919.1 - 0.047 13.2 0.3 0.086 12.4 0.2 1.3 1 0 0 1 1 1 0 MacB-like periplasmic core domain ODV-E18 PF10717.4 EKE39919.1 - 0.51 9.8 4.9 1.3 8.5 3.4 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 adh_short PF00106.20 EKE39921.1 - 3e-10 40.2 0.3 1.1e-09 38.3 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EKE39921.1 - 1e-09 38.2 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKE39921.1 - 1.8e-08 34.5 0.0 3.2e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EKE39921.1 - 0.012 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKE39921.1 - 0.016 14.9 0.8 0.15 11.7 0.6 2.1 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 EKE39921.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GRDA PF04723.9 EKE39921.1 - 0.067 12.9 0.2 0.094 12.4 0.2 1.2 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A Nodulin_late PF07127.6 EKE39921.1 - 0.083 13.0 0.4 0.083 13.0 0.3 2.3 2 0 0 2 2 2 0 Late nodulin protein JAB PF01398.16 EKE39922.1 - 2.8e-34 117.2 0.1 6.2e-34 116.1 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EKE39922.1 - 1.2e-15 57.5 1.5 3.1e-15 56.2 1.1 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EKE39922.1 - 1.7e-10 40.3 0.0 3.8e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EKE39922.1 - 0.014 14.9 0.1 0.021 14.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) CH PF00307.26 EKE39923.1 - 2.7e-14 53.1 0.2 3.2e-06 27.1 0.0 2.7 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKE39923.1 - 0.0012 18.4 0.0 0.006 16.2 0.0 2.2 2 0 0 2 2 2 1 CAMSAP CH domain PH PF00169.24 EKE39923.1 - 0.016 15.4 0.5 0.042 14.0 0.4 1.7 1 0 0 1 1 1 0 PH domain Thermopsin PF05317.6 EKE39923.1 - 0.048 12.5 2.8 0.084 11.7 1.9 1.3 1 0 0 1 1 1 0 Thermopsin DnaJ PF00226.26 EKE39924.1 - 2.5e-25 87.9 0.7 8e-25 86.3 0.5 1.9 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 EKE39924.1 - 2.8e-09 36.8 5.9 5.5e-09 35.9 4.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EKE39924.1 - 3.6e-09 36.4 6.8 3.6e-09 36.4 4.7 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EKE39924.1 - 0.00024 21.1 6.3 0.00067 19.7 4.0 2.1 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EKE39924.1 - 0.0012 19.0 1.9 0.0037 17.4 1.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EKE39924.1 - 0.05 13.9 2.5 0.11 12.9 1.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nitroreductase PF00881.19 EKE39925.1 - 4e-33 114.5 0.0 4.5e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family DUF4320 PF14208.1 EKE39925.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF1342 PF07072.6 EKE39926.1 - 0.14 11.8 1.7 2.6 7.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) vATP-synt_AC39 PF01992.11 EKE39927.1 - 1.9e-88 296.7 2.5 2.2e-88 296.6 1.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ras PF00071.17 EKE39928.1 - 1.5e-46 157.7 1.2 1.7e-46 157.5 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39928.1 - 1.2e-20 74.2 1.0 1.6e-20 73.7 0.7 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39928.1 - 3.5e-11 42.6 0.1 4.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKE39928.1 - 2e-06 27.1 0.2 2.7e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE39928.1 - 4e-06 26.3 0.7 0.00019 20.9 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE39928.1 - 1.1e-05 24.7 0.4 1.5e-05 24.2 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE39928.1 - 0.00013 21.9 0.6 0.00023 21.1 0.3 1.5 1 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EKE39928.1 - 0.00061 19.4 0.7 0.013 15.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EKE39928.1 - 0.00061 19.9 0.0 0.0031 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EKE39928.1 - 0.0012 17.8 0.1 0.0023 17.0 0.1 1.4 1 0 0 1 1 1 1 Septin SRP54 PF00448.17 EKE39928.1 - 0.002 17.5 0.5 0.52 9.7 0.1 2.4 1 1 1 2 2 2 2 SRP54-type protein, GTPase domain IIGP PF05049.8 EKE39928.1 - 0.0028 16.5 0.1 0.0041 15.9 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EKE39928.1 - 0.006 16.5 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EKE39928.1 - 0.017 14.6 0.8 0.023 14.2 0.5 1.6 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EKE39928.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 EKE39928.1 - 0.035 13.8 0.2 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 NTPase G-alpha PF00503.15 EKE39928.1 - 0.038 12.6 1.0 1.3 7.6 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 EKE39928.1 - 0.038 13.1 0.1 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EKE39928.1 - 0.048 13.3 0.2 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EKE39928.1 - 0.055 12.7 0.1 4.9 6.4 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B VRP1 PF03538.9 EKE39928.1 - 0.057 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein Zeta_toxin PF06414.7 EKE39928.1 - 0.059 12.4 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 EKE39928.1 - 0.092 12.2 0.1 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EKE39928.1 - 0.099 12.3 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase GalKase_gal_bdg PF10509.4 EKE39929.1 - 1.7e-22 78.3 0.1 3.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EKE39929.1 - 1.3e-11 44.4 0.0 3e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EKE39929.1 - 6.3e-10 38.9 0.2 1.7e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Aldose_epim PF01263.15 EKE39930.1 - 9e-79 264.6 1.3 1e-78 264.5 0.9 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase LRR_5 PF13306.1 EKE39931.1 - 4.4e-59 197.8 50.2 8.5e-33 112.8 7.4 6.2 3 3 3 6 6 6 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE39931.1 - 1e-10 41.1 6.0 6e-05 22.7 0.2 3.7 2 1 2 4 4 4 3 Leucine rich repeat CH PF00307.26 EKE39932.1 - 1.6e-22 79.6 0.3 3.4e-10 39.9 0.0 3.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKE39932.1 - 5.5e-06 25.9 0.0 0.11 12.1 0.0 3.2 2 0 0 2 2 2 2 CAMSAP CH domain HEAT PF02985.17 EKE39933.1 - 4.7e-12 44.9 1.6 0.0013 18.6 0.0 8.6 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.1 EKE39933.1 - 3.9e-11 43.0 0.0 0.013 15.8 0.0 7.5 7 2 0 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 EKE39933.1 - 7.7e-09 35.7 2.5 2.3 8.8 0.0 7.9 10 0 0 10 10 10 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EKE39933.1 - 0.00017 21.9 6.8 23 5.4 0.0 6.4 4 2 3 7 7 7 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EKE39933.1 - 0.019 14.9 0.0 3.6 7.5 0.0 3.5 3 0 0 3 3 3 0 V-ATPase subunit H DUF2435 PF10363.4 EKE39933.1 - 0.036 13.9 0.6 13 5.8 0.1 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2435) Urb2 PF10441.4 EKE39933.1 - 0.051 13.1 1.4 1.2 8.7 0.2 3.5 3 1 1 4 4 4 0 Urb2/Npa2 family Arm PF00514.18 EKE39933.1 - 0.057 13.2 10.5 9.1 6.2 0.0 6.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat FAD_binding_5 PF00941.16 EKE39934.1 - 0.0084 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Golgin_A5 PF09787.4 EKE39934.1 - 0.011 14.3 3.2 0.013 14.0 2.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Bacillus_HBL PF05791.6 EKE39934.1 - 0.024 14.0 8.1 0.64 9.3 5.6 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) EXOSC1 PF10447.4 EKE39934.1 - 0.044 13.7 0.1 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 SPAM PF02090.10 EKE39934.1 - 0.72 9.8 5.5 0.72 9.8 2.6 1.7 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein HR1 PF02185.11 EKE39934.1 - 1.9 8.3 12.9 4.8 7.0 2.3 2.7 1 1 2 3 3 3 0 Hr1 repeat DUF2648 PF10855.3 EKE39935.1 - 0.0038 16.6 2.1 0.0094 15.3 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2648) EpuA PF11772.3 EKE39935.1 - 9.3 5.7 12.0 22 4.5 8.3 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta XRN_N PF03159.13 EKE39937.1 - 3e-97 324.6 0.0 3e-97 324.6 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Phosphoesterase PF04185.9 EKE39937.1 - 0.13 11.3 1.2 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Phosphoesterase family ALMT PF11744.3 EKE39938.1 - 0.017 13.8 1.6 0.018 13.7 1.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SGL PF08450.7 EKE39938.1 - 0.018 14.3 0.1 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region BBS2_Mid PF14783.1 EKE39938.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region STAT_alpha PF01017.15 EKE39938.1 - 0.046 13.4 7.3 0.083 12.5 5.0 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain Lipase_GDSL_3 PF14606.1 EKE39938.1 - 0.79 9.4 3.9 1.5 8.5 2.7 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4482 PF14818.1 EKE39938.1 - 2.2 8.9 10.5 7.4 7.2 7.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) GTP_EFTU_D3 PF03143.12 EKE39939.1 - 0.0054 16.8 0.1 0.18 12.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Bud13 PF09736.4 EKE39940.1 - 1.5 9.0 12.0 2.8 8.2 8.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ras PF00071.17 EKE39941.1 - 2.5e-61 205.7 0.6 3e-61 205.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39941.1 - 2.7e-19 69.8 0.0 5.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39941.1 - 6.2e-15 54.8 0.1 7.9e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39941.1 - 3.1e-06 26.5 0.0 4.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE39941.1 - 4.1e-05 23.5 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE39941.1 - 8.2e-05 22.1 0.1 0.00019 20.9 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EKE39941.1 - 0.0037 17.5 0.0 0.023 14.9 0.0 1.9 1 1 1 2 2 2 1 ABC transporter SRPRB PF09439.5 EKE39941.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EKE39941.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKE39941.1 - 0.02 14.0 0.1 0.044 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EKE39941.1 - 0.049 13.3 0.3 0.11 12.1 0.1 1.5 1 1 1 2 2 2 0 Archaeal ATPase FeoB_N PF02421.13 EKE39941.1 - 0.051 12.8 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 EKE39941.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKE39941.1 - 0.069 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNase_E_G PF10150.4 EKE39941.1 - 0.083 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family PduV-EutP PF10662.4 EKE39941.1 - 0.1 12.0 0.1 0.55 9.7 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EKE39941.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.2 EKE39943.1 - 2.1e-23 82.4 5.0 1.6e-11 44.4 0.2 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKE39943.1 - 1.8e-20 71.6 9.9 3e-05 23.5 0.2 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EKE39943.1 - 4.1e-19 68.1 6.5 7.9e-08 32.3 0.3 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKE39943.1 - 1.2e-14 54.3 10.9 2.3e-05 24.7 1.9 4.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE39943.1 - 3.8e-13 48.2 11.4 0.00065 19.6 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ribosomal_S17e PF00833.13 EKE39944.1 - 1.3e-37 128.2 2.8 1.6e-37 127.9 2.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Pkinase PF00069.20 EKE39945.1 - 1.5e-55 188.1 0.0 2.7e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39945.1 - 5.4e-51 173.1 0.0 8.6e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4010 PF13194.1 EKE39945.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) EphA2_TM PF14575.1 EKE39945.1 - 0.081 13.3 0.1 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.1 EKE39945.1 - 0.1 12.7 0.3 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YajC PF02699.10 EKE39945.1 - 0.14 11.8 0.2 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Preprotein translocase subunit VSP PF03302.8 EKE39945.1 - 0.98 7.9 175.9 0.045 12.3 19.5 7.9 1 1 4 7 7 7 0 Giardia variant-specific surface protein SKG6 PF08693.5 EKE39945.1 - 2.7 7.3 7.9 5.1 6.4 5.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AntA PF08346.7 EKE39946.1 - 2.4 8.4 4.6 1 9.5 0.2 2.5 3 0 0 3 3 3 0 AntA/AntB antirepressor zinc_ribbon_2 PF13240.1 EKE39947.1 - 3.1e-07 29.6 4.6 1.9e-06 27.1 0.5 2.6 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 EKE39947.1 - 7.1e-05 21.8 2.1 7.1e-05 21.8 1.4 2.3 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 EKE39947.1 - 0.00066 19.4 0.7 0.00066 19.4 0.5 2.4 2 1 0 2 2 2 1 Double zinc ribbon Toxin-deaminase PF14424.1 EKE39947.1 - 0.0062 16.5 2.7 0.011 15.6 1.9 1.5 1 1 0 1 1 1 1 The BURPS668_1122 family of deaminases LIM PF00412.17 EKE39947.1 - 0.0072 16.3 1.2 0.0072 16.3 0.9 2.2 2 1 0 2 2 2 1 LIM domain zf-NADH-PPase PF09297.6 EKE39947.1 - 0.022 14.2 0.3 0.069 12.6 0.0 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.4 EKE39947.1 - 0.025 14.2 2.5 0.058 13.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pox_A11 PF05061.8 EKE39947.1 - 0.073 12.1 0.2 0.083 11.9 0.2 1.0 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF3659 PF12396.3 EKE39947.1 - 0.14 11.8 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Clenterotox PF03505.9 EKE39947.1 - 0.28 10.5 2.2 0.4 10.0 1.6 1.3 1 1 0 1 1 1 0 Clostridium enterotoxin zf-C2HC5 PF06221.8 EKE39947.1 - 0.29 10.9 3.4 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-IS66 PF13005.2 EKE39947.1 - 0.47 10.4 4.2 7.9 6.5 0.1 3.3 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Cript PF10235.4 EKE39947.1 - 2.9 8.3 9.8 16 5.9 4.6 2.7 1 1 0 2 2 2 0 Microtubule-associated protein CRIPT Draxin PF15550.1 EKE39948.1 - 3.2 7.3 21.9 5.6 6.5 15.2 1.4 1 1 0 1 1 1 0 Draxin Ras PF00071.17 EKE39949.1 - 3e-22 78.7 0.5 4.5e-22 78.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39949.1 - 6.3e-11 42.8 0.0 1.2e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39949.1 - 5.6e-10 38.7 0.8 8.7e-10 38.1 0.5 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39949.1 - 3.8e-07 29.4 0.6 5.3e-07 29.0 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE39949.1 - 3.5e-05 23.0 0.9 4.9e-05 22.6 0.4 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE39949.1 - 0.00027 20.4 0.3 0.0012 18.3 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE39949.1 - 0.0011 18.9 0.3 0.0024 17.8 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 EKE39949.1 - 0.0083 15.5 1.0 0.073 12.5 0.2 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKE39949.1 - 0.039 14.0 0.1 0.074 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKE39949.1 - 0.045 13.6 0.4 0.11 12.4 0.2 1.8 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EKE39949.1 - 0.085 12.5 7.1 0.017 14.8 2.3 1.8 2 1 0 2 2 2 0 Archaeal ATPase Stathmin PF00836.14 EKE39949.1 - 0.29 10.7 2.7 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Stathmin family SPRY PF00622.23 EKE39950.1 - 3.6e-07 30.3 0.6 6.7e-07 29.4 0.4 1.5 1 0 0 1 1 1 1 SPRY domain Inhibitor_I42 PF09394.5 EKE39951.1 - 3.9e-22 78.3 0.0 4.7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Ras PF00071.17 EKE39952.1 - 9.2e-48 161.6 0.3 1.1e-47 161.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE39952.1 - 2e-17 63.7 0.0 3.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE39952.1 - 3.7e-11 42.5 0.0 5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE39952.1 - 2e-06 27.1 0.2 2.5e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE39952.1 - 3.1e-06 26.7 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE39952.1 - 3.6e-05 23.0 0.5 5.2e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit NOG1 PF06858.9 EKE39952.1 - 0.0002 21.1 0.1 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) G-alpha PF00503.15 EKE39952.1 - 0.012 14.3 1.7 0.014 14.0 1.2 1.3 1 0 0 1 1 1 0 G-protein alpha subunit MTS_N PF08468.6 EKE39952.1 - 0.075 12.8 0.4 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal Acetyltransf_4 PF13420.1 EKE39952.1 - 0.088 12.7 1.1 0.17 11.8 0.6 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF912 PF06024.7 EKE39953.1 - 0.003 17.5 0.1 0.0082 16.1 0.0 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) GH97_C PF14509.1 EKE39953.1 - 0.044 13.8 0.0 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF2970 PF11174.3 EKE39953.1 - 0.045 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF2839 PF10999.3 EKE39953.1 - 0.069 13.1 0.0 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF3827 PF12877.2 EKE39953.1 - 0.085 10.9 0.1 0.14 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SNase PF00565.12 EKE39954.1 - 6.1e-26 90.8 26.9 1.2e-08 35.1 0.5 5.7 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EKE39954.1 - 2.2e-05 24.3 3.0 7.8e-05 22.4 0.0 2.9 2 1 1 3 3 3 1 Tudor domain START PF01852.14 EKE39955.1 - 1.2e-22 80.2 0.0 1.5e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 START domain DUF2838 PF10998.3 EKE39956.1 - 1.1e-25 89.7 11.2 1.1e-25 89.7 7.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Pkinase PF00069.20 EKE39957.1 - 1.4e-45 155.4 10.9 7.5e-39 133.4 0.2 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE39957.1 - 2.5e-25 89.0 8.5 8e-20 71.0 0.0 3.8 4 0 0 4 4 4 2 Protein tyrosine kinase VPS28 PF03997.7 EKE39958.1 - 4.3e-06 26.4 0.9 7.3e-06 25.7 0.6 1.4 1 1 0 1 1 1 1 VPS28 protein Pox_C7_F8A PF03287.9 EKE39958.1 - 0.013 15.2 4.4 0.021 14.5 0.4 2.2 1 1 0 2 2 2 0 Poxvirus C7/F8A protein THF_DHG_CYH_C PF02882.14 EKE39958.1 - 0.14 11.2 0.1 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PH PF00169.24 EKE39959.1 - 0.082 13.1 3.8 0.21 11.7 2.6 1.8 1 1 0 1 1 1 0 PH domain RNA_pol_Rpb1_5 PF04998.12 EKE39959.1 - 0.24 10.6 1.0 0.37 10.0 0.7 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Takusan PF04822.8 EKE39960.1 - 0.06 13.1 0.3 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Takusan RP-C_C PF11800.3 EKE39961.1 - 3.5 7.2 10.7 0.36 10.4 4.5 1.6 2 1 0 2 2 2 0 Replication protein C C-terminal region XRN_N PF03159.13 EKE39962.1 - 4.5e-68 229.1 8.1 7.2e-36 123.7 0.1 2.9 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus RHD3 PF05879.7 EKE39963.1 - 5.3e-140 467.7 19.8 6.8e-140 467.3 13.8 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 EKE39963.1 - 3.8e-05 23.6 0.0 0.0002 21.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKE39963.1 - 0.0021 17.9 0.9 0.022 14.6 0.0 3.1 3 1 0 3 3 3 1 Dynamin family Miro PF08477.8 EKE39963.1 - 0.0054 17.2 0.0 0.024 15.1 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 EKE39963.1 - 0.013 15.3 0.6 0.17 11.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EKE39963.1 - 0.016 14.6 0.2 0.14 11.5 0.1 2.4 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EKE39963.1 - 0.077 13.1 0.4 2.4 8.2 0.0 3.2 3 1 0 3 3 3 0 AAA domain NOG1 PF06858.9 EKE39964.1 - 4e-26 90.6 0.1 1.2e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EKE39964.1 - 3.3e-18 65.7 0.1 1.3e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOGCT PF08155.6 EKE39964.1 - 2e-15 56.2 4.8 4.9e-15 54.9 3.3 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.13 EKE39964.1 - 2.9e-10 39.6 0.0 7.3e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 EKE39964.1 - 0.0049 15.9 0.7 0.014 14.5 0.0 2.1 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 EKE39964.1 - 0.015 14.6 0.2 0.093 12.1 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EKE39964.1 - 0.019 14.1 0.0 0.099 11.8 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EKE39964.1 - 0.027 14.9 0.0 0.074 13.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF4473 PF14747.1 EKE39964.1 - 0.95 9.7 5.4 2.9 8.1 0.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) TFIIF_beta PF02270.10 EKE39965.1 - 9.4e-13 48.5 5.2 9.4e-13 48.5 3.6 2.0 1 1 1 2 2 2 1 Transcription initiation factor IIF, beta subunit Ribosomal_L24e PF01246.15 EKE39966.1 - 5.6e-31 106.2 3.8 1.1e-30 105.2 2.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF2175 PF09943.4 EKE39966.1 - 0.014 15.4 1.2 0.014 15.4 0.8 2.5 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) UPF1_Zn_bind PF09416.5 EKE39966.1 - 0.033 13.7 0.8 0.071 12.6 0.2 1.7 1 1 1 2 2 2 0 RNA helicase (UPF2 interacting domain) Arc_trans_TRASH PF08394.5 EKE39966.1 - 0.057 13.5 1.0 0.13 12.3 0.7 1.7 1 0 0 1 1 1 0 Archaeal TRASH domain Phage_Gp15 PF06854.6 EKE39967.1 - 0.026 14.0 3.0 0.035 13.6 2.1 1.2 1 0 0 1 1 1 0 Bacteriophage Gp15 protein MFS_1 PF07690.11 EKE39968.1 - 1.6e-26 92.8 69.3 1.4e-25 89.7 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKE39968.1 - 2.1e-11 43.0 23.5 2.3e-10 39.6 8.6 2.9 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EKE39968.1 - 0.00053 19.7 1.4 0.29 10.9 0.0 3.5 2 1 1 3 3 3 2 MFS_1 like family FAM176 PF14851.1 EKE39968.1 - 0.01 15.5 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 FAM176 family Acetyltransf_1 PF00583.19 EKE39969.1 - 7.3e-14 51.5 0.0 7.7e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKE39969.1 - 8.4e-07 28.6 0.1 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EKE39969.1 - 5.4e-05 23.3 0.0 5.9e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EKE39969.1 - 0.0009 18.9 0.1 0.0025 17.5 0.1 1.6 1 1 1 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.1 EKE39969.1 - 0.0041 16.9 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKE39969.1 - 0.005 17.0 0.0 0.005 17.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKE39969.1 - 0.0055 16.6 0.0 0.0066 16.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKE39969.1 - 0.0066 16.3 0.0 0.0083 16.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKE39969.1 - 0.037 14.1 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4166 PF13761.1 EKE39969.1 - 0.069 13.0 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) PX PF00787.19 EKE39970.1 - 2.7e-10 40.0 0.8 2.7e-10 40.0 0.5 2.0 2 0 0 2 2 2 1 PX domain Methyltransf_19 PF04672.7 EKE39970.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase GxGYxYP PF14323.1 EKE39971.1 - 0.0012 17.6 6.6 0.0017 17.1 4.6 1.1 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function DUF2791 PF10923.3 EKE39971.1 - 0.002 16.8 1.0 0.0027 16.3 0.7 1.4 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) Syntaxin-6_N PF09177.6 EKE39971.1 - 0.003 17.9 7.5 0.0092 16.3 0.1 2.8 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF3287 PF11690.3 EKE39971.1 - 0.01 15.8 0.8 0.01 15.8 0.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) Syntaxin-18_N PF10496.4 EKE39971.1 - 0.1 12.4 5.8 0.85 9.4 0.5 3.2 1 1 2 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus GrpE PF01025.14 EKE39971.1 - 0.38 10.2 16.6 0.057 12.9 5.5 2.6 2 2 0 2 2 2 0 GrpE P4Ha_N PF08336.6 EKE39971.1 - 0.6 9.9 9.9 0.64 9.8 1.5 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF948 PF06103.6 EKE39971.1 - 0.81 9.5 5.0 1.7 8.5 0.8 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Toxin_52 PF15605.1 EKE39971.1 - 1.9 8.3 8.9 1.8 8.5 0.7 3.0 2 1 1 3 3 3 0 Putative toxin 52 MerR-DNA-bind PF09278.6 EKE39971.1 - 2.5 8.5 5.6 4.8 7.6 0.2 2.9 3 0 0 3 3 2 0 MerR, DNA binding DUF1798 PF08807.5 EKE39971.1 - 2.9 7.6 9.0 0.16 11.6 1.0 2.5 2 1 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Topoisom_I PF01028.15 EKE39971.1 - 3.6 6.6 8.6 0.86 8.6 2.2 2.1 1 1 1 2 2 2 0 Eukaryotic DNA topoisomerase I, catalytic core Syntaxin PF00804.20 EKE39971.1 - 3.9 7.6 19.1 4.5 7.4 8.1 2.9 2 1 0 2 2 2 0 Syntaxin DNA_topoisoIV PF00521.15 EKE39971.1 - 3.9 6.2 12.0 7.7 5.2 8.3 1.4 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Nsp1_C PF05064.8 EKE39971.1 - 4.8 6.8 14.9 0.13 11.9 4.2 2.7 2 2 2 4 4 4 0 Nsp1-like C-terminal region DUF1690 PF07956.6 EKE39971.1 - 5 7.1 13.2 2.6 8.0 4.8 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Tropomyosin_1 PF12718.2 EKE39971.1 - 5 6.9 15.9 3.7 7.3 5.6 2.4 2 1 0 2 2 2 0 Tropomyosin like Prefoldin_2 PF01920.15 EKE39971.1 - 9.6 6.0 22.8 0.67 9.7 4.8 3.6 3 1 1 4 4 4 0 Prefoldin subunit LSM PF01423.17 EKE39972.1 - 1.1e-15 56.8 0.4 1.3e-15 56.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain Sialidase PF02973.11 EKE39972.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Sialidase, N-terminal domain ATP_bind_1 PF03029.12 EKE39973.1 - 5.8e-56 189.7 0.0 7e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EKE39973.1 - 0.0012 17.7 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_21 PF13304.1 EKE39973.1 - 0.0019 18.2 1.3 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKE39973.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Viral_helicase1 PF01443.13 EKE39973.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EKE39973.1 - 0.013 14.9 0.1 0.08 12.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EKE39973.1 - 0.017 14.8 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 EKE39973.1 - 0.019 14.7 0.2 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EKE39973.1 - 0.022 14.4 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EKE39973.1 - 0.025 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EKE39973.1 - 0.026 15.3 3.0 0.057 14.2 1.1 2.3 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKE39973.1 - 0.034 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EKE39973.1 - 0.058 13.5 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EKE39973.1 - 0.06 12.9 0.3 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EKE39973.1 - 0.078 12.9 0.4 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EKE39973.1 - 0.086 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EKE39973.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKE39973.1 - 0.1 12.8 1.0 0.3 11.3 0.6 1.8 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 EKE39973.1 - 0.13 12.2 0.2 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 EKE39973.1 - 0.14 11.8 0.1 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EKE39973.1 - 0.23 11.7 2.2 0.37 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.18 EKE39974.1 - 7.3e-19 68.6 0.0 2e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EKE39974.1 - 1.7e-05 24.4 0.3 3.7e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain SEA PF01390.15 EKE39974.1 - 0.0015 18.2 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 SEA domain SHS2_Rpb7-N PF03876.12 EKE39974.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 E1-E2_ATPase PF00122.15 EKE39975.1 - 1.2e-14 53.9 0.1 1.3e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EKE39975.1 - 2.7e-13 50.5 0.0 2.6e-12 47.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE39975.1 - 6.6e-12 46.2 0.0 1.1e-07 32.5 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE39975.1 - 6.4e-09 35.6 0.0 2.7e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit TLD PF07534.11 EKE39976.1 - 1.6e-07 31.4 0.1 4e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 TLD Nipped-B_C PF12830.2 EKE39977.1 - 3.1e-30 105.2 4.5 3.1e-30 105.2 3.1 4.0 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EKE39977.1 - 4.9e-10 39.1 7.2 5.3e-09 35.8 1.2 4.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EKE39977.1 - 0.00011 21.9 1.7 4.2 7.6 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EKE39977.1 - 0.00052 20.2 3.7 0.36 11.1 0.2 4.9 4 1 1 5 5 5 1 HEAT repeats GlutR_dimer PF00745.15 EKE39977.1 - 0.019 14.9 3.4 0.034 14.0 0.8 2.6 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain TLD PF07534.11 EKE39978.1 - 7.5e-05 22.7 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 TLD DUF4407 PF14362.1 EKE39978.1 - 0.06 12.2 0.1 0.074 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) STAT_alpha PF01017.15 EKE39978.1 - 0.072 12.8 2.5 0.11 12.1 1.7 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain Syntaxin-6_N PF09177.6 EKE39978.1 - 0.76 10.2 4.3 3.2 8.2 0.7 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3552 PF12072.3 EKE39978.1 - 1.5 7.9 9.6 4.8 6.3 6.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Acetyltransf_13 PF13880.1 EKE39979.1 - 7.1e-16 57.7 0.0 1.4e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EKE39979.1 - 1.7e-13 49.8 2.2 2.9e-13 49.1 1.5 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EKE39979.1 - 0.0026 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE39979.1 - 0.027 14.6 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHF5 PF03660.9 EKE39980.1 - 3.8e-49 165.2 10.5 4.3e-49 165.0 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 EKE39980.1 - 0.49 7.9 4.2 0.49 7.9 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 EKE39980.1 - 0.51 10.2 12.1 1.6 8.6 1.1 2.4 1 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EKE39980.1 - 1.8 8.3 10.5 19 5.1 6.2 2.2 1 1 1 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.1 EKE39980.1 - 2.4 7.9 14.7 3 7.6 3.5 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EKE39980.1 - 2.9 7.6 9.9 3 7.6 5.6 2.1 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 EKE39980.1 - 5.2 6.8 14.9 2.5 7.8 0.9 3.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE39980.1 - 5.3 6.8 16.5 13 5.6 1.1 3.3 3 1 0 3 3 3 0 zinc-RING finger domain A2L_zn_ribbon PF08792.5 EKE39980.1 - 5.3 6.6 9.7 4 7.0 2.5 2.9 2 0 0 2 2 2 0 A2L zinc ribbon domain RICTOR_M PF14666.1 EKE39981.1 - 2.4e-23 82.3 11.6 4.6e-19 68.3 0.5 3.4 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 EKE39981.1 - 0.0002 21.2 0.0 0.00053 19.8 0.0 1.8 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 OmpH PF03938.9 EKE39981.1 - 0.0058 16.5 3.1 0.0058 16.5 2.1 2.5 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) BUD22 PF09073.5 EKE39981.1 - 3.1 6.7 25.1 2.7 6.9 1.9 2.7 2 0 0 2 2 2 0 BUD22 DUF1498 PF07385.7 EKE39982.1 - 0.0043 16.2 0.1 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1498) TRAM_LAG1_CLN8 PF03798.11 EKE39983.1 - 7.2e-28 97.4 20.4 1e-27 96.9 14.1 1.2 1 0 0 1 1 1 1 TLC domain DUF468 PF04318.7 EKE39983.1 - 0.072 13.6 1.3 0.18 12.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF468) ATP-synt_8 PF00895.15 EKE39983.1 - 0.14 12.3 1.6 30 4.9 0.0 3.2 2 1 0 2 2 2 0 ATP synthase protein 8 CRM1_C PF08767.6 EKE39985.1 - 2.3e-16 59.6 10.1 2.3e-16 59.6 7.0 4.5 4 1 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EKE39985.1 - 3.1e-07 30.4 1.8 3.1e-07 30.4 1.3 3.9 3 1 0 3 3 3 1 Exportin 1-like protein Ipi1_N PF12333.3 EKE39985.1 - 1.2e-05 25.1 0.4 0.011 15.7 0.0 3.3 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation BP28CT PF08146.7 EKE39985.1 - 0.0055 16.4 0.3 0.037 13.7 0.2 2.4 1 1 0 1 1 1 1 BP28CT (NUC211) domain IBN_N PF03810.14 EKE39985.1 - 0.017 15.0 0.1 0.077 12.9 0.0 2.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain RhoGAP PF00620.22 EKE39986.1 - 8.6e-27 93.6 0.9 2.5e-25 88.8 0.1 2.9 2 1 0 2 2 2 1 RhoGAP domain IQ PF00612.22 EKE39986.1 - 0.18 11.5 0.1 0.4 10.4 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif zf-MIZ PF02891.15 EKE39990.1 - 1.8e-13 49.7 9.5 1.8e-13 49.7 6.6 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EKE39990.1 - 0.0097 15.4 4.1 0.0097 15.4 2.8 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit RRM_1 PF00076.17 EKE39991.1 - 1e-45 153.1 3.3 6.9e-12 44.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE39991.1 - 3.9e-36 122.8 0.1 8.4e-11 41.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE39991.1 - 1.3e-12 47.3 5.0 0.0052 16.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EKE39991.1 - 3.7e-08 33.2 1.1 0.11 12.4 0.0 4.5 4 0 0 4 4 4 3 RNA binding domain PARG_cat PF05028.9 EKE39992.1 - 2.5e-45 155.2 7.6 2.5e-45 155.2 5.3 1.8 1 1 1 2 2 2 1 Poly (ADP-ribose) glycohydrolase (PARG) U3_assoc_6 PF08640.6 EKE39993.1 - 2.6e-08 33.5 9.0 2.6e-08 33.5 6.3 3.6 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EKE39993.1 - 0.12 13.0 0.0 41 5.2 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Adaptin_N PF01602.15 EKE39994.1 - 4.4e-81 272.7 21.3 5.4e-81 272.4 14.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EKE39994.1 - 2.3e-11 43.7 0.5 7.5e-06 26.1 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EKE39994.1 - 2.8e-08 33.1 0.3 0.014 15.4 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EKE39994.1 - 3.3e-08 33.5 5.2 5.2e-08 32.9 0.0 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EKE39994.1 - 0.00039 20.2 6.1 0.024 14.5 0.1 4.2 4 1 1 5 5 5 3 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EKE39994.1 - 0.0056 17.1 0.9 0.15 12.6 0.0 3.6 4 1 1 5 5 5 1 HEAT-like repeat Cytochrom_B562 PF07361.6 EKE39994.1 - 0.042 14.2 1.1 0.11 12.8 0.8 1.7 1 0 0 1 1 1 0 Cytochrome b562 NapD PF03927.8 EKE39994.1 - 0.073 12.9 0.1 0.98 9.3 0.0 2.5 2 0 0 2 2 2 0 NapD protein AAA_23 PF13476.1 EKE39994.1 - 1.4 9.1 7.0 0.78 10.0 1.7 2.2 2 0 0 2 2 2 0 AAA domain Erp_C PF06780.6 EKE39994.1 - 2.3 8.0 8.3 0.086 12.6 1.1 2.0 2 0 0 2 2 2 0 Erp protein C-terminus Gpi1 PF05024.10 EKE39995.1 - 1.4e-34 119.4 19.8 1.4e-34 119.4 13.7 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) SpoIIIAH PF12685.2 EKE39996.1 - 0.067 12.6 1.5 0.12 11.8 1.1 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DNA_methylase PF00145.12 EKE39997.1 - 1.7e-30 106.3 1.2 1.8e-28 99.6 0.8 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase RabGAP-TBC PF00566.13 EKE39998.1 - 0.00037 20.0 23.0 0.0014 18.1 10.8 3.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain HTH_39 PF14090.1 EKE39998.1 - 0.022 14.1 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain YppF PF14178.1 EKE39998.1 - 0.057 12.9 0.1 0.16 11.5 0.1 1.8 1 0 0 1 1 1 0 YppF-like protein DUF2129 PF09902.4 EKE39998.1 - 1.9 8.3 5.3 4.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2129) VPS9 PF02204.13 EKE39999.1 - 3.7e-16 59.0 0.7 3.7e-16 59.0 0.5 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain RhoGAP PF00620.22 EKE40000.1 - 6.7e-19 67.9 0.1 2.8e-18 65.9 0.1 2.1 1 0 0 1 1 1 1 RhoGAP domain RVT_N PF13655.1 EKE40000.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.7 4 0 0 4 4 4 0 N-terminal domain of reverse transcriptase SH3_1 PF00018.23 EKE40001.1 - 7.3e-24 82.9 7.3 7.2e-05 22.0 0.0 6.4 6 0 0 6 6 6 5 SH3 domain SH3_9 PF14604.1 EKE40001.1 - 7.2e-20 70.3 8.6 1.6e-07 30.7 0.0 5.4 5 0 0 5 5 5 3 Variant SH3 domain SH3_2 PF07653.12 EKE40001.1 - 8.6e-20 69.9 4.7 1.4e-07 30.8 0.1 5.5 6 0 0 6 6 6 4 Variant SH3 domain SH3_3 PF08239.6 EKE40001.1 - 9.7e-05 22.4 5.9 0.072 13.2 0.1 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_6 PF12913.2 EKE40001.1 - 0.00024 20.2 0.0 0.26 10.5 0.0 3.1 3 0 0 3 3 3 2 SH3 domain of the SH3b1 type BRE PF06113.7 EKE40001.1 - 0.025 13.6 0.1 0.059 12.4 0.0 1.6 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) TFIID_30kDa PF03540.8 EKE40002.1 - 7e-14 51.3 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit PASTA PF03793.14 EKE40002.1 - 0.038 13.6 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 PASTA domain DUF2566 PF10753.4 EKE40003.1 - 0.03 14.2 0.4 0.03 14.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2566) DUF2681 PF10883.3 EKE40003.1 - 0.061 13.5 2.8 0.46 10.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Voltage_CLC PF00654.15 EKE40003.1 - 0.32 9.9 4.3 0.38 9.7 3.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel 7TMR-DISM_7TM PF07695.6 EKE40003.1 - 0.67 9.5 16.5 0.022 14.4 6.5 1.8 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2701 PF10857.3 EKE40003.1 - 1.6 8.5 6.8 0.73 9.6 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2701) DUF4131 PF13567.1 EKE40003.1 - 2.4 7.5 7.6 13 5.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4064 PF13273.1 EKE40003.1 - 4.3 7.5 13.7 8.7 6.5 4.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3290 PF11694.3 EKE40003.1 - 4.3 7.0 10.2 6.3 6.5 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) Pkinase PF00069.20 EKE40004.1 - 5.8e-69 232.1 0.0 6.6e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40004.1 - 2.4e-31 108.7 0.0 4.1e-31 108.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE40004.1 - 0.0009 18.3 0.3 0.0017 17.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKE40004.1 - 0.0041 16.1 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EKE40004.1 - 0.0089 14.8 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 zf-DHHC PF01529.15 EKE40005.1 - 2.1e-21 76.0 19.1 2.1e-21 76.0 13.3 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Auto_anti-p27 PF06677.7 EKE40005.1 - 0.83 9.4 3.9 0.23 11.2 0.4 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Peptidase_S74 PF13884.1 EKE40006.1 - 9.4e-16 57.6 0.1 2.2e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase PSI PF01437.20 EKE40006.1 - 0.22 11.6 11.6 0.47 10.6 8.1 1.5 1 0 0 1 1 1 0 Plexin repeat DUF1900 PF08954.6 EKE40007.1 - 8.7e-21 73.8 0.0 1.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) Angiomotin_C PF12240.3 EKE40007.1 - 0.12 11.8 0.4 0.16 11.4 0.2 1.1 1 0 0 1 1 1 0 Angiomotin C terminal IFP_35_N PF07334.8 EKE40007.1 - 0.14 12.1 2.0 0.27 11.2 1.4 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus WD40 PF00400.27 EKE40008.1 - 2.8e-07 30.1 2.8 0.46 10.4 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Glyco_hydro_18 PF00704.23 EKE40009.1 - 0.0076 15.7 0.4 0.76 9.1 0.0 2.6 2 1 1 3 3 3 2 Glycosyl hydrolases family 18 Creatinase_N PF01321.13 EKE40009.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain DUF187 PF02638.10 EKE40009.1 - 0.087 11.6 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Synapsin_C PF02750.9 EKE40010.1 - 1e-52 178.2 0.1 1.6e-52 177.6 0.1 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 EKE40010.1 - 3.4e-13 49.6 0.0 1.5e-12 47.5 0.0 2.1 2 1 1 3 3 3 1 Synapsin, N-terminal domain AMP-binding PF00501.23 EKE40011.1 - 1.8e-20 72.7 0.0 3.1e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme 2-Hacid_dh PF00389.25 EKE40011.1 - 0.028 13.8 0.0 0.1 12.0 0.0 2.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain RasGAP PF00616.14 EKE40012.1 - 7e-21 74.7 3.3 7e-21 74.7 2.3 2.9 3 2 1 4 4 4 1 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.1 EKE40013.1 - 0.0002 21.1 50.5 4.6 7.6 0.1 15.5 16 1 1 17 17 17 3 Leucine Rich repeat LRR_4 PF12799.2 EKE40013.1 - 0.0055 16.2 45.8 0.07 12.7 0.1 10.4 7 5 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EKE40013.1 - 3.1 8.3 23.1 14 6.4 0.0 9.6 11 1 1 12 12 12 0 Leucine rich repeat DUF3643 PF12356.3 EKE40014.1 - 0.0038 16.5 0.2 0.0082 15.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3643) WD40 PF00400.27 EKE40015.1 - 2.6e-24 84.1 0.1 1.3e-08 34.3 0.4 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Bromodomain PF00439.20 EKE40015.1 - 1.4e-13 50.5 1.5 2.7e-13 49.6 0.2 2.2 2 0 0 2 2 2 1 Bromodomain RAB3GAP2_N PF14655.1 EKE40015.1 - 0.11 11.5 0.3 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ATG22 PF11700.3 EKE40016.1 - 4.7e-05 22.0 0.6 0.00027 19.5 0.0 1.9 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like PRA1 PF03208.14 EKE40016.1 - 6e-05 22.4 1.4 7.9e-05 22.0 0.9 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF1510 PF07423.6 EKE40016.1 - 6.5e-05 22.3 4.2 8.9e-05 21.9 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Folate_carrier PF01770.13 EKE40016.1 - 0.00017 20.2 5.9 0.0002 20.0 0.5 2.0 2 0 0 2 2 2 1 Reduced folate carrier Ycf1 PF05758.7 EKE40016.1 - 0.0012 16.6 0.3 0.0012 16.6 0.2 1.1 1 0 0 1 1 1 1 Ycf1 FPN1 PF06963.7 EKE40016.1 - 0.01 14.2 0.1 0.01 14.2 0.1 1.3 2 0 0 2 2 2 0 Ferroportin1 (FPN1) TMEM51 PF15345.1 EKE40016.1 - 0.01 15.5 2.0 0.014 15.0 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Pex24p PF06398.6 EKE40016.1 - 0.022 13.5 3.3 0.51 9.0 0.1 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Peptidase_S49_N PF08496.5 EKE40016.1 - 0.043 13.6 1.2 0.076 12.8 0.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TRAP_alpha PF03896.11 EKE40016.1 - 0.065 12.2 4.5 0.1 11.5 3.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 EKE40016.1 - 0.15 11.7 8.2 0.24 11.0 5.7 1.4 1 0 0 1 1 1 0 FAM176 family YwiC PF14256.1 EKE40016.1 - 0.94 9.5 4.2 0.23 11.5 0.6 1.6 2 0 0 2 2 2 0 YwiC-like protein DUF4530 PF15039.1 EKE40016.1 - 1.8 8.5 5.8 3.6 7.5 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) SUR7 PF06687.7 EKE40016.1 - 3.9 6.9 10.5 14 5.1 7.3 1.8 1 1 0 1 1 1 0 SUR7/PalI family Tyr_Deacylase PF02580.11 EKE40017.1 - 1.7e-35 122.1 0.0 2.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MFMR PF07777.6 EKE40017.1 - 0.073 12.9 1.8 0.11 12.3 1.3 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR Motile_Sperm PF00635.21 EKE40019.1 - 0.00018 21.1 0.3 0.00043 19.8 0.2 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain RasGEF PF00617.14 EKE40020.1 - 6.6e-25 87.9 0.1 8.7e-25 87.5 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain VSP PF03302.8 EKE40021.1 - 6.8e-08 31.5 26.9 0.00022 20.0 9.4 2.0 1 1 1 2 2 2 2 Giardia variant-specific surface protein C_GCAxxG_C_C PF09719.5 EKE40022.1 - 1.3e-06 28.2 10.0 0.00012 21.8 6.9 2.1 1 1 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) Ribophorin_I PF04597.9 EKE40023.1 - 1.4e-13 50.2 12.9 3e-13 49.0 8.9 1.5 1 1 0 1 1 1 1 Ribophorin I YjcZ PF13990.1 EKE40025.1 - 5.1 6.1 7.1 2 7.4 0.4 3.1 2 1 2 4 4 4 0 YjcZ-like protein Cys_Met_Meta_PP PF01053.15 EKE40026.1 - 1.8e-141 470.8 0.0 2.1e-141 470.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EKE40026.1 - 9.3e-08 31.3 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EKE40026.1 - 1.2e-07 30.7 0.1 3.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EKE40026.1 - 5.9e-05 22.2 0.2 0.00067 18.8 0.1 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EKE40026.1 - 0.00031 20.0 0.0 0.00088 18.5 0.0 1.7 2 1 0 2 2 2 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EKE40026.1 - 0.0013 17.1 0.1 0.0021 16.4 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 EKE40026.1 - 0.044 12.2 0.0 0.07 11.5 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Redoxin PF08534.5 EKE40026.1 - 0.047 13.2 0.1 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 Redoxin Aph-1 PF06105.7 EKE40027.1 - 0.011 15.0 27.3 0.34 10.1 18.9 2.0 1 1 0 1 1 1 0 Aph-1 protein 7TMR-DISM_7TM PF07695.6 EKE40027.1 - 2.7 7.6 28.5 0.91 9.1 5.4 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2244 PF10003.4 EKE40027.1 - 3 7.2 7.6 3.5 6.9 0.3 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) RhoGEF PF00621.15 EKE40030.1 - 1.7e-30 106.2 1.8 2.4e-30 105.7 0.2 2.1 2 0 0 2 2 2 1 RhoGEF domain Epimerase PF01370.16 EKE40031.1 - 8.7e-28 97.3 0.0 1.4e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKE40031.1 - 2.3e-15 56.0 0.2 5.9e-15 54.7 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKE40031.1 - 4.9e-14 52.7 0.0 3.2e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EKE40031.1 - 2.9e-11 42.7 0.0 4.3e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EKE40031.1 - 3.1e-08 32.8 0.0 4.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EKE40031.1 - 0.00063 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EKE40031.1 - 0.00091 18.5 0.6 0.011 15.0 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 EKE40031.1 - 0.06 13.6 0.1 0.22 11.8 0.1 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HMG_box PF00505.14 EKE40032.1 - 2.1e-06 27.8 0.1 2.1e-06 27.8 0.1 3.1 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE40032.1 - 8.5e-06 26.0 0.3 8.5e-06 26.0 0.2 2.6 2 1 0 2 2 2 1 HMG-box domain Apyrase PF06079.6 EKE40033.1 - 8.4e-62 208.9 6.7 9.9e-62 208.7 4.7 1.0 1 0 0 1 1 1 1 Apyrase Zip PF02535.17 EKE40034.1 - 1.6e-17 63.4 0.6 1.6e-17 63.4 0.4 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter DUF1514 PF07438.6 EKE40035.1 - 0.0036 17.1 3.3 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1514) Ninjurin PF04923.7 EKE40035.1 - 0.17 11.6 4.6 0.12 12.1 0.3 2.5 3 0 0 3 3 3 0 Ninjurin SNF2_N PF00176.18 EKE40036.1 - 1.4e-50 171.8 0.5 3.6e-49 167.1 0.1 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE40036.1 - 3.2e-08 33.3 0.0 6.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE40036.1 - 0.00017 21.0 0.0 0.00098 18.6 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase His_Phos_1 PF00300.17 EKE40037.1 - 1.5e-22 80.3 0.0 1.7e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase_Tyr PF07714.12 EKE40038.1 - 1.1e-46 159.0 0.0 1.8e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40038.1 - 1.5e-40 138.9 0.0 3e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 EKE40038.1 - 0.015 15.6 0.2 0.2 12.0 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3481 PF11980.3 EKE40038.1 - 0.041 13.7 0.4 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Clp1 PF06807.9 EKE40039.1 - 3.2e-06 27.0 0.3 5.5e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EKE40039.1 - 8.9e-05 22.2 0.0 0.00027 20.6 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EKE40039.1 - 0.0007 19.3 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase KaiC PF06745.8 EKE40039.1 - 0.0047 16.0 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 EKE40039.1 - 0.0086 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKE40039.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain CobU PF02283.11 EKE40039.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_35 PF14516.1 EKE40039.1 - 0.022 13.3 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EKE40039.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RecA PF00154.16 EKE40039.1 - 0.054 12.5 0.1 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_19 PF13245.1 EKE40039.1 - 0.082 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF2117 PF09890.4 EKE40039.1 - 0.084 12.0 0.9 0.29 10.2 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2117) AAA_17 PF13207.1 EKE40039.1 - 0.089 13.6 0.1 0.24 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 EKE40039.1 - 0.11 11.9 0.1 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 MutS domain V MFS_1 PF07690.11 EKE40040.1 - 2.2e-21 75.9 40.0 1.3e-20 73.4 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EKE40040.1 - 0.045 11.8 7.6 0.013 13.6 0.6 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector UPF0233 PF06781.7 EKE40040.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) SHR3_chaperone PF08229.6 EKE40040.1 - 0.42 9.5 9.7 0.11 11.4 3.0 2.6 2 1 1 3 3 3 0 ER membrane protein SH3 DUF912 PF06024.7 EKE40041.1 - 0.018 15.0 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) P12 PF12669.2 EKE40041.1 - 0.078 13.1 0.8 0.18 12.0 0.5 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family RicinB_lectin_2 PF14200.1 EKE40042.1 - 3.6e-21 75.4 0.6 2.1e-17 63.3 0.1 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EKE40042.1 - 0.0023 17.9 3.2 0.0023 17.9 2.2 1.8 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain SRP54_N PF02881.14 EKE40043.1 - 0.097 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Sec1 PF00995.18 EKE40044.1 - 2.8e-84 283.7 31.3 3.2e-84 283.5 21.7 1.0 1 0 0 1 1 1 1 Sec1 family Latexin PF06907.7 EKE40044.1 - 0.038 13.1 3.1 0.34 10.0 1.8 2.3 1 1 0 1 1 1 0 Latexin Dicistro_VP4 PF11492.3 EKE40044.1 - 0.21 11.6 0.3 5.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Cricket paralysis virus, VP4 Mic1 PF07035.7 EKE40045.1 - 1.1e-13 50.8 0.5 2.8e-13 49.5 0.4 1.7 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like DUF2695 PF10905.3 EKE40045.1 - 0.035 13.8 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) HSP70 PF00012.15 EKE40046.1 - 7.4e-12 43.9 8.5 1.2e-11 43.3 5.9 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE40046.1 - 1.8e-08 33.3 1.0 2.2e-07 29.7 0.7 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Proteasom_Rpn13 PF04683.8 EKE40046.1 - 0.024 14.7 1.4 0.45 10.6 0.3 2.8 2 0 0 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor DEDD_Tnp_IS110 PF01548.12 EKE40046.1 - 0.097 12.3 0.0 4.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Transposase Ras PF00071.17 EKE40047.1 - 2.1e-51 173.5 0.2 2.4e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40047.1 - 6.6e-17 62.1 0.1 1.8e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE40047.1 - 3.9e-08 32.7 0.0 4.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE40047.1 - 4e-06 26.4 0.1 1e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE40047.1 - 3e-05 23.9 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE40047.1 - 0.013 14.7 0.1 0.62 9.3 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B MRVI1 PF05781.7 EKE40047.1 - 0.026 12.9 0.4 0.033 12.5 0.3 1.1 1 0 0 1 1 1 0 MRVI1 protein Gtr1_RagA PF04670.7 EKE40047.1 - 0.052 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PARP PF00644.15 EKE40049.1 - 3.6e-08 33.0 0.1 3.6e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain LRR_4 PF12799.2 EKE40050.1 - 4.5e-52 172.9 72.6 2.2e-08 33.5 2.5 11.7 7 3 5 12 12 12 11 Leucine Rich repeats (2 copies) PP2C PF00481.16 EKE40050.1 - 2.1e-50 171.5 0.0 2.9e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EKE40050.1 - 9.1e-42 140.6 63.4 8.5e-10 38.2 7.5 9.2 5 3 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 EKE40050.1 - 4e-22 74.8 70.8 0.027 14.4 0.7 19.0 18 2 2 20 20 20 9 Leucine Rich Repeat LRR_7 PF13504.1 EKE40050.1 - 6.8e-13 46.5 41.9 1.9 9.0 0.1 15.7 15 3 2 17 17 17 6 Leucine rich repeat PP2C_2 PF13672.1 EKE40050.1 - 9.1e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.1 EKE40050.1 - 2.9e-05 23.7 23.9 0.035 13.6 0.3 5.9 2 2 4 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.1 EKE40050.1 - 0.00017 21.2 54.5 0.41 10.8 0.5 14.7 14 3 1 15 15 15 2 Leucine Rich repeat Asparaginase PF00710.15 EKE40051.1 - 2.6e-103 345.1 0.5 3e-103 344.9 0.3 1.0 1 0 0 1 1 1 1 Asparaginase Gly_reductase PF09338.6 EKE40051.1 - 0.056 11.6 1.3 0.097 10.8 0.9 1.3 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits PP2C PF00481.16 EKE40052.1 - 5.8e-60 202.8 0.0 7.9e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EKE40052.1 - 1.5e-38 130.3 114.0 1.2e-07 31.4 2.2 11.9 3 3 13 16 16 16 15 Leucine rich repeat LRR_4 PF12799.2 EKE40052.1 - 7.2e-38 127.6 126.5 3.6e-06 26.4 3.5 15.0 5 4 12 17 17 17 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EKE40052.1 - 3.1e-13 47.7 117.4 0.083 12.9 0.4 22.9 23 1 1 24 24 24 11 Leucine Rich Repeat LRR_9 PF14580.1 EKE40052.1 - 0.0032 17.0 0.6 0.0032 17.0 0.4 6.5 2 2 5 7 7 7 3 Leucine-rich repeat LRR_7 PF13504.1 EKE40052.1 - 0.02 14.9 96.7 0.23 11.7 0.2 20.7 23 1 0 23 23 23 0 Leucine rich repeat NUDIX PF00293.23 EKE40053.1 - 1.4e-13 50.6 0.1 2.3e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DZR PF12773.2 EKE40053.1 - 0.003 17.3 1.7 0.0073 16.1 1.2 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.6 EKE40053.1 - 0.029 13.8 2.9 0.057 12.9 2.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain IBR PF01485.16 EKE40053.1 - 0.043 13.6 2.4 0.047 13.5 0.7 1.8 1 1 0 1 1 1 0 IBR domain RNA_POL_M_15KD PF02150.11 EKE40053.1 - 0.31 10.7 2.7 13 5.5 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 EKE40053.1 - 8.1 6.2 7.6 0.52 10.0 1.3 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MIG-14_Wnt-bd PF06664.7 EKE40054.1 - 1.2e-07 30.8 34.3 1.2e-07 30.8 23.8 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion ChlI PF13541.1 EKE40054.1 - 0.0091 15.5 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase FAM165 PF14981.1 EKE40054.1 - 0.27 10.7 1.6 0.64 9.5 0.1 2.3 2 0 0 2 2 2 0 FAM165 family RRM_1 PF00076.17 EKE40055.1 - 3.6e-21 74.5 0.5 2.7e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40055.1 - 1.3e-16 60.2 0.1 1.5e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40055.1 - 1.5e-14 53.5 1.3 3.1e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKE40055.1 - 2.1e-05 24.3 1.7 0.05 13.4 0.1 2.5 2 1 0 2 2 2 2 RNA binding motif Latrophilin PF02354.11 EKE40055.1 - 0.074 11.7 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region SMC_N PF02463.14 EKE40056.1 - 5.8e-47 159.7 57.7 1.1e-26 93.5 10.6 5.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKE40056.1 - 4.7e-18 65.3 0.1 1.7e-17 63.4 0.1 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EKE40056.1 - 6.5e-16 59.2 29.2 6.5e-16 59.2 20.3 7.9 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 EKE40056.1 - 4.2e-06 26.1 0.0 8.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EKE40056.1 - 0.00063 19.7 7.5 0.00063 19.7 5.2 6.3 2 2 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EKE40056.1 - 0.007 16.2 0.0 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Kinetocho_Slk19 PF12709.2 EKE40057.1 - 0.0031 17.5 5.0 0.0055 16.7 2.7 1.9 1 1 0 1 1 1 1 Central kinetochore-associated Lge1 PF11488.3 EKE40057.1 - 0.16 12.1 2.1 0.46 10.6 0.3 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 RRM_5 PF13893.1 EKE40058.1 - 9.5e-10 38.1 0.7 2.5e-09 36.8 0.3 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40058.1 - 1.1e-08 34.9 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE40058.1 - 1.2e-07 31.2 0.4 3.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 EKE40058.1 - 7.7 6.5 11.9 0.51 10.3 0.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase_Tyr PF07714.12 EKE40059.1 - 9.3e-28 97.0 0.2 1.8e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40059.1 - 2.4e-27 95.7 0.5 4e-27 94.9 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.1 EKE40059.1 - 6.5e-16 58.3 0.0 1.2e-05 25.6 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE40059.1 - 2.4e-14 53.0 0.0 5.4e-06 26.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE40059.1 - 1.4e-13 50.9 0.0 6.5e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKE40059.1 - 3.1e-08 33.0 0.1 0.017 14.9 0.0 4.4 5 1 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EKE40059.1 - 8.8e-06 25.4 0.1 0.33 11.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat DUF900 PF05990.7 EKE40060.1 - 5.2e-18 65.2 0.0 8.2e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Pkinase_Tyr PF07714.12 EKE40061.1 - 1.9e-39 135.2 0.1 3.3e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40061.1 - 2.6e-37 128.3 0.3 4.9e-37 127.4 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain VSP PF03302.8 EKE40061.1 - 0.004 15.8 240.6 0.045 12.3 29.4 9.2 2 1 7 9 9 9 6 Giardia variant-specific surface protein Kdo PF06293.9 EKE40061.1 - 0.047 12.7 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BatA PF07584.6 EKE40061.1 - 0.083 13.0 0.2 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF2207 PF09972.4 EKE40063.1 - 0.019 13.5 0.7 0.022 13.3 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.7 EKE40063.1 - 0.044 13.8 0.2 0.059 13.4 0.1 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Coagulase PF08764.5 EKE40063.1 - 0.054 13.4 0.9 0.059 13.2 0.6 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase CortBP2 PF09727.4 EKE40063.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 BatD PF13584.1 EKE40063.1 - 0.12 10.9 0.1 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF3753 PF12575.3 EKE40063.1 - 0.54 10.1 3.9 0.1 12.4 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) V_ATPase_I PF01496.14 EKE40067.1 - 2.6e-41 141.3 11.0 3e-41 141.1 7.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family THDPS_N PF14790.1 EKE40067.1 - 0.014 14.9 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal LRR_4 PF12799.2 EKE40068.1 - 1.4e-55 184.1 84.2 1.4e-08 34.1 3.8 13.7 8 3 4 14 14 14 13 Leucine Rich repeats (2 copies) PP2C PF00481.16 EKE40068.1 - 2.5e-55 187.6 0.1 3.6e-55 187.1 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EKE40068.1 - 4.7e-49 163.9 63.5 7.3e-09 35.2 3.0 10.2 3 3 7 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 EKE40068.1 - 2.7e-28 93.6 62.6 0.062 13.3 0.3 20.6 21 0 0 21 21 21 12 Leucine Rich Repeat LRR_7 PF13504.1 EKE40068.1 - 8.6e-16 55.2 46.6 3.4 8.2 0.2 18.8 21 1 0 21 21 21 5 Leucine rich repeat LRR_6 PF13516.1 EKE40068.1 - 2.1e-09 36.4 66.2 0.23 11.6 0.4 16.6 17 2 2 19 19 19 5 Leucine Rich repeat PP2C_2 PF13672.1 EKE40068.1 - 4e-07 29.6 0.0 7.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.1 EKE40068.1 - 0.052 13.1 24.2 0.88 9.1 0.7 5.4 2 2 3 6 6 6 0 Leucine-rich repeat CH PF00307.26 EKE40069.1 - 3.2e-44 149.3 0.0 2.2e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKE40069.1 - 9.8e-15 53.9 0.0 6.7e-10 38.4 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.5 EKE40069.1 - 3.1e-06 27.0 0.1 3.2e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.1 EKE40069.1 - 3.7e-05 23.2 0.4 0.00042 19.9 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EKE40069.1 - 0.00012 21.1 0.3 0.00046 19.2 0.2 2.1 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EKE40069.1 - 0.00026 20.2 0.3 0.00081 18.6 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EKE40069.1 - 0.0022 18.1 0.6 0.0087 16.1 0.4 2.1 1 1 0 1 1 1 1 EF-hand domain pair Spectrin PF00435.16 EKE40069.1 - 0.011 16.0 7.1 0.028 14.7 0.5 3.2 2 1 1 3 3 3 0 Spectrin repeat EF-hand_8 PF13833.1 EKE40069.1 - 0.032 13.8 2.7 0.29 10.7 0.3 3.5 3 1 0 3 3 3 0 EF-hand domain pair DUF3740 PF12548.3 EKE40069.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 Sulfatase protein APG6 PF04111.7 EKE40069.1 - 0.15 11.0 7.3 1.8 7.5 2.7 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 CitMHS PF03600.11 EKE40070.1 - 9.2e-16 57.3 4.3 3e-12 45.8 0.0 2.6 1 1 1 2 2 2 1 Citrate transporter Metallophos PF00149.23 EKE40071.1 - 1.9e-38 131.8 0.5 2.6e-38 131.4 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE40071.1 - 9.2e-06 25.5 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ras PF00071.17 EKE40072.1 - 1.9e-47 160.6 1.3 2.2e-47 160.4 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40072.1 - 6e-15 55.7 0.1 1.1e-14 54.9 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40072.1 - 1.3e-08 34.2 0.2 1.7e-08 33.9 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE40072.1 - 1.1e-05 24.9 0.1 2.8e-05 23.6 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE40072.1 - 0.04 13.8 0.2 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ArsA_ATPase PF02374.10 EKE40072.1 - 0.86 8.5 4.3 0.68 8.9 0.3 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase zf-DHHC PF01529.15 EKE40073.1 - 1.1e-25 89.9 22.4 1.1e-25 89.9 15.5 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase ABC_tran PF00005.22 EKE40074.1 - 2.7e-45 154.0 2.0 2.4e-24 86.1 0.0 3.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EKE40074.1 - 1.5e-19 71.0 12.4 6.5e-06 26.3 4.3 4.6 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EKE40074.1 - 1.8e-07 30.6 10.4 0.0061 15.8 0.0 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EKE40074.1 - 6.4e-06 25.7 0.0 0.0079 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EKE40074.1 - 8.9e-06 25.5 0.2 0.0033 17.3 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EKE40074.1 - 1e-05 26.3 0.1 0.036 14.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKE40074.1 - 5.3e-05 22.4 0.1 0.014 14.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKE40074.1 - 8.5e-05 22.7 0.5 0.12 12.4 0.0 3.6 3 2 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EKE40074.1 - 0.00011 21.7 2.1 0.075 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EKE40074.1 - 0.00059 20.0 0.0 0.063 13.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EKE40074.1 - 0.00063 19.4 0.1 1.5 8.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EKE40074.1 - 0.0019 18.1 0.0 1 9.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EKE40074.1 - 0.0035 17.5 0.3 0.37 10.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EKE40074.1 - 0.0071 16.6 2.1 0.042 14.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EKE40074.1 - 0.0079 16.6 0.4 9.7 6.7 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein AAA_16 PF13191.1 EKE40074.1 - 0.0087 16.0 0.3 1.9 8.4 0.1 2.8 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 EKE40074.1 - 0.016 14.1 0.2 0.34 9.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EKE40074.1 - 0.031 13.6 3.4 1.3 8.4 0.1 2.9 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 EKE40074.1 - 0.039 13.6 1.3 0.4 10.3 0.1 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EKE40074.1 - 0.068 12.5 0.8 12 5.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.1 EKE40074.1 - 0.086 12.7 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EKE40074.1 - 0.12 12.7 0.0 0.12 12.7 0.0 5.1 5 0 0 5 5 5 0 AAA domain AAA_5 PF07728.9 EKE40074.1 - 0.13 11.9 0.4 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EKE40074.1 - 5 6.8 8.3 4.3 7.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 PUF PF00806.14 EKE40075.1 - 6.9e-32 107.1 19.3 3.7e-06 26.0 0.4 8.5 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Dpoe2NT PF12213.3 EKE40075.1 - 0.11 12.4 0.9 1.5 8.7 0.1 3.1 3 1 1 4 4 4 0 DNA polymerases epsilon N terminal Macro PF01661.16 EKE40076.1 - 1.4e-25 89.5 1.0 2.2e-25 88.8 0.1 1.9 2 0 0 2 2 2 1 Macro domain Rhamno_transf PF11316.3 EKE40077.1 - 0.00058 19.1 0.1 0.026 13.7 0.1 2.1 1 1 1 2 2 2 1 Putative rhamnosyl transferase TLD PF07534.11 EKE40077.1 - 0.0058 16.6 5.3 0.011 15.7 3.7 1.5 1 1 0 1 1 1 1 TLD bZIP_1 PF00170.16 EKE40077.1 - 0.0063 16.4 4.0 0.0063 16.4 2.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor UPF0242 PF06785.6 EKE40077.1 - 0.013 14.1 2.7 0.019 13.6 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF2205 PF10224.4 EKE40077.1 - 0.015 14.8 4.9 0.032 13.8 3.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) HALZ PF02183.13 EKE40077.1 - 0.021 14.5 5.9 0.059 13.0 4.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 EKE40077.1 - 0.06 12.8 3.6 0.17 11.3 2.5 1.8 1 0 0 1 1 1 0 Septum formation initiator SUKH-3 PF14433.1 EKE40077.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 SUKH-3 immunity protein VPS11_C PF12451.3 EKE40077.1 - 0.099 12.5 0.4 0.37 10.6 0.3 2.1 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal bZIP_2 PF07716.10 EKE40077.1 - 0.13 12.0 7.0 0.31 10.8 4.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper TALPID3 PF15324.1 EKE40077.1 - 0.28 8.5 2.2 0.31 8.3 1.5 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF904 PF06005.7 EKE40077.1 - 0.45 10.8 11.7 1.2 9.4 8.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) NYD-SP28_assoc PF14775.1 EKE40077.1 - 1.2 8.9 6.1 5.6 6.7 4.3 2.1 1 1 0 1 1 1 0 Sperm tail C-terminal domain Ribosomal_L6e PF01159.14 EKE40077.1 - 3.2 8.0 7.1 5.1 7.3 3.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L6e Tetraspannin PF00335.15 EKE40078.1 - 0.0037 16.5 4.9 0.0044 16.3 3.4 1.1 1 0 0 1 1 1 1 Tetraspanin family UPF0220 PF05255.6 EKE40078.1 - 0.018 14.3 0.9 0.024 13.9 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF2207 PF09972.4 EKE40078.1 - 0.23 10.0 1.3 0.28 9.7 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ISK_Channel PF02060.10 EKE40078.1 - 0.43 10.1 2.6 20 4.7 1.5 2.1 1 1 1 2 2 2 0 Slow voltage-gated potassium channel ESSS PF10183.4 EKE40078.1 - 0.58 10.5 0.0 0.58 10.5 0.0 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BCCT PF02028.12 EKE40078.1 - 0.96 7.6 7.8 1.2 7.3 5.4 1.0 1 0 0 1 1 1 0 BCCT family transporter AMP-binding PF00501.23 EKE40079.1 - 3.4e-72 243.1 0.0 4.7e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKE40079.1 - 1.1e-41 142.4 0.0 2e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 EKE40079.1 - 9.3e-16 58.5 0.0 2.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EKE40079.1 - 1.3e-07 31.3 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EKE40079.1 - 0.00096 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EKE40079.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EKE40079.1 - 0.016 13.9 1.2 0.021 13.5 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EKE40079.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EKE40079.1 - 0.26 11.2 0.0 0.98 9.3 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding MitMem_reg PF13012.1 EKE40079.1 - 0.29 11.2 2.5 1.1 9.4 0.1 3.0 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function zf-C3HC4_3 PF13920.1 EKE40080.1 - 9.5e-05 21.9 14.0 0.00049 19.7 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE40080.1 - 0.0023 17.5 11.4 0.0023 17.5 7.9 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) B-block_TFIIIC PF04182.7 EKE40080.1 - 2.6 7.9 6.3 14 5.5 0.9 3.1 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC FRG1 PF06229.7 EKE40081.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 FRG1-like family RabGAP-TBC PF00566.13 EKE40082.1 - 1.9e-26 92.8 15.9 1.9e-26 92.8 11.0 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EKE40083.1 - 6.4e-42 143.5 0.1 6.4e-42 143.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40083.1 - 1.8e-29 102.6 0.9 7.3e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 EKE40083.1 - 8.9e-23 80.5 1.0 8.9e-23 80.5 0.7 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A Kinase-like PF14531.1 EKE40083.1 - 0.0002 20.4 0.0 0.00046 19.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE40083.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family WW PF00397.21 EKE40084.1 - 0.0012 18.6 1.1 0.0027 17.5 0.8 1.6 1 0 0 1 1 1 1 WW domain Arrestin_N PF00339.24 EKE40084.1 - 0.0038 17.0 0.7 0.019 14.8 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EKE40084.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like K1377 PF15352.1 EKE40084.1 - 0.09 10.7 1.8 0.13 10.1 1.2 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Mannosyl_trans2 PF04188.8 EKE40085.1 - 4.8e-70 236.6 41.9 6e-70 236.3 29.0 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) GDPD PF03009.12 EKE40086.1 - 7.1e-30 104.3 0.0 3.7e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EKE40086.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family RhoGAP PF00620.22 EKE40087.1 - 4.5e-08 32.8 0.2 9.9e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain POR_N PF01855.14 EKE40087.1 - 0.083 12.3 0.0 0.24 10.8 0.0 1.7 1 1 1 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg RhoGAP PF00620.22 EKE40088.1 - 2.1e-10 40.4 0.0 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain EF1G PF00647.14 EKE40088.1 - 0.83 9.3 4.1 2.2 8.0 0.9 2.4 1 1 1 2 2 2 0 Elongation factor 1 gamma, conserved domain C1_1 PF00130.17 EKE40091.1 - 6.8e-05 22.5 6.4 6.8e-05 22.5 4.5 3.3 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EKE40091.1 - 0.0014 18.3 14.7 0.0014 18.3 10.2 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.6 EKE40091.1 - 2.1 8.4 15.7 6.7 6.7 10.9 1.9 1 0 0 1 1 1 0 RING-like domain DUF4206 PF13901.1 EKE40091.1 - 5.7 6.4 24.9 2.9 7.4 6.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4206) Phage_connect_1 PF05135.8 EKE40092.1 - 0.25 11.5 1.8 8 6.6 0.1 2.1 1 1 1 2 2 2 0 Phage gp6-like head-tail connector protein Metallophos PF00149.23 EKE40093.1 - 3.3e-44 150.6 0.3 4.3e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE40093.1 - 0.0002 21.2 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Alpha-amylase PF00128.19 EKE40094.1 - 0.00025 20.5 0.2 0.13 11.6 0.0 2.5 2 1 0 3 3 3 2 Alpha amylase, catalytic domain UQ_con PF00179.21 EKE40095.1 - 2.2e-49 166.4 0.0 2.6e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKE40095.1 - 4.3e-06 26.5 0.0 6.3e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKE40095.1 - 0.071 13.0 0.1 0.097 12.5 0.1 1.6 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EKE40095.1 - 0.094 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 UEV domain Ribosomal_S30 PF04758.9 EKE40096.1 - 2.3e-17 62.4 8.3 2.6e-17 62.2 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Stig1 PF04885.8 EKE40097.1 - 0.06 13.5 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 SopA PF13981.1 EKE40098.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 SopA-like central domain DUF4271 PF14093.1 EKE40100.1 - 0.0025 17.5 4.2 0.0031 17.2 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DUF1282 PF06930.7 EKE40100.1 - 0.0085 15.7 2.6 0.01 15.5 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) TMEM169 PF15052.1 EKE40100.1 - 0.022 14.6 1.6 0.03 14.2 1.1 1.2 1 0 0 1 1 1 0 TMEM169 protein family RAMP4 PF06624.7 EKE40100.1 - 0.042 13.4 1.4 0.18 11.3 0.1 2.2 2 1 0 2 2 2 0 Ribosome associated membrane protein RAMP4 ENTH PF01417.15 EKE40100.1 - 0.097 12.5 0.1 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 ENTH domain DUF4293 PF14126.1 EKE40100.1 - 0.18 11.6 4.7 0.39 10.6 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3112 PF11309.3 EKE40100.1 - 0.22 11.2 4.7 0.43 10.3 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) EI24 PF07264.6 EKE40100.1 - 0.27 10.6 5.9 0.35 10.2 4.1 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PRA1 PF03208.14 EKE40100.1 - 0.55 9.5 4.9 0.82 8.9 3.4 1.2 1 0 0 1 1 1 0 PRA1 family protein Pkinase PF00069.20 EKE40102.1 - 5.7e-64 215.7 0.0 8.6e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40102.1 - 4e-42 144.0 0.0 6.1e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE40102.1 - 5.1e-15 55.5 3.0 5.9e-15 55.3 0.8 2.0 2 1 0 2 2 2 1 PH domain PBD PF00786.23 EKE40102.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH_3 PF14593.1 EKE40102.1 - 3.4e-09 36.5 0.1 9e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EKE40102.1 - 3.1e-06 26.3 0.0 6.8e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EKE40102.1 - 9.9e-06 25.7 4.5 2.4e-05 24.5 1.2 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EKE40102.1 - 0.0085 16.1 0.1 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EKE40103.1 - 1.8e-35 122.4 7.1 4.2e-35 121.2 4.9 1.7 1 0 0 1 1 1 1 RhoGEF domain Laminin_II PF06009.7 EKE40103.1 - 0.077 12.7 1.3 0.45 10.2 0.2 2.3 2 0 0 2 2 2 0 Laminin Domain II zf-CCHC PF00098.18 EKE40104.1 - 8.1e-22 76.0 32.4 2.7e-07 30.1 0.7 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EKE40104.1 - 1.9e-05 24.0 29.0 0.002 17.5 1.2 4.4 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EKE40104.1 - 0.002 17.7 32.1 0.29 10.8 1.6 4.4 4 0 0 4 4 4 4 Zinc knuckle eIF3g PF12353.3 EKE40104.1 - 0.049 13.5 0.6 0.049 13.5 0.4 4.4 3 1 2 5 5 5 0 Eukaryotic translation initiation factor 3 subunit G SNF2_N PF00176.18 EKE40105.1 - 6e-74 248.5 4.2 6e-74 248.5 2.9 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EKE40105.1 - 8.6e-20 70.1 6.1 1.7e-11 43.6 2.0 3.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EKE40105.1 - 1.8e-15 56.5 0.0 4.6e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE40105.1 - 1.2e-06 28.0 0.0 4.6e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4208 PF13907.1 EKE40105.1 - 1.5e-06 28.3 5.8 1.5e-06 28.3 4.0 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) LSM PF01423.17 EKE40106.1 - 6.9e-15 54.3 0.4 9e-15 53.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain FNIP PF05725.7 EKE40107.1 - 0.11 12.4 6.4 0.82 9.6 0.4 4.1 2 1 1 3 3 3 0 FNIP Repeat LRR_8 PF13855.1 EKE40107.1 - 0.57 9.9 20.7 0.59 9.9 0.6 4.9 5 0 0 5 5 5 0 Leucine rich repeat Pkinase PF00069.20 EKE40108.1 - 5.6e-49 166.6 0.2 9.6e-49 165.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40108.1 - 3e-42 144.4 0.2 4.7e-41 140.5 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.19 EKE40108.1 - 3.1e-08 33.2 0.1 8.6e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.1 EKE40108.1 - 0.013 14.5 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EKE40108.1 - 0.085 12.5 0.1 0.22 11.1 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.22 EKE40110.1 - 8.7e-15 54.6 2.0 1.7e-14 53.7 0.1 2.4 2 1 0 2 2 2 1 RhoGAP domain PAH PF02671.16 EKE40110.1 - 0.0022 17.5 0.3 0.082 12.5 0.0 2.9 2 0 0 2 2 2 1 Paired amphipathic helix repeat bZIP_1 PF00170.16 EKE40110.1 - 0.21 11.5 4.7 6.5 6.7 0.2 3.2 3 0 0 3 3 3 0 bZIP transcription factor Antigen_Bd37 PF11641.3 EKE40110.1 - 4.7 6.4 10.4 6.9 5.8 1.2 3.3 3 1 0 3 3 3 0 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF1664 PF07889.7 EKE40110.1 - 9.4 6.0 9.1 2.7 7.8 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DEAD PF00270.24 EKE40111.1 - 1.1e-22 80.2 0.0 2.2e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Arch_ATPase PF01637.13 EKE40111.1 - 0.0069 16.1 1.0 0.013 15.1 0.0 2.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 EKE40111.1 - 0.13 12.0 0.0 0.67 9.7 0.0 2.1 2 1 0 2 2 2 0 Part of AAA domain Sec63 PF02889.11 EKE40113.1 - 2.9e-24 85.8 0.2 2.9e-24 85.8 0.1 2.5 1 1 0 2 2 2 1 Sec63 Brl domain Mitofilin PF09731.4 EKE40113.1 - 0.024 13.3 10.0 0.018 13.7 5.9 1.4 2 0 0 2 2 2 0 Mitochondrial inner membrane protein RicinB_lectin_2 PF14200.1 EKE40114.1 - 2e-13 50.6 0.0 4.3e-11 43.1 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EKE40114.1 - 3.1e-11 43.3 0.0 4.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain VPS9 PF02204.13 EKE40115.1 - 2.7e-08 33.7 0.9 2.7e-08 33.7 0.7 2.8 2 1 1 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain DUF2313 PF10076.4 EKE40115.1 - 0.036 13.4 1.4 0.49 9.7 0.1 3.1 3 1 1 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2313) DUF2095 PF09868.4 EKE40115.1 - 1.4 8.6 5.0 0.53 10.0 0.7 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) RhoGEF PF00621.15 EKE40117.1 - 2.3e-25 89.5 7.8 9e-25 87.5 5.4 2.1 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EKE40117.1 - 0.0034 17.5 0.2 0.093 12.9 0.0 3.3 2 1 0 2 2 2 1 PH domain NUC153 PF08159.7 EKE40118.1 - 1.1e-09 37.6 0.8 1.1e-09 37.6 0.6 4.6 5 0 0 5 5 5 1 NUC153 domain Metallophos PF00149.23 EKE40119.1 - 2.5e-41 141.2 1.0 3e-41 141.0 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L33 PF00471.15 EKE40120.1 - 0.011 15.9 0.9 0.026 14.7 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein L33 RecO_C PF02565.10 EKE40120.1 - 0.015 15.1 0.1 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Recombination protein O C terminal tRNA-synt_1c_C PF03950.13 EKE40121.1 - 0.0016 18.1 0.2 0.003 17.2 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_S7e PF01251.13 EKE40121.1 - 0.068 12.6 0.4 11 5.4 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S7e Peptidase_C48 PF02902.14 EKE40122.1 - 1.5e-22 80.3 8.7 1.5e-22 80.3 6.0 2.3 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain NUDIX PF00293.23 EKE40123.1 - 1.4e-12 47.4 0.0 3.1e-12 46.2 0.0 1.5 1 1 1 2 2 2 1 NUDIX domain S4_2 PF13275.1 EKE40124.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain BLOC1_2 PF10046.4 EKE40125.1 - 4.6e-13 49.1 6.7 5.8e-13 48.8 4.7 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 EKE40125.1 - 0.0027 18.0 2.0 0.0027 18.0 1.4 1.9 1 1 1 2 2 2 1 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EKE40125.1 - 0.0071 16.5 3.3 0.028 14.6 0.3 2.4 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Mannitol_dh PF01232.18 EKE40125.1 - 0.0082 16.0 2.4 0.01 15.7 1.7 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain MCPsignal PF00015.16 EKE40125.1 - 0.0085 15.6 3.6 0.011 15.2 2.5 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 EKE40125.1 - 0.011 15.5 2.8 0.011 15.5 2.0 1.9 1 1 1 2 2 2 0 Laminin Domain II PMC2NT PF08066.7 EKE40125.1 - 0.016 15.4 1.8 0.053 13.8 0.3 2.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF725 PF05267.7 EKE40125.1 - 0.026 14.4 1.4 0.036 13.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF725) Noelin-1 PF12308.3 EKE40125.1 - 0.027 14.2 2.5 0.11 12.2 0.3 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF1664 PF07889.7 EKE40125.1 - 0.032 14.0 4.1 0.026 14.2 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EKE40125.1 - 0.035 13.3 1.8 0.064 12.4 0.2 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EKE40125.1 - 0.042 13.9 6.2 0.075 13.1 4.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RPW8 PF05659.6 EKE40125.1 - 0.06 12.8 1.7 0.5 9.8 0.1 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prefoldin_2 PF01920.15 EKE40125.1 - 0.09 12.5 0.4 0.09 12.5 0.3 2.8 1 1 1 2 2 2 0 Prefoldin subunit DASH_Dad2 PF08654.5 EKE40125.1 - 0.092 12.7 1.4 0.2 11.6 0.2 2.0 1 1 1 2 2 2 0 DASH complex subunit Dad2 S-AdoMet_synt_M PF02772.11 EKE40125.1 - 0.098 12.5 0.3 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain Trehalase PF01204.13 EKE40125.1 - 0.1 11.2 2.8 0.11 11.0 1.9 1.0 1 0 0 1 1 1 0 Trehalase GCOM2 PF15328.1 EKE40125.1 - 0.1 12.2 6.5 0.16 11.6 4.5 1.3 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 SSFA2_C PF14723.1 EKE40125.1 - 0.15 11.7 1.3 5.1 6.7 0.2 2.1 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus CHASE3 PF05227.8 EKE40125.1 - 0.19 11.4 5.0 0.34 10.5 0.4 2.2 1 1 1 2 2 2 0 CHASE3 domain Prominin PF05478.6 EKE40125.1 - 0.19 9.2 7.0 0.21 9.0 4.9 1.0 1 0 0 1 1 1 0 Prominin EFhand_Ca_insen PF08726.5 EKE40125.1 - 0.19 11.7 1.4 0.99 9.4 0.0 2.5 3 0 0 3 3 3 0 Ca2+ insensitive EF hand UPF0184 PF03670.8 EKE40125.1 - 0.19 11.9 1.9 0.23 11.6 0.3 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF3450 PF11932.3 EKE40125.1 - 0.2 10.8 6.5 0.052 12.8 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Complex1_LYR_2 PF13233.1 EKE40125.1 - 0.23 11.9 1.7 0.31 11.5 1.2 1.3 1 0 0 1 1 1 0 Complex1_LYR-like DASH_Dad3 PF08656.5 EKE40125.1 - 0.29 10.8 3.1 0.41 10.3 0.3 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad3 DUF4559 PF15112.1 EKE40125.1 - 0.65 9.1 6.9 0.82 8.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Seryl_tRNA_N PF02403.17 EKE40125.1 - 1 9.4 8.5 0.68 9.9 2.5 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 EKE40125.1 - 2.1 8.1 11.3 2.9 7.7 7.8 1.2 1 0 0 1 1 1 0 Tropomyosin like PPC PF04151.10 EKE40126.1 - 2.6e-07 31.4 14.7 0.0033 18.3 0.1 5.1 5 0 0 5 5 5 2 Bacterial pre-peptidase C-terminal domain DUF3103 PF11301.3 EKE40126.1 - 0.28 9.8 0.0 0.45 9.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) DUF2244 PF10003.4 EKE40126.1 - 0.31 10.3 1.0 1.4 8.2 1.0 1.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) RhoGAP PF00620.22 EKE40127.1 - 3.3e-21 75.4 3.2 5.9e-21 74.6 0.3 2.4 2 0 0 2 2 2 1 RhoGAP domain DNA_repr_REX1B PF14966.1 EKE40127.1 - 0.057 13.7 0.0 0.26 11.6 0.0 2.1 1 0 0 1 1 1 0 DNA repair REX1-B Retrotrans_gag PF03732.12 EKE40127.1 - 0.21 11.6 2.3 4.8 7.3 0.1 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein GlutR_N PF05201.10 EKE40127.1 - 0.27 10.7 2.2 0.36 10.4 0.5 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain Antigen_Bd37 PF11641.3 EKE40128.1 - 0.026 13.8 5.5 0.069 12.4 3.8 1.7 1 1 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein YgaB PF14182.1 EKE40128.1 - 0.5 10.6 5.0 0.51 10.6 0.5 2.8 1 1 2 3 3 3 0 YgaB-like protein RasGEF PF00617.14 EKE40129.1 - 7.3e-08 32.3 4.2 7.3e-08 32.3 2.9 2.0 2 1 0 2 2 2 1 RasGEF domain Tropomyosin PF00261.15 EKE40129.1 - 1.1 8.2 6.4 0.078 12.0 1.2 1.4 2 0 0 2 2 2 0 Tropomyosin Pkinase_Tyr PF07714.12 EKE40130.1 - 3.6e-37 127.8 0.0 6.4e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40130.1 - 1.9e-29 102.6 0.0 4.6e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.1 EKE40130.1 - 1.4e-11 44.0 25.5 1.2e-05 24.9 1.5 5.4 3 1 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 EKE40130.1 - 1.4e-11 43.7 33.0 3.9e-05 23.1 1.7 7.4 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EKE40130.1 - 5.1e-10 37.9 22.6 0.035 14.1 0.7 9.4 8 2 0 8 8 8 4 Leucine Rich Repeat Myotub-related PF06602.9 EKE40130.1 - 9.9e-06 24.5 3.1 0.0091 14.7 0.7 2.6 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain LRR_7 PF13504.1 EKE40130.1 - 3.2e-05 23.4 16.4 1.1 9.8 0.0 7.4 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 EKE40130.1 - 0.017 15.1 29.3 1 9.6 0.6 8.3 8 1 2 10 10 10 0 Leucine Rich repeat Kdo PF06293.9 EKE40130.1 - 0.054 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_box PF00505.14 EKE40132.1 - 3.5e-24 84.8 2.4 4.2e-24 84.5 1.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE40132.1 - 3.4e-12 46.5 2.2 4.5e-12 46.1 1.5 1.2 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EKE40132.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain PRD_Mga PF08270.6 EKE40132.1 - 0.027 13.7 0.7 0.027 13.7 0.5 1.0 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain RE_HaeIII PF09556.5 EKE40132.1 - 0.036 12.9 0.8 0.04 12.7 0.6 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease Imm35 PF15581.1 EKE40132.1 - 0.049 13.6 0.2 0.061 13.3 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 35 Rax2 PF12768.2 EKE40132.1 - 0.072 12.2 0.3 0.078 12.1 0.2 1.0 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FH2 PF02181.18 EKE40134.1 - 1.7e-14 53.5 4.6 1.7e-14 53.5 3.2 4.4 3 2 1 4 4 4 2 Formin Homology 2 Domain IncA PF04156.9 EKE40134.1 - 0.001 18.6 8.2 0.001 18.6 5.7 2.4 2 0 0 2 2 2 1 IncA protein DUF2250 PF10007.4 EKE40134.1 - 0.0041 16.9 0.6 0.023 14.5 0.1 2.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) DUF4407 PF14362.1 EKE40134.1 - 0.19 10.6 6.4 0.31 9.9 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.13 EKE40134.1 - 0.24 11.1 5.4 3 7.6 1.3 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rootletin PF15035.1 EKE40134.1 - 0.57 10.1 15.3 0.17 11.8 7.8 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cep57_CLD_2 PF14197.1 EKE40134.1 - 0.6 10.0 7.5 0.04 13.8 0.7 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Tup_N PF08581.5 EKE40135.1 - 3.1e-05 24.0 11.9 5e-05 23.4 8.2 1.4 1 1 0 1 1 1 1 Tup N-terminal Myosin_tail_1 PF01576.14 EKE40135.1 - 0.0016 16.2 12.2 0.0018 16.0 8.5 1.0 1 0 0 1 1 1 1 Myosin tail DUF3450 PF11932.3 EKE40135.1 - 0.0019 17.5 11.7 0.0049 16.1 7.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Cluap1 PF10234.4 EKE40135.1 - 0.0022 17.2 9.3 0.0029 16.8 6.5 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Filament PF00038.16 EKE40135.1 - 0.0026 17.2 8.1 0.0031 17.0 5.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.3 EKE40135.1 - 0.0028 17.4 11.8 0.0047 16.6 2.6 2.1 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding IFT57 PF10498.4 EKE40135.1 - 0.0033 16.2 11.6 0.0034 16.1 8.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 LXG PF04740.7 EKE40135.1 - 0.0064 16.2 8.6 0.0072 16.1 6.0 1.0 1 0 0 1 1 1 1 LXG domain of WXG superfamily FliD_N PF02465.13 EKE40135.1 - 0.0085 16.4 4.1 0.0093 16.3 1.3 1.9 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 N-terminus AAA_13 PF13166.1 EKE40135.1 - 0.0091 14.5 11.8 0.0098 14.4 8.2 1.0 1 0 0 1 1 1 1 AAA domain SAS4 PF15460.1 EKE40135.1 - 0.0091 15.8 6.8 0.013 15.3 4.7 1.2 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Muted PF14942.1 EKE40135.1 - 0.01 15.7 9.3 0.011 15.5 6.4 1.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein RmuC PF02646.11 EKE40135.1 - 0.01 14.7 5.1 0.013 14.3 3.5 1.2 1 0 0 1 1 1 0 RmuC family EzrA PF06160.7 EKE40135.1 - 0.01 14.0 9.6 0.012 13.7 6.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BicD PF09730.4 EKE40135.1 - 0.011 14.1 7.0 0.012 14.0 4.9 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Tektin PF03148.9 EKE40135.1 - 0.012 14.1 9.9 0.015 13.8 6.9 1.1 1 0 0 1 1 1 0 Tektin family Bacillus_HBL PF05791.6 EKE40135.1 - 0.012 14.9 5.5 0.016 14.5 3.8 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF4404 PF14357.1 EKE40135.1 - 0.015 15.7 4.2 0.023 15.0 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) ERM PF00769.14 EKE40135.1 - 0.015 14.8 12.0 0.016 14.7 8.3 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 EKE40135.1 - 0.015 15.0 5.2 0.024 14.4 3.6 1.3 1 0 0 1 1 1 0 Laminin Domain II BLOC1_2 PF10046.4 EKE40135.1 - 0.016 15.3 9.8 0.032 14.3 6.7 1.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 EKE40135.1 - 0.018 14.8 9.3 0.024 14.5 6.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EKE40135.1 - 0.02 13.4 8.3 0.024 13.1 5.8 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light YlqD PF11068.3 EKE40135.1 - 0.02 14.9 13.1 0.28 11.2 9.1 2.0 1 1 0 1 1 1 0 YlqD protein DUF4618 PF15397.1 EKE40135.1 - 0.021 14.1 9.1 0.18 11.1 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) ADIP PF11559.3 EKE40135.1 - 0.023 14.5 11.4 0.11 12.4 7.8 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding MerR-DNA-bind PF09278.6 EKE40135.1 - 0.024 14.9 5.8 0.03 14.7 0.6 2.2 1 1 1 2 2 2 0 MerR, DNA binding IncA PF04156.9 EKE40135.1 - 0.028 14.0 12.8 0.032 13.8 8.9 1.1 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 EKE40135.1 - 0.029 13.9 9.6 0.037 13.5 6.7 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) EZH2_WD-Binding PF11616.3 EKE40135.1 - 0.032 14.0 0.8 0.032 14.0 0.5 1.8 2 0 0 2 2 1 0 WD repeat binding protein EZH2 ATG16 PF08614.6 EKE40135.1 - 0.033 13.9 11.1 0.041 13.7 7.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Snf7 PF03357.16 EKE40135.1 - 0.034 13.5 2.5 0.034 13.5 1.8 2.0 2 0 0 2 2 2 0 Snf7 ALIX_LYPXL_bnd PF13949.1 EKE40135.1 - 0.037 12.9 7.6 0.046 12.6 5.2 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Fib_alpha PF08702.5 EKE40135.1 - 0.042 13.9 9.6 0.072 13.2 6.7 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EKE40135.1 - 0.042 12.8 11.2 0.047 12.7 7.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 EKE40135.1 - 0.046 11.0 9.1 0.055 10.8 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin PF00804.20 EKE40135.1 - 0.053 13.6 10.4 0.098 12.8 7.2 1.5 1 1 0 1 1 1 0 Syntaxin V-ATPase_C PF03223.10 EKE40135.1 - 0.055 12.3 6.6 0.078 11.8 2.4 1.9 1 1 1 2 2 2 0 V-ATPase subunit C Jnk-SapK_ap_N PF09744.4 EKE40135.1 - 0.06 13.3 9.1 0.074 13.0 6.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HeLo PF14479.1 EKE40135.1 - 0.064 12.9 3.3 0.07 12.8 2.3 1.0 1 0 0 1 1 1 0 Prion-inhibition and propagation TPR_MLP1_2 PF07926.7 EKE40135.1 - 0.066 12.9 13.0 0.13 12.0 9.0 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EKE40135.1 - 0.073 12.2 0.3 0.078 12.1 0.2 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein 4HB_MCP_1 PF12729.2 EKE40135.1 - 0.078 12.3 6.6 0.045 13.1 2.0 1.9 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Occludin_ELL PF07303.8 EKE40135.1 - 0.082 13.6 5.9 2.5 8.8 0.6 2.1 1 1 0 1 1 1 0 Occludin homology domain ECH PF00378.15 EKE40135.1 - 0.1 11.7 1.6 0.11 11.5 1.1 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family DUF812 PF05667.6 EKE40135.1 - 0.1 11.0 9.5 0.17 10.3 6.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 EKE40135.1 - 0.11 10.3 6.2 0.12 10.2 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med28 PF11594.3 EKE40135.1 - 0.11 12.7 4.8 0.13 12.5 3.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 28 ABC_tran_2 PF12848.2 EKE40135.1 - 0.11 12.3 8.8 0.12 12.2 5.4 1.6 1 1 0 1 1 1 0 ABC transporter WXG100 PF06013.7 EKE40135.1 - 0.12 12.4 5.6 0.47 10.4 0.2 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Snapin_Pallidin PF14712.1 EKE40135.1 - 0.12 12.7 7.8 0.17 12.1 5.4 1.3 1 1 0 1 1 1 0 Snapin/Pallidin Baculo_PEP_C PF04513.7 EKE40135.1 - 0.12 12.1 3.5 0.27 11.0 2.4 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus THP2 PF09432.5 EKE40135.1 - 0.14 12.0 4.4 0.17 11.7 3.1 1.1 1 0 0 1 1 1 0 Tho complex subunit THP2 Syntaxin_2 PF14523.1 EKE40135.1 - 0.17 11.9 9.1 0.17 11.9 4.2 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF4200 PF13863.1 EKE40135.1 - 0.18 11.7 14.7 1 9.3 10.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF724 PF05266.9 EKE40135.1 - 0.18 11.3 10.4 0.23 11.0 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PEP-utilisers_N PF05524.8 EKE40135.1 - 0.19 11.5 7.0 1.8 8.3 0.7 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1664 PF07889.7 EKE40135.1 - 0.19 11.5 5.5 0.28 10.9 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LOH1CR12 PF10158.4 EKE40135.1 - 0.2 11.4 5.6 0.87 9.3 3.7 1.8 1 1 0 1 1 1 0 Tumour suppressor protein CENP-Q PF13094.1 EKE40135.1 - 0.23 11.4 11.8 0.94 9.4 8.2 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Uds1 PF15456.1 EKE40135.1 - 0.24 11.3 7.4 0.41 10.6 5.2 1.4 1 1 0 1 1 1 0 Up-regulated During Septation Prefoldin_2 PF01920.15 EKE40135.1 - 0.25 11.1 13.1 0.43 10.3 2.3 2.5 1 1 2 3 3 3 0 Prefoldin subunit Myb_DNA-bind_4 PF13837.1 EKE40135.1 - 0.27 11.4 3.5 0.34 11.0 2.4 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DNA_primase_lrg PF04104.9 EKE40135.1 - 0.27 10.4 4.1 0.3 10.3 2.9 1.0 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DMPK_coil PF08826.5 EKE40135.1 - 0.28 11.1 8.2 0.068 13.0 1.8 2.2 1 1 1 2 2 2 0 DMPK coiled coil domain like CCDC74_C PF14917.1 EKE40135.1 - 0.29 11.1 3.3 0.35 10.9 2.1 1.4 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal Spc7 PF08317.6 EKE40135.1 - 0.3 9.7 11.2 0.35 9.4 7.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EKE40135.1 - 0.33 9.8 9.0 0.44 9.4 6.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 EKE40135.1 - 0.36 10.6 11.3 0.29 10.9 7.0 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 EKE40135.1 - 0.39 10.7 9.6 1.2 9.2 6.7 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 EKE40135.1 - 0.4 10.2 11.7 0.29 10.6 2.9 2.0 1 1 1 2 2 2 0 GrpE Z1 PF10593.4 EKE40135.1 - 0.45 9.6 4.7 0.45 9.6 3.3 1.1 1 0 0 1 1 1 0 Z1 domain HR1 PF02185.11 EKE40135.1 - 0.47 10.2 12.1 1.2e+02 2.5 8.2 2.6 1 1 0 1 1 1 0 Hr1 repeat Cortex-I_coil PF09304.5 EKE40135.1 - 0.47 10.5 11.3 1 9.3 6.6 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil DASH_Spc34 PF08657.5 EKE40135.1 - 0.52 9.9 11.7 0.6 9.7 8.1 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 DivIC PF04977.10 EKE40135.1 - 0.54 9.7 15.4 0.52 9.8 2.3 2.5 1 1 2 3 3 3 0 Septum formation initiator DUF4446 PF14584.1 EKE40135.1 - 0.56 10.0 5.6 0.84 9.4 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) FKBP_N PF01346.13 EKE40135.1 - 0.59 10.1 6.5 4 7.5 4.5 1.9 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Nup54 PF13874.1 EKE40135.1 - 0.61 9.7 9.5 0.39 10.3 3.2 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 BRE1 PF08647.6 EKE40135.1 - 0.61 10.0 9.8 0.8 9.7 6.8 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FadA PF09403.5 EKE40135.1 - 0.65 10.0 8.5 2.1 8.3 5.9 1.8 1 1 0 1 1 1 0 Adhesion protein FadA FlaC_arch PF05377.6 EKE40135.1 - 0.66 9.9 7.4 2.5 8.0 0.2 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cauli_AT PF03233.8 EKE40135.1 - 0.66 9.6 5.1 1.3 8.7 3.5 1.4 1 1 0 1 1 1 0 Aphid transmission protein Mnd1 PF03962.10 EKE40135.1 - 0.69 9.5 10.5 1.1 8.8 7.3 1.4 1 1 0 1 1 1 0 Mnd1 family Macoilin PF09726.4 EKE40135.1 - 0.82 7.8 9.1 0.96 7.6 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein V-SNARE PF05008.10 EKE40135.1 - 0.87 9.7 11.9 32 4.7 8.0 2.1 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus ORF6C PF10552.4 EKE40135.1 - 0.88 9.3 7.1 0.89 9.2 2.8 2.0 1 1 1 2 2 2 0 ORF6C domain Prefoldin PF02996.12 EKE40135.1 - 1.1 8.9 9.3 0.57 9.8 1.7 2.4 1 1 2 3 3 3 0 Prefoldin subunit TMPIT PF07851.8 EKE40135.1 - 1.1 8.2 9.8 1.2 8.1 6.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein CCDC-167 PF15188.1 EKE40135.1 - 1.2 9.1 8.2 3.3 7.7 2.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 HALZ PF02183.13 EKE40135.1 - 1.2 8.8 7.5 2.3 8.0 0.6 2.7 2 1 1 3 3 2 0 Homeobox associated leucine zipper OmpH PF03938.9 EKE40135.1 - 1.3 8.9 11.5 1.6 8.6 8.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.4 EKE40135.1 - 1.3 9.2 5.2 1.9 8.7 3.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF342 PF03961.8 EKE40135.1 - 1.4 7.2 9.5 1.5 7.1 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) eIF-4B PF06273.6 EKE40135.1 - 1.4 7.5 5.1 1.5 7.4 3.6 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Kinetocho_Slk19 PF12709.2 EKE40135.1 - 1.5 8.9 10.7 11 6.1 2.0 2.8 1 1 2 3 3 3 0 Central kinetochore-associated DUF1542 PF07564.6 EKE40135.1 - 1.5 8.8 9.9 1.1e+03 -0.4 6.9 2.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) zf-C4H2 PF10146.4 EKE40135.1 - 1.5 8.7 9.4 1.9 8.4 6.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF972 PF06156.8 EKE40135.1 - 1.7 8.9 8.6 10 6.5 6.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) RPA_interact_M PF14767.1 EKE40135.1 - 1.8 9.3 8.7 2.6 8.8 6.0 1.3 1 1 0 1 1 1 0 Replication protein A interacting middle DUF4164 PF13747.1 EKE40135.1 - 2 8.5 9.3 6.9 6.8 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HAUS6_N PF14661.1 EKE40135.1 - 2.1 7.6 9.7 3.2 7.0 2.3 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF1192 PF06698.6 EKE40135.1 - 2.1 8.2 8.5 20 5.0 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) IFP_35_N PF07334.8 EKE40135.1 - 2.7 8.0 10.2 11 6.0 0.1 2.6 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4298 PF14131.1 EKE40135.1 - 2.9 7.8 6.8 4 7.3 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) Spc24 PF08286.6 EKE40135.1 - 3.1 7.5 10.9 11 5.7 3.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.5 EKE40135.1 - 3.2 7.8 14.6 1.2 9.2 0.3 3.1 1 1 1 3 3 3 0 Osmosensory transporter coiled coil Bap31 PF05529.7 EKE40135.1 - 4.6 6.6 8.7 1.3 8.4 1.8 1.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like XhlA PF10779.4 EKE40135.1 - 5 7.1 10.2 24 4.9 7.1 2.0 1 1 0 1 1 1 0 Haemolysin XhlA DUF4140 PF13600.1 EKE40135.1 - 5.2 7.5 8.7 2.3e+02 2.2 6.0 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1843 PF08898.5 EKE40135.1 - 5.8 7.0 10.9 7.6 6.6 0.9 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF1843) AAA_23 PF13476.1 EKE40135.1 - 6.3 7.0 11.6 8.8 6.5 8.1 1.2 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.1 EKE40135.1 - 8 5.3 8.3 15 4.4 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rho_Binding PF08912.6 EKE40135.1 - 8.9 6.6 11.6 4 7.8 4.3 2.1 1 1 1 2 2 2 0 Rho Binding WD40 PF00400.27 EKE40139.1 - 1.5e-10 40.5 0.2 0.00013 21.6 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Sec16_C PF12931.2 EKE40139.1 - 1.4e-09 38.1 4.0 2.9e-08 33.7 2.8 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 EKE40139.1 - 0.0024 17.3 0.1 1.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.1 EKE40141.1 - 0.00069 19.2 12.9 0.0014 18.3 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain XRN_N PF03159.13 EKE40141.1 - 0.0048 16.3 0.2 0.0064 15.9 0.1 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-Mss51 PF13824.1 EKE40141.1 - 0.025 14.4 2.5 0.051 13.4 1.7 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.1 EKE40141.1 - 0.046 13.2 1.9 0.96 9.0 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain MAT1 PF06391.8 EKE40141.1 - 0.067 12.7 9.5 0.14 11.7 6.5 1.7 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 zf-HIT PF04438.11 EKE40141.1 - 0.07 12.7 0.8 0.07 12.7 0.6 2.0 2 0 0 2 2 2 0 HIT zinc finger Prok-RING_2 PF14445.1 EKE40141.1 - 0.37 10.7 6.4 0.91 9.5 4.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 DZR PF12773.2 EKE40141.1 - 4.1 7.3 10.8 25 4.7 7.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4 PF00097.20 EKE40141.1 - 8.6 6.1 14.7 23 4.7 10.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_pol_Rpb5_N PF03871.9 EKE40142.1 - 0.13 12.6 0.4 0.38 11.1 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain DUF2365 PF10157.4 EKE40143.1 - 8.2e-06 25.7 0.1 8.5e-06 25.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) T4SS PF07996.6 EKE40143.1 - 0.031 14.1 0.1 0.04 13.7 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins HTH_Mga PF08280.6 EKE40143.1 - 0.094 12.4 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF604 PF04646.7 EKE40144.1 - 0.072 12.3 0.1 0.072 12.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF604 NAAA-beta PF15508.1 EKE40144.1 - 0.2 12.0 4.0 17 5.8 0.0 4.0 3 1 1 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Hrs_helical PF12210.3 EKE40145.1 - 0.0047 17.1 4.8 0.0047 17.1 3.4 2.5 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate GvpL_GvpF PF06386.6 EKE40145.1 - 0.48 9.9 10.1 1.1 8.8 7.0 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HECT PF00632.20 EKE40147.1 - 2.3e-73 247.1 4.2 2.3e-73 247.1 2.9 3.5 5 0 0 5 5 5 1 HECT-domain (ubiquitin-transferase) Vps26 PF03643.10 EKE40148.1 - 1.6e-44 151.7 0.8 2.1e-44 151.3 0.5 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EKE40148.1 - 0.0095 15.7 0.1 0.027 14.2 0.1 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF2930 PF11152.3 EKE40148.1 - 0.02 14.0 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2930) RasGAP PF00616.14 EKE40149.1 - 8.3e-21 74.5 1.1 8.3e-21 74.5 0.8 2.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF1180 PF06679.7 EKE40150.1 - 0.0049 16.7 0.1 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Podoplanin PF05808.6 EKE40150.1 - 0.0061 16.1 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Podoplanin Pox_A14 PF05767.7 EKE40150.1 - 0.01 15.7 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Syndecan PF01034.15 EKE40150.1 - 0.014 15.0 1.3 0.038 13.6 0.9 1.7 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EKE40150.1 - 0.015 15.7 0.7 0.031 14.6 0.5 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 EKE40150.1 - 0.019 14.4 0.2 0.019 14.4 0.2 2.5 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor DUF4448 PF14610.1 EKE40150.1 - 0.032 13.7 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Plasmodium_Vir PF05795.6 EKE40150.1 - 0.045 12.9 0.5 0.063 12.4 0.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CD34_antigen PF06365.7 EKE40150.1 - 0.05 13.2 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF912 PF06024.7 EKE40150.1 - 0.056 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1312 PF07009.6 EKE40150.1 - 0.14 11.9 3.7 0.26 11.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) Adeno_E3_CR2 PF02439.10 EKE40150.1 - 0.26 10.8 5.4 0.49 9.9 3.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EKE40150.1 - 0.28 10.5 4.5 0.72 9.2 3.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain E1-E2_ATPase PF00122.15 EKE40151.1 - 7.3e-23 80.7 2.5 1.3e-22 79.9 1.7 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKE40151.1 - 1e-14 55.4 0.4 5e-14 53.2 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE40151.1 - 4.1e-12 45.8 0.4 1.7e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EKE40151.1 - 1.2e-10 41.9 0.1 4.4e-10 40.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 EKE40151.1 - 0.0053 15.5 0.1 0.0097 14.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) PAP2 PF01569.16 EKE40152.1 - 8e-22 77.2 5.2 8e-22 77.2 3.6 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF4131 PF13567.1 EKE40152.1 - 0.35 10.2 4.5 0.27 10.6 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ABC2_membrane_5 PF13346.1 EKE40152.1 - 1.4 8.1 18.6 0.026 13.8 3.4 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF4293 PF14126.1 EKE40152.1 - 1.6 8.5 8.1 0.57 10.1 0.2 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4293) RabGAP-TBC PF00566.13 EKE40153.1 - 1.5e-32 112.7 9.6 1.5e-32 112.7 6.6 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4116 PF13475.1 EKE40153.1 - 0.0014 18.1 0.2 0.041 13.3 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) ALIX_LYPXL_bnd PF13949.1 EKE40154.1 - 1.4e-39 135.8 29.0 1.4e-39 135.8 20.1 2.2 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Syntaxin PF00804.20 EKE40154.1 - 0.0028 17.7 7.7 0.0028 17.7 5.3 4.0 2 1 1 3 3 3 2 Syntaxin Rootletin PF15035.1 EKE40154.1 - 0.0049 16.8 5.3 0.0049 16.8 3.7 3.6 2 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion Mod_r PF07200.8 EKE40154.1 - 0.013 15.3 4.6 0.013 15.3 3.2 4.8 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein YppF PF14178.1 EKE40154.1 - 0.025 14.0 0.2 0.08 12.4 0.1 1.8 1 0 0 1 1 1 0 YppF-like protein TPR_11 PF13414.1 EKE40154.1 - 0.068 12.8 1.7 0.35 10.5 0.2 2.3 1 1 1 2 2 2 0 TPR repeat CPT PF07931.7 EKE40155.1 - 0.051 13.1 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Prenyltransf PF01255.14 EKE40155.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase START PF01852.14 EKE40156.1 - 4.9e-15 55.3 0.0 5.8e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE40156.1 - 0.025 14.2 0.1 0.056 13.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) LAGLIDADG_1 PF00961.14 EKE40156.1 - 0.81 10.2 4.1 0.68 10.5 0.9 2.2 2 0 0 2 2 2 0 LAGLIDADG endonuclease TLD PF07534.11 EKE40157.1 - 1.2e-07 31.7 1.8 1.8e-07 31.2 1.2 1.2 1 0 0 1 1 1 1 TLD AF0941-like PF14591.1 EKE40157.1 - 0.0044 17.0 1.5 0.051 13.6 0.4 2.4 2 0 0 2 2 2 1 AF0941-like FlaC_arch PF05377.6 EKE40157.1 - 0.016 15.0 1.8 0.032 14.1 1.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Rxt3 PF08642.5 EKE40157.1 - 0.02 15.1 0.2 0.088 13.0 0.0 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Prefoldin_2 PF01920.15 EKE40157.1 - 0.085 12.6 1.0 0.16 11.7 0.7 1.5 1 0 0 1 1 1 0 Prefoldin subunit Dynamin_N PF00350.18 EKE40158.1 - 9.7e-36 123.1 0.0 9.7e-36 123.1 0.0 3.3 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EKE40158.1 - 7.3e-06 25.9 0.1 5e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EKE40158.1 - 0.0036 17.7 1.0 0.016 15.6 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein WSN PF02206.13 EKE40158.1 - 1.4 8.7 5.5 0.49 10.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF3523 PF12037.3 EKE40159.1 - 0.012 14.5 3.4 0.017 14.1 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Z1 PF10593.4 EKE40159.1 - 4.1 6.5 8.1 1.9 7.6 3.4 1.8 1 1 1 2 2 2 0 Z1 domain UXS1_N PF11803.3 EKE40160.1 - 0.097 12.4 0.8 11 5.8 0.1 2.4 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal SET PF00856.23 EKE40161.1 - 2.2e-11 44.3 0.2 2.4e-10 40.9 0.0 2.5 2 1 0 2 2 2 1 SET domain DUF1679 PF07914.6 EKE40161.1 - 0.058 12.0 0.8 0.098 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) LIM PF00412.17 EKE40163.1 - 1.3e-20 73.1 19.8 1.5e-11 44.1 3.2 2.4 2 1 0 2 2 2 2 LIM domain zf-dskA_traR PF01258.12 EKE40163.1 - 0.00013 21.6 21.9 0.00047 19.8 0.2 4.3 2 1 2 4 4 4 2 Prokaryotic dksA/traR C4-type zinc finger Zn_Tnp_IS1595 PF12760.2 EKE40163.1 - 0.0074 16.0 2.1 0.0074 16.0 1.5 3.7 2 1 2 4 4 4 2 Transposase zinc-ribbon domain Rad50_zn_hook PF04423.9 EKE40163.1 - 0.014 14.8 0.1 0.014 14.8 0.1 3.3 4 0 0 4 4 4 0 Rad50 zinc hook motif DUF3725 PF12523.3 EKE40163.1 - 0.81 9.8 4.3 0.96 9.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3725) Dynactin_p62 PF05502.8 EKE40163.1 - 1.6 7.3 14.2 10 4.7 10.0 1.9 1 1 0 1 1 1 0 Dynactin p62 family zf-FPG_IleRS PF06827.9 EKE40163.1 - 2.8 7.6 15.9 1.9 8.2 0.1 5.0 5 1 0 5 5 5 0 Zinc finger found in FPG and IleRS Auto_anti-p27 PF06677.7 EKE40163.1 - 3.9 7.3 28.5 0.89 9.3 3.4 4.6 3 2 1 4 4 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Desulfoferrod_N PF06397.7 EKE40163.1 - 4.4 6.7 17.6 0.67 9.3 0.4 4.0 3 1 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain OrfB_Zn_ribbon PF07282.6 EKE40163.1 - 4.6 6.9 14.9 5.4 6.7 3.1 2.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-CHC2 PF01807.15 EKE40163.1 - 8.2 6.0 12.2 5.4 6.6 0.1 2.6 1 1 2 3 3 3 0 CHC2 zinc finger 7TMR-HDED PF07697.6 EKE40164.1 - 0.00092 19.0 0.1 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 7TM-HD extracellular FliJ PF02050.11 EKE40164.1 - 0.0073 16.3 0.5 0.036 14.1 0.1 2.0 2 0 0 2 2 2 1 Flagellar FliJ protein THOC7 PF05615.8 EKE40164.1 - 0.038 14.2 1.4 0.055 13.7 0.3 1.6 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4263 PF14082.1 EKE40164.1 - 0.054 13.4 0.1 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) Apolipoprotein PF01442.13 EKE40164.1 - 0.064 12.7 0.2 5.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 EKE40164.1 - 0.11 12.5 0.9 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4455 PF14643.1 EKE40164.1 - 0.15 10.6 2.2 0.27 9.8 0.3 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4455) GvpK PF05121.7 EKE40164.1 - 0.51 10.1 2.4 0.94 9.3 0.1 2.3 2 1 0 2 2 2 0 Gas vesicle protein K DUF1664 PF07889.7 EKE40164.1 - 1.9 8.2 4.4 4.6 7.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) UCH PF00443.24 EKE40165.1 - 6e-24 84.5 15.5 6e-24 84.5 10.7 2.7 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DSPc PF00782.15 EKE40166.1 - 2.8e-29 101.3 0.1 3.9e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE40166.1 - 0.00058 19.2 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EKE40166.1 - 0.027 13.8 0.1 0.048 13.0 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EKE40166.1 - 0.035 14.3 0.0 0.081 13.1 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKE40166.1 - 0.042 13.8 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate MitoNEET_N PF10660.4 EKE40166.1 - 0.087 12.6 0.5 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF2846 PF11008.3 EKE40167.1 - 0.0042 16.9 0.0 2.3 8.0 0.0 4.5 4 1 0 4 4 4 1 Protein of unknown function (DUF2846) Glyco_hydro_2 PF00703.16 EKE40167.1 - 0.12 12.8 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 ATP-synt_C PF00137.16 EKE40168.1 - 9.2e-28 95.9 27.6 3e-17 62.2 5.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DOT1 PF08123.8 EKE40168.1 - 0.095 11.9 0.2 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF2976 PF11190.3 EKE40168.1 - 0.12 11.9 2.4 0.16 11.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) NapE PF06796.6 EKE40168.1 - 2.5 7.4 5.6 4.4 6.6 1.9 2.3 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Pkinase PF00069.20 EKE40169.1 - 1.3e-78 263.7 0.0 2e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40169.1 - 8.5e-35 120.0 0.0 1.4e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKE40169.1 - 2.4e-11 43.5 0.2 6.1e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EKE40169.1 - 1e-05 24.6 0.0 1.7e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKE40169.1 - 0.00073 18.6 0.1 0.0018 17.3 0.1 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKE40169.1 - 0.0049 16.2 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EKE40169.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EKE40170.1 - 2.1e-16 59.0 7.6 0.00039 20.1 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE40170.1 - 0.023 14.4 0.2 0.073 12.8 0.1 1.9 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region HECT PF00632.20 EKE40171.1 - 9.4e-88 294.4 1.1 9.4e-88 294.4 0.7 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF2254 PF10011.4 EKE40173.1 - 0.34 9.3 3.1 0.46 8.8 2.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) RIC1 PF07064.8 EKE40174.1 - 6.5e-07 29.0 0.2 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 RIC1 FUSC-like PF12805.2 EKE40175.1 - 0.042 12.7 0.6 0.066 12.1 0.4 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Mitofilin PF09731.4 EKE40175.1 - 0.5 8.9 6.3 0.82 8.2 4.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FliJ PF02050.11 EKE40175.1 - 0.58 10.2 8.4 0.032 14.2 2.0 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein Ssu72 PF04722.8 EKE40175.1 - 1.1 8.4 8.6 22 4.2 5.5 2.3 1 1 1 2 2 2 0 Ssu72-like protein DUF4373 PF14297.1 EKE40175.1 - 2.8 8.2 9.1 7.9 6.8 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4373) DUF3981 PF13139.1 EKE40176.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) Rad51 PF08423.6 EKE40177.1 - 1.2e-135 450.3 0.4 1.5e-135 450.0 0.2 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EKE40177.1 - 5.9e-16 58.4 0.0 9.1e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EKE40177.1 - 2.8e-10 40.1 0.4 9.3e-10 38.5 0.3 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EKE40177.1 - 3.8e-10 39.3 0.1 5.7e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EKE40177.1 - 1e-07 31.2 0.1 1.8e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 EKE40177.1 - 5.7e-06 26.5 0.1 1.1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain SpoOE-like PF09388.5 EKE40177.1 - 0.0084 15.5 0.1 1.6 8.3 0.0 2.8 2 0 0 2 2 2 1 Spo0E like sporulation regulatory protein DnaB_C PF03796.10 EKE40177.1 - 0.024 13.5 0.1 0.13 11.0 0.1 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain GvpD PF07088.6 EKE40177.1 - 0.038 12.3 0.0 0.058 11.6 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein PAXNEB PF05625.6 EKE40177.1 - 0.066 12.0 0.0 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein CENP-B_dimeris PF09026.5 EKE40177.1 - 3.4 7.9 9.2 6.8 6.9 6.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GWT1 PF06423.7 EKE40178.1 - 2.4e-14 53.5 3.5 2.4e-14 53.5 2.4 3.9 3 1 1 4 4 4 1 GWT1 KH_1 PF00013.24 EKE40179.1 - 5.4e-06 25.9 1.3 1.4e-05 24.6 0.9 1.7 1 0 0 1 1 1 1 KH domain Nucleo_LEF-12 PF06256.6 EKE40180.1 - 0.025 14.3 1.4 5.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus LEF-12 protein CLASP_N PF12348.3 EKE40181.1 - 0.015 14.6 9.8 0.59 9.4 2.3 3.1 1 1 0 2 2 2 0 CLASP N terminal DUF592 PF04574.8 EKE40181.1 - 0.022 14.2 3.9 0.025 14.1 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF592) V-ATPase_H_C PF11698.3 EKE40181.1 - 0.094 12.6 9.6 0.42 10.5 0.3 3.6 2 1 1 3 3 3 0 V-ATPase subunit H Lyase_aromatic PF00221.14 EKE40182.1 - 1.5e-17 63.2 0.0 3.1e-17 62.1 0.0 1.4 1 1 0 1 1 1 1 Aromatic amino acid lyase Nsp1_C PF05064.8 EKE40183.1 - 0.069 12.7 0.4 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Nsp1-like C-terminal region GtrA PF04138.9 EKE40184.1 - 0.03 14.2 0.1 0.03 14.2 0.0 2.8 3 1 0 3 3 3 0 GtrA-like protein DUF3816 PF12822.2 EKE40184.1 - 0.38 10.6 14.3 0.55 10.1 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) SecE PF00584.15 EKE40184.1 - 0.53 9.9 5.1 1.1 8.9 0.2 2.8 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4149 PF13664.1 EKE40184.1 - 0.63 10.1 5.1 3.1 7.8 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF4231 PF14015.1 EKE40184.1 - 1 9.3 3.1 5 7.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Chordopox_L2 PF05803.7 EKE40184.1 - 6.6 6.4 9.4 0.23 11.1 0.9 2.5 3 0 0 3 3 3 0 Chordopoxvirus L2 protein CTP_transf_2 PF01467.21 EKE40185.1 - 1.6e-06 28.2 0.0 0.00027 21.0 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase MgsA_C PF12002.3 EKE40186.1 - 1.3e-51 174.6 0.5 3.1e-51 173.3 0.0 1.9 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EKE40186.1 - 8e-17 61.6 0.1 2.1e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKE40186.1 - 2.9e-16 59.2 0.0 1.4e-14 53.7 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EKE40186.1 - 1.6e-06 28.0 0.1 1.6e-06 28.0 0.0 2.9 3 1 1 4 4 3 1 AAA domain Sigma54_activat PF00158.21 EKE40186.1 - 3.2e-06 26.7 0.1 0.00011 21.6 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EKE40186.1 - 1.1e-05 25.1 0.0 2.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKE40186.1 - 1.5e-05 25.1 0.8 0.00051 20.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EKE40186.1 - 0.0015 18.5 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EKE40186.1 - 0.0016 18.0 0.1 0.0049 16.3 0.0 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.16 EKE40186.1 - 0.0019 17.3 0.2 0.62 9.1 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EKE40186.1 - 0.0022 18.0 0.2 0.1 12.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EKE40186.1 - 0.0054 17.5 1.3 0.025 15.4 0.5 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EKE40186.1 - 0.0061 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EKE40186.1 - 0.041 14.0 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EKE40186.1 - 0.056 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EKE40186.1 - 0.071 13.4 0.1 0.071 13.4 0.0 3.2 1 1 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EKE40186.1 - 0.083 11.7 0.1 0.083 11.7 0.0 3.0 3 1 1 4 4 4 0 NB-ARC domain ABC_tran PF00005.22 EKE40186.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.7 2 1 0 2 2 1 0 ABC transporter AAA_11 PF13086.1 EKE40186.1 - 0.94 9.0 9.1 7 6.1 6.3 2.2 1 1 0 1 1 1 0 AAA domain Steroid_dh PF02544.11 EKE40188.1 - 1.7e-29 102.5 6.7 1.7e-29 102.5 4.6 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF778 PF05608.7 EKE40190.1 - 1.1e-25 90.1 0.8 2.3e-23 82.6 0.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.9 EKE40190.1 - 0.062 13.0 0.3 0.086 12.6 0.2 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain Erf4 PF10256.4 EKE40190.1 - 2.6 7.9 6.6 0.41 10.5 0.8 2.2 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family F_bP_aldolase PF01116.15 EKE40191.1 - 1.5e-104 349.1 0.0 1.9e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_M8 PF01457.11 EKE40192.1 - 5.6e-67 226.2 1.8 7.2e-67 225.9 1.2 1.1 1 0 0 1 1 1 1 Leishmanolysin TIG PF01833.19 EKE40192.1 - 0.00013 21.8 0.1 0.00051 19.9 0.1 2.1 1 0 0 1 1 1 1 IPT/TIG domain PCI_Csn8 PF10075.4 EKE40193.1 - 1.1e-15 57.6 1.7 1.3e-15 57.3 1.2 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EKE40193.1 - 2.7e-08 33.6 1.0 3.6e-08 33.2 0.7 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family FTH PF01827.22 EKE40193.1 - 0.56 9.8 5.1 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 FTH domain Bromodomain PF00439.20 EKE40194.1 - 1.5e-17 63.3 1.7 5.7e-17 61.4 0.6 2.4 2 0 0 2 2 2 1 Bromodomain DUF1874 PF08960.5 EKE40194.1 - 8.8 6.1 9.4 2.2 8.0 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1874) CBM_20 PF00686.14 EKE40195.1 - 0.0033 17.0 0.1 0.0078 15.7 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain START PF01852.14 EKE40196.1 - 5.1e-19 68.4 0.1 6.1e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE40196.1 - 0.0041 16.7 3.1 0.039 13.5 2.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Pkinase_Tyr PF07714.12 EKE40197.1 - 1.2e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40197.1 - 9.8e-31 106.8 0.3 1.5e-30 106.2 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain PcfJ PF14284.1 EKE40197.1 - 0.0026 17.2 0.4 0.088 12.2 0.0 2.6 2 0 0 2 2 2 1 PcfJ-like protein Kinase-like PF14531.1 EKE40197.1 - 0.044 12.7 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Topo-VIb_trans PF09239.6 EKE40197.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer Poxvirus PF06227.7 EKE40197.1 - 1.1 8.8 9.1 0.68 9.4 1.4 2.9 3 0 0 3 3 3 0 dsDNA Poxvirus Rhodanese PF00581.15 EKE40198.1 - 3.3e-12 46.7 0.0 4.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain TrkA_C PF02080.16 EKE40199.1 - 3.2e-05 23.4 0.0 5.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-C domain Tho2 PF11262.3 EKE40200.1 - 8e-29 100.6 11.8 8e-29 100.6 8.2 5.4 4 3 1 5 5 5 1 Transcription factor/nuclear export subunit protein 2 CobT PF06213.7 EKE40202.1 - 8.6 5.3 10.9 15 4.6 7.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Patched PF02460.13 EKE40203.1 - 3.1e-74 250.3 31.5 3.1e-74 250.3 21.8 2.7 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.3 EKE40203.1 - 4.6e-48 162.5 3.5 4.6e-48 162.5 2.4 2.8 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation TF_Zn_Ribbon PF08271.7 EKE40204.1 - 0.015 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding TFIIB PF00382.14 EKE40204.1 - 0.025 14.3 0.0 0.88 9.4 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DisA-linker PF10635.4 EKE40204.1 - 0.1 12.0 4.6 0.14 11.6 0.3 2.6 2 1 0 2 2 2 0 DisA bacterial checkpoint controller linker region SET PF00856.23 EKE40205.1 - 4.9e-14 52.9 0.1 9.1e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 SET domain SAF PF08666.7 EKE40205.1 - 0.012 16.0 0.0 6.3 7.2 0.0 2.3 2 0 0 2 2 2 0 SAF domain CH PF00307.26 EKE40205.1 - 0.11 12.5 0.0 1.2 9.2 0.0 2.4 2 1 0 2 2 2 0 Calponin homology (CH) domain HMG_box_2 PF09011.5 EKE40206.1 - 0.002 18.4 1.0 0.35 11.2 0.1 2.5 2 0 0 2 2 2 2 HMG-box domain DUF632 PF04782.7 EKE40206.1 - 0.0038 16.3 0.5 0.0074 15.4 0.1 1.6 1 1 0 2 2 2 1 Protein of unknown function (DUF632) START PF01852.14 EKE40207.1 - 2.5e-10 40.0 0.0 3.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE40207.1 - 0.00068 19.3 0.3 0.003 17.2 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) XRN_N PF03159.13 EKE40208.1 - 1.7e-55 187.9 4.5 2.6e-27 95.7 0.0 2.8 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus Acetyltransf_1 PF00583.19 EKE40209.1 - 3.3e-11 43.0 0.0 4.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE40209.1 - 1.5e-08 34.6 0.1 2.7e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE40209.1 - 0.0075 16.1 0.0 0.0094 15.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE40209.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidinotransf PF02274.12 EKE40209.1 - 0.08 12.0 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase UPF0547 PF10571.4 EKE40210.1 - 3.5e-08 32.9 6.5 2.1e-07 30.4 2.3 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 EKE40210.1 - 3.7e-07 29.1 6.8 7.9e-07 28.0 2.7 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EKE40210.1 - 2.8e-06 26.6 4.6 2.8e-06 26.6 3.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 EKE40210.1 - 7.7e-05 22.4 8.8 0.00025 20.7 6.1 1.8 1 1 0 1 1 1 1 Double zinc ribbon LIM PF00412.17 EKE40210.1 - 0.00028 20.8 1.2 0.00028 20.8 0.8 2.4 2 1 0 2 2 2 1 LIM domain Cript PF10235.4 EKE40210.1 - 0.0016 18.7 9.0 0.027 14.8 3.5 2.4 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zf-dskA_traR PF01258.12 EKE40210.1 - 0.053 13.2 8.5 0.29 10.8 2.7 2.6 3 0 0 3 3 2 0 Prokaryotic dksA/traR C4-type zinc finger Latexin PF06907.7 EKE40210.1 - 0.08 12.1 0.1 0.094 11.8 0.1 1.0 1 0 0 1 1 1 0 Latexin Ribosomal_L32p PF01783.18 EKE40210.1 - 0.095 12.8 2.2 4.7 7.4 0.3 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family FYVE PF01363.16 EKE40210.1 - 0.19 11.6 3.0 1.5 8.7 2.1 2.3 1 1 0 1 1 1 0 FYVE zinc finger DUF329 PF03884.9 EKE40210.1 - 0.29 10.7 6.1 6.7 6.3 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF329) RRN7 PF11781.3 EKE40210.1 - 0.46 10.0 9.9 0.12 11.8 3.3 2.4 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-DHHC PF01529.15 EKE40210.1 - 0.51 9.7 2.5 0.49 9.7 1.3 1.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase OrfB_Zn_ribbon PF07282.6 EKE40210.1 - 0.51 10.0 6.5 0.53 9.9 1.2 2.3 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-B_box PF00643.19 EKE40210.1 - 0.59 10.0 3.4 2.1 8.3 1.1 2.3 2 0 0 2 2 2 0 B-box zinc finger zinc-ribbons_6 PF07191.7 EKE40210.1 - 0.62 9.8 6.2 0.12 12.1 1.0 2.0 2 1 0 2 2 2 0 zinc-ribbons zf-Sec23_Sec24 PF04810.10 EKE40210.1 - 0.77 9.3 0.1 0.77 9.3 0.0 2.7 3 1 0 4 4 4 0 Sec23/Sec24 zinc finger zf-NADH-PPase PF09297.6 EKE40210.1 - 0.79 9.2 6.6 5 6.7 0.1 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.5 EKE40210.1 - 1.2 8.7 6.0 8 6.0 2.1 2.7 2 1 0 2 2 2 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.8 EKE40210.1 - 1.8 8.0 6.4 27 4.3 2.1 2.9 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 EKE40210.1 - 3.2 7.7 10.0 3.5 7.6 0.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DUF2175 PF09943.4 EKE40210.1 - 3.2 7.8 10.7 0.17 11.9 1.6 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Prok-RING_1 PF14446.1 EKE40210.1 - 3.2 7.5 9.4 1.9 8.2 1.2 2.5 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EKE40210.1 - 3.7 7.3 9.8 14 5.4 0.8 3.0 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.7 EKE40210.1 - 4.3 6.7 10.6 0.99 8.7 4.1 2.3 2 1 0 2 2 2 0 TFIIB zinc-binding zf-HYPF PF07503.7 EKE40210.1 - 4.6 6.7 7.2 5.4 6.5 0.3 2.9 3 0 0 3 3 3 0 HypF finger YhfH PF14149.1 EKE40210.1 - 4.9 7.0 9.8 31 4.4 1.2 3.2 2 1 1 3 3 3 0 YhfH-like protein TfuA PF07812.7 EKE40212.1 - 0.47 9.9 4.0 0.49 9.8 0.0 2.5 2 1 0 3 3 3 0 TfuA-like protein NUFIP1 PF10453.4 EKE40213.1 - 3.1e-08 32.9 11.5 3.1e-08 32.9 7.9 3.5 1 1 2 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) CopC PF04234.7 EKE40213.1 - 0.052 14.1 0.8 0.078 13.6 0.5 1.2 1 0 0 1 1 1 0 CopC domain Borrelia_P83 PF05262.6 EKE40213.1 - 3.2 5.9 22.4 3.3 5.8 15.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Rotamase_2 PF13145.1 EKE40213.1 - 3.5 8.2 17.2 1.1e+02 3.4 11.9 2.1 1 1 0 1 1 1 0 PPIC-type PPIASE domain DDHD PF02862.12 EKE40213.1 - 3.6 7.3 9.7 4.4 7.0 6.7 1.2 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 EKE40213.1 - 3.8 6.8 22.6 5.1 6.4 15.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PEX11 PF05648.9 EKE40213.1 - 4.1 6.6 10.5 0.061 12.5 1.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Daxx PF03344.10 EKE40213.1 - 4.5 5.6 21.2 5.6 5.3 14.7 1.0 1 0 0 1 1 1 0 Daxx Family Ndc1_Nup PF09531.5 EKE40213.1 - 5 5.4 7.5 5.1 5.4 5.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop53 PF07767.6 EKE40213.1 - 7.5 5.4 30.9 8.7 5.2 21.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Inhibitor_I29 PF08246.7 EKE40216.1 - 0.34 11.2 6.9 0.19 11.9 2.5 2.4 2 1 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) zf-B_box PF00643.19 EKE40218.1 - 0.0001 22.1 44.6 0.0058 16.4 6.7 3.5 3 0 0 3 3 3 3 B-box zinc finger C1_2 PF03107.11 EKE40218.1 - 0.00026 21.0 8.2 0.00026 21.0 5.7 3.8 3 1 0 3 3 3 1 C1 domain zf-UBR PF02207.15 EKE40218.1 - 0.00091 18.8 16.4 0.00091 18.8 11.3 3.6 2 1 1 3 3 3 1 Putative zinc finger in N-recognin (UBR box) C1_3 PF07649.7 EKE40218.1 - 0.0056 16.6 9.5 0.0056 16.6 6.6 3.7 3 1 0 3 3 3 1 C1-like domain zf-UDP PF14569.1 EKE40218.1 - 0.019 14.7 0.8 0.019 14.7 0.6 3.3 3 0 0 3 3 3 0 Zinc-binding RING-finger Peptidase_M43 PF05572.8 EKE40218.1 - 0.3 10.6 3.9 0.44 10.1 2.7 1.2 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A FYVE PF01363.16 EKE40218.1 - 1.4 8.8 38.4 0.26 11.2 4.3 3.3 2 1 1 3 3 3 0 FYVE zinc finger C1_1 PF00130.17 EKE40218.1 - 3.1 7.5 49.5 0.98 9.2 7.7 4.4 3 2 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.16 EKE40218.1 - 4.3 7.2 44.0 0.035 13.9 5.2 3.6 1 1 2 3 3 3 0 IBR domain IF-2B PF01008.12 EKE40220.1 - 2.2e-46 158.0 0.9 2.1e-45 154.9 0.6 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family SpoU_sub_bind PF08032.7 EKE40220.1 - 0.014 15.5 0.1 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding XOO_2897-deam PF14440.1 EKE40220.1 - 0.027 14.1 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Snapin_Pallidin PF14712.1 EKE40220.1 - 0.68 10.2 4.4 0.85 9.9 0.5 2.5 3 0 0 3 3 3 0 Snapin/Pallidin GAGA_bind PF06217.7 EKE40221.1 - 0.14 12.0 8.9 0.18 11.7 6.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 EKE40221.1 - 5.1 6.2 17.0 6.9 5.8 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) La PF05383.12 EKE40222.1 - 5.7e-17 61.2 0.7 1.6e-16 59.8 0.2 2.1 2 0 0 2 2 2 1 La domain RRM_6 PF14259.1 EKE40222.1 - 2.4e-07 30.6 0.3 1.5e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE40222.1 - 2.8e-07 30.0 4.6 3.2e-05 23.4 0.3 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40222.1 - 0.0013 18.4 1.0 0.091 12.6 0.1 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VASP_tetra PF08776.6 EKE40222.1 - 0.0036 16.5 4.1 0.032 13.5 0.2 3.4 3 0 0 3 3 3 1 VASP tetramerisation domain UNC-79 PF14776.1 EKE40222.1 - 1.9 6.7 6.7 3.6 5.8 4.6 1.5 1 1 0 1 1 1 0 Cation-channel complex subunit UNC-79 Thioredoxin PF00085.15 EKE40223.1 - 7.6e-26 89.8 0.1 8.9e-26 89.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKE40223.1 - 0.00037 20.5 0.1 0.00053 20.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EKE40223.1 - 0.0039 17.3 0.2 0.098 12.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain IBD PF10416.4 EKE40223.1 - 0.01 15.6 0.1 0.02 14.6 0.0 1.5 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD Phosducin PF02114.11 EKE40223.1 - 0.014 14.1 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.1 EKE40223.1 - 0.041 13.4 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 EKE40223.1 - 0.078 13.0 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like SRF-TF PF00319.13 EKE40223.1 - 0.081 12.1 0.0 0.17 11.1 0.0 1.6 1 1 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Imm18 PF15566.1 EKE40224.1 - 0.029 13.6 0.2 0.28 10.5 0.0 2.7 2 0 0 2 2 2 0 Immunity protein 18 TLD PF07534.11 EKE40225.1 - 0.33 10.9 3.3 0.41 10.6 2.3 1.2 1 0 0 1 1 1 0 TLD ASF1_hist_chap PF04729.8 EKE40226.1 - 4.1e-39 133.6 0.1 6.4e-39 133.0 0.1 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF3924 PF13062.1 EKE40227.1 - 0.12 12.2 0.9 17 5.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) GTP_EFTU PF00009.22 EKE40228.1 - 4.2e-31 107.8 0.0 4.2e-31 107.8 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EKE40228.1 - 6.5e-19 67.8 0.6 2.5e-18 65.9 0.4 2.2 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EKE40228.1 - 6.3e-13 48.6 1.7 9.2e-09 35.3 0.2 3.5 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EKE40228.1 - 1e-07 31.4 0.0 4.7e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EKE40228.1 - 7.7e-06 25.8 0.1 5.8e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE40228.1 - 0.031 14.4 2.4 0.054 13.6 0.0 2.7 3 1 0 3 3 3 0 AAA domain Ribosomal_L22 PF00237.14 EKE40229.1 - 6.3e-32 109.6 0.2 8.5e-32 109.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ornatin PF02088.10 EKE40229.1 - 0.65 9.6 2.5 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Ornatin RRM_1 PF00076.17 EKE40231.1 - 1.5e-14 53.3 0.0 2.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40231.1 - 4.6e-13 48.8 0.0 8e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40231.1 - 1e-11 44.6 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RPA_interact_N PF14766.1 EKE40234.1 - 0.013 14.9 0.8 0.02 14.3 0.6 1.4 1 0 0 1 1 1 0 Replication protein A interacting N-terminal WHEP-TRS PF00458.15 EKE40234.1 - 0.16 11.6 2.9 0.27 10.9 2.0 1.5 1 1 0 1 1 1 0 WHEP-TRS domain B_lectin PF01453.19 EKE40235.1 - 0.064 13.1 0.2 26 4.7 0.0 3.3 3 0 0 3 3 3 0 D-mannose binding lectin Erf4 PF10256.4 EKE40236.1 - 5.8e-06 26.1 0.1 6.6e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Ribosomal_L34e PF01199.13 EKE40237.1 - 8.5e-31 106.0 4.9 8.5e-31 106.0 3.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e CaM-KIIN PF15170.1 EKE40237.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor DUF3133 PF11331.3 EKE40237.1 - 0.14 11.7 3.3 0.32 10.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Lar_restr_allev PF14354.1 EKE40237.1 - 0.19 12.0 1.4 7.8 6.8 1.0 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.8 EKE40237.1 - 1.1 8.8 6.5 2.4 7.7 1.0 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S14 PF00253.16 EKE40238.1 - 1e-17 63.2 4.4 1.1e-17 63.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DZR PF12773.2 EKE40238.1 - 0.14 11.9 1.1 0.21 11.4 0.8 1.3 1 1 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EKE40238.1 - 0.16 12.0 1.9 0.33 11.0 0.2 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase ZZ PF00569.12 EKE40238.1 - 0.55 9.8 3.0 2.9 7.4 2.1 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type Ribosomal_L40e PF01020.12 EKE40238.1 - 0.79 9.3 5.8 3.7 7.2 0.3 2.1 1 1 1 2 2 2 0 Ribosomal L40e family SNARE_assoc PF09335.6 EKE40239.1 - 5.1e-20 71.9 7.4 5.1e-20 71.9 5.1 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein RasGAP PF00616.14 EKE40240.1 - 4.2e-06 26.5 7.3 4.2e-06 26.5 5.1 2.5 1 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Med21 PF11221.3 EKE40240.1 - 1.5 8.7 12.6 0.97 9.4 2.3 2.5 3 0 0 3 3 3 0 Subunit 21 of Mediator complex DMPK_coil PF08826.5 EKE40240.1 - 4.2 7.3 10.5 0.45 10.4 3.2 2.3 2 1 0 2 2 2 0 DMPK coiled coil domain like Rad9 PF04139.8 EKE40241.1 - 1.5e-14 53.7 4.2 1.7e-14 53.5 2.9 1.1 1 0 0 1 1 1 1 Rad9 DASH_Dad2 PF08654.5 EKE40241.1 - 0.065 13.2 0.4 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 XhlA PF10779.4 EKE40241.1 - 0.5 10.3 3.8 0.23 11.4 0.3 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Tubulin PF00091.20 EKE40242.1 - 1.8e-69 233.8 0.1 1.1e-68 231.2 0.0 1.9 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKE40242.1 - 1.5e-38 131.7 0.0 2.2e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EKE40242.1 - 2.4e-06 27.5 0.0 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EKE40242.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Tubulin domain Ank_2 PF12796.2 EKE40243.1 - 8.9e-21 74.0 0.2 1.7e-07 31.4 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE40243.1 - 2.1e-16 58.7 0.2 1.9e-06 27.3 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EKE40243.1 - 5.1e-15 55.5 0.2 9.4e-07 29.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE40243.1 - 7.6e-15 54.6 0.1 1.3e-06 28.4 0.5 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE40243.1 - 1.4e-13 49.6 0.8 0.00053 19.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Patatin PF01734.17 EKE40243.1 - 4.1e-12 46.4 0.0 1.2e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase RhoGEF PF00621.15 EKE40244.1 - 1.1e-11 44.9 13.1 2.1e-11 44.0 4.1 3.0 3 0 0 3 3 3 2 RhoGEF domain Myco_arth_vir_N PF09610.5 EKE40244.1 - 0.02 14.8 0.2 0.072 13.0 0.1 1.9 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF2392 PF10288.4 EKE40245.1 - 0.019 15.2 0.2 0.15 12.3 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) RRN9 PF10680.4 EKE40245.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor DUF373 PF04123.8 EKE40249.1 - 2.6 6.9 7.8 0.2 10.6 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Sec23_trunk PF04811.10 EKE40250.1 - 6.4e-24 84.6 0.5 1.4e-23 83.5 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EKE40250.1 - 2.9e-12 46.9 0.3 2.6e-11 43.8 0.1 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EKE40250.1 - 8.6e-05 21.9 1.9 0.00048 19.5 1.3 2.3 1 1 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EKE40250.1 - 0.0001 21.7 2.7 0.0001 21.7 1.9 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DUF3674 PF12426.3 EKE40250.1 - 0.026 13.9 0.5 0.067 12.5 0.3 1.7 1 0 0 1 1 1 0 RNA dependent RNA polymerase UPF0150 PF03681.10 EKE40251.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) Thioredoxin PF00085.15 EKE40252.1 - 1.8e-28 98.2 0.1 1.9e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKE40252.1 - 2.3e-09 37.2 0.3 2.1e-08 34.1 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EKE40252.1 - 3.5e-07 30.3 0.1 2.8e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EKE40252.1 - 1.7e-06 27.5 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EKE40252.1 - 3.9e-06 26.4 0.1 5.8e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EKE40252.1 - 2.9e-05 23.7 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EKE40252.1 - 0.00022 20.9 0.1 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.1 EKE40252.1 - 0.0035 17.3 0.1 0.0063 16.5 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 EKE40252.1 - 0.11 12.4 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin bZIP_Maf PF03131.12 EKE40253.1 - 1.6e-05 25.1 6.9 2.2e-05 24.6 4.8 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EKE40253.1 - 0.002 18.0 8.7 0.002 18.0 6.0 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EKE40253.1 - 0.0022 17.7 7.6 0.0022 17.7 5.3 1.9 1 1 1 2 2 2 1 Basic region leucine zipper TPR_MLP1_2 PF07926.7 EKE40253.1 - 0.022 14.5 9.5 0.4 10.4 6.2 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3440 PF11922.3 EKE40253.1 - 0.073 12.6 2.3 0.1 12.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) IncA PF04156.9 EKE40253.1 - 0.12 11.9 5.9 0.14 11.7 4.1 1.1 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EKE40253.1 - 0.42 10.4 2.6 0.55 10.0 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CCG PF02754.11 EKE40253.1 - 0.68 9.9 3.1 0.65 10.0 0.8 2.0 1 1 1 2 2 2 0 Cysteine-rich domain Tox-ODYAM1 PF15642.1 EKE40253.1 - 0.86 8.2 7.9 0.95 8.0 5.5 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF342 PF03961.8 EKE40253.1 - 1.2 7.4 11.7 1.4 7.2 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3987 PF13148.1 EKE40253.1 - 1.3 7.4 5.3 1.4 7.4 3.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) DUF724 PF05266.9 EKE40253.1 - 1.6 8.3 10.3 2.3 7.7 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EKE40253.1 - 2 6.1 7.9 2.4 5.9 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 EKE40253.1 - 6 5.8 8.1 8.2 5.3 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein AAA_23 PF13476.1 EKE40253.1 - 7.6 6.8 13.3 9 6.5 9.2 1.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EKE40254.1 - 3e-65 219.9 0.4 4e-65 219.5 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40254.1 - 1.2e-32 113.0 0.2 6.1e-32 110.6 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE40254.1 - 1.7e-08 33.8 0.1 7.2e-07 28.4 0.0 2.7 2 1 0 2 2 2 1 Kinase-like FHA PF00498.21 EKE40254.1 - 8.1e-06 25.8 0.3 1.8e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 FHA domain YrbL-PhoP_reg PF10707.4 EKE40254.1 - 0.002 17.4 1.8 0.23 10.7 0.0 2.5 1 1 1 2 2 2 2 PhoP regulatory network protein YrbL PIP49_C PF12260.3 EKE40254.1 - 0.014 14.8 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 APH PF01636.18 EKE40254.1 - 0.029 14.1 0.0 0.091 12.4 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family tRNA-synt_1g PF09334.6 EKE40255.1 - 2.9e-140 467.3 0.6 3.6e-140 467.0 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EKE40255.1 - 1.4e-12 46.5 3.5 1.5e-05 23.2 0.0 3.4 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EKE40255.1 - 0.0022 17.1 2.4 0.016 14.3 0.0 3.1 3 1 1 4 4 4 1 tRNA synthetases class I (C) catalytic domain FliG_C PF01706.11 EKE40255.1 - 0.047 13.6 0.3 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 FliG C-terminal domain Laminin_EGF PF00053.19 EKE40255.1 - 0.13 12.1 7.7 0.53 10.2 5.4 2.1 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) C1_1 PF00130.17 EKE40255.1 - 8.9 6.1 9.9 2.2 8.0 1.0 2.5 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Filament PF00038.16 EKE40256.1 - 0.0027 17.2 17.7 0.0027 17.2 12.3 1.9 1 1 1 2 2 2 1 Intermediate filament protein DUF3584 PF12128.3 EKE40256.1 - 0.01 13.2 21.5 0.012 12.9 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.17 EKE40256.1 - 0.013 15.5 15.3 0.013 15.5 10.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.1 EKE40256.1 - 0.023 13.8 18.5 0.034 13.3 12.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 His_kinase PF06580.8 EKE40256.1 - 0.029 14.2 4.5 0.029 14.2 3.1 2.1 2 0 0 2 2 2 0 Histidine kinase GAS PF13851.1 EKE40256.1 - 0.032 13.4 26.2 0.099 11.8 11.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EKE40256.1 - 0.064 12.8 22.1 0.18 11.3 4.4 2.0 1 1 1 2 2 2 0 IncA protein PAH PF02671.16 EKE40256.1 - 0.067 12.8 1.3 2.8 7.6 0.2 2.7 2 0 0 2 2 2 0 Paired amphipathic helix repeat Chordopox_A30L PF06015.7 EKE40256.1 - 0.068 12.7 4.7 0.13 11.8 3.3 1.5 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Osmo_CC PF08946.5 EKE40256.1 - 0.085 12.8 11.5 0.47 10.5 4.3 3.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Reo_sigmaC PF04582.7 EKE40256.1 - 0.13 11.4 4.4 0.8 8.8 0.8 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Apt1 PF10351.4 EKE40256.1 - 0.14 11.0 16.9 0.065 12.0 7.9 2.0 1 1 1 2 2 2 0 Golgi-body localisation protein domain TAF8_C PF10406.4 EKE40256.1 - 0.27 11.3 1.9 0.45 10.6 0.2 2.2 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Cytochrom_C_2 PF01322.15 EKE40256.1 - 0.28 11.7 5.7 0.14 12.7 1.2 2.0 1 1 1 2 2 2 0 Cytochrome C' Sec34 PF04136.10 EKE40256.1 - 0.35 10.5 13.2 0.72 9.5 9.2 1.6 1 1 0 1 1 1 0 Sec34-like family Fmp27_WPPW PF10359.4 EKE40256.1 - 0.4 9.0 15.3 0.49 8.7 10.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3166 PF11365.3 EKE40256.1 - 0.6 10.6 9.0 4.5 7.7 2.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Spc7 PF08317.6 EKE40256.1 - 0.63 8.6 21.1 1 7.9 14.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.7 EKE40256.1 - 0.67 8.0 24.1 0.42 8.7 11.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Acetyltransf_11 PF13720.1 EKE40256.1 - 1.1 9.5 4.4 0.75 10.0 0.5 2.4 1 1 2 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GLE1 PF07817.8 EKE40256.1 - 1.2 7.9 13.2 0.27 10.1 6.9 1.6 1 1 1 2 2 2 0 GLE1-like protein FlxA PF14282.1 EKE40256.1 - 1.2 9.0 23.4 1.2 9.1 15.2 1.8 1 1 0 1 1 1 0 FlxA-like protein APG6 PF04111.7 EKE40256.1 - 1.3 8.0 26.2 1.1 8.2 11.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 HALZ PF02183.13 EKE40256.1 - 1.5 8.5 13.4 0.41 10.4 1.9 3.7 2 2 1 3 3 3 0 Homeobox associated leucine zipper DUF4164 PF13747.1 EKE40256.1 - 1.9 8.6 13.0 8 6.6 5.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 EKE40256.1 - 2 6.1 13.8 2.4 5.8 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vac_Fusion PF02346.11 EKE40256.1 - 2.1 7.8 6.6 0.76 9.2 0.5 2.9 2 2 2 4 4 4 0 Chordopoxvirus fusion protein Syntaxin-6_N PF09177.6 EKE40256.1 - 2.3 8.6 12.0 5.2 7.5 6.6 2.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal ADIP PF11559.3 EKE40256.1 - 3.9 7.3 28.2 0.52 10.2 11.6 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EKE40256.1 - 4 7.1 25.5 2.6 7.8 13.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Rotamase PF00639.16 EKE40256.1 - 4.5 8.0 7.8 4.6 8.0 0.7 2.5 1 1 1 2 2 2 0 PPIC-type PPIASE domain Tropomyosin_1 PF12718.2 EKE40256.1 - 4.5 7.1 23.7 4.9 6.9 3.2 2.5 1 1 1 2 2 2 0 Tropomyosin like DUF972 PF06156.8 EKE40256.1 - 5.8 7.3 19.7 6.8 7.0 7.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 EKE40256.1 - 6 6.9 20.7 1.8 8.6 8.7 2.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil Macoilin PF09726.4 EKE40256.1 - 8.7 4.4 16.9 10 4.2 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein PP2C_2 PF13672.1 EKE40257.1 - 5.8e-05 22.5 0.0 9.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE40257.1 - 0.13 11.9 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DnaJ PF00226.26 EKE40259.1 - 5.7e-28 96.4 1.5 5.7e-28 96.4 1.0 2.0 3 0 0 3 3 3 1 DnaJ domain CTDII PF01556.13 EKE40259.1 - 2.6e-17 62.4 2.8 2.2e-16 59.5 0.0 3.1 3 1 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKE40259.1 - 2.6e-13 49.7 19.6 5.1e-13 48.8 13.6 1.5 1 0 0 1 1 1 1 DnaJ central domain FYVE_2 PF02318.11 EKE40259.1 - 0.23 11.3 10.4 0.9 9.4 7.2 1.8 1 1 1 2 2 2 0 FYVE-type zinc finger HypA PF01155.14 EKE40259.1 - 1.6 8.4 10.3 3.7 7.2 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Rap_GAP PF02145.10 EKE40261.1 - 5.2e-13 48.8 5.2 6.7e-12 45.1 3.6 2.5 1 1 0 1 1 1 1 Rap/ran-GAP SOCS_box PF07525.11 EKE40261.1 - 0.015 15.1 0.0 0.062 13.1 0.0 2.1 1 0 0 1 1 1 0 SOCS box Suf PF05843.9 EKE40262.1 - 7.6e-13 48.8 3.1 2.5e-10 40.5 2.2 2.1 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) GCR1_C PF12550.3 EKE40262.1 - 0.099 12.5 1.2 0.39 10.6 0.1 2.3 2 1 0 2 2 2 0 Transcriptional activator of glycolytic enzymes LON PF02190.11 EKE40262.1 - 0.42 10.2 3.9 0.39 10.3 0.5 2.0 2 0 0 2 2 2 0 ATP-dependent protease La (LON) domain Myb_DNA-bind_4 PF13837.1 EKE40263.1 - 0.012 15.7 0.4 0.019 15.0 0.2 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain TetR_C_4 PF08359.6 EKE40263.1 - 0.054 13.4 0.1 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region DUF4131 PF13567.1 EKE40264.1 - 0.26 10.6 8.9 1.5 8.1 6.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2484 PF10658.4 EKE40264.1 - 0.31 11.1 5.9 1.3 9.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) 2TM PF13239.1 EKE40264.1 - 0.92 9.6 12.7 4.6 7.3 3.1 2.4 1 1 1 2 2 2 0 2TM domain Tetraspannin PF00335.15 EKE40264.1 - 1.2 8.3 17.8 3.9 6.6 12.4 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF2417 PF10329.4 EKE40264.1 - 2.3 7.5 8.9 0.11 11.8 1.9 1.8 1 1 1 2 2 2 0 Region of unknown function (DUF2417) Wzy_C PF04932.10 EKE40264.1 - 6 6.6 13.7 0.32 10.7 3.5 2.0 1 1 1 2 2 2 0 O-Antigen ligase Cytochrom_B_C PF00032.12 EKE40264.1 - 7.6 6.8 10.7 1.3 9.3 4.5 1.7 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Corona_M PF01635.13 EKE40264.1 - 7.7 5.3 7.8 0.28 10.1 1.1 1.6 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein DHO_dh PF01180.16 EKE40265.1 - 5.4e-29 101.0 0.1 1.4e-28 99.7 0.1 1.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.1 EKE40265.1 - 1.3e-22 79.4 11.9 1.7e-21 75.9 5.1 3.2 3 0 0 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.1 EKE40265.1 - 2.6e-15 56.0 10.5 2.6e-15 56.0 7.2 3.1 2 1 1 3 3 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 EKE40265.1 - 4.6e-11 43.1 0.0 0.00035 20.7 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.22 EKE40265.1 - 1.8e-09 36.7 19.1 4.1e-08 32.4 2.6 3.3 3 0 0 3 3 2 2 4Fe-4S binding domain Pyr_redox_2 PF07992.9 EKE40265.1 - 1.2e-08 35.0 0.0 4.5e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EKE40265.1 - 4.9e-08 33.2 10.6 4.9e-08 33.2 7.4 3.0 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE40265.1 - 3.3e-07 30.0 10.2 3.3e-07 30.0 7.1 3.0 3 0 0 3 3 2 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 EKE40265.1 - 4.2e-07 30.2 0.3 0.015 15.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKE40265.1 - 8.9e-07 28.8 0.0 4.5e-06 26.5 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_9 PF13187.1 EKE40265.1 - 1.3e-06 28.5 10.2 1.3e-06 28.5 7.1 3.0 2 1 1 3 3 2 1 4Fe-4S dicluster domain Shikimate_DH PF01488.15 EKE40265.1 - 2.7e-06 27.5 1.1 0.027 14.5 0.0 3.7 3 1 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase Fer4_6 PF12837.2 EKE40265.1 - 1.5e-05 24.6 26.8 3.9e-05 23.3 2.3 3.9 3 0 0 3 3 3 2 4Fe-4S binding domain Thi4 PF01946.12 EKE40265.1 - 5.1e-05 22.4 0.0 0.00013 21.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Fer4_2 PF12797.2 EKE40265.1 - 0.00027 20.6 3.1 0.00027 20.6 2.2 3.7 3 0 0 3 3 2 2 4Fe-4S binding domain ELFV_dehydrog PF00208.16 EKE40265.1 - 0.0003 20.4 0.0 0.0085 15.6 0.0 2.4 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Fer4_8 PF13183.1 EKE40265.1 - 0.00038 20.4 9.6 0.00038 20.4 6.7 3.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain NAD_binding_7 PF13241.1 EKE40265.1 - 0.00044 20.4 0.3 0.31 11.3 0.1 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EKE40265.1 - 0.0015 17.4 0.3 0.0051 15.7 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EKE40265.1 - 0.0034 16.9 0.1 0.39 10.2 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EKE40265.1 - 0.0041 16.3 0.1 0.99 8.5 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EKE40265.1 - 0.0058 16.3 0.1 0.11 12.1 0.0 2.6 3 0 0 3 3 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CPSase_L_chain PF00289.17 EKE40265.1 - 0.01 15.9 0.5 0.22 11.6 0.1 2.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HI0933_like PF03486.9 EKE40265.1 - 0.013 13.9 0.1 0.022 13.2 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 EKE40265.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 EKE40265.1 - 0.016 15.6 3.0 7.6 7.0 0.0 3.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Fer4_4 PF12800.2 EKE40265.1 - 0.017 15.4 2.6 0.017 15.4 1.8 4.8 4 0 0 4 4 2 0 4Fe-4S binding domain DAO PF01266.19 EKE40265.1 - 0.019 13.8 0.0 0.05 12.5 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_15 PF13459.1 EKE40265.1 - 0.02 15.4 0.3 0.02 15.4 0.2 3.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain NAD_binding_9 PF13454.1 EKE40265.1 - 0.027 14.2 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKE40265.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 EKE40265.1 - 0.051 13.3 0.0 0.66 9.7 0.0 2.8 4 0 0 4 4 2 0 ThiF family GIDA PF01134.17 EKE40265.1 - 0.086 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_16 PF13484.1 EKE40265.1 - 0.12 13.1 23.1 0.046 14.4 1.3 3.8 2 1 2 4 4 4 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 EKE40265.1 - 0.2 12.0 27.2 0.11 12.7 0.4 3.9 3 1 1 4 4 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.1 EKE40265.1 - 0.4 11.0 17.8 0.08 13.3 2.6 3.4 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EKE40265.1 - 0.96 10.1 32.4 0.042 14.4 4.0 4.4 3 0 0 3 3 3 0 4Fe-4S binding domain Ku PF02735.11 EKE40266.1 - 3e-09 36.5 0.0 5.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA PF00092.23 EKE40266.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Methyltransf_32 PF13679.1 EKE40266.1 - 0.11 12.1 0.3 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA_int_endo_N PF02778.9 EKE40267.1 - 0.049 13.1 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain NUMOD4 PF07463.6 EKE40267.1 - 0.049 13.5 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 NUMOD4 motif PP2C PF00481.16 EKE40268.1 - 4.4e-28 98.3 0.1 7.1e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE40268.1 - 2.3e-07 30.4 0.0 3.8e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Peptidase_M42 PF05343.9 EKE40268.1 - 0.019 13.7 0.5 0.26 10.0 0.1 1.9 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase Cas_Csd1 PF09709.5 EKE40268.1 - 0.065 11.5 0.0 0.083 11.1 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) DUF106 PF01956.11 EKE40269.1 - 6e-32 110.4 0.9 1e-31 109.7 0.7 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 Maelstrom PF13017.1 EKE40271.1 - 2.5e-41 141.5 1.4 3.1e-41 141.2 1.0 1.0 1 0 0 1 1 1 1 piRNA pathway germ-plasm component BRO1 PF03097.13 EKE40272.1 - 3.1e-06 26.1 0.6 3.1e-06 26.1 0.4 1.8 2 0 0 2 2 2 1 BRO1-like domain TPR_12 PF13424.1 EKE40272.1 - 3.8e-05 23.5 0.0 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKE40272.1 - 0.0022 17.5 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE40272.1 - 0.0057 16.3 1.2 0.037 13.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKE40272.1 - 0.082 12.7 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKE40272.1 - 0.11 12.5 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Actin PF00022.14 EKE40273.1 - 4.5e-45 153.7 0.0 8.7e-23 80.3 0.0 2.1 1 1 1 2 2 2 2 Actin Telomere_reg-2 PF10193.4 EKE40274.1 - 1.4e-07 31.7 0.5 8.7e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 Telomere length regulation protein GlutR_N PF05201.10 EKE40274.1 - 0.023 14.2 0.1 0.091 12.3 0.1 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain SecIII_SopE_N PF05364.9 EKE40274.1 - 0.63 9.9 4.9 2.4 8.0 0.2 3.1 2 1 1 3 3 3 0 Salmonella type III secretion SopE effector N-terminus LON PF02190.11 EKE40275.1 - 1.9e-05 24.4 1.2 2.7e-05 23.9 0.4 1.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain Yippee-Mis18 PF03226.9 EKE40275.1 - 0.19 11.7 6.8 1.4 8.9 4.3 2.5 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MSA-2c PF12238.3 EKE40275.1 - 2.4 7.7 4.7 1.2 8.7 1.2 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c DOCK-C2 PF14429.1 EKE40276.1 - 4e-31 108.0 1.7 4e-31 108.0 1.2 3.2 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins Vps26 PF03643.10 EKE40277.1 - 3.1e-30 104.8 8.7 4.8e-30 104.2 6.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EKE40277.1 - 1.2e-06 28.3 3.2 0.0005 19.8 0.4 3.1 2 2 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKE40277.1 - 0.032 14.3 2.1 0.14 12.2 1.4 2.1 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Pkinase_Tyr PF07714.12 EKE40278.1 - 3.3e-58 196.7 0.2 5.5e-58 196.0 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40278.1 - 7.4e-57 192.4 0.3 1.5e-56 191.4 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EKE40278.1 - 1.1e-24 86.5 2.2 4.5e-10 39.7 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE40278.1 - 1.9e-21 74.7 1.0 0.00023 20.8 0.1 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EKE40278.1 - 1.8e-20 72.8 3.8 5.8e-07 29.8 0.0 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE40278.1 - 7.4e-19 67.3 4.0 6e-08 32.6 0.2 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE40278.1 - 2.4e-18 64.4 5.9 0.00066 19.6 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat C2 PF00168.25 EKE40278.1 - 0.0022 17.8 0.2 0.0069 16.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain UQ_con PF00179.21 EKE40279.1 - 2.8e-42 143.4 0.0 3.2e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKE40279.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Lipocalin_4 PF13648.1 EKE40280.1 - 3 8.5 7.7 15 6.2 4.8 2.2 1 1 1 2 2 2 0 Lipocalin-like domain Nop PF01798.13 EKE40281.1 - 1.8e-40 137.6 0.9 2.2e-39 134.1 0.0 2.7 2 1 1 3 3 3 1 Putative snoRNA binding domain Prp31_C PF09785.4 EKE40281.1 - 3.4e-15 56.5 5.8 1e-14 55.0 4.0 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EKE40281.1 - 5.3e-12 45.3 0.6 5.3e-12 45.3 0.4 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain Metallophos PF00149.23 EKE40282.1 - 1.7e-29 102.6 0.0 2.1e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CitMHS PF03600.11 EKE40283.1 - 6.5e-09 34.8 43.0 0.0004 19.0 4.3 3.1 1 1 1 3 3 3 3 Citrate transporter TrkA_C PF02080.16 EKE40283.1 - 4.4e-05 22.9 0.1 7.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-C domain Tetraspannin PF00335.15 EKE40284.1 - 0.15 11.2 16.1 0.42 9.8 11.2 1.9 1 1 0 1 1 1 0 Tetraspanin family CD20 PF04103.10 EKE40284.1 - 0.83 9.5 18.3 1.8 8.4 12.2 1.8 1 1 1 2 2 2 0 CD20-like family DNA_primase_lrg PF04104.9 EKE40285.1 - 2.5e-41 141.6 1.9 4.8e-41 140.7 1.3 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit RAB3GAP2_N PF14655.1 EKE40288.1 - 0.059 12.3 1.9 0.072 12.0 1.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus KxDL PF10241.4 EKE40288.1 - 0.11 12.3 7.0 0.037 13.9 2.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein Tho2 PF11262.3 EKE40288.1 - 0.44 9.5 9.0 0.51 9.3 6.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MalF_P2 PF14785.1 EKE40288.1 - 0.48 10.2 3.0 0.5 10.2 2.1 1.2 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Uds1 PF15456.1 EKE40288.1 - 1.5 8.7 6.8 1.6 8.7 4.1 1.5 1 1 0 1 1 1 0 Up-regulated During Septation Mgr1 PF08602.5 EKE40288.1 - 2.5 7.0 6.2 2.8 6.8 4.3 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit ING PF12998.2 EKE40288.1 - 2.8 8.2 13.2 4.3 7.6 9.1 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding RNase_PH PF01138.16 EKE40289.1 - 5.3e-12 46.2 0.0 1.1e-11 45.1 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 CIMR PF00878.13 EKE40289.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Alkyl_sulf_dimr PF14863.1 EKE40290.1 - 1.4e-54 184.1 0.5 2.2e-54 183.5 0.4 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 EKE40290.1 - 8.5e-16 58.0 0.0 1.6e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 EKE40290.1 - 5.4e-10 39.2 0.0 1.9e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE40290.1 - 2.9e-06 26.9 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SCP2 PF02036.12 EKE40290.1 - 0.02 15.1 0.1 0.53 10.6 0.0 2.4 2 0 0 2 2 2 0 SCP-2 sterol transfer family AAA PF00004.24 EKE40291.1 - 5.6e-15 55.6 0.0 9.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EKE40291.1 - 4.3e-13 49.2 3.9 5.4e-12 45.6 0.5 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EKE40291.1 - 1.2e-08 34.1 0.4 4.9e-05 22.2 0.1 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EKE40291.1 - 4.5e-08 33.3 0.2 0.00065 19.8 0.0 2.8 1 1 2 3 3 3 2 AAA domain AAA_16 PF13191.1 EKE40291.1 - 1.2e-06 28.6 0.1 7.8e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EKE40291.1 - 2.1e-06 26.9 0.1 2.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EKE40291.1 - 2.1e-06 27.6 0.0 9.7e-06 25.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain Rep_fac_C PF08542.6 EKE40291.1 - 1e-05 25.4 1.0 0.0013 18.6 0.1 3.0 2 1 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.8 EKE40291.1 - 1.5e-05 24.5 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.8 EKE40291.1 - 0.0003 19.8 0.0 0.0014 17.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EKE40291.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EKE40291.1 - 0.0012 18.3 0.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.24 EKE40291.1 - 0.0063 16.0 0.1 0.4 10.1 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 EKE40291.1 - 0.0067 16.1 0.1 0.069 12.8 0.0 2.5 1 1 1 2 2 2 1 NTPase Mg_chelatase PF01078.16 EKE40291.1 - 0.0079 15.3 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EKE40291.1 - 0.0082 15.6 0.0 0.31 10.4 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain KTI12 PF08433.5 EKE40291.1 - 0.0088 15.2 0.1 0.017 14.3 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_3 PF07726.6 EKE40291.1 - 0.0088 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EKE40291.1 - 0.0096 15.3 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SNF2_N PF00176.18 EKE40291.1 - 0.014 14.1 0.1 2.7 6.7 0.0 3.0 2 1 0 3 3 3 0 SNF2 family N-terminal domain NACHT PF05729.7 EKE40291.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EKE40291.1 - 0.025 14.7 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EKE40291.1 - 0.03 13.5 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EKE40291.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EKE40291.1 - 0.038 12.7 0.0 0.24 10.1 0.0 2.2 2 1 0 2 2 2 0 ArgK protein Viral_helicase1 PF01443.13 EKE40291.1 - 0.044 13.2 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EKE40291.1 - 0.052 13.8 0.1 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EKE40291.1 - 0.054 13.1 0.1 0.13 11.9 0.1 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EKE40291.1 - 0.055 13.0 0.0 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 EKE40291.1 - 0.077 12.3 0.1 1.6 8.0 0.1 2.5 1 1 0 1 1 1 0 AAA domain SAP PF02037.22 EKE40292.1 - 0.00085 18.7 1.9 0.0014 18.1 1.3 1.3 1 0 0 1 1 1 1 SAP domain DUF1765 PF08578.5 EKE40294.1 - 4e-15 55.9 6.6 4e-15 55.9 4.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Vps35 PF03635.12 EKE40295.1 - 4.6e-107 359.0 46.9 1.7e-104 350.5 32.5 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Glyco_hydro_3_C PF01915.17 EKE40296.1 - 2.7 7.4 23.8 0.49 9.8 6.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain HhH-GPD PF00730.20 EKE40297.1 - 3.5e-14 52.9 0.0 6.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EKE40297.1 - 2.6e-09 36.2 0.0 7.3e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EKE40297.1 - 0.005 16.9 0.0 0.46 10.6 0.0 2.9 2 1 1 3 3 3 2 Helix-hairpin-helix domain HHH_2 PF12826.2 EKE40297.1 - 0.023 14.5 0.0 0.21 11.4 0.0 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix motif FlaC_arch PF05377.6 EKE40297.1 - 1.8 8.5 5.8 0.94 9.4 1.8 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FadA PF09403.5 EKE40297.1 - 2.2 8.3 7.2 4 7.4 5.0 1.4 1 0 0 1 1 1 0 Adhesion protein FadA RabGAP-TBC PF00566.13 EKE40298.1 - 1.7e-42 145.3 5.6 3.5e-42 144.3 3.9 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 EKE40298.1 - 3.5e-37 126.6 15.9 9.7e-14 51.4 0.4 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EKE40298.1 - 2.4e-23 80.7 4.4 1.7e-08 33.8 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EKE40298.1 - 7.6e-18 64.1 1.9 4.3e-06 26.7 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKE40298.1 - 2.8e-17 62.7 5.6 7.5e-07 29.4 0.1 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE40298.1 - 7e-15 53.6 3.9 0.0027 17.7 0.0 5.9 5 1 1 6 6 6 3 Ankyrin repeat TFIIB PF00382.14 EKE40298.1 - 0.06 13.1 1.6 2.1 8.2 0.1 3.0 1 1 1 2 2 2 0 Transcription factor TFIIB repeat Adeno_E3_15_3 PF03307.9 EKE40299.1 - 0.17 11.6 2.8 0.22 11.2 0.7 2.0 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region PP2C_2 PF13672.1 EKE40301.1 - 0.0029 17.0 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Cauli_DNA-bind PF03310.8 EKE40301.1 - 0.032 14.0 0.2 0.072 12.9 0.2 1.6 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DUF1542 PF07564.6 EKE40301.1 - 0.6 10.1 6.7 0.75 9.8 0.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) SPRY PF00622.23 EKE40302.1 - 3.4e-10 40.0 0.6 7.5e-10 38.9 0.4 1.6 1 0 0 1 1 1 1 SPRY domain MerR-DNA-bind PF09278.6 EKE40303.1 - 0.003 17.9 4.6 0.031 14.6 1.1 2.3 1 1 1 2 2 2 1 MerR, DNA binding FlgN PF05130.7 EKE40303.1 - 0.0066 16.6 0.4 0.0087 16.3 0.3 1.1 1 0 0 1 1 1 1 FlgN protein Baculo_PEP_C PF04513.7 EKE40303.1 - 0.0074 16.1 0.2 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_5 PF01795.14 EKE40303.1 - 0.017 14.4 0.3 0.018 14.2 0.2 1.1 1 0 0 1 1 1 0 MraW methylase family Osmo_CC PF08946.5 EKE40303.1 - 0.027 14.5 1.5 0.027 14.5 1.0 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil PNPase PF03726.9 EKE40303.1 - 0.03 14.6 1.2 0.049 13.8 0.9 1.4 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4164 PF13747.1 EKE40303.1 - 0.095 12.8 1.7 3.6 7.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Apolipoprotein PF01442.13 EKE40303.1 - 0.099 12.1 0.3 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Syntaxin PF00804.20 EKE40303.1 - 0.11 12.6 0.9 0.15 12.2 0.6 1.2 1 0 0 1 1 1 0 Syntaxin DUF677 PF05055.7 EKE40303.1 - 0.11 11.1 2.8 0.14 10.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) MmgE_PrpD PF03972.9 EKE40303.1 - 0.13 10.4 0.1 0.15 10.1 0.0 1.0 1 0 0 1 1 1 0 MmgE/PrpD family DUF1664 PF07889.7 EKE40303.1 - 0.29 10.9 3.7 1 9.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L37ae PF01780.14 EKE40304.1 - 7.7e-38 128.2 8.9 8.8e-38 128.0 6.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EKE40304.1 - 0.011 15.5 7.8 0.015 15.0 5.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EKE40304.1 - 0.018 14.4 5.2 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EKE40304.1 - 1.5 8.8 5.4 5.3 7.0 0.7 2.5 2 1 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 EKE40304.1 - 4.8 7.0 7.8 0.66 9.7 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger Pkinase PF00069.20 EKE40305.1 - 2.8e-65 220.0 0.0 3.4e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40305.1 - 6.2e-31 107.4 0.0 1.1e-29 103.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE40305.1 - 0.00096 18.1 0.0 0.003 16.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EKE40305.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EKE40305.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EKE40305.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKE40305.1 - 0.082 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MIG-14_Wnt-bd PF06664.7 EKE40306.1 - 0.0017 17.2 26.7 0.0017 17.2 18.5 2.0 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion Pkinase PF00069.20 EKE40307.1 - 1.9e-60 204.1 0.7 5.8e-60 202.6 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40307.1 - 1.8e-37 128.8 0.2 4e-37 127.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE40307.1 - 1.4e-07 30.8 0.0 4e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKE40307.1 - 0.00082 19.1 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ras PF00071.17 EKE40308.1 - 2.9e-52 176.3 0.0 3.5e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40308.1 - 1.1e-19 71.1 0.0 2.7e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE40308.1 - 1.7e-13 50.1 0.0 2.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE40308.1 - 0.00086 18.5 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE40308.1 - 0.0014 18.1 1.0 0.05 13.0 0.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EKE40308.1 - 0.0039 15.9 0.7 1.2 7.7 0.0 2.6 2 1 1 3 3 3 2 G-protein alpha subunit AAA_22 PF13401.1 EKE40308.1 - 0.0086 16.2 0.0 0.052 13.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EKE40308.1 - 0.01 15.9 0.4 0.068 13.3 0.3 2.1 1 1 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 EKE40308.1 - 0.013 15.0 0.1 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 EKE40308.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.9 EKE40308.1 - 0.055 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EKE40308.1 - 0.062 12.8 1.2 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EKE40308.1 - 0.075 12.0 0.2 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_33 PF13671.1 EKE40308.1 - 0.094 12.5 0.2 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EKE40308.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC cobW PF02492.14 EKE40308.1 - 0.17 11.3 0.4 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RelB_N PF12910.2 EKE40309.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal WD40 PF00400.27 EKE40310.1 - 3.1e-07 30.0 0.0 0.69 9.8 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Cullin PF00888.17 EKE40311.1 - 2.6e-55 188.0 19.7 4.4e-55 187.3 13.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EKE40311.1 - 4.5e-20 71.2 5.0 4.5e-20 71.2 3.5 2.8 3 0 0 3 3 3 1 Cullin protein neddylation domain Toxin_R_bind_C PF07951.7 EKE40311.1 - 0.096 12.3 8.3 0.6 9.7 3.1 2.9 2 0 0 2 2 2 0 Clostridium neurotoxin, C-terminal receptor binding DUF4304 PF14137.1 EKE40312.1 - 0.054 13.6 3.5 0.18 11.9 2.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) DUF4604 PF15377.1 EKE40312.1 - 1 9.5 16.0 0.36 11.0 9.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) LMBR1 PF04791.11 EKE40312.1 - 7 5.1 5.9 8.2 4.8 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 EKE40312.1 - 9.5 6.0 9.1 1.5 8.6 2.9 1.9 1 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Myb_DNA-binding PF00249.26 EKE40313.1 - 1.1e-09 38.1 0.2 1.3e-08 34.7 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE40313.1 - 0.00012 22.0 0.3 0.00012 22.0 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Med19 PF10278.4 EKE40313.1 - 0.0039 16.8 3.6 0.0039 16.8 2.5 1.9 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 Myb_DNA-bind_5 PF13873.1 EKE40313.1 - 0.0094 15.8 3.2 0.4 10.6 0.3 3.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.5 EKE40313.1 - 0.1 12.3 6.7 0.32 10.7 3.7 2.5 1 1 1 2 2 2 0 SLIDE DUF2992 PF11208.3 EKE40313.1 - 2.4 8.0 14.8 0.59 10.0 7.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Alpha_kinase PF02816.13 EKE40314.1 - 4.1e-24 85.2 3.3 4.1e-24 85.2 2.3 3.3 2 1 0 3 3 3 1 Alpha-kinase family Citrate_ly_lig PF08218.6 EKE40314.1 - 0.0051 16.2 2.6 0.34 10.3 0.0 3.1 2 1 0 3 3 3 2 Citrate lyase ligase C-terminal domain LRR_4 PF12799.2 EKE40316.1 - 3.3e-42 141.4 105.2 9.2e-08 31.5 1.4 13.2 7 4 5 12 12 12 12 Leucine Rich repeats (2 copies) PP2C PF00481.16 EKE40316.1 - 7.4e-38 130.3 0.0 1.3e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EKE40316.1 - 6.6e-35 118.6 89.0 5.1e-09 35.7 3.2 10.6 3 3 10 14 14 14 14 Leucine rich repeat LRR_1 PF00560.28 EKE40316.1 - 7.1e-19 64.9 112.0 0.041 13.9 0.4 21.7 20 3 2 22 22 22 12 Leucine Rich Repeat LRR_7 PF13504.1 EKE40316.1 - 6.7e-17 58.6 65.8 0.25 11.6 0.0 19.1 21 1 0 21 21 21 7 Leucine rich repeat LRR_6 PF13516.1 EKE40316.1 - 5.2e-07 29.0 88.5 1.5 9.0 0.5 19.1 16 3 2 18 18 18 6 Leucine Rich repeat PP2C_2 PF13672.1 EKE40316.1 - 0.0012 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3884 PF13024.1 EKE40316.1 - 0.0071 15.7 0.5 0.036 13.4 0.3 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3884) LysM PF01476.15 EKE40316.1 - 0.046 13.6 1.2 0.37 10.7 0.1 2.9 2 0 0 2 2 2 0 LysM domain CDP-OH_P_transf PF01066.16 EKE40317.1 - 3e-13 49.9 20.2 4.2e-12 46.2 14.0 2.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MIF4G_like PF09088.6 EKE40317.1 - 0.062 12.7 0.2 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 MIF4G like Orbi_NS3 PF01616.11 EKE40317.1 - 0.21 10.5 0.2 0.35 9.7 0.2 1.3 1 0 0 1 1 1 0 Orbivirus NS3 Ras PF00071.17 EKE40318.1 - 0.0037 16.6 0.1 0.0076 15.6 0.1 1.5 1 0 0 1 1 1 1 Ras family Nnf1 PF03980.9 EKE40318.1 - 0.0055 16.6 3.4 0.03 14.3 0.1 2.4 1 1 1 2 2 2 2 Nnf1 UPF0160 PF03690.8 EKE40320.1 - 7e-38 130.8 0.0 1.1e-37 130.1 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) LRR_9 PF14580.1 EKE40321.1 - 0.00016 21.3 0.6 0.00052 19.6 0.4 1.9 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.15 EKE40321.1 - 0.0012 19.2 0.0 0.012 15.9 0.0 2.4 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 EKE40321.1 - 0.0035 16.9 9.6 0.014 15.0 2.6 3.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) UBN2 PF14223.1 EKE40321.1 - 0.16 11.8 1.1 8.8 6.1 0.0 3.4 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type LRR_8 PF13855.1 EKE40321.1 - 0.4 10.4 10.2 0.83 9.4 4.3 3.3 3 1 0 3 3 3 0 Leucine rich repeat Pkinase PF00069.20 EKE40322.1 - 2.2e-39 135.1 0.0 3.3e-39 134.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40322.1 - 3.4e-14 52.5 0.0 4.8e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE40322.1 - 0.013 15.2 0.0 4 7.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Decorin_bind PF02352.10 EKE40323.1 - 0.062 13.3 0.1 0.096 12.6 0.1 1.2 1 0 0 1 1 1 0 Decorin binding protein Sec23_BS PF08033.7 EKE40324.1 - 2.2e-08 34.5 0.1 1.9e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Clathrin_bdg PF15045.1 EKE40324.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking zf-Sec23_Sec24 PF04810.10 EKE40324.1 - 0.0083 15.6 8.0 0.018 14.5 5.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Adaptin_N PF01602.15 EKE40325.1 - 8.5e-93 311.4 14.0 1.1e-92 311.1 9.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EKE40325.1 - 6.8e-23 80.7 0.0 2.3e-22 79.0 0.0 2.0 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Humanin PF15040.1 EKE40325.1 - 0.05 12.8 0.4 0.11 11.7 0.3 1.6 1 0 0 1 1 1 0 Humanin family HEAT_2 PF13646.1 EKE40325.1 - 0.066 13.5 0.0 16 5.8 0.0 3.6 2 2 1 3 3 3 0 HEAT repeats Pkinase PF00069.20 EKE40328.1 - 0.0014 17.7 0.1 0.0051 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain HAD PF12710.2 EKE40329.1 - 6.6e-18 65.5 0.1 4.5e-17 62.8 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE40329.1 - 6e-16 59.4 0.0 2.9e-15 57.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EKE40329.1 - 9.5e-14 50.9 0.9 2.1e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EKE40329.1 - 1.3e-09 37.9 0.0 4.8e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKE40329.1 - 2.1e-07 30.8 1.5 0.00028 20.5 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase NPBW PF15180.1 EKE40329.1 - 0.017 14.7 0.0 0.055 13.1 0.0 1.8 2 0 0 2 2 2 0 Neuropeptides B and W THP2 PF09432.5 EKE40329.1 - 0.021 14.7 1.7 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 Tho complex subunit THP2 Attractin PF08037.6 EKE40329.1 - 2.1 8.2 6.5 1.5 8.6 0.6 2.4 1 1 0 2 2 2 0 Attractin family Sigma_reg_N PF13800.1 EKE40329.1 - 2.6 8.1 6.6 11 6.1 0.0 3.9 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Reo_sigmaC PF04582.7 EKE40330.1 - 0.29 10.2 5.9 0.41 9.7 0.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Inhibitor_I42 PF09394.5 EKE40331.1 - 0.00069 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Rhodanese PF00581.15 EKE40332.1 - 1e-07 32.2 0.3 3.3e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain RabGAP-TBC PF00566.13 EKE40332.1 - 2.2e-06 27.3 7.3 2.2e-06 27.3 5.1 2.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain bPH_3 PF14470.1 EKE40332.1 - 0.0014 18.8 3.2 0.0066 16.6 2.2 2.2 1 0 0 1 1 1 1 Bacterial PH domain CDC27 PF09507.5 EKE40332.1 - 1.3 8.2 36.8 13 4.8 24.6 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DDHD PF02862.12 EKE40332.1 - 6.4 6.4 14.4 14 5.4 10.0 1.6 1 0 0 1 1 1 0 DDHD domain zf-C2H2_2 PF12756.2 EKE40333.1 - 1.1e-26 92.8 32.1 4.8e-24 84.4 7.5 3.0 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EKE40333.1 - 5.9e-09 35.8 14.8 3.5e-07 30.2 3.0 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EKE40333.1 - 2.6e-08 33.7 6.8 2.6e-08 33.7 4.7 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EKE40333.1 - 0.016 15.4 23.6 0.027 14.8 0.8 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger IMD PF08397.6 EKE40333.1 - 0.094 12.0 7.8 0.18 11.0 5.4 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain SIM_C PF06621.7 EKE40335.1 - 0.00017 21.3 0.5 0.00017 21.2 0.3 1.1 1 0 0 1 1 1 1 Single-minded protein C-terminus DUF948 PF06103.6 EKE40335.1 - 0.024 14.4 3.8 0.047 13.5 2.6 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Apo-VLDL-II PF05418.6 EKE40335.1 - 0.035 14.2 0.3 0.054 13.6 0.2 1.2 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) CHASE3 PF05227.8 EKE40335.1 - 0.04 13.5 2.6 0.058 13.0 1.8 1.3 1 0 0 1 1 1 0 CHASE3 domain GTPase_Cys_C PF12631.2 EKE40335.1 - 0.078 13.3 0.4 0.078 13.3 0.3 1.5 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE CENP-T PF15511.1 EKE40335.1 - 0.56 9.4 4.8 0.63 9.2 3.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF848 PF05852.6 EKE40335.1 - 0.56 10.0 7.0 0.52 10.1 4.2 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Kri1 PF05178.7 EKE40335.1 - 0.58 10.4 11.1 1.9 8.7 7.7 2.1 1 1 0 1 1 1 0 KRI1-like family V_ATPase_I PF01496.14 EKE40335.1 - 9.6 3.9 7.4 9.5 3.9 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family mRNA_cap_enzyme PF01331.14 EKE40336.1 - 9.5e-19 67.8 7.4 1.8e-18 66.9 4.0 2.2 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EKE40336.1 - 0.0042 17.3 0.3 0.0042 17.3 0.2 2.8 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Shugoshin_N PF07558.6 EKE40339.1 - 0.0049 16.5 1.8 0.0049 16.5 1.2 3.2 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region Strep_SA_rep PF06696.6 EKE40339.1 - 4.7 7.0 7.2 4.8 7.0 0.3 2.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF4612 PF15389.1 EKE40340.1 - 1.9 9.1 6.4 8.7 6.9 4.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4612) HEAT_2 PF13646.1 EKE40341.1 - 0.00097 19.3 0.0 1.4 9.2 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats DUF2680 PF10925.3 EKE40342.1 - 0.052 13.4 6.3 0.18 11.7 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) H_lectin PF09458.5 EKE40343.1 - 4.2e-07 29.5 12.5 1.2e-06 28.0 1.8 3.4 3 1 0 3 3 3 2 H-type lectin domain zf-C3HC4_3 PF13920.1 EKE40343.1 - 0.0022 17.6 17.6 0.0063 16.1 12.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CK_II_beta PF01214.13 EKE40344.1 - 2.5e-60 203.1 0.0 3e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zf-ribbon_3 PF13248.1 EKE40344.1 - 0.33 10.2 3.1 1 8.6 0.4 2.4 1 1 1 2 2 1 0 zinc-ribbon domain TLD PF07534.11 EKE40345.1 - 5.1e-06 26.5 0.4 1.1e-05 25.3 0.2 1.6 1 1 0 1 1 1 1 TLD LANC_like PF05147.8 EKE40345.1 - 0.03 12.8 0.4 0.03 12.8 0.2 1.7 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein Adaptin_N PF01602.15 EKE40346.1 - 1.7e-136 455.6 15.4 1.7e-136 455.6 10.7 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 EKE40346.1 - 3.3e-26 92.2 0.1 3.3e-26 92.2 0.0 3.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EKE40346.1 - 4.7e-16 58.8 0.4 4.4e-08 33.2 0.0 5.7 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 EKE40346.1 - 1.5e-09 37.1 1.4 0.03 14.3 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 EKE40346.1 - 1.5e-05 24.6 1.8 2.2 8.2 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EKE40346.1 - 2.1e-05 24.8 0.5 0.29 11.6 0.0 5.6 7 1 0 7 7 7 1 HEAT-like repeat Cnd3 PF12719.2 EKE40346.1 - 0.00079 18.4 4.3 0.014 14.4 0.8 3.1 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Alpha_adaptinC2 PF02883.15 EKE40346.1 - 0.0015 18.7 0.1 0.0043 17.3 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain B2-adapt-app_C PF09066.5 EKE40346.1 - 0.0016 18.2 0.7 0.0048 16.7 0.5 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain CLASP_N PF12348.3 EKE40346.1 - 0.014 14.7 0.3 1.9 7.7 0.0 3.2 3 1 0 3 3 3 0 CLASP N terminal PBP1_TM PF14812.1 EKE40347.1 - 5.3 7.4 18.9 0.35 11.1 2.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ras PF00071.17 EKE40348.1 - 1.1e-41 141.9 1.0 1.5e-41 141.5 0.7 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40348.1 - 8.6e-16 58.5 0.4 1.8e-15 57.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE40348.1 - 1.2e-10 40.9 0.3 1.6e-10 40.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE40348.1 - 0.00097 19.0 0.4 0.0035 17.3 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKE40348.1 - 0.0029 16.8 0.2 0.0096 15.1 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 EKE40348.1 - 0.0044 16.0 0.0 0.0082 15.1 0.0 1.4 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EKE40348.1 - 0.0072 15.7 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE40348.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EKE40348.1 - 0.033 13.4 0.6 6.9 5.9 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF3235 PF11574.3 EKE40348.1 - 0.045 13.9 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) HTH_Tnp_1 PF01527.15 EKE40349.1 - 0.013 15.3 0.1 0.044 13.7 0.0 1.9 1 1 0 1 1 1 0 Transposase SYF2 PF08231.7 EKE40349.1 - 0.2 11.8 5.4 0.049 13.7 1.1 1.8 1 1 1 2 2 2 0 SYF2 splicing factor RsbRD_N PF14361.1 EKE40350.1 - 1.3 9.5 4.0 1.4 9.3 0.1 2.9 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Y_phosphatase PF00102.22 EKE40351.1 - 1.1e-54 185.3 0.4 1.8e-53 181.2 0.3 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EKE40351.1 - 6.8e-05 22.4 1.4 0.00094 18.7 0.0 2.6 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CesA PF11439.3 EKE40351.1 - 0.0075 16.1 0.7 0.016 15.1 0.5 1.5 1 0 0 1 1 1 1 Type III secretion system filament chaperone CesA PTPlike_phytase PF14566.1 EKE40351.1 - 0.4 10.7 2.4 1.1 9.2 0.0 2.7 3 1 1 4 4 4 0 Inositol hexakisphosphate Coatomer_WDAD PF04053.9 EKE40352.1 - 6.6e-101 338.2 0.1 2.9e-100 336.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EKE40352.1 - 1.6e-57 189.4 14.3 2.2e-10 39.9 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF1513 PF07433.6 EKE40352.1 - 0.0062 15.4 0.0 0.048 12.5 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1513) Nup160 PF11715.3 EKE40352.1 - 0.019 13.1 9.1 0.38 8.8 0.0 4.6 3 2 2 5 5 5 0 Nucleoporin Nup120/160 B3_4 PF03483.12 EKE40353.1 - 0.0012 18.3 0.1 0.0014 18.1 0.1 1.0 1 0 0 1 1 1 1 B3/4 domain Sigma70_r1_1 PF03979.9 EKE40353.1 - 0.056 13.3 1.5 0.071 13.0 0.7 1.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Phe_tRNA-synt_N PF02912.13 EKE40353.1 - 0.091 12.5 0.2 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain TLD PF07534.11 EKE40354.1 - 0.0019 18.2 0.5 0.0019 18.2 0.3 2.2 2 1 1 3 3 3 1 TLD Flavokinase PF01687.12 EKE40354.1 - 0.11 12.4 1.6 0.17 11.7 1.1 1.3 1 0 0 1 1 1 0 Riboflavin kinase NAM-associated PF14303.1 EKE40354.1 - 0.15 12.3 8.2 0.23 11.7 5.7 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DEAD PF00270.24 EKE40355.1 - 1.2e-35 122.4 0.1 2.2e-33 115.1 0.1 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE40355.1 - 2.3e-24 85.0 0.1 7.8e-24 83.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE40355.1 - 1.6e-09 37.9 0.0 4.8e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EKE40355.1 - 0.0024 16.9 0.8 0.004 16.2 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit PS_pyruv_trans PF04230.8 EKE40355.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase AAA PF00004.24 EKE40356.1 - 4.2e-38 130.5 0.0 1.4e-37 128.8 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EKE40356.1 - 1.9e-08 34.0 0.0 6e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 EKE40356.1 - 1.2e-05 25.1 0.1 7.4e-05 22.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EKE40356.1 - 1.3e-05 24.3 0.0 3.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKE40356.1 - 1.5e-05 25.1 0.3 0.0012 18.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKE40356.1 - 0.00013 21.8 0.0 0.00054 19.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EKE40356.1 - 0.00041 20.2 0.6 0.037 13.9 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EKE40356.1 - 0.0007 20.4 0.3 0.006 17.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EKE40356.1 - 0.0017 17.1 0.0 0.0032 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 EKE40356.1 - 0.01 15.3 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EKE40356.1 - 0.01 15.2 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EKE40356.1 - 0.012 14.8 0.3 0.031 13.4 0.2 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EKE40356.1 - 0.014 14.9 0.4 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EKE40356.1 - 0.018 14.7 1.5 0.13 12.0 0.1 2.4 2 1 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EKE40356.1 - 0.031 14.2 0.3 0.3 11.0 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EKE40356.1 - 0.038 14.2 1.8 0.19 12.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EKE40356.1 - 0.067 12.5 1.1 0.62 9.4 0.2 2.4 1 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 EKE40356.1 - 0.13 12.1 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EKE40356.1 - 0.13 11.8 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EKE40356.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.22 EKE40357.1 - 5.6e-33 113.6 0.0 8.2e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Vps51 PF08700.6 EKE40359.1 - 4.4e-07 29.6 4.1 4.4e-07 29.6 2.8 3.4 3 1 1 4 4 4 1 Vps51/Vps67 Dor1 PF04124.7 EKE40359.1 - 7.8e-07 27.8 11.4 1.6e-06 26.8 7.9 1.5 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 EKE40359.1 - 2.8e-05 23.9 13.9 2.8e-05 23.9 9.6 2.4 3 1 0 3 3 3 1 Exocyst complex component Sec5 COG2 PF06148.6 EKE40359.1 - 0.0011 18.8 2.5 0.0011 18.8 1.7 3.3 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 EKE40359.1 - 0.076 12.9 7.0 3 7.8 0.0 4.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) KMP11 PF03037.11 EKE40359.1 - 0.1 13.1 5.2 13 6.4 0.1 3.5 2 1 1 3 3 3 0 Kinetoplastid membrane protein 11 Baculo_PEP_C PF04513.7 EKE40359.1 - 0.41 10.4 14.7 0.017 14.9 2.7 3.3 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EKE40359.1 - 0.74 9.6 11.7 1.2 8.9 0.3 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) AAA_18 PF13238.1 EKE40359.1 - 0.92 9.8 8.6 0.18 12.1 2.4 2.4 1 1 1 2 2 2 0 AAA domain WEMBL PF05701.6 EKE40359.1 - 1 7.7 9.6 0.19 10.1 2.0 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Syntaxin-6_N PF09177.6 EKE40359.1 - 1.9 8.9 7.5 4.7 7.6 0.8 3.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal COG5 PF10392.4 EKE40359.1 - 3.3 7.6 17.4 0.35 10.8 1.0 3.5 2 1 1 3 3 3 0 Golgi transport complex subunit 5 IFT20 PF14931.1 EKE40359.1 - 3.8 7.4 14.5 0.36 10.7 3.3 3.3 1 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Fib_alpha PF08702.5 EKE40359.1 - 10 6.2 20.2 1.8 8.6 0.6 3.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Methyltransf_PK PF05891.7 EKE40360.1 - 3.8e-46 157.1 1.2 4.4e-46 156.9 0.8 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_12 PF08242.7 EKE40360.1 - 2.7e-08 34.1 0.1 5.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE40360.1 - 9.8e-07 28.6 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE40360.1 - 2.2e-06 28.0 0.0 3.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EKE40360.1 - 1e-05 24.8 0.2 1.6e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 EKE40360.1 - 1.1e-05 24.8 0.3 2.2e-05 23.8 0.2 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EKE40360.1 - 0.00023 21.4 0.1 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EKE40360.1 - 0.00043 19.7 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_31 PF13847.1 EKE40360.1 - 0.00072 19.1 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE40360.1 - 0.0014 19.2 0.4 0.0057 17.2 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EKE40360.1 - 0.0091 15.3 0.1 0.49 9.6 0.1 2.1 1 1 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EKE40360.1 - 0.01 15.2 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Bin3 PF06859.7 EKE40360.1 - 0.058 13.4 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_24 PF13578.1 EKE40360.1 - 0.13 13.0 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TUDOR PF00567.19 EKE40361.1 - 0.0065 16.3 0.1 0.028 14.2 0.0 2.1 1 1 1 2 2 2 1 Tudor domain DUF4549 PF15082.1 EKE40361.1 - 0.55 9.8 6.9 1.1 8.8 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) DUF1759 PF03564.10 EKE40362.1 - 0.015 15.1 1.7 0.022 14.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF1765 PF08578.5 EKE40362.1 - 2.4 8.2 6.1 0.93 9.5 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) Alkyl_sulf_dimr PF14863.1 EKE40363.1 - 1.4e-51 174.4 0.0 2.3e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 EKE40363.1 - 8e-13 48.4 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 EKE40363.1 - 6.8e-11 42.1 0.0 2.1e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE40363.1 - 3.3e-08 33.3 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_11 PF13414.1 EKE40363.1 - 0.0017 17.9 0.3 0.0034 17.0 0.2 1.4 1 0 0 1 1 1 1 TPR repeat Apc3 PF12895.2 EKE40363.1 - 0.025 14.7 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EKE40363.1 - 0.058 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Form_Nir_trans PF01226.12 EKE40364.1 - 5.5e-64 215.4 20.5 6.3e-64 215.2 14.2 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Helicase_C PF00271.26 EKE40365.1 - 5.6e-23 80.5 0.1 4.4e-19 68.1 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EKE40365.1 - 3.1e-19 69.0 0.3 4.8e-18 65.2 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EKE40365.1 - 0.0001 22.2 3.8 0.0027 17.5 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Response_reg PF00072.19 EKE40365.1 - 0.091 12.7 0.1 22 5.1 0.0 3.4 4 0 0 4 4 4 0 Response regulator receiver domain MMR_HSR1 PF01926.18 EKE40366.1 - 2.4e-14 53.2 0.0 5.2e-12 45.7 0.0 3.0 2 1 1 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE40366.1 - 1.3e-05 24.5 0.2 0.00043 19.6 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 EKE40366.1 - 0.0022 17.1 0.0 0.005 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 EKE40366.1 - 0.63 8.7 3.2 0.45 9.2 0.0 2.3 2 2 0 2 2 2 0 ArgK protein HHH PF00633.18 EKE40367.1 - 1.6e-07 30.6 0.0 4.7e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 EKE40367.1 - 0.00033 20.9 0.0 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Cdd1 PF11731.3 EKE40367.1 - 0.00097 19.0 0.0 0.0053 16.6 0.0 2.1 1 1 0 1 1 1 1 Pathogenicity locus IMS_HHH PF11798.3 EKE40367.1 - 0.0059 16.5 0.4 0.065 13.3 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif DUF3962 PF13111.1 EKE40367.1 - 0.0094 15.3 0.4 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3962) HHH_5 PF14520.1 EKE40367.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4507 PF14964.1 EKE40367.1 - 0.025 13.3 0.1 0.043 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) HHH_8 PF14716.1 EKE40367.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_3 PF12836.2 EKE40367.1 - 0.079 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif WD40 PF00400.27 EKE40369.1 - 4.7e-08 32.6 6.4 0.00099 18.9 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE40369.1 - 0.13 12.0 0.1 2.7 7.7 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ADAM_CR PF08516.7 EKE40370.1 - 0.015 15.3 0.2 0.015 15.3 0.1 3.0 3 0 0 3 3 3 0 ADAM cysteine-rich BRE1 PF08647.6 EKE40372.1 - 0.0055 16.6 14.3 0.0055 16.6 9.9 2.9 2 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase DUF3166 PF11365.3 EKE40372.1 - 1.6 9.2 6.8 1.7 9.1 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Crystall PF00030.14 EKE40373.1 - 0.035 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Wzy_C PF04932.10 EKE40375.1 - 0.00037 20.3 3.1 0.00045 20.0 2.1 1.1 1 0 0 1 1 1 1 O-Antigen ligase WD40 PF00400.27 EKE40376.1 - 1.5e-23 81.7 1.7 4.5e-07 29.4 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EKE40376.1 - 0.0003 20.9 0.0 0.072 13.3 0.0 3.1 3 0 0 3 3 3 1 PQQ-like domain PQQ_2 PF13360.1 EKE40376.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.11 EKE40376.1 - 0.051 11.8 0.0 1.1 7.5 0.0 2.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain PQQ PF01011.16 EKE40376.1 - 0.11 12.0 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat WD40 PF00400.27 EKE40378.1 - 6.3e-06 25.8 0.1 6.3e-06 25.8 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE40378.1 - 0.022 14.5 0.3 7.9 6.2 0.0 3.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region F-box-like PF12937.2 EKE40378.1 - 0.022 14.4 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 F-box-like WD40 PF00400.27 EKE40379.1 - 0.36 10.7 6.1 0.092 12.6 0.3 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Skp1 PF01466.14 EKE40380.1 - 3.6e-38 129.4 0.4 6.4e-38 128.6 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EKE40380.1 - 5.2e-19 68.1 0.1 1.3e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EKE40380.1 - 0.028 14.3 0.2 0.24 11.4 0.2 2.0 1 1 0 1 1 1 0 BTB/POZ domain DUF3749 PF12568.3 EKE40380.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain VPS9 PF02204.13 EKE40381.1 - 4.9e-05 23.2 0.1 0.00014 21.8 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain FKS1_dom1 PF14288.1 EKE40382.1 - 0.09 12.6 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 CBFD_NFYB_HMF PF00808.18 EKE40383.1 - 1.4e-13 50.6 0.1 2.3e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKE40383.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3698 PF12479.3 EKE40383.1 - 0.015 15.3 0.7 0.026 14.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) RNase_H2-Ydr279 PF09468.5 EKE40383.1 - 0.097 11.8 2.6 0.13 11.3 1.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1767 PF08585.7 EKE40384.1 - 8.5e-09 35.5 1.0 8.5e-09 35.5 0.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) EF-hand_2 PF09068.6 EKE40384.1 - 0.021 14.9 0.1 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 EF hand HEAT PF02985.17 EKE40385.1 - 3.2e-06 26.7 0.1 9 6.6 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EKE40385.1 - 1.2e-05 25.6 4.1 1.1 9.6 0.0 4.9 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region FRQ PF09421.5 EKE40387.1 - 0.094 10.4 0.0 0.12 10.1 0.0 1.0 1 0 0 1 1 1 0 Frequency clock protein Pro_isomerase PF00160.16 EKE40389.1 - 2.4e-41 141.5 0.7 2.8e-41 141.3 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cas_VVA1548 PF09652.5 EKE40389.1 - 0.019 14.9 0.0 0.055 13.4 0.0 1.7 1 1 1 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) SAS4 PF15460.1 EKE40389.1 - 0.14 12.0 0.1 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 GPI-anchored PF10342.4 EKE40390.1 - 0.033 14.6 0.7 0.084 13.3 0.5 1.7 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mga PF05043.8 EKE40390.1 - 0.068 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain fn3 PF00041.16 EKE40390.1 - 0.16 12.1 1.2 0.41 10.8 0.3 1.9 2 0 0 2 2 2 0 Fibronectin type III domain KH_3 PF13014.1 EKE40391.1 - 0.00033 20.2 0.1 0.0013 18.3 0.1 2.1 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 EKE40391.1 - 0.00053 19.5 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 KH domain Lyase_8_C PF02884.12 EKE40391.1 - 0.0092 15.9 0.0 0.33 10.9 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain ArfGap PF01412.13 EKE40392.1 - 2.1e-30 104.8 0.0 2.1e-30 104.8 0.0 3.0 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EKE40392.1 - 2e-11 44.0 2.4 6e-06 26.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE40392.1 - 1.2e-07 31.6 0.2 3.5e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PH PF00169.24 EKE40392.1 - 4.5e-07 30.0 2.7 5.5e-07 29.7 0.3 2.4 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.1 EKE40392.1 - 1e-05 25.8 0.2 3.3e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EKE40392.1 - 0.00014 21.5 0.0 0.00045 19.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat PH_11 PF15413.1 EKE40392.1 - 0.012 15.8 0.9 0.1 12.8 0.6 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain Ank_3 PF13606.1 EKE40392.1 - 0.023 14.8 0.2 0.1 12.9 0.2 2.1 1 0 0 1 1 1 0 Ankyrin repeat Peptidase_C12 PF01088.16 EKE40393.1 - 3.4e-25 88.5 0.4 3.9e-25 88.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 FragX_IP PF05994.6 EKE40393.1 - 0.0053 14.5 0.1 0.0076 14.0 0.1 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family UCH PF00443.24 EKE40394.1 - 5.3e-23 81.4 4.7 1.1e-22 80.4 3.3 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EKE40394.1 - 2.3e-08 34.0 1.4 5.1e-08 32.9 1.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF3393 PF11873.3 EKE40394.1 - 0.031 13.7 1.8 2.1 7.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3393) Tmemb_14 PF03647.8 EKE40395.1 - 5.4e-05 23.5 0.2 5.4e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Transmembrane proteins 14C Peptidase_M56 PF05569.6 EKE40395.1 - 0.0051 15.8 0.4 0.0051 15.8 0.3 1.9 1 1 0 2 2 2 1 BlaR1 peptidase M56 DUF912 PF06024.7 EKE40395.1 - 0.0053 16.7 0.3 0.0053 16.7 0.2 2.4 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) NfeD PF01957.13 EKE40395.1 - 0.013 15.6 0.8 0.4 10.8 0.0 2.6 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4013 PF13197.1 EKE40395.1 - 0.015 14.5 12.4 0.35 10.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) DUF788 PF05620.6 EKE40395.1 - 0.016 15.0 10.1 0.029 14.2 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF788) Tetraspannin PF00335.15 EKE40395.1 - 0.04 13.1 0.2 0.04 13.1 0.2 3.0 2 1 1 3 3 2 0 Tetraspanin family DUF1183 PF06682.7 EKE40395.1 - 0.061 12.9 0.1 1.2 8.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1183) PBP1_TM PF14812.1 EKE40395.1 - 0.16 12.3 2.2 14 6.0 0.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 7tm_1 PF00001.16 EKE40395.1 - 0.24 10.5 5.3 0.32 10.1 1.7 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) RAMP4 PF06624.7 EKE40395.1 - 1.2 8.7 3.2 9.4 5.8 0.0 2.7 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 DUF3054 PF11255.3 EKE40395.1 - 2.3 8.1 7.1 0.69 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) ABC2_membrane_2 PF12679.2 EKE40395.1 - 2.6 6.8 7.3 41 2.8 5.0 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein PgaD PF13994.1 EKE40395.1 - 3.4 7.1 7.4 3.8 6.9 0.0 2.9 2 1 1 3 3 3 0 PgaD-like protein TLD PF07534.11 EKE40396.1 - 1.6e-07 31.3 1.3 2.1e-07 31.0 0.9 1.2 1 0 0 1 1 1 1 TLD DNA_primase_lrg PF04104.9 EKE40397.1 - 4e-26 91.8 3.4 5.5e-26 91.3 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit tRNA_anti-codon PF01336.20 EKE40398.1 - 2.7e-05 23.9 0.3 0.00017 21.3 0.1 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF104 PF01954.11 EKE40399.1 - 0.65 10.0 5.6 0.22 11.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF104 POP1 PF06978.6 EKE40400.1 - 1.1e-21 77.4 22.5 1.1e-11 44.7 5.6 3.1 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EKE40400.1 - 1.1e-11 44.4 0.3 1.1e-11 44.4 0.2 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain Inhibitor_I9 PF05922.11 EKE40400.1 - 2.4 8.8 5.3 5.1 7.7 0.0 3.4 3 0 0 3 3 3 0 Peptidase inhibitor I9 KaiC PF06745.8 EKE40401.1 - 0.091 11.8 0.1 0.094 11.8 0.1 1.1 1 0 0 1 1 1 0 KaiC LRR_5 PF13306.1 EKE40402.1 - 3.3e-76 253.1 34.7 1.2e-27 96.1 4.0 3.5 2 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE40402.1 - 9.4e-33 111.7 23.3 8.3e-08 31.8 0.2 6.4 3 2 4 7 7 7 7 Leucine rich repeat Mucin PF01456.12 EKE40403.1 - 0.73 9.5 6.9 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4200 PF13863.1 EKE40405.1 - 0.0065 16.4 11.9 0.0083 16.0 8.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Laminin_II PF06009.7 EKE40405.1 - 0.011 15.4 8.2 0.016 14.9 5.7 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF1741 PF08427.5 EKE40405.1 - 0.015 14.7 5.7 0.016 14.6 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) PMEI PF04043.10 EKE40405.1 - 0.028 14.3 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor AAA_13 PF13166.1 EKE40405.1 - 0.035 12.5 13.7 0.037 12.5 9.5 1.0 1 0 0 1 1 1 0 AAA domain Phage_int_SAM_5 PF13102.1 EKE40405.1 - 0.11 12.5 6.6 0.08 12.9 3.5 1.5 1 1 0 1 1 1 0 Phage integrase SAM-like domain ATP-synt_F6 PF05511.6 EKE40405.1 - 0.13 12.2 1.6 0.18 11.7 1.1 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Complex1_LYR_2 PF13233.1 EKE40405.1 - 0.14 12.6 5.2 0.62 10.5 3.6 2.0 1 1 0 1 1 1 0 Complex1_LYR-like TPR_MLP1_2 PF07926.7 EKE40405.1 - 0.15 11.8 12.5 0.28 10.9 8.7 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein NAAA-beta PF15508.1 EKE40405.1 - 0.15 12.4 1.5 1.4 9.2 0.1 2.2 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Spore_II_R PF09551.5 EKE40405.1 - 0.25 11.3 5.0 0.39 10.7 3.2 1.5 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Occludin_ELL PF07303.8 EKE40405.1 - 0.33 11.7 6.0 1 10.1 2.4 2.1 2 0 0 2 2 2 0 Occludin homology domain Tweety PF04906.8 EKE40405.1 - 0.38 9.1 3.5 0.45 8.8 2.4 1.1 1 0 0 1 1 1 0 Tweety Rabaptin PF03528.10 EKE40405.1 - 0.43 10.5 12.1 0.42 10.5 7.6 1.6 1 1 0 1 1 1 0 Rabaptin HBS1_N PF08938.5 EKE40405.1 - 0.5 10.5 3.9 0.98 9.5 0.3 2.6 1 1 2 3 3 3 0 HBS1 N-terminus UPF0122 PF04297.9 EKE40405.1 - 0.53 10.3 9.0 0.46 10.5 3.7 2.1 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like IFT46_B_C PF12317.3 EKE40405.1 - 4 6.7 8.8 4.8 6.4 6.1 1.2 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF1664 PF07889.7 EKE40405.1 - 7.9 6.3 10.4 7.7 6.3 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EKE40405.1 - 8.3 5.9 11.8 15 5.0 8.2 1.5 1 1 0 1 1 1 0 IncA protein PAP_assoc PF03828.14 EKE40406.1 - 0.079 12.9 0.8 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 Cid1 family poly A polymerase HATPase_c_4 PF13749.1 EKE40407.1 - 0.0032 17.2 0.1 0.0097 15.6 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent DNA helicase recG C-terminal Ribonuclease_T2 PF00445.13 EKE40408.1 - 4.9e-30 104.5 1.6 6.2e-30 104.2 1.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family zf-C3Hc3H PF13891.1 EKE40408.1 - 0.0003 20.7 0.7 0.0003 20.7 0.5 2.1 2 0 0 2 2 2 1 Potential DNA-binding domain Alpha_kinase PF02816.13 EKE40409.1 - 2.4e-41 141.5 4.7 4.6e-41 140.5 3.3 1.5 1 0 0 1 1 1 1 Alpha-kinase family Vps26 PF03643.10 EKE40410.1 - 2.1e-42 144.8 0.4 2.5e-42 144.5 0.3 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 WD40 PF00400.27 EKE40411.1 - 2.8e-43 144.2 14.3 8.3e-11 41.3 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EKE40411.1 - 0.00056 18.1 1.6 0.8 7.7 0.0 3.8 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EKE40411.1 - 0.018 13.3 0.0 0.096 10.9 0.0 2.0 1 1 0 2 2 2 0 Cytochrome D1 heme domain DUF3312 PF11768.3 EKE40411.1 - 0.036 12.2 0.0 0.051 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) YtxC PF08812.6 EKE40411.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 YtxC-like family DUF788 PF05620.6 EKE40412.1 - 0.049 13.4 0.6 0.094 12.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Ras PF00071.17 EKE40414.1 - 2.3e-50 170.1 0.2 2.6e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40414.1 - 7e-19 68.4 0.1 8.9e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40414.1 - 2.7e-13 49.5 0.2 3.3e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE40414.1 - 4.8e-06 26.5 0.1 1.6e-05 24.8 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE40414.1 - 1.6e-05 24.3 0.2 0.00092 18.6 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE40414.1 - 7.7e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE40414.1 - 0.00058 19.0 0.1 0.00069 18.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EKE40414.1 - 0.0017 17.8 0.1 0.0051 16.3 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EKE40414.1 - 0.06 13.1 0.0 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 Dynamin family PglZ PF08665.7 EKE40414.1 - 0.063 12.9 0.1 0.22 11.1 0.0 1.6 1 1 1 2 2 2 0 PglZ domain Arf PF00025.16 EKE40415.1 - 1.6e-24 86.0 0.0 2.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EKE40415.1 - 8.8e-10 38.2 0.3 1.1e-09 37.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40415.1 - 1.5e-09 38.3 0.0 2.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EKE40415.1 - 1.6e-09 36.9 1.3 4e-09 35.6 0.6 1.7 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EKE40415.1 - 9e-08 31.5 0.1 1.1e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE40415.1 - 0.0033 17.3 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE40415.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EKE40415.1 - 0.055 12.4 1.6 2 7.3 0.2 2.1 1 1 1 2 2 2 0 Septin XPG_I PF00867.13 EKE40417.1 - 1.7e-22 79.2 0.1 5.5e-22 77.6 0.1 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EKE40417.1 - 4.5e-16 58.9 0.4 8.2e-15 54.9 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EKE40417.1 - 0.0001 21.9 0.1 0.00088 18.8 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.15 EKE40417.1 - 0.00082 19.5 0.1 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold PPTA PF01239.17 EKE40418.1 - 6.8e-28 94.8 13.0 2.1e-08 33.1 0.5 4.7 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat Atg14 PF10186.4 EKE40422.1 - 0.68 8.8 15.5 0.98 8.3 10.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EKE40422.1 - 1.5 8.7 18.3 0.7 9.8 2.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Cauli_DNA-bind PF03310.8 EKE40422.1 - 4.7 7.0 10.9 3 7.7 5.6 2.0 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Sel1 PF08238.7 EKE40423.1 - 6.7e-38 128.2 3.8 2.2e-10 40.8 0.0 5.5 6 0 0 6 6 5 5 Sel1 repeat TPR_8 PF13181.1 EKE40423.1 - 0.00014 21.4 2.4 0.82 9.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKE40423.1 - 0.0002 21.0 2.4 4 7.6 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EKE40423.1 - 0.00022 21.3 2.9 0.0011 19.0 0.1 3.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EKE40423.1 - 0.00022 21.4 0.2 0.64 10.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKE40423.1 - 0.0009 18.7 1.5 9.7 5.9 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKE40423.1 - 0.0066 16.0 3.2 1.4 8.6 0.6 3.9 2 1 3 5 5 5 2 TPR repeat TPR_6 PF13174.1 EKE40423.1 - 0.012 16.0 0.3 56 4.5 0.0 4.2 6 0 0 6 6 4 0 Tetratricopeptide repeat PPR PF01535.15 EKE40423.1 - 0.048 13.6 1.3 29 4.9 0.0 3.7 4 0 0 4 4 4 0 PPR repeat Ank_2 PF12796.2 EKE40423.1 - 0.053 13.8 0.9 0.41 11.0 0.4 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) DUF2786 PF10979.3 EKE40423.1 - 0.069 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) PPR_2 PF13041.1 EKE40423.1 - 0.075 13.0 0.1 19 5.3 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family FANCL_C PF11793.3 EKE40424.1 - 5.1e-05 23.1 7.6 0.00017 21.5 4.6 2.5 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EKE40424.1 - 0.00048 19.9 10.6 0.00048 19.9 7.4 3.2 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EKE40424.1 - 0.0037 17.3 7.8 0.011 15.8 5.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EKE40424.1 - 0.028 14.2 4.8 0.069 12.9 3.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EKE40424.1 - 0.33 10.7 14.5 0.035 13.8 4.2 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EKE40424.1 - 2.5 8.1 20.1 0.15 12.0 8.6 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EKE40424.1 - 4.4 7.4 13.3 0.92 9.5 6.2 2.2 2 0 0 2 2 2 0 RING-variant domain Ras PF00071.17 EKE40425.1 - 9.3e-54 181.1 0.0 1.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40425.1 - 5.8e-13 49.3 0.0 8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40425.1 - 9e-10 38.0 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE40425.1 - 0.00029 20.0 0.0 0.00038 19.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE40425.1 - 0.0037 16.7 0.1 0.0087 15.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SF3b10 PF07189.6 EKE40426.1 - 3.6e-34 116.4 0.0 4.3e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Aa_trans PF01490.13 EKE40427.1 - 5e-22 77.9 34.9 8e-22 77.2 24.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EKE40427.1 - 6.7e-10 38.0 42.8 6.7e-10 38.0 29.6 1.8 2 0 0 2 2 2 1 Amino acid permease F-box PF00646.28 EKE40430.1 - 7.8e-05 22.2 0.0 0.00026 20.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKE40430.1 - 0.00024 20.7 0.1 0.0025 17.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like Tmemb_185A PF10269.4 EKE40430.1 - 0.00097 18.8 4.4 0.00097 18.8 3.0 3.7 2 1 2 4 4 4 1 Transmembrane Fragile-X-F protein F-box-like_2 PF13013.1 EKE40430.1 - 0.0031 17.2 0.4 0.0086 15.7 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain RVP PF00077.15 EKE40430.1 - 0.1 12.5 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RhoGAP PF00620.22 EKE40431.1 - 3.8e-25 88.2 0.0 6.7e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Sad1_UNC PF07738.8 EKE40432.1 - 8.4e-18 64.4 0.8 2.3e-17 63.0 0.5 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 EKE40432.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Ribosomal_S18 PF01084.15 EKE40432.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.4 3 0 0 3 3 3 0 Ribosomal protein S18 7TMR-HDED PF07697.6 EKE40432.1 - 0.55 9.9 11.7 0.18 11.5 2.3 2.4 1 1 1 2 2 2 0 7TM-HD extracellular RasGAP PF00616.14 EKE40433.1 - 9.4e-10 38.4 9.9 0.00011 21.8 2.1 3.3 2 1 1 3 3 3 3 GTPase-activator protein for Ras-like GTPase UBA PF00627.26 EKE40434.1 - 9.9e-06 25.2 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain DUF1751 PF08551.5 EKE40434.1 - 0.00013 22.2 5.0 0.00013 22.2 3.5 2.3 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) UBA_4 PF14555.1 EKE40434.1 - 0.00023 20.6 0.7 0.00062 19.2 0.5 1.7 1 0 0 1 1 1 1 UBA-like domain Phtf-FEM1B_bdg PF12129.3 EKE40434.1 - 3.4 6.9 6.9 2.6 7.3 3.6 1.7 1 1 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Rhomboid PF01694.17 EKE40434.1 - 4.1 7.4 12.0 14 5.7 8.3 2.0 1 1 0 1 1 1 0 Rhomboid family SRF-TF PF00319.13 EKE40435.1 - 2.4e-19 68.2 0.5 3.9e-19 67.6 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Vps35 PF03635.12 EKE40436.1 - 3.3e-25 88.3 24.1 1.3e-11 43.4 6.9 3.7 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 35 Phage_Capsid_P3 PF09018.6 EKE40436.1 - 0.19 10.2 0.0 0.31 9.5 0.0 1.3 1 0 0 1 1 1 0 P3 major capsid protein ATG27 PF09451.5 EKE40437.1 - 5.7e-13 48.6 0.5 9e-13 48.0 0.3 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EKE40437.1 - 2e-08 33.5 0.1 5e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Spin-Ssty PF02513.12 EKE40437.1 - 0.099 12.2 0.7 0.24 11.0 0.5 1.6 1 0 0 1 1 1 0 Spin/Ssty Family WD40 PF00400.27 EKE40438.1 - 5.8e-06 25.9 1.6 0.00021 21.0 0.2 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat YmzC PF14157.1 EKE40438.1 - 0.0089 15.8 0.3 0.024 14.4 0.2 1.8 1 0 0 1 1 1 1 YmzC-like protein RRM_1 PF00076.17 EKE40439.1 - 3.4e-06 26.5 0.1 6.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40439.1 - 0.0018 18.2 0.1 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 EKE40440.1 - 2.9e-41 141.4 0.0 8.1e-39 133.4 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EKE40440.1 - 7.6e-34 116.5 0.3 1.4e-33 115.6 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EKE40440.1 - 8.7e-13 48.2 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DNA_processg_A PF02481.10 EKE40442.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A Med15 PF09606.5 EKE40443.1 - 0.052 11.7 0.7 0.055 11.6 0.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal COQ9 PF08511.6 EKE40443.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 COQ9 WD40 PF00400.27 EKE40444.1 - 7e-06 25.7 0.0 0.0014 18.4 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat LRR_4 PF12799.2 EKE40444.1 - 7.2e-06 25.5 9.3 0.0079 15.8 1.6 4.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) ENTH PF01417.15 EKE40444.1 - 0.0013 18.5 0.3 0.0057 16.5 0.1 2.2 2 0 0 2 2 2 1 ENTH domain Recep_L_domain PF01030.19 EKE40444.1 - 0.015 15.2 0.3 1.3 9.0 0.0 3.0 2 0 0 2 2 2 0 Receptor L domain LRR_6 PF13516.1 EKE40444.1 - 2.7 8.3 9.3 9.4 6.6 0.1 4.6 4 1 0 4 4 4 0 Leucine Rich repeat Matrilin_ccoil PF10393.4 EKE40444.1 - 6 6.3 9.7 7.1 6.0 0.0 3.8 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin E1-E2_ATPase PF00122.15 EKE40446.1 - 1.7e-15 56.7 0.0 1.7e-15 56.7 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EKE40446.1 - 4.3e-12 46.6 0.0 1.1e-11 45.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE40446.1 - 9.7e-12 45.7 5.3 1.3e-09 38.8 3.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE40446.1 - 7.6e-11 41.8 0.0 3.5e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit AAA_13 PF13166.1 EKE40447.1 - 0.0031 16.0 41.0 0.0031 16.0 28.4 2.2 1 1 1 2 2 2 1 AAA domain SlyX PF04102.7 EKE40447.1 - 0.015 15.6 5.1 0.015 15.6 3.5 5.4 3 1 2 5 5 5 0 SlyX Fis1_TPR_C PF14853.1 EKE40447.1 - 0.25 11.2 8.9 2 8.3 0.2 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Reo_sigmaC PF04582.7 EKE40447.1 - 1.1 8.3 12.8 0.039 13.1 1.5 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EKE40447.1 - 2.4 7.9 66.7 0.065 12.9 18.1 3.7 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein EF-hand_6 PF13405.1 EKE40448.1 - 9.4e-22 74.9 2.2 0.0022 17.7 0.0 6.2 6 0 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.27 EKE40448.1 - 2.6e-19 66.9 3.1 0.0034 16.5 0.0 6.2 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.1 EKE40448.1 - 1.3e-15 57.2 2.8 0.038 14.1 0.0 5.2 3 2 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EKE40448.1 - 1.5e-10 39.9 0.4 0.073 12.4 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EKE40448.1 - 8.8e-08 31.6 6.4 0.35 10.5 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_10 PF14788.1 EKE40448.1 - 7.5e-06 25.5 2.2 0.075 12.7 0.2 4.3 5 0 0 5 5 5 2 EF hand SPARC_Ca_bdg PF10591.4 EKE40448.1 - 1.5e-05 25.0 1.9 0.00085 19.3 0.1 3.3 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKE40448.1 - 0.086 12.5 0.5 11 5.8 0.2 3.1 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Histone PF00125.19 EKE40449.1 - 7.3e-08 32.4 0.1 1.6e-07 31.2 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 FG-GAP_2 PF14312.1 EKE40450.1 - 1.2e-05 25.1 3.8 0.28 11.2 0.0 4.2 4 0 0 4 4 4 3 FG-GAP repeat VHS PF00790.14 EKE40451.1 - 2.7e-05 23.8 1.4 5.7e-05 22.7 0.2 2.0 1 1 0 2 2 2 1 VHS domain Innate_immun PF12782.2 EKE40451.1 - 0.58 9.3 2.1 0.75 8.9 1.5 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family bZIP_2 PF07716.10 EKE40453.1 - 2.3e-06 27.3 6.2 2.3e-06 27.3 4.3 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EKE40453.1 - 0.00093 19.1 18.5 0.001 18.9 9.5 2.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EKE40453.1 - 0.0041 17.3 8.7 0.0041 17.3 6.0 1.7 2 1 0 2 2 2 1 bZIP Maf transcription factor Nbl1_Borealin_N PF10444.4 EKE40453.1 - 0.0077 15.5 1.4 0.018 14.4 1.0 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Y_phosphatase2 PF03162.8 EKE40453.1 - 0.029 13.7 2.0 0.042 13.2 1.4 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF342 PF03961.8 EKE40453.1 - 0.71 8.2 9.9 0.81 8.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Poxvirus_B22R_N PF13169.1 EKE40453.1 - 1.2 9.3 8.4 7.6 6.7 0.1 2.5 1 1 1 2 2 2 0 Poxvirus B22R protein N-terminal zf-DHHC PF01529.15 EKE40456.1 - 2.8e-33 114.7 8.7 2.8e-33 114.7 6.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2732 PF10809.3 EKE40456.1 - 0.15 11.6 0.1 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Synaptobrevin PF00957.16 EKE40457.1 - 4.4e-13 48.6 1.4 1e-12 47.4 0.9 1.6 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EKE40457.1 - 2.1e-11 43.1 0.1 3.8e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain COG2 PF06148.6 EKE40457.1 - 0.0069 16.2 0.7 0.12 12.2 0.2 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 RRM_1 PF00076.17 EKE40458.1 - 7.1e-21 73.6 0.1 1e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40458.1 - 1.3e-19 69.7 0.2 4.8e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40458.1 - 8e-14 51.3 0.1 2.8e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EKE40458.1 - 6.5e-11 41.7 0.5 1.2e-10 40.8 0.4 1.4 1 0 0 1 1 1 1 Surp module Nup35_RRM_2 PF14605.1 EKE40458.1 - 1.6e-07 30.9 0.0 0.00014 21.5 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EKE40458.1 - 4.3e-05 23.3 5.0 0.057 13.2 0.1 3.2 2 1 1 3 3 3 2 RNA binding motif BRAP2 PF07576.7 EKE40458.1 - 0.039 13.5 3.5 0.24 10.9 0.1 2.8 3 0 0 3 3 3 0 BRCA1-associated protein 2 Rotamase_2 PF13145.1 EKE40458.1 - 0.13 12.9 2.9 1.8 9.2 0.6 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain LSM PF01423.17 EKE40459.1 - 4.6e-15 54.9 2.8 6.2e-15 54.5 2.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKE40459.1 - 0.00038 20.3 0.2 0.0006 19.6 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain His_Phos_2 PF00328.17 EKE40460.1 - 2.4e-28 99.4 3.5 2.9e-28 99.1 2.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SRP54 PF00448.17 EKE40461.1 - 9.8e-78 260.1 1.5 1.9e-77 259.1 0.6 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EKE40461.1 - 1.9e-21 76.2 2.0 1.9e-21 76.2 1.4 3.1 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 EKE40461.1 - 1.3e-13 50.7 2.6 3.6e-13 49.3 1.8 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EKE40461.1 - 5.1e-08 32.5 0.1 1.5e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EKE40461.1 - 1.6e-06 27.8 0.4 5.4e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EKE40461.1 - 6.4e-05 22.8 0.1 0.00018 21.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain ArgK PF03308.11 EKE40461.1 - 0.00014 20.7 0.2 0.00073 18.3 0.1 2.2 3 0 0 3 3 3 1 ArgK protein CbiA PF01656.18 EKE40461.1 - 0.00034 20.0 0.2 0.0019 17.6 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EKE40461.1 - 0.0011 18.1 0.2 0.0032 16.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin SRPRB PF09439.5 EKE40461.1 - 0.0026 16.9 1.5 0.85 8.8 0.0 3.2 4 0 0 4 4 4 1 Signal recognition particle receptor beta subunit APS_kinase PF01583.15 EKE40461.1 - 0.0051 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase 6PF2K PF01591.13 EKE40461.1 - 0.0066 15.5 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Thymidylate_kin PF02223.12 EKE40461.1 - 0.025 13.9 1.2 0.18 11.1 0.1 2.5 2 0 0 2 2 2 0 Thymidylate kinase Arf PF00025.16 EKE40461.1 - 0.032 13.4 0.1 0.1 11.7 0.0 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_30 PF13604.1 EKE40461.1 - 0.038 13.5 0.1 0.038 13.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EKE40461.1 - 0.041 14.0 0.1 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2209 PF09974.4 EKE40461.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_10 PF12846.2 EKE40461.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain ATP_bind_1 PF03029.12 EKE40461.1 - 0.048 13.2 0.4 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EKE40461.1 - 0.048 14.4 0.1 0.24 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2683 PF10884.3 EKE40461.1 - 0.058 13.3 0.3 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) AAA PF00004.24 EKE40461.1 - 0.075 13.2 4.4 0.55 10.4 0.3 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EKE40461.1 - 0.1 11.2 1.0 2.7 6.5 0.0 2.4 1 1 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.1 EKE40461.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKE40461.1 - 0.14 12.0 0.1 0.58 10.1 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Kinesin-relat_1 PF12711.2 EKE40461.1 - 0.88 10.0 10.0 0.1 13.0 0.9 3.3 4 0 0 4 4 4 0 Kinesin motor DS PF01916.12 EKE40463.1 - 2e-98 329.2 0.3 2.2e-98 329.0 0.2 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase HEAT PF02985.17 EKE40464.1 - 3.3e-06 26.7 0.0 12 6.2 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat Arm PF00514.18 EKE40464.1 - 0.013 15.3 1.1 5.5 6.9 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EKE40464.1 - 0.013 15.7 0.0 1.3 9.3 0.0 3.6 2 1 1 3 3 3 0 HEAT repeats Vac14_Fab1_bd PF12755.2 EKE40464.1 - 2 8.8 20.4 1.5 9.3 0.2 7.2 8 1 0 8 8 8 0 Vacuolar 14 Fab1-binding region RhoGEF PF00621.15 EKE40465.1 - 1.4e-08 34.8 4.0 1.4e-08 34.8 2.8 2.6 2 1 0 2 2 2 1 RhoGEF domain zf-MIZ PF02891.15 EKE40466.1 - 1e-17 63.3 4.0 2.1e-17 62.3 2.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EKE40466.1 - 5.7e-05 22.5 3.2 0.00016 21.1 2.2 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 EKE40466.1 - 0.034 13.6 1.6 0.12 11.8 1.1 2.0 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_5 PF14634.1 EKE40466.1 - 0.27 11.0 3.9 0.64 9.7 2.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EKE40466.1 - 0.94 9.3 4.5 4.2 7.2 3.3 2.0 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 EKE40466.1 - 2.6 8.1 7.2 0.79 9.7 2.3 2.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prp19_bind PF06991.6 EKE40467.1 - 1.3e-30 106.6 28.7 1.7e-30 106.2 19.9 1.0 1 0 0 1 1 1 1 Splicing factor, Prp19-binding domain UCH_1 PF13423.1 EKE40467.1 - 0.37 10.1 5.6 0.43 9.9 3.9 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2852 PF11014.3 EKE40467.1 - 9.7 6.1 12.7 0.32 10.9 2.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2852) Peptidase_M49 PF03571.10 EKE40469.1 - 1.2e-160 535.2 0.3 1.5e-160 534.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M49 DUF3826 PF12875.2 EKE40469.1 - 0.15 11.7 6.4 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3826) CitMHS PF03600.11 EKE40470.1 - 1.5e-17 63.1 0.0 9.6e-15 54.0 0.0 2.8 1 1 2 3 3 3 2 Citrate transporter TrkA_C PF02080.16 EKE40470.1 - 0.00097 18.6 0.0 0.0029 17.1 0.0 1.8 2 0 0 2 2 2 1 TrkA-C domain WW PF00397.21 EKE40471.1 - 0.045 13.6 0.9 0.27 11.1 0.1 2.7 3 0 0 3 3 3 0 WW domain RabGAP-TBC PF00566.13 EKE40472.1 - 4.1e-24 85.2 9.6 7.8e-24 84.3 6.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PMC2NT PF08066.7 EKE40472.1 - 4.4 7.6 6.8 19 5.6 0.1 3.6 3 0 0 3 3 3 0 PMC2NT (NUC016) domain HrcA PF01628.16 EKE40473.1 - 0.029 13.9 0.6 0.05 13.1 0.3 1.3 1 1 0 1 1 1 0 HrcA protein C terminal domain HTH_19 PF12844.2 EKE40473.1 - 0.039 14.0 0.6 0.092 12.8 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Acetyltransf_2 PF00797.12 EKE40473.1 - 0.081 12.4 0.9 10 5.5 0.0 2.6 2 1 1 3 3 3 0 N-acetyltransferase Thioredoxin PF00085.15 EKE40474.1 - 5.5e-15 54.9 0.0 6.3e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE40474.1 - 1.3e-05 25.3 0.2 0.00024 21.2 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EKE40474.1 - 9.2e-05 22.1 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EKE40474.1 - 0.0016 18.4 2.2 0.26 11.2 0.3 2.2 1 1 1 2 2 2 2 Thioredoxin PhnA_Zn_Ribbon PF08274.7 EKE40474.1 - 0.0082 15.9 0.7 0.012 15.3 0.5 1.2 1 0 0 1 1 1 1 PhnA Zinc-Ribbon Thioredoxin_7 PF13899.1 EKE40474.1 - 0.019 14.9 0.1 0.033 14.2 0.0 1.4 2 0 0 2 2 2 0 Thioredoxin-like DUF836 PF05768.9 EKE40474.1 - 0.031 14.5 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 EKE40474.1 - 0.038 13.5 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF2847 PF11009.3 EKE40474.1 - 0.04 13.4 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Thioredoxin_8 PF13905.1 EKE40474.1 - 0.061 13.4 0.2 0.16 12.0 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 EKE40474.1 - 0.094 12.4 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DUF953 PF06110.6 EKE40474.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) ATP-synt_C PF00137.16 EKE40475.1 - 2.4e-21 75.3 28.9 2.1e-13 49.9 8.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.19 EKE40475.1 - 0.02 14.4 6.4 0.022 14.3 2.2 2.4 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L G0-G1_switch_2 PF15103.1 EKE40475.1 - 1 9.5 5.3 0.35 11.0 1.0 2.1 2 1 1 3 3 3 0 G0/G1 switch protein 2 Tropomyosin_1 PF12718.2 EKE40476.1 - 0.0092 15.8 26.8 0.0092 15.8 18.6 2.1 1 1 1 2 2 2 1 Tropomyosin like HlyD PF00529.15 EKE40476.1 - 0.03 13.6 9.7 0.034 13.4 6.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Myosin_tail_1 PF01576.14 EKE40476.1 - 0.046 11.4 31.8 0.12 10.1 22.1 1.5 1 1 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.4 EKE40476.1 - 0.1 12.4 35.5 1.5 8.6 7.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.1 EKE40476.1 - 0.2 9.3 19.0 0.24 9.0 13.2 1.0 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EKE40476.1 - 0.23 11.6 22.2 0.058 13.5 7.1 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EKE40476.1 - 0.27 10.2 34.8 0.085 11.8 10.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Taxilin PF09728.4 EKE40476.1 - 0.41 9.7 36.5 1.5 7.8 24.4 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Filament PF00038.16 EKE40476.1 - 0.52 9.7 29.3 2.2 7.6 6.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 EKE40476.1 - 0.72 9.7 20.2 2.2 8.2 3.5 3.9 2 2 1 4 4 4 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 EKE40476.1 - 1 9.1 30.4 0.67 9.7 10.9 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec2p PF06428.6 EKE40476.1 - 1.2 9.0 26.4 1.9 8.3 2.6 3.2 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF869 PF05911.6 EKE40476.1 - 1.3 7.2 27.9 1.5 6.9 19.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2968 PF11180.3 EKE40476.1 - 2.1 7.6 21.9 5.8 6.2 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4298 PF14131.1 EKE40476.1 - 2.4 8.1 15.6 3.5 7.5 0.3 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4298) DNA_topoisoIV PF00521.15 EKE40476.1 - 2.4 6.9 18.2 2.9 6.6 12.6 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A GAS PF13851.1 EKE40476.1 - 3.7 6.6 34.9 0.51 9.5 11.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EKE40476.1 - 4.3 7.2 34.7 15 5.4 16.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cob_adeno_trans PF01923.13 EKE40476.1 - 4.6 7.0 10.1 1.2e+02 2.3 7.0 2.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF4140 PF13600.1 EKE40476.1 - 4.6 7.7 20.1 3.6 8.0 4.2 3.7 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) zf-C4pol PF14260.1 EKE40476.1 - 8.1 6.5 9.1 2.4 8.2 2.5 2.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta IFT57 PF10498.4 EKE40476.1 - 8.8 4.9 28.1 0.29 9.8 10.3 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 THOC7 PF05615.8 EKE40476.1 - 9.2 6.5 33.0 2.5 8.3 10.5 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 HAUS6_N PF14661.1 EKE40476.1 - 9.9 5.4 22.0 6.6 6.0 7.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DENN PF02141.16 EKE40477.1 - 2e-19 70.0 13.9 4.4e-18 65.6 6.0 3.3 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 EKE40477.1 - 4e-07 29.9 0.4 4e-07 29.9 0.3 2.9 3 0 0 3 3 3 1 uDENN domain DUF4187 PF13821.1 EKE40478.1 - 3.8e-06 26.3 0.3 8.9e-06 25.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 EKE40478.1 - 0.00016 21.6 3.2 0.0043 17.1 0.4 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EKE40478.1 - 0.12 12.7 5.8 3.4 8.1 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EKE40478.1 - 0.2 11.4 4.8 7.7 6.3 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EKE40478.1 - 0.34 10.8 4.6 0.44 10.5 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RRF PF01765.14 EKE40479.1 - 1.4 8.3 10.2 0.92 8.9 6.1 1.4 1 1 0 1 1 1 0 Ribosome recycling factor FliX PF10768.4 EKE40479.1 - 6.4 6.9 10.6 0.9 9.7 4.3 1.8 1 1 1 2 2 2 0 Class II flagellar assembly regulator FtsJ PF01728.14 EKE40480.1 - 3.6e-52 176.9 0.0 6.4e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 EKE40480.1 - 8.4e-37 126.7 25.1 8.4e-37 126.7 17.4 3.5 2 2 1 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EKE40480.1 - 5.6e-21 74.7 19.7 5.6e-21 74.7 13.7 5.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) PP2C PF00481.16 EKE40481.1 - 1.7e-35 122.6 0.0 2.2e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE40481.1 - 7.9e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE40481.1 - 0.0022 17.7 0.1 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) TatD_DNase PF01026.16 EKE40484.1 - 9.2e-39 133.1 0.0 1.1e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Radical_SAM PF04055.16 EKE40484.1 - 0.0074 16.4 0.3 0.84 9.7 0.0 2.4 2 1 0 2 2 2 2 Radical SAM superfamily Pterin_bind PF00809.17 EKE40484.1 - 0.066 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Pterin binding enzyme DUF4606 PF15379.1 EKE40484.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Tau95 PF09734.4 EKE40485.1 - 1.3e-05 24.6 0.5 1.9e-05 24.1 0.3 1.4 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Cys_rich_KTR PF14205.1 EKE40485.1 - 0.074 12.5 2.0 0.12 11.8 0.5 2.1 2 0 0 2 2 2 0 Cysteine-rich KTR LRR_5 PF13306.1 EKE40486.1 - 4.8e-133 436.9 78.7 3.8e-39 133.3 5.2 5.4 1 1 5 6 6 6 6 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE40486.1 - 7.6e-41 137.6 26.9 5.9e-09 35.5 0.0 9.5 3 2 9 12 12 12 11 Leucine rich repeat LpxB PF02684.10 EKE40487.1 - 0.065 11.8 0.1 0.065 11.8 0.1 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Sec7 PF01369.15 EKE40488.1 - 2.7e-25 89.1 9.6 2.7e-25 89.1 6.6 4.1 5 0 0 5 5 5 1 Sec7 domain Nol1_Nop2_Fmu PF01189.12 EKE40489.1 - 1.9e-51 175.1 0.0 6.6e-31 107.7 0.0 2.5 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EKE40489.1 - 5.6e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EKE40489.1 - 0.009 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SNF2_N PF00176.18 EKE40490.1 - 3.1e-65 219.9 0.0 6.2e-65 218.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE40490.1 - 6.7e-13 48.3 0.0 1.9e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TLD PF07534.11 EKE40491.1 - 0.0001 22.3 0.4 0.00021 21.2 0.1 1.7 2 0 0 2 2 2 1 TLD DEAD PF00270.24 EKE40492.1 - 3.3e-43 147.0 2.6 1.4e-42 145.1 0.0 3.1 3 1 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE40492.1 - 2e-21 75.6 0.1 5.4e-21 74.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKE40492.1 - 0.00012 20.9 0.1 0.00032 19.6 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EKE40492.1 - 3.3 6.9 17.6 0.45 9.7 0.8 4.5 4 2 0 4 4 4 0 SecA DEAD-like domain Fcf1 PF04900.7 EKE40493.1 - 4.3e-38 129.4 0.8 6.2e-38 128.9 0.6 1.2 1 0 0 1 1 1 1 Fcf1 RhoGAP PF00620.22 EKE40494.1 - 2.2e-30 105.2 0.0 6.1e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain UCR_TM PF02921.9 EKE40494.1 - 1 9.6 2.4 0.84 9.9 0.2 2.1 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region WD40 PF00400.27 EKE40495.1 - 1.7e-32 110.1 13.3 3.8e-10 39.2 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat COX5B PF01215.14 EKE40495.1 - 0.0043 16.7 0.1 0.019 14.6 0.0 2.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DPBB_1 PF03330.13 EKE40496.1 - 1.2e-06 28.4 0.8 1.2e-05 25.2 0.1 2.8 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PP2C PF00481.16 EKE40497.1 - 4.7e-65 219.5 0.0 1.1e-64 218.3 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE40497.1 - 2.4e-08 33.6 0.0 5.6e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE40497.1 - 0.00085 19.0 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Lactamase_B PF00753.22 EKE40499.1 - 2.6e-23 82.7 0.2 3e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE40499.1 - 4.4e-06 26.3 0.1 7.5e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EKE40500.1 - 1.1e-05 24.8 15.6 1.1e-05 24.8 10.8 1.9 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Med15 PF09606.5 EKE40500.1 - 1.5 6.8 46.7 2 6.5 32.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Chorein_N PF12624.2 EKE40501.1 - 7.7e-22 77.0 5.1 1.7e-21 75.9 0.7 3.7 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EKE40501.1 - 0.00038 20.5 0.0 0.0039 17.3 0.0 2.6 3 0 0 3 3 3 1 ATG C terminal domain KTI12 PF08433.5 EKE40502.1 - 6.1e-70 235.5 0.2 6.8e-70 235.3 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EKE40502.1 - 3.1e-10 40.0 0.0 5.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE40502.1 - 2.7e-08 34.1 0.1 4.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE40502.1 - 2.1e-07 31.7 0.0 3.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKE40502.1 - 0.00091 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 EKE40502.1 - 0.0028 16.7 0.3 0.027 13.5 0.2 2.0 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_28 PF13521.1 EKE40502.1 - 0.0039 17.1 0.0 0.0059 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EKE40502.1 - 0.0047 15.8 0.0 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Endotoxin_C PF03944.9 EKE40502.1 - 0.006 16.6 0.6 0.34 11.0 0.1 2.3 2 0 0 2 2 2 1 delta endotoxin AAA_16 PF13191.1 EKE40502.1 - 0.0061 16.5 0.0 0.21 11.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EKE40502.1 - 0.0081 16.1 0.1 0.03 14.2 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF2075 PF09848.4 EKE40502.1 - 0.032 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EKE40502.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 EKE40502.1 - 0.05 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Miro PF08477.8 EKE40502.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein AAA PF00004.24 EKE40502.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TFIIE_alpha PF02002.12 EKE40503.1 - 0.057 12.9 5.8 0.066 12.7 2.8 2.1 1 1 0 1 1 1 0 TFIIE alpha subunit Peptidase_S41 PF03572.13 EKE40505.1 - 3.4e-05 23.3 0.0 8.5e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 Shisa PF13908.1 EKE40505.1 - 0.00062 19.9 4.4 0.0014 18.8 3.1 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mid2 PF04478.7 EKE40505.1 - 0.00076 18.9 3.0 0.0022 17.4 2.1 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4064 PF13273.1 EKE40505.1 - 0.011 15.7 0.3 0.03 14.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) RhoGAP PF00620.22 EKE40506.1 - 3.1e-21 75.5 2.6 3.9e-21 75.2 0.2 2.3 2 0 0 2 2 2 1 RhoGAP domain zf-RING_2 PF13639.1 EKE40506.1 - 0.007 16.1 5.0 0.037 13.8 3.5 2.3 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.17 EKE40506.1 - 0.016 14.9 12.4 0.041 13.6 8.6 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PQQ_2 PF13360.1 EKE40506.1 - 0.019 14.4 0.0 0.27 10.6 0.0 2.3 1 1 1 2 2 2 0 PQQ-like domain PHD PF00628.24 EKE40506.1 - 0.041 13.5 6.4 0.12 12.1 4.5 1.8 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EKE40506.1 - 0.044 13.5 6.8 0.098 12.3 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 MVL PF12151.3 EKE40506.1 - 0.18 11.5 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 Mannan-binding protein PQQ PF01011.16 EKE40506.1 - 0.2 11.2 1.4 16 5.2 0.1 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat C1_1 PF00130.17 EKE40507.1 - 0.017 14.8 5.0 0.059 13.0 3.5 2.0 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HSP70 PF00012.15 EKE40509.1 - 3.2e-69 233.4 10.2 4e-69 233.1 7.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE40509.1 - 1.7e-08 33.4 0.2 1.1e-07 30.8 0.1 2.1 1 1 0 1 1 1 1 MreB/Mbl protein StbA PF06406.6 EKE40509.1 - 0.0004 19.4 0.7 0.0085 15.0 0.1 2.6 1 1 0 2 2 2 1 StbA protein Dpoe2NT PF12213.3 EKE40509.1 - 0.012 15.4 0.8 4.5 7.2 0.2 2.9 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal BcrAD_BadFG PF01869.15 EKE40509.1 - 0.036 13.3 0.0 0.16 11.2 0.0 2.1 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3042 PF11240.3 EKE40509.1 - 0.13 12.0 2.8 9.5 6.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) HSF_DNA-bind PF00447.12 EKE40510.1 - 1e-22 80.2 3.4 1e-22 80.2 2.4 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding IncA PF04156.9 EKE40510.1 - 0.22 11.1 6.6 0.34 10.4 4.6 1.2 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EKE40510.1 - 1.3 9.1 8.2 2.2 8.4 5.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UCH PF00443.24 EKE40512.1 - 4.2e-15 55.5 16.2 6e-13 48.5 11.3 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE40512.1 - 7.9e-06 25.5 9.8 0.021 14.2 5.1 3.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase C1_1 PF00130.17 EKE40514.1 - 0.0002 21.0 4.4 0.00041 20.0 3.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) YdjO PF14169.1 EKE40514.1 - 0.049 13.0 2.6 3.1 7.3 0.2 2.7 2 0 0 2 2 2 0 Cold-inducible protein YdjO Prok-RING_1 PF14446.1 EKE40514.1 - 0.1 12.3 8.8 0.088 12.5 4.7 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EKE40514.1 - 0.15 11.7 7.2 0.35 10.6 5.0 1.6 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 EKE40514.1 - 0.21 11.6 3.1 0.52 10.4 2.1 1.6 1 0 0 1 1 1 0 C1-like domain DUF972 PF06156.8 EKE40514.1 - 1.7 9.0 22.4 2.6 8.4 5.5 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CALCOCO1 PF07888.6 EKE40514.1 - 2.2 6.4 35.1 7.6 4.6 24.4 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DNA_pol_A PF00476.15 EKE40515.1 - 7.2e-78 261.8 0.1 7.2e-78 261.8 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family A START PF01852.14 EKE40516.1 - 7.4e-11 41.7 0.1 8.4e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 START domain DnaJ PF00226.26 EKE40517.1 - 2.3e-24 84.9 3.4 4.1e-24 84.0 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EKE40517.1 - 4.6e-24 84.1 7.1 9.4e-21 73.5 0.9 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKE40517.1 - 1.1e-15 57.3 17.5 1.9e-15 56.6 12.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EKE40517.1 - 0.0056 16.3 2.3 0.24 11.0 0.0 2.3 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EKE40517.1 - 0.24 11.7 8.3 0.64 10.4 5.8 1.8 1 0 0 1 1 1 0 Cytochrome c3 DZR PF12773.2 EKE40517.1 - 0.76 9.6 9.6 5.3 6.9 6.8 2.1 1 1 1 2 2 2 0 Double zinc ribbon Sar8_2 PF03058.9 EKE40517.1 - 1.4 9.2 5.7 3.9 7.8 2.5 2.5 3 0 0 3 3 3 0 Sar8.2 family zf-C3HC4_3 PF13920.1 EKE40517.1 - 2.5 7.8 7.2 13 5.5 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Lar_restr_allev PF14354.1 EKE40517.1 - 2.8 8.2 9.5 0.88 9.9 3.2 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar Sep15_SelM PF08806.6 EKE40518.1 - 2.8e-07 30.1 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain SH3_2 PF07653.12 EKE40520.1 - 9.6e-10 37.8 0.1 3.6e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EKE40520.1 - 2.9e-09 36.1 0.1 9.4e-09 34.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EKE40520.1 - 3.6e-08 32.8 1.5 7e-08 31.9 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_3 PF08239.6 EKE40520.1 - 4.4e-05 23.5 0.1 9.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Tetraspannin PF00335.15 EKE40521.1 - 6.8e-05 22.2 14.1 0.00016 20.9 9.9 1.6 1 1 0 1 1 1 1 Tetraspanin family Ycf1 PF05758.7 EKE40521.1 - 0.03 12.0 0.6 0.04 11.6 0.4 1.1 1 0 0 1 1 1 0 Ycf1 EphA2_TM PF14575.1 EKE40521.1 - 0.047 14.0 3.8 7.1 7.1 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF805 PF05656.9 EKE40521.1 - 0.45 10.3 4.2 0.67 9.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) SRF-TF PF00319.13 EKE40522.1 - 1.8e-17 62.3 0.5 2.9e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) OmdA PF13376.1 EKE40522.1 - 0.32 10.6 1.8 0.54 9.9 1.2 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated CFIA_Pcf11 PF11526.3 EKE40522.1 - 2 8.6 5.9 2.1 8.5 0.5 2.4 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 UBX PF00789.15 EKE40523.1 - 1.9e-12 47.0 0.0 5.4e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF1616 PF07760.6 EKE40523.1 - 0.11 11.5 0.5 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Thioesterase PF00975.15 EKE40523.1 - 0.82 9.8 4.7 1.4 9.1 3.3 1.3 1 0 0 1 1 1 0 Thioesterase domain CAF-1_p150 PF11600.3 EKE40523.1 - 1.1 8.5 43.1 1.5 8.1 29.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zip PF02535.17 EKE40523.1 - 3.6 6.5 4.8 6.7 5.6 3.3 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Asp-B-Hydro_N PF05279.6 EKE40523.1 - 7.6 6.2 26.7 12 5.6 18.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UBX PF00789.15 EKE40524.1 - 8.4e-05 22.5 0.0 0.00028 20.8 0.0 1.9 1 0 0 1 1 1 1 UBX domain Parvo_coat PF00740.13 EKE40524.1 - 6.4 5.6 14.3 9.5 5.0 9.9 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RhoGAP PF00620.22 EKE40525.1 - 2.3e-15 56.5 0.1 3.2e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain PP2C_2 PF13672.1 EKE40526.1 - 7.2e-11 41.8 0.0 2e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE40526.1 - 0.0001 22.0 0.0 0.00027 20.7 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Med9 PF07544.8 EKE40527.1 - 0.059 13.1 0.2 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FHIPEP PF00771.15 EKE40529.1 - 0.2 9.9 4.5 0.25 9.6 3.1 1.1 1 0 0 1 1 1 0 FHIPEP family RhoGAP PF00620.22 EKE40531.1 - 6.9e-28 97.1 0.4 3.5e-27 94.9 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain ABC_tran PF00005.22 EKE40533.1 - 1.1e-09 38.7 0.0 1.1e-09 38.7 0.0 2.6 2 1 0 2 2 1 1 ABC transporter AAA_17 PF13207.1 EKE40533.1 - 0.00028 21.7 1.8 0.0084 16.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKE40533.1 - 0.00048 19.6 1.1 0.073 12.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 EKE40533.1 - 0.0031 17.5 7.3 0.0061 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKE40533.1 - 0.0041 17.2 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKE40533.1 - 0.0049 16.8 0.3 0.044 13.7 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EKE40533.1 - 0.018 15.0 1.1 0.039 13.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EKE40533.1 - 0.02 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EKE40533.1 - 0.026 14.5 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EKE40533.1 - 0.05 13.5 0.2 0.05 13.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EKE40533.1 - 0.076 13.5 2.7 0.087 13.3 0.0 2.5 3 1 0 3 3 3 0 Miro-like protein ATP-synt_ab PF00006.20 EKE40533.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EKE40533.1 - 0.087 13.0 0.3 0.4 10.8 0.0 2.3 2 1 0 2 2 2 0 RNA helicase DUF87 PF01935.12 EKE40533.1 - 0.36 10.5 0.0 0.36 10.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF87 NIF3 PF01784.13 EKE40534.1 - 1.8e-62 211.0 0.0 2.2e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) SPA PF08616.5 EKE40535.1 - 4.9e-12 45.5 0.1 1.2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EKE40535.1 - 3.7e-10 38.8 0.8 1.3e-07 30.4 0.0 2.9 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.4 EKE40535.1 - 0.1 11.8 0.2 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) SPRY PF00622.23 EKE40537.1 - 6.7e-12 45.5 0.4 1.8e-11 44.1 0.3 1.8 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 EKE40537.1 - 3e-10 39.6 13.0 3e-10 39.6 9.0 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE40537.1 - 4.7e-07 29.7 17.4 1.2e-06 28.3 12.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE40537.1 - 0.00026 20.6 18.2 0.00075 19.0 12.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE40537.1 - 0.0039 16.9 16.3 0.0039 16.9 11.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EKE40537.1 - 0.023 14.3 16.7 0.056 13.1 11.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.1 EKE40537.1 - 0.066 12.7 9.9 0.091 12.3 5.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EKE40537.1 - 6.6 6.6 13.6 22 5.0 9.4 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TLD PF07534.11 EKE40538.1 - 8.7e-07 29.0 1.9 2.3e-06 27.6 1.4 1.7 1 1 0 1 1 1 1 TLD DUF2436 PF10365.4 EKE40538.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) NYN_YacP PF05991.6 EKE40538.1 - 0.047 13.4 1.1 0.07 12.8 0.8 1.3 1 0 0 1 1 1 0 YacP-like NYN domain Lung_7-TM_R PF06814.8 EKE40539.1 - 0.00062 18.8 31.6 0.0014 17.6 21.9 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EKE40539.1 - 0.02 14.0 43.0 0.047 12.8 29.0 2.2 2 1 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain DUF1192 PF06698.6 EKE40539.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Halogen_Hydrol PF10112.4 EKE40539.1 - 3.7 6.8 10.5 3.2 7.1 0.9 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Dna2 PF08696.6 EKE40540.1 - 1.8e-27 96.0 0.2 4.5e-27 94.7 0.2 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 PDDEXK_1 PF12705.2 EKE40540.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EKE40540.1 - 2.9e-05 24.0 0.1 0.0001 22.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF83 DUF2200 PF09966.4 EKE40540.1 - 0.0023 17.7 0.5 0.0084 15.9 0.1 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2200) DUF911 PF06023.7 EKE40540.1 - 0.023 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) DUF202 PF02656.10 EKE40541.1 - 0.99 9.6 3.7 20 5.4 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF3671 PF12420.3 EKE40541.1 - 4.7 7.2 10.7 0.5 10.3 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function Sigma_reg_N PF13800.1 EKE40541.1 - 5 7.2 6.7 4.4 7.3 0.0 3.2 3 1 0 3 3 3 0 Sigma factor regulator N-terminal LIM PF00412.17 EKE40542.1 - 3.4e-09 36.6 6.5 5.8e-09 35.8 4.5 1.4 1 0 0 1 1 1 1 LIM domain Ku PF02735.11 EKE40542.1 - 0.04 13.3 2.9 0.06 12.7 2.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain DNA_ligase_ZBD PF03119.11 EKE40542.1 - 0.071 12.8 0.0 0.25 11.0 0.0 2.0 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain CENP-Q PF13094.1 EKE40542.1 - 0.077 13.0 2.8 0.1 12.6 1.9 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.4 EKE40542.1 - 0.14 12.3 4.6 0.18 11.9 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-met PF12874.2 EKE40542.1 - 0.14 12.3 6.2 0.18 12.0 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4428 PF14471.1 EKE40542.1 - 0.17 11.6 7.2 0.091 12.5 2.9 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) DUF3530 PF12048.3 EKE40542.1 - 0.18 10.7 1.2 0.23 10.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) RR_TM4-6 PF06459.7 EKE40542.1 - 0.19 11.5 7.6 0.28 11.0 5.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 C1_2 PF03107.11 EKE40542.1 - 0.26 11.4 5.0 0.36 10.9 0.6 2.8 3 1 0 3 3 3 0 C1 domain OrfB_Zn_ribbon PF07282.6 EKE40542.1 - 0.56 9.9 3.8 0.89 9.2 1.6 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EKE40542.1 - 0.72 9.7 6.0 0.57 10.0 2.5 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RhoGAP PF00620.22 EKE40543.1 - 1.7e-17 63.4 0.1 3.2e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MIP PF00230.15 EKE40544.1 - 5.7e-12 45.5 11.3 1.4e-07 31.1 3.0 2.1 1 1 1 2 2 2 2 Major intrinsic protein Vpu PF00558.14 EKE40544.1 - 0.12 11.9 0.0 0.41 10.2 0.0 1.9 1 0 0 1 1 1 0 Vpu protein MFS_1 PF07690.11 EKE40545.1 - 4.8e-35 120.9 17.3 8.5e-22 77.3 0.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM176 PF14851.1 EKE40545.1 - 0.075 12.7 6.9 0.45 10.1 1.0 2.7 2 1 1 3 3 3 0 FAM176 family HMGL-like PF00682.14 EKE40546.1 - 0.029 14.0 0.1 0.029 14.0 0.0 2.3 3 1 0 3 3 3 0 HMGL-like CH PF00307.26 EKE40547.1 - 1.7e-16 60.2 15.0 6.1e-11 42.3 0.5 3.9 4 0 0 4 4 4 2 Calponin homology (CH) domain UFD1 PF03152.9 EKE40548.1 - 9.8e-29 99.7 0.5 1.7e-28 98.9 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-TRAF PF02176.13 EKE40548.1 - 4e-08 33.5 5.9 4e-08 33.5 4.1 3.7 3 1 1 4 4 4 3 TRAF-type zinc finger Lar_restr_allev PF14354.1 EKE40548.1 - 0.00076 19.7 16.9 0.0011 19.1 1.6 4.3 3 2 0 3 3 3 1 Restriction alleviation protein Lar VacJ PF04333.8 EKE40548.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 VacJ like lipoprotein Dynactin_p62 PF05502.8 EKE40548.1 - 4.5 5.9 18.2 4.3 5.9 0.2 3.2 2 1 0 3 3 3 0 Dynactin p62 family zf-C2H2_4 PF13894.1 EKE40548.1 - 8.4 6.9 27.9 2.7 8.5 1.4 6.1 5 1 1 6 6 6 0 C2H2-type zinc finger zf-C3HC4_2 PF13923.1 EKE40549.1 - 2.8 8.0 8.3 1 9.4 1.9 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 EKE40551.1 - 1e-34 119.9 0.1 1.5e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40551.1 - 8e-31 107.0 0.0 1.3e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.19 EKE40551.1 - 1.8e-06 27.6 0.0 4.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain eRF1_1 PF03463.10 EKE40552.1 - 9.2e-20 70.5 0.5 1.8e-19 69.5 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EKE40552.1 - 7.2e-14 52.0 0.5 1.9e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EKE40552.1 - 6.6e-11 42.6 0.1 1.2e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 DUF382 PF04037.8 EKE40553.1 - 2.1e-47 160.1 0.7 5.2e-47 158.8 0.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EKE40553.1 - 8.8e-13 47.4 0.9 1.8e-12 46.4 0.6 1.5 1 0 0 1 1 1 1 PSP PRKCSH_1 PF13015.1 EKE40554.1 - 0.00028 20.3 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 EKE40554.1 - 0.00059 19.1 7.1 0.024 13.8 5.0 2.3 1 1 0 1 1 1 1 Autophagy-related protein 27 MMPL PF03176.10 EKE40554.1 - 0.0057 15.4 0.0 0.0064 15.2 0.0 1.1 1 0 0 1 1 1 1 MMPL family Rifin_STEVOR PF02009.11 EKE40554.1 - 0.048 13.2 0.3 0.057 13.0 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Methyltransf_23 PF13489.1 EKE40555.1 - 2.6e-14 53.2 0.0 3.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE40555.1 - 1e-11 45.1 0.0 1.6e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE40555.1 - 4.3e-10 39.9 0.0 7.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE40555.1 - 7e-10 38.6 0.0 8.3e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKE40555.1 - 9.6e-06 25.9 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE40555.1 - 2.1e-05 25.0 0.0 3.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE40555.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKE40555.1 - 0.00027 20.0 0.0 0.0035 16.4 0.0 2.2 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_24 PF13578.1 EKE40555.1 - 0.00034 21.4 0.0 0.00054 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EKE40555.1 - 0.0015 17.5 0.0 0.0019 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 EKE40555.1 - 0.0058 16.0 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EKE40555.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_8 PF05148.10 EKE40555.1 - 0.043 13.4 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase DUF1632 PF07857.7 EKE40556.1 - 1.6e-60 204.5 10.5 5e-59 199.6 7.3 2.2 1 1 0 1 1 1 1 CEO family (DUF1632) Sugar_transport PF06800.7 EKE40556.1 - 4.5e-09 35.7 20.1 7.9e-08 31.7 3.5 2.9 2 1 0 2 2 2 2 Sugar transport protein ALG3 PF05208.8 EKE40556.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 ALG3 protein WWE PF02825.15 EKE40559.1 - 6.9e-05 22.1 4.8 6.9e-05 22.1 3.3 2.1 2 0 0 2 2 2 1 WWE domain FPL PF09758.4 EKE40560.1 - 2e-38 131.4 7.6 3.3e-38 130.8 3.6 2.6 2 0 0 2 2 2 1 Uncharacterised conserved protein DUF2883 PF11097.3 EKE40560.1 - 0.11 12.6 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2883) CDP-OH_P_transf PF01066.16 EKE40561.1 - 5.7e-19 68.3 9.9 5.7e-19 68.3 6.9 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PqiA PF04403.8 EKE40561.1 - 0.054 13.0 1.8 0.12 11.9 0.4 2.2 1 1 1 3 3 3 0 Paraquat-inducible protein A DUF663 PF04950.7 EKE40562.1 - 1.1e-74 251.0 3.5 1.1e-74 251.0 2.5 2.4 4 0 0 4 4 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EKE40562.1 - 6.1e-28 96.1 0.1 5e-27 93.2 0.0 2.5 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EKE40562.1 - 3.4e-08 33.1 0.0 7e-06 25.6 0.0 3.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EKE40562.1 - 5.6e-06 26.5 0.0 3.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EKE40562.1 - 3.7e-05 23.9 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EKE40562.1 - 9.6e-05 22.2 0.3 0.0003 20.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EKE40562.1 - 0.00021 21.3 0.0 0.00088 19.3 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 EKE40562.1 - 0.00026 21.8 0.0 0.00026 21.8 0.0 3.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EKE40562.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PRK PF00485.13 EKE40562.1 - 0.0017 17.9 0.0 0.0057 16.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 EKE40562.1 - 0.0017 17.8 0.2 0.0095 15.4 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EKE40562.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 EKE40562.1 - 0.0031 18.0 2.1 0.007 16.8 0.0 2.7 2 0 0 2 2 1 1 Miro-like protein Viral_helicase1 PF01443.13 EKE40562.1 - 0.0032 17.0 2.8 0.0039 16.7 0.0 2.5 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EKE40562.1 - 0.0055 16.4 0.5 0.026 14.2 0.0 2.3 3 0 0 3 3 2 1 Part of AAA domain AAA_10 PF12846.2 EKE40562.1 - 0.0062 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EKE40562.1 - 0.0067 16.7 6.2 0.017 15.4 0.0 3.8 3 0 0 3 3 3 1 ABC transporter AAA_14 PF13173.1 EKE40562.1 - 0.0071 16.2 0.0 0.025 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKE40562.1 - 0.0092 16.1 0.0 0.0092 16.1 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.1 EKE40562.1 - 0.0097 16.2 0.0 0.0097 16.2 0.0 4.8 3 1 1 4 4 2 1 AAA domain MMR_HSR1 PF01926.18 EKE40562.1 - 0.015 15.2 0.1 0.065 13.1 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EKE40562.1 - 0.015 15.2 2.1 0.016 15.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.17 EKE40562.1 - 0.018 14.4 0.1 0.056 12.8 0.1 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EKE40562.1 - 0.022 13.6 0.0 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 EKE40562.1 - 0.022 14.3 2.6 0.03 13.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EKE40562.1 - 0.033 13.9 0.2 0.033 13.9 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EKE40562.1 - 0.044 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EKE40562.1 - 0.22 11.8 0.0 0.22 11.8 0.0 4.8 4 1 0 4 4 2 0 AAA domain AAA_21 PF13304.1 EKE40562.1 - 0.89 9.4 0.0 0.89 9.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain Kinesin PF00225.18 EKE40564.1 - 1.1e-76 257.7 0.5 1.1e-76 257.7 0.3 1.7 2 0 0 2 2 2 1 Kinesin motor domain HALZ PF02183.13 EKE40564.1 - 0.0071 16.0 3.2 0.0071 16.0 2.2 3.1 3 0 0 3 3 3 1 Homeobox associated leucine zipper DUF87 PF01935.12 EKE40564.1 - 0.028 14.2 7.7 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF1875 PF08961.5 EKE40564.1 - 3.2 6.9 14.6 1.1 8.5 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) bZIP_1 PF00170.16 EKE40564.1 - 5.4 7.0 17.4 0.11 12.4 2.5 3.1 2 1 1 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.10 EKE40564.1 - 7.4 6.4 17.7 0.096 12.5 2.0 2.7 2 0 0 2 2 2 0 Basic region leucine zipper TMF_TATA_bd PF12325.3 EKE40564.1 - 7.4 6.3 22.5 5 6.8 7.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding fn1 PF00039.13 EKE40565.1 - 0.11 12.3 0.1 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Fibronectin type I domain WTF PF03303.8 EKE40567.1 - 0.001 18.5 2.4 0.0016 17.8 1.7 1.3 1 1 0 1 1 1 1 WTF protein ABC2_membrane_3 PF12698.2 EKE40567.1 - 0.0084 15.1 3.9 0.01 14.9 2.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein PEN-2 PF10251.4 EKE40567.1 - 0.28 11.4 4.1 0.5 10.6 2.9 1.5 1 1 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Herpes_UL45 PF05473.7 EKE40567.1 - 2.6 7.4 5.9 13 5.1 4.1 1.9 1 1 0 1 1 1 0 UL45 protein Baculo_E56 PF04639.7 EKE40567.1 - 5.5 5.5 5.3 4.1 5.9 0.1 1.9 1 1 1 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope IGF2_C PF08365.6 EKE40568.1 - 0.032 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide bZIP_Maf PF03131.12 EKE40570.1 - 0.00056 20.1 7.4 0.00072 19.7 5.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF16 PF01519.11 EKE40570.1 - 0.0011 19.1 8.5 0.0016 18.6 5.9 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 bZIP_2 PF07716.10 EKE40570.1 - 0.022 14.5 6.9 0.022 14.5 4.8 2.2 2 2 0 2 2 2 0 Basic region leucine zipper BRICHOS PF04089.9 EKE40570.1 - 0.087 12.6 0.8 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 BRICHOS domain AAA_23 PF13476.1 EKE40570.1 - 0.35 11.1 12.8 0.39 11.0 8.9 1.1 1 0 0 1 1 1 0 AAA domain Laminin_I PF06008.9 EKE40570.1 - 0.84 8.8 10.3 2.2 7.5 0.4 2.0 1 1 1 2 2 2 0 Laminin Domain I DUF1664 PF07889.7 EKE40570.1 - 1.2 8.9 7.8 2.5 7.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PRP1_N PF06424.7 EKE40570.1 - 4.2 7.6 6.5 9.2 6.5 4.6 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DNA_mis_repair PF01119.14 EKE40571.1 - 1.9e-20 72.4 1.3 5e-20 71.1 0.9 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EKE40571.1 - 1.8e-09 37.3 0.0 1.8e-09 37.3 0.0 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKE40571.1 - 4.7e-09 35.9 0.2 1.1e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0066 PF01980.11 EKE40572.1 - 1.8e-34 118.2 0.1 7e-34 116.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family UPF0066 Mon1 PF03164.9 EKE40572.1 - 0.034 12.7 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 Orbi_NS3 PF01616.11 EKE40572.1 - 0.05 12.5 0.2 0.075 11.9 0.2 1.2 1 0 0 1 1 1 0 Orbivirus NS3 HSP20 PF00011.16 EKE40573.1 - 6.5e-15 54.8 0.0 9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HET PF06985.6 EKE40574.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.3 3 0 0 3 3 3 0 Heterokaryon incompatibility protein (HET) zf-CCCH PF00642.19 EKE40575.1 - 4.9e-18 64.3 15.2 1.1e-09 37.6 1.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 EKE40575.1 - 0.098 12.2 1.2 12 5.5 0.1 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster zf-CCCH_2 PF14608.1 EKE40575.1 - 0.16 11.9 16.5 1 9.4 2.4 3.1 2 2 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 EKE40576.1 - 2.5e-58 197.2 0.0 5.8e-58 196.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40576.1 - 3.7e-32 111.4 0.0 6.3e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE40576.1 - 1.4e-05 24.9 0.0 0.047 13.4 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family PH PF00169.24 EKE40576.1 - 0.00056 20.0 1.1 0.0014 18.8 0.0 2.3 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 EKE40576.1 - 0.00087 18.3 0.0 0.0019 17.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EKE40576.1 - 0.012 15.8 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain TMP_2 PF06791.8 EKE40576.1 - 0.18 11.4 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Cyclin_N PF00134.18 EKE40578.1 - 0.011 15.2 0.1 0.027 14.0 0.1 1.8 1 1 0 1 1 1 0 Cyclin, N-terminal domain HSF_DNA-bind PF00447.12 EKE40579.1 - 4.1e-19 68.6 3.6 1.3e-18 67.0 2.5 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding COG5 PF10392.4 EKE40579.1 - 0.012 15.6 0.7 0.012 15.6 0.5 2.9 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DUF3385 PF11865.3 EKE40579.1 - 1.3 8.9 6.5 2.5 8.0 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) DUF948 PF06103.6 EKE40579.1 - 2.7 7.9 8.5 0.089 12.6 0.9 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-BED PF02892.10 EKE40580.1 - 0.0014 18.3 2.3 0.0033 17.1 1.6 1.7 1 0 0 1 1 1 1 BED zinc finger Ras PF00071.17 EKE40581.1 - 1.4e-25 89.5 1.8 1.7e-25 89.3 1.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40581.1 - 2.6e-10 40.8 0.2 4.7e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40581.1 - 9.8e-08 31.4 1.4 1.2e-07 31.1 1.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Septin PF00735.13 EKE40581.1 - 0.0041 16.1 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 EKE40581.1 - 0.02 14.4 0.8 5.4 6.4 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EKE40581.1 - 0.026 14.6 0.1 0.07 13.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EKE40581.1 - 0.031 13.1 0.4 0.072 11.9 0.1 1.6 1 1 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 EKE40581.1 - 0.054 12.6 0.1 2.1 7.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EKE40581.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 EKE40581.1 - 0.085 13.6 0.0 0.23 12.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 EKE40581.1 - 0.097 12.3 0.3 0.15 11.7 0.2 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ureidogly_hydro PF04115.7 EKE40581.1 - 0.14 11.5 0.0 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Ureidoglycolate hydrolase Nse4-Nse3_bdg PF15412.1 EKE40581.1 - 0.14 12.0 0.2 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE SRP54 PF00448.17 EKE40581.1 - 0.22 10.9 2.9 2.9 7.2 0.2 2.6 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain F-box PF00646.28 EKE40582.1 - 0.00031 20.3 0.0 0.00092 18.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKE40582.1 - 0.025 14.2 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like LIM PF00412.17 EKE40583.1 - 4.3e-11 42.7 4.8 6.4e-11 42.1 3.3 1.3 1 0 0 1 1 1 1 LIM domain YhfH PF14149.1 EKE40583.1 - 3.5 7.5 7.6 3.5 7.4 0.2 2.8 2 1 0 2 2 2 0 YhfH-like protein Tic20 PF09685.5 EKE40584.1 - 4.9e-10 39.3 14.2 5.7e-10 39.1 9.9 1.0 1 0 0 1 1 1 1 Tic20-like protein DUF2516 PF10724.4 EKE40584.1 - 0.059 13.3 6.0 0.093 12.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) CcoS PF03597.10 EKE40584.1 - 0.23 10.9 0.2 0.23 10.9 0.1 3.0 2 1 1 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type Herpes_LMP2 PF07415.6 EKE40584.1 - 1.2 7.7 8.1 1.4 7.4 5.6 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Serinc PF03348.10 EKE40584.1 - 4.4 5.9 13.2 5.4 5.6 9.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) F-box-like PF12937.2 EKE40585.1 - 0.0009 18.9 0.4 0.016 14.8 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKE40585.1 - 0.0022 17.5 0.1 0.035 13.7 0.0 2.5 2 0 0 2 2 2 1 F-box domain Gtr1_RagA PF04670.7 EKE40585.1 - 0.013 14.6 0.2 0.092 11.8 0.0 2.0 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region DEAD PF00270.24 EKE40586.1 - 7.6e-44 149.1 0.0 6.8e-43 146.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE40586.1 - 1.6e-25 88.7 0.1 7.1e-25 86.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE40586.1 - 4.2e-05 23.4 0.0 9.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IF-2B PF01008.12 EKE40587.1 - 5.4e-50 169.9 0.5 3e-49 167.4 0.4 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family Met_gamma_lyase PF06838.6 EKE40587.1 - 0.038 12.2 0.0 0.051 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Lysozyme_like PF13702.1 EKE40587.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Lysozyme-like OST3_OST6 PF04756.8 EKE40588.1 - 3.7e-15 55.8 4.1 4.2e-15 55.6 2.8 1.0 1 0 0 1 1 1 1 OST3 / OST6 family PepSY_TM PF03929.11 EKE40588.1 - 0.55 10.7 3.0 1.7 9.1 0.1 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix Pkinase_Tyr PF07714.12 EKE40590.1 - 3.9e-19 68.7 0.0 8.1e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40590.1 - 1.1e-17 64.0 0.0 2.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ras PF00071.17 EKE40591.1 - 6.1e-14 51.7 0.1 7.2e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40591.1 - 0.016 15.6 0.1 0.033 14.6 0.0 1.6 2 0 0 2 2 2 0 Miro-like protein DDE_Tnp_ISL3 PF01610.12 EKE40591.1 - 0.051 13.1 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Transposase Thioredoxin PF00085.15 EKE40593.1 - 2.9e-28 97.6 0.0 3.7e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE40593.1 - 2.3e-06 27.7 0.2 3.8e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKE40593.1 - 3.9e-05 23.6 0.0 7.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EKE40593.1 - 0.00032 20.2 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EKE40593.1 - 0.00068 18.4 0.0 0.00072 18.3 0.0 1.0 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.16 EKE40593.1 - 0.0035 17.0 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EKE40593.1 - 0.0075 16.2 0.1 0.0091 15.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EKE40593.1 - 0.018 14.5 0.1 0.021 14.3 0.1 1.3 1 1 0 1 1 1 0 Redoxin EMP24_GP25L PF01105.19 EKE40594.1 - 6.9e-33 113.9 3.0 8.7e-33 113.5 2.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.17 EKE40595.1 - 1.7e-53 180.2 0.2 2e-53 180.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40595.1 - 6.2e-21 75.1 0.0 1e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40595.1 - 6.6e-18 64.5 0.1 8.1e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE40595.1 - 1.6e-08 33.9 0.1 1.9e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE40595.1 - 1.3e-05 24.7 0.4 5.7e-05 22.6 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE40595.1 - 0.00021 21.2 0.2 0.00036 20.4 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EKE40595.1 - 0.00031 20.2 0.4 0.0048 16.3 0.3 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EKE40595.1 - 0.00085 19.4 0.0 0.0019 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EKE40595.1 - 0.0023 17.1 0.0 0.0042 16.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EKE40595.1 - 0.0024 17.6 0.3 0.0033 17.1 0.2 1.1 1 0 0 1 1 1 1 Archaeal ATPase FeoB_N PF02421.13 EKE40595.1 - 0.0027 17.0 1.8 0.026 13.8 1.2 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 EKE40595.1 - 0.0084 15.1 0.3 0.028 13.4 0.0 1.9 2 0 0 2 2 2 1 Septin ATP-synt_ab PF00006.20 EKE40595.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EKE40595.1 - 0.018 14.4 0.0 0.2 11.0 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EKE40595.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.18 EKE40595.1 - 0.029 13.1 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family MobB PF03205.9 EKE40595.1 - 0.033 13.8 0.1 0.059 13.0 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EKE40595.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKE40595.1 - 0.048 14.4 0.1 0.11 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKE40595.1 - 0.057 13.1 0.0 0.079 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EKE40595.1 - 0.097 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EKE40595.1 - 0.098 11.8 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 HA2 PF04408.18 EKE40596.1 - 3.3e-25 88.0 0.0 6.7e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EKE40596.1 - 9.3e-21 73.7 0.0 1.9e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EKE40596.1 - 3.1e-12 46.1 0.2 6.7e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE40596.1 - 8.5e-09 35.1 0.6 7.4e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE40596.1 - 9.8e-05 22.5 0.0 0.00028 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EKE40596.1 - 0.00082 19.2 0.0 0.84 9.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EKE40596.1 - 0.0038 17.1 0.9 0.066 13.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKE40596.1 - 0.0044 16.7 0.5 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EKE40596.1 - 0.008 15.1 0.1 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EKE40596.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain UPF0079 PF02367.12 EKE40596.1 - 0.015 14.8 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EKE40596.1 - 0.044 13.2 0.0 0.17 11.3 0.0 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1620 PF07774.8 EKE40598.1 - 3.4e-20 72.2 5.3 3.4e-20 72.2 3.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) RasGAP PF00616.14 EKE40599.1 - 1.5e-05 24.7 10.4 0.0011 18.6 7.2 3.2 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase TPR_MLP1_2 PF07926.7 EKE40599.1 - 0.4 10.4 9.6 0.74 9.5 6.6 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Esterase PF00756.15 EKE40601.1 - 3.3e-21 75.8 0.0 9.2e-21 74.4 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EKE40601.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EKE40601.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.4 EKE40601.1 - 0.14 11.3 0.0 0.37 10.0 0.0 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Man-6-P_recep PF02157.10 EKE40604.1 - 6.1e-08 32.0 0.1 9e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EKE40604.1 - 0.0022 17.2 8.3 0.0035 16.6 3.8 2.4 1 1 1 2 2 2 1 Autophagy-related protein 27 Rep_fac-A_3 PF08661.6 EKE40604.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Replication factor A protein 3 PIG-P PF08510.7 EKE40604.1 - 2 8.0 5.3 0.95 9.1 1.9 1.7 2 0 0 2 2 2 0 PIG-P Polysacc_deac_1 PF01522.16 EKE40605.1 - 3.2e-24 84.9 0.0 4.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Hpr_kinase_N PF02603.11 EKE40605.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase N terminus DUF4215 PF13948.1 EKE40605.1 - 3 8.1 5.0 22 5.3 3.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4215) Dispanin PF04505.7 EKE40606.1 - 1.1 8.9 3.0 3.5 7.2 2.1 1.9 1 0 0 1 1 1 0 Interferon-induced transmembrane protein TLD PF07534.11 EKE40612.1 - 2.1e-05 24.5 3.3 4.5e-05 23.4 1.9 2.0 2 1 0 2 2 2 1 TLD DUF1104 PF06518.6 EKE40612.1 - 0.73 10.0 8.7 1.5 9.0 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) TLD PF07534.11 EKE40613.1 - 6.5e-05 22.9 0.1 0.00025 21.0 0.0 1.9 1 1 1 2 2 2 1 TLD DUF1810 PF08837.6 EKE40616.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) DUF972 PF06156.8 EKE40616.1 - 0.056 13.8 0.6 0.056 13.8 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) LETM1 PF07766.8 EKE40616.1 - 0.068 12.2 4.0 0.053 12.5 1.8 1.5 2 0 0 2 2 2 0 LETM1-like protein T2SK PF03934.8 EKE40616.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K DASH_Hsk3 PF08227.6 EKE40616.1 - 0.13 12.4 0.2 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like SDH_alpha PF03313.10 EKE40617.1 - 0.089 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain zf-C2HC5 PF06221.8 EKE40617.1 - 1.1 9.0 7.1 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Pneumo_phosprot PF02478.11 EKE40618.1 - 0.063 12.7 2.7 0.082 12.4 1.9 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DUF1754 PF08555.5 EKE40618.1 - 0.18 12.3 12.0 0.26 11.9 8.3 1.1 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FAM176 PF14851.1 EKE40618.1 - 0.42 10.2 5.6 0.52 9.9 3.9 1.2 1 0 0 1 1 1 0 FAM176 family Cellulose_synt PF03552.9 EKE40618.1 - 5.2 5.2 5.9 6.5 4.9 4.1 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3048 PF11258.3 EKE40618.1 - 5.7 5.9 6.9 7.6 5.5 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) CDC45 PF02724.9 EKE40618.1 - 7.6 4.4 7.3 9.1 4.1 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PH PF00169.24 EKE40619.1 - 6.9e-07 29.4 3.1 9.8e-07 28.9 0.7 2.4 2 1 0 2 2 2 1 PH domain PH_3 PF14593.1 EKE40619.1 - 0.0026 17.6 0.3 0.012 15.4 0.0 2.2 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EKE40619.1 - 0.0073 16.5 0.2 0.023 14.9 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain APC10 PF03256.11 EKE40620.1 - 1.2e-36 126.1 0.0 1.5e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EKE40620.1 - 0.00085 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain FAE1_CUT1_RppA PF08392.7 EKE40621.1 - 2.7e-95 318.7 0.0 4.5e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EKE40621.1 - 2.3e-11 43.5 0.0 5.3e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.10 EKE40621.1 - 5.3e-08 32.9 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EKE40621.1 - 5.6e-05 22.4 0.0 9.8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 EKE40621.1 - 0.0019 17.8 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF930 PF06059.7 EKE40621.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) Myb_DNA-bind_4 PF13837.1 EKE40622.1 - 0.00032 20.7 2.2 0.00032 20.7 1.5 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain OprF PF05736.6 EKE40622.1 - 0.02 14.4 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 OprF membrane domain ABC2_membrane_3 PF12698.2 EKE40622.1 - 0.081 11.9 3.1 0.093 11.7 2.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF573 PF04504.9 EKE40622.1 - 0.2 11.9 7.5 0.14 12.4 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Glyco_hydro_25 PF01183.15 EKE40623.1 - 5e-05 23.2 0.7 5.9e-05 22.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 MMR_HSR1 PF01926.18 EKE40624.1 - 8e-18 64.4 0.1 2.8e-17 62.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EKE40624.1 - 1.1e-15 57.1 0.0 2.7e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EKE40624.1 - 6.3e-09 35.3 0.0 2e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EKE40624.1 - 0.0034 17.8 0.1 0.023 15.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EKE40624.1 - 0.0037 17.1 0.1 0.2 11.4 0.0 2.3 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 EKE40624.1 - 0.014 14.1 0.2 0.083 11.6 0.0 2.2 2 1 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 EKE40624.1 - 0.016 14.6 1.0 5.4 6.3 0.1 3.9 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain NinE PF05322.6 EKE40624.1 - 0.022 14.4 0.4 0.054 13.2 0.3 1.6 1 0 0 1 1 1 0 NINE Protein B2-adapt-app_C PF09066.5 EKE40625.1 - 0.012 15.4 0.1 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain SET PF00856.23 EKE40626.1 - 2.8e-14 53.7 0.3 1.6e-13 51.3 0.1 2.3 2 1 0 2 2 2 1 SET domain Myb_DNA-binding PF00249.26 EKE40627.1 - 1.9e-25 88.6 0.3 1.9e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE40627.1 - 2.2e-25 88.4 0.6 1.8e-13 50.3 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Exo70 PF03081.10 EKE40627.1 - 0.13 11.0 0.1 2.1 7.0 0.0 2.0 1 1 1 2 2 2 0 Exo70 exocyst complex subunit PP2C PF00481.16 EKE40628.1 - 1.2e-27 96.9 0.2 1.5e-27 96.5 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE40628.1 - 1.4e-05 24.5 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PTH2 PF01981.11 EKE40629.1 - 7.8e-39 131.9 0.1 8.5e-39 131.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PRA1 PF03208.14 EKE40630.1 - 4.3e-06 26.1 4.9 5.1e-06 25.9 3.4 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF1212 PF06738.7 EKE40630.1 - 0.015 14.7 2.8 0.02 14.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) RseC_MucC PF04246.7 EKE40630.1 - 0.024 14.2 7.1 0.13 11.8 0.1 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Nbas_N PF15492.1 EKE40630.1 - 0.13 11.3 0.5 0.16 11.0 0.4 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal YwiC PF14256.1 EKE40630.1 - 0.83 9.7 6.1 2.3 8.2 4.1 1.7 1 1 0 1 1 1 0 YwiC-like protein DUF846 PF05832.7 EKE40630.1 - 1.3 8.7 7.8 0.81 9.3 0.4 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) Rab5ip PF07019.7 EKE40630.1 - 1.4 9.1 8.8 1.5 9.0 0.6 2.4 1 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) DUF2244 PF10003.4 EKE40630.1 - 5.7 6.3 7.7 0.16 11.3 0.2 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Drf_FH3 PF06367.11 EKE40631.1 - 0.0045 16.4 1.0 0.01 15.2 0.5 1.8 1 1 0 1 1 1 1 Diaphanous FH3 Domain PP2C PF00481.16 EKE40632.1 - 4.5e-30 104.8 0.1 6.2e-30 104.4 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE40632.1 - 0.0026 17.2 0.0 0.036 13.4 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosom_S12_S23 PF00164.20 EKE40632.1 - 0.057 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S12/S23 UEV PF05743.8 EKE40633.1 - 8.9e-11 41.5 1.5 1.7e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 UEV domain Vps23_core PF09454.5 EKE40633.1 - 0.027 14.0 0.0 0.069 12.7 0.0 1.7 1 0 0 1 1 1 0 Vps23 core domain Spc7_C2 PF15577.1 EKE40633.1 - 0.037 13.6 1.4 0.45 10.1 0.0 2.7 3 0 0 3 3 3 0 Spc7_C2 Aa_trans PF01490.13 EKE40634.1 - 4.1e-19 68.3 29.3 1.3e-18 66.7 20.3 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_topoisoIV PF00521.15 EKE40635.1 - 0.039 12.8 4.0 0.055 12.3 2.8 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF2638 PF10937.3 EKE40636.1 - 0.19 12.7 7.9 0.084 13.9 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) APG6 PF04111.7 EKE40637.1 - 0.072 12.1 1.8 0.14 11.1 0.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4522 PF15022.1 EKE40637.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) S_tail_recep_bd PF14928.1 EKE40638.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain Metallophos PF00149.23 EKE40639.1 - 2.7e-12 46.4 3.1 5.1e-12 45.5 2.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE40639.1 - 2.4e-06 27.4 0.8 4.6e-06 26.5 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S10 PF00338.17 EKE40640.1 - 0.011 15.5 0.1 0.054 13.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e CENP-T PF15511.1 EKE40642.1 - 2.8e-05 23.5 13.6 2.8e-05 23.5 9.4 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T TIG PF01833.19 EKE40644.1 - 1.1e-08 34.9 3.2 1.1e-06 28.4 0.2 2.5 2 0 0 2 2 2 2 IPT/TIG domain FYVE PF01363.16 EKE40644.1 - 8 6.4 14.7 33 4.4 10.2 2.1 1 1 0 1 1 1 0 FYVE zinc finger DUF2439 PF10382.4 EKE40646.1 - 1.4e-08 34.7 4.8 1.7e-07 31.3 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) Taxilin PF09728.4 EKE40647.1 - 0.058 12.4 0.5 7 5.6 0.1 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein B-block_TFIIIC PF04182.7 EKE40648.1 - 4.3e-13 48.8 1.3 3.8e-12 45.8 0.1 3.1 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR PF01047.17 EKE40648.1 - 1.6e-05 24.4 0.2 0.00072 19.2 0.0 3.2 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.2 EKE40648.1 - 0.0014 18.2 0.0 0.079 12.6 0.0 3.4 3 1 0 3 3 3 1 MarR family HTH_24 PF13412.1 EKE40648.1 - 0.0014 17.9 0.4 0.62 9.4 0.1 3.8 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 EKE40648.1 - 0.11 12.3 0.0 16 5.3 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain LRR_5 PF13306.1 EKE40649.1 - 5.4e-176 575.8 126.9 3.6e-30 104.3 7.0 9.4 5 3 4 9 9 9 9 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE40649.1 - 2.6e-69 228.8 31.4 3.1e-07 30.0 0.5 15.0 6 3 12 18 18 18 18 Leucine rich repeat Clathrin_bdg PF15045.1 EKE40649.1 - 0.014 14.8 0.1 2.6 7.6 0.0 3.3 3 0 0 3 3 3 0 Clathrin-binding box of Aftiphilin, vesicle trafficking DUF106 PF01956.11 EKE40650.1 - 1.8e-26 92.6 1.8 2.2e-26 92.3 1.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 EBA-175_VI PF11556.3 EKE40650.1 - 0.012 15.7 0.2 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 COX2_TM PF02790.10 EKE40650.1 - 0.023 14.6 3.9 0.074 13.0 0.1 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain FlxA PF14282.1 EKE40650.1 - 0.071 13.0 0.9 0.1 12.5 0.6 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF2208 PF09973.4 EKE40650.1 - 1.2 8.2 7.3 11 5.1 5.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) CVNH PF08881.5 EKE40651.1 - 0.0033 17.6 0.0 0.038 14.1 0.0 2.7 1 1 0 1 1 1 1 CVNH domain COG4 PF08318.7 EKE40652.1 - 7.1e-08 31.5 25.2 1.2e-05 24.2 4.0 3.0 2 1 1 3 3 3 2 COG4 transport protein RB_A PF01858.12 EKE40652.1 - 2.8 7.5 9.8 0.23 11.0 0.4 2.8 3 1 0 3 3 3 0 Retinoblastoma-associated protein A domain Syntaxin PF00804.20 EKE40652.1 - 8.2 6.6 14.4 0.075 13.2 2.1 3.3 3 2 0 3 3 3 0 Syntaxin CitMHS PF03600.11 EKE40653.1 - 1e-18 67.0 0.0 4.7e-18 64.8 0.0 2.0 1 1 1 2 2 2 1 Citrate transporter TrkA_C PF02080.16 EKE40653.1 - 9.7e-06 25.0 0.0 0.019 14.5 0.0 2.5 2 0 0 2 2 2 2 TrkA-C domain DUF2701 PF10857.3 EKE40653.1 - 9.5 6.0 13.2 4.7 7.0 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2701) RTC PF01137.16 EKE40654.1 - 1e-50 171.6 0.1 1.2e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RRM_1 PF00076.17 EKE40655.1 - 3.9e-18 64.8 0.3 3.1e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40655.1 - 3.3e-14 52.4 1.0 1.4e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40655.1 - 4e-09 36.3 0.1 3e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE40655.1 - 0.0016 18.1 0.2 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EKE40655.1 - 0.018 14.6 0.3 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 Calcipressin Limkain-b1 PF11608.3 EKE40655.1 - 0.13 12.0 0.3 0.3 10.8 0.2 1.6 1 0 0 1 1 1 0 Limkain b1 Ras PF00071.17 EKE40656.1 - 1.1e-46 158.1 0.5 1.4e-46 157.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40656.1 - 1.8e-18 67.1 0.1 2.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40656.1 - 7.1e-15 54.6 0.5 9.6e-15 54.2 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKE40656.1 - 8.4e-11 41.4 0.1 1.3e-10 40.7 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE40656.1 - 3.8e-07 29.4 0.3 4.5e-07 29.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE40656.1 - 3.1e-05 23.8 0.1 5.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE40656.1 - 0.00093 18.6 0.5 0.05 13.0 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKE40656.1 - 0.0041 16.6 0.4 0.016 14.7 0.3 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EKE40656.1 - 0.015 15.4 0.0 0.29 11.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EKE40656.1 - 0.019 14.9 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EKE40656.1 - 0.048 12.3 0.6 0.14 10.7 0.2 1.8 1 1 1 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 EKE40656.1 - 0.053 12.6 0.1 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EKE40656.1 - 0.072 12.9 0.0 0.38 10.5 0.0 1.9 1 1 0 2 2 2 0 Dynamin family TK PF00265.13 EKE40657.1 - 4.6e-63 211.9 0.1 5.5e-63 211.6 0.1 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 EKE40657.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE40657.1 - 0.0023 17.6 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase Herpes_ori_bp PF02399.10 EKE40657.1 - 0.022 12.7 0.0 0.031 12.2 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein DUF676 PF05057.9 EKE40658.1 - 1.1e-20 73.8 0.0 2.8e-20 72.5 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EKE40658.1 - 0.00023 20.7 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EKE40658.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EKE40658.1 - 0.19 11.5 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.17 EKE40659.1 - 3.4e-41 140.3 0.2 4.2e-41 140.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40659.1 - 9.5e-21 74.4 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40659.1 - 2.1e-11 43.3 0.1 2.6e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE40659.1 - 4.6e-05 22.9 0.3 0.00035 20.0 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE40659.1 - 4.9e-05 22.5 0.0 6.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE40659.1 - 0.00036 20.4 0.0 0.00058 19.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EKE40659.1 - 0.027 13.4 0.1 4 6.3 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_22 PF13401.1 EKE40659.1 - 0.029 14.5 0.2 0.07 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EKE40659.1 - 0.031 13.4 0.0 0.047 12.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF445 PF04286.7 EKE40659.1 - 0.041 13.4 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_11 PF13086.1 EKE40659.1 - 0.045 13.3 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EKE40659.1 - 0.075 12.7 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3627 PF12299.3 EKE40659.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) DEAD PF00270.24 EKE40660.1 - 3e-40 137.4 0.2 3e-40 137.4 0.2 2.9 3 1 1 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE40660.1 - 2.7e-22 78.4 0.0 8.3e-22 76.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKE40660.1 - 0.003 16.3 0.0 0.0094 14.7 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain PEX11 PF05648.9 EKE40660.1 - 0.051 12.8 4.9 0.88 8.7 0.9 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DSPc PF00782.15 EKE40661.1 - 2.7e-20 72.3 3.8 3.3e-20 72.0 0.2 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EKE40661.1 - 0.00052 18.8 0.1 0.00074 18.3 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DUF1947 PF09183.5 EKE40661.1 - 8.4 6.2 8.5 6.5 6.5 2.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) LCAT PF02450.10 EKE40662.1 - 3.1e-40 138.3 1.7 6.9e-38 130.6 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EKE40662.1 - 9.1e-07 28.6 0.0 5.8e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 EKE40662.1 - 5.4e-06 25.8 0.1 1.5e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EKE40662.1 - 2.3e-05 24.3 0.0 0.021 14.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EKE40662.1 - 0.0053 16.3 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EKE40662.1 - 0.0062 16.3 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tubulin PF00091.20 EKE40662.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain DUF1177 PF06675.6 EKE40662.1 - 0.019 13.5 0.0 0.032 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) DUF570 PF04489.8 EKE40662.1 - 0.022 13.1 0.2 0.033 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Lipase_2 PF01674.13 EKE40662.1 - 0.05 12.9 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 2) Cyto_ox_2 PF02322.10 EKE40662.1 - 0.13 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II TBP PF00352.16 EKE40663.1 - 2.6e-63 209.3 1.0 9.6e-32 108.2 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EKE40663.1 - 0.00027 20.9 0.1 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) Peptidase_C71 PF12386.3 EKE40663.1 - 0.045 13.1 0.1 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Prenyltrans PF00432.16 EKE40664.1 - 1.2e-14 53.5 3.9 0.00068 19.1 0.0 5.9 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKE40664.1 - 2.3e-09 37.6 0.0 0.00017 21.9 0.0 3.1 1 1 1 2 2 2 2 Prenyltransferase-like NUDIX_2 PF13869.1 EKE40665.1 - 9.9e-65 217.3 3.0 9.9e-65 217.3 2.1 1.4 2 0 0 2 2 2 1 Nucleotide hydrolase GIDA_assoc_3 PF13932.1 EKE40665.1 - 0.072 13.1 0.6 0.072 13.1 0.4 2.2 2 1 1 3 3 3 0 GidA associated domain 3 Mt_ATP-synt_B PF05405.9 EKE40666.1 - 0.0034 16.8 2.3 0.013 14.9 0.6 2.4 3 0 0 3 3 3 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Terminase_4 PF05119.7 EKE40666.1 - 0.0097 16.0 0.6 0.18 11.9 0.0 2.8 3 0 0 3 3 3 1 Phage terminase, small subunit Hat1_N PF10394.4 EKE40668.1 - 7e-18 65.2 5.3 7e-18 65.2 3.7 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Glyco_hydro_12 PF01670.11 EKE40668.1 - 0.00044 20.0 0.5 0.053 13.3 0.0 2.9 2 1 1 3 3 3 1 Glycosyl hydrolase family 12 Acetyltransf_7 PF13508.1 EKE40668.1 - 0.0023 18.0 0.2 0.016 15.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mannosyl_trans3 PF11051.3 EKE40668.1 - 0.0026 17.1 0.1 0.0056 16.0 0.1 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Acetyltransf_1 PF00583.19 EKE40668.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family LRR_4 PF12799.2 EKE40669.1 - 5.7e-16 57.7 29.7 1.3e-06 27.8 2.0 6.0 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE40669.1 - 1.8e-15 56.4 17.7 3.9e-08 32.9 0.4 5.3 3 2 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 EKE40669.1 - 6.5e-08 31.5 29.8 0.59 10.3 0.2 9.4 10 1 0 10 10 10 4 Leucine Rich Repeat LRRNT_2 PF08263.7 EKE40669.1 - 2.6e-06 27.2 0.2 5.4e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF1699 PF08004.6 EKE40669.1 - 2.5e-05 23.8 0.0 6.7e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1699) LRR_6 PF13516.1 EKE40669.1 - 0.0015 18.3 24.5 1.1 9.5 0.2 7.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EKE40669.1 - 0.013 15.5 11.4 5.6 7.6 0.0 6.8 7 0 0 7 7 7 0 Leucine rich repeat zf-DHHC PF01529.15 EKE40670.1 - 3.3e-32 111.2 11.9 3.3e-32 111.2 8.3 2.5 2 2 0 2 2 2 1 DHHC palmitoyltransferase LKAAEAR PF15478.1 EKE40670.1 - 0.34 11.1 3.2 0.49 10.6 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif Ribosomal_S8 PF00410.14 EKE40671.1 - 1.7e-11 44.0 0.1 1.9e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 FlgI PF02119.11 EKE40671.1 - 0.044 12.4 0.3 0.047 12.3 0.2 1.0 1 0 0 1 1 1 0 Flagellar P-ring protein UNC-93 PF05978.11 EKE40672.1 - 3.3e-17 62.4 6.5 3.3e-17 62.4 4.5 4.5 4 1 1 5 5 5 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EKE40672.1 - 0.00045 19.0 45.7 0.00088 18.0 12.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Vps53_N PF04100.7 EKE40673.1 - 1.6e-31 109.4 9.1 4.1e-31 108.1 6.3 1.6 1 0 0 1 1 1 1 Vps53-like, N-terminal CRISPR_Cas2 PF09827.4 EKE40673.1 - 0.1 12.7 1.6 0.55 10.4 0.1 2.8 2 0 0 2 2 2 0 CRISPR associated protein Cas2 UPF0179 PF03684.8 EKE40675.1 - 0.0066 16.0 0.1 0.0066 16.0 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0179) DUF2294 PF10057.4 EKE40675.1 - 0.035 13.7 0.2 0.074 12.7 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) ZapA PF05164.8 EKE40675.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapA ATP-synt_F PF01990.12 EKE40675.1 - 0.15 12.5 1.9 0.26 11.6 1.2 1.5 1 1 0 1 1 1 0 ATP synthase (F/14-kDa) subunit tRNA-synt_2c PF01411.14 EKE40678.1 - 1.7e-57 195.0 0.1 7e-29 100.5 0.0 3.5 3 1 1 4 4 4 3 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EKE40678.1 - 2.3e-12 46.5 2.6 2.3e-12 46.5 1.8 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain CTP_transf_2 PF01467.21 EKE40679.1 - 5.1e-09 36.3 0.4 8.1e-09 35.7 0.2 1.5 1 1 0 1 1 1 1 Cytidylyltransferase Pkinase PF00069.20 EKE40680.1 - 8.1e-22 77.6 0.1 1.3e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EKE40680.1 - 4.1e-07 29.2 0.1 6.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 EKE40680.1 - 0.00021 20.4 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EKE40680.1 - 0.002 17.4 0.3 0.0057 16.0 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EKE40680.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKE40680.1 - 0.0079 15.7 0.1 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase PIP49_C PF12260.3 EKE40680.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Kdo PF06293.9 EKE40680.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_Tnp_Tc3_2 PF01498.13 EKE40682.1 - 0.031 14.3 1.8 0.051 13.6 0.4 2.0 2 0 0 2 2 2 0 Transposase CYTL1 PF15153.1 EKE40682.1 - 0.18 11.5 6.0 0.53 9.9 0.0 3.2 3 1 1 4 4 4 0 Cytokine-like protein 1 Prenyltrans_2 PF13249.1 EKE40683.1 - 0.0026 18.1 0.0 0.37 11.2 0.0 2.4 1 1 1 2 2 2 1 Prenyltransferase-like PhaG_MnhG_YufB PF03334.9 EKE40683.1 - 0.024 14.6 0.4 0.024 14.6 0.3 3.3 4 0 0 4 4 4 0 Na+/H+ antiporter subunit DUF3353 PF11833.3 EKE40683.1 - 0.71 9.2 3.5 0.69 9.3 0.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) LRR_5 PF13306.1 EKE40684.1 - 3.3e-07 30.0 16.9 0.014 15.1 0.5 5.1 3 1 2 5 5 5 3 Leucine rich repeats (6 copies) FNIP PF05725.7 EKE40684.1 - 0.084 12.8 20.4 3.4 7.7 0.0 7.1 7 1 0 7 7 7 0 FNIP Repeat Pkinase_Tyr PF07714.12 EKE40685.1 - 6.9e-56 189.1 0.0 1.1e-55 188.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40685.1 - 1.2e-40 139.3 0.0 2.9e-40 138.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kelch_6 PF13964.1 EKE40685.1 - 8.3e-20 70.0 13.0 0.00019 21.4 0.1 6.5 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 EKE40685.1 - 2e-18 65.6 19.5 9.3e-05 21.9 1.3 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 EKE40685.1 - 2.1e-17 62.5 7.3 0.003 17.2 0.1 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EKE40685.1 - 1e-14 53.6 7.0 0.0037 16.9 0.7 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 EKE40685.1 - 8e-14 51.2 15.7 0.003 17.4 0.1 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EKE40685.1 - 5.8e-13 48.6 1.7 4.7e-05 23.4 0.0 5.4 7 0 0 7 7 7 3 Galactose oxidase, central domain Pkinase_Tyr PF07714.12 EKE40686.1 - 5.3e-67 225.6 0.0 1.9e-60 204.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EKE40686.1 - 4e-45 153.9 0.0 6.4e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kelch_1 PF01344.20 EKE40686.1 - 1e-22 79.3 10.4 1.9e-06 27.3 0.8 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 EKE40686.1 - 2.9e-17 62.1 3.0 1.3e-05 24.8 0.0 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EKE40686.1 - 1.5e-16 59.7 7.9 0.00051 20.1 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 EKE40686.1 - 1.6e-15 56.7 0.1 0.0028 17.7 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EKE40686.1 - 1e-12 47.6 5.9 8.9e-05 22.3 0.2 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EKE40686.1 - 0.0066 16.1 8.4 13 5.7 0.0 5.6 6 0 0 6 6 6 2 Kelch motif DUF3647 PF12363.3 EKE40686.1 - 0.15 12.1 1.9 17 5.5 0.4 2.9 2 0 0 2 2 2 0 Phage protein Dus PF01207.12 EKE40687.1 - 5.7e-45 153.4 0.0 1.1e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EKE40687.1 - 0.0023 17.5 14.0 0.0027 17.3 0.2 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DHO_dh PF01180.16 EKE40687.1 - 0.041 12.8 0.1 0.25 10.2 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NanE PF04131.9 EKE40687.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 EKE40687.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI G-alpha PF00503.15 EKE40688.1 - 1.5e-98 330.0 0.0 2.2e-98 329.5 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EKE40688.1 - 5.4e-14 51.8 0.6 3.3e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE40688.1 - 0.00023 20.3 1.3 0.022 13.8 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE40688.1 - 0.0038 16.6 0.6 0.23 10.8 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EKE40688.1 - 0.0079 16.6 0.2 6.5 7.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EKE40688.1 - 0.017 15.0 0.1 0.44 10.5 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EKE40688.1 - 0.049 13.1 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PC_rep PF01851.17 EKE40690.1 - 4.3e-25 86.4 28.8 1.8e-06 27.8 0.0 10.7 11 0 0 11 11 11 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EKE40690.1 - 7.1e-18 64.6 0.7 4.6e-10 39.6 0.1 3.3 3 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EKE40690.1 - 2.4e-07 31.0 0.0 0.0015 18.9 0.0 3.6 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EKE40690.1 - 5.6e-06 25.9 0.0 0.7 10.1 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat DNA_alkylation PF08713.6 EKE40690.1 - 0.0011 18.4 0.0 0.0094 15.4 0.0 2.2 2 0 0 2 2 2 1 DNA alkylation repair enzyme SAC3_GANP PF03399.11 EKE40691.1 - 4.9e-36 124.2 2.5 7.7e-36 123.5 1.7 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family OmpH PF03938.9 EKE40691.1 - 0.15 11.9 3.1 0.38 10.6 2.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_S9 PF00326.16 EKE40692.1 - 5.4e-53 179.3 2.6 7.1e-53 178.9 0.4 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKE40692.1 - 5.3e-09 35.9 0.0 9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EKE40692.1 - 0.0005 19.5 1.9 0.015 14.7 0.5 2.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EKE40692.1 - 0.0045 16.4 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Putative esterase Chlorophyllase2 PF12740.2 EKE40692.1 - 0.008 15.0 0.1 0.15 10.9 0.0 2.7 3 0 0 3 3 3 1 Chlorophyllase enzyme PD40 PF07676.7 EKE40692.1 - 0.045 13.4 0.2 0.72 9.5 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ArfGap PF01412.13 EKE40693.1 - 1.3e-30 105.5 1.1 2.2e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf EnY2 PF10163.4 EKE40693.1 - 0.11 12.4 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor e(y)2 PAT1 PF09770.4 EKE40693.1 - 8.1 4.5 58.0 11 4.1 40.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Arm PF00514.18 EKE40694.1 - 0.016 15.0 0.0 2.3 8.1 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat FAM101 PF15068.1 EKE40695.1 - 0.0047 16.4 1.0 0.006 16.0 0.7 1.1 1 0 0 1 1 1 1 FAM101 family Cpn60_TCP1 PF00118.19 EKE40697.1 - 2.3e-144 481.6 10.9 2.7e-144 481.4 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family VanW PF04294.8 EKE40697.1 - 0.037 13.2 0.5 0.32 10.2 0.1 2.6 3 0 0 3 3 3 0 VanW like protein WD40 PF00400.27 EKE40698.1 - 2.8e-45 150.6 11.3 4.3e-09 35.9 0.1 10.6 11 1 0 11 11 11 8 WD domain, G-beta repeat Utp12 PF04003.7 EKE40698.1 - 2.7e-09 36.9 1.1 5.6e-09 35.8 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EKE40698.1 - 0.00029 19.1 0.1 0.67 8.0 0.0 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EKE40698.1 - 0.0079 15.9 0.1 0.3 10.7 0.0 3.4 4 1 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Ras PF00071.17 EKE40700.1 - 3.1e-57 192.4 0.0 3.8e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40700.1 - 2.4e-17 63.5 0.0 3.8e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40700.1 - 2.3e-12 46.4 0.0 2.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE40700.1 - 1e-05 25.0 0.0 0.00018 21.0 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE40700.1 - 0.0006 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE40700.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ldh_1_N PF00056.18 EKE40701.1 - 1.8e-34 118.5 0.2 2.5e-34 118.0 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EKE40701.1 - 6.4e-27 94.3 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain LRR_6 PF13516.1 EKE40702.1 - 3.5e-06 26.5 14.4 0.013 15.5 0.0 7.8 9 0 0 9 9 9 3 Leucine Rich repeat RasGAP PF00616.14 EKE40702.1 - 8.8e-05 22.2 10.7 9.1e-05 22.1 5.9 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase LRR_8 PF13855.1 EKE40702.1 - 0.035 13.8 8.3 1.8 8.3 0.0 5.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EKE40702.1 - 0.13 11.9 0.0 0.13 11.9 0.0 5.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) MRG PF05712.8 EKE40703.1 - 3e-20 71.9 3.6 1e-19 70.2 2.5 1.7 1 1 0 1 1 1 1 MRG zf-H2C2_2 PF13465.1 EKE40703.1 - 0.19 12.0 0.6 0.19 12.0 0.4 2.8 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EKE40703.1 - 4.2 7.9 10.2 0.55 10.6 1.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1151 PF06625.6 EKE40704.1 - 0.011 15.4 0.2 0.013 15.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) L31 PF09784.4 EKE40704.1 - 1.6 8.8 5.5 27 4.8 2.8 2.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 U1snRNP70_N PF12220.3 EKE40705.1 - 7.7e-09 35.7 0.1 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TPR_16 PF13432.1 EKE40706.1 - 1.2e-06 29.0 0.0 0.098 13.3 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKE40706.1 - 1.3e-06 28.6 4.0 0.0026 18.0 0.2 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EKE40706.1 - 6.7e-05 22.9 1.0 0.00058 19.9 0.2 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EKE40706.1 - 0.0002 21.7 0.5 1.2 9.9 0.2 4.0 2 1 3 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKE40706.1 - 0.00098 18.8 0.9 1.7 8.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EKE40706.1 - 0.0021 18.0 0.9 0.95 9.3 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF3366 PF11846.3 EKE40706.1 - 0.0035 17.2 0.1 0.024 14.5 0.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF3366) TPR_15 PF13429.1 EKE40706.1 - 0.004 16.2 0.3 0.87 8.5 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKE40706.1 - 0.0052 16.3 0.5 0.7 9.5 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_20 PF14561.1 EKE40706.1 - 0.0068 16.4 0.3 4.1 7.5 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Clathrin PF00637.15 EKE40706.1 - 0.018 14.6 1.9 0.024 14.2 1.0 1.6 1 1 0 1 1 1 0 Region in Clathrin and VPS ChAPs PF09295.5 EKE40706.1 - 0.024 13.4 0.8 0.027 13.2 0.6 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 EKE40706.1 - 0.051 13.5 2.5 0.75 9.7 0.1 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat UreF PF01730.11 EKE40706.1 - 0.067 13.3 0.1 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 UreF TPR_6 PF13174.1 EKE40706.1 - 0.074 13.5 4.9 9.3 6.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKE40706.1 - 0.39 10.6 6.2 2.5 8.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EKE40706.1 - 1.7 8.5 4.3 4.3 7.3 0.2 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Swi5 PF07061.6 EKE40706.1 - 3.5 7.4 5.8 2 8.2 0.8 2.7 3 1 0 3 3 3 0 Swi5 zf-RING_2 PF13639.1 EKE40707.1 - 2.7e-09 36.7 13.9 2.7e-09 36.7 9.6 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKE40707.1 - 6e-08 32.2 13.6 6e-08 32.2 9.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE40707.1 - 8.8e-07 28.8 16.4 8.8e-07 28.8 11.4 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE40707.1 - 4.8e-06 26.1 17.3 4.8e-06 26.1 12.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE40707.1 - 3e-05 23.6 16.5 3e-05 23.6 11.4 3.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EKE40707.1 - 0.01 15.8 12.5 0.01 15.8 8.6 3.3 2 2 0 2 2 2 0 RING-H2 zinc finger Metallophos PF00149.23 EKE40708.1 - 2.5e-29 102.1 0.6 3.8e-29 101.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EKE40708.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region LRR_4 PF12799.2 EKE40709.1 - 8.5e-13 47.6 23.5 6.2e-07 28.8 0.1 6.2 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE40709.1 - 2.7e-12 46.2 18.0 7.4e-07 28.8 0.0 5.0 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EKE40709.1 - 2.2e-08 32.9 10.4 0.82 9.9 0.0 7.7 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 EKE40709.1 - 3.5e-05 23.4 13.0 0.32 11.1 0.0 6.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 EKE40709.1 - 0.0032 17.3 12.8 1 9.8 0.0 6.9 7 0 0 7 7 7 1 Leucine rich repeat DUF2528 PF10800.3 EKE40710.1 - 0.028 14.7 0.1 0.079 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) LRR_4 PF12799.2 EKE40710.1 - 0.034 13.7 9.0 0.076 12.6 0.5 4.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) HIT PF01230.18 EKE40711.1 - 7.1e-28 97.0 0.1 8e-28 96.8 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EKE40711.1 - 1.3e-25 89.8 0.0 1.5e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EKE40711.1 - 0.0036 16.9 0.2 0.0038 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DEAD PF00270.24 EKE40712.1 - 2.7e-45 153.8 3.1 1.9e-44 151.1 0.7 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE40712.1 - 6.4e-27 93.2 0.5 3.8e-26 90.7 0.2 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EKE40712.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_22 PF13401.1 EKE40712.1 - 0.0015 18.6 0.1 0.0054 16.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 EKE40712.1 - 0.0052 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EKE40712.1 - 0.03 14.0 0.3 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Helicase_RecD PF05127.9 EKE40712.1 - 0.047 13.3 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Helicase ResIII PF04851.10 EKE40712.1 - 0.047 13.5 0.1 0.15 11.9 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit WD40 PF00400.27 EKE40713.1 - 2.2e-11 43.1 0.0 2.5e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat MFS_1 PF07690.11 EKE40714.1 - 1.4e-19 70.0 39.0 3.8e-14 52.1 6.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EKE40714.1 - 3.2e-15 56.0 11.3 3.2e-15 56.0 7.8 2.6 3 0 0 3 3 3 1 Nodulin-like TLD PF07534.11 EKE40715.1 - 0.0035 17.3 2.1 0.009 16.0 1.4 1.6 1 0 0 1 1 1 1 TLD Mem_trans PF03547.13 EKE40715.1 - 0.019 13.2 2.6 0.028 12.7 1.8 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF1325 PF07039.6 EKE40715.1 - 0.027 14.0 1.0 0.29 10.7 0.0 2.5 2 1 0 2 2 2 0 SGF29 tudor-like domain Flagellin_N PF00669.15 EKE40715.1 - 0.32 10.7 3.0 0.69 9.6 2.1 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Vinculin PF01044.14 EKE40715.1 - 0.35 8.8 5.8 0.46 8.4 4.1 1.1 1 0 0 1 1 1 0 Vinculin family DUF1759 PF03564.10 EKE40715.1 - 0.71 9.6 8.9 0.13 12.1 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) MCPsignal PF00015.16 EKE40715.1 - 0.84 9.1 5.0 1.5 8.3 3.4 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CENP-Q PF13094.1 EKE40715.1 - 2 8.3 8.8 4.8 7.1 6.1 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3755 PF12579.3 EKE40715.1 - 2.1 7.7 6.2 3.6 7.0 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3755) zf-UBR PF02207.15 EKE40717.1 - 2e-18 65.8 14.3 2e-18 65.8 9.9 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) CBM_1 PF00734.13 EKE40719.1 - 0.75 9.5 9.3 0.28 10.8 3.1 2.9 2 0 0 2 2 2 0 Fungal cellulose binding domain DUF4164 PF13747.1 EKE40720.1 - 0.026 14.6 1.3 0.026 14.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) UPF0118 PF01594.11 EKE40720.1 - 0.54 9.1 5.5 0.47 9.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF20 Baculo_PEP_C PF04513.7 EKE40720.1 - 2.5 7.9 10.1 0.54 10.0 1.5 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.8 EKE40720.1 - 3.9 5.7 6.9 0.33 9.3 0.8 1.9 2 0 0 2 2 2 0 Tweety Toxin_52 PF15605.1 EKE40720.1 - 4.7 7.1 8.9 1.4 8.8 0.3 3.0 2 1 1 3 3 3 0 Putative toxin 52 DUF972 PF06156.8 EKE40720.1 - 5.7 7.3 14.0 0.63 10.4 2.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Striatin PF08232.7 EKE40720.1 - 6.4 7.0 11.9 0.13 12.5 2.6 2.2 2 1 0 2 2 2 0 Striatin family NPV_P10 PF05531.7 EKE40720.1 - 8.9 6.6 12.1 0.35 11.1 1.3 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein JAB PF01398.16 EKE40721.1 - 1.5e-24 85.9 0.0 2.3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EKE40721.1 - 1.9e-07 30.5 0.0 3.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EKE40721.1 - 0.00021 20.8 0.0 0.00039 19.9 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF775 PF05603.7 EKE40722.1 - 0.007 15.9 1.0 0.096 12.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF775) vATP-synt_E PF01991.13 EKE40723.1 - 4.8e-38 130.4 17.2 4.8e-38 130.4 12.0 1.2 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2315 PF10231.4 EKE40723.1 - 0.12 12.2 3.9 0.21 11.4 2.7 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Mu-like_Com PF10122.4 EKE40724.1 - 0.00019 20.3 0.6 0.00045 19.2 0.4 1.7 1 0 0 1 1 1 1 Mu-like prophage protein Com Ank_2 PF12796.2 EKE40725.1 - 7.4e-26 90.3 0.1 1.7e-15 57.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE40725.1 - 2.9e-19 68.6 0.0 3.5e-09 36.6 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE40725.1 - 8.3e-19 65.8 2.0 0.001 19.0 0.0 6.1 4 1 1 5 5 5 4 Ankyrin repeat Ank PF00023.25 EKE40725.1 - 1.9e-17 62.0 0.1 0.00036 20.2 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Bromodomain PF00439.20 EKE40725.1 - 2.4e-17 62.6 1.2 2.4e-17 62.6 0.8 2.4 2 0 0 2 2 2 1 Bromodomain Ank_4 PF13637.1 EKE40725.1 - 6.1e-14 52.0 1.2 3.9e-05 24.0 0.1 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 EKE40725.1 - 0.029 14.1 12.2 0.32 10.8 0.7 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF3447) SIR2 PF02146.12 EKE40726.1 - 9.2e-51 172.0 0.0 1.4e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EKE40726.1 - 0.12 12.1 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF1230 PF06799.6 EKE40727.1 - 2.1 8.1 5.8 0.34 10.7 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) DUF605 PF04652.11 EKE40727.1 - 3.6 6.8 30.2 0.014 14.8 14.8 1.5 2 0 0 2 2 2 0 Vta1 like VHP PF02209.14 EKE40728.1 - 3.2e-11 42.7 4.7 4e-11 42.4 1.8 2.3 2 0 0 2 2 2 1 Villin headpiece domain Gelsolin PF00626.17 EKE40728.1 - 1.7e-05 24.4 0.0 1.7e-05 24.4 0.0 3.5 4 0 0 4 4 4 1 Gelsolin repeat LRR_4 PF12799.2 EKE40729.1 - 0.08 12.5 15.1 0.12 12.0 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) SFTA2 PF15210.1 EKE40729.1 - 2.9 7.5 11.9 0.97 9.0 1.0 3.4 3 0 0 3 3 3 0 Surfactant-associated protein 2 MFS_1 PF07690.11 EKE40730.1 - 4.9e-33 114.2 13.0 1.4e-26 93.0 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EKE40730.1 - 7.9e-05 20.9 0.0 7.9e-05 20.9 0.0 1.4 2 0 0 2 2 2 1 Transmembrane secretion effector Bromodomain PF00439.20 EKE40731.1 - 2.8e-22 78.4 3.8 9.8e-22 76.6 0.1 3.1 2 1 1 3 3 3 1 Bromodomain BTB PF00651.26 EKE40731.1 - 2.6e-05 24.1 0.0 8.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain CTDII PF01556.13 EKE40732.1 - 3.7e-06 26.7 1.9 0.027 14.3 0.0 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain DUF1967 PF09269.6 EKE40732.1 - 0.094 12.3 0.2 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) ABM PF03992.11 EKE40733.1 - 2e-15 56.5 0.0 2.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.1 EKE40733.1 - 0.011 15.7 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) HapK PF11639.3 EKE40733.1 - 0.04 14.5 0.1 0.048 14.2 0.1 1.3 1 0 0 1 1 1 0 REDY-like protein HapK Pterin_4a PF01329.14 EKE40733.1 - 0.078 12.7 0.5 0.12 12.1 0.4 1.4 1 1 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase SHS2_Rpb7-N PF03876.12 EKE40735.1 - 8.6e-06 25.7 0.1 1.8e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EKE40735.1 - 1.9e-05 24.8 0.0 2.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.18 EKE40735.1 - 0.0003 20.8 0.6 0.00059 19.8 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain PX PF00787.19 EKE40736.1 - 4.7e-05 23.1 0.8 0.00022 20.9 0.1 2.6 2 0 0 2 2 2 1 PX domain EamA PF00892.15 EKE40737.1 - 1.4e-05 25.1 10.6 1.4e-05 25.1 7.4 3.8 3 1 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EKE40737.1 - 3.4e-05 23.0 7.2 8.1e-05 21.8 5.0 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EKE40737.1 - 0.0027 17.8 10.4 0.0027 17.8 7.2 3.6 3 2 1 4 4 4 1 Multidrug resistance efflux transporter DUF3119 PF11317.3 EKE40737.1 - 0.051 13.5 0.8 0.051 13.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3119) TPT PF03151.11 EKE40737.1 - 0.54 9.8 29.3 1.7 8.3 8.4 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family EAP30 PF04157.11 EKE40738.1 - 4.4e-31 107.7 0.5 5.2e-31 107.5 0.3 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Atg8 PF02991.11 EKE40738.1 - 0.12 12.3 0.6 0.81 9.7 0.0 2.4 1 1 2 3 3 3 0 Autophagy protein Atg8 ubiquitin like Cytokin_check_N PF10407.4 EKE40739.1 - 0.025 14.1 1.6 2.1 8.0 0.0 2.6 2 1 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus HTH_45 PF14947.1 EKE40739.1 - 0.059 13.1 0.7 0.21 11.4 0.2 2.2 1 1 1 2 2 2 0 Winged helix-turn-helix Arm PF00514.18 EKE40740.1 - 0.0012 18.6 2.6 23 4.9 0.0 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat UCH PF00443.24 EKE40741.1 - 4.8e-43 147.2 7.4 5.6e-43 146.9 5.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE40741.1 - 4.2e-08 32.9 9.2 1.3e-07 31.4 6.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRP7 PF12923.2 EKE40741.1 - 0.016 15.1 0.2 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Sec63 PF02889.11 EKE40742.1 - 8e-126 419.4 3.9 1.9e-62 211.3 0.9 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EKE40742.1 - 1.2e-55 187.5 3.5 1.4e-27 96.2 0.3 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EKE40742.1 - 1.1e-18 67.7 0.5 1.8e-08 34.4 0.0 3.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKE40742.1 - 1.7e-17 63.0 0.0 1.4e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKE40742.1 - 1.1e-09 37.5 2.7 5.8e-07 28.5 0.1 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_22 PF13401.1 EKE40742.1 - 1.1e-08 35.2 0.4 0.0025 17.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 EKE40742.1 - 1.8e-06 27.3 0.0 0.08 12.1 0.0 2.8 2 0 0 2 2 2 2 PhoH-like protein T2SE PF00437.15 EKE40742.1 - 8.7e-05 21.5 0.0 0.063 12.1 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.1 EKE40742.1 - 0.00048 19.8 0.0 0.74 9.6 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain DUF2075 PF09848.4 EKE40742.1 - 0.00084 18.4 0.1 0.45 9.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EKE40742.1 - 0.0014 18.8 4.4 0.6 10.3 0.5 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EKE40742.1 - 0.0071 15.8 0.2 10 5.4 0.0 3.6 3 0 0 3 3 3 1 AAA-like domain IstB_IS21 PF01695.12 EKE40742.1 - 0.015 14.7 0.2 9.6 5.5 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein RPA_interact_N PF14766.1 EKE40742.1 - 1.1 8.8 2.2 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Replication protein A interacting N-terminal PTEN_C2 PF10409.4 EKE40743.1 - 1.7e-08 34.2 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.22 EKE40743.1 - 7.1e-08 32.0 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EKE40743.1 - 6.9e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 EKE40743.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EKE40743.1 - 0.0023 18.2 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKE40743.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Reo_sigmaC PF04582.7 EKE40744.1 - 0.53 9.4 14.0 0.09 11.9 3.3 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Na_trans_assoc PF06512.8 EKE40745.1 - 0.22 11.4 23.3 0.49 10.3 16.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated La PF05383.12 EKE40746.1 - 2.3e-17 62.5 1.2 5.4e-17 61.3 0.1 2.2 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 EKE40746.1 - 7e-05 22.3 0.6 0.00014 21.4 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40746.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Dopey_N PF04118.9 EKE40747.1 - 2.2e-22 79.2 9.9 1.8e-21 76.1 6.9 2.6 1 0 0 1 1 1 1 Dopey, N-terminal W2 PF02020.13 EKE40748.1 - 1e-09 38.1 4.8 4.5e-09 36.1 3.4 2.2 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 EKE40748.1 - 2.5e-06 26.9 0.6 6.4e-06 25.6 0.4 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EKE40748.1 - 1.3e-05 24.4 11.9 0.02 14.3 0.8 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EKE40748.1 - 0.25 11.3 0.0 0.44 10.6 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain OSCP PF00213.13 EKE40749.1 - 0.075 12.8 0.6 4.2 7.2 0.0 2.7 2 1 0 2 2 2 0 ATP synthase delta (OSCP) subunit DUF1394 PF07159.7 EKE40750.1 - 1.7e-66 224.4 1.1 2.1e-66 224.1 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) CS PF04969.11 EKE40751.1 - 3.5e-17 62.7 4.2 6.3e-17 61.8 2.9 1.4 1 0 0 1 1 1 1 CS domain Apyrase PF06079.6 EKE40751.1 - 0.0074 15.4 0.3 0.0098 15.0 0.2 1.2 1 0 0 1 1 1 1 Apyrase MgsA_C PF12002.3 EKE40752.1 - 2.1e-37 128.4 0.0 4.4e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EKE40752.1 - 2.7e-18 66.4 3.3 1.2e-15 57.8 0.2 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKE40752.1 - 3e-14 52.6 0.1 2.6e-13 49.5 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKE40752.1 - 6.7e-07 29.5 4.6 4e-06 27.0 0.5 3.3 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKE40752.1 - 1.8e-06 27.7 0.0 4.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EKE40752.1 - 4.9e-06 26.1 0.1 0.00027 20.4 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EKE40752.1 - 7.9e-06 25.7 0.2 7.9e-06 25.7 0.1 3.3 2 1 1 4 4 3 1 AAA domain Zeta_toxin PF06414.7 EKE40752.1 - 9.1e-06 24.9 0.0 1.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 EKE40752.1 - 6.1e-05 23.0 0.1 0.00026 21.0 0.0 2.2 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EKE40752.1 - 8e-05 23.4 1.2 0.002 18.9 0.8 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKE40752.1 - 0.00017 21.6 0.3 0.18 11.7 0.0 2.7 1 1 2 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.16 EKE40752.1 - 0.00027 20.1 0.5 0.097 11.8 0.0 2.7 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EKE40752.1 - 0.00061 20.0 6.4 0.005 17.1 3.7 2.8 1 1 1 2 2 2 1 AAA domain ADK PF00406.17 EKE40752.1 - 0.0012 18.6 0.4 0.2 11.5 0.0 2.5 1 1 1 2 2 2 1 Adenylate kinase ABC_tran PF00005.22 EKE40752.1 - 0.0015 18.8 0.6 0.005 17.1 0.1 2.1 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 EKE40752.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EKE40752.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 EKE40752.1 - 0.0025 17.3 1.8 0.0047 16.4 0.0 2.3 3 1 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EKE40752.1 - 0.0031 17.1 0.1 0.31 10.5 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EKE40752.1 - 0.0031 17.2 0.0 0.0077 15.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EKE40752.1 - 0.0073 15.7 0.0 0.044 13.2 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein NB-ARC PF00931.17 EKE40752.1 - 0.037 12.8 2.6 0.15 10.9 0.7 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 EKE40752.1 - 0.04 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DDE_Tnp_IS1595 PF12762.2 EKE40752.1 - 0.041 13.7 1.1 1.1 9.0 0.0 2.9 2 1 1 3 3 3 0 ISXO2-like transposase domain DUF2075 PF09848.4 EKE40752.1 - 0.057 12.3 6.3 2.3 7.0 4.4 2.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EKE40752.1 - 0.11 11.8 0.0 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EKE40752.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 EKE40752.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 EKE40752.1 - 0.22 11.0 5.7 0.51 9.8 4.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKE40752.1 - 0.6 9.4 3.8 3.9 6.8 1.9 2.7 1 1 0 1 1 1 0 AAA-like domain ResIII PF04851.10 EKE40752.1 - 3 7.6 11.7 2.3 8.0 4.4 3.0 1 1 3 4 4 4 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EKE40752.1 - 4.5 6.9 8.3 1.3 8.6 0.2 3.3 2 1 2 4 4 4 0 NTPase WD40 PF00400.27 EKE40753.1 - 5.7e-07 29.1 14.8 0.0004 20.1 0.1 6.2 7 0 0 7 7 7 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EKE40753.1 - 0.0004 19.2 0.0 0.0019 17.0 0.0 1.8 1 1 0 2 2 2 1 Nup133 N terminal like PQQ_3 PF13570.1 EKE40753.1 - 0.0074 16.5 1.8 18 5.7 0.1 4.4 5 0 0 5 5 5 1 PQQ-like domain Beta_propel PF09826.4 EKE40753.1 - 0.03 12.6 0.0 0.043 12.1 0.0 1.1 1 0 0 1 1 1 0 Beta propeller domain DUF3591 PF12157.3 EKE40754.1 - 1.8e-79 267.3 0.5 1.8e-79 267.3 0.3 3.7 3 1 1 5 5 5 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EKE40754.1 - 1.8e-17 63.0 0.2 1.8e-17 63.0 0.2 2.9 3 0 0 3 3 3 1 Bromodomain Pkr1 PF08636.5 EKE40756.1 - 1.3e-07 31.5 2.4 1.6e-07 31.2 1.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF2177 PF09945.4 EKE40756.1 - 0.027 14.4 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) DUF1049 PF06305.6 EKE40756.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1414 PF07208.6 EKE40756.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) DUF167 PF02594.11 EKE40757.1 - 1.6e-26 92.0 0.3 2.5e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Cpn10 PF00166.16 EKE40758.1 - 2e-17 62.8 0.1 2.2e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit SpoA PF01052.15 EKE40758.1 - 0.063 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) DapH_N PF08503.5 EKE40760.1 - 0.21 11.7 1.3 0.96 9.6 0.2 2.3 1 1 1 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal DUF3984 PF13136.1 EKE40762.1 - 0.065 12.4 0.2 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) PAP2 PF01569.16 EKE40763.1 - 1.6e-20 73.1 3.4 1.6e-20 73.1 2.3 1.6 1 1 1 2 2 2 1 PAP2 superfamily 7TMR-DISM_7TM PF07695.6 EKE40763.1 - 0.023 14.3 15.8 0.023 14.3 3.9 2.4 2 0 0 2 2 2 0 7TM diverse intracellular signalling EIID-AGA PF03613.9 EKE40763.1 - 0.035 13.0 4.7 0.013 14.4 1.3 1.7 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component DUF2645 PF10840.3 EKE40763.1 - 0.057 13.5 3.0 0.16 12.1 2.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) DUF1761 PF08570.5 EKE40763.1 - 0.48 10.4 6.4 5.6 6.9 0.5 2.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1761) DUF2418 PF10332.4 EKE40763.1 - 1.8 8.8 5.2 1.2e+02 3.0 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF4131 PF13567.1 EKE40763.1 - 3.2 7.1 8.3 0.92 8.8 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2628 PF10947.3 EKE40763.1 - 6.4 6.6 8.1 1 9.1 1.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) RNB PF00773.14 EKE40764.1 - 3.3e-14 52.8 11.4 1.4e-10 40.9 1.2 3.8 2 1 0 3 3 3 2 RNB domain GAS PF13851.1 EKE40765.1 - 0.0018 17.5 57.0 0.13 11.4 33.2 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding KRAB PF01352.22 EKE40765.1 - 0.014 14.7 0.5 3.2 7.2 0.0 3.0 2 0 0 2 2 2 0 KRAB box LRR_4 PF12799.2 EKE40765.1 - 0.054 13.1 1.0 0.22 11.2 0.7 2.1 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Reo_sigmaC PF04582.7 EKE40765.1 - 0.074 12.2 7.9 0.27 10.3 0.4 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2937 PF11157.3 EKE40765.1 - 0.095 12.0 4.9 0.29 10.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF3584 PF12128.3 EKE40765.1 - 0.25 8.6 33.8 0.34 8.1 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_GP20 PF06810.6 EKE40765.1 - 0.36 10.2 53.0 1.8 8.0 23.3 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 EKE40765.1 - 0.36 10.8 50.1 0.86 9.6 5.9 5.4 4 1 2 6 6 6 0 bZIP transcription factor DivIC PF04977.10 EKE40765.1 - 0.38 10.2 57.0 0.21 11.0 8.7 5.2 1 1 3 5 5 5 0 Septum formation initiator DUF484 PF04340.7 EKE40765.1 - 0.84 9.0 8.3 1.1 8.6 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF484 DIT1_PvcA PF05141.7 EKE40765.1 - 1.5 8.0 18.2 0.16 11.2 7.0 2.1 1 1 1 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein DASH_Hsk3 PF08227.6 EKE40765.1 - 8.9 6.5 8.1 47 4.2 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like DUF1804 PF08822.6 EKE40765.1 - 9.9 5.8 12.5 0.55 9.9 3.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1804) Pkinase_Tyr PF07714.12 EKE40766.1 - 2.3e-42 144.8 0.2 3.2e-42 144.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40766.1 - 5.8e-42 143.6 0.4 8.1e-42 143.1 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EKE40766.1 - 1.3e-05 24.3 0.0 2.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like AA_permease_2 PF13520.1 EKE40767.1 - 3.7e-24 85.0 57.4 4.8e-24 84.6 35.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EKE40767.1 - 2.7e-12 45.8 47.6 5.5e-12 44.7 33.0 1.4 1 1 0 1 1 1 1 Amino acid permease DUF1628 PF07790.6 EKE40767.1 - 0.23 12.2 0.0 0.23 12.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1628) Shisa PF13908.1 EKE40768.1 - 0.00016 21.9 1.0 0.00081 19.6 0.0 2.3 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.11 EKE40768.1 - 0.00022 21.1 4.7 0.00042 20.2 3.2 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HemY_N PF07219.8 EKE40768.1 - 0.00078 18.9 0.1 0.00078 18.9 0.1 2.4 2 0 0 2 2 2 1 HemY protein N-terminus IncA PF04156.9 EKE40768.1 - 0.0089 15.6 21.0 0.018 14.6 14.6 1.5 1 0 0 1 1 1 1 IncA protein DUF1191 PF06697.7 EKE40768.1 - 0.0094 14.7 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EKE40768.1 - 0.014 15.7 0.8 0.014 15.7 0.5 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2749 PF10907.3 EKE40768.1 - 0.88 9.4 3.6 2.6 7.9 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF4389 PF14333.1 EKE40768.1 - 0.97 9.1 3.0 2.1 8.1 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) RCR PF12273.3 EKE40768.1 - 3.7 8.1 5.8 12 6.4 3.9 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Arm PF00514.18 EKE40769.1 - 0.0063 16.3 1.4 7.9 6.4 0.0 4.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat GSIII_N PF12437.3 EKE40772.1 - 1.2e-63 213.3 0.0 2.4e-63 212.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 EKE40772.1 - 6.4e-35 120.5 0.0 1.5e-34 119.2 0.0 1.5 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain DUF1048 PF06304.6 EKE40772.1 - 0.075 13.3 0.1 3.2 8.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) Pkinase PF00069.20 EKE40773.1 - 8.2e-72 241.4 0.7 4e-53 180.2 0.1 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40773.1 - 2e-43 148.3 0.0 4.6e-32 111.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKE40773.1 - 1.7e-05 23.9 0.0 0.071 12.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Filamin PF00630.14 EKE40774.1 - 6.1e-95 312.4 30.8 5.9e-23 81.3 5.2 5.5 5 1 0 5 5 5 5 Filamin/ABP280 repeat CH PF00307.26 EKE40774.1 - 5e-33 113.3 0.5 4.3e-15 55.6 0.3 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKE40774.1 - 1.4e-06 27.8 0.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain Neurexophilin PF06312.7 EKE40774.1 - 5.1e-06 25.8 0.0 0.026 13.7 0.0 2.7 3 0 0 3 3 3 2 Neurexophilin Big_1 PF02369.11 EKE40774.1 - 9.2e-05 22.2 0.3 4.3 7.3 0.0 4.3 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 1) Y_Y_Y PF07495.8 EKE40774.1 - 0.0049 16.6 0.7 1.7 8.4 0.1 4.2 3 1 1 4 4 4 1 Y_Y_Y domain EMP24_GP25L PF01105.19 EKE40774.1 - 0.073 12.7 1.7 23 4.6 0.0 3.4 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD Daxx PF03344.10 EKE40774.1 - 0.24 9.8 28.0 0.35 9.2 19.4 1.2 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EKE40774.1 - 0.29 10.4 28.2 0.65 9.3 19.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 EKE40774.1 - 3 6.5 26.0 5.7 5.6 18.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Zip PF02535.17 EKE40774.1 - 3.3 6.6 6.5 5.9 5.7 4.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PRP3 PF08572.5 EKE40775.1 - 2.7e-31 108.6 21.2 8.3e-31 107.0 14.7 1.9 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EKE40775.1 - 2.3e-06 27.3 2.3 2.3e-06 27.3 1.6 3.7 3 2 0 3 3 3 1 Protein of unknown function (DUF1115) Spt5-NGN PF03439.8 EKE40775.1 - 0.022 14.4 0.8 1.5 8.5 0.0 2.9 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section DDOST_48kD PF03345.9 EKE40777.1 - 1.5e-24 86.3 0.8 2.3e-16 59.3 0.1 2.5 1 1 2 3 3 3 2 Oligosaccharyltransferase 48 kDa subunit beta ABC_transp_aux PF09822.4 EKE40777.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system IF4E PF01652.13 EKE40779.1 - 3.8e-31 107.8 4.0 4.3e-31 107.6 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PulG PF11773.3 EKE40779.1 - 0.18 11.5 1.4 0.8 9.4 0.3 2.1 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Peptidase_C1 PF00112.18 EKE40780.1 - 0.0048 16.7 1.2 1 9.1 0.3 2.7 1 1 0 2 2 2 2 Papain family cysteine protease Ras PF00071.17 EKE40781.1 - 1.1e-09 37.8 0.1 0.00053 19.4 0.0 2.4 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EKE40781.1 - 0.013 16.0 0.0 2.3 8.7 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein RasGEF PF00617.14 EKE40782.1 - 5e-12 45.9 4.0 5e-12 45.9 2.8 1.9 2 0 0 2 2 2 1 RasGEF domain Imm5 PF14423.1 EKE40782.1 - 1.1 8.8 8.0 0.21 11.2 0.1 3.2 4 0 0 4 4 4 0 Immunity protein Imm5 RRM_1 PF00076.17 EKE40784.1 - 2.8e-10 39.6 0.0 3.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40784.1 - 8.2e-08 32.1 0.0 9.5e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40784.1 - 1.5e-05 24.7 0.1 1.9e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE40784.1 - 0.00078 19.1 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EKE40785.1 - 5.5e-17 61.1 0.0 1.2e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40785.1 - 6.1e-13 48.5 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40785.1 - 2.9e-08 33.4 0.0 5.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4283 PF14111.1 EKE40785.1 - 0.03 13.4 0.1 0.51 9.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4283) Neur_chan_memb PF02932.11 EKE40785.1 - 1.8 8.4 10.4 2.2 8.0 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 EKE40785.1 - 2.1 8.0 15.3 3 7.5 10.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GBP_C PF02841.9 EKE40785.1 - 2.3 7.3 23.1 2.9 7.0 16.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CDC45 PF02724.9 EKE40785.1 - 3.7 5.4 20.1 5.2 4.9 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EKE40785.1 - 4 5.0 14.4 4.3 4.9 10.0 1.1 1 0 0 1 1 1 0 Ycf1 Paramyxo_ncap PF00973.14 EKE40785.1 - 5 5.7 12.9 6.4 5.3 8.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NCKAP5 PF15246.1 EKE40785.1 - 5.2 6.3 23.8 7.2 5.8 16.5 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF4558 PF15104.1 EKE40785.1 - 5.7 6.9 15.2 60 3.6 9.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4558) Peptidase_U32 PF01136.14 EKE40786.1 - 0.028 13.3 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 RasGEF PF00617.14 EKE40787.1 - 5.3e-36 124.1 0.0 1.4e-35 122.7 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE40787.1 - 0.0011 19.0 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Pkinase_Tyr PF07714.12 EKE40788.1 - 9.9e-07 28.0 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MCPsignal PF00015.16 EKE40789.1 - 0.025 14.1 0.3 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1116 PF06545.6 EKE40789.1 - 0.042 12.9 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1116) MT0933_antitox PF14013.1 EKE40789.1 - 0.33 11.0 28.3 0.2 11.7 3.5 5.3 3 2 2 5 5 5 0 MT0933-like antitoxin protein Pkinase PF00069.20 EKE40790.1 - 5.9e-46 156.7 0.1 1.3e-45 155.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40790.1 - 1.4e-33 116.1 0.0 2.5e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE40790.1 - 0.0048 15.8 0.0 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EKE40791.1 - 1.5e-72 243.9 0.0 2.1e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40791.1 - 1.9e-37 128.7 0.0 2.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE40791.1 - 2.2e-18 66.3 0.6 6e-18 64.9 0.1 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EKE40791.1 - 2e-09 37.6 0.8 3e-08 33.8 0.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EKE40791.1 - 5.5e-07 29.4 0.1 1.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EKE40791.1 - 3.9e-06 26.0 0.0 0.00012 21.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like PH_6 PF15406.1 EKE40791.1 - 4.5e-05 23.4 0.1 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.9 EKE40791.1 - 0.00038 19.5 0.0 0.0082 15.2 0.0 2.7 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE40791.1 - 0.00054 19.7 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PH_4 PF15404.1 EKE40791.1 - 0.0039 16.7 0.1 0.12 11.9 0.0 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.5 EKE40791.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Plant pleckstrin homology-like region Mcp5_PH PF12814.2 EKE40791.1 - 0.029 14.2 0.9 0.048 13.5 0.0 1.8 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology YrbL-PhoP_reg PF10707.4 EKE40791.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_C PF00433.19 EKE40791.1 - 0.15 12.6 0.9 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein kinase C terminal domain Peptidase_C48 PF02902.14 EKE40792.1 - 2e-22 79.9 4.8 3.2e-22 79.2 3.3 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YjeF_N PF03853.10 EKE40792.1 - 0.0044 16.6 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus AAA_35 PF14516.1 EKE40792.1 - 0.0063 15.1 0.3 0.013 14.2 0.2 1.5 1 0 0 1 1 1 1 AAA-like domain DUF1863 PF08937.6 EKE40792.1 - 1.3 9.0 6.9 1.6 8.8 0.0 3.2 3 1 0 3 3 3 0 MTH538 TIR-like domain (DUF1863) LisH PF08513.6 EKE40793.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.9 1 0 0 1 1 1 0 LisH RicinB_lectin_2 PF14200.1 EKE40794.1 - 1.7e-19 70.0 0.0 1.1e-18 67.5 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EKE40794.1 - 0.016 15.2 1.0 0.049 13.6 0.7 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Rap_GAP PF02145.10 EKE40795.1 - 2.4e-47 160.7 0.5 2.4e-47 160.7 0.3 2.7 4 0 0 4 4 4 1 Rap/ran-GAP FMN_red PF03358.10 EKE40797.1 - 2.3e-34 118.0 0.0 3.1e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EKE40797.1 - 5.5e-12 45.6 0.0 7.5e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EKE40797.1 - 0.016 15.2 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain GAGA_bind PF06217.7 EKE40798.1 - 0.25 11.2 10.3 0.32 10.9 7.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Tyrosinase PF00264.15 EKE40798.1 - 1.1 9.4 4.8 1.2 9.2 3.4 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase SLY PF12485.3 EKE40798.1 - 4.4 7.5 10.4 6.9 6.8 7.2 1.3 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Neur_chan_memb PF02932.11 EKE40798.1 - 5.6 6.7 8.7 6.4 6.5 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.5 EKE40798.1 - 5.9 4.7 11.1 6.6 4.6 7.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Peptidase_C1 PF00112.18 EKE40799.1 - 2e-05 24.5 15.3 5.2e-05 23.2 7.4 2.9 2 1 0 2 2 2 1 Papain family cysteine protease MAP1B_neuraxin PF00414.12 EKE40799.1 - 0.027 13.7 0.2 0.078 12.3 0.2 1.8 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat GCV_H PF01597.14 EKE40800.1 - 1.5e-06 27.8 0.1 4.1e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Glycine cleavage H-protein WWE PF02825.15 EKE40801.1 - 9.2e-09 34.6 1.9 2.1e-08 33.4 1.3 1.6 1 0 0 1 1 1 1 WWE domain DRY_EERY PF09750.4 EKE40801.1 - 0.032 14.3 2.2 6 6.9 0.1 2.4 2 0 0 2 2 2 0 Alternative splicing regulator TLP-20 PF06088.6 EKE40801.1 - 0.26 10.9 8.1 0.6 9.7 5.6 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PRP1_N PF06424.7 EKE40801.1 - 0.34 11.2 4.7 0.99 9.7 3.3 1.7 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal RasGEF PF00617.14 EKE40802.1 - 2.7e-18 66.3 3.6 2.7e-18 66.3 2.5 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE40802.1 - 0.11 12.5 3.3 0.13 12.4 0.4 2.7 3 0 0 3 3 3 0 RasGEF N-terminal motif TRP_N PF14558.1 EKE40803.1 - 0.003 17.5 0.0 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 ML-like domain RhoGEF PF00621.15 EKE40806.1 - 2.2e-37 128.6 0.2 2.2e-37 128.6 0.1 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF1371 PF07115.6 EKE40806.1 - 0.014 15.5 0.4 0.029 14.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1371) DUF3887 PF13026.1 EKE40806.1 - 0.019 15.2 0.2 0.041 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) IQ PF00612.22 EKE40806.1 - 0.1 12.2 0.2 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif CorA PF01544.13 EKE40807.1 - 8.2e-46 156.3 7.4 1e-45 156.0 5.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PSS PF03034.10 EKE40807.1 - 0.039 13.3 0.7 0.076 12.4 0.5 1.4 1 0 0 1 1 1 0 Phosphatidyl serine synthase Poty_PP PF08440.5 EKE40808.1 - 0.042 12.9 1.1 0.05 12.6 0.7 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein Mt_ATP-synt_D PF05873.7 EKE40808.1 - 0.045 13.4 0.8 0.062 12.9 0.6 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Striatin PF08232.7 EKE40808.1 - 0.095 13.0 4.8 0.13 12.5 3.3 1.1 1 0 0 1 1 1 0 Striatin family DUF1690 PF07956.6 EKE40808.1 - 0.11 12.4 4.5 0.16 11.9 3.1 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) AMP-binding_C_2 PF14535.1 EKE40808.1 - 0.12 12.4 1.6 0.23 11.5 1.1 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AKNA PF12443.3 EKE40808.1 - 0.12 12.3 1.9 0.19 11.7 1.3 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor TMPIT PF07851.8 EKE40808.1 - 0.85 8.6 4.1 1.2 8.1 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein ACCA PF03255.9 EKE40809.1 - 0.08 12.4 1.0 0.41 10.1 0.2 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Paralemmin PF03285.10 EKE40809.1 - 0.12 11.8 1.5 0.19 11.1 1.1 1.3 1 1 0 1 1 1 0 Paralemmin Peptidase_C50 PF03568.12 EKE40810.1 - 4.4e-64 216.5 0.4 3.6e-63 213.5 0.3 1.9 1 1 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 EKE40810.1 - 2.9e-06 26.6 0.0 0.00064 18.9 0.0 2.1 1 1 1 2 2 2 2 CHAT domain NAP PF00956.13 EKE40811.1 - 2.7e-15 56.1 8.0 3.5e-15 55.8 5.5 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) I_LWEQ PF01608.12 EKE40811.1 - 0.6 10.0 4.1 0.14 12.1 0.6 1.5 2 0 0 2 2 2 0 I/LWEQ domain Band_7_1 PF13421.1 EKE40812.1 - 0.086 12.3 2.2 0.097 12.1 1.5 1.1 1 0 0 1 1 1 0 SPFH domain-Band 7 family IncA PF04156.9 EKE40812.1 - 0.14 11.7 8.7 0.17 11.4 6.0 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EKE40812.1 - 0.21 10.4 11.6 0.25 10.2 8.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tnp_P_element PF12017.3 EKE40812.1 - 0.24 10.6 8.0 0.2 10.8 4.8 1.4 1 1 0 1 1 1 0 Transposase protein DUF4071 PF13281.1 EKE40812.1 - 0.53 9.0 10.3 0.56 8.9 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF1672 PF07901.6 EKE40812.1 - 0.69 8.8 9.3 0.8 8.6 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) DUF3391 PF11871.3 EKE40812.1 - 0.7 10.1 6.4 1 9.5 4.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) MS_channel PF00924.13 EKE40812.1 - 1.2 8.4 4.3 1.5 8.0 3.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel DUF724 PF05266.9 EKE40812.1 - 1.3 8.6 13.3 1.5 8.4 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GBP_C PF02841.9 EKE40812.1 - 1.3 8.1 16.7 1.5 7.9 11.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DWNN PF08783.6 EKE40812.1 - 1.4 8.8 6.9 0.33 10.9 0.8 2.2 2 1 0 2 2 2 0 DWNN domain DUF342 PF03961.8 EKE40812.1 - 1.6 7.0 15.3 1.8 6.8 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF607 PF04678.8 EKE40812.1 - 2 8.3 6.2 2.3 8.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF2443 PF10398.4 EKE40812.1 - 2 8.2 7.9 1.3 8.8 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) DUF3450 PF11932.3 EKE40812.1 - 2.1 7.5 12.9 3 7.0 8.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.4 EKE40812.1 - 2.1 8.5 15.3 1.5 9.0 5.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EKE40812.1 - 2.6 6.3 16.9 2.8 6.2 11.7 1.1 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EKE40812.1 - 2.8 8.4 6.0 2 8.8 3.1 1.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bap31 PF05529.7 EKE40812.1 - 2.9 7.2 14.0 4.9 6.5 9.7 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like TMPIT PF07851.8 EKE40812.1 - 4.3 6.3 10.6 4.6 6.2 7.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein SseC PF04888.7 EKE40812.1 - 5 6.3 14.0 5.9 6.1 8.1 1.9 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family MRP-S26 PF14943.1 EKE40812.1 - 5.8 6.4 18.8 6.5 6.2 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 YlbD_coat PF14071.1 EKE40812.1 - 6 6.9 13.5 13 5.8 9.3 1.7 1 1 0 1 1 1 0 Putative coat protein I_LWEQ PF01608.12 EKE40812.1 - 7 6.5 11.2 11 5.9 7.5 1.5 1 1 0 1 1 1 0 I/LWEQ domain Med9 PF07544.8 EKE40812.1 - 9.5 6.0 14.7 5.4 6.8 6.6 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HAD_2 PF13419.1 EKE40814.1 - 5.1e-19 69.1 0.0 6.4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE40814.1 - 1.1e-12 48.7 0.8 4e-12 47.0 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE40814.1 - 1.4e-08 35.0 0.1 2.8e-08 34.1 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EKE40814.1 - 0.00013 21.7 0.3 0.0062 16.4 0.2 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.7 EKE40814.1 - 0.0045 16.5 0.1 0.0091 15.5 0.1 1.7 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_like PF13242.1 EKE40814.1 - 0.0064 16.1 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EKE40814.1 - 0.0075 15.9 0.7 0.056 13.0 0.5 2.2 1 1 0 1 1 1 1 Acid Phosphatase Fer4_12 PF13353.1 EKE40814.1 - 0.021 14.9 0.2 0.042 13.9 0.1 1.6 1 1 0 1 1 1 0 4Fe-4S single cluster domain GDPD PF03009.12 EKE40814.1 - 0.054 12.9 0.4 0.098 12.1 0.2 1.3 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Hydrolase_3 PF08282.7 EKE40814.1 - 0.33 10.4 7.8 74 2.7 5.4 3.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3377 PF11857.3 EKE40815.1 - 0.039 13.5 0.1 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.1 EKE40815.1 - 0.054 13.1 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family ANTH PF07651.11 EKE40816.1 - 2.7e-09 36.1 2.9 3.2e-09 35.9 2.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EKE40816.1 - 0.0012 18.6 2.0 0.0026 17.5 1.4 1.5 1 0 0 1 1 1 1 ENTH domain DUF3868 PF12984.2 EKE40817.1 - 0.021 14.3 0.1 0.092 12.2 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) EF-hand_1 PF00036.27 EKE40818.1 - 7.1e-24 81.2 11.9 3.3e-07 29.1 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 EKE40818.1 - 2.1e-22 78.9 7.5 4.8e-14 52.2 0.2 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EKE40818.1 - 5.5e-20 70.7 8.3 2e-08 33.6 0.5 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EKE40818.1 - 7.4e-18 62.7 12.4 6.8e-05 22.4 0.2 4.7 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKE40818.1 - 2.6e-17 61.3 6.9 1.1e-05 24.4 0.4 4.2 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EKE40818.1 - 8.4e-05 22.5 0.1 0.047 13.7 0.0 2.7 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKE40818.1 - 0.00011 21.8 1.1 0.049 13.3 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EKE40818.1 - 0.0055 16.5 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain Phage_Mu_Gam PF07352.7 EKE40818.1 - 0.031 13.8 0.2 0.065 12.7 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein EF-hand_10 PF14788.1 EKE40818.1 - 0.048 13.3 0.9 13 5.5 0.0 3.2 3 1 1 4 4 4 0 EF hand START PF01852.14 EKE40819.1 - 2e-12 46.8 0.0 2.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE40819.1 - 0.00022 20.8 0.5 0.00081 19.0 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3074) C2 PF00168.25 EKE40822.1 - 1.2e-13 50.7 0.1 6e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 C2 domain PPC PF04151.10 EKE40823.1 - 0.091 13.7 0.3 50 4.9 0.0 3.6 3 1 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Metallophos PF00149.23 EKE40824.1 - 6.6e-08 32.1 5.9 3.5e-07 29.8 4.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EKE40825.1 - 2.7e-07 30.2 9.3 0.17 11.7 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat F-box PF00646.28 EKE40825.1 - 0.0092 15.6 2.3 0.0092 15.6 1.6 2.5 3 0 0 3 3 3 1 F-box domain Pkinase PF00069.20 EKE40827.1 - 3.6e-52 177.0 0.0 7.9e-52 175.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40827.1 - 4.5e-17 61.9 0.0 6.7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE40827.1 - 1.9e-05 24.5 0.0 3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKE40827.1 - 0.00014 21.2 0.4 0.0035 16.7 0.0 2.2 1 1 1 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EKE40827.1 - 0.0031 17.1 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF912 PF06024.7 EKE40828.1 - 0.0029 17.6 0.1 0.0078 16.2 0.0 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S41 PF03572.13 EKE40828.1 - 0.0033 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Rax2 PF12768.2 EKE40828.1 - 0.0052 16.0 0.8 0.011 14.9 0.5 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.1 EKE40828.1 - 0.0077 15.9 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family Pex14_N PF04695.8 EKE40828.1 - 0.017 15.1 0.5 0.04 13.9 0.1 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1191 PF06697.7 EKE40828.1 - 0.043 12.6 0.1 0.078 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Podoplanin PF05808.6 EKE40828.1 - 0.091 12.3 0.4 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Podoplanin stn_TNFRSF12A PF12191.3 EKE40828.1 - 0.3 11.1 4.2 0.56 10.2 2.9 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CARDB PF07705.6 EKE40828.1 - 0.31 11.1 4.1 11 6.1 2.0 3.3 2 1 0 2 2 2 0 CARDB APG6 PF04111.7 EKE40829.1 - 1.2e-42 146.0 12.5 1.2e-42 146.0 8.7 1.3 2 0 0 2 2 2 1 Autophagy protein Apg6 DUF342 PF03961.8 EKE40829.1 - 0.24 9.8 8.5 0.45 8.8 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 EKE40829.1 - 0.49 10.7 9.1 4.4 7.6 0.5 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Kri1 PF05178.7 EKE40829.1 - 0.85 9.9 7.5 58 4.0 3.0 2.6 1 1 0 1 1 1 0 KRI1-like family MA3 PF02847.12 EKE40829.1 - 2.3 7.9 8.7 0.92 9.2 0.9 3.2 3 1 1 4 4 4 0 MA3 domain DUF2458 PF10454.4 EKE40829.1 - 3.5 7.5 12.4 3.8 7.3 2.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) WD40 PF00400.27 EKE40830.1 - 5.7e-49 162.3 12.4 1.3e-10 40.7 0.4 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EKE40830.1 - 4.7e-47 160.7 8.5 3.8e-44 151.2 4.4 2.2 1 1 1 2 2 2 2 Coatomer WD associated region YmzC PF14157.1 EKE40830.1 - 0.007 16.1 0.0 7.4 6.4 0.0 3.8 4 0 0 4 4 4 1 YmzC-like protein Clathrin PF00637.15 EKE40830.1 - 0.054 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Region in Clathrin and VPS ThiF PF00899.16 EKE40831.1 - 2.9e-39 133.9 0.2 4.7e-39 133.3 0.2 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EKE40831.1 - 5.4e-24 83.6 3.1 8.8e-24 82.9 0.9 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain 2-Hacid_dh_C PF02826.14 EKE40831.1 - 0.00014 21.0 0.2 0.00014 21.0 0.1 2.5 2 2 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EKE40831.1 - 0.0043 17.1 0.1 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 EKE40832.1 - 5.4e-31 105.3 17.9 9.3e-11 41.1 1.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EKE40832.1 - 1.2e-18 66.8 0.4 2.1e-18 66.0 0.3 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 EKE40832.1 - 1.6e-07 31.2 1.8 0.08 12.6 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ras PF00071.17 EKE40833.1 - 2.8e-07 30.0 0.4 5.2e-07 29.1 0.3 1.5 1 1 0 1 1 1 1 Ras family PduV-EutP PF10662.4 EKE40833.1 - 0.022 14.2 0.3 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EKE40833.1 - 0.024 15.1 0.1 0.058 13.8 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 EKE40833.1 - 0.044 13.3 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF3608 PF12257.3 EKE40834.1 - 4.1e-09 35.7 6.1 5.8e-09 35.2 1.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3608) DEP PF00610.16 EKE40834.1 - 0.0006 19.4 0.0 0.0019 17.9 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) R3H PF01424.17 EKE40835.1 - 1.1e-10 41.0 0.0 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 R3H domain Ricin_B_lectin PF00652.17 EKE40836.1 - 8.4e-11 41.9 0.0 9.9e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EKE40836.1 - 1.5e-10 41.3 0.0 1.1e-05 25.6 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like RNase_P_Rpp14 PF01900.14 EKE40837.1 - 0.0017 18.2 0.1 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Abhydrolase_5 PF12695.2 EKE40838.1 - 4.7e-07 29.6 0.0 9.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family SAM_2 PF07647.12 EKE40838.1 - 2.2e-05 24.1 0.0 0.00049 19.8 0.0 3.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EKE40838.1 - 8e-05 22.7 0.0 0.00031 20.8 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1863 PF08937.6 EKE40838.1 - 0.0017 18.4 0.8 0.014 15.4 0.0 2.6 2 0 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) Fcf1 PF04900.7 EKE40838.1 - 0.029 14.4 0.5 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Fcf1 Abhydrolase_3 PF07859.8 EKE40838.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fer4_NifH PF00142.13 EKE40838.1 - 0.085 12.0 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Metallophos PF00149.23 EKE40839.1 - 8.5e-29 100.3 0.4 1.3e-28 99.8 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE40839.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain V-ATPase_C PF03223.10 EKE40840.1 - 4.3e-76 256.2 5.4 4.6e-76 256.1 3.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF4458 PF14660.1 EKE40840.1 - 0.01 15.7 0.8 0.024 14.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) DUF3313 PF11769.3 EKE40841.1 - 0.18 11.1 8.7 0.31 10.3 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3313) MS_channel PF00924.13 EKE40841.1 - 0.91 8.8 3.2 1.7 7.9 2.2 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel Fer4_12 PF13353.1 EKE40841.1 - 1.5 8.9 4.9 13 5.8 1.5 2.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain Methyltransf_19 PF04672.7 EKE40842.1 - 0.0036 16.6 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_26 PF13659.1 EKE40842.1 - 0.044 13.8 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EKE40842.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RRM_1 PF00076.17 EKE40843.1 - 8.4e-17 60.5 0.1 1.2e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40843.1 - 2.3e-14 53.1 0.0 3.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40843.1 - 4.9e-06 26.2 0.1 8.2e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Imm3 PF14425.1 EKE40843.1 - 0.081 12.8 1.1 0.2 11.6 0.2 1.8 1 1 1 2 2 2 0 Immunity protein Imm3 tRNA-synt_2b PF00587.20 EKE40844.1 - 2.3e-34 118.4 0.0 4.7e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EKE40844.1 - 2.3e-20 72.6 4.5 5.4e-20 71.4 3.1 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EKE40844.1 - 0.0034 15.8 1.8 0.0047 15.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Occludin_ELL PF07303.8 EKE40844.1 - 0.51 11.1 4.5 3.8 8.3 1.0 2.5 2 0 0 2 2 2 0 Occludin homology domain Ras PF00071.17 EKE40848.1 - 1.3e-56 190.4 0.0 1.6e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40848.1 - 9.7e-16 58.3 0.0 2e-15 57.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE40848.1 - 5.8e-09 35.4 0.0 7.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE40848.1 - 0.0021 17.2 0.0 0.0035 16.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RRM_1 PF00076.17 EKE40849.1 - 2.7e-14 52.5 0.1 8e-06 25.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40849.1 - 2e-11 43.5 0.1 1.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40849.1 - 6.1e-11 42.1 0.1 1.3e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE40849.1 - 0.00088 18.9 0.1 0.006 16.3 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PRP38_assoc PF12871.2 EKE40849.1 - 0.0019 18.7 31.1 0.0019 18.7 21.6 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PH_10 PF15411.1 EKE40849.1 - 9.9 6.3 7.9 0.58 10.3 1.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_S41 PF03572.13 EKE40850.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 LRR_5 PF13306.1 EKE40851.1 - 1.8e-128 422.2 90.0 3e-36 123.9 6.1 7.6 5 2 2 7 7 7 7 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE40851.1 - 9.1e-56 185.4 43.7 1.2e-08 34.5 0.4 14.2 7 4 9 16 16 16 14 Leucine rich repeat LRR_4 PF12799.2 EKE40851.1 - 0.0015 18.0 28.2 0.0047 16.5 0.1 7.5 6 3 1 7 7 7 3 Leucine Rich repeats (2 copies) Ras PF00071.17 EKE40852.1 - 1.2e-20 73.5 1.6 1.5e-20 73.2 1.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40852.1 - 1.7e-11 44.6 1.2 6.4e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE40852.1 - 9.6e-06 24.9 0.5 4.1e-05 22.8 0.3 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE40852.1 - 0.0038 16.6 0.2 0.14 11.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EKE40852.1 - 0.063 12.0 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 ArgK protein TPR_12 PF13424.1 EKE40853.1 - 5.8e-10 38.9 2.3 0.2 11.6 0.0 5.7 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKE40853.1 - 2e-08 33.5 13.4 0.94 9.5 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EKE40853.1 - 4.6e-06 26.0 23.1 0.087 12.6 1.3 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKE40853.1 - 0.00013 21.5 11.2 4.5 6.9 0.0 5.5 5 1 1 6 6 6 4 TPR repeat TPR_7 PF13176.1 EKE40853.1 - 0.0093 15.7 2.1 22 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKE40853.1 - 0.011 15.3 23.6 0.45 10.1 0.5 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE40853.1 - 3.3 8.3 6.5 1.7e+02 3.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat IBR PF01485.16 EKE40854.1 - 7.8e-19 67.3 36.3 2.1e-10 40.3 8.3 4.5 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EKE40854.1 - 0.0015 18.3 12.4 0.0015 18.3 8.6 4.9 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE40854.1 - 0.017 15.0 15.1 0.017 15.0 10.4 5.9 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF2098 PF09871.4 EKE40854.1 - 2.4 8.1 9.5 5.7 6.9 6.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) TLD PF07534.11 EKE40855.1 - 3.2e-22 79.0 0.6 5.8e-22 78.1 0.4 1.4 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 EKE40855.1 - 0.002 17.6 1.7 0.0027 17.2 0.5 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Got1 PF04178.7 EKE40857.1 - 2.5e-22 79.2 21.1 3.3e-22 78.8 14.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family MMS19_N PF14500.1 EKE40859.1 - 2.3e-39 135.2 4.0 2.3e-39 135.2 2.8 2.4 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 EKE40859.1 - 2.4 8.7 4.5 22 5.6 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat DAGK_acc PF00609.14 EKE40860.1 - 4.7e-34 117.8 0.0 7.2e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EKE40860.1 - 3.5e-19 68.5 0.0 5.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EKE40860.1 - 2.8e-17 62.1 49.6 6.8e-13 48.1 4.2 3.6 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 EKE40860.1 - 0.019 15.0 7.0 0.019 15.0 4.9 3.9 3 1 0 3 3 3 0 C1 domain NAD_kinase PF01513.16 EKE40860.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Ras PF00071.17 EKE40861.1 - 5.4e-48 162.4 0.2 6.6e-48 162.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40861.1 - 1.1e-19 71.0 0.0 2.8e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE40861.1 - 1.3e-14 53.8 0.1 1.6e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE40861.1 - 1.5e-09 37.5 0.1 2.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE40861.1 - 1e-08 34.6 0.1 1.1e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE40861.1 - 4.8e-06 26.5 0.0 7.3e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE40861.1 - 0.029 13.6 0.2 3.9 6.7 0.0 2.6 2 1 1 3 3 3 0 Ferrous iron transport protein B Peroxin-22 PF12827.2 EKE40861.1 - 0.094 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family PduV-EutP PF10662.4 EKE40861.1 - 0.14 11.6 0.4 0.29 10.5 0.3 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FHA PF00498.21 EKE40862.1 - 4.2e-06 26.7 0.2 8.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 FHA domain LMBR1 PF04791.11 EKE40862.1 - 1.8 7.0 4.2 2.3 6.7 2.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DPBB_1 PF03330.13 EKE40863.1 - 0.00013 21.9 0.6 0.00042 20.2 0.1 2.2 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RhoGAP PF00620.22 EKE40864.1 - 3.8e-18 65.5 0.0 3.8e-18 65.5 0.0 2.3 3 0 0 3 3 3 1 RhoGAP domain Helicase_C_4 PF13871.1 EKE40864.1 - 0.66 9.3 3.2 0.31 10.4 0.5 1.6 2 0 0 2 2 2 0 Helicase_C-like Tic20 PF09685.5 EKE40865.1 - 1.9 8.5 12.5 2.5 8.1 8.6 1.3 1 0 0 1 1 1 0 Tic20-like protein YoqO PF14037.1 EKE40865.1 - 2.6 8.1 16.0 3.6 7.7 10.8 1.4 1 1 0 1 1 1 0 YoqO-like protein MBOAT PF03062.14 EKE40866.1 - 4e-26 91.8 21.2 4e-26 91.8 14.7 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DEAD PF00270.24 EKE40867.1 - 4.9e-45 153.0 0.0 1.7e-44 151.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE40867.1 - 2.1e-26 91.5 0.0 5.5e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKE40867.1 - 0.00079 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EKE40867.1 - 0.0008 19.2 0.0 0.0024 17.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M24 PF00557.19 EKE40868.1 - 6.8e-22 78.0 0.4 8.6e-22 77.7 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 APG9 PF04109.11 EKE40869.1 - 1.6e-06 27.3 0.9 2e-06 26.9 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 HSF_DNA-bind PF00447.12 EKE40869.1 - 0.025 14.7 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 HSF-type DNA-binding Bacillus_HBL PF05791.6 EKE40869.1 - 0.049 13.0 0.9 0.075 12.4 0.6 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Halogen_Hydrol PF10112.4 EKE40869.1 - 0.071 12.5 0.2 0.09 12.1 0.1 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SdpI PF13630.1 EKE40869.1 - 7 6.4 6.7 13 5.6 4.6 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family ASFV_J13L PF05568.6 EKE40870.1 - 1.5 8.3 3.3 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein Glu_cyclase_2 PF05096.7 EKE40871.1 - 7.5e-53 179.2 0.2 1.2e-52 178.5 0.1 1.3 1 1 0 1 1 1 1 Glutamine cyclotransferase Lgl_C PF08596.5 EKE40871.1 - 0.0068 14.9 0.0 0.0091 14.5 0.0 1.1 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal RRM_1 PF00076.17 EKE40872.1 - 7.3e-09 35.1 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40872.1 - 7.7e-06 25.7 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE40872.1 - 0.0009 19.0 0.1 0.002 17.9 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MitMem_reg PF13012.1 EKE40873.1 - 0.017 15.1 1.1 0.019 15.0 0.8 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function TFIID_20kDa PF03847.8 EKE40873.1 - 0.039 14.2 0.3 0.051 13.8 0.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RasGAP PF00616.14 EKE40873.1 - 0.072 12.7 0.2 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase BLOC1_2 PF10046.4 EKE40873.1 - 0.089 12.9 0.5 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3685 PF12452.3 EKE40873.1 - 0.11 11.6 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF4546 PF15079.1 EKE40873.1 - 0.2 10.7 2.4 0.22 10.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) DUF2262 PF10020.4 EKE40873.1 - 0.25 11.5 5.4 0.29 11.3 3.8 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DegQ PF08181.6 EKE40873.1 - 0.55 9.9 4.0 0.3 10.8 1.0 1.9 2 1 0 2 2 2 0 DegQ (SacQ) family GN3L_Grn1 PF08701.6 EKE40874.1 - 1.2 9.0 8.6 1.6 8.6 6.0 1.3 1 1 0 1 1 1 0 GNL3L/Grn1 putative GTPase LRR_5 PF13306.1 EKE40875.1 - 4.8e-71 236.5 29.1 2.2e-34 117.9 4.1 4.2 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE40875.1 - 1e-25 89.1 25.7 9.3e-09 34.9 0.5 7.0 3 2 2 6 6 6 6 Leucine rich repeat DUF4513 PF14983.1 EKE40875.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) Thioredoxin PF00085.15 EKE40876.1 - 3.2e-09 36.3 4.3 1.7e-06 27.6 0.1 3.2 3 0 0 3 3 3 2 Thioredoxin HSP70 PF00012.15 EKE40877.1 - 8.6e-109 364.1 18.7 6e-97 325.0 4.9 2.2 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EKE40877.1 - 2.3e-19 69.1 7.5 6.9e-19 67.6 4.1 2.4 2 1 0 2 2 2 1 MreB/Mbl protein TrwC PF08751.6 EKE40877.1 - 0.00025 20.5 0.9 0.00058 19.3 0.1 2.0 2 0 0 2 2 2 1 TrwC relaxase BcrAD_BadFG PF01869.15 EKE40877.1 - 0.0021 17.4 0.2 0.071 12.3 0.0 2.8 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 EKE40877.1 - 0.0023 17.0 2.0 0.0051 15.9 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase Sec20 PF03908.8 EKE40877.1 - 0.069 12.8 1.9 0.33 10.6 1.3 2.1 1 0 0 1 1 1 0 Sec20 FtsA PF14450.1 EKE40877.1 - 0.22 11.3 11.1 6.1 6.7 3.3 3.8 2 2 1 3 3 3 0 Cell division protein FtsA PI3_PI4_kinase PF00454.22 EKE40878.1 - 1.5e-12 47.4 1.8 1.3e-09 37.8 0.1 2.8 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Fe-ADH PF00465.14 EKE40879.1 - 1.8e-74 250.5 0.0 2.2e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKE40879.1 - 3e-08 33.2 0.4 1.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EKE40879.1 - 0.6 8.9 3.4 13 4.5 0.6 2.5 2 1 0 2 2 2 0 3-dehydroquinate synthase zf-C2H2 PF00096.21 EKE40880.1 - 5.9e-24 82.9 45.8 4.8e-05 23.4 0.7 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKE40880.1 - 1.4e-17 62.6 44.3 0.00052 20.1 0.5 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKE40880.1 - 3.3e-12 46.0 59.3 8.7e-05 22.6 0.8 8.6 8 1 0 8 8 8 5 Zinc-finger double domain zf-Di19 PF05605.7 EKE40880.1 - 2.5e-05 24.3 47.5 0.38 10.9 1.0 6.4 3 2 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding DUF1610 PF07754.6 EKE40880.1 - 0.006 16.6 0.2 0.006 16.6 0.1 5.4 7 0 0 7 7 7 1 Domain of unknown function (DUF1610) TF_Zn_Ribbon PF08271.7 EKE40880.1 - 0.089 12.1 13.0 0.054 12.8 1.3 4.1 3 1 1 4 4 4 0 TFIIB zinc-binding zf-ISL3 PF14690.1 EKE40880.1 - 0.43 10.6 11.2 7.1 6.7 0.2 4.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_jaz PF12171.3 EKE40880.1 - 0.5 10.5 0.1 0.5 10.5 0.0 5.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding PhnJ PF06007.6 EKE40880.1 - 4.5 5.9 9.5 0.075 11.7 0.8 2.2 2 1 0 3 3 3 0 Phosphonate metabolism protein PhnJ WhiA_N PF10298.4 EKE40881.1 - 0.075 12.8 0.7 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain OTOS PF15182.1 EKE40881.1 - 0.14 11.8 1.1 0.54 9.9 0.2 2.3 2 0 0 2 2 2 0 Otospiralin DUF1323 PF07037.6 EKE40881.1 - 0.18 12.0 0.2 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) TIP49 PF06068.8 EKE40882.1 - 7.9e-161 535.2 1.3 9.1e-161 535.0 0.9 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EKE40882.1 - 3.8e-12 45.7 0.6 2.1e-07 30.2 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EKE40882.1 - 7.8e-12 45.5 0.3 5.5e-08 33.0 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE40882.1 - 2.5e-09 37.3 0.1 6.5e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EKE40882.1 - 1.3e-08 35.0 0.2 0.0067 16.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EKE40882.1 - 1.1e-06 28.4 0.1 0.0024 17.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EKE40882.1 - 7.2e-06 26.3 0.1 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EKE40882.1 - 3.2e-05 23.1 0.4 0.0029 16.7 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EKE40882.1 - 4.3e-05 23.4 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKE40882.1 - 4.8e-05 24.1 0.0 0.0001 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EKE40882.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EKE40882.1 - 0.00052 19.5 0.1 0.2 11.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EKE40882.1 - 0.00083 18.5 0.2 0.0015 17.6 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EKE40882.1 - 0.00096 19.0 0.0 0.0072 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKE40882.1 - 0.00099 18.8 1.0 0.0021 17.7 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EKE40882.1 - 0.0011 18.4 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EKE40882.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.9 EKE40882.1 - 0.0019 17.1 0.0 0.45 9.4 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UPF0079 PF02367.12 EKE40882.1 - 0.002 17.7 0.1 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DnaB_C PF03796.10 EKE40882.1 - 0.005 15.7 0.1 0.0088 14.9 0.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RNA_helicase PF00910.17 EKE40882.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 EKE40882.1 - 0.0072 16.3 0.0 0.06 13.4 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EKE40882.1 - 0.0074 15.8 0.0 0.022 14.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EKE40882.1 - 0.011 15.1 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EKE40882.1 - 0.016 14.7 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 EKE40882.1 - 0.018 14.0 0.1 0.037 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EKE40882.1 - 0.02 14.0 0.2 0.086 11.9 0.1 2.1 2 1 0 2 2 2 0 KaiC AAA_32 PF13654.1 EKE40882.1 - 0.03 13.0 1.1 0.3 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EKE40882.1 - 0.035 13.0 0.8 0.04 12.8 0.0 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EKE40882.1 - 0.044 13.3 0.2 0.48 9.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EKE40882.1 - 0.046 13.2 0.1 0.25 10.8 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EKE40882.1 - 0.048 13.1 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF853 PF05872.7 EKE40882.1 - 0.049 11.9 0.1 0.049 11.9 0.0 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) KTI12 PF08433.5 EKE40882.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 EKE40882.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 EKE40882.1 - 0.087 12.6 1.3 1.5 8.6 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Miro PF08477.8 EKE40882.1 - 0.089 13.2 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Viral_helicase1 PF01443.13 EKE40882.1 - 0.11 11.9 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zot PF05707.7 EKE40882.1 - 0.11 11.9 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) LSM PF01423.17 EKE40885.1 - 1.8e-16 59.4 0.0 2.1e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4156 PF13698.1 EKE40886.1 - 0.011 15.6 0.4 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) UPF0118 PF01594.11 EKE40886.1 - 1.3 7.9 3.8 1.7 7.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 IMS PF00817.15 EKE40887.1 - 0.0024 17.6 0.1 0.0026 17.5 0.1 1.1 1 0 0 1 1 1 1 impB/mucB/samB family DUF4596 PF15363.1 EKE40887.1 - 0.31 10.9 3.2 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) PIF1 PF05970.9 EKE40889.1 - 1e-53 182.5 7.0 4.1e-45 154.3 0.5 3.0 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EKE40889.1 - 3.1e-15 56.2 0.0 4.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKE40889.1 - 5e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EKE40889.1 - 0.0069 16.5 0.1 0.31 11.1 0.0 3.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EKE40889.1 - 0.02 14.1 0.0 0.044 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 EKE40889.1 - 0.026 14.7 0.1 0.064 13.4 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EKE40889.1 - 0.026 13.6 0.2 0.062 12.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EKE40889.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EKE40889.1 - 0.027 14.6 0.2 0.14 12.2 0.1 2.4 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EKE40889.1 - 0.032 13.9 0.3 0.2 11.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FliC_SP PF12613.3 EKE40889.1 - 2.9 8.1 7.2 0.11 12.6 0.9 1.7 2 0 0 2 2 1 0 Flagellin structural protein SLAC1 PF03595.12 EKE40890.1 - 0.89 8.1 13.6 0.062 11.9 5.9 1.6 2 0 0 2 2 2 0 Voltage-dependent anion channel SK_channel PF03530.9 EKE40890.1 - 2.9 7.7 6.7 6.5 6.6 4.6 1.8 1 1 0 1 1 1 0 Calcium-activated SK potassium channel Ras PF00071.17 EKE40891.1 - 2e-51 173.5 0.1 2.5e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40891.1 - 8.4e-19 68.2 0.0 1.3e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40891.1 - 6.4e-11 41.7 0.0 7.5e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE40891.1 - 7.3e-08 31.8 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE40891.1 - 1.7e-07 30.8 0.0 6.3e-06 25.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE40891.1 - 5.9e-07 29.4 0.0 9e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKE40891.1 - 0.00054 19.1 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EKE40891.1 - 0.00088 19.0 0.1 0.0029 17.3 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase SRPRB PF09439.5 EKE40891.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EKE40891.1 - 0.0015 18.6 0.0 0.0045 17.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EKE40891.1 - 0.0017 18.3 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EKE40891.1 - 0.0038 16.8 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EKE40891.1 - 0.0063 15.5 0.1 0.019 13.9 0.0 1.8 2 0 0 2 2 2 1 Septin FeoB_N PF02421.13 EKE40891.1 - 0.0093 15.2 0.0 0.93 8.7 0.1 2.5 2 2 0 2 2 2 1 Ferrous iron transport protein B AAA_5 PF07728.9 EKE40891.1 - 0.01 15.5 0.0 0.041 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EKE40891.1 - 0.015 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PRK PF00485.13 EKE40891.1 - 0.017 14.7 0.1 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 EKE40891.1 - 0.018 14.5 0.1 4 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EKE40891.1 - 0.019 14.4 0.1 0.062 12.7 0.1 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EKE40891.1 - 0.031 13.7 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EKE40891.1 - 0.038 13.7 0.0 0.083 12.5 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EKE40891.1 - 0.045 13.7 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EKE40891.1 - 0.05 13.0 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EKE40891.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKE40891.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EKE40891.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EKE40891.1 - 0.099 12.3 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA PF00004.24 EKE40891.1 - 0.11 12.7 0.0 0.33 11.1 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L7Ae PF01248.21 EKE40892.1 - 1.7e-22 78.7 0.1 2e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-HIT PF04438.11 EKE40893.1 - 7.1e-11 41.5 13.4 1.4e-10 40.6 9.3 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EKE40893.1 - 0.0017 18.2 13.7 0.004 17.0 9.5 1.7 1 0 0 1 1 1 1 MYND finger YL1_C PF08265.6 EKE40893.1 - 0.015 14.8 0.7 0.025 14.1 0.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PolC_DP2 PF03833.8 EKE40893.1 - 0.77 7.3 9.2 0.2 9.2 4.4 1.4 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 Ecl1 PF12855.2 EKE40893.1 - 3.6 6.9 11.0 13 5.2 7.6 2.0 1 0 0 1 1 1 0 Life-span regulatory factor zf-C2H2_4 PF13894.1 EKE40893.1 - 8.4 6.9 9.9 9.9 6.7 3.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger LuxS PF02664.10 EKE40894.1 - 0.0031 17.0 0.6 0.0035 16.8 0.4 1.2 1 0 0 1 1 1 1 S-Ribosylhomocysteinase (LuxS) AAA_22 PF13401.1 EKE40895.1 - 7.5e-11 42.2 0.0 1.9e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKE40895.1 - 6.6e-10 39.2 0.1 2.1e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE40895.1 - 1.2e-08 35.1 0.0 5.9e-07 29.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EKE40895.1 - 1.8e-05 24.5 2.6 0.00017 21.3 1.8 2.3 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EKE40895.1 - 5e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EKE40895.1 - 0.0001 22.2 0.1 0.00019 21.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EKE40895.1 - 0.00015 20.7 0.6 0.00037 19.4 0.4 2.0 1 1 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.13 EKE40895.1 - 0.0005 19.6 0.1 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EKE40895.1 - 0.00055 20.7 0.1 0.0012 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AFG1_ATPase PF03969.11 EKE40895.1 - 0.0016 17.2 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_18 PF13238.1 EKE40895.1 - 0.0065 16.7 1.0 0.017 15.4 0.7 1.9 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EKE40895.1 - 0.008 15.6 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain NTPase_1 PF03266.10 EKE40895.1 - 0.0082 15.8 1.4 0.36 10.5 0.9 2.8 1 1 0 1 1 1 1 NTPase AAA_33 PF13671.1 EKE40895.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EKE40895.1 - 0.011 14.4 3.5 0.32 9.6 2.4 2.3 1 1 0 1 1 1 0 G-protein alpha subunit DUF1896 PF08989.5 EKE40895.1 - 0.016 15.1 0.7 0.1 12.4 0.0 2.4 3 1 0 3 3 2 0 Domain of unknown function (DUF1896) Miro PF08477.8 EKE40895.1 - 0.023 15.2 0.1 0.062 13.8 0.1 1.7 1 1 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 EKE40895.1 - 0.032 13.6 0.0 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EKE40895.1 - 0.077 13.1 0.1 0.62 10.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.24 EKE40895.1 - 0.097 12.1 0.0 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 EKE40895.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EKE40895.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Copine PF07002.11 EKE40896.1 - 2.8e-46 156.8 0.0 3.7e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EKE40896.1 - 4.7e-13 49.4 0.0 6.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EKE40896.1 - 1.5e-05 25.1 0.0 1.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE40896.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Asn_synthase PF00733.16 EKE40897.1 - 4.1e-29 101.8 0.0 7.6e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EKE40897.1 - 0.016 14.4 0.0 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC YxiJ PF14176.1 EKE40897.1 - 0.052 13.6 6.2 7.4 6.7 3.6 2.8 2 0 0 2 2 2 0 YxiJ-like protein NT-C2 PF10358.4 EKE40898.1 - 6.2e-14 51.6 0.3 6.2e-14 51.6 0.2 2.8 3 1 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EKE40898.1 - 0.01 15.6 0.9 0.01 15.6 0.6 2.0 2 0 0 2 2 2 0 DIL domain DUF1599 PF07659.6 EKE40898.1 - 2.4 8.3 8.1 0.097 12.7 1.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1599) zf-Mss51 PF13824.1 EKE40899.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3189 PF11385.3 EKE40899.1 - 0.16 11.5 2.0 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3189) GFO_IDH_MocA PF01408.17 EKE40900.1 - 3.5e-16 59.7 0.0 7.1e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EKE40900.1 - 0.064 13.1 0.0 0.81 9.6 0.0 2.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HTH_22 PF13309.1 EKE40902.1 - 0.0018 17.9 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 HTH domain Orbi_VP1 PF05788.7 EKE40902.1 - 0.0084 13.3 0.8 0.0089 13.2 0.6 1.0 1 0 0 1 1 1 1 Orbivirus RNA-dependent RNA polymerase (VP1) Leuk-A4-hydro_C PF09127.6 EKE40902.1 - 0.043 13.4 1.1 0.068 12.7 0.3 1.7 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal PCI PF01399.22 EKE40903.1 - 0.0021 18.3 0.1 0.0033 17.7 0.0 1.4 2 0 0 2 2 2 1 PCI domain ThiF PF00899.16 EKE40905.1 - 2.2e-09 37.2 0.8 6e-09 35.8 0.0 2.2 4 0 0 4 4 4 1 ThiF family DUF956 PF06115.6 EKE40905.1 - 0.029 13.9 0.6 5.2 6.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF956) Ank_2 PF12796.2 EKE40906.1 - 5.2e-70 231.8 3.6 4.2e-13 49.4 0.0 7.5 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EKE40906.1 - 3.1e-66 216.0 3.1 1.2e-06 28.0 0.0 15.1 15 0 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 EKE40906.1 - 2.8e-62 206.0 5.3 5.7e-09 36.2 0.0 11.4 7 3 5 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE40906.1 - 1.3e-58 189.0 3.4 0.00017 21.4 0.0 15.4 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.1 EKE40906.1 - 1.8e-58 193.2 6.8 1.2e-10 41.2 0.0 12.7 6 4 7 14 14 14 12 Ankyrin repeats (many copies) SH3_9 PF14604.1 EKE40906.1 - 8.2e-06 25.3 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE40906.1 - 0.0001 21.7 0.1 0.00029 20.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EKE40906.1 - 0.013 14.8 0.1 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 SH3 domain PQQ_2 PF13360.1 EKE40907.1 - 0.023 14.1 0.0 0.065 12.6 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain DUF1664 PF07889.7 EKE40907.1 - 0.023 14.4 27.7 0.11 12.3 6.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DZR PF12773.2 EKE40907.1 - 0.12 12.2 7.5 0.1 12.4 2.5 2.1 1 1 1 2 2 2 0 Double zinc ribbon Aminotran_5 PF00266.14 EKE40908.1 - 8.9e-82 274.7 0.0 1.1e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EKE40908.1 - 2.8e-08 33.2 0.0 3.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EKE40908.1 - 5.9e-08 32.0 0.0 7.1e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EKE40908.1 - 0.00042 19.4 0.1 0.00089 18.4 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EKE40908.1 - 0.0023 16.6 0.1 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein ELM2 PF01448.19 EKE40909.1 - 0.031 14.9 0.0 3.5 8.3 0.1 2.3 2 0 0 2 2 2 0 ELM2 domain MCH PF02289.11 EKE40909.1 - 0.052 12.5 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Cyclohydrolase (MCH) LCAT PF02450.10 EKE40910.1 - 6.8e-32 110.8 0.1 3.1e-30 105.4 0.0 2.1 1 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EKE40910.1 - 0.00029 20.4 0.0 0.0021 17.6 0.0 2.2 2 1 1 3 3 3 1 PGAP1-like protein Lipase_2 PF01674.13 EKE40910.1 - 0.00076 18.8 0.0 0.0019 17.5 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 2) DUF2305 PF10230.4 EKE40910.1 - 0.0099 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EKE40910.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EKE40910.1 - 0.014 14.6 0.0 0.035 13.3 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.7 EKE40910.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EKE40910.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1759 PF03564.10 EKE40911.1 - 0.16 11.7 11.1 2.6 7.8 3.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) TMP_2 PF06791.8 EKE40911.1 - 0.26 10.8 1.6 0.37 10.3 0.2 1.9 2 1 0 2 2 2 0 Prophage tail length tape measure protein H-kinase_dim PF02895.9 EKE40911.1 - 0.97 9.8 4.5 0.38 11.1 0.3 2.4 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Abi_C PF14355.1 EKE40911.1 - 1 9.3 3.2 3.6 7.5 0.2 3.0 3 0 0 3 3 3 0 Abortive infection C-terminus FCH PF00611.18 EKE40911.1 - 4.8 7.4 13.1 6.4 7.0 0.8 3.3 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Myb_DNA-binding PF00249.26 EKE40912.1 - 1.8e-11 43.9 0.2 2.5e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE40912.1 - 0.0025 17.8 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain CD24 PF14984.1 EKE40912.1 - 0.061 13.1 1.6 0.061 13.1 1.1 2.0 2 0 0 2 2 2 0 CD24 protein DUF1474 PF07342.6 EKE40913.1 - 0.07 13.3 0.8 0.15 12.3 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) CH PF00307.26 EKE40914.1 - 7.8e-26 90.2 2.7 8.6e-13 48.2 0.1 3.2 3 1 0 3 3 3 2 Calponin homology (CH) domain Reo_sigmaC PF04582.7 EKE40914.1 - 5.8e-05 22.4 3.9 0.0085 15.3 0.2 2.3 1 1 1 2 2 2 2 Reovirus sigma C capsid protein CAMSAP_CH PF11971.3 EKE40914.1 - 0.00011 21.8 0.2 0.48 10.1 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain AAA_13 PF13166.1 EKE40914.1 - 0.00014 20.4 45.6 0.00014 20.4 31.6 1.7 1 1 0 1 1 1 1 AAA domain IncA PF04156.9 EKE40914.1 - 0.00056 19.5 52.7 0.014 15.0 25.0 3.1 2 1 1 3 3 3 2 IncA protein ATG16 PF08614.6 EKE40914.1 - 0.00058 19.7 17.9 0.00058 19.7 12.4 4.2 2 1 2 5 5 5 2 Autophagy protein 16 (ATG16) MCPsignal PF00015.16 EKE40914.1 - 0.096 12.2 15.6 0.6 9.6 1.4 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 EKE40914.1 - 0.19 11.4 34.9 1.3 8.8 9.0 3.3 1 1 2 3 3 3 0 Laminin Domain II DUF2968 PF11180.3 EKE40914.1 - 0.39 10.0 25.6 0.022 14.1 5.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF1664 PF07889.7 EKE40914.1 - 0.39 10.5 33.6 0.17 11.6 1.0 4.1 2 1 2 4 4 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 EKE40914.1 - 1.1 6.5 45.1 2.5 5.2 13.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 EKE40914.1 - 1.3 9.3 18.0 7.8 6.8 3.3 4.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EKE40914.1 - 2.5 7.2 65.9 2.7 7.1 29.9 3.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 EKE40914.1 - 3.8 6.7 34.1 1.8 7.7 6.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.4 EKE40914.1 - 7.8 4.7 36.7 1.5 7.1 10.4 2.5 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain NosD PF05048.8 EKE40915.1 - 2.3e-30 105.5 30.0 1.7e-12 47.0 2.3 3.1 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 EKE40915.1 - 2.1e-27 95.8 40.0 4.2e-13 49.3 11.4 3.3 1 1 2 3 3 3 3 Right handed beta helix region Pectate_lyase_3 PF12708.2 EKE40915.1 - 6.1e-07 29.7 14.0 0.0003 20.9 0.5 4.5 1 1 3 4 4 4 3 Pectate lyase superfamily protein Pkinase_Tyr PF07714.12 EKE40916.1 - 9.9e-55 185.3 0.0 1.6e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40916.1 - 3.4e-51 173.8 0.0 2.5e-49 167.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DUF4215 PF13948.1 EKE40916.1 - 0.073 13.3 82.6 0.66 10.2 1.5 7.6 2 2 4 6 6 6 0 Domain of unknown function (DUF4215) Kdo PF06293.9 EKE40916.1 - 0.29 10.1 0.0 0.5 9.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BRI3BP PF14965.1 EKE40916.1 - 8.6 5.6 5.9 47 3.2 2.0 2.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 CoaE PF01121.15 EKE40917.1 - 7.2e-37 126.5 0.2 9e-37 126.2 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EKE40917.1 - 1.6e-07 31.7 0.8 4.5e-07 30.2 0.4 1.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EKE40917.1 - 1.6e-07 32.1 0.5 2.4e-07 31.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKE40917.1 - 0.0053 16.6 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EKE40917.1 - 0.012 15.5 0.2 0.025 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain FTA4 PF13093.1 EKE40917.1 - 0.059 12.7 1.0 0.085 12.2 0.7 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Img2 PF05046.9 EKE40917.1 - 0.5 10.6 2.3 0.78 10.0 0.3 2.0 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Pkinase PF00069.20 EKE40919.1 - 6e-70 235.3 0.0 7.8e-70 234.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40919.1 - 5.5e-37 127.2 0.0 7.9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE40919.1 - 6.9e-06 25.2 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE40919.1 - 0.017 14.8 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Spt20 PF12090.3 EKE40919.1 - 0.033 13.5 0.0 0.083 12.2 0.0 1.7 1 1 0 1 1 1 0 Spt20 family R-HINP1I PF11463.3 EKE40919.1 - 0.048 13.0 0.6 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 R.HinP1I restriction endonuclease Radial_spoke PF04712.7 EKE40920.1 - 0.016 14.0 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PH PF00169.24 EKE40921.1 - 7.7e-10 38.9 1.0 1.7e-09 37.8 0.2 1.9 2 0 0 2 2 2 1 PH domain DUF758 PF05527.6 EKE40921.1 - 9e-07 28.6 1.9 1.7e-06 27.8 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH_11 PF15413.1 EKE40921.1 - 0.0029 17.8 2.3 0.0038 17.4 0.5 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EKE40921.1 - 0.0066 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4290 PF14123.1 EKE40921.1 - 0.0072 15.5 1.5 0.015 14.4 0.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4290) NgoMIV_restric PF09015.5 EKE40921.1 - 0.03 13.3 0.1 0.042 12.8 0.1 1.2 1 0 0 1 1 1 0 NgoMIV restriction enzyme Lambda_CIII PF02061.11 EKE40921.1 - 0.22 11.5 0.9 8.4 6.4 0.0 2.6 3 0 0 3 3 3 0 Lambda Phage CIII EAP30 PF04157.11 EKE40922.1 - 3.8e-23 81.8 0.5 4.3e-23 81.6 0.3 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR PF01047.17 EKE40922.1 - 0.0074 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 EKE40922.1 - 0.036 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Penicillinase_R PF03965.11 EKE40922.1 - 0.037 14.1 0.1 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Penicillinase repressor FeoC PF09012.5 EKE40922.1 - 0.07 12.8 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator Apo-CII PF05355.6 EKE40922.1 - 0.094 12.5 0.2 3.6 7.5 0.0 2.4 1 1 1 2 2 2 0 Apolipoprotein C-II PRD PF00874.15 EKE40922.1 - 0.89 9.7 10.3 7.7 6.7 0.2 3.3 2 1 1 3 3 3 0 PRD domain Abhydrolase_5 PF12695.2 EKE40923.1 - 6.5e-19 68.1 0.0 3.3e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE40923.1 - 9.5e-19 68.1 0.0 1.2e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE40923.1 - 8.1e-11 41.9 0.0 1.1e-06 28.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EKE40923.1 - 5.2e-09 35.8 0.0 8.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EKE40923.1 - 1.1e-07 31.3 0.4 0.0033 16.6 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.20 EKE40923.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF676 PF05057.9 EKE40923.1 - 0.001 18.4 0.1 0.0028 16.9 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EKE40923.1 - 0.0015 18.2 0.1 0.0029 17.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 EKE40923.1 - 0.0026 17.0 0.0 2.3 7.4 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.15 EKE40923.1 - 0.004 17.4 0.0 0.0069 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.6 EKE40923.1 - 0.0093 15.6 0.1 0.021 14.5 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 EKE40923.1 - 0.051 12.9 0.5 0.11 11.9 0.3 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 EKE40923.1 - 0.11 11.8 0.0 3.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.15 EKE40923.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Pyr_redox_2 PF07992.9 EKE40924.1 - 6e-08 32.8 0.1 1.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ATP-grasp_5 PF13549.1 EKE40925.1 - 1.6e-79 266.2 0.1 2.2e-79 265.7 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EKE40925.1 - 7.4e-55 184.3 0.2 4.9e-54 181.6 0.1 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EKE40925.1 - 2.9e-20 72.5 0.6 2.6e-19 69.4 0.0 2.4 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.14 EKE40925.1 - 9.8e-14 51.6 0.3 9.8e-14 51.6 0.2 2.5 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.5 EKE40925.1 - 1.8e-05 24.2 0.9 4e-05 23.1 0.6 1.6 1 1 0 1 1 1 1 ATP-grasp domain OKR_DC_1_N PF03709.10 EKE40925.1 - 0.014 15.4 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Got1 PF04178.7 EKE40926.1 - 0.0032 17.5 21.2 0.006 16.6 14.5 1.6 1 1 0 1 1 1 1 Got1/Sft2-like family Alpha-amylase PF00128.19 EKE40927.1 - 9.5e-104 347.1 8.5 1.6e-103 346.4 5.9 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Enolase_C PF00113.17 EKE40928.1 - 1.4e-137 457.5 0.2 1.8e-137 457.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EKE40928.1 - 2.9e-61 205.2 0.0 4.9e-61 204.4 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EKE40928.1 - 0.00013 21.8 0.0 0.00034 20.5 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EKE40928.1 - 0.0013 17.7 0.2 0.0025 16.8 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Pex26 PF07163.7 EKE40928.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein Pkinase_Tyr PF07714.12 EKE40929.1 - 3.4e-59 200.0 0.0 6.4e-59 199.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40929.1 - 4.6e-56 189.8 0.1 1.2e-55 188.4 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EKE40929.1 - 1.9e-21 76.1 7.4 1.2e-09 38.3 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKE40929.1 - 1.4e-20 71.9 0.0 2.5e-05 23.8 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EKE40929.1 - 2.6e-20 72.3 1.5 0.00038 20.8 0.0 5.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE40929.1 - 1.7e-14 52.4 1.2 0.0049 16.9 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EKE40929.1 - 3.4e-14 52.5 0.0 1.5e-05 25.1 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SAM_2 PF07647.12 EKE40929.1 - 0.0048 16.7 0.3 0.013 15.3 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EKE40929.1 - 0.067 13.3 0.3 0.21 11.7 0.2 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AMP-binding PF00501.23 EKE40930.1 - 1.3e-71 241.1 0.0 1.6e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKE40930.1 - 0.0034 18.2 0.0 0.0086 16.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_1 PF00018.23 EKE40930.1 - 0.02 14.2 0.0 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 SH3 domain tRNA_anti-like PF12869.2 EKE40930.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like Spore_III_AF PF09581.5 EKE40931.1 - 0.61 9.9 3.2 1.1 9.1 2.2 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) SCRG1 PF15224.1 EKE40932.1 - 0.06 13.1 1.6 0.1 12.3 0.4 1.9 2 0 0 2 2 2 0 Scrapie-responsive protein 1 CDC73 PF05179.9 EKE40934.1 - 1.2e-11 44.4 3.9 7.3e-11 41.9 2.7 1.9 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RyR PF02026.11 EKE40934.1 - 0.099 12.6 0.4 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 RyR domain DltD_M PF04918.7 EKE40934.1 - 0.18 12.0 1.2 0.3 11.2 0.9 1.3 1 0 0 1 1 1 0 DltD central region Lectin_leg-like PF03388.8 EKE40935.1 - 4.3e-38 130.7 0.5 7e-38 130.0 0.4 1.3 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EKE40935.1 - 1.1e-08 34.7 0.3 1.8e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Legume lectin domain DUF4064 PF13273.1 EKE40936.1 - 3e-05 24.0 0.1 8.9e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF1517 PF07466.6 EKE40936.1 - 0.059 12.3 0.9 0.093 11.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Methyltransf_31 PF13847.1 EKE40937.1 - 1.6e-12 47.2 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE40937.1 - 8.3e-10 39.2 0.0 1.1e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE40937.1 - 8.8e-10 38.6 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKE40937.1 - 1.1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE40937.1 - 1.3e-06 27.8 0.0 1.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EKE40937.1 - 1.6e-06 27.4 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EKE40937.1 - 1.7e-06 28.4 0.0 2.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE40937.1 - 2.2e-06 28.0 0.0 4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EKE40937.1 - 3.1e-06 26.6 0.0 4.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 EKE40937.1 - 4.4e-05 23.2 0.0 5.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EKE40937.1 - 0.00021 20.9 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 EKE40937.1 - 0.001 18.2 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EKE40937.1 - 0.0035 16.4 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 EKE40937.1 - 0.0051 16.1 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EKE40937.1 - 0.019 14.5 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_5 PF01795.14 EKE40937.1 - 0.033 13.4 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_8 PF05148.10 EKE40937.1 - 0.034 13.7 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF633 PF04816.7 EKE40937.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) Methyltransf_15 PF09445.5 EKE40937.1 - 0.046 13.2 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.11 EKE40937.1 - 0.056 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme TehB PF03848.9 EKE40937.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB N6_N4_Mtase PF01555.13 EKE40937.1 - 0.081 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA methylase Met_10 PF02475.11 EKE40937.1 - 0.084 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein AdoMet_MTase PF07757.8 EKE40937.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TLD PF07534.11 EKE40938.1 - 3.8e-08 33.4 2.8 5.8e-08 32.8 1.9 1.3 1 0 0 1 1 1 1 TLD SNAP PF14938.1 EKE40939.1 - 1.5e-16 60.4 5.8 2.5e-16 59.6 4.0 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP NSF PF02071.15 EKE40939.1 - 7.5e-05 22.5 5.7 0.085 13.4 0.4 4.9 5 0 0 5 5 5 2 Aromatic-di-Alanine (AdAR) repeat Metallophos_2 PF12850.2 EKE40940.1 - 1.3e-11 44.5 2.9 2.6e-11 43.5 2.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EKE40940.1 - 8.1e-09 34.9 0.0 3.3e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Metallophos PF00149.23 EKE40940.1 - 1.6e-06 27.7 4.6 1.2e-05 24.8 3.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_E_B PF04042.11 EKE40940.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.23 EKE40941.1 - 3.8e-26 91.7 0.2 7.2e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1411 PF07199.6 EKE40941.1 - 0.21 11.0 2.1 0.38 10.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) PCI PF01399.22 EKE40942.1 - 3.9e-14 52.8 0.9 3.9e-14 52.8 0.6 2.6 2 1 0 2 2 2 1 PCI domain Beta-Casp PF10996.3 EKE40943.1 - 3.9e-27 94.6 0.0 9.8e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 EKE40943.1 - 3.4e-13 49.5 1.4 5.8e-13 48.8 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKE40943.1 - 5.7e-13 48.9 0.0 8.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EKE40943.1 - 4.5e-06 26.3 0.1 1.2e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EKE40943.1 - 9.9e-05 22.1 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_2 PF07719.12 EKE40944.1 - 0.0029 17.3 1.3 0.38 10.7 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PCI PF01399.22 EKE40944.1 - 0.0074 16.5 0.6 0.0074 16.5 0.4 2.7 3 0 0 3 3 3 1 PCI domain Met_gamma_lyase PF06838.6 EKE40944.1 - 0.011 14.1 2.1 0.015 13.5 1.5 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase NB PF04159.8 EKE40944.1 - 0.076 12.7 0.3 0.076 12.7 0.2 2.5 2 0 0 2 2 2 0 NB glycoprotein TPR_11 PF13414.1 EKE40944.1 - 0.11 12.1 0.3 24 4.6 0.1 2.8 3 0 0 3 3 3 0 TPR repeat HMG_box_2 PF09011.5 EKE40947.1 - 2.5e-07 30.9 0.5 2.5e-07 30.9 0.3 2.4 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.14 EKE40947.1 - 3.3e-06 27.2 0.5 3.3e-06 27.2 0.4 2.4 2 2 0 2 2 2 1 HMG (high mobility group) box DUF2507 PF10702.4 EKE40947.1 - 0.022 14.4 0.8 0.046 13.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) Pkinase_Tyr PF07714.12 EKE40948.1 - 2.5e-38 131.6 0.0 7.2e-38 130.1 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40948.1 - 9.7e-33 113.4 0.1 2.4e-32 112.1 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.1 EKE40948.1 - 1.1e-17 63.5 32.7 3e-07 30.0 2.6 5.4 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EKE40948.1 - 3.7e-15 55.1 41.2 1.9e-05 24.1 0.5 7.4 4 3 1 7 7 7 6 Leucine Rich repeats (2 copies) Myotub-related PF06602.9 EKE40948.1 - 1.2e-14 53.8 1.2 1.2e-14 53.8 0.8 2.1 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain LRR_1 PF00560.28 EKE40948.1 - 3.5e-06 26.2 27.1 0.43 10.8 0.4 9.5 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 EKE40948.1 - 0.00026 20.6 25.0 3.5 8.2 0.0 9.1 9 1 0 9 9 9 2 Leucine rich repeat LRR_6 PF13516.1 EKE40948.1 - 1 9.6 25.5 16 5.9 0.1 8.5 8 0 0 8 8 8 0 Leucine Rich repeat Ist1 PF03398.9 EKE40949.1 - 4.9e-15 55.3 2.0 7.3e-15 54.7 1.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF605 PF04652.11 EKE40949.1 - 0.014 14.8 21.8 0.018 14.4 15.1 1.1 1 0 0 1 1 1 0 Vta1 like SART-1 PF03343.8 EKE40950.1 - 5.6e-13 48.1 0.0 6.4e-11 41.3 0.1 2.1 1 1 1 2 2 2 2 SART-1 family WD40 PF00400.27 EKE40951.1 - 1.7e-06 27.6 4.1 0.69 9.8 0.0 5.2 4 2 1 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EKE40951.1 - 0.00024 21.2 0.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 2 PQQ-like domain Glyco_hydro_114 PF03537.8 EKE40951.1 - 0.028 14.2 0.1 4.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 RNA_ligase PF09414.5 EKE40951.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA ligase MIG-14_Wnt-bd PF06664.7 EKE40952.1 - 1.5e-06 27.2 10.9 1.8e-06 27.0 7.6 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion COX4_pro PF03626.9 EKE40952.1 - 0.015 15.3 5.9 0.12 12.4 4.0 2.2 1 1 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV DUF3816 PF12822.2 EKE40952.1 - 0.83 9.5 13.1 1.1 9.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Ribosomal_S17e PF00833.13 EKE40954.1 - 9.8e-56 186.7 1.1 1.1e-55 186.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal S17 RRM_5 PF13893.1 EKE40955.1 - 4.7e-24 83.9 1.4 5.6e-15 54.9 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE40955.1 - 1.7e-21 75.6 3.3 5.3e-16 58.0 0.4 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE40955.1 - 1.6e-16 60.0 0.4 6.1e-11 42.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 EKE40956.1 - 4.5e-28 97.1 0.7 8.3e-28 96.3 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EKE40956.1 - 6.6e-05 23.0 0.1 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Kinetochore component CENP-S CENP-T PF15511.1 EKE40956.1 - 0.059 12.6 1.3 0.079 12.2 0.9 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EKE40956.1 - 0.091 12.8 1.9 0.097 12.7 0.1 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UL2 PF08196.6 EKE40957.1 - 0.4 10.4 4.5 0.28 10.9 0.1 2.7 2 0 0 2 2 2 0 UL2 protein zf-rbx1 PF12678.2 EKE40958.1 - 1.3e-25 89.2 18.2 1.6e-25 88.9 12.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EKE40958.1 - 8.2e-25 86.4 16.2 9.3e-25 86.3 11.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EKE40958.1 - 3.2e-06 26.8 30.8 3.7e-05 23.4 21.4 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EKE40958.1 - 0.00053 19.6 13.4 0.0012 18.4 2.6 2.9 2 1 1 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.1 EKE40958.1 - 0.0012 18.5 18.7 0.0012 18.5 13.0 2.5 1 1 1 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKE40958.1 - 0.0021 17.6 23.8 0.066 12.8 16.6 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE40958.1 - 0.0035 17.1 3.5 0.0035 17.1 2.4 3.0 2 2 1 3 3 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EKE40958.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.1 EKE40958.1 - 0.016 15.1 26.4 0.23 11.5 18.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE40958.1 - 0.26 10.9 28.5 3 7.5 19.7 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EKE40958.1 - 1.8 7.7 7.7 1.8 7.6 5.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 EKE40958.1 - 2.1 7.9 14.6 4 7.0 10.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Steroid_dh PF02544.11 EKE40959.1 - 1.1e-08 34.9 6.2 2.2e-08 34.0 4.3 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EKE40959.1 - 1.3e-07 30.9 0.1 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE40959.1 - 0.048 13.3 0.2 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Transp_Tc5_C PF04236.10 EKE40959.1 - 0.17 12.1 0.4 0.17 12.1 0.3 2.7 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain DENN PF02141.16 EKE40960.1 - 6.6e-20 71.6 1.2 2e-19 70.0 0.8 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EKE40960.1 - 0.001 19.1 12.4 0.0032 17.5 8.6 1.9 1 0 0 1 1 1 1 dDENN domain LIM PF00412.17 EKE40960.1 - 0.04 13.9 5.4 0.11 12.5 3.7 1.9 1 0 0 1 1 1 0 LIM domain DUF896 PF05979.7 EKE40960.1 - 0.15 11.7 1.6 0.37 10.4 1.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Prok-RING_1 PF14446.1 EKE40960.1 - 3.5 7.4 7.4 3.1 7.6 4.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Peptidase_M20 PF01546.23 EKE40961.1 - 1.3e-20 73.7 0.3 1.8e-20 73.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EKE40961.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 EKE40961.1 - 0.0027 17.4 2.2 0.0036 17.0 0.8 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Pro_3_hydrox_C PF05373.6 EKE40961.1 - 0.15 12.1 0.3 19 5.3 0.0 2.5 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal tRNA_int_endo PF01974.12 EKE40962.1 - 6.9e-20 70.6 0.2 1.1e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RasGAP PF00616.14 EKE40963.1 - 3.7e-17 62.6 5.9 9.2e-08 31.9 0.0 3.2 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase bZIP_1 PF00170.16 EKE40963.1 - 0.027 14.4 0.2 0.089 12.7 0.1 1.9 1 0 0 1 1 1 0 bZIP transcription factor DUF2066 PF09839.4 EKE40963.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) ACCA PF03255.9 EKE40964.1 - 4.8 6.7 6.7 12 5.4 0.9 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ANF_receptor PF01094.23 EKE40965.1 - 1.1e-05 24.3 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EKE40965.1 - 0.018 14.4 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Maelstrom PF13017.1 EKE40965.1 - 0.19 11.2 1.3 0.48 9.8 0.9 1.6 1 1 0 1 1 1 0 piRNA pathway germ-plasm component Ras PF00071.17 EKE40967.1 - 2.9e-17 62.5 0.1 3.8e-17 62.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40967.1 - 0.0014 19.0 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FH2 PF02181.18 EKE40969.1 - 1.1e-21 77.1 5.9 1.1e-21 77.1 4.1 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Coatomer_WDAD PF04053.9 EKE40970.1 - 1.4e-136 455.8 3.2 1.4e-136 455.8 2.2 2.5 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 EKE40970.1 - 1.2e-47 158.1 10.7 5e-10 38.8 0.2 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE40970.1 - 1.4e-07 31.2 0.9 1.6 8.5 0.0 4.7 3 1 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EKE40970.1 - 7.2e-05 21.7 1.8 0.00087 18.1 0.3 3.1 1 1 1 2 2 2 1 Nup133 N terminal like Clathrin PF00637.15 EKE40970.1 - 0.0072 15.9 4.3 0.06 12.9 0.3 2.6 1 1 2 3 3 3 3 Region in Clathrin and VPS Nup160 PF11715.3 EKE40970.1 - 0.08 11.0 0.5 3.4 5.6 0.0 2.9 2 2 1 3 3 3 0 Nucleoporin Nup120/160 Metallophos PF00149.23 EKE40972.1 - 2e-30 105.6 0.9 2.6e-30 105.3 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE40972.1 - 7.6e-05 22.5 0.0 8.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4247 PF14042.1 EKE40972.1 - 0.096 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) Rhodanese PF00581.15 EKE40973.1 - 2.9e-09 37.2 0.0 7.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain RabGAP-TBC PF00566.13 EKE40973.1 - 1.5e-05 24.6 5.6 4.8e-05 22.9 4.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AAA PF00004.24 EKE40975.1 - 1.5e-44 151.3 0.0 3.5e-44 150.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKE40975.1 - 1.3e-08 34.7 0.1 4.7e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKE40975.1 - 3.1e-08 33.6 0.0 9.8e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EKE40975.1 - 7.4e-07 29.3 0.0 2.2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKE40975.1 - 2.6e-06 27.5 0.9 0.00037 20.6 0.3 2.8 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EKE40975.1 - 0.00028 20.5 0.0 0.0007 19.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EKE40975.1 - 0.00042 20.3 0.0 0.00096 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EKE40975.1 - 0.00047 19.1 0.0 0.00088 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EKE40975.1 - 0.00052 19.9 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EKE40975.1 - 0.00055 19.0 0.0 0.0015 17.6 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EKE40975.1 - 0.00062 19.2 0.0 0.0018 17.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EKE40975.1 - 0.0007 19.0 3.7 0.0063 15.9 0.1 2.5 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EKE40975.1 - 0.0011 19.7 0.1 0.0042 17.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain NACHT PF05729.7 EKE40975.1 - 0.0017 18.0 0.1 0.075 12.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.8 EKE40975.1 - 0.0022 16.7 0.0 0.0032 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EKE40975.1 - 0.0025 17.0 0.0 0.0057 15.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EKE40975.1 - 0.0026 17.3 0.0 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE40975.1 - 0.003 17.8 0.0 0.0081 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKE40975.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EKE40975.1 - 0.0069 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EKE40975.1 - 0.0099 15.3 0.0 0.24 10.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EKE40975.1 - 0.012 15.2 0.1 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EKE40975.1 - 0.02 14.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 EKE40975.1 - 0.022 14.3 0.0 0.048 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKE40975.1 - 0.028 14.3 0.2 0.067 13.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EKE40975.1 - 0.028 14.0 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EKE40975.1 - 0.028 14.7 0.4 0.84 9.9 0.0 2.9 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 EKE40975.1 - 0.045 12.6 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EKE40975.1 - 0.048 13.3 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EKE40975.1 - 0.059 12.2 0.0 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EKE40975.1 - 0.089 11.8 1.8 1 8.4 0.0 2.5 2 1 1 3 3 3 0 KaiC AAA_10 PF12846.2 EKE40975.1 - 0.095 12.1 0.1 0.36 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA-like domain WH2 PF02205.15 EKE40976.1 - 1.5e-10 40.2 1.9 6.7e-10 38.2 1.1 2.2 2 0 0 2 2 2 1 WH2 motif His_Phos_2 PF00328.17 EKE40976.1 - 0.0082 15.5 0.7 0.0094 15.3 0.5 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Laminin_II PF06009.7 EKE40976.1 - 0.014 15.1 1.9 0.014 15.1 1.3 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 EKE40976.1 - 0.015 15.0 16.5 0.2 11.4 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1154 PF06631.6 EKE40976.1 - 0.14 11.8 4.2 0.37 10.4 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1154) Myosin_tail_1 PF01576.14 EKE40976.1 - 0.18 9.4 15.8 1.5 6.4 10.8 1.9 1 1 0 1 1 1 0 Myosin tail Spc7 PF08317.6 EKE40976.1 - 0.2 10.2 18.8 0.32 9.6 12.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein FliD_N PF02465.13 EKE40976.1 - 0.23 11.8 6.4 3.5 8.0 0.5 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus WEMBL PF05701.6 EKE40976.1 - 0.23 9.8 13.6 0.039 12.4 1.3 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light FlaF PF07309.6 EKE40976.1 - 0.24 11.2 5.8 0.59 10.0 0.5 2.4 2 1 0 2 2 2 0 Flagellar protein FlaF Cauli_AT PF03233.8 EKE40976.1 - 0.49 10.0 19.2 2.2 7.9 5.3 2.4 1 1 1 2 2 2 0 Aphid transmission protein Reo_sigmaC PF04582.7 EKE40976.1 - 0.5 9.4 6.4 0.29 10.2 0.3 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EKE40976.1 - 0.68 9.6 12.7 1.6 8.4 1.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BPL_N PF09825.4 EKE40976.1 - 0.92 8.2 6.7 0.85 8.3 3.9 1.4 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal DUF745 PF05335.8 EKE40976.1 - 0.92 8.9 10.0 0.85 9.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) POX PF07526.6 EKE40976.1 - 1.2 9.4 6.2 2.4 8.3 4.3 1.6 1 0 0 1 1 1 0 Associated with HOX Glyco_hydro_67N PF03648.9 EKE40976.1 - 1.2 9.1 3.8 6.4 6.8 0.7 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus MCPsignal PF00015.16 EKE40976.1 - 1.5 8.3 15.4 1.1 8.8 0.6 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.6 EKE40976.1 - 1.7 9.1 8.4 1.9 8.9 3.6 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4446 PF14584.1 EKE40976.1 - 1.7 8.4 10.8 7.9 6.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Fib_alpha PF08702.5 EKE40976.1 - 1.8 8.6 19.2 1.6 8.8 1.7 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1319 PF07028.6 EKE40976.1 - 2.7 8.2 18.8 16 5.6 9.5 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF1319) DUF2547 PF10818.3 EKE40976.1 - 3 8.5 7.0 1 10.0 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) DUF1515 PF07439.6 EKE40976.1 - 3.1 7.6 5.3 14 5.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) APG17 PF04108.7 EKE40976.1 - 5.2 5.7 15.1 0.64 8.7 1.4 2.3 1 1 1 2 2 2 0 Autophagy protein Apg17 Sec8_exocyst PF04048.9 EKE40976.1 - 8.8 5.9 16.9 0.4 10.2 1.4 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.14 EKE40976.1 - 9.3 3.9 15.7 2.9 5.6 2.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 EKE40977.1 - 4.9e-21 75.0 0.1 2.5e-20 72.7 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE40977.1 - 7.1e-19 67.8 0.0 1.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Isy1 PF06246.7 EKE40977.1 - 0.016 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Isy1-like splicing family DUF912 PF06024.7 EKE40977.1 - 0.045 13.8 3.0 0.074 13.1 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Orthoreo_P10 PF07204.6 EKE40977.1 - 1.6 8.4 6.1 0.16 11.6 0.8 1.9 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 FNIP PF05725.7 EKE40978.1 - 0.15 12.0 25.3 2.8 7.9 3.1 6.2 3 1 2 5 5 5 0 FNIP Repeat Seryl_tRNA_N PF02403.17 EKE40979.1 - 0.018 15.0 19.9 0.018 15.0 13.8 3.7 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 EKE40979.1 - 0.07 11.5 40.4 0.091 11.2 28.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EKE40979.1 - 0.096 10.0 39.5 0.15 9.3 27.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EKE40979.1 - 0.27 10.1 43.8 0.31 9.9 8.5 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EKE40979.1 - 0.34 10.8 52.0 1.4 8.7 20.2 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF869 PF05911.6 EKE40979.1 - 0.49 8.5 45.0 0.065 11.4 7.0 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 EKE40979.1 - 1.6 8.1 47.0 1.8 7.9 9.0 2.6 1 1 1 2 2 2 0 Intermediate filament protein Allexi_40kDa PF05549.6 EKE40979.1 - 2.1 7.5 24.8 1.5 8.0 5.3 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein ERM PF00769.14 EKE40979.1 - 6.3 6.2 53.2 3.4 7.1 23.2 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FlaC_arch PF05377.6 EKE40979.1 - 7.3 6.5 26.6 0.097 12.5 0.7 4.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.6 EKE40979.1 - 8.1 6.3 17.2 2.1 8.1 1.4 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) GST_C_3 PF14497.1 EKE40979.1 - 8.2 6.9 6.1 13 6.3 0.1 2.6 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Reo_sigmaC PF04582.7 EKE40979.1 - 9.9 5.2 11.7 7.1 5.7 1.9 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DNA_pol_A_exo1 PF01612.15 EKE40980.1 - 0.00029 20.3 0.9 0.00077 18.9 0.3 2.0 2 0 0 2 2 2 1 3'-5' exonuclease HRDC PF00570.18 EKE40980.1 - 0.00069 19.2 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain tRNA-synt_1c PF00749.16 EKE40981.1 - 3.9e-90 301.7 0.0 5.2e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EKE40981.1 - 3.2e-39 134.3 0.1 6.7e-39 133.3 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Isy1 PF06246.7 EKE40983.1 - 0.4 10.0 5.2 0.51 9.7 3.6 1.0 1 0 0 1 1 1 0 Isy1-like splicing family HABP4_PAI-RBP1 PF04774.10 EKE40983.1 - 0.5 10.8 5.5 0.64 10.5 3.8 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Ras PF00071.17 EKE40984.1 - 7.7e-43 145.6 0.3 8.7e-43 145.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE40984.1 - 2.6e-16 60.1 0.0 3.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE40984.1 - 2.3e-09 36.7 0.0 2.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE40984.1 - 3.3e-07 29.6 0.0 3.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE40984.1 - 0.0059 16.5 0.0 0.0094 15.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE40984.1 - 0.0074 16.4 0.2 0.035 14.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EKE40984.1 - 0.0081 15.3 0.0 0.0094 15.1 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DivIC PF04977.10 EKE40985.1 - 0.061 12.8 0.5 0.061 12.8 0.3 2.4 2 1 0 2 2 2 0 Septum formation initiator Fe-S_assembly PF04384.8 EKE40985.1 - 0.07 13.4 2.4 0.29 11.5 0.1 2.9 3 0 0 3 3 3 0 Iron-sulphur cluster assembly Ribosomal_S7 PF00177.16 EKE40985.1 - 0.074 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Osmo_CC PF08946.5 EKE40985.1 - 0.71 9.9 4.3 5.3 7.1 1.4 2.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Syntaxin PF00804.20 EKE40985.1 - 1.4 9.0 14.3 40 4.4 0.2 2.5 1 1 1 2 2 2 0 Syntaxin DUF948 PF06103.6 EKE40985.1 - 1.9 8.3 10.0 8.9 6.2 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 EKE40985.1 - 2.6 8.2 11.4 5.4 7.2 0.5 2.9 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EKE40985.1 - 3.3 7.4 8.6 3.2 7.5 2.3 2.2 1 1 1 2 2 2 0 Laminin Domain II PhoU_div PF01865.11 EKE40985.1 - 3.4 6.7 8.8 1.7 7.7 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF47 IncA PF04156.9 EKE40985.1 - 3.4 7.2 9.2 1.2 8.7 2.6 2.0 1 1 1 2 2 2 0 IncA protein NPV_P10 PF05531.7 EKE40985.1 - 4.7 7.5 7.6 9 6.6 1.1 2.9 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4404 PF14357.1 EKE40985.1 - 5.2 7.5 8.9 0.93 9.9 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF4557 PF15101.1 EKE40986.1 - 0.95 9.2 10.0 1.5 8.5 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CT47 PF15623.1 EKE40986.1 - 9.4 5.8 25.9 13 5.4 18.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF4215 PF13948.1 EKE40987.1 - 0.00013 22.1 19.6 0.00013 22.1 13.6 4.0 2 2 0 2 2 2 1 Domain of unknown function (DUF4215) TIG PF01833.19 EKE40988.1 - 2.2e-05 24.3 5.9 0.0074 16.2 0.0 2.7 2 0 0 2 2 2 2 IPT/TIG domain FYVE PF01363.16 EKE40988.1 - 0.068 13.0 8.5 0.19 11.6 5.9 1.7 1 0 0 1 1 1 0 FYVE zinc finger RVT_3 PF13456.1 EKE40989.1 - 0.0013 18.4 0.8 2.2 8.1 0.1 2.8 3 0 0 3 3 3 2 Reverse transcriptase-like MTBP_mid PF14919.1 EKE40989.1 - 0.015 13.9 10.8 0.021 13.5 7.5 1.1 1 0 0 1 1 1 0 MDM2-binding Pkinase_Tyr PF07714.12 EKE40990.1 - 1.8e-32 112.4 0.0 3.2e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE40990.1 - 2.9e-22 79.0 0.2 5.3e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain YcbB PF08664.5 EKE40991.1 - 0.018 14.8 1.2 0.028 14.1 0.7 1.5 1 1 0 1 1 1 0 YcbB domain DUF2414 PF10309.4 EKE40991.1 - 0.063 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) CwfJ_C_1 PF04677.10 EKE40992.1 - 5.2e-22 77.7 2.5 6.9e-22 77.3 0.6 2.1 1 1 1 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EKE40992.1 - 1.4e-07 31.9 0.0 5.9e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CPDase PF07823.6 EKE40992.1 - 0.022 14.2 0.5 0.23 10.9 0.1 2.4 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein Flavodoxin_2 PF02525.12 EKE40993.1 - 1.6e-19 70.2 0.0 2e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EKE40993.1 - 1.5e-17 63.5 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EKE40993.1 - 9.6e-05 21.7 0.5 0.00071 18.9 0.3 2.1 1 1 0 1 1 1 1 Flavodoxin DUF3689 PF12463.3 EKE40995.1 - 1.7e-72 243.7 10.3 7.3e-72 241.7 5.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3689) MA3 PF02847.12 EKE40995.1 - 0.016 14.9 1.4 0.16 11.6 0.0 3.0 3 0 0 3 3 3 0 MA3 domain MIG-14_Wnt-bd PF06664.7 EKE40996.1 - 8.5e-39 133.1 46.0 8.5e-39 133.1 31.9 2.0 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF3103 PF11301.3 EKE40996.1 - 0.076 11.6 0.9 0.18 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3103) Herpes_UL45 PF05473.7 EKE40996.1 - 1.8 7.9 6.6 1.8 7.9 0.2 2.6 2 0 0 2 2 2 0 UL45 protein SH3_9 PF14604.1 EKE40997.1 - 7.5e-13 47.8 1.5 2.4e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EKE40997.1 - 1.2e-11 43.8 0.0 1.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKE40997.1 - 4e-10 38.9 0.1 9.3e-10 37.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EKE40997.1 - 4.2e-10 39.5 7.0 5.8e-10 39.0 4.9 1.2 1 0 0 1 1 1 1 BAR domain DUF342 PF03961.8 EKE40997.1 - 1.4 7.2 4.7 1.7 7.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TPR_11 PF13414.1 EKE40998.1 - 1.2e-37 127.3 32.2 4.2e-08 32.7 0.5 9.8 5 3 4 11 11 11 8 TPR repeat TPR_2 PF07719.12 EKE40998.1 - 4.6e-35 116.6 20.8 3.1e-06 26.6 0.1 14.7 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_1 PF00515.23 EKE40998.1 - 7.7e-30 101.2 30.3 7.4e-07 28.5 0.1 13.4 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_12 PF13424.1 EKE40998.1 - 2.2e-27 94.8 16.2 6.6e-07 29.1 0.0 9.5 8 3 1 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EKE40998.1 - 9e-27 93.2 8.0 5.9e-06 26.5 0.1 9.9 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKE40998.1 - 5.1e-22 77.9 0.0 0.0002 21.9 0.0 8.8 8 2 3 11 11 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE40998.1 - 2.3e-21 73.9 32.7 0.0015 18.1 0.0 13.4 13 2 2 15 15 12 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKE40998.1 - 4.9e-19 67.1 0.1 0.82 10.4 0.0 10.2 6 3 4 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 EKE40998.1 - 1.4e-16 60.3 33.6 7.4e-06 26.0 0.1 7.9 5 3 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKE40998.1 - 1.1e-15 56.8 7.2 0.066 13.7 0.0 11.1 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKE40998.1 - 4.7e-13 48.2 18.1 0.19 11.9 0.0 12.4 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKE40998.1 - 2.4e-06 26.9 14.7 0.26 11.1 0.1 8.8 13 1 0 13 13 9 2 Tetratricopeptide repeat Coatomer_E PF04733.9 EKE40998.1 - 7.8e-06 25.2 11.4 0.00077 18.7 1.1 5.0 4 2 0 4 4 4 2 Coatomer epsilon subunit DUF3808 PF10300.4 EKE40998.1 - 0.00016 20.3 6.6 0.00016 20.3 4.5 4.0 2 2 2 4 4 3 1 Protein of unknown function (DUF3808) BTAD PF03704.12 EKE40998.1 - 0.0016 18.7 0.1 0.047 13.9 0.2 2.9 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 EKE40998.1 - 0.0016 18.2 6.4 0.1 12.5 0.2 6.1 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EKE40998.1 - 0.0036 17.1 0.1 1.9 8.4 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.1 EKE40998.1 - 0.0046 16.8 0.5 0.26 11.3 0.0 3.8 4 0 0 4 4 3 1 PPR repeat family PPR_1 PF12854.2 EKE40998.1 - 0.021 14.2 0.0 0.085 12.3 0.0 2.1 1 0 0 1 1 1 0 PPR repeat PPR PF01535.15 EKE40998.1 - 0.035 14.0 2.5 3.2 7.9 0.0 4.9 5 0 0 5 5 5 0 PPR repeat Dus PF01207.12 EKE40999.1 - 5.9e-35 120.5 0.0 8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Nsp1 PF11501.3 EKE40999.1 - 0.0036 17.1 0.0 1.6 8.6 0.0 2.8 3 0 0 3 3 3 2 Non structural protein Nsp1 Histone PF00125.19 EKE41000.1 - 2.8e-14 52.9 0.4 3.9e-14 52.5 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EKE41000.1 - 3.8e-06 26.7 0.1 5.9e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EKE41000.1 - 4.6e-05 23.3 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EKE41000.1 - 0.00015 21.8 0.3 0.0002 21.4 0.2 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EKE41000.1 - 0.00048 19.5 0.0 0.00049 19.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EKE41000.1 - 0.0048 16.6 0.0 0.0066 16.1 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EKE41000.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Vps26 PF03643.10 EKE41001.1 - 5.3e-92 307.4 6.5 6.3e-92 307.2 4.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EKE41001.1 - 7.1e-06 25.8 1.9 8.6e-05 22.3 0.5 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Synaptobrevin PF00957.16 EKE41002.1 - 8.4e-05 22.1 0.6 8.4e-05 22.1 0.4 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF912 PF06024.7 EKE41002.1 - 0.025 14.6 0.1 0.026 14.5 0.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sad1_UNC PF07738.8 EKE41003.1 - 1.5e-08 34.4 2.3 3.1e-08 33.4 0.1 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal DUF2439 PF10382.4 EKE41003.1 - 1.9 8.7 9.4 0.34 11.1 0.3 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2439) DUF1765 PF08578.5 EKE41004.1 - 2.1e-09 37.4 8.5 4.2e-09 36.5 5.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) GN3L_Grn1 PF08701.6 EKE41004.1 - 0.071 13.0 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 GNL3L/Grn1 putative GTPase RasGAP PF00616.14 EKE41005.1 - 1.7e-26 93.1 8.4 5.3e-26 91.5 5.8 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.1 EKE41005.1 - 3.2e-06 26.6 13.4 0.4 10.8 0.0 8.9 8 1 1 9 9 9 1 Leucine Rich repeat LRR_4 PF12799.2 EKE41005.1 - 0.00013 21.5 4.3 2.4 7.8 0.6 5.4 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EKE41005.1 - 0.0011 18.8 0.2 67 4.3 0.0 6.3 7 0 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 EKE41005.1 - 0.012 15.4 9.7 41 4.7 0.1 7.2 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.1 EKE41005.1 - 0.037 13.7 10.1 18 5.1 0.1 5.5 5 1 1 6 6 6 0 Leucine rich repeat DSBA PF01323.15 EKE41006.1 - 7.6e-19 68.0 0.0 2.9e-18 66.1 0.0 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EKE41006.1 - 1.8e-06 28.1 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EKE41006.1 - 2e-06 27.8 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_5 PF13743.1 EKE41006.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin B3_4 PF03483.12 EKE41007.1 - 5.6e-20 71.5 0.0 9.1e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EKE41007.1 - 1.5e-17 63.1 0.0 3.9e-15 55.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain Pkinase PF00069.20 EKE41008.1 - 5.6e-57 192.8 0.0 5.6e-57 192.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41008.1 - 6.1e-24 84.4 0.1 5.3e-21 74.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Mitofilin PF09731.4 EKE41008.1 - 0.0029 16.3 8.7 0.11 11.0 7.4 1.9 2 0 0 2 2 2 1 Mitochondrial inner membrane protein Choline_kinase PF01633.15 EKE41008.1 - 0.0069 15.9 0.1 0.0069 15.9 0.1 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKE41008.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MRP-S26 PF14943.1 EKE41008.1 - 1.9 8.0 17.7 14 5.1 11.5 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF3987 PF13148.1 EKE41008.1 - 2.1 6.8 8.6 3 6.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NARP1 PF12569.3 EKE41008.1 - 2.8 6.6 12.4 4.2 5.9 8.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vps52 PF04129.7 EKE41009.1 - 5e-15 55.0 37.3 8.5e-15 54.2 25.8 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF1313 PF07011.6 EKE41009.1 - 0.18 11.5 6.9 0.034 13.8 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1313) 3H PF02829.9 EKE41009.1 - 0.27 11.2 6.0 3.3 7.8 0.2 3.7 3 0 0 3 3 3 0 3H domain Gp-FAR-1 PF05823.7 EKE41009.1 - 0.93 9.4 12.7 0.047 13.6 1.4 3.6 3 2 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Med4 PF10018.4 EKE41009.1 - 2.4 7.5 5.6 6.8 6.0 1.7 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Ras PF00071.17 EKE41010.1 - 4e-09 36.0 0.2 8.7e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Ras family WD40 PF00400.27 EKE41011.1 - 2.6e-35 119.0 11.3 1.9e-05 24.3 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EKE41011.1 - 1.5e-05 23.3 0.0 0.38 8.8 0.0 4.1 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EKE41011.1 - 0.0027 16.8 0.3 0.042 12.9 0.0 2.7 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EKE41011.1 - 0.0053 16.2 0.0 0.014 14.8 0.0 1.8 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.16 EKE41011.1 - 0.16 11.5 0.7 43 3.9 0.0 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat EMP24_GP25L PF01105.19 EKE41012.1 - 1.5e-34 119.3 2.3 1.7e-34 119.1 1.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD VanZ PF04892.7 EKE41012.1 - 0.13 12.2 0.1 0.13 12.2 0.1 1.6 2 0 0 2 2 2 0 VanZ like family Thioredoxin PF00085.15 EKE41013.1 - 1.1e-07 31.4 0.1 1.5e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DUF1033 PF06279.6 EKE41013.1 - 0.011 15.5 1.5 0.014 15.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Peptidase_C8 PF03569.8 EKE41013.1 - 0.015 14.6 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C8 Ribosomal_S2 PF00318.15 EKE41014.1 - 6.2e-39 133.4 0.2 2.6e-19 69.2 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Adaptin_N PF01602.15 EKE41015.1 - 4.4e-47 160.5 21.9 5e-47 160.4 15.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EKE41015.1 - 1.1e-07 32.0 0.0 0.001 19.3 0.0 2.5 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 EKE41015.1 - 0.00045 20.0 0.3 0.72 10.0 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat WD40 PF00400.27 EKE41016.1 - 3.6e-14 51.9 3.9 1.8e-07 30.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat KSHV_K1 PF11049.3 EKE41016.1 - 0.098 12.6 1.6 1.8 8.6 0.4 2.8 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus MATH PF00917.21 EKE41016.1 - 0.15 12.2 5.4 0.085 13.1 1.6 2.1 2 0 0 2 2 2 0 MATH domain PEHE PF15275.1 EKE41018.1 - 0.00038 20.8 0.2 0.00038 20.8 0.1 2.3 2 0 0 2 2 2 1 PEHE domain YfhO PF09586.5 EKE41018.1 - 4.9 5.0 7.6 6.6 4.6 5.3 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pkinase_Tyr PF07714.12 EKE41019.1 - 8.6e-36 123.3 0.0 2.1e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41019.1 - 1.8e-32 112.5 0.0 4.1e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 EKE41019.1 - 8e-11 41.3 31.8 0.0012 18.4 0.8 6.9 3 1 2 6 6 6 4 Leucine Rich repeats (2 copies) Myotub-related PF06602.9 EKE41019.1 - 4.8e-10 38.7 1.0 1.1e-09 37.5 0.7 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain LRR_7 PF13504.1 EKE41019.1 - 7.7e-05 22.2 20.0 0.069 13.3 0.3 9.1 8 1 1 9 9 9 1 Leucine rich repeat GRAM PF02893.15 EKE41019.1 - 0.0083 15.6 0.3 0.0083 15.6 0.2 2.9 3 0 0 3 3 3 1 GRAM domain LRR_1 PF00560.28 EKE41019.1 - 0.091 12.8 34.8 2.1 8.6 0.0 9.8 9 0 0 9 9 9 0 Leucine Rich Repeat MMPL PF03176.10 EKE41020.1 - 7.7e-68 228.6 8.1 5.7e-36 123.8 0.0 2.2 2 0 0 2 2 2 2 MMPL family DUF3784 PF12650.2 EKE41020.1 - 0.017 15.0 1.6 0.017 15.0 1.1 5.9 6 1 0 6 6 6 0 Domain of unknown function (DUF3784) NARP1 PF12569.3 EKE41021.1 - 2.9e-23 82.4 20.8 2.9e-23 82.4 14.4 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EKE41021.1 - 2.1e-17 63.2 10.8 0.0025 18.0 0.4 6.6 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 EKE41021.1 - 2.4e-09 36.4 24.4 0.13 12.2 0.0 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41021.1 - 2.9e-09 37.3 0.2 0.43 11.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKE41021.1 - 1.4e-08 34.5 9.6 0.16 11.9 0.1 6.5 5 2 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EKE41021.1 - 6.2e-08 32.6 26.6 0.0062 16.6 1.7 5.9 3 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EKE41021.1 - 4.7e-07 29.8 0.0 16 6.4 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKE41021.1 - 2.7e-06 26.9 22.4 0.21 11.2 0.6 6.7 5 3 2 7 7 7 3 TPR repeat TPR_1 PF00515.23 EKE41021.1 - 4e-06 26.2 26.2 0.066 12.8 0.8 7.9 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41021.1 - 0.00012 21.6 34.8 0.11 12.3 0.8 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EKE41021.1 - 0.00079 19.7 11.4 1.4 9.5 0.2 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat ATP13 PF12921.2 EKE41021.1 - 0.0015 17.8 7.3 1 8.7 0.1 4.9 4 1 0 4 4 4 1 Mitochondrial ATPase expression TPR_9 PF13371.1 EKE41021.1 - 0.0052 16.5 0.1 1.3 8.9 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKE41021.1 - 0.02 14.6 8.2 13 5.9 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat 3H PF02829.9 EKE41021.1 - 0.11 12.5 2.8 8.7 6.4 0.1 3.6 3 1 0 3 3 3 0 3H domain POR PF01558.13 EKE41021.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase TPR_17 PF13431.1 EKE41021.1 - 0.16 12.2 9.2 0.27 11.5 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EKE41021.1 - 0.18 11.8 0.9 3.6 7.6 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKE41021.1 - 0.39 10.6 21.3 0.35 10.7 0.5 5.4 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Rap_GAP PF02145.10 EKE41022.1 - 6.5e-15 55.0 0.0 1.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP HEAT PF02985.17 EKE41022.1 - 0.057 13.5 0.0 0.21 11.7 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat TFIID-18kDa PF02269.11 EKE41023.1 - 2.5e-08 33.6 0.5 3.4e-08 33.2 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF2653 PF10850.3 EKE41023.1 - 0.021 15.1 0.1 1.3 9.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2653) Ras PF00071.17 EKE41024.1 - 1.2e-35 122.2 0.0 1.8e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41024.1 - 7e-08 32.9 0.0 2.2e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE41024.1 - 1.2e-05 24.6 0.0 1.6e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PCI_Csn8 PF10075.4 EKE41025.1 - 0.039 13.7 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF3244 PF11589.3 EKE41025.1 - 0.14 11.9 0.9 1.9 8.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3244) RNA_bind_2 PF10133.4 EKE41026.1 - 0.06 13.3 1.0 5.5 7.1 0.2 2.7 2 0 0 2 2 2 0 Predicted RNA-binding protein PIG-U PF06728.8 EKE41027.1 - 2.8e-22 79.1 53.3 8e-20 71.0 20.9 2.9 1 1 1 3 3 3 2 GPI transamidase subunit PIG-U RasGAP PF00616.14 EKE41028.1 - 3.2e-30 105.2 2.4 3.2e-30 105.2 1.7 3.6 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase WD40 PF00400.27 EKE41029.1 - 2.4e-19 68.4 23.3 0.00016 21.4 0.0 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EKE41029.1 - 0.033 12.3 0.0 0.051 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EKE41029.1 - 0.074 12.4 0.0 2.6 7.4 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain RNA_pol_Rpb5_C PF01191.14 EKE41029.1 - 0.087 12.4 0.3 36 4.0 0.0 3.4 3 0 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain GSIII_N PF12437.3 EKE41030.1 - 1.2e-63 213.4 0.0 2.4e-63 212.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 EKE41030.1 - 4.4e-34 117.8 0.0 7.6e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Arg_repressor PF01316.16 EKE41031.1 - 0.00017 21.0 1.0 0.00032 20.1 0.1 1.9 2 0 0 2 2 2 1 Arginine repressor, DNA binding domain HTH_32 PF13565.1 EKE41031.1 - 0.04 14.7 0.1 0.14 13.0 0.1 2.0 1 1 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 EKE41031.1 - 0.085 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Surf_Ag_VNR PF07244.10 EKE41031.1 - 0.11 12.9 1.0 0.27 11.6 0.2 2.1 1 1 1 2 2 2 0 Surface antigen variable number repeat HTH_24 PF13412.1 EKE41031.1 - 0.16 11.3 1.7 19 4.7 0.2 3.1 2 2 0 2 2 2 0 Winged helix-turn-helix DNA-binding RNA_pol_Rpb2_4 PF04566.8 EKE41031.1 - 0.21 11.4 2.0 0.39 10.5 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 HTH_7 PF02796.10 EKE41031.1 - 0.92 9.4 5.6 0.38 10.6 0.7 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase PNP_UDP_1 PF01048.15 EKE41032.1 - 3e-30 104.9 0.1 3.6e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_19 PF13245.1 EKE41032.1 - 0.12 12.1 0.2 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain RRM_1 PF00076.17 EKE41033.1 - 2.4e-21 75.1 5.3 1.8e-09 37.1 0.3 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41033.1 - 5.5e-14 51.9 0.3 5e-05 23.1 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41033.1 - 3.5e-12 45.9 3.3 4.7e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE41033.1 - 0.00082 19.0 0.5 0.039 13.7 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF3997 PF13162.1 EKE41033.1 - 0.013 15.2 0.1 0.013 15.2 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3997) TOBE_3 PF12857.2 EKE41033.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 TOBE-like domain Arm PF00514.18 EKE41034.1 - 0.0016 18.1 0.0 1.5 8.7 0.0 4.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF383 PF04063.9 EKE41034.1 - 0.0063 16.0 1.7 0.026 14.0 1.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF383) HEAT_2 PF13646.1 EKE41034.1 - 0.0085 16.3 0.1 0.81 10.0 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats FAE1_CUT1_RppA PF08392.7 EKE41035.1 - 6e-98 327.5 0.0 7.5e-98 327.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.10 EKE41035.1 - 3e-10 40.2 0.1 1.7e-09 37.8 0.0 2.2 1 1 1 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.5 EKE41035.1 - 7.1e-10 38.7 0.0 3.6e-09 36.5 0.0 2.2 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.14 EKE41035.1 - 0.00034 19.9 0.0 0.00056 19.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 EKE41035.1 - 0.0043 16.6 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MMtag PF10159.4 EKE41036.1 - 0.047 13.7 9.8 0.067 13.2 1.7 2.5 1 1 1 2 2 2 0 Kinase phosphorylation protein IL1 PF00340.14 EKE41036.1 - 1.4 8.4 10.4 0.043 13.2 2.4 1.8 2 0 0 2 2 2 0 Interleukin-1 / 18 RhoGEF PF00621.15 EKE41037.1 - 1.5e-46 158.5 2.5 3e-46 157.5 1.8 1.5 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EKE41037.1 - 4.2e-15 55.4 9.2 4.2e-15 55.4 6.4 1.9 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 EKE41037.1 - 4.7e-09 36.3 1.4 8.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.11 EKE41037.1 - 1.1e-05 25.3 8.6 3.1e-05 23.8 6.0 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.16 EKE41037.1 - 0.014 15.2 5.0 0.044 13.6 3.4 1.8 1 0 0 1 1 1 0 IBR domain A_thal_3526 PF09713.5 EKE41038.1 - 4.5e-08 33.1 0.2 8.5e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) DUF1523 PF07509.6 EKE41040.1 - 0.041 13.1 0.2 0.082 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) SseC PF04888.7 EKE41040.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Pex24p PF06398.6 EKE41040.1 - 0.99 8.1 7.4 0.74 8.5 0.0 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Vma12 PF11712.3 EKE41040.1 - 1.1 8.9 8.3 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3671 PF12420.3 EKE41040.1 - 1.3 9.0 12.9 8.4 6.4 8.9 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF1700 PF08006.6 EKE41040.1 - 4.4 6.5 14.8 49 3.1 10.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) SAG PF04092.8 EKE41042.1 - 0.052 13.9 1.5 0.11 12.8 1.1 1.6 1 0 0 1 1 1 0 SRS domain PNMA PF14893.1 EKE41042.1 - 0.071 12.1 0.1 0.071 12.1 0.1 2.0 3 0 0 3 3 3 0 PNMA Rap_GAP PF02145.10 EKE41043.1 - 8e-28 97.0 0.1 1.9e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP DUF814 PF05670.8 EKE41045.1 - 5e-21 74.3 0.0 7.7e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Ank_2 PF12796.2 EKE41046.1 - 2.1e-15 56.8 0.1 8.4e-07 29.2 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKE41046.1 - 2.8e-14 53.1 1.5 0.00075 19.9 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE41046.1 - 3e-12 45.4 0.4 5.9e-05 22.9 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EKE41046.1 - 8.4e-12 44.9 0.0 4e-06 26.8 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EKE41046.1 - 3e-11 42.5 0.0 5.1e-06 26.0 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Patatin PF01734.17 EKE41046.1 - 5.7e-10 39.4 0.0 1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Mit_KHE1 PF10173.4 EKE41047.1 - 0.092 12.5 2.5 8.1 6.2 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related PG_binding_4 PF12229.3 EKE41047.1 - 1.6 8.9 9.9 9.9 6.4 0.1 3.1 2 1 1 3 3 3 0 Putative peptidoglycan binding domain PGM_PMM_I PF02878.11 EKE41048.1 - 6.2e-30 103.4 0.0 3.3e-29 101.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EKE41048.1 - 7.3e-25 87.3 0.0 3.4e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EKE41048.1 - 2.3e-20 72.6 0.0 5.2e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EKE41048.1 - 6.8e-09 35.6 0.1 6.1e-08 32.5 0.2 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CK_II_beta PF01214.13 EKE41049.1 - 3.8e-30 104.7 1.7 5.1e-30 104.3 1.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit NAP PF00956.13 EKE41050.1 - 3.8e-18 65.5 1.3 6.5e-18 64.7 0.9 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Cofilin_ADF PF00241.15 EKE41051.1 - 4.4e-31 107.3 0.0 2.2e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein GFRP PF06399.8 EKE41052.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) A2L_zn_ribbon PF08792.5 EKE41052.1 - 0.32 10.5 2.6 9.1 5.8 0.1 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF3550 PF12070.3 EKE41053.1 - 6.2e-74 249.5 20.5 4e-42 144.6 3.4 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3550/UPF0682) Seryl_tRNA_N PF02403.17 EKE41054.1 - 0.0022 17.9 12.4 0.0022 17.9 8.6 10.2 2 1 7 10 10 10 2 Seryl-tRNA synthetase N-terminal domain MFS_1 PF07690.11 EKE41055.1 - 7.4e-22 77.5 40.1 9e-19 67.3 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EKE41055.1 - 7.9e-20 70.9 10.6 7.9e-20 70.9 7.3 3.4 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 Pkinase PF00069.20 EKE41056.1 - 1.2e-68 231.0 0.0 2.4e-68 230.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41056.1 - 1.7e-29 102.7 0.0 2.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41056.1 - 2e-07 30.2 0.0 3.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ribosomal_60s PF00428.14 EKE41057.1 - 1.2e-19 70.4 18.9 1.4e-19 70.3 13.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 EKE41057.1 - 0.0014 18.4 5.7 0.35 10.8 1.0 2.2 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain RRP7 PF12923.2 EKE41057.1 - 0.061 13.3 2.1 0.067 13.2 1.5 1.1 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) AF1Q PF15017.1 EKE41057.1 - 0.15 11.9 2.1 0.13 12.1 0.7 1.5 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Myc_N PF01056.13 EKE41057.1 - 0.28 10.2 1.6 0.27 10.3 1.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF3824 PF12868.2 EKE41057.1 - 1.4 9.8 4.5 2 9.3 3.2 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) MOZART2 PF12926.2 EKE41057.1 - 2.7 7.6 5.9 1.3 8.6 0.7 2.0 1 1 1 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Cofilin_ADF PF00241.15 EKE41058.1 - 6.8e-08 32.4 0.1 8.5e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Imm33 PF15580.1 EKE41058.1 - 0.1 12.1 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 33 Piwi PF02171.12 EKE41059.1 - 1.2e-48 165.6 8.5 1.2e-48 165.6 5.9 1.8 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 EKE41059.1 - 1.4e-16 60.0 1.8 1.4e-16 60.0 1.3 2.3 2 0 0 2 2 2 1 PAZ domain Voltage_CLC PF00654.15 EKE41060.1 - 3.8e-63 213.6 30.0 3.8e-63 213.6 20.8 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EKE41060.1 - 2.1e-05 24.1 0.1 0.093 12.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain CTDII PF01556.13 EKE41061.1 - 0.012 15.4 0.0 0.048 13.5 0.0 2.0 1 0 0 1 1 1 0 DnaJ C terminal domain PfUIS3 PF11567.3 EKE41061.1 - 0.016 15.3 1.2 0.038 14.1 0.5 1.9 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein SRX PF09201.5 EKE41061.1 - 0.053 13.1 0.8 2.7 7.6 0.1 2.6 2 0 0 2 2 2 0 SRX TSGA13 PF14994.1 EKE41062.1 - 0.038 13.1 0.3 0.051 12.7 0.2 1.1 1 0 0 1 1 1 0 Testis-specific gene 13 protein Ebp2 PF05890.7 EKE41064.1 - 4.5e-28 98.3 28.8 5.6e-28 98.0 19.9 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF1940 PF09155.5 EKE41064.1 - 0.41 10.4 4.2 0.29 10.9 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1940) ABC_tran_2 PF12848.2 EKE41064.1 - 1.2 8.9 22.9 0.64 9.8 13.6 2.2 1 1 1 2 2 2 0 ABC transporter DOR PF14839.1 EKE41064.1 - 3.5 7.3 8.7 4.7 6.8 6.0 1.4 1 0 0 1 1 1 0 DOR family Cob_adeno_trans PF01923.13 EKE41064.1 - 3.9 7.2 7.2 1.9 8.2 1.9 2.1 2 0 0 2 2 2 0 Cobalamin adenosyltransferase CENP-H PF05837.7 EKE41064.1 - 7.1 6.8 18.7 2.5 8.3 9.6 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) VWA_2 PF13519.1 EKE41065.1 - 0.0018 18.4 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Nitro_FeMo-Co PF02579.12 EKE41065.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Metallophos PF00149.23 EKE41066.1 - 1.5e-08 34.3 1.1 2.3e-08 33.6 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE41066.1 - 5.5e-05 23.0 0.1 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AMP-binding PF00501.23 EKE41067.1 - 7e-79 265.1 0.0 1e-78 264.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme tRNA_anti-codon PF01336.20 EKE41068.1 - 7e-08 32.2 1.2 1.1e-07 31.6 0.8 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BOF PF04076.8 EKE41068.1 - 0.004 16.9 2.7 0.0072 16.1 0.5 2.0 2 0 0 2 2 2 1 Bacterial OB fold (BOF) protein tRNA_anti-like PF12869.2 EKE41068.1 - 0.044 13.2 1.4 0.056 12.9 1.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like Sulfotransfer_3 PF13469.1 EKE41069.1 - 2.1e-14 54.7 0.0 3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE41069.1 - 2.8e-07 30.0 0.6 6.9e-07 28.7 0.4 1.7 1 1 0 1 1 1 1 Sulfotransferase domain TPR_11 PF13414.1 EKE41070.1 - 5e-26 90.1 24.4 7.1e-17 60.8 4.3 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EKE41070.1 - 2.7e-16 58.3 16.1 8.2e-06 25.2 1.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKE41070.1 - 1e-14 53.1 12.3 8.3e-05 22.2 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41070.1 - 3.6e-06 27.4 5.1 0.00061 20.3 0.8 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKE41070.1 - 4e-06 26.9 0.4 0.15 12.7 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41070.1 - 6.5e-06 25.9 11.1 8.8e-06 25.5 0.4 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKE41070.1 - 1.4e-05 24.9 10.2 0.001 18.9 3.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKE41070.1 - 4.5e-05 23.6 8.1 5.8e-05 23.3 1.6 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41070.1 - 0.00012 21.5 14.3 0.039 13.7 1.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKE41070.1 - 0.0085 15.9 3.7 0.025 14.4 0.0 3.2 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat LTXXQ PF07813.7 EKE41070.1 - 0.022 15.1 1.6 0.022 15.1 1.1 3.1 3 0 0 3 3 3 0 LTXXQ motif family protein TPR_7 PF13176.1 EKE41070.1 - 0.55 10.1 2.5 12 5.9 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat PIN_2 PF10130.4 EKE41070.1 - 1.5 8.8 4.7 0.43 10.6 0.6 2.1 2 0 0 2 2 2 0 PIN domain GET2 PF08690.5 EKE41070.1 - 2.6 7.2 16.9 10 5.2 11.7 2.0 1 1 0 1 1 1 0 GET complex subunit GET2 Zip PF02535.17 EKE41070.1 - 2.9 6.8 5.1 5.7 5.8 3.5 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter MFS_1 PF07690.11 EKE41071.1 - 6.9e-30 103.9 7.4 4.2e-24 84.9 3.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.3 EKE41071.1 - 0.0064 16.5 6.4 0.33 11.0 3.7 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2929) RhoGAP PF00620.22 EKE41072.1 - 2.3e-12 46.7 1.6 2.8e-12 46.5 0.6 1.5 1 1 1 2 2 2 1 RhoGAP domain DUF816 PF05674.7 EKE41072.1 - 0.038 13.7 0.6 0.048 13.3 0.3 1.3 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) RhoGAP PF00620.22 EKE41073.1 - 2.8e-12 46.5 0.0 3.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain GIDA PF01134.17 EKE41073.1 - 0.13 11.0 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Glucose inhibited division protein A DKCLD PF08068.7 EKE41074.1 - 2.9e-27 94.3 0.1 4.4e-26 90.5 0.0 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EKE41074.1 - 1.9e-23 83.2 5.7 1.1e-21 77.4 0.2 3.9 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EKE41074.1 - 7.4e-20 70.4 1.1 1.6e-19 69.4 0.8 1.6 1 0 0 1 1 1 1 PUA domain Cwf_Cwc_15 PF04889.7 EKE41074.1 - 0.15 11.7 23.7 0.22 11.2 16.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 EKE41075.1 - 0.0012 18.2 0.2 0.0015 17.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4083 PF13314.1 EKE41075.1 - 0.0024 17.6 3.8 0.032 14.0 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) Neur_chan_memb PF02932.11 EKE41075.1 - 0.0064 16.4 0.0 0.0094 15.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GRIM-19 PF06212.7 EKE41075.1 - 0.0085 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein EphA2_TM PF14575.1 EKE41075.1 - 0.013 15.9 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain S1FA PF04689.8 EKE41075.1 - 0.017 15.0 0.2 0.017 15.0 0.1 1.6 2 0 0 2 2 2 0 DNA binding protein S1FA DUF1049 PF06305.6 EKE41075.1 - 0.03 13.7 0.0 0.097 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3404 PF11884.3 EKE41075.1 - 0.034 13.0 0.8 0.05 12.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) LRR19-TM PF15176.1 EKE41075.1 - 0.035 13.7 0.4 0.075 12.7 0.3 1.7 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2681 PF10883.3 EKE41075.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Rifin_STEVOR PF02009.11 EKE41075.1 - 0.085 12.4 7.9 0.06 12.9 4.3 1.7 1 1 0 1 1 1 0 Rifin/stevor family PTR2 PF00854.16 EKE41075.1 - 0.11 11.3 0.0 0.74 8.5 0.0 1.9 1 1 0 1 1 1 0 POT family DUF3139 PF11337.3 EKE41075.1 - 0.63 10.3 5.3 0.33 11.2 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Aa_trans PF01490.13 EKE41076.1 - 2.7e-47 161.1 43.3 3.3e-47 160.8 30.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EKE41076.1 - 7.8e-06 24.9 19.8 7.8e-06 24.9 13.8 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family SNF2_N PF00176.18 EKE41080.1 - 1.1e-72 244.4 2.0 1.7e-72 243.7 1.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EKE41080.1 - 6.2e-17 61.0 9.5 9.4e-11 41.2 1.0 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EKE41080.1 - 4.1e-12 45.7 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EKE41080.1 - 1.9e-07 30.2 2.0 6.2e-07 28.5 0.2 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EKE41080.1 - 2e-06 27.7 0.1 2.4e-05 24.2 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKE41080.1 - 0.00014 21.3 0.0 0.00036 20.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE41080.1 - 0.00064 19.8 0.0 0.0022 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cornichon PF03311.9 EKE41081.1 - 1.9e-11 44.1 12.2 2.4e-11 43.8 8.4 1.1 1 0 0 1 1 1 1 Cornichon protein RTC PF01137.16 EKE41083.1 - 1.3e-59 200.7 0.1 1.5e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EKE41083.1 - 2e-31 108.0 0.0 3.3e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Peptidase_M24 PF00557.19 EKE41084.1 - 4.4e-41 140.7 0.0 6.1e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EKE41084.1 - 6.5e-11 42.8 0.0 1.2e-08 35.5 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain HAD_2 PF13419.1 EKE41085.1 - 1.5e-11 44.7 0.0 2.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKE41085.1 - 0.00038 20.1 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EKE41085.1 - 0.039 14.0 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rap_GAP PF02145.10 EKE41089.1 - 5e-46 156.4 2.1 1.7e-45 154.7 1.5 2.0 1 0 0 1 1 1 1 Rap/ran-GAP Ank_2 PF12796.2 EKE41089.1 - 1.5e-28 98.9 3.5 1.3e-12 47.9 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKE41089.1 - 7.2e-28 93.8 3.1 4.8e-05 23.2 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.25 EKE41089.1 - 1.8e-26 90.5 1.5 1.1e-05 24.9 0.0 5.3 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EKE41089.1 - 5.1e-21 74.6 0.5 3.1e-07 30.7 0.1 4.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE41089.1 - 3.3e-18 65.2 0.1 1.5e-07 31.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) bZIP_1 PF00170.16 EKE41089.1 - 0.031 14.2 0.3 0.077 12.9 0.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 EKE41089.1 - 0.046 13.5 0.6 0.11 12.2 0.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper SWIB PF02201.13 EKE41089.1 - 0.05 13.2 0.6 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 SWIB/MDM2 domain UCH PF00443.24 EKE41090.1 - 7e-50 169.6 11.7 1.3e-49 168.7 8.1 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE41090.1 - 5.4e-11 42.4 10.6 1.5e-09 37.7 7.4 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TLD PF07534.11 EKE41091.1 - 0.0015 18.5 0.6 0.01 15.8 0.1 2.2 2 0 0 2 2 2 1 TLD AAA_14 PF13173.1 EKE41091.1 - 0.34 10.8 3.6 12 5.8 2.5 2.4 1 1 0 1 1 1 0 AAA domain DUF4600 PF15372.1 EKE41091.1 - 0.68 10.1 6.9 0.36 11.0 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) COG2 PF06148.6 EKE41092.1 - 1.6e-11 44.1 5.5 3.1e-11 43.2 3.7 1.5 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 KdpD PF02702.12 EKE41092.1 - 0.034 13.2 1.1 0.045 12.8 0.7 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain PHAT PF09246.5 EKE41092.1 - 0.039 13.5 1.2 0.065 12.8 0.8 1.4 1 0 0 1 1 1 0 PHAT SPATA6 PF14909.1 EKE41092.1 - 0.041 13.9 1.6 0.063 13.3 1.0 1.4 1 1 0 1 1 1 0 Spermatogenesis-assoc protein 6 UvrD-helicase PF00580.16 EKE41092.1 - 0.061 12.6 5.3 0.074 12.3 3.7 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DLD PF14878.1 EKE41092.1 - 0.5 10.5 5.4 0.44 10.6 2.7 1.7 1 1 0 1 1 1 0 Death-like domain of SPT6 DUF948 PF06103.6 EKE41092.1 - 1.5 8.7 4.8 3.7 7.4 1.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Actin PF00022.14 EKE41093.1 - 6.2e-103 344.2 0.0 7.8e-103 343.9 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKE41093.1 - 3e-08 32.6 0.0 2.4e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein YozD PF14162.1 EKE41093.1 - 0.0074 16.3 1.4 4.2 7.5 0.2 3.1 3 0 0 3 3 3 2 YozD-like protein Marek_SORF3 PF07153.6 EKE41093.1 - 0.039 12.6 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Secretogranin_V PF05281.6 EKE41093.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Robl_LC7 PF03259.12 EKE41094.1 - 0.00034 20.1 0.0 0.0073 15.8 0.0 2.4 2 1 0 2 2 2 1 Roadblock/LC7 domain DUF4127 PF13552.1 EKE41094.1 - 0.089 11.1 0.0 0.096 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) CodY PF06018.9 EKE41094.1 - 0.1 11.8 0.2 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 CodY GAF-like domain MIF4G PF02854.14 EKE41096.1 - 0.00034 20.1 11.0 0.00034 20.1 7.7 4.9 3 2 2 5 5 5 3 MIF4G domain QueF PF14489.1 EKE41096.1 - 0.83 9.6 4.9 0.31 11.0 0.5 2.6 3 0 0 3 3 3 0 QueF-like protein Dimer_Tnp_hAT PF05699.9 EKE41097.1 - 0.005 16.4 0.3 0.024 14.2 0.2 2.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ion_trans_2 PF07885.11 EKE41099.1 - 2e-13 49.8 5.4 2e-13 49.8 3.7 2.4 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.13 EKE41099.1 - 2.4e-09 37.1 0.0 0.00011 22.2 0.3 2.6 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.16 EKE41099.1 - 0.0014 18.2 0.0 0.93 9.1 0.0 3.1 3 0 0 3 3 3 2 TrkA-C domain DUF2179 PF10035.4 EKE41099.1 - 0.024 14.2 1.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) A_deaminase PF00962.17 EKE41100.1 - 5.8e-70 235.8 0.4 6.9e-70 235.5 0.3 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase TLD PF07534.11 EKE41101.1 - 0.0018 18.2 1.7 0.0024 17.8 0.1 2.1 2 1 0 2 2 2 1 TLD Mut7-C PF01927.11 EKE41102.1 - 1.1e-27 96.7 0.3 1.5e-27 96.4 0.2 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain zf-UBP PF02148.14 EKE41102.1 - 0.0084 16.2 0.4 0.016 15.2 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_4 PF13894.1 EKE41102.1 - 0.18 12.1 1.3 3.5 8.1 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EKE41102.1 - 0.25 11.4 3.5 11 6.1 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RanBP PF00641.13 EKE41102.1 - 2.8 7.1 8.2 0.36 9.9 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pkinase PF00069.20 EKE41103.1 - 6.3e-35 120.5 0.7 1.2e-34 119.6 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41103.1 - 9.6e-30 103.5 0.9 1.4e-29 103.0 0.3 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Patatin PF01734.17 EKE41104.1 - 2.9e-12 46.9 0.2 6.3e-12 45.8 0.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase TGS PF02824.16 EKE41105.1 - 3.6e-10 39.5 0.0 7.1e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EKE41105.1 - 4.7e-09 36.2 1.5 6.9e-09 35.6 0.3 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE41105.1 - 0.00035 19.8 0.3 0.0021 17.3 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EKE41105.1 - 0.00077 20.2 3.1 0.00082 20.1 0.6 2.0 1 1 0 2 2 2 1 AAA domain Miro PF08477.8 EKE41105.1 - 0.00079 19.9 0.1 0.0032 17.9 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EKE41105.1 - 0.00088 19.5 0.7 0.0018 18.6 0.5 1.7 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EKE41105.1 - 0.0011 17.8 0.0 0.0025 16.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 EKE41105.1 - 0.0029 17.9 1.5 0.0057 16.9 0.6 1.8 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EKE41105.1 - 0.0069 15.6 0.7 0.02 14.1 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EKE41105.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EKE41105.1 - 0.027 14.1 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EKE41105.1 - 0.031 13.7 0.4 2.4 7.5 0.1 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EKE41105.1 - 0.032 13.6 3.4 0.24 10.8 2.4 2.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKE41105.1 - 0.081 13.0 0.2 0.22 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EKE41105.1 - 2.9 8.1 10.8 39 4.4 7.4 2.3 1 1 0 1 1 1 0 AAA domain Mob1_phocein PF03637.12 EKE41106.1 - 9.1e-65 217.5 0.5 1.1e-64 217.3 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Fe_hyd_lg_C PF02906.9 EKE41107.1 - 3.9e-43 147.7 11.1 7.8e-31 107.3 2.2 2.2 1 1 1 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain PDGF PF00341.12 EKE41107.1 - 0.61 10.2 4.9 0.26 11.4 0.3 2.5 2 0 0 2 2 2 0 PDGF/VEGF domain zf-C3HC4_3 PF13920.1 EKE41108.1 - 1.1e-05 24.9 9.2 1.1e-05 24.9 6.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE41108.1 - 6.4e-05 22.6 10.4 6.4e-05 22.6 7.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE41108.1 - 0.00032 20.6 9.4 0.00032 20.6 6.5 2.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE41108.1 - 0.00073 19.1 10.5 0.00073 19.1 7.3 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EKE41108.1 - 0.0023 17.4 4.3 0.0023 17.4 3.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EKE41108.1 - 0.0087 15.8 11.0 0.0087 15.8 7.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EKE41108.1 - 0.083 12.7 16.2 0.39 10.6 9.0 2.9 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EKE41108.1 - 0.27 10.9 9.2 0.051 13.3 3.2 2.4 3 1 0 3 3 3 0 RING-type zinc-finger zf-B_box PF00643.19 EKE41108.1 - 4.3 7.3 9.9 0.73 9.7 2.1 2.3 2 0 0 2 2 2 0 B-box zinc finger DZR PF12773.2 EKE41108.1 - 9.6 6.1 11.6 21 5.0 8.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon Sep15_SelM PF08806.6 EKE41109.1 - 0.00018 21.1 0.1 0.00024 20.8 0.1 1.1 1 0 0 1 1 1 1 Sep15/SelM redox domain DUF1938 PF09153.5 EKE41109.1 - 0.094 12.5 0.1 0.33 10.7 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1938) Pkinase PF00069.20 EKE41110.1 - 4.3e-39 134.2 0.1 5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41110.1 - 7.2e-16 58.0 0.0 8.6e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE41110.1 - 3.1e-05 23.8 0.0 0.006 16.3 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EKE41110.1 - 0.025 13.6 0.0 0.072 12.1 0.0 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKE41110.1 - 0.076 11.9 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like CTDII PF01556.13 EKE41111.1 - 2.8e-21 75.1 2.9 4.2e-17 61.8 0.1 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKE41111.1 - 2.1e-13 50.0 13.3 3.8e-13 49.2 9.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Lar_restr_allev PF14354.1 EKE41111.1 - 0.45 10.8 11.4 5.9 7.2 1.3 3.4 2 2 0 2 2 2 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.1 EKE41111.1 - 1.3 8.7 7.1 15 5.3 2.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EKE41111.1 - 3.3 7.5 10.6 16 5.4 1.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.1 EKE41111.1 - 7.3 7.0 9.1 45 4.5 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-C4_Topoisom PF01396.14 EKE41111.1 - 9.9 5.7 13.9 18 4.9 0.2 4.1 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger PMI_typeI PF01238.16 EKE41112.1 - 1.8e-41 142.3 2.6 2.3e-37 128.8 1.8 3.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I DNA_alkylation PF08713.6 EKE41113.1 - 3.2e-25 88.9 0.0 4.1e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme Hexokinase_1 PF00349.16 EKE41114.1 - 4.2e-08 32.7 0.1 4.4e-08 32.7 0.1 1.0 1 0 0 1 1 1 1 Hexokinase M16C_assoc PF08367.6 EKE41114.1 - 0.038 12.8 0.0 0.038 12.8 0.0 1.0 1 0 0 1 1 1 0 Peptidase M16C associated ThiF PF00899.16 EKE41115.1 - 5.8e-38 129.7 0.0 1.4e-37 128.5 0.0 1.6 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EKE41115.1 - 1.4e-16 59.7 0.1 2.6e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EKE41115.1 - 8e-14 51.1 0.1 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EKE41115.1 - 6.1e-12 44.7 3.4 1.5e-11 43.4 2.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EKE41115.1 - 0.00017 21.6 0.0 0.00065 19.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 EKE41115.1 - 0.0003 20.8 0.2 0.00077 19.5 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain MoeZ_MoeB PF05237.8 EKE41115.1 - 0.00097 18.6 1.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 MoeZ/MoeB domain Pyr_redox PF00070.22 EKE41115.1 - 0.046 14.1 0.2 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Stk19 PF10494.4 EKE41117.1 - 4.2e-07 29.6 3.5 5.6e-07 29.2 2.4 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 EppA_BapA PF07268.6 EKE41117.1 - 0.1 12.2 3.5 0.13 11.9 0.9 2.1 1 1 1 2 2 2 0 Exported protein precursor (EppA/BapA) Tic20 PF09685.5 EKE41118.1 - 5.6e-09 35.9 10.5 6.6e-09 35.7 7.3 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF2834 PF11196.3 EKE41118.1 - 0.031 14.4 2.6 0.031 14.4 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) DUF4064 PF13273.1 EKE41118.1 - 0.041 13.9 9.1 0.72 9.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) VirB3 PF05101.8 EKE41118.1 - 9.7 6.2 8.1 1.8 8.6 2.2 2.0 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein Cornichon PF03311.9 EKE41119.1 - 8.8e-28 97.0 8.8 1.2e-27 96.5 6.1 1.2 1 0 0 1 1 1 1 Cornichon protein DUF1282 PF06930.7 EKE41119.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) DUF4282 PF14110.1 EKE41119.1 - 3.4 7.9 6.1 11 6.2 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) TLD PF07534.11 EKE41120.1 - 0.00045 20.2 1.6 0.0007 19.6 0.3 1.9 2 0 0 2 2 2 1 TLD Ras PF00071.17 EKE41121.1 - 6.5e-39 132.9 0.4 5e-37 126.7 0.3 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKE41121.1 - 2.6e-16 60.2 0.1 3.8e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKE41121.1 - 6.5e-05 22.8 0.1 7.9e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EKE41121.1 - 0.00031 20.0 0.1 0.00034 19.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41121.1 - 0.0073 15.7 0.6 0.044 13.2 0.1 2.2 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain SNARE_assoc PF09335.6 EKE41123.1 - 3.5e-22 78.8 4.4 3.5e-22 78.8 3.0 2.4 3 1 0 3 3 3 1 SNARE associated Golgi protein GCC2_GCC3 PF07699.8 EKE41124.1 - 2.6e-06 26.8 8.5 2.6e-06 26.8 5.9 6.6 2 2 3 5 5 5 4 GCC2 and GCC3 NCD3G PF07562.9 EKE41124.1 - 0.28 10.9 51.8 0.081 12.6 1.4 6.6 2 2 4 7 7 7 0 Nine Cysteines Domain of family 3 GPCR Phospholip_B PF04916.8 EKE41125.1 - 1.8e-106 356.4 6.7 2.3e-106 356.1 4.6 1.1 1 0 0 1 1 1 1 Phospholipase B Synaptobrevin PF00957.16 EKE41126.1 - 1.4e-22 79.0 6.4 1.6e-22 78.8 4.5 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 EKE41126.1 - 0.00022 20.8 3.8 0.00023 20.7 2.6 1.0 1 0 0 1 1 1 1 Retroviral envelope protein DUF912 PF06024.7 EKE41126.1 - 0.00071 19.5 1.3 0.00084 19.3 0.9 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2951 PF11166.3 EKE41126.1 - 0.0023 17.7 2.3 0.0027 17.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) Rifin_STEVOR PF02009.11 EKE41126.1 - 0.0075 15.9 2.6 0.0084 15.7 1.8 1.1 1 0 0 1 1 1 1 Rifin/stevor family Herpes_UL45 PF05473.7 EKE41126.1 - 0.0099 15.3 0.0 0.0099 15.3 0.0 1.0 1 0 0 1 1 1 1 UL45 protein DUF2031 PF09592.5 EKE41126.1 - 0.01 15.0 0.6 0.011 14.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2031) DUF4199 PF13858.1 EKE41126.1 - 0.011 15.6 0.3 0.012 15.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Shisa PF13908.1 EKE41126.1 - 0.014 15.6 0.4 0.015 15.5 0.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EVI2A PF05399.6 EKE41126.1 - 0.02 14.1 0.7 0.023 13.9 0.5 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF3753 PF12575.3 EKE41126.1 - 0.022 14.5 5.4 0.03 14.0 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) BatD PF13584.1 EKE41126.1 - 0.023 13.2 0.2 0.026 13.1 0.2 1.0 1 0 0 1 1 1 0 Oxygen tolerance SseC PF04888.7 EKE41126.1 - 0.032 13.5 3.1 0.035 13.4 2.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family EMP24_GP25L PF01105.19 EKE41126.1 - 0.036 13.7 1.4 0.048 13.3 0.9 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2839 PF10999.3 EKE41126.1 - 0.038 14.0 0.4 0.047 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) NPCC PF08058.6 EKE41126.1 - 0.04 13.7 0.4 0.041 13.7 0.3 1.0 1 0 0 1 1 1 0 Nuclear pore complex component DUF2207 PF09972.4 EKE41126.1 - 0.056 12.0 0.2 0.06 11.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3899 PF13038.1 EKE41126.1 - 0.074 13.2 0.4 0.086 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF1191 PF06697.7 EKE41126.1 - 0.083 11.6 0.2 0.079 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM154 PF15102.1 EKE41126.1 - 0.083 12.5 0.2 0.091 12.4 0.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family Rhabdo_glycop PF00974.13 EKE41126.1 - 0.088 11.0 0.4 0.084 11.0 0.3 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Corona_S2 PF01601.11 EKE41126.1 - 0.089 10.8 2.7 0.086 10.9 1.8 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein COX6A PF02046.10 EKE41126.1 - 0.091 12.6 0.4 0.098 12.5 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa YukC PF10140.4 EKE41126.1 - 0.11 10.9 0.9 0.13 10.8 0.6 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC XhlA PF10779.4 EKE41126.1 - 0.13 12.1 12.8 0.21 11.5 8.8 1.4 1 1 0 1 1 1 0 Haemolysin XhlA Spore_III_AB PF09548.5 EKE41126.1 - 0.13 11.9 1.0 0.23 11.1 0.7 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF2077 PF09850.4 EKE41126.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Baculo_E56 PF04639.7 EKE41126.1 - 0.14 10.7 0.2 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope FlaC_arch PF05377.6 EKE41126.1 - 0.19 11.6 1.8 0.25 11.2 0.5 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) TMEM156 PF15106.1 EKE41126.1 - 0.33 10.1 2.4 0.36 10.0 1.7 1.1 1 0 0 1 1 1 0 TMEM156 protein family T2SF PF00482.18 EKE41126.1 - 1.6 8.6 3.5 2.4 8.0 2.5 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF2970 PF11174.3 EKE41126.1 - 1.7 8.2 7.3 2.6 7.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Sigma_reg_N PF13800.1 EKE41126.1 - 3.2 7.8 5.7 6.1 6.9 4.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Glycophorin_A PF01102.13 EKE41126.1 - 3.3 7.4 5.6 4 7.2 3.9 1.3 1 1 0 1 1 1 0 Glycophorin A LRR19-TM PF15176.1 EKE41126.1 - 7.9 6.2 7.1 8.6 6.1 4.7 1.3 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain PH PF00169.24 EKE41127.1 - 9.5e-12 45.0 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKE41127.1 - 0.00047 20.3 1.7 0.00047 20.3 1.2 1.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EKE41127.1 - 0.0088 16.1 0.1 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Sld5 PF05916.6 EKE41129.1 - 5.7e-19 68.4 0.2 1.6e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 GINS complex protein Acetyltransf_11 PF13720.1 EKE41129.1 - 0.14 12.4 0.1 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FNIP PF05725.7 EKE41130.1 - 0.48 10.4 10.6 0.052 13.5 0.9 4.0 3 1 1 4 4 4 0 FNIP Repeat C2 PF00168.25 EKE41131.1 - 4.9e-18 64.7 0.0 6.2e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 C2 domain Aminotran_1_2 PF00155.16 EKE41132.1 - 5.6e-45 153.8 0.0 5.2e-29 101.3 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Sec2p PF06428.6 EKE41133.1 - 0.071 12.9 5.1 0.32 10.8 3.5 2.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Rootletin PF15035.1 EKE41133.1 - 0.28 11.1 8.2 0.28 11.1 4.7 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.6 EKE41133.1 - 7.1 6.5 8.6 2.3 8.1 2.2 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Rav1p_C PF12234.3 EKE41134.1 - 3.7e-46 157.5 3.5 9.1e-45 152.9 2.4 2.5 1 1 0 1 1 1 1 RAVE protein 1 C terminal SecA_PP_bind PF01043.15 EKE41134.1 - 0.0013 19.0 0.1 0.016 15.5 0.0 2.8 2 0 0 2 2 2 1 SecA preprotein cross-linking domain WD40 PF00400.27 EKE41134.1 - 0.0026 17.5 6.8 2.7 8.0 0.0 5.6 8 0 0 8 8 8 2 WD domain, G-beta repeat TLD PF07534.11 EKE41135.1 - 1.5e-08 34.7 0.3 2.9e-08 33.7 0.2 1.6 1 0 0 1 1 1 1 TLD ALMT PF11744.3 EKE41135.1 - 1.2 7.6 4.6 1.7 7.1 3.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.20 EKE41136.1 - 7.1e-76 254.7 0.3 7.1e-76 254.7 0.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41136.1 - 3.8e-47 160.5 0.0 5.4e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 EKE41136.1 - 3.6e-11 42.7 0.1 8e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.1 EKE41136.1 - 0.00047 19.2 0.0 0.0012 17.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKE41136.1 - 0.0017 18.1 0.1 0.03 14.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EKE41136.1 - 0.0067 15.5 0.2 0.014 14.4 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKE41136.1 - 0.027 13.7 1.6 0.22 10.8 1.1 2.2 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_Tyr PF07714.12 EKE41137.1 - 8.6e-33 113.4 0.1 1.3e-32 112.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41137.1 - 1.6e-27 96.3 1.0 1.6e-27 96.3 0.7 1.8 2 0 0 2 2 2 1 Protein kinase domain Metallophos PF00149.23 EKE41138.1 - 4.4e-05 22.9 1.8 0.00011 21.6 1.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-RING_2 PF13639.1 EKE41139.1 - 1.4e-11 44.0 10.3 3.4e-11 42.7 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE41139.1 - 1.9e-07 31.0 12.6 5.5e-07 29.5 8.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE41139.1 - 1e-06 28.2 7.1 2e-06 27.3 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE41139.1 - 1.1e-06 28.2 10.4 2.5e-06 27.0 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKE41139.1 - 1.4e-06 28.2 9.7 4.9e-06 26.5 6.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EKE41139.1 - 3.1e-05 23.6 10.6 6.6e-05 22.5 7.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKE41139.1 - 0.001 18.8 3.9 0.0022 17.7 2.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CUE PF02845.11 EKE41139.1 - 0.0012 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain FANCL_C PF11793.3 EKE41139.1 - 0.2 11.6 10.2 3.5 7.6 7.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain DUF1036 PF06282.6 EKE41141.1 - 0.036 14.3 0.2 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1036) RhoGEF PF00621.15 EKE41142.1 - 3.5e-12 46.5 7.7 3.5e-12 46.5 5.4 2.4 3 0 0 3 3 3 1 RhoGEF domain Cyc-maltodext_C PF10438.4 EKE41142.1 - 0.69 10.0 4.0 1.7 8.7 0.2 3.0 1 1 2 3 3 3 0 Cyclo-malto-dextrinase C-terminal domain DUF2890 PF11081.3 EKE41143.1 - 0.00028 20.9 0.3 0.00032 20.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) SF3b1 PF08920.5 EKE41143.1 - 0.067 13.2 1.5 0.21 11.6 0.4 1.9 1 1 1 2 2 2 0 Splicing factor 3B subunit 1 Gelsolin PF00626.17 EKE41144.1 - 2.8e-50 167.9 29.0 7.4e-11 41.5 0.0 9.4 10 0 0 10 10 10 7 Gelsolin repeat LRR_4 PF12799.2 EKE41144.1 - 1.3e-23 82.0 32.3 1.6e-09 37.1 0.1 7.1 3 3 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE41144.1 - 1.9e-18 65.9 27.9 5.2e-05 22.9 0.5 4.6 3 1 1 4 4 4 4 Leucine rich repeat VHP PF02209.14 EKE41144.1 - 2.7e-13 49.3 4.2 1.3e-12 47.1 2.9 2.4 1 0 0 1 1 1 1 Villin headpiece domain LRR_1 PF00560.28 EKE41144.1 - 1e-06 27.8 31.4 5.6 7.4 0.0 10.6 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 EKE41144.1 - 0.00011 21.7 16.6 18 6.1 0.0 8.7 9 0 0 9 9 9 1 Leucine rich repeat Ras PF00071.17 EKE41146.1 - 4.9e-45 152.8 0.9 6.2e-45 152.4 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41146.1 - 1.2e-15 58.0 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41146.1 - 1.7e-10 40.4 0.1 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKE41146.1 - 5e-07 29.1 0.0 7.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE41146.1 - 1.2e-06 28.0 0.2 8.2e-05 22.1 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE41146.1 - 2e-06 27.7 0.0 3.6e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE41146.1 - 5.6e-05 22.4 0.1 6.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EKE41146.1 - 0.02 14.1 0.1 0.084 12.1 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_33 PF13671.1 EKE41146.1 - 0.074 12.9 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 EKE41146.1 - 0.096 12.2 0.4 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pro_isomerase PF00160.16 EKE41147.1 - 1.2e-45 155.5 0.2 1.4e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TLD PF07534.11 EKE41148.1 - 2.2e-07 30.9 2.0 5.6e-07 29.6 1.4 1.6 1 0 0 1 1 1 1 TLD DUF3552 PF12072.3 EKE41148.1 - 0.0056 15.9 3.9 0.01 15.0 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF1572 PF07609.6 EKE41148.1 - 0.023 14.2 3.6 0.48 9.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) RNase_H PF00075.19 EKE41148.1 - 0.032 14.5 2.9 4.3 7.6 2.0 2.5 1 1 0 1 1 1 0 RNase H HAUS-augmin3 PF14932.1 EKE41148.1 - 0.096 11.8 9.4 0.099 11.8 5.2 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4037 PF13228.1 EKE41148.1 - 0.13 12.4 0.0 0.49 10.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) IncA PF04156.9 EKE41148.1 - 0.47 10.0 8.7 0.075 12.6 3.4 1.6 2 0 0 2 2 2 0 IncA protein DBB PF14545.1 EKE41149.1 - 0.016 14.7 0.1 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, Pkinase_Tyr PF07714.12 EKE41150.1 - 4.7e-33 114.3 0.1 5.7e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41150.1 - 2.4e-28 99.0 0.2 3.4e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EKE41150.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_3 PF01764.20 EKE41151.1 - 2.5e-06 27.1 0.0 4.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EKE41151.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2116 PF09889.4 EKE41152.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.7 3 1 1 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Adeno_E3_CR2 PF02439.10 EKE41152.1 - 0.28 10.7 5.7 1.1 8.8 3.9 2.0 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2061 PF09834.4 EKE41152.1 - 1 9.6 8.5 8.5 6.6 1.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) ETRAMP PF09716.5 EKE41152.1 - 5.5 7.0 9.3 16 5.5 6.4 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Synaptobrevin PF00957.16 EKE41152.1 - 5.9 6.5 5.6 0.51 9.9 0.4 1.9 2 0 0 2 2 2 0 Synaptobrevin HSP70 PF00012.15 EKE41153.1 - 4.3e-80 269.3 11.6 5e-80 269.1 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE41153.1 - 3e-05 22.7 0.2 3e-05 22.7 0.1 2.2 3 1 0 3 3 3 1 MreB/Mbl protein DUF4445 PF14574.1 EKE41153.1 - 0.00049 18.4 0.7 1 7.5 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4445) FtsA PF14450.1 EKE41153.1 - 0.0011 18.7 1.3 0.87 9.4 0.4 3.2 2 1 0 2 2 2 2 Cell division protein FtsA DUF1376 PF07120.6 EKE41153.1 - 0.13 12.3 1.4 18 5.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) Snapin_Pallidin PF14712.1 EKE41153.1 - 0.91 9.8 7.0 0.21 11.8 2.0 2.2 2 0 0 2 2 2 0 Snapin/Pallidin NTR2 PF15458.1 EKE41153.1 - 3.4 6.8 22.1 0.024 13.8 5.6 2.5 3 0 0 3 3 3 0 Nineteen complex-related protein 2 Pkinase PF00069.20 EKE41154.1 - 5.1e-15 55.3 0.6 6.2e-15 55.0 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EKE41154.1 - 7.9e-13 48.1 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EKE41154.1 - 6.6e-12 45.0 0.2 7.4e-12 44.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE41154.1 - 7.1e-09 35.0 0.0 1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE41154.1 - 8e-09 35.5 0.0 0.00018 21.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EKE41154.1 - 0.00018 20.8 0.5 0.00022 20.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 EKE41154.1 - 0.00029 20.4 0.2 0.017 14.6 0.0 2.2 1 1 1 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EKE41154.1 - 0.00047 18.9 0.5 0.034 12.8 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EKE41154.1 - 0.0058 15.8 0.1 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Kinase-like PF14531.1 EKE41154.1 - 0.037 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Topo_C_assoc PF14370.1 EKE41155.1 - 0.086 12.5 0.5 0.25 11.0 0.1 2.1 1 1 1 2 2 2 0 C-terminal topoisomerase domain FtsX PF02687.16 EKE41156.1 - 2.2e-21 75.8 43.4 5.7e-14 51.9 11.5 4.0 4 1 1 5 5 5 2 FtsX-like permease family Flavin_Reduct PF01613.13 EKE41157.1 - 5.1e-06 26.4 0.0 6.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain UBA PF00627.26 EKE41158.1 - 1.3e-09 37.6 4.5 1.6e-07 30.9 0.1 3.5 3 1 0 3 3 3 2 UBA/TS-N domain LRR_8 PF13855.1 EKE41158.1 - 0.00074 19.2 4.8 0.00074 19.2 3.3 3.7 3 2 0 3 3 3 1 Leucine rich repeat NTF2 PF02136.15 EKE41158.1 - 0.0084 16.4 0.6 0.024 15.0 0.4 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 EKE41158.1 - 0.015 14.8 0.2 6.1 6.4 0.0 3.5 3 0 0 3 3 3 0 UBA-like domain LRR_4 PF12799.2 EKE41158.1 - 7.5 6.3 24.5 0.6 9.8 3.7 4.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) SAGA-Tad1 PF12767.2 EKE41159.1 - 4.1e-09 36.4 0.0 4.7e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Ribosomal_L23 PF00276.15 EKE41160.1 - 1.2e-16 60.4 3.5 5.8e-16 58.2 2.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EKE41160.1 - 0.0028 17.6 3.1 0.0028 17.6 2.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain IF-2B PF01008.12 EKE41160.1 - 0.0057 15.6 0.1 0.0059 15.6 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Bot1p PF12298.3 EKE41160.1 - 0.048 13.6 0.4 0.073 13.0 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic mitochondrial regulator protein TroA PF01297.12 EKE41160.1 - 0.17 11.0 0.5 0.24 10.5 0.1 1.4 2 0 0 2 2 2 0 Periplasmic solute binding protein family zf-RING_2 PF13639.1 EKE41161.1 - 1.3e-10 40.8 9.3 2.2e-10 40.1 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKE41161.1 - 1.6e-08 34.1 6.3 2.6e-08 33.3 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKE41161.1 - 1.6e-07 31.3 7.7 8e-07 29.0 5.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKE41161.1 - 4.4e-07 29.8 7.4 9.6e-07 28.7 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE41161.1 - 1.3e-06 27.9 5.4 2.7e-06 26.9 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE41161.1 - 6.1e-05 22.8 3.1 0.00023 20.9 2.3 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EKE41161.1 - 6.9e-05 22.4 6.2 0.00015 21.4 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKE41161.1 - 0.00071 19.3 2.5 0.0069 16.1 1.8 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EKE41161.1 - 0.0027 17.4 3.1 0.0071 16.0 2.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EKE41161.1 - 0.0045 16.5 4.7 0.0085 15.6 3.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EKE41161.1 - 0.0071 16.0 4.0 0.0084 15.8 0.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 EKE41161.1 - 0.063 13.2 8.5 1.4 8.9 5.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Cys_rich_CPXG PF14255.1 EKE41161.1 - 0.086 12.6 6.8 0.51 10.1 1.4 2.8 2 1 0 2 2 2 0 Cysteine-rich CPXCG RINGv PF12906.2 EKE41161.1 - 0.29 11.2 5.1 0.66 10.0 3.5 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EKE41161.1 - 0.9 9.5 7.5 1.8 8.6 5.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EKE41161.1 - 2.1 7.9 5.8 6.7 6.3 4.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain C1_1 PF00130.17 EKE41161.1 - 2.9 7.7 7.7 1.4 8.6 3.3 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EKE41161.1 - 4.6 7.0 9.0 31 4.4 6.2 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF4209 PF13910.1 EKE41162.1 - 6.6e-25 87.0 0.9 3.7e-21 74.9 0.6 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Beach PF02138.13 EKE41163.1 - 3.1e-50 171.1 1.3 4.2e-50 170.6 0.9 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EKE41163.1 - 0.0017 18.1 7.7 0.013 15.3 0.5 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 EKE41163.1 - 0.11 11.5 1.0 2 7.4 0.1 2.2 1 1 0 2 2 2 0 CPSF A subunit region TLD PF07534.11 EKE41164.1 - 1.4e-06 28.3 0.9 2.9e-06 27.3 0.7 1.6 1 0 0 1 1 1 1 TLD Reo_sigmaC PF04582.7 EKE41164.1 - 0.15 11.2 0.7 0.26 10.4 0.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 EKE41164.1 - 0.37 11.2 9.9 0.086 13.2 2.0 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 EKE41164.1 - 0.64 9.8 6.1 3.8 7.3 4.2 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EKE41164.1 - 0.69 9.4 12.2 7 6.2 8.5 2.1 1 1 0 1 1 1 0 IncA protein COG2 PF06148.6 EKE41164.1 - 2.8 7.8 11.1 4.8 7.0 0.9 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ISG65-75 PF11727.3 EKE41164.1 - 4.1 6.3 9.6 0.51 9.3 3.2 1.9 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.7 EKE41164.1 - 5.5 6.8 11.8 1.5 8.6 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CH PF00307.26 EKE41165.1 - 2.9e-07 30.4 5.1 0.033 14.2 0.0 4.9 4 1 0 4 4 4 2 Calponin homology (CH) domain Pkinase_Tyr PF07714.12 EKE41166.1 - 5.2e-53 179.7 0.3 8.2e-53 179.1 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41166.1 - 1.4e-52 178.4 0.7 2.3e-52 177.7 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain GCC2_GCC3 PF07699.8 EKE41166.1 - 2.4e-09 36.6 67.8 2.9e-06 26.7 7.3 36.8 10 5 24 35 35 35 15 GCC2 and GCC3 Kinase-like PF14531.1 EKE41166.1 - 0.00041 19.4 0.0 0.00061 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like NCD3G PF07562.9 EKE41166.1 - 0.0016 18.1 7.5 0.0016 18.1 5.2 35.7 18 12 13 38 38 38 10 Nine Cysteines Domain of family 3 GPCR Kdo PF06293.9 EKE41166.1 - 0.04 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vpu PF00558.14 EKE41166.1 - 0.059 12.9 4.2 0.19 11.3 2.9 1.8 1 0 0 1 1 1 0 Vpu protein Baculo_11_kDa PF06143.6 EKE41166.1 - 1.6 8.1 5.8 4.3 6.7 4.1 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family APH PF01636.18 EKE41166.1 - 1.7 8.3 0.0 2.5 7.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RhoGEF PF00621.15 EKE41167.1 - 3.1e-31 108.6 12.1 3.1e-31 108.6 8.4 2.8 3 0 0 3 3 3 2 RhoGEF domain zf-Di19 PF05605.7 EKE41168.1 - 1.3e-05 25.1 11.1 8.7e-05 22.5 0.1 3.3 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding IncA PF04156.9 EKE41168.1 - 0.01 15.4 27.1 0.22 11.1 12.8 2.3 1 1 1 2 2 2 0 IncA protein zf-C2H2_4 PF13894.1 EKE41168.1 - 0.028 14.7 5.1 1.4 9.4 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger HTH_27 PF13463.1 EKE41168.1 - 0.087 13.1 0.2 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain V_ATPase_I PF01496.14 EKE41168.1 - 0.21 9.4 14.8 0.26 9.1 10.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EKE41168.1 - 0.31 10.0 20.7 0.58 9.1 14.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 LMBR1 PF04791.11 EKE41168.1 - 0.5 8.8 3.9 0.5 8.8 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ADIP PF11559.3 EKE41168.1 - 1.1 9.1 25.9 0.084 12.7 8.3 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-C3HC4_3 PF13920.1 EKE41170.1 - 3.9e-10 39.2 6.2 5.8e-10 38.6 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE41170.1 - 2.5e-09 37.0 10.3 4.4e-09 36.2 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE41170.1 - 1.7e-07 30.9 8.6 1.7e-07 30.9 5.9 1.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EKE41170.1 - 5.9e-07 29.1 8.5 5.9e-07 29.1 5.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EKE41170.1 - 9.8e-07 28.3 12.5 1.8e-06 27.5 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE41170.1 - 1.4e-06 28.0 10.6 3e-06 26.9 7.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EKE41170.1 - 1.1e-05 25.0 1.8 1.1e-05 25.0 1.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EKE41170.1 - 0.0092 15.7 7.9 0.023 14.4 4.1 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EKE41170.1 - 0.033 13.6 9.2 0.097 12.2 6.4 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EKE41170.1 - 0.048 13.1 4.8 0.21 11.1 3.6 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EKE41170.1 - 0.8 9.3 11.8 1.4 8.5 6.6 2.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EKE41170.1 - 6.5 6.3 13.4 1.1e+02 2.4 9.3 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Mei5 PF10376.4 EKE41171.1 - 3.3e-07 30.0 7.6 5.5e-07 29.3 5.2 1.3 1 1 0 1 1 1 1 Double-strand recombination repair protein Herpes_UL6 PF01763.11 EKE41171.1 - 0.019 13.2 2.0 0.022 12.9 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Mu-like_Pro PF10123.4 EKE41171.1 - 0.14 11.5 1.0 1.3 8.4 0.0 2.0 1 1 1 2 2 2 0 Mu-like prophage I protein Pkinase PF00069.20 EKE41172.1 - 8.3e-49 166.0 0.1 1.4e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41172.1 - 1.3e-46 158.8 0.0 2.1e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.8 EKE41172.1 - 0.00069 18.3 117.8 0.012 14.2 12.4 4.9 1 1 2 3 3 3 3 Giardia variant-specific surface protein Kdo PF06293.9 EKE41172.1 - 0.081 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.17 EKE41173.1 - 1.6e-16 60.1 0.1 1.9e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41173.1 - 1.2e-11 45.1 0.0 3.4e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE41173.1 - 2e-07 30.3 0.1 2.6e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MobB PF03205.9 EKE41173.1 - 0.03 14.0 0.6 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EKE41173.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKE41173.1 - 0.06 13.6 4.4 1.3 9.3 3.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 EKE41173.1 - 0.063 13.4 0.5 1.8 8.7 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EKE41173.1 - 0.083 12.8 0.1 0.58 10.1 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE41173.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EKE41173.1 - 0.16 11.7 0.9 0.33 10.7 0.6 2.0 1 1 0 1 1 1 0 Dynamin family Pkinase PF00069.20 EKE41174.1 - 9.3e-06 24.9 2.0 1.3e-05 24.4 1.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41174.1 - 2e-05 23.8 0.4 3.5e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LIM PF00412.17 EKE41175.1 - 1.9e-24 85.4 23.2 4.7e-13 48.9 3.1 3.6 3 1 0 3 3 3 2 LIM domain zf-ribbon_3 PF13248.1 EKE41175.1 - 6.6e-10 37.8 15.3 1.4e-07 30.5 5.6 5.8 4 3 2 6 6 6 3 zinc-ribbon domain DZR PF12773.2 EKE41175.1 - 1.9e-07 30.7 34.4 1.6e-06 27.8 0.9 4.6 2 1 0 2 2 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EKE41175.1 - 6.3e-07 28.6 40.0 0.0032 16.8 0.2 6.5 5 2 2 7 7 7 5 zinc-ribbon domain Nudix_N_2 PF14803.1 EKE41175.1 - 0.0023 17.5 28.8 0.74 9.5 0.1 6.1 4 2 1 5 5 5 4 Nudix N-terminal ORC6 PF05460.8 EKE41175.1 - 0.0047 16.0 13.1 0.0062 15.6 9.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Mitofilin PF09731.4 EKE41175.1 - 0.0061 15.2 3.2 0.0071 15.0 2.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein CDC27 PF09507.5 EKE41175.1 - 0.048 12.8 20.5 0.064 12.4 14.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YhfH PF14149.1 EKE41175.1 - 0.2 11.4 26.9 0.79 9.5 0.3 6.6 5 1 1 6 6 6 0 YhfH-like protein Neur_chan_memb PF02932.11 EKE41175.1 - 0.63 9.8 4.9 1.1 9.0 3.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 EKE41175.1 - 1.1 8.2 3.3 1.4 7.8 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-NADH-PPase PF09297.6 EKE41175.1 - 1.5 8.3 0.0 1.5 8.3 0.0 6.4 7 0 0 7 7 7 0 NADH pyrophosphatase zinc ribbon domain PolC_DP2 PF03833.8 EKE41175.1 - 4.4 4.8 23.6 0.48 8.0 6.7 2.5 1 1 2 3 3 3 0 DNA polymerase II large subunit DP2 zf-dskA_traR PF01258.12 EKE41175.1 - 5.1 6.9 29.6 2.2 8.0 0.2 6.5 6 2 0 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger UPF0547 PF10571.4 EKE41175.1 - 9.6 5.9 35.3 0.35 10.6 0.2 5.8 6 2 0 6 6 5 0 Uncharacterised protein family UPF0547 HMG_box PF00505.14 EKE41176.1 - 3.2e-10 40.1 2.9 3.2e-10 40.1 2.0 3.2 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE41176.1 - 7.3e-10 39.0 3.3 7.3e-10 39.0 2.3 3.0 2 1 1 3 3 3 1 HMG-box domain DUF4392 PF14336.1 EKE41176.1 - 0.0012 17.6 0.1 0.0014 17.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Cupin_5 PF06172.6 EKE41176.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Cupin superfamily (DUF985) Vac_ImportDeg PF09783.4 EKE41176.1 - 0.18 11.2 5.4 0.065 12.7 1.0 2.1 2 1 0 2 2 2 0 Vacuolar import and degradation protein PRP1_N PF06424.7 EKE41177.1 - 2.4 8.4 8.0 4.4 7.6 5.5 1.6 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Neurensin PF14927.1 EKE41178.1 - 0.0051 16.2 0.1 0.29 10.5 0.0 3.1 3 0 0 3 3 3 1 Neurensin UPF0104 PF03706.8 EKE41178.1 - 0.014 14.7 8.3 3.6 6.7 3.4 3.4 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0104) CbiQ PF02361.11 EKE41178.1 - 0.34 10.4 6.5 2.2 7.8 4.5 2.4 1 1 0 1 1 1 0 Cobalt transport protein E1-E2_ATPase PF00122.15 EKE41178.1 - 0.55 9.2 4.3 20 4.1 0.0 3.1 2 1 1 3 3 3 0 E1-E2 ATPase COX6C PF02937.10 EKE41178.1 - 1.2 9.0 4.6 4.1 7.3 0.1 3.7 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIc Treacle PF03546.9 EKE41179.1 - 0.01 14.6 0.3 0.011 14.6 0.2 1.0 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle DUF2672 PF10878.3 EKE41179.1 - 0.028 14.1 0.9 0.039 13.6 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2672) DUF1068 PF06364.7 EKE41179.1 - 0.04 13.5 0.4 0.042 13.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Glu_syn_central PF04898.9 EKE41179.1 - 0.1 11.8 0.5 0.11 11.7 0.3 1.0 1 0 0 1 1 1 0 Glutamate synthase central domain MCM PF00493.18 EKE41180.1 - 6.1e-122 406.5 0.0 9.2e-122 405.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKE41180.1 - 1.3e-16 61.1 2.3 4.2e-16 59.5 0.8 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKE41180.1 - 6.1e-09 35.3 0.1 1.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKE41180.1 - 3.6e-06 26.7 0.1 3.3e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKE41180.1 - 5.4e-05 22.8 0.0 0.00016 21.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKE41180.1 - 0.0026 17.2 0.0 0.05 13.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 EKE41180.1 - 0.014 15.7 0.3 0.054 13.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EKE41180.1 - 0.027 14.6 0.0 0.097 12.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Smr PF01713.16 EKE41181.1 - 4e-08 33.3 0.1 8.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Smr domain Scaffolding_pro PF11418.3 EKE41181.1 - 0.024 14.9 2.4 0.024 14.9 1.6 1.9 2 0 0 2 2 2 0 Phi29 scaffolding protein NAM-associated PF14303.1 EKE41181.1 - 0.38 11.0 10.7 0.63 10.3 7.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DRY_EERY PF09750.4 EKE41181.1 - 2.7 8.0 6.2 0.62 10.1 1.2 2.1 2 1 0 2 2 2 0 Alternative splicing regulator RhoGAP PF00620.22 EKE41182.1 - 1.1e-32 112.7 0.0 2.4e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EKE41182.1 - 7.1e-09 35.7 3.8 7.1e-09 35.7 2.6 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Pkinase PF00069.20 EKE41183.1 - 2.5e-40 138.2 0.1 4.3e-40 137.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41183.1 - 4.7e-24 84.8 0.0 6.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase InvH PF04741.7 EKE41184.1 - 0.045 13.6 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein RRM_1 PF00076.17 EKE41185.1 - 8.8e-11 41.2 0.5 5.1e-06 26.0 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41185.1 - 4.9e-10 39.2 0.1 0.00014 21.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41185.1 - 6.6e-10 38.6 0.1 1.1e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.1 EKE41186.1 - 2.8e-21 74.9 4.2 8.3e-13 47.7 0.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKE41186.1 - 3.7e-14 51.6 1.9 5e-05 22.7 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKE41186.1 - 1.1e-10 40.6 1.0 0.039 13.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41186.1 - 2.8e-09 36.4 1.3 4.9e-05 23.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41186.1 - 3.8e-09 36.9 0.0 0.00028 21.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41186.1 - 1.1e-06 27.9 1.8 0.013 15.2 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKE41186.1 - 9.8e-06 25.7 0.0 0.046 14.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EKE41186.1 - 0.00052 19.1 0.0 0.0012 17.9 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE41186.1 - 0.0088 16.3 0.2 0.5 10.7 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat CCAP PF11105.3 EKE41186.1 - 0.011 15.4 0.3 0.027 14.1 0.2 1.6 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a TPR_9 PF13371.1 EKE41186.1 - 0.013 15.3 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ChAPs PF09295.5 EKE41186.1 - 0.026 13.2 0.2 0.043 12.5 0.2 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 EKE41186.1 - 0.064 13.2 0.1 3 7.8 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 EKE41186.1 - 0.08 11.6 0.1 0.08 11.6 0.0 4.0 1 1 3 4 4 4 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EKE41186.1 - 0.25 11.9 1.7 1.6e+02 3.1 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Tash_PEST PF07708.6 EKE41186.1 - 0.71 9.8 5.6 1.6 8.7 3.9 1.7 1 0 0 1 1 1 0 Tash protein PEST motif OAD_gamma PF04277.8 EKE41186.1 - 0.89 9.9 8.2 11 6.4 1.3 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain IF4E PF01652.13 EKE41187.1 - 2.9e-30 104.9 1.3 3.4e-30 104.7 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E YcgR_2 PF12945.2 EKE41188.1 - 0.1 12.5 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein YcgR TFIIB PF00382.14 EKE41189.1 - 2.6e-26 91.2 0.0 3e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EKE41189.1 - 1.6e-09 37.8 7.9 1.6e-09 37.8 5.5 2.7 4 1 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EKE41189.1 - 4.3e-07 29.1 1.9 1.3e-06 27.6 1.3 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EKE41189.1 - 0.00097 18.5 2.8 0.0021 17.4 1.9 1.6 1 0 0 1 1 1 1 A2L zinc ribbon domain DUF2318 PF10080.4 EKE41189.1 - 0.0048 16.6 0.3 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.6 EKE41189.1 - 0.017 14.7 0.7 0.045 13.4 0.5 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Sigma70_r4 PF04545.11 EKE41189.1 - 0.022 14.0 0.6 0.51 9.6 0.1 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 GCC2_GCC3 PF07699.8 EKE41189.1 - 0.055 13.0 2.4 0.16 11.6 1.7 1.7 1 0 0 1 1 1 0 GCC2 and GCC3 RRN7 PF11781.3 EKE41189.1 - 0.082 12.4 1.6 0.18 11.3 0.6 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 LRR_4 PF12799.2 EKE41190.1 - 0.21 11.2 0.1 0.21 11.2 0.1 10.4 8 3 2 10 10 10 0 Leucine Rich repeats (2 copies) RhoGAP PF00620.22 EKE41191.1 - 4.6e-21 75.0 0.0 1.6e-20 73.2 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EKE41191.1 - 0.83 9.8 8.9 0.057 13.6 0.6 3.0 4 0 0 4 4 4 0 PH domain UBX PF00789.15 EKE41192.1 - 2.2e-19 69.2 0.2 9e-19 67.3 0.1 2.0 1 0 0 1 1 1 1 UBX domain Borrelia_P83 PF05262.6 EKE41192.1 - 0.064 11.5 21.3 0.089 11.0 14.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP70 PF00012.15 EKE41192.1 - 0.13 10.1 10.6 0.16 9.8 7.4 1.2 1 0 0 1 1 1 0 Hsp70 protein HAD_2 PF13419.1 EKE41192.1 - 0.36 11.0 2.2 0.78 9.9 1.6 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase U79_P34 PF03064.11 EKE41192.1 - 0.52 9.7 14.6 0.85 9.0 10.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Membralin PF09746.4 EKE41192.1 - 0.92 8.4 5.7 1.3 7.9 4.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein Asp-B-Hydro_N PF05279.6 EKE41192.1 - 1.4 8.7 22.0 2 8.2 15.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1682 PF07946.9 EKE41192.1 - 2.4 6.9 31.1 0.75 8.5 18.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1682) DUF1510 PF07423.6 EKE41192.1 - 3 7.1 21.2 4.9 6.4 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 EKE41192.1 - 7.3 6.4 12.4 12 5.7 8.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family APG5 PF04106.7 EKE41193.1 - 5e-28 97.9 1.0 5e-28 97.9 0.7 1.4 2 0 0 2 2 2 1 Autophagy protein Apg5 ABC_tran PF00005.22 EKE41194.1 - 2.6e-37 128.1 0.0 3.9e-17 62.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKE41194.1 - 2.3e-12 46.6 7.9 1.3e-06 27.8 0.3 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKE41194.1 - 4.8e-11 43.1 15.1 2.2e-05 24.6 1.4 4.6 4 2 1 5 5 3 3 AAA domain AAA_15 PF13175.1 EKE41194.1 - 2.6e-07 30.0 5.4 1.2 8.1 0.0 4.8 3 2 1 4 4 4 3 AAA ATPase domain Fer4 PF00037.22 EKE41194.1 - 8.7e-07 28.2 2.9 8.7e-07 28.2 2.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 EKE41194.1 - 1.6e-06 28.2 0.2 0.003 17.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain RLI PF04068.10 EKE41194.1 - 2.4e-06 27.0 4.0 2.4e-06 27.0 2.7 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA PF00004.24 EKE41194.1 - 4.5e-06 26.9 0.0 0.018 15.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE41194.1 - 1.3e-05 25.3 0.1 0.046 13.6 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EKE41194.1 - 1.4e-05 24.5 0.3 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EKE41194.1 - 5.2e-05 22.4 1.2 0.076 12.1 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKE41194.1 - 5.7e-05 23.9 3.3 0.39 11.5 0.1 3.5 3 2 0 3 3 3 2 AAA domain Fer4_21 PF14697.1 EKE41194.1 - 0.00011 22.0 11.2 0.001 18.8 6.7 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain Miro PF08477.8 EKE41194.1 - 0.00012 22.5 0.0 0.019 15.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 EKE41194.1 - 0.00022 20.7 0.0 0.4 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EKE41194.1 - 0.00036 20.3 0.0 0.67 9.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EKE41194.1 - 0.00038 19.9 0.4 0.31 10.4 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 EKE41194.1 - 0.00049 19.8 2.0 0.00049 19.8 1.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.17 EKE41194.1 - 0.00057 20.0 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase UPF0079 PF02367.12 EKE41194.1 - 0.00065 19.3 0.0 0.041 13.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 EKE41194.1 - 0.0008 18.2 0.1 0.0095 14.6 0.0 2.2 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EKE41194.1 - 0.001 18.7 0.5 0.41 10.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EKE41194.1 - 0.0014 18.6 0.1 0.68 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EKE41194.1 - 0.0015 18.4 1.6 0.84 9.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EKE41194.1 - 0.0017 18.0 0.3 1.2 8.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 EKE41194.1 - 0.0021 17.5 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E AAA_18 PF13238.1 EKE41194.1 - 0.004 17.4 7.5 0.85 9.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EKE41194.1 - 0.0043 16.9 0.1 0.37 10.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain G-alpha PF00503.15 EKE41194.1 - 0.0048 15.6 2.0 0.02 13.6 1.1 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.9 EKE41194.1 - 0.0053 16.4 0.2 0.8 9.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_10 PF13237.1 EKE41194.1 - 0.0069 16.1 2.6 0.0069 16.1 1.8 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EKE41194.1 - 0.0099 16.2 2.5 0.0099 16.2 1.8 2.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKE41194.1 - 0.01 16.1 2.8 0.01 16.1 1.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE41194.1 - 0.014 15.2 2.3 0.014 15.2 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Pox_J1 PF03338.10 EKE41194.1 - 0.026 14.2 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 Poxvirus J1 protein KaiC PF06745.8 EKE41194.1 - 0.029 13.4 0.2 0.074 12.1 0.1 1.7 1 0 0 1 1 1 0 KaiC Fer4_3 PF12798.2 EKE41194.1 - 0.029 14.9 4.2 0.029 14.9 2.9 2.5 2 1 0 2 2 1 0 4Fe-4S binding domain Septin PF00735.13 EKE41194.1 - 0.031 13.3 0.0 0.98 8.3 0.0 2.4 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.18 EKE41194.1 - 0.032 14.2 0.1 6.4 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EKE41194.1 - 0.048 13.2 0.3 0.81 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EKE41194.1 - 0.054 12.3 0.7 2.4 6.9 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EKE41194.1 - 0.077 12.6 5.1 1.2 8.7 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase Fer4_16 PF13484.1 EKE41194.1 - 0.083 13.6 0.7 0.083 13.6 0.5 3.0 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain FtsK_SpoIIIE PF01580.13 EKE41194.1 - 0.19 11.1 0.7 20 4.5 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EKE41194.1 - 0.2 11.4 0.2 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Fer4_11 PF13247.1 EKE41194.1 - 0.27 11.1 5.3 0.53 10.2 3.7 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.1 EKE41194.1 - 0.45 10.0 3.1 6.2 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain Fer4_8 PF13183.1 EKE41194.1 - 0.95 9.5 9.8 2.5 8.1 6.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EKE41194.1 - 1.2 9.7 6.0 0.27 11.8 0.9 2.4 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_4 PF12800.2 EKE41194.1 - 1.3 9.5 12.3 0.096 13.0 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Thymidylate_kin PF02223.12 EKE41194.1 - 2.1 7.7 6.7 8.8 5.6 0.0 3.5 4 0 0 4 4 2 0 Thymidylate kinase Peptidase_C1 PF00112.18 EKE41195.1 - 3.3e-14 53.2 0.1 6.3e-14 52.3 0.0 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE41195.1 - 0.00019 21.6 2.2 0.00028 21.0 1.5 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) CBM_4_9 PF02018.12 EKE41196.1 - 1.2e-06 28.5 1.0 3.7e-06 26.9 0.7 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain RasGAP PF00616.14 EKE41197.1 - 4.8e-09 36.1 8.4 4.8e-09 36.1 5.8 2.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF3987 PF13148.1 EKE41197.1 - 0.024 13.1 0.0 0.041 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RE_Eco47II PF09553.5 EKE41197.1 - 0.13 11.3 6.5 0.012 14.7 1.3 1.8 2 1 0 2 2 2 0 Eco47II restriction endonuclease DUF3231 PF11553.3 EKE41197.1 - 0.26 10.7 3.9 0.14 11.6 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3231) DUF241 PF03087.9 EKE41197.1 - 0.77 9.1 7.5 0.79 9.1 0.6 2.7 3 0 0 3 3 3 0 Arabidopsis protein of unknown function PMC2NT PF08066.7 EKE41197.1 - 0.87 9.9 4.3 0.33 11.2 0.3 2.3 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Metallophos PF00149.23 EKE41199.1 - 1.5e-43 148.5 0.0 1.9e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Acetyltransf_9 PF13527.1 EKE41200.1 - 2.8e-15 56.3 0.0 3.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKE41200.1 - 1.3e-09 37.9 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE41200.1 - 8.6e-09 35.4 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE41200.1 - 1.7e-06 28.1 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKE41200.1 - 0.00088 18.9 0.1 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKE41200.1 - 0.0075 16.4 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DNA_pol_B PF00136.16 EKE41203.1 - 3e-92 309.8 4.8 1.1e-71 242.0 2.4 2.8 1 1 0 2 2 2 2 DNA polymerase family B DUF1744 PF08490.7 EKE41203.1 - 0.0016 17.0 0.0 0.0032 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) eIF-5_eIF-2B PF01873.12 EKE41203.1 - 0.8 9.3 11.0 0.65 9.6 0.4 4.0 3 0 0 3 3 3 0 Domain found in IF2B/IF5 zf-C2H2 PF00096.21 EKE41203.1 - 1 9.8 8.2 42 4.7 0.1 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 EKE41203.1 - 1.4 8.9 13.9 0.68 9.9 4.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EKE41203.1 - 6.1 6.8 7.3 6.2 6.8 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger UQ_con PF00179.21 EKE41205.1 - 2.3e-18 65.9 0.0 6.8e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Consortin_C PF15281.1 EKE41205.1 - 0.067 12.6 0.3 0.18 11.3 0.2 1.7 1 0 0 1 1 1 0 Consortin C-terminus DUF3899 PF13038.1 EKE41205.1 - 0.098 12.8 0.5 0.098 12.8 0.3 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF3899) Auxin_canalis PF05703.6 EKE41205.1 - 0.61 9.8 7.4 0.96 9.2 5.2 1.3 1 0 0 1 1 1 0 Auxin canalisation Lipl32 PF12103.3 EKE41205.1 - 0.9 8.9 5.1 1.3 8.4 3.1 1.5 1 1 0 1 1 1 0 Surface lipoprotein of Spirochaetales order FAR1 PF03101.10 EKE41207.1 - 3.4e-09 37.1 3.4 6.4e-09 36.2 2.3 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EKE41207.1 - 3.6e-06 27.1 2.1 6.2e-06 26.3 0.6 2.1 2 0 0 2 2 2 1 Transcription factor AFT Arrestin_C PF02752.17 EKE41208.1 - 0.026 14.6 0.6 0.088 12.9 0.4 2.0 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Kinesin-related PF06548.6 EKE41211.1 - 0.18 10.3 2.8 4.3 5.7 0.7 2.0 1 1 1 2 2 2 0 Kinesin-related TTSSLRR PF12468.3 EKE41212.1 - 0.19 11.2 1.2 0.44 10.1 0.8 1.5 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Ank_5 PF13857.1 EKE41213.1 - 1.9e-11 43.8 0.1 8.4e-09 35.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE41213.1 - 2.5e-08 34.1 0.0 0.00041 20.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKE41213.1 - 7.5e-06 25.6 0.1 0.058 13.6 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 EKE41213.1 - 0.00032 20.3 0.3 0.046 13.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EKE41213.1 - 0.0099 16.3 0.1 3.4 8.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF3583 PF12126.3 EKE41213.1 - 0.089 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Pkinase PF00069.20 EKE41214.1 - 1.7e-68 230.5 0.0 2.4e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41214.1 - 1.5e-48 165.1 0.0 2.1e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41214.1 - 1.6e-08 33.9 0.0 2.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 EKE41214.1 - 1.8e-08 34.6 1.6 3.6e-08 33.6 0.2 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain DUF4099 PF13351.1 EKE41214.1 - 0.0098 15.7 0.2 0.036 13.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4099) APH PF01636.18 EKE41214.1 - 0.017 14.8 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EKE41214.1 - 0.028 13.2 0.1 0.07 11.9 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 DUF2499 PF10693.4 EKE41217.1 - 8.5 6.4 11.3 2.1 8.4 1.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2499) Ras PF00071.17 EKE41218.1 - 1.3e-54 183.9 0.4 1.6e-54 183.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41218.1 - 3.5e-17 62.9 0.3 7.3e-17 61.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE41218.1 - 5.7e-12 45.2 0.0 7.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41218.1 - 6.6e-06 25.6 0.3 0.00016 21.1 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE41218.1 - 0.00026 20.2 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE41218.1 - 0.0037 16.4 0.1 0.0078 15.4 0.0 1.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE41218.1 - 0.013 15.4 0.1 0.017 15.0 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 EKE41219.1 - 3.4e-54 182.5 0.0 4e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41219.1 - 2e-15 57.3 0.0 2.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41219.1 - 9.2e-07 28.2 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE41219.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE41219.1 - 0.021 14.2 0.0 0.073 12.4 0.0 1.7 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RRM_6 PF14259.1 EKE41220.1 - 6.7e-08 32.4 0.1 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE41220.1 - 8.6e-08 31.7 0.2 1.5e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41220.1 - 8.8e-07 28.6 0.1 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EKE41220.1 - 3e-05 23.7 3.7 5.1e-05 22.9 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EKE41220.1 - 0.00042 19.7 0.4 0.00075 18.9 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3978 PF13123.1 EKE41220.1 - 0.0022 17.3 0.9 0.0032 16.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3978) Cytochrome_C554 PF13435.1 EKE41220.1 - 0.0054 16.7 1.8 0.0054 16.7 1.2 1.7 1 1 0 1 1 1 1 Cytochrome c554 and c-prime RRM_3 PF08777.6 EKE41220.1 - 0.042 13.6 0.1 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif zf-CCHC_4 PF14392.1 EKE41220.1 - 0.19 11.4 2.7 0.34 10.6 1.0 2.1 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 EKE41220.1 - 0.47 10.2 5.6 1.4 8.6 3.9 1.9 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.9 EKE41220.1 - 0.65 7.9 12.9 0.7 7.8 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-5_eIF-2B PF01873.12 EKE41221.1 - 1e-37 128.5 2.5 1.5e-37 128.0 0.8 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 EKE41221.1 - 2.4e-09 37.0 0.7 2.4e-09 37.0 0.5 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Rota_NS53 PF00981.12 EKE41221.1 - 0.0086 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 Rotavirus RNA-binding Protein 53 (NS53) Elf1 PF05129.8 EKE41221.1 - 0.11 12.2 1.0 0.36 10.5 0.7 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PAP2_C PF14360.1 EKE41222.1 - 4.1e-08 33.3 12.3 4.1e-08 33.3 8.5 2.8 2 1 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EKE41222.1 - 0.06 13.0 14.5 0.032 13.9 7.2 2.4 2 1 0 2 2 2 0 PAP2 superfamily Myb_DNA-bind_6 PF13921.1 EKE41223.1 - 1.3e-25 89.2 2.1 3.8e-14 52.5 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKE41223.1 - 1.9e-25 88.6 2.0 1.6e-12 47.2 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain CG-1 PF03859.11 EKE41223.1 - 0.018 14.5 0.8 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 CG-1 domain PCI PF01399.22 EKE41224.1 - 0.00038 20.7 0.4 0.0011 19.2 0.1 1.9 2 0 0 2 2 2 1 PCI domain ArgK PF03308.11 EKE41225.1 - 6.3e-07 28.4 0.0 8.9e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 EKE41225.1 - 0.0015 18.2 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 EKE41225.1 - 0.0035 16.3 0.0 0.0062 15.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_17 PF13207.1 EKE41225.1 - 0.0075 17.0 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IIGP PF05049.8 EKE41225.1 - 0.012 14.5 0.2 0.021 13.6 0.2 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EKE41225.1 - 0.015 15.5 0.1 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 EKE41225.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 EKE41225.1 - 0.033 13.7 0.1 0.06 12.8 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EKE41225.1 - 0.037 13.9 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EKE41225.1 - 0.056 13.9 0.6 0.14 12.6 0.4 1.8 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EKE41225.1 - 0.084 12.8 0.5 0.19 11.6 0.3 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 EKE41225.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EKE41225.1 - 0.13 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EKE41225.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family A_thal_3526 PF09713.5 EKE41226.1 - 3e-05 24.0 0.2 5.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) DUF2459 PF09601.5 EKE41226.1 - 0.52 9.9 2.2 0.34 10.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Terminase_4 PF05119.7 EKE41226.1 - 5.8 7.1 6.0 6.8 6.9 0.5 2.7 1 1 2 3 3 3 0 Phage terminase, small subunit zf-UBR PF02207.15 EKE41227.1 - 8.2e-18 63.9 15.6 8.2e-18 63.9 10.8 4.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Adaptin_N PF01602.15 EKE41228.1 - 7.5e-76 255.5 18.6 8.5e-76 255.3 12.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EKE41228.1 - 1.1e-06 28.8 0.0 0.12 12.6 0.0 3.7 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EKE41228.1 - 1.8e-06 27.9 3.1 0.0061 16.4 0.1 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EKE41228.1 - 1.9e-06 27.4 0.5 0.28 11.3 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat DUF2435 PF10363.4 EKE41228.1 - 4.8e-06 26.3 4.2 0.019 14.8 0.1 4.2 4 1 1 5 5 5 2 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EKE41228.1 - 0.00016 21.0 0.6 0.03 13.6 0.0 3.0 2 1 1 3 3 3 1 CLASP N terminal DNA_alkylation PF08713.6 EKE41228.1 - 0.00063 19.3 0.0 0.68 9.4 0.0 3.7 2 2 0 3 3 3 1 DNA alkylation repair enzyme Cnd3 PF12719.2 EKE41228.1 - 0.0009 18.3 6.6 0.051 12.5 0.1 3.5 2 1 2 4 4 4 2 Nuclear condensing complex subunits, C-term domain DUF3861 PF12977.2 EKE41228.1 - 0.11 12.5 2.1 1.4 9.0 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) HEAT_EZ PF13513.1 EKE41228.1 - 0.22 12.0 5.8 17 6.0 0.1 4.0 3 1 1 4 4 4 0 HEAT-like repeat Arf PF00025.16 EKE41229.1 - 4.6e-47 159.4 0.1 5.1e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKE41229.1 - 1.1e-09 37.8 0.6 3.1e-09 36.3 0.4 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EKE41229.1 - 5.8e-09 35.5 0.1 6.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41229.1 - 8.5e-07 29.4 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKE41229.1 - 8.7e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EKE41229.1 - 0.0001 21.1 2.2 0.00011 21.0 0.4 1.6 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 EKE41229.1 - 0.003 17.0 0.0 0.0069 15.8 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE41229.1 - 0.015 15.2 0.9 0.14 12.1 0.6 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 EKE41229.1 - 0.066 12.6 0.9 2.4 7.5 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EKE41229.1 - 0.087 13.6 0.5 0.16 12.8 0.3 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EKE41229.1 - 0.15 11.7 0.2 15 5.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.20 EKE41230.1 - 7.1e-65 218.7 7.4 7.1e-65 218.7 5.1 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41230.1 - 1.2e-34 119.5 4.2 1.7e-34 119.0 2.9 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE41230.1 - 2.2e-05 23.6 1.0 3.2e-05 23.0 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.21 EKE41230.1 - 0.0046 17.0 0.5 0.023 14.8 0.1 2.4 2 0 0 2 2 2 1 FHA domain YrbL-PhoP_reg PF10707.4 EKE41230.1 - 0.021 14.1 0.2 0.021 14.1 0.2 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EKE41230.1 - 0.064 12.2 2.1 0.41 9.5 0.1 2.8 1 1 1 2 2 2 0 Kinase-like VWA_2 PF13519.1 EKE41231.1 - 2.9e-12 47.0 0.0 4.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE41231.1 - 7.7e-07 28.9 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain NifU_N PF01592.11 EKE41231.1 - 0.0075 16.2 0.1 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like N terminal domain Med25_VWA PF11265.3 EKE41231.1 - 0.1 11.6 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A DUF3006 PF11213.3 EKE41231.1 - 0.15 11.8 2.1 0.2 11.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3006) CRS1_YhbY PF01985.16 EKE41231.1 - 2 8.4 4.6 7.3 6.6 0.3 2.6 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain FH2 PF02181.18 EKE41232.1 - 5.9e-14 51.7 17.4 5.9e-14 51.7 12.1 3.2 2 2 1 3 3 3 1 Formin Homology 2 Domain DUF2968 PF11180.3 EKE41232.1 - 0.098 12.0 1.2 0.29 10.4 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TSKS PF15358.1 EKE41232.1 - 0.27 9.3 7.5 0.41 8.7 5.2 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF3450 PF11932.3 EKE41232.1 - 0.82 8.8 11.0 0.079 12.2 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 EKE41232.1 - 0.84 8.7 5.3 3.6 6.6 0.7 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Chordopox_L2 PF05803.7 EKE41232.1 - 1.7 8.3 11.2 0.75 9.4 0.2 3.3 3 0 0 3 3 3 0 Chordopoxvirus L2 protein SSFA2_C PF14723.1 EKE41232.1 - 2.7 7.6 8.0 1.3 8.7 3.0 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus CinA PF02464.12 EKE41233.1 - 7.3e-47 158.6 0.2 9e-47 158.3 0.2 1.0 1 0 0 1 1 1 1 Competence-damaged protein adh_short_C2 PF13561.1 EKE41233.1 - 0.082 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PTCB-BRCT PF12738.2 EKE41234.1 - 1.6e-17 63.1 0.0 1.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKE41234.1 - 1.4e-10 41.1 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_alkylation PF08713.6 EKE41235.1 - 7.6e-24 84.4 0.0 1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme HMG_box PF00505.14 EKE41236.1 - 1.1e-13 51.1 1.5 1.7e-13 50.6 1.1 1.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE41236.1 - 4.9e-07 30.0 2.4 7.5e-07 29.4 1.6 1.3 1 0 0 1 1 1 1 HMG-box domain DUF1018 PF06252.7 EKE41236.1 - 0.092 13.2 0.4 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) LRR_4 PF12799.2 EKE41237.1 - 9.9e-57 187.8 81.0 2e-08 33.6 1.2 12.5 11 2 2 14 14 14 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE41237.1 - 7.1e-45 150.5 68.1 7.2e-10 38.4 3.2 10.0 4 2 6 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 EKE41237.1 - 2e-23 78.8 65.7 0.033 14.1 0.1 20.3 20 1 1 21 21 21 10 Leucine Rich Repeat LRR_7 PF13504.1 EKE41237.1 - 2.2e-19 66.0 35.7 0.8 10.1 0.0 17.6 19 1 0 19 19 19 6 Leucine rich repeat PP2C PF00481.16 EKE41237.1 - 2.8e-19 69.5 0.1 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.1 EKE41237.1 - 2e-10 39.6 67.9 0.11 12.6 0.1 16.6 18 1 1 19 19 19 8 Leucine Rich repeat LRR_9 PF14580.1 EKE41237.1 - 3.3e-05 23.5 24.7 0.0077 15.8 0.6 6.1 3 3 4 7 7 7 5 Leucine-rich repeat RNase_HII PF01351.13 EKE41240.1 - 4.7e-42 143.8 0.0 5.6e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII bZIP_1 PF00170.16 EKE41241.1 - 0.0025 17.7 4.3 0.0025 17.7 3.0 10.3 7 3 5 12 12 12 5 bZIP transcription factor DivIC PF04977.10 EKE41241.1 - 0.017 14.6 5.2 0.017 14.6 3.6 10.8 3 3 8 11 11 11 0 Septum formation initiator Med31 PF05669.7 EKE41242.1 - 3.1e-33 113.5 8.1 3.9e-33 113.2 5.6 1.1 1 0 0 1 1 1 1 SOH1 Mif2_N PF15624.1 EKE41243.1 - 0.047 14.2 1.0 0.06 13.9 0.7 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF4225 PF13988.1 EKE41244.1 - 0.0065 15.9 0.2 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4225) FtsK_SpoIIIE PF01580.13 EKE41246.1 - 0.0053 16.2 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Ribosomal_L25p PF01386.14 EKE41246.1 - 0.026 14.6 0.1 0.084 13.0 0.1 1.8 1 1 0 2 2 2 0 Ribosomal L25p family ATP-gua_PtransN PF02807.10 EKE41246.1 - 0.086 13.0 0.2 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain Sec23_trunk PF04811.10 EKE41248.1 - 1.3e-34 119.6 0.1 2.1e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 EKE41248.1 - 4.4e-14 51.7 2.0 9.7e-14 50.6 1.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EKE41248.1 - 9.3e-11 42.0 0.0 3.3e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EKE41248.1 - 4.1e-10 39.0 0.1 1.4e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EKE41248.1 - 0.00074 19.1 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Lipase_3 PF01764.20 EKE41249.1 - 3.6e-24 84.9 0.1 9.7e-24 83.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 EKE41249.1 - 0.0033 17.0 0.0 0.0033 17.0 0.0 2.1 2 1 0 2 2 2 1 PGAP1-like protein CAMSAP_CKK PF08683.6 EKE41249.1 - 0.054 13.1 0.7 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated PUF PF00806.14 EKE41250.1 - 4.1e-07 29.1 5.6 0.016 14.6 0.1 5.0 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat CPL PF08144.6 EKE41250.1 - 1e-05 25.4 0.6 0.00081 19.2 0.0 3.6 3 1 0 3 3 3 1 CPL (NUC119) domain Cullin_binding PF03556.10 EKE41250.1 - 0.032 14.3 0.9 0.18 11.9 0.1 2.4 2 0 0 2 2 2 0 Cullin binding Porin_3 PF01459.17 EKE41251.1 - 6.3e-09 35.5 0.0 8.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic porin BRCT PF00533.21 EKE41252.1 - 5.9e-07 29.5 0.4 0.029 14.5 0.0 3.2 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PQQ_3 PF13570.1 EKE41252.1 - 0.0012 19.0 0.0 3.7 7.9 0.0 4.3 4 0 0 4 4 4 1 PQQ-like domain WD40 PF00400.27 EKE41252.1 - 0.031 14.1 0.5 21 5.1 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Pkinase PF00069.20 EKE41253.1 - 1.1e-66 224.6 0.1 1.5e-66 224.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41253.1 - 6e-33 114.0 0.1 7.8e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE41253.1 - 5.5e-17 61.8 0.3 1.2e-16 60.8 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKE41253.1 - 4e-08 33.4 1.0 4.1e-07 30.2 0.7 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EKE41253.1 - 8e-06 25.8 0.2 1.6e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EKE41253.1 - 3.4e-05 23.6 0.1 7.7e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EKE41253.1 - 0.00014 20.9 0.1 0.014 14.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PH_9 PF15410.1 EKE41253.1 - 0.0081 16.3 0.7 0.036 14.2 0.1 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain HSP20 PF00011.16 EKE41254.1 - 2.2e-17 62.7 0.0 2.7e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pro_isomerase PF00160.16 EKE41255.1 - 7.3e-51 172.4 0.5 8.1e-51 172.2 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 EKE41255.1 - 0.086 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Pkinase PF00069.20 EKE41256.1 - 2.6e-103 344.7 1.8 7.6e-57 192.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41256.1 - 3.9e-65 219.4 1.1 9.9e-36 123.1 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EKE41256.1 - 2.7e-06 26.5 0.0 0.055 12.4 0.0 2.9 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 EKE41256.1 - 0.0027 17.0 2.3 1.1 8.6 0.1 2.5 2 0 0 2 2 2 2 RIO1 family AAA_22 PF13401.1 EKE41256.1 - 0.11 12.5 0.1 0.59 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain TLD PF07534.11 EKE41257.1 - 3.9e-06 26.9 0.6 5.6e-06 26.3 0.4 1.4 1 1 0 1 1 1 1 TLD DUF3870 PF12986.2 EKE41257.1 - 0.023 14.9 0.4 0.05 13.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Nicastrin PF05450.10 EKE41258.1 - 6e-07 28.9 0.4 1.1e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Nicastrin Peptidase_M28 PF04389.12 EKE41258.1 - 2.4e-05 24.1 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PCI PF01399.22 EKE41259.1 - 0.0057 16.9 2.7 0.072 13.4 0.1 2.7 2 0 0 2 2 2 1 PCI domain Sulfolobus_pRN PF05584.6 EKE41259.1 - 0.021 14.7 0.2 0.067 13.1 0.0 1.9 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein MarR_2 PF12802.2 EKE41259.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 MarR family TPR_2 PF07719.12 EKE41259.1 - 0.088 12.7 2.4 0.74 9.8 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.15 EKE41260.1 - 4.4e-38 130.1 4.3 5.4e-38 129.9 3.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 EKE41260.1 - 0.00063 19.7 0.8 0.00077 19.4 0.5 1.4 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 DUF3784 PF12650.2 EKE41260.1 - 0.029 14.2 0.3 0.049 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) FliG_N PF14842.1 EKE41260.1 - 0.055 13.5 0.1 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 FliG N-terminal domain Catalase-rel PF06628.7 EKE41260.1 - 0.13 12.1 0.3 6.7 6.6 0.0 2.8 3 0 0 3 3 3 0 Catalase-related immune-responsive MFS_1 PF07690.11 EKE41261.1 - 2.4e-12 46.2 34.7 1.1e-11 44.0 19.6 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily Pex24p PF06398.6 EKE41261.1 - 0.61 8.8 3.8 0.83 8.3 1.7 2.0 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DNA_primase_S PF01896.14 EKE41262.1 - 4.6e-45 152.9 0.4 8.9e-45 152.0 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Adaptin_N PF01602.15 EKE41264.1 - 5.4e-54 183.4 16.9 5.4e-54 183.4 11.7 1.9 1 1 1 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EKE41264.1 - 1.7e-47 160.4 0.2 4.7e-47 158.9 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EKE41264.1 - 8.2e-45 151.9 0.2 8.2e-45 151.9 0.2 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EKE41264.1 - 1e-07 32.1 0.0 2.5e-05 24.4 0.0 3.8 3 2 1 4 4 4 1 HEAT repeats HEAT PF02985.17 EKE41264.1 - 0.00026 20.7 0.0 0.018 15.0 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat RPAP3_C PF13877.1 EKE41264.1 - 0.0042 17.0 0.3 0.23 11.4 0.0 3.8 4 0 0 4 4 4 1 Potential Monad-binding region of RPAP3 MIT PF04212.13 EKE41264.1 - 0.0051 16.6 0.3 0.47 10.3 0.1 3.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain DNA_alkylation PF08713.6 EKE41264.1 - 0.0079 15.7 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 DNA alkylation repair enzyme Arm PF00514.18 EKE41264.1 - 0.089 12.6 0.2 11 5.9 0.0 4.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF2332 PF10094.4 EKE41264.1 - 0.11 11.4 0.0 0.39 9.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2332) Catalase-rel PF06628.7 EKE41264.1 - 0.11 12.3 0.3 8.6 6.3 0.0 3.3 3 0 0 3 3 3 0 Catalase-related immune-responsive RNA_pol_Rpb6 PF01192.17 EKE41265.1 - 4.3e-18 64.7 0.1 6.5e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 UQ_con PF00179.21 EKE41266.1 - 3.1e-51 172.4 0.0 3.5e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKE41266.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKE41266.1 - 0.042 13.7 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EKE41266.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain RasGEF PF00617.14 EKE41267.1 - 3e-15 56.4 0.3 7.5e-15 55.1 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE41267.1 - 2.1e-05 24.5 5.6 0.00013 22.0 2.6 2.9 2 1 0 2 2 2 1 RasGEF N-terminal motif SWIB PF02201.13 EKE41267.1 - 0.026 14.2 0.0 0.084 12.5 0.0 1.8 1 0 0 1 1 1 0 SWIB/MDM2 domain AMP-binding PF00501.23 EKE41268.1 - 1.6e-19 69.6 0.0 9.2e-19 67.1 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme DUF2992 PF11208.3 EKE41268.1 - 0.063 13.1 22.9 0.18 11.6 15.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF1682 PF07946.9 EKE41268.1 - 2 7.2 21.6 5.7 5.6 14.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ABC_membrane PF00664.18 EKE41269.1 - 2.4e-44 151.7 17.0 3.2e-44 151.4 11.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EKE41269.1 - 6.7e-14 52.3 0.1 1.3e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EKE41269.1 - 0.0019 17.6 0.1 0.0047 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EKE41269.1 - 0.0031 16.6 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 EKE41269.1 - 0.0065 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE41269.1 - 0.0098 15.8 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EKE41269.1 - 0.013 16.2 0.0 0.06 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EKE41269.1 - 0.038 12.6 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein G-alpha PF00503.15 EKE41269.1 - 0.049 12.3 0.1 0.079 11.6 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.17 EKE41269.1 - 0.099 11.4 0.2 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 EKE41269.1 - 0.11 11.9 0.1 0.36 10.2 0.1 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EKE41269.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EKE41269.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UBA PF00627.26 EKE41271.1 - 2.8e-20 71.5 0.6 9.1e-09 34.9 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EKE41271.1 - 1.5e-11 43.5 0.4 2.6e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 EKE41271.1 - 4.9e-05 22.6 0.3 0.00013 21.4 0.2 1.7 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 EKE41271.1 - 0.00017 21.1 0.3 0.00037 20.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EKE41271.1 - 0.0033 16.9 0.0 0.062 12.9 0.0 2.6 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain DUF2407 PF10302.4 EKE41271.1 - 0.015 15.4 0.3 0.066 13.4 0.0 2.1 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF2464 PF10240.4 EKE41271.1 - 0.44 9.8 2.9 0.14 11.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2464) DPBB_1 PF03330.13 EKE41272.1 - 0.0073 16.2 0.5 0.43 10.5 0.1 3.3 3 0 0 3 3 3 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel VCBS PF13517.1 EKE41273.1 - 3e-22 78.7 4.8 7.7e-13 48.5 0.1 4.9 4 1 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EKE41273.1 - 3.3e-08 32.9 0.1 1.7 8.4 0.0 5.2 5 0 0 5 5 5 3 FG-GAP repeat Ribosomal_L36e PF01158.13 EKE41273.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L36e TcdB_toxin_midN PF12256.3 EKE41273.1 - 0.028 13.8 0.4 0.88 8.9 0.0 3.0 1 1 2 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region CKS PF01111.14 EKE41274.1 - 5.8e-36 122.1 0.9 6.4e-36 122.0 0.7 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SH3_4 PF06347.8 EKE41274.1 - 0.082 12.4 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Git3_C PF11970.3 EKE41275.1 - 4.9e-08 32.6 6.0 4.9e-08 32.6 4.1 3.6 3 2 1 4 4 4 1 G protein-coupled glucose receptor regulating Gpa2 C-term zf-AN1 PF01428.11 EKE41276.1 - 5.6e-07 29.3 39.9 1.6e-05 24.6 10.2 3.6 3 1 1 4 4 4 2 AN1-like Zinc finger Tic22 PF04278.7 EKE41277.1 - 0.069 12.3 0.1 0.086 12.0 0.1 1.1 1 0 0 1 1 1 0 Tic22-like family Arm PF00514.18 EKE41278.1 - 1.2e-12 47.1 0.0 0.0016 18.1 0.0 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EKE41278.1 - 7.9e-05 22.4 0.7 5.2 7.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EKE41278.1 - 0.0001 22.5 0.0 1.6 9.1 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats IBB PF01749.15 EKE41278.1 - 0.00051 20.1 1.1 0.00098 19.2 0.8 1.4 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.1 EKE41278.1 - 0.01 15.7 2.7 0.93 9.4 0.0 2.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Glyco_hydro_79n PF03662.9 EKE41278.1 - 0.02 13.5 0.0 0.034 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain DUF1430 PF07242.6 EKE41279.1 - 0.034 14.2 0.5 0.05 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) GLE1 PF07817.8 EKE41279.1 - 0.043 12.7 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 GLE1-like protein DUF912 PF06024.7 EKE41279.1 - 0.098 12.7 1.9 0.15 12.1 1.3 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ERCC4 PF02732.10 EKE41279.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 ERCC4 domain Synaptobrevin PF00957.16 EKE41279.1 - 2.1 7.9 14.0 1.1 8.9 0.4 3.0 1 1 2 3 3 3 0 Synaptobrevin Baculo_11_kDa PF06143.6 EKE41279.1 - 2.6 7.4 4.6 0.84 9.0 1.1 1.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family P5-ATPase PF12409.3 EKE41279.1 - 4.7 7.0 6.2 8.8 6.2 0.1 2.1 1 1 1 2 2 2 0 P5-type ATPase cation transporter ENTH PF01417.15 EKE41280.1 - 1.9e-27 95.5 0.0 4.2e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EKE41280.1 - 6.5e-05 21.7 0.2 9.8e-05 21.1 0.1 1.3 1 0 0 1 1 1 1 ANTH domain cwf21 PF08312.7 EKE41280.1 - 5.6 6.8 6.5 8.2 6.3 0.2 2.5 2 1 0 2 2 2 0 cwf21 domain WD40 PF00400.27 EKE41281.1 - 0.0082 15.9 18.0 0.12 12.3 0.0 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF2750 PF11042.3 EKE41281.1 - 0.051 13.6 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2750) Pkinase_Tyr PF07714.12 EKE41282.1 - 2e-53 181.1 0.0 3.7e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41282.1 - 2.1e-47 161.4 0.0 3.8e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EKE41282.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSP70 PF00012.15 EKE41284.1 - 4.6e-05 21.5 0.1 5.1e-05 21.3 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein Chromo PF00385.19 EKE41287.1 - 3.8e-07 29.6 0.1 0.0027 17.3 0.0 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain LRR_5 PF13306.1 EKE41288.1 - 5.5e-43 145.7 14.7 6.6e-43 145.5 10.2 1.1 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41288.1 - 1.3e-21 76.1 0.1 9.7e-08 31.6 0.1 3.1 1 1 2 3 3 3 3 Leucine rich repeat zf-Tim10_DDP PF02953.10 EKE41288.1 - 0.19 11.0 15.3 4.1 6.7 1.2 4.8 2 1 3 5 5 5 0 Tim10/DDP family zinc finger Resistin PF06954.6 EKE41288.1 - 0.42 10.9 9.3 3 8.1 0.2 2.9 1 1 2 3 3 3 0 Resistin Pkinase PF00069.20 EKE41289.1 - 4.2e-26 91.6 0.2 1.6e-25 89.7 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41289.1 - 4.2e-13 48.9 0.0 1e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE41289.1 - 4.4e-09 36.4 1.1 1.1e-08 35.1 0.7 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKE41289.1 - 9.3e-08 32.3 2.4 9.3e-08 32.3 1.7 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EKE41289.1 - 3e-06 27.0 1.4 3e-06 27.0 1.0 1.7 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 EKE41289.1 - 5.1e-06 26.4 0.9 1.3e-05 25.2 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Flavi_NS1 PF00948.16 EKE41289.1 - 0.054 11.9 0.1 0.089 11.1 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Actin PF00022.14 EKE41291.1 - 5.8e-99 331.1 0.0 6.6e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKE41291.1 - 0.0011 17.6 0.2 0.016 13.8 0.1 2.2 1 1 0 1 1 1 1 MreB/Mbl protein LRR_4 PF12799.2 EKE41293.1 - 5e-05 22.8 15.8 0.0016 18.0 0.1 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE41293.1 - 0.0009 18.9 10.2 0.14 11.9 1.3 3.2 1 1 3 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EKE41293.1 - 0.0024 17.6 10.3 4.4 7.7 0.2 5.1 3 2 1 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EKE41293.1 - 0.01 15.8 5.4 3.7 8.1 0.0 4.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EKE41293.1 - 0.028 14.4 13.1 86 3.6 5.7 4.8 3 1 0 3 3 3 0 Leucine Rich repeat Ras PF00071.17 EKE41294.1 - 5.4e-51 172.1 0.0 6.2e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41294.1 - 7.2e-13 49.0 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41294.1 - 4e-12 45.7 0.0 5.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE41294.1 - 2.8e-06 26.6 0.0 3.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE41294.1 - 0.005 16.3 0.1 0.044 13.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKE41294.1 - 0.058 12.8 0.3 0.89 9.0 0.2 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation HTH_34 PF13601.1 EKE41294.1 - 0.095 12.7 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain MMR_HSR1 PF01926.18 EKE41294.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RhoGAP PF00620.22 EKE41295.1 - 2.2e-20 72.7 1.1 3.9e-20 72.0 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EKE41295.1 - 0.19 11.9 1.3 1.5 9.0 0.9 2.7 1 1 0 1 1 1 0 PH domain DcpS_C PF11969.3 EKE41295.1 - 0.48 10.6 3.2 1 9.6 0.0 2.5 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding SNARE PF05739.14 EKE41296.1 - 6.4e-13 48.1 5.0 8.5e-13 47.7 3.5 1.2 1 0 0 1 1 1 1 SNARE domain Rifin_STEVOR PF02009.11 EKE41296.1 - 0.0011 18.7 2.2 0.0011 18.6 1.5 1.0 1 0 0 1 1 1 1 Rifin/stevor family Ran-binding PF05508.6 EKE41296.1 - 0.014 14.3 4.9 0.016 14.1 3.4 1.0 1 0 0 1 1 1 0 RanGTP-binding protein Rhabdo_glycop PF00974.13 EKE41296.1 - 0.026 12.7 0.6 0.029 12.6 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Spc7 PF08317.6 EKE41296.1 - 0.039 12.6 5.1 0.041 12.5 3.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.7 EKE41296.1 - 0.056 13.2 4.0 0.082 12.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) S_layer_N PF05123.7 EKE41296.1 - 0.081 12.5 2.9 0.098 12.2 2.0 1.0 1 0 0 1 1 1 0 S-layer like family, N-terminal region Atg14 PF10186.4 EKE41296.1 - 0.11 11.4 3.7 0.13 11.2 2.6 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APC_15aa PF05972.6 EKE41296.1 - 0.12 12.3 0.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 APC 15 residue motif Sec20 PF03908.8 EKE41296.1 - 0.14 11.9 1.5 0.21 11.3 0.7 1.5 1 1 0 1 1 1 0 Sec20 Cortexin PF11057.3 EKE41296.1 - 0.15 11.6 0.6 0.21 11.2 0.3 1.4 1 1 0 1 1 1 0 Cortexin of kidney Syntaxin PF00804.20 EKE41296.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.2 1 1 1 2 2 2 0 Syntaxin RasGAP_C PF03836.10 EKE41296.1 - 0.23 11.1 4.9 0.33 10.6 3.4 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Synaptobrevin PF00957.16 EKE41296.1 - 1.2 8.7 10.3 0.89 9.2 6.0 1.7 2 1 0 2 2 2 0 Synaptobrevin TMEM154 PF15102.1 EKE41296.1 - 1.2 8.7 7.6 4.9 6.8 5.3 2.0 1 1 0 1 1 1 0 TMEM154 protein family Fib_alpha PF08702.5 EKE41296.1 - 2.5 8.2 8.2 8.5 6.4 5.5 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF912 PF06024.7 EKE41296.1 - 3.2 7.8 9.7 19 5.3 6.8 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Na_H_Exchanger PF00999.16 EKE41297.1 - 0.0078 14.7 0.8 0.01 14.3 0.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2306 PF10067.4 EKE41297.1 - 0.023 14.8 6.0 0.032 14.3 1.8 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) MnhB PF04039.8 EKE41297.1 - 0.075 13.0 4.8 0.071 13.1 1.8 1.8 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Peptidase_U4 PF03419.8 EKE41297.1 - 0.1 11.6 17.6 0.58 9.1 7.9 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Zip PF02535.17 EKE41297.1 - 0.34 9.8 4.0 0.97 8.3 0.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter CD34_antigen PF06365.7 EKE41297.1 - 1.6 8.3 5.9 8.2 6.0 0.5 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF3487 PF11990.3 EKE41297.1 - 1.6 8.1 4.8 1.7 8.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Vma12 PF11712.3 EKE41297.1 - 2.2 7.9 9.9 7.6 6.2 0.6 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF912 PF06024.7 EKE41297.1 - 5.4 7.1 10.5 0.98 9.5 1.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Lipase_3 PF01764.20 EKE41298.1 - 1.1e-18 67.2 0.0 2.6e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EKE41298.1 - 0.054 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE41298.1 - 0.056 13.1 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EKE41298.1 - 0.062 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF148 PF02520.12 EKE41298.1 - 0.087 12.6 0.9 0.31 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 RHD3 PF05879.7 EKE41299.1 - 2.3e-150 501.9 12.6 3e-150 501.5 8.7 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 EKE41299.1 - 3e-05 23.9 0.0 8.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKE41299.1 - 0.00059 19.6 0.0 0.0025 17.6 0.0 2.1 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 EKE41299.1 - 0.003 17.5 0.7 0.006 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EKE41299.1 - 0.0037 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein His_Phos_2 PF00328.17 EKE41299.1 - 0.034 13.4 2.6 0.29 10.3 1.8 2.5 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) YpjP PF14005.1 EKE41299.1 - 4.9 6.9 9.1 2.9 7.6 0.5 3.3 2 1 1 3 3 3 0 YpjP-like protein GNAT_acetyltr_2 PF13718.1 EKE41300.1 - 7.9e-70 234.1 0.0 2.5e-69 232.5 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EKE41300.1 - 1.3e-61 207.2 2.9 1.3e-61 207.2 0.0 2.6 4 0 0 4 4 4 1 Helicase DUF1726 PF08351.6 EKE41300.1 - 6.6e-35 118.6 0.8 6.5e-34 115.4 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EKE41300.1 - 2.8e-18 65.8 0.4 2.8e-18 65.8 0.3 2.2 3 0 0 3 3 3 1 Possible tRNA binding domain DEAD PF00270.24 EKE41300.1 - 0.0023 17.4 0.5 0.0071 15.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Acetyltransf_7 PF13508.1 EKE41300.1 - 0.04 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Flavodoxin_4 PF12682.2 EKE41301.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin TFIIA PF03153.8 EKE41302.1 - 8.3e-16 58.8 6.4 4.4e-11 43.2 0.1 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.23 EKE41303.1 - 3.7e-07 29.7 0.6 3.7e-07 29.7 0.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF373 PF04123.8 EKE41304.1 - 0.011 14.8 2.5 0.015 14.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MARVEL PF01284.18 EKE41304.1 - 0.46 10.2 7.3 0.12 12.2 1.3 2.1 2 1 0 2 2 2 0 Membrane-associating domain Transmemb_17 PF09799.4 EKE41304.1 - 6.3 7.1 11.3 0.62 10.4 4.5 1.7 2 0 0 2 2 2 0 Predicted membrane protein PRT_C PF08372.5 EKE41305.1 - 0.013 15.0 0.1 0.013 15.0 0.1 1.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DASH_Dad1 PF08649.5 EKE41305.1 - 0.84 9.3 4.6 2.8 7.6 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad1 Helicase_C PF00271.26 EKE41307.1 - 3e-21 75.0 0.0 1.4e-20 72.8 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE41307.1 - 3.4e-20 72.2 0.1 2.5e-19 69.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.5 EKE41307.1 - 2.6e-07 30.3 0.8 2.6e-07 30.3 0.5 2.5 2 0 0 2 2 2 1 RQC domain HRDC PF00570.18 EKE41307.1 - 6.6e-05 22.5 0.6 6.6e-05 22.5 0.4 3.0 3 1 0 3 3 3 1 HRDC domain Thioredoxin PF00085.15 EKE41309.1 - 6.1e-13 48.3 0.0 9.9e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE41309.1 - 2e-05 24.7 0.8 6.1e-05 23.1 0.6 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKE41309.1 - 0.0018 18.3 0.6 0.005 16.9 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EKE41309.1 - 0.0027 17.7 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EKE41309.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 EKE41309.1 - 0.059 13.3 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_4 PF13462.1 EKE41309.1 - 0.062 13.3 1.0 0.15 12.0 0.2 2.0 2 1 0 2 2 2 0 Thioredoxin D5_N PF08706.6 EKE41309.1 - 0.077 13.0 0.2 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 D5 N terminal like AhpC-TSA PF00578.16 EKE41309.1 - 0.083 12.5 0.2 0.19 11.3 0.1 1.6 1 1 0 1 1 1 0 AhpC/TSA family DUF3080 PF11279.3 EKE41310.1 - 0.0052 15.9 5.6 0.0052 15.9 3.9 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3080) NADPH_Ox PF08414.5 EKE41310.1 - 0.0084 16.1 1.0 0.018 15.1 0.2 1.8 1 1 1 2 2 2 1 Respiratory burst NADPH oxidase DUF1217 PF06748.7 EKE41310.1 - 0.063 13.3 1.6 0.15 12.1 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) NAAA-beta PF15508.1 EKE41310.1 - 0.2 12.0 4.8 1.2 9.5 0.2 2.8 1 1 2 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Phasin PF05597.6 EKE41310.1 - 0.5 10.1 5.1 0.39 10.4 2.3 1.7 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMP_2 PF06791.8 EKE41310.1 - 0.68 9.5 5.0 0.31 10.6 0.7 2.0 1 1 0 2 2 2 0 Prophage tail length tape measure protein Sds3 PF08598.6 EKE41310.1 - 1 8.8 12.9 1.7 8.1 8.9 1.4 1 1 0 1 1 1 0 Sds3-like EAP30 PF04157.11 EKE41310.1 - 1.2 8.2 11.4 1.2 8.2 0.7 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family DUF948 PF06103.6 EKE41310.1 - 1.8 8.4 13.8 0.66 9.8 2.8 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Hemocyanin_N PF03722.9 EKE41310.1 - 1.8 8.6 11.8 4.2 7.5 4.7 2.8 2 1 0 2 2 2 0 Hemocyanin, all-alpha domain Ribosomal_S30AE PF02482.14 EKE41310.1 - 1.9 8.9 6.4 0.73 10.3 1.3 2.1 1 1 1 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF4570 PF15134.1 EKE41310.1 - 3.3 7.5 7.2 0.55 10.0 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) PMC2NT PF08066.7 EKE41310.1 - 4.9 7.5 8.2 2.9 8.2 1.5 2.7 1 1 2 3 3 3 0 PMC2NT (NUC016) domain KapB PF08810.5 EKE41310.1 - 5 7.1 8.0 1 9.4 0.6 2.5 1 1 2 3 3 3 0 Kinase associated protein B DUF4319 PF14203.1 EKE41310.1 - 6.5 6.3 9.0 4.6 6.8 0.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4319) CLAMP PF14769.1 EKE41310.1 - 7.5 6.7 7.4 2.1 8.5 1.3 2.2 1 1 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 RtcB PF01139.12 EKE41311.1 - 2.1e-140 468.4 0.1 2.3e-140 468.3 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB WD40 PF00400.27 EKE41312.1 - 1e-06 28.3 0.0 0.04 13.8 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Vps16_N PF04841.8 EKE41312.1 - 0.00024 19.7 3.7 0.00055 18.5 0.1 2.4 2 1 1 3 3 3 1 Vps16, N-terminal region Lgl_C PF08596.5 EKE41312.1 - 0.0068 14.9 0.2 0.0068 14.9 0.1 2.8 1 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal Utp14 PF04615.8 EKE41312.1 - 0.41 8.7 27.7 0.56 8.3 19.2 1.0 1 0 0 1 1 1 0 Utp14 protein DUF106 PF01956.11 EKE41312.1 - 7 6.1 12.8 0.079 12.4 1.0 2.2 1 1 1 2 2 2 0 Integral membrane protein DUF106 Asp-B-Hydro_N PF05279.6 EKE41312.1 - 9.2 6.0 29.7 13 5.5 20.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DnaJ-X PF14308.1 EKE41314.1 - 0.044 13.0 2.4 0.082 12.1 1.6 1.5 1 1 0 1 1 1 0 X-domain of DnaJ-containing SlyX PF04102.7 EKE41314.1 - 0.12 12.7 1.4 0.32 11.4 1.0 1.7 1 0 0 1 1 1 0 SlyX DUF3091 PF11291.3 EKE41314.1 - 0.41 10.6 6.5 0.19 11.6 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) NPV_P10 PF05531.7 EKE41314.1 - 1.1 9.5 4.7 1.3 9.3 1.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Myb_DNA-binding PF00249.26 EKE41315.1 - 9.8e-22 76.7 2.7 8.6e-10 38.5 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE41315.1 - 5.1e-21 74.5 5.1 1.3e-13 50.8 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain KSR1-SAM PF13543.1 EKE41315.1 - 0.0032 17.2 0.0 0.0059 16.3 0.0 1.4 1 1 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Myb_DNA-bind_4 PF13837.1 EKE41315.1 - 1.4 9.1 10.6 6.7 6.9 0.4 3.8 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain zf-met PF12874.2 EKE41316.1 - 1e-05 25.5 0.6 1.7e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EKE41316.1 - 5.5e-05 23.1 0.1 0.0001 22.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EKE41316.1 - 0.00068 19.8 0.6 0.0014 18.8 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EKE41316.1 - 0.0016 18.2 0.4 0.0026 17.6 0.3 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EKE41316.1 - 0.0029 17.8 0.2 0.0077 16.4 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.10 EKE41316.1 - 0.0083 15.8 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 BED zinc finger zf-DBF PF07535.7 EKE41316.1 - 0.0091 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.2 EKE41316.1 - 0.02 14.9 0.2 0.047 13.8 0.0 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Rtf2 PF04641.7 EKE41316.1 - 0.71 9.0 12.6 0.85 8.7 8.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Muted PF14942.1 EKE41317.1 - 0.11 12.4 0.3 0.11 12.4 0.2 1.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2018 PF09442.5 EKE41317.1 - 0.11 13.0 3.9 0.32 11.5 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) CENP-U PF13097.1 EKE41317.1 - 0.12 12.3 1.2 0.18 11.6 0.8 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit TCTP PF00838.12 EKE41317.1 - 0.13 12.2 1.9 3.9 7.4 0.2 2.3 2 0 0 2 2 2 0 Translationally controlled tumour protein KIP1 PF07765.7 EKE41317.1 - 0.61 9.9 2.1 2.8 7.8 0.4 2.2 2 0 0 2 2 2 0 KIP1-like protein RNase_PH_C PF03725.10 EKE41318.1 - 9.9e-11 41.4 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 EKE41318.1 - 3e-10 40.5 0.0 5.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pkinase_Tyr PF07714.12 EKE41319.1 - 8.7e-54 182.3 0.2 1.6e-53 181.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41319.1 - 1.1e-50 172.2 0.3 1.7e-50 171.6 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 EKE41319.1 - 0.00025 20.4 1.2 0.00035 19.9 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EKE41319.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE41319.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Na_sulph_symp PF00939.14 EKE41319.1 - 0.17 10.7 0.8 0.29 9.9 0.5 1.2 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region TAFII28 PF04719.9 EKE41320.1 - 4e-05 23.3 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region ATP-synt_D PF01813.12 EKE41320.1 - 0.07 12.6 0.1 1.3 8.5 0.1 2.0 1 1 1 2 2 2 0 ATP synthase subunit D CBFD_NFYB_HMF PF00808.18 EKE41320.1 - 0.087 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RasGAP PF00616.14 EKE41321.1 - 0.00018 21.2 14.1 0.0029 17.2 0.8 3.2 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase YbaB_DNA_bd PF02575.11 EKE41321.1 - 0.18 11.6 1.2 0.84 9.5 0.0 2.5 3 0 0 3 3 3 0 YbaB/EbfC DNA-binding family Gelsolin PF00626.17 EKE41323.1 - 4.8e-37 125.5 1.5 4.2e-14 51.9 0.0 4.8 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.14 EKE41323.1 - 1.3e-09 37.5 6.8 3.6e-09 36.1 4.7 1.9 1 0 0 1 1 1 1 Villin headpiece domain HAD PF12710.2 EKE41324.1 - 4.9e-15 56.1 0.0 3.4e-14 53.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EKE41324.1 - 5.1e-13 48.5 0.1 5.1e-13 48.5 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKE41324.1 - 1.7e-11 44.9 0.2 1.3e-10 42.0 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sushi_2 PF09014.5 EKE41324.1 - 0.0043 16.7 1.2 0.34 10.6 0.0 3.2 2 0 0 2 2 2 1 Beta-2-glycoprotein-1 fifth domain Hydrolase_3 PF08282.7 EKE41324.1 - 0.73 9.3 28.2 0.16 11.5 8.2 4.3 2 2 2 4 4 4 0 haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 EKE41325.1 - 9.3e-15 54.0 0.0 1.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41325.1 - 2.4e-11 43.4 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41325.1 - 1.8e-08 34.1 0.0 4.4e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cu-oxidase_3 PF07732.10 EKE41325.1 - 0.086 12.5 0.7 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Multicopper oxidase PDCD2_C PF04194.8 EKE41326.1 - 6.9e-32 110.3 0.7 1.1e-31 109.6 0.1 1.6 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-HIT PF04438.11 EKE41326.1 - 0.0017 17.9 11.0 0.0017 17.9 7.6 4.1 4 0 0 4 4 4 1 HIT zinc finger zf-ISL3 PF14690.1 EKE41326.1 - 8 6.5 17.9 0.69 9.9 0.2 5.1 5 0 0 5 5 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 LRR_5 PF13306.1 EKE41327.1 - 3.4e-39 133.4 24.5 9.4e-25 86.7 9.0 2.6 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41327.1 - 2.4e-16 59.2 9.1 4e-07 29.6 0.1 4.8 2 2 2 4 4 4 4 Leucine rich repeat Metallophos PF00149.23 EKE41329.1 - 2.7e-07 30.2 0.0 8.2e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE41329.1 - 8.7e-06 25.6 0.0 3e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_1c PF00749.16 EKE41332.1 - 2.1e-104 348.5 0.0 2.1e-104 348.5 0.0 1.9 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EKE41332.1 - 4.1e-49 166.5 0.3 3.5e-48 163.5 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EKE41332.1 - 2.6e-36 124.6 3.4 2.6e-36 124.6 2.4 2.2 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF4460 PF14687.1 EKE41332.1 - 0.035 13.8 0.8 2.8 7.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) FAM75 PF14650.1 EKE41332.1 - 0.23 10.8 2.8 0.36 10.1 1.9 1.2 1 0 0 1 1 1 0 FAM75 family tRNA_synt_1c_R2 PF04557.10 EKE41332.1 - 0.83 10.3 9.9 11 6.8 6.9 2.4 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 GATA PF00320.22 EKE41333.1 - 1.1e-10 40.7 5.4 2.5e-10 39.5 3.7 1.6 1 0 0 1 1 1 1 GATA zinc finger Cytochrome_C7 PF14522.1 EKE41333.1 - 0.14 11.7 2.5 0.24 11.0 1.7 1.5 1 0 0 1 1 1 0 Cytochrome c7 Sulfotransfer_3 PF13469.1 EKE41334.1 - 1.4e-09 39.0 0.0 3.4e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EKE41334.1 - 1.7e-07 30.7 6.0 2e-06 27.2 4.2 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 EKE41334.1 - 0.0064 16.0 0.7 0.29 10.5 0.5 2.2 1 1 0 1 1 1 1 Stf0 sulphotransferase SRPRB PF09439.5 EKE41334.1 - 0.049 12.8 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4116 PF13475.1 EKE41334.1 - 0.11 12.0 1.2 0.3 10.5 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) UCH PF00443.24 EKE41335.1 - 6e-38 130.4 10.5 6e-38 130.4 7.3 4.2 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 EKE41336.1 - 9.4e-28 97.0 0.4 2e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41336.1 - 3.8e-14 52.3 0.0 5.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Rad17 PF03215.10 EKE41337.1 - 6.2e-11 41.6 13.2 3.4e-10 39.2 0.4 3.9 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EKE41337.1 - 3.5e-05 22.8 1.2 5.9e-05 22.0 0.2 1.9 2 0 0 2 2 2 1 NB-ARC domain DUF258 PF03193.11 EKE41337.1 - 4e-05 22.8 0.2 4e-05 22.8 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKE41337.1 - 6.4e-05 23.2 0.6 0.00014 22.1 0.4 1.7 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 EKE41337.1 - 8.3e-05 22.4 0.2 0.00028 20.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 EKE41337.1 - 0.00021 21.5 0.0 0.00059 20.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKE41337.1 - 0.00022 21.0 1.2 0.00043 20.0 0.2 2.0 2 0 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 EKE41337.1 - 0.00027 19.9 0.0 0.00052 18.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 EKE41337.1 - 0.0015 19.3 0.1 0.0049 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EKE41337.1 - 0.0016 18.5 0.0 0.0058 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EKE41337.1 - 0.004 16.4 0.1 0.0089 15.2 0.1 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RNA12 PF10443.4 EKE41337.1 - 0.0053 15.3 0.3 0.0053 15.3 0.2 1.9 2 0 0 2 2 2 1 RNA12 protein NACHT PF05729.7 EKE41337.1 - 0.0059 16.2 0.1 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 EKE41337.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EKE41337.1 - 0.0086 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 ASCH PF04266.9 EKE41337.1 - 0.012 16.0 1.8 0.025 14.9 0.3 2.2 2 0 0 2 2 2 0 ASCH domain AAA_18 PF13238.1 EKE41337.1 - 0.014 15.7 0.6 0.099 12.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EKE41337.1 - 0.021 14.3 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EKE41337.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 EKE41337.1 - 0.038 13.5 0.4 0.24 10.9 0.3 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EKE41337.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EKE41337.1 - 0.046 13.5 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKE41337.1 - 0.048 12.7 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Head-tail_con PF12236.3 EKE41337.1 - 0.1 10.9 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Flavoprotein PF02441.14 EKE41337.1 - 0.11 12.1 0.2 1.9 8.1 0.0 2.5 1 1 1 2 2 2 0 Flavoprotein AAA_25 PF13481.1 EKE41337.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKE41337.1 - 0.15 12.0 5.3 0.94 9.3 3.7 2.5 1 1 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.10 EKE41337.1 - 1.2 8.4 6.1 4.2 6.7 0.1 2.8 2 0 0 2 2 2 0 Tim10/DDP family zinc finger AAA_23 PF13476.1 EKE41337.1 - 2.7 8.2 16.0 1.6e+02 2.4 11.1 3.2 1 1 0 1 1 1 0 AAA domain LRR_5 PF13306.1 EKE41338.1 - 2.7e-54 182.3 47.8 6.4e-19 67.9 4.3 4.8 5 0 0 5 5 5 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41338.1 - 9.6e-24 82.9 24.9 8.8e-07 28.5 1.2 7.1 5 1 2 7 7 7 6 Leucine rich repeat Macro PF01661.16 EKE41339.1 - 1e-31 109.2 0.1 4.4e-31 107.2 0.0 2.1 2 0 0 2 2 2 1 Macro domain SIR2 PF02146.12 EKE41339.1 - 1.7e-07 31.1 0.3 1.5e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 Sir2 family 4HBT PF03061.17 EKE41341.1 - 0.0093 16.0 0.2 0.013 15.5 0.1 1.4 1 1 0 1 1 1 1 Thioesterase superfamily DUF1667 PF07892.6 EKE41341.1 - 0.076 12.7 1.6 0.34 10.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1667) Exo_endo_phos PF03372.18 EKE41342.1 - 1.6e-20 74.1 0.0 2.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tubulin PF00091.20 EKE41343.1 - 5.6e-11 42.6 0.2 5.6e-11 42.6 0.1 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain RabGAP-TBC PF00566.13 EKE41344.1 - 3.4e-38 131.2 2.4 4.4e-38 130.8 1.7 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CAP18_C PF12153.3 EKE41344.1 - 0.044 13.4 0.6 0.1 12.2 0.4 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) DUF1129 PF06570.6 EKE41345.1 - 0.0019 17.5 3.7 0.0019 17.5 2.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) DUF373 PF04123.8 EKE41345.1 - 0.0043 16.1 3.7 0.0043 16.1 2.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF373) Bax1-I PF01027.15 EKE41345.1 - 0.01 15.4 2.6 0.01 15.4 1.8 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Tetraspannin PF00335.15 EKE41345.1 - 0.013 14.7 25.8 3.9 6.6 18.0 3.5 1 1 0 1 1 1 0 Tetraspanin family DUF3188 PF11384.3 EKE41345.1 - 0.023 14.2 5.0 0.31 10.6 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) 7TMR-DISM_7TM PF07695.6 EKE41345.1 - 0.039 13.6 11.8 0.086 12.5 5.1 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF308 PF03729.8 EKE41345.1 - 0.071 13.1 9.2 1.5 8.8 0.4 3.0 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) BCD PF15461.1 EKE41345.1 - 0.09 12.1 1.9 0.094 12.1 0.6 1.5 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase Xan_ur_permease PF00860.15 EKE41345.1 - 0.13 10.7 6.2 0.052 12.0 2.9 1.4 1 1 0 1 1 1 0 Permease family Polysacc_synt_C PF14667.1 EKE41345.1 - 0.14 11.9 7.7 0.018 14.8 2.3 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF3816 PF12822.2 EKE41345.1 - 0.27 11.0 14.2 0.51 10.2 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF3754 PF12576.3 EKE41345.1 - 0.45 10.1 2.5 0.34 10.5 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3754) SecE PF00584.15 EKE41345.1 - 0.7 9.5 0.0 0.7 9.5 0.0 2.8 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex ABC2_membrane_5 PF13346.1 EKE41345.1 - 0.92 8.7 22.4 0.33 10.2 11.4 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein 2TM PF13239.1 EKE41345.1 - 1.3 9.1 4.1 1.5 8.9 0.1 2.5 1 1 1 2 2 2 0 2TM domain FtsX PF02687.16 EKE41345.1 - 8.2 6.2 13.7 0.53 10.0 1.6 2.8 1 1 1 2 2 2 0 FtsX-like permease family DENN PF02141.16 EKE41346.1 - 1.4e-16 60.8 5.6 1.4e-16 60.8 3.9 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain DSPc PF00782.15 EKE41348.1 - 2.8e-08 33.4 0.0 5.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE41348.1 - 3.7e-06 26.4 0.2 8e-06 25.3 0.1 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EKE41348.1 - 7.1e-05 23.1 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EKE41348.1 - 0.01 15.2 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKE41348.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 EKE41348.1 - 0.085 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Tic20 PF09685.5 EKE41349.1 - 3.5e-07 30.1 21.3 4.2e-07 29.9 14.8 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF3611 PF12263.3 EKE41350.1 - 0.0026 17.1 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) PsbN PF02468.10 EKE41350.1 - 5.9 6.5 5.8 10 5.8 4.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) HCaRG PF07258.9 EKE41353.1 - 6.7e-18 64.8 4.4 9.8e-18 64.3 3.1 1.2 1 0 0 1 1 1 1 HCaRG protein Trp_repressor PF01371.14 EKE41353.1 - 0.066 13.1 1.2 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Trp repressor protein Rho_Binding PF08912.6 EKE41353.1 - 0.44 10.8 0.1 0.44 10.8 0.1 2.8 3 0 0 3 3 3 0 Rho Binding Proteasome PF00227.21 EKE41354.1 - 2.2e-45 154.2 0.0 2.6e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Mic1 PF07035.7 EKE41355.1 - 1.5e-09 37.4 0.4 4.9e-09 35.7 0.3 1.9 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like PP2C_2 PF13672.1 EKE41356.1 - 3.8e-10 39.5 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE41356.1 - 0.00024 20.8 0.0 0.00051 19.7 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EKE41356.1 - 0.0023 17.3 0.6 0.011 15.2 0.1 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C Abhydrolase_5 PF12695.2 EKE41357.1 - 1.3e-10 41.1 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 EKE41357.1 - 2.3e-07 29.9 0.0 3.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.11 EKE41357.1 - 2.3e-06 27.1 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EKE41357.1 - 3.8e-05 23.0 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EKE41357.1 - 0.00025 20.9 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family TLC PF03219.9 EKE41357.1 - 0.0076 14.7 0.3 0.0099 14.3 0.2 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter Abhydrolase_3 PF07859.8 EKE41357.1 - 0.062 12.8 0.0 0.16 11.4 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EKE41357.1 - 0.066 12.6 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF3137 PF11335.3 EKE41357.1 - 0.08 12.6 0.3 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) DUF829 PF05705.9 EKE41357.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) PseudoU_synth_2 PF00849.17 EKE41358.1 - 5e-26 91.4 0.1 9.2e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EKE41358.1 - 0.0066 15.8 0.4 0.0066 15.8 0.2 2.5 3 0 0 3 3 3 1 S4 domain TruB_N PF01509.13 EKE41358.1 - 0.022 14.9 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) HSP70 PF00012.15 EKE41359.1 - 1.3e-29 102.6 5.7 4.7e-24 84.2 2.6 4.2 1 1 2 4 4 4 2 Hsp70 protein TPR_11 PF13414.1 EKE41359.1 - 4.6e-13 48.5 1.2 5.7e-09 35.5 0.2 2.8 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKE41359.1 - 1.4e-10 40.2 1.8 0.00052 19.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat MreB_Mbl PF06723.8 EKE41359.1 - 6.4e-09 34.8 2.2 1.1e-08 34.0 1.5 1.5 1 0 0 1 1 1 1 MreB/Mbl protein TPR_2 PF07719.12 EKE41359.1 - 8.2e-06 25.3 1.1 0.07 13.0 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EKE41359.1 - 9e-06 25.7 0.3 4.2e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EKE41359.1 - 0.00097 19.0 5.5 0.03 14.2 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE41359.1 - 0.036 14.4 1.6 4.6 7.6 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41359.1 - 0.087 13.0 0.5 14 6.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41359.1 - 0.14 12.8 0.2 0.46 11.2 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41359.1 - 0.15 11.9 0.2 0.15 11.9 0.1 4.0 3 1 1 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE41359.1 - 0.29 11.6 2.0 31 5.3 0.1 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat FtsA PF14450.1 EKE41359.1 - 0.81 9.5 5.4 15 5.4 3.7 3.4 1 1 0 1 1 1 0 Cell division protein FtsA Rap_GAP PF02145.10 EKE41360.1 - 2e-46 157.7 1.5 3.4e-46 156.9 1.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP RRM_1 PF00076.17 EKE41361.1 - 2.3e-26 91.1 3.0 9.4e-15 54.0 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41361.1 - 6.5e-24 83.5 0.7 1.5e-12 47.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41361.1 - 2.2e-15 56.3 0.5 7.8e-07 28.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE41361.1 - 9.6e-08 31.6 0.4 0.016 14.9 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 EKE41361.1 - 4.3e-05 23.0 0.0 0.012 15.1 0.0 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF1866) RRM_3 PF08777.6 EKE41361.1 - 0.0014 18.4 0.4 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM PF05172.8 EKE41361.1 - 0.0081 15.8 1.2 0.026 14.2 0.4 2.1 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif 7TMR-HDED PF07697.6 EKE41361.1 - 0.022 14.5 0.6 0.035 13.8 0.4 1.5 1 0 0 1 1 1 0 7TM-HD extracellular Sec10 PF07393.6 EKE41363.1 - 1.1e-42 146.1 39.7 1.1e-23 83.4 4.6 2.4 2 1 1 3 3 3 2 Exocyst complex component Sec10 PBD PF00786.23 EKE41364.1 - 4.6e-05 23.7 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PAT1 PF09770.4 EKE41364.1 - 0.72 8.0 15.6 0.84 7.7 10.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 EKE41365.1 - 3.4e-26 92.8 15.7 3.4e-26 92.8 10.9 9.2 3 2 3 6 6 6 1 AAA domain SbcCD_C PF13558.1 EKE41365.1 - 1.1e-08 34.8 0.0 5.2e-08 32.6 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EKE41365.1 - 2.4e-08 34.2 2.0 2.8e-05 24.2 0.2 6.9 4 2 1 5 5 5 2 AAA domain SMC_N PF02463.14 EKE41365.1 - 1.5e-07 30.8 0.0 1.5e-07 30.8 0.0 5.9 4 2 3 7 7 7 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKE41365.1 - 0.00043 19.7 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EKE41365.1 - 0.0021 16.6 0.0 0.0021 16.6 0.0 7.2 3 1 3 7 7 7 4 AAA domain AAA_19 PF13245.1 EKE41365.1 - 0.0066 16.1 0.1 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EKE41365.1 - 0.62 10.0 0.0 0.62 10.0 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain LRR_5 PF13306.1 EKE41366.1 - 4.1e-55 184.9 32.1 3e-26 91.6 0.9 4.1 1 1 2 4 4 4 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41366.1 - 1.8e-27 94.8 9.1 1.5e-06 27.8 0.0 6.1 3 1 4 7 7 7 7 Leucine rich repeat Swi5 PF07061.6 EKE41367.1 - 0.011 15.4 0.1 0.03 14.0 0.1 1.8 1 0 0 1 1 1 0 Swi5 PLAC8 PF04749.12 EKE41368.1 - 0.087 13.3 1.9 0.12 12.9 0.6 1.7 2 0 0 2 2 2 0 PLAC8 family DUF966 PF06136.8 EKE41369.1 - 0.015 14.7 0.5 0.023 14.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HECT PF00632.20 EKE41370.1 - 4.3e-94 315.2 1.0 4.3e-94 315.2 0.7 3.2 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Telomere_reg-2 PF10193.4 EKE41371.1 - 0.14 12.4 4.9 0.063 13.5 1.0 2.1 2 0 0 2 2 2 0 Telomere length regulation protein BAT2_N PF07001.6 EKE41371.1 - 0.15 12.3 2.7 7.6 6.8 0.0 2.3 2 0 0 2 2 2 0 BAT2 N-terminus Apyrase PF06079.6 EKE41372.1 - 1e-83 280.8 1.6 1.3e-83 280.5 1.1 1.0 1 0 0 1 1 1 1 Apyrase Ribosomal_L7Ae PF01248.21 EKE41373.1 - 2.7e-24 84.4 0.1 3.4e-24 84.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EKE41373.1 - 0.00013 21.8 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EKE41373.1 - 0.0054 16.4 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain PqqD PF05402.7 EKE41373.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) SprT-like PF10263.4 EKE41374.1 - 5.7e-34 117.0 3.8 7.6e-34 116.6 2.6 1.2 1 0 0 1 1 1 1 SprT-like family DUF3267 PF11667.3 EKE41374.1 - 0.036 14.2 1.3 0.059 13.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3267) LRR_8 PF13855.1 EKE41375.1 - 4.2e-08 32.8 9.5 0.0022 17.6 0.2 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EKE41375.1 - 4.9e-06 26.0 14.2 0.008 15.7 0.1 4.6 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EKE41375.1 - 2.9e-05 23.7 1.6 9.7e-05 21.9 1.1 2.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EKE41375.1 - 0.015 15.3 7.5 2.2 8.6 0.0 4.7 3 1 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 EKE41375.1 - 0.061 13.5 6.4 5.2 7.7 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EKE41375.1 - 0.33 11.1 13.5 1.5 9.1 0.0 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat DUF3993 PF13158.1 EKE41375.1 - 0.44 10.3 4.7 0.7 9.7 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) MIG-14_Wnt-bd PF06664.7 EKE41376.1 - 6.6e-18 64.5 32.6 9.2e-18 64.0 22.6 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF912 PF06024.7 EKE41376.1 - 0.82 9.7 8.9 7.7 6.6 1.3 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Vpu PF00558.14 EKE41376.1 - 2.7 7.6 7.4 0.19 11.3 0.6 2.4 2 0 0 2 2 2 0 Vpu protein ATP-synt_D PF01813.12 EKE41377.1 - 5.7e-62 208.7 6.5 7.6e-62 208.3 4.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit D GP41 PF00517.12 EKE41377.1 - 0.41 10.1 3.4 0.44 10.0 0.1 2.4 2 1 0 2 2 2 0 Retroviral envelope protein BCIP PF13862.1 EKE41377.1 - 2.5 7.5 9.7 0.64 9.4 4.2 1.8 1 1 1 2 2 2 0 p21-C-terminal region-binding protein RRM_1 PF00076.17 EKE41378.1 - 4.1e-36 122.4 4.2 3.5e-18 64.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41378.1 - 1.7e-25 88.7 0.6 3.5e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41378.1 - 1.5e-13 50.4 0.6 1.1e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EKE41378.1 - 4.2e-06 26.1 0.4 0.076 12.5 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain CSD PF00313.17 EKE41378.1 - 0.15 11.8 2.0 13 5.6 0.1 2.5 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain TLD PF07534.11 EKE41379.1 - 0.053 13.5 3.9 0.15 12.0 2.7 1.9 1 1 0 1 1 1 0 TLD Toxin_64 PF15542.1 EKE41379.1 - 0.18 12.3 0.2 0.18 12.3 0.1 2.7 3 0 0 3 3 3 0 Putative toxin 64 Beach PF02138.13 EKE41380.1 - 1e-97 326.8 2.5 1e-97 326.8 1.7 1.9 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 EKE41380.1 - 4.1e-09 36.2 8.0 5e-07 29.5 1.4 3.9 2 2 0 2 2 2 2 PH domain associated with Beige/BEACH GRAM PF02893.15 EKE41380.1 - 0.00028 20.3 1.4 0.12 11.9 0.1 3.5 3 0 0 3 3 3 2 GRAM domain HEAT_2 PF13646.1 EKE41381.1 - 1.4e-13 50.9 1.3 0.0058 16.8 0.0 7.3 5 3 3 8 8 8 4 HEAT repeats HEAT PF02985.17 EKE41381.1 - 2.3e-08 33.4 8.4 2.1 8.6 0.0 9.6 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.1 EKE41381.1 - 1.3e-06 28.7 0.6 6.5 7.3 0.0 7.4 9 1 0 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EKE41381.1 - 0.00091 19.5 10.1 7.3 7.0 0.0 6.6 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region Ku_N PF03731.10 EKE41381.1 - 0.015 14.7 0.7 0.034 13.5 0.4 1.6 1 1 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain RIX1 PF08167.7 EKE41381.1 - 0.037 13.7 6.6 4.4 6.9 0.4 3.9 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis GrpE PF01025.14 EKE41381.1 - 0.27 10.7 5.7 8.4 5.9 0.1 3.2 3 0 0 3 3 3 0 GrpE Arm PF00514.18 EKE41381.1 - 0.27 11.1 4.3 45 4.0 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat S_100 PF01023.14 EKE41382.1 - 0.13 11.6 3.6 2.4 7.5 0.0 3.1 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain DUF4277 PF14104.1 EKE41383.1 - 0.026 14.6 0.1 0.096 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4277) Pup PF05639.6 EKE41383.1 - 0.24 11.9 2.2 0.62 10.6 0.0 2.9 4 0 0 4 4 4 0 Pup-like protein CPG4 PF15481.1 EKE41383.1 - 9.2 6.6 13.8 0.066 13.5 1.9 3.0 5 0 0 5 5 5 0 Chondroitin proteoglycan 4 Lipase_3 PF01764.20 EKE41385.1 - 1.8e-06 27.6 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EKE41385.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE41385.1 - 0.012 15.1 0.0 0.99 8.9 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold TMEM154 PF15102.1 EKE41385.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family UPF0227 PF05728.7 EKE41385.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) IncA PF04156.9 EKE41385.1 - 6.1 6.3 5.7 3 7.3 0.3 2.7 2 1 1 3 3 3 0 IncA protein WD40 PF00400.27 EKE41386.1 - 2.5e-43 144.4 20.6 1.1e-07 31.4 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EKE41386.1 - 3.7e-11 43.1 3.4 2.8e-05 23.9 0.1 3.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EKE41386.1 - 0.0078 15.0 0.0 0.45 9.2 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region DnaJ PF00226.26 EKE41387.1 - 1.4e-15 56.7 2.4 1.4e-15 56.7 1.7 2.4 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.1 EKE41387.1 - 0.0053 16.1 0.0 0.015 14.6 0.0 1.7 1 0 0 1 1 1 1 A repeated domain in UCH-protein DsrC PF04358.8 EKE41387.1 - 0.18 12.0 4.3 0.16 12.2 0.8 2.4 2 1 0 2 2 2 0 DsrC like protein DUF3870 PF12986.2 EKE41387.1 - 1.6 9.0 7.4 11 6.3 0.1 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF3870) Pkinase_Tyr PF07714.12 EKE41388.1 - 2.1e-58 197.4 0.0 3e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41388.1 - 5.4e-51 173.2 0.0 8e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1034 PF06280.7 EKE41388.1 - 0.017 15.5 0.7 0.029 14.7 0.1 1.7 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) Kdo PF06293.9 EKE41388.1 - 0.018 14.0 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE41388.1 - 0.089 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Filament PF00038.16 EKE41389.1 - 0.0037 16.7 9.8 0.0061 16.0 6.8 1.3 1 0 0 1 1 1 1 Intermediate filament protein zf-C4H2 PF10146.4 EKE41389.1 - 0.0039 17.2 7.9 0.0043 17.0 5.5 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein CCDC155 PF14662.1 EKE41389.1 - 0.011 15.3 14.5 0.029 13.9 9.9 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Striatin PF08232.7 EKE41389.1 - 0.02 15.2 9.2 0.087 13.1 0.4 2.2 1 1 1 2 2 2 0 Striatin family Mod_r PF07200.8 EKE41389.1 - 0.022 14.6 9.1 0.022 14.6 6.3 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.16 EKE41389.1 - 0.049 13.5 14.1 3 7.8 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF869 PF05911.6 EKE41389.1 - 0.055 11.7 13.4 0.064 11.4 9.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Ax_dynein_light PF10211.4 EKE41389.1 - 0.064 13.0 12.4 3.1 7.5 7.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Diphthamide_syn PF01866.12 EKE41389.1 - 0.082 12.1 1.4 0.1 11.8 1.0 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Pox_A_type_inc PF04508.7 EKE41389.1 - 0.1 12.4 7.3 5.1 7.1 0.0 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat APG6 PF04111.7 EKE41389.1 - 0.12 11.3 14.7 0.14 11.1 10.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS5 PF14817.1 EKE41389.1 - 0.13 10.7 7.3 0.15 10.5 5.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Retrotrans_gag PF03732.12 EKE41389.1 - 0.19 11.8 2.3 0.13 12.3 0.5 1.5 2 0 0 2 2 1 0 Retrotransposon gag protein DUF2051 PF09738.4 EKE41389.1 - 0.19 10.9 14.0 0.43 9.8 0.2 2.0 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) DUF3450 PF11932.3 EKE41389.1 - 0.28 10.3 6.4 0.45 9.7 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 EKE41389.1 - 0.41 11.0 13.3 0.45 10.8 6.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EKE41389.1 - 0.46 10.4 12.5 12 5.9 6.5 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 EKE41389.1 - 0.82 9.1 12.8 0.78 9.2 5.7 2.2 1 1 1 2 2 2 0 Septum formation initiator Spc7 PF08317.6 EKE41389.1 - 0.94 8.0 13.2 1.5 7.3 9.1 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.14 EKE41389.1 - 1 8.8 10.2 0.78 9.2 6.1 1.5 1 1 1 2 2 2 0 GrpE Nup54 PF13874.1 EKE41389.1 - 1.1 8.8 6.8 1.6 8.4 4.7 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Mgr1 PF08602.5 EKE41389.1 - 1.2 8.0 6.4 1.6 7.7 4.4 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit LRS4 PF10422.4 EKE41389.1 - 1.4 8.2 11.0 1.7 7.9 7.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TBPIP PF07106.8 EKE41389.1 - 1.7 8.1 15.8 3.4 7.1 7.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0449 PF15136.1 EKE41389.1 - 2.3 8.4 6.2 1.9 8.7 2.3 2.1 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Atg14 PF10186.4 EKE41389.1 - 2.6 6.9 10.8 3.7 6.4 7.5 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Frigida PF07899.6 EKE41389.1 - 2.9 6.5 10.0 4.7 5.8 6.3 1.7 1 1 1 2 2 2 0 Frigida-like protein IncA PF04156.9 EKE41389.1 - 5.7 6.4 13.6 16 5.0 9.4 1.6 1 1 0 1 1 1 0 IncA protein tRNA-synt_1d PF00750.14 EKE41390.1 - 4.5e-79 265.8 1.6 6.3e-79 265.3 1.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EKE41390.1 - 2.3e-26 92.0 0.0 7.4e-26 90.4 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EKE41390.1 - 7.6e-14 52.0 0.4 2.6e-13 50.3 0.3 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Peptidase_C1 PF00112.18 EKE41391.1 - 7.6e-09 35.7 2.7 2.6e-08 34.0 0.2 2.2 2 0 0 2 2 2 1 Papain family cysteine protease RasGEF PF00617.14 EKE41392.1 - 2e-31 109.1 1.8 3.3e-31 108.4 0.3 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE41392.1 - 0.00033 20.7 0.0 0.00033 20.7 0.0 3.0 3 1 0 3 3 3 1 RasGEF N-terminal motif RasGEF PF00617.14 EKE41393.1 - 4.2e-13 49.4 5.8 5.9e-12 45.7 4.1 2.3 1 1 0 1 1 1 1 RasGEF domain DUF1765 PF08578.5 EKE41394.1 - 3.1e-08 33.7 1.5 3.1e-08 33.7 1.1 3.0 4 1 0 4 4 4 1 Protein of unknown function (DUF1765) DUF3546 PF12066.3 EKE41395.1 - 0.054 13.5 5.7 0.058 13.4 0.6 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF3546) FYVE PF01363.16 EKE41396.1 - 0.00043 20.1 10.0 0.0014 18.5 7.0 1.9 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.18 EKE41396.1 - 1.5 8.7 4.7 74 3.3 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Seryl_tRNA_N PF02403.17 EKE41398.1 - 1.3e-05 25.1 9.5 1.3e-05 25.1 6.6 5.6 2 1 3 5 5 5 3 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EKE41398.1 - 0.0012 18.2 1.7 0.0012 18.2 1.2 7.7 3 1 6 9 9 9 2 Septum formation initiator ADIP PF11559.3 EKE41398.1 - 0.013 15.3 13.7 0.013 15.3 9.5 5.6 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding Med25_SD1 PF11235.3 EKE41398.1 - 6.1 7.1 11.6 0.72 10.1 0.4 2.6 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 RNA_pol_L_2 PF13656.1 EKE41399.1 - 3.5e-21 74.4 0.3 4.3e-21 74.1 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EKE41399.1 - 1.9e-10 39.7 0.0 2.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase_Tyr PF07714.12 EKE41400.1 - 2.5e-37 128.3 0.0 3.2e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41400.1 - 6.3e-37 127.1 0.0 8.2e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EKE41400.1 - 0.0025 16.9 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKE41400.1 - 0.0053 15.7 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE41400.1 - 0.19 11.4 0.0 0.5 10.0 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family F-box PF00646.28 EKE41401.1 - 0.0029 17.2 2.7 0.01 15.5 0.2 3.1 3 0 0 3 3 3 1 F-box domain DUF2404 PF10296.4 EKE41401.1 - 0.033 14.3 1.9 0.28 11.3 0.2 3.0 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) EF1_GNE PF00736.14 EKE41403.1 - 1.2e-28 98.6 0.9 1.9e-28 97.9 0.6 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Tic20 PF09685.5 EKE41404.1 - 0.00065 19.6 14.2 0.00077 19.4 9.8 1.1 1 0 0 1 1 1 1 Tic20-like protein Cut8_N PF14482.1 EKE41404.1 - 0.072 13.0 0.0 0.094 12.7 0.0 1.1 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Ribosomal_L27e PF01777.13 EKE41405.1 - 3.4e-21 75.1 4.2 5.8e-21 74.4 2.9 1.4 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EKE41405.1 - 6.2e-06 25.7 1.9 6.2e-06 25.7 1.3 2.1 2 0 0 2 2 2 1 KOW motif DUF217 PF02697.9 EKE41407.1 - 2.5 8.4 6.6 4.3 7.6 0.2 3.1 2 1 0 2 2 2 0 Uncharacterized ACR, COG1753 AMP-binding PF00501.23 EKE41409.1 - 1.1e-22 80.0 0.0 4.3e-22 78.0 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Prog_receptor PF02161.10 EKE41409.1 - 6.4 5.4 6.0 12 4.6 4.2 1.3 1 0 0 1 1 1 0 Progesterone receptor Coatomer_E PF04733.9 EKE41411.1 - 1.4e-09 37.5 0.4 1.8e-07 30.6 0.1 2.3 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_2 PF07719.12 EKE41411.1 - 2.2e-05 24.0 15.9 1.3 9.1 0.8 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EKE41411.1 - 2.2e-05 24.4 17.7 0.0032 17.5 0.3 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EKE41411.1 - 3.9e-05 24.1 2.1 0.6 10.8 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKE41411.1 - 9.3e-05 22.2 1.9 4.9 7.1 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKE41411.1 - 0.008 15.8 15.6 0.63 9.7 1.0 5.6 6 0 0 6 6 6 1 TPR repeat TPR_19 PF14559.1 EKE41411.1 - 0.013 15.8 6.1 0.064 13.5 0.0 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat T2SF PF00482.18 EKE41411.1 - 0.035 14.0 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F PPR PF01535.15 EKE41411.1 - 0.036 14.0 0.4 2.8 8.1 0.1 3.6 4 0 0 4 4 4 0 PPR repeat DUF2802 PF10975.3 EKE41411.1 - 0.057 13.1 0.0 6.3 6.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) PYRIN PF02758.11 EKE41411.1 - 0.33 10.6 2.8 2.5 7.8 0.3 2.6 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain TPR_1 PF00515.23 EKE41411.1 - 1.9 8.2 18.1 3.7 7.3 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41411.1 - 4.2 7.8 7.6 1.4e+02 3.0 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Abi PF02517.11 EKE41413.1 - 0.0001 22.3 23.7 0.0016 18.5 16.4 2.6 1 1 0 1 1 1 1 CAAX protease self-immunity EamA PF00892.15 EKE41413.1 - 0.00014 21.9 7.7 0.00014 21.9 5.3 4.2 3 2 1 5 5 5 1 EamA-like transporter family START PF01852.14 EKE41414.1 - 5.5e-05 22.5 0.0 6.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE41414.1 - 0.00033 20.3 0.1 0.00064 19.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) RhoGEF PF00621.15 EKE41415.1 - 8.6e-26 90.9 2.7 8.6e-26 90.9 1.8 1.9 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EKE41415.1 - 0.00016 21.8 2.3 0.00035 20.7 0.7 2.3 2 0 0 2 2 2 1 PH domain PH_10 PF15411.1 EKE41415.1 - 0.041 14.0 3.4 0.05 13.7 1.3 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PMC2NT PF08066.7 EKE41416.1 - 0.025 14.8 1.4 0.025 14.8 1.0 2.6 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Spectrin PF00435.16 EKE41416.1 - 0.039 14.2 0.5 0.039 14.2 0.3 2.8 2 1 1 3 3 3 0 Spectrin repeat U3_snoRNA_assoc PF08297.6 EKE41416.1 - 0.12 12.6 4.9 0.23 11.7 3.4 1.6 1 0 0 1 1 1 0 U3 snoRNA associated Serine_rich PF08824.5 EKE41416.1 - 0.33 10.6 6.0 2.2 7.9 1.2 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF948 PF06103.6 EKE41416.1 - 0.66 9.8 16.0 2.4 8.0 4.2 4.0 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.8 EKE41416.1 - 0.69 8.2 7.5 0.46 8.8 3.8 1.6 1 1 0 1 1 1 0 Tweety FlaC_arch PF05377.6 EKE41416.1 - 2.6 8.0 13.6 0.12 12.2 2.5 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Aconitase_C PF00694.14 EKE41416.1 - 4.4 7.4 9.0 0.76 9.8 3.4 1.8 2 0 0 2 2 2 0 Aconitase C-terminal domain AAA PF00004.24 EKE41418.1 - 1.3e-42 145.1 1.7 5.7e-36 123.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKE41418.1 - 3.1e-10 39.9 0.2 0.00015 21.5 0.0 3.7 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EKE41418.1 - 1.8e-06 28.0 0.0 4.3e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 EKE41418.1 - 1.3e-05 25.2 2.1 0.043 13.7 0.0 3.6 2 2 2 4 4 4 2 AAA ATPase domain TIP49 PF06068.8 EKE41418.1 - 2.1e-05 23.4 0.0 0.095 11.3 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EKE41418.1 - 2.9e-05 23.9 0.4 0.24 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EKE41418.1 - 4.4e-05 22.5 0.0 0.0011 17.9 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EKE41418.1 - 0.0001 21.8 0.6 0.06 12.9 0.0 3.3 3 1 1 4 4 3 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EKE41418.1 - 0.00021 21.4 0.1 1.3 9.1 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_2 PF07724.9 EKE41418.1 - 0.00023 21.1 0.3 0.0018 18.2 0.0 2.6 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EKE41418.1 - 0.00031 20.2 0.2 0.04 13.3 0.0 3.2 2 2 1 3 3 3 1 Sigma-54 interaction domain AAA_29 PF13555.1 EKE41418.1 - 0.00078 18.9 0.1 0.55 9.8 0.0 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EKE41418.1 - 0.0013 17.9 0.0 0.99 8.5 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EKE41418.1 - 0.0017 18.0 9.4 6.6 6.3 0.0 4.8 3 2 2 5 5 5 1 Archaeal ATPase DEAD PF00270.24 EKE41418.1 - 0.003 17.0 0.1 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_17 PF13207.1 EKE41418.1 - 0.0035 18.1 0.2 3 8.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EKE41418.1 - 0.0082 15.8 3.5 0.83 9.2 0.0 3.3 2 1 1 3 3 3 1 NACHT domain AAA_22 PF13401.1 EKE41418.1 - 0.012 15.7 8.6 2.5 8.2 0.1 4.4 2 2 1 3 3 3 0 AAA domain ABC_tran PF00005.22 EKE41418.1 - 0.013 15.7 1.0 4.2 7.6 0.0 3.2 4 0 0 4 4 3 0 ABC transporter RuvB_N PF05496.7 EKE41418.1 - 0.023 13.7 0.0 0.94 8.4 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EKE41418.1 - 0.045 12.9 1.0 0.44 9.7 0.0 3.0 3 1 1 4 4 4 0 PhoH-like protein AAA_19 PF13245.1 EKE41418.1 - 0.17 11.6 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Adaptin_N PF01602.15 EKE41419.1 - 2.5e-99 332.9 13.5 4.2e-99 332.2 9.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EKE41419.1 - 6.6e-13 48.7 0.1 0.0001 22.5 0.0 5.0 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EKE41419.1 - 3.6e-08 32.8 0.3 0.11 12.6 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 EKE41419.1 - 3.4e-06 27.0 7.5 0.00059 19.7 0.3 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EKE41419.1 - 0.0013 19.1 0.2 1.7 9.2 0.0 4.3 3 2 2 5 5 5 2 HEAT-like repeat Spc97_Spc98 PF04130.8 EKE41419.1 - 0.0051 15.1 0.5 0.0061 14.9 0.4 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family Pkinase_Tyr PF07714.12 EKE41420.1 - 9e-53 178.9 0.0 1.5e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41420.1 - 9.1e-50 169.2 0.0 2.1e-49 167.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Laminin_G_3 PF13385.1 EKE41420.1 - 9.9e-06 25.8 1.7 0.014 15.5 0.1 2.7 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily TMEM154 PF15102.1 EKE41420.1 - 8.3e-05 22.3 0.0 8.3e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 TMEM154 protein family Rifin_STEVOR PF02009.11 EKE41420.1 - 0.00017 21.3 0.3 0.00017 21.3 0.2 2.1 2 0 0 2 2 2 1 Rifin/stevor family EphA2_TM PF14575.1 EKE41420.1 - 0.00021 21.5 0.4 0.0005 20.4 0.3 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 EKE41420.1 - 0.0055 16.3 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 IncA protein DUF1080 PF06439.6 EKE41420.1 - 0.0078 16.1 0.1 3.9 7.3 0.0 2.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1080) stn_TNFRSF12A PF12191.3 EKE41420.1 - 0.0097 15.9 1.7 0.0097 15.9 1.2 1.8 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2681 PF10883.3 EKE41420.1 - 0.027 14.6 0.6 0.07 13.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Tmemb_9 PF05434.6 EKE41420.1 - 0.033 13.9 3.0 0.08 12.6 2.1 1.6 1 0 0 1 1 1 0 TMEM9 DUF1517 PF07466.6 EKE41420.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1191 PF06697.7 EKE41420.1 - 0.11 11.2 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) ASFV_J13L PF05568.6 EKE41420.1 - 6.9 6.1 10.0 0.063 12.8 0.4 2.3 3 0 0 3 3 3 0 African swine fever virus J13L protein LMBR1 PF04791.11 EKE41421.1 - 0.15 10.6 2.4 0.22 10.0 1.6 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein HhH-GPD PF00730.20 EKE41422.1 - 2.8e-15 56.5 0.0 6.3e-15 55.3 0.0 1.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EKE41422.1 - 7.9e-08 31.5 0.0 2.7e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EKE41422.1 - 0.00078 19.5 0.0 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.3 EKE41422.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.8 2 0 0 2 2 2 0 Pathogenicity locus HHH_8 PF14716.1 EKE41422.1 - 0.083 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain UbiA PF01040.13 EKE41423.1 - 0.053 12.7 13.4 0.014 14.6 7.1 1.4 1 1 0 1 1 1 0 UbiA prenyltransferase family DUF981 PF06168.6 EKE41423.1 - 0.066 12.9 6.9 0.11 12.2 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) CD20 PF04103.10 EKE41423.1 - 0.11 12.3 10.7 0.16 11.9 7.4 1.2 1 0 0 1 1 1 0 CD20-like family TctB PF07331.6 EKE41423.1 - 0.12 12.0 8.3 0.015 14.9 2.7 1.7 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family MacB_PCD PF12704.2 EKE41423.1 - 0.27 10.7 2.1 0.33 10.4 0.4 1.8 2 0 0 2 2 2 0 MacB-like periplasmic core domain DUF1146 PF06612.6 EKE41423.1 - 1 9.3 0.1 1 9.3 0.0 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1146) NPCC PF08058.6 EKE41423.1 - 1.3 8.8 4.6 4.2 7.2 1.4 2.0 2 0 0 2 2 2 0 Nuclear pore complex component Oxidored_q2 PF00420.19 EKE41423.1 - 4.2 7.0 13.1 0.044 13.3 0.8 2.4 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Acyltransferase PF01553.16 EKE41424.1 - 1.6e-16 59.9 0.1 2.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 EKE41425.1 - 3.4e-73 246.0 0.4 4.2e-73 245.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41425.1 - 2.2e-37 128.5 0.1 2.8e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE41425.1 - 8.4e-20 70.9 0.9 1.9e-19 69.7 0.6 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EKE41425.1 - 2.4e-09 36.5 0.0 1.5e-07 30.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like PH_11 PF15413.1 EKE41425.1 - 8.4e-09 35.6 2.4 5e-07 29.9 1.7 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EKE41425.1 - 3.4e-07 30.0 0.4 8.7e-07 28.7 0.2 1.8 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 EKE41425.1 - 4.8e-07 29.7 0.1 1.2e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EKE41425.1 - 0.00034 20.7 0.8 0.0021 18.2 0.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Phospholip_B PF04916.8 EKE41426.1 - 1.1e-94 317.5 10.7 1.6e-94 317.0 7.4 1.2 1 0 0 1 1 1 1 Phospholipase B TraD_N PF12615.3 EKE41426.1 - 0.0041 17.4 2.7 1.9 8.9 0.0 3.7 3 0 0 3 3 3 1 F sex factor protein N terminal Pkinase_Tyr PF07714.12 EKE41427.1 - 2e-55 187.6 0.0 2.7e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41427.1 - 2.1e-51 174.6 0.0 3.3e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EKE41427.1 - 3.6e-07 30.1 0.0 0.0059 16.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family TIG PF01833.19 EKE41427.1 - 0.076 13.0 1.4 0.36 10.8 0.2 2.7 2 1 0 2 2 2 0 IPT/TIG domain Ras PF00071.17 EKE41428.1 - 1.8e-47 160.7 2.4 2e-47 160.5 1.7 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE41428.1 - 1.1e-21 76.8 1.2 1.4e-21 76.5 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE41428.1 - 4.5e-18 65.8 0.1 7.4e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKE41428.1 - 9.3e-07 28.2 0.6 1.1e-06 27.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE41428.1 - 2.9e-06 26.6 0.1 5.4e-06 25.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE41428.1 - 1.1e-05 24.9 2.9 0.0001 21.8 2.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE41428.1 - 0.00038 20.4 0.3 0.00038 20.4 0.2 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Glyco_hydro_3_C PF01915.17 EKE41428.1 - 0.0048 16.4 0.1 0.0077 15.7 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain UPF0079 PF02367.12 EKE41428.1 - 0.0061 16.1 0.6 0.31 10.6 0.1 2.2 1 1 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EKE41428.1 - 0.085 12.3 0.3 0.16 11.4 0.2 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EKE41428.1 - 0.44 10.0 3.5 1.1 8.7 2.4 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation XPG_N PF00752.12 EKE41429.1 - 2.3e-20 72.7 0.0 6.9e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EKE41429.1 - 2.6e-20 72.2 0.2 1.3e-19 69.9 0.0 2.4 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.2 EKE41429.1 - 7.2e-05 22.3 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing E_raikovi_mat PF06360.6 EKE41429.1 - 0.18 12.0 3.7 5.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone Pkinase PF00069.20 EKE41431.1 - 1.3e-32 113.0 0.1 1.8e-32 112.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41431.1 - 4.5e-16 58.7 0.0 6.9e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41431.1 - 7.8e-05 21.7 1.0 0.00025 20.0 0.1 2.1 3 0 0 3 3 3 1 Kinase-like PIP49_C PF12260.3 EKE41431.1 - 0.00041 19.8 0.1 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 APH PF01636.18 EKE41431.1 - 0.00049 19.9 0.0 0.001 18.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Curto_V3 PF07436.6 EKE41432.1 - 0.029 14.4 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 Curtovirus V3 protein Ras PF00071.17 EKE41433.1 - 2e-10 40.2 0.1 2.2e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41433.1 - 0.0049 17.3 0.0 0.005 17.3 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Phage_holin_T PF11031.3 EKE41434.1 - 0.057 12.5 0.2 0.085 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage T holin SHP PF03579.8 EKE41434.1 - 0.14 11.5 0.3 0.14 11.5 0.2 1.6 2 0 0 2 2 2 0 Small hydrophobic protein PSI PF01437.20 EKE41434.1 - 5 7.3 13.9 11 6.2 8.2 2.3 2 1 0 2 2 2 0 Plexin repeat zf-C2H2_jaz PF12171.3 EKE41435.1 - 1.4e-06 28.2 3.0 3.1e-06 27.1 2.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKE41435.1 - 1e-05 25.5 1.6 1.9e-05 24.7 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF629 PF04780.7 EKE41435.1 - 0.018 13.6 0.0 0.02 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 EKE41435.1 - 0.067 13.5 2.1 0.12 12.7 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type LRR_5 PF13306.1 EKE41436.1 - 2.2e-89 295.7 48.4 7.5e-29 100.0 9.0 4.3 2 2 2 4 4 4 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41436.1 - 4.9e-41 138.3 26.9 7.3e-08 32.0 0.3 7.9 3 2 8 11 11 11 10 Leucine rich repeat DUF3538 PF12057.3 EKE41437.1 - 0.093 12.3 0.2 3.5 7.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3538) Herpes_UL31 PF02718.9 EKE41437.1 - 0.1 11.2 1.4 2.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL31-like protein DicB PF05358.6 EKE41437.1 - 1.6 8.2 4.6 0.65 9.5 0.2 2.1 2 0 0 2 2 2 0 DicB protein DNA_topoisoIV PF00521.15 EKE41438.1 - 0.14 10.9 4.6 0.19 10.5 3.2 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A adh_short PF00106.20 EKE41439.1 - 4e-23 82.1 0.0 4.9e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKE41439.1 - 1.7e-08 34.5 0.0 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKE41439.1 - 4.1e-06 26.5 0.0 8.4e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EKE41439.1 - 3.2e-05 22.9 0.2 4.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EKE41439.1 - 0.0043 17.4 0.3 0.0074 16.6 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EKE41439.1 - 0.0044 16.4 0.3 0.021 14.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EKE41439.1 - 0.0055 15.9 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKE41439.1 - 0.0057 16.6 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding ResIII PF04851.10 EKE41439.1 - 0.0066 16.3 0.1 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit 3HCDH_N PF02737.13 EKE41439.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PepSY_TM_2 PF13703.1 EKE41439.1 - 0.028 14.5 0.5 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 PepSY-associated TM helix Saccharop_dh PF03435.13 EKE41439.1 - 0.029 13.3 0.1 0.038 12.9 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EKE41439.1 - 0.04 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EKE41439.1 - 0.076 13.4 0.2 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Got1 PF04178.7 EKE41440.1 - 0.84 9.7 17.6 2 8.5 12.2 1.7 1 1 0 1 1 1 0 Got1/Sft2-like family PRA1 PF03208.14 EKE41440.1 - 4.8 6.5 8.0 31 3.8 5.1 2.1 1 1 1 2 2 2 0 PRA1 family protein DUF2385 PF09539.5 EKE41441.1 - 0.11 12.9 1.5 26 5.2 1.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2385) Sigma_1_2 PF03084.9 EKE41441.1 - 0.17 10.5 1.6 0.17 10.5 0.1 1.7 2 1 0 2 2 2 0 Reoviral Sigma1/Sigma2 family Phage_holin_1 PF04531.8 EKE41441.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.2 2 1 0 2 2 2 0 Bacteriophage holin FNIP_N PF14636.1 EKE41441.1 - 0.32 11.4 4.0 0.089 13.2 0.5 1.8 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Vma12 PF11712.3 EKE41441.1 - 0.33 10.6 11.0 0.076 12.7 1.5 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Phyto_Pns9_10 PF05878.6 EKE41441.1 - 1.6 7.6 6.9 2.6 6.9 4.8 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF19 PF01579.13 EKE41441.1 - 1.7 8.5 8.9 7 6.6 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF19) Neur_chan_memb PF02932.11 EKE41441.1 - 2.2 8.1 8.4 4.9 6.9 1.4 2.4 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RP-C_C PF11800.3 EKE41441.1 - 2.7 7.6 8.3 4.6 6.8 5.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region S1 PF00575.18 EKE41442.1 - 0.061 13.4 0.3 0.21 11.7 0.2 1.9 1 0 0 1 1 1 0 S1 RNA binding domain AnfG_VnfG PF03139.10 EKE41443.1 - 0.055 13.2 1.2 0.42 10.4 0.0 2.7 2 1 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit DUF972 PF06156.8 EKE41443.1 - 1.6 9.1 6.5 3.2 8.1 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) eIF-5a PF01287.15 EKE41443.1 - 7.5 6.5 8.5 0.93 9.4 0.5 3.0 4 0 0 4 4 4 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Helicase_C PF00271.26 EKE41446.1 - 1.6e-11 43.8 0.2 2e-10 40.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.18 EKE41446.1 - 3.1e-11 43.2 0.0 6.7e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 EKE41446.1 - 8e-08 31.9 2.1 9.2e-08 31.7 0.1 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EKE41446.1 - 1.4e-06 28.1 0.1 3.4e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EKE41446.1 - 0.00012 22.2 0.2 0.00049 20.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKE41446.1 - 0.0022 17.2 0.0 0.0056 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EKE41446.1 - 0.0029 17.4 1.1 0.062 13.2 0.8 2.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EKE41446.1 - 0.0037 17.5 3.3 0.017 15.3 0.0 3.0 2 1 0 3 3 3 1 ABC transporter KaiC PF06745.8 EKE41446.1 - 0.0071 15.4 0.1 0.065 12.3 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_23 PF13476.1 EKE41446.1 - 0.013 15.7 0.6 0.013 15.7 0.4 3.3 2 2 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EKE41446.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EKE41446.1 - 0.015 15.7 0.0 0.082 13.4 0.0 2.3 1 0 0 1 1 1 0 Miro-like protein UPF0079 PF02367.12 EKE41446.1 - 0.028 14.0 0.0 0.086 12.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EKE41446.1 - 0.038 13.5 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.10 EKE41446.1 - 0.042 13.6 9.0 0.024 14.4 0.7 3.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 EKE41446.1 - 0.078 13.1 1.1 0.3 11.2 0.1 2.5 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE41446.1 - 0.17 11.8 0.0 0.48 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_C1 PF00112.18 EKE41447.1 - 3.3e-70 236.4 3.6 4.1e-70 236.0 2.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE41447.1 - 1.3e-05 25.3 2.1 2.7e-05 24.3 1.5 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKE41447.1 - 0.00077 18.1 0.1 0.044 12.2 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family AAA_23 PF13476.1 EKE41448.1 - 7.5e-17 62.3 13.8 7.5e-17 62.3 9.6 6.6 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.14 EKE41448.1 - 1.6e-14 53.6 0.4 1.6e-14 53.6 0.3 3.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKE41448.1 - 3.7e-06 27.1 2.8 3.7e-06 27.1 2.0 5.3 1 1 3 4 4 4 1 AAA domain AAA_29 PF13555.1 EKE41448.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EKE41448.1 - 0.023 14.5 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EKE41448.1 - 0.045 13.1 0.0 0.18 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKE41448.1 - 0.17 12.1 0.0 0.17 12.1 0.0 5.8 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 EKE41448.1 - 0.59 8.5 115.8 0.39 9.1 22.8 5.2 3 2 2 5 5 5 0 AAA domain TLD PF07534.11 EKE41449.1 - 0.00076 19.4 0.9 0.002 18.1 0.6 1.7 1 0 0 1 1 1 1 TLD CAF-1_p150 PF11600.3 EKE41449.1 - 0.0013 18.2 65.2 0.0021 17.4 45.2 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 EKE41449.1 - 1.2 8.9 34.9 2 8.2 24.2 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2413 PF10310.4 EKE41449.1 - 9.1 4.9 33.5 15 4.2 23.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Borrelia_P83 PF05262.6 EKE41449.1 - 10 4.2 35.5 13 3.8 24.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein tRNA-synt_1 PF00133.17 EKE41450.1 - 2.9e-207 689.3 1.2 2.9e-207 689.3 0.9 3.0 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EKE41450.1 - 9.1e-40 135.9 0.1 9.1e-40 135.9 0.1 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EKE41450.1 - 3.6e-15 55.5 19.2 1.6e-08 33.6 0.2 6.1 4 1 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EKE41450.1 - 7.8e-08 31.8 0.0 7.8e-08 31.8 0.0 3.0 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 DUF3300 PF11737.3 EKE41450.1 - 0.017 14.3 1.5 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) MRP-S35 PF10246.4 EKE41450.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 TPR_11 PF13414.1 EKE41451.1 - 7.9e-24 83.0 16.5 5.5e-07 29.1 0.1 7.1 7 0 0 7 7 7 5 TPR repeat TPR_2 PF07719.12 EKE41451.1 - 5.3e-11 41.5 26.1 0.12 12.3 0.0 10.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.1 EKE41451.1 - 3.8e-09 36.3 18.1 0.00019 21.2 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41451.1 - 1e-07 32.4 0.9 0.035 14.7 0.0 5.5 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EKE41451.1 - 2.5e-07 30.9 9.4 1.6 9.1 0.1 8.1 7 3 2 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41451.1 - 2.9e-07 30.1 4.6 1.8e-05 24.5 0.0 5.4 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKE41451.1 - 1.7e-05 24.2 38.9 0.021 14.4 0.3 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EKE41451.1 - 0.00032 20.2 4.1 0.71 9.8 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41451.1 - 0.00094 18.7 0.0 0.00094 18.7 0.0 7.9 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKE41451.1 - 0.0043 17.5 1.8 0.11 13.1 0.0 4.3 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKE41451.1 - 0.008 16.0 2.7 6.3 6.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Peptidase_C1 PF00112.18 EKE41452.1 - 1.6e-65 221.0 6.0 1.6e-65 221.0 4.2 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE41452.1 - 2.4e-09 37.2 0.3 6.5e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKE41452.1 - 9.5e-05 21.0 3.1 0.1 11.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF870 PF05912.6 EKE41452.1 - 0.0014 18.4 0.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 Caenorhabditis elegans protein of unknown function (DUF870) DUF1732 PF08340.6 EKE41452.1 - 0.078 12.8 0.3 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Aminotran_1_2 PF00155.16 EKE41453.1 - 4.2e-42 144.3 0.0 5.5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKE41453.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase EST1_DNA_bind PF10373.4 EKE41454.1 - 3 6.9 9.4 0.43 9.7 3.3 1.9 3 1 0 3 3 3 0 Est1 DNA/RNA binding domain Hexapep PF00132.19 EKE41455.1 - 6.5e-16 57.0 22.4 4.5e-11 41.7 2.2 4.2 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKE41455.1 - 2.4e-13 49.3 19.7 2.4e-08 33.3 1.0 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EKE41455.1 - 0.0018 18.2 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase IBR PF01485.16 EKE41456.1 - 4e-15 55.4 24.7 9.8e-11 41.3 1.8 4.7 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EKE41456.1 - 2.2e-06 27.5 8.4 2.2e-06 27.5 5.8 4.5 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE41456.1 - 0.00029 20.4 4.5 0.00029 20.4 3.1 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE41456.1 - 0.00083 19.1 10.1 0.00083 19.1 7.0 4.2 2 2 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EKE41456.1 - 0.015 14.9 7.5 0.015 14.9 5.2 4.5 3 2 2 5 5 5 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKE41456.1 - 0.018 14.7 14.2 0.018 14.7 9.8 4.6 2 2 2 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 EKE41456.1 - 0.49 9.9 25.4 0.91 9.0 0.4 3.6 3 0 0 3 3 3 0 Transposase zinc-binding domain Copine PF07002.11 EKE41457.1 - 1.9e-39 134.7 0.0 3.3e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EKE41457.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EKE41457.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Latarcin PF10279.4 EKE41458.1 - 0.011 15.9 0.1 0.39 10.9 0.0 2.5 1 1 1 2 2 2 0 Latarcin precursor AlaDh_PNT_C PF01262.16 EKE41458.1 - 4.5 6.8 7.9 0.7 9.4 1.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain VWA_2 PF13519.1 EKE41459.1 - 1.9e-07 31.3 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EKE41459.1 - 5.2e-07 29.0 0.0 8.3e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.1 EKE41459.1 - 5.6e-05 22.8 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EKE41459.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus ACDC PF14733.1 EKE41460.1 - 0.012 15.7 1.0 0.016 15.3 0.7 1.2 1 0 0 1 1 1 0 AP2-coincident C-terminal DUF2454 PF10521.4 EKE41460.1 - 0.11 11.4 0.2 0.13 11.2 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2454) Inhibitor_I48 PF10467.4 EKE41460.1 - 0.12 12.2 0.1 11 5.9 0.0 2.1 1 1 0 2 2 2 0 Peptidase inhibitor clitocypin ELFV_dehydrog PF00208.16 EKE41461.1 - 4.8e-34 118.0 0.4 1.3e-33 116.6 0.3 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EKE41461.1 - 2.2e-18 65.2 0.0 9.8e-12 43.1 0.0 3.1 3 0 0 3 3 3 3 Bacterial NAD-glutamate dehydrogenase Pkinase PF00069.20 EKE41462.1 - 4e-39 134.3 0.9 5.5e-39 133.8 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41462.1 - 4.4e-24 84.9 0.1 6.6e-24 84.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKE41462.1 - 1.8e-06 27.9 0.4 5.9e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EKE41462.1 - 8.1e-06 24.9 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EKE41465.1 - 2.3e-54 184.2 0.1 4.4e-54 183.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41465.1 - 2.6e-19 69.2 0.1 4.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41465.1 - 0.00048 19.1 0.0 0.00079 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EKE41465.1 - 0.0039 16.7 0.6 0.013 15.0 0.4 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase PIP49_C PF12260.3 EKE41465.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 APH PF01636.18 EKE41465.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EKE41465.1 - 0.014 14.7 0.0 0.014 14.7 0.0 1.9 3 0 0 3 3 3 0 RIO1 family YrbL-PhoP_reg PF10707.4 EKE41465.1 - 0.056 12.7 0.5 1.6 8.0 0.0 2.3 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL DUF973 PF06157.6 EKE41466.1 - 0.041 12.8 5.8 0.037 12.9 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF624 PF04854.9 EKE41466.1 - 0.049 13.4 1.3 0.68 9.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF624 MARVEL PF01284.18 EKE41466.1 - 0.1 12.4 7.9 0.41 10.4 4.9 2.1 1 1 0 1 1 1 0 Membrane-associating domain DUF3165 PF11364.3 EKE41466.1 - 0.12 12.5 3.9 0.098 12.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) Adeno_E3_14_5 PF04834.7 EKE41466.1 - 0.3 11.5 5.5 16 6.0 0.6 3.0 3 0 0 3 3 3 0 Early E3 14.5 kDa protein DUF4293 PF14126.1 EKE41466.1 - 0.31 10.9 5.6 0.5 10.2 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) O-antigen_lig PF13425.1 EKE41466.1 - 0.68 9.9 10.1 3.6 7.5 4.1 2.5 2 1 1 3 3 3 0 O-antigen ligase like membrane protein DUF3139 PF11337.3 EKE41466.1 - 0.93 9.8 0.0 0.93 9.8 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3139) Nucleoplasmin PF03066.10 EKE41468.1 - 0.0011 18.5 0.1 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 1 Nucleoplasmin DUF2963 PF11178.3 EKE41469.1 - 0.11 11.9 3.3 0.38 10.2 2.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2963) Rho_GDI PF02115.12 EKE41470.1 - 1.3e-37 129.2 0.1 1.5e-37 128.9 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor BRCT PF00533.21 EKE41471.1 - 7.2e-16 58.1 0.8 4.4e-08 33.1 0.1 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKE41471.1 - 2.8e-08 33.4 0.0 3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 twin BRCT domain DUF3185 PF11381.3 EKE41471.1 - 0.0088 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3185) Arm PF00514.18 EKE41472.1 - 0.0035 17.1 6.0 1.6 8.6 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat TAXi_C PF14541.1 EKE41472.1 - 0.035 13.6 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal HTH_Tnp_1 PF01527.15 EKE41473.1 - 0.0097 15.8 0.1 0.72 9.8 0.1 2.3 1 1 0 1 1 1 1 Transposase A2M_recep PF07677.9 EKE41474.1 - 0.079 13.1 0.3 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 A-macroglobulin receptor Astro_capsid PF03115.9 EKE41474.1 - 0.098 10.8 1.2 0.12 10.5 0.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SNF2_N PF00176.18 EKE41477.1 - 5.7e-65 219.0 1.3 1.2e-64 217.9 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE41477.1 - 5.6e-15 54.9 0.0 3e-14 52.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Exonuc_VII_L PF02601.10 EKE41477.1 - 3.6 6.7 13.6 7.4 5.6 9.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Clathrin PF00637.15 EKE41478.1 - 2.2e-168 552.5 69.2 2.4e-31 108.2 5.3 8.5 8 1 1 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EKE41478.1 - 2.4e-25 88.2 0.3 2.4e-25 88.2 0.2 2.8 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.15 EKE41478.1 - 8.7e-10 38.2 1.5 0.00094 19.3 0.0 5.1 4 0 0 4 4 4 2 Clathrin propeller repeat TPR_14 PF13428.1 EKE41478.1 - 4.3e-07 30.0 4.9 1.9 9.3 0.0 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat Clathrin-link PF09268.5 EKE41478.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.6 1 0 0 1 1 1 0 Clathrin, heavy-chain linker TPR_7 PF13176.1 EKE41478.1 - 0.03 14.1 11.8 2.8 7.9 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKE41478.1 - 0.078 13.4 3.8 48 4.7 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Helicase_C PF00271.26 EKE41479.1 - 5.4e-16 58.2 0.0 1.9e-15 56.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 EKE41479.1 - 2.4e-13 49.9 0.0 2.4e-13 49.9 0.0 3.7 4 2 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EKE41479.1 - 1.5e-11 44.1 0.0 5.7e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EKE41479.1 - 1.7e-11 43.8 0.4 7e-11 41.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE41479.1 - 5.6e-05 23.2 0.3 5.6e-05 23.2 0.2 2.4 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EKE41479.1 - 0.12 11.7 0.0 0.35 10.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.18 EKE41480.1 - 1.8e-34 119.5 5.4 3.8e-34 118.4 3.7 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE41480.1 - 5.7e-13 48.9 0.7 1.6e-12 47.4 0.5 1.8 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) RasGEF PF00617.14 EKE41481.1 - 7.5e-39 133.4 6.3 1.6e-38 132.3 4.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE41481.1 - 0.00028 20.9 0.2 0.00028 20.9 0.2 3.7 4 0 0 4 4 4 1 RasGEF N-terminal motif Brix PF04427.13 EKE41482.1 - 2.7e-45 154.3 1.1 3.4e-45 154.0 0.7 1.1 1 0 0 1 1 1 1 Brix domain Cnd2 PF05786.9 EKE41483.1 - 9.3e-23 80.6 4.9 1.1e-22 80.4 3.4 1.3 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF2441 PF10386.4 EKE41483.1 - 0.0041 17.1 0.1 0.0074 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2441) zf-DBF PF07535.7 EKE41483.1 - 1.7 8.4 5.6 0.65 9.7 1.4 2.1 2 0 0 2 2 2 0 DBF zinc finger OCD_Mu_crystall PF02423.10 EKE41484.1 - 6.2e-36 123.7 0.0 7.7e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DUF912 PF06024.7 EKE41485.1 - 0.0059 16.6 0.3 0.022 14.8 0.2 2.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1180 PF06679.7 EKE41485.1 - 0.044 13.6 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GRDB PF07355.7 EKE41486.1 - 0.028 13.3 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Glyco_hydro_3 PF00933.16 EKE41488.1 - 5.7e-65 219.2 0.0 8.3e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKE41488.1 - 5.3e-34 117.7 0.0 2e-33 115.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKE41488.1 - 5.5e-17 61.4 0.0 1.2e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain TLD PF07534.11 EKE41489.1 - 7.8e-05 22.6 1.5 9e-05 22.4 1.0 1.1 1 0 0 1 1 1 1 TLD Laminin_II PF06009.7 EKE41490.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Laminin Domain II OEP PF02321.13 EKE41490.1 - 0.027 14.0 0.6 0.031 13.8 0.4 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DegQ PF08181.6 EKE41490.1 - 0.064 12.9 1.6 0.15 11.7 0.9 1.8 1 1 0 1 1 1 0 DegQ (SacQ) family CheZ PF04344.8 EKE41490.1 - 0.072 12.7 0.4 0.099 12.2 0.3 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Syntaxin-6_N PF09177.6 EKE41490.1 - 0.092 13.1 1.3 0.11 12.9 0.4 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal NDUF_B6 PF09782.4 EKE41490.1 - 0.093 12.5 0.6 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit HrcA PF01628.16 EKE41490.1 - 0.098 12.2 0.3 0.15 11.6 0.2 1.4 1 1 0 1 1 1 0 HrcA protein C terminal domain IncA PF04156.9 EKE41490.1 - 0.23 11.0 3.0 0.27 10.8 2.1 1.1 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EKE41490.1 - 0.37 9.1 3.6 0.41 8.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CoaE PF01121.15 EKE41492.1 - 3.8e-35 120.9 0.1 4.4e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EKE41492.1 - 2.6e-06 28.2 1.5 6.3e-06 27.0 1.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE41492.1 - 0.00024 21.4 2.7 0.0012 19.1 1.9 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EKE41492.1 - 0.00095 19.1 0.1 0.0015 18.4 0.1 1.4 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.1 EKE41492.1 - 0.028 14.2 0.1 0.091 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKE41492.1 - 0.031 14.5 2.4 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EKE41492.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phage_Cox PF10743.4 EKE41492.1 - 0.1 12.6 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Regulatory phage protein cox MMR_HSR1 PF01926.18 EKE41492.1 - 0.29 11.1 2.0 0.34 10.8 0.2 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Vps51 PF08700.6 EKE41493.1 - 0.00018 21.2 0.8 0.00018 21.2 0.6 3.8 6 0 0 6 6 6 1 Vps51/Vps67 Cyanate_lyase PF02560.9 EKE41493.1 - 0.028 13.9 0.4 0.43 10.1 0.0 2.9 3 0 0 3 3 3 0 Cyanate lyase C-terminal domain DUF1844 PF08899.6 EKE41493.1 - 0.042 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Synaptonemal_3 PF15191.1 EKE41493.1 - 0.07 12.8 5.1 5.5 6.7 0.1 3.9 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 DUF3052 PF11253.3 EKE41493.1 - 0.071 12.7 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) NT-C2 PF10358.4 EKE41495.1 - 9.7e-10 38.1 1.1 2.8e-09 36.6 0.7 1.7 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EKE41495.1 - 3.9e-06 26.6 3.3 7.7e-06 25.7 0.6 2.5 2 0 0 2 2 2 1 DIL domain DUF1712 PF08217.6 EKE41496.1 - 3.8e-09 35.3 3.3 7.4e-09 34.4 2.3 1.6 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF2179 PF10035.4 EKE41497.1 - 0.078 12.5 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Acyltransferase PF01553.16 EKE41498.1 - 1e-13 50.8 0.0 1.6e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CAF1 PF04857.15 EKE41498.1 - 0.12 11.6 0.5 0.58 9.4 0.1 2.0 2 0 0 2 2 2 0 CAF1 family ribonuclease TLD PF07534.11 EKE41499.1 - 2.5e-05 24.3 0.3 4.4e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 TLD PfUIS3 PF11567.3 EKE41499.1 - 0.022 14.9 2.5 0.026 14.6 0.7 1.9 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein DUF4463 PF14703.1 EKE41499.1 - 0.06 13.8 6.3 0.17 12.3 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Rap_GAP PF02145.10 EKE41500.1 - 1.9e-52 177.3 0.0 4.2e-52 176.2 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Herpes_UL92 PF03048.9 EKE41500.1 - 1.3 8.5 14.1 0.42 10.1 0.5 3.3 4 0 0 4 4 4 0 UL92 family DnaJ PF00226.26 EKE41501.1 - 2.6e-05 23.8 0.0 5.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PNP_UDP_1 PF01048.15 EKE41502.1 - 2.4e-40 137.9 0.2 2.9e-40 137.7 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4131 PF13567.1 EKE41503.1 - 4.6 6.6 6.4 3.7 6.9 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.17 EKE41504.1 - 2.4e-18 65.4 2.7 8e-11 41.4 0.2 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41504.1 - 6.9e-16 57.8 0.5 4.1e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41504.1 - 4.5e-07 29.7 0.2 0.00062 19.7 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKE41504.1 - 0.19 11.5 3.8 0.51 10.2 0.0 3.1 4 0 0 4 4 4 0 RNA binding motif RhoGEF PF00621.15 EKE41505.1 - 1.3e-16 61.0 18.3 2.8e-16 59.9 12.7 1.7 1 0 0 1 1 1 1 RhoGEF domain Neuroparsin PF07327.6 EKE41505.1 - 0.037 14.2 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Neuroparsin BAG PF02179.11 EKE41505.1 - 0.2 11.7 0.1 0.2 11.7 0.1 4.5 4 0 0 4 4 4 0 BAG domain DUF2533 PF10752.4 EKE41505.1 - 2.8 8.3 10.1 3.3 8.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2533) CTP_transf_2 PF01467.21 EKE41506.1 - 1.2e-25 90.4 0.1 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DUF288 PF03385.12 EKE41506.1 - 0.062 11.7 5.4 3.9 5.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function, DUF288 UCH PF00443.24 EKE41507.1 - 2.9e-26 92.1 12.2 2.9e-26 92.1 8.5 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE41507.1 - 9.8e-08 31.7 13.6 2.8e-06 27.0 9.5 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Geminin PF07412.7 EKE41508.1 - 0.0006 19.5 5.6 0.0008 19.1 3.9 1.3 1 0 0 1 1 1 1 Geminin DUF4201 PF13870.1 EKE41508.1 - 0.0068 15.8 6.7 0.009 15.4 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF904 PF06005.7 EKE41508.1 - 0.024 14.9 6.6 0.046 14.0 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF641 PF04859.7 EKE41508.1 - 0.034 13.8 4.8 0.05 13.3 3.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.4 EKE41508.1 - 0.046 13.5 9.7 0.073 12.9 6.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3782 PF12644.2 EKE41508.1 - 0.069 12.9 2.3 0.17 11.7 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) CCDC-167 PF15188.1 EKE41508.1 - 0.072 13.0 4.2 0.16 11.9 2.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Phage_GP20 PF06810.6 EKE41508.1 - 0.09 12.2 12.9 0.037 13.4 6.8 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 Jacalin PF01419.12 EKE41508.1 - 0.09 12.6 1.0 0.13 12.1 0.4 1.5 1 1 0 1 1 1 0 Jacalin-like lectin domain APG6 PF04111.7 EKE41508.1 - 0.095 11.7 6.6 0.096 11.7 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spectrin PF00435.16 EKE41508.1 - 0.11 12.8 3.9 0.15 12.3 2.7 1.3 1 0 0 1 1 1 0 Spectrin repeat Macoilin PF09726.4 EKE41508.1 - 0.11 10.7 6.7 0.13 10.5 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 EKE41508.1 - 0.13 11.1 4.7 0.16 10.8 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 EKE41508.1 - 0.15 11.8 9.7 0.22 11.3 6.8 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain TLE_N PF03920.10 EKE41508.1 - 0.17 11.6 4.3 0.24 11.2 3.0 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DivIC PF04977.10 EKE41508.1 - 0.23 10.9 6.8 0.42 10.1 4.6 1.5 1 1 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 EKE41508.1 - 0.27 9.0 4.5 0.25 9.1 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EKE41508.1 - 0.32 11.3 6.3 0.37 11.1 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EKE41508.1 - 0.35 10.4 5.6 0.4 10.2 3.9 1.2 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 EKE41508.1 - 0.48 9.8 7.1 0.7 9.3 4.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like OmpH PF03938.9 EKE41508.1 - 0.86 9.5 6.5 1.1 9.1 4.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.13 EKE41508.1 - 8.6 6.1 13.5 1.6 8.4 5.4 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper UPF0183 PF03676.9 EKE41509.1 - 3e-25 88.6 8.5 4.8e-18 64.9 4.4 2.3 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Z1 PF10593.4 EKE41509.1 - 0.017 14.3 0.1 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Z1 domain Peptidase_M9 PF01752.12 EKE41509.1 - 0.053 12.4 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Collagenase Pkinase PF00069.20 EKE41510.1 - 9.4e-60 201.9 0.1 3.5e-59 200.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41510.1 - 1.7e-34 119.0 0.0 3.4e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 EKE41510.1 - 5.3e-17 61.6 0.2 2e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 PX domain PH PF00169.24 EKE41510.1 - 2.9e-12 46.7 0.4 1.6e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 EKE41510.1 - 4.4e-06 25.8 0.0 7.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE41510.1 - 0.0001 22.1 0.0 0.033 13.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family PH_11 PF15413.1 EKE41510.1 - 0.0016 18.6 0.1 0.0068 16.6 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain HTH_3 PF01381.17 EKE41511.1 - 2.4e-17 62.5 0.7 3.7e-17 61.9 0.5 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EKE41511.1 - 5.1e-09 36.1 0.1 1.1e-08 35.1 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EKE41511.1 - 1.8e-07 31.0 0.2 2.9e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 EKE41511.1 - 0.0099 15.6 0.3 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 EKE41511.1 - 0.01 15.3 0.2 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MitMem_reg PF13012.1 EKE41511.1 - 0.032 14.2 0.3 0.046 13.7 0.2 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function HTH_24 PF13412.1 EKE41511.1 - 0.087 12.2 0.1 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding WD40 PF00400.27 EKE41512.1 - 3.5e-05 23.5 0.1 0.52 10.2 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Sipho_tail PF05709.6 EKE41512.1 - 0.021 13.9 0.5 0.21 10.7 0.4 2.1 1 1 0 1 1 1 0 Phage tail protein BBS2_Mid PF14783.1 EKE41512.1 - 0.14 11.9 3.9 1.8 8.3 0.0 3.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DctQ PF04290.7 EKE41513.1 - 1.6 8.4 8.1 0.29 10.9 2.8 1.8 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component HEAT PF02985.17 EKE41514.1 - 1.6e-08 33.8 4.5 0.00091 19.1 0.1 5.1 5 0 0 5 5 5 2 HEAT repeat WD40 PF00400.27 EKE41514.1 - 3.9e-07 29.7 0.3 0.013 15.3 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Cnd1 PF12717.2 EKE41514.1 - 0.00016 21.5 0.4 0.037 13.8 0.1 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EKE41514.1 - 0.00081 19.6 0.1 0.0098 16.1 0.0 2.7 2 1 0 2 2 2 1 HEAT repeats V-ATPase_H_C PF11698.3 EKE41514.1 - 0.0042 16.9 0.1 1.1 9.1 0.1 2.7 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_EZ PF13513.1 EKE41514.1 - 0.37 11.3 2.7 0.96 10.0 0.2 3.0 2 2 1 3 3 3 0 HEAT-like repeat PAP2_C PF14360.1 EKE41515.1 - 4.9e-11 42.7 13.5 3.9e-09 36.6 9.4 2.2 1 1 0 1 1 1 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EKE41515.1 - 0.00042 20.0 4.2 0.00057 19.5 2.9 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EKE41515.1 - 0.027 14.0 0.4 0.027 14.0 0.3 2.1 2 0 0 2 2 2 0 PAP2 superfamily DUF3270 PF11674.3 EKE41515.1 - 0.073 13.0 1.9 0.13 12.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Ras PF00071.17 EKE41516.1 - 8e-18 64.3 0.2 1.3e-17 63.6 0.2 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKE41516.1 - 2.2e-09 37.8 1.1 3.7e-08 33.8 0.1 2.4 2 1 1 3 3 2 1 Miro-like protein MMR_HSR1 PF01926.18 EKE41516.1 - 2.4e-09 37.1 0.0 5.9e-09 35.8 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKE41516.1 - 1.4e-08 34.7 2.5 3.6e-07 30.1 1.7 2.8 1 1 0 1 1 1 1 Dynamin family AIG1 PF04548.11 EKE41516.1 - 2.3e-07 30.1 0.4 2.9e-06 26.5 0.0 2.5 1 1 2 3 3 3 1 AIG1 family Gtr1_RagA PF04670.7 EKE41516.1 - 4.6e-06 25.9 0.3 7.8e-06 25.1 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE41516.1 - 6e-06 25.5 0.2 9.3e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKE41516.1 - 1.1e-05 24.9 0.0 0.019 14.4 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EKE41516.1 - 6.6e-05 22.1 0.8 0.00099 18.3 0.0 2.9 3 1 0 3 3 3 1 Protein of unknown function, DUF258 Arf PF00025.16 EKE41516.1 - 0.00021 20.5 0.0 0.0003 20.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EKE41516.1 - 0.00045 19.5 0.0 0.00074 18.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 EKE41516.1 - 0.0014 17.7 0.0 0.0048 15.9 0.0 1.9 2 0 0 2 2 2 1 Septin AAA_10 PF12846.2 EKE41516.1 - 0.0048 16.3 0.1 0.042 13.2 0.0 2.0 1 1 0 2 2 2 1 AAA-like domain ATP_bind_1 PF03029.12 EKE41516.1 - 0.0071 15.9 1.6 0.46 9.9 0.3 2.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EKE41516.1 - 0.0096 15.6 0.1 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 EKE41516.1 - 0.012 15.0 0.1 0.092 12.1 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EKE41516.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.16 EKE41516.1 - 0.033 13.6 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase PduV-EutP PF10662.4 EKE41516.1 - 0.041 13.3 0.1 0.89 9.0 0.0 2.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EKE41516.1 - 0.053 13.5 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EKE41516.1 - 0.053 13.4 0.1 0.11 12.3 0.1 1.8 1 1 1 2 2 2 0 AAA domain CPT PF07931.7 EKE41516.1 - 0.062 12.9 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 EKE41516.1 - 0.18 12.1 2.5 1.2 9.4 1.7 2.5 1 1 0 1 1 1 0 AAA domain Cactin_mid PF10312.4 EKE41517.1 - 0.038 13.2 1.6 0.067 12.4 1.1 1.4 1 0 0 1 1 1 0 Conserved mid region of cactin RhoGEF PF00621.15 EKE41519.1 - 1.1e-25 90.5 1.0 1.5e-25 90.0 0.7 1.2 1 0 0 1 1 1 1 RhoGEF domain IQ PF00612.22 EKE41519.1 - 0.00041 19.7 0.2 0.001 18.4 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.24 EKE41519.1 - 0.016 15.4 0.1 0.037 14.2 0.1 1.7 1 1 0 1 1 1 0 PH domain Brix PF04427.13 EKE41520.1 - 2e-30 105.8 1.6 3.5e-30 105.0 1.1 1.4 1 0 0 1 1 1 1 Brix domain Ndufs5 PF10200.4 EKE41520.1 - 0.15 12.0 2.3 5.3 7.1 1.4 2.5 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa RNR_N PF08343.5 EKE41520.1 - 1.1 9.1 6.0 17 5.3 4.2 2.6 1 1 0 1 1 1 0 Ribonucleotide reductase N-terminal Glyco_hydro_31 PF01055.21 EKE41521.1 - 1.2e-82 278.0 6.4 2e-82 277.3 4.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKE41521.1 - 8.1e-10 38.4 1.9 1.1e-08 34.8 1.1 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like EF-hand_7 PF13499.1 EKE41522.1 - 4.1e-07 30.0 0.4 1.3e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EKE41522.1 - 1.4e-05 24.0 2.0 0.00039 19.5 0.1 3.1 2 1 1 3 3 3 1 EF hand EF-hand_8 PF13833.1 EKE41522.1 - 4.5e-05 22.9 1.4 0.0037 16.8 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE41522.1 - 0.00028 20.4 0.7 0.0026 17.4 0.1 2.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EKE41522.1 - 0.002 17.4 1.0 0.0054 16.0 0.1 2.1 2 0 0 2 2 2 1 EF hand MtrA PF04208.9 EKE41522.1 - 0.035 13.5 0.2 0.075 12.4 0.1 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A RabGAP-TBC PF00566.13 EKE41523.1 - 2.3e-09 37.0 5.4 2.4e-08 33.7 3.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 EKE41523.1 - 2.9e-06 27.5 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S30 PF01577.11 EKE41523.1 - 0.21 10.9 3.5 0.39 10.0 2.4 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease TF_Zn_Ribbon PF08271.7 EKE41524.1 - 0.0024 17.1 0.5 0.0024 17.1 0.4 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding RRN7 PF11781.3 EKE41524.1 - 0.0071 15.8 0.1 0.0071 15.8 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 A2L_zn_ribbon PF08792.5 EKE41524.1 - 0.0094 15.3 2.5 0.025 14.0 1.7 1.7 1 0 0 1 1 1 1 A2L zinc ribbon domain DUF2723 PF11028.3 EKE41524.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) HD PF01966.17 EKE41525.1 - 0.00031 20.7 0.4 0.00082 19.3 0.1 1.9 1 1 1 2 2 2 1 HD domain PXT1 PF15214.1 EKE41525.1 - 0.00081 19.5 0.3 0.0026 17.9 0.1 1.9 2 0 0 2 2 2 1 Peroxisomal testis-specific protein 1 MbeB_N PF04837.7 EKE41525.1 - 0.033 14.2 0.1 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Ras PF00071.17 EKE41526.1 - 1.3e-18 66.9 0.3 1.7e-18 66.5 0.2 1.3 1 1 0 1 1 1 1 Ras family Arf PF00025.16 EKE41526.1 - 1.7e-09 37.1 0.2 2.3e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE41526.1 - 3.2e-08 34.0 0.3 1.1e-07 32.3 0.0 1.8 1 1 1 2 2 2 1 Miro-like protein Gal-bind_lectin PF00337.17 EKE41526.1 - 0.0072 15.6 0.2 0.0092 15.3 0.1 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Gtr1_RagA PF04670.7 EKE41526.1 - 0.011 14.9 1.2 0.014 14.5 0.8 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-DHHC PF01529.15 EKE41527.1 - 5.6e-35 120.2 22.0 5.6e-35 120.2 15.2 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase stn_TNFRSF12A PF12191.3 EKE41527.1 - 7.9 6.5 8.3 25 4.9 5.8 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF4234 PF14018.1 EKE41528.1 - 0.062 13.0 1.3 0.18 11.5 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) RasGEF PF00617.14 EKE41529.1 - 2.1e-38 131.9 1.1 2.1e-38 131.9 0.8 3.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE41529.1 - 2.9e-07 30.5 1.2 2.9e-07 30.5 0.9 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif HEAT_2 PF13646.1 EKE41530.1 - 7.2e-07 29.4 0.0 25 5.2 0.0 6.9 5 1 2 7 7 7 0 HEAT repeats HEAT PF02985.17 EKE41530.1 - 4.3e-06 26.3 1.1 8.3 6.7 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EKE41530.1 - 0.00011 22.6 0.0 14 6.3 0.0 7.0 6 1 1 8 8 8 1 HEAT-like repeat Arm PF00514.18 EKE41530.1 - 0.0006 19.5 3.2 25 4.9 0.0 6.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EKE41530.1 - 0.012 15.0 0.5 0.012 15.0 0.3 5.2 5 2 1 6 6 6 0 CLASP N terminal DUF2435 PF10363.4 EKE41530.1 - 0.017 14.9 5.7 0.059 13.2 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF2435) IBN_N PF03810.14 EKE41530.1 - 0.098 12.5 0.1 0.098 12.5 0.1 4.3 5 0 0 5 5 5 0 Importin-beta N-terminal domain LRR_8 PF13855.1 EKE41531.1 - 2 8.2 7.1 5.7 6.7 0.0 4.5 4 1 0 4 4 4 0 Leucine rich repeat OTU PF02338.14 EKE41532.1 - 2.1e-11 44.4 0.1 2e-10 41.3 0.0 2.2 1 1 0 2 2 2 1 OTU-like cysteine protease ubiquitin PF00240.18 EKE41532.1 - 0.0088 15.4 0.1 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family ThiF PF00899.16 EKE41533.1 - 4.9e-40 136.5 0.1 7.5e-40 135.9 0.0 1.3 1 1 0 1 1 1 1 ThiF family ELFV_dehydrog PF00208.16 EKE41533.1 - 0.0015 18.1 0.1 0.003 17.1 0.0 1.6 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EKE41533.1 - 0.0033 16.8 0.2 0.0052 16.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EKE41533.1 - 0.0039 17.2 0.2 0.011 15.8 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EKE41533.1 - 0.0041 16.1 0.1 0.0053 15.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EKE41533.1 - 0.0049 16.8 0.4 0.19 11.7 0.1 2.2 1 1 1 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 EKE41533.1 - 0.0071 16.5 0.0 0.014 15.6 0.0 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EKE41533.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EKE41533.1 - 0.063 12.3 0.3 0.093 11.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EKE41533.1 - 0.12 11.8 0.6 0.22 10.9 0.4 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FMN_red PF03358.10 EKE41534.1 - 2e-18 66.3 0.0 2.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EKE41534.1 - 1.6e-06 27.7 0.0 1.7e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EKE41534.1 - 0.0013 18.7 0.0 0.003 17.5 0.0 1.5 1 1 1 2 2 2 1 Flavodoxin domain GTP_EFTU PF00009.22 EKE41535.1 - 2.8e-64 216.0 0.0 3.9e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EKE41535.1 - 1.5e-37 127.7 0.0 4e-37 126.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EKE41535.1 - 5.7e-22 77.3 0.0 1.2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EKE41535.1 - 1.4e-12 47.2 0.0 3.7e-12 45.9 0.0 1.6 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EKE41535.1 - 3.5e-12 46.2 0.0 1.1e-11 44.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKE41535.1 - 1.9e-05 24.6 0.1 3.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.13 EKE41536.1 - 9.6e-10 38.3 0.0 6.8e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EKE41536.1 - 8.3e-05 22.8 0.2 0.00051 20.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EKE41536.1 - 0.00019 22.2 0.1 0.00091 20.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EKE41536.1 - 0.00033 20.5 0.2 0.0038 17.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKE41536.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EKE41536.1 - 0.019 13.8 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.5 EKE41536.1 - 0.019 14.1 0.0 0.048 12.8 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Arch_ATPase PF01637.13 EKE41536.1 - 0.035 13.8 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Aminoglyc_resit PF10706.4 EKE41536.1 - 0.039 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase SRP54 PF00448.17 EKE41536.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EKE41536.1 - 0.08 12.5 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EKE41536.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EKE41536.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EKE41536.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DENN PF02141.16 EKE41537.1 - 1.4e-09 37.9 0.4 1.4e-09 37.9 0.3 2.3 3 0 0 3 3 3 1 DENN (AEX-3) domain dDENN PF03455.14 EKE41537.1 - 5.2e-09 36.0 8.7 1.6e-08 34.4 6.0 1.9 1 0 0 1 1 1 1 dDENN domain LIM PF00412.17 EKE41537.1 - 0.0068 16.4 12.4 0.011 15.7 8.0 1.8 1 1 0 1 1 1 1 LIM domain uDENN PF03456.13 EKE41537.1 - 0.019 14.9 0.0 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 uDENN domain Sec66 PF09802.4 EKE41538.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Ribonuc_L-PSP PF01042.16 EKE41539.1 - 8.8e-41 138.4 0.0 9.8e-41 138.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP pRN1_helical PF13010.1 EKE41539.1 - 0.053 13.1 1.0 0.78 9.3 0.1 2.0 1 1 1 2 2 2 0 Primase helical domain HEAT_EZ PF13513.1 EKE41540.1 - 0.14 12.6 0.1 0.36 11.3 0.1 1.7 1 0 0 1 1 1 0 HEAT-like repeat MutS_V PF00488.16 EKE41541.1 - 2.6e-73 246.3 0.0 4.7e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EKE41541.1 - 4.8e-25 88.5 0.5 4.8e-25 88.5 0.4 1.9 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EKE41541.1 - 5.8e-06 26.4 1.5 1.9e-05 24.7 0.1 2.3 2 0 0 2 2 2 1 MutS domain II Serinc PF03348.10 EKE41543.1 - 3.1e-48 164.5 32.6 1e-44 152.9 22.6 2.0 1 1 0 1 1 1 1 Serine incorporator (Serinc) Pkinase PF00069.20 EKE41544.1 - 2.2e-70 236.8 0.5 8.6e-70 234.8 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41544.1 - 7.3e-57 192.3 0.2 2.5e-56 190.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41544.1 - 0.00013 21.0 0.0 0.00041 19.4 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKE41544.1 - 0.00013 21.1 0.1 0.00035 19.7 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE41544.1 - 0.0059 16.3 0.0 1.8 8.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family LRR_5 PF13306.1 EKE41545.1 - 8.8e-39 132.1 8.1 2.3e-20 72.6 0.5 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41545.1 - 1.1e-12 47.5 4.6 0.00027 20.6 0.4 3.4 1 1 2 3 3 3 3 Leucine rich repeat zf-Tim10_DDP PF02953.10 EKE41545.1 - 0.85 8.9 12.1 6.6 6.1 0.9 4.0 3 1 1 4 4 4 0 Tim10/DDP family zinc finger Furin-like PF00757.15 EKE41545.1 - 2 8.0 8.1 4 7.0 1.6 2.2 1 1 1 2 2 2 0 Furin-like cysteine rich region RasGAP PF00616.14 EKE41546.1 - 1.2e-16 60.9 5.1 1.2e-16 60.9 3.5 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CTP_transf_2 PF01467.21 EKE41549.1 - 5.3e-27 94.7 0.0 4e-15 56.1 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EKE41549.1 - 9.7e-07 28.5 0.6 0.027 14.0 0.2 2.7 2 2 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.10 EKE41549.1 - 0.031 13.0 0.0 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase SAP30_Sin3_bdg PF13867.1 EKE41551.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Utp14 PF04615.8 EKE41552.1 - 2.8 5.9 71.3 4.2 5.3 49.4 1.3 1 0 0 1 1 1 0 Utp14 protein EF-hand_1 PF00036.27 EKE41553.1 - 0.0013 17.8 4.6 0.0037 16.4 1.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EKE41553.1 - 0.0051 16.9 4.2 0.056 13.5 0.4 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EKE41553.1 - 0.0084 15.7 0.7 0.034 13.7 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EKE41553.1 - 0.015 15.1 2.1 0.015 15.1 1.5 3.7 4 0 0 4 4 4 0 EF-hand domain EF-hand_5 PF13202.1 EKE41553.1 - 1.1 8.6 8.8 0.045 13.1 1.0 2.5 3 0 0 3 3 3 0 EF hand DUF1547 PF07577.6 EKE41555.1 - 0.027 14.1 0.2 0.06 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) TMF_TATA_bd PF12325.3 EKE41555.1 - 0.35 10.6 8.6 0.18 11.5 0.7 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 EKE41555.1 - 0.61 10.2 6.8 2.2 8.4 0.1 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 EKE41555.1 - 1.3 8.9 5.5 6.9 6.5 3.8 2.0 1 1 1 2 2 2 0 Tropomyosin like bZIP_2 PF07716.10 EKE41555.1 - 2 8.2 10.0 2.6 7.9 1.4 2.5 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 EKE41555.1 - 2.3 8.2 6.0 15 5.6 0.9 2.5 2 0 0 2 2 2 0 bZIP transcription factor Malic_M PF03949.10 EKE41556.1 - 3.3e-65 220.1 0.1 4.3e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EKE41556.1 - 1.2e-17 64.0 1.1 3.4e-16 59.3 0.8 2.6 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain DEAD PF00270.24 EKE41557.1 - 1.5e-40 138.4 0.0 5.1e-40 136.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE41557.1 - 1.2e-23 82.6 0.6 1e-22 79.7 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE41557.1 - 0.00021 21.1 0.0 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EKE41557.1 - 0.00026 20.1 0.0 0.00026 20.1 0.0 2.2 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit GUCT PF08152.7 EKE41557.1 - 0.00028 20.7 0.0 0.00083 19.2 0.0 1.8 1 0 0 1 1 1 1 GUCT (NUC152) domain FDX-ACB PF03147.9 EKE41557.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain SNF2_N PF00176.18 EKE41557.1 - 0.076 11.7 0.0 0.21 10.3 0.0 1.7 1 1 1 2 2 2 0 SNF2 family N-terminal domain zf-UBR PF02207.15 EKE41559.1 - 3.5e-16 58.6 15.5 3.5e-16 58.6 10.7 4.1 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) NAD_binding_5 PF07994.7 EKE41559.1 - 0.22 10.9 3.6 0.46 9.9 2.5 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Prok-RING_4 PF14447.1 EKE41559.1 - 4.5 6.9 18.2 0.015 14.8 2.0 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 LRR_4 PF12799.2 EKE41560.1 - 1.1e-21 76.0 52.7 2.3e-07 30.2 2.4 5.3 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE41560.1 - 4.4e-18 64.7 54.8 2.1e-06 27.3 6.1 4.0 1 1 5 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EKE41560.1 - 2.8e-12 44.8 24.0 0.043 13.8 0.2 7.5 7 0 0 7 7 7 6 Leucine Rich Repeat LRR_7 PF13504.1 EKE41560.1 - 2.9e-06 26.5 24.8 0.17 12.2 0.3 7.1 6 0 0 6 6 6 3 Leucine rich repeat Pox_L5 PF04872.8 EKE41560.1 - 0.052 13.1 0.8 0.18 11.4 0.1 2.3 2 0 0 2 2 2 0 Poxvirus L5 protein family LRR_6 PF13516.1 EKE41560.1 - 0.23 11.6 25.6 1.9 8.7 1.6 6.5 7 0 0 7 7 7 0 Leucine Rich repeat Chitin_synth_2 PF03142.10 EKE41561.1 - 1.1 7.4 14.1 2.1 6.6 9.8 1.3 1 0 0 1 1 1 0 Chitin synthase NT-C2 PF10358.4 EKE41562.1 - 6.9e-21 74.2 1.1 6.9e-21 74.2 0.8 1.9 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Cortex-I_coil PF09304.5 EKE41562.1 - 8.6e-05 22.5 0.2 0.00017 21.5 0.1 1.5 1 0 0 1 1 1 1 Cortexillin I, coiled coil Occludin_ELL PF07303.8 EKE41562.1 - 0.0086 16.7 0.1 0.023 15.4 0.1 1.6 1 0 0 1 1 1 1 Occludin homology domain 5TM-5TMR_LYT PF07694.7 EKE41562.1 - 0.085 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Filamin PF00630.14 EKE41563.1 - 1.8e-34 118.3 5.3 2.3e-23 82.6 0.3 3.2 3 0 0 3 3 3 3 Filamin/ABP280 repeat YtkA PF13115.1 EKE41563.1 - 3e-05 24.3 0.1 0.4 11.0 0.0 3.2 3 0 0 3 3 3 2 YtkA-like Y_Y_Y PF07495.8 EKE41563.1 - 0.00011 21.8 0.7 0.0083 15.8 0.1 3.4 4 1 0 4 4 4 1 Y_Y_Y domain GPI-anchored PF10342.4 EKE41563.1 - 0.01 16.2 0.4 1.2 9.6 0.0 3.0 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_1 PF02369.11 EKE41563.1 - 0.029 14.2 0.1 0.84 9.5 0.0 2.7 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 1) PapC_N PF13954.1 EKE41563.1 - 0.044 13.3 1.4 2.9 7.4 0.0 2.8 3 0 0 3 3 3 0 PapC N-terminal domain DUF3244 PF11589.3 EKE41563.1 - 0.057 13.1 2.4 0.45 10.2 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3244) CarboxypepD_reg PF13620.1 EKE41563.1 - 0.087 12.8 0.0 6.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain SCRL PF06876.7 EKE41563.1 - 2.1 8.3 6.3 1 9.3 1.0 2.5 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein MBOAT PF03062.14 EKE41564.1 - 6.9e-27 94.4 30.4 6.9e-27 94.4 21.0 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family 5TM-5TMR_LYT PF07694.7 EKE41564.1 - 6 6.1 22.1 0.44 9.8 2.4 2.6 2 0 0 2 2 2 0 5TMR of 5TMR-LYT PEX11 PF05648.9 EKE41565.1 - 1.9e-14 53.4 0.2 5.9e-09 35.5 0.0 2.0 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) TLD PF07534.11 EKE41566.1 - 0.00024 21.1 1.2 0.001 19.0 0.8 2.2 1 1 0 1 1 1 1 TLD PI-PLC-X PF00388.14 EKE41567.1 - 3.4e-07 29.7 0.1 5.3e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain START PF01852.14 EKE41569.1 - 8.2e-06 25.2 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3581 PF12119.3 EKE41569.1 - 0.069 12.3 1.1 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) HrpE PF06188.7 EKE41570.1 - 0.012 15.3 0.1 4 7.1 0.1 2.3 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E VSG_B PF13206.1 EKE41570.1 - 0.21 10.6 2.0 0.34 10.0 1.4 1.3 1 1 0 1 1 1 0 Trypanosomal VSG domain DUF2670 PF10875.3 EKE41570.1 - 0.28 11.2 2.5 0.31 11.0 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2670) DUF3753 PF12575.3 EKE41570.1 - 1 9.2 0.0 1 9.2 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3753) PBP1_TM PF14812.1 EKE41570.1 - 1.5 9.1 9.9 4.1 7.7 6.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 EKE41570.1 - 8.5 4.0 8.1 15 3.3 5.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 EKE41570.1 - 9.3 5.8 17.9 17 5.0 12.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pmp3 PF01679.12 EKE41571.1 - 6.4e-18 64.2 13.1 7e-18 64.0 9.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.6 EKE41571.1 - 0.27 10.5 2.0 0.25 10.6 1.0 1.4 1 1 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Ribosomal_L44 PF00935.14 EKE41572.1 - 9.7e-34 115.2 16.7 1.3e-33 114.7 11.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 EKE41572.1 - 0.0026 17.5 0.6 0.0026 17.5 0.4 2.3 1 1 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like FAM74 PF15026.1 EKE41572.1 - 0.063 12.9 0.7 0.08 12.5 0.5 1.1 1 0 0 1 1 1 0 FAM74 protein DUF329 PF03884.9 EKE41572.1 - 6.2 6.4 8.1 12 5.5 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF329) VWA PF00092.23 EKE41573.1 - 0.0089 15.7 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF2372 PF10178.4 EKE41573.1 - 0.025 14.6 0.1 0.064 13.3 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2372) PFEMP PF03011.10 EKE41573.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 PFEMP DBL domain BRCT PF00533.21 EKE41574.1 - 0.0066 16.5 0.1 0.025 14.7 0.1 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MSV199 PF10553.4 EKE41574.1 - 0.015 15.2 2.6 0.026 14.3 1.3 1.7 1 1 0 1 1 1 0 MSV199 domain AHS2 PF02626.10 EKE41574.1 - 0.055 12.7 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 Myb_DNA-binding PF00249.26 EKE41575.1 - 2.3e-11 43.5 0.8 3.4e-11 43.0 0.6 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE41575.1 - 0.00028 20.9 0.3 0.00055 19.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MscS_TM PF12794.2 EKE41576.1 - 0.013 14.0 1.6 0.017 13.7 1.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SAP25 PF15476.1 EKE41576.1 - 0.024 14.1 0.3 0.033 13.7 0.2 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 DUF3671 PF12420.3 EKE41576.1 - 0.13 12.2 1.9 0.19 11.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function Sec7_N PF12783.2 EKE41577.1 - 0.0012 18.2 0.4 0.0036 16.7 0.0 1.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF128 PF01995.11 EKE41577.1 - 0.024 13.6 0.1 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF128 FAE1_CUT1_RppA PF08392.7 EKE41578.1 - 3.5e-106 354.5 0.0 4.4e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.10 EKE41578.1 - 1.8e-10 40.9 0.0 3.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.5 EKE41578.1 - 3.3e-10 39.8 0.0 7.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.14 EKE41578.1 - 1.2e-05 24.7 0.0 1.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 EKE41578.1 - 0.032 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1386 PF07138.6 EKE41580.1 - 0.054 12.6 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) FYVE PF01363.16 EKE41581.1 - 0.00026 20.7 12.1 0.00068 19.4 8.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Sec20 PF03908.8 EKE41582.1 - 5.3 6.8 13.9 0.58 9.9 5.1 2.5 1 1 0 2 2 2 0 Sec20 TrbI_Ftype PF09677.5 EKE41582.1 - 6.3 6.6 6.7 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) NYD-SP28_assoc PF14775.1 EKE41583.1 - 0.0029 17.2 9.7 0.0029 17.2 6.7 2.8 1 1 1 2 2 2 1 Sperm tail C-terminal domain DUF3375 PF11855.3 EKE41583.1 - 0.014 14.1 6.2 0.13 10.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3375) bZIP_2 PF07716.10 EKE41583.1 - 0.022 14.5 1.2 0.022 14.5 0.8 4.3 4 2 2 6 6 6 0 Basic region leucine zipper Mto2_bdg PF12808.2 EKE41583.1 - 0.031 14.3 11.1 0.59 10.2 0.4 3.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.13 EKE41583.1 - 0.065 12.9 23.7 0.27 10.9 7.2 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF724 PF05266.9 EKE41583.1 - 0.24 11.0 29.2 0.57 9.7 7.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Iron_permease PF04120.7 EKE41583.1 - 0.51 9.9 18.6 5.5 6.5 5.7 4.0 3 1 1 4 4 4 0 Low affinity iron permease SpecificRecomb PF10136.4 EKE41583.1 - 0.81 7.6 3.7 1 7.3 2.6 1.1 1 0 0 1 1 1 0 Site-specific recombinase Intimin_C PF07979.6 EKE41583.1 - 1.3 9.2 4.8 0.3 11.3 0.2 2.3 3 0 0 3 3 3 0 Intimin C-type lectin domain DUF1875 PF08961.5 EKE41583.1 - 1.5 8.0 18.3 0.099 11.9 3.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DOG1 PF14144.1 EKE41583.1 - 1.5 8.8 6.1 12 5.9 0.7 3.0 2 1 1 3 3 3 0 Seed dormancy control Herpes_BLRF2 PF05812.7 EKE41583.1 - 2.1 8.1 23.7 1.6 8.5 1.7 3.2 3 1 0 3 3 3 0 Herpesvirus BLRF2 protein DUF4140 PF13600.1 EKE41583.1 - 4.9 7.6 15.9 3.6 8.0 1.8 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 EKE41583.1 - 7.1 6.9 46.0 1.1 9.6 6.2 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Pkinase PF00069.20 EKE41584.1 - 1.2e-53 181.8 0.2 2.2e-53 181.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41584.1 - 1.1e-50 172.1 0.1 2.5e-50 170.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase VSP PF03302.8 EKE41584.1 - 0.047 12.3 147.3 0.073 11.7 9.4 6.4 2 1 3 6 6 6 0 Giardia variant-specific surface protein Kinase-like PF14531.1 EKE41584.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EKE41584.1 - 0.74 9.4 0.1 1.1 8.9 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.7 EKE41585.1 - 1.7 8.1 19.9 1.9 8.0 12.7 1.8 1 1 1 2 2 2 0 SUR7/PalI family ABM PF03992.11 EKE41586.1 - 1.2e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3962 PF13111.1 EKE41586.1 - 0.022 14.1 0.1 0.027 13.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3962) HnRNP_M PF11532.3 EKE41586.1 - 0.099 12.7 0.3 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Cu-oxidase_2 PF07731.9 EKE41586.1 - 0.22 11.0 2.1 0.29 10.6 0.3 1.9 1 1 1 2 2 2 0 Multicopper oxidase EndoU_bacteria PF14436.1 EKE41589.1 - 0.41 10.4 3.5 0.14 11.9 0.6 1.6 2 0 0 2 2 2 0 Bacterial EndoU nuclease DUF2363 PF10155.4 EKE41589.1 - 5.1 7.0 9.1 0.43 10.5 0.5 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2363) PI3_PI4_kinase PF00454.22 EKE41590.1 - 3.1e-41 141.3 2.3 7.2e-41 140.1 0.4 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EKE41590.1 - 4.5e-10 38.7 0.4 9.8e-10 37.7 0.2 1.6 1 0 0 1 1 1 1 FATC domain DUF3933 PF13069.1 EKE41591.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) RhoGAP PF00620.22 EKE41592.1 - 3e-29 101.6 2.5 3.7e-28 98.0 0.1 2.9 3 0 0 3 3 3 1 RhoGAP domain Ilm1 PF10311.4 EKE41592.1 - 0.0072 15.8 0.0 0.045 13.2 0.0 2.1 2 1 0 2 2 2 1 Increased loss of mitochondrial DNA protein 1 Cob_adeno_trans PF01923.13 EKE41593.1 - 0.024 14.4 0.2 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3573 PF12097.3 EKE41593.1 - 0.038 12.6 3.7 0.037 12.6 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TPD52 PF04201.10 EKE41594.1 - 0.028 14.1 1.6 0.071 12.8 1.1 1.6 1 0 0 1 1 1 0 Tumour protein D52 family Fib_alpha PF08702.5 EKE41594.1 - 0.91 9.6 3.5 1.9 8.5 2.2 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nitroreductase PF00881.19 EKE41595.1 - 2.4e-30 105.5 0.0 3e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Peptidase_S74 PF13884.1 EKE41595.1 - 0.0092 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Baculo_LEF5 PF04838.7 EKE41595.1 - 0.081 12.6 0.3 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 DOCK-C2 PF14429.1 EKE41596.1 - 9.4e-48 162.2 3.0 9.4e-48 162.2 2.1 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EKE41596.1 - 1.9e-15 56.6 2.1 3.3e-15 55.8 0.1 2.5 2 0 0 2 2 2 1 Dedicator of cytokinesis PLAC9 PF15205.1 EKE41596.1 - 0.16 12.2 0.0 0.82 9.9 0.0 2.2 2 0 0 2 2 2 0 Placenta-specific protein 9 LepA_C PF06421.7 EKE41597.1 - 0.0089 15.9 2.7 0.01 15.7 1.9 1.2 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus NOB1_Zn_bind PF08772.6 EKE41599.1 - 3.2e-18 65.2 0.5 3.2e-18 65.2 0.4 2.3 3 0 0 3 3 3 1 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L37e PF01907.14 EKE41599.1 - 0.021 14.6 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e DZR PF12773.2 EKE41599.1 - 0.093 12.5 0.2 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon Oxysterol_BP PF01237.13 EKE41600.1 - 8.3e-79 264.6 1.8 8.3e-79 264.6 1.2 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Actin PF00022.14 EKE41601.1 - 4.5e-45 153.7 0.0 7.4e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Actin Ist1 PF03398.9 EKE41601.1 - 4.8e-30 104.1 0.5 7.4e-30 103.5 0.4 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Filamin PF00630.14 EKE41601.1 - 2.6e-25 88.9 3.5 3e-14 53.4 0.2 2.9 2 1 0 2 2 2 2 Filamin/ABP280 repeat MreB_Mbl PF06723.8 EKE41601.1 - 0.015 13.9 3.3 0.042 12.4 2.3 1.7 1 1 0 1 1 1 0 MreB/Mbl protein DUF4304 PF14137.1 EKE41601.1 - 0.033 14.3 0.6 0.081 13.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) Asp_protease PF09668.5 EKE41601.1 - 0.066 12.7 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-CCCH PF00642.19 EKE41602.1 - 6.1e-27 92.7 13.1 1.1e-13 50.5 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EKE41602.1 - 2e-06 27.5 6.2 0.02 14.8 0.8 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type PMR5N PF14416.1 EKE41602.1 - 0.56 10.3 3.6 3.1 7.9 0.5 2.7 1 1 1 2 2 2 0 PMR5 N terminal Domain LRV_FeS PF05484.6 EKE41602.1 - 1.8 8.1 5.1 3.8 7.1 0.2 2.4 1 1 1 2 2 2 0 LRV protein FeS4 cluster zf-CCHH PF10283.4 EKE41602.1 - 7.7 6.4 10.3 7.3 6.5 0.6 2.9 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif MIF4G PF02854.14 EKE41603.1 - 2.9e-20 72.5 6.5 8.7e-20 71.0 4.5 1.8 1 0 0 1 1 1 1 MIF4G domain Bravo_FIGEY PF13882.1 EKE41603.1 - 0.11 13.3 0.2 0.38 11.6 0.1 1.8 1 0 0 1 1 1 0 Bravo-like intracellular region Pkinase_Tyr PF07714.12 EKE41604.1 - 5.7e-14 51.8 0.0 9.4e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41604.1 - 3.1e-09 36.3 0.0 5.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sec23_trunk PF04811.10 EKE41607.1 - 2.7e-48 164.4 0.0 4.4e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EKE41607.1 - 7.8e-32 108.7 0.2 1.8e-31 107.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EKE41607.1 - 1.4e-18 67.1 0.4 4.4e-18 65.5 0.3 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EKE41607.1 - 1.5e-13 50.0 9.3 3.5e-13 48.8 6.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EKE41607.1 - 1.2e-06 28.0 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Metal_resist PF13801.1 EKE41607.1 - 0.1 12.6 0.0 3.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance VWA PF00092.23 EKE41607.1 - 0.16 11.6 0.0 0.46 10.1 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain Nup54 PF13874.1 EKE41608.1 - 0.0023 17.6 2.8 0.0047 16.5 1.9 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 RPW8 PF05659.6 EKE41608.1 - 0.02 14.4 9.1 0.28 10.6 0.5 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4477 PF14780.1 EKE41608.1 - 0.032 13.5 2.4 0.059 12.7 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) DUF1699 PF08004.6 EKE41608.1 - 0.045 13.2 3.3 0.11 12.0 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1699) DUF4372 PF14294.1 EKE41608.1 - 0.097 12.5 0.1 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) Tmemb_18A PF09771.4 EKE41608.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 Pik1 PF11522.3 EKE41608.1 - 0.12 12.0 1.2 0.41 10.4 0.8 1.9 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 V_ATPase_I PF01496.14 EKE41608.1 - 0.32 8.8 11.9 0.4 8.4 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 EKE41608.1 - 0.41 10.7 5.0 1 9.5 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 EKE41608.1 - 1.6 8.2 16.5 19 4.7 11.5 2.2 1 1 0 1 1 1 0 IncA protein DUF3847 PF12958.2 EKE41608.1 - 4.2 7.1 13.6 0.68 9.7 4.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) TPR_11 PF13414.1 EKE41609.1 - 9e-34 114.9 7.0 8.2e-09 34.9 0.1 5.5 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 EKE41609.1 - 2.3e-27 93.4 7.8 6.9e-05 22.2 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EKE41609.1 - 4.4e-26 88.6 7.5 0.0089 15.8 0.0 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41609.1 - 3.4e-21 75.3 0.0 6.6e-05 23.4 0.6 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EKE41609.1 - 2.3e-15 56.2 8.7 0.0014 18.4 0.0 5.7 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41609.1 - 8.6e-13 47.0 6.5 0.11 12.3 0.1 7.6 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EKE41609.1 - 2.4e-09 36.2 0.6 0.62 9.9 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKE41609.1 - 3.4e-09 36.5 0.6 0.56 10.9 0.0 7.1 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41609.1 - 1e-08 34.6 5.5 1.4 9.2 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKE41609.1 - 3.2e-08 33.3 0.0 3.6 7.5 0.0 5.7 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 EKE41609.1 - 7.6e-08 32.3 9.8 0.039 14.4 0.0 6.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKE41609.1 - 1.4e-05 25.3 3.8 0.11 12.8 0.1 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat Sec1 PF00995.18 EKE41610.1 - 6.2e-107 358.5 8.5 9e-107 358.0 5.9 1.2 1 0 0 1 1 1 1 Sec1 family Metallophos PF00149.23 EKE41611.1 - 3.7e-27 95.0 0.1 6.6e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ras PF00071.17 EKE41612.1 - 1.8e-16 59.9 0.0 2.3e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41612.1 - 1.3e-11 45.0 0.0 2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EKE41612.1 - 0.047 13.3 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Myotub-related PF06602.9 EKE41613.1 - 5.6e-89 298.3 0.0 8.5e-89 297.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 EKE41613.1 - 0.034 13.7 0.1 0.09 12.3 0.1 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EKE41613.1 - 0.04 14.1 0.1 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family RNase_Zc3h12a PF11977.3 EKE41614.1 - 2.6e-19 69.5 0.2 4.5e-19 68.8 0.2 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Claudin_2 PF13903.1 EKE41615.1 - 0.16 11.6 19.3 0.042 13.5 10.0 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CheR PF01739.13 EKE41616.1 - 0.03 13.6 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Rap_GAP PF02145.10 EKE41617.1 - 3.8e-46 156.8 1.4 4.7e-46 156.5 0.1 1.9 2 0 0 2 2 2 1 Rap/ran-GAP C2 PF00168.25 EKE41617.1 - 1.1e-27 95.6 2.5 2.5e-17 62.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EKE41618.1 - 0.01 15.9 0.1 0.013 15.6 0.1 1.4 1 1 0 1 1 1 0 EF-hand domain pair Peptidase_C97 PF05903.9 EKE41621.1 - 3e-26 92.0 0.2 5.2e-26 91.2 0.1 1.4 1 1 0 1 1 1 1 PPPDE putative peptidase domain DUF1462 PF07315.6 EKE41622.1 - 4.6 7.2 7.3 0.7 9.8 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1462) LRR_6 PF13516.1 EKE41623.1 - 4.6 7.6 9.3 11 6.3 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich repeat RWD PF05773.17 EKE41624.1 - 0.0012 18.6 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 RWD domain PNK3P PF08645.6 EKE41625.1 - 0.03 13.7 3.9 0.092 12.1 0.3 2.9 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase PHD_2 PF13831.1 EKE41625.1 - 0.045 13.0 9.6 0.17 11.2 6.6 2.1 1 0 0 1 1 1 0 PHD-finger Suf PF05843.9 EKE41625.1 - 0.48 10.0 5.6 0.31 10.7 1.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-MIZ PF02891.15 EKE41625.1 - 5 6.7 19.2 0.61 9.6 9.0 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Bromodomain PF00439.20 EKE41627.1 - 2.8e-20 72.0 2.6 8.5e-20 70.4 0.1 2.7 2 1 1 3 3 3 1 Bromodomain WD40 PF00400.27 EKE41629.1 - 4.8e-07 29.4 0.5 0.053 13.4 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE41629.1 - 0.0069 16.1 0.0 1 9.1 0.0 2.9 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Peptidase_C25_C PF03785.9 EKE41629.1 - 0.027 14.2 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Exo_endo_phos PF03372.18 EKE41635.1 - 1.1e-18 68.0 0.0 1.7e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EKE41635.1 - 0.039 13.5 1.2 0.081 12.5 0.2 2.1 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF3244 PF11589.3 EKE41635.1 - 1.4 8.6 6.8 5.7 6.6 1.6 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3244) RGS PF00615.14 EKE41636.1 - 9.2e-15 54.7 1.8 9.2e-15 54.7 1.2 3.6 3 1 0 3 3 3 2 Regulator of G protein signaling domain Arm PF00514.18 EKE41638.1 - 0.00013 21.6 1.6 1.1 9.2 0.1 4.7 4 1 0 4 4 4 2 Armadillo/beta-catenin-like repeat TAF8_C PF10406.4 EKE41638.1 - 1.5 8.8 3.9 4.5 7.4 2.7 1.8 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Pkinase_Tyr PF07714.12 EKE41639.1 - 5.6e-57 192.7 0.0 8.9e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41639.1 - 5.5e-51 173.1 0.0 9.8e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EKE41639.1 - 0.03 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKE41639.1 - 0.032 13.5 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 EKE41639.1 - 0.049 13.3 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NGP1NT PF08153.7 EKE41640.1 - 5.4e-37 126.6 4.5 5.4e-37 126.6 3.1 2.1 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EKE41640.1 - 9.3e-18 64.2 0.1 1.2e-13 51.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE41640.1 - 1.5e-05 24.2 0.0 0.00028 20.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EKE41640.1 - 0.00017 21.0 0.8 0.031 13.7 0.0 3.7 3 2 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EKE41640.1 - 0.0023 17.1 0.0 0.0058 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EKE41640.1 - 0.004 16.6 0.0 0.22 10.9 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 EKE41640.1 - 0.0085 15.3 0.1 1.3 8.2 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EKE41640.1 - 0.27 11.0 0.1 0.27 11.0 0.0 4.8 3 2 1 4 4 4 0 Dynamin family zf-ribbon_3 PF13248.1 EKE41641.1 - 5.4e-05 22.2 9.2 0.0001 21.3 6.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EKE41641.1 - 0.00078 19.2 4.3 0.0016 18.2 3.0 1.5 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 EKE41641.1 - 0.00095 18.8 6.5 0.002 17.7 4.5 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Cript PF10235.4 EKE41641.1 - 0.0012 19.1 0.6 0.0036 17.6 0.4 1.9 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zinc_ribbon_2 PF13240.1 EKE41641.1 - 0.0031 16.9 9.9 0.0076 15.6 6.9 1.8 1 0 0 1 1 1 1 zinc-ribbon domain zf-DHHC PF01529.15 EKE41641.1 - 0.033 13.5 2.6 0.034 13.5 1.8 1.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase RRN7 PF11781.3 EKE41641.1 - 0.23 10.9 2.5 7.3 6.1 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-NADH-PPase PF09297.6 EKE41641.1 - 0.98 8.9 7.3 1 8.9 1.4 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-CCHC_3 PF13917.1 EKE41642.1 - 1.5e-08 34.2 1.2 4.2e-08 32.7 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle FtsL PF04999.8 EKE41642.1 - 0.078 12.6 1.9 0.21 11.3 1.3 1.8 1 1 0 1 1 1 0 Cell division protein FtsL zf-CCHC PF00098.18 EKE41642.1 - 0.11 12.5 1.9 0.17 11.8 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle OrfB_Zn_ribbon PF07282.6 EKE41642.1 - 3.2 7.4 7.2 0.24 11.0 1.0 2.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain A_deaminase PF00962.17 EKE41644.1 - 5.7e-35 120.8 0.1 6.8e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.15 EKE41644.1 - 0.013 15.1 0.1 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 Amidohydrolase family Pmp3 PF01679.12 EKE41645.1 - 3.4e-13 49.0 5.5 3.4e-13 49.0 3.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Fe_hyd_lg_C PF02906.9 EKE41647.1 - 1.2e-49 169.1 1.9 1.1e-48 165.9 1.3 2.0 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4 PF00037.22 EKE41647.1 - 7.2e-14 50.7 13.8 9.9e-09 34.4 1.7 5.6 7 0 0 7 7 6 2 4Fe-4S binding domain Fer4_6 PF12837.2 EKE41647.1 - 5.6e-11 41.8 13.0 8.8e-07 28.5 2.0 5.9 6 0 0 6 6 6 3 4Fe-4S binding domain Fer4_11 PF13247.1 EKE41647.1 - 5.1e-09 35.9 17.4 0.00015 21.6 5.5 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EKE41647.1 - 5.5e-09 36.2 38.0 3.3e-05 24.1 10.0 3.6 4 0 0 4 4 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE41647.1 - 9.1e-09 34.9 30.8 8.2e-05 22.3 1.8 5.0 3 1 4 7 7 6 4 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE41647.1 - 3.6e-07 29.7 11.1 8.1e-05 22.3 1.7 6.2 5 1 1 6 6 6 2 4Fe-4S binding domain Fer4_9 PF13187.1 EKE41647.1 - 1.5e-06 28.3 32.0 6.1e-05 23.2 10.9 3.5 4 0 0 4 4 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EKE41647.1 - 5e-05 23.9 26.3 0.00011 22.8 11.8 4.6 3 1 2 5 5 5 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EKE41647.1 - 0.00049 19.8 18.2 0.00049 19.8 12.6 4.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKE41647.1 - 0.0009 19.2 32.1 0.002 18.1 1.7 4.7 2 1 3 5 5 4 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 EKE41647.1 - 0.00096 19.2 14.0 0.0039 17.4 2.5 6.1 8 0 0 8 8 4 2 4Fe-4S binding domain Fer4_3 PF12798.2 EKE41647.1 - 0.01 16.3 5.8 0.01 16.3 4.0 6.0 7 0 0 7 7 5 0 4Fe-4S binding domain Fer4_18 PF13746.1 EKE41647.1 - 0.015 15.6 1.4 0.015 15.6 1.0 5.0 5 1 1 6 6 6 0 4Fe-4S dicluster domain Fer4_13 PF13370.1 EKE41647.1 - 0.058 13.8 0.7 0.058 13.8 0.5 3.8 4 1 0 4 4 2 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 EKE41647.1 - 4.5 7.9 20.1 2.1 8.9 0.8 4.1 2 1 1 3 3 3 0 4Fe-4S single cluster domain Acetyltransf_1 PF00583.19 EKE41648.1 - 9.4e-18 64.0 0.0 1.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKE41648.1 - 1.7e-09 37.8 0.0 2.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKE41648.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKE41648.1 - 2.2e-06 27.8 0.0 5.3e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKE41648.1 - 2.8e-06 27.3 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE41648.1 - 1.3e-05 25.0 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKE41648.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EKE41648.1 - 0.00094 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.1 EKE41648.1 - 0.0039 17.1 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 EKE41648.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain CLU_N PF15044.1 EKE41651.1 - 0.026 14.6 2.7 0.12 12.4 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial function, CLU-N-term TLD PF07534.11 EKE41651.1 - 0.034 14.1 0.4 0.075 13.0 0.2 1.6 1 0 0 1 1 1 0 TLD DHC_N2 PF08393.8 EKE41651.1 - 0.038 12.4 0.2 0.055 11.9 0.2 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 RhoGAP PF00620.22 EKE41652.1 - 2.9e-38 130.8 1.0 5e-38 130.0 0.7 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EKE41652.1 - 0.00063 18.6 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) IBN_N PF03810.14 EKE41653.1 - 9.4e-09 35.0 2.3 1.8e-08 34.2 0.4 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 EKE41653.1 - 2.5e-06 27.0 0.0 0.27 11.4 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.15 EKE41653.1 - 0.00048 18.5 2.9 0.0029 16.0 0.0 2.6 3 0 0 3 3 3 1 Adaptin N terminal region UPF0147 PF03685.8 EKE41653.1 - 0.049 13.5 0.0 0.19 11.6 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) HEAT_2 PF13646.1 EKE41653.1 - 0.058 13.6 0.0 5 7.4 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats RhoGEF PF00621.15 EKE41656.1 - 1.1e-16 61.2 6.3 1.1e-16 61.2 4.4 4.4 7 0 0 7 7 7 1 RhoGEF domain ArfGap PF01412.13 EKE41656.1 - 1.8e-12 47.0 0.7 1.2e-11 44.4 0.5 2.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EKE41656.1 - 8.8e-10 38.7 2.5 1e-07 32.0 0.1 4.0 3 1 0 3 3 3 2 PH domain CH PF00307.26 EKE41656.1 - 8.7e-05 22.5 0.1 8.7e-05 22.5 0.1 3.8 5 0 0 5 5 5 1 Calponin homology (CH) domain IQ PF00612.22 EKE41656.1 - 0.0014 18.0 0.0 0.091 12.4 0.0 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif F-box PF00646.28 EKE41657.1 - 1e-07 31.3 0.3 6.2e-07 28.9 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EKE41657.1 - 4.3e-06 26.3 0.1 1.6e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EKE41657.1 - 0.0081 15.8 10.2 0.016 14.9 2.5 6.3 2 2 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 EKE41657.1 - 3.2 8.1 28.1 17 5.9 0.0 8.8 7 3 3 10 10 10 0 Leucine Rich Repeat PP2C PF00481.16 EKE41658.1 - 7.8e-33 113.9 0.0 7.8e-33 113.9 0.0 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE41658.1 - 2e-07 30.9 0.0 0.00075 19.2 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EKE41658.1 - 3.3e-05 23.3 0.0 0.0002 20.8 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C zf-SNAP50_C PF12251.3 EKE41659.1 - 4.6e-31 107.7 3.7 8.4e-31 106.8 2.6 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Thy1 PF02511.10 EKE41659.1 - 0.062 12.6 0.4 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Thymidylate synthase complementing protein Lectin_leg-like PF03388.8 EKE41661.1 - 4.1e-31 107.8 0.4 6.1e-31 107.3 0.3 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EKE41661.1 - 5.9e-06 25.8 1.0 0.0023 17.3 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain NDK PF00334.14 EKE41662.1 - 7.9e-28 96.9 0.0 1.5e-27 96.0 0.0 1.5 1 1 0 1 1 1 1 Nucleoside diphosphate kinase DUF4473 PF14747.1 EKE41662.1 - 0.2 11.9 4.5 3 8.1 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) Dehydratase_hem PF13816.1 EKE41663.1 - 0.2 10.6 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Haem-containing dehydratase ArfGap PF01412.13 EKE41664.1 - 3.2e-41 139.7 2.6 3.2e-41 139.7 1.8 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF3492 PF11997.3 EKE41664.1 - 1.4 8.3 5.4 0.69 9.4 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3492) CENP-F_leu_zip PF10473.4 EKE41665.1 - 0.0077 16.0 26.2 0.0077 16.0 18.2 7.2 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EKE41665.1 - 0.062 12.4 17.4 0.57 9.3 0.2 3.7 2 1 0 3 3 3 0 Reovirus sigma C capsid protein VMA21 PF09446.5 EKE41666.1 - 0.055 13.3 0.5 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 VMA21-like domain RraB PF06877.6 EKE41666.1 - 0.22 12.1 2.2 0.48 11.0 1.5 1.6 1 1 0 1 1 1 0 Regulator of ribonuclease activity B Ribosomal_S10 PF00338.17 EKE41667.1 - 4.2e-28 97.0 0.5 5e-28 96.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NT-C2 PF10358.4 EKE41668.1 - 2.9e-23 81.9 5.0 8.3e-23 80.4 3.4 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EKE41668.1 - 1.2e-06 28.3 1.3 2.7e-06 27.1 0.9 1.7 1 0 0 1 1 1 1 DIL domain Flavi_glycop_C PF02832.11 EKE41668.1 - 2.3 8.1 8.4 0.77 9.6 0.1 3.8 2 2 2 4 4 4 0 Flavivirus glycoprotein, immunoglobulin-like domain Ras PF00071.17 EKE41669.1 - 2.1e-53 180.0 0.0 2.5e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41669.1 - 2.3e-15 57.1 0.0 3.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41669.1 - 2.2e-08 33.5 0.0 2.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNHCP PF12647.2 EKE41669.1 - 0.02 14.7 0.2 0.031 14.1 0.2 1.3 1 0 0 1 1 1 0 RNHCP domain MMR_HSR1 PF01926.18 EKE41669.1 - 0.06 13.3 0.0 0.082 12.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Phage_antitermQ PF06530.7 EKE41670.1 - 0.2 11.1 1.8 1.1 8.8 0.2 2.8 2 2 2 4 4 4 0 Phage antitermination protein Q Peptidase_C1 PF00112.18 EKE41672.1 - 1.9e-30 106.3 1.3 3.7e-30 105.4 0.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE41672.1 - 2.2e-11 43.8 5.0 4e-11 42.9 3.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) GP41 PF00517.12 EKE41672.1 - 0.2 11.1 2.1 3.9 6.9 1.2 2.2 2 0 0 2 2 2 0 Retroviral envelope protein Kinesin PF00225.18 EKE41673.1 - 3.3e-92 308.7 2.9 3.3e-92 308.7 2.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Bac_DnaA PF00308.13 EKE41673.1 - 0.0037 16.9 4.3 0.14 11.8 1.9 3.0 2 0 0 2 2 2 1 Bacterial dnaA protein Reo_sigmaC PF04582.7 EKE41673.1 - 0.013 14.7 0.9 0.013 14.7 0.6 2.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Herpes_BLRF2 PF05812.7 EKE41673.1 - 0.064 13.0 0.0 0.064 13.0 0.0 4.0 3 1 1 4 4 4 0 Herpesvirus BLRF2 protein Thioredoxin_8 PF13905.1 EKE41673.1 - 0.076 13.1 2.5 1.6 8.8 0.1 3.3 2 0 0 2 2 2 0 Thioredoxin-like V_ATPase_I PF01496.14 EKE41673.1 - 4.4 5.0 25.4 7.9 4.2 17.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC92 PF14916.1 EKE41673.1 - 9.3 5.9 14.6 0.74 9.4 0.1 4.1 4 0 0 4 4 4 0 Coiled-coil domain of unknown function dUTPase PF00692.14 EKE41674.1 - 1e-10 41.1 0.0 3.5e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 dUTPase DCD PF06559.6 EKE41674.1 - 0.14 10.5 0.0 0.28 9.5 0.0 1.6 1 1 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) RraB PF06877.6 EKE41675.1 - 0.11 13.1 0.0 1.4 9.6 0.0 2.4 2 0 0 2 2 2 0 Regulator of ribonuclease activity B DUF399 PF04187.8 EKE41675.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Copine PF07002.11 EKE41676.1 - 3.4e-44 150.1 0.1 4.6e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EKE41676.1 - 2.6e-13 50.2 0.0 4.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EKE41676.1 - 5.8e-06 26.5 0.0 7.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE41676.1 - 0.00024 20.8 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain CCDC-167 PF15188.1 EKE41677.1 - 0.054 13.4 0.3 0.086 12.7 0.1 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DnaJ PF00226.26 EKE41678.1 - 1.9e-12 46.7 0.2 6e-12 45.1 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Gin PF10764.4 EKE41678.1 - 0.13 12.0 1.9 0.13 12.0 0.3 1.8 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin DIT1_PvcA PF05141.7 EKE41678.1 - 0.2 10.9 11.5 0.03 13.6 3.5 2.0 1 1 1 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein COX16 PF14138.1 EKE41678.1 - 0.22 11.7 15.5 1.3 9.1 10.7 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Fumble PF03630.9 EKE41679.1 - 1.1e-90 303.9 0.0 1.4e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Fumble Pkinase PF00069.20 EKE41680.1 - 5.3e-63 212.5 0.0 8.6e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41680.1 - 4.3e-36 124.3 0.0 8e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.18 EKE41680.1 - 1.1e-07 31.8 0.0 6.4e-07 29.3 0.0 2.4 2 0 0 2 2 1 1 50S ribosome-binding GTPase Septin PF00735.13 EKE41680.1 - 4.6e-07 29.1 0.8 0.00054 19.0 0.2 2.4 1 1 1 2 2 2 2 Septin AAA_22 PF13401.1 EKE41680.1 - 1.2e-05 25.4 0.0 7.6e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKE41680.1 - 8.8e-05 22.0 0.5 0.017 14.5 0.0 2.9 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EKE41680.1 - 0.00051 20.5 0.2 0.0083 16.6 0.0 3.0 2 1 1 3 3 2 1 Miro-like protein EF-hand_7 PF13499.1 EKE41680.1 - 0.0025 17.9 0.4 0.013 15.6 0.3 2.2 1 1 0 1 1 1 1 EF-hand domain pair Gtr1_RagA PF04670.7 EKE41680.1 - 0.0033 16.6 0.1 0.0098 15.0 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EKE41680.1 - 0.0043 17.0 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EKE41680.1 - 0.0052 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 EKE41680.1 - 0.0083 15.5 0.4 0.065 12.6 0.3 2.3 1 1 0 1 1 1 1 Ras family KaiC PF06745.8 EKE41680.1 - 0.0097 15.0 0.5 0.087 11.9 0.0 2.6 2 0 0 2 2 2 1 KaiC Kinase-like PF14531.1 EKE41680.1 - 0.01 14.8 0.0 0.023 13.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like cobW PF02492.14 EKE41680.1 - 0.015 14.7 2.0 0.064 12.6 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EKE41680.1 - 0.016 16.0 0.0 0.072 13.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKE41680.1 - 0.017 15.4 0.1 0.1 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EKE41680.1 - 0.034 13.6 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 EKE41680.1 - 0.038 13.7 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) EF-hand_6 PF13405.1 EKE41680.1 - 0.041 13.7 2.1 0.14 12.0 0.6 2.5 2 0 0 2 2 2 0 EF-hand domain AAA PF00004.24 EKE41680.1 - 0.076 13.2 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EKE41680.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKE41680.1 - 0.083 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.22 EKE41680.1 - 0.092 12.1 0.1 0.092 12.1 0.1 2.3 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 EKE41680.1 - 0.096 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain A2L_zn_ribbon PF08792.5 EKE41680.1 - 3.1 7.3 12.6 1 8.9 5.7 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain Ras PF00071.17 EKE41681.1 - 8.6e-46 155.2 0.1 1.1e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41681.1 - 5.4e-20 72.0 0.0 9.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41681.1 - 4.9e-16 58.4 0.1 8.7e-16 57.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKE41681.1 - 4.9e-07 29.1 0.1 1.6e-06 27.4 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKE41681.1 - 9.7e-06 25.1 0.4 6.3e-05 22.5 0.3 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EKE41681.1 - 1.1e-05 24.6 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.24 EKE41681.1 - 2.5e-05 24.5 0.0 3.9e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EKE41681.1 - 6.5e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE41681.1 - 0.00028 20.3 0.2 0.0069 15.8 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EKE41681.1 - 0.0017 17.5 0.2 0.004 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKE41681.1 - 0.0017 18.4 0.1 0.004 17.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EKE41681.1 - 0.0046 16.2 0.0 1.4 8.1 0.1 2.2 1 1 1 2 2 2 2 Ferrous iron transport protein B AAA_5 PF07728.9 EKE41681.1 - 0.0048 16.6 0.2 0.0094 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKE41681.1 - 0.013 15.5 0.2 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EKE41681.1 - 0.016 14.8 0.2 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain MCM PF00493.18 EKE41681.1 - 0.022 13.5 0.1 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_18 PF13238.1 EKE41681.1 - 0.028 14.7 0.1 0.053 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EKE41681.1 - 0.069 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EKE41681.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EKE41681.1 - 0.09 12.3 0.1 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EKE41681.1 - 0.13 11.7 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EKE41681.1 - 0.4 9.3 3.9 2.8 6.5 0.1 2.4 1 1 1 3 3 3 0 G-protein alpha subunit SMC_N PF02463.14 EKE41682.1 - 3.5e-51 173.5 74.3 1.1e-31 109.7 0.0 4.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKE41682.1 - 9.9e-21 73.9 0.0 4.8e-20 71.7 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EKE41682.1 - 8.9e-10 38.9 18.7 1.3e-05 25.3 0.0 5.6 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EKE41682.1 - 0.00027 20.4 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.7 EKE41682.1 - 0.0071 16.0 13.0 0.0071 16.0 9.0 9.5 3 3 6 9 9 9 4 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EKE41682.1 - 4.9 6.2 15.8 11 5.0 0.3 5.1 2 2 3 5 5 5 0 Reovirus sigma C capsid protein Mic1 PF07035.7 EKE41683.1 - 4e-15 55.5 2.4 6.4e-15 54.9 1.7 1.3 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Vps39_1 PF10366.4 EKE41683.1 - 0.084 12.8 1.3 0.37 10.8 0.3 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 Herpes_gI PF01688.12 EKE41684.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I SDH_beta PF03315.10 EKE41685.1 - 0.86 9.6 5.3 0.1 12.6 0.3 1.8 1 1 1 2 2 2 0 Serine dehydratase beta chain TIM PF00121.13 EKE41686.1 - 2.4e-91 305.1 6.1 2.8e-91 304.9 4.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3168 PF11367.3 EKE41686.1 - 0.082 13.0 0.1 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3168) Fcf1 PF04900.7 EKE41686.1 - 0.13 12.3 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Fcf1 AdoHcyase PF05221.12 EKE41687.1 - 0.028 13.3 0.7 0.06 12.2 0.5 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Ribosomal_S4Pg PF11993.3 EKE41687.1 - 0.065 13.0 4.3 0.027 14.2 1.3 1.6 2 0 0 2 2 2 0 Ribosomal S4P (gammaproteobacterial) SPOB_a PF14689.1 EKE41687.1 - 0.094 12.2 3.2 1.8 8.1 0.1 3.5 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Methyltransf_12 PF08242.7 EKE41687.1 - 0.28 11.6 2.1 4.9 7.6 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain Casein PF00363.13 EKE41687.1 - 0.69 10.5 3.1 24 5.6 1.5 2.7 1 1 1 2 2 2 0 Casein DUF3510 PF12022.3 EKE41687.1 - 0.84 9.7 12.5 0.13 12.3 1.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) QLQ PF08880.6 EKE41688.1 - 0.097 12.0 1.9 0.27 10.6 1.3 1.8 1 0 0 1 1 1 0 QLQ Reo_sigmaC PF04582.7 EKE41689.1 - 6.2 5.9 8.0 1.3 8.1 0.8 2.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein AAA PF00004.24 EKE41690.1 - 1.4e-07 31.7 0.0 4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EKE41690.1 - 1.8e-05 24.5 0.1 6.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain zf-RING_3 PF14369.1 EKE41691.1 - 0.026 14.5 0.5 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 zinc-finger SLBP_RNA_bind PF15247.1 EKE41692.1 - 3.1e-27 94.1 2.7 3.1e-27 94.1 1.9 1.7 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain DUF1917 PF08939.5 EKE41692.1 - 0.057 13.1 0.5 0.076 12.7 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) ICMT PF04140.9 EKE41693.1 - 9.2e-27 93.0 2.8 2.1e-26 91.9 2.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EKE41693.1 - 3.6e-10 39.8 3.9 3.6e-10 39.8 2.7 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EKE41693.1 - 0.00029 20.1 3.2 0.00039 19.7 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 EKE41693.1 - 0.096 12.0 3.9 0.018 14.4 0.5 1.5 2 0 0 2 2 2 0 NnrU protein SHOCT PF09851.4 EKE41694.1 - 0.078 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Short C-terminal domain Sec63 PF02889.11 EKE41695.1 - 1.7e-88 296.9 0.6 4.1e-88 295.6 0.0 2.0 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.24 EKE41695.1 - 8.5e-34 116.4 18.6 1.6e-25 89.5 0.1 4.7 5 1 0 5 5 5 2 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE41695.1 - 8.3e-10 38.9 0.7 0.00066 19.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain Helicase_C PF00271.26 EKE41695.1 - 1.8e-09 37.3 0.0 6.7e-09 35.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EKE41695.1 - 7.2e-06 25.3 6.7 0.00088 18.5 0.1 3.4 3 1 0 3 3 3 2 PhoH-like protein AAA_16 PF13191.1 EKE41695.1 - 0.0012 18.8 0.0 0.15 12.0 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EKE41695.1 - 0.012 15.3 0.0 0.45 10.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 EKE41695.1 - 0.052 12.9 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF872 PF05915.7 EKE41696.1 - 0.017 14.9 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) LON PF02190.11 EKE41696.1 - 0.022 14.4 0.9 0.026 14.1 0.6 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF2207 PF09972.4 EKE41696.1 - 0.023 13.3 0.1 0.026 13.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TM_helix PF05552.7 EKE41696.1 - 0.057 13.0 0.7 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Conserved TM helix PglZ PF08665.7 EKE41696.1 - 0.059 13.0 0.2 0.078 12.6 0.2 1.2 1 0 0 1 1 1 0 PglZ domain DUF3693 PF12472.3 EKE41696.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Phage related protein E1-E2_ATPase PF00122.15 EKE41696.1 - 0.13 11.2 0.4 0.21 10.5 0.1 1.4 1 1 1 2 2 2 0 E1-E2 ATPase DUF2374 PF09574.5 EKE41696.1 - 0.14 11.8 1.2 0.22 11.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) DUF2975 PF11188.3 EKE41696.1 - 0.21 11.2 3.4 0.3 10.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4064 PF13273.1 EKE41696.1 - 0.3 11.2 3.0 0.66 10.1 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Clat_adaptor_s PF01217.15 EKE41697.1 - 2e-26 92.4 5.3 2.2e-26 92.2 3.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ubiquitin PF00240.18 EKE41698.1 - 0.0001 21.6 0.1 0.00025 20.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family TUG-UBL1 PF11470.3 EKE41698.1 - 0.00021 21.1 0.0 0.00063 19.6 0.0 1.9 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBA PF00627.26 EKE41698.1 - 0.0049 16.6 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EKE41698.1 - 0.039 13.6 0.3 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like RabGAP-TBC PF00566.13 EKE41699.1 - 3.2e-33 114.9 7.5 3.2e-33 114.9 5.2 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MraZ PF02381.13 EKE41700.1 - 0.061 13.0 1.8 4.9 6.9 0.0 2.9 2 1 1 3 3 3 0 MraZ protein FF PF01846.14 EKE41701.1 - 0.0098 15.8 0.9 3.9 7.5 0.0 2.5 2 0 0 2 2 2 2 FF domain DUF778 PF05608.7 EKE41702.1 - 1.7e-18 66.8 6.6 2.3e-10 40.5 0.5 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF778) Phg_2220_C PF09524.5 EKE41702.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) FixP_N PF14715.1 EKE41702.1 - 2.2 7.7 5.0 0.31 10.4 0.4 1.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Thioredoxin PF00085.15 EKE41703.1 - 1.7e-16 59.7 0.2 1.2e-10 41.0 0.1 2.7 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EKE41703.1 - 3.1e-09 37.0 0.2 5.6e-06 26.5 0.1 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKE41703.1 - 0.0001 22.3 0.8 0.00046 20.2 0.3 2.3 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EKE41703.1 - 0.0033 17.4 0.1 0.011 15.7 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EKE41704.1 - 7.2e-60 200.3 0.8 8.1e-60 200.1 0.6 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EKE41704.1 - 0.00061 19.4 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EKE41704.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.1 EKE41704.1 - 0.019 15.0 0.1 0.029 14.4 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF3192 PF11399.3 EKE41704.1 - 0.056 13.3 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Thioredoxin_2 PF13098.1 EKE41704.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_tranf_2_4 PF13704.1 EKE41704.1 - 0.13 12.5 0.2 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ras PF00071.17 EKE41705.1 - 1.1e-15 57.3 0.5 2.1e-15 56.4 0.3 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKE41705.1 - 3.6e-06 27.4 0.6 8.6e-06 26.2 0.1 1.8 2 1 0 2 2 2 1 Miro-like protein Ligase_CoA PF00549.14 EKE41705.1 - 0.0035 16.9 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 CoA-ligase MSC PF09402.5 EKE41705.1 - 0.0074 15.0 0.4 0.0092 14.7 0.3 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain AAA_17 PF13207.1 EKE41705.1 - 0.021 15.6 0.3 0.067 14.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EKE41705.1 - 0.042 13.8 0.3 0.14 12.0 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EKE41705.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKE41705.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain CENP-M PF11111.3 EKE41705.1 - 0.12 11.5 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) DUF258 PF03193.11 EKE41705.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EKE41705.1 - 0.13 11.8 0.6 0.51 9.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 EKE41706.1 - 1.2e-25 88.9 0.1 2e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41706.1 - 4.2e-19 68.2 0.0 3.8e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41706.1 - 4.1e-17 61.7 0.3 1e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C2 PF00648.16 EKE41707.1 - 2.9e-60 203.7 0.0 3.8e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease LIM PF00412.17 EKE41707.1 - 3.2e-07 30.3 3.3 1.1e-06 28.6 2.3 2.0 1 0 0 1 1 1 1 LIM domain DZR PF12773.2 EKE41707.1 - 0.11 12.3 7.6 2.4 8.0 5.2 2.6 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.20 EKE41708.1 - 1.3e-52 178.5 0.0 1.6e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41708.1 - 1.3e-23 83.3 0.0 1.9e-23 82.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41708.1 - 0.0049 15.8 0.0 0.0067 15.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE41708.1 - 0.0097 15.6 0.1 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RhoGAP PF00620.22 EKE41709.1 - 3.3e-25 88.4 0.7 3.3e-25 88.4 0.5 1.9 2 0 0 2 2 2 1 RhoGAP domain tRNA-synt_2c PF01411.14 EKE41710.1 - 7e-06 24.6 5.3 1e-05 24.0 3.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Prenyltrans_2 PF13249.1 EKE41710.1 - 9.6e-06 25.9 0.5 0.0024 18.2 0.1 2.4 1 1 2 3 3 3 3 Prenyltransferase-like DUF2775 PF10950.3 EKE41710.1 - 4.2 7.6 10.0 1.5 9.1 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2775) Arm PF00514.18 EKE41711.1 - 9.2e-09 34.8 2.3 0.00012 21.7 0.3 5.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EKE41711.1 - 0.07 13.4 0.0 0.63 10.3 0.0 2.6 2 1 0 2 2 2 0 HEAT repeats IBB PF01749.15 EKE41711.1 - 0.098 12.8 1.2 0.19 11.9 0.9 1.4 1 0 0 1 1 1 0 Importin beta binding domain DUF1765 PF08578.5 EKE41711.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1765) HEAT_EZ PF13513.1 EKE41711.1 - 0.13 12.7 0.3 0.53 10.8 0.2 2.1 1 0 0 1 1 1 0 HEAT-like repeat MatC_N PF07158.6 EKE41712.1 - 8.1 6.2 13.3 0.21 11.3 3.6 2.2 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus DJ-1_PfpI PF01965.19 EKE41713.1 - 2.8e-31 107.9 0.0 3.4e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EKE41713.1 - 5.8e-16 58.2 0.1 6.7e-16 58.0 0.1 1.0 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EKE41713.1 - 0.044 13.3 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain zf-ribbon_3 PF13248.1 EKE41714.1 - 8.4e-06 24.8 5.3 2.4e-05 23.3 1.8 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EKE41714.1 - 1.4e-05 24.4 1.0 1.4e-05 24.4 0.7 2.4 2 0 0 2 2 2 1 zinc-ribbon domain UPF0547 PF10571.4 EKE41714.1 - 0.0001 21.8 7.0 0.16 11.7 0.5 3.2 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 LIM PF00412.17 EKE41714.1 - 0.00027 20.9 1.2 0.00027 20.9 0.8 2.4 2 1 0 2 2 2 1 LIM domain DZR PF12773.2 EKE41714.1 - 0.001 18.8 6.6 0.0039 16.9 4.6 1.9 1 1 0 1 1 1 1 Double zinc ribbon Cript PF10235.4 EKE41714.1 - 0.0039 17.5 5.7 0.15 12.4 1.5 2.2 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT NOB1_Zn_bind PF08772.6 EKE41714.1 - 0.03 14.1 0.6 0.03 14.1 0.4 1.9 3 0 0 3 3 2 0 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.11 EKE41714.1 - 0.031 13.9 0.6 0.031 13.9 0.4 2.2 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF2175 PF09943.4 EKE41714.1 - 0.045 13.7 2.5 0.058 13.4 1.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) FYVE PF01363.16 EKE41714.1 - 0.12 12.2 4.6 5.4 6.9 3.2 2.5 1 1 0 1 1 1 0 FYVE zinc finger zf-NADH-PPase PF09297.6 EKE41714.1 - 0.17 11.3 8.9 0.89 9.1 0.6 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_L32p PF01783.18 EKE41714.1 - 0.19 11.9 4.2 0.59 10.3 0.5 2.5 1 1 1 2 2 2 0 Ribosomal L32p protein family Zn_Tnp_IS91 PF14319.1 EKE41714.1 - 0.26 10.7 4.5 0.12 11.8 1.1 1.7 2 0 0 2 2 2 0 Transposase zinc-binding domain OrfB_Zn_ribbon PF07282.6 EKE41714.1 - 0.46 10.1 6.9 0.38 10.4 1.9 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain C1_1 PF00130.17 EKE41714.1 - 0.8 9.4 7.2 8.1 6.2 0.8 2.9 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.9 EKE41714.1 - 0.85 9.3 3.8 7.9 6.2 0.1 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid HypA PF01155.14 EKE41714.1 - 0.99 9.1 5.5 1.1 8.9 1.4 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2296 PF10058.4 EKE41714.1 - 1 9.1 3.6 8.5 6.2 0.0 3.0 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-dskA_traR PF01258.12 EKE41714.1 - 1.1 9.1 8.9 35 4.2 0.0 3.2 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Ribosomal_L37e PF01907.14 EKE41714.1 - 1.2 8.9 6.4 3.3 7.5 0.5 2.5 2 1 0 2 2 2 0 Ribosomal protein L37e DUF329 PF03884.9 EKE41714.1 - 1.7 8.2 4.9 4.9 6.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF329) PhnA_Zn_Ribbon PF08274.7 EKE41714.1 - 2.4 7.9 5.0 15 5.4 0.9 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF3039 PF11238.3 EKE41714.1 - 3.5 7.1 6.0 8.3 5.9 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3039) zf-RING_3 PF14369.1 EKE41714.1 - 3.9 7.5 6.4 2.3 8.2 0.2 2.7 2 1 1 3 3 3 0 zinc-finger zf-C2H2 PF00096.21 EKE41714.1 - 4.5 7.8 8.6 33 5.0 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.1 EKE41714.1 - 7.1 6.4 8.8 20 4.9 0.1 3.1 3 0 0 3 3 3 0 Nudix N-terminal Zn-ribbon_8 PF09723.5 EKE41714.1 - 7.4 6.6 8.4 4.5 7.2 0.4 3.1 2 1 0 3 3 3 0 Zinc ribbon domain Hist_deacetyl PF00850.14 EKE41715.1 - 2e-05 24.0 0.0 0.00026 20.4 0.0 2.4 2 1 0 2 2 2 1 Histone deacetylase domain DUF914 PF06027.7 EKE41716.1 - 3.9e-31 108.1 31.5 5.4e-31 107.6 21.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EKE41716.1 - 3.9e-07 29.8 37.3 0.00094 18.8 12.5 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EKE41716.1 - 1.3e-05 25.3 7.8 1.3e-05 25.3 5.4 2.6 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EKE41716.1 - 0.00015 21.7 44.0 0.0038 17.2 9.7 2.7 2 2 1 3 3 3 2 EamA-like transporter family Ras PF00071.17 EKE41717.1 - 6.7e-37 126.3 0.7 8.5e-37 126.0 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41717.1 - 2.6e-21 76.3 0.1 1.6e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE41717.1 - 2.9e-11 42.9 0.2 3.4e-11 42.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE41717.1 - 1.2e-06 27.8 0.2 1.4e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EKE41717.1 - 8.8e-05 21.3 0.2 0.00038 19.2 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 EKE41717.1 - 0.002 18.2 0.1 0.059 13.5 0.0 2.2 1 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKE41717.1 - 0.0069 16.3 0.1 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 EKE41717.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 EKE41717.1 - 0.014 14.8 0.3 0.039 13.4 0.2 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Coatomer_WDAD PF04053.9 EKE41717.1 - 0.021 13.6 0.1 0.028 13.2 0.1 1.2 1 0 0 1 1 1 0 Coatomer WD associated region FeoB_N PF02421.13 EKE41717.1 - 0.042 13.1 0.1 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EKE41717.1 - 0.07 12.6 0.6 5.7 6.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EKE41717.1 - 0.12 11.8 0.4 0.29 10.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain DUF2363 PF10155.4 EKE41718.1 - 3.4e-15 56.0 5.5 5.9e-15 55.3 3.8 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) NdhN PF11909.3 EKE41718.1 - 0.18 11.1 0.7 0.49 9.7 0.1 1.9 2 0 0 2 2 2 0 NADH-quinone oxidoreductase cyanobacterial subunit N Vip3A_N PF12495.3 EKE41718.1 - 3.9 7.1 8.5 4 7.0 0.4 2.4 2 1 0 2 2 2 0 Vegetative insecticide protein 3A N terminal SMK-1 PF04802.10 EKE41719.1 - 1.5e-13 50.7 8.0 2.7e-13 49.8 3.1 2.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RGS PF00615.14 EKE41719.1 - 2.7 8.1 12.0 0.13 12.3 0.6 4.2 4 1 0 4 4 4 0 Regulator of G protein signaling domain LRR_5 PF13306.1 EKE41721.1 - 1.4e-83 277.0 33.4 5.4e-34 116.6 5.2 3.7 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41721.1 - 4.8e-38 128.7 7.8 6.6e-10 38.5 0.2 6.7 1 1 7 8 8 8 8 Leucine rich repeat zf-DHHC PF01529.15 EKE41722.1 - 1.9e-34 118.5 10.1 1.9e-34 118.5 7.0 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Bax1-I PF01027.15 EKE41722.1 - 0.0014 18.3 16.1 0.1 12.1 1.4 2.2 2 0 0 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 Glycophorin_A PF01102.13 EKE41722.1 - 0.18 11.6 2.2 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A Aminotran_5 PF00266.14 EKE41723.1 - 2e-35 122.2 0.0 2.9e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EKE41723.1 - 2.1e-10 40.1 0.2 6.8e-10 38.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II E1-E2_ATPase PF00122.15 EKE41724.1 - 2.2e-58 196.9 8.8 2.2e-58 196.9 6.1 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKE41724.1 - 1.6e-40 138.5 7.8 1.6e-40 138.5 5.4 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKE41724.1 - 1.5e-33 117.0 0.1 7.8e-33 114.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE41724.1 - 6.5e-21 74.0 0.3 1.5e-20 72.8 0.2 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EKE41724.1 - 4.9e-19 67.5 0.0 1.4e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EKE41724.1 - 2.1e-13 50.8 0.0 7.8e-13 49.0 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKE41724.1 - 1.3e-06 28.1 6.2 2.1e-05 24.2 0.2 3.1 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Adaptin_N PF01602.15 EKE41725.1 - 1.1e-58 198.9 35.5 1.2e-58 198.7 23.9 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EKE41725.1 - 1.1e-48 164.2 0.2 3.6e-48 162.5 0.1 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EKE41725.1 - 1.2e-27 96.3 0.1 3.8e-27 94.6 0.1 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EKE41725.1 - 4.4e-09 36.4 1.2 0.0067 16.6 0.0 4.6 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.17 EKE41725.1 - 0.0069 16.3 5.5 1.2 9.3 0.0 4.8 5 1 0 5 5 5 1 HEAT repeat AP4E_app_platf PF14807.1 EKE41725.1 - 0.0091 16.2 0.7 0.065 13.4 0.0 2.8 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform VirDNA-topo-I_N PF09266.5 EKE41725.1 - 0.13 12.1 1.7 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal GED PF02212.13 EKE41725.1 - 0.24 11.3 5.5 9.2 6.2 0.0 3.7 3 0 0 3 3 3 0 Dynamin GTPase effector domain BING4CT PF08149.6 EKE41726.1 - 5.4e-26 89.9 0.0 3.4e-25 87.3 0.0 2.3 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EKE41726.1 - 6.9e-08 32.0 0.0 8.3e-05 22.3 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat CNH PF00780.17 EKE41726.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 CNH domain TLD PF07534.11 EKE41728.1 - 1.9e-07 31.1 0.5 8.2e-07 29.0 0.1 2.1 1 1 0 2 2 2 1 TLD DUF1413 PF07205.6 EKE41728.1 - 0.014 14.9 0.8 0.079 12.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) RRM_1 PF00076.17 EKE41728.1 - 0.02 14.5 0.2 0.048 13.2 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Linocin_M18 PF04454.7 EKE41728.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase DEAD PF00270.24 EKE41729.1 - 3.9e-36 124.0 0.0 1.9e-35 121.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE41729.1 - 8e-26 89.7 0.0 1.8e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE41729.1 - 0.00044 20.1 2.2 0.0011 18.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EKE41729.1 - 0.093 12.8 1.9 2 8.5 0.0 3.2 3 1 0 3 3 3 0 AAA domain OKR_DC_1 PF01276.15 EKE41730.1 - 4e-126 420.9 0.1 5e-81 272.3 0.3 2.3 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.10 EKE41730.1 - 2.3e-25 89.2 0.1 7.2e-25 87.6 0.0 1.9 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.10 EKE41730.1 - 2.4e-10 40.4 0.3 5.4e-07 29.6 0.0 2.9 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, N-terminal domain Beta_elim_lyase PF01212.16 EKE41730.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EKE41730.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NARP1 PF12569.3 EKE41731.1 - 1.6e-45 155.8 15.2 2e-44 152.2 9.9 2.5 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EKE41731.1 - 1.4e-14 53.4 15.1 7.2e-05 22.3 0.1 5.9 6 1 0 6 6 6 3 TPR repeat TPR_16 PF13432.1 EKE41731.1 - 1.6e-14 54.1 1.9 0.0054 17.3 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKE41731.1 - 2.5e-14 51.9 15.6 0.00039 20.1 0.0 7.2 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EKE41731.1 - 9e-11 41.4 2.0 0.21 12.3 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EKE41731.1 - 1e-09 38.1 9.4 2.2e-05 24.3 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKE41731.1 - 5.8e-09 35.1 10.3 0.031 13.8 0.3 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EKE41731.1 - 3.5e-08 33.6 19.3 0.019 15.2 0.3 6.2 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41731.1 - 5.9e-07 28.8 11.2 0.028 14.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKE41731.1 - 3.8e-06 26.2 0.5 2.5 8.1 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKE41731.1 - 0.00043 20.5 7.0 1.9 9.1 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EKE41731.1 - 0.0029 17.7 21.3 0.34 11.0 0.8 6.5 2 2 4 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3922 PF13059.1 EKE41731.1 - 0.0044 17.1 5.9 0.097 12.8 1.5 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3992) TPR_15 PF13429.1 EKE41731.1 - 0.0085 15.1 3.8 0.096 11.7 0.1 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat DUF915 PF06028.6 EKE41731.1 - 0.014 14.5 0.7 0.028 13.4 0.5 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PPR PF01535.15 EKE41731.1 - 0.026 14.5 2.8 20 5.4 0.0 4.9 5 0 0 5 5 5 0 PPR repeat Fis1_TPR_C PF14853.1 EKE41731.1 - 0.18 11.7 4.5 0.45 10.4 0.0 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EKE41731.1 - 0.21 11.8 13.3 41 4.7 0.0 6.8 7 1 1 8 8 7 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EKE41732.1 - 0.00099 19.0 0.0 0.86 9.6 0.0 4.0 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 EKE41732.1 - 0.0095 15.9 9.6 1.7 8.9 0.2 5.7 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 EKE41732.1 - 0.31 10.9 3.6 9.9 6.1 0.1 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Peptidase_S28 PF05577.7 EKE41733.1 - 8.3e-11 41.1 0.0 1.2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 FANCAA PF15146.1 EKE41733.1 - 0.013 14.4 0.3 0.015 14.2 0.2 1.1 1 0 0 1 1 1 0 Fanconi anemia-associated PP2C_2 PF13672.1 EKE41734.1 - 3e-12 46.4 0.0 4.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE41734.1 - 0.031 13.9 0.0 0.093 12.4 0.0 1.7 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) RasGEF PF00617.14 EKE41735.1 - 2.6e-13 50.1 1.3 5.9e-13 48.9 0.9 1.6 1 0 0 1 1 1 1 RasGEF domain Vps23_core PF09454.5 EKE41735.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Vps23 core domain Ras PF00071.17 EKE41736.1 - 3.5e-52 176.0 2.0 4.1e-52 175.8 1.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41736.1 - 4e-17 62.7 0.9 5.8e-17 62.2 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE41736.1 - 4.5e-11 42.2 1.2 5.7e-11 41.9 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41736.1 - 2.1e-05 24.0 1.8 3.4e-05 23.3 0.7 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE41736.1 - 0.00036 20.4 0.3 0.0006 19.7 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 EKE41736.1 - 0.17 11.4 3.6 0.57 9.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain VSP PF03302.8 EKE41738.1 - 0.06 11.9 107.5 0.087 11.4 56.5 3.3 1 1 1 2 2 2 0 Giardia variant-specific surface protein BRCA-2_OB1 PF09103.5 EKE41739.1 - 4.2e-17 61.9 0.1 1.5e-16 60.1 0.1 2.0 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 RabGAP-TBC PF00566.13 EKE41740.1 - 1.9e-42 145.1 7.1 4.6e-42 143.9 4.9 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2461 PF09365.5 EKE41740.1 - 0.0091 15.4 1.7 0.0091 15.4 1.2 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Arf PF00025.16 EKE41741.1 - 5e-61 204.9 0.7 5.5e-61 204.8 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EKE41741.1 - 1.8e-15 56.5 0.4 9.1e-13 47.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EKE41741.1 - 3.5e-14 52.5 0.1 4e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EKE41741.1 - 1.1e-12 47.6 0.2 1.3e-12 47.3 0.2 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EKE41741.1 - 4.2e-07 30.4 0.1 7.4e-07 29.6 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EKE41741.1 - 2.5e-06 26.7 0.1 2.8e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE41741.1 - 2.9e-06 27.2 0.3 3.8e-06 26.8 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase TRAPPC-Trs85 PF12739.2 EKE41741.1 - 0.0045 15.6 0.0 0.0054 15.4 0.0 1.0 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit FeoB_N PF02421.13 EKE41741.1 - 0.012 14.9 3.5 0.049 12.9 2.4 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4367 PF14285.1 EKE41741.1 - 0.032 13.5 0.6 0.12 11.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4367) GTP_EFTU PF00009.22 EKE41741.1 - 0.037 13.4 0.3 5.2 6.4 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 EKE41742.1 - 4e-58 196.6 0.0 4.9e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41742.1 - 4.4e-28 98.0 0.0 1.2e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41742.1 - 0.00015 20.8 0.0 0.00033 19.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EKE41742.1 - 0.0019 17.8 0.1 0.0047 16.5 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKE41742.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1679 PF07914.6 EKE41742.1 - 0.016 13.8 0.5 0.35 9.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.9 EKE41742.1 - 0.036 13.1 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3945 PF13101.1 EKE41743.1 - 0.021 14.0 0.1 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) DUF1151 PF06625.6 EKE41743.1 - 0.043 13.5 2.6 0.071 12.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) GFO_IDH_MocA PF01408.17 EKE41744.1 - 0.059 13.8 0.2 0.23 12.0 0.1 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_20 PF00728.17 EKE41745.1 - 5.2e-84 282.4 4.8 6.3e-84 282.1 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EKE41745.1 - 1.4e-14 54.8 0.0 3.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EKE41745.1 - 9.5e-06 26.1 0.0 1.8e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ABC2_membrane_3 PF12698.2 EKE41745.1 - 0.055 12.5 0.2 0.093 11.7 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein PRESAN PF09687.5 EKE41745.1 - 0.095 12.7 2.3 0.26 11.3 1.6 1.8 1 0 0 1 1 1 0 Plasmodium RESA N-terminal Sigma70_r1_1 PF03979.9 EKE41745.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 SpoIIP PF07454.6 EKE41747.1 - 0.083 12.0 0.2 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Peptidase_M76 PF09768.4 EKE41748.1 - 0.021 14.2 1.1 0.027 13.9 0.7 1.2 1 0 0 1 1 1 0 Peptidase M76 family RepL PF05732.6 EKE41748.1 - 0.043 13.0 6.6 0.062 12.5 4.5 1.3 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) PM0188 PF11477.3 EKE41748.1 - 0.31 9.8 8.4 0.39 9.4 5.8 1.2 1 0 0 1 1 1 0 Sialyltransferase PMO188 Ssu72 PF04722.8 EKE41748.1 - 0.61 9.3 5.2 0.39 10.0 1.9 1.8 1 1 0 1 1 1 0 Ssu72-like protein MiaE PF06175.6 EKE41748.1 - 2.1 7.6 5.1 0.55 9.5 0.6 1.8 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) NYD-SP28 PF14772.1 EKE41748.1 - 2.9 8.0 7.2 0.98 9.5 1.1 2.2 2 0 0 2 2 2 0 Sperm tail COX4 PF02936.9 EKE41749.1 - 0.021 14.5 0.7 0.05 13.3 0.5 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Sec8_exocyst PF04048.9 EKE41749.1 - 0.024 14.2 8.0 0.11 12.0 1.6 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Phage_int_SAM_5 PF13102.1 EKE41749.1 - 0.039 13.9 7.0 0.058 13.3 0.9 2.5 2 0 0 2 2 2 0 Phage integrase SAM-like domain DUF482 PF04339.7 EKE41749.1 - 0.055 12.3 0.7 0.084 11.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 BSP PF04450.7 EKE41749.1 - 0.06 12.8 0.3 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase of plants and bacteria WH2 PF02205.15 EKE41749.1 - 0.072 12.7 0.2 0.072 12.7 0.1 2.7 3 0 0 3 3 3 0 WH2 motif YniB PF14002.1 EKE41751.1 - 0.13 11.7 3.7 0.25 10.7 2.6 1.4 1 0 0 1 1 1 0 YniB-like protein Desmo_N PF06771.6 EKE41751.1 - 1.8 8.5 7.4 0.14 12.0 1.2 2.0 2 1 0 2 2 2 0 Viral Desmoplakin N-terminus DUF2547 PF10818.3 EKE41751.1 - 7.3 7.2 10.5 4.1 8.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2547) HA2 PF04408.18 EKE41752.1 - 2.2e-29 101.4 0.0 2.2e-29 101.4 0.0 2.6 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EKE41752.1 - 2.4e-28 98.2 0.0 8.1e-28 96.5 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EKE41752.1 - 3.4e-12 46.0 0.1 1.6e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE41752.1 - 3.1e-07 30.0 0.1 3.1e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE41752.1 - 1.4e-06 28.5 0.1 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKE41752.1 - 0.00014 21.7 1.4 0.0059 16.5 0.7 3.6 3 1 0 3 3 3 1 AAA domain T2SE PF00437.15 EKE41752.1 - 0.00077 18.4 0.5 0.012 14.4 0.2 2.7 3 1 0 3 3 3 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EKE41752.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ABC_tran PF00005.22 EKE41752.1 - 0.0046 17.2 0.7 0.0046 17.2 0.5 3.5 1 1 1 2 2 2 1 ABC transporter AAA_30 PF13604.1 EKE41752.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKE41752.1 - 0.19 11.4 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Pkinase_Tyr PF07714.12 EKE41753.1 - 2e-26 92.6 0.0 2.6e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41753.1 - 4.6e-24 84.9 0.1 7.3e-24 84.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Tubulin PF00091.20 EKE41754.1 - 1.3e-68 231.0 0.0 3.3e-68 229.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKE41754.1 - 1.4e-42 144.6 0.0 2.2e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EKE41754.1 - 9.3e-06 25.6 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EKE41754.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain RecT PF03837.9 EKE41754.1 - 0.028 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 RecT family PALP PF00291.20 EKE41755.1 - 6.1e-70 235.8 0.7 7.3e-70 235.6 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.1 EKE41755.1 - 2.5e-06 27.7 0.9 2.2e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 ACT domain DegT_DnrJ_EryC1 PF01041.12 EKE41755.1 - 0.036 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Radical_SAM PF04055.16 EKE41755.1 - 0.037 14.1 0.0 0.97 9.5 0.0 2.4 2 0 0 2 2 2 0 Radical SAM superfamily CDC45 PF02724.9 EKE41756.1 - 8.6e-95 318.0 9.0 3.1e-70 236.9 2.9 2.7 1 1 1 2 2 2 2 CDC45-like protein Head-tail_con PF12236.3 EKE41756.1 - 0.05 11.9 0.0 0.1 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Bac_small_YrzI PF09501.5 EKE41757.1 - 0.014 15.2 3.1 0.026 14.4 0.7 2.7 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DUF4239 PF14023.1 EKE41757.1 - 0.029 13.7 2.3 0.048 13.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) zf-DHHC PF01529.15 EKE41760.1 - 8.7e-24 83.8 13.2 8.7e-24 83.8 9.2 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase BSD PF03909.12 EKE41761.1 - 0.00021 20.9 0.6 0.00047 19.8 0.4 1.6 1 0 0 1 1 1 1 BSD domain TLD PF07534.11 EKE41762.1 - 1.9e-26 92.7 0.5 2.2e-26 92.4 0.4 1.1 1 0 0 1 1 1 1 TLD CsoSCA PF08936.5 EKE41762.1 - 0.15 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase RabGAP-TBC PF00566.13 EKE41763.1 - 5.7e-28 97.8 6.9 5.7e-28 97.8 4.8 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GF_recep_IV PF14843.1 EKE41764.1 - 0.037 13.6 1.7 0.059 12.9 1.2 1.3 1 0 0 1 1 1 0 Growth factor receptor domain IV Ribosomal_S17e PF00833.13 EKE41764.1 - 0.06 13.0 0.6 0.1 12.3 0.2 1.6 1 1 0 1 1 1 0 Ribosomal S17 Pkinase PF00069.20 EKE41765.1 - 3.2e-70 236.2 0.0 4.5e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41765.1 - 1.4e-35 122.6 0.0 2e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE41765.1 - 1.7e-14 53.8 0.2 4.2e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EKE41765.1 - 3.3e-08 32.8 0.0 9.2e-08 31.3 0.0 1.6 1 1 0 2 2 2 1 Kinase-like PH_3 PF14593.1 EKE41765.1 - 9.3e-07 28.6 0.5 2.3e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EKE41765.1 - 5.7e-05 23.1 0.2 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EKE41765.1 - 0.0002 21.5 1.2 0.001 19.2 0.8 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.19 EKE41765.1 - 0.00033 21.1 7.1 0.00095 19.6 3.4 2.5 2 1 0 2 2 2 1 Protein kinase C terminal domain Mcp5_PH PF12814.2 EKE41765.1 - 0.039 13.8 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Pet191_N PF10203.4 EKE41766.1 - 0.86 9.6 9.4 1.8 8.6 0.4 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 AAA PF00004.24 EKE41767.1 - 1.1e-42 145.3 0.0 2.7e-42 144.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKE41767.1 - 1.7e-07 31.0 0.1 7e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKE41767.1 - 6.9e-06 26.0 0.4 2.2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EKE41767.1 - 1.1e-05 24.6 0.0 2.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKE41767.1 - 1.6e-05 25.0 0.8 0.0042 17.2 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EKE41767.1 - 2.4e-05 24.4 0.7 0.00018 21.5 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EKE41767.1 - 0.00079 18.4 0.0 0.0076 15.1 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EKE41767.1 - 0.00091 18.5 0.1 0.0073 15.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.1 EKE41767.1 - 0.00092 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EKE41767.1 - 0.0022 17.4 0.3 0.063 12.7 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EKE41767.1 - 0.0025 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EKE41767.1 - 0.0039 16.9 0.1 0.0083 15.8 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EKE41767.1 - 0.0057 16.6 0.0 0.037 14.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EKE41767.1 - 0.006 16.0 1.1 0.23 10.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EKE41767.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EKE41767.1 - 0.014 14.4 4.1 0.036 13.1 0.1 2.6 2 1 1 3 3 3 0 KaiC AAA_3 PF07726.6 EKE41767.1 - 0.017 14.7 0.2 0.065 12.8 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EKE41767.1 - 0.02 14.4 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EKE41767.1 - 0.022 14.6 0.2 0.073 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EKE41767.1 - 0.027 13.5 0.7 0.045 12.8 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EKE41767.1 - 0.032 15.0 0.6 0.13 13.0 0.1 2.4 2 1 1 3 3 1 0 AAA domain AAA_30 PF13604.1 EKE41767.1 - 0.056 13.0 1.3 0.06 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EKE41767.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EKE41767.1 - 0.098 12.3 0.1 5.8 6.5 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.1 EKE41767.1 - 0.14 11.6 3.0 0.21 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF972 PF06156.8 EKE41767.1 - 0.45 10.8 4.9 0.77 10.1 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) eIF2A PF08662.6 EKE41768.1 - 3e-34 118.4 1.8 1.7e-32 112.7 1.3 2.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Myb_DNA-binding PF00249.26 EKE41769.1 - 2.8e-21 75.2 0.7 2.8e-13 49.7 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE41769.1 - 7.6e-17 61.1 0.2 1.2e-10 41.3 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EKE41769.1 - 0.00062 19.5 0.4 1.6 8.6 0.0 3.0 1 1 1 2 2 2 2 Rap1 Myb domain SLIDE PF09111.5 EKE41769.1 - 0.0048 16.6 0.2 0.2 11.3 0.1 2.2 1 1 1 2 2 2 1 SLIDE ADH_N PF08240.7 EKE41770.1 - 4.3e-28 97.2 4.1 4.3e-28 97.2 2.8 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKE41770.1 - 1.8e-18 66.3 0.0 3.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EKE41770.1 - 0.0089 16.4 0.1 0.16 12.4 0.0 2.8 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE41770.1 - 0.0092 16.5 0.0 0.019 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EKE41770.1 - 0.014 14.7 0.3 0.036 13.4 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FH2 PF02181.18 EKE41771.1 - 2.3e-87 293.2 11.1 2.3e-87 293.2 7.7 3.7 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EKE41771.1 - 9.8e-34 116.4 13.8 9.8e-34 116.4 9.6 2.9 1 1 1 2 2 1 1 Diaphanous FH3 Domain Drf_FH1 PF06346.7 EKE41771.1 - 1.6e-09 37.5 123.2 2.9e-09 36.6 85.4 1.4 1 0 0 1 1 1 1 Formin Homology Region 1 Laminin_II PF06009.7 EKE41771.1 - 7.5e-05 22.5 8.7 7.5e-05 22.5 6.0 3.9 4 0 0 4 4 4 2 Laminin Domain II IncA PF04156.9 EKE41771.1 - 0.0011 18.6 22.0 0.21 11.1 11.9 4.1 4 1 0 4 4 4 1 IncA protein Prok-RING_1 PF14446.1 EKE41771.1 - 0.014 15.1 6.6 0.028 14.1 4.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Phage_lysis PF03245.8 EKE41771.1 - 0.022 14.7 0.2 0.022 14.7 0.1 2.8 3 1 0 3 3 2 0 Bacteriophage Rz lysis protein C1_1 PF00130.17 EKE41771.1 - 0.029 14.1 10.7 0.054 13.2 7.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Reo_sigmaC PF04582.7 EKE41771.1 - 0.53 9.4 6.5 0.25 10.4 1.8 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF869 PF05911.6 EKE41771.1 - 1.7 6.7 46.8 0.28 9.3 21.4 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Tnp_zf-ribbon_2 PF13842.1 EKE41771.1 - 2 8.9 12.2 4.8 7.6 8.5 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2968 PF11180.3 EKE41771.1 - 2.1 7.6 12.3 0.18 11.1 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) MCPsignal PF00015.16 EKE41771.1 - 3.6 7.0 19.2 0.21 11.1 5.2 3.3 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TP6A_N PF04406.9 EKE41773.1 - 9.4e-14 50.8 0.4 9.4e-14 50.8 0.3 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase TLD PF07534.11 EKE41774.1 - 0.00015 21.7 0.4 0.0002 21.3 0.3 1.2 1 0 0 1 1 1 1 TLD Mem_trans PF03547.13 EKE41775.1 - 0.00019 19.8 18.7 0.0011 17.3 13.0 2.0 1 1 0 1 1 1 1 Membrane transport protein Peptidase_M50 PF02163.17 EKE41775.1 - 2.6 6.9 7.1 0.74 8.7 1.5 2.2 2 0 0 2 2 2 0 Peptidase family M50 RNA_pol_Rpb1_5 PF04998.12 EKE41776.1 - 1.5e-91 306.5 2.3 2.3e-91 305.9 1.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EKE41776.1 - 6.8e-80 268.8 0.2 6.8e-80 268.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EKE41776.1 - 1.4e-67 226.7 0.6 4.1e-67 225.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EKE41776.1 - 8.4e-31 106.8 0.1 1.7e-29 102.6 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EKE41776.1 - 8.2e-28 96.3 2.1 2.4e-27 94.7 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Pkinase PF00069.20 EKE41777.1 - 1.1e-13 50.9 3.1 2.9e-13 49.5 1.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41777.1 - 1e-06 28.0 0.8 4e-05 22.8 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.15 EKE41777.1 - 0.0057 16.2 4.8 0.013 15.0 3.2 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EKE41777.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Imm1 PF14430.1 EKE41779.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 Immunity protein Imm1 DUF1617 PF07761.7 EKE41780.1 - 0.027 14.5 0.5 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) TPR_11 PF13414.1 EKE41781.1 - 4.9e-24 83.7 4.0 1.6e-16 59.7 1.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EKE41781.1 - 8.9e-15 53.3 9.6 2.2e-06 27.1 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41781.1 - 1.7e-09 37.1 5.4 0.0019 18.2 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKE41781.1 - 5.3e-09 35.3 12.4 3.7e-05 23.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKE41781.1 - 5.9e-05 22.8 0.3 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EKE41781.1 - 7.5e-05 22.5 4.5 0.00079 19.3 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41781.1 - 0.0016 19.0 0.0 0.2 12.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EKE41781.1 - 0.0021 17.8 0.0 0.1 12.4 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKE41781.1 - 0.0036 17.8 0.0 0.022 15.3 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE41781.1 - 0.0042 16.7 11.9 0.023 14.4 0.2 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE41781.1 - 0.0058 16.9 0.1 0.089 13.1 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.11 EKE41781.1 - 0.12 12.2 1.9 4.9 7.0 0.1 2.9 1 1 1 2 2 2 0 Tc5 transposase DNA-binding domain Ribosomal_S8 PF00410.14 EKE41781.1 - 1 9.2 4.1 0.42 10.4 0.7 1.9 2 0 0 2 2 2 0 Ribosomal protein S8 DUF3492 PF11997.3 EKE41781.1 - 2.8 7.3 7.5 6.5 6.2 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) VPS9 PF02204.13 EKE41782.1 - 7.9e-11 41.9 6.2 7.9e-11 41.9 4.3 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain UBX PF00789.15 EKE41783.1 - 7.6e-06 25.9 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 UBX domain Mem_trans PF03547.13 EKE41783.1 - 0.63 8.2 3.5 0.63 8.2 2.5 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF913 PF06025.7 EKE41783.1 - 0.88 8.2 7.2 1.2 7.8 5.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_UL95 PF03038.9 EKE41783.1 - 0.94 8.2 11.3 1.5 7.6 7.8 1.2 1 0 0 1 1 1 0 UL95 family AF-4 PF05110.8 EKE41783.1 - 3.6 5.3 17.1 4 5.1 11.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PLRV_ORF5 PF01690.12 EKE41783.1 - 4 6.4 13.6 4.8 6.2 9.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2252 PF10009.4 EKE41783.1 - 8.3 5.1 16.4 11 4.8 11.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) zf-H2C2 PF09337.5 EKE41784.1 - 0.046 13.1 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger C9orf72-like PF15019.1 EKE41785.1 - 0.0025 17.1 2.9 0.0031 16.8 2.0 1.1 1 0 0 1 1 1 1 C9orf72-like protein family HN PF00423.14 EKE41785.1 - 0.011 14.0 3.9 0.012 13.9 2.7 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Hormone_1 PF00103.15 EKE41785.1 - 0.032 13.5 2.0 0.047 13.0 1.4 1.3 1 0 0 1 1 1 0 Somatotropin hormone family B5 PF03484.10 EKE41785.1 - 0.14 12.0 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetase B5 domain ATP-synt_G PF04718.10 EKE41785.1 - 2.4 8.8 6.3 2.7 8.6 1.9 2.3 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit MpPF26 PF07666.6 EKE41786.1 - 0.052 13.4 6.2 0.084 12.7 2.6 2.0 2 0 0 2 2 2 0 M penetrans paralogue family 26 ELMO_CED12 PF04727.8 EKE41786.1 - 0.1 12.1 0.2 0.16 11.4 0.1 1.4 1 1 0 1 1 1 0 ELMO/CED-12 family WD40 PF00400.27 EKE41787.1 - 0.00037 20.2 1.3 0.12 12.3 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EKE41787.1 - 0.003 17.0 0.0 0.11 11.9 0.0 3.3 3 1 0 3 3 3 1 PQQ-like domain Nup160 PF11715.3 EKE41787.1 - 0.02 13.0 0.7 0.13 10.3 0.1 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 RRM_1 PF00076.17 EKE41788.1 - 9.5e-07 28.3 0.0 3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41788.1 - 0.0003 20.7 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE41788.1 - 0.00079 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EKE41788.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fib_alpha PF08702.5 EKE41788.1 - 1.2 9.2 6.7 2.1 8.4 4.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Rad10 PF03834.9 EKE41789.1 - 4.1e-07 29.5 1.0 1.1e-06 28.2 0.7 1.7 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.2 EKE41789.1 - 0.00035 20.3 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EKE41789.1 - 0.0004 20.4 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain Ribosomal_S13 PF00416.17 EKE41789.1 - 0.022 15.2 1.1 0.046 14.1 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Peptidase_C1 PF00112.18 EKE41790.1 - 6.4e-41 140.6 1.5 8.6e-41 140.2 1.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EKE41790.1 - 0.046 12.2 0.1 0.095 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase C1-like family RAI16-like PF10257.4 EKE41790.1 - 0.075 11.9 0.2 2 7.2 0.0 2.0 1 1 1 2 2 2 0 Retinoic acid induced 16-like protein Utp21 PF04192.7 EKE41793.1 - 5.7e-18 64.8 6.8 2.5e-17 62.8 4.7 1.9 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EKE41793.1 - 1e-08 34.7 10.8 5.8e-06 25.9 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EKE41793.1 - 6.3e-06 24.7 0.1 1.7e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain Utp12 PF04003.7 EKE41793.1 - 8.9e-05 22.3 0.1 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family PQQ_2 PF13360.1 EKE41793.1 - 0.00097 18.6 0.0 0.16 11.4 0.0 3.2 2 2 0 2 2 2 1 PQQ-like domain DUF3508 PF12018.3 EKE41793.1 - 0.0026 16.7 1.3 0.0058 15.6 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) Apc4_WD40 PF12894.2 EKE41793.1 - 0.042 13.3 0.0 10 5.6 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain UTP15_C PF09384.5 EKE41793.1 - 0.049 13.3 0.4 0.096 12.3 0.3 1.4 1 0 0 1 1 1 0 UTP15 C terminal Bactofilin PF04519.8 EKE41793.1 - 0.14 12.1 0.7 2.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Polymer-forming cytoskeletal HSP70 PF00012.15 EKE41794.1 - 8.6e-239 793.4 11.0 1e-238 793.2 7.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE41794.1 - 5.8e-15 54.6 3.7 1.4e-13 50.1 0.0 2.6 3 0 0 3 3 3 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EKE41794.1 - 0.0057 15.8 1.3 0.031 13.3 0.0 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 EKE41794.1 - 0.011 14.6 0.1 0.27 10.0 0.0 2.5 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 EKE41794.1 - 0.032 13.1 0.9 0.077 11.9 0.0 2.0 2 0 0 2 2 2 0 StbA protein FGGY_C PF02782.11 EKE41794.1 - 0.042 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1510 PF07423.6 EKE41795.1 - 0.009 15.3 12.9 0.01 15.2 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SH3BP5 PF05276.9 EKE41796.1 - 0.37 10.0 1.7 0.43 9.8 1.2 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) PNTB PF02233.11 EKE41797.1 - 5e-39 134.3 12.0 6.4e-39 134.0 8.3 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit PP2C_2 PF13672.1 EKE41798.1 - 1.5e-06 27.7 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 EKE41799.1 - 1.6e-08 34.0 0.0 4e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain PARP_reg PF02877.9 EKE41799.1 - 0.11 12.2 0.6 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Thioredoxin PF00085.15 EKE41800.1 - 6.5e-17 61.1 0.0 7.7e-17 60.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKE41800.1 - 0.00089 19.3 0.7 0.24 11.5 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EKE41800.1 - 0.002 17.7 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE41800.1 - 0.0022 18.1 0.4 0.024 14.8 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.11 EKE41800.1 - 0.014 14.9 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 TrbC_Ftype PF09673.5 EKE41800.1 - 0.024 14.2 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DUF953 PF06110.6 EKE41800.1 - 0.025 14.0 0.1 0.17 11.3 0.1 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.1 EKE41800.1 - 0.03 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.19 EKE41800.1 - 0.087 12.8 0.2 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Glutaredoxin DUF3912 PF13051.1 EKE41800.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) AhpC-TSA PF00578.16 EKE41800.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family RhoGEF PF00621.15 EKE41801.1 - 1.5e-32 112.9 4.7 1.5e-32 112.9 3.3 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF4200 PF13863.1 EKE41802.1 - 0.0036 17.2 30.4 0.0036 17.2 21.1 3.8 1 1 3 4 4 3 1 Domain of unknown function (DUF4200) Matrilin_ccoil PF10393.4 EKE41802.1 - 0.03 13.6 1.4 0.03 13.6 1.0 3.6 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin WEMBL PF05701.6 EKE41802.1 - 0.073 11.5 42.5 0.086 11.2 16.3 2.1 1 1 0 2 2 2 0 Weak chloroplast movement under blue light DUF4618 PF15397.1 EKE41802.1 - 0.08 12.2 34.1 4.8 6.4 23.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 EKE41802.1 - 0.14 11.9 6.4 0.073 12.9 0.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EKE41802.1 - 0.22 11.7 10.3 0.074 13.3 3.2 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EKE41802.1 - 0.44 10.1 44.2 0.69 9.4 16.5 2.2 1 1 0 2 2 2 0 IncA protein ADIP PF11559.3 EKE41802.1 - 0.51 10.2 40.8 0.28 11.0 0.9 3.6 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 EKE41802.1 - 0.53 9.7 49.3 0.2 11.1 16.7 2.7 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Mnd1 PF03962.10 EKE41802.1 - 0.56 9.8 35.7 0.44 10.1 6.3 2.3 1 1 0 2 2 2 0 Mnd1 family Imm42 PF15601.1 EKE41802.1 - 0.65 9.4 6.8 7.1 6.0 0.3 2.7 1 1 0 2 2 2 0 Immunity protein 42 DUF3153 PF11353.3 EKE41802.1 - 1.2 8.5 9.4 0.44 9.9 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Fungal_trans_2 PF11951.3 EKE41802.1 - 1.4 7.4 6.5 1.2 7.6 0.2 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Rootletin PF15035.1 EKE41802.1 - 1.5 8.7 35.8 0.052 13.5 10.7 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF342 PF03961.8 EKE41802.1 - 2.3 6.5 36.2 0.78 8.0 8.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3698 PF12479.3 EKE41802.1 - 2.9 8.0 17.4 2.2 8.4 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3698) AKNA PF12443.3 EKE41802.1 - 4.2 7.4 26.9 2.6 8.1 2.2 3.7 1 1 1 3 3 3 0 AT-hook-containing transcription factor UPF0184 PF03670.8 EKE41802.1 - 4.4 7.5 10.2 1.3 9.2 3.0 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) DUF3584 PF12128.3 EKE41802.1 - 5.1 4.2 37.4 15 2.7 25.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ApoO PF09769.4 EKE41802.1 - 5.7 6.6 8.4 0.38 10.4 0.2 2.3 1 1 0 2 2 2 0 Apolipoprotein O GAS PF13851.1 EKE41802.1 - 7.6 5.6 46.2 3.5 6.7 17.0 3.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EKE41802.1 - 7.7 5.0 42.4 3.1 6.3 9.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein GBP_C PF02841.9 EKE41802.1 - 7.9 5.5 36.4 0.33 10.0 6.1 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain CENP-F_leu_zip PF10473.4 EKE41802.1 - 8.4 6.2 47.7 0.15 11.9 0.8 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 EKE41802.1 - 8.5 5.7 16.7 0.74 9.1 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) AAA_13 PF13166.1 EKE41802.1 - 9.7 4.4 41.0 1.6e+02 0.5 28.2 2.0 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EKE41803.1 - 1.4e-44 151.5 0.0 1.4e-44 151.5 0.0 3.2 4 1 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE41803.1 - 4.8e-24 84.0 0.0 1.2e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EKE41803.1 - 0.0026 17.5 10.8 0.0026 17.5 7.5 2.5 1 1 1 2 2 2 1 DBP10CT (NUC160) domain AAA_19 PF13245.1 EKE41803.1 - 0.17 11.6 0.0 0.62 9.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain Ras PF00071.17 EKE41804.1 - 1.6e-33 115.4 0.2 1.9e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41804.1 - 1.7e-13 51.1 0.1 2.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41804.1 - 1.5e-11 43.8 0.0 1.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41804.1 - 2.1e-09 37.0 0.0 4.4e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE41804.1 - 2.2e-09 37.2 0.1 3.7e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE41804.1 - 4.8e-06 25.9 0.4 8.2e-06 25.1 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EKE41804.1 - 0.0007 18.8 1.3 0.00097 18.4 0.1 1.8 1 1 1 2 2 2 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EKE41804.1 - 0.029 14.0 0.2 0.04 13.6 0.2 1.4 1 1 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EKE41804.1 - 0.032 13.7 0.2 0.18 11.3 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EKE41804.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TRAPP PF04051.11 EKE41805.1 - 2e-24 85.8 0.1 2.4e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pkinase PF00069.20 EKE41806.1 - 1.6e-70 237.2 0.5 2.2e-70 236.8 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41806.1 - 5.9e-40 136.9 0.2 8.6e-40 136.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE41806.1 - 2.6e-06 26.6 0.0 9.5e-06 24.7 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EKE41806.1 - 0.00078 19.0 0.4 0.0047 16.5 0.1 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKE41806.1 - 0.012 15.4 0.1 0.24 11.1 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EKE41806.1 - 0.015 14.3 0.1 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec23_trunk PF04811.10 EKE41807.1 - 8.2e-17 61.3 0.6 8.2e-17 61.3 0.4 2.9 2 2 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EKE41807.1 - 1.2e-12 48.2 0.0 2.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EKE41807.1 - 6.1e-12 44.8 3.8 1.7e-11 43.4 2.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger bZIP_1 PF00170.16 EKE41808.1 - 0.0012 18.7 34.7 0.01 15.7 2.2 5.2 4 1 1 5 5 5 2 bZIP transcription factor DUF4201 PF13870.1 EKE41808.1 - 0.0013 18.1 20.5 0.0013 18.1 14.2 3.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4201) TetR_C_4 PF08359.6 EKE41808.1 - 0.023 14.6 1.6 0.023 14.6 1.1 2.9 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region HOOK PF05622.7 EKE41808.1 - 0.081 10.7 30.9 0.13 10.0 21.4 1.3 1 0 0 1 1 1 0 HOOK protein KLRAQ PF10205.4 EKE41808.1 - 0.33 11.0 25.8 1.9 8.5 7.9 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 EKE41808.1 - 1 8.8 37.4 5.3e+02 0.0 26.0 2.8 1 1 0 1 1 1 0 IncA protein NUDIX_2 PF13869.1 EKE41808.1 - 1.3 8.3 11.9 0.74 9.1 6.4 2.0 1 1 1 2 2 2 0 Nucleotide hydrolase DUF2968 PF11180.3 EKE41808.1 - 1.7 8.0 24.1 0.039 13.3 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF641 PF04859.7 EKE41808.1 - 1.9 8.2 31.3 0.16 11.7 7.3 4.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) BDV_P24 PF06595.6 EKE41808.1 - 2 8.1 13.3 2.1 8.0 8.3 1.7 1 1 0 1 1 1 0 Borna disease virus P24 protein DUF2422 PF10337.4 EKE41808.1 - 2.1 7.0 12.8 2.7 6.6 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) AAA_27 PF13514.1 EKE41808.1 - 2.3 5.7 22.7 3.2 5.3 15.7 1.2 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 EKE41808.1 - 4.3 7.2 32.9 1.5 8.6 3.0 4.9 2 2 1 4 4 4 0 Basic region leucine zipper Atg14 PF10186.4 EKE41808.1 - 4.8 6.0 35.2 0.4 9.5 3.4 3.3 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EKE41808.1 - 5.4 5.9 37.0 0.24 10.3 4.4 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-Q PF13094.1 EKE41808.1 - 6.6 6.7 37.8 1.7 8.6 11.2 3.1 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2205 PF10224.4 EKE41808.1 - 7.2 6.2 36.4 0.25 10.9 7.5 4.0 2 1 2 4 4 3 0 Predicted coiled-coil protein (DUF2205) DUF4200 PF13863.1 EKE41808.1 - 8.2 6.3 42.3 0.061 13.2 9.2 3.7 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 EKE41808.1 - 9 6.0 38.9 0.24 11.1 4.5 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) HisKA PF00512.20 EKE41808.1 - 9.7 6.2 7.2 0.47 10.4 0.2 2.4 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DSPc PF00782.15 EKE41809.1 - 9e-33 112.6 0.0 2.3e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 EKE41809.1 - 3e-09 36.2 13.5 0.00011 21.7 0.2 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE41809.1 - 1.7e-07 30.8 14.1 7.3e-06 25.6 2.4 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EKE41809.1 - 2.6e-07 29.7 2.3 2.6 8.6 0.0 5.3 5 0 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EKE41809.1 - 6.9e-07 28.4 10.1 0.77 10.0 0.0 5.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 EKE41809.1 - 6.2e-06 25.7 10.3 0.67 10.1 0.0 5.4 4 1 1 5 5 5 2 Leucine Rich repeat Y_phosphatase PF00102.22 EKE41809.1 - 0.0094 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EKE41809.1 - 0.021 13.6 0.8 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 Initiator tRNA phosphoribosyl transferase Ras PF00071.17 EKE41810.1 - 1.3e-32 112.4 0.2 1.7e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41810.1 - 1.4e-14 54.5 0.0 2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41810.1 - 2.9e-12 46.1 0.0 4.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41810.1 - 1.7e-07 30.8 0.1 1e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKE41810.1 - 1.4e-06 27.8 0.0 2.5e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EKE41810.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE41810.1 - 2.5e-05 23.6 0.0 0.00093 18.5 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EKE41810.1 - 8.3e-05 21.8 0.1 0.00012 21.3 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE41810.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EKE41810.1 - 0.043 13.0 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit KaiC PF06745.8 EKE41810.1 - 0.11 11.6 0.2 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 EKE41810.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EKE41810.1 - 0.12 12.3 1.2 0.68 9.8 0.7 2.1 1 1 1 2 2 2 0 AAA domain DNA_pol_A_exo1 PF01612.15 EKE41811.1 - 7.2e-13 48.3 0.1 1.7e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease FtsX PF02687.16 EKE41812.1 - 8.3e-27 93.3 44.4 2.5e-16 59.5 13.3 4.9 4 1 1 5 5 5 3 FtsX-like permease family PI3_PI4_kinase PF00454.22 EKE41814.1 - 2.7e-37 128.4 0.1 3.8e-36 124.7 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EKE41814.1 - 1.4e-20 73.2 0.4 1.4e-20 73.2 0.3 3.2 4 0 0 4 4 4 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) NAD_binding_5 PF07994.7 EKE41814.1 - 0.003 17.1 1.1 0.0093 15.4 0.7 1.8 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase RRM_6 PF14259.1 EKE41815.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 EKE41816.1 - 4.2e-07 29.9 0.1 8.6e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 FHA domain FlgM PF04316.8 EKE41816.1 - 0.0049 16.7 0.2 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM Peptidase_S49_N PF08496.5 EKE41816.1 - 1.6 8.5 6.8 2.7 7.7 4.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ICL PF00463.16 EKE41817.1 - 0.082 11.0 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family SIR2 PF02146.12 EKE41820.1 - 1e-49 168.6 0.0 3.7e-49 166.8 0.0 1.8 2 0 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.17 EKE41820.1 - 0.1 12.3 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HSF_DNA-bind PF00447.12 EKE41821.1 - 7e-06 26.1 5.5 1e-05 25.6 2.7 2.2 1 1 0 1 1 1 1 HSF-type DNA-binding DUF3676 PF12429.3 EKE41821.1 - 0.22 11.1 5.3 0.3 10.6 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) Hom_end_hint PF05203.11 EKE41821.1 - 8.1 6.1 8.5 5 6.7 4.7 1.5 2 0 0 2 2 2 0 Hom_end-associated Hint SNF2_assoc PF08455.5 EKE41822.1 - 0.0099 14.4 0.3 0.018 13.6 0.2 1.4 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated Rogdi_lz PF10259.4 EKE41822.1 - 0.016 14.3 6.5 0.18 10.9 4.4 2.6 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein Rifin_STEVOR PF02009.11 EKE41823.1 - 3.2 7.3 9.6 0.6 9.7 3.3 2.1 2 0 0 2 2 2 0 Rifin/stevor family PI3_PI4_kinase PF00454.22 EKE41824.1 - 3.8e-43 147.6 1.4 1.1e-42 146.1 1.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EKE41824.1 - 3e-35 121.0 0.3 6.8e-35 119.9 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EKE41824.1 - 1.3e-15 57.4 0.3 7.7e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Acetyltransf_1 PF00583.19 EKE41826.1 - 1.4e-07 31.4 0.0 7.6e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE41826.1 - 4.5e-06 26.7 0.9 4.6e-05 23.4 0.6 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE41826.1 - 1e-05 25.6 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE41826.1 - 2e-05 24.4 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKE41826.1 - 0.0023 17.9 5.7 0.051 13.5 0.3 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKE41826.1 - 0.03 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Zn_ribbon_2 PF12674.2 EKE41826.1 - 1.4 9.2 6.9 0.75 10.1 2.3 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain Yip1 PF04893.12 EKE41827.1 - 0.027 13.9 0.5 0.035 13.5 0.3 1.1 1 0 0 1 1 1 0 Yip1 domain DUF2985 PF11204.3 EKE41827.1 - 0.031 14.0 3.2 0.67 9.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) DUF2207 PF09972.4 EKE41827.1 - 0.038 12.5 0.9 0.043 12.3 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OppC_N PF12911.2 EKE41827.1 - 0.11 11.8 0.1 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MpPF26 PF07666.6 EKE41827.1 - 3.8 7.4 8.0 11 5.9 0.2 2.0 1 1 0 2 2 2 0 M penetrans paralogue family 26 Mon1 PF03164.9 EKE41828.1 - 2.1e-51 174.8 10.8 2.4e-51 174.6 7.5 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Peptidase_C39 PF03412.10 EKE41828.1 - 0.038 13.7 0.5 0.038 13.7 0.4 1.8 2 0 0 2 2 2 0 Peptidase C39 family DUF2305 PF10230.4 EKE41829.1 - 1.6e-36 126.1 2.4 2.6e-36 125.4 1.6 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EKE41829.1 - 0.00016 21.4 0.0 0.00033 20.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKE41829.1 - 0.00054 19.9 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EKE41829.1 - 0.0014 18.3 0.0 0.0098 15.6 0.0 2.1 2 0 0 2 2 2 1 Cutinase DUF900 PF05990.7 EKE41829.1 - 0.0065 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PS_pyruv_trans PF04230.8 EKE41829.1 - 0.014 15.1 0.5 2.2 7.9 0.0 2.5 3 0 0 3 3 3 0 Polysaccharide pyruvyl transferase Lipase_3 PF01764.20 EKE41829.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 EKE41829.1 - 0.07 12.4 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 EKE41829.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.20 EKE41830.1 - 3.3e-43 147.7 0.1 8e-43 146.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41830.1 - 1.3e-27 96.4 0.0 3.4e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Mak10 PF04112.8 EKE41832.1 - 1.8e-06 27.2 2.2 2.5e-05 23.5 1.5 2.3 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ras PF00071.17 EKE41833.1 - 1e-36 125.8 0.4 1.2e-36 125.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41833.1 - 4.6e-12 46.4 0.2 8.8e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE41833.1 - 1.3e-09 37.4 0.1 1.6e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41833.1 - 0.00012 21.5 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE41833.1 - 0.0098 15.0 0.1 0.012 14.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF976 PF06162.7 EKE41833.1 - 0.041 13.3 0.3 0.19 11.2 0.1 2.0 1 1 1 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF976) VSP PF03302.8 EKE41834.1 - 8.4e-06 24.6 112.3 2.4e-05 23.1 25.1 5.0 1 1 5 6 6 6 4 Giardia variant-specific surface protein MIF4G PF02854.14 EKE41835.1 - 1.5e-20 73.5 6.7 1.5e-20 73.5 4.6 2.6 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EKE41835.1 - 1.5e-14 53.6 3.7 3.8e-14 52.3 2.6 1.8 1 0 0 1 1 1 1 MA3 domain DUF2381 PF09544.5 EKE41835.1 - 0.24 10.4 0.6 0.56 9.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) Ribonuclease_P PF00825.13 EKE41836.1 - 0.0067 16.3 1.8 0.0067 16.3 1.3 2.2 2 0 0 2 2 2 1 Ribonuclease P CHB_HEX_C PF03174.8 EKE41836.1 - 0.024 14.4 0.0 0.088 12.6 0.0 1.9 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 EKE41836.1 - 0.031 14.0 0.5 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Baculo_PEP_C PF04513.7 EKE41837.1 - 0.043 13.6 13.1 1.3 8.8 0.2 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2782 PF11191.3 EKE41837.1 - 1.8 8.5 4.5 2.4 8.1 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2782) Tweety PF04906.8 EKE41837.1 - 2.2 6.5 11.5 1.6 7.0 1.2 3.2 1 1 1 3 3 3 0 Tweety Complex1_LYR_1 PF13232.1 EKE41837.1 - 3 8.1 7.1 0.44 10.7 0.3 2.9 3 1 1 4 4 4 0 Complex1_LYR-like Gly_radical PF01228.16 EKE41837.1 - 4.5 7.6 8.6 2.1 8.7 1.9 2.7 2 2 0 2 2 2 0 Glycine radical VPS9 PF02204.13 EKE41838.1 - 2e-09 37.4 0.8 2e-09 37.4 0.6 2.0 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain ADK PF00406.17 EKE41839.1 - 9.4e-44 148.9 0.0 1.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 EKE41839.1 - 7.6e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE41839.1 - 7.9e-08 32.6 0.2 1.7e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE41839.1 - 2.5e-07 31.5 0.0 3.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EKE41839.1 - 0.00044 19.6 0.7 0.022 14.1 0.0 2.4 1 1 2 3 3 3 1 Thymidylate kinase SRP54 PF00448.17 EKE41839.1 - 0.02 14.3 0.1 0.068 12.6 0.0 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EKE41839.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin tRNA_edit PF04073.10 EKE41841.1 - 0.0002 21.2 0.0 0.00042 20.1 0.0 1.6 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain RhoGEF PF00621.15 EKE41842.1 - 8.9e-27 94.1 4.8 1.8e-26 93.1 3.3 1.5 1 0 0 1 1 1 1 RhoGEF domain Mito_fiss_reg PF05308.6 EKE41842.1 - 0.02 14.2 2.2 0.038 13.3 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L32e PF01655.13 EKE41843.1 - 2.1e-43 146.8 0.5 2.5e-43 146.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DUF884 PF05959.6 EKE41843.1 - 0.068 12.4 0.1 0.089 12.0 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) DUF2962 PF11176.3 EKE41844.1 - 6.4e-14 51.7 1.7 7.9e-14 51.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Atg14 PF10186.4 EKE41845.1 - 3.9e-09 35.8 17.4 5.1e-09 35.4 12.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 NYD-SP28_assoc PF14775.1 EKE41845.1 - 3 7.5 11.7 3.5 7.3 1.3 2.9 2 1 0 2 2 2 0 Sperm tail C-terminal domain DNA_topoisoIV PF00521.15 EKE41845.1 - 4.6 5.9 16.5 6.9 5.3 11.4 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF1492 PF07374.6 EKE41845.1 - 4.7 7.3 9.1 0.4 10.7 2.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1492) PNP_UDP_1 PF01048.15 EKE41846.1 - 2.5e-28 98.6 0.0 3.2e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Tic20 PF09685.5 EKE41847.1 - 0.025 14.5 12.5 0.035 14.0 8.7 1.2 1 0 0 1 1 1 0 Tic20-like protein DUF3938 PF13074.1 EKE41847.1 - 0.38 10.6 3.4 0.64 9.8 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) PARP PF00644.15 EKE41848.1 - 1e-57 194.9 0.0 3e-57 193.3 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EKE41848.1 - 4.7e-29 100.7 6.1 9.9e-29 99.6 4.2 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.13 EKE41848.1 - 2.7e-14 53.1 1.3 2.7e-14 53.1 0.9 2.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.7 EKE41848.1 - 1e-11 44.0 0.1 1e-11 44.0 0.1 2.4 3 0 0 3 3 3 1 PADR1 (NUC008) domain WGR PF05406.10 EKE41848.1 - 1.1e-09 38.1 1.0 1.1e-09 38.1 0.7 2.5 3 0 0 3 3 3 1 WGR domain APG9 PF04109.11 EKE41849.1 - 1.8e-07 30.4 4.6 1.8e-07 30.4 3.2 1.6 2 0 0 2 2 2 1 Autophagy protein Apg9 BOFC_N PF08977.5 EKE41849.1 - 0.025 14.3 1.2 0.074 12.8 0.2 2.4 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal Rhodanese PF00581.15 EKE41850.1 - 4.5e-08 33.4 0.0 6.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Viral_P18 PF04521.8 EKE41850.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein SMC_N PF02463.14 EKE41850.1 - 0.15 11.3 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NAP PF00956.13 EKE41851.1 - 3.2e-19 69.0 0.1 3.2e-19 69.0 0.1 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) LRR_5 PF13306.1 EKE41852.1 - 1.1e-08 34.8 30.8 8.6e-08 31.9 7.0 4.2 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) CAP_C PF08603.6 EKE41852.1 - 0.025 13.9 9.8 0.11 11.7 0.1 3.7 1 1 3 4 4 4 0 Adenylate cyclase associated (CAP) C terminal LRR_7 PF13504.1 EKE41852.1 - 3.1 8.4 15.0 43 4.9 0.1 7.9 8 0 0 8 8 8 0 Leucine rich repeat RhoGEF PF00621.15 EKE41853.1 - 1.8e-40 138.7 4.4 3e-40 138.0 1.5 2.0 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EKE41853.1 - 2.1e-16 59.5 8.5 4.3e-16 58.5 5.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE41853.1 - 3e-08 33.8 0.0 5.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 EKE41853.1 - 0.00055 19.8 3.3 0.0017 18.2 2.3 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger E1_DerP2_DerF2 PF02221.10 EKE41854.1 - 1.2e-09 38.4 0.0 1.4e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 ML domain AdoHcyase PF05221.12 EKE41855.1 - 1.5e-128 427.4 0.0 1.8e-128 427.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EKE41855.1 - 5.4e-83 276.7 2.4 8.4e-83 276.0 1.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EKE41855.1 - 6.2e-07 28.7 0.2 1.2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EKE41855.1 - 0.00014 21.3 0.1 0.00027 20.3 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EKE41855.1 - 0.00021 21.2 0.2 0.00057 19.8 0.1 1.8 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EKE41855.1 - 0.0018 18.4 0.3 0.004 17.3 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding TMEM107 PF14995.1 EKE41855.1 - 0.045 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein ELFV_dehydrog PF00208.16 EKE41855.1 - 0.05 13.1 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ras PF00071.17 EKE41856.1 - 1e-40 138.7 0.1 1e-40 138.7 0.1 1.7 1 1 1 2 2 2 1 Ras family Miro PF08477.8 EKE41856.1 - 1.4e-16 61.0 1.7 7.8e-16 58.6 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE41856.1 - 7.7e-10 38.2 0.5 2.7e-09 36.5 0.0 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE41856.1 - 0.001 18.2 1.5 0.0025 16.9 1.1 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE41856.1 - 0.0024 17.8 0.1 0.0072 16.2 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKE41856.1 - 0.42 10.4 5.4 2.6 7.8 3.8 2.2 1 1 0 1 1 1 0 Dynamin family DUF2215 PF10225.4 EKE41856.1 - 0.82 9.0 2.8 1.2 8.5 1.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) SseC PF04888.7 EKE41856.1 - 2.1 7.5 9.2 0.78 9.0 4.6 1.5 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Hom_end_hint PF05203.11 EKE41856.1 - 4.5 6.9 9.0 7 6.3 6.2 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint zf-MIZ PF02891.15 EKE41858.1 - 9.7e-06 25.0 4.3 2e-05 24.0 3.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger LRR_5 PF13306.1 EKE41859.1 - 6.1e-48 161.7 49.1 9e-29 99.7 12.0 7.2 5 3 2 7 7 7 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41859.1 - 1.1e-19 69.9 28.5 7.3e-07 28.8 1.1 6.8 3 1 3 6 6 6 4 Leucine rich repeat MIG-14_Wnt-bd PF06664.7 EKE41860.1 - 2.1e-29 102.2 32.7 2.1e-29 102.2 22.7 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Acetyltransf_1 PF00583.19 EKE41861.1 - 6.1e-10 38.9 0.3 8.7e-10 38.5 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKE41861.1 - 4e-07 29.6 0.0 6.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EKE41861.1 - 6.2e-05 23.0 0.3 8.9e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE41861.1 - 0.0068 16.5 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKE41861.1 - 0.074 12.9 1.0 0.098 12.5 0.7 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hexokinase_2 PF03727.11 EKE41862.1 - 7.1e-41 140.0 0.1 8.2e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Hexokinase RRM_6 PF14259.1 EKE41863.1 - 3.9e-24 84.4 0.3 1.4e-08 34.6 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE41863.1 - 4.3e-23 80.7 3.4 1.1e-06 28.1 0.0 5.1 5 1 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41863.1 - 4.9e-12 45.5 0.0 0.00061 19.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.13 EKE41864.1 - 5.6e-21 75.0 4.0 6.9e-21 74.7 2.8 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SPRY PF00622.23 EKE41865.1 - 0.00058 19.9 0.1 0.00094 19.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain REV PF00424.13 EKE41866.1 - 0.0007 19.4 1.6 0.0007 19.4 1.1 2.5 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) Frag1 PF10277.4 EKE41867.1 - 2.8e-09 36.7 28.5 3.9e-09 36.3 19.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF667 PF05018.8 EKE41869.1 - 0.1 11.7 0.8 0.1 11.8 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF667) Phage_TAC PF06222.6 EKE41870.1 - 0.065 12.7 0.0 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone PIG-P PF08510.7 EKE41871.1 - 1.2e-17 63.6 0.1 1.7e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 PIG-P DUF2207 PF09972.4 EKE41871.1 - 0.0057 15.3 0.1 0.007 15.0 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MutL_C PF08676.6 EKE41872.1 - 5.4e-15 55.2 0.1 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain Herpes_HEPA PF03324.9 EKE41872.1 - 0.0086 16.0 0.2 6.3 6.8 0.0 2.6 2 0 0 2 2 2 2 Herpesvirus DNA helicase/primase complex associated protein DUF3970 PF13113.1 EKE41872.1 - 0.031 13.9 2.9 0.078 12.6 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) HTH_Tnp_1 PF01527.15 EKE41873.1 - 0.078 12.9 2.7 2.8 7.9 0.6 2.4 1 1 1 2 2 2 0 Transposase REGB_T4 PF10715.4 EKE41873.1 - 0.09 12.8 0.6 3.9 7.5 0.0 2.1 1 1 0 2 2 2 0 Endoribonuclease RegB T4-bacteriophage encoded Aminotran_1_2 PF00155.16 EKE41876.1 - 3.1e-37 128.3 0.0 4e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKE41876.1 - 0.0076 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase VSP PF03302.8 EKE41877.1 - 5.5e-07 28.5 41.8 5.5e-07 28.5 29.0 2.0 1 1 1 2 2 2 2 Giardia variant-specific surface protein IF4E PF01652.13 EKE41878.1 - 9.8e-28 96.7 0.2 1.1e-27 96.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_M3_N PF08439.5 EKE41879.1 - 0.3 11.1 5.1 0.18 11.8 0.3 2.8 3 0 0 3 3 3 0 Oligopeptidase F 5-FTHF_cyc-lig PF01812.15 EKE41879.1 - 1.5 8.5 4.9 1.7 8.3 2.8 1.6 1 1 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Dicistro_VP4 PF11492.3 EKE41880.1 - 0.017 15.1 12.4 0.76 9.8 8.2 3.7 1 1 1 2 2 2 0 Cricket paralysis virus, VP4 zf-RING_2 PF13639.1 EKE41881.1 - 1.4e-11 44.0 15.7 1.9e-11 43.6 10.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKE41881.1 - 4.9e-11 42.4 17.3 6.9e-11 41.9 12.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE41881.1 - 7.7e-11 41.5 13.2 1e-10 41.1 9.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE41881.1 - 3.8e-08 32.8 16.0 6.1e-08 32.1 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE41881.1 - 3.7e-06 26.5 14.2 5.8e-06 25.9 9.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EKE41881.1 - 2.9e-05 24.0 14.6 9.6e-05 22.4 10.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 EKE41881.1 - 0.0006 19.0 1.0 0.00073 18.8 0.7 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EKE41881.1 - 0.008 15.8 3.6 0.008 15.8 2.5 2.6 2 2 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EKE41881.1 - 0.0096 15.7 14.5 0.045 13.6 10.3 1.8 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EKE41881.1 - 0.099 12.2 10.4 0.18 11.3 7.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EKE41881.1 - 0.18 11.6 8.2 0.28 11.0 5.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EKE41881.1 - 0.21 11.3 9.1 0.44 10.3 6.3 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EKE41881.1 - 1.7 8.3 17.0 62 3.2 11.9 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EKE41881.1 - 3.1 7.5 10.1 4.8 6.9 7.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.9 EKE41881.1 - 9.9 5.7 11.9 20 4.7 8.3 1.5 1 1 0 1 1 1 0 P-11 zinc finger PAP_assoc PF03828.14 EKE41883.1 - 3.3e-11 42.9 0.1 8.2e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF4445 PF14574.1 EKE41883.1 - 0.12 10.5 0.0 0.21 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) MutS_V PF00488.16 EKE41884.1 - 2.3e-90 302.0 0.1 4.8e-90 301.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EKE41884.1 - 5.1e-28 98.2 4.2 2.2e-27 96.1 2.9 1.9 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EKE41884.1 - 5.2e-09 36.1 7.1 5.2e-09 36.1 4.9 2.7 2 0 0 2 2 2 1 MutS family domain IV F-box-like_2 PF13013.1 EKE41885.1 - 0.21 11.3 1.5 1.5 8.5 0.2 2.8 2 1 1 3 3 3 0 F-box-like domain Presenilin PF01080.12 EKE41885.1 - 1.1 8.0 4.1 1.7 7.3 2.8 1.3 1 0 0 1 1 1 0 Presenilin Ras PF00071.17 EKE41887.1 - 2.5e-55 186.2 0.2 2.9e-55 186.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE41887.1 - 3e-21 75.4 0.0 3.8e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE41887.1 - 7.9e-19 68.3 0.0 1.1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE41887.1 - 1.4e-07 31.1 0.2 1.2e-06 28.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE41887.1 - 2.5e-07 30.0 0.0 3.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE41887.1 - 4.8e-07 29.1 0.0 5.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EKE41887.1 - 2.3e-06 27.1 0.1 5.9e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EKE41887.1 - 1.3e-05 25.1 0.0 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE41887.1 - 7.7e-05 22.8 0.0 0.00077 19.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EKE41887.1 - 0.00066 19.8 0.0 0.0024 18.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKE41887.1 - 0.00081 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase FeoB_N PF02421.13 EKE41887.1 - 0.00094 18.4 0.2 0.0047 16.2 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EKE41887.1 - 0.0016 18.4 0.0 0.034 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EKE41887.1 - 0.0023 17.4 0.2 0.079 12.4 0.2 2.1 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EKE41887.1 - 0.0094 16.7 0.0 0.015 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKE41887.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EKE41887.1 - 0.013 14.2 0.2 3.4 6.2 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 EKE41887.1 - 0.013 14.6 0.0 0.19 10.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EKE41887.1 - 0.015 14.8 0.2 3.6 7.0 0.0 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EKE41887.1 - 0.016 14.6 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EKE41887.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 EKE41887.1 - 0.025 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_15 PF13175.1 EKE41887.1 - 0.029 13.4 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EKE41887.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EKE41887.1 - 0.041 14.0 0.1 0.085 13.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EKE41887.1 - 0.043 14.1 0.0 0.064 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 EKE41887.1 - 0.066 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_25 PF13481.1 EKE41887.1 - 0.15 11.4 0.2 0.83 9.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain C1_1 PF00130.17 EKE41888.1 - 3.2 7.5 19.4 0.18 11.5 3.2 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2797 PF10977.3 EKE41888.1 - 5.2 6.6 7.3 9.3 5.7 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) PRELI PF04707.9 EKE41889.1 - 1.5e-10 40.9 0.1 3.3e-10 39.7 0.1 1.6 1 1 1 2 2 2 1 PRELI-like family PfkB PF00294.19 EKE41891.1 - 2.2e-48 164.9 0.7 2.8e-48 164.6 0.5 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF89 PF01937.14 EKE41891.1 - 0.048 12.4 0.1 0.1 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF89 PP2C PF00481.16 EKE41893.1 - 3.8e-53 180.4 0.0 6.4e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE41893.1 - 0.00033 20.1 0.0 0.00068 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C UPF0147 PF03685.8 EKE41893.1 - 0.055 13.3 1.5 1.2 9.0 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) Pkinase PF00069.20 EKE41895.1 - 3.5e-68 229.5 0.0 4.2e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41895.1 - 1.3e-33 116.2 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EKE41895.1 - 2.2e-20 72.4 0.0 1.7e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 EKE41895.1 - 2.4e-06 26.7 0.0 4.7e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EKE41895.1 - 2.9e-05 23.2 0.0 4.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE41895.1 - 0.0011 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKE41895.1 - 0.096 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EKE41895.1 - 0.18 11.1 0.6 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Brix PF04427.13 EKE41899.1 - 1.3e-34 119.5 0.2 1.8e-34 119.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain GBP PF02263.14 EKE41900.1 - 7.7e-26 90.6 1.0 1.3e-25 89.9 0.7 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EKE41900.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase TSGA13 PF14994.1 EKE41900.1 - 0.012 14.7 0.8 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 Testis-specific gene 13 protein AAA_14 PF13173.1 EKE41900.1 - 0.06 13.2 0.1 0.06 13.2 0.1 2.9 3 2 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EKE41900.1 - 0.21 11.7 2.7 6.7 6.9 0.0 3.8 4 1 0 4 4 4 0 RNA helicase HD_3 PF13023.1 EKE41901.1 - 8.2e-42 142.7 0.0 9.8e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EKE41901.1 - 0.00048 20.1 0.1 0.00072 19.5 0.1 1.4 1 1 0 1 1 1 1 HD domain Phage_HK97_TLTM PF06120.6 EKE41902.1 - 0.021 14.1 4.4 0.028 13.7 3.0 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Toxin_10 PF05431.6 EKE41902.1 - 0.11 12.0 6.8 0.07 12.7 3.2 1.7 1 1 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DNA_pol_B PF00136.16 EKE41902.1 - 0.2 10.3 6.4 0.25 10.0 4.3 1.2 1 1 0 1 1 1 0 DNA polymerase family B Peptidase_C65 PF10275.4 EKE41902.1 - 0.48 9.7 12.6 1.3 8.2 3.9 2.9 1 1 1 2 2 2 0 Peptidase C65 Otubain DUF2935 PF11155.3 EKE41902.1 - 0.54 10.3 5.2 3.9 7.5 3.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF445 PF04286.7 EKE41902.1 - 2.9 7.3 12.7 7.8 5.9 8.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF3870 PF12986.2 EKE41902.1 - 6.4 7.0 13.6 2 8.7 0.5 3.6 1 1 2 4 4 4 0 Domain of unknown function (DUF3870) YbaJ PF10757.4 EKE41902.1 - 6.8 6.8 8.2 0.87 9.7 0.6 2.8 1 1 1 2 2 2 0 Biofilm formation regulator YbaJ tRNA-synt_2 PF00152.15 EKE41903.1 - 6.9e-80 268.3 0.2 6.9e-80 268.3 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKE41903.1 - 1.1e-06 28.3 0.9 2.2e-06 27.4 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EKE41903.1 - 4.4e-05 22.8 0.9 0.013 14.6 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) DUF4366 PF14283.1 EKE41905.1 - 0.033 13.6 0.3 0.033 13.6 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) LMBR1 PF04791.11 EKE41905.1 - 0.11 11.0 8.1 0.051 12.1 2.8 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein YjgP_YjgQ PF03739.9 EKE41905.1 - 0.23 10.1 3.2 0.2 10.3 0.5 1.9 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family TMEM154 PF15102.1 EKE41905.1 - 0.31 10.7 9.3 0.14 11.9 4.2 2.0 1 1 1 2 2 2 0 TMEM154 protein family Prion PF00377.13 EKE41905.1 - 1.9 8.2 9.7 0.19 11.4 0.4 3.0 3 0 0 3 3 3 0 Prion/Doppel alpha-helical domain DUF2207 PF09972.4 EKE41905.1 - 9.2 4.7 14.5 0.087 11.3 3.7 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) YjeF_N PF03853.10 EKE41906.1 - 1.4e-41 141.9 0.0 1.7e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus UEV PF05743.8 EKE41907.1 - 0.01 15.5 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 0 UEV domain DUF2120 PF09893.4 EKE41907.1 - 0.22 11.4 1.5 3.4 7.5 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) PQ-loop PF04193.9 EKE41908.1 - 9.1e-15 53.9 0.8 9.1e-15 53.9 0.6 3.1 4 0 0 4 4 4 2 PQ loop repeat SieB PF14163.1 EKE41908.1 - 2 7.9 8.5 4.7 6.7 5.9 1.6 1 0 0 1 1 1 0 Superinfection exclusion protein B Rft-1 PF04506.8 EKE41909.1 - 2.9e-48 164.6 45.8 6e-39 133.8 18.8 2.1 1 1 1 2 2 2 2 Rft protein MadM PF03818.8 EKE41909.1 - 0.42 10.2 7.6 0.43 10.1 0.1 4.1 4 0 0 4 4 4 0 Malonate/sodium symporter MadM subunit DOCK-C2 PF14429.1 EKE41910.1 - 5.6e-41 140.1 4.7 5.6e-41 140.1 3.2 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EKE41910.1 - 4.1e-27 94.6 0.1 4.1e-27 94.6 0.1 3.3 2 1 1 3 3 3 1 Dedicator of cytokinesis EF-hand_6 PF13405.1 EKE41910.1 - 0.019 14.8 0.1 0.21 11.5 0.1 2.9 1 0 0 1 1 1 0 EF-hand domain Rotamase PF00639.16 EKE41910.1 - 0.49 11.1 7.8 1.4 9.7 1.2 3.7 3 1 1 4 4 4 0 PPIC-type PPIASE domain SpecificRecomb PF10136.4 EKE41910.1 - 1.3 6.9 1.0 2.2 6.2 0.7 1.2 1 0 0 1 1 1 0 Site-specific recombinase Pkinase_Tyr PF07714.12 EKE41911.1 - 1.1e-46 159.0 0.0 2.8e-46 157.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41911.1 - 2.3e-44 151.5 0.0 7.8e-44 149.7 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.1 EKE41911.1 - 8.1e-12 44.7 33.8 1.5e-05 24.6 0.5 6.1 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EKE41911.1 - 1.4e-10 40.5 42.8 5.6e-06 25.8 3.9 7.5 4 2 3 8 8 8 4 Leucine Rich repeats (2 copies) Myotub-related PF06602.9 EKE41911.1 - 9.1e-10 37.8 0.6 2e-09 36.7 0.4 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain LRR_1 PF00560.28 EKE41911.1 - 0.00097 18.8 29.3 4.8 7.6 0.4 9.7 9 1 0 9 9 9 2 Leucine Rich Repeat Kdo PF06293.9 EKE41911.1 - 0.021 13.9 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE41911.1 - 0.12 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_7 PF13504.1 EKE41911.1 - 1.9 9.0 18.0 71 4.2 0.6 8.8 10 0 0 10 10 10 0 Leucine rich repeat Radical_SAM PF04055.16 EKE41912.1 - 1.3e-22 80.6 2.3 2e-22 80.1 1.6 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 EKE41912.1 - 8e-12 44.8 1.3 8e-12 44.8 0.9 2.0 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 EKE41912.1 - 0.067 12.9 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 TRAM domain EF-hand_8 PF13833.1 EKE41913.1 - 6.9e-05 22.3 0.1 6.9e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EKE41913.1 - 0.0019 17.3 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 EF hand AAA PF00004.24 EKE41914.1 - 2.7e-42 144.1 0.0 4.8e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE41914.1 - 1e-07 32.1 0.1 2e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKE41914.1 - 2.6e-07 30.8 0.5 0.00048 20.2 0.0 2.8 2 1 1 3 3 2 2 AAA domain AAA_2 PF07724.9 EKE41914.1 - 3.5e-07 30.3 0.0 2.2e-06 27.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EKE41914.1 - 4e-07 29.8 0.2 1.1e-05 25.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EKE41914.1 - 8.3e-06 26.6 0.2 2.4e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EKE41914.1 - 8.6e-06 24.9 0.0 1.7e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EKE41914.1 - 0.00019 21.7 0.4 0.00054 20.2 0.0 2.2 2 1 1 3 3 1 1 AAA domain RNA_helicase PF00910.17 EKE41914.1 - 0.00034 20.7 0.0 0.001 19.2 0.0 1.9 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 EKE41914.1 - 0.00052 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EKE41914.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EKE41914.1 - 0.00086 18.2 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EKE41914.1 - 0.0011 17.7 1.3 0.0026 16.5 0.0 2.2 3 0 0 3 3 3 1 TIP49 C-terminus AAA_19 PF13245.1 EKE41914.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EKE41914.1 - 0.0019 17.4 0.1 0.0052 15.9 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EKE41914.1 - 0.0038 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EKE41914.1 - 0.0039 16.5 0.4 0.061 12.7 0.1 2.2 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKE41914.1 - 0.0045 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EKE41914.1 - 0.0072 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EKE41914.1 - 0.0093 16.0 0.0 0.046 13.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.7 EKE41914.1 - 0.0097 15.5 0.0 0.043 13.4 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 EKE41914.1 - 0.0098 15.5 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sec8_exocyst PF04048.9 EKE41914.1 - 0.013 15.1 1.7 0.035 13.7 1.2 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain AAA_11 PF13086.1 EKE41914.1 - 0.014 15.0 0.1 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EKE41914.1 - 0.018 13.9 0.0 0.049 12.5 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EKE41914.1 - 0.02 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 EKE41914.1 - 0.027 13.9 0.1 0.14 11.6 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EKE41914.1 - 0.029 14.0 0.2 0.29 10.8 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase AAA_26 PF13500.1 EKE41914.1 - 0.029 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EKE41914.1 - 0.034 13.3 0.0 0.091 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 EKE41914.1 - 0.034 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EKE41914.1 - 0.045 12.8 0.9 0.29 10.1 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 EKE41914.1 - 0.054 13.8 2.5 11 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 EKE41914.1 - 0.069 12.9 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KTI12 PF08433.5 EKE41914.1 - 0.095 11.8 0.5 0.58 9.3 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EKE41914.1 - 0.1 12.8 0.1 0.42 10.8 0.0 2.1 2 1 1 3 3 2 0 ABC transporter DUF1366 PF07104.6 EKE41914.1 - 0.13 11.8 2.9 0.22 11.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Abi PF02517.11 EKE41915.1 - 1.7e-10 40.8 2.4 1.7e-10 40.8 1.7 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity DUF1241 PF06840.6 EKE41915.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) PerB PF06590.6 EKE41915.1 - 0.67 10.2 5.6 0.29 11.4 1.4 2.2 1 1 2 3 3 3 0 PerB protein SNARE PF05739.14 EKE41916.1 - 3.9e-10 39.2 6.9 3.9e-10 39.2 4.8 2.3 3 0 0 3 3 3 1 SNARE domain Tropomyosin_1 PF12718.2 EKE41916.1 - 0.00018 21.3 22.2 0.0037 17.1 6.0 2.4 2 1 0 2 2 2 2 Tropomyosin like SseC PF04888.7 EKE41916.1 - 0.01 15.1 1.3 0.01 15.1 0.9 3.2 2 1 1 3 3 3 0 Secretion system effector C (SseC) like family DUF3753 PF12575.3 EKE41916.1 - 0.012 15.3 1.0 0.04 13.7 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Sarcoglycan_2 PF05510.8 EKE41916.1 - 0.019 13.3 0.1 0.019 13.3 0.1 1.7 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Striatin PF08232.7 EKE41916.1 - 0.048 13.9 11.1 0.42 10.9 1.5 2.1 2 0 0 2 2 2 0 Striatin family DUF4191 PF13829.1 EKE41916.1 - 0.071 12.2 0.1 0.071 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Tweety PF04906.8 EKE41916.1 - 0.087 11.2 10.4 0.28 9.5 1.6 2.0 2 0 0 2 2 2 0 Tweety DASH_Dad3 PF08656.5 EKE41916.1 - 0.16 11.6 0.2 0.16 11.6 0.2 3.5 2 2 1 3 3 3 0 DASH complex subunit Dad3 DUF912 PF06024.7 EKE41916.1 - 0.32 11.0 12.0 0.024 14.6 2.6 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tropomyosin PF00261.15 EKE41916.1 - 0.33 10.0 14.8 0.21 10.6 1.4 2.3 2 0 0 2 2 2 0 Tropomyosin DASH_Dam1 PF08653.5 EKE41916.1 - 0.78 9.5 3.5 6.2 6.6 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF3169 PF11368.3 EKE41916.1 - 1 8.5 8.6 0.16 11.1 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Fzo_mitofusin PF04799.8 EKE41916.1 - 1.2 8.5 16.0 0.029 13.7 2.9 2.4 2 1 0 2 2 2 0 fzo-like conserved region Renin_r PF07850.9 EKE41916.1 - 1.2 9.5 3.7 2.2 8.6 0.3 2.3 2 1 0 2 2 2 0 Renin receptor-like protein Rhabdo_glycop PF00974.13 EKE41916.1 - 1.2 7.2 5.2 1.4 7.0 0.8 2.0 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein ETRAMP PF09716.5 EKE41916.1 - 1.7 8.6 12.6 0.042 13.7 2.6 2.6 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CaMBD PF02888.11 EKE41916.1 - 1.7 8.4 5.8 0.35 10.7 0.5 2.3 3 0 0 3 3 3 0 Calmodulin binding domain FliD_N PF02465.13 EKE41916.1 - 1.8 8.9 9.9 0.15 12.4 0.9 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SUKH_6 PF14568.1 EKE41916.1 - 2.2 8.7 9.5 1.6 9.2 0.2 2.8 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall Laminin_II PF06009.7 EKE41916.1 - 2.8 7.7 14.4 3.8 7.2 1.7 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF3450 PF11932.3 EKE41916.1 - 8.7 5.5 18.2 6.1 6.0 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 EKE41916.1 - 9.6 6.0 13.2 2.2 8.0 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1900 PF08954.6 EKE41917.1 - 2.9e-67 224.3 0.8 9.9e-34 115.7 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1900) WD40 PF00400.27 EKE41917.1 - 8e-21 73.0 11.8 5.3e-05 22.9 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF1899 PF08953.6 EKE41917.1 - 1.9e-18 65.8 0.1 8.3e-09 34.9 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) Ras PF00071.17 EKE41918.1 - 6.3e-54 181.7 0.1 7.3e-54 181.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41918.1 - 1.1e-21 77.5 0.0 1.6e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41918.1 - 1.8e-12 46.8 0.0 2.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41918.1 - 7.1e-08 32.1 0.0 3.2e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE41918.1 - 1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE41918.1 - 2.1e-05 23.8 0.0 2.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EKE41918.1 - 2.2e-05 23.9 0.0 0.16 11.4 0.0 2.3 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EKE41918.1 - 0.0001 21.5 0.0 0.00018 20.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKE41918.1 - 0.00039 20.5 0.0 0.00066 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EKE41918.1 - 0.018 14.4 0.1 0.11 11.9 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EKE41918.1 - 0.019 14.6 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EKE41918.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EKE41918.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EKE41918.1 - 0.038 13.2 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EKE41918.1 - 0.044 12.8 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 EKE41918.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EKE41918.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EKE41918.1 - 0.055 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EKE41918.1 - 0.055 13.6 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EKE41918.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EKE41918.1 - 0.13 11.1 0.0 0.8 8.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF815) SLBP_RNA_bind PF15247.1 EKE41919.1 - 6e-30 102.8 1.6 1.2e-29 101.8 0.7 1.8 1 1 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain TK PF00265.13 EKE41920.1 - 0.00043 19.8 0.7 0.00071 19.1 0.5 1.3 1 0 0 1 1 1 1 Thymidine kinase Pkinase_Tyr PF07714.12 EKE41921.1 - 1.5e-54 184.7 0.1 1.9e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41921.1 - 1.1e-52 178.7 0.1 1.6e-52 178.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.6 EKE41921.1 - 0.0035 16.2 0.1 0.0066 15.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EKE41921.1 - 0.0039 16.2 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKE41921.1 - 0.0061 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myotub-related PF06602.9 EKE41922.1 - 2.2e-98 329.2 0.3 4.3e-98 328.3 0.0 1.6 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain GRAM PF02893.15 EKE41922.1 - 0.00015 21.2 0.1 0.0004 19.8 0.1 1.8 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.1 EKE41922.1 - 0.015 15.5 0.1 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF1448 PF07289.6 EKE41922.1 - 0.022 13.7 0.3 0.04 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) bPH_5 PF10882.3 EKE41922.1 - 0.058 13.1 0.1 0.67 9.7 0.0 2.4 1 1 1 2 2 2 0 Bacterial PH domain PH PF00169.24 EKE41922.1 - 0.18 12.0 3.3 0.24 11.6 0.1 2.4 2 0 0 2 2 2 0 PH domain POR_N PF01855.14 EKE41923.1 - 5.6e-79 264.8 0.0 8.6e-79 264.2 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 EKE41923.1 - 1.1e-24 87.2 0.1 1.9e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.4 EKE41923.1 - 9.6e-22 76.3 0.2 4e-21 74.3 0.1 2.1 2 0 0 2 2 1 1 Domain of unknown function TPP_enzyme_C PF02775.16 EKE41923.1 - 8e-09 35.2 0.1 2.6e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_9 PF13187.1 EKE41923.1 - 4.2e-07 30.1 9.5 0.00071 19.7 2.2 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EKE41923.1 - 1.3e-06 28.1 14.1 1.3e-06 28.1 9.8 2.7 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EKE41923.1 - 1.3e-06 28.6 14.4 1.3e-06 28.6 10.0 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4 PF00037.22 EKE41923.1 - 2.7e-06 26.7 20.5 9.6e-05 21.8 0.5 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EKE41923.1 - 5.9e-06 26.2 12.9 1.7e-05 24.7 8.9 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKE41923.1 - 1.5e-05 24.6 15.2 0.00068 19.3 1.2 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 EKE41923.1 - 9e-05 23.1 10.5 9e-05 23.1 7.2 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 EKE41923.1 - 0.0001 22.5 12.0 0.00071 19.8 8.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKE41923.1 - 0.00043 20.0 17.3 0.00076 19.2 9.8 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKE41923.1 - 0.0022 17.8 18.8 0.0048 16.7 1.8 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EKE41923.1 - 0.03 14.7 14.4 1.1 9.7 4.0 3.2 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 EKE41923.1 - 0.58 10.6 18.1 1.2 9.6 3.9 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain LRR_5 PF13306.1 EKE41924.1 - 2.7e-113 373.0 66.3 2.9e-33 114.2 6.4 5.1 1 1 4 5 5 5 5 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE41924.1 - 7.9e-31 105.6 35.0 5.1e-07 29.3 0.3 9.2 3 3 7 10 10 10 10 Leucine rich repeat hDGE_amylase PF14701.1 EKE41925.1 - 2.1e-124 415.6 1.5 2.1e-124 415.6 1.1 1.7 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EKE41925.1 - 9.8e-98 327.2 0.5 1.6e-97 326.5 0.1 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EKE41925.1 - 9.3e-40 136.4 2.1 9.3e-40 136.4 1.4 2.4 2 1 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EKE41925.1 - 4.9e-10 39.1 2.4 1.3e-09 37.7 1.7 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Cnd2 PF05786.9 EKE41926.1 - 2.8e-27 95.5 3.6 2.8e-27 95.5 2.5 3.1 2 1 0 2 2 2 1 Condensin complex subunit 2 CYTH PF01928.16 EKE41927.1 - 6.2e-12 45.5 0.7 8.2e-12 45.1 0.5 1.1 1 0 0 1 1 1 1 CYTH domain Pep_M12B_propep PF01562.14 EKE41927.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide CH PF00307.26 EKE41928.1 - 9.1e-12 44.9 0.1 1.5e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.17 EKE41928.1 - 2.4e-06 27.5 7.6 4.4e-06 26.6 5.3 1.5 1 0 0 1 1 1 1 LIM domain CAMSAP_CH PF11971.3 EKE41928.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain Prok-RING_1 PF14446.1 EKE41928.1 - 0.53 10.0 8.1 0.31 10.7 2.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 EKE41928.1 - 0.54 10.1 8.8 11 5.8 6.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EKE41928.1 - 1.1 9.0 6.2 8.8 6.1 2.2 2.6 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NOB1_Zn_bind PF08772.6 EKE41928.1 - 1.8 8.4 9.1 2.8 7.8 2.3 2.6 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF607 PF04678.8 EKE41928.1 - 2.3 8.1 8.7 8.4 6.2 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 YPEB PF14620.1 EKE41928.1 - 2.6 6.9 15.1 0.51 9.3 0.2 2.3 2 0 0 2 2 2 0 YpeB sporulation U79_P34 PF03064.11 EKE41928.1 - 4.7 6.6 21.7 0.25 10.8 1.5 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 GPCR_chapero_1 PF11904.3 EKE41929.1 - 1.6e-20 73.4 3.4 3.1e-13 49.5 0.1 2.1 1 1 1 2 2 2 2 GPCR-chaperone Ank_4 PF13637.1 EKE41929.1 - 6e-12 45.7 1.1 8.7e-08 32.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE41929.1 - 1e-08 35.4 0.0 1.3e-06 28.6 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE41929.1 - 3.7e-08 33.3 0.6 1.8e-05 24.8 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EKE41929.1 - 1.4e-07 30.9 0.0 0.00013 21.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EKE41929.1 - 1.8e-05 24.5 0.1 0.0068 16.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat DUF4412 PF14371.1 EKE41929.1 - 0.011 16.1 0.0 0.23 11.9 0.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4412) Sel1 PF08238.7 EKE41930.1 - 6.9e-57 188.6 15.6 8.9e-08 32.5 0.0 13.1 14 0 0 14 14 14 8 Sel1 repeat Pkinase PF00069.20 EKE41930.1 - 9.4e-42 142.9 0.1 2.5e-41 141.5 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41930.1 - 1e-30 106.6 0.0 2.3e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_6 PF13174.1 EKE41930.1 - 1.6e-06 28.1 7.6 5.2 7.7 0.1 9.1 8 2 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41930.1 - 4.7e-06 27.1 0.9 1.3 9.7 0.0 6.3 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKE41930.1 - 0.0028 17.2 23.6 2.2 8.0 0.6 7.2 6 1 1 8 8 8 2 TPR repeat TPR_12 PF13424.1 EKE41930.1 - 0.15 12.0 4.8 0.71 9.8 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKE41930.1 - 4.3 7.7 16.4 12 6.4 0.1 7.2 7 3 2 10 10 10 0 Tetratricopeptide repeat Med14 PF08638.6 EKE41931.1 - 0.0034 16.6 0.2 0.025 13.8 0.0 2.5 3 0 0 3 3 3 1 Mediator complex subunit MED14 EF-hand_5 PF13202.1 EKE41932.1 - 0.072 12.4 0.2 0.22 10.9 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 EKE41932.1 - 0.089 12.1 1.4 0.26 10.6 1.0 1.8 1 0 0 1 1 1 0 EF hand DUF2019 PF09450.5 EKE41932.1 - 0.12 12.2 0.1 0.43 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) DUF4602 PF15375.1 EKE41932.1 - 1.9 8.5 27.1 0.032 14.3 11.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) NBP1 PF08537.5 EKE41933.1 - 0.013 14.7 1.3 0.029 13.5 0.3 1.7 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 Smr PF01713.16 EKE41935.1 - 6.9e-09 35.7 0.0 3.7e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 EKE41935.1 - 0.00018 20.8 2.6 0.0035 16.7 0.1 2.7 2 0 0 2 2 2 1 CUE domain DUF2018 PF09442.5 EKE41935.1 - 0.17 12.4 0.2 0.17 12.4 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) Pkinase PF00069.20 EKE41936.1 - 1e-48 165.7 0.3 2e-48 164.8 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41936.1 - 1.4e-48 165.2 0.1 2.2e-48 164.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.8 EKE41936.1 - 0.45 9.0 132.8 0.004 15.8 14.1 5.2 1 1 4 5 5 5 0 Giardia variant-specific surface protein ubiquitin PF00240.18 EKE41937.1 - 2e-07 30.2 0.1 2.5e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE41937.1 - 3.5e-06 26.6 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FERM_N PF09379.5 EKE41937.1 - 0.047 13.7 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 FERM N-terminal domain TUG-UBL1 PF11470.3 EKE41937.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PAP2 PF01569.16 EKE41938.1 - 4.6e-11 42.5 4.7 4.6e-11 42.5 3.3 3.0 2 2 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EKE41938.1 - 3.6e-07 29.9 0.3 3.6e-07 29.9 0.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EKE41938.1 - 0.0022 18.2 4.2 0.0022 18.2 2.9 4.0 4 1 1 5 5 5 1 PAP2 superfamily C-terminal Pkinase_Tyr PF07714.12 EKE41939.1 - 1.2e-53 181.7 0.1 2e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE41939.1 - 1.4e-51 175.1 0.0 2.6e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Motile_Sperm PF00635.21 EKE41939.1 - 0.06 12.9 0.9 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 MSP (Major sperm protein) domain Kinase-like PF14531.1 EKE41939.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EKE41939.1 - 0.25 10.3 0.0 0.43 9.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VSP PF03302.8 EKE41939.1 - 3.6 6.1 150.2 67 1.9 57.8 6.4 1 1 1 2 2 2 0 Giardia variant-specific surface protein FHIPEP PF00771.15 EKE41940.1 - 0.55 8.4 3.3 0.76 8.0 2.3 1.1 1 0 0 1 1 1 0 FHIPEP family IU_nuc_hydro PF01156.14 EKE41941.1 - 5.2e-48 163.8 0.1 2.4e-38 132.1 0.0 2.0 1 1 1 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase MOZART2 PF12926.2 EKE41942.1 - 0.013 15.1 0.1 0.081 12.5 0.1 2.4 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated HEAT PF02985.17 EKE41943.1 - 1.4e-25 87.0 9.0 0.00011 21.9 0.0 11.5 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.1 EKE41943.1 - 7.7e-24 83.7 3.5 1e-06 28.9 0.1 7.5 7 1 0 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EKE41943.1 - 5.4e-18 64.9 13.9 3.4e-05 24.1 0.0 10.2 12 1 2 14 14 14 5 HEAT-like repeat CLASP_N PF12348.3 EKE41943.1 - 1.4e-10 40.9 1.6 0.0011 18.3 0.1 6.3 4 1 2 6 6 6 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 EKE41943.1 - 5.2e-10 39.5 0.3 0.0034 17.7 0.0 6.7 5 1 0 5 5 5 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EKE41943.1 - 8.8e-07 28.5 6.2 0.7 9.8 0.1 7.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DUF3535 PF12054.3 EKE41943.1 - 2.4e-05 23.1 0.1 0.04 12.5 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3535) Vps26 PF03643.10 EKE41944.1 - 0.00049 18.9 0.0 0.0007 18.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Peptidase_S64 PF08192.6 EKE41944.1 - 0.017 13.4 1.5 0.021 13.2 1.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 CagX PF03524.10 EKE41944.1 - 0.039 13.2 0.2 0.045 13.0 0.1 1.1 1 0 0 1 1 1 0 Conjugal transfer protein WD40 PF00400.27 EKE41945.1 - 7.5e-08 31.9 3.7 0.0018 18.0 0.2 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE41945.1 - 2.1e-05 24.2 0.3 0.031 14.0 0.0 3.2 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 EKE41945.1 - 0.039 14.2 0.0 0.19 12.0 0.0 2.1 1 1 1 2 2 2 0 HEAT repeats PK PF00224.16 EKE41946.1 - 6.9e-12 44.6 0.2 7.8e-12 44.4 0.2 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain ThiF PF00899.16 EKE41947.1 - 3.6e-39 133.6 0.7 1.9e-30 105.4 0.1 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EKE41947.1 - 1e-24 85.8 2.3 4.9e-18 64.4 0.2 3.2 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EKE41947.1 - 7.6e-22 76.4 3.3 1.9e-18 65.5 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site Spatacsin_C PF14649.1 EKE41948.1 - 9.3e-16 57.5 1.5 3.4e-15 55.6 1.0 2.0 1 0 0 1 1 1 1 Spatacsin C-terminus DNA_pol3_gamma3 PF12169.3 EKE41948.1 - 0.21 11.3 4.2 3.8 7.2 0.0 3.2 4 0 0 4 4 4 0 DNA polymerase III subunits gamma and tau domain III DUF3283 PF11686.3 EKE41949.1 - 0.088 12.6 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3283) DNA_ligase_A_M PF01068.16 EKE41951.1 - 6.4e-60 201.9 1.1 1.4e-59 200.9 0.7 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EKE41951.1 - 2.7e-33 115.2 0.0 5.9e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EKE41951.1 - 2.1e-27 95.3 0.0 2e-26 92.2 0.0 2.6 3 1 1 4 4 4 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EKE41951.1 - 0.00085 19.0 0.7 0.23 11.1 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 EKE41951.1 - 0.012 15.2 0.6 0.11 12.1 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain DUF3276 PF11680.3 EKE41951.1 - 0.014 15.1 0.4 0.014 15.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) DUF4325 PF14213.1 EKE41951.1 - 0.019 14.6 0.0 0.056 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) Actin PF00022.14 EKE41952.1 - 1.6e-109 365.9 0.0 2e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKE41952.1 - 0.00018 20.2 0.0 0.19 10.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein UPF0546 PF10639.4 EKE41953.1 - 2.6e-33 114.1 5.5 2.6e-33 114.1 3.8 1.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EKE41953.1 - 0.52 10.3 15.4 0.38 10.7 6.2 2.7 1 1 2 3 3 3 0 EamA-like transporter family DUF2062 PF09835.4 EKE41953.1 - 6.6 6.3 7.3 1.6 8.3 0.7 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) EmrE PF13536.1 EKE41953.1 - 8.1 6.6 13.9 82 3.4 9.7 2.3 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Pkinase PF00069.20 EKE41954.1 - 4.1e-11 42.5 0.2 9e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41954.1 - 6.7e-06 25.3 0.0 1.7e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EKE41954.1 - 0.051 13.7 0.5 0.27 11.4 0.3 2.2 1 1 0 1 1 1 0 PH domain DUF4570 PF15134.1 EKE41954.1 - 0.1 12.4 0.2 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) SlyX PF04102.7 EKE41954.1 - 0.14 12.5 3.2 0.28 11.5 2.2 1.5 1 0 0 1 1 1 0 SlyX DUF2730 PF10805.3 EKE41954.1 - 0.65 9.7 6.9 0.048 13.3 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) RRP7 PF12923.2 EKE41955.1 - 2.4e-08 34.0 12.0 3e-08 33.7 8.3 1.0 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) OSR1_C PF12202.3 EKE41955.1 - 0.011 15.2 3.2 0.19 11.3 0.1 2.7 2 1 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C terminal Occludin_ELL PF07303.8 EKE41955.1 - 5.4 7.8 13.7 0.58 10.9 4.5 2.1 2 0 0 2 2 2 0 Occludin homology domain Y_phosphatase3 PF13350.1 EKE41956.1 - 8e-07 29.4 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EKE41956.1 - 1.2e-05 24.9 0.3 3.6e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE41956.1 - 2.3e-05 23.8 0.3 4.3e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTEN_C2 PF10409.4 EKE41956.1 - 0.00014 21.5 0.3 0.0003 20.5 0.2 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.1 EKE41956.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 EKE41956.1 - 0.02 14.3 0.0 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 EKE41956.1 - 0.05 12.9 1.4 0.064 12.6 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family UBX PF00789.15 EKE41957.1 - 6.2e-09 35.8 0.0 1.7e-08 34.4 0.0 1.8 1 1 1 2 2 2 1 UBX domain PIF1 PF05970.9 EKE41958.1 - 5.5e-56 190.0 6.6 7.7e-45 153.4 0.2 3.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EKE41958.1 - 1.1e-15 57.7 0.0 1.9e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EKE41958.1 - 4.3e-09 34.7 0.2 0.00035 18.4 0.1 2.3 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.1 EKE41958.1 - 3.8e-07 30.3 0.0 1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKE41958.1 - 4.5e-05 23.6 0.1 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EKE41958.1 - 0.00013 21.5 0.4 0.014 14.9 0.2 3.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EKE41958.1 - 0.00042 20.2 0.0 0.0033 17.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKE41958.1 - 0.00051 19.7 0.0 0.00095 18.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EKE41958.1 - 0.0012 18.8 0.1 0.0049 16.8 0.0 1.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EKE41958.1 - 0.002 17.8 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.9 EKE41958.1 - 0.0027 17.3 0.1 0.01 15.4 0.0 2.0 1 1 0 1 1 1 1 Helicase Arch_ATPase PF01637.13 EKE41958.1 - 0.0028 17.4 0.2 0.012 15.2 0.1 2.1 1 1 0 1 1 1 1 Archaeal ATPase UvrD_C_2 PF13538.1 EKE41958.1 - 0.0077 16.3 0.0 0.031 14.3 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 EKE41958.1 - 0.009 14.9 0.1 0.021 13.7 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EKE41958.1 - 0.018 14.5 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 EKE41958.1 - 0.019 14.1 0.1 0.17 11.0 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein AFG1_ATPase PF03969.11 EKE41958.1 - 0.037 12.8 0.0 0.071 11.8 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase DEAD PF00270.24 EKE41958.1 - 0.054 12.9 0.1 7.7 5.9 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_29 PF13555.1 EKE41958.1 - 0.07 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EKE41958.1 - 0.081 12.3 0.3 11 5.3 0.1 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EKE41958.1 - 0.086 13.6 1.3 0.25 12.1 0.0 2.5 3 1 0 3 3 2 0 AAA domain La PF05383.12 EKE41959.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 La domain Mpp10 PF04006.7 EKE41960.1 - 2e-50 171.7 48.3 1.6e-47 162.2 20.0 2.0 1 1 1 2 2 2 2 Mpp10 protein RhoGEF PF00621.15 EKE41961.1 - 1.1e-32 113.4 13.2 1.1e-32 113.4 9.2 3.0 3 0 0 3 3 3 1 RhoGEF domain DUF59 PF01883.14 EKE41963.1 - 4.6e-06 26.5 0.4 7.7e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 RhoGAP PF00620.22 EKE41965.1 - 6.6e-23 80.9 1.1 1.2e-22 80.1 0.2 1.8 2 0 0 2 2 2 1 RhoGAP domain Seryl_tRNA_N PF02403.17 EKE41965.1 - 0.013 15.5 3.2 0.86 9.6 0.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF997 PF06196.7 EKE41966.1 - 0.023 14.1 0.7 0.037 13.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF1700 PF08006.6 EKE41966.1 - 0.025 13.8 2.5 0.027 13.7 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) DUF912 PF06024.7 EKE41966.1 - 0.91 9.6 7.5 0.11 12.5 1.7 2.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 EKE41966.1 - 3.9 7.3 7.7 1.4 8.7 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) FH2 PF02181.18 EKE41967.1 - 9.3e-85 284.7 6.7 9.3e-85 284.7 4.6 3.4 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EKE41967.1 - 2e-09 37.1 5.9 7.4e-09 35.2 4.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EKE41967.1 - 2.3e-05 23.8 2.6 2.3e-05 23.8 1.8 2.9 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Prok-RING_1 PF14446.1 EKE41967.1 - 7.3e-05 22.4 4.2 0.00016 21.3 2.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 EKE41967.1 - 0.00076 19.1 3.1 0.0016 18.1 2.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Drf_FH1 PF06346.7 EKE41967.1 - 0.005 16.3 46.4 0.0081 15.6 32.2 1.2 1 0 0 1 1 1 1 Formin Homology Region 1 zf-RING_2 PF13639.1 EKE41967.1 - 0.069 12.9 3.7 0.14 11.9 2.6 1.5 1 0 0 1 1 1 0 Ring finger domain DNA_RNApol_7kD PF03604.8 EKE41967.1 - 0.074 12.5 2.8 0.2 11.1 1.9 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Tnp_zf-ribbon_2 PF13842.1 EKE41967.1 - 2 8.8 5.8 5.3 7.5 4.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon PP2C PF00481.16 EKE41968.1 - 5.8e-52 176.6 0.2 6.9e-52 176.3 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE41968.1 - 0.00027 20.4 0.0 0.00044 19.7 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2147 PF09917.4 EKE41968.1 - 0.17 12.1 1.9 5.7 7.2 0.2 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) RRM_1 PF00076.17 EKE41969.1 - 5.1e-26 90.1 1.6 1.2e-12 47.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE41969.1 - 2.4e-21 75.4 0.1 1.1e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE41969.1 - 4e-06 26.5 1.0 0.0035 17.1 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_11 PF13720.1 EKE41969.1 - 0.0038 17.4 0.3 0.0038 17.4 0.2 3.3 3 2 2 5 5 5 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GRAM PF02893.15 EKE41970.1 - 8.9e-07 28.3 0.2 2.6e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 GRAM domain DUF1948 PF09185.5 EKE41970.1 - 3.6 7.2 7.9 10 5.7 0.2 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1948) ADH_zinc_N PF00107.21 EKE41971.1 - 1.2e-20 73.3 0.3 1.9e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKE41971.1 - 4.2e-14 52.2 0.8 2.8e-13 49.5 0.0 2.5 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain FAE1_CUT1_RppA PF08392.7 EKE41972.1 - 2.2e-104 348.6 0.0 2.8e-104 348.2 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EKE41972.1 - 4.8e-10 39.3 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.10 EKE41972.1 - 5.6e-09 36.0 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EKE41972.1 - 0.00082 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 EKE41972.1 - 0.024 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cpn60_TCP1 PF00118.19 EKE41973.1 - 3.8e-154 513.9 6.0 4.4e-154 513.7 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNAP PF14938.1 EKE41974.1 - 5.3e-61 206.2 21.6 6e-61 206.0 15.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EKE41974.1 - 9.5e-07 28.6 11.3 0.00096 19.0 2.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKE41974.1 - 2.3e-05 23.9 14.6 8.5e-05 22.1 3.9 2.9 3 0 0 3 3 3 2 TPR repeat TPR_6 PF13174.1 EKE41974.1 - 5.1e-05 23.4 3.7 1.8 9.2 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKE41974.1 - 0.0002 20.8 12.9 0.0095 15.5 0.9 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKE41974.1 - 0.00075 19.1 4.5 0.63 9.9 0.1 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKE41974.1 - 0.0019 18.8 8.5 0.049 14.3 1.9 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKE41974.1 - 0.0022 18.4 2.9 1.5 9.6 0.6 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EKE41974.1 - 0.0023 17.4 4.5 0.006 16.1 3.1 1.7 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_8 PF13181.1 EKE41974.1 - 0.0077 15.9 15.0 0.029 14.1 1.0 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat SPOB_a PF14689.1 EKE41974.1 - 0.009 15.5 3.7 0.23 11.0 0.0 3.3 3 1 1 4 4 3 1 Sensor_kinase_SpoOB-type, alpha-helical domain Apc3 PF12895.2 EKE41974.1 - 0.013 15.5 4.6 0.013 15.5 3.2 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Spore_YpjB PF09577.5 EKE41974.1 - 0.048 13.2 1.2 0.32 10.5 0.3 2.3 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) MTHFR PF02219.12 EKE41974.1 - 0.065 12.3 0.3 0.19 10.7 0.1 1.8 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase TPR_2 PF07719.12 EKE41974.1 - 0.09 12.7 17.8 0.35 10.9 0.7 4.1 5 1 1 6 6 4 0 Tetratricopeptide repeat SSV1_ORF_D-335 PF07935.6 EKE41974.1 - 0.1 12.3 0.3 0.62 9.8 0.0 2.4 2 1 1 3 3 3 0 ORF D-335-like protein NSF PF02071.15 EKE41974.1 - 0.64 10.8 11.4 18 6.4 0.1 5.2 4 1 1 5 5 3 0 Aromatic-di-Alanine (AdAR) repeat PhoU PF01895.14 EKE41974.1 - 1.4 9.4 5.1 3.1 8.3 0.3 3.2 2 1 1 3 3 3 0 PhoU domain RPN7 PF10602.4 EKE41974.1 - 1.5 8.1 8.8 0.41 10.0 0.4 2.6 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Peptidase_C1 PF00112.18 EKE41977.1 - 3.7e-29 102.1 7.5 3.7e-29 102.1 5.2 1.6 1 1 1 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE41977.1 - 4.4e-13 49.2 2.5 4.4e-13 49.2 1.7 2.5 3 0 0 3 3 3 1 Cathepsin propeptide inhibitor domain (I29) Pkinase PF00069.20 EKE41978.1 - 5.4e-58 196.1 5.5 1e-56 191.9 1.4 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE41978.1 - 4.2e-28 98.1 0.1 1.5e-27 96.3 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE41978.1 - 4.1e-06 25.9 0.2 6.5e-05 22.0 0.0 2.1 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EKE41978.1 - 2.7e-05 23.8 0.9 4.6e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKE41978.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kin_N PF04428.9 EKE41978.1 - 0.0022 17.4 0.0 0.0069 15.8 0.0 1.9 1 1 0 1 1 1 1 Choline kinase N terminus Kinase-like PF14531.1 EKE41978.1 - 0.0022 16.9 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like UPF0183 PF03676.9 EKE41979.1 - 0.00014 20.5 1.9 0.00014 20.5 1.3 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0183) WD40 PF00400.27 EKE41980.1 - 3.8e-07 29.7 0.3 0.0037 17.0 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE41980.1 - 0.0068 16.1 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EKE41981.1 - 0.033 14.0 5.5 0.64 9.9 0.1 3.1 4 1 0 4 4 4 0 WD domain, G-beta repeat TLD PF07534.11 EKE41982.1 - 5e-07 29.7 5.7 1.3e-06 28.4 3.9 1.6 1 0 0 1 1 1 1 TLD DUF45 PF01863.12 EKE41982.1 - 2.8 7.6 10.3 0.56 9.9 4.7 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 LRR_5 PF13306.1 EKE41983.1 - 6.6e-09 35.5 89.3 0.008 15.8 4.7 10.5 2 2 9 11 11 11 10 Leucine rich repeats (6 copies) NeuB PF03102.9 EKE41983.1 - 0.032 13.3 0.8 3.2 6.8 0.2 2.6 2 0 0 2 2 2 0 NeuB family ADK PF00406.17 EKE41984.1 - 4.4e-43 146.7 0.1 5.1e-43 146.5 0.1 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EKE41984.1 - 6.2e-11 42.7 0.2 1.2e-10 41.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE41984.1 - 9.4e-07 29.6 0.1 2.3e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKE41984.1 - 3e-06 27.1 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EKE41984.1 - 0.0006 19.2 0.1 0.12 11.7 0.0 2.1 1 1 1 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 EKE41984.1 - 0.00078 18.6 0.1 0.0015 17.6 0.1 1.4 1 1 0 1 1 1 1 Zeta toxin Bac_DnaA PF00308.13 EKE41984.1 - 0.015 14.9 0.2 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Glyco_hydro_3_C PF01915.17 EKE41984.1 - 0.042 13.3 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain NTPase_1 PF03266.10 EKE41984.1 - 0.076 12.7 0.6 0.14 11.8 0.2 1.6 2 1 0 2 2 2 0 NTPase AAA_28 PF13521.1 EKE41984.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF1103 PF06513.6 EKE41984.1 - 0.12 11.6 4.5 0.35 10.2 2.3 2.0 1 1 0 1 1 1 0 Repeat of unknown function (DUF1103) DUF4325 PF14213.1 EKE41984.1 - 0.69 9.6 3.8 7.2 6.3 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4325) UEV PF05743.8 EKE41985.1 - 4.4e-16 58.6 0.2 2.3e-15 56.3 0.0 2.3 3 0 0 3 3 3 1 UEV domain AAA_23 PF13476.1 EKE41985.1 - 0.0071 16.6 7.6 0.0071 16.6 5.2 2.0 2 0 0 2 2 2 1 AAA domain L31 PF09784.4 EKE41985.1 - 8.9 6.4 7.6 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 Ras PF00071.17 EKE41986.1 - 5e-53 178.8 0.1 5.8e-53 178.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE41986.1 - 5.7e-16 59.0 0.1 8.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE41986.1 - 1.4e-09 37.4 0.1 2.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE41986.1 - 0.0004 19.8 0.4 0.0019 17.6 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE41986.1 - 0.0017 17.5 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE41986.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ldh_1_N PF00056.18 EKE41986.1 - 0.028 14.2 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain SRPRB PF09439.5 EKE41986.1 - 0.045 12.9 0.7 0.078 12.1 0.0 1.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF3243 PF11588.3 EKE41986.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) SLS PF14611.1 EKE41986.1 - 0.1 11.9 0.2 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator RNase_P_Rpp14 PF01900.14 EKE41987.1 - 7e-13 48.4 0.0 8.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family CAP_N PF01213.14 EKE41988.1 - 5.1e-68 229.6 4.4 1.3e-67 228.3 3.1 1.6 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EKE41988.1 - 1.1e-44 151.6 9.2 1.7e-44 150.9 6.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EKE41988.1 - 0.00077 18.8 6.6 0.0015 17.9 4.6 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF1227 PF06777.6 EKE41988.1 - 0.073 12.7 0.0 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) PP2C_2 PF13672.1 EKE41989.1 - 0.0024 17.2 0.0 0.005 16.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C HR1 PF02185.11 EKE41989.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Hr1 repeat Yip1 PF04893.12 EKE41990.1 - 3.8 6.9 22.9 0.064 12.7 6.5 2.3 1 1 1 2 2 2 0 Yip1 domain PIG-F PF06699.6 EKE41990.1 - 5.9 6.7 9.4 0.44 10.4 1.7 2.2 1 1 1 2 2 2 0 GPI biosynthesis protein family Pig-F PCNP PF15473.1 EKE41991.1 - 0.014 15.7 0.3 0.014 15.7 0.2 1.8 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family DUF4285 PF14113.1 EKE41991.1 - 6.9 6.6 7.1 2.3 8.2 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4285) HSP70 PF00012.15 EKE41992.1 - 7.5e-41 139.7 7.4 7.5e-41 139.7 5.1 2.0 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 EKE41992.1 - 0.001 18.4 0.0 0.024 13.9 0.0 2.3 1 1 1 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 EKE41992.1 - 0.013 14.1 0.0 0.013 14.1 0.0 1.8 2 1 0 2 2 2 0 MreB/Mbl protein Hydantoinase_A PF01968.13 EKE41992.1 - 0.21 10.6 3.0 1.2 8.1 0.0 2.9 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase HSP70 PF00012.15 EKE41993.1 - 1.3e-10 39.8 0.0 1.5e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Ribosomal_S27e PF01667.12 EKE41994.1 - 3.7e-28 96.8 4.5 4.2e-28 96.6 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EKE41994.1 - 8.4e-06 25.0 0.3 1.2e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EKE41994.1 - 1.4e-05 24.1 1.7 3.1e-05 23.0 1.2 1.6 1 1 0 1 1 1 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EKE41994.1 - 0.00025 20.6 0.4 0.00036 20.1 0.3 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 EKE41994.1 - 0.00035 19.9 2.7 0.21 11.0 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain Lar_restr_allev PF14354.1 EKE41994.1 - 0.003 17.8 2.2 0.0036 17.5 1.5 1.3 1 1 0 1 1 1 1 Restriction alleviation protein Lar DZR PF12773.2 EKE41994.1 - 0.004 16.9 5.1 0.021 14.6 3.7 1.8 1 1 0 1 1 1 1 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 EKE41994.1 - 0.0047 16.6 0.3 0.0077 15.9 0.2 1.3 1 0 0 1 1 1 1 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.5 EKE41994.1 - 0.0054 16.1 2.6 1.1 8.7 0.2 2.3 2 0 0 2 2 2 1 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EKE41994.1 - 0.0058 16.5 3.8 0.015 15.2 2.6 1.7 1 1 0 1 1 1 1 Zinc ribbon domain HypA PF01155.14 EKE41994.1 - 0.01 15.5 1.0 0.012 15.2 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family IBR PF01485.16 EKE41994.1 - 0.012 15.4 0.6 0.012 15.4 0.4 1.4 2 0 0 2 2 1 0 IBR domain zf-FPG_IleRS PF06827.9 EKE41994.1 - 0.013 15.1 2.4 0.07 12.7 0.1 2.2 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS Yippee-Mis18 PF03226.9 EKE41994.1 - 0.015 15.3 1.3 0.086 12.8 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Auto_anti-p27 PF06677.7 EKE41994.1 - 0.018 14.8 3.1 2.2 8.0 0.3 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mu-like_Com PF10122.4 EKE41994.1 - 0.027 13.5 3.7 0.035 13.1 0.1 2.1 1 1 0 2 2 2 0 Mu-like prophage protein Com zf-CCHC PF00098.18 EKE41994.1 - 0.03 14.2 3.8 1.8 8.6 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-Mss51 PF13824.1 EKE41994.1 - 0.031 14.1 3.8 0.6 10.0 2.9 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_S27 PF01599.14 EKE41994.1 - 0.032 14.0 1.1 0.06 13.1 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S27a zf-NADH-PPase PF09297.6 EKE41994.1 - 0.036 13.5 3.9 0.15 11.5 2.7 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain ADK_lid PF05191.9 EKE41994.1 - 0.042 13.5 3.7 0.4 10.3 2.6 2.2 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-TFIIB PF13453.1 EKE41994.1 - 0.044 12.9 2.6 0.087 12.0 1.8 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF2752 PF10825.3 EKE41994.1 - 0.045 13.7 0.5 0.056 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) zf-C2H2 PF00096.21 EKE41994.1 - 0.048 14.0 2.2 2 8.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 EKE41994.1 - 0.059 13.1 4.5 0.12 12.2 3.1 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 EKE41994.1 - 0.068 12.8 0.5 0.068 12.8 0.3 2.4 2 1 1 3 3 2 0 Transcription factor S-II (TFIIS) HECT_2 PF09814.4 EKE41994.1 - 0.068 11.8 0.2 0.08 11.6 0.2 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-H2C2_2 PF13465.1 EKE41994.1 - 0.078 13.2 2.2 0.43 10.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF4182 PF13790.1 EKE41994.1 - 0.08 12.7 1.9 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) Nudix_N_2 PF14803.1 EKE41994.1 - 0.095 12.4 3.7 3.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal Nop10p PF04135.7 EKE41994.1 - 0.1 12.3 0.7 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family DUF866 PF05907.8 EKE41994.1 - 0.12 11.8 1.3 0.15 11.5 0.9 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) DUF2318 PF10080.4 EKE41994.1 - 0.13 12.0 0.8 0.15 11.8 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Zn_Tnp_IS91 PF14319.1 EKE41994.1 - 0.14 11.7 1.6 0.15 11.5 1.1 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-B_box PF00643.19 EKE41994.1 - 0.16 11.8 2.2 0.4 10.6 1.5 1.6 1 1 0 1 1 1 0 B-box zinc finger FYVE PF01363.16 EKE41994.1 - 0.16 11.8 4.5 0.22 11.4 3.1 1.3 1 1 0 1 1 1 0 FYVE zinc finger Rpr2 PF04032.11 EKE41994.1 - 0.18 11.7 1.2 2.4 8.0 0.1 2.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_4 PF13894.1 EKE41994.1 - 0.19 12.1 6.1 0.2 12.0 0.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 EKE41994.1 - 0.21 11.9 5.1 13 6.0 3.6 2.2 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zinc_ribbon_6 PF14599.1 EKE41994.1 - 0.25 11.1 2.3 0.66 9.8 1.6 1.7 1 1 0 1 1 1 0 Zinc-ribbon Prok-RING_1 PF14446.1 EKE41994.1 - 0.29 10.9 3.8 1 9.1 2.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CCHC_3 PF13917.1 EKE41994.1 - 0.3 10.8 0.4 0.3 10.8 0.3 2.6 3 0 0 3 3 3 0 Zinc knuckle zinc_ribbon_4 PF13717.1 EKE41994.1 - 0.32 10.7 6.5 0.93 9.2 0.1 2.6 3 0 0 3 3 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EKE41994.1 - 0.35 10.6 4.4 0.62 9.8 3.1 1.6 1 1 0 1 1 1 0 zinc-ribbons CpXC PF14353.1 EKE41994.1 - 0.43 10.5 3.3 2.2 8.2 0.1 2.1 1 1 2 3 3 3 0 CpXC protein zf-HIT PF04438.11 EKE41994.1 - 0.5 10.0 3.8 2.8 7.6 0.1 2.4 3 0 0 3 3 2 0 HIT zinc finger zinc_ribbon_5 PF13719.1 EKE41994.1 - 0.53 9.9 7.2 0.77 9.3 0.1 2.6 3 0 0 3 3 2 0 zinc-ribbon domain DUF1451 PF07295.6 EKE41994.1 - 0.83 9.4 2.8 0.91 9.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF2296 PF10058.4 EKE41994.1 - 0.88 9.3 3.8 9.7 6.0 0.3 2.2 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C4_Topoisom PF01396.14 EKE41994.1 - 0.96 9.0 9.0 0.81 9.2 0.3 2.5 3 0 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger DUF1610 PF07754.6 EKE41994.1 - 1.1 9.4 6.5 3.2 7.9 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-C2H2_3 PF13878.1 EKE41994.1 - 1.1 8.9 4.4 4.5 6.9 0.1 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn_Tnp_IS1 PF03811.8 EKE41994.1 - 1.2 8.6 5.1 6.6 6.3 3.6 2.1 1 1 0 1 1 1 0 InsA N-terminal domain zf-IS66 PF13005.2 EKE41994.1 - 1.6 8.8 6.4 2.5 8.1 0.1 2.2 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF2082 PF09855.4 EKE41994.1 - 1.9 8.3 5.9 1.8 8.4 0.3 2.3 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Rubredoxin PF00301.15 EKE41994.1 - 2.2 8.2 4.9 1.2 9.1 0.3 2.2 1 1 2 3 3 3 0 Rubredoxin zf-tcix PF14952.1 EKE41994.1 - 2.9 7.3 8.3 0.61 9.4 3.0 1.9 2 1 0 2 2 1 0 Putative treble-clef, zinc-finger, Zn-binding zf-ISL3 PF14690.1 EKE41994.1 - 4 7.5 8.2 1.6 8.8 0.3 2.3 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DNA_RNApol_7kD PF03604.8 EKE41994.1 - 5.1 6.6 9.2 13 5.3 4.1 2.7 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-AN1 PF01428.11 EKE41994.1 - 7.1 6.5 7.2 10 6.0 3.1 2.5 1 1 0 1 1 1 0 AN1-like Zinc finger DnaJ PF00226.26 EKE41996.1 - 5.1e-15 54.9 0.1 7.9e-15 54.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Lactamase_B_2 PF12706.2 EKE41997.1 - 4.3e-06 26.4 0.0 8.1e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKE41997.1 - 0.00036 20.2 0.2 0.00068 19.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EKE41997.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain RhoGAP PF00620.22 EKE41998.1 - 2e-08 33.9 0.4 2.4e-08 33.7 0.2 1.0 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.27 EKE41999.1 - 1.9e-36 122.6 8.1 2.6e-11 42.9 0.2 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat PD40 PF07676.7 EKE41999.1 - 0.00023 20.7 1.7 1.2 8.9 0.0 4.6 4 1 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EKE41999.1 - 0.0034 16.5 0.0 2.4 7.2 0.0 3.5 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Adaptin_N PF01602.15 EKE42002.1 - 5.6e-38 130.5 21.9 1.4e-37 129.2 15.2 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EKE42002.1 - 5.5e-07 29.7 0.3 0.017 15.3 0.1 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EKE42002.1 - 9.1e-05 22.2 0.0 0.05 13.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat UBACT PF02134.16 EKE42002.1 - 0.01 15.3 2.7 0.019 14.5 0.6 2.3 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein EamA PF00892.15 EKE42003.1 - 7.4e-07 29.2 7.5 7.4e-07 29.2 5.2 4.0 4 1 0 4 4 4 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EKE42003.1 - 1.5e-06 27.5 1.9 1.5e-06 27.5 1.3 2.2 1 1 1 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EKE42003.1 - 6.8e-06 26.2 6.1 6.8e-06 26.2 4.3 3.8 3 1 1 4 4 4 1 Multidrug resistance efflux transporter DNA_pol_E_B PF04042.11 EKE42004.1 - 1e-22 80.4 2.8 1.6e-22 79.7 1.9 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Peptidase_C54 PF03416.14 EKE42005.1 - 2.8e-63 213.6 0.0 3.5e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EKE42005.1 - 0.00048 19.3 0.1 0.0038 16.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C78 MCM PF00493.18 EKE42006.1 - 1.4e-128 428.3 1.1 2e-128 427.8 0.8 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EKE42006.1 - 2.3e-08 33.4 0.1 1.5e-06 27.5 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKE42006.1 - 0.00013 21.5 0.1 0.00032 20.2 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKE42006.1 - 0.00048 19.6 0.0 0.0018 17.7 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Pkinase PF00069.20 EKE42007.1 - 4.7e-63 212.7 0.0 1.9e-61 207.4 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42007.1 - 8e-45 152.9 0.0 3.4e-44 150.8 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42007.1 - 7.3e-09 34.9 0.0 1.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE42007.1 - 0.00065 19.5 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pepsin-I3 PF06394.8 EKE42007.1 - 0.0036 16.9 0.2 0.17 11.5 0.0 2.8 2 0 0 2 2 2 1 Pepsin inhibitor-3-like repeated domain Kdo PF06293.9 EKE42007.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.3 EKE42007.1 - 0.096 12.0 0.0 0.096 12.0 0.0 2.4 2 1 0 2 2 2 0 Protein-kinase domain of FAM69 zf-C3HC4_3 PF13920.1 EKE42008.1 - 1.3e-05 24.7 13.0 1.3e-05 24.7 9.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE42008.1 - 0.0014 18.6 13.1 0.0014 18.6 9.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 EKE42008.1 - 0.0065 15.6 1.2 0.015 14.4 0.8 1.6 1 0 0 1 1 1 1 zinc-ribbon domain H_lectin PF09458.5 EKE42008.1 - 0.014 15.0 1.5 0.046 13.3 0.0 2.5 3 0 0 3 3 3 0 H-type lectin domain Prok-RING_4 PF14447.1 EKE42008.1 - 0.053 13.0 7.8 0.14 11.7 5.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_2 PF13240.1 EKE42008.1 - 0.18 11.3 2.3 0.46 10.0 1.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.1 EKE42008.1 - 0.76 9.5 17.5 0.5 10.1 10.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain TLD PF07534.11 EKE42010.1 - 1.4e-08 34.7 1.3 2.6e-08 33.9 0.9 1.4 1 0 0 1 1 1 1 TLD Cloacin_immun PF03513.9 EKE42010.1 - 0.069 13.2 0.4 0.069 13.2 0.3 2.4 2 2 0 2 2 2 0 Cloacin immunity protein DUF2513 PF10711.4 EKE42010.1 - 0.5 10.4 6.8 1.2 9.2 0.0 2.6 1 1 1 2 2 2 0 Hypothetical protein (DUF2513) DUF1899 PF08953.6 EKE42011.1 - 1.1e-23 82.6 0.8 1.5e-23 82.2 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EKE42011.1 - 1.2e-16 59.8 4.6 9.2e-10 38.0 0.0 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Ank_2 PF12796.2 EKE42012.1 - 1.3e-20 73.5 1.1 3.9e-09 36.7 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKE42012.1 - 2.9e-14 52.0 1.2 8.1e-07 28.5 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EKE42012.1 - 1.5e-13 49.5 1.3 5.7e-05 22.9 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EKE42012.1 - 3.8e-11 42.8 2.0 0.00078 19.6 0.1 5.4 3 3 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKE42012.1 - 8.2e-11 42.1 2.8 0.00028 21.2 0.1 4.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) DNA_pol3_delta2 PF13177.1 EKE42013.1 - 1.6e-13 50.6 0.1 1.3e-11 44.4 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 EKE42013.1 - 2.7e-13 50.2 0.0 4.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EKE42013.1 - 1.9e-08 34.1 0.1 4.4e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EKE42013.1 - 1.5e-07 31.5 0.4 0.017 15.2 0.0 2.6 2 1 1 3 3 2 2 AAA domain AAA_14 PF13173.1 EKE42013.1 - 6.8e-07 29.2 0.0 2.2e-06 27.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EKE42013.1 - 7.9e-06 24.8 0.0 0.00052 18.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EKE42013.1 - 1.1e-05 24.6 0.0 3.1e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EKE42013.1 - 3.7e-05 22.9 0.0 0.00016 20.8 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EKE42013.1 - 3.8e-05 23.7 0.0 0.00032 20.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EKE42013.1 - 7.1e-05 22.4 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EKE42013.1 - 0.00072 19.2 0.0 0.00097 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKE42013.1 - 0.001 18.5 0.2 0.043 13.2 0.1 2.2 1 1 1 2 2 2 1 AAA-like domain TIP49 PF06068.8 EKE42013.1 - 0.0034 16.1 0.0 0.54 8.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EKE42013.1 - 0.0041 16.5 0.1 0.038 13.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKE42013.1 - 0.0063 16.3 0.0 0.047 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EKE42013.1 - 0.0089 15.5 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EKE42013.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EKE42013.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EKE42013.1 - 0.026 13.4 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 EKE42013.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 EKE42013.1 - 0.031 13.7 0.0 0.23 10.9 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EKE42013.1 - 0.041 13.3 0.0 0.076 12.4 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EKE42013.1 - 0.053 14.3 0.1 0.12 13.1 0.0 1.8 2 1 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 EKE42013.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Bac_DnaA PF00308.13 EKE42013.1 - 0.077 12.6 0.5 0.42 10.2 0.0 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.17 EKE42013.1 - 0.13 12.4 0.0 0.39 10.8 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EKE42013.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RecR PF02132.10 EKE42013.1 - 0.59 9.6 2.6 2.6 7.5 0.1 2.6 2 0 0 2 2 2 0 RecR protein Mating_N PF12731.2 EKE42014.1 - 0.0062 16.3 0.4 1.2 9.0 0.1 3.2 3 0 0 3 3 3 1 Mating-type protein beta 1 DivIC PF04977.10 EKE42014.1 - 0.039 13.4 1.0 0.1 12.1 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator IF-2B PF01008.12 EKE42014.1 - 0.051 12.5 0.4 0.086 11.8 0.0 1.5 2 0 0 2 2 2 0 Initiation factor 2 subunit family IncA PF04156.9 EKE42014.1 - 0.12 11.9 4.4 0.16 11.5 0.2 2.2 2 0 0 2 2 2 0 IncA protein BLOC1_2 PF10046.4 EKE42014.1 - 0.37 10.9 7.1 9.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 I_LWEQ PF01608.12 EKE42015.1 - 1.4e-25 90.0 6.4 1.4e-25 90.0 4.4 5.8 5 2 1 6 6 6 1 I/LWEQ domain FERM_N PF09379.5 EKE42015.1 - 3.8e-11 42.8 3.5 1e-10 41.5 1.5 2.5 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 EKE42015.1 - 1.4e-06 28.4 0.1 1.4e-06 28.4 0.1 3.9 5 1 0 5 5 5 1 FERM central domain Ras PF00071.17 EKE42016.1 - 4.1e-11 42.5 0.0 5.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EKE42016.1 - 0.009 15.4 0.9 0.011 15.2 0.6 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EKE42016.1 - 0.0095 16.4 0.5 0.048 14.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Thioredoxin_6 PF13848.1 EKE42016.1 - 0.044 13.5 0.9 0.052 13.3 0.6 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Rhomboid PF01694.17 EKE42017.1 - 9.4e-11 41.9 13.9 9.4e-11 41.9 9.6 2.6 2 1 1 3 3 3 1 Rhomboid family DnaJ PF00226.26 EKE42018.1 - 6e-21 73.9 0.3 6e-21 73.9 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 EKE42018.1 - 8.7e-10 38.5 4.8 4.5e-06 26.6 0.2 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain HCaRG PF07258.9 EKE42019.1 - 0.0005 19.6 0.1 0.0025 17.4 0.1 1.9 1 1 0 1 1 1 1 HCaRG protein BssS PF13991.1 EKE42019.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 BssS protein family DUF1230 PF06799.6 EKE42020.1 - 0.0032 17.3 1.7 0.0032 17.3 1.2 3.8 2 1 0 3 3 3 1 Protein of unknown function (DUF1230) UDG PF03167.14 EKE42021.1 - 3.3e-22 78.5 0.0 4.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ras PF00071.17 EKE42022.1 - 4.7e-10 39.0 1.9 1.7e-08 34.0 1.0 2.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKE42022.1 - 5.2e-08 33.3 0.8 1.3e-07 32.1 0.5 1.7 1 1 0 1 1 1 1 Miro-like protein RhoGAP PF00620.22 EKE42022.1 - 0.13 11.8 4.4 0.29 10.7 1.3 2.2 2 0 0 2 2 2 0 RhoGAP domain eIF3_subunit PF08597.5 EKE42023.1 - 2.2e-22 79.8 21.2 2.7e-22 79.5 14.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SRI PF08236.6 EKE42023.1 - 0.4 10.6 9.3 1.7 8.6 2.0 2.5 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain GDPD PF03009.12 EKE42025.1 - 2.5e-28 99.2 0.0 1.2e-27 97.0 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family UNC-93 PF05978.11 EKE42025.1 - 0.086 12.3 1.8 0.17 11.3 1.2 1.4 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 GCC2_GCC3 PF07699.8 EKE42026.1 - 1.4e-11 43.7 14.0 1.7e-09 37.0 2.6 5.7 1 1 5 6 6 6 3 GCC2 and GCC3 EphA2_TM PF14575.1 EKE42026.1 - 0.00024 21.4 3.2 0.00085 19.6 2.2 2.0 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EKE42026.1 - 0.0021 17.7 2.3 0.0034 17.1 1.6 1.3 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.6 EKE42026.1 - 0.0088 15.6 1.1 0.015 14.9 0.7 1.3 1 0 0 1 1 1 1 Protocadherin Chordopox_A13L PF05961.6 EKE42026.1 - 0.016 15.1 2.8 0.037 13.9 2.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Rax2 PF12768.2 EKE42026.1 - 0.018 14.2 0.6 0.026 13.7 0.4 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity NCD3G PF07562.9 EKE42026.1 - 0.032 13.9 40.4 0.3 10.8 1.5 5.4 3 1 0 5 5 5 0 Nine Cysteines Domain of family 3 GPCR DUF1191 PF06697.7 EKE42026.1 - 0.037 12.8 0.1 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Ninjurin PF04923.7 EKE42026.1 - 0.04 13.6 1.4 0.071 12.8 1.0 1.3 1 0 0 1 1 1 0 Ninjurin DUF2611 PF11022.3 EKE42026.1 - 0.053 13.5 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) PGG PF13962.1 EKE42026.1 - 0.068 12.7 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function LRRC37AB_C PF14914.1 EKE42026.1 - 0.093 12.1 4.0 0.19 11.1 2.8 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain gpUL132 PF11359.3 EKE42026.1 - 0.41 9.9 2.4 0.59 9.4 1.6 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4389 PF14333.1 EKE42026.1 - 1.8 8.2 6.1 0.24 11.1 1.3 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4389) PspB PF06667.7 EKE42026.1 - 2.1 8.3 4.6 4.7 7.2 3.2 1.6 1 1 0 1 1 1 0 Phage shock protein B Baculo_11_kDa PF06143.6 EKE42026.1 - 5.5 6.4 10.3 0.2 11.0 2.9 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Spc97_Spc98 PF04130.8 EKE42027.1 - 0.00091 17.6 0.3 0.00098 17.5 0.2 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family RD3 PF14473.1 EKE42027.1 - 0.0041 16.5 0.6 0.0046 16.4 0.4 1.1 1 0 0 1 1 1 1 RD3 protein LRR_5 PF13306.1 EKE42028.1 - 3.6e-155 508.5 132.9 1.4e-30 105.6 9.1 8.6 4 3 6 10 10 10 10 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42028.1 - 8.9e-60 198.3 20.5 3.8e-08 32.9 0.0 14.2 5 4 12 17 17 17 16 Leucine rich repeat UBA PF00627.26 EKE42030.1 - 0.0088 15.8 0.1 0.022 14.5 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain NLE PF08154.7 EKE42030.1 - 0.029 14.3 0.3 0.093 12.7 0.2 1.8 1 0 0 1 1 1 0 NLE (NUC135) domain VWA_2 PF13519.1 EKE42031.1 - 4.1e-10 40.0 0.1 1.1e-09 38.6 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EKE42031.1 - 7.8e-08 32.1 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EKE42031.1 - 0.00017 20.8 6.9 0.36 10.5 1.6 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-Nse PF11789.3 EKE42032.1 - 0.0058 16.1 0.1 0.025 14.0 0.0 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3385 PF11865.3 EKE42033.1 - 3.3e-29 101.8 0.1 3.3e-29 101.8 0.1 5.2 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.1 EKE42033.1 - 8.1e-11 42.0 0.0 9.4e-05 22.6 0.0 5.1 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EKE42033.1 - 7.3e-07 28.7 0.0 0.22 11.6 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EKE42033.1 - 2.8e-05 24.4 1.1 5.8 7.5 0.0 6.9 8 3 1 9 9 9 2 HEAT-like repeat CLASP_N PF12348.3 EKE42033.1 - 0.0082 15.5 7.1 2.3 7.5 0.0 5.3 3 1 3 6 6 6 1 CLASP N terminal MOR2-PAG1_C PF14225.1 EKE42033.1 - 0.011 15.5 15.9 0.22 11.2 0.6 4.4 3 1 0 4 4 4 0 Cell morphogenesis C-terminal TraD PF06412.6 EKE42033.1 - 0.017 14.7 0.0 0.12 11.9 0.0 2.4 3 0 0 3 3 3 0 Conjugal transfer protein TraD Cohesin_HEAT PF12765.2 EKE42033.1 - 0.094 12.6 0.0 0.33 10.9 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion V-ATPase_H_C PF11698.3 EKE42033.1 - 1.6 8.6 5.9 4.6 7.1 0.0 4.1 5 0 0 5 5 5 0 V-ATPase subunit H UNC45-central PF11701.3 EKE42033.1 - 4.5 6.9 13.7 8.1 6.0 0.2 4.7 4 2 1 5 5 5 0 Myosin-binding striated muscle assembly central Rsbr_N PF08678.5 EKE42034.1 - 0.094 12.6 1.0 0.72 9.7 0.4 2.1 1 1 1 2 2 2 0 Rsbr N terminal DNA_pol3_delta2 PF13177.1 EKE42035.1 - 4.9e-09 36.0 1.7 1.4e-08 34.5 0.1 2.3 2 2 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EKE42035.1 - 1.5e-08 34.4 0.2 1.3e-07 31.4 0.0 2.5 3 1 0 3 3 3 1 Replication factor C C-terminal domain PTPlike_phytase PF14566.1 EKE42035.1 - 0.0018 18.3 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Inositol hexakisphosphate Sigma54_activ_2 PF14532.1 EKE42035.1 - 0.018 15.0 0.0 0.22 11.5 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain TPR_14 PF13428.1 EKE42036.1 - 3.2e-13 49.0 0.1 0.14 12.8 0.0 7.4 6 2 3 9 9 8 3 Tetratricopeptide repeat Suf PF05843.9 EKE42036.1 - 4.9e-10 39.6 28.8 3.2e-05 23.8 2.4 5.3 1 1 1 3 3 3 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EKE42036.1 - 3e-08 33.8 0.1 0.00011 22.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKE42036.1 - 1.3e-05 25.7 1.2 0.0031 18.1 0.1 4.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKE42036.1 - 0.00027 20.5 7.8 0.17 11.8 0.0 5.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKE42036.1 - 0.0036 17.2 3.7 0.1 12.5 0.2 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 EKE42036.1 - 0.03 14.0 27.9 1.7 8.4 0.2 7.3 6 1 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_11 PF13414.1 EKE42036.1 - 0.035 13.7 4.7 0.74 9.5 0.0 3.9 4 1 2 6 6 6 0 TPR repeat TPR_7 PF13176.1 EKE42036.1 - 0.64 9.9 3.2 2 8.4 0.2 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EKE42036.1 - 0.75 9.5 22.9 3.2 7.5 0.5 5.8 4 2 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 EKE42036.1 - 1.5 9.4 3.7 17 6.1 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GCD14 PF08704.5 EKE42037.1 - 1.6e-47 162.0 0.0 2e-43 148.6 0.0 2.0 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 EKE42037.1 - 0.00068 20.4 0.0 0.00093 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE42037.1 - 0.0044 16.6 0.2 0.01 15.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE42037.1 - 0.0045 17.5 0.0 0.0063 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE42037.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N-Term_TEN PF11474.3 EKE42037.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 2 0 0 2 2 2 0 Telomerase reverse transcriptase TEN domain MMPL PF03176.10 EKE42039.1 - 6.8e-68 228.8 0.1 1.1e-34 119.6 0.0 2.5 2 1 0 2 2 2 2 MMPL family Cyclin_N PF00134.18 EKE42040.1 - 2.5e-36 124.0 2.4 2.8e-33 114.1 0.6 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EKE42040.1 - 1e-27 96.4 0.1 2e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pox_A8 PF04745.7 EKE42040.1 - 0.018 13.9 0.6 0.027 13.3 0.4 1.2 1 0 0 1 1 1 0 VITF-3 subunit protein DUF4557 PF15101.1 EKE42041.1 - 0.1 12.4 3.2 0.093 12.5 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3708 PF12501.3 EKE42042.1 - 4.2 7.1 5.4 11 5.8 0.1 2.1 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Abhydrolase_6 PF12697.2 EKE42043.1 - 6.8e-07 29.3 0.0 9.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE42043.1 - 3.8e-05 23.3 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKE42043.1 - 0.0041 16.8 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family CENP-F_leu_zip PF10473.4 EKE42044.1 - 0.003 17.4 8.2 0.0036 17.1 5.7 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rsd_AlgQ PF04353.8 EKE42044.1 - 0.0073 16.0 1.9 0.01 15.5 1.3 1.2 1 1 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CCDC155 PF14662.1 EKE42044.1 - 0.013 15.1 8.9 0.015 14.9 5.2 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF904 PF06005.7 EKE42044.1 - 0.014 15.7 10.8 0.014 15.7 7.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF3770 PF12603.3 EKE42044.1 - 0.018 14.1 1.7 0.02 14.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) ATG16 PF08614.6 EKE42044.1 - 0.02 14.7 6.8 0.022 14.5 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF812 PF05667.6 EKE42044.1 - 0.028 12.9 7.7 0.03 12.8 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tup_N PF08581.5 EKE42044.1 - 0.049 13.8 10.4 0.04 14.0 4.7 2.1 1 1 1 2 2 2 0 Tup N-terminal Atg14 PF10186.4 EKE42044.1 - 0.076 11.9 6.7 0.079 11.8 4.6 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EKE42044.1 - 0.087 12.3 6.7 0.3 10.6 4.6 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 EKE42044.1 - 0.13 12.2 8.3 5.7 6.9 0.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor Prp19 PF08606.6 EKE42044.1 - 0.17 11.6 3.8 1.2 8.8 0.3 2.2 1 1 1 2 2 2 0 Prp19/Pso4-like GrpE PF01025.14 EKE42044.1 - 0.18 11.3 6.2 0.33 10.4 4.3 1.6 1 1 0 1 1 1 0 GrpE Baculo_PEP_C PF04513.7 EKE42044.1 - 0.19 11.5 1.3 0.34 10.7 0.8 1.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EKE42044.1 - 0.2 11.2 11.3 0.27 10.7 7.8 1.4 1 1 0 1 1 1 0 IncA protein DUF745 PF05335.8 EKE42044.1 - 0.23 10.9 3.6 0.28 10.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) UPF0242 PF06785.6 EKE42044.1 - 0.27 9.8 5.3 0.3 9.7 3.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) HD_3 PF13023.1 EKE42044.1 - 0.31 10.7 2.8 0.36 10.5 1.9 1.1 1 0 0 1 1 1 0 HD domain DUF3074 PF11274.3 EKE42044.1 - 0.39 10.3 3.5 0.36 10.4 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3074) Fib_alpha PF08702.5 EKE42044.1 - 0.39 10.8 7.5 0.46 10.6 5.2 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COMP PF11598.3 EKE42044.1 - 0.42 10.7 2.8 6.4 6.9 0.7 2.9 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein DUF1635 PF07795.6 EKE42044.1 - 0.55 9.5 5.8 0.6 9.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Viral_P18 PF04521.8 EKE42044.1 - 0.81 9.1 3.6 1.1 8.7 2.3 1.4 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein APG6 PF04111.7 EKE42044.1 - 0.85 8.6 10.8 0.92 8.4 7.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DNA_topoisoIV PF00521.15 EKE42044.1 - 0.87 8.3 7.2 0.93 8.2 5.0 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF972 PF06156.8 EKE42044.1 - 0.98 9.7 6.8 1.7 9.0 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Occludin_ELL PF07303.8 EKE42044.1 - 1.1 10.0 6.1 2 9.1 4.1 1.5 1 1 0 1 1 1 0 Occludin homology domain FlxA PF14282.1 EKE42044.1 - 2.1 8.3 11.4 4 7.4 7.9 1.6 1 1 0 1 1 1 0 FlxA-like protein DUF342 PF03961.8 EKE42044.1 - 2.4 6.4 7.7 2.5 6.4 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 EKE42044.1 - 2.7 8.4 8.7 4.1 7.8 4.4 2.3 1 1 2 3 3 3 0 SlyX bZIP_2 PF07716.10 EKE42044.1 - 6.5 6.6 8.3 2.1 8.2 3.1 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Ras PF00071.17 EKE42047.1 - 1.3e-15 57.1 0.6 1.5e-15 56.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42047.1 - 0.0001 22.7 0.1 0.00016 22.1 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EKE42047.1 - 0.0016 18.2 0.1 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 EKE42047.1 - 0.0034 16.8 0.1 0.0046 16.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Beta-Casp PF10996.3 EKE42048.1 - 1.9e-10 40.7 0.0 1.9e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.1 EKE42048.1 - 3e-07 30.7 10.8 5.3e-07 29.9 0.1 3.1 2 1 1 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal DUF972 PF06156.8 EKE42048.1 - 4.3 7.7 13.5 23 5.4 8.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Flavokinase PF01687.12 EKE42049.1 - 2.1e-34 118.0 1.3 2.4e-34 117.8 0.9 1.0 1 0 0 1 1 1 1 Riboflavin kinase IL7 PF01415.11 EKE42049.1 - 0.038 13.6 0.3 0.061 12.9 0.2 1.3 1 0 0 1 1 1 0 Interleukin 7/9 family DUF806 PF05657.6 EKE42049.1 - 0.1 12.6 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF806) RRM_1 PF00076.17 EKE42050.1 - 1.2e-35 120.9 7.7 1.5e-09 37.3 0.2 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE42050.1 - 4.1e-32 109.9 0.1 6.5e-08 32.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42050.1 - 3.4e-16 58.8 6.0 9.4e-07 28.5 0.0 4.7 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKE42050.1 - 7e-05 22.5 2.7 1.9 8.3 0.0 4.5 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif PABP PF00658.13 EKE42050.1 - 0.00035 20.1 0.0 0.00093 18.8 0.0 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EKE42050.1 - 0.00074 19.3 9.2 0.14 12.0 1.0 4.4 3 1 1 4 4 4 1 RNA binding motif DUF1987 PF09345.5 EKE42050.1 - 0.056 13.2 0.9 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) DUF4456 PF14644.1 EKE42050.1 - 1.5 8.0 6.3 11 5.2 0.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4456) Ribosomal_S19 PF00203.16 EKE42051.1 - 3.4e-29 100.2 0.5 5.1e-29 99.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 DUF1253 PF06862.7 EKE42054.1 - 9.1e-110 367.0 14.3 9.1e-110 367.0 9.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) DUF3238 PF11579.3 EKE42055.1 - 0.045 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) Peptidase_C54 PF03416.14 EKE42056.1 - 5.1e-17 61.9 0.3 1.1e-16 60.7 0.1 1.6 1 1 1 2 2 2 1 Peptidase family C54 Peptidase_C78 PF07910.8 EKE42056.1 - 0.02 14.0 2.2 0.099 11.7 1.6 2.1 1 1 0 1 1 1 0 Peptidase family C78 DUF4176 PF13780.1 EKE42056.1 - 0.036 13.7 0.3 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) DUF3878 PF12994.2 EKE42056.1 - 0.064 12.4 0.9 18 4.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3878) HSF_DNA-bind PF00447.12 EKE42058.1 - 2e-29 101.7 0.2 4.2e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding COG5 PF10392.4 EKE42058.1 - 0.025 14.5 0.3 5 7.0 0.1 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 TMF_DNA_bd PF12329.3 EKE42058.1 - 0.058 13.2 1.7 0.12 12.1 1.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SAC3_GANP PF03399.11 EKE42059.1 - 1.6e-38 132.3 5.8 2.1e-38 131.9 4.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Bromodomain PF00439.20 EKE42060.1 - 2.6e-22 78.5 0.5 6.5e-22 77.2 0.4 1.7 1 0 0 1 1 1 1 Bromodomain RE_AccI PF09545.5 EKE42060.1 - 0.0025 16.4 0.2 0.0031 16.1 0.1 1.2 1 0 0 1 1 1 1 AccI restriction endonuclease BP28CT PF08146.7 EKE42060.1 - 0.15 11.8 1.7 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 BP28CT (NUC211) domain PIP5K PF01504.13 EKE42061.1 - 4.3e-54 183.2 2.7 4.7e-54 183.1 0.8 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Med12-PQL PF12144.3 EKE42061.1 - 0.13 11.6 1.7 0.23 10.8 1.2 1.4 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain IBN_N PF03810.14 EKE42062.1 - 0.0046 16.8 1.8 0.021 14.7 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HSP70 PF00012.15 EKE42063.1 - 6.5e-74 248.9 13.6 9.8e-74 248.3 9.4 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKE42063.1 - 9.2e-10 37.6 2.6 1.3e-08 33.8 1.2 2.8 2 1 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.15 EKE42063.1 - 4.7e-06 26.0 0.1 0.065 12.5 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 EKE42063.1 - 0.0039 17.0 1.5 8.1 6.3 0.1 3.6 3 0 0 3 3 3 1 Cell division protein FtsA Chal_sti_synt_C PF02797.10 EKE42063.1 - 0.042 13.7 0.2 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain Sec23_trunk PF04811.10 EKE42064.1 - 1.4e-16 60.6 0.1 3.3e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EKE42064.1 - 1.2e-13 51.3 0.1 2.7e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EKE42064.1 - 1.8e-10 40.1 7.2 2.1e-10 39.9 3.6 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger VWA_2 PF13519.1 EKE42064.1 - 0.0003 20.9 0.0 0.04 14.0 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE42064.1 - 0.0017 18.1 0.0 0.0079 15.9 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain IF-2B PF01008.12 EKE42065.1 - 6.1e-36 123.8 11.2 9.3e-34 116.6 7.8 2.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Bap31 PF05529.7 EKE42065.1 - 1.6e-05 24.4 28.7 0.0073 15.7 19.9 2.4 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like Zip PF02535.17 EKE42065.1 - 0.31 9.9 3.1 0.62 9.0 2.2 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.1 EKE42065.1 - 0.54 10.5 7.3 0.89 9.8 5.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2201_N PF13203.1 EKE42065.1 - 2.2 7.3 7.5 3.2 6.8 5.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DCP1 PF06058.8 EKE42066.1 - 0.00037 20.5 0.0 0.00044 20.2 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Viral_protease PF08715.5 EKE42066.1 - 0.02 13.9 0.2 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Papain like viral protease HHH_7 PF14635.1 EKE42067.1 - 6e-13 48.8 0.2 1.6e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Peptidase_C13 PF01650.13 EKE42068.1 - 8.5e-32 110.4 0.5 9.7e-32 110.2 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.17 EKE42068.1 - 0.036 13.7 0.1 0.068 12.8 0.1 1.5 1 1 0 1 1 1 0 Caspase domain Adaptin_N PF01602.15 EKE42069.1 - 2.2e-113 379.3 13.0 3.1e-113 378.8 9.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EKE42069.1 - 2.7e-17 63.1 2.8 2.7e-17 63.1 2.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EKE42069.1 - 0.0013 18.9 0.0 0.4 11.0 0.0 3.7 3 1 0 3 3 3 1 HEAT repeats TIP120 PF08623.5 EKE42069.1 - 2.3 7.7 8.5 4.6 6.8 0.4 4.1 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) TRM13 PF05206.9 EKE42070.1 - 5.2e-39 134.0 1.0 5.2e-39 134.0 0.7 2.7 3 1 0 3 3 3 1 Methyltransferase TRM13 Methyltransf_32 PF13679.1 EKE42070.1 - 7.3e-09 35.4 0.1 7.3e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Disulph_isomer PF06491.6 EKE42070.1 - 0.021 14.6 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Disulphide isomerase zf-U11-48K PF05253.7 EKE42070.1 - 2.3 8.0 8.7 0.06 13.0 1.2 2.1 2 1 0 2 2 2 0 U11-48K-like CHHC zinc finger MutS_V PF00488.16 EKE42071.1 - 3.1e-36 124.9 0.0 6.7e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EKE42071.1 - 5.1e-17 62.3 0.4 1.3e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain III PAP2 PF01569.16 EKE42072.1 - 1.1e-20 73.6 1.6 1.1e-20 73.6 1.1 1.9 1 1 1 2 2 2 1 PAP2 superfamily NatB_MDM20 PF09797.4 EKE42073.1 - 4.8e-17 61.7 21.8 5.4e-16 58.2 4.1 3.1 1 1 2 3 3 3 3 N-acetyltransferase B complex (NatB) non catalytic subunit MRP-S27 PF10037.4 EKE42074.1 - 0.0029 16.6 4.4 0.0033 16.4 3.1 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 F-actin_cap_A PF01267.12 EKE42074.1 - 0.015 14.3 1.5 0.017 14.2 1.0 1.1 1 0 0 1 1 1 0 F-actin capping protein alpha subunit nsp9 PF08710.5 EKE42074.1 - 0.053 13.6 0.2 0.065 13.3 0.1 1.1 1 0 0 1 1 1 0 nsp9 replicase SUFU_C PF12470.3 EKE42074.1 - 0.13 11.8 1.4 0.15 11.6 1.0 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain PHB_acc_N PF07879.6 EKE42074.1 - 0.71 9.6 3.2 0.29 10.8 0.3 1.8 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain Abhydrolase_6 PF12697.2 EKE42077.1 - 1.9e-16 60.6 0.0 2.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE42077.1 - 7.1e-16 58.2 0.0 1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKE42077.1 - 7.4e-16 57.7 0.0 1.7e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EKE42077.1 - 2.8e-08 33.6 0.0 4.8e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2305 PF10230.4 EKE42077.1 - 0.019 14.3 0.1 0.49 9.7 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) SRPRB PF09439.5 EKE42077.1 - 0.023 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NHL PF01436.16 EKE42078.1 - 1e-10 40.9 0.2 0.0031 17.4 0.0 4.4 4 0 0 4 4 4 2 NHL repeat SGL PF08450.7 EKE42078.1 - 0.015 14.6 0.0 1.2 8.4 0.0 2.5 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region G10 PF01125.12 EKE42078.1 - 0.32 10.5 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 G10 protein RabGAP-TBC PF00566.13 EKE42079.1 - 2.6e-23 82.6 1.3 2.6e-23 82.6 0.9 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EKE42079.1 - 4e-13 49.0 2.9 6.3e-13 48.4 2.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42079.1 - 2.2e-09 36.7 1.3 2.7e-08 33.2 0.9 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase YjgP_YjgQ PF03739.9 EKE42080.1 - 0.21 10.2 1.6 0.59 8.8 1.1 1.8 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Rotavirus_VP1 PF12289.3 EKE42081.1 - 0.034 13.7 0.1 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 Rotavirus VP1 structural protein DUF3915 PF13054.1 EKE42081.1 - 0.078 12.9 0.7 0.15 11.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF234 PF03008.9 EKE42081.1 - 0.092 12.8 0.6 0.18 11.9 0.2 1.7 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function LRR_5 PF13306.1 EKE42082.1 - 6.2e-168 549.8 124.6 2.3e-35 121.0 10.0 5.4 1 1 5 6 6 6 6 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42082.1 - 6e-48 160.4 43.2 5.8e-07 29.1 0.3 11.7 4 4 12 16 16 16 16 Leucine rich repeat BHD_3 PF10405.4 EKE42082.1 - 0.056 13.1 0.0 0.68 9.6 0.0 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 Sel1 PF08238.7 EKE42083.1 - 2.8e-16 59.5 1.1 0.053 14.1 0.0 7.4 8 0 0 8 8 8 4 Sel1 repeat CH PF00307.26 EKE42083.1 - 4.7e-12 45.9 2.2 4.4e-06 26.7 0.1 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain TPR_1 PF00515.23 EKE42083.1 - 0.0046 16.5 3.0 0.34 10.5 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKE42083.1 - 0.013 15.3 1.3 17 5.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 EKE42084.1 - 1.1e-77 261.4 0.1 1.7e-77 260.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DENN PF02141.16 EKE42085.1 - 3.9e-22 78.8 8.6 3.9e-22 78.8 6.0 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain SPA PF08616.5 EKE42085.1 - 3.9e-07 29.7 1.2 3.9e-07 29.7 0.8 1.9 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 EKE42085.1 - 0.0054 15.2 2.2 0.42 9.0 0.5 2.4 1 1 1 2 2 2 2 Transport protein Avl9 RIO1 PF01163.17 EKE42086.1 - 2.9e-69 232.2 0.3 2.9e-69 232.2 0.2 2.9 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 EKE42086.1 - 0.014 15.1 0.1 0.097 12.3 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Prismane PF03063.15 EKE42086.1 - 0.05 11.9 1.7 0.18 10.1 0.6 2.3 2 1 0 2 2 2 0 Prismane/CO dehydrogenase family SSFA2_C PF14723.1 EKE42086.1 - 0.23 11.2 5.9 0.41 10.3 4.1 1.4 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus WD40 PF00400.27 EKE42088.1 - 3.4e-21 74.2 4.3 0.0015 18.3 0.2 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat Ras PF00071.17 EKE42089.1 - 2.1e-59 199.5 0.7 2.5e-59 199.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42089.1 - 9.4e-18 64.8 0.1 1.8e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE42089.1 - 4.5e-15 55.3 0.1 5.6e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE42089.1 - 3.8e-07 30.0 0.0 6.3e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE42089.1 - 6.2e-07 29.0 0.1 1.1e-06 28.1 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE42089.1 - 2.3e-05 23.6 0.1 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE42089.1 - 0.00034 20.7 0.1 0.001 19.2 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EKE42089.1 - 0.00042 19.4 0.0 0.00048 19.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.1 EKE42089.1 - 0.0019 18.2 0.1 0.029 14.3 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EKE42089.1 - 0.0032 17.1 0.3 0.0062 16.2 0.1 1.5 1 1 1 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 EKE42089.1 - 0.0049 16.3 0.1 0.018 14.5 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EKE42089.1 - 0.0053 15.9 0.0 0.013 14.6 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EKE42089.1 - 0.0065 16.7 0.1 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EKE42089.1 - 0.0087 15.2 0.1 0.017 14.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EKE42089.1 - 0.011 15.4 0.1 0.018 14.7 0.1 1.4 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.1 EKE42089.1 - 0.016 15.1 0.8 0.48 10.3 0.5 2.2 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EKE42089.1 - 0.017 14.7 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 EKE42089.1 - 0.025 14.4 0.1 0.06 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EKE42089.1 - 0.08 12.3 0.2 4.2 6.7 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.4 EKE42089.1 - 0.086 11.7 0.2 0.85 8.4 0.0 2.3 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.9 EKE42089.1 - 0.11 12.1 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EKE42089.1 - 0.25 11.2 1.5 0.45 10.4 1.0 1.7 1 1 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.15 EKE42091.1 - 8.8e-24 83.8 0.2 1.9e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EKE42091.1 - 1.4e-15 58.0 0.1 3.7e-15 56.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKE42091.1 - 4e-15 56.8 3.6 3.4e-13 50.5 1.7 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE42091.1 - 3.2e-13 49.4 0.5 1e-12 47.8 0.1 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKE42091.1 - 0.00016 21.3 7.6 0.072 12.6 0.1 3.5 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase Acetyltransf_7 PF13508.1 EKE42092.1 - 1.6e-11 44.1 0.7 2.2e-11 43.7 0.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKE42092.1 - 2.2e-06 27.5 0.1 3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EKE42092.1 - 0.00022 21.7 0.0 0.012 16.1 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE42092.1 - 0.00025 20.8 0.2 0.0028 17.5 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE42092.1 - 0.00026 21.1 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKE42092.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EKE42092.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Autoind_synth PF00765.12 EKE42092.1 - 0.0087 15.3 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Autoinducer synthetase SHQ1 PF04925.10 EKE42092.1 - 0.0095 15.4 0.6 0.015 14.8 0.0 1.5 2 0 0 2 2 2 1 SHQ1 protein GNAT_acetyltr_2 PF13718.1 EKE42092.1 - 0.028 13.7 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_13 PF13880.1 EKE42092.1 - 0.032 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase WD40 PF00400.27 EKE42093.1 - 0.09 12.7 0.1 3.7 7.5 0.0 3.3 3 1 0 3 3 3 0 WD domain, G-beta repeat DRMBL PF07522.9 EKE42094.1 - 9.1e-17 61.0 0.3 1.6e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EKE42094.1 - 1.2e-08 34.7 0.1 7.8e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKE42094.1 - 0.0045 16.6 0.1 0.0099 15.5 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RabGAP-TBC PF00566.13 EKE42095.1 - 1.1e-39 136.1 5.6 1.5e-39 135.6 3.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TRAM1 PF08390.6 EKE42095.1 - 0.008 15.6 0.3 0.018 14.5 0.2 1.6 1 0 0 1 1 1 1 TRAM1-like protein adh_short PF00106.20 EKE42096.1 - 5.2e-25 88.2 0.0 8.8e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKE42096.1 - 3.7e-11 43.0 0.0 1e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EKE42096.1 - 6.7e-08 32.5 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKE42096.1 - 4.9e-06 26.6 0.0 9.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EKE42096.1 - 0.0041 16.2 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 EKE42096.1 - 0.0045 17.3 0.0 0.0093 16.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EKE42096.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EKE42096.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family dTMP_synthase PF02593.9 EKE42096.1 - 0.037 13.3 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Thymidylate synthase Glyco_tran_WecB PF03808.8 EKE42096.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_2 PF03446.10 EKE42096.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Tmemb_185A PF10269.4 EKE42097.1 - 0.00037 20.1 14.1 0.00037 20.1 9.8 3.3 1 1 2 3 3 3 2 Transmembrane Fragile-X-F protein F-box PF00646.28 EKE42097.1 - 0.0091 15.6 0.6 0.024 14.2 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKE42097.1 - 0.024 14.3 0.3 0.064 12.9 0.2 1.8 1 0 0 1 1 1 0 F-box-like Rad1 PF02144.11 EKE42098.1 - 1.3e-13 50.3 5.2 3.4e-07 29.3 0.1 2.2 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Ank_2 PF12796.2 EKE42099.1 - 1.4e-18 66.9 0.0 8.7e-11 42.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKE42099.1 - 1.1e-15 56.1 0.0 5.5e-05 23.0 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 EKE42099.1 - 1.3e-14 53.1 0.0 2.9e-06 26.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Patatin PF01734.17 EKE42099.1 - 5.6e-14 52.5 0.0 2e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Ank_4 PF13637.1 EKE42099.1 - 3.7e-12 46.4 0.0 2.8e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE42099.1 - 8.9e-10 38.5 0.0 0.0051 17.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) tRNA-synt_1b PF00579.20 EKE42101.1 - 0.012 14.7 0.0 0.047 12.8 0.0 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (W and Y) Rhabdo_M1 PF03342.8 EKE42101.1 - 0.02 14.0 0.5 0.041 13.0 0.3 1.4 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) RRM_1 PF00076.17 EKE42101.1 - 0.035 13.7 0.3 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec20 PF03908.8 EKE42101.1 - 0.9 9.2 7.8 14 5.4 1.4 3.7 3 1 0 3 3 3 0 Sec20 KAP PF05804.7 EKE42102.1 - 1.5e-11 42.9 19.9 3.1e-05 22.1 1.4 4.1 1 1 0 3 3 3 3 Kinesin-associated protein (KAP) RICTOR_M PF14666.1 EKE42102.1 - 0.00012 21.1 0.9 0.43 9.5 0.0 3.8 2 2 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain DUF384 PF04064.8 EKE42102.1 - 0.2 11.2 2.7 1.9 8.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF384) Abhydrolase_6 PF12697.2 EKE42103.1 - 6.8e-15 55.5 0.0 9.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKE42103.1 - 4.9e-11 42.6 0.1 7.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKE42103.1 - 1.7e-08 34.3 0.0 2.4e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EKE42103.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.17 EKE42103.1 - 0.0022 17.7 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 EKE42103.1 - 0.033 14.3 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF818 PF05677.7 EKE42103.1 - 0.079 11.6 0.4 0.15 10.7 0.3 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Lipase_3 PF01764.20 EKE42103.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EKE42103.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RabGAP-TBC PF00566.13 EKE42105.1 - 2.8e-25 89.0 7.9 6.1e-25 87.9 5.5 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_pol_I_A49 PF06870.7 EKE42105.1 - 0.027 13.0 0.2 0.048 12.2 0.1 1.3 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor LSM PF01423.17 EKE42107.1 - 3.2e-13 49.0 0.5 5.2e-13 48.3 0.4 1.3 1 0 0 1 1 1 1 LSM domain Ycf4 PF02392.11 EKE42108.1 - 0.0052 16.1 1.0 0.0064 15.8 0.0 1.7 2 0 0 2 2 2 1 Ycf4 EF-hand_1 PF00036.27 EKE42110.1 - 2.1e-17 60.9 1.1 8.5e-05 21.5 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EKE42110.1 - 2.4e-12 46.8 1.0 2.2e-06 27.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE42110.1 - 3.9e-11 41.8 2.0 0.00039 20.0 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EKE42110.1 - 6.7e-09 34.6 0.7 0.0079 15.4 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EKE42110.1 - 2e-08 33.7 4.6 5.7e-05 22.6 0.1 4.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.2 EKE42110.1 - 0.0011 18.6 0.8 0.14 11.9 0.2 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EKE42110.1 - 0.18 11.5 1.2 1.7 8.3 0.1 2.8 3 0 0 3 3 3 0 EF hand Ras PF00071.17 EKE42111.1 - 4.8e-34 117.0 0.5 5.5e-34 116.8 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42111.1 - 1.9e-12 47.7 0.0 2.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE42111.1 - 5.1e-10 39.0 0.1 2.6e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EKE42111.1 - 2.3e-07 30.2 0.1 2.7e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EKE42111.1 - 0.00024 20.4 1.5 0.032 13.4 0.3 2.9 2 1 1 3 3 3 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EKE42111.1 - 0.00095 19.1 0.1 0.0014 18.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EKE42111.1 - 0.0077 15.9 0.9 0.16 11.6 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EKE42111.1 - 0.0094 16.0 0.0 0.013 15.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain TLD PF07534.11 EKE42112.1 - 2.6e-08 33.9 2.2 4.2e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 TLD ATG_C PF09333.6 EKE42113.1 - 0.0049 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain NIF PF03031.13 EKE42114.1 - 5.4e-14 52.1 1.1 1.6e-13 50.5 0.8 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DEAD PF00270.24 EKE42116.1 - 4.4e-26 91.3 0.8 9.4e-26 90.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE42116.1 - 7.1e-20 70.6 0.5 1.6e-19 69.4 0.2 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKE42116.1 - 0.00011 22.1 0.4 0.00069 19.4 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit MutL PF13941.1 EKE42116.1 - 0.00024 19.5 0.5 0.00038 18.9 0.3 1.2 1 0 0 1 1 1 1 MutL protein AAA_22 PF13401.1 EKE42116.1 - 0.0086 16.2 0.6 0.067 13.3 0.0 2.5 2 1 1 3 3 3 1 AAA domain Mito_carr PF00153.22 EKE42118.1 - 4.9e-56 186.4 5.7 3.2e-19 68.4 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein TMEM141 PF15110.1 EKE42118.1 - 0.048 13.9 0.6 11 6.3 0.0 2.6 2 0 0 2 2 2 0 TMEM141 protein family NDUF_B12 PF08122.7 EKE42118.1 - 0.57 9.9 3.3 0.64 9.7 0.8 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family PI3Ka PF00613.15 EKE42120.1 - 1.9e-51 173.8 3.3 2.5e-51 173.5 1.3 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EKE42120.1 - 6.4e-41 140.3 0.1 2.1e-40 138.6 0.1 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EKE42120.1 - 2.1e-13 50.2 0.0 4.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 EKE42120.1 - 2.4e-13 49.9 0.2 1.5e-12 47.3 0.1 2.5 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain WD40 PF00400.27 EKE42121.1 - 5.4e-27 92.6 1.1 1.3e-07 31.2 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat SGL PF08450.7 EKE42121.1 - 0.00065 19.1 0.1 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region BBS2_Mid PF14783.1 EKE42121.1 - 0.00077 19.2 3.6 0.033 13.9 0.0 4.0 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region VID27 PF08553.5 EKE42121.1 - 0.0021 16.3 5.9 0.068 11.3 3.2 2.1 1 1 1 2 2 2 2 VID27 cytoplasmic protein Cytochrom_D1 PF02239.11 EKE42121.1 - 0.0049 15.2 0.1 0.33 9.2 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain TFIIIC_delta PF12657.2 EKE42121.1 - 0.11 12.2 0.9 3.9 7.1 0.0 3.0 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DivIVA PF05103.8 EKE42121.1 - 0.23 11.5 5.3 0.34 10.9 3.4 1.5 1 1 0 1 1 1 0 DivIVA protein vATP-synt_E PF01991.13 EKE42121.1 - 0.3 10.3 5.6 0.63 9.2 3.9 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit TPR_11 PF13414.1 EKE42122.1 - 8.1e-19 67.0 4.6 1.3e-08 34.3 0.0 2.5 1 1 2 3 3 3 3 TPR repeat FKBP_C PF00254.23 EKE42122.1 - 7.4e-16 57.9 0.1 2.3e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.23 EKE42122.1 - 3.4e-10 39.0 5.9 6.4e-08 31.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKE42122.1 - 3e-09 36.1 6.1 8.5e-07 28.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE42122.1 - 1.9e-08 33.4 0.6 2.5e-07 29.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKE42122.1 - 2.8e-06 27.4 0.2 0.00065 20.1 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKE42122.1 - 1.7e-05 24.6 2.9 0.0036 17.1 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKE42122.1 - 2.6e-05 24.4 1.0 0.0001 22.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKE42122.1 - 0.00013 22.5 2.3 0.0054 17.3 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKE42122.1 - 0.00085 19.6 0.1 0.0047 17.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKE42122.1 - 0.0062 16.2 0.3 3 7.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKE42122.1 - 0.012 15.7 1.0 0.15 12.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EKE42122.1 - 0.035 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EKE42122.1 - 0.036 14.1 0.8 0.24 11.5 0.6 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat U79_P34 PF03064.11 EKE42122.1 - 0.087 12.3 15.5 0.17 11.3 10.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RRM_6 PF14259.1 EKE42123.1 - 0.00059 19.7 0.1 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IL1 PF00340.14 EKE42123.1 - 0.0035 16.7 0.3 0.0056 16.1 0.2 1.3 1 0 0 1 1 1 1 Interleukin-1 / 18 RRM_1 PF00076.17 EKE42123.1 - 0.0038 16.8 0.3 0.0085 15.7 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATG19_autophagy PF12744.2 EKE42123.1 - 0.0086 15.3 0.3 0.0095 15.2 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding Pkinase PF00069.20 EKE42124.1 - 2.5e-52 177.6 0.0 7e-52 176.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42124.1 - 2.5e-21 75.9 0.1 5e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 EKE42124.1 - 0.001 18.7 0.4 0.001 18.7 0.3 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKE42124.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKE42124.1 - 0.0074 15.6 0.0 0.0074 15.6 0.0 2.8 3 0 0 3 3 3 1 RIO1 family Kinase-like PF14531.1 EKE42124.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FcoT PF10862.3 EKE42124.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 FcoT-like thioesterase domain Kdo PF06293.9 EKE42124.1 - 0.022 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.11 EKE42124.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC1 family DUF4502 PF14950.1 EKE42126.1 - 0.00019 20.7 0.3 0.00025 20.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) KdpD PF02702.12 EKE42126.1 - 0.046 12.8 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain DENN PF02141.16 EKE42127.1 - 4.5e-31 108.0 0.4 7.6e-31 107.2 0.3 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EKE42127.1 - 9.9e-11 41.4 0.3 3.3e-10 39.7 0.2 1.9 1 0 0 1 1 1 1 uDENN domain LIM PF00412.17 EKE42127.1 - 0.00058 19.8 18.5 0.0022 18.0 12.8 2.1 1 0 0 1 1 1 1 LIM domain dDENN PF03455.14 EKE42127.1 - 0.00086 19.3 9.1 0.0018 18.2 6.3 1.6 1 0 0 1 1 1 1 dDENN domain AMP-binding PF00501.23 EKE42128.1 - 8.6e-73 245.0 0.0 1.2e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKE42128.1 - 5.6e-45 153.2 0.0 9.6e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 EKE42128.1 - 1.3e-14 54.9 0.1 1e-13 52.0 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EKE42128.1 - 5.8e-14 52.1 0.0 3.1e-13 49.7 0.0 2.2 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKE42128.1 - 1.7e-11 43.3 0.0 2.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EKE42128.1 - 7.8e-08 32.4 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EKE42128.1 - 1.6e-05 23.9 0.0 5.1e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EKE42128.1 - 0.046 13.7 0.0 0.83 9.6 0.0 2.6 2 1 0 2 2 2 0 NADH(P)-binding NmrA PF05368.8 EKE42128.1 - 0.06 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family DUF677 PF05055.7 EKE42129.1 - 0.0047 15.6 7.4 0.0047 15.6 5.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF677) UPF0184 PF03670.8 EKE42129.1 - 0.055 13.6 4.4 0.082 13.0 0.9 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Borrelia_P83 PF05262.6 EKE42129.1 - 0.32 9.2 26.7 0.43 8.8 18.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hemerythrin PF01814.18 EKE42129.1 - 0.95 9.6 8.8 0.92 9.6 0.5 2.8 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Lge1 PF11488.3 EKE42129.1 - 1.7 8.9 10.2 0.2 11.8 1.7 3.0 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 RhoGEF PF00621.15 EKE42131.1 - 5.9e-38 130.5 3.7 5.9e-38 130.5 2.6 2.2 2 1 0 2 2 2 1 RhoGEF domain zf-piccolo PF05715.8 EKE42131.1 - 0.0059 16.5 12.2 0.0064 16.4 5.8 2.6 2 0 0 2 2 2 1 Piccolo Zn-finger FYVE PF01363.16 EKE42131.1 - 0.21 11.5 8.8 0.58 10.0 6.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.5 EKE42131.1 - 3.1 7.8 9.2 1.5 8.7 2.6 2.7 1 1 1 2 2 2 0 Zinc ribbon domain FYVE_2 PF02318.11 EKE42131.1 - 8.8 6.2 17.0 0.6 10.0 6.9 2.5 2 1 1 3 3 3 0 FYVE-type zinc finger BAR PF03114.13 EKE42132.1 - 9.8e-16 57.9 12.4 1.5e-15 57.3 8.6 1.4 1 1 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EKE42132.1 - 1.4e-14 53.3 0.7 3.1e-14 52.2 0.5 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE42132.1 - 1.5e-12 46.8 0.1 2.7e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKE42132.1 - 1.9e-12 46.3 0.6 3.5e-12 45.5 0.4 1.5 1 0 0 1 1 1 1 SH3 domain DUF4220 PF13968.1 EKE42132.1 - 0.21 10.6 2.0 0.32 10.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Peptidase_C48 PF02902.14 EKE42133.1 - 2.4e-21 76.3 0.0 4.8e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MORN_2 PF07661.8 EKE42134.1 - 0.06 13.3 2.5 17 5.8 0.1 3.4 3 0 0 3 3 3 0 MORN repeat variant RabGAP-TBC PF00566.13 EKE42135.1 - 8.9e-25 87.4 0.6 1.4e-24 86.8 0.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PIG-L PF02585.12 EKE42136.1 - 4.4e-16 59.5 0.0 1.5e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF468 PF04318.7 EKE42136.1 - 0.44 11.1 5.0 6.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF468) UDP-g_GGTase PF06427.6 EKE42137.1 - 2.9e-10 39.8 2.0 6.1e-10 38.7 1.4 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase DUF4314 PF14192.1 EKE42139.1 - 0.14 12.4 0.2 0.74 10.1 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4314) DUF2435 PF10363.4 EKE42140.1 - 0.2 11.5 1.7 0.37 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) His_Phos_2 PF00328.17 EKE42141.1 - 3.1e-33 115.5 0.2 3.1e-33 115.5 0.1 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Syntaxin-6_N PF09177.6 EKE42142.1 - 0.013 15.8 15.4 0.03 14.7 4.3 2.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SPOC PF07744.8 EKE42142.1 - 0.03 14.8 1.3 0.041 14.3 0.1 2.0 2 0 0 2 2 2 0 SPOC domain Spc7 PF08317.6 EKE42142.1 - 0.085 11.5 30.3 0.088 11.4 15.0 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 EKE42142.1 - 0.23 11.3 29.8 0.88 9.4 13.0 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EKE42142.1 - 0.25 11.1 27.1 0.17 11.7 9.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EKE42142.1 - 0.73 9.6 23.2 1.9 8.2 6.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EKE42142.1 - 0.83 8.7 3.5 5.8 6.0 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein YjcZ PF13990.1 EKE42142.1 - 1.3 8.0 7.3 1.1 8.3 4.0 1.5 1 1 0 1 1 1 0 YjcZ-like protein CHASE3 PF05227.8 EKE42142.1 - 1.5 8.5 10.6 2.1 8.0 0.7 2.8 1 1 0 2 2 2 0 CHASE3 domain NPV_P10 PF05531.7 EKE42142.1 - 1.6 9.0 11.4 5.5 7.3 0.6 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EKE42142.1 - 4.1 6.9 35.8 0.058 12.9 13.5 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 EKE42142.1 - 4.8 7.1 16.2 0.079 12.8 1.0 3.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Cupin_4 PF08007.7 EKE42142.1 - 5.5 6.1 8.6 2.9 7.0 0.0 3.0 2 1 1 3 3 3 0 Cupin superfamily protein DASH_Dad3 PF08656.5 EKE42142.1 - 7.4 6.3 12.6 1.9 8.2 1.3 3.3 1 1 2 3 3 3 0 DASH complex subunit Dad3 RasGAP PF00616.14 EKE42143.1 - 1.8e-39 135.4 4.9 3.8e-39 134.3 3.4 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EKE42143.1 - 5.7e-06 26.2 0.4 1.7e-05 24.8 0.3 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Myosin_TH1 PF06017.8 EKE42143.1 - 0.0017 17.7 0.1 0.0041 16.4 0.1 1.6 1 0 0 1 1 1 1 Myosin tail MerR-DNA-bind PF09278.6 EKE42144.1 - 0.13 12.7 5.6 0.29 11.5 3.9 1.7 1 0 0 1 1 1 0 MerR, DNA binding Vps51 PF08700.6 EKE42144.1 - 0.51 10.2 7.5 0.31 10.8 3.8 1.8 2 1 0 2 2 2 0 Vps51/Vps67 Atg14 PF10186.4 EKE42144.1 - 0.79 8.6 11.3 0.88 8.4 7.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Asp-B-Hydro_N PF05279.6 EKE42144.1 - 0.85 9.4 13.1 1 9.1 9.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2252 PF10009.4 EKE42144.1 - 0.86 8.4 4.0 0.89 8.3 2.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4407 PF14362.1 EKE42144.1 - 0.93 8.3 4.4 1.1 8.1 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_N PF09440.5 EKE42144.1 - 1.2 9.2 9.2 2 8.5 6.2 1.6 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain Tho2 PF11262.3 EKE42144.1 - 2.1 7.2 7.4 3.2 6.6 5.2 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 OmpH PF03938.9 EKE42144.1 - 2.4 8.0 9.9 3.8 7.4 6.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PhoU PF01895.14 EKE42144.1 - 7.8 7.0 16.2 8.7 6.8 7.3 2.8 1 1 1 2 2 2 0 PhoU domain DivIC PF04977.10 EKE42144.1 - 9 5.8 12.7 1.9 8.0 5.4 2.3 1 1 2 3 3 3 0 Septum formation initiator SapB_2 PF03489.12 EKE42145.1 - 2.7e-09 36.8 0.6 6.6e-09 35.6 0.4 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EKE42145.1 - 0.0004 20.1 0.4 0.0035 17.1 0.0 2.3 2 1 1 3 3 3 1 Saposin-like type B, region 1 TRAM_LAG1_CLN8 PF03798.11 EKE42146.1 - 7.5e-30 103.9 18.4 1.2e-29 103.3 12.7 1.3 1 0 0 1 1 1 1 TLC domain WD40 PF00400.27 EKE42147.1 - 1.5e-06 27.8 4.1 0.58 10.1 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Abi PF02517.11 EKE42149.1 - 2.5e-17 62.8 4.6 2.5e-17 62.8 3.2 2.9 1 1 1 2 2 2 1 CAAX protease self-immunity 7TMR-DISM_7TM PF07695.6 EKE42149.1 - 0.16 11.6 32.6 1.7 8.2 10.8 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Yip1 PF04893.12 EKE42149.1 - 0.19 11.2 24.5 0.59 9.6 8.7 2.8 1 1 1 2 2 2 0 Yip1 domain Brevenin PF03032.10 EKE42149.1 - 0.32 10.8 0.8 1 9.2 0.0 2.0 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family DUF1772 PF08592.6 EKE42149.1 - 6.7 6.4 8.7 0.7 9.6 1.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Rad60-SLD PF11976.3 EKE42150.1 - 2e-18 65.8 2.8 6.3e-10 38.6 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EKE42150.1 - 7.2e-10 38.1 1.7 0.0011 18.2 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin family Ras PF00071.17 EKE42151.1 - 5e-46 156.0 1.7 6e-46 155.7 1.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42151.1 - 5.4e-18 65.6 0.1 8.4e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42151.1 - 2.9e-14 52.7 0.5 3.4e-14 52.4 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE42151.1 - 1.4e-08 34.1 0.6 1.7e-08 33.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE42151.1 - 5.1e-06 26.0 0.1 0.00011 21.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE42151.1 - 6.7e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKE42151.1 - 0.0095 15.1 0.1 0.013 14.6 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKE42151.1 - 0.016 14.7 0.2 0.086 12.3 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 EKE42151.1 - 0.017 13.8 1.4 0.036 12.7 0.3 1.9 1 1 1 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.18 EKE42151.1 - 0.056 13.2 0.3 0.42 10.4 0.0 2.2 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 EKE42151.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 EKE42151.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 EKE42151.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RP-C_C PF11800.3 EKE42153.1 - 4.1 7.0 10.0 8.6 5.9 6.9 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Spt5-NGN PF03439.8 EKE42154.1 - 9.8e-16 57.2 0.1 2.4e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EKE42154.1 - 8e-13 47.5 24.6 0.0055 16.3 0.1 6.0 6 0 0 6 6 6 4 KOW motif FTR_C PF02741.10 EKE42154.1 - 0.027 14.2 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 FTR, proximal lobe Peptidase_S24 PF00717.18 EKE42154.1 - 0.68 9.6 7.0 7.4 6.2 0.3 3.4 3 0 0 3 3 3 0 Peptidase S24-like Rep_fac-A_3 PF08661.6 EKE42155.1 - 0.00048 19.9 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 Isy1 PF06246.7 EKE42156.1 - 1e-37 129.9 14.2 2e-37 129.0 9.9 1.4 1 1 0 1 1 1 1 Isy1-like splicing family PQ-loop PF04193.9 EKE42157.1 - 2.6e-17 62.1 12.7 1.3e-10 40.6 0.8 3.8 4 0 0 4 4 4 2 PQ loop repeat DUF4418 PF14387.1 EKE42157.1 - 0.15 11.7 0.1 0.15 11.7 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4418) GNVR PF13807.1 EKE42157.1 - 0.22 11.3 0.2 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF3624 PF12292.3 EKE42157.1 - 4.8 7.6 15.4 6.6 7.2 3.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3624) MgsA_C PF12002.3 EKE42158.1 - 5.6e-30 104.2 0.0 8.5e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EKE42158.1 - 6.1e-15 55.5 0.8 2.5e-14 53.6 0.1 2.3 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKE42158.1 - 3.9e-14 52.2 0.1 1.5e-11 43.7 0.0 2.2 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EKE42158.1 - 1e-07 31.8 0.3 2.7e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE42158.1 - 7.1e-07 30.0 0.0 1.7e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKE42158.1 - 9e-07 28.7 0.0 6.4e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKE42158.1 - 6.9e-06 26.2 3.1 0.00049 20.2 2.1 3.1 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EKE42158.1 - 1.6e-05 24.4 0.0 0.00028 20.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 EKE42158.1 - 6.3e-05 23.0 0.0 0.34 10.8 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain Viral_helicase1 PF01443.13 EKE42158.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EKE42158.1 - 0.0003 19.6 2.1 0.04 12.6 0.0 2.6 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EKE42158.1 - 0.00038 20.5 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EKE42158.1 - 0.00052 20.3 0.9 0.0022 18.2 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKE42158.1 - 0.00058 19.8 0.6 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 EKE42158.1 - 0.0007 19.9 0.1 0.0018 18.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.12 EKE42158.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Thymidylate kinase Mg_chelatase PF01078.16 EKE42158.1 - 0.0012 18.0 0.0 0.023 13.8 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EKE42158.1 - 0.0026 16.8 0.0 0.0049 15.9 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin G-alpha PF00503.15 EKE42158.1 - 0.0027 16.4 0.1 0.0033 16.1 0.1 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_10 PF12846.2 EKE42158.1 - 0.0031 16.9 0.2 0.38 10.1 0.0 2.7 2 1 1 3 3 3 1 AAA-like domain AAA_33 PF13671.1 EKE42158.1 - 0.0057 16.5 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EKE42158.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EKE42158.1 - 0.0077 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EKE42158.1 - 0.012 15.2 0.2 0.29 10.8 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 EKE42158.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EKE42158.1 - 0.022 14.3 0.0 0.073 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EKE42158.1 - 0.024 14.1 0.0 0.36 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKE42158.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ADK PF00406.17 EKE42158.1 - 0.055 13.3 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 1 0 Adenylate kinase AAA_19 PF13245.1 EKE42158.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 EKE42158.1 - 0.065 13.1 6.6 0.24 11.3 2.6 2.9 2 1 0 2 2 2 0 AAA domain RNA_pol_Rpb2_6 PF00562.23 EKE42160.1 - 1.2e-124 416.0 0.0 2.2e-124 415.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EKE42160.1 - 7.9e-52 175.1 1.5 7.9e-52 175.1 1.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EKE42160.1 - 1.8e-28 98.5 0.1 5.6e-28 97.0 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EKE42160.1 - 6.6e-22 77.0 0.1 1.6e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 EKE42160.1 - 1.9e-21 76.3 2.3 1.9e-21 76.3 1.6 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EKE42160.1 - 1e-19 70.0 0.8 6e-19 67.5 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EKE42160.1 - 4.6e-11 42.4 2.9 4.6e-11 42.4 2.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 V_ATPase_I PF01496.14 EKE42161.1 - 9.1e-181 602.4 15.6 2.5e-180 601.0 10.8 1.6 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Nup35_RRM PF05172.8 EKE42161.1 - 0.073 12.8 0.4 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3070 PF11270.3 EKE42162.1 - 0.06 13.1 0.3 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) PP2C PF00481.16 EKE42163.1 - 2e-57 194.5 0.0 2.5e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE42163.1 - 0.0015 18.2 0.0 0.043 13.5 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EKE42163.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Ras PF00071.17 EKE42164.1 - 4.8e-62 208.1 0.6 5.7e-62 207.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42164.1 - 8.5e-18 64.9 0.1 2.2e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE42164.1 - 2.2e-16 59.5 0.1 2.9e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE42164.1 - 3.4e-07 30.2 0.0 4.9e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE42164.1 - 6.2e-05 22.5 0.1 0.0001 21.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE42164.1 - 6.9e-05 22.0 0.0 9.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKE42164.1 - 0.0029 17.7 0.0 0.0056 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKE42164.1 - 0.003 17.2 0.1 0.0049 16.6 0.1 1.5 1 1 0 1 1 1 1 Archaeal ATPase SRPRB PF09439.5 EKE42164.1 - 0.0037 16.5 0.0 0.0052 16.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EKE42164.1 - 0.0037 17.5 0.1 0.0087 16.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_15 PF13175.1 EKE42164.1 - 0.0051 15.9 0.1 0.0091 15.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EKE42164.1 - 0.0066 15.6 0.1 0.0088 15.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EKE42164.1 - 0.017 14.6 0.0 0.16 11.4 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EKE42164.1 - 0.031 14.2 0.2 2.2 8.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKE42164.1 - 0.043 13.7 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKE42164.1 - 0.052 13.2 0.0 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKE42164.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain RNA_pol_Rpb4 PF03874.11 EKE42165.1 - 3.3e-09 36.7 0.4 3.6e-08 33.4 0.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF3847 PF12958.2 EKE42165.1 - 0.03 14.0 0.5 0.66 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) LEM PF03020.10 EKE42165.1 - 1.5 8.3 5.9 7.4 6.1 0.6 2.9 3 0 0 3 3 3 0 LEM domain Pkinase_Tyr PF07714.12 EKE42166.1 - 5.9e-40 136.9 0.0 9.9e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE42166.1 - 3.3e-31 108.3 0.0 1.1e-30 106.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.2 EKE42166.1 - 6.4e-13 47.9 51.9 4.5e-07 29.3 2.0 7.2 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE42166.1 - 7.6e-12 44.8 38.3 1.4e-07 31.1 3.7 5.6 3 1 0 4 4 4 2 Leucine rich repeat Myotub-related PF06602.9 EKE42166.1 - 5.8e-10 38.4 9.0 1.8e-09 36.8 6.1 1.8 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain LRR_1 PF00560.28 EKE42166.1 - 3.4e-05 23.2 36.7 0.4 10.9 0.2 10.5 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_5 PF13306.1 EKE42167.1 - 1.4e-48 163.8 29.5 4.5e-29 100.7 8.6 3.5 3 1 1 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42167.1 - 2.7e-15 55.8 15.9 2.7e-06 27.0 1.3 6.1 2 2 4 6 6 6 5 Leucine rich repeat Gemini_AL3 PF01407.12 EKE42167.1 - 0.00062 19.2 0.4 0.18 11.2 0.0 2.5 2 0 0 2 2 2 2 Geminivirus AL3 protein Eclosion PF04736.7 EKE42167.1 - 0.014 14.8 0.6 0.051 13.0 0.4 2.0 1 0 0 1 1 1 0 Eclosion hormone ADH_zinc_N PF00107.21 EKE42168.1 - 1.7e-18 66.3 0.1 2.9e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKE42168.1 - 6.9e-15 54.7 0.1 6.9e-15 54.7 0.1 1.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Hexapep PF00132.19 EKE42171.1 - 2.3e-20 71.0 12.6 1.8e-10 39.7 0.3 4.6 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKE42171.1 - 7.4e-09 35.0 10.3 0.00071 19.0 1.4 3.6 3 1 2 5 5 5 3 Hexapeptide repeat of succinyl-transferase MalM PF07148.7 EKE42171.1 - 0.0081 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Maltose operon periplasmic protein precursor (MalM) Cactin_mid PF10312.4 EKE42171.1 - 0.074 12.3 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Conserved mid region of cactin Fucokinase PF07959.7 EKE42171.1 - 0.31 9.5 2.8 0.61 8.5 1.9 1.5 1 1 0 1 1 1 0 L-fucokinase Cpn10 PF00166.16 EKE42171.1 - 0.91 9.5 3.7 5.9 6.9 0.0 2.7 2 1 1 3 3 3 0 Chaperonin 10 Kd subunit DUF1767 PF08585.7 EKE42172.1 - 0.0072 16.5 0.1 0.01 16.0 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1767) Drf_FH3 PF06367.11 EKE42172.1 - 0.011 15.1 0.1 0.037 13.4 0.1 1.7 1 1 0 1 1 1 0 Diaphanous FH3 Domain Pou PF00157.12 EKE42172.1 - 0.043 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Glyco_hydro_20 PF00728.17 EKE42173.1 - 1.3e-81 274.4 0.5 1.8e-81 274.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EKE42173.1 - 6.1e-14 52.7 0.5 1.6e-13 51.4 0.1 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EKE42173.1 - 1.1e-06 29.1 0.0 3.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RasGAP PF00616.14 EKE42174.1 - 9.1e-06 25.4 13.5 0.0011 18.6 0.8 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Fez1 PF06818.10 EKE42174.1 - 0.22 11.5 3.8 0.13 12.2 0.9 1.8 2 0 0 2 2 2 0 Fez1 FANCI_S2 PF14676.1 EKE42174.1 - 1.1 9.1 7.5 0.43 10.4 0.6 2.9 2 1 1 3 3 3 0 FANCI solenoid 2 MerR-DNA-bind PF09278.6 EKE42176.1 - 0.017 15.4 0.4 0.037 14.4 0.3 1.4 1 0 0 1 1 1 0 MerR, DNA binding DUF655 PF04919.7 EKE42176.1 - 0.031 13.9 1.5 0.046 13.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) TrkH PF02386.11 EKE42177.1 - 2.4e-44 151.3 34.3 5.7e-43 146.8 18.5 2.3 2 1 0 2 2 2 2 Cation transport protein Hydrolase_3 PF08282.7 EKE42178.1 - 6.3e-57 193.0 7.1 7.1e-57 192.8 4.9 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EKE42178.1 - 1.3e-11 44.3 0.0 0.00012 21.4 0.0 2.4 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EKE42178.1 - 4.4e-09 36.7 2.6 2.2e-07 31.2 0.1 3.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EKE42178.1 - 3.9e-06 25.9 0.2 0.003 16.4 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase PF00702.21 EKE42178.1 - 7.5e-06 26.5 11.0 0.0037 17.7 3.4 3.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase UPF0086 PF01868.11 EKE42178.1 - 0.056 13.0 0.1 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function UPF0086 FdhD-NarQ PF02634.10 EKE42178.1 - 0.057 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 FdhD/NarQ family IF2_N PF04760.10 EKE42178.1 - 0.12 12.0 2.7 0.36 10.5 0.0 2.9 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Vps35 PF03635.12 EKE42179.1 - 3.2e-131 438.9 26.1 7.1e-131 437.8 18.1 1.5 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 SSP160 PF06933.6 EKE42179.1 - 0.28 9.1 0.7 0.49 8.3 0.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Prefoldin_2 PF01920.15 EKE42181.1 - 1.1e-11 44.3 15.1 1.4e-11 44.1 10.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EKE42181.1 - 0.037 13.6 10.5 0.07 12.7 7.3 1.6 1 1 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 EKE42181.1 - 0.4 10.1 12.5 1.9 8.0 2.7 2.3 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 EKE42181.1 - 0.45 10.7 3.8 2 8.7 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 EKE42181.1 - 0.48 10.0 5.6 1.7 8.2 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.6 EKE42181.1 - 0.85 9.5 7.6 4.4 7.2 0.1 2.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 EKE42181.1 - 0.85 7.9 7.6 1 7.7 5.2 1.0 1 0 0 1 1 1 0 AAA domain Sugarporin_N PF11471.3 EKE42181.1 - 1.4 8.5 13.5 0.063 12.9 2.2 3.3 3 1 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF2680 PF10925.3 EKE42181.1 - 7.6 6.4 9.6 20 5.1 1.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2680) Ribosomal_S17 PF00366.15 EKE42182.1 - 5.8e-27 93.5 1.8 1e-26 92.7 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Cass2 PF14526.1 EKE42183.1 - 0.011 15.7 0.3 0.011 15.7 0.2 2.4 1 1 0 2 2 2 0 Integron-associated effector binding protein DUF3635 PF12330.3 EKE42183.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF3635) Fumble PF03630.9 EKE42183.1 - 1.4 7.7 10.3 2.4 6.9 7.1 1.5 1 1 0 1 1 1 0 Fumble DUF3573 PF12097.3 EKE42183.1 - 2.8 6.4 8.6 3.5 6.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APG6 PF04111.7 EKE42183.1 - 7.5 5.5 28.3 5.2 6.0 12.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Syntaxin PF00804.20 EKE42184.1 - 0.028 14.5 2.7 0.083 13.0 1.9 1.8 1 0 0 1 1 1 0 Syntaxin DUF349 PF03993.7 EKE42185.1 - 0.056 13.6 10.6 0.56 10.4 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Cluap1 PF10234.4 EKE42185.1 - 0.7 9.0 14.9 0.92 8.6 10.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Uso1_p115_C PF04871.8 EKE42185.1 - 0.78 9.6 9.7 0.22 11.4 4.3 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_23 PF13476.1 EKE42185.1 - 1.4 9.1 17.8 2.1 8.6 12.3 1.3 1 0 0 1 1 1 0 AAA domain YgaB PF14182.1 EKE42185.1 - 3.9 7.7 14.3 0.26 11.5 5.2 2.4 2 1 0 2 2 2 0 YgaB-like protein ABC_tran_2 PF12848.2 EKE42185.1 - 4.4 7.2 15.8 1.8 8.4 7.4 2.3 2 1 1 3 3 3 0 ABC transporter IncA PF04156.9 EKE42187.1 - 0.038 13.5 0.1 0.038 13.5 0.0 2.3 2 1 1 3 3 3 0 IncA protein DUF2631 PF10939.3 EKE42187.1 - 0.97 9.3 7.4 0.1 12.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) COPI_assoc PF08507.5 EKE42187.1 - 3.5 7.2 16.4 13 5.4 11.4 2.1 1 1 0 1 1 1 0 COPI associated protein Actin PF00022.14 EKE42189.1 - 7.1e-73 245.2 0.0 1e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 Actin LRR_5 PF13306.1 EKE42190.1 - 3.8e-158 518.1 121.9 3.2e-35 120.6 6.9 6.9 1 1 5 7 7 7 7 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42190.1 - 5.5e-52 173.3 71.0 2.3e-08 33.6 0.9 13.1 3 3 11 14 14 14 14 Leucine rich repeat DUF1699 PF08004.6 EKE42190.1 - 4.8 6.7 7.0 21 4.6 0.1 5.0 5 1 0 6 6 6 0 Protein of unknown function (DUF1699) ESCRT-II PF05871.7 EKE42191.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit ABC2_membrane_6 PF06182.6 EKE42192.1 - 0.0066 16.0 3.3 0.0089 15.5 2.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1230 PF06799.6 EKE42192.1 - 0.073 12.9 0.8 0.088 12.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) Pox_A14 PF05767.7 EKE42192.1 - 0.3 11.0 3.1 0.43 10.5 2.1 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Actin PF00022.14 EKE42193.1 - 1.4e-72 244.2 0.0 1.7e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Actin DUF327 PF03885.8 EKE42195.1 - 0.033 14.0 1.3 0.048 13.4 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF327) DUF16 PF01519.11 EKE42195.1 - 0.036 14.2 4.9 0.043 14.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.1 EKE42195.1 - 0.044 12.7 3.0 0.048 12.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) THOC7 PF05615.8 EKE42195.1 - 0.046 14.0 7.8 0.052 13.8 5.4 1.0 1 0 0 1 1 1 0 Tho complex subunit 7 TcdA_TcdB_pore PF12920.2 EKE42195.1 - 0.061 11.2 1.4 0.066 11.1 1.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF1572 PF07609.6 EKE42195.1 - 0.077 12.5 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) Shugoshin_N PF07558.6 EKE42195.1 - 0.095 12.4 0.7 0.095 12.4 0.5 1.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region YlqD PF11068.3 EKE42195.1 - 0.12 12.4 7.5 0.16 12.0 5.2 1.2 1 0 0 1 1 1 0 YlqD protein DUF2317 PF10079.4 EKE42195.1 - 0.27 9.7 4.7 0.26 9.8 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF2968 PF11180.3 EKE42195.1 - 0.35 10.2 6.5 0.36 10.1 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IncA PF04156.9 EKE42195.1 - 0.71 9.4 7.5 0.8 9.2 5.2 1.0 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EKE42195.1 - 0.91 8.5 7.9 0.98 8.4 5.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FKBP_C PF00254.23 EKE42196.1 - 1.6e-27 95.3 0.0 2.4e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PB1 PF00564.19 EKE42197.1 - 5.1e-09 35.6 1.0 1.3e-08 34.4 0.7 1.6 1 0 0 1 1 1 1 PB1 domain Uricase PF01014.13 EKE42197.1 - 0.083 12.9 0.1 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 Uricase Varsurf_PPLC PF03490.8 EKE42198.1 - 0.001 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.14 EKE42198.1 - 0.01 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain IF4E PF01652.13 EKE42199.1 - 1.5e-10 40.8 0.2 1.5e-10 40.8 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E HSP90 PF00183.13 EKE42200.1 - 6.9e-258 856.3 40.9 9.2e-258 855.9 28.4 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EKE42200.1 - 7.5e-13 48.3 0.4 7.5e-13 48.3 0.3 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKE42200.1 - 1.4e-10 40.8 0.1 3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 EKE42200.1 - 0.19 11.0 28.9 0.027 13.8 12.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CENP-B_dimeris PF09026.5 EKE42200.1 - 8.7 6.6 14.6 28 5.0 0.3 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1913 PF08931.5 EKE42201.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1913) ABC2_membrane PF01061.19 EKE42202.1 - 2.2e-41 141.3 24.0 2.2e-41 141.3 16.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EKE42202.1 - 6.1e-27 94.5 0.3 1e-26 93.8 0.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKE42202.1 - 0.00042 20.3 9.2 0.0015 18.5 0.8 3.5 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EKE42202.1 - 0.00053 19.2 0.0 0.00096 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EKE42202.1 - 0.00065 19.1 0.4 0.0014 18.1 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EKE42202.1 - 0.0017 17.8 0.2 0.04 13.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKE42202.1 - 0.021 15.1 0.8 0.1 12.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EKE42202.1 - 0.046 13.6 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EKE42202.1 - 0.089 12.7 0.4 0.23 11.4 0.1 1.8 2 1 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 EKE42202.1 - 0.19 10.7 32.8 0.011 14.8 18.2 2.1 2 1 1 3 3 3 0 ABC-2 family transporter protein PAXIP1_C PF15364.1 EKE42203.1 - 0.11 12.4 2.5 0.12 12.3 1.7 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Synaptobrevin PF00957.16 EKE42204.1 - 2.1e-15 56.0 4.4 2.5e-15 55.8 3.0 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF2970 PF11174.3 EKE42204.1 - 0.049 13.2 3.1 0.071 12.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF3733 PF12534.3 EKE42204.1 - 0.065 12.5 0.5 0.092 12.0 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 GP41 PF00517.12 EKE42204.1 - 0.37 10.3 6.2 0.42 10.1 4.3 1.0 1 0 0 1 1 1 0 Retroviral envelope protein TMEM52 PF14979.1 EKE42204.1 - 0.39 10.6 2.7 0.5 10.2 1.9 1.2 1 0 0 1 1 1 0 Transmembrane 52 MMR_HSR1 PF01926.18 EKE42205.1 - 1.2e-17 63.8 0.0 2.8e-14 53.0 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE42205.1 - 5.8e-08 32.1 0.7 1.9e-07 30.4 0.1 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EKE42205.1 - 3.3e-06 26.3 0.0 6.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EKE42205.1 - 0.00079 18.9 1.5 0.95 8.8 0.0 3.8 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EKE42205.1 - 0.0086 15.9 0.3 0.0086 15.9 0.2 3.8 3 1 1 4 4 4 1 Dynamin family Miro PF08477.8 EKE42205.1 - 0.017 15.6 0.0 0.017 15.6 0.0 3.3 4 1 0 4 4 4 0 Miro-like protein AAA_22 PF13401.1 EKE42205.1 - 0.043 13.9 0.0 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain GST_C PF00043.20 EKE42205.1 - 0.34 10.9 2.6 2.5 8.1 0.0 3.3 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain YopE PF03545.8 EKE42206.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Helicase_C PF00271.26 EKE42207.1 - 7.5e-12 44.9 0.2 2.6e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE42207.1 - 8.8e-09 35.0 0.4 1.8e-08 34.0 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKE42207.1 - 4.6e-08 33.2 0.1 1.2e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain HA2 PF04408.18 EKE42207.1 - 7.5e-06 25.8 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_16 PF13191.1 EKE42207.1 - 0.00023 21.1 0.0 0.00068 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 EKE42207.1 - 0.00025 20.2 1.0 0.00045 19.3 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.1 EKE42207.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EKE42207.1 - 0.021 15.1 0.4 0.055 13.7 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_14 PF13173.1 EKE42207.1 - 0.021 14.7 0.0 0.13 12.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EKE42207.1 - 0.022 13.6 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 EKE42207.1 - 0.023 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EKE42207.1 - 0.033 13.6 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Helicase_RecD PF05127.9 EKE42207.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.1 EKE42207.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EKE42207.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EKE42207.1 - 0.15 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 EKE42207.1 - 0.22 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 EKE42208.1 - 2.2e-09 36.9 0.3 2.2e-09 36.9 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Amidase_6 PF12671.2 EKE42210.1 - 0.045 13.7 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 Putative amidase domain SPAN-X PF07458.7 EKE42210.1 - 0.051 13.7 1.3 0.12 12.6 0.8 1.6 1 1 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome DUF1175 PF06672.6 EKE42210.1 - 0.052 12.8 0.1 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) LRR_5 PF13306.1 EKE42211.1 - 1.6e-41 141.0 27.2 8.8e-26 90.1 9.4 2.9 2 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42211.1 - 4.5e-20 71.1 1.7 4.3e-07 29.5 0.0 4.4 3 2 2 5 5 5 4 Leucine rich repeat MIG-14_Wnt-bd PF06664.7 EKE42212.1 - 9.5e-44 149.4 29.3 1.2e-43 149.0 20.3 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Paramyxo_PCT PF14320.1 EKE42212.1 - 0.016 14.0 1.3 0.023 13.6 0.9 1.1 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered FA_desaturase PF00487.19 EKE42212.1 - 0.95 8.8 4.3 0.55 9.6 1.5 1.6 1 1 0 1 1 1 0 Fatty acid desaturase Tetraspannin PF00335.15 EKE42214.1 - 0.0012 18.2 9.6 0.0026 17.0 6.6 1.7 1 1 0 1 1 1 1 Tetraspanin family LMBR1 PF04791.11 EKE42214.1 - 0.006 15.2 0.8 0.008 14.8 0.2 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein 7tm_1 PF00001.16 EKE42214.1 - 0.011 14.9 1.2 0.018 14.1 0.8 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 EKE42214.1 - 0.026 13.6 4.2 0.034 13.2 2.5 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx UPF0542 PF15086.1 EKE42214.1 - 0.028 14.1 0.2 0.028 14.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 7TM_GPCR_Srv PF10323.4 EKE42214.1 - 0.028 13.5 0.7 0.047 12.8 0.4 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Mucin PF01456.12 EKE42214.1 - 0.11 12.3 1.4 0.21 11.3 1.0 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein 7TMR-DISM_7TM PF07695.6 EKE42214.1 - 5.3 6.6 13.3 0.96 9.0 6.6 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling Pescadillo_N PF06732.6 EKE42216.1 - 1.4e-77 260.7 8.5 1.4e-77 260.7 5.9 2.1 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EKE42216.1 - 2.8e-06 27.3 0.0 8e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain XPG_I PF00867.13 EKE42216.1 - 0.21 11.6 2.0 1.1 9.3 0.0 2.8 3 1 0 3 3 3 0 XPG I-region Ras PF00071.17 EKE42217.1 - 9.2e-27 93.4 0.0 1.4e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42217.1 - 6.6e-18 65.3 0.0 1.2e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42217.1 - 1.6e-06 27.4 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE42217.1 - 0.00089 18.4 0.1 0.002 17.3 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE42217.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE42217.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EKE42217.1 - 0.029 13.8 0.2 0.29 10.5 0.1 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EKE42217.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cauli_VI PF01693.11 EKE42218.1 - 3e-16 59.1 0.7 6e-16 58.1 0.5 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin PP2C PF00481.16 EKE42219.1 - 2.7e-56 190.8 0.0 3.7e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EKE42219.1 - 1.5e-25 88.3 53.8 1.2e-06 27.9 2.4 8.6 5 2 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE42219.1 - 1.1e-18 66.7 44.0 2.6e-07 30.2 3.4 7.1 5 2 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EKE42219.1 - 7.7e-16 55.6 55.1 0.023 14.6 0.6 13.7 12 1 1 13 13 13 8 Leucine Rich Repeat LRR_7 PF13504.1 EKE42219.1 - 6.4e-07 28.5 43.5 1.6 9.2 0.0 13.5 14 1 0 14 14 14 4 Leucine rich repeat PP2C_2 PF13672.1 EKE42219.1 - 0.00036 20.0 0.0 0.00097 18.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C ACDC PF14733.1 EKE42220.1 - 0.27 11.3 6.6 1.4 9.0 1.1 3.1 1 1 2 3 3 3 0 AP2-coincident C-terminal TFIID_20kDa PF03847.8 EKE42220.1 - 0.42 10.9 2.7 3 8.1 0.0 3.0 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A Xpo1 PF08389.7 EKE42220.1 - 0.65 9.9 4.8 4.5 7.1 0.1 2.9 2 1 1 3 3 3 0 Exportin 1-like protein TraT PF05818.7 EKE42221.1 - 0.016 14.6 0.1 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein 7TM_GPCR_Srz PF10325.4 EKE42222.1 - 0.12 11.4 3.8 0.15 11.1 2.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Fijivirus_P9-2 PF06837.6 EKE42222.1 - 0.15 11.1 2.6 0.17 10.9 1.8 1.0 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF3099 PF11298.3 EKE42222.1 - 0.25 11.1 1.5 11 5.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) FERM_M PF00373.13 EKE42223.1 - 2.2e-19 69.8 0.0 2.2e-19 69.8 0.0 4.2 4 1 0 4 4 4 1 FERM central domain I_LWEQ PF01608.12 EKE42223.1 - 1.7e-06 28.0 10.7 1.7e-06 28.0 7.4 6.3 3 2 2 6 6 6 1 I/LWEQ domain FERM_N PF09379.5 EKE42223.1 - 1.4e-05 25.0 4.6 0.00013 21.9 0.0 3.6 4 0 0 4 4 4 1 FERM N-terminal domain CactinC_cactus PF09732.4 EKE42224.1 - 1.1e-11 44.3 1.4 1.8e-11 43.7 1.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EKE42224.1 - 0.017 14.4 0.8 0.039 13.2 0.3 1.8 1 1 1 2 2 2 0 Conserved mid region of cactin ComC PF03047.9 EKE42224.1 - 0.065 12.6 0.2 0.18 11.2 0.1 1.8 1 0 0 1 1 1 0 COMC family Ribosomal_S13 PF00416.17 EKE42224.1 - 0.087 13.2 3.7 0.14 12.5 1.9 1.8 1 1 1 2 2 2 0 Ribosomal protein S13/S18 Phosducin PF02114.11 EKE42225.1 - 2.7e-13 49.2 4.3 2.6e-11 42.7 2.9 2.1 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EKE42225.1 - 0.023 14.3 0.1 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF3435 PF11917.3 EKE42225.1 - 0.055 12.1 2.9 0.067 11.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4187 PF13821.1 EKE42227.1 - 1.4e-08 34.1 1.9 4.3e-08 32.6 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EKE42227.1 - 2.3e-05 24.3 8.1 4.6e-05 23.3 5.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) RRM_5 PF13893.1 EKE42227.1 - 0.021 14.6 0.1 2 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EKE42227.1 - 3.9 7.2 5.6 7.6 6.2 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Autophagy_N PF03986.8 EKE42228.1 - 1.2e-31 109.4 0.3 2.1e-31 108.6 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EKE42228.1 - 1.4e-18 66.8 0.2 3.1e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EKE42228.1 - 5.5e-14 50.9 0.9 9e-14 50.2 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF1632 PF07857.7 EKE42229.1 - 2.3e-61 207.2 9.6 1.1e-41 142.7 4.4 2.6 2 1 1 3 3 3 2 CEO family (DUF1632) Sugar_transport PF06800.7 EKE42229.1 - 2e-08 33.6 18.4 2.1e-06 27.0 4.2 3.0 3 0 0 3 3 3 2 Sugar transport protein DUF1510 PF07423.6 EKE42229.1 - 0.031 13.6 7.1 0.047 13.0 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AIF-MLS PF14962.1 EKE42229.1 - 0.1 12.2 2.8 0.15 11.6 1.9 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Vfa1 PF08432.5 EKE42229.1 - 0.63 10.0 9.5 0.95 9.4 6.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2207 PF09972.4 EKE42229.1 - 2.4 6.6 11.6 0.16 10.5 0.4 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Coatomer_WDAD PF04053.9 EKE42230.1 - 7.5e-05 21.7 5.4 0.0064 15.3 0.2 2.7 2 0 0 2 2 2 2 Coatomer WD associated region Rsa3 PF14615.1 EKE42231.1 - 1.2e-16 59.6 0.3 2.2e-16 58.8 0.1 1.5 2 0 0 2 2 2 1 Ribosome-assembly protein 3 Nop16 PF09420.5 EKE42231.1 - 5.3 7.1 15.6 1e+02 2.9 10.8 2.5 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 Ras PF00071.17 EKE42234.1 - 5.6e-49 165.6 0.0 7.4e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42234.1 - 1.3e-13 51.5 0.0 2.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42234.1 - 3.6e-07 29.5 0.0 5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family EspA PF03433.8 EKE42234.1 - 0.00019 20.9 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 EspA-like secreted protein DUF3818 PF12825.2 EKE42234.1 - 0.13 10.8 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Snf7 PF03357.16 EKE42235.1 - 1.5e-26 92.8 17.4 1.5e-26 92.8 12.1 1.6 2 0 0 2 2 2 1 Snf7 MTBP_mid PF14919.1 EKE42235.1 - 0.4 9.2 5.4 0.55 8.8 3.7 1.4 1 0 0 1 1 1 0 MDM2-binding V_ATPase_I PF01496.14 EKE42235.1 - 0.43 8.3 9.1 0.55 8.0 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Val_tRNA-synt_C PF10458.4 EKE42235.1 - 2.1 8.5 6.9 68 3.6 3.1 3.5 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DivIVA PF05103.8 EKE42235.1 - 2.6 8.0 12.6 2.8 8.0 0.0 3.1 2 1 0 2 2 2 0 DivIVA protein tRNA-synt_2b PF00587.20 EKE42236.1 - 2.1e-19 69.7 0.0 3.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EKE42236.1 - 2.3e-19 69.0 5.1 1.1e-18 66.8 3.1 2.4 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EKE42236.1 - 6.7e-16 58.0 0.0 1.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DUF1654 PF07867.6 EKE42236.1 - 0.057 12.7 0.3 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DUF4174 PF13778.1 EKE42236.1 - 0.085 12.9 0.1 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) LisH PF08513.6 EKE42237.1 - 7.7e-05 22.3 0.0 0.00023 20.7 0.0 1.9 1 0 0 1 1 1 1 LisH PH PF00169.24 EKE42238.1 - 3.2e-13 49.7 0.3 5.4e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKE42238.1 - 0.0026 17.9 0.2 0.005 17.0 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3753 PF12575.3 EKE42238.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) zf-CCHC_3 PF13917.1 EKE42239.1 - 0.034 13.8 1.6 0.077 12.7 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EKE42239.1 - 0.057 13.1 1.1 0.14 11.8 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EKE42239.1 - 0.082 12.8 0.7 0.082 12.8 0.5 1.6 2 0 0 2 2 1 0 Zinc knuckle Slu7 PF11708.3 EKE42239.1 - 0.2 11.3 19.0 0.038 13.7 7.7 2.2 1 1 1 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DSPc PF00782.15 EKE42239.1 - 0.21 11.1 3.2 0.41 10.2 2.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain IncA PF04156.9 EKE42239.1 - 0.28 10.7 11.9 0.32 10.5 8.3 1.2 1 0 0 1 1 1 0 IncA protein DUF1465 PF07323.7 EKE42239.1 - 0.28 10.7 2.2 0.3 10.6 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) DUF3186 PF11382.3 EKE42239.1 - 0.39 9.8 3.3 0.68 9.0 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3186) DUF3450 PF11932.3 EKE42239.1 - 1.9 7.6 8.1 0.94 8.6 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.1 EKE42239.1 - 3 8.3 4.7 1.1 9.7 0.1 2.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) AKNA PF12443.3 EKE42239.1 - 3.1 7.8 11.1 0.58 10.1 4.5 2.0 1 1 0 2 2 2 0 AT-hook-containing transcription factor ALMT PF11744.3 EKE42239.1 - 3.9 6.0 5.0 4.3 5.8 3.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GvpL_GvpF PF06386.6 EKE42239.1 - 4.9 6.6 7.3 6.2 6.3 5.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF WD40 PF00400.27 EKE42240.1 - 5.7e-06 26.0 0.0 0.017 14.9 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_L39 PF00832.15 EKE42242.1 - 2.6e-19 68.4 5.1 2.9e-19 68.2 3.5 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Chitin_synth_2 PF03142.10 EKE42243.1 - 1.4e-23 83.1 0.0 1.4e-23 83.1 0.0 4.1 4 1 0 5 5 5 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EKE42243.1 - 1.7e-19 70.2 0.1 1.7e-19 70.2 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKE42243.1 - 6.1e-13 49.1 0.0 9.6e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EKE42243.1 - 0.00013 21.7 0.1 0.0011 18.7 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 2 Sen15 PF09631.5 EKE42243.1 - 0.063 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Sen15 protein TPR_11 PF13414.1 EKE42244.1 - 2.5e-10 39.8 1.7 3.3e-06 26.6 0.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKE42244.1 - 3.4e-10 39.0 0.4 5.5e-05 22.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.23 EKE42244.1 - 5.7e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.12 EKE42244.1 - 5.3e-07 29.0 0.5 0.0009 18.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKE42244.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKE42244.1 - 0.036 13.8 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKE42244.1 - 0.045 14.3 0.1 0.093 13.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SecA_PP_bind PF01043.15 EKE42244.1 - 0.19 12.1 0.9 0.66 10.3 0.2 2.0 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Pkinase PF00069.20 EKE42245.1 - 1.1e-35 123.0 0.4 3.6e-35 121.3 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42245.1 - 5.4e-17 61.7 1.4 6.8e-16 58.1 0.2 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42245.1 - 0.0019 17.2 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EKE42245.1 - 0.0024 16.7 0.7 0.0043 15.9 0.5 1.5 1 1 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EKE42245.1 - 0.0064 15.8 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EKE42245.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Baculo_PP31 PF05311.6 EKE42245.1 - 0.21 10.8 3.2 0.32 10.2 2.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Muted PF14942.1 EKE42246.1 - 0.01 15.7 0.7 0.01 15.7 0.5 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF919 PF06034.6 EKE42246.1 - 0.041 13.5 3.3 0.12 12.0 2.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) NTF2 PF02136.15 EKE42247.1 - 4.4e-19 69.0 0.2 5e-19 68.8 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SNF2_N PF00176.18 EKE42248.1 - 3.7e-67 226.2 0.6 3.7e-67 226.2 0.4 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKE42248.1 - 8e-18 64.0 0.0 2.4e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLIDE PF09111.5 EKE42248.1 - 1.7e-07 30.9 1.0 1.7e-07 30.9 0.7 2.5 2 0 0 2 2 2 1 SLIDE Helicase_C_4 PF13871.1 EKE42248.1 - 0.0014 18.1 0.1 0.0031 17.0 0.1 1.5 1 0 0 1 1 1 1 Helicase_C-like Myb_DNA-bind_6 PF13921.1 EKE42248.1 - 0.034 14.2 1.8 5.9 7.0 0.0 3.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain EF-hand_7 PF13499.1 EKE42249.1 - 4.1e-26 90.8 28.7 2.9e-11 43.3 0.3 7.9 4 1 4 8 8 8 6 EF-hand domain pair EF-hand_1 PF00036.27 EKE42249.1 - 5.3e-16 56.6 22.7 0.0043 16.2 0.0 9.8 10 0 0 10 10 10 5 EF hand EF-hand_8 PF13833.1 EKE42249.1 - 7.3e-12 44.7 13.0 0.00026 20.5 0.1 6.4 4 2 1 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 EKE42249.1 - 4.3e-11 41.7 26.5 0.74 9.8 0.0 10.6 10 1 0 10 10 10 4 EF-hand domain EF-hand_5 PF13202.1 EKE42249.1 - 4.8e-09 35.1 4.6 0.049 12.9 0.0 6.2 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 EKE42249.1 - 6.2e-05 22.9 11.1 0.32 11.0 0.4 5.4 3 2 3 6 6 6 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKE42249.1 - 8.9e-05 22.1 13.3 0.041 13.6 0.0 6.3 4 3 3 7 7 7 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EKE42249.1 - 0.011 15.6 1.7 3.6 7.5 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain DUF482 PF04339.7 EKE42249.1 - 0.033 13.0 0.3 0.3 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF482 DUF3737 PF12541.3 EKE42250.1 - 0.0049 15.8 0.5 0.006 15.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3737) YrpD PF15493.1 EKE42250.1 - 0.025 14.2 0.2 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, YrpD DUF3391 PF11871.3 EKE42250.1 - 0.098 12.8 0.6 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) RRM_6 PF14259.1 EKE42251.1 - 0.0017 18.2 0.1 0.004 17.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE42251.1 - 0.0089 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.13 EKE42252.1 - 2.6e-14 52.4 1.1 4.7e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 NAC domain Transposase_24 PF03004.9 EKE42252.1 - 0.0084 16.0 2.7 0.012 15.4 1.9 1.4 1 1 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) RRP7 PF12923.2 EKE42252.1 - 0.014 15.3 4.6 0.021 14.8 3.2 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) UBA PF00627.26 EKE42252.1 - 0.055 13.3 0.1 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain DUF4193 PF13834.1 EKE42252.1 - 0.07 13.3 3.7 0.11 12.6 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4193) DAP PF15228.1 EKE42252.1 - 0.087 13.5 2.4 0.18 12.5 1.7 1.5 1 0 0 1 1 1 0 Death-associated protein PAP2 PF01569.16 EKE42255.1 - 1.3e-20 73.3 1.8 1.3e-20 73.3 1.2 1.7 1 1 1 2 2 2 1 PAP2 superfamily DUF4131 PF13567.1 EKE42255.1 - 0.0039 16.6 1.7 0.48 9.8 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) Scs3p PF10261.4 EKE42255.1 - 0.039 12.9 0.1 0.063 12.3 0.1 1.4 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Pox_A14 PF05767.7 EKE42255.1 - 0.48 10.4 7.1 7.3 6.6 0.1 2.9 2 2 0 2 2 2 0 Poxvirus virion envelope protein A14 DAO PF01266.19 EKE42255.1 - 2.1 7.1 3.3 3.2 6.5 2.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4583 PF15190.1 EKE42255.1 - 4.7 6.8 8.6 1.3 8.7 2.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4583) DUF4158 PF13700.1 EKE42256.1 - 0.0046 16.4 2.0 0.42 10.0 0.1 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF4158) RabGAP-TBC PF00566.13 EKE42258.1 - 3e-37 128.1 8.0 3e-37 128.1 5.6 3.3 3 1 0 4 4 4 1 Rab-GTPase-TBC domain Transketolase_N PF00456.16 EKE42258.1 - 1.5 7.5 13.5 0.28 9.9 0.4 2.3 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain DZF PF07528.9 EKE42258.1 - 2.5 7.4 5.7 4.7 6.5 3.9 1.4 1 0 0 1 1 1 0 DZF domain SprA-related PF12118.3 EKE42258.1 - 9.3 5.4 26.8 22 4.2 18.6 1.6 1 0 0 1 1 1 0 SprA-related family Pentapeptide_4 PF13599.1 EKE42259.1 - 1.4 8.7 6.3 1.8 8.4 0.1 3.2 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Ras PF00071.17 EKE42261.1 - 1.7e-40 138.0 1.7 1.9e-40 137.8 1.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42261.1 - 3.8e-17 62.8 0.3 6e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42261.1 - 9.7e-11 41.2 0.2 1.3e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE42261.1 - 1.7e-06 27.5 0.2 5.8e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKE42261.1 - 0.00021 20.7 0.9 0.0019 17.6 0.6 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EKE42261.1 - 0.01 15.7 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EKE42261.1 - 0.026 14.4 2.6 0.24 11.2 0.4 2.5 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 EKE42261.1 - 0.073 12.3 0.6 1.2 8.4 0.4 2.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Exo_endo_phos PF03372.18 EKE42262.1 - 6.4e-15 55.7 0.0 8.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PapD-like PF14874.1 EKE42262.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like WD40 PF00400.27 EKE42264.1 - 8.6e-16 57.1 3.8 4.4e-06 26.3 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 EKE42264.1 - 7.5e-06 25.7 0.2 0.0014 18.3 0.1 2.9 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EKE42264.1 - 0.0033 16.9 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 EKE42264.1 - 0.033 13.3 0.4 5.9 5.9 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.20 EKE42266.1 - 1.5e-37 129.1 0.6 2e-37 128.7 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42266.1 - 9.3e-27 93.7 0.1 1.1e-26 93.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42266.1 - 8.5e-05 21.6 0.1 0.00015 20.8 0.1 1.6 1 1 0 1 1 1 1 Kinase-like RasGAP PF00616.14 EKE42267.1 - 4.1e-35 121.2 2.0 5.4e-35 120.8 0.4 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.1 EKE42267.1 - 3.4e-06 26.5 27.9 0.94 9.7 0.1 10.2 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.28 EKE42267.1 - 0.2 11.8 6.5 14 6.1 0.1 5.0 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EKE42267.1 - 1.1 9.7 6.7 15 6.3 0.1 5.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EKE42267.1 - 4.1 7.1 25.6 3.7 7.2 0.5 5.7 3 3 3 6 6 6 0 Leucine Rich repeats (2 copies) PGA2 PF07543.7 EKE42270.1 - 0.038 13.7 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 RhoGEF PF00621.15 EKE42271.1 - 4.5e-38 130.9 1.1 4.5e-38 130.9 0.8 3.5 2 1 0 2 2 2 1 RhoGEF domain Vasculin PF15337.1 EKE42272.1 - 0.03 14.7 0.3 0.08 13.4 0.1 1.7 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Imm46 PF15585.1 EKE42273.1 - 0.017 15.1 1.5 0.041 13.9 0.2 2.2 2 1 0 2 2 2 0 Immunity protein 46 IMD PF08397.6 EKE42273.1 - 0.051 12.8 11.4 0.086 12.1 5.9 2.8 2 1 0 2 2 2 0 IRSp53/MIM homology domain DUF260 PF03195.9 EKE42273.1 - 0.094 13.0 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF260 LMBR1 PF04791.11 EKE42273.1 - 0.28 9.7 3.4 0.15 10.6 0.8 1.6 1 1 0 2 2 2 0 LMBR1-like membrane protein Pkinase PF00069.20 EKE42274.1 - 6.5e-33 113.9 0.5 8.1e-33 113.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42274.1 - 6.9e-18 64.6 1.2 9.3e-18 64.2 0.8 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42274.1 - 0.00021 20.3 0.0 0.00086 18.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EKE42274.1 - 0.01 14.7 3.3 0.01 14.7 2.3 1.9 1 1 1 2 2 2 0 Seadornavirus VP7 RhoGEF PF00621.15 EKE42275.1 - 1.6e-46 158.4 7.4 1.6e-46 158.4 5.2 3.1 3 1 0 3 3 3 1 RhoGEF domain Chorein_N PF12624.2 EKE42276.1 - 1.9e-07 30.6 0.2 1.9e-07 30.6 0.2 3.0 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter RhoGAP PF00620.22 EKE42280.1 - 1.5e-26 92.8 0.3 2.5e-26 92.1 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain VSP PF03302.8 EKE42281.1 - 8.4e-06 24.6 36.0 8.4e-06 24.6 25.0 5.4 1 1 5 6 6 6 5 Giardia variant-specific surface protein Fe-ADH PF00465.14 EKE42282.1 - 4.4e-64 216.4 0.0 4.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKE42282.1 - 8.8e-05 21.9 0.1 0.00013 21.3 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase IKI3 PF04762.7 EKE42284.1 - 1.9e-58 198.1 6.3 9.2e-58 195.8 3.0 2.5 1 1 0 2 2 2 2 IKI3 family RabGAP-TBC PF00566.13 EKE42285.1 - 1.3e-41 142.4 8.1 2e-41 141.8 5.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPR_1 PF00515.23 EKE42286.1 - 8.9e-38 126.3 24.7 2.7e-07 29.9 0.1 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EKE42286.1 - 1.5e-36 121.3 22.8 3.6e-05 23.3 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 EKE42286.1 - 3.4e-35 119.5 39.8 5.5e-13 48.3 0.1 5.5 3 2 4 7 7 6 6 TPR repeat TPR_8 PF13181.1 EKE42286.1 - 6e-26 88.2 15.7 6.3e-05 22.4 0.1 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EKE42286.1 - 4.7e-23 79.4 20.9 0.0038 17.3 0.1 9.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 EKE42286.1 - 2.2e-22 77.4 0.7 0.00096 19.5 0.1 6.7 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 EKE42286.1 - 2.4e-22 78.6 17.9 2.9e-07 30.3 0.0 5.7 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EKE42286.1 - 7e-20 71.1 4.9 1.4e-07 31.7 0.0 5.6 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKE42286.1 - 6.1e-18 64.9 7.2 0.0011 19.6 0.8 5.2 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EKE42286.1 - 2.6e-12 45.5 5.2 0.00057 19.4 0.3 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKE42286.1 - 8.4e-12 44.7 9.3 0.0023 18.2 0.2 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EKE42286.1 - 5.5e-09 36.0 20.5 9.7e-05 22.4 3.6 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EKE42286.1 - 8e-07 28.8 0.6 0.22 11.4 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EKE42286.1 - 3.3e-06 26.3 2.6 0.013 14.5 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 EKE42286.1 - 0.00012 21.8 2.0 0.73 9.7 0.0 3.9 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EKE42286.1 - 0.0053 16.8 0.7 13 5.9 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EKE42286.1 - 0.051 12.3 2.0 0.78 8.4 0.0 3.0 2 2 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 EKE42286.1 - 0.12 12.3 4.0 3.7 7.6 0.2 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DEAD PF00270.24 EKE42287.1 - 1.5e-39 135.2 1.1 2.7e-39 134.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE42287.1 - 1.9e-22 78.9 0.0 6.6e-22 77.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EKE42287.1 - 9.6e-19 66.6 0.1 2.2e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EKE42287.1 - 0.00085 19.1 2.7 0.019 14.7 0.1 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TSLP PF15216.1 EKE42287.1 - 0.005 16.5 0.4 0.011 15.4 0.3 1.6 1 0 0 1 1 1 1 Thymic stromal lymphopoietin Helicase_C_2 PF13307.1 EKE42287.1 - 0.0067 16.3 0.2 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain Metallophos PF00149.23 EKE42288.1 - 4.2e-34 117.7 0.5 6.7e-34 117.0 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S4 PF01479.20 EKE42288.1 - 0.14 11.5 0.6 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 S4 domain SNARE PF05739.14 EKE42289.1 - 4e-14 52.0 2.2 3.4e-13 49.0 0.4 2.5 2 0 0 2 2 2 1 SNARE domain MCPsignal PF00015.16 EKE42289.1 - 0.00053 19.5 3.0 0.00053 19.5 2.1 2.0 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4064 PF13273.1 EKE42289.1 - 0.0075 16.3 6.8 0.0075 16.3 4.7 2.1 1 1 2 3 3 3 1 Protein of unknown function (DUF4064) Syntaxin PF00804.20 EKE42289.1 - 0.0095 16.0 5.5 0.0095 16.0 3.8 3.1 2 1 0 2 2 2 1 Syntaxin T2SF PF00482.18 EKE42289.1 - 0.074 12.9 2.5 0.11 12.4 0.9 2.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Herpes_US9 PF06072.6 EKE42289.1 - 0.13 12.1 2.2 0.3 10.9 1.5 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Shisa PF13908.1 EKE42289.1 - 0.23 11.6 1.7 0.46 10.6 1.2 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Syntaxin_2 PF14523.1 EKE42289.1 - 0.33 10.9 19.3 0.11 12.5 4.3 2.8 2 1 0 2 2 2 0 Syntaxin-like protein LRRC37AB_C PF14914.1 EKE42289.1 - 3.3 7.1 13.0 0.068 12.6 3.6 2.1 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Salp15 PF12115.3 EKE42289.1 - 4.6 7.4 6.4 2.9 8.1 0.5 2.6 1 1 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation CCDC84 PF14968.1 EKE42289.1 - 6.3 6.2 8.0 9.8 5.5 5.6 1.4 1 1 0 1 1 1 0 Coiled coil protein 84 DUF230 PF03003.11 EKE42289.1 - 9.9 5.7 9.6 0.34 10.4 1.1 2.4 2 1 1 3 3 3 0 Poxvirus proteins of unknown function Ribosomal_S30 PF04758.9 EKE42290.1 - 7.8e-19 67.1 4.5 8.8e-19 67.0 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 PCI PF01399.22 EKE42291.1 - 1.4e-16 60.7 1.1 1.4e-16 60.7 0.7 2.5 3 1 0 3 3 3 1 PCI domain TPR_16 PF13432.1 EKE42291.1 - 0.018 15.6 0.2 0.037 14.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Vps39_1 PF10366.4 EKE42291.1 - 0.038 14.0 0.4 0.038 14.0 0.3 3.0 3 2 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 LRR_5 PF13306.1 EKE42293.1 - 2.5e-77 256.7 48.6 1.8e-29 102.0 5.1 3.8 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42293.1 - 3.8e-33 113.0 26.7 2.3e-07 30.4 0.3 6.8 2 2 6 8 8 8 8 Leucine rich repeat Pentapeptide_3 PF13576.1 EKE42293.1 - 0.02 14.7 2.2 8.9 6.2 0.1 4.6 4 1 0 4 4 4 0 Pentapeptide repeats (9 copies) RasGEF PF00617.14 EKE42294.1 - 3.3e-20 72.5 4.1 5e-20 72.0 1.7 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKE42294.1 - 1.6e-10 40.9 1.0 7.1e-10 38.9 0.1 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif RCC1 PF00415.13 EKE42294.1 - 7e-08 32.5 0.1 2.1e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKE42294.1 - 9.2e-06 25.1 0.1 0.00022 20.7 0.0 2.8 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat PP1_inhibitor PF05361.7 EKE42295.1 - 0.05 13.2 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Hemerythrin PF01814.18 EKE42296.1 - 1.8 8.7 8.7 6 7.0 1.1 3.3 2 2 1 3 3 3 0 Hemerythrin HHE cation binding domain Chromo PF00385.19 EKE42297.1 - 7e-16 57.6 0.7 1.7e-15 56.4 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4389 PF14333.1 EKE42298.1 - 0.31 10.7 11.7 1.5 8.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4389) Sdh_cyt PF01127.17 EKE42298.1 - 3.8 7.3 12.4 2.1 8.2 4.5 2.2 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_C1 PF00112.18 EKE42299.1 - 2.8e-26 92.7 10.0 4.7e-26 92.0 6.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE42299.1 - 0.019 15.2 1.0 0.019 15.2 0.7 2.3 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) PP2C PF00481.16 EKE42300.1 - 3.8e-51 173.9 0.0 6.6e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE42300.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein phosphatase 2C Kinesin PF00225.18 EKE42301.1 - 2.6e-25 88.8 5.6 2.6e-25 88.8 3.9 4.6 3 3 1 4 4 4 1 Kinesin motor domain DUF1413 PF07205.6 EKE42302.1 - 0.0033 16.9 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1413) TLD PF07534.11 EKE42302.1 - 0.057 13.4 1.9 0.081 12.9 0.2 1.9 1 1 0 2 2 2 0 TLD DUF1298 PF06974.8 EKE42304.1 - 8.4e-09 35.3 0.0 1.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.11 EKE42304.1 - 6.3e-06 25.9 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain XG_FTase PF03254.8 EKE42304.1 - 0.013 14.0 0.1 0.023 13.1 0.1 1.4 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase LRR_4 PF12799.2 EKE42306.1 - 5.6e-13 48.1 24.8 7.2e-08 31.8 1.2 5.5 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE42306.1 - 8.9e-06 25.3 17.9 0.00082 19.0 0.5 3.9 4 1 1 5 5 5 3 Leucine rich repeat TroA PF01297.12 EKE42306.1 - 0.011 15.0 0.5 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Periplasmic solute binding protein family PDZ_2 PF13180.1 EKE42306.1 - 0.034 14.0 0.4 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 PDZ domain LRR_7 PF13504.1 EKE42306.1 - 0.053 13.7 18.3 0.28 11.5 0.0 5.9 7 0 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 EKE42306.1 - 0.067 13.2 26.4 0.41 10.8 0.1 7.4 7 1 0 7 7 7 0 Leucine Rich Repeat UQ_con PF00179.21 EKE42307.1 - 1.5e-48 163.7 0.1 1.7e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CpXC PF14353.1 EKE42307.1 - 0.0094 15.9 0.4 0.017 15.0 0.3 1.5 1 1 0 1 1 1 1 CpXC protein Lar_restr_allev PF14354.1 EKE42307.1 - 0.043 14.1 0.4 0.068 13.4 0.3 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Prok-E2_B PF14461.1 EKE42307.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B DUF2048 PF09752.4 EKE42307.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Pkinase PF00069.20 EKE42309.1 - 6.3e-51 173.0 0.0 1.4e-50 171.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42309.1 - 3.2e-50 170.6 0.0 5.6e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKE42309.1 - 0.5 9.3 0.0 0.88 8.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.17 EKE42310.1 - 1e-20 71.8 5.4 0.009 16.0 0.0 8.0 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 EKE42310.1 - 1.4e-16 60.5 0.0 0.0001 22.5 0.0 4.2 1 1 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EKE42310.1 - 1.4e-06 28.6 6.1 0.13 12.8 0.0 5.1 4 3 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 EKE42310.1 - 1.2e-05 25.1 3.7 0.69 9.7 0.0 4.0 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EKE42310.1 - 1.6e-05 23.4 3.5 0.0019 16.5 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region DUF3385 PF11865.3 EKE42310.1 - 0.12 12.2 0.5 13 5.7 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) DUF4042 PF13251.1 EKE42310.1 - 0.36 10.2 3.4 7.1 6.0 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) Ras PF00071.17 EKE42311.1 - 2.2e-54 183.2 0.8 2.5e-54 183.0 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42311.1 - 4.2e-19 69.2 0.0 7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42311.1 - 2.9e-12 46.1 0.2 3.6e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE42311.1 - 4.9e-06 26.1 0.6 1.8e-05 24.2 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE42311.1 - 2.2e-05 24.3 0.1 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKE42311.1 - 0.00014 21.1 0.2 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EKE42311.1 - 0.0039 16.4 1.4 0.061 12.5 1.0 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EKE42311.1 - 0.0065 16.0 0.6 0.015 14.8 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EKE42311.1 - 0.053 12.6 0.3 0.078 12.1 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 EKE42311.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DAP3 PF10236.4 EKE42311.1 - 0.073 11.9 0.4 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Trp_syntA PF00290.15 EKE42312.1 - 0.056 11.9 0.2 2.4 6.6 0.0 2.6 2 1 1 3 3 3 0 Tryptophan synthase alpha chain NYD-SP28 PF14772.1 EKE42312.1 - 0.32 11.1 2.2 0.52 10.4 0.7 1.8 2 0 0 2 2 2 0 Sperm tail ODR4-like PF14778.1 EKE42313.1 - 0.00046 19.0 0.1 0.00047 18.9 0.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like Sec62 PF03839.11 EKE42314.1 - 0.0024 17.3 1.0 0.0032 16.9 0.7 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 PalH PF08733.5 EKE42314.1 - 0.0083 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 PalH/RIM21 DUF912 PF06024.7 EKE42314.1 - 0.056 13.4 3.9 0.073 13.1 2.3 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mem_trans PF03547.13 EKE42314.1 - 0.069 11.4 2.2 0.077 11.2 1.5 1.1 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.12 EKE42314.1 - 0.45 10.2 3.8 0.57 9.9 2.7 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_A21 PF03566.8 EKE42314.1 - 2.4 6.1 5.0 2.4 6.1 3.4 1.0 1 0 0 1 1 1 0 Peptidase family A21 DUF4481 PF14800.1 EKE42314.1 - 4.9 5.9 7.3 0.42 9.4 1.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4481) TLD PF07534.11 EKE42317.1 - 1e-07 32.0 0.6 2.5e-07 30.7 0.4 1.7 1 0 0 1 1 1 1 TLD CH PF00307.26 EKE42317.1 - 1.8e-05 24.7 0.2 0.13 12.3 0.0 3.0 2 0 0 2 2 2 2 Calponin homology (CH) domain S1 PF00575.18 EKE42318.1 - 3.1e-23 81.6 56.6 1.5e-08 34.6 1.0 11.8 10 1 2 12 12 12 9 S1 RNA binding domain S1_2 PF13509.1 EKE42318.1 - 1.4 8.8 15.5 8.6 6.3 0.0 7.4 8 0 0 8 8 8 0 S1 domain Nucleoside_tran PF01733.13 EKE42319.1 - 4.1e-15 55.7 23.1 4.1e-15 55.7 16.0 2.9 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EKE42319.1 - 2.1e-07 29.9 46.3 8.1e-07 28.0 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DcpS_C PF11969.3 EKE42320.1 - 2.3e-22 79.4 2.1 4.6e-22 78.4 1.4 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EKE42320.1 - 2.5e-05 24.6 1.3 7.2e-05 23.1 0.9 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal SapB_1 PF05184.10 EKE42321.1 - 0.00023 20.9 0.4 0.00023 20.9 0.3 2.5 3 0 0 3 3 3 1 Saposin-like type B, region 1 Guanylin PF02058.10 EKE42321.1 - 0.06 13.4 0.9 0.12 12.4 0.2 1.8 2 0 0 2 2 2 0 Guanylin precursor Pkinase PF00069.20 EKE42322.1 - 6.3e-42 143.5 0.0 1.5e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42322.1 - 1.9e-40 138.6 0.0 3.5e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE42322.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNARE_assoc PF09335.6 EKE42323.1 - 2.5e-09 37.3 3.7 2.5e-09 37.3 2.6 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein SHP PF03579.8 EKE42323.1 - 0.0058 15.9 0.6 0.0058 15.9 0.4 2.7 4 0 0 4 4 4 1 Small hydrophobic protein Ion_trans_2 PF07885.11 EKE42323.1 - 5.9 6.6 15.2 0.46 10.2 5.8 2.6 2 1 0 2 2 2 0 Ion channel DEAD PF00270.24 EKE42324.1 - 4.7e-47 159.6 1.0 1.1e-46 158.4 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE42324.1 - 1.2e-23 82.7 0.0 4.2e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EKE42324.1 - 9.5e-19 66.7 0.0 2e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EKE42324.1 - 1e-05 25.4 0.6 1e-05 25.4 0.4 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EKE42324.1 - 0.03 13.6 4.1 0.095 11.9 2.8 1.8 1 1 0 1 1 1 0 SecA DEAD-like domain Tim54 PF11711.3 EKE42324.1 - 0.088 11.3 3.8 0.13 10.8 2.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ldh_2 PF02615.9 EKE42325.1 - 6.8e-88 294.6 0.0 8.2e-88 294.3 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF367 PF04034.8 EKE42325.1 - 0.019 14.5 0.1 0.66 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF367) Pkinase_Tyr PF07714.12 EKE42326.1 - 2e-54 184.4 0.0 3.3e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE42326.1 - 1.1e-50 172.1 0.0 2e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PPC PF04151.10 EKE42326.1 - 7.7 7.5 8.2 0.21 12.6 0.5 2.4 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain YabP PF07873.6 EKE42327.1 - 0.076 12.5 0.4 0.18 11.3 0.1 1.8 2 0 0 2 2 2 0 YabP family Glyco_hydro_42C PF08533.5 EKE42328.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain DUF262 PF03235.9 EKE42328.1 - 0.94 9.4 9.4 1.4 8.8 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 PA26 PF04636.8 EKE42328.1 - 1.4 7.5 9.3 2.4 6.7 6.5 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cwf_Cwc_15 PF04889.7 EKE42328.1 - 5.6 6.6 17.1 7.2 6.2 11.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUSP PF06337.7 EKE42328.1 - 6.3 7.2 7.7 14 6.1 5.3 1.6 1 0 0 1 1 1 0 DUSP domain Proteasome PF00227.21 EKE42329.1 - 1e-51 174.9 0.2 1.2e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKE42329.1 - 2.1e-12 46.1 0.0 4.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NPV_P10 PF05531.7 EKE42329.1 - 0.035 14.3 2.7 1.7 8.9 1.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.3 EKE42329.1 - 0.069 13.2 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus ComC PF03047.9 EKE42329.1 - 0.19 11.1 4.6 2.5 7.6 1.3 2.3 2 0 0 2 2 2 0 COMC family PAP2_C PF14360.1 EKE42330.1 - 2.3e-10 40.5 10.3 2.3e-10 40.5 7.1 3.6 3 2 1 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EKE42330.1 - 1.7e-05 24.4 6.2 1.7e-05 24.4 4.3 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EKE42330.1 - 0.0009 18.8 10.5 0.11 12.0 1.5 2.7 2 1 0 2 2 2 2 PAP2 superfamily NPR3 PF03666.8 EKE42331.1 - 6.6e-33 113.9 7.2 1.5e-16 59.9 0.9 2.1 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Spy1 PF11357.3 EKE42331.1 - 0.0022 18.0 0.4 3.2 7.8 0.0 2.5 2 0 0 2 2 2 2 Cell cycle regulatory protein HMG_box PF00505.14 EKE42332.1 - 7.3e-12 45.3 4.4 7.3e-12 45.3 3.1 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE42332.1 - 7.6e-07 29.4 6.3 7.6e-07 29.4 4.4 2.5 2 1 0 2 2 2 1 HMG-box domain A_thal_3526 PF09713.5 EKE42332.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) FAM176 PF14851.1 EKE42332.1 - 0.11 12.2 4.9 0.029 14.0 1.2 1.6 1 1 1 2 2 2 0 FAM176 family CbiC PF02570.10 EKE42332.1 - 0.28 10.5 2.6 0.35 10.2 1.8 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase Ribosomal_L28 PF00830.14 EKE42333.1 - 0.016 14.9 1.4 0.029 14.2 1.0 1.4 1 0 0 1 1 1 0 Ribosomal L28 family FAM60A PF15396.1 EKE42333.1 - 8.9 5.9 9.5 12 5.6 6.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A tRNA-synt_1 PF00133.17 EKE42334.1 - 4.1e-223 741.7 0.1 5.8e-223 741.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EKE42334.1 - 6.1e-31 107.2 0.2 1.9e-30 105.6 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EKE42334.1 - 4.3e-18 65.1 0.2 9.9e-06 24.4 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EKE42334.1 - 0.0031 16.6 0.0 0.0087 15.2 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.17 EKE42335.1 - 3.3e-08 33.0 0.0 5.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE42335.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.20 EKE42339.1 - 4.4e-22 77.7 1.4 6.6e-22 77.2 0.1 2.0 2 0 0 2 2 2 1 Bromodomain Myotub-related PF06602.9 EKE42340.1 - 2.4e-103 345.6 0.6 3.7e-103 345.0 0.4 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EKE42340.1 - 0.0045 17.2 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EKE42340.1 - 0.0056 16.0 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Xpo1 PF08389.7 EKE42340.1 - 0.0056 16.5 1.7 0.0079 16.1 0.2 1.9 2 0 0 2 2 2 1 Exportin 1-like protein DSPc PF00782.15 EKE42340.1 - 0.013 15.1 0.1 0.041 13.4 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain SMC_N PF02463.14 EKE42341.1 - 7.6e-25 87.4 39.6 3.4e-24 85.2 26.2 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKE42341.1 - 3e-24 85.2 0.0 8.8e-24 83.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EKE42341.1 - 3.3e-14 53.7 20.2 3.3e-14 53.7 14.0 6.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EKE42341.1 - 7.3e-06 26.1 0.1 7.3e-06 26.1 0.1 4.8 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 EKE42341.1 - 2.2e-05 23.8 0.1 6.2e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EKE42341.1 - 0.31 11.3 0.1 0.31 11.3 0.0 5.3 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 EKE42342.1 - 0.00014 20.5 22.6 0.00014 20.5 15.7 6.1 1 1 4 6 6 6 1 AAA domain XhlA PF10779.4 EKE42342.1 - 0.013 15.4 4.0 0.013 15.4 2.8 11.6 4 3 5 10 10 10 0 Haemolysin XhlA PulS_OutS PF09691.5 EKE42342.1 - 0.014 15.3 0.9 0.014 15.3 0.6 5.7 4 1 2 6 6 6 0 Bacterial chaperone lipoprotein (PulS_OutS) Conotoxin PF02950.12 EKE42343.1 - 0.017 15.9 0.1 0.019 15.7 0.0 1.1 1 0 0 1 1 1 0 Conotoxin FAM176 PF14851.1 EKE42343.1 - 0.14 11.8 2.1 0.16 11.6 1.5 1.1 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 EKE42343.1 - 0.42 9.5 8.1 0.44 9.5 5.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 EKE42343.1 - 1.8 6.2 5.3 1.7 6.4 3.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 EKE42343.1 - 6.4 6.5 9.3 6.8 6.4 6.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 EKE42343.1 - 8.4 5.0 14.5 8.1 5.0 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CPSF_A PF03178.10 EKE42344.1 - 2.5e-57 194.4 1.1 8.7e-53 179.4 0.0 3.1 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 EKE42344.1 - 2.7e-44 151.1 3.5 2.7e-44 151.1 2.4 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term IF2_N PF04760.10 EKE42344.1 - 0.055 13.1 0.7 0.12 12.0 0.5 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region TLD PF07534.11 EKE42345.1 - 0.0028 17.6 4.2 0.0028 17.6 2.9 1.8 2 0 0 2 2 2 1 TLD TLD PF07534.11 EKE42346.1 - 0.0091 15.9 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 TLD Pepsin-I3 PF06394.8 EKE42346.1 - 0.061 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain RPN7 PF10602.4 EKE42347.1 - 0.076 12.3 0.1 0.076 12.3 0.1 1.1 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Peptidase_C1 PF00112.18 EKE42349.1 - 0.0027 17.6 13.0 0.013 15.4 0.2 2.9 1 1 1 2 2 2 1 Papain family cysteine protease RecO_N_2 PF13114.1 EKE42349.1 - 0.02 14.5 0.1 0.069 12.8 0.1 1.9 1 0 0 1 1 1 0 RecO N terminal DUF1825 PF08855.5 EKE42349.1 - 0.036 14.0 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) RasGAP PF00616.14 EKE42350.1 - 3.6e-16 59.4 4.6 3.6e-16 59.4 3.2 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RRM_5 PF13893.1 EKE42351.1 - 0.0016 18.2 0.1 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toprim PF01751.17 EKE42351.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Toprim domain RRM_6 PF14259.1 EKE42351.1 - 0.045 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MRP-S23 PF10484.4 EKE42352.1 - 0.078 12.8 0.1 0.32 10.8 0.0 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 4HB_MCP_1 PF12729.2 EKE42352.1 - 0.22 10.8 2.2 0.1 11.9 0.3 1.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Arm PF00514.18 EKE42353.1 - 2.6e-07 30.1 4.4 8.4e-05 22.2 0.1 3.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EKE42353.1 - 0.017 15.1 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat Guanylin PF02058.10 EKE42353.1 - 0.061 13.4 0.3 0.18 11.8 0.2 1.9 1 0 0 1 1 1 0 Guanylin precursor SPRY PF00622.23 EKE42354.1 - 1.7e-09 37.7 0.2 5.3e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 SPRY domain DUF3373 PF11853.3 EKE42354.1 - 0.061 11.8 6.0 0.11 10.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PBD PF00786.23 EKE42354.1 - 1.1 9.7 6.6 0.99 9.8 0.5 3.1 3 0 0 3 3 3 0 P21-Rho-binding domain DUF2492 PF10678.4 EKE42355.1 - 0.16 12.0 5.2 0.069 13.2 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) Gcd10p PF04189.8 EKE42356.1 - 1.1e-45 156.0 2.9 2.8e-45 154.7 2.0 1.6 1 1 0 1 1 1 1 Gcd10p family Rep_fac_C PF08542.6 EKE42356.1 - 0.057 13.4 0.0 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 Replication factor C C-terminal domain Glyco_transf_5 PF08323.6 EKE42357.1 - 3.2e-32 111.9 0.0 6.4e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EKE42357.1 - 1.3e-14 54.0 0.0 3.4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EKE42357.1 - 0.022 14.8 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 RasGEF PF00617.14 EKE42360.1 - 2.8e-14 53.2 1.5 1.2e-13 51.2 1.1 2.1 1 1 0 1 1 1 1 RasGEF domain YfzA PF14118.1 EKE42360.1 - 0.11 12.6 3.5 0.26 11.4 0.5 3.0 2 1 1 3 3 3 0 YfzA-like protein IncA PF04156.9 EKE42362.1 - 0.0084 15.7 13.5 0.0084 15.7 9.3 6.0 1 1 3 4 4 4 1 IncA protein DUF2673 PF10880.3 EKE42362.1 - 0.081 12.9 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) Peptidase_C1 PF00112.18 EKE42363.1 - 1.3e-08 35.0 0.2 0.00069 19.5 0.1 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EKE42363.1 - 0.046 12.2 0.2 4.8 5.5 0.2 2.2 2 0 0 2 2 2 0 Peptidase C1-like family Ribophorin_I PF04597.9 EKE42364.1 - 8.5e-46 156.3 9.3 1.1e-45 155.9 6.5 1.0 1 0 0 1 1 1 1 Ribophorin I TPR_1 PF00515.23 EKE42365.1 - 0.42 10.2 2.5 0.71 9.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKE42365.1 - 1.8 8.5 6.2 5.6 6.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SIS PF01380.17 EKE42366.1 - 1.6e-35 121.5 2.3 1.2e-18 67.0 0.2 3.3 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.1 EKE42366.1 - 1.6e-20 73.4 0.0 2.9e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EKE42366.1 - 1.1e-16 60.4 0.9 2.2e-12 46.3 0.1 3.0 2 1 0 3 3 3 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EKE42366.1 - 1.1e-15 57.5 0.0 2.3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EKE42366.1 - 3.2e-07 29.3 0.1 6e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II WBS_methylT PF12589.3 EKE42367.1 - 1.9e-19 69.9 7.9 3.4e-19 69.1 5.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EKE42367.1 - 2.5e-13 50.3 0.0 4.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE42367.1 - 5.6e-13 48.7 0.0 7.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKE42367.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE42367.1 - 2.2e-07 30.7 0.0 4.3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE42367.1 - 1.7e-06 28.0 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE42367.1 - 2.8e-06 27.8 0.0 5.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE42367.1 - 5.2e-05 23.6 0.0 0.00011 22.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EKE42367.1 - 0.00018 20.9 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EKE42367.1 - 0.0037 16.6 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EKE42367.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EKE42367.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_3_Rpc31 PF11705.3 EKE42368.1 - 1.5 8.6 13.6 4.3 7.2 9.1 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 HIM1 PF08732.5 EKE42369.1 - 0.011 14.1 0.3 0.018 13.4 0.2 1.7 1 1 0 1 1 1 0 HIM1 RAB3GAP2_N PF14655.1 EKE42370.1 - 1.7e-05 24.0 0.2 0.0026 16.8 0.0 2.7 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Utp8 PF10395.4 EKE42370.1 - 0.0084 14.4 0.3 0.0084 14.4 0.2 1.5 2 0 0 2 2 2 1 Utp8 family CPSF_A PF03178.10 EKE42371.1 - 4.2e-56 190.3 11.0 2.1e-55 188.0 1.9 3.6 4 0 0 4 4 4 2 CPSF A subunit region MMS1_N PF10433.4 EKE42371.1 - 4.6e-27 94.3 2.3 4.6e-27 94.3 1.6 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Vps39_2 PF10367.4 EKE42372.1 - 0.00046 20.3 3.5 0.00091 19.3 0.5 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 EKE42372.1 - 0.0071 16.0 8.3 0.0071 16.0 5.8 2.3 3 0 0 3 3 3 1 zinc-RING finger domain Amido_AtzD_TrzD PF09663.5 EKE42372.1 - 0.16 10.5 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) IF4E PF01652.13 EKE42375.1 - 7.2e-24 84.1 0.2 9e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TLD PF07534.11 EKE42376.1 - 3e-10 40.2 3.6 3.5e-10 40.0 2.3 1.3 1 1 0 1 1 1 1 TLD RasGEF PF00617.14 EKE42378.1 - 1.5e-08 34.5 5.5 1.5e-06 28.1 3.8 2.4 1 1 0 1 1 1 1 RasGEF domain Toxin_33 PF08121.6 EKE42378.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Waglerin family SAM_adeno_trans PF01887.11 EKE42379.1 - 7.8e-59 198.8 0.5 9.3e-59 198.5 0.4 1.1 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase Methyltransf_15 PF09445.5 EKE42380.1 - 2.9e-27 95.2 0.1 4.1e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EKE42380.1 - 1.4e-08 34.7 0.0 2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EKE42380.1 - 4.9e-08 32.7 0.0 5.8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EKE42380.1 - 1.2e-06 28.3 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EKE42380.1 - 8.1e-06 25.3 0.0 9.9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EKE42380.1 - 1.4e-05 25.5 0.0 2.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE42380.1 - 1.5e-05 24.6 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE42380.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain TRM PF02005.11 EKE42380.1 - 0.0054 15.7 0.0 0.0069 15.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase TehB PF03848.9 EKE42380.1 - 0.021 14.0 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cupin_2 PF07883.6 EKE42381.1 - 4.3e-09 35.7 0.9 5.4e-09 35.4 0.6 1.1 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 EKE42381.1 - 0.044 13.4 0.4 0.055 13.0 0.3 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DUF872 PF05915.7 EKE42382.1 - 2 8.2 6.2 1.2 8.9 0.1 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) RhoGAP PF00620.22 EKE42383.1 - 3.9e-36 123.9 0.1 8.1e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain NUC173 PF08161.7 EKE42384.1 - 1.4e-14 53.8 15.3 2.7e-13 49.7 0.5 5.1 6 0 0 6 6 6 3 NUC173 domain PAP2_C PF14360.1 EKE42385.1 - 3.3e-22 78.5 6.1 3.3e-22 78.5 4.2 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EKE42385.1 - 0.00055 19.6 8.0 0.00055 19.6 5.5 1.9 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EKE42385.1 - 0.016 14.7 6.2 0.047 13.2 4.3 1.8 1 1 0 1 1 1 0 PAP2 superfamily DUF1212 PF06738.7 EKE42385.1 - 0.071 12.5 1.6 0.18 11.2 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF2628 PF10947.3 EKE42385.1 - 3 7.6 11.3 2.7 7.8 2.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2628) Ras PF00071.17 EKE42386.1 - 2.5e-28 98.4 0.7 3e-28 98.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42386.1 - 3.6e-11 43.5 0.1 7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42386.1 - 9e-08 31.5 0.3 1.2e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE42386.1 - 2.2e-06 27.5 0.2 4.6e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE42386.1 - 3e-06 26.6 0.1 0.00023 20.4 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EKE42386.1 - 0.00023 20.6 0.1 0.12 11.8 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKE42386.1 - 0.00052 19.5 0.1 0.0071 15.8 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EKE42386.1 - 0.004 17.3 0.0 0.076 13.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKE42386.1 - 0.018 14.9 0.6 0.049 13.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EKE42386.1 - 0.021 13.5 0.2 0.16 10.5 0.0 2.2 1 1 2 3 3 3 0 AAA domain CdhD PF03599.11 EKE42386.1 - 0.022 13.2 0.0 0.032 12.7 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Gtr1_RagA PF04670.7 EKE42386.1 - 0.022 13.9 0.2 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.13 EKE42386.1 - 0.028 13.4 0.3 0.051 12.5 0.2 1.7 1 1 0 1 1 1 0 Septin AAA_16 PF13191.1 EKE42386.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Ank PF00023.25 EKE42387.1 - 6e-21 73.1 1.0 3e-09 36.2 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EKE42387.1 - 6.5e-21 73.8 4.1 6.4e-09 35.7 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKE42387.1 - 1.2e-20 73.4 1.3 5.8e-12 45.7 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE42387.1 - 1.9e-19 69.7 0.1 2e-15 56.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKE42387.1 - 9.3e-13 47.0 2.7 7.3e-06 25.7 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeat YlbD_coat PF14071.1 EKE42388.1 - 2.3 8.3 11.1 5.6 7.0 1.0 3.7 3 2 1 4 4 4 0 Putative coat protein Peptidase_M1 PF01433.15 EKE42389.1 - 3.7e-110 368.6 0.0 5.7e-110 368.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EKE42389.1 - 1e-30 107.1 0.0 1.4e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EKE42389.1 - 2.9e-18 66.1 0.0 6.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF955 PF06114.8 EKE42389.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF45 PF01863.12 EKE42389.1 - 0.095 12.4 0.0 3.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF45 HEAT_2 PF13646.1 EKE42389.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats RNA_pol_L_2 PF13656.1 EKE42390.1 - 1.7e-23 81.8 0.0 1.8e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EKE42390.1 - 5.6e-09 35.0 0.0 7.1e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF663 PF04950.7 EKE42391.1 - 9.1e-60 202.1 0.9 1.6e-59 201.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EKE42391.1 - 0.0062 16.0 1.7 0.0078 15.7 0.1 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain BSP_II PF05432.6 EKE42391.1 - 1.6 7.9 25.0 6.8 5.8 17.3 1.8 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pkinase PF00069.20 EKE42393.1 - 2.9e-67 226.5 0.3 3.9e-67 226.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42393.1 - 1.3e-39 135.8 0.1 2e-39 135.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42393.1 - 9.4e-08 31.3 0.1 8.9e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like POLO_box PF00659.13 EKE42393.1 - 2.5e-07 30.5 3.5 7.7e-07 28.9 0.1 2.7 2 0 0 2 2 2 1 POLO box duplicated region RIO1 PF01163.17 EKE42393.1 - 0.0028 17.0 0.2 0.006 15.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family DUF4520 PF15016.1 EKE42393.1 - 0.096 12.2 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Kdo PF06293.9 EKE42393.1 - 0.16 11.0 0.2 0.26 10.3 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-DHHC PF01529.15 EKE42395.1 - 9.2e-26 90.2 26.8 9.2e-26 90.2 18.6 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF605 PF04652.11 EKE42397.1 - 0.00017 21.1 16.6 0.00021 20.8 11.5 1.4 1 0 0 1 1 1 1 Vta1 like IMD PF08397.6 EKE42397.1 - 0.0029 16.9 4.0 0.0062 15.8 2.8 1.5 1 0 0 1 1 1 1 IRSp53/MIM homology domain Fez1 PF06818.10 EKE42397.1 - 0.012 15.5 2.3 0.012 15.5 1.6 1.7 2 0 0 2 2 2 0 Fez1 KaiC PF06745.8 EKE42397.1 - 0.08 12.0 0.6 0.43 9.6 0.0 2.2 1 1 1 2 2 2 0 KaiC TBCA PF02970.11 EKE42397.1 - 0.15 12.1 7.4 9.9 6.3 0.2 3.3 1 1 2 3 3 3 0 Tubulin binding cofactor A FliJ PF02050.11 EKE42397.1 - 0.94 9.5 7.2 0.22 11.6 0.5 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein Pribosyltran_N PF13793.1 EKE42398.1 - 9.9e-17 60.7 0.0 7.4e-15 54.7 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EKE42398.1 - 4.6e-14 52.5 0.6 8.6e-14 51.6 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EKE42398.1 - 1.1e-08 34.8 0.0 8.4e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Creatininase PF02633.9 EKE42398.1 - 0.00086 18.4 0.0 0.11 11.5 0.0 2.7 2 1 0 2 2 2 2 Creatinine amidohydrolase UPRTase PF14681.1 EKE42398.1 - 0.0076 15.4 0.2 0.025 13.8 0.1 1.8 1 1 1 2 2 2 1 Uracil phosphoribosyltransferase V_ATPase_I PF01496.14 EKE42399.1 - 2.2e-66 224.2 0.3 2.7e-66 223.9 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Vac_Fusion PF02346.11 EKE42399.1 - 0.021 14.2 0.2 0.021 14.2 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Uds1 PF15456.1 EKE42399.1 - 0.11 12.4 1.9 0.2 11.6 1.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation ArfGap PF01412.13 EKE42400.1 - 9.2e-34 115.7 0.5 9.2e-34 115.7 0.3 1.7 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Pkinase PF00069.20 EKE42402.1 - 6.1e-72 241.8 0.1 7.3e-72 241.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42402.1 - 1.9e-35 122.1 0.0 2.5e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42402.1 - 2.1e-09 36.8 0.0 2.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EKE42402.1 - 6.8e-06 26.5 1.5 1.4e-05 25.4 1.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 EKE42402.1 - 0.085 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRP3 PF08572.5 EKE42402.1 - 0.12 11.7 0.4 0.24 10.7 0.3 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Pkinase PF00069.20 EKE42403.1 - 2.6e-56 190.6 0.3 4.5e-56 189.8 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42403.1 - 3.4e-23 82.0 0.1 5.5e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EKE42403.1 - 8.9e-05 22.1 1.8 8.9e-05 22.1 1.3 2.9 2 1 1 3 3 3 1 Choline/ethanolamine kinase RIO1 PF01163.17 EKE42403.1 - 0.0022 17.3 0.2 0.0022 17.3 0.2 2.4 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 EKE42403.1 - 0.17 11.6 0.0 0.43 10.2 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EKE42406.1 - 5.6e-31 107.5 0.6 9e-31 106.8 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE42406.1 - 2e-26 92.6 2.2 2.9e-26 92.1 1.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EKE42406.1 - 0.0022 16.9 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HSF_DNA-bind PF00447.12 EKE42407.1 - 3.4e-23 81.7 3.3 3.8e-23 81.6 0.2 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding DUF1664 PF07889.7 EKE42407.1 - 0.0051 16.6 1.1 0.0073 16.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) SlyX PF04102.7 EKE42407.1 - 0.0095 16.2 0.6 0.019 15.3 0.4 1.5 1 0 0 1 1 1 1 SlyX Baculo_PEP_C PF04513.7 EKE42407.1 - 0.049 13.4 0.3 0.067 13.0 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1580 PF07618.6 EKE42407.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) CorA PF01544.13 EKE42407.1 - 0.087 11.8 2.4 0.12 11.4 1.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EKE42407.1 - 0.12 11.9 0.3 0.14 11.7 0.2 1.1 1 0 0 1 1 1 0 IncA protein Syntaxin PF00804.20 EKE42407.1 - 0.2 11.8 3.0 0.77 9.9 2.1 1.8 1 1 0 1 1 1 0 Syntaxin Tubulin PF00091.20 EKE42408.1 - 4.6e-72 242.3 0.0 9.5e-72 241.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKE42408.1 - 3.1e-38 130.6 0.5 6.2e-38 129.6 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EKE42408.1 - 0.026 14.5 0.0 0.076 13.0 0.0 1.8 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 EKE42408.1 - 0.044 12.7 0.0 0.097 11.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Peptidase_S24 PF00717.18 EKE42409.1 - 3.7e-09 36.0 0.6 6.8e-09 35.2 0.4 1.5 1 0 0 1 1 1 1 Peptidase S24-like S10_plectin PF03501.10 EKE42410.1 - 5.5e-30 103.0 0.0 8.5e-30 102.4 0.0 1.3 1 0 0 1 1 1 1 Plectin/S10 domain DBD_Tnp_Mut PF03108.10 EKE42410.1 - 0.038 13.5 0.3 0.066 12.7 0.2 1.4 1 0 0 1 1 1 0 MuDR family transposase C1_1 PF00130.17 EKE42411.1 - 0.0012 18.5 5.3 0.0026 17.4 3.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TMF_TATA_bd PF12325.3 EKE42411.1 - 0.01 15.5 8.7 0.01 15.5 6.0 3.6 3 1 0 3 3 3 1 TATA element modulatory factor 1 TATA binding Prok-RING_1 PF14446.1 EKE42411.1 - 0.018 14.7 2.2 0.038 13.7 1.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EKE42411.1 - 0.028 14.1 5.5 0.075 12.7 3.8 1.8 1 0 0 1 1 1 0 PHD-finger IncA PF04156.9 EKE42411.1 - 0.18 11.3 34.6 0.11 12.0 8.3 2.6 2 0 0 2 2 2 0 IncA protein DivIVA PF05103.8 EKE42411.1 - 1.4 8.9 31.4 1.8 8.6 10.8 3.7 2 1 0 2 2 2 0 DivIVA protein SRR PF07709.6 EKE42411.1 - 1.9 9.0 4.6 6.6 7.3 0.3 3.0 2 0 0 2 2 2 0 Seven Residue Repeat DUF2205 PF10224.4 EKE42411.1 - 2.1 8.0 19.4 0.017 14.7 3.5 4.1 3 1 1 4 4 4 0 Predicted coiled-coil protein (DUF2205) DUF342 PF03961.8 EKE42411.1 - 4.2 5.6 37.2 0.5 8.7 9.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Spc7 PF08317.6 EKE42411.1 - 5.3 5.6 34.9 0.077 11.6 4.7 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.7 EKE42411.1 - 5.5 7.0 12.1 0.58 10.0 0.8 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat RPW8 PF05659.6 EKE42411.1 - 9.3 5.7 17.0 0.041 13.4 3.1 2.9 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DnaJ PF00226.26 EKE42412.1 - 9.5e-23 79.7 3.9 1.8e-22 78.8 2.7 1.5 1 0 0 1 1 1 1 DnaJ domain Metallophos_2 PF12850.2 EKE42413.1 - 1.1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EKE42413.1 - 4e-09 36.1 0.6 1e-08 34.8 0.4 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EKE42413.1 - 0.019 14.1 0.0 0.5 9.4 0.0 2.0 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Steroid_dh PF02544.11 EKE42414.1 - 3e-41 140.6 4.9 3e-41 140.6 3.4 2.0 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EKE42414.1 - 5.4e-06 25.8 0.5 1.3e-05 24.6 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EKE42414.1 - 0.00012 22.1 0.3 0.00012 22.1 0.2 2.9 2 2 1 3 3 3 1 Phospholipid methyltransferase DUF4499 PF14934.1 EKE42414.1 - 0.039 13.8 0.5 0.15 12.0 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) Plant_vir_prot PF01307.12 EKE42414.1 - 0.12 12.0 0.8 1.5 8.6 0.0 2.7 2 1 0 2 2 2 0 Plant viral movement protein DUF2569 PF10754.4 EKE42414.1 - 0.26 11.5 7.2 0.63 10.2 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF3437 PF11919.3 EKE42415.1 - 0.00043 19.9 0.0 0.0013 18.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) VPS9 PF02204.13 EKE42419.1 - 2.6e-07 30.5 0.3 9.1e-07 28.8 0.0 2.0 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Holin_LLH PF09682.5 EKE42419.1 - 0.041 14.0 0.2 0.041 14.0 0.1 2.3 3 0 0 3 3 3 0 Phage holin protein (Holin_LLH) ChuX_HutX PF06228.8 EKE42419.1 - 0.077 12.3 0.1 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX Pyr_redox_2 PF07992.9 EKE42420.1 - 7.4e-28 97.8 0.0 2.9e-27 95.8 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKE42420.1 - 2.9e-18 66.0 3.4 1.7e-14 54.0 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKE42420.1 - 1.6e-11 43.7 0.0 1.7e-09 37.0 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EKE42420.1 - 4.7e-09 36.5 0.0 3e-05 24.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKE42420.1 - 1.1e-08 34.3 0.1 0.0017 17.3 0.1 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKE42420.1 - 7.7e-06 25.8 0.3 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKE42420.1 - 1.8e-05 23.8 0.9 0.029 13.2 0.1 3.0 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EKE42420.1 - 0.00033 20.4 0.7 0.25 11.0 0.1 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding DUF1188 PF06690.6 EKE42420.1 - 0.00041 19.5 0.2 0.0019 17.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1188) Shikimate_DH PF01488.15 EKE42420.1 - 0.00056 20.0 0.8 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EKE42420.1 - 0.0044 16.1 0.1 1.3 7.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 EKE42420.1 - 0.011 15.9 0.2 1.3 9.2 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EKE42420.1 - 0.012 14.0 9.8 1.1 7.6 0.0 4.3 3 1 2 5 5 5 0 HI0933-like protein 3HCDH_N PF02737.13 EKE42420.1 - 0.042 13.5 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 EKE42420.1 - 0.048 13.7 0.2 9.2 6.4 0.0 2.8 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Thi4 PF01946.12 EKE42420.1 - 0.1 11.6 0.4 2.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 EKE42420.1 - 0.13 11.1 2.4 0.67 8.7 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EKE42420.1 - 0.3 9.9 2.9 16 4.2 0.0 3.0 3 0 0 3 3 3 0 FAD binding domain Cofilin_ADF PF00241.15 EKE42421.1 - 3.8e-19 68.8 0.0 4.2e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein C2 PF00168.25 EKE42422.1 - 8e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 C2 domain PAGK PF15284.1 EKE42422.1 - 0.15 11.8 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Phage-encoded virulence factor LRR_5 PF13306.1 EKE42425.1 - 2.8e-40 136.9 21.2 9.8e-20 70.5 2.7 3.6 2 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42425.1 - 1.3e-17 63.3 14.5 1.6e-06 27.7 1.7 3.9 1 1 2 3 3 3 3 Leucine rich repeat VHS PF00790.14 EKE42427.1 - 0.0004 20.0 0.5 0.0015 18.1 0.1 2.1 1 1 0 1 1 1 1 VHS domain Cytochrom_NNT PF03264.9 EKE42427.1 - 0.074 12.4 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DUF676 PF05057.9 EKE42427.1 - 0.14 11.4 0.4 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Nsp1_C PF05064.8 EKE42428.1 - 0.015 14.9 0.2 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Streptin-Immun PF11083.3 EKE42428.1 - 0.093 12.7 0.5 0.2 11.6 0.2 1.7 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Carbpep_Y_N PF05388.6 EKE42428.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide BLOC1_2 PF10046.4 EKE42428.1 - 0.49 10.5 2.7 0.64 10.1 0.5 2.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RabGAP-TBC PF00566.13 EKE42429.1 - 6.7e-26 91.0 5.7 1.5e-25 89.9 3.9 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF1765 PF08578.5 EKE42431.1 - 2.2e-12 47.1 7.5 2.2e-12 47.1 5.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Memo PF01875.12 EKE42431.1 - 0.032 13.1 0.0 0.054 12.3 0.0 1.5 1 0 0 1 1 1 0 Memo-like protein Pkinase PF00069.20 EKE42432.1 - 2.3e-78 262.9 0.6 6.2e-57 192.6 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42432.1 - 2.5e-50 170.9 0.0 1.4e-34 119.3 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EKE42432.1 - 0.21 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.2 EKE42433.1 - 2e-07 30.4 5.1 7.8e-05 22.1 1.6 4.9 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE42433.1 - 3.4e-05 23.4 13.8 0.035 13.8 0.0 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EKE42433.1 - 0.0089 15.9 10.5 17 5.9 0.0 5.7 4 1 1 5 5 5 2 Leucine Rich Repeat Aminotran_1_2 PF00155.16 EKE42435.1 - 4.3e-34 118.0 0.0 5.2e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EKE42435.1 - 1.2e-05 23.8 0.0 1.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EKE42435.1 - 0.00058 19.0 0.0 0.00086 18.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EKE42435.1 - 0.00071 18.4 0.0 0.016 13.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_3 PF00202.16 EKE42435.1 - 0.00079 18.3 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Ded_cyto PF06920.8 EKE42436.1 - 4.6e-26 91.1 2.1 4.6e-26 91.1 1.5 2.8 2 0 0 2 2 2 1 Dedicator of cytokinesis FtsJ PF01728.14 EKE42437.1 - 8.3e-59 198.6 0.0 9.7e-59 198.3 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP13 PF06460.7 EKE42437.1 - 0.0029 16.5 0.1 0.0039 16.1 0.1 1.2 1 0 0 1 1 1 1 Coronavirus NSP13 Methyltransf_31 PF13847.1 EKE42437.1 - 0.016 14.7 0.0 0.47 10.0 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain CbiA PF01656.18 EKE42437.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ubie_methyltran PF01209.13 EKE42437.1 - 0.063 12.3 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EKE42437.1 - 0.087 13.4 0.0 4.9 7.7 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain TLD PF07534.11 EKE42438.1 - 0.031 14.2 0.6 0.031 14.2 0.4 1.9 2 1 0 2 2 2 0 TLD G-patch PF01585.18 EKE42440.1 - 1.5e-07 31.1 1.1 2.9e-07 30.1 0.8 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EKE42440.1 - 7.7e-06 25.6 0.1 2e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site DXPR_C PF13288.1 EKE42440.1 - 0.4 10.6 3.5 5.6 7.0 0.2 3.3 2 1 1 3 3 3 0 DXP reductoisomerase C-terminal domain PRCC PF10253.4 EKE42440.1 - 1.4 9.5 5.6 0.46 11.1 1.8 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting RasGEF PF00617.14 EKE42441.1 - 1.9e-29 102.7 1.2 7e-29 100.8 0.8 2.1 1 0 0 1 1 1 1 RasGEF domain Pox_G5 PF04599.7 EKE42442.1 - 0.0017 17.1 0.4 0.0021 16.8 0.2 1.1 1 0 0 1 1 1 1 Poxvirus G5 protein Tetraspannin PF00335.15 EKE42443.1 - 8e-10 38.3 19.3 1.2e-09 37.8 13.4 1.2 1 0 0 1 1 1 1 Tetraspanin family ATPase_gene1 PF09527.5 EKE42443.1 - 0.011 15.5 0.8 0.011 15.5 0.5 2.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) TRAP-gamma PF07074.7 EKE42443.1 - 0.014 14.9 3.4 0.028 13.9 2.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Adeno_E3_14_5 PF04834.7 EKE42443.1 - 0.15 12.5 0.4 0.15 12.5 0.3 2.8 2 1 1 3 3 3 0 Early E3 14.5 kDa protein Neurensin PF14927.1 EKE42443.1 - 0.15 11.4 3.8 0.56 9.5 0.6 2.4 2 0 0 2 2 2 0 Neurensin WD40 PF00400.27 EKE42444.1 - 1.5e-26 91.2 21.2 1.9e-10 40.2 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat I_LWEQ PF01608.12 EKE42444.1 - 0.11 12.3 2.8 0.3 11.0 1.9 1.7 1 0 0 1 1 1 0 I/LWEQ domain zf-C4H2 PF10146.4 EKE42444.1 - 0.13 12.3 8.3 0.2 11.6 5.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein ADIP PF11559.3 EKE42444.1 - 0.23 11.3 16.4 0.85 9.5 2.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EKE42444.1 - 0.24 11.3 17.6 1.4 8.9 7.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EKE42444.1 - 0.85 7.4 7.6 1.1 6.9 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EKE42444.1 - 2.2 8.0 19.1 0.059 13.1 8.9 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EKE42444.1 - 3 7.6 16.5 7.5 6.4 11.4 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 EKE42444.1 - 7.5 6.9 14.2 0.51 10.7 3.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Thioredoxin PF00085.15 EKE42445.1 - 2.9e-08 33.3 0.1 1.9e-06 27.4 0.0 3.4 4 0 0 4 4 4 1 Thioredoxin Tap-RNA_bind PF09162.5 EKE42445.1 - 0.058 12.9 1.8 1.4 8.5 0.0 3.1 3 0 0 3 3 3 0 Tap, RNA-binding DDOST_48kD PF03345.9 EKE42446.1 - 2.3e-79 266.8 10.6 2.6e-79 266.7 7.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ABC_transp_aux PF09822.4 EKE42446.1 - 0.063 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 ABC-type uncharacterized transport system ArfGap PF01412.13 EKE42447.1 - 1.1e-32 112.2 0.4 1.1e-32 112.2 0.3 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Mucin PF01456.12 EKE42447.1 - 0.00088 19.0 1.7 0.0013 18.5 1.2 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DZR PF12773.2 EKE42447.1 - 0.042 13.6 0.4 0.11 12.3 0.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EKE42447.1 - 0.36 10.9 2.8 14 5.8 0.0 3.2 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zinc_ribbon_2 PF13240.1 EKE42447.1 - 4.1 7.0 6.2 1.4 8.5 1.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.13 EKE42447.1 - 9 5.5 7.8 3.9 6.6 0.1 3.1 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others FolB PF02152.13 EKE42448.1 - 0.002 18.2 2.9 0.01 16.0 0.5 2.9 2 0 0 2 2 2 1 Dihydroneopterin aldolase PNK3P PF08645.6 EKE42448.1 - 0.39 10.1 8.3 0.098 12.0 0.4 3.1 3 0 0 3 3 3 0 Polynucleotide kinase 3 phosphatase RrnaAD PF00398.15 EKE42449.1 - 1.5e-59 201.1 0.0 1.9e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EKE42449.1 - 2.6e-11 43.5 0.0 5.2e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKE42449.1 - 1.6e-06 27.7 0.0 5.8e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE42449.1 - 1.8e-06 28.4 0.0 3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKE42449.1 - 0.00037 20.9 0.0 0.0011 19.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKE42449.1 - 0.001 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE42449.1 - 0.0011 18.3 0.0 0.0028 17.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EKE42449.1 - 0.0012 19.1 0.0 0.0038 17.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 EKE42449.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 EKE42449.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 EKE42449.1 - 0.0021 17.0 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase UPF0020 PF01170.13 EKE42449.1 - 0.0046 16.5 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 ARID PF01388.16 EKE42449.1 - 0.012 15.4 0.0 0.31 10.9 0.0 2.9 3 1 0 3 3 3 0 ARID/BRIGHT DNA binding domain Methyltransf_4 PF02390.12 EKE42449.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PRMT5 PF05185.11 EKE42449.1 - 0.051 12.4 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 EKE42449.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 EKE42449.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_28 PF02636.12 EKE42449.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SMK-1 PF04802.10 EKE42450.1 - 4.3e-09 36.1 7.4 4.3e-09 36.1 5.1 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 CAT_RBD PF03123.10 EKE42450.1 - 0.35 10.6 7.1 0.046 13.4 0.8 2.6 3 0 0 3 3 3 0 CAT RNA binding domain DUF3595 PF12166.3 EKE42451.1 - 2.2e-69 234.3 2.5 7.5e-69 232.5 1.7 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) SH3_2 PF07653.12 EKE42451.1 - 0.0027 17.1 0.0 0.0057 16.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Wzy_C PF04932.10 EKE42451.1 - 0.0056 16.4 0.5 0.0056 16.4 0.3 8.8 7 1 0 7 7 7 2 O-Antigen ligase Orbi_NS3 PF01616.11 EKE42451.1 - 0.008 15.1 0.3 0.047 12.6 0.2 2.4 1 0 0 1 1 1 1 Orbivirus NS3 PBP1_TM PF14812.1 EKE42451.1 - 0.84 9.9 9.6 0.68 10.2 0.0 3.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arf PF00025.16 EKE42452.1 - 2.2e-61 206.0 0.2 2.5e-61 205.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EKE42452.1 - 1.5e-12 47.2 0.1 1.6e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42452.1 - 5.4e-11 43.0 0.0 9.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EKE42452.1 - 5.1e-09 35.3 2.1 1.1e-07 30.9 0.0 2.8 1 1 2 3 3 3 1 G-protein alpha subunit SRPRB PF09439.5 EKE42452.1 - 7.7e-09 35.0 0.0 9.4e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE42452.1 - 1e-08 34.6 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE42452.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE42452.1 - 0.0015 17.9 0.1 0.0086 15.5 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EKE42452.1 - 0.011 14.5 0.2 0.028 13.2 0.1 1.6 1 1 1 2 2 2 0 ArgK protein AAA_14 PF13173.1 EKE42452.1 - 0.042 13.7 0.4 0.26 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EKE42452.1 - 0.064 13.5 1.5 0.37 11.0 1.0 1.9 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.20 EKE42453.1 - 7.3e-82 274.4 0.0 9.7e-82 273.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42453.1 - 4e-49 167.0 0.3 1.1e-48 165.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase C2 PF00168.25 EKE42453.1 - 1.8e-08 34.1 0.3 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.1 EKE42453.1 - 0.00014 20.9 0.0 0.0028 16.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EKE42453.1 - 0.0038 16.9 0.0 0.26 10.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4217 PF13959.1 EKE42455.1 - 1.2e-11 44.0 0.1 2.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EKE42455.1 - 0.0076 16.0 0.1 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE42455.1 - 0.011 15.2 1.0 0.46 9.9 0.0 3.0 3 1 0 3 3 3 0 DEAD/DEAH box helicase KilA-N PF04383.8 EKE42455.1 - 0.045 13.3 1.1 0.17 11.5 0.0 2.5 2 0 0 2 2 2 0 KilA-N domain K-box PF01486.12 EKE42455.1 - 6.8 6.5 11.2 0.18 11.5 0.9 2.9 3 0 0 3 3 3 0 K-box region Ras PF00071.17 EKE42456.1 - 1.9e-50 170.3 1.1 3e-50 169.7 0.7 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42456.1 - 6.1e-16 58.9 0.2 6.1e-16 58.9 0.1 2.2 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE42456.1 - 2.3e-13 49.7 0.2 5.1e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE42456.1 - 6.4e-05 22.2 0.4 0.00015 21.0 0.3 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE42456.1 - 0.00024 20.3 0.1 0.00024 20.3 0.1 2.4 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE42456.1 - 0.00093 19.1 0.1 0.0036 17.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKE42456.1 - 0.0016 18.6 0.1 0.0064 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKE42456.1 - 0.0048 16.0 0.1 0.011 14.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE42456.1 - 0.0068 16.4 0.0 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 EKE42456.1 - 0.012 15.1 0.4 0.52 9.7 0.0 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 EKE42456.1 - 0.028 14.6 0.0 0.15 12.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKE42456.1 - 0.031 13.9 0.1 0.031 13.9 0.1 2.7 2 2 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 EKE42456.1 - 0.038 13.5 0.0 0.038 13.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EKE42456.1 - 0.064 12.6 0.1 1.8 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_32 PF13654.1 EKE42456.1 - 0.4 9.2 0.0 0.4 9.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 EKE42457.1 - 0.0033 17.3 3.0 0.0065 16.3 2.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YqgF PF14639.1 EKE42457.1 - 0.08 12.5 1.3 0.13 11.7 0.8 1.4 1 1 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 HOOK PF05622.7 EKE42457.1 - 0.084 10.6 2.6 0.1 10.3 1.8 1.1 1 0 0 1 1 1 0 HOOK protein DUF4528 PF15031.1 EKE42457.1 - 0.097 12.4 0.3 0.14 11.8 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4528) Cortex-I_coil PF09304.5 EKE42457.1 - 0.2 11.6 1.6 0.34 10.9 1.1 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Pkinase PF00069.20 EKE42458.1 - 4.2e-75 252.2 0.0 6.5e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42458.1 - 3e-34 118.2 0.0 4.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EKE42458.1 - 0.00016 22.0 4.4 0.00038 20.9 3.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EKE42458.1 - 0.001 18.1 0.0 0.0023 16.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EKE42458.1 - 0.0018 17.6 0.0 0.0018 17.6 0.0 2.3 3 1 0 3 3 3 1 RIO1 family Kdo PF06293.9 EKE42458.1 - 0.0055 15.7 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE42458.1 - 0.053 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NHL PF01436.16 EKE42459.1 - 2.6e-13 49.2 0.7 0.00021 21.0 0.0 5.6 6 0 0 6 6 6 2 NHL repeat SGL PF08450.7 EKE42459.1 - 0.0051 16.2 0.0 0.11 11.8 0.0 2.5 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 EKE42459.1 - 0.41 10.4 4.2 2.4 8.0 0.6 2.7 2 0 0 2 2 2 0 Beta-propeller repeat DSPc PF00782.15 EKE42462.1 - 9.5e-29 99.6 0.2 9.5e-29 99.6 0.1 2.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 EKE42462.1 - 2e-05 24.2 41.7 0.0076 15.9 3.5 5.7 2 2 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 EKE42462.1 - 4.6e-05 22.8 42.3 0.49 10.6 0.3 9.5 6 1 1 7 7 7 2 Leucine Rich Repeat Y_phosphatase PF00102.22 EKE42462.1 - 9.8e-05 21.7 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_4 PF12799.2 EKE42462.1 - 0.00032 20.2 50.3 0.0014 18.2 3.9 6.4 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) Y_phosphatase3 PF13350.1 EKE42462.1 - 0.028 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family LRR_6 PF13516.1 EKE42462.1 - 0.03 14.3 0.4 0.03 14.3 0.3 8.5 7 2 2 9 9 9 0 Leucine Rich repeat DUF4517 PF15006.1 EKE42462.1 - 0.13 12.1 1.2 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4517) LRR_7 PF13504.1 EKE42462.1 - 0.38 11.1 39.0 2.4 8.7 0.1 10.3 12 0 0 12 12 12 0 Leucine rich repeat Ribosomal_L30 PF00327.15 EKE42464.1 - 7.8e-05 22.1 0.2 7.8e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e YlaC PF10777.4 EKE42464.1 - 0.66 9.5 5.7 3.9 7.0 3.0 2.3 2 0 0 2 2 2 0 Inner membrane protein YlaC MOZ_SAS PF01853.13 EKE42465.1 - 5.6e-71 237.6 0.5 9.9e-71 236.8 0.4 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EKE42465.1 - 6.3e-17 61.0 2.1 1.4e-16 59.9 1.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EKE42465.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKE42465.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 EKE42465.1 - 0.03 14.4 0.0 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1918 PF08940.6 EKE42465.1 - 0.17 11.2 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Peptidase_S74 PF13884.1 EKE42466.1 - 3.3e-16 59.1 0.2 1.1e-15 57.4 0.1 1.9 2 0 0 2 2 2 1 Chaperone of endosialidase HELP PF03451.9 EKE42467.1 - 0.032 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 HELP motif DUF1911 PF08929.5 EKE42467.1 - 0.062 14.0 0.3 0.1 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) NPL4 PF05021.10 EKE42468.1 - 8.4e-37 126.9 2.4 1.6e-36 126.0 1.6 1.5 1 0 0 1 1 1 1 NPL4 family DUF4186 PF13811.1 EKE42468.1 - 9.5 5.9 9.2 17 5.1 5.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4186) RRM_6 PF14259.1 EKE42469.1 - 4.4e-10 39.4 0.1 7.9e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE42469.1 - 1.3e-07 31.1 0.3 2.6e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42469.1 - 0.00032 20.4 0.1 0.0007 19.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKE42469.1 - 0.0067 16.2 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif RWP-RK PF02042.10 EKE42470.1 - 1.3e-14 53.7 0.2 2.1e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.12 EKE42470.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_AsnC-type PF13404.1 EKE42470.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.7 EKE42470.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EKE42470.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Ras PF00071.17 EKE42471.1 - 1.2e-58 197.0 0.1 1.4e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42471.1 - 9.2e-26 90.6 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42471.1 - 8.4e-12 44.6 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE42471.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE42471.1 - 4.7e-06 25.9 0.0 5.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE42471.1 - 3.2e-05 23.8 0.0 6.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE42471.1 - 0.011 15.0 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B CPT PF07931.7 EKE42471.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein S1 PF00575.18 EKE42472.1 - 0.034 14.2 0.4 0.034 14.2 0.3 3.0 3 1 1 4 4 4 0 S1 RNA binding domain ResIII PF04851.10 EKE42473.1 - 1.1e-18 67.7 0.2 3.9e-18 65.9 0.1 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EKE42473.1 - 2.2e-14 52.9 1.2 2.7e-14 52.6 0.2 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C_3 PF13625.1 EKE42473.1 - 2.2e-12 46.8 0.0 3.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.26 EKE42473.1 - 6.9e-12 45.0 0.0 2.2e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKE42473.1 - 5.9e-07 29.1 0.2 1.3e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Rep_fac_C PF08542.6 EKE42473.1 - 0.18 11.8 5.4 0.12 12.4 1.1 2.5 2 0 0 2 2 2 0 Replication factor C C-terminal domain LIM PF00412.17 EKE42474.1 - 0.12 12.5 6.2 0.46 10.5 4.3 2.0 1 0 0 1 1 1 0 LIM domain Rhodanese PF00581.15 EKE42475.1 - 2.7e-07 30.9 0.0 3.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain RasGEF PF00617.14 EKE42476.1 - 3.7e-39 134.3 0.7 7.6e-39 133.3 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKE42476.1 - 7e-13 48.5 0.1 5.1e-12 45.8 0.0 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif Metallophos PF00149.23 EKE42477.1 - 2.9e-16 59.4 0.9 5.2e-16 58.6 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE42477.1 - 3.5e-13 49.6 0.3 5.4e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1758 PF05585.7 EKE42477.1 - 0.033 13.7 0.4 0.07 12.6 0.3 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Metallophos_3 PF14582.1 EKE42477.1 - 0.12 11.4 0.0 0.46 9.6 0.1 1.9 2 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Neurensin PF14927.1 EKE42478.1 - 0.035 13.4 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Neurensin DUF1561 PF07598.6 EKE42478.1 - 0.079 10.8 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) DUF4097 PF13349.1 EKE42478.1 - 0.28 10.7 3.2 1.7 8.2 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4097) Acetyltransf_1 PF00583.19 EKE42479.1 - 1.8e-11 43.8 0.0 3.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKE42479.1 - 4.1e-07 30.0 0.2 8.3e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKE42479.1 - 4.7e-06 26.6 2.1 1.1e-05 25.4 1.4 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKE42479.1 - 1.2e-05 25.3 0.0 2.2e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE42479.1 - 3.2e-05 23.7 0.0 4.9e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKE42479.1 - 0.0032 17.6 0.1 0.0052 16.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1792 PF08759.6 EKE42479.1 - 0.032 13.8 1.0 0.047 13.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) MCM PF00493.18 EKE42480.1 - 4.5e-128 426.7 0.0 6.1e-128 426.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKE42480.1 - 1.7e-10 41.4 3.7 2.2e-09 37.8 1.0 3.4 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EKE42480.1 - 2.1e-08 33.9 0.1 1.2e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EKE42480.1 - 6.8e-08 31.9 0.3 6.2e-05 22.2 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKE42480.1 - 0.00056 19.5 0.1 0.018 14.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKE42480.1 - 0.0082 15.6 0.3 0.67 9.4 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain Zn-ribbon_8 PF09723.5 EKE42480.1 - 0.029 14.3 0.2 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain AAA_32 PF13654.1 EKE42480.1 - 0.044 12.4 0.2 0.09 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase_2 PF13335.1 EKE42480.1 - 0.065 13.6 1.2 0.14 12.5 0.3 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF1357 PF07094.6 EKE42480.1 - 0.23 10.8 1.9 0.24 10.8 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1357) F-box PF00646.28 EKE42481.1 - 7.7e-07 28.6 0.4 2.3e-06 27.0 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKE42481.1 - 4.3e-05 23.1 0.1 0.00016 21.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like PIG-P PF08510.7 EKE42482.1 - 0.034 13.7 1.1 0.07 12.7 0.7 1.5 1 0 0 1 1 1 0 PIG-P EF-hand_1 PF00036.27 EKE42484.1 - 4e-15 53.8 0.1 2.2e-06 26.5 0.4 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EKE42484.1 - 3.2e-10 40.0 0.1 2.8e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE42484.1 - 4.5e-10 38.5 0.0 0.081 12.8 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EKE42484.1 - 9.3e-08 31.0 0.0 0.04 13.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EKE42484.1 - 7.9e-07 28.6 0.1 4.8e-05 22.8 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain pair START PF01852.14 EKE42485.1 - 2e-16 59.9 0.1 2.2e-16 59.8 0.1 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EKE42485.1 - 0.002 17.7 0.2 0.0034 17.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Polyketide_cyc2 PF10604.4 EKE42485.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RasGAP PF00616.14 EKE42489.1 - 4.4e-25 88.5 3.5 4.4e-25 88.5 2.4 2.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Ank_4 PF13637.1 EKE42489.1 - 1.8e-21 76.0 2.4 7.2e-10 39.1 0.1 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE42489.1 - 9.6e-20 70.7 2.0 5.9e-08 32.9 0.0 3.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EKE42489.1 - 6.4e-15 54.1 1.7 0.00084 19.0 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EKE42489.1 - 3.8e-14 52.3 0.4 6.2e-07 29.4 0.0 4.5 2 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE42489.1 - 5.1e-12 44.7 4.1 0.026 14.7 0.1 5.1 4 0 0 4 4 4 3 Ankyrin repeat Tachylectin PF14517.1 EKE42490.1 - 0.034 13.4 1.3 0.042 13.1 0.2 1.6 2 0 0 2 2 2 0 Tachylectin BSMAP PF12280.3 EKE42491.1 - 1.3 8.8 5.5 2.3 8.0 3.8 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein CDC45 PF02724.9 EKE42491.1 - 4 5.3 15.5 6.7 4.6 10.7 1.3 1 0 0 1 1 1 0 CDC45-like protein VSG_B PF13206.1 EKE42491.1 - 9.8 5.1 26.5 2.5 7.1 0.2 2.1 2 0 0 2 2 2 0 Trypanosomal VSG domain RNA_pol_Rpb1_3 PF04983.13 EKE42492.1 - 0.1 12.2 1.9 0.14 11.8 0.8 1.7 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 3 Pkinase PF00069.20 EKE42493.1 - 1e-11 44.4 5.6 1.1e-11 44.3 1.7 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42493.1 - 1.6e-11 43.7 1.5 4.7e-11 42.2 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pex24p PF06398.6 EKE42495.1 - 0.00072 18.4 0.4 0.00072 18.4 0.3 2.2 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin VirB3 PF05101.8 EKE42495.1 - 9.9 6.2 6.3 0.86 9.6 0.1 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein RhoGAP PF00620.22 EKE42496.1 - 1.3e-36 125.5 0.0 2.8e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain BSP_II PF05432.6 EKE42496.1 - 0.11 11.7 6.8 0.19 11.0 4.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Arm PF00514.18 EKE42497.1 - 0.059 13.2 6.2 3.1 7.7 0.3 4.8 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat ParcG PF10274.4 EKE42497.1 - 0.099 12.5 3.6 3.5 7.5 0.1 2.9 2 1 1 3 3 3 0 Parkin co-regulated protein MA3 PF02847.12 EKE42499.1 - 1.3e-14 53.8 2.3 2.5e-14 52.9 0.1 2.6 3 0 0 3 3 3 1 MA3 domain MIF4G PF02854.14 EKE42499.1 - 1.5e-07 31.0 1.8 4.3e-05 23.0 1.0 2.5 2 0 0 2 2 2 2 MIF4G domain Endonuc-MspI PF09208.5 EKE42499.1 - 0.0051 15.9 0.4 0.0096 15.0 0.3 1.4 1 0 0 1 1 1 1 Restriction endonuclease MspI RRM_1 PF00076.17 EKE42500.1 - 0.032 13.8 0.3 0.96 9.1 0.0 2.4 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42500.1 - 0.069 13.0 0.2 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Actin PF00022.14 EKE42501.1 - 3.8e-89 298.8 0.0 4.7e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKE42501.1 - 0.0093 14.6 0.0 3.2 6.2 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein TLD PF07534.11 EKE42502.1 - 0.00096 19.1 0.3 0.0017 18.3 0.2 1.5 1 1 0 1 1 1 1 TLD RNA_pol_Rpb2_6 PF00562.23 EKE42503.1 - 4.3e-110 368.0 0.2 8.7e-110 367.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EKE42503.1 - 3.4e-29 101.2 0.2 4.9e-29 100.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EKE42503.1 - 6.9e-22 76.9 0.0 1.5e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EKE42503.1 - 1.3e-20 73.4 0.0 3.1e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EKE42503.1 - 5.8e-10 38.9 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EKE42503.1 - 5.5e-08 32.6 0.1 1.3e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain LpxC PF03331.8 EKE42503.1 - 0.067 12.1 0.1 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase Zn-ribbon_8 PF09723.5 EKE42503.1 - 0.18 11.7 7.5 0.43 10.5 5.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain PHD PF00628.24 EKE42505.1 - 4.2e-11 42.3 30.2 9.6e-08 31.6 11.0 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 EKE42505.1 - 1.4e-07 31.5 23.4 1.7e-07 31.2 1.4 2.6 2 1 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EKE42505.1 - 3.2e-07 30.3 15.0 2.2e-05 24.4 1.0 2.3 2 0 0 2 2 2 2 PHD-zinc-finger like domain Mago_nashi PF02792.9 EKE42506.1 - 7.5e-42 142.4 2.8 9e-42 142.1 2.0 1.0 1 0 0 1 1 1 1 Mago nashi protein C9orf72-like PF15019.1 EKE42506.1 - 0.013 14.7 0.7 0.015 14.5 0.5 1.2 1 0 0 1 1 1 0 C9orf72-like protein family CECR6_TMEM121 PF14997.1 EKE42507.1 - 0.0079 15.8 1.3 0.0095 15.5 0.9 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family Mem_trans PF03547.13 EKE42507.1 - 0.99 7.6 5.0 0.32 9.2 1.6 1.5 1 1 1 2 2 2 0 Membrane transport protein DUF4131 PF13567.1 EKE42507.1 - 1.8 7.9 5.5 0.42 9.9 1.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4199 PF13858.1 EKE42507.1 - 2.2 8.1 5.7 0.23 11.3 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) zf-LITAF-like PF10601.4 EKE42507.1 - 2.7 7.9 5.1 7.3 6.5 0.1 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain HTH_23 PF13384.1 EKE42508.1 - 2.5e-05 23.7 0.1 5.2e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EKE42508.1 - 0.00019 21.5 0.8 0.0056 16.8 0.1 2.9 1 1 2 3 3 3 2 Winged helix-turn helix HTH_28 PF13518.1 EKE42508.1 - 0.00064 19.6 1.3 0.0043 17.0 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EKE42508.1 - 0.0051 16.3 1.0 0.013 15.0 0.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Myb_DNA-binding PF00249.26 EKE42508.1 - 0.034 14.1 0.2 0.47 10.5 0.0 2.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain HTH_37 PF13744.1 EKE42508.1 - 0.058 13.2 0.3 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3782 PF12644.2 EKE42508.1 - 0.084 12.6 0.7 0.21 11.4 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Ribosomal_L22 PF00237.14 EKE42508.1 - 0.088 12.7 1.0 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e HTH_32 PF13565.1 EKE42508.1 - 1.1 10.1 4.4 0.66 10.8 0.3 2.5 2 1 1 3 3 3 0 Homeodomain-like domain zf-H2C2_5 PF13909.1 EKE42509.1 - 0.0037 17.3 7.0 0.0037 17.3 4.9 3.6 3 2 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EKE42509.1 - 0.054 13.8 29.1 0.35 11.3 4.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 EKE42509.1 - 0.21 11.8 18.7 0.45 10.7 3.9 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EKE42509.1 - 0.92 9.2 9.5 0.68 9.6 3.0 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_7 PF15269.1 EKE42509.1 - 3.9 7.4 14.4 6 6.8 4.3 2.4 2 1 0 2 2 2 0 Zinc-finger zf-C2H2 PF00096.21 EKE42509.1 - 7.1 7.1 30.9 0.78 10.2 4.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type CBFD_NFYB_HMF PF00808.18 EKE42512.1 - 1.1e-12 47.8 0.2 1.6e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKE42512.1 - 1.9e-06 27.8 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EKE42512.1 - 0.017 14.9 0.2 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TAF PF02969.12 EKE42512.1 - 0.027 14.4 0.2 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TAF4 PF05236.9 EKE42512.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family LSM PF01423.17 EKE42513.1 - 2.9e-14 52.3 1.3 3.4e-14 52.1 0.9 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 EKE42513.1 - 0.024 14.3 0.2 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain LRR_5 PF13306.1 EKE42514.1 - 0.0032 17.1 3.0 0.0032 17.1 2.1 12.6 5 3 7 13 13 13 10 Leucine rich repeats (6 copies) MFS_1 PF07690.11 EKE42516.1 - 0.00043 19.1 1.3 0.00076 18.3 0.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2512 PF10710.4 EKE42516.1 - 0.0032 16.9 5.5 0.0032 16.9 3.8 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2512) DUF2189 PF09955.4 EKE42516.1 - 0.014 15.3 0.2 0.2 11.6 0.0 2.5 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) DUF1449 PF07290.6 EKE42517.1 - 0.17 11.2 2.1 0.3 10.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1449) PLDc PF00614.17 EKE42518.1 - 6.5e-17 60.7 0.6 4e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EKE42518.1 - 2.1e-14 53.3 4.6 5.1e-08 32.7 1.4 2.9 2 1 0 2 2 2 2 PLD-like domain Vps51 PF08700.6 EKE42519.1 - 4.8e-12 45.5 0.7 4.8e-12 45.5 0.5 3.1 4 0 0 4 4 4 1 Vps51/Vps67 Sec5 PF15469.1 EKE42519.1 - 7.5e-11 42.0 4.2 7.5e-11 42.0 2.9 2.8 4 0 0 4 4 4 1 Exocyst complex component Sec5 Dor1 PF04124.7 EKE42519.1 - 7.6e-10 37.7 3.4 1.4e-09 36.8 2.4 1.4 1 0 0 1 1 1 1 Dor1-like family V_ATPase_I PF01496.14 EKE42519.1 - 0.00017 19.6 4.0 0.0023 15.8 1.3 2.1 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EKE42519.1 - 0.0023 17.7 0.7 0.0023 17.7 0.5 4.4 5 1 1 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.4 EKE42519.1 - 0.011 15.7 7.1 0.034 14.1 2.6 3.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 CENP-H PF05837.7 EKE42519.1 - 0.022 14.9 3.0 0.15 12.2 0.3 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) COG2 PF06148.6 EKE42519.1 - 0.025 14.4 8.8 0.045 13.6 1.2 3.7 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 EKE42519.1 - 0.057 12.5 5.3 0.11 11.6 0.4 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TACC PF05010.9 EKE42519.1 - 0.072 12.8 11.5 0.59 9.8 7.9 2.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF2408 PF10303.4 EKE42519.1 - 0.084 12.9 3.9 0.22 11.6 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4201 PF13870.1 EKE42519.1 - 0.32 10.3 10.2 0.033 13.6 2.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Laminin_II PF06009.7 EKE42519.1 - 0.37 10.5 7.2 1.5 8.5 0.8 3.8 3 1 1 4 4 4 0 Laminin Domain II NPV_P10 PF05531.7 EKE42519.1 - 0.68 10.2 5.6 1.9 8.7 0.3 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 EKE42519.1 - 3.2 8.2 6.7 4.4 7.7 0.8 3.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 EKE42519.1 - 7 6.4 10.8 0.28 10.9 0.2 3.7 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) Ribosomal_L36e PF01158.13 EKE42520.1 - 2.7e-26 91.3 3.3 3.3e-26 91.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e DUF531 PF04407.7 EKE42520.1 - 0.012 15.5 0.4 2.3 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF531) Propeptide_C1 PF08127.8 EKE42520.1 - 0.045 13.3 0.4 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C1 propeptide CLTH PF10607.4 EKE42520.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.4 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain CybS PF05328.7 EKE42522.1 - 9.7 5.8 7.9 11 5.5 0.1 2.8 3 0 0 3 3 3 0 CybS SHS2_Rpb7-N PF03876.12 EKE42523.1 - 0.00091 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PseudoU_synth_2 PF00849.17 EKE42524.1 - 1e-28 100.2 0.0 2e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase GTF2I PF02946.9 EKE42524.1 - 0.072 12.9 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 GTF2I-like repeat DOCK-C2 PF14429.1 EKE42526.1 - 1.4e-49 168.2 1.6 3.3e-49 167.0 1.1 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins RRN7 PF11781.3 EKE42526.1 - 0.044 13.2 0.4 0.13 11.7 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_S5 PF00333.15 EKE42527.1 - 6.3e-26 89.9 2.0 1.2e-25 88.9 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EKE42527.1 - 1.6e-23 81.7 0.0 3.7e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WD40 PF00400.27 EKE42528.1 - 9.6e-19 66.5 5.3 0.002 17.9 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EKE42528.1 - 1.8e-07 30.9 0.1 1.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex CemA PF03040.9 EKE42528.1 - 0.11 12.0 0.8 0.21 11.1 0.6 1.4 1 0 0 1 1 1 0 CemA family Ribosomal_L15e PF00827.12 EKE42529.1 - 6.6e-78 260.6 5.4 7.7e-78 260.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 ADK PF00406.17 EKE42530.1 - 1.7e-44 151.3 0.0 2e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EKE42530.1 - 2.8e-09 37.3 0.0 4.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKE42530.1 - 1.1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE42530.1 - 7.9e-06 26.6 0.0 1.4e-05 25.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EKE42530.1 - 0.00013 21.3 0.4 0.16 11.3 0.0 2.1 1 1 1 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 EKE42530.1 - 0.0018 18.4 0.0 0.0036 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EKE42530.1 - 0.0055 16.4 0.5 0.019 14.6 0.2 2.1 1 1 1 2 2 2 1 NTPase dNK PF01712.14 EKE42530.1 - 0.03 14.2 0.1 0.064 13.1 0.0 1.5 1 1 0 1 1 1 0 Deoxynucleoside kinase Zeta_toxin PF06414.7 EKE42530.1 - 0.095 11.7 0.1 0.23 10.5 0.1 1.8 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.24 EKE42530.1 - 0.12 12.6 0.9 0.71 10.0 0.6 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EKE42530.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AMMECR1 PF01871.12 EKE42531.1 - 9.7e-41 138.7 0.0 1.1e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Iso_dh PF00180.15 EKE42532.1 - 8.5e-85 284.7 0.0 1e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-SAP30 PF13866.1 EKE42532.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger PC_rep PF01851.17 EKE42534.1 - 9.7e-11 41.2 22.5 0.0014 18.7 0.1 7.7 8 0 0 8 8 8 3 Proteasome/cyclosome repeat CD20 PF04103.10 EKE42535.1 - 0.0027 17.6 4.6 0.004 17.0 3.2 1.3 1 0 0 1 1 1 1 CD20-like family EMP70 PF02990.11 EKE42535.1 - 0.023 13.1 1.1 0.04 12.3 0.8 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 DUF4064 PF13273.1 EKE42535.1 - 0.99 9.5 11.3 6.3 6.9 4.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Tetraspannin PF00335.15 EKE42535.1 - 6.2 6.0 17.9 14 4.8 12.4 1.7 1 1 0 1 1 1 0 Tetraspanin family Sod_Fe_N PF00081.17 EKE42536.1 - 3.5 7.9 8.4 0.1 12.8 0.7 2.3 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Myb_DNA-binding PF00249.26 EKE42537.1 - 5e-11 42.4 0.0 7.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE42537.1 - 7.4e-05 22.7 0.6 0.001 19.1 0.1 2.3 1 1 2 3 3 3 1 Myb-like DNA-binding domain ATP-synt_E_2 PF08112.6 EKE42537.1 - 0.092 12.8 3.1 0.46 10.5 1.7 2.2 1 1 1 2 2 2 0 ATP synthase epsilon subunit Phage_pRha PF09669.5 EKE42537.1 - 0.84 10.0 6.3 0.11 12.8 1.2 1.8 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Reo_sigmaC PF04582.7 EKE42538.1 - 4.4 6.3 62.1 0.25 10.4 4.6 7.5 1 1 6 8 8 8 0 Reovirus sigma C capsid protein Rad21_Rec8_N PF04825.8 EKE42539.1 - 2.1e-40 137.1 0.1 1.5e-39 134.3 0.0 2.2 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EKE42539.1 - 8.7e-12 44.0 0.1 4.5e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EKE42539.1 - 2.9e-06 27.0 0.0 2.9e-06 27.0 0.0 2.7 2 0 0 2 2 2 1 ScpA/B protein His_Phos_1 PF00300.17 EKE42540.1 - 6e-22 78.4 0.0 1.2e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IPK PF03770.11 EKE42540.1 - 4.1e-13 49.4 0.4 3.8e-08 33.1 0.1 2.6 2 0 0 2 2 2 2 Inositol polyphosphate kinase MIT PF04212.13 EKE42541.1 - 6.5e-18 64.3 11.6 4.1e-10 39.3 1.7 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain LIM PF00412.17 EKE42541.1 - 2e-06 27.7 1.5 4.7e-05 23.3 1.0 2.4 1 1 1 2 2 2 2 LIM domain Arrestin_C PF02752.17 EKE42541.1 - 0.022 14.8 0.2 0.022 14.8 0.1 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain TPR_12 PF13424.1 EKE42541.1 - 0.024 14.5 1.6 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EKE42541.1 - 0.024 14.3 1.1 6.5 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKE42541.1 - 0.085 12.5 6.4 2 8.1 1.1 2.7 2 1 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 EKE42541.1 - 0.5 10.0 5.9 1.4 8.6 0.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKE42541.1 - 3.7 7.6 7.6 1.8 8.6 0.9 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKE42541.1 - 5.5 7.0 5.9 4.5 7.2 0.3 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat CAMSAP_CH PF11971.3 EKE42542.1 - 3.6e-07 29.7 11.8 2.9e-05 23.6 0.0 3.9 4 0 0 4 4 4 2 CAMSAP CH domain IBR PF01485.16 EKE42543.1 - 3.5e-10 39.6 60.9 1.1e-07 31.6 10.3 4.5 2 1 2 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EKE42543.1 - 8.6e-07 28.8 9.2 8.6e-07 28.8 6.4 5.1 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE42543.1 - 1.7e-06 27.7 7.2 1.7e-06 27.7 5.0 4.5 2 1 2 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.20 EKE42543.1 - 0.00015 21.3 7.9 0.00015 21.3 5.5 5.5 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKE42543.1 - 0.013 15.1 4.7 0.013 15.1 3.3 3.9 3 0 0 3 3 3 0 RING-type zinc-finger Fe_bilin_red PF05996.7 EKE42543.1 - 0.017 14.6 1.0 0.3 10.5 0.1 2.3 2 1 0 2 2 2 0 Ferredoxin-dependent bilin reductase zf-C3HC4_4 PF15227.1 EKE42543.1 - 0.017 14.9 7.9 0.017 14.9 5.5 5.3 4 1 1 5 5 5 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EKE42543.1 - 0.028 14.1 10.1 0.028 14.1 7.0 5.5 2 1 1 4 4 4 0 zinc-RING finger domain Archease PF01951.11 EKE42544.1 - 0.054 13.4 1.1 4.2 7.3 0.2 2.2 1 1 0 2 2 2 0 Archease protein family (MTH1598/TM1083) SRI PF08236.6 EKE42545.1 - 0.034 14.0 0.5 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain RNA_pol_I_A49 PF06870.7 EKE42546.1 - 3.2e-11 42.4 0.3 4.6e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Histone PF00125.19 EKE42547.1 - 2.1e-16 59.8 0.2 2.1e-16 59.8 0.2 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKE42547.1 - 0.00014 21.8 1.3 0.00059 19.8 0.6 1.9 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EKE42547.1 - 0.0054 16.8 0.1 0.0078 16.3 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S P3A PF08727.6 EKE42547.1 - 0.041 13.2 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like BTV_NS2 PF04514.7 EKE42547.1 - 0.063 12.1 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2891 PF11199.3 EKE42547.1 - 0.082 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) TFIID_20kDa PF03847.8 EKE42547.1 - 0.092 13.0 0.3 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A PTPS PF01242.14 EKE42547.1 - 0.13 11.9 0.2 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Peptidase_C1 PF00112.18 EKE42548.1 - 1.2e-22 80.9 5.3 1.2e-22 80.9 3.7 2.8 2 1 1 3 3 3 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE42548.1 - 2.3e-07 30.9 1.7 2.3e-07 30.9 1.2 2.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) DUF1546 PF07571.8 EKE42549.1 - 2e-20 72.7 0.1 4.4e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EKE42549.1 - 4.3e-13 49.0 0.3 1.2e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EKE42549.1 - 1.6e-05 24.9 0.1 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKE42549.1 - 0.00021 21.2 0.2 0.00021 21.2 0.1 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EKE42549.1 - 0.00049 19.7 0.1 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.10 EKE42549.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EKE42549.1 - 0.24 11.5 2.0 0.43 10.7 0.0 2.4 3 0 0 3 3 3 0 Kinetochore component CENP-S Pox_VLTF3 PF04947.9 EKE42549.1 - 0.31 10.5 9.4 0.33 10.4 0.2 3.3 2 1 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like zf-C3HC4_3 PF13920.1 EKE42550.1 - 1.7e-15 56.3 7.7 2.7e-15 55.7 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE42550.1 - 7.4e-08 32.2 11.0 1.5e-07 31.2 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE42550.1 - 1.5e-05 24.6 8.6 2.6e-05 23.8 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKE42550.1 - 3.7e-05 23.4 10.5 3.7e-05 23.4 7.3 1.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.1 EKE42550.1 - 0.00049 19.5 6.5 0.00055 19.4 3.6 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EKE42550.1 - 0.0033 16.9 6.2 0.0062 16.1 4.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EKE42550.1 - 0.56 10.0 4.1 1 9.1 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.1 EKE42550.1 - 0.91 9.3 4.4 2.3 8.0 3.0 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.9 EKE42550.1 - 0.92 9.0 6.8 3.8 7.0 4.7 2.0 1 1 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 EKE42550.1 - 1.6 8.5 6.2 4.2 7.2 4.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon RecR PF02132.10 EKE42550.1 - 1.7 8.1 6.9 2.6 7.5 0.5 2.5 2 1 0 2 2 2 0 RecR protein DUF2344 PF10105.4 EKE42551.1 - 0.032 13.7 0.6 0.043 13.2 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Mnd1 PF03962.10 EKE42551.1 - 0.047 13.3 6.2 0.056 13.0 4.3 1.2 1 0 0 1 1 1 0 Mnd1 family Sec62 PF03839.11 EKE42551.1 - 0.11 11.8 1.1 0.13 11.6 0.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2624 PF11116.3 EKE42551.1 - 0.14 12.6 2.3 3.5 8.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) APG6 PF04111.7 EKE42551.1 - 0.14 11.1 8.4 0.16 11.0 5.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 EKE42551.1 - 0.2 11.3 1.8 0.24 11.0 1.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.7 EKE42551.1 - 0.42 10.4 4.9 0.66 9.7 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) COG5 PF10392.4 EKE42551.1 - 0.46 10.4 6.4 0.24 11.3 3.0 1.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Phage_GP20 PF06810.6 EKE42551.1 - 0.47 9.8 8.3 0.26 10.7 4.1 1.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 EKE42551.1 - 0.7 9.9 7.6 4.3 7.4 4.0 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EKE42551.1 - 2.1 7.8 12.6 3.2 7.2 8.6 1.3 1 1 0 1 1 1 0 IncA protein Tetraspannin PF00335.15 EKE42552.1 - 2.2e-06 27.1 23.6 5.2e-06 25.8 16.3 1.6 1 1 0 1 1 1 1 Tetraspanin family IncA PF04156.9 EKE42552.1 - 4.5 6.8 0.0 4.5 6.8 0.0 3.2 2 1 1 3 3 3 0 IncA protein DUF606 PF04657.8 EKE42552.1 - 6 6.9 17.7 3.1 7.8 3.7 3.1 2 1 1 3 3 3 0 Protein of unknown function, DUF606 PH PF00169.24 EKE42554.1 - 1e-08 35.2 0.5 1e-08 35.2 0.3 2.2 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 EKE42554.1 - 0.013 15.5 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.1 EKE42554.1 - 0.014 15.6 1.6 0.014 15.6 1.1 3.2 3 1 0 3 3 3 0 Pleckstrin homology domain CAF-1_p150 PF11600.3 EKE42554.1 - 0.039 13.3 51.0 0.064 12.6 35.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 EKE42554.1 - 0.25 9.5 31.4 0.34 9.1 21.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3523 PF12037.3 EKE42554.1 - 0.37 9.7 42.9 0.83 8.5 29.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) SH3_9 PF14604.1 EKE42556.1 - 1.9e-18 65.7 0.2 4.2e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKE42556.1 - 4.7e-18 64.3 0.1 1.2e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EKE42556.1 - 1.4e-16 60.7 2.1 2e-16 60.1 1.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EKE42556.1 - 1.9e-14 52.8 0.0 3.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TPR_MLP1_2 PF07926.7 EKE42556.1 - 0.0083 15.8 3.0 1.3 8.7 0.3 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Spatacsin_C PF14649.1 EKE42556.1 - 0.039 12.8 0.6 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Spatacsin C-terminus Vps5 PF09325.5 EKE42556.1 - 0.044 13.0 2.2 0.17 11.1 0.3 2.1 2 0 0 2 2 2 0 Vps5 C terminal like eIF3_subunit PF08597.5 EKE42556.1 - 0.047 13.2 0.1 0.047 13.2 0.1 1.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Tfb4 PF03850.9 EKE42557.1 - 1.4e-32 113.0 2.0 1.4e-32 113.0 1.4 1.2 1 1 0 1 1 1 1 Transcription factor Tfb4 Chordopox_E11 PF06138.7 EKE42557.1 - 0.022 14.8 0.4 0.037 14.1 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus E11 protein zf-C3HC4_3 PF13920.1 EKE42557.1 - 0.08 12.6 10.2 0.076 12.6 3.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.8 EKE42557.1 - 0.36 10.6 12.1 12 5.7 7.0 3.0 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type COPI_C PF06957.6 EKE42557.1 - 0.96 7.9 3.2 0.96 7.9 0.5 1.9 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus zf-C3HC4_2 PF13923.1 EKE42557.1 - 3.6 7.7 12.9 1.4 9.0 6.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.14 EKE42558.1 - 0.27 9.0 2.1 0.29 8.9 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adeno_PIX PF03955.9 EKE42558.1 - 1.3 9.5 3.5 2.2 8.8 2.4 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) SPRY PF00622.23 EKE42559.1 - 5.2e-18 65.3 0.2 1.1e-17 64.2 0.2 1.6 1 0 0 1 1 1 1 SPRY domain zf-DHHC PF01529.15 EKE42560.1 - 6.7e-34 116.7 18.8 6.7e-34 116.7 13.0 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase IncA PF04156.9 EKE42560.1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.8 2 2 0 2 2 2 0 IncA protein Spt4 PF06093.8 EKE42560.1 - 0.46 10.4 6.4 1.1 9.1 4.4 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DZR PF12773.2 EKE42560.1 - 5.3 6.9 11.3 12 5.8 7.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon Metallophos PF00149.23 EKE42561.1 - 1.1e-14 54.3 0.3 2.6e-14 53.0 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKE42561.1 - 2.7e-10 40.3 0.1 5.1e-10 39.4 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LRR_6 PF13516.1 EKE42562.1 - 0.041 13.9 0.0 0.041 13.9 0.0 12.6 15 1 1 16 16 16 0 Leucine Rich repeat LRR_4 PF12799.2 EKE42562.1 - 0.37 10.4 41.7 1.6 8.4 0.0 8.9 5 3 4 9 9 8 0 Leucine Rich repeats (2 copies) Adap_comp_sub PF00928.16 EKE42563.1 - 2.9e-49 167.5 0.0 3.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Vitellogenin_N PF01347.17 EKE42564.1 - 0.036 12.3 0.1 0.044 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region COPIIcoated_ERV PF07970.7 EKE42566.1 - 1e-58 198.6 1.1 1.5e-58 198.0 0.3 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EKE42566.1 - 6.9e-30 102.8 0.7 1.1e-28 99.0 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ribosomal_L18e PF00828.14 EKE42567.1 - 4.4e-15 56.2 0.1 6.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PDE6_gamma PF04868.7 EKE42568.1 - 0.077 12.8 0.1 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit ADP_ribosyl_GH PF03747.9 EKE42569.1 - 1.6e-39 136.4 0.0 1.9e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Fe-ADH PF00465.14 EKE42570.1 - 1.1e-71 241.4 0.0 1.3e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKE42570.1 - 4e-10 39.4 0.2 5.4e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EKE42570.1 - 0.013 14.4 0.4 1.5 7.7 0.0 2.7 2 1 0 2 2 2 0 3-dehydroquinate synthase Pkinase PF00069.20 EKE42571.1 - 1.3e-61 208.0 0.0 3.6e-61 206.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42571.1 - 7e-43 146.5 0.0 1.4e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42571.1 - 2.5e-07 29.9 0.0 1.4e-06 27.4 0.0 2.1 2 1 1 3 3 3 1 Kinase-like APH PF01636.18 EKE42571.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pepsin-I3 PF06394.8 EKE42571.1 - 0.057 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Bac_DNA_binding PF00216.16 EKE42572.1 - 0.017 15.1 0.6 0.11 12.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial DNA-binding protein Fer2_4 PF13510.1 EKE42572.1 - 0.81 9.5 4.8 8.6 6.2 0.1 3.8 3 1 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain He_PIG PF05345.7 EKE42572.1 - 1.4 8.9 12.3 7.9 6.5 0.1 3.9 2 1 0 2 2 2 0 Putative Ig domain Glyco_hydro_31 PF01055.21 EKE42573.1 - 2.3e-151 504.5 8.0 3.2e-151 504.1 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKE42573.1 - 2.6e-16 59.2 1.6 4e-16 58.6 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like RseC_MucC PF04246.7 EKE42575.1 - 0.58 9.7 2.2 0.54 9.8 0.7 1.6 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Ras PF00071.17 EKE42576.1 - 3.2e-55 185.9 1.5 3.2e-55 185.9 1.0 1.4 2 0 0 2 2 2 1 Ras family Arf PF00025.16 EKE42576.1 - 4e-18 65.2 0.8 5.3e-18 64.8 0.2 1.4 1 1 1 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EKE42576.1 - 2.3e-17 63.5 0.3 5.5e-17 62.3 0.1 1.7 2 0 0 2 2 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKE42576.1 - 6.9e-11 41.7 0.2 9.8e-11 41.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKE42576.1 - 1.4e-06 28.2 0.0 4.2e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE42576.1 - 1.4e-06 27.9 0.2 2.9e-06 26.8 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EKE42576.1 - 0.00013 21.2 0.6 0.0015 17.8 0.4 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EKE42576.1 - 0.0067 15.6 0.0 0.014 14.6 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 EKE42576.1 - 0.0098 14.9 0.2 0.0098 14.9 0.2 2.1 1 1 1 2 2 2 1 Septin PduV-EutP PF10662.4 EKE42576.1 - 0.017 14.5 0.5 0.27 10.7 0.4 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 EKE42576.1 - 0.025 13.3 7.3 0.67 8.5 5.0 2.5 1 1 0 1 1 1 0 G-protein alpha subunit DUF258 PF03193.11 EKE42576.1 - 0.027 13.6 2.0 0.29 10.3 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 DBI_PRT PF02277.12 EKE42576.1 - 0.031 13.3 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase AAA_22 PF13401.1 EKE42576.1 - 0.058 13.5 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1770 PF08589.5 EKE42576.1 - 0.09 13.3 1.9 0.2 12.2 1.3 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) NifT PF06988.6 EKE42576.1 - 0.85 9.1 7.4 0.3 10.5 0.1 2.5 2 0 0 2 2 2 0 NifT/FixU protein Trypan_PARP PF05887.6 EKE42576.1 - 7.5 6.3 11.4 16 5.2 7.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 EKE42577.1 - 4.7e-67 225.8 0.1 6.8e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42577.1 - 3.5e-49 167.2 0.0 5e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42577.1 - 7.1e-05 21.8 0.0 0.00097 18.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EKE42577.1 - 0.004 16.0 0.6 0.0077 15.1 0.4 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EKE42577.1 - 0.09 12.4 0.0 0.64 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family CH PF00307.26 EKE42578.1 - 3.5e-17 62.4 5.2 4.7e-12 45.9 0.2 2.9 2 1 1 3 3 3 2 Calponin homology (CH) domain Mod_r PF07200.8 EKE42579.1 - 0.28 11.0 27.3 0.042 13.7 2.0 3.5 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein RmuC PF02646.11 EKE42579.1 - 0.32 9.8 21.5 0.32 9.7 3.8 3.2 3 0 0 3 3 3 0 RmuC family CENP-F_leu_zip PF10473.4 EKE42579.1 - 1.1 9.1 40.1 0.91 9.3 13.5 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 EKE42579.1 - 1.4 9.0 30.5 1.5 8.9 6.8 3.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MSA-2c PF12238.3 EKE42579.1 - 1.9 8.1 18.0 0.62 9.6 3.4 2.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c Vac_Fusion PF02346.11 EKE42579.1 - 2.2 7.7 15.7 0.85 9.0 1.2 3.6 3 1 1 4 4 4 0 Chordopoxvirus fusion protein VWA_2 PF13519.1 EKE42582.1 - 7.8e-15 55.3 0.0 1.1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKE42582.1 - 7e-09 35.6 0.0 3.5e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain CPSF100_C PF13299.1 EKE42582.1 - 0.0024 18.0 0.1 0.0024 18.0 0.1 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal ORC2 PF04084.9 EKE42582.1 - 0.043 12.6 0.1 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 2 VWA_3 PF13768.1 EKE42582.1 - 0.053 13.2 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF3897 PF13036.1 EKE42582.1 - 0.061 12.9 0.6 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3897) Molybdopterin PF00384.17 EKE42582.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Alg14 PF08660.6 EKE42584.1 - 1.6e-52 177.9 0.3 2.7e-52 177.1 0.2 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.11 EKE42584.1 - 1e-27 96.8 0.3 1.8e-27 96.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EKE42584.1 - 8.9e-09 34.9 0.0 2.5e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 1 CLIP PF12032.3 EKE42584.1 - 0.047 13.7 3.3 1.3 9.2 1.5 2.4 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases DUF1510 PF07423.6 EKE42585.1 - 3.1e-05 23.4 2.2 6.3e-05 22.4 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TMEM154 PF15102.1 EKE42585.1 - 0.15 11.7 8.8 0.087 12.5 2.9 3.1 2 1 0 2 2 2 0 TMEM154 protein family E1-E2_ATPase PF00122.15 EKE42586.1 - 2.8e-21 75.6 0.1 2.8e-21 75.6 0.1 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKE42586.1 - 1.7e-14 54.7 0.0 7.2e-14 52.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE42586.1 - 1.5e-12 47.3 0.1 1.8e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EKE42586.1 - 2.5e-12 47.3 0.1 5.7e-12 46.1 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 EKE42586.1 - 0.013 14.3 0.3 0.033 13.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Hydrolase_3 PF08282.7 EKE42586.1 - 0.014 14.9 5.6 0.021 14.4 0.1 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase NifU_N PF01592.11 EKE42588.1 - 6.2e-43 145.7 0.8 1.2e-42 144.8 0.1 1.8 2 0 0 2 2 2 1 NifU-like N terminal domain Fer2_BFD PF04324.10 EKE42588.1 - 1.4e-13 50.6 2.5 3e-13 49.5 0.5 2.6 2 1 1 3 3 3 1 BFD-like [2Fe-2S] binding domain NifU PF01106.12 EKE42588.1 - 4.5e-13 48.7 0.1 1.3e-12 47.2 0.1 1.9 1 0 0 1 1 1 1 NifU-like domain RhoGEF PF00621.15 EKE42589.1 - 1.1e-51 175.2 3.6 2.6e-51 174.0 2.5 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EKE42589.1 - 0.0054 16.9 0.6 0.013 15.6 0.4 1.7 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.12 EKE42590.1 - 9.9e-54 182.1 0.0 1.5e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE42590.1 - 7e-51 172.8 0.0 1.1e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain VSP PF03302.8 EKE42590.1 - 0.0061 15.2 41.7 0.043 12.4 22.5 2.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein Kinase-like PF14531.1 EKE42590.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SP_C-Propep PF08999.5 EKE42590.1 - 0.14 11.6 0.3 0.28 10.6 0.2 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Kdo PF06293.9 EKE42590.1 - 0.17 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3827 PF12877.2 EKE42590.1 - 1.9 6.4 4.3 2.8 5.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MRL1 PF13003.2 EKE42592.1 - 0.26 11.1 5.4 0.077 12.8 1.4 1.8 2 0 0 2 2 2 0 Ribosomal protein L1 RNA_pol_Rpb1_5 PF04998.12 EKE42593.1 - 2.5e-65 220.5 0.5 6.1e-65 219.2 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.13 EKE42593.1 - 3.7e-32 111.2 0.4 3.7e-32 111.2 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EKE42593.1 - 6.6e-21 74.0 3.5 7.6e-21 73.8 0.0 2.9 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 4 Ral PF11058.3 EKE42593.1 - 0.024 13.9 0.3 0.67 9.3 0.0 2.9 2 0 0 2 2 2 0 Antirestriction protein Ral DUF2968 PF11180.3 EKE42594.1 - 0.0034 16.8 2.0 0.0034 16.8 1.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2968) DUF603 PF04645.7 EKE42594.1 - 0.015 15.2 10.6 0.021 14.7 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 MbeD_MobD PF04899.7 EKE42594.1 - 0.025 14.4 0.3 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 MbeD/MobD like LemA PF04011.7 EKE42594.1 - 0.029 13.4 3.0 0.21 10.7 0.1 2.1 1 1 1 2 2 2 0 LemA family DUF3584 PF12128.3 EKE42594.1 - 0.048 10.9 10.5 0.058 10.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin PF02996.12 EKE42594.1 - 0.049 13.2 2.1 0.049 13.2 1.4 3.2 2 1 0 3 3 3 0 Prefoldin subunit HsbA PF12296.3 EKE42594.1 - 0.098 12.5 0.7 0.97 9.3 0.0 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A DUF3007 PF11460.3 EKE42594.1 - 0.11 12.6 2.8 0.092 12.8 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3007) TraB PF01963.12 EKE42594.1 - 0.12 11.8 1.9 0.14 11.5 1.3 1.1 1 0 0 1 1 1 0 TraB family Laminin_I PF06008.9 EKE42594.1 - 0.16 11.2 10.6 0.67 9.2 7.3 2.0 1 1 0 1 1 1 0 Laminin Domain I AAA_11 PF13086.1 EKE42594.1 - 0.18 11.3 7.8 0.21 11.1 5.4 1.0 1 0 0 1 1 1 0 AAA domain Pepsin-I3 PF06394.8 EKE42594.1 - 0.2 11.3 1.4 0.53 9.9 0.9 1.8 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain MCC-bdg_PDZ PF10506.4 EKE42594.1 - 0.21 11.4 4.4 6.2 6.7 0.4 2.4 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3573 PF12097.3 EKE42594.1 - 0.25 9.9 5.1 0.28 9.7 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Prefoldin_3 PF13758.1 EKE42594.1 - 0.3 10.8 10.2 0.27 11.0 3.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit Cob_adeno_trans PF01923.13 EKE42594.1 - 0.31 10.8 1.8 0.5 10.1 1.1 1.6 1 1 0 1 1 1 0 Cobalamin adenosyltransferase CCDC84 PF14968.1 EKE42594.1 - 0.33 10.4 6.4 0.15 11.5 2.9 1.5 1 1 1 2 2 2 0 Coiled coil protein 84 DUF2730 PF10805.3 EKE42594.1 - 0.44 10.2 4.7 0.27 10.9 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) V-SNARE PF05008.10 EKE42594.1 - 0.51 10.5 13.8 0.43 10.7 5.9 3.0 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.6 EKE42594.1 - 0.59 8.7 20.5 8.9 4.8 14.2 2.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF342 PF03961.8 EKE42594.1 - 0.61 8.4 17.5 0.075 11.4 7.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EKE42594.1 - 0.64 7.8 11.9 0.69 7.6 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF310 PF03750.8 EKE42594.1 - 0.71 10.0 7.9 0.19 11.9 3.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF310) Mnd1 PF03962.10 EKE42594.1 - 1 9.0 14.6 0.87 9.2 5.6 2.1 1 1 1 2 2 2 0 Mnd1 family AAA_13 PF13166.1 EKE42594.1 - 1.3 7.4 16.0 1.5 7.1 11.1 1.2 1 0 0 1 1 1 0 AAA domain M_domain PF12938.2 EKE42594.1 - 1.3 8.7 9.5 12 5.6 6.6 2.4 1 1 0 1 1 1 0 M domain of GW182 THP2 PF09432.5 EKE42594.1 - 1.5 8.7 9.5 24 4.7 6.6 2.3 1 1 0 1 1 1 0 Tho complex subunit THP2 Prefoldin_2 PF01920.15 EKE42594.1 - 1.7 8.4 25.2 0.25 11.1 3.5 3.1 1 1 2 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EKE42594.1 - 1.9 8.3 6.3 6.3 6.6 4.4 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.10 EKE42594.1 - 2 7.5 12.0 5.9 5.9 8.3 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF3373 PF11853.3 EKE42594.1 - 2.5 6.5 8.5 1.4 7.3 4.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) DUF4140 PF13600.1 EKE42594.1 - 2.7 8.4 8.3 0.41 11.1 0.4 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EKE42594.1 - 2.8 7.4 16.4 12 5.4 11.4 1.9 1 1 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EKE42594.1 - 3.4 7.7 14.3 0.58 10.2 6.3 2.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EKE42594.1 - 4.3 7.1 10.1 1.3 8.7 4.1 2.2 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 EKE42594.1 - 5.3 7.3 8.7 0.47 10.7 1.5 2.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 EKE42594.1 - 6.2 6.7 22.6 2.8 7.7 5.0 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 EKE42594.1 - 7.1 6.6 19.7 1.3 9.0 1.8 2.9 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DASH_Spc34 PF08657.5 EKE42594.1 - 7.2 6.1 15.2 11 5.5 9.9 1.7 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF155 PF02582.9 EKE42594.1 - 7.5 6.4 9.1 6.4 6.6 2.7 2.4 1 1 1 2 2 2 0 Uncharacterised ACR, YagE family COG1723 ACCA PF03255.9 EKE42594.1 - 8.6 5.9 8.0 2.8 7.4 3.2 1.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Occludin_ELL PF07303.8 EKE42594.1 - 8.9 7.1 14.9 1.5 9.6 4.6 2.1 1 1 1 2 2 2 0 Occludin homology domain SlyX PF04102.7 EKE42594.1 - 9.4 6.6 8.1 2.2 8.7 2.6 2.2 2 1 0 2 2 2 0 SlyX Actin PF00022.14 EKE42595.1 - 7.9e-56 189.1 0.0 1.1e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Actin HMG_box PF00505.14 EKE42596.1 - 1.4e-08 34.8 0.4 1.4e-08 34.8 0.3 3.3 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE42596.1 - 5.8e-06 26.5 2.3 5.8e-06 26.5 1.6 3.5 3 0 0 3 3 3 1 HMG-box domain SR-25 PF10500.4 EKE42596.1 - 0.01 15.3 31.4 0.01 15.3 21.8 2.6 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.10 EKE42596.1 - 1 9.9 6.3 2 8.9 4.4 1.5 1 0 0 1 1 1 0 Chorion family 2 CDC45 PF02724.9 EKE42596.1 - 5.8 4.8 14.5 0.51 8.3 6.8 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF4614 PF15391.1 EKE42596.1 - 6.4 6.4 15.3 2.2 8.0 8.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) CDKN3 PF05706.7 EKE42597.1 - 3.3e-08 33.1 0.1 5.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.15 EKE42597.1 - 3.8e-06 26.5 0.1 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKE42597.1 - 5.7e-06 25.8 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EKE42597.1 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EKE42597.1 - 1.7e-05 25.1 0.0 4.9e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EKE42597.1 - 0.00024 20.5 0.0 0.00049 19.4 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Ski_Sno PF02437.12 EKE42597.1 - 0.11 12.0 1.5 0.49 9.9 0.0 2.7 3 0 0 3 3 3 0 SKI/SNO/DAC family DUF4131 PF13567.1 EKE42597.1 - 5.8 6.2 6.8 0.71 9.2 1.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2009 PF09418.5 EKE42598.1 - 6.6e-110 368.0 6.6 1.2e-101 340.8 1.9 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF2009) Crust_neurohorm PF01147.12 EKE42598.1 - 0.12 11.7 0.1 0.27 10.5 0.1 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family RhoGAP PF00620.22 EKE42599.1 - 2.5e-19 69.4 2.3 3.2e-19 69.0 0.0 2.4 3 1 0 3 3 3 1 RhoGAP domain Cytokin_check_N PF10407.4 EKE42599.1 - 0.03 13.9 2.8 1.3 8.7 0.3 3.1 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus DivIC PF04977.10 EKE42599.1 - 0.046 13.2 1.2 0.21 11.1 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator ACCA PF03255.9 EKE42599.1 - 4 6.9 6.0 14 5.2 0.1 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_DNA_bd PF12329.3 EKE42599.1 - 6.9 6.5 12.0 1.8 8.4 2.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding WH2 PF02205.15 EKE42600.1 - 1.4e-14 53.1 6.3 1.6e-08 33.9 0.5 3.2 3 0 0 3 3 3 3 WH2 motif Sec63 PF02889.11 EKE42600.1 - 0.018 14.2 0.1 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Sec63 Brl domain Thymosin PF01290.15 EKE42600.1 - 0.33 10.5 3.1 1.6 8.3 0.1 2.3 1 1 1 2 2 2 0 Thymosin beta-4 family RRM_1 PF00076.17 EKE42602.1 - 4.4e-09 35.8 0.1 8.3e-09 34.9 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42602.1 - 7.9e-08 32.0 0.1 1.3e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE42602.1 - 1.1e-07 31.6 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YpjP PF14005.1 EKE42604.1 - 0.76 9.5 5.4 1 9.0 2.7 2.0 1 1 0 1 1 1 0 YpjP-like protein DUF2089 PF09862.4 EKE42604.1 - 5.7 6.7 9.5 5.9 6.7 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2089) HEAT_2 PF13646.1 EKE42605.1 - 4e-10 39.8 0.0 6.5e-06 26.3 0.0 4.8 4 2 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EKE42605.1 - 0.00085 19.7 0.2 0.057 13.9 0.0 3.6 2 1 0 2 2 2 1 HEAT-like repeat HEAT PF02985.17 EKE42605.1 - 0.0013 18.5 0.8 0.81 9.9 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat FANCI_S2 PF14676.1 EKE42605.1 - 0.057 13.3 1.1 0.45 10.4 0.1 2.5 1 1 1 2 2 2 0 FANCI solenoid 2 Oxidored_q3 PF00499.15 EKE42606.1 - 0.0021 17.8 2.0 0.0023 17.7 1.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SCAMP PF04144.8 EKE42606.1 - 0.009 15.9 0.8 0.011 15.5 0.6 1.1 1 0 0 1 1 1 1 SCAMP family BPD_transp_2 PF02653.11 EKE42606.1 - 0.011 14.7 2.7 0.013 14.4 1.8 1.0 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component zf-DHHC PF01529.15 EKE42606.1 - 0.088 12.1 4.2 0.091 12.1 2.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2207 PF09972.4 EKE42606.1 - 0.23 9.9 2.7 0.26 9.8 1.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3317 PF11779.3 EKE42606.1 - 0.38 10.2 6.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DUF1980 PF09323.5 EKE42606.1 - 3.3 7.4 6.0 1.1 8.9 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2838 PF10998.3 EKE42609.1 - 6.3e-26 90.4 10.4 6.3e-26 90.4 7.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) SPC12 PF06645.8 EKE42609.1 - 0.79 9.5 7.8 4.4 7.1 0.2 2.8 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ank_4 PF13637.1 EKE42610.1 - 1.7e-17 63.3 5.1 9.4e-08 32.3 0.1 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKE42610.1 - 5.2e-15 55.5 0.6 9.3e-08 32.3 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE42610.1 - 1.3e-13 50.6 2.3 1.6e-05 24.9 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE42610.1 - 9.4e-12 43.9 2.0 0.18 12.1 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Patatin PF01734.17 EKE42610.1 - 6.1e-11 42.6 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Ank PF00023.25 EKE42610.1 - 1.4e-10 40.4 0.1 0.00026 20.6 0.1 5.0 6 0 0 6 6 6 2 Ankyrin repeat UCH PF00443.24 EKE42611.1 - 1.7e-44 151.9 11.3 1.7e-44 151.9 7.8 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE42611.1 - 6e-17 62.0 10.7 4.3e-15 55.9 3.7 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Nitroreductase PF00881.19 EKE42612.1 - 1e-27 96.9 0.0 1.3e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family OB_NTP_bind PF07717.11 EKE42612.1 - 0.044 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold NadA PF02445.11 EKE42612.1 - 0.056 12.2 0.1 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein TLD PF07534.11 EKE42613.1 - 1.4e-05 25.1 0.7 3.7e-05 23.7 0.4 1.7 1 1 1 2 2 2 2 TLD Hexapep PF00132.19 EKE42614.1 - 7.7e-14 50.4 12.4 1.2e-09 37.2 2.6 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKE42614.1 - 0.00048 19.6 3.0 0.00048 19.6 2.1 2.9 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.9 EKE42614.1 - 0.0017 18.5 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal DAGK_acc PF00609.14 EKE42615.1 - 3.5e-39 134.5 0.0 5.3e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EKE42615.1 - 8.6e-20 70.4 0.0 1.3e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EKE42615.1 - 1.7e-12 46.8 47.5 4e-05 23.2 5.1 3.6 3 1 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_kinase PF01513.16 EKE42615.1 - 0.13 10.9 0.7 0.47 9.1 0.5 1.9 1 1 0 1 1 1 0 ATP-NAD kinase MFS_1 PF07690.11 EKE42616.1 - 1.2e-17 63.6 36.0 1.2e-17 63.6 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKE42616.1 - 4.4e-14 51.7 28.8 6e-14 51.2 20.0 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein DUF1129 PF06570.6 EKE42616.1 - 4.2 6.6 14.3 0.23 10.7 3.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) DUF4064 PF13273.1 EKE42616.1 - 7.6 6.7 28.0 1.1 9.4 0.8 5.1 4 2 2 6 6 6 0 Protein of unknown function (DUF4064) Ras PF00071.17 EKE42617.1 - 6.5e-22 77.6 0.5 7.7e-22 77.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42617.1 - 6e-11 42.8 0.3 1.1e-10 42.0 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE42617.1 - 0.00079 18.7 0.3 0.00097 18.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKE42617.1 - 0.0013 18.1 0.1 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EKE42617.1 - 0.0078 15.8 0.2 0.024 14.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKE42617.1 - 0.019 14.4 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EKE42617.1 - 0.02 15.0 0.1 1.4 9.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF4061 PF13270.1 EKE42617.1 - 0.044 13.8 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) AAA_16 PF13191.1 EKE42617.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TatD_DNase PF01026.16 EKE42618.1 - 6.1e-29 100.9 0.2 2.6e-28 98.9 0.0 1.8 1 1 1 2 2 2 1 TatD related DNase eIF-5_eIF-2B PF01873.12 EKE42619.1 - 6.8e-33 112.9 2.0 1e-32 112.4 1.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Elf1 PF05129.8 EKE42619.1 - 0.023 14.4 3.4 0.023 14.4 2.4 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like KSR1-SAM PF13543.1 EKE42619.1 - 0.081 12.7 2.7 4.4 7.1 0.0 3.0 2 1 1 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 Exo_endo_phos PF03372.18 EKE42620.1 - 1.1e-16 61.5 0.0 1.6e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EKE42620.1 - 0.00016 21.3 0.1 0.0004 20.0 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain DAGK_acc PF00609.14 EKE42621.1 - 6.6e-10 39.3 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.17 EKE42621.1 - 1.6e-09 37.3 50.9 0.00028 20.5 5.5 3.4 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EKE42621.1 - 0.003 17.5 3.3 0.003 17.5 2.3 4.0 3 1 0 3 3 3 1 C1-like domain DUF3990 PF13151.1 EKE42621.1 - 0.066 12.5 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) RhoGEF PF00621.15 EKE42622.1 - 2e-44 151.6 2.9 6.2e-44 150.0 1.3 2.3 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EKE42622.1 - 5.4e-14 51.8 18.2 1.5e-13 50.4 12.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EKE42622.1 - 6.9e-09 35.8 0.0 6.9e-09 35.8 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EKE42622.1 - 0.011 15.9 2.9 0.66 10.2 0.0 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain PH_8 PF15409.1 EKE42622.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain FAM176 PF14851.1 EKE42622.1 - 5.5 6.6 7.1 12 5.6 4.9 1.6 1 0 0 1 1 1 0 FAM176 family C2 PF00168.25 EKE42623.1 - 1e-19 70.1 0.2 3e-19 68.6 0.3 1.7 2 0 0 2 2 2 1 C2 domain RRM_1 PF00076.17 EKE42624.1 - 2.7e-28 97.4 3.8 1.7e-15 56.4 0.2 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EKE42624.1 - 5e-24 83.0 30.4 1.3e-06 27.9 2.3 4.5 4 0 0 4 4 4 4 Zinc knuckle RRM_6 PF14259.1 EKE42624.1 - 3.8e-18 65.2 0.1 4.9e-09 36.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42624.1 - 1.6e-13 50.2 0.5 5e-07 29.4 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.1 EKE42624.1 - 8.5e-13 47.5 17.9 0.0056 16.1 0.1 4.3 2 1 2 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EKE42624.1 - 1.9e-11 43.4 26.3 0.0036 16.9 0.6 5.3 4 0 0 4 4 4 4 Zinc knuckle RNA_bind PF08675.6 EKE42624.1 - 8.5e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain Nup35_RRM_2 PF14605.1 EKE42624.1 - 4.3e-05 23.2 0.2 0.0003 20.4 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EKE42624.1 - 0.0003 20.4 2.0 0.029 14.1 0.0 2.7 2 0 0 2 2 2 1 Limkain b1 SANTA PF09133.5 EKE42624.1 - 0.053 13.4 0.1 7.4 6.6 0.0 2.6 2 0 0 2 2 2 0 SANTA (SANT Associated) zf-CCHC_6 PF15288.1 EKE42624.1 - 0.061 13.0 28.1 0.094 12.4 1.2 5.2 2 1 3 5 5 5 0 Zinc knuckle AFP PF02420.10 EKE42624.1 - 1.3 9.3 4.3 1.6e+02 2.9 0.0 4.6 4 0 0 4 4 4 0 Insect antifreeze protein repeat zf-CCHC_3 PF13917.1 EKE42624.1 - 2.2 8.0 18.4 3.3 7.5 0.2 4.4 1 1 3 4 4 4 0 Zinc knuckle Toxin_13 PF07822.6 EKE42625.1 - 4.3 7.3 7.6 3.8 7.4 3.4 2.1 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein Rtt102p PF09510.5 EKE42626.1 - 0.093 12.7 0.3 0.11 12.5 0.2 1.1 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Skp1_POZ PF03931.10 EKE42627.1 - 6.9e-16 58.1 0.0 1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 EKE42627.1 - 0.00048 20.0 0.0 0.00077 19.4 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain zf-RING_2 PF13639.1 EKE42628.1 - 2.5e-07 30.4 8.0 2.5e-07 30.4 5.5 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EKE42628.1 - 0.00058 19.4 9.2 0.00058 19.4 6.4 2.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKE42628.1 - 0.0046 16.6 1.8 0.0046 16.6 1.2 3.1 3 1 0 3 3 3 1 RING-type zinc-finger PHD PF00628.24 EKE42628.1 - 0.01 15.5 5.8 0.01 15.5 4.1 2.6 2 0 0 2 2 2 1 PHD-finger zf-B_box PF00643.19 EKE42628.1 - 0.016 15.0 15.0 0.016 15.0 10.4 3.2 3 1 0 3 3 3 0 B-box zinc finger zf-C3HC4_2 PF13923.1 EKE42628.1 - 0.018 15.0 7.2 0.018 15.0 5.0 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE42628.1 - 0.046 13.3 24.8 0.075 12.7 3.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 EKE42628.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.9 4 1 1 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger MS_channel PF00924.13 EKE42629.1 - 3.9e-11 42.6 6.1 3.9e-11 42.6 4.2 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel HTH_9 PF08221.6 EKE42630.1 - 7.8e-09 35.2 1.9 0.0036 17.1 0.1 3.6 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 EKE42630.1 - 0.00013 21.6 1.3 0.012 15.1 0.3 3.3 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 TLD PF07534.11 EKE42631.1 - 0.00076 19.4 1.3 0.0014 18.5 0.9 1.5 1 0 0 1 1 1 1 TLD eRF1_2 PF03464.10 EKE42632.1 - 3.2e-41 140.7 0.0 6e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EKE42632.1 - 1.9e-35 121.5 1.3 5.7e-35 120.0 0.1 2.2 2 1 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 EKE42632.1 - 1.6e-24 85.9 0.0 2.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EKE42632.1 - 0.031 13.7 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Zip PF02535.17 EKE42633.1 - 1.1e-38 132.9 17.0 2.2e-38 132.0 11.8 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter WD40 PF00400.27 EKE42634.1 - 2e-19 68.6 13.3 3.3e-06 26.7 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat MBOAT PF03062.14 EKE42636.1 - 2.6e-25 89.2 24.9 2.6e-25 89.2 17.2 2.9 1 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family BCAS2 PF05700.6 EKE42637.1 - 0.0032 16.9 5.2 0.0038 16.7 3.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4337 PF14235.1 EKE42637.1 - 0.046 13.5 0.5 0.049 13.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Tetraspannin PF00335.15 EKE42638.1 - 0.0065 15.7 16.6 0.01 15.0 11.5 1.4 1 0 0 1 1 1 1 Tetraspanin family AmiS_UreI PF02293.10 EKE42638.1 - 0.012 15.2 2.3 0.02 14.5 1.6 1.3 1 0 0 1 1 1 0 AmiS/UreI family transporter DUF4231 PF14015.1 EKE42638.1 - 0.073 13.0 2.0 0.22 11.5 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4133 PF13571.1 EKE42638.1 - 0.24 11.6 2.3 0.27 11.4 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) DUF3366 PF11846.3 EKE42638.1 - 0.49 10.2 2.4 0.99 9.2 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3366) Claudin_2 PF13903.1 EKE42638.1 - 1.2 8.8 11.2 0.58 9.8 4.7 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction NfeD PF01957.13 EKE42638.1 - 2.4 8.2 8.8 0.045 13.8 1.4 1.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding SK_channel PF03530.9 EKE42638.1 - 3.2 7.6 8.7 3.7 7.3 4.7 1.8 1 1 1 2 2 2 0 Calcium-activated SK potassium channel G3P_acyltransf PF02660.10 EKE42638.1 - 3.9 6.9 10.8 0.71 9.4 4.6 1.7 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Pox_A14 PF05767.7 EKE42638.1 - 5.8 6.9 14.6 0.2 11.6 1.7 3.0 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 ABC2_membrane PF01061.19 EKE42639.1 - 2.9e-15 56.0 22.1 2.9e-15 56.0 15.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter Inhibitor_G39P PF11417.3 EKE42639.1 - 0.099 12.6 0.9 3.3 7.7 0.0 3.1 2 1 0 2 2 2 0 Loader and inhibitor of phage G40P His_Phos_2 PF00328.17 EKE42640.1 - 3.5e-16 59.4 0.2 2.7e-10 40.0 0.0 2.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EKE42640.1 - 0.00058 19.9 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S5_C PF03719.10 EKE42640.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain HTH_7 PF02796.10 EKE42640.1 - 0.056 13.3 0.1 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SRP40_C PF05022.7 EKE42642.1 - 6.3e-08 32.9 2.3 6.3e-08 32.9 1.6 4.3 3 2 2 5 5 5 1 SRP40, C-terminal domain LisH PF08513.6 EKE42642.1 - 1.5e-06 27.7 0.1 3.4e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 LisH TLD PF07534.11 EKE42643.1 - 0.00053 20.0 1.5 0.00053 20.0 1.0 2.6 2 1 0 2 2 2 1 TLD HiaBD2 PF15403.1 EKE42643.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF1053 PF06327.9 EKE42643.1 - 0.059 13.7 7.4 0.048 14.0 3.9 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) 60KD_IMP PF02096.15 EKE42643.1 - 7.3 6.1 8.5 13 5.3 5.9 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein RICTOR_V PF14668.1 EKE42644.1 - 0.01 15.7 0.1 1.4 8.8 0.0 2.8 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 PTS_2-RNA PF01885.11 EKE42645.1 - 4.4e-58 195.6 1.2 5.6e-58 195.3 0.9 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Oligomerisation PF02410.10 EKE42645.1 - 0.083 12.9 0.9 6.7 6.8 0.6 2.2 1 1 0 1 1 1 0 Oligomerisation domain Cpn60_TCP1 PF00118.19 EKE42647.1 - 2.7e-139 464.9 14.7 3.1e-139 464.7 10.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DGC PF08859.6 EKE42647.1 - 0.16 11.8 3.2 0.69 9.7 0.9 2.9 2 1 1 3 3 3 0 DGC domain Tfb2 PF03849.9 EKE42648.1 - 0.13 10.8 2.8 0.15 10.7 2.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 DUF1003 PF06210.6 EKE42648.1 - 2.5 8.0 8.2 7.3 6.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Lipoxygenase PF00305.14 EKE42648.1 - 2.8 5.8 7.8 0.78 7.6 3.4 1.4 1 1 0 1 1 1 0 Lipoxygenase DUF720 PF05302.6 EKE42648.1 - 6 6.6 7.1 0.66 9.7 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF720) Pkinase PF00069.20 EKE42649.1 - 9e-34 116.7 0.0 1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42649.1 - 4.7e-13 48.8 0.0 4.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE42649.1 - 1.2e-08 34.9 0.1 2e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EKE42649.1 - 0.00091 18.6 0.4 0.0023 17.3 0.3 1.7 1 1 0 1 1 1 1 RIO1 family L_protein_N PF15518.1 EKE42649.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 L protein N-terminus Kdo PF06293.9 EKE42649.1 - 0.12 11.4 0.1 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.26 EKE42650.1 - 3.6e-30 103.7 3.6 2.5e-15 56.2 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE42650.1 - 1.1e-24 86.3 5.3 6.1e-17 61.4 0.7 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EKE42650.1 - 0.017 14.8 0.8 0.21 11.3 0.1 2.8 1 1 1 2 2 2 0 Rap1 Myb domain Nop16 PF09420.5 EKE42651.1 - 4.8e-13 49.5 0.5 4.8e-13 49.5 0.4 2.8 2 1 0 2 2 1 1 Ribosome biogenesis protein Nop16 CENP-T PF15511.1 EKE42651.1 - 0.014 14.6 14.4 0.015 14.5 10.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RNA_polI_A34 PF08208.6 EKE42651.1 - 0.048 13.3 21.3 0.06 13.0 14.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.3 EKE42651.1 - 0.11 11.0 17.2 0.15 10.6 12.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SprA-related PF12118.3 EKE42651.1 - 0.65 9.2 20.1 0.71 9.1 13.9 1.2 1 0 0 1 1 1 0 SprA-related family Nop14 PF04147.7 EKE42651.1 - 1.1 7.1 29.9 1.2 6.9 20.8 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.7 EKE42651.1 - 1.6 8.5 26.3 2 8.2 18.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EKE42651.1 - 1.7 7.9 28.9 2.5 7.4 20.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EKE42651.1 - 2 6.0 18.6 1.8 6.2 12.9 1.2 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 EKE42651.1 - 2.6 5.9 25.3 3.3 5.6 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 EKE42651.1 - 3.4 5.2 14.0 3.4 5.2 9.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.1 EKE42651.1 - 4.2 7.3 23.4 8.2 6.4 16.2 1.6 1 0 0 1 1 1 0 YqfQ-like protein Zip PF02535.17 EKE42651.1 - 4.6 6.1 7.5 5.2 5.9 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CT47 PF15623.1 EKE42651.1 - 7.5 6.2 26.4 10 5.7 18.3 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF947 PF06102.7 EKE42652.1 - 6.4e-25 87.8 25.3 7.9e-25 87.6 17.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF947) VCBS PF13517.1 EKE42653.1 - 1.1e-08 35.2 1.8 0.37 11.1 0.3 4.1 3 1 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EKE42653.1 - 2.6e-05 23.7 12.5 0.024 14.3 0.0 4.1 4 0 0 4 4 4 2 FG-GAP repeat PQQ_2 PF13360.1 EKE42653.1 - 0.00019 20.9 0.0 2.8 7.3 0.0 4.5 3 1 1 4 4 4 2 PQQ-like domain LRR_adjacent PF08191.6 EKE42654.1 - 0.095 12.4 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 LRR adjacent Gelsolin PF00626.17 EKE42655.1 - 1.7e-19 69.2 0.8 7.4e-09 35.1 0.0 4.4 4 0 0 4 4 4 3 Gelsolin repeat VHP PF02209.14 EKE42655.1 - 3.7e-12 45.7 0.8 1.3e-11 43.9 0.6 2.1 1 0 0 1 1 1 1 Villin headpiece domain ATP-synt_F PF01990.12 EKE42656.1 - 3.7e-27 94.5 0.1 4.5e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit eIF-5_eIF-2B PF01873.12 EKE42656.1 - 0.037 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 DXP_synthase_N PF13292.1 EKE42656.1 - 0.095 11.6 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF4064 PF13273.1 EKE42657.1 - 0.0016 18.5 1.2 0.004 17.2 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Glyco_hydro_42M PF08532.5 EKE42657.1 - 0.057 12.5 0.1 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Ank_2 PF12796.2 EKE42658.1 - 1.6e-20 73.1 1.8 5.9e-15 55.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKE42658.1 - 1.6e-17 63.4 0.4 5.5e-10 39.4 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKE42658.1 - 1.1e-14 54.1 0.7 1.5e-08 34.6 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EKE42658.1 - 1.5e-13 49.8 0.5 0.00039 20.0 0.1 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EKE42658.1 - 5.9e-10 38.4 0.4 0.00033 20.5 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat RVP PF00077.15 EKE42658.1 - 0.01 15.7 0.1 0.027 14.4 0.1 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF2492 PF10678.4 EKE42658.1 - 0.022 14.8 0.2 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) DUF1125 PF06563.6 EKE42658.1 - 0.064 12.9 0.5 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1125) TLD PF07534.11 EKE42659.1 - 1.5e-05 24.9 0.2 3.4e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 TLD ICEA PF05315.6 EKE42659.1 - 0.0068 15.7 0.3 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 ICEA Protein SapB_2 PF03489.12 EKE42660.1 - 8.3e-08 32.1 0.3 1.6e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EKE42660.1 - 0.001 18.8 0.6 0.001 18.8 0.4 2.4 2 1 0 2 2 2 1 Saposin-like type B, region 1 GPW_gp25 PF04965.9 EKE42660.1 - 0.07 12.6 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Gene 25-like lysozyme DUF4365 PF14280.1 EKE42660.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) RhoGEF PF00621.15 EKE42662.1 - 3.5e-23 82.4 1.3 3.5e-23 82.4 0.9 2.0 2 0 0 2 2 2 1 RhoGEF domain MRP-L28 PF09812.4 EKE42662.1 - 0.27 11.0 13.2 0.68 9.7 9.2 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 WD40 PF00400.27 EKE42663.1 - 1.9e-08 33.8 2.2 0.0004 20.1 0.2 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKE42663.1 - 0.0016 18.2 0.0 0.0076 16.0 0.0 2.2 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 EKE42664.1 - 5.2e-15 55.4 0.0 0.00052 20.2 0.0 5.8 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EKE42664.1 - 6.7e-15 53.7 0.8 0.023 14.7 0.0 7.5 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 EKE42664.1 - 3.8e-09 36.7 0.2 0.081 13.4 0.0 6.1 6 1 2 8 8 8 2 HEAT-like repeat B56 PF01603.15 EKE42664.1 - 4.9e-06 25.3 1.5 0.05 12.2 0.0 3.7 2 1 1 3 3 3 3 Protein phosphatase 2A regulatory B subunit (B56 family) Cnd1 PF12717.2 EKE42664.1 - 7.7e-06 25.8 12.6 0.065 13.0 0.1 5.6 3 3 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EKE42664.1 - 1.1e-05 25.7 5.4 0.0015 18.9 0.1 4.8 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EKE42664.1 - 0.0035 16.7 2.9 0.029 13.7 0.1 3.2 3 1 1 4 4 4 1 CLASP N terminal V-ATPase_H_C PF11698.3 EKE42664.1 - 0.051 13.5 2.8 0.52 10.2 0.0 3.4 4 0 0 4 4 4 0 V-ATPase subunit H Cohesin_HEAT PF12765.2 EKE42664.1 - 0.056 13.4 0.2 7.9 6.5 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 EKE42664.1 - 0.17 11.7 5.9 4.7 7.1 0.0 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cullin PF00888.17 EKE42665.1 - 1.3e-23 83.4 26.6 1.3e-23 83.4 18.5 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EKE42665.1 - 4.2e-19 68.1 6.1 4.2e-19 68.1 4.2 4.2 4 0 0 4 4 4 1 Cullin protein neddylation domain DUF4261 PF14080.1 EKE42665.1 - 0.0038 16.9 0.8 1.6 8.5 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4261) SieB PF14163.1 EKE42665.1 - 0.014 15.0 6.8 0.3 10.6 0.8 3.7 3 1 0 3 3 3 0 Superinfection exclusion protein B Exo_endo_phos PF03372.18 EKE42666.1 - 1.9e-06 27.9 0.0 3.1e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PsbI PF02532.9 EKE42666.1 - 8.3 6.1 6.6 17 5.1 4.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Beach PF02138.13 EKE42667.1 - 8.2e-97 323.8 8.0 8.2e-97 323.8 5.5 2.9 3 0 0 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.1 EKE42667.1 - 1.1e-11 44.4 0.7 5.7e-11 42.2 0.5 2.4 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EKE42667.1 - 0.0047 16.7 0.0 4.2 7.4 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EKE42667.1 - 0.48 10.6 0.0 1.3 9.2 0.0 1.7 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Orbi_VP4 PF05059.7 EKE42668.1 - 0.17 9.6 0.4 0.2 9.3 0.3 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein Leader_Erm PF08253.6 EKE42668.1 - 0.19 11.1 2.0 0.45 10.0 1.4 1.6 1 0 0 1 1 1 0 Erm Leader peptide DUF4051 PF13260.1 EKE42668.1 - 0.5 9.7 2.8 1 8.7 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Ribophorin_II PF05817.9 EKE42668.1 - 0.67 8.0 15.4 0.76 7.9 10.6 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II FA_desaturase PF00487.19 EKE42668.1 - 0.69 9.3 9.0 0.88 8.9 6.2 1.0 1 0 0 1 1 1 0 Fatty acid desaturase Ras PF00071.17 EKE42669.1 - 7e-49 165.3 0.3 9.9e-49 164.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42669.1 - 2.2e-20 73.2 0.0 4.1e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42669.1 - 2.3e-12 46.5 1.7 3.3e-11 42.7 0.1 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 EKE42669.1 - 8e-06 25.1 0.4 1.8e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE42669.1 - 1e-05 24.8 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE42669.1 - 3.5e-05 23.3 0.2 0.00027 20.4 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKE42669.1 - 0.00019 21.3 0.0 0.00094 19.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE42669.1 - 0.0048 16.1 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Lact_bio_phlase PF09508.5 EKE42669.1 - 0.044 11.4 0.3 0.076 10.6 0.2 1.3 1 1 0 1 1 1 0 Lacto-N-biose phosphorylase YqcI_YcgG PF08892.6 EKE42669.1 - 0.052 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 YqcI/YcgG family DUF1681 PF07933.9 EKE42670.1 - 5e-28 97.6 0.5 1.6e-27 96.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) CFIA_Pcf11 PF11526.3 EKE42670.1 - 3 8.0 9.7 0.1 12.7 0.7 2.4 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Pmp3 PF01679.12 EKE42672.1 - 1.6e-18 66.1 14.7 1.8e-18 65.9 10.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3975 PF13126.1 EKE42672.1 - 0.038 14.1 6.4 0.041 14.0 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) Sdh_cyt PF01127.17 EKE42672.1 - 0.19 11.5 4.1 0.22 11.3 2.9 1.0 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF872 PF05915.7 EKE42672.1 - 2.2 8.1 4.1 2.8 7.8 2.8 1.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) MpPF26 PF07666.6 EKE42672.1 - 2.5 8.0 11.7 3.2 7.6 3.8 2.0 1 1 1 2 2 2 0 M penetrans paralogue family 26 FH2 PF02181.18 EKE42673.1 - 5.6e-25 87.9 0.2 5.6e-25 87.9 0.1 4.2 4 0 0 4 4 4 3 Formin Homology 2 Domain LRR_4 PF12799.2 EKE42674.1 - 2.7e-49 164.0 83.5 2.8e-08 33.1 3.5 11.8 2 2 7 13 13 13 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE42674.1 - 2.9e-39 132.6 97.4 3.7e-08 33.0 1.0 8.8 3 1 9 12 12 12 11 Leucine rich repeat LRR_1 PF00560.28 EKE42674.1 - 1.3e-27 91.5 71.0 0.0025 17.6 0.1 18.8 20 0 0 20 20 20 8 Leucine Rich Repeat LRR_7 PF13504.1 EKE42674.1 - 2.1e-15 54.1 51.2 0.015 15.3 0.1 15.6 16 0 0 16 16 16 6 Leucine rich repeat LRR_9 PF14580.1 EKE42674.1 - 8.2e-06 25.4 22.4 0.018 14.5 1.3 4.9 1 1 4 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.1 EKE42674.1 - 8.5e-05 22.2 65.2 0.15 12.1 0.0 14.4 15 3 2 17 17 17 6 Leucine Rich repeat Peptidase_M22 PF00814.20 EKE42675.1 - 4.5e-86 288.6 0.1 5.3e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 EKE42675.1 - 0.075 12.1 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Pex16 PF08610.5 EKE42676.1 - 0.0014 17.6 0.1 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Chorein_N PF12624.2 EKE42677.1 - 8.7e-35 118.8 0.9 5.6e-34 116.2 0.1 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter TAF4 PF05236.9 EKE42678.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Sec7 PF01369.15 EKE42679.1 - 3.4e-36 124.7 0.0 1.6e-35 122.4 0.0 2.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EKE42679.1 - 1.2e-12 47.6 7.6 1.2e-12 47.6 5.3 5.3 8 0 0 8 8 8 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EKE42679.1 - 1.9e-10 40.0 4.1 1.2e-09 37.5 0.1 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) LRR_5 PF13306.1 EKE42680.1 - 3.5e-95 314.5 38.9 4.6e-33 113.6 6.7 3.6 2 1 3 5 5 5 4 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42680.1 - 4.4e-21 74.3 5.9 4.8e-07 29.4 0.3 5.1 2 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EKE42680.1 - 0.014 15.0 3.7 4 7.1 0.2 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Crystall PF00030.14 EKE42681.1 - 0.23 11.3 4.1 19 5.2 0.1 3.3 3 0 0 3 3 3 0 Beta/Gamma crystallin PFU PF09070.6 EKE42682.1 - 1e-11 44.8 0.4 4e-11 42.9 0.0 2.0 2 1 1 3 3 3 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EKE42682.1 - 1.7e-06 27.0 1.6 2.5e-06 26.4 1.1 1.4 1 0 0 1 1 1 1 PUL domain MTH865 PF07747.6 EKE42682.1 - 0.029 13.9 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 MTH865-like family CAT_RBD PF03123.10 EKE42683.1 - 0.15 11.7 3.8 2.7 7.7 0.3 2.9 2 0 0 2 2 2 0 CAT RNA binding domain DTW PF03942.10 EKE42686.1 - 5.8e-21 74.6 0.0 7.6e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 DTW domain DUF367 PF04034.8 EKE42686.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF367) SDA1 PF05285.7 EKE42687.1 - 7e-37 127.4 38.3 7e-37 127.4 26.6 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EKE42687.1 - 0.00065 19.9 0.7 0.0016 18.6 0.0 2.1 2 0 0 2 2 2 1 NUC130/3NT domain HEAT_2 PF13646.1 EKE42687.1 - 0.0066 16.6 0.2 0.15 12.4 0.1 2.8 3 0 0 3 3 3 1 HEAT repeats DUF4381 PF14316.1 EKE42688.1 - 0.095 12.8 0.0 1.8 8.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Gelsolin PF00626.17 EKE42689.1 - 3.2e-30 103.6 6.2 1.4e-09 37.4 0.0 7.3 6 0 0 6 6 6 6 Gelsolin repeat TrkH PF02386.11 EKE42690.1 - 1e-59 201.9 25.1 8.6e-58 195.5 11.3 2.7 2 1 0 2 2 2 2 Cation transport protein Peptidase_M56 PF05569.6 EKE42690.1 - 0.029 13.3 1.7 0.074 12.0 0.4 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF4538 PF15061.1 EKE42690.1 - 0.097 11.9 2.3 0.57 9.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Pkinase PF00069.20 EKE42691.1 - 3.4e-57 193.5 2.1 1.6e-56 191.3 1.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42691.1 - 1.3e-39 135.8 0.8 3.7e-39 134.3 0.5 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKE42691.1 - 4.5e-12 45.8 0.5 1.3e-11 44.4 0.3 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EKE42691.1 - 6.2e-05 22.1 0.0 0.00013 20.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKE42691.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.17 EKE42692.1 - 2.3e-08 33.6 0.8 4.6e-08 32.6 0.6 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42692.1 - 0.00037 20.9 0.3 0.00093 19.6 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EKE42692.1 - 0.001 18.9 0.0 0.003 17.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EKE42692.1 - 0.013 15.0 0.3 0.12 11.8 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EKE42692.1 - 0.061 12.5 0.3 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_21 PF13304.1 EKE42692.1 - 0.1 12.5 1.7 0.19 11.6 1.2 1.6 1 1 0 1 1 1 0 AAA domain Diphthamide_syn PF01866.12 EKE42693.1 - 1.2e-74 251.3 0.0 1.5e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Kelch_1 PF01344.20 EKE42693.1 - 0.08 12.4 0.3 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Kelch motif TetR_C_4 PF08359.6 EKE42693.1 - 0.092 12.6 0.1 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region Prefoldin_2 PF01920.15 EKE42694.1 - 6.7e-11 41.8 8.4 7.8e-11 41.6 5.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit V_ATPase_I PF01496.14 EKE42694.1 - 0.003 15.4 5.5 0.0031 15.4 3.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Fungal_trans_2 PF11951.3 EKE42694.1 - 0.012 14.2 0.2 0.013 14.1 0.1 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain Occludin_ELL PF07303.8 EKE42694.1 - 0.024 15.3 5.4 0.027 15.1 3.0 1.6 1 1 1 2 2 2 0 Occludin homology domain CENP-Q PF13094.1 EKE42694.1 - 0.045 13.7 2.7 0.062 13.3 1.9 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 EKE42694.1 - 0.077 12.7 8.2 0.63 9.7 2.8 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DASH_Dad3 PF08656.5 EKE42694.1 - 0.097 12.3 3.2 0.51 10.0 0.3 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad3 Prefoldin PF02996.12 EKE42694.1 - 0.1 12.2 3.4 0.29 10.7 1.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit XhlA PF10779.4 EKE42694.1 - 0.31 10.9 8.8 2.6 8.0 3.3 2.2 2 0 0 2 2 2 0 Haemolysin XhlA IncA PF04156.9 EKE42694.1 - 0.4 10.2 3.9 0.46 10.0 2.7 1.1 1 0 0 1 1 1 0 IncA protein Med4 PF10018.4 EKE42694.1 - 0.58 9.5 5.0 1.3 8.3 1.4 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Fzo_mitofusin PF04799.8 EKE42694.1 - 0.79 9.0 4.3 1.2 8.4 0.9 2.0 1 1 1 2 2 2 0 fzo-like conserved region STAT_alpha PF01017.15 EKE42694.1 - 0.82 9.3 7.5 1 9.0 5.2 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Ax_dynein_light PF10211.4 EKE42694.1 - 2.7 7.7 7.6 1.9 8.3 2.4 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DivIC PF04977.10 EKE42694.1 - 2.7 7.5 5.7 3.3 7.2 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 EKE42694.1 - 7.6 6.6 8.1 9.7 6.3 1.5 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CH PF00307.26 EKE42695.1 - 6.4e-21 74.4 8.9 3.4e-10 39.9 0.0 3.8 4 1 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKE42695.1 - 5.8e-07 29.0 0.1 0.069 12.7 0.0 3.4 3 0 0 3 3 3 2 CAMSAP CH domain 2-ph_phosp PF04029.9 EKE42696.1 - 1.1e-38 132.5 0.0 2e-38 131.6 0.0 1.4 1 1 0 1 1 1 1 2-phosphosulpholactate phosphatase RhoGAP PF00620.22 EKE42697.1 - 1.4e-23 83.1 0.5 1.4e-23 83.1 0.3 2.1 2 1 0 2 2 2 1 RhoGAP domain Muted PF14942.1 EKE42697.1 - 0.00058 19.7 1.3 0.00058 19.7 0.9 1.7 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein NTF2 PF02136.15 EKE42697.1 - 0.086 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SPATIAL PF15256.1 EKE42697.1 - 0.33 10.9 7.3 0.5 10.3 5.1 1.4 1 1 0 1 1 1 0 SPATIAL SAC3_GANP PF03399.11 EKE42698.1 - 8.5e-27 94.0 4.8 8.5e-27 94.0 3.3 1.6 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EKE42698.1 - 0.0002 21.1 0.1 0.00073 19.3 0.1 1.9 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RhoGEF PF00621.15 EKE42699.1 - 4.4e-32 111.4 1.8 4.4e-32 111.4 1.2 2.4 2 1 0 2 2 2 1 RhoGEF domain Peptidase_S9 PF00326.16 EKE42701.1 - 1.1e-18 67.2 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EKE42701.1 - 0.0065 15.7 0.0 0.16 11.2 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKE42701.1 - 0.013 15.2 0.0 0.038 13.7 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EKE42702.1 - 7.8e-08 31.7 0.7 2.2e-06 27.0 0.5 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42702.1 - 1.5e-06 27.5 0.0 7.7e-06 25.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DAGK_acc PF00609.14 EKE42703.1 - 3.3e-40 137.8 0.0 5.1e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EKE42703.1 - 2.2e-20 72.3 0.0 3.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EKE42703.1 - 7.8e-17 60.7 36.8 8.1e-07 28.6 4.0 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EKE42703.1 - 2.1e-05 24.4 31.8 0.017 15.1 3.5 3.7 3 0 0 3 3 3 3 C1-like domain Ras PF00071.17 EKE42704.1 - 4.3e-08 32.7 0.9 5.8e-07 29.0 0.7 2.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKE42704.1 - 2.1e-07 31.4 4.7 7e-07 29.7 0.2 3.4 3 1 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 EKE42704.1 - 2.3e-06 27.5 0.1 8.7e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKE42704.1 - 0.00082 18.6 1.9 0.00086 18.6 0.2 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EKE42704.1 - 0.0022 17.2 0.0 0.0064 15.7 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EKE42704.1 - 0.054 12.6 0.1 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CDP-OH_P_transf PF01066.16 EKE42708.1 - 1.7e-19 69.9 4.0 1.7e-19 69.9 2.8 3.2 2 2 1 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF900 PF05990.7 EKE42709.1 - 4e-26 91.7 0.0 7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EKE42709.1 - 0.24 11.1 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2963 PF11178.3 EKE42709.1 - 0.53 9.7 5.7 1.3 8.5 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) DUF3488 PF11992.3 EKE42709.1 - 2.5 6.6 7.5 3.9 6.0 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Ras PF00071.17 EKE42710.1 - 2.9e-52 176.3 0.2 3.4e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKE42710.1 - 1.7e-20 72.9 0.1 2.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKE42710.1 - 7.9e-18 65.0 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EKE42710.1 - 9.3e-08 31.7 0.0 8.8e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKE42710.1 - 3.6e-05 23.0 0.1 4.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKE42710.1 - 0.00011 21.4 0.1 0.0004 19.6 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKE42710.1 - 0.00062 19.7 0.1 0.0013 18.7 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EKE42710.1 - 0.00075 18.9 0.1 0.009 15.5 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EKE42710.1 - 0.0096 16.0 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EKE42710.1 - 0.012 14.9 0.0 0.032 13.5 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 EKE42710.1 - 0.021 13.8 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_15 PF13175.1 EKE42710.1 - 0.057 12.4 2.6 0.08 11.9 1.8 1.3 1 1 0 1 1 1 0 AAA ATPase domain SH3_9 PF14604.1 EKE42711.1 - 1.8e-33 113.8 1.3 4.2e-08 32.6 0.1 6.0 6 0 0 6 6 6 5 Variant SH3 domain SH3_2 PF07653.12 EKE42711.1 - 3.2e-31 106.5 0.6 2.4e-06 26.9 0.0 6.2 6 0 0 6 6 6 5 Variant SH3 domain SH3_1 PF00018.23 EKE42711.1 - 1.3e-28 98.1 2.4 7.9e-05 21.9 0.0 6.2 6 0 0 6 6 6 5 SH3 domain Ala_racemase_N PF01168.15 EKE42712.1 - 2.2e-45 154.9 0.1 2.6e-45 154.6 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Myosin_TH1 PF06017.8 EKE42712.1 - 0.057 12.7 0.5 0.096 11.9 0.3 1.4 1 0 0 1 1 1 0 Myosin tail Glyco_trans_1_4 PF13692.1 EKE42712.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 MIB_HERC2 PF06701.8 EKE42715.1 - 6e-31 106.2 30.8 7.5e-18 64.2 6.4 2.2 2 0 0 2 2 2 2 Mib_herc2 RimM PF01782.13 EKE42715.1 - 0.53 10.2 2.9 3.1 7.7 0.2 2.7 3 0 0 3 3 3 0 RimM N-terminal domain Fe-ADH PF00465.14 EKE42716.1 - 0.018 13.7 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase AAA PF00004.24 EKE42717.1 - 5.4e-41 139.8 0.3 1.3e-38 132.1 0.0 3.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKE42717.1 - 4.8e-06 26.7 0.1 0.00066 19.8 0.0 3.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EKE42717.1 - 5.9e-05 22.8 0.3 0.0035 17.0 0.0 3.4 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EKE42717.1 - 7.7e-05 21.8 0.0 0.00034 19.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKE42717.1 - 0.0001 23.1 1.9 0.0058 17.4 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EKE42717.1 - 0.00028 20.8 3.0 0.0059 16.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 EKE42717.1 - 0.00051 19.5 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EKE42717.1 - 0.00074 19.5 0.1 0.053 13.5 0.0 2.8 1 1 2 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EKE42717.1 - 0.00092 18.4 0.1 0.0021 17.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 EKE42717.1 - 0.0018 17.9 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_33 PF13671.1 EKE42717.1 - 0.0023 17.8 0.0 0.0093 15.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EKE42717.1 - 0.0026 17.6 0.2 0.037 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EKE42717.1 - 0.003 16.5 0.0 0.0079 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EKE42717.1 - 0.006 16.3 0.2 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EKE42717.1 - 0.0063 15.2 2.4 0.019 13.6 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus ATP-synt_ab PF00006.20 EKE42717.1 - 0.0076 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EKE42717.1 - 0.01 14.9 0.8 0.024 13.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.1 EKE42717.1 - 0.012 15.6 0.1 0.058 13.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EKE42717.1 - 0.013 15.0 0.0 0.048 13.1 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EKE42717.1 - 0.014 15.0 0.2 0.18 11.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EKE42717.1 - 0.02 14.1 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 EKE42717.1 - 0.032 13.8 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKE42717.1 - 0.045 13.1 0.3 0.22 10.8 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EKE42717.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FHA PF00498.21 EKE42717.1 - 0.066 13.3 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 FHA domain NACHT PF05729.7 EKE42717.1 - 0.096 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EKE42717.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.7 4 1 0 4 4 4 0 AAA domain CENP-B_dimeris PF09026.5 EKE42717.1 - 0.67 10.2 9.1 1.9 8.7 6.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain tRNA_U5-meth_tr PF05958.6 EKE42718.1 - 1.3e-23 83.3 0.9 6.6e-22 77.6 0.4 2.5 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EKE42718.1 - 5e-13 48.9 0.1 1.4e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKE42718.1 - 1.4e-09 38.0 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE42718.1 - 2.2e-08 33.6 0.0 4.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EKE42718.1 - 2.9e-06 27.8 0.0 5.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EKE42718.1 - 7.5e-06 25.5 0.2 4.4e-05 23.0 0.0 2.3 3 0 0 3 3 3 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EKE42718.1 - 0.0041 16.2 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EKE42718.1 - 0.0045 16.6 0.1 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EKE42718.1 - 0.0057 16.1 0.1 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 DNA methylase UPF0020 PF01170.13 EKE42718.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EKE42718.1 - 0.0068 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE42718.1 - 0.0096 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EKE42718.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_12 PF08242.7 EKE42718.1 - 0.029 14.8 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EKE42718.1 - 0.048 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.15 EKE42718.1 - 0.071 12.1 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EKE42718.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PGI PF00342.14 EKE42719.1 - 1.1e-216 719.9 1.5 1.3e-216 719.7 1.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.1 EKE42719.1 - 0.58 10.4 0.1 0.58 10.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) DUF3505 PF12013.3 EKE42720.1 - 0.05 13.8 0.7 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) TFIIA PF03153.8 EKE42720.1 - 0.083 12.7 54.4 0.1 12.4 37.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3959 PF13105.1 EKE42720.1 - 0.18 11.0 1.3 0.48 9.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) SH3_9 PF14604.1 EKE42721.1 - 4e-17 61.5 0.9 7.2e-17 60.7 0.6 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKE42721.1 - 5.7e-16 57.6 0.6 1.1e-15 56.7 0.4 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EKE42721.1 - 1.3e-15 57.5 0.0 1.9e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EKE42721.1 - 1.8e-13 49.7 0.1 3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Mito_fiss_reg PF05308.6 EKE42721.1 - 0.083 12.2 5.8 0.04 13.2 1.9 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator EamA PF00892.15 EKE42722.1 - 0.05 13.6 11.6 0.064 13.2 8.0 1.3 1 0 0 1 1 1 0 EamA-like transporter family UPF0546 PF10639.4 EKE42722.1 - 0.062 13.1 1.6 0.1 12.4 1.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 ATP-synt_ab PF00006.20 EKE42724.1 - 1.8e-109 364.2 0.0 3e-109 363.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EKE42724.1 - 5.7e-24 84.7 0.1 1.1e-23 83.8 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EKE42724.1 - 1.1e-13 51.1 2.2 3.2e-13 49.6 1.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RnfC_N PF13375.1 EKE42724.1 - 0.011 15.3 0.2 0.25 11.0 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain AAA_14 PF13173.1 EKE42724.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKE42724.1 - 0.15 11.9 0.0 2.2 8.2 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ATP-sulfurylase PF01747.12 EKE42725.1 - 8.2e-92 306.3 0.0 1.2e-91 305.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EKE42725.1 - 3.3e-57 192.3 0.0 4.9e-57 191.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain L31 PF09784.4 EKE42725.1 - 0.034 14.2 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 LRR_6 PF13516.1 EKE42726.1 - 0.00046 19.9 25.3 9.7 6.6 0.0 9.1 9 0 0 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 EKE42726.1 - 0.0051 16.7 10.2 7.4 7.2 0.0 7.7 8 0 0 8 8 8 1 Leucine rich repeat bPH_3 PF14470.1 EKE42726.1 - 0.0057 16.8 0.5 0.0057 16.8 0.4 3.4 4 1 1 5 5 5 1 Bacterial PH domain LRR_1 PF00560.28 EKE42726.1 - 0.0089 15.9 20.2 12 6.4 0.0 9.4 9 1 1 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.1 EKE42726.1 - 0.025 14.3 19.4 1.2 8.9 0.3 5.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 EKE42726.1 - 0.039 13.5 30.2 0.17 11.5 0.7 6.7 3 2 2 6 6 6 0 Leucine Rich repeats (2 copies) adh_short PF00106.20 EKE42727.1 - 1.9e-10 40.8 0.0 2.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKE42727.1 - 0.00022 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKE42727.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKE42727.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EKE42727.1 - 0.033 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKE42727.1 - 0.036 13.8 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EF-hand_1 PF00036.27 EKE42728.1 - 6.6e-12 43.8 0.0 6.2e-05 22.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EKE42728.1 - 5.4e-11 41.4 0.7 6.4e-05 22.5 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EKE42728.1 - 5.9e-09 35.9 1.9 0.00039 20.5 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EKE42728.1 - 1e-07 31.4 2.2 0.00048 19.6 0.1 3.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EKE42728.1 - 2.4e-07 29.8 0.1 0.0006 19.0 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 EKE42728.1 - 0.0039 16.8 0.3 2.3 8.0 0.0 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Metallophos_2 PF12850.2 EKE42729.1 - 9.2e-11 41.8 0.3 6.9e-10 38.9 0.1 2.4 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EKE42729.1 - 1.2e-07 31.3 8.3 1.1e-06 28.1 5.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EKE42729.1 - 0.099 11.7 2.1 33 3.5 0.0 3.3 3 1 0 4 4 4 0 Metallophosphoesterase, calcineurin superfamily Ras PF00071.17 EKE42730.1 - 9.1e-50 168.2 0.0 1.1e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42730.1 - 1.7e-20 73.7 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKE42730.1 - 2.7e-13 49.5 0.0 3.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKE42730.1 - 1.1e-07 31.8 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKE42730.1 - 1.2e-07 31.4 0.0 8e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EKE42730.1 - 4.4e-05 22.7 0.0 6.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKE42730.1 - 0.00035 19.7 0.0 0.00044 19.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EKE42730.1 - 0.00042 19.5 0.0 0.00072 18.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKE42730.1 - 0.0044 17.1 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EKE42730.1 - 0.0047 16.5 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EKE42730.1 - 0.0061 15.6 0.1 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 Septin NTPase_1 PF03266.10 EKE42730.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 EKE42730.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EKE42730.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EKE42730.1 - 0.013 14.9 0.0 0.034 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 EKE42730.1 - 0.043 13.5 0.1 0.085 12.5 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EKE42730.1 - 0.045 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EKE42730.1 - 0.049 13.1 0.4 0.11 12.0 0.3 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 EKE42730.1 - 0.073 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.14 EKE42730.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EKE42730.1 - 0.094 13.0 0.2 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EKE42730.1 - 0.12 11.0 0.1 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit dNK PF01712.14 EKE42731.1 - 1.7e-08 34.4 6.4 1.9e-05 24.6 0.3 2.2 1 1 0 2 2 2 2 Deoxynucleoside kinase EIAV_GP90 PF00971.13 EKE42731.1 - 0.033 12.6 0.1 0.043 12.2 0.1 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 Gag_spuma PF03276.9 EKE42733.1 - 0.75 8.0 4.5 0.73 8.0 3.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF912 PF06024.7 EKE42734.1 - 0.0002 21.3 0.1 0.00035 20.5 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EKE42734.1 - 0.00047 19.8 0.1 0.00076 19.2 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Nodulin-like PF06813.8 EKE42734.1 - 0.00056 19.2 0.0 0.00084 18.6 0.0 1.1 1 0 0 1 1 1 1 Nodulin-like ASFV_J13L PF05568.6 EKE42734.1 - 0.00087 18.8 0.3 0.0013 18.2 0.2 1.2 1 0 0 1 1 1 1 African swine fever virus J13L protein MFS_Mycoplasma PF07672.8 EKE42734.1 - 0.0066 15.6 0.3 0.0096 15.1 0.2 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter Sigma_reg_N PF13800.1 EKE42734.1 - 0.025 14.6 1.6 0.046 13.7 1.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Peptidase_M56 PF05569.6 EKE42734.1 - 0.045 12.7 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1510 PF07423.6 EKE42734.1 - 0.055 12.8 0.2 0.081 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3753 PF12575.3 EKE42734.1 - 0.059 13.1 5.1 0.14 11.9 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OppC_N PF12911.2 EKE42734.1 - 0.067 12.5 0.6 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C HemY_N PF07219.8 EKE42734.1 - 0.091 12.3 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 HemY protein N-terminus DUF4366 PF14283.1 EKE42734.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3139 PF11337.3 EKE42734.1 - 1.2 9.4 5.5 0.29 11.4 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) TLD PF07534.11 EKE42735.1 - 0.0011 18.9 0.2 0.0048 16.8 0.2 2.1 1 0 0 1 1 1 1 TLD CHASE3 PF05227.8 EKE42735.1 - 0.07 12.8 9.6 0.47 10.1 2.2 2.9 2 1 0 2 2 2 0 CHASE3 domain IncA PF04156.9 EKE42735.1 - 0.2 11.2 22.2 0.19 11.3 1.9 3.1 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 EKE42735.1 - 1.2 8.2 19.4 1.3 8.1 3.3 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Kinesin-relat_1 PF12711.2 EKE42735.1 - 6.2 7.2 18.3 0.06 13.7 0.9 3.7 2 2 1 3 3 3 0 Kinesin motor DivIC PF04977.10 EKE42735.1 - 8.3 5.9 27.7 0.21 11.0 3.8 4.8 3 2 1 4 4 4 0 Septum formation initiator NHL PF01436.16 EKE42736.1 - 1.8e-11 43.3 3.0 0.0016 18.3 0.0 4.8 5 0 0 5 5 5 3 NHL repeat zf-B_box PF00643.19 EKE42736.1 - 2.2e-05 24.2 4.9 2.2e-05 24.2 3.4 4.7 3 1 1 4 4 4 1 B-box zinc finger zf-RING_UBOX PF13445.1 EKE42736.1 - 0.0056 16.3 4.0 0.0056 16.3 2.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger GnsAB PF08178.6 EKE42736.1 - 0.0086 15.7 0.1 0.023 14.3 0.1 1.8 1 0 0 1 1 1 1 GnsA/GnsB family zf-RING_2 PF13639.1 EKE42736.1 - 0.0095 15.7 8.8 0.0095 15.7 6.1 3.7 3 1 0 3 3 3 1 Ring finger domain ABC2_membrane_3 PF12698.2 EKE42737.1 - 0.028 13.4 2.3 0.054 12.5 1.6 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF95 PF01944.12 EKE42737.1 - 0.052 13.1 0.8 0.1 12.2 0.5 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF95 Ponericin PF07442.6 EKE42738.1 - 0.009 15.8 4.2 0.022 14.5 2.9 1.7 1 0 0 1 1 1 1 Ponericin DUF4358 PF14270.1 EKE42738.1 - 0.79 9.6 6.3 0.83 9.5 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Cytochrom_C PF00034.16 EKE42738.1 - 2.1 9.2 9.4 0.36 11.6 1.0 2.6 1 1 1 2 2 2 0 Cytochrome c DUF4446 PF14584.1 EKE42738.1 - 4.3 7.1 6.9 3.7 7.3 3.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) ATC_hydrolase PF14196.1 EKE42738.1 - 4.3 7.7 7.0 2.8 8.3 3.3 1.8 1 1 1 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase RasGEF PF00617.14 EKE42739.1 - 3.5e-05 23.6 8.6 3.5e-05 23.6 5.9 2.4 2 1 0 2 2 2 1 RasGEF domain Rota_NSP3 PF01665.11 EKE42740.1 - 0.046 12.6 5.4 0.053 12.4 3.7 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 GSP_synth PF03738.9 EKE42740.1 - 0.091 13.0 0.6 0.16 12.2 0.4 1.5 1 1 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp DUF2120 PF09893.4 EKE42740.1 - 0.39 10.6 2.6 1.3 9.0 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Xpo1 PF08389.7 EKE42740.1 - 1.3 8.9 6.0 1.5 8.6 2.8 2.0 1 1 1 2 2 2 0 Exportin 1-like protein CAF-1_p150 PF11600.3 EKE42741.1 - 0.93 8.8 79.7 1.1 8.6 55.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBA_4 PF14555.1 EKE42742.1 - 0.0001 21.7 0.1 0.0002 20.8 0.1 1.5 1 1 0 1 1 1 1 UBA-like domain KAR PF15222.1 EKE42742.1 - 0.017 15.1 1.1 0.39 10.8 0.1 2.4 2 0 0 2 2 2 0 Kidney androgen-regulated Cullin_binding PF03556.10 EKE42742.1 - 0.39 10.8 4.6 0.1 12.7 0.7 2.0 2 1 0 2 2 2 0 Cullin binding LRR_5 PF13306.1 EKE42744.1 - 2.8e-68 227.5 67.9 3.6e-23 81.6 5.4 5.9 5 2 1 6 6 6 5 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EKE42744.1 - 1.9e-22 78.7 23.1 1.8e-05 24.3 0.1 9.4 7 3 4 11 11 11 8 Leucine rich repeat PWI PF01480.12 EKE42746.1 - 7.5e-21 74.0 0.5 1.3e-20 73.2 0.3 1.4 1 0 0 1 1 1 1 PWI domain Med2 PF11214.3 EKE42746.1 - 0.012 15.6 0.6 0.019 14.9 0.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Ras PF00071.17 EKE42747.1 - 5.1e-52 175.5 0.0 6.3e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42747.1 - 3.4e-17 63.0 0.0 7.4e-17 61.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKE42747.1 - 4.8e-07 29.1 0.0 5.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKE42747.1 - 0.044 12.9 0.0 0.1 11.6 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RNB PF00773.14 EKE42748.1 - 2.9e-07 30.0 3.6 0.00039 19.8 1.0 3.2 1 1 1 2 2 2 2 RNB domain DUF3276 PF11680.3 EKE42748.1 - 0.036 13.8 0.2 0.036 13.8 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) TLD PF07534.11 EKE42749.1 - 1.2e-06 28.5 28.8 0.0031 17.4 0.7 5.9 5 0 0 5 5 5 4 TLD UPF0029 PF01205.14 EKE42751.1 - 1.7e-29 101.7 0.1 3.6e-29 100.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EKE42751.1 - 5.7e-12 45.5 2.1 5.7e-12 45.5 1.4 2.2 2 1 1 3 3 3 1 RWD domain SR-25 PF10500.4 EKE42752.1 - 0.013 14.9 10.7 0.016 14.6 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MOZART1 PF12554.3 EKE42752.1 - 0.034 13.6 0.5 0.064 12.7 0.3 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF3451 PF11933.3 EKE42752.1 - 4 7.1 12.4 4.1 7.1 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3451) FNIP PF05725.7 EKE42753.1 - 0.043 13.7 3.6 0.71 9.8 0.1 3.9 3 1 0 3 3 3 0 FNIP Repeat Cwf_Cwc_15 PF04889.7 EKE42754.1 - 5.1e-24 85.3 24.7 5.4e-15 55.7 1.9 2.2 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein V_ATPase_I PF01496.14 EKE42754.1 - 6.7 4.4 13.5 7.2 4.3 9.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.11 EKE42754.1 - 9.5 5.5 19.5 8.8 5.6 13.0 1.3 1 1 0 1 1 1 0 Translocation protein Sec62 Myb_DNA-binding PF00249.26 EKE42755.1 - 0.00056 19.9 0.4 0.015 15.3 0.2 2.3 1 1 0 1 1 1 1 Myb-like DNA-binding domain OpgC_C PF10129.4 EKE42756.1 - 0.0015 17.3 0.1 0.0016 17.2 0.1 1.0 1 0 0 1 1 1 1 OpgC protein VMA21 PF09446.5 EKE42756.1 - 0.0088 15.9 2.9 0.011 15.6 2.0 1.2 1 0 0 1 1 1 1 VMA21-like domain PCI PF01399.22 EKE42757.1 - 2.6e-07 30.9 2.1 4.5e-07 30.1 0.3 2.3 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EKE42757.1 - 0.023 14.4 2.7 0.036 13.8 0.1 2.4 3 0 0 3 3 3 0 COP9 signalosome, subunit CSN8 Glyco_hydro_25 PF01183.15 EKE42757.1 - 0.086 12.6 0.3 9.8 5.9 0.2 2.5 1 1 2 3 3 3 0 Glycosyl hydrolases family 25 PAPS_reduct PF01507.14 EKE42758.1 - 0.012 15.4 0.4 0.012 15.4 0.3 2.2 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Gly_kinase PF02595.10 EKE42758.1 - 0.035 12.8 0.9 0.055 12.1 0.6 1.2 1 0 0 1 1 1 0 Glycerate kinase family GAGA_bind PF06217.7 EKE42758.1 - 0.42 10.5 9.9 0.53 10.1 6.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Macoilin PF09726.4 EKE42758.1 - 1.6 6.8 17.1 1.9 6.6 11.9 1.3 1 0 0 1 1 1 0 Transmembrane protein U79_P34 PF03064.11 EKE42758.1 - 3.1 7.2 13.4 4.7 6.6 9.3 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 BAR_3_WASP_bdg PF10456.4 EKE42761.1 - 0.028 13.6 0.1 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Staphostatin_A PF09022.5 EKE42761.1 - 0.038 13.8 0.9 0.061 13.1 0.4 1.6 1 1 0 1 1 1 0 Staphostatin A YkuD PF03734.9 EKE42761.1 - 0.053 13.7 0.6 0.059 13.6 0.1 1.4 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain DUF4358 PF14270.1 EKE42761.1 - 0.17 11.8 3.5 0.16 11.8 1.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) Myb_DNA-bind_3 PF12776.2 EKE42761.1 - 0.26 11.9 2.4 2.6 8.7 0.2 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain LAGLIDADG_1 PF00961.14 EKE42761.1 - 2 9.0 7.8 1.3 9.6 1.1 2.1 2 0 0 2 2 2 0 LAGLIDADG endonuclease Bul1_C PF04426.7 EKE42764.1 - 0.067 12.3 12.6 0.14 11.2 5.1 2.1 1 1 1 2 2 2 0 Bul1 C terminus Exonuc_VII_L PF02601.10 EKE42764.1 - 0.096 11.8 13.7 0.13 11.4 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSCB_C PF07743.8 EKE42764.1 - 0.13 12.7 0.4 0.13 12.7 0.3 4.1 1 1 3 4 4 4 0 HSCB C-terminal oligomerisation domain Reo_sigmaC PF04582.7 EKE42764.1 - 0.2 10.8 2.3 0.26 10.4 0.8 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein WD40_alt PF14077.1 EKE42764.1 - 0.25 11.0 2.8 0.87 9.2 0.2 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF2201 PF09967.4 EKE42764.1 - 0.4 10.6 3.2 4.7 7.2 0.0 2.6 2 1 1 3 3 3 0 VWA-like domain (DUF2201) Ada3 PF10198.4 EKE42764.1 - 0.4 10.4 15.6 0.87 9.3 0.3 3.4 1 1 2 3 3 3 0 Histone acetyltransferases subunit 3 Mto2_bdg PF12808.2 EKE42764.1 - 0.91 9.6 9.5 5.3 7.2 0.3 3.3 2 2 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region AAA_13 PF13166.1 EKE42764.1 - 1.1 7.6 16.3 0.32 9.3 9.1 1.4 1 1 0 1 1 1 0 AAA domain DUF883 PF05957.8 EKE42764.1 - 1.4 9.3 16.9 9.2 6.7 1.9 3.9 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) PLRV_ORF5 PF01690.12 EKE42764.1 - 1.6 7.8 9.9 1.7 7.7 6.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF3573 PF12097.3 EKE42764.1 - 2.4 6.6 8.0 2.7 6.4 5.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) ARS2 PF04959.8 EKE42764.1 - 3.8 7.6 8.1 4.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Arsenite-resistance protein 2 EcoEI_R_C PF08463.5 EKE42764.1 - 4.4 7.1 11.8 5.5 6.8 7.4 1.7 1 1 1 2 2 2 0 EcoEI R protein C-terminal DUF4094 PF13334.1 EKE42764.1 - 5.1 7.5 11.4 6.7 7.1 6.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF16 PF01519.11 EKE42764.1 - 5.3 7.3 22.9 0.27 11.4 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Metallophos PF00149.23 EKE42765.1 - 2.5e-37 128.2 2.1 3.3e-37 127.8 1.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Corona_NS3b PF03053.9 EKE42765.1 - 0.029 13.9 0.2 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 ORF3b coronavirus protein Strumpellin PF10266.4 EKE42768.1 - 2.1e-258 859.9 29.4 8.2e-258 857.9 20.4 1.7 1 1 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DEAD PF00270.24 EKE42769.1 - 2.2e-21 76.0 0.7 7.1e-21 74.4 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE42769.1 - 7.2e-11 41.7 0.1 2.3e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA PF00004.24 EKE42769.1 - 0.047 13.9 8.3 0.026 14.7 2.9 2.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LMBR1 PF04791.11 EKE42771.1 - 1.3e-21 76.7 24.6 2e-21 76.1 17.1 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4328 PF14219.1 EKE42771.1 - 1 8.6 5.0 3.9 6.7 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) PIG-X PF08320.7 EKE42772.1 - 9.5e-22 77.2 0.2 1.8e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 WD40 PF00400.27 EKE42773.1 - 3.6e-77 251.7 35.5 4e-13 48.6 0.5 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EKE42773.1 - 1.8e-08 34.2 0.5 2.9e-08 33.5 0.4 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EKE42773.1 - 9.1e-06 24.0 5.0 0.12 10.5 0.0 4.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EKE42773.1 - 0.045 12.4 5.0 0.24 10.1 0.1 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 EKE42773.1 - 0.086 11.1 0.3 1.3 7.2 0.1 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain UCH PF00443.24 EKE42778.1 - 1.7e-10 40.5 16.6 4e-09 35.9 11.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C28 PF05408.6 EKE42778.1 - 4.2e-06 26.3 0.8 8.3e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Foot-and-mouth virus L-proteinase MAGE PF01454.14 EKE42779.1 - 4.3e-23 81.6 0.8 6.2e-23 81.1 0.6 1.2 1 0 0 1 1 1 1 MAGE family PAP2 PF01569.16 EKE42780.1 - 1.4e-18 66.8 7.2 6.7e-18 64.6 4.9 2.3 1 1 0 1 1 1 1 PAP2 superfamily K1 PF02960.9 EKE42780.1 - 0.079 13.0 7.2 0.18 11.8 0.2 3.3 3 0 0 3 3 3 0 K1 glycoprotein NT-C2 PF10358.4 EKE42781.1 - 5.2e-19 68.1 0.1 5.2e-19 68.1 0.1 3.1 3 1 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EKE42781.1 - 1.1e-07 31.6 0.1 3.7e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 DIL domain PP2C_2 PF13672.1 EKE42782.1 - 1.6e-12 47.2 0.0 2.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE42782.1 - 5.9e-06 26.1 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ribonuclease_T2 PF00445.13 EKE42783.1 - 5e-29 101.2 5.2 6.9e-29 100.8 3.6 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family tRNA-synt_1e PF01406.14 EKE42784.1 - 1.7e-116 388.6 1.3 4.2e-116 387.3 0.9 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EKE42784.1 - 1.6e-09 36.8 0.8 4.6e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EKE42784.1 - 0.00022 19.3 0.5 0.00082 17.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 EKE42784.1 - 0.00058 20.0 0.0 0.003 17.7 0.0 2.2 2 0 0 2 2 2 1 DALR domain Mannitol_dh PF01232.18 EKE42784.1 - 0.066 13.1 0.4 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain Mtc PF03820.12 EKE42784.1 - 0.11 11.1 0.0 0.3 9.7 0.0 1.7 1 0 0 1 1 1 0 Tricarboxylate carrier WD40 PF00400.27 EKE42786.1 - 3.3e-22 77.4 0.1 7.5e-09 35.1 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EKE42786.1 - 0.00038 19.9 0.0 0.0009 18.7 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EKE42786.1 - 0.0026 17.9 0.0 24 5.3 0.0 3.8 4 0 0 4 4 4 1 PQQ-like domain PQQ PF01011.16 EKE42786.1 - 0.0063 16.0 0.1 0.75 9.4 0.0 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat RRM_1 PF00076.17 EKE42787.1 - 4.5e-40 135.1 5.3 3.2e-23 81.1 0.4 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE42787.1 - 6e-28 96.6 0.5 3.2e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42787.1 - 1.5e-18 66.4 1.0 4e-13 49.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EKE42787.1 - 0.00039 19.8 0.3 0.35 10.4 0.1 2.9 2 0 0 2 2 2 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EKE42787.1 - 0.00059 19.5 0.2 0.0016 18.1 0.1 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EKE42787.1 - 0.013 15.0 0.6 0.069 12.7 0.1 2.1 2 0 0 2 2 2 0 Calcipressin TrbH PF07283.6 EKE42787.1 - 0.065 13.0 0.6 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Conjugal transfer protein TrbH Nup35_RRM PF05172.8 EKE42787.1 - 0.13 11.9 1.1 0.66 9.7 0.0 2.5 2 2 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HEAT_2 PF13646.1 EKE42789.1 - 0.00093 19.4 0.1 2.6 8.3 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EKE42789.1 - 0.005 16.8 4.3 10 6.4 0.0 5.5 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 EKE42789.1 - 0.04 13.7 3.7 0.16 11.8 0.0 3.6 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat DNA_gyraseB PF00204.20 EKE42789.1 - 0.042 13.0 0.2 0.23 10.6 0.1 2.3 1 0 0 1 1 1 0 DNA gyrase B HEAT_EZ PF13513.1 EKE42789.1 - 0.48 10.9 2.0 2.7 8.5 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat UME PF08064.8 EKE42789.1 - 3.7 7.5 19.2 6.2 6.8 0.2 6.8 7 1 1 8 8 8 0 UME (NUC010) domain Foie-gras_1 PF11817.3 EKE42790.1 - 0.025 14.0 0.2 0.054 12.9 0.1 1.6 1 0 0 1 1 1 0 Foie gras liver health family 1 Prefoldin PF02996.12 EKE42791.1 - 9.4e-21 73.6 6.8 1.6e-20 72.9 3.4 1.9 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EKE42791.1 - 0.0002 21.0 0.5 0.0002 21.0 0.3 2.9 2 1 0 2 2 2 1 Prefoldin subunit DUF869 PF05911.6 EKE42791.1 - 0.00026 19.3 3.2 0.00034 19.0 2.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 EKE42791.1 - 0.011 15.5 8.1 0.31 10.9 1.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EKE42791.1 - 0.019 14.5 1.6 1.5 8.3 0.5 2.1 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 EKE42791.1 - 0.034 13.6 1.9 0.11 11.9 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF3914 PF13053.1 EKE42791.1 - 0.055 13.6 0.6 0.055 13.6 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3914) Tektin PF03148.9 EKE42791.1 - 0.062 11.8 5.3 0.027 13.0 0.8 2.0 2 0 0 2 2 2 0 Tektin family ATG_C PF09333.6 EKE42791.1 - 0.11 12.6 0.3 3.4 7.8 0.0 2.4 2 1 1 3 3 3 0 ATG C terminal domain TPD52 PF04201.10 EKE42791.1 - 0.18 11.4 5.7 1.5 8.5 1.4 2.1 2 0 0 2 2 2 0 Tumour protein D52 family DUF1664 PF07889.7 EKE42791.1 - 0.22 11.3 7.8 3.1 7.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.4 EKE42791.1 - 0.3 11.0 7.8 2.2 8.2 0.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Med28 PF11594.3 EKE42791.1 - 0.46 10.7 10.8 4.9 7.4 7.5 2.1 1 1 0 1 1 1 0 Mediator complex subunit 28 DUF3450 PF11932.3 EKE42791.1 - 0.51 9.5 4.8 1.8 7.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) XhlA PF10779.4 EKE42791.1 - 0.55 10.1 8.2 0.08 12.8 2.0 2.1 2 1 0 2 2 2 0 Haemolysin XhlA BLOC1_2 PF10046.4 EKE42791.1 - 2.6 8.2 10.4 2.3 8.3 1.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EKE42791.1 - 4.2 7.7 6.2 10 6.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RhoGEF PF00621.15 EKE42792.1 - 5.7e-30 104.5 3.6 5.7e-30 104.5 2.5 3.1 3 1 0 3 3 3 1 RhoGEF domain IQ PF00612.22 EKE42792.1 - 0.0042 16.6 0.0 0.013 15.1 0.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif VWA_2 PF13519.1 EKE42793.1 - 0.017 15.1 0.1 0.39 10.8 0.1 2.4 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF2856 PF11043.3 EKE42793.1 - 0.11 12.6 2.0 6.3 6.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) DUF2046 PF09755.4 EKE42795.1 - 0.079 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) CLN3 PF02487.12 EKE42796.1 - 1.3e-41 142.7 22.5 3.8e-39 134.6 15.6 2.1 1 1 0 1 1 1 1 CLN3 protein YajC PF02699.10 EKE42796.1 - 0.035 13.7 0.1 0.035 13.7 0.1 4.0 3 1 1 4 4 4 0 Preprotein translocase subunit ZZ PF00569.12 EKE42797.1 - 1.4e-10 40.4 5.8 2.6e-10 39.6 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EKE42797.1 - 3.3e-09 36.6 0.0 6.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE42797.1 - 0.016 15.3 1.3 0.037 14.1 0.1 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF454 PF04304.8 EKE42798.1 - 0.69 9.9 0.1 0.69 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF454) zf-DHHC PF01529.15 EKE42799.1 - 2.4e-22 79.1 13.9 2.4e-22 79.1 9.6 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF3899 PF13038.1 EKE42799.1 - 0.083 13.0 2.9 0.12 12.5 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) FA_desaturase PF00487.19 EKE42799.1 - 4.1 6.7 16.4 0.036 13.5 2.6 2.2 1 1 0 2 2 2 0 Fatty acid desaturase AhpC-TSA PF00578.16 EKE42800.1 - 3.3e-28 97.8 0.0 4.3e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKE42800.1 - 2.3e-11 43.4 0.0 2.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EKE42800.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC PWWP PF00855.12 EKE42800.1 - 0.054 13.7 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 PWWP domain NAGidase PF07555.8 EKE42800.1 - 0.06 12.2 0.1 0.085 11.7 0.0 1.4 1 1 0 1 1 1 0 beta-N-acetylglucosaminidase DENN PF02141.16 EKE42801.1 - 6.4e-19 68.3 2.7 1.6e-17 63.8 1.4 2.7 2 1 0 2 2 2 1 DENN (AEX-3) domain C2 PF00168.25 EKE42801.1 - 3.1e-09 36.5 0.1 6.7e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 C2 domain SBF2 PF12335.3 EKE42801.1 - 1.7e-05 24.2 1.5 3.6e-05 23.2 1.0 1.5 1 0 0 1 1 1 1 Myotubularin protein dDENN PF03455.14 EKE42801.1 - 0.0033 17.4 1.5 0.0071 16.4 1.0 1.6 1 0 0 1 1 1 1 dDENN domain FTA4 PF13093.1 EKE42802.1 - 0.025 14.0 2.4 0.03 13.7 1.7 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Orbi_VP5 PF00901.12 EKE42802.1 - 0.11 10.7 1.3 0.12 10.5 0.9 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF755 PF05501.6 EKE42802.1 - 0.29 11.1 10.7 0.47 10.5 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CDC45 PF02724.9 EKE42802.1 - 1.2 7.0 11.0 1.2 7.1 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein TraG-D_C PF12696.2 EKE42802.1 - 6.3 6.6 8.6 33 4.3 6.0 1.9 1 1 0 1 1 1 0 TraM recognition site of TraD and TraG zf-CCCH PF00642.19 EKE42803.1 - 5.4e-08 32.3 12.4 2e-05 24.1 1.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 EKE42803.1 - 0.00036 20.4 0.1 0.00064 19.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42803.1 - 0.0033 17.2 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE42803.1 - 0.049 13.2 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TLD PF07534.11 EKE42806.1 - 4.1e-27 94.8 0.2 7.6e-27 93.9 0.2 1.5 1 0 0 1 1 1 1 TLD BSD PF03909.12 EKE42806.1 - 0.00021 20.9 0.1 0.00055 19.6 0.1 1.7 1 0 0 1 1 1 1 BSD domain UBX PF00789.15 EKE42807.1 - 9.7e-06 25.5 0.1 2.7e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 UBX domain CAF-1_p150 PF11600.3 EKE42807.1 - 0.00017 21.0 38.9 0.00017 21.0 27.0 1.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 EKE42807.1 - 3.3 6.9 20.7 0.32 10.2 9.9 2.0 2 0 0 2 2 2 0 SprA-related family DUF883 PF05957.8 EKE42808.1 - 0.0099 16.2 18.0 0.048 14.0 0.9 5.3 1 1 4 6 6 6 4 Bacterial protein of unknown function (DUF883) AMP-binding PF00501.23 EKE42809.1 - 1.8e-81 273.6 0.0 2.8e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RhoGAP PF00620.22 EKE42810.1 - 3.4e-32 111.1 0.2 2.5e-31 108.3 0.0 2.4 2 1 0 2 2 2 1 RhoGAP domain PH PF00169.24 EKE42810.1 - 0.001 19.2 0.3 0.0027 17.9 0.2 1.7 1 0 0 1 1 1 1 PH domain PhoU PF01895.14 EKE42810.1 - 0.096 13.1 3.0 0.12 12.8 0.4 2.4 2 0 0 2 2 2 0 PhoU domain SlyX PF04102.7 EKE42810.1 - 0.28 11.5 6.1 0.5 10.7 0.5 3.3 2 1 1 3 3 3 0 SlyX IncA PF04156.9 EKE42810.1 - 3.8 7.0 8.6 6.2 6.3 4.7 2.0 2 1 0 2 2 2 0 IncA protein DSPc PF00782.15 EKE42811.1 - 2.4e-29 101.6 0.0 5.9e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 EKE42811.1 - 8.8e-17 60.6 16.4 6.1e-09 35.5 4.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EKE42811.1 - 2.5e-16 58.8 21.7 2.9e-08 33.1 3.7 3.8 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EKE42811.1 - 4e-08 32.1 6.2 0.87 10.0 0.1 5.6 5 1 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.28 EKE42811.1 - 8.2e-08 31.2 16.0 0.011 15.6 0.1 5.8 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 EKE42811.1 - 4.8e-06 26.2 13.3 0.00026 20.6 2.3 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EKE42811.1 - 3.9e-05 23.2 21.2 0.3 11.2 0.3 6.2 6 1 1 7 7 7 4 Leucine Rich repeat Y_phosphatase PF00102.22 EKE42811.1 - 7.6e-05 22.1 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EKE42811.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate AAA_12 PF13087.1 EKE42812.1 - 3.2e-39 134.3 2.3 5.8e-39 133.5 0.4 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EKE42812.1 - 3.3e-29 102.1 0.6 3.3e-29 102.1 0.4 2.2 2 0 0 2 2 2 1 AAA domain DUF2439 PF10382.4 EKE42812.1 - 4.2e-11 42.9 1.3 4.2e-11 42.9 0.9 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.13 EKE42812.1 - 1.3e-09 37.9 2.7 0.021 14.3 0.0 3.8 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 EKE42812.1 - 1.4e-08 34.0 1.2 5.1e-08 32.2 0.0 2.4 3 0 0 3 3 3 1 PIF1-like helicase AAA_30 PF13604.1 EKE42812.1 - 5.5e-07 29.3 0.0 3.2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKE42812.1 - 1.4e-06 27.9 0.0 3.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain zf-GRF PF06839.7 EKE42812.1 - 2.9e-06 27.0 3.2 7.5e-06 25.7 2.2 1.8 1 0 0 1 1 1 1 GRF zinc finger UvrD_C_2 PF13538.1 EKE42812.1 - 0.0021 18.1 0.0 0.0078 16.3 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EKE42812.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 EKE42812.1 - 0.036 13.7 0.0 0.17 11.5 0.0 2.2 1 1 0 1 1 1 0 Helicase Methyltransf_32 PF13679.1 EKE42812.1 - 0.055 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF448 PF04296.8 EKE42812.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF448) MutL PF13941.1 EKE42812.1 - 0.13 10.5 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 MutL protein RabGAP-TBC PF00566.13 EKE42813.1 - 2e-32 112.3 3.9 5.1e-32 111.0 2.7 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nop52 PF05997.7 EKE42815.1 - 1.2e-31 109.8 4.9 1.2e-31 109.8 3.4 1.4 2 0 0 2 2 2 1 Nucleolar protein,Nop52 DUF4239 PF14023.1 EKE42816.1 - 3.6 6.8 7.5 2.3 7.5 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) GM_CSF PF01109.12 EKE42816.1 - 5.5 6.9 8.1 0.22 11.4 0.5 2.4 2 1 0 3 3 3 0 Granulocyte-macrophage colony-stimulating factor CDP-OH_P_transf PF01066.16 EKE42817.1 - 3.4e-10 40.1 12.3 3.4e-10 40.1 8.5 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Intron_maturas2 PF01348.16 EKE42817.1 - 0.029 14.3 0.5 0.064 13.2 0.4 1.5 1 0 0 1 1 1 0 Type II intron maturase RRM_6 PF14259.1 EKE42818.1 - 0.00032 20.6 0.0 0.00081 19.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKE42818.1 - 0.00061 19.3 0.0 0.0021 17.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42818.1 - 0.00084 19.1 0.0 0.0024 17.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.6 EKE42819.1 - 1.5e-130 433.6 0.5 1.9e-130 433.3 0.4 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EKE42819.1 - 4.7e-14 52.2 0.0 7.2e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EKE42819.1 - 2.1e-10 40.1 1.6 2.9e-10 39.6 0.3 1.8 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.1 EKE42819.1 - 1.3e-08 34.8 0.0 4.1e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 EKE42819.1 - 0.0016 17.8 0.1 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA_22 PF13401.1 EKE42819.1 - 0.0061 16.7 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DmpG_comm PF07836.6 EKE42819.1 - 0.12 11.8 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 DmpG-like communication domain DNA_pol_A_exo1 PF01612.15 EKE42821.1 - 0.0039 16.6 2.0 0.0049 16.3 1.4 1.3 1 1 0 1 1 1 1 3'-5' exonuclease VRP3 PF03536.10 EKE42821.1 - 0.0064 15.6 0.1 0.0085 15.2 0.1 1.3 1 0 0 1 1 1 1 Salmonella virulence-associated 28kDa protein THOC7 PF05615.8 EKE42821.1 - 0.016 15.5 5.5 0.02 15.1 3.8 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Tnp_P_element PF12017.3 EKE42821.1 - 0.043 13.0 0.6 0.076 12.2 0.4 1.4 1 0 0 1 1 1 0 Transposase protein ADIP PF11559.3 EKE42821.1 - 0.15 11.9 10.6 0.19 11.6 7.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Herpes_UL92 PF03048.9 EKE42821.1 - 0.23 10.9 3.0 0.34 10.4 2.1 1.3 1 1 0 1 1 1 0 UL92 family XkdW PF09636.5 EKE42821.1 - 0.25 11.2 2.5 0.47 10.3 1.7 1.5 1 1 0 1 1 1 0 XkdW protein DUF3450 PF11932.3 EKE42821.1 - 0.4 9.9 7.2 0.52 9.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 EKE42821.1 - 0.71 9.4 9.9 0.91 9.0 6.8 1.1 1 0 0 1 1 1 0 IncA protein Kinesin-relat_1 PF12711.2 EKE42821.1 - 0.99 9.8 8.4 0.15 12.4 1.3 2.2 2 0 0 2 2 2 0 Kinesin motor FlxA PF14282.1 EKE42821.1 - 3.1 7.7 14.6 1.4 8.8 7.8 1.9 1 1 1 2 2 2 0 FlxA-like protein Myb_DNA-bind_4 PF13837.1 EKE42822.1 - 1.5e-05 25.0 0.1 2.6e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Syntaxin_2 PF14523.1 EKE42822.1 - 0.014 15.4 4.6 0.028 14.4 2.3 2.1 1 1 1 2 2 2 0 Syntaxin-like protein UvsW PF11637.3 EKE42823.1 - 0.012 15.3 0.8 0.012 15.3 0.6 1.9 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW Pkinase_Tyr PF07714.12 EKE42824.1 - 3.7e-48 163.8 0.0 6.5e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE42824.1 - 3e-44 151.1 2.9 7.9e-44 149.7 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain VSP PF03302.8 EKE42824.1 - 1.6 7.3 121.7 0.24 9.9 27.1 4.2 1 1 1 2 2 2 0 Giardia variant-specific surface protein DNA_Packaging PF11053.3 EKE42825.1 - 0.062 12.9 2.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 Terminase DNA packaging enzyme DUF3091 PF11291.3 EKE42825.1 - 7.4 6.6 11.7 0.2 11.6 2.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3091) FCH PF00611.18 EKE42826.1 - 0.00014 22.0 0.1 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Ssl1 PF04056.9 EKE42827.1 - 1.6e-47 161.6 0.2 2.1e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EKE42827.1 - 3.2e-13 49.4 12.5 3.2e-13 49.4 8.7 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EKE42827.1 - 4.8e-12 46.3 0.0 7.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EKE42827.1 - 0.0015 18.2 0.0 0.005 16.5 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Synaptobrevin PF00957.16 EKE42828.1 - 5.6e-22 77.1 2.6 6.8e-22 76.8 1.8 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF3827 PF12877.2 EKE42828.1 - 0.00037 18.7 0.7 0.00037 18.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Rifin_STEVOR PF02009.11 EKE42828.1 - 0.028 14.0 1.1 0.027 14.1 0.8 1.1 1 0 0 1 1 1 0 Rifin/stevor family T2SF PF00482.18 EKE42828.1 - 0.033 14.1 0.1 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F 7tm_2 PF00002.19 EKE42828.1 - 0.052 12.6 1.8 0.058 12.4 1.3 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Shisa PF13908.1 EKE42828.1 - 0.054 13.6 0.2 0.054 13.6 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF912 PF06024.7 EKE42828.1 - 0.074 13.1 0.1 0.086 12.8 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EKE42828.1 - 0.12 12.0 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family GP41 PF00517.12 EKE42828.1 - 0.14 11.6 1.8 0.16 11.4 1.3 1.0 1 0 0 1 1 1 0 Retroviral envelope protein LRR19-TM PF15176.1 EKE42828.1 - 0.34 10.6 3.3 0.46 10.1 2.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Syndecan PF01034.15 EKE42828.1 - 0.62 9.7 2.4 0.89 9.2 1.7 1.2 1 0 0 1 1 1 0 Syndecan domain Baculo_11_kDa PF06143.6 EKE42828.1 - 1 8.7 6.4 0.24 10.7 2.3 1.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF1191 PF06697.7 EKE42828.1 - 1.3 7.8 4.6 2.2 7.0 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) TPPK_C PF12555.3 EKE42828.1 - 1.9 8.3 6.5 0.72 9.6 2.9 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal EphA2_TM PF14575.1 EKE42828.1 - 5.6 7.4 5.8 8.8 6.8 4.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DEAD PF00270.24 EKE42830.1 - 6.2e-44 149.4 0.0 3.6e-43 146.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE42830.1 - 3.6e-21 74.8 0.1 1.5e-20 72.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EKE42830.1 - 0.00017 21.0 0.1 0.00044 19.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C_2 PF13307.1 EKE42830.1 - 0.011 15.7 2.2 0.017 15.1 0.1 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain CBF PF03914.12 EKE42831.1 - 5.6e-22 77.9 0.0 5.6e-22 77.9 0.0 3.6 3 1 0 4 4 4 1 CBF/Mak21 family NOC3p PF07540.6 EKE42831.1 - 7.7e-14 51.7 0.0 4.3e-13 49.3 0.0 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein I_LWEQ PF01608.12 EKE42832.1 - 7.5e-40 136.3 6.6 7.5e-40 136.3 4.6 6.5 4 1 2 6 6 6 3 I/LWEQ domain SPRY PF00622.23 EKE42833.1 - 9.9e-09 35.3 0.4 2.5e-08 34.0 0.3 1.8 1 0 0 1 1 1 1 SPRY domain NTP_transf_2 PF01909.18 EKE42834.1 - 4.7e-07 30.0 0.0 9.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EKE42834.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Cid1 family poly A polymerase Pkinase PF00069.20 EKE42835.1 - 2.1e-60 204.0 0.0 2.9e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42835.1 - 1.5e-28 99.5 0.0 2.8e-28 98.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42835.1 - 7.7e-05 21.7 0.0 0.0017 17.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EKE42835.1 - 0.018 14.6 2.2 0.061 12.8 1.6 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ras PF00071.17 EKE42837.1 - 1.2e-14 53.9 0.9 1.6e-14 53.6 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKE42837.1 - 7.4e-08 32.9 0.0 1.2e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 EKE42837.1 - 0.0007 19.3 0.5 0.00086 19.0 0.4 1.4 1 1 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 EKE42837.1 - 0.0013 18.2 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EKE42837.1 - 0.0014 17.8 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EKE42837.1 - 0.0095 15.8 0.3 0.021 14.7 0.2 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EKE42837.1 - 0.029 14.0 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 EKE42837.1 - 0.031 13.4 0.3 0.23 10.5 0.1 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKE42837.1 - 0.048 13.0 0.1 1.7 7.9 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.24 EKE42837.1 - 0.096 12.8 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKE42837.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EKE42837.1 - 1.6 8.9 5.3 3.4 7.9 3.7 1.6 1 1 0 1 1 1 0 AAA domain Bromo_TP PF07524.8 EKE42838.1 - 7.6e-19 67.2 0.0 1e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EKE42838.1 - 1.3e-12 47.5 0.2 2.8e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term CBFD_NFYB_HMF PF00808.18 EKE42838.1 - 0.01 15.8 0.1 0.023 14.7 0.1 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 EKE42838.1 - 0.073 12.8 0.3 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF2205 PF10224.4 EKE42840.1 - 0.0098 15.4 0.4 0.016 14.7 0.3 1.5 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF2100 PF09873.4 EKE42840.1 - 0.021 14.2 1.0 0.034 13.6 0.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) MtrB PF05440.7 EKE42840.1 - 0.14 12.1 0.6 0.44 10.6 0.1 1.9 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B zf-RING_2 PF13639.1 EKE42841.1 - 6.3e-14 51.5 12.8 1.5e-13 50.3 8.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKE42841.1 - 2.3e-08 33.5 7.4 2.3e-08 33.5 5.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKE42841.1 - 9.3e-08 31.9 10.2 2.4e-07 30.6 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKE42841.1 - 9.8e-08 31.9 9.8 2.6e-07 30.6 6.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKE42841.1 - 1.1e-06 28.1 10.0 2.5e-06 27.0 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKE42841.1 - 2.6e-06 27.0 8.5 5.8e-06 25.8 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EKE42841.1 - 5e-06 26.2 5.4 9.2e-06 25.4 3.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EKE42841.1 - 1.6e-05 24.5 6.7 3.7e-05 23.3 4.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EKE42841.1 - 0.021 14.3 7.7 0.06 12.8 5.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 EKE42841.1 - 0.029 14.2 3.8 0.052 13.3 2.6 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Rtf2 PF04641.7 EKE42841.1 - 0.28 10.3 2.2 0.45 9.6 1.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RINGv PF12906.2 EKE42841.1 - 0.39 10.7 9.3 1 9.4 6.5 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EKE42841.1 - 0.48 10.4 11.7 6.6 6.7 8.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Metallothio_Pro PF02069.11 EKE42841.1 - 0.79 9.5 4.8 2.3 8.1 3.3 1.8 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-C3HC4_4 PF15227.1 EKE42841.1 - 0.96 9.3 15.5 0.068 13.0 6.8 2.2 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EKE42841.1 - 2 8.1 7.8 8.9 6.1 5.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Pkinase_Tyr PF07714.12 EKE42843.1 - 1.1e-55 188.4 0.0 1.5e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE42843.1 - 2.9e-51 174.0 0.1 4.2e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EKE42843.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EKE42844.1 - 8.1e-71 238.2 0.0 8.1e-71 238.2 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42844.1 - 9.2e-57 192.0 0.0 1.8e-56 191.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42844.1 - 1.5e-05 24.1 0.0 5.2e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EKE42844.1 - 4.8e-05 22.5 0.2 8.6e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKE42844.1 - 0.00052 19.8 0.0 0.24 11.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1107 PF06526.7 EKE42844.1 - 0.16 11.8 4.3 6.8 6.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1107) Zip PF02535.17 EKE42845.1 - 0.05 12.6 1.3 0.096 11.6 0.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CBFD_NFYB_HMF PF00808.18 EKE42847.1 - 1.6e-15 56.8 0.2 2.7e-15 56.1 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKE42847.1 - 9.5e-06 25.6 0.1 1.3e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 EKE42847.1 - 0.0063 16.2 0.2 0.0089 15.8 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region TAF4 PF05236.9 EKE42847.1 - 0.014 14.6 1.7 0.021 14.0 1.2 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family efb-c PF12199.3 EKE42847.1 - 0.034 14.0 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal dNK PF01712.14 EKE42848.1 - 3e-10 40.1 2.1 1.6e-07 31.3 0.2 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_28 PF13521.1 EKE42848.1 - 1.5e-08 34.7 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKE42848.1 - 1.1e-07 32.1 0.4 5.2e-06 26.8 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKE42848.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKE42848.1 - 0.0035 18.1 0.2 0.0079 17.0 0.1 1.9 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EKE42848.1 - 0.0042 16.2 0.0 0.045 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKE42848.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EKE42848.1 - 0.032 14.0 0.0 0.18 11.7 0.0 2.0 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.10 EKE42848.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.18 EKE42848.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EKE42848.1 - 0.091 12.2 0.0 0.96 8.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EKE42848.1 - 0.097 12.5 0.4 0.37 10.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EKE42848.1 - 0.13 11.4 0.0 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EKE42848.1 - 0.14 12.4 0.1 0.19 12.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 EKE42848.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain WD40 PF00400.27 EKE42850.1 - 3.7e-08 32.9 0.0 0.0033 17.2 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.6 EKE42850.1 - 0.0063 16.2 0.1 0.1 12.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EKE42850.1 - 0.028 13.5 0.0 0.068 12.2 0.0 1.7 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EKE42850.1 - 0.046 11.5 0.0 0.058 11.1 0.0 1.1 1 0 0 1 1 1 0 IKI3 family PD40 PF07676.7 EKE42850.1 - 0.097 12.3 0.0 21 4.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Skp1 PF01466.14 EKE42851.1 - 0.032 14.2 0.2 0.032 14.2 0.1 3.1 2 1 1 3 3 3 0 Skp1 family, dimerisation domain Tmemb_18A PF09771.4 EKE42851.1 - 0.18 11.8 0.7 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 188 Katanin_con80 PF13925.1 EKE42851.1 - 0.69 9.6 14.6 1 9.0 3.0 3.0 1 1 2 3 3 3 0 con80 domain of Katanin DUF465 PF04325.8 EKE42851.1 - 4.6 7.0 12.3 2.6 7.8 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF465) PRK PF00485.13 EKE42851.1 - 4.8 6.6 9.7 0.93 9.0 1.0 2.3 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family CorA PF01544.13 EKE42851.1 - 7.4 5.5 16.3 1.7 7.6 1.2 2.6 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4285 PF14113.1 EKE42851.1 - 9.3 6.2 6.8 4.4 7.3 2.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4285) DENN PF02141.16 EKE42852.1 - 4.4e-30 104.7 0.6 1.9e-29 102.7 0.3 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 EKE42852.1 - 3.9e-09 36.3 0.1 1.9e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 EKE42852.1 - 5.6e-08 32.7 2.0 1.4e-07 31.4 1.4 1.8 1 0 0 1 1 1 1 dDENN domain POLO_box PF00659.13 EKE42852.1 - 0.046 13.6 0.5 0.21 11.6 0.3 2.2 1 0 0 1 1 1 0 POLO box duplicated region Chromo PF00385.19 EKE42853.1 - 6e-06 25.8 1.0 0.00016 21.3 0.2 3.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Yippee-Mis18 PF03226.9 EKE42854.1 - 0.28 11.2 6.6 31 4.7 4.6 2.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Med10 PF09748.4 EKE42855.1 - 2e-10 40.5 0.1 2.4e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Glycoprotein_B PF00606.13 EKE42855.1 - 0.008 14.2 0.0 0.012 13.7 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B Acetyltransf_7 PF13508.1 EKE42858.1 - 1.7e-09 37.7 1.2 2.7e-09 37.0 0.8 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKE42858.1 - 3.7e-07 30.0 0.4 5.1e-07 29.6 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKE42858.1 - 9.5e-05 22.4 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKE42858.1 - 0.00042 20.1 0.0 0.00069 19.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 EKE42858.1 - 0.0043 16.3 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Acetyltransf_5 PF13444.1 EKE42858.1 - 0.041 14.4 0.1 0.36 11.4 0.1 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKE42858.1 - 0.076 12.8 0.1 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PolyA_pol PF01743.15 EKE42859.1 - 6.7e-26 90.9 0.1 1.4e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EKE42859.1 - 2.4e-06 27.0 0.0 7.5e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EKE42859.1 - 0.022 14.5 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Pyr_redox_2 PF07992.9 EKE42860.1 - 2.8e-14 53.4 1.2 5.1e-14 52.6 0.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EKE42860.1 - 5.1e-12 45.6 1.8 5.1e-12 45.6 1.3 1.9 2 0 0 2 2 1 1 BFD-like [2Fe-2S] binding domain Thi4 PF01946.12 EKE42860.1 - 1e-09 37.8 0.8 2e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.1 EKE42860.1 - 4.5e-09 36.6 0.5 0.00067 19.7 0.1 2.7 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKE42860.1 - 9.5e-08 32.3 3.8 0.0016 18.7 0.3 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKE42860.1 - 1.2e-07 31.6 0.4 6.5e-06 26.0 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EKE42860.1 - 3.6e-06 26.3 2.2 5e-06 25.8 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EKE42860.1 - 2.1e-05 23.2 0.6 2.1e-05 23.2 0.4 2.6 2 1 2 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.19 EKE42860.1 - 0.00027 19.9 1.9 0.00027 19.9 1.3 2.5 3 1 1 4 4 4 1 FAD binding domain DAO PF01266.19 EKE42860.1 - 0.00069 18.6 0.7 0.00069 18.6 0.5 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKE42860.1 - 0.00085 19.1 1.0 0.0078 16.0 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EKE42860.1 - 0.00099 18.1 0.5 0.0019 17.2 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EKE42860.1 - 0.0014 18.8 0.4 1.2 9.3 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 EKE42860.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Trp_halogenase PF04820.9 EKE42860.1 - 0.079 11.5 0.4 0.12 10.9 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EKE42860.1 - 0.79 8.7 5.1 0.48 9.4 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain MFS_1 PF07690.11 EKE42861.1 - 4.5e-38 130.8 21.5 2.2e-23 82.5 5.5 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKE42861.1 - 7.1e-12 44.6 15.0 2.1e-06 26.5 2.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EKE42861.1 - 2.8e-08 32.6 30.4 1.2e-07 30.5 4.6 3.1 2 1 0 2 2 2 2 MFS/sugar transport protein Mem_trans PF03547.13 EKE42861.1 - 6.2e-05 21.4 3.5 0.0078 14.5 0.6 2.5 1 1 1 2 2 2 2 Membrane transport protein RhoGAP PF00620.22 EKE42862.1 - 1.3e-13 50.7 0.0 3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Baculo_PEP_C PF04513.7 EKE42863.1 - 0.016 15.0 2.3 0.016 15.0 1.6 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YhjQ PF06564.7 EKE42863.1 - 0.02 14.2 0.3 0.028 13.7 0.2 1.2 1 0 0 1 1 1 0 YhjQ protein Exonuc_VII_L PF02601.10 EKE42863.1 - 0.026 13.7 11.2 0.034 13.3 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.3 EKE42863.1 - 0.3 8.3 18.0 0.34 8.1 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.7 EKE42863.1 - 0.47 10.8 13.6 0.076 13.4 1.6 2.9 2 2 1 3 3 3 0 SlyX DUF3573 PF12097.3 EKE42863.1 - 0.76 8.3 10.6 1.1 7.8 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4407 PF14362.1 EKE42863.1 - 0.84 8.5 12.6 1.1 8.1 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lipase_GDSL PF00657.17 EKE42863.1 - 0.97 9.2 4.5 0.65 9.7 0.7 1.9 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Uds1 PF15456.1 EKE42863.1 - 1.7 8.6 16.2 0.13 12.2 3.3 2.2 1 1 1 2 2 2 0 Up-regulated During Septation LCD1 PF09798.4 EKE42863.1 - 2.5 6.0 19.2 3.4 5.5 13.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein V_ATPase_I PF01496.14 EKE42863.1 - 3.5 5.3 14.6 4.7 4.9 10.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EKE42863.1 - 5.8 5.7 17.9 7.3 5.4 12.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AATF-Che1 PF13339.1 EKE42863.1 - 7.9 6.6 16.9 34 4.5 11.7 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF724 PF05266.9 EKE42863.1 - 9.1 5.8 25.3 0.19 11.3 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TCTP PF00838.12 EKE42864.1 - 5.6e-46 156.5 6.2 6.2e-46 156.3 4.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CBM_4_9 PF02018.12 EKE42865.1 - 1e-07 32.0 0.4 1e-07 32.0 0.3 3.2 4 0 0 4 4 4 1 Carbohydrate binding domain Cofilin_ADF PF00241.15 EKE42865.1 - 0.038 13.8 1.0 3.4 7.5 0.0 3.0 3 0 0 3 3 3 0 Cofilin/tropomyosin-type actin-binding protein PKD PF00801.15 EKE42865.1 - 0.072 12.8 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 PKD domain Peptidase_M18 PF02127.10 EKE42866.1 - 1.2e-112 376.5 0.0 2.2e-112 375.7 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EKE42866.1 - 0.0028 16.4 0.1 0.16 10.6 0.0 2.1 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Utp12 PF04003.7 EKE42868.1 - 4.2e-13 49.1 0.8 7.3e-13 48.3 0.6 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EKE42868.1 - 0.095 12.6 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PQ-loop PF04193.9 EKE42871.1 - 1.1e-16 60.0 9.8 1.7e-09 37.0 0.3 3.5 4 0 0 4 4 4 2 PQ loop repeat Alkyl_sulf_dimr PF14863.1 EKE42872.1 - 2.7e-54 183.2 0.2 4.3e-54 182.5 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 EKE42872.1 - 6.3e-16 58.4 0.3 1.3e-15 57.4 0.2 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 EKE42872.1 - 7e-12 45.4 0.0 4.8e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKE42872.1 - 4.3e-06 26.4 0.0 7.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_11 PF13414.1 EKE42872.1 - 0.0012 18.4 0.5 0.0027 17.3 0.3 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 EKE42872.1 - 0.021 15.5 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EKE42872.1 - 0.042 13.9 0.1 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 RdgC PF04381.7 EKE42872.1 - 0.051 12.5 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC DUF162 PF02589.10 EKE42873.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 YlbD_coat PF14071.1 EKE42873.1 - 0.071 13.1 0.8 0.45 10.5 0.0 2.7 2 0 0 2 2 2 0 Putative coat protein P53_C PF11619.3 EKE42873.1 - 0.097 12.4 0.6 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain TFIID-31kDa PF02291.10 EKE42874.1 - 4.6e-11 42.6 0.3 3.4e-08 33.3 0.2 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DBR1 PF05011.8 EKE42874.1 - 0.053 13.4 0.2 0.073 12.9 0.2 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain DUF3113 PF11310.3 EKE42875.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) DUF92 PF01940.11 EKE42876.1 - 2.4e-36 124.9 5.1 3e-36 124.6 3.5 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Gpi16 PF04113.9 EKE42877.1 - 8.7e-19 66.9 1.8 6.5e-18 64.0 0.2 2.3 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component Mre11_DNA_bind PF04152.9 EKE42878.1 - 0.87 9.4 9.4 2.9 7.7 6.5 1.8 1 1 0 1 1 1 0 Mre11 DNA-binding presumed domain FDF PF09532.5 EKE42878.1 - 1.9 9.0 16.5 2.8 8.5 11.4 1.1 1 0 0 1 1 1 0 FDF domain Silic_transp PF03842.8 EKE42878.1 - 6.8 4.6 5.8 7.3 4.5 4.0 1.0 1 0 0 1 1 1 0 Silicon transporter zf-C3HC4_3 PF13920.1 EKE42879.1 - 2.1e-10 40.1 7.0 3.2e-10 39.4 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKE42879.1 - 2.8e-10 40.0 10.3 5.5e-10 39.1 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE42879.1 - 9e-09 35.0 10.6 1.5e-08 34.3 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKE42879.1 - 1.8e-08 33.8 9.9 3.6e-08 32.9 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE42879.1 - 1e-07 31.7 10.3 2.1e-07 30.7 7.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EKE42879.1 - 1.7e-06 27.6 11.3 2.3e-06 27.1 7.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EKE42879.1 - 3.8e-05 23.3 4.5 3.8e-05 23.3 3.1 2.9 3 0 0 3 3 2 1 RING-type zinc-finger zf-P11 PF03854.9 EKE42879.1 - 0.0025 17.2 6.7 0.0054 16.1 4.7 1.6 1 1 0 1 1 1 1 P-11 zinc finger muHD PF10291.4 EKE42879.1 - 0.037 13.2 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ALS2CR8 PF15299.1 EKE42879.1 - 0.043 13.3 2.2 0.053 13.1 1.5 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 zf-Nse PF11789.3 EKE42879.1 - 0.084 12.4 8.8 0.19 11.2 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YdjO PF14169.1 EKE42879.1 - 0.13 11.7 1.7 0.27 10.7 0.1 2.3 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_6 PF14835.1 EKE42879.1 - 0.21 11.4 8.2 1 9.1 4.8 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-TFIIIC PF12660.2 EKE42879.1 - 0.24 11.2 6.6 0.44 10.4 4.6 1.4 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_4 PF14570.1 EKE42879.1 - 0.35 10.4 8.0 0.37 10.4 4.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EKE42879.1 - 0.37 10.6 6.0 0.8 9.5 4.1 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EKE42879.1 - 0.51 9.9 11.3 11 5.6 7.7 2.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EKE42879.1 - 0.56 9.7 11.8 0.73 9.3 7.5 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Prim_Zn_Ribbon PF08273.7 EKE42879.1 - 0.59 10.2 2.8 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase PolC_DP2 PF03833.8 EKE42879.1 - 0.79 7.2 3.1 0.86 7.1 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-rbx1 PF12678.2 EKE42879.1 - 0.83 9.8 8.6 2.2 8.4 5.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger DZR PF12773.2 EKE42879.1 - 1.1 9.1 7.7 4.6 7.1 5.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon FYVE_2 PF02318.11 EKE42879.1 - 1.8 8.4 7.5 2.2 8.2 4.8 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger TF_Zn_Ribbon PF08271.7 EKE42879.1 - 2 7.7 6.9 1.9 7.8 1.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_3 PF14369.1 EKE42879.1 - 3.8 7.5 5.8 0.8 9.7 0.5 2.2 2 0 0 2 2 2 0 zinc-finger zf-ribbon_3 PF13248.1 EKE42879.1 - 4 6.7 7.1 0.8 8.9 1.2 2.5 2 1 0 2 2 2 0 zinc-ribbon domain FYVE PF01363.16 EKE42879.1 - 5.4 6.9 9.6 36 4.3 6.6 2.4 1 1 0 1 1 1 0 FYVE zinc finger DUF3184 PF11380.3 EKE42882.1 - 2.6e-05 22.4 0.0 0.0021 16.0 0.0 3.1 2 1 2 4 4 4 2 Protein of unknown function (DUF3184) RNA_pol_Rpb5_C PF01191.14 EKE42883.1 - 7.9e-35 118.3 0.4 1.5e-34 117.4 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EKE42883.1 - 7.9e-20 71.0 0.0 1.9e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain POTRA_2 PF08479.6 EKE42883.1 - 0.032 13.8 0.1 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 POTRA domain, ShlB-type Rad50_zn_hook PF04423.9 EKE42883.1 - 0.12 11.8 0.5 0.29 10.6 0.2 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF3897 PF13036.1 EKE42884.1 - 0.69 9.5 3.1 0.87 9.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3897) FAT PF02259.18 EKE42885.1 - 3.1e-43 148.1 24.5 3.1e-43 148.1 17.0 3.8 3 2 0 3 3 3 2 FAT domain Rapamycin_bind PF08771.6 EKE42885.1 - 1.3e-19 70.1 0.8 1.3e-19 70.1 0.6 5.9 6 0 0 6 6 6 1 Rapamycin binding domain DUF3385 PF11865.3 EKE42885.1 - 1.7e-19 70.2 0.6 1.7e-19 70.2 0.4 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.1 EKE42885.1 - 1.1e-05 25.6 0.0 2.4 8.4 0.0 6.6 6 2 1 7 7 7 1 HEAT repeats HEAT PF02985.17 EKE42885.1 - 0.033 14.2 0.0 26 5.2 0.0 5.8 8 0 0 8 8 8 0 HEAT repeat RICTOR_V PF14668.1 EKE42885.1 - 0.038 13.9 2.7 15 5.6 0.0 5.0 5 1 1 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 U3snoRNP10 PF12397.3 EKE42885.1 - 0.79 9.6 6.3 0.59 10.0 0.2 3.3 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 Myb_DNA-binding PF00249.26 EKE42887.1 - 9e-26 89.6 3.0 2.4e-13 49.8 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKE42887.1 - 3.3e-19 68.7 5.7 2.8e-12 46.5 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EKE42887.1 - 0.4 10.8 5.3 0.68 10.1 0.8 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUSP PF06337.7 EKE42889.1 - 0.08 13.3 0.9 0.25 11.7 0.1 2.2 2 0 0 2 2 2 0 DUSP domain DUF4522 PF15022.1 EKE42890.1 - 0.99 9.1 4.5 14 5.4 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4522) CH PF00307.26 EKE42891.1 - 1.5e-11 44.3 4.8 8.4e-09 35.4 0.0 3.2 3 1 0 3 3 3 2 Calponin homology (CH) domain Caldesmon PF02029.10 EKE42891.1 - 0.00039 18.9 28.7 0.00054 18.5 19.9 1.2 1 0 0 1 1 1 1 Caldesmon SOBP PF15279.1 EKE42891.1 - 0.074 13.4 24.6 0.1 12.9 17.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 EKE42891.1 - 0.71 8.0 51.2 0.97 7.5 35.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 EKE42891.1 - 2.9 7.2 56.7 4.6 6.5 39.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 EKE42892.1 - 2.5e-15 56.3 0.8 2.5e-15 56.3 0.5 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42892.1 - 7.1e-10 38.3 0.2 9.6e-10 37.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKE42892.1 - 2.5e-08 33.9 0.5 6.9e-08 32.4 0.1 1.8 2 0 0 2 2 2 1 FHA domain DUF2782 PF11191.3 EKE42892.1 - 0.014 15.3 0.4 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) Ceramidase_alk PF04734.8 EKE42892.1 - 0.05 11.4 0.0 0.068 11.0 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase DSHCT PF08148.7 EKE42893.1 - 2.8e-51 173.3 0.0 2.8e-51 173.3 0.0 2.0 3 0 0 3 3 3 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 EKE42893.1 - 4.4e-44 150.6 0.9 9.1e-44 149.6 0.6 1.5 1 1 0 1 1 1 1 rRNA-processing arch domain WD40 PF00400.27 EKE42894.1 - 1.5e-31 107.1 10.7 1.7e-07 30.8 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Sof1 PF04158.9 EKE42894.1 - 4.3e-14 52.3 0.6 4.3e-14 52.3 0.4 1.6 2 0 0 2 2 2 1 Sof1-like domain BBS2_Mid PF14783.1 EKE42894.1 - 0.014 15.1 0.1 7.6 6.3 0.0 3.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EKE42894.1 - 0.018 13.2 0.0 0.031 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PHZA_PHZB PF03284.8 EKE42894.1 - 0.024 13.7 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B RhoGAP PF00620.22 EKE42895.1 - 4.1e-29 101.1 0.0 1.3e-28 99.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain Vps54 PF07928.7 EKE42895.1 - 0.067 13.3 0.6 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Vps54-like protein Fumerase PF05681.9 EKE42896.1 - 2.3e-86 289.2 0.0 3e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 EKE42896.1 - 1.4e-74 249.7 0.0 2e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus Gemini_AL1 PF00799.15 EKE42897.1 - 0.0046 16.7 1.0 0.012 15.4 0.7 1.8 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain MobB PF03205.9 EKE42897.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EKE42897.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Cullin PF00888.17 EKE42898.1 - 8e-81 272.3 38.4 8e-81 272.3 26.6 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EKE42898.1 - 1.1e-21 76.4 0.9 1.1e-21 76.4 0.6 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.14 EKE42898.1 - 0.0012 18.4 0.4 2.2 8.0 0.1 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB DUF953 PF06110.6 EKE42899.1 - 0.0007 19.0 0.2 0.0029 17.0 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF953) V-SNARE_C PF12352.3 EKE42900.1 - 1.8e-09 37.5 2.9 4.6e-09 36.2 1.8 1.8 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EKE42900.1 - 5.6e-06 25.9 0.6 8.6e-06 25.3 0.5 1.3 1 0 0 1 1 1 1 Sec20 Anoctamin PF04547.7 EKE42900.1 - 0.00011 21.0 0.0 0.00012 20.8 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF607 PF04678.8 EKE42900.1 - 0.0017 18.3 0.1 0.0019 18.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF607 MFS_2 PF13347.1 EKE42900.1 - 0.004 15.6 0.1 0.0048 15.3 0.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein OATP PF03137.15 EKE42900.1 - 0.0055 14.8 0.1 0.0055 14.8 0.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF904 PF06005.7 EKE42900.1 - 0.0098 16.1 1.3 0.016 15.4 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF2031 PF09592.5 EKE42900.1 - 0.012 14.8 0.2 0.013 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Fusion_gly PF00523.13 EKE42900.1 - 0.015 13.4 1.2 0.16 9.9 0.1 2.0 1 1 0 2 2 2 0 Fusion glycoprotein F0 GAS PF13851.1 EKE42900.1 - 0.03 13.5 3.1 0.035 13.3 2.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CemA PF03040.9 EKE42900.1 - 0.034 13.7 0.7 0.04 13.5 0.5 1.1 1 0 0 1 1 1 0 CemA family ETRAMP PF09716.5 EKE42900.1 - 0.091 12.7 2.4 0.4 10.6 1.6 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Alkyl_sulf_C PF14864.1 EKE42900.1 - 0.11 12.4 0.4 0.15 12.0 0.3 1.1 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Synaptobrevin PF00957.16 EKE42900.1 - 0.11 12.0 5.1 0.22 11.1 3.5 1.6 1 1 0 1 1 1 0 Synaptobrevin DUF3671 PF12420.3 EKE42900.1 - 0.11 12.4 4.8 0.2 11.6 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function TBCA PF02970.11 EKE42900.1 - 0.15 12.1 2.2 0.38 10.8 0.5 1.9 1 1 1 2 2 2 0 Tubulin binding cofactor A SNARE PF05739.14 EKE42900.1 - 0.16 11.7 3.3 0.17 11.5 0.8 2.1 1 1 2 3 3 3 0 SNARE domain Snapin_Pallidin PF14712.1 EKE42900.1 - 0.16 12.2 2.3 0.22 11.8 1.6 1.2 1 0 0 1 1 1 0 Snapin/Pallidin ADIP PF11559.3 EKE42900.1 - 0.4 10.5 4.6 0.49 10.2 3.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding T2SF PF00482.18 EKE42900.1 - 0.42 10.5 2.0 0.67 9.8 1.3 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Rifin_STEVOR PF02009.11 EKE42900.1 - 2.4 7.7 7.3 5.9 6.4 5.1 1.6 1 1 0 1 1 1 0 Rifin/stevor family Sigma_reg_N PF13800.1 EKE42900.1 - 5 7.2 8.1 10 6.2 5.6 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3885 PF13021.1 EKE42901.1 - 0.16 11.7 1.6 8.6 6.1 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Synaptobrevin PF00957.16 EKE42902.1 - 8.8e-22 76.5 8.6 1.1e-21 76.2 6.0 1.1 1 0 0 1 1 1 1 Synaptobrevin TMEM154 PF15102.1 EKE42902.1 - 0.00031 20.4 1.9 0.00035 20.2 1.3 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 EKE42902.1 - 0.00072 19.5 3.0 0.00083 19.3 2.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) OppC_N PF12911.2 EKE42902.1 - 0.0022 17.3 2.3 0.0049 16.2 1.6 1.6 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C DUF4064 PF13273.1 EKE42902.1 - 0.004 17.2 1.5 0.0048 16.9 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) BPD_transp_1 PF00528.17 EKE42902.1 - 0.0062 16.0 1.0 0.0071 15.8 0.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Shisa PF13908.1 EKE42902.1 - 0.007 16.5 0.4 0.0076 16.4 0.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.1 EKE42902.1 - 0.0089 15.4 1.1 0.0097 15.3 0.8 1.1 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain DUF4310 PF14187.1 EKE42902.1 - 0.01 15.3 1.1 0.011 15.2 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) BatD PF13584.1 EKE42902.1 - 0.016 13.8 1.0 0.017 13.7 0.7 1.0 1 0 0 1 1 1 0 Oxygen tolerance YukC PF10140.4 EKE42902.1 - 0.017 13.6 1.3 0.019 13.5 0.9 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF1191 PF06697.7 EKE42902.1 - 0.017 13.9 4.8 0.025 13.3 3.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) TRP PF06011.7 EKE42902.1 - 0.024 13.2 1.4 0.023 13.2 1.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Rifin_STEVOR PF02009.11 EKE42902.1 - 0.038 13.6 6.8 0.05 13.2 4.7 1.2 1 0 0 1 1 1 0 Rifin/stevor family 7tm_2 PF00002.19 EKE42902.1 - 0.065 12.3 5.2 0.071 12.1 3.6 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Hanta_G2 PF01561.11 EKE42902.1 - 0.065 11.6 1.2 0.069 11.5 0.8 1.0 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 Baculo_E56 PF04639.7 EKE42902.1 - 0.066 11.8 1.1 0.069 11.7 0.7 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Rhabdo_glycop PF00974.13 EKE42902.1 - 0.074 11.2 0.9 0.076 11.2 0.6 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein TBCA PF02970.11 EKE42902.1 - 0.083 12.9 0.4 0.1 12.6 0.3 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor A GP41 PF00517.12 EKE42902.1 - 0.084 12.4 6.5 0.098 12.2 4.5 1.1 1 0 0 1 1 1 0 Retroviral envelope protein EphA2_TM PF14575.1 EKE42902.1 - 0.087 13.2 4.5 0.18 12.2 3.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.4 EKE42902.1 - 0.14 11.8 0.1 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2077 PF09850.4 EKE42902.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Use1 PF09753.4 EKE42902.1 - 0.25 10.7 4.3 0.28 10.5 3.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Mid2 PF04478.7 EKE42902.1 - 0.31 10.4 5.2 0.36 10.2 3.5 1.2 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF687 PF05095.7 EKE42902.1 - 0.41 8.9 3.0 0.45 8.8 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Corona_S2 PF01601.11 EKE42902.1 - 0.79 7.7 5.8 0.86 7.6 4.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Glycophorin_A PF01102.13 EKE42902.1 - 0.79 9.4 2.8 0.96 9.2 2.0 1.2 1 1 0 1 1 1 0 Glycophorin A DUF3827 PF12877.2 EKE42902.1 - 1.1 7.2 13.5 1.2 7.2 9.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) Baculo_11_kDa PF06143.6 EKE42902.1 - 1.2 8.5 10.0 2.3 7.6 6.9 1.7 1 1 0 1 1 1 0 Baculovirus 11 kDa family L1R_F9L PF02442.12 EKE42902.1 - 2.5 7.5 8.7 3.8 6.9 6.0 1.5 1 1 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses AP-5_subunit_s1 PF15001.1 EKE42903.1 - 3e-34 118.6 0.8 4.2e-34 118.1 0.5 1.2 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 Clat_adaptor_s PF01217.15 EKE42903.1 - 0.0035 17.0 1.3 0.0053 16.4 0.9 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AAA_35 PF14516.1 EKE42903.1 - 0.015 13.9 0.3 0.25 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain PTCB-BRCT PF12738.2 EKE42905.1 - 3.6e-16 58.7 0.0 4.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKE42905.1 - 1e-12 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Spore_YhaL PF14147.1 EKE42905.1 - 0.055 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL Pkinase PF00069.20 EKE42906.1 - 1.8e-34 119.0 0.1 2.2e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42906.1 - 8.4e-14 51.2 0.0 9.1e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKE42906.1 - 0.00027 20.7 0.0 0.00079 19.2 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EKE42906.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NPV_P10 PF05531.7 EKE42908.1 - 0.049 13.8 10.2 1.5 9.1 0.2 4.3 3 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Interferon PF00143.14 EKE42908.1 - 0.074 12.9 6.7 0.033 14.0 2.6 1.9 1 1 1 2 2 2 0 Interferon alpha/beta domain UNC-50 PF05216.8 EKE42909.1 - 8.4e-28 97.1 30.2 1.1e-27 96.7 20.9 1.1 1 0 0 1 1 1 1 UNC-50 family EF-hand_4 PF12763.2 EKE42910.1 - 3.4e-06 26.7 0.8 0.00044 19.9 0.3 2.9 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 EKE42910.1 - 0.00018 21.0 4.8 0.0023 17.5 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EKE42910.1 - 0.00035 20.6 0.1 0.1 12.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EKE42910.1 - 0.00076 18.6 8.4 0.031 13.5 2.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EKE42910.1 - 0.0058 15.9 5.0 0.1 11.9 2.9 2.8 2 0 0 2 2 2 1 EF hand 4HB_MCP_1 PF12729.2 EKE42910.1 - 0.038 13.3 1.1 0.072 12.4 0.8 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction EF-hand_6 PF13405.1 EKE42910.1 - 0.071 13.0 5.9 0.13 12.1 1.5 2.8 2 1 0 2 2 2 0 EF-hand domain vWA-TerF-like PF10138.4 EKE42913.1 - 8.4e-05 22.4 0.3 0.00015 21.6 0.2 1.4 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EKE42913.1 - 0.00038 20.2 1.0 0.00056 19.6 0.7 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EKE42913.1 - 0.0041 17.2 0.0 0.0047 17.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EKE42913.1 - 0.044 12.9 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein AAA_5 PF07728.9 EKE42914.1 - 2e-130 429.3 6.1 1.1e-23 83.4 0.0 11.3 10 2 2 12 12 10 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKE42914.1 - 2.7e-31 107.9 0.0 2.3e-09 36.9 0.0 8.2 10 0 0 10 10 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EKE42914.1 - 3e-29 101.8 8.8 4.3e-05 23.7 0.1 8.1 8 0 0 8 8 6 5 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKE42914.1 - 3.2e-25 88.7 1.2 0.0012 19.0 0.1 7.8 6 1 0 6 6 6 5 AAA domain AAA_17 PF13207.1 EKE42914.1 - 6.7e-23 81.7 7.9 0.0053 17.5 0.0 8.5 8 0 0 8 8 6 6 AAA domain AAA_16 PF13191.1 EKE42914.1 - 4.8e-18 65.8 0.0 0.0082 16.1 0.0 7.2 6 0 0 6 6 6 3 AAA ATPase domain AAA_33 PF13671.1 EKE42914.1 - 4e-16 59.1 0.0 0.033 14.0 0.0 6.9 6 1 0 6 6 6 3 AAA domain Miro PF08477.8 EKE42914.1 - 8.7e-16 58.4 1.6 0.19 12.2 0.0 7.7 6 0 0 6 6 6 4 Miro-like protein RNA_helicase PF00910.17 EKE42914.1 - 5.4e-15 55.4 4.2 0.18 12.0 0.0 8.0 7 0 0 7 7 6 3 RNA helicase ABC_tran PF00005.22 EKE42914.1 - 7.3e-15 55.4 12.8 0.011 15.9 0.0 8.0 7 0 0 7 7 6 3 ABC transporter PduV-EutP PF10662.4 EKE42914.1 - 1.2e-13 50.7 6.6 0.0033 16.9 0.0 6.5 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EKE42914.1 - 1.1e-12 47.4 1.8 0.061 12.2 0.0 5.4 5 0 0 5 5 5 4 Type II/IV secretion system protein Sigma54_activat PF00158.21 EKE42914.1 - 1.1e-12 47.6 0.7 0.13 11.6 0.0 6.7 7 0 0 7 7 6 3 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EKE42914.1 - 2e-12 47.3 0.2 0.2 11.7 0.0 6.6 5 1 1 6 6 6 4 Sigma-54 interaction domain AAA_30 PF13604.1 EKE42914.1 - 2.8e-12 46.6 0.0 0.36 10.3 0.0 6.9 7 0 0 7 7 7 3 AAA domain Zeta_toxin PF06414.7 EKE42914.1 - 4.3e-12 45.5 0.0 0.4 9.7 0.0 7.1 7 0 0 7 7 7 3 Zeta toxin UPF0079 PF02367.12 EKE42914.1 - 9.4e-12 44.6 1.0 0.96 9.0 0.0 6.6 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EKE42914.1 - 1.3e-11 44.0 0.0 0.1 12.3 0.0 5.4 5 0 0 5 5 5 3 Part of AAA domain AAA_18 PF13238.1 EKE42914.1 - 1.3e-11 44.8 46.5 0.0023 18.2 0.0 10.8 10 1 1 11 11 7 5 AAA domain Mg_chelatase PF01078.16 EKE42914.1 - 2.1e-11 43.3 2.8 0.51 9.4 0.1 8.4 9 0 0 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EKE42914.1 - 2.6e-11 43.7 0.3 0.76 9.7 0.0 6.9 6 0 0 6 6 6 3 AAA domain RuvB_N PF05496.7 EKE42914.1 - 4.6e-11 42.2 2.7 0.13 11.2 0.0 6.2 6 0 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EKE42914.1 - 2.8e-10 39.5 0.1 0.17 11.4 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain MobB PF03205.9 EKE42914.1 - 3.2e-10 39.8 3.7 0.44 10.2 0.0 6.2 6 0 0 6 6 5 3 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EKE42914.1 - 5.1e-10 39.2 6.5 0.11 12.2 0.0 7.1 8 0 0 8 8 7 2 NACHT domain AAA_25 PF13481.1 EKE42914.1 - 6.9e-10 38.6 0.0 0.24 10.7 0.0 6.2 7 0 0 7 7 7 3 AAA domain Viral_helicase1 PF01443.13 EKE42914.1 - 8.7e-08 31.9 0.2 3.1 7.2 0.0 6.2 6 1 1 7 7 7 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EKE42914.1 - 3.3e-07 29.9 3.0 0.046 13.1 0.0 4.6 5 0 0 5 5 5 3 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 EKE42914.1 - 2.1e-06 27.4 0.1 0.38 10.2 0.0 5.4 5 0 0 5 5 5 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EKE42914.1 - 6.5e-06 25.6 0.0 12 5.3 0.0 5.6 5 0 0 5 5 5 0 IstB-like ATP binding protein CPT PF07931.7 EKE42914.1 - 0.00084 19.0 1.9 15 5.1 0.0 5.9 7 0 0 7 7 6 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 EKE42915.1 - 6.3e-18 65.2 7.4 6.3e-18 65.2 5.2 2.1 1 1 1 2 2 2 1 AAA domain DEAD PF00270.24 EKE42915.1 - 9.1e-05 22.0 2.7 0.035 13.6 0.3 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_30 PF13604.1 EKE42915.1 - 9.9e-05 22.0 0.1 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EKE42915.1 - 0.00011 21.3 1.5 0.014 14.3 0.3 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EKE42915.1 - 0.00048 19.4 3.9 0.0059 15.8 0.5 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA_19 PF13245.1 EKE42915.1 - 0.00088 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Helicase_RecD PF05127.9 EKE42915.1 - 0.0013 18.4 3.0 0.09 12.4 0.1 2.9 3 0 0 3 3 3 1 Helicase AAA_5 PF07728.9 EKE42915.1 - 0.0028 17.3 0.1 0.0086 15.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.10 EKE42915.1 - 0.0082 15.9 13.0 0.048 13.4 6.4 3.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 EKE42915.1 - 0.017 14.7 0.2 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EKE42915.1 - 0.046 13.8 5.9 0.08 13.0 0.0 3.9 4 1 1 5 5 5 0 AAA domain AAA_25 PF13481.1 EKE42915.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EKE42915.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKE42915.1 - 8.6 7.2 7.5 1.8 9.4 0.3 3.4 2 2 0 2 2 2 0 AAA domain COQ7 PF03232.8 EKE42917.1 - 0.042 13.3 2.5 0.047 13.1 1.7 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF3901 PF13040.1 EKE42917.1 - 0.07 12.4 14.2 0.13 11.5 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) SpoIISA_toxin PF14171.1 EKE42917.1 - 0.28 10.4 2.7 0.28 10.3 1.9 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Myb_CC_LHEQLE PF14379.1 EKE42917.1 - 1.2 8.7 7.2 0.96 9.0 3.8 1.7 1 1 1 2 2 2 0 MYB-CC type transfactor, LHEQLE motif UPF0242 PF06785.6 EKE42917.1 - 1.5 7.4 6.6 1.5 7.4 4.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF2203 PF09969.4 EKE42917.1 - 3 8.0 6.2 3.2 8.0 4.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Tnp_P_element PF12017.3 EKE42917.1 - 3.2 6.9 5.0 3.1 6.9 3.5 1.0 1 0 0 1 1 1 0 Transposase protein CCDC14 PF15254.1 EKE42917.1 - 3.4 5.9 13.1 3.4 5.9 9.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DivIC PF04977.10 EKE42917.1 - 4.8 6.7 12.2 6.1 6.4 8.5 1.2 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EKE42917.1 - 5.8 6.4 11.7 5.8 6.4 8.1 1.0 1 0 0 1 1 1 0 IncA protein CENP-H PF05837.7 EKE42917.1 - 5.8 7.1 10.6 6.3 7.0 7.3 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AAA_13 PF13166.1 EKE42917.1 - 6.7 5.0 13.5 6.6 5.0 9.4 1.0 1 0 0 1 1 1 0 AAA domain HSF_DNA-bind PF00447.12 EKE42918.1 - 7.2e-29 100.0 0.1 7.2e-29 100.0 0.1 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding SlyX PF04102.7 EKE42918.1 - 5.9e-06 26.5 3.5 1.1e-05 25.6 2.4 1.4 1 0 0 1 1 1 1 SlyX FTA4 PF13093.1 EKE42918.1 - 0.0008 18.9 0.3 0.0008 18.9 0.2 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Laminin_I PF06008.9 EKE42918.1 - 0.006 15.9 1.1 0.0082 15.4 0.7 1.1 1 0 0 1 1 1 1 Laminin Domain I DUF4460 PF14687.1 EKE42918.1 - 0.025 14.3 0.5 0.063 13.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DUF3450 PF11932.3 EKE42918.1 - 0.026 13.7 3.2 0.038 13.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 EKE42918.1 - 0.086 10.6 2.6 0.11 10.2 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Microtub_assoc PF07989.6 EKE42918.1 - 0.14 11.9 3.8 0.11 12.3 0.6 2.1 1 1 1 2 2 2 0 Microtubule associated LSM PF01423.17 EKE42919.1 - 4.1e-13 48.6 0.1 4.9e-13 48.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain DUF1336 PF07059.7 EKE42919.1 - 0.043 13.2 0.0 0.052 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) DUF2362 PF10154.4 EKE42920.1 - 0.0017 17.1 1.3 0.0088 14.7 0.3 1.9 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2362) DUF4477 PF14780.1 EKE42921.1 - 7.1e-05 22.2 0.6 0.00025 20.4 0.1 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4477) TPR_MLP1_2 PF07926.7 EKE42921.1 - 0.005 16.5 0.4 0.005 16.5 0.3 2.8 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein GGDEF PF00990.16 EKE42921.1 - 0.054 13.0 0.1 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 GGDEF domain EF-hand_4 PF12763.2 EKE42922.1 - 0.0049 16.5 1.8 0.31 10.7 0.0 3.2 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand PBS_linker_poly PF00427.16 EKE42922.1 - 0.064 12.9 2.7 5 6.7 0.0 2.8 2 1 1 3 3 3 0 Phycobilisome Linker polypeptide Choline_transpo PF04515.7 EKE42922.1 - 0.25 10.0 0.5 0.34 9.5 0.4 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter WD40 PF00400.27 EKE42923.1 - 1.4e-06 27.9 9.0 1.6e-05 24.5 0.0 4.7 5 1 0 5 5 5 1 WD domain, G-beta repeat DUF2963 PF11178.3 EKE42923.1 - 0.069 12.5 0.5 12 5.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) Synaptobrevin PF00957.16 EKE42924.1 - 2.4e-14 52.6 0.1 2.4e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 EKE42924.1 - 1.8e-09 37.0 0.1 3.5e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SEN1_N PF12726.2 EKE42924.1 - 0.0034 15.5 1.3 0.004 15.2 0.9 1.2 1 0 0 1 1 1 1 SEN1 N terminal Sec20 PF03908.8 EKE42924.1 - 0.0079 15.8 0.5 0.02 14.5 0.3 1.7 1 0 0 1 1 1 1 Sec20 Pkinase_Tyr PF07714.12 EKE42926.1 - 4.6e-24 84.8 0.0 5.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE42926.1 - 6.4e-22 77.9 0.1 1.1e-21 77.1 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EKE42926.1 - 0.012 14.9 0.2 0.028 13.7 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EKE42926.1 - 0.027 13.4 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like cEGF PF12662.2 EKE42927.1 - 0.00027 20.4 5.6 0.016 14.8 0.8 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like DUF4215 PF13948.1 EKE42927.1 - 1.9 8.7 12.2 18 5.6 3.9 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) FXa_inhibition PF14670.1 EKE42927.1 - 7.8 6.7 15.3 0.79 9.8 2.9 3.0 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site Glyco_transf_41 PF13844.1 EKE42928.1 - 0.2 9.5 1.0 0.25 9.2 0.7 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 zf-3CxxC PF13695.1 EKE42928.1 - 0.22 11.7 5.1 0.61 10.3 3.6 2.1 1 1 0 1 1 1 0 Zinc-binding domain eIF2A PF08662.6 EKE42929.1 - 3.5e-41 141.0 0.1 2e-39 135.3 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EKE42929.1 - 0.0029 17.4 0.0 1.8 8.5 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EKE42929.1 - 0.031 13.0 0.2 1.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Coatomer WD associated region PNP_UDP_1 PF01048.15 EKE42930.1 - 3e-26 91.8 0.0 3.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HCaRG PF07258.9 EKE42931.1 - 3.2e-12 46.3 1.6 3.9e-12 46.0 1.1 1.1 1 0 0 1 1 1 1 HCaRG protein Guanylate_kin PF00625.16 EKE42931.1 - 0.008 15.6 1.6 0.36 10.2 0.4 2.6 1 1 2 3 3 3 2 Guanylate kinase DEAD PF00270.24 EKE42932.1 - 4.1e-38 130.5 0.4 7e-38 129.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKE42932.1 - 2.6e-27 94.4 0.1 5.6e-27 93.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EKE42932.1 - 0.0081 15.2 1.4 0.028 13.4 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.9 EKE42932.1 - 0.029 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_19 PF13245.1 EKE42932.1 - 0.071 12.8 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EKE42932.1 - 0.088 12.3 0.1 0.17 11.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain PQQ_2 PF13360.1 EKE42933.1 - 8.2e-07 28.7 0.0 1.2e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 EKE42933.1 - 3.2e-06 27.2 0.3 0.3 11.4 0.0 4.2 5 0 0 5 5 5 2 PQQ-like domain DUF778 PF05608.7 EKE42933.1 - 0.058 13.3 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) VCBS PF13517.1 EKE42933.1 - 0.15 12.4 0.2 13 6.2 0.0 3.3 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.16 EKE42933.1 - 0.59 9.7 7.4 3.7 7.2 0.1 3.7 5 0 0 5 5 5 0 PQQ enzyme repeat UCH PF00443.24 EKE42934.1 - 5.8e-32 110.8 2.5 1.2e-31 109.8 1.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EKE42934.1 - 5.3e-19 67.4 0.7 5.9e-09 35.4 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EKE42934.1 - 1.1e-17 63.8 7.1 8.1e-14 51.4 0.0 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EKE42934.1 - 4.6e-09 36.1 3.1 1.1e-07 31.5 2.1 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EKE42934.1 - 0.00071 19.0 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 UBA-like domain CUE PF02845.11 EKE42934.1 - 0.01 15.3 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 CUE domain zf-B_box PF00643.19 EKE42934.1 - 2.7 7.9 8.3 0.44 10.4 2.7 1.9 2 0 0 2 2 2 0 B-box zinc finger SMC_N PF02463.14 EKE42936.1 - 5.5e-43 146.7 85.5 7.9e-33 113.5 0.3 4.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKE42936.1 - 3.5e-25 88.3 1.4 1.9e-24 85.9 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EKE42936.1 - 3.4e-16 60.1 17.1 3.4e-16 60.1 11.9 8.6 1 1 4 5 5 5 1 AAA domain AAA_21 PF13304.1 EKE42936.1 - 1.5e-12 48.1 16.8 6.8e-08 32.8 2.4 5.0 2 2 2 4 4 4 2 AAA domain AAA_29 PF13555.1 EKE42936.1 - 2.2e-05 23.8 0.0 4.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain LMBR1 PF04791.11 EKE42936.1 - 0.0015 17.2 4.4 0.0015 17.2 3.0 4.9 2 2 1 4 4 4 1 LMBR1-like membrane protein PAS_10 PF13596.1 EKE42937.1 - 0.029 14.6 2.2 0.086 13.1 0.0 2.9 3 1 0 3 3 3 0 PAS domain Pkinase PF00069.20 EKE42937.1 - 0.2 10.8 12.3 0.014 14.5 2.1 2.8 1 1 2 3 3 3 0 Protein kinase domain Rapamycin_bind PF08771.6 EKE42939.1 - 0.027 14.5 0.0 0.027 14.5 0.0 4.1 4 0 0 4 4 4 0 Rapamycin binding domain zf-CCHC_2 PF13696.1 EKE42940.1 - 8.4e-08 31.5 5.3 1.9e-07 30.4 3.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Rtf2 PF04641.7 EKE42940.1 - 9.6e-05 21.7 10.5 0.00027 20.2 6.6 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-CCHC PF00098.18 EKE42940.1 - 0.00022 20.9 3.4 0.00022 20.9 2.4 2.9 3 0 0 3 3 3 1 Zinc knuckle zf-C3HC4_3 PF13920.1 EKE42940.1 - 0.012 15.2 13.6 0.012 15.2 9.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKE42940.1 - 0.3 10.8 24.6 0.042 13.5 11.6 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.1 EKE42940.1 - 3.6 7.4 10.5 0.58 9.9 4.5 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PP2C PF00481.16 EKE42941.1 - 1e-33 116.8 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKE42941.1 - 4.3e-08 32.8 0.0 8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKE42941.1 - 0.0083 15.8 0.0 0.12 12.0 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Methyltransf_31 PF13847.1 EKE42942.1 - 8.3e-09 35.2 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKE42942.1 - 1.8e-08 33.8 0.0 2.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EKE42942.1 - 3.8e-08 33.3 0.0 6.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKE42942.1 - 4.8e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKE42942.1 - 5e-07 30.2 0.0 8.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKE42942.1 - 2.7e-06 26.8 0.2 4.3e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EKE42942.1 - 0.00049 19.7 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 EKE42942.1 - 0.00093 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EKE42942.1 - 0.0013 17.4 0.0 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EKE42942.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain TehB PF03848.9 EKE42942.1 - 0.0057 15.8 0.1 0.014 14.5 0.1 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 EKE42942.1 - 0.018 14.1 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EKE42942.1 - 0.021 14.3 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EKE42942.1 - 0.053 12.9 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DREV PF05219.7 EKE42942.1 - 0.062 12.1 0.0 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase CbiD PF01888.12 EKE42942.1 - 0.075 11.9 0.3 0.16 10.9 0.2 1.5 2 0 0 2 2 2 0 CbiD Methyltransf_24 PF13578.1 EKE42942.1 - 0.11 13.3 0.0 0.31 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CH PF00307.26 EKE42943.1 - 6.2e-31 106.6 1.1 1.3e-14 54.1 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKE42943.1 - 0.022 14.3 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain Pkinase PF00069.20 EKE42944.1 - 1.4e-27 96.5 0.1 2.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE42944.1 - 4.6e-13 48.8 0.0 7.8e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE42944.1 - 5.4e-06 25.5 0.0 9.5e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKE42944.1 - 0.0019 18.0 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EKE42944.1 - 0.0089 15.1 0.2 0.017 14.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKE42944.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL E1-E2_ATPase PF00122.15 EKE42945.1 - 1.6e-28 99.3 0.2 4.3e-28 97.9 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKE42945.1 - 4.2e-23 82.8 0.0 1.2e-22 81.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKE42945.1 - 4.5e-20 72.6 0.0 8.9e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKE42945.1 - 2.5e-10 40.1 0.2 1.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKE42945.1 - 1.1e-05 25.1 6.6 0.004 16.7 0.1 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKE42945.1 - 0.00076 18.9 0.0 0.025 14.0 0.0 3.2 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus DUF2529 PF10740.4 EKE42945.1 - 0.0097 15.3 1.3 3.4 7.0 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF2529) MMPL PF03176.10 EKE42946.1 - 3.3e-63 213.4 7.4 4.7e-32 111.0 0.9 2.3 2 0 0 2 2 2 2 MMPL family Orbi_NS3 PF01616.11 EKE42946.1 - 2.8 6.8 7.9 0.26 10.2 0.2 2.6 3 0 0 3 3 3 0 Orbivirus NS3 Ank_2 PF12796.2 EKE42947.1 - 1.9e-17 63.3 0.1 1.8e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKE42947.1 - 3.2e-13 49.4 0.2 7.3e-07 29.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EKE42947.1 - 6.3e-13 47.8 0.8 2.6e-07 30.1 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EKE42947.1 - 4.3e-12 46.1 0.1 4.5e-05 23.8 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKE42947.1 - 2.2e-10 39.7 0.1 0.00084 19.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Patatin PF01734.17 EKE42947.1 - 4.1e-06 26.8 0.0 1.8e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Chorein_N PF12624.2 EKE42948.1 - 4.5e-31 106.8 1.1 4.5e-31 106.8 0.8 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EKE42948.1 - 2.7e-06 27.4 0.0 8.9e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Peptidase_M8 PF01457.11 EKE42949.1 - 0.0096 14.3 4.7 0.012 13.9 3.3 1.2 1 0 0 1 1 1 1 Leishmanolysin ADH_N PF08240.7 EKE42949.1 - 0.14 11.9 0.5 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain TLD PF07534.11 EKE42950.1 - 1.2e-10 41.4 0.4 4.3e-10 39.7 0.3 1.9 1 0 0 1 1 1 1 TLD Uricase PF01014.13 EKE42950.1 - 0.17 11.9 7.6 0.24 11.4 4.7 1.7 1 1 0 1 1 1 0 Uricase DUF3735 PF12537.3 EKE42950.1 - 2.6 8.1 6.2 3.6 7.7 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) BTB PF00651.26 EKE42951.1 - 2.7e-08 33.7 1.7 5.7e-06 26.2 0.0 3.6 2 1 1 3 3 3 1 BTB/POZ domain PRP21_like_P PF12230.3 EKE42951.1 - 0.0016 18.0 0.3 0.0016 18.0 0.2 2.4 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein zf-C2HC_2 PF13913.1 EKE42951.1 - 0.019 14.6 0.1 0.051 13.2 0.1 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Sgf11 PF08209.6 EKE42951.1 - 0.1 11.9 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) WD40 PF00400.27 EKE42952.1 - 0.027 14.3 0.2 7.6 6.5 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat ubiquitin PF00240.18 EKE42953.1 - 1.6e-21 75.4 0.2 1.8e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKE42953.1 - 1.5e-11 43.8 0.1 1.5e-11 43.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKE42953.1 - 7.4e-07 29.3 0.0 5.5e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EKE42953.1 - 0.083 12.7 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4492 PF14899.1 EKE42954.1 - 0.11 12.0 1.6 0.18 11.3 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) SH3_9 PF14604.1 EKE42955.1 - 1.8e-15 56.2 1.2 2.9e-15 55.5 0.8 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKE42955.1 - 7.6e-14 50.9 0.2 1.3e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKE42955.1 - 7e-12 44.5 1.1 1.4e-11 43.5 0.8 1.6 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EKE42955.1 - 2.1e-05 24.1 8.0 0.00025 20.6 5.5 2.0 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EKE42955.1 - 3.4e-05 23.3 5.1 0.0002 20.8 1.1 2.3 2 0 0 2 2 2 1 Arfaptin-like domain SH3_3 PF08239.6 EKE42955.1 - 0.056 13.6 0.8 0.1 12.7 0.6 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain RRM_1 PF00076.17 EKE42956.1 - 4.6e-16 58.2 0.0 7.9e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE42956.1 - 5e-12 45.6 0.0 8.9e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE42956.1 - 2.6e-11 43.1 0.0 3.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKE42956.1 - 0.021 14.5 0.1 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 EphA2_TM PF14575.1 EKE42957.1 - 0.0057 17.0 1.2 0.18 12.2 0.3 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF3671 PF12420.3 EKE42957.1 - 0.012 15.5 0.8 0.019 14.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function 7TM_GPCR_Sri PF10327.4 EKE42957.1 - 0.019 13.9 1.3 0.023 13.6 0.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri LRR19-TM PF15176.1 EKE42957.1 - 5.9 6.6 6.2 5.1 6.8 0.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain LRR_4 PF12799.2 EKE42958.1 - 4.8e-11 42.0 13.4 2.8e-06 26.7 0.3 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKE42958.1 - 4.2e-10 39.2 8.7 0.00031 20.4 0.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EKE42958.1 - 0.035 14.1 9.4 13 6.2 0.0 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EKE42958.1 - 0.042 14.0 8.0 30 5.4 0.2 5.3 4 0 0 4 4 4 0 Leucine rich repeat RIX1 PF08167.7 EKE42959.1 - 0.99 9.0 11.1 4.5 6.9 0.0 4.4 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis Ins134_P3_kin PF05770.6 EKE42960.1 - 2.8e-35 121.8 0.7 4e-35 121.3 0.5 1.2 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase ATP-grasp_3 PF02655.9 EKE42960.1 - 1.2e-05 25.2 0.7 4.1e-05 23.4 0.1 2.1 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EKE42960.1 - 4e-05 23.4 0.0 0.0002 21.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain TTL PF03133.10 EKE42960.1 - 0.00064 18.7 2.8 0.015 14.1 0.1 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_Ter PF15632.1 EKE42960.1 - 0.01 14.6 0.0 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF1308 PF07000.6 EKE42960.1 - 0.12 10.9 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) CALCOCO1 PF07888.6 EKE42962.1 - 0.00028 19.3 18.8 0.00035 19.0 13.0 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2265 PF10023.4 EKE42962.1 - 0.055 12.6 4.2 0.023 13.8 0.8 1.7 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) DUF1804 PF08822.6 EKE42962.1 - 0.17 11.6 2.9 0.28 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF4320 PF14208.1 EKE42962.1 - 0.44 10.5 4.0 0.26 11.2 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) DUF4294 PF14127.1 EKE42962.1 - 1.9 8.0 12.1 0.19 11.3 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) DUF4200 PF13863.1 EKE42962.1 - 2 8.3 32.8 2.2 8.2 5.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Rota_NSP4 PF01452.11 EKE42962.1 - 5.7 6.2 11.7 0.57 9.5 3.8 2.1 1 1 0 2 2 2 0 Rotavirus non structural protein Fib_alpha PF08702.5 EKE42962.1 - 7 6.7 18.7 7.8 6.6 1.7 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3810 PF12725.2 EKE42962.1 - 7.3 5.3 9.9 0.96 8.2 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF3496 PF12001.3 EKE42962.1 - 9.9 6.4 12.7 0.41 10.9 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) HMG_box PF00505.14 EKE42963.1 - 1.2e-06 28.6 2.1 3.7e-06 27.1 0.0 2.5 2 2 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKE42963.1 - 3.1e-06 27.4 0.0 9.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.20 EKE42964.1 - 4.2e-05 22.8 2.3 0.15 11.1 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 EKE42964.1 - 0.0036 16.3 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.21 EKE42965.1 - 2.4e-05 24.3 6.6 5.2e-05 23.2 0.1 3.6 2 1 2 4 4 4 1 FHA domain KAR PF15222.1 EKE42965.1 - 0.032 14.3 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Kidney androgen-regulated TIG PF01833.19 EKE42966.1 - 1.5e-09 37.6 1.0 2.7e-09 36.8 0.7 1.4 1 0 0 1 1 1 1 IPT/TIG domain ubiquitin PF00240.18 EKE42966.1 - 3.3e-06 26.3 0.3 7.2e-06 25.3 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EKE42966.1 - 0.0071 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S3_C PF00189.15 EKE42966.1 - 0.018 15.2 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain zf-C3HC4 PF00097.20 EKE42967.1 - 0.0036 16.9 4.6 0.027 14.1 2.3 3.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE42967.1 - 0.022 14.5 6.9 0.18 11.6 4.8 2.7 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EKE42967.1 - 0.23 11.5 11.5 0.018 15.0 2.7 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EKE42967.1 - 0.48 10.2 10.5 0.039 13.6 3.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 EKE42967.1 - 2.3 7.9 14.6 0.3 10.8 6.3 2.6 2 0 0 2 2 2 0 zinc-RING finger domain Peptidase_C1 PF00112.18 EKE42968.1 - 5.8e-11 42.6 4.7 3.6e-10 40.0 3.2 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Tetraspannin PF00335.15 EKE42969.1 - 1.9e-07 30.5 11.9 2.8e-07 30.0 8.2 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF898 PF05987.8 EKE42969.1 - 0.66 8.7 8.1 2.7 6.7 4.6 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) NfeD PF01957.13 EKE42969.1 - 0.84 9.7 9.4 0.63 10.1 1.7 2.8 2 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4064 PF13273.1 EKE42969.1 - 1.9 8.6 11.0 4.3 7.4 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF1129 PF06570.6 EKE42969.1 - 2.1 7.5 8.1 1.5 8.1 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DoxX_2 PF13564.1 EKE42969.1 - 6.2 6.8 10.0 2.5 8.1 4.2 2.3 2 1 0 2 2 2 0 DoxX-like family Pmp3 PF01679.12 EKE42970.1 - 1.2e-15 56.9 3.9 1.5e-15 56.5 2.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0118 PF01594.11 EKE42970.1 - 0.02 13.9 2.6 0.02 13.8 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF20 PTPS_related PF10131.4 EKE42970.1 - 0.08 11.0 2.0 0.091 10.8 1.4 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Trep_Strep PF09605.5 EKE42970.1 - 0.14 11.8 3.8 0.16 11.6 2.6 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2427 PF10348.4 EKE42970.1 - 0.23 11.0 1.8 0.26 10.8 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF3270 PF11674.3 EKE42970.1 - 1 9.3 5.3 1 9.4 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) PhaG_MnhG_YufB PF03334.9 EKE42970.1 - 1.6 8.8 4.6 2.1 8.4 0.1 2.3 1 1 1 2 2 2 0 Na+/H+ antiporter subunit DUF3317 PF11779.3 EKE42970.1 - 7.6 6.0 11.7 0.46 9.9 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3317) Synaptobrevin PF00957.16 EKE42971.1 - 2.2e-21 75.2 0.2 3.5e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EKE42971.1 - 1.6e-06 27.5 0.0 4.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec20 PF03908.8 EKE42971.1 - 0.00075 19.1 0.1 0.0016 18.0 0.1 1.5 1 0 0 1 1 1 1 Sec20 Laminin_I PF06008.9 EKE42971.1 - 0.025 13.9 1.0 0.059 12.6 0.6 1.6 1 1 1 2 2 2 0 Laminin Domain I DUF948 PF06103.6 EKE42971.1 - 0.28 11.0 2.9 8.4 6.3 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2515 PF10720.4 EKE42972.1 - 0.04 12.8 5.5 0.025 13.4 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2515) DUF4131 PF13567.1 EKE42973.1 - 2.1 7.6 7.0 21 4.4 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Sigma_reg_N PF13800.1 EKE42973.1 - 6.2 6.9 10.7 6 6.9 0.0 3.6 3 1 0 3 3 3 0 Sigma factor regulator N-terminal RNA_pol_Rpb2_6 PF00562.23 EKE42974.1 - 1.8e-121 405.5 1.0 2.5e-120 401.7 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EKE42974.1 - 4.2e-37 127.0 0.7 7.6e-37 126.2 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EKE42974.1 - 2.4e-30 104.6 0.0 8.4e-30 102.8 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EKE42974.1 - 4.9e-22 78.2 0.3 9.3e-22 77.3 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EKE42974.1 - 4.2e-21 74.4 0.0 9.1e-21 73.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EKE42974.1 - 8.7e-18 64.0 1.9 9e-18 63.9 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.8 EKE42974.1 - 6.3e-16 57.9 0.0 2.7e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 SWIRM PF04433.12 EKE42975.1 - 2.1e-21 75.8 1.1 3.4e-21 75.1 0.1 1.9 2 0 0 2 2 2 1 SWIRM domain RDD PF06271.7 EKE42976.1 - 1.8 8.4 12.3 4.3e+02 0.7 8.6 2.3 1 1 0 1 1 1 0 RDD family DUF4064 PF13273.1 EKE42976.1 - 8 6.6 11.7 0.79 9.8 1.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Ribosomal_L29 PF00831.18 EKE42977.1 - 5.3e-18 64.4 4.7 3.5e-17 61.8 0.2 2.2 2 0 0 2 2 2 2 Ribosomal L29 protein L27 PF02828.11 EKE42977.1 - 0.097 12.3 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 L27 domain NADH_oxidored PF08040.6 EKE42978.1 - 0.082 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit Yeast-kill-tox PF09207.6 EKE42979.1 - 0.032 14.6 0.1 0.057 13.8 0.1 1.4 1 0 0 1 1 1 0 Yeast killer toxin NPR3 PF03666.8 EKE42979.1 - 0.15 10.5 0.2 0.2 10.1 0.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_C1 PF00112.18 EKE42980.1 - 7.3e-25 88.1 6.2 1.3e-24 87.2 4.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE42980.1 - 4.7e-09 36.3 1.3 1.2e-08 35.0 0.9 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) TPR_11 PF13414.1 EKE42981.1 - 0.0011 18.6 0.3 0.0031 17.1 0.2 1.8 1 0 0 1 1 1 1 TPR repeat Sugar_tr PF00083.19 EKE42982.1 - 1.3e-38 132.7 34.0 1.4e-20 73.3 8.3 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKE42982.1 - 2.6e-32 111.9 31.1 1.2e-29 103.1 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKE42982.1 - 1.4e-09 36.9 31.8 4.9e-05 21.9 4.4 3.4 1 1 2 3 3 3 3 MFS/sugar transport protein DUF4492 PF14899.1 EKE42982.1 - 0.054 13.0 0.7 0.054 13.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) RhoGAP PF00620.22 EKE42983.1 - 4.7e-20 71.7 0.2 4.8e-19 68.4 0.2 2.8 1 1 0 1 1 1 1 RhoGAP domain DUF2968 PF11180.3 EKE42983.1 - 1.7 7.9 8.2 0.44 9.8 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) RhoGEF PF00621.15 EKE42984.1 - 3.4e-05 23.8 0.3 3.4e-05 23.8 0.2 2.0 3 0 0 3 3 3 1 RhoGEF domain hDGE_amylase PF14701.1 EKE42984.1 - 0.026 13.4 0.2 0.039 12.8 0.1 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme PH PF00169.24 EKE42984.1 - 0.057 13.6 0.6 0.15 12.3 0.4 1.8 1 1 0 1 1 1 0 PH domain Rad33 PF08730.5 EKE42984.1 - 0.088 12.2 0.6 0.14 11.6 0.2 1.5 2 0 0 2 2 2 0 Rad33 ABC_tran PF00005.22 EKE42985.1 - 2.7e-29 102.1 0.0 8.9e-29 100.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EKE42985.1 - 2.7e-14 52.9 27.4 2.7e-14 52.9 19.0 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 EKE42985.1 - 4.2e-11 43.3 3.2 1.1e-06 28.8 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EKE42985.1 - 0.00019 20.8 0.4 0.0014 18.1 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EKE42985.1 - 0.0097 15.1 0.0 0.022 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EKE42985.1 - 0.045 14.0 0.2 0.045 14.0 0.2 3.1 4 1 0 4 4 4 0 AAA domain Adaptin_N PF01602.15 EKE42986.1 - 1.3e-72 244.8 21.5 2.2e-72 244.0 14.9 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EKE42986.1 - 2.1e-20 73.0 1.0 6.7e-20 71.4 0.7 1.9 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EKE42986.1 - 2e-08 34.3 0.1 0.0026 18.0 0.0 4.4 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EKE42986.1 - 1.4e-06 27.8 1.9 0.3 11.2 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat TFCD_C PF12612.3 EKE42986.1 - 0.0058 16.0 6.6 0.051 12.9 0.6 3.4 3 1 0 3 3 3 2 Tubulin folding cofactor D C terminal Inhibitor_G39P PF11417.3 EKE42986.1 - 0.038 13.9 0.4 17 5.4 0.1 3.0 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P CENP-X PF09415.5 EKE42988.1 - 0.017 14.9 0.6 0.017 14.9 0.4 4.0 4 0 0 4 4 4 0 CENP-S associating Centromere protein X Peptidase_M24 PF00557.19 EKE42989.1 - 4.5e-34 117.8 0.0 6.6e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EKE42989.1 - 3e-07 30.9 0.0 1.5e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain PELOTA_1 PF15608.1 EKE42990.1 - 0.44 10.3 2.5 0.61 9.8 0.6 1.9 1 1 1 2 2 2 0 PELOTA RNA binding domain eIF-3c_N PF05470.7 EKE42991.1 - 2.6e-13 48.9 0.1 2.6e-13 48.9 0.1 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Daxx PF03344.10 EKE42991.1 - 0.19 10.1 25.4 0.26 9.7 17.6 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EKE42991.1 - 0.83 8.3 29.4 1.2 7.7 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EKE42991.1 - 2.7 5.9 15.3 1.5 6.7 9.1 1.8 2 0 0 2 2 2 0 CDC45-like protein ThiF PF00899.16 EKE42992.1 - 1.2e-26 93.1 0.0 2.9e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EKE42992.1 - 0.013 15.5 0.0 0.052 13.6 0.0 2.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ERM PF00769.14 EKE42993.1 - 0.0018 17.8 9.4 0.0018 17.8 6.5 1.5 2 0 0 2 2 2 1 Ezrin/radixin/moesin family DUF2077 PF09850.4 EKE42993.1 - 0.023 14.1 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF4064 PF13273.1 EKE42993.1 - 0.039 14.0 3.7 0.083 13.0 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Pox_A9 PF04835.7 EKE42993.1 - 0.14 12.1 2.5 0.26 11.2 1.7 1.4 1 0 0 1 1 1 0 A9 protein conserved region DUF3753 PF12575.3 EKE42993.1 - 0.4 10.5 6.3 0.6 9.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) BSMAP PF12280.3 EKE42993.1 - 1.6 8.5 4.6 0.5 10.2 0.9 1.7 2 0 0 2 2 2 0 Brain specific membrane anchored protein OmpH PF03938.9 EKE42993.1 - 2 8.3 18.4 1.2 9.0 4.0 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Pex24p PF06398.6 EKE42993.1 - 2.4 6.8 8.0 0.55 8.9 3.3 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin MCC-bdg_PDZ PF10506.4 EKE42994.1 - 0.62 9.9 3.6 4.9 7.0 0.9 2.5 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome EmrE PF13536.1 EKE42996.1 - 7.5e-06 26.1 3.3 7.5e-06 26.1 2.3 3.2 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EKE42996.1 - 4e-05 23.6 9.2 4e-05 23.6 6.4 4.5 2 2 0 3 3 3 1 EamA-like transporter family COX4_pro_2 PF07835.7 EKE42996.1 - 0.0029 17.5 0.6 0.0029 17.5 0.4 2.6 3 0 0 3 3 3 1 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2574 PF10836.3 EKE42997.1 - 1.2 8.8 3.5 30 4.4 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2574) Peptidase_C1 PF00112.18 EKE42998.1 - 1.2e-07 31.8 0.4 3.7e-05 23.6 0.0 2.6 2 1 0 2 2 2 2 Papain family cysteine protease DNA_topoisoIV PF00521.15 EKE42999.1 - 0.056 12.2 0.6 0.058 12.2 0.4 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Toxin_56 PF15534.1 EKE42999.1 - 0.096 13.1 0.1 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 56 Myb_DNA-bind_4 PF13837.1 EKE42999.1 - 0.15 12.2 1.7 0.25 11.4 1.2 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain CASP_C PF08172.7 EKE42999.1 - 0.55 9.2 5.3 2 7.3 0.9 2.0 2 0 0 2 2 2 0 CASP C terminal ECM11 PF15463.1 EKE42999.1 - 0.9 9.8 3.7 1.5 9.0 0.6 2.0 2 0 0 2 2 2 0 Extracellular mutant protein 11 Ribul_P_3_epim PF00834.14 EKE43000.1 - 5.3e-71 237.8 1.7 6.2e-71 237.6 1.2 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EKE43000.1 - 0.00021 20.8 1.2 0.00098 18.6 0.3 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EKE43000.1 - 0.00045 19.5 0.7 0.049 12.8 0.0 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein Mem_trans PF03547.13 EKE43001.1 - 1.4e-09 36.7 1.7 2.3e-09 36.0 1.2 1.2 1 0 0 1 1 1 1 Membrane transport protein Pkinase_Tyr PF07714.12 EKE43004.1 - 1.4e-55 188.1 0.1 3.2e-55 187.0 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKE43004.1 - 2.1e-54 184.4 0.7 2.1e-54 184.4 0.5 2.1 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EKE43004.1 - 9.8e-05 21.5 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKE43004.1 - 0.0025 16.8 0.2 0.02 13.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DOCK-C2 PF14429.1 EKE43005.1 - 2.3e-44 151.2 3.8 7.7e-44 149.5 2.7 2.0 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EKE43005.1 - 4.4e-35 120.5 2.1 6.6e-35 119.9 0.1 2.4 2 0 0 2 2 2 1 Dedicator of cytokinesis DUF948 PF06103.6 EKE43005.1 - 0.51 10.2 6.0 2 8.3 0.2 4.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PGM_PMM_I PF02878.11 EKE43006.1 - 1.5e-40 137.8 0.0 4.7e-40 136.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EKE43006.1 - 6.5e-23 81.0 0.0 1.4e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EKE43006.1 - 4.7e-11 42.7 0.4 1.1e-10 41.5 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EKE43006.1 - 6.1e-07 29.3 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ran_BP1 PF00638.13 EKE43007.1 - 4.3e-24 84.9 0.2 5.2e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 RanBP1 domain HD_4 PF13328.1 EKE43008.1 - 2.7e-25 88.8 0.0 3.2e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 EKE43008.1 - 3e-05 24.0 0.5 5.2e-05 23.2 0.3 1.4 1 1 0 1 1 1 1 HD domain RNA_pol_Rpb2_2 PF04561.9 EKE43008.1 - 0.021 14.2 0.2 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Cadherin_pro PF08758.6 EKE43008.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Cadherin prodomain like DUF1993 PF09351.5 EKE43008.1 - 0.059 13.3 0.2 0.086 12.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) DUF4375 PF14300.1 EKE43008.1 - 0.09 12.7 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Radical_SAM PF04055.16 EKE43008.1 - 0.14 12.2 0.3 2.1 8.5 0.0 2.0 1 1 1 2 2 2 0 Radical SAM superfamily KNOX2 PF03791.8 EKE43009.1 - 0.049 12.9 0.1 0.14 11.4 0.1 1.7 2 0 0 2 2 2 0 KNOX2 domain DUF4363 PF14276.1 EKE43010.1 - 0.012 15.3 0.4 0.012 15.3 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) DUF2392 PF10288.4 EKE43010.1 - 0.12 12.6 7.7 0.24 11.7 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2392) BLOC1_2 PF10046.4 EKE43010.1 - 0.44 10.7 13.2 0.27 11.4 1.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LUC7 PF03194.10 EKE43010.1 - 0.65 9.4 8.3 6.1 6.2 5.8 2.0 1 1 0 1 1 1 0 LUC7 N_terminus Ada3 PF10198.4 EKE43010.1 - 8.7 6.1 9.7 7 6.4 0.5 2.4 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 VPS9 PF02204.13 EKE43011.1 - 8.3e-21 73.9 0.1 2e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Cys_rich_KTR PF14205.1 EKE43011.1 - 0.034 13.5 0.3 0.1 12.0 0.2 1.8 1 0 0 1 1 1 0 Cysteine-rich KTR Cytomega_TRL10 PF06084.6 EKE43012.1 - 0.49 10.1 1.5 1.3 8.7 0.1 2.0 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Vma12 PF11712.3 EKE43012.1 - 1.3 8.7 7.3 0.43 10.2 0.3 2.5 2 1 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PCI PF01399.22 EKE43014.1 - 1.2e-16 60.8 4.8 2.2e-16 60.0 1.9 2.4 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EKE43014.1 - 7.8e-05 22.4 2.7 7.8e-05 22.4 1.9 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Flexi_CP PF00286.15 EKE43014.1 - 0.061 13.0 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Viral coat protein ATP_bind_4 PF01902.12 EKE43015.1 - 7.8e-41 139.8 0.1 4.1e-40 137.4 0.1 1.8 1 1 0 1 1 1 1 ATP-binding region QueC PF06508.8 EKE43015.1 - 0.0089 15.3 0.1 0.24 10.6 0.1 2.3 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EKE43015.1 - 0.024 14.1 0.0 0.095 12.1 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EKE43015.1 - 0.044 12.3 0.0 0.071 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase NYN PF01936.13 EKE43015.1 - 0.11 12.7 0.0 13 6.1 0.0 2.2 2 0 0 2 2 2 0 NYN domain Peptidase_S74 PF13884.1 EKE43016.1 - 7.1e-15 54.8 0.0 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase CR6_interact PF10147.4 EKE43016.1 - 0.00077 18.8 0.9 0.00077 18.8 0.6 1.8 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Mitofilin PF09731.4 EKE43016.1 - 0.0026 16.5 1.2 0.0046 15.6 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial inner membrane protein GldM_N PF12081.3 EKE43016.1 - 0.0087 15.5 1.2 0.024 14.1 0.8 1.7 1 0 0 1 1 1 1 GldM N-terminal domain HalX PF08663.5 EKE43016.1 - 0.21 11.5 2.3 0.41 10.6 1.6 1.4 1 0 0 1 1 1 0 HalX domain DUF4337 PF14235.1 EKE43016.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Pico_P2B PF01552.12 EKE43017.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.9 3 1 2 5 5 5 0 Picornavirus 2B protein SpoU_methylase PF00588.14 EKE43018.1 - 2.9e-26 92.0 0.1 5e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family RRM_1 PF00076.17 EKE43018.1 - 2.2e-14 52.8 0.3 4.6e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKE43018.1 - 4.7e-11 42.4 0.1 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKE43018.1 - 1.3e-07 31.3 0.1 5.6e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltrn_RNA_4 PF09936.4 EKE43018.1 - 0.00013 21.5 0.0 0.0023 17.4 0.0 2.4 1 1 0 1 1 1 1 SAM-dependent RNA methyltransferase RRM_3 PF08777.6 EKE43018.1 - 0.00072 19.3 0.2 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EKE43018.1 - 0.011 15.4 0.1 0.034 13.9 0.1 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HTH_40 PF14493.1 EKE43018.1 - 0.08 13.1 0.2 0.25 11.5 0.1 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_6 PF12697.2 EKE43019.1 - 1.3e-07 31.7 0.0 1.8e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKE43019.1 - 0.0015 18.2 0.0 0.0024 17.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EKE43019.1 - 0.0031 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EKE43019.1 - 0.0058 16.2 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EKE43019.1 - 0.089 11.8 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Thioredoxin PF00085.15 EKE43020.1 - 4.9e-12 45.4 0.0 6.7e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKE43020.1 - 0.0055 16.8 0.2 0.0082 16.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EKE43020.1 - 0.027 14.4 0.1 0.065 13.2 0.1 1.5 1 1 1 2 2 2 0 Thioredoxin DIM1 PF02966.11 EKE43020.1 - 0.057 12.9 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 DNA_pol_B PF00136.16 EKE43021.1 - 9.2e-139 463.1 3.5 1.9e-138 462.1 2.4 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EKE43021.1 - 2.4e-69 233.6 5.0 2.4e-69 233.6 3.5 2.4 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EKE43021.1 - 2.6e-18 65.7 11.2 2.6e-18 65.7 7.8 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Cript PF10235.4 EKE43021.1 - 3.3 8.1 10.3 13 6.2 0.8 2.6 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Prok-RING_1 PF14446.1 EKE43021.1 - 4 7.2 12.8 6.6 6.5 1.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HTH_10 PF04967.7 EKE43022.1 - 0.0045 16.5 0.6 0.34 10.5 0.1 3.1 3 0 0 3 3 3 1 HTH DNA binding domain TF_Zn_Ribbon PF08271.7 EKE43022.1 - 0.04 13.2 2.6 0.14 11.4 1.8 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding NMT_C PF02799.10 EKE43022.1 - 0.073 12.4 0.9 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DZR PF12773.2 EKE43022.1 - 0.078 12.8 0.4 0.19 11.5 0.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EKE43022.1 - 1.5 8.1 4.1 8.9 5.6 3.0 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Wbp11 PF09429.5 EKE43022.1 - 4.2 7.4 10.3 2.4 8.2 0.2 3.9 3 0 0 3 3 3 0 WW domain binding protein 11 PP2C_C PF07830.8 EKE43022.1 - 4.7 7.3 6.3 4.4 7.4 0.2 3.5 4 0 0 4 4 4 0 Protein serine/threonine phosphatase 2C, C-terminal domain NPR2 PF06218.6 EKE43023.1 - 2e-51 175.0 4.2 9.7e-51 172.8 2.9 1.8 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EKE43023.1 - 4.1e-05 22.3 0.0 0.0019 16.8 0.0 2.2 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Pox_TAA1 PF03295.9 EKE43023.1 - 0.072 12.7 0.7 8.2 6.1 0.2 2.7 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal Latarcin PF10279.4 EKE43024.1 - 0.089 12.9 1.1 0.12 12.5 0.8 1.4 1 1 0 1 1 1 0 Latarcin precursor Noc2 PF03715.8 EKE43024.1 - 0.27 10.0 2.2 2.1 7.0 0.0 2.0 2 0 0 2 2 2 0 Noc2p family FH2 PF02181.18 EKE43025.1 - 8.6e-58 195.9 12.3 8.6e-58 195.9 8.5 3.2 2 1 1 3 3 3 1 Formin Homology 2 Domain TSC22 PF01166.13 EKE43025.1 - 0.0014 18.5 0.5 0.0014 18.5 0.3 5.0 6 0 0 6 6 6 1 TSC-22/dip/bun family DUF3361 PF11841.3 EKE43025.1 - 0.0021 17.8 1.2 0.0021 17.8 0.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF869 PF05911.6 EKE43025.1 - 0.0096 14.2 26.4 0.15 10.2 11.8 3.0 3 0 0 3 3 3 2 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EKE43025.1 - 0.058 12.5 5.1 0.39 9.8 0.4 2.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF605 PF04652.11 EKE43025.1 - 0.67 9.2 17.2 1.2 8.4 11.9 1.5 1 0 0 1 1 1 0 Vta1 like HALZ PF02183.13 EKE43025.1 - 1.5 8.6 13.5 1.1 9.0 1.0 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper UPF0114 PF03350.11 EKE43025.1 - 1.9 8.4 4.0 8.1 6.3 1.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 Nup54 PF13874.1 EKE43025.1 - 3.5 7.2 12.2 0.22 11.1 1.9 3.4 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Alpha_kinase PF02816.13 EKE43026.1 - 3e-39 134.6 2.9 4.3e-39 134.1 2.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family SH3_1 PF00018.23 EKE43026.1 - 2.5e-16 58.7 0.7 1.1e-11 43.9 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EKE43026.1 - 8.9e-16 57.1 1.4 1.9e-09 36.8 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 EKE43026.1 - 2.8e-15 55.6 0.1 1.2e-09 37.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Na_H_Exchanger PF00999.16 EKE43027.1 - 5.1e-53 179.9 43.4 6.5e-53 179.6 30.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrbC PF04956.8 EKE43027.1 - 2.9 7.9 12.1 0.028 14.4 1.7 2.8 2 2 0 2 2 2 0 TrbC/VIRB2 family EF-hand_1 PF00036.27 EKE43029.1 - 3.5e-12 44.6 0.0 0.0054 15.9 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EKE43029.1 - 6.2e-09 35.8 0.0 3.2e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKE43029.1 - 1.9e-08 33.4 0.0 0.14 12.0 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EKE43029.1 - 9.2e-07 27.9 0.0 0.075 12.4 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EKE43029.1 - 0.00022 20.7 0.1 0.0041 16.7 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_10 PF14788.1 EKE43029.1 - 0.11 12.2 0.0 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 EF hand TLD PF07534.11 EKE43030.1 - 0.0021 18.0 1.3 0.0048 16.8 0.1 2.2 2 2 0 2 2 2 1 TLD FlxA PF14282.1 EKE43030.1 - 0.21 11.5 5.3 1.4 8.8 0.4 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF1548 PF07579.6 EKE43030.1 - 0.73 9.9 4.8 0.28 11.3 1.4 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) Syntaxin-6_N PF09177.6 EKE43030.1 - 0.98 9.8 4.6 1.7 9.1 3.2 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Peptidase_C1 PF00112.18 EKE43031.1 - 1.7e-56 191.5 2.7 2.7e-56 190.8 1.8 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EKE43031.1 - 8.1e-07 29.2 0.2 1.9e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EKE43031.1 - 0.0097 14.4 0.0 0.097 11.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Cofilin_ADF PF00241.15 EKE43032.1 - 1.3e-37 128.5 0.6 1.4e-37 128.3 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ELL PF10390.4 EKE43033.1 - 0.021 14.0 4.4 0.026 13.7 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Rap1_C PF11626.3 EKE43033.1 - 0.062 13.1 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sec20 PF03908.8 EKE43033.1 - 0.41 10.3 2.5 3.5 7.3 0.0 3.0 2 1 0 3 3 3 0 Sec20 Rhomboid PF01694.17 EKE43034.1 - 3e-33 114.8 14.6 3e-33 114.8 10.1 1.9 3 0 0 3 3 3 1 Rhomboid family DUF1751 PF08551.5 EKE43034.1 - 0.0028 17.9 0.3 0.0028 17.9 0.2 2.1 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF4203 PF13886.1 EKE43034.1 - 1.7 8.0 27.4 0.038 13.4 6.6 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4203) PIG-S PF10510.4 EKE43035.1 - 0.042 12.5 12.6 0.0069 15.1 5.9 1.5 1 1 1 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein Surface_Ag_2 PF01617.12 EKE43035.1 - 1.4 8.0 6.6 1.9 7.6 0.8 2.1 2 0 0 2 2 2 0 Surface antigen PI3_PI4_kinase PF00454.22 EKE43037.1 - 8e-31 107.3 0.4 9.8e-31 107.0 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EKE43037.1 - 3.4e-08 32.7 0.0 6.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 FATC domain UCH PF00443.24 EKE43038.1 - 2.3e-32 112.1 2.8 4.3e-32 111.2 1.9 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKE43038.1 - 2.6e-17 63.1 1.7 4.8e-17 62.3 1.2 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SGL PF08450.7 EKE43039.1 - 0.09 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region CTP_transf_1 PF01148.15 EKE43040.1 - 1.4e-07 31.4 30.2 3.2e-06 26.9 20.9 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family DUF962 PF06127.6 EKE43040.1 - 0.0046 16.8 0.5 0.91 9.4 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF962) Rotamase_3 PF13616.1 EKE43041.1 - 4.5e-22 78.5 0.1 6.1e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EKE43041.1 - 8e-22 77.7 0.1 1.6e-21 76.7 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EKE43041.1 - 4.3e-09 37.0 0.1 7.4e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain DNA_alkylation PF08713.6 EKE43042.1 - 1.9e-25 89.6 0.0 2.4e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme UPF0184 PF03670.8 EKE43044.1 - 0.017 15.2 1.2 0.017 15.2 0.9 3.0 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) RhoGAP PF00620.22 EKE43045.1 - 0.00015 21.3 0.2 0.00037 20.1 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EKE43045.1 - 0.0069 16.5 1.6 0.01 16.0 0.4 1.8 2 0 0 2 2 2 1 PH domain zf-HIT PF04438.11 EKE43048.1 - 9.4e-05 21.9 8.6 0.00017 21.1 6.0 1.5 1 0 0 1 1 1 1 HIT zinc finger Gemini_AL1_M PF08283.6 EKE43048.1 - 0.0099 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Geminivirus rep protein central domain Cnd1 PF12717.2 EKE43049.1 - 0.0069 16.2 3.6 0.0069 16.2 2.5 2.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EKE43049.1 - 0.027 14.3 4.4 4.8 7.1 0.0 5.7 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 EKE43050.1 - 6.2e-68 228.7 0.0 7.7e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKE43050.1 - 2.5e-31 108.6 0.0 7.3e-31 107.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKE43050.1 - 0.00011 21.2 1.1 0.0012 17.9 0.1 2.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EKE43050.1 - 0.027 14.1 0.0 0.1 12.3 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.1 EKE43051.1 - 9e-08 31.6 7.0 2.4e-07 30.3 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKE43051.1 - 1.9e-07 30.8 12.3 2.7e-07 30.3 4.5 3.0 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EKE43051.1 - 1.9e-07 30.9 10.6 1.9e-07 30.9 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKE43051.1 - 6e-07 29.0 9.7 2.1e-06 27.2 6.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKE43051.1 - 4.5e-06 26.3 9.0 1.6e-05 24.6 6.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKE43051.1 - 2.4e-05 23.9 10.8 6.5e-05 22.5 7.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EKE43051.1 - 0.0002 20.8 5.1 0.00069 19.1 3.6 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain F-box-like PF12937.2 EKE43051.1 - 0.034 13.8 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like zf-rbx1 PF12678.2 EKE43051.1 - 0.11 12.6 9.8 0.043 13.9 4.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger zf-P11 PF03854.9 EKE43051.1 - 0.15 11.5 5.0 0.49 9.9 3.5 1.9 1 1 0 1 1 1 0 P-11 zinc finger TPR_12 PF13424.1 EKE43052.1 - 8.7e-10 38.4 0.4 0.6 10.0 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKE43052.1 - 2.6e-09 36.5 9.1 0.0071 15.9 0.0 5.1 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 EKE43052.1 - 2.7e-07 29.9 13.0 0.79 9.7 0.2 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EKE43052.1 - 7.4e-05 22.9 5.5 0.028 14.8 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat HHH_8 PF14716.1 EKE43052.1 - 0.015 15.4 1.8 1.2 9.3 0.0 4.4 4 0 0 4 4 4 0 Helix-hairpin-helix domain TPR_19 PF14559.1 EKE43052.1 - 0.016 15.5 0.0 5.3 7.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKE43052.1 - 0.023 14.2 21.8 5.9 6.6 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKE43052.1 - 0.12 12.1 34.4 0.047 13.4 1.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKE43052.1 - 0.15 12.8 0.0 1.2e+02 3.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HEPN PF05168.9 EKE43053.1 - 0.009 15.8 2.3 0.017 14.9 0.5 2.1 2 0 0 2 2 2 1 HEPN domain TPR_19 PF14559.1 EKE43053.1 - 0.0097 16.2 0.1 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EKE43053.1 - 0.031 14.3 2.1 0.1 12.7 0.9 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Prefoldin PF02996.12 EKE43053.1 - 0.87 9.2 6.9 7.7 6.2 0.2 2.9 2 1 1 3 3 3 0 Prefoldin subunit PPR_2 PF13041.1 EKE43053.1 - 3.2 7.7 5.7 13 5.8 0.2 3.7 3 1 1 4 4 4 0 PPR repeat family RabGAP-TBC PF00566.13 EKE43054.1 - 2.6e-35 121.8 4.5 4.5e-35 121.0 3.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4175 PF13779.1 EKE43054.1 - 0.13 9.8 0.8 0.18 9.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175)