# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Peptidase_M24 PF00557.19 EMR72941.1 - 4.8e-31 107.9 0.3 7e-31 107.4 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMR72941.1 - 1.6e-14 54.5 0.0 2.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain AAA PF00004.24 EMR72942.1 - 7.2e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.13 EMR72942.1 - 2.3e-09 37.0 0.6 5.7e-09 35.7 0.4 1.6 1 1 0 1 1 1 1 Peptidase family M41 DUF1724 PF08350.5 EMR72942.1 - 0.019 14.4 0.6 0.075 12.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) GlcNAc_2-epim PF07221.6 EMR72942.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1616 PF07760.6 EMR72943.1 - 1.4e-09 37.4 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) DUF4398 PF14346.1 EMR72944.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) SRR1 PF07985.7 EMR72945.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 SRR1 DUF1098 PF06497.6 EMR72945.1 - 0.17 11.9 1.2 0.28 11.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) MAD PF05557.8 EMR72946.1 - 0.00056 18.1 26.9 0.0034 15.5 18.6 1.9 1 1 0 1 1 1 1 Mitotic checkpoint protein CCDC155 PF14662.1 EMR72946.1 - 0.012 15.2 17.1 0.02 14.4 1.9 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Malic_M PF03949.10 EMR72946.1 - 0.018 14.5 0.5 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain TSC22 PF01166.13 EMR72946.1 - 0.042 13.8 1.0 0.042 13.8 0.7 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family Uds1 PF15456.1 EMR72946.1 - 0.13 12.2 12.9 0.23 11.4 0.7 2.6 2 1 0 2 2 2 0 Up-regulated During Septation Pox_TAA1 PF03295.9 EMR72946.1 - 0.17 11.5 3.1 5.6 6.7 0.5 2.6 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal WEMBL PF05701.6 EMR72946.1 - 0.32 9.4 24.1 0.53 8.6 16.7 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light IncA PF04156.9 EMR72946.1 - 0.35 10.4 22.4 0.044 13.3 3.1 2.5 3 0 0 3 3 3 0 IncA protein DUF3372 PF11852.3 EMR72946.1 - 0.35 9.9 4.1 5.2 6.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3372) Seryl_tRNA_N PF02403.17 EMR72946.1 - 0.37 10.8 24.2 0.7 9.9 6.6 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Sec8_exocyst PF04048.9 EMR72946.1 - 0.4 10.2 19.7 1.4 8.5 3.4 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain APG6 PF04111.7 EMR72946.1 - 0.82 8.6 24.6 1.7 7.6 5.7 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 ZapA PF05164.8 EMR72946.1 - 1.1 9.3 10.0 0.11 12.4 0.5 3.0 3 0 0 3 3 3 0 Cell division protein ZapA DUF4140 PF13600.1 EMR72946.1 - 1.2 9.6 12.7 0.23 11.9 0.6 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) UBN2_3 PF14244.1 EMR72946.1 - 1.6 8.2 10.8 3.1 7.3 0.2 3.1 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type DUF3450 PF11932.3 EMR72946.1 - 1.7 7.8 17.0 4.6 6.4 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 EMR72946.1 - 1.7 8.4 19.8 0.36 10.6 4.7 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) UDPG_MGDP_dh_C PF03720.10 EMR72946.1 - 1.8 8.7 4.7 1.5e+02 2.5 3.2 2.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AMP-binding_C_2 PF14535.1 EMR72946.1 - 2.1 8.4 7.7 0.27 11.3 0.9 2.5 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain Mnd1 PF03962.10 EMR72946.1 - 2.9 7.4 17.7 1.1 8.9 2.0 2.3 2 0 0 2 2 2 0 Mnd1 family DivIC PF04977.10 EMR72946.1 - 3.5 7.1 23.2 1.2 8.7 2.9 3.6 2 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.6 EMR72946.1 - 6.2 5.3 27.9 0.67 8.5 4.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 EMR72946.1 - 6.7 6.5 28.8 4.9 6.9 0.7 3.7 3 1 0 3 3 3 0 Prefoldin subunit TBPIP PF07106.8 EMR72946.1 - 7.6 6.0 33.7 0.84 9.1 5.2 3.8 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 EMR72946.1 - 7.7 6.1 21.0 3.3 7.3 0.9 4.1 3 1 1 4 4 4 0 Prefoldin subunit DUF2730 PF10805.3 EMR72946.1 - 7.9 6.2 12.5 0.84 9.4 0.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) FliD_N PF02465.13 EMR72946.1 - 8.4 6.8 11.9 17 5.8 0.2 3.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CDC37_N PF03234.9 EMR72946.1 - 8.7 6.6 19.5 6.7 6.9 5.7 2.4 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding Glycos_transf_1 PF00534.15 EMR72980.1 - 3.2e-31 108.0 0.0 4.1e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR72980.1 - 1.8e-18 66.9 0.0 3.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 EMR72980.1 - 1.2e-11 44.6 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_2 PF13524.1 EMR72980.1 - 3.1e-10 40.1 0.0 5.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMR72980.1 - 0.00073 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 AFOR_C PF01314.13 EMR72983.1 - 1e-19 70.4 0.1 1.1e-19 70.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Methyltransf_11 PF08241.7 EMR72987.1 - 6.1e-20 71.5 0.0 9e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72987.1 - 2.3e-17 62.9 0.0 2.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR72987.1 - 3.2e-14 52.9 0.0 4e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR72987.1 - 3.3e-13 49.8 0.0 4.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR72987.1 - 2.3e-12 47.2 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72987.1 - 2.3e-07 31.3 0.0 3.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR72987.1 - 2e-06 27.0 0.0 2.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EMR72987.1 - 2.4e-06 27.0 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EMR72987.1 - 3.9e-05 23.6 0.0 0.0001 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMR72987.1 - 0.00092 18.0 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.11 EMR72987.1 - 0.0056 15.0 0.0 0.0074 14.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 EMR72987.1 - 0.0073 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 EMR72987.1 - 0.0081 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.7 EMR72987.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_8 PF05148.10 EMR72987.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.15 EMR72987.1 - 0.022 13.8 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADP_ribosyl_GH PF03747.9 EMR73006.1 - 1.6e-68 231.6 0.0 1.8e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Lactamase_B_2 PF12706.2 EMR73008.1 - 2.9e-16 59.6 0.1 1.6e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain RMMBL PF07521.7 EMR73008.1 - 2.1e-10 40.2 0.8 6.6e-10 38.6 0.6 1.9 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EMR73008.1 - 5.9e-10 39.1 4.8 2.7e-09 36.9 3.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EMR73008.1 - 2.6e-07 30.5 0.0 5.1e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Flavodoxin_3 PF12641.2 EMR73008.1 - 0.13 11.6 0.0 0.61 9.5 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain DUF262 PF03235.9 EMR73009.1 - 1.6e-26 93.6 1.4 1.6e-26 93.6 1.0 3.2 3 1 0 3 3 3 1 Protein of unknown function DUF262 Sec23_helical PF04815.10 EMR73009.1 - 0.056 12.8 0.3 0.47 9.9 0.1 2.5 2 0 0 2 2 2 0 Sec23/Sec24 helical domain DUF234 PF03008.9 EMR73010.1 - 0.023 14.8 0.8 0.048 13.7 0.6 1.5 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function DUF4083 PF13314.1 EMR73013.1 - 0.15 11.9 0.2 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Ribonucleas_3_3 PF14622.1 EMR73014.1 - 9.9e-28 96.6 0.7 1.5e-27 96.0 0.5 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMR73014.1 - 1.6e-19 70.4 0.0 4e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EMR73014.1 - 3.1e-13 50.0 0.2 7.4e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Lon_2 PF13337.1 EMR73015.1 - 1.8e-98 329.8 0.0 2.5e-98 329.4 0.0 1.2 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease Lon_C PF05362.8 EMR73015.1 - 4.9e-16 58.6 0.0 8.9e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 EMR73015.1 - 0.00073 19.0 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Abi_2 PF07751.6 EMR73015.1 - 0.0032 17.6 5.4 0.0063 16.7 3.7 1.5 1 0 0 1 1 1 1 Abi-like protein PA28_beta PF02252.13 EMR73015.1 - 0.12 11.8 1.1 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit Peptidase_M50 PF02163.17 EMR73018.1 - 5.6e-13 48.2 9.1 7.3e-13 47.8 6.3 1.3 1 1 0 1 1 1 1 Peptidase family M50 ABC2_membrane_5 PF13346.1 EMR73018.1 - 0.12 11.6 9.6 0.15 11.3 6.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4234 PF14018.1 EMR73018.1 - 2.3 8.0 6.8 8.2 6.2 4.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) 2TM PF13239.1 EMR73018.1 - 9.4 6.3 7.4 8.8 6.4 4.7 1.4 1 1 0 1 1 1 0 2TM domain Peptidase_M50 PF02163.17 EMR73019.1 - 0.94 8.3 3.5 0.76 8.7 1.1 1.8 1 1 1 2 2 2 0 Peptidase family M50 TraB PF01963.12 EMR73020.1 - 3.7e-54 183.9 0.7 4.9e-54 183.4 0.5 1.1 1 0 0 1 1 1 1 TraB family RB_A PF01858.12 EMR73020.1 - 0.043 13.4 0.1 0.088 12.4 0.1 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain TOBE PF03459.12 EMR73020.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 TOBE domain Response_reg PF00072.19 EMR73024.1 - 0.00035 20.5 0.0 0.00045 20.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.6 EMR73024.1 - 0.073 13.2 0.1 0.095 12.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Glycos_transf_2 PF00535.21 EMR73025.1 - 1e-22 80.6 0.1 1.2e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR73025.1 - 4.8e-10 39.6 0.0 5.4e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EMR73025.1 - 0.0001 22.5 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMR73025.1 - 0.0098 15.1 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Dioxygenase_N PF04444.9 EMR73031.1 - 0.064 13.2 0.3 2.4 8.2 0.0 2.9 2 2 1 3 3 3 0 Catechol dioxygenase N terminus Amidohydro_5 PF13594.1 EMR73034.1 - 7.8e-15 54.4 3.3 1e-14 54.0 0.4 2.5 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR73034.1 - 2.7e-14 53.2 0.0 4.2e-14 52.5 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR73034.1 - 8.9e-09 35.7 0.0 3.5e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR73034.1 - 0.00012 21.8 0.0 0.00038 20.2 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EMR73034.1 - 0.084 13.0 0.7 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain P5CR_dimer PF14748.1 EMR73035.1 - 6.1e-35 119.4 0.3 1e-34 118.7 0.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMR73035.1 - 3.6e-18 65.7 1.2 6e-18 65.0 0.8 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMR73035.1 - 2.3e-06 27.5 0.1 4e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EMR73035.1 - 1.9e-05 24.1 1.1 9e-05 21.9 0.2 2.4 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EMR73035.1 - 9.7e-05 21.5 0.4 0.00016 20.8 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR73035.1 - 0.00025 20.8 0.4 0.0048 16.6 0.3 2.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.19 EMR73035.1 - 0.00032 20.9 0.2 0.00069 19.9 0.2 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EMR73035.1 - 0.022 14.9 0.1 0.054 13.6 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain Shikimate_DH PF01488.15 EMR73035.1 - 0.023 14.8 0.4 0.043 13.9 0.3 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMR73035.1 - 0.031 14.2 2.0 0.035 14.1 0.4 1.8 2 0 0 2 2 2 0 TrkA-N domain PDH PF02153.12 EMR73035.1 - 0.032 13.1 0.7 0.05 12.4 0.2 1.5 2 0 0 2 2 2 0 Prephenate dehydrogenase adh_short PF00106.20 EMR73035.1 - 0.049 13.5 0.6 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Saccharop_dh PF03435.13 EMR73035.1 - 0.056 12.4 0.5 0.075 12.0 0.3 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMR73035.1 - 0.14 11.5 2.9 3.2 7.1 0.0 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GMP_synt_C PF00958.17 EMR73036.1 - 2.7e-24 84.7 1.2 1.2e-20 72.9 0.8 2.8 1 1 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EMR73036.1 - 2.6e-10 39.6 0.0 3.9e-09 35.7 0.0 2.4 1 1 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.15 EMR73036.1 - 3.7e-07 29.8 0.0 5.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 EMR73036.1 - 0.00086 17.9 0.0 0.0063 15.1 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 EMR73036.1 - 0.042 13.3 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Asparagine synthase ThiI PF02568.9 EMR73036.1 - 0.044 13.2 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NUDIX PF00293.23 EMR73041.1 - 4.9e-18 65.0 0.0 6e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EMR73041.1 - 1.4e-09 37.3 0.0 1.6e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 EMR73041.1 - 0.0079 15.5 0.3 0.013 14.8 0.0 1.6 2 1 0 2 2 2 1 Nucleotide hydrolase zf-NADH-PPase PF09297.6 EMR73042.1 - 0.00035 20.0 0.1 0.00071 19.0 0.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.2 EMR73042.1 - 0.0084 15.9 0.4 0.026 14.3 0.3 1.5 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EMR73042.1 - 0.0093 15.1 0.6 0.02 14.1 0.4 1.5 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMR73042.1 - 0.021 14.2 3.4 0.56 9.7 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF1451 PF07295.6 EMR73042.1 - 0.057 13.2 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) A2L_zn_ribbon PF08792.5 EMR73042.1 - 0.068 12.6 1.3 3.1 7.3 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Nudix_N_2 PF14803.1 EMR73042.1 - 0.069 12.8 1.6 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_6 PF14599.1 EMR73042.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon DNA_RNApol_7kD PF03604.8 EMR73042.1 - 0.1 12.0 1.6 0.19 11.2 1.1 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EMR73042.1 - 0.11 12.1 0.2 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family HpcH_HpaI PF03328.9 EMR73043.1 - 1.8e-45 154.5 0.0 2.1e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Methyltransf_3 PF01596.12 EMR73045.1 - 4.2e-22 78.1 0.0 5.3e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMR73045.1 - 2.9e-15 56.9 0.0 4.4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR73045.1 - 3.6e-11 43.6 0.0 5.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73045.1 - 2.2e-08 33.8 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR73045.1 - 8.6e-06 25.4 0.1 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EMR73045.1 - 1.3e-05 24.9 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein CmcI PF04989.7 EMR73045.1 - 2.1e-05 23.9 0.4 3.5e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 EMR73045.1 - 3.1e-05 23.9 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 EMR73045.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EMR73045.1 - 0.0053 16.1 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMR73045.1 - 0.012 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EMR73045.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.13 EMR73045.1 - 0.035 13.2 0.1 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EMR73045.1 - 0.066 12.2 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 EMR73045.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Bac_luciferase PF00296.15 EMR73046.1 - 2.7e-50 171.2 0.0 3.5e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase VirE_N PF08800.5 EMR73046.1 - 0.13 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 VirE N-terminal domain GCD14 PF08704.5 EMR73048.1 - 2.4e-40 138.5 0.0 1.1e-39 136.3 0.0 1.7 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EMR73048.1 - 2.8e-11 43.9 0.0 4.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73048.1 - 6.7e-10 38.7 0.0 8.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR73048.1 - 5.8e-09 35.7 0.0 7.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EMR73048.1 - 1.3e-08 34.9 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EMR73048.1 - 2.4e-06 26.7 0.0 5.8e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase RrnaAD PF00398.15 EMR73048.1 - 2.2e-05 23.5 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EMR73048.1 - 2.7e-05 24.9 0.0 5.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.8 EMR73048.1 - 2.8e-05 23.3 0.1 0.00039 19.6 0.0 2.0 1 1 1 2 2 2 1 Gcd10p family MTS PF05175.9 EMR73048.1 - 5.6e-05 22.5 0.0 9.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMR73048.1 - 0.00013 21.1 0.0 0.00038 19.6 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EMR73048.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EMR73048.1 - 0.0034 17.8 0.0 0.0067 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR73048.1 - 0.0078 15.3 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EMR73048.1 - 0.013 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EMR73048.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR73048.1 - 0.016 15.5 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EMR73048.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein VP9 PF09625.5 EMR73048.1 - 0.021 14.5 0.3 0.077 12.8 0.1 2.0 2 1 0 2 2 2 0 VP9 protein CMAS PF02353.15 EMR73048.1 - 0.026 13.6 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EMR73048.1 - 0.051 13.0 0.2 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EMR73048.1 - 0.063 13.2 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EMR73048.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M42 PF05343.9 EMR73049.1 - 1.2e-96 322.9 0.0 1.4e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 EMR73049.1 - 6.3e-12 45.3 0.1 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M18 PF02127.10 EMR73049.1 - 0.0001 21.0 0.0 0.0084 14.6 0.0 2.2 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M28 PF04389.12 EMR73049.1 - 0.00025 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF2642 PF10842.3 EMR73049.1 - 0.0031 16.9 0.1 0.008 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2642) MethyltransfD12 PF02086.10 EMR73050.1 - 5.6e-67 225.9 0.0 6.3e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 EMR73050.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain SNARE_assoc PF09335.6 EMR73051.1 - 2.5e-16 60.0 3.5 2.5e-16 60.0 2.4 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein Sm_multidrug_ex PF06695.6 EMR73051.1 - 0.033 14.3 4.4 0.38 10.9 0.2 3.2 1 1 2 3 3 3 0 Putative small multi-drug export protein Phosphodiest PF01663.17 EMR73052.1 - 0.017 14.4 0.1 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Acetyltransf_1 PF00583.19 EMR73053.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF849 PF05853.7 EMR73060.1 - 4.4e-07 29.0 0.8 4.9e-07 28.9 0.2 1.3 2 0 0 2 2 2 1 Prokaryotic protein of unknown function (DUF849) Peptidase_M19 PF01244.16 EMR73061.1 - 1.1e-98 330.0 0.0 1.3e-98 329.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Plasmod_MYXSPDY PF07981.6 EMR73061.1 - 0.083 12.6 1.3 0.19 11.4 0.9 1.7 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Amidohydro_2 PF04909.9 EMR73061.1 - 0.15 11.6 0.0 2.4 7.6 0.0 2.1 1 1 0 1 1 1 0 Amidohydrolase Acetyltransf_9 PF13527.1 EMR73062.1 - 1.8e-09 37.5 0.0 6.5e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR73062.1 - 3.6e-05 23.8 0.0 0.0081 16.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR73062.1 - 0.00055 19.9 0.4 0.69 9.9 0.1 3.0 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR73062.1 - 0.0033 17.5 0.9 0.34 11.1 0.1 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Herpes_UL20 PF04544.7 EMR73063.1 - 0.1 12.4 1.3 0.15 11.9 0.9 1.3 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 BioY PF02632.9 EMR73064.1 - 0.074 12.7 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 BioY family Nudix_N_2 PF14803.1 EMR73065.1 - 0.0096 15.5 1.2 2.6 7.8 0.1 2.2 2 0 0 2 2 2 2 Nudix N-terminal zf-ribbon_3 PF13248.1 EMR73065.1 - 0.015 14.4 0.1 0.015 14.4 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.6 EMR73065.1 - 0.023 14.5 0.3 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Spt4 PF06093.8 EMR73065.1 - 0.026 14.3 0.2 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DZR PF12773.2 EMR73065.1 - 0.031 14.0 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.2 EMR73065.1 - 0.061 13.2 1.6 4.4 7.3 0.3 2.2 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_2 PF13240.1 EMR73065.1 - 0.071 12.6 0.9 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 EMR73065.1 - 0.072 12.8 0.6 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.2 EMR73065.1 - 0.11 12.3 0.1 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF164 PF02591.10 EMR73065.1 - 0.14 12.0 1.1 0.32 10.8 0.5 1.8 1 1 1 2 2 2 0 Putative zinc ribbon domain Auto_anti-p27 PF06677.7 EMR73065.1 - 0.19 11.5 2.3 0.32 10.7 1.6 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) YhfH PF14149.1 EMR73065.1 - 0.23 11.2 1.5 0.63 9.8 1.0 1.8 1 1 0 1 1 1 0 YhfH-like protein TF_Zn_Ribbon PF08271.7 EMR73065.1 - 0.35 10.2 3.9 0.6 9.4 2.2 1.8 1 1 1 2 2 2 0 TFIIB zinc-binding zf-U1 PF06220.7 EMR73065.1 - 0.61 9.6 3.7 0.55 9.8 1.7 1.6 2 0 0 2 2 2 0 U1 zinc finger Zn-ribbon_8 PF09723.5 EMR73065.1 - 1.8 8.5 4.1 35 4.4 2.8 2.2 1 1 0 1 1 1 0 Zinc ribbon domain TatD_DNase PF01026.16 EMR73079.1 - 1.4e-43 148.9 0.0 1.6e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EMR73079.1 - 0.023 14.2 0.1 0.13 11.7 0.0 2.0 1 1 1 2 2 2 0 Amidohydrolase HTH_45 PF14947.1 EMR73080.1 - 2.6e-19 68.8 0.1 2.9e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 EMR73080.1 - 1.4e-05 24.7 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) PadR PF03551.9 EMR73080.1 - 7.2e-05 22.4 0.2 0.00017 21.3 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_27 PF13463.1 EMR73080.1 - 0.0021 18.3 0.1 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Replic_Relax PF13814.1 EMR73080.1 - 0.0085 15.9 0.1 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Replication-relaxation DUF3045 PF11243.3 EMR73080.1 - 0.022 14.9 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) RQC PF09382.5 EMR73080.1 - 0.034 13.8 0.0 0.055 13.1 0.0 1.3 1 1 0 1 1 1 0 RQC domain HTH_IclR PF09339.5 EMR73080.1 - 0.04 13.5 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2250 PF10007.4 EMR73080.1 - 0.054 13.3 0.1 0.29 11.0 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF1495 PF07381.6 EMR73080.1 - 0.066 12.8 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) HTH_5 PF01022.15 EMR73080.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1628 PF07790.6 EMR73081.1 - 2.6e-06 28.0 1.3 5e-06 27.1 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1628) DUF417 PF04224.7 EMR73081.1 - 0.013 14.8 0.5 0.019 14.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF3112 PF11309.3 EMR73081.1 - 0.054 13.2 0.3 0.086 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF2393 PF09624.5 EMR73081.1 - 1.7 8.1 4.9 0.21 11.1 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Arch_flagellin PF01917.11 EMR73081.1 - 9.4 5.8 9.2 0.72 9.4 1.9 2.1 2 1 1 3 3 3 0 Archaebacterial flagellin Radical_SAM PF04055.16 EMR73084.1 - 6.9e-12 45.8 0.0 1.7e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.14 EMR73084.1 - 2.5e-10 40.2 0.0 2.5e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain Fer4_12 PF13353.1 EMR73084.1 - 0.055 13.5 0.2 6.3 6.9 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain DsbD PF02683.10 EMR73086.1 - 5.6e-17 62.0 21.6 7.7e-17 61.6 15.0 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region 7TMR-DISM_7TM PF07695.6 EMR73087.1 - 0.0033 17.1 5.0 0.0042 16.7 3.5 1.0 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF3792 PF12670.2 EMR73087.1 - 0.0037 17.1 12.2 0.0052 16.6 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) LtrA PF06772.6 EMR73087.1 - 0.021 13.7 0.9 0.025 13.5 0.6 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) DUF1275 PF06912.6 EMR73087.1 - 0.061 12.5 5.9 0.046 12.8 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) PHO4 PF01384.15 EMR73087.1 - 0.079 11.5 6.6 0.1 11.2 4.6 1.0 1 0 0 1 1 1 0 Phosphate transporter family Phage_holin_2 PF04550.7 EMR73087.1 - 0.6 10.2 5.8 2.8 8.0 0.4 2.2 1 1 1 2 2 2 0 Phage holin family 2 DUF2422 PF10337.4 EMR73087.1 - 0.71 8.6 2.8 0.9 8.2 1.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) MFS_1 PF07690.11 EMR73087.1 - 1.7 7.3 14.8 2 7.0 10.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2881 PF11087.3 EMR73087.1 - 3.9 7.0 8.7 1.3 8.5 3.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2881) DUF1469 PF07332.6 EMR73087.1 - 4.1 7.1 7.6 8.2 6.1 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) DUF4044 PF13253.1 EMR73090.1 - 4.5 6.4 6.2 1.1 8.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Fumarate_red_D PF02313.12 EMR73091.1 - 0.07 13.0 0.5 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit D DUF2665 PF11654.3 EMR73091.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) DUF3649 PF12365.3 EMR73091.1 - 0.77 9.3 9.5 1.4 8.5 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Glyco_trans_4_2 PF13477.1 EMR73092.1 - 0.033 14.0 0.0 0.049 13.4 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like NIR_SIR PF01077.17 EMR73092.1 - 0.067 12.5 0.2 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain RLL PF10036.4 EMR73092.1 - 0.2 11.0 3.4 0.26 10.6 2.4 1.1 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein DUF3596 PF12167.3 EMR73092.1 - 0.22 11.0 1.9 0.75 9.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3596) AHH PF14412.1 EMR73092.1 - 0.23 11.4 2.3 0.64 10.0 1.6 1.7 1 1 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Radial_spoke_3 PF06098.6 EMR73092.1 - 0.5 9.3 6.7 0.71 8.8 4.6 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 FAM165 PF14981.1 EMR73092.1 - 0.82 9.2 7.7 1.9 8.0 5.3 1.6 1 0 0 1 1 1 0 FAM165 family SpoIIIAC PF06686.6 EMR73093.1 - 0.014 15.1 2.3 0.054 13.3 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family MpPF26 PF07666.6 EMR73093.1 - 0.019 14.8 1.8 0.019 14.8 1.3 1.5 1 1 0 1 1 1 0 M penetrans paralogue family 26 DUF4064 PF13273.1 EMR73093.1 - 0.019 15.0 2.5 0.023 14.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1430 PF07242.6 EMR73093.1 - 0.046 13.7 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Halogen_Hydrol PF10112.4 EMR73093.1 - 0.089 12.1 0.1 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein AzlD PF05437.7 EMR73093.1 - 0.14 12.0 1.3 0.17 11.8 0.9 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF2207 PF09972.4 EMR73093.1 - 0.28 9.7 1.5 0.3 9.6 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CAAD PF14159.1 EMR73093.1 - 0.32 10.6 1.4 1 9.0 1.0 1.8 1 1 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SdpI PF13630.1 EMR73093.1 - 2.5 7.8 4.9 3.3 7.4 3.4 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family RnfC_N PF13375.1 EMR73094.1 - 0.00075 19.1 0.1 0.15 11.7 0.0 2.8 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EMR73094.1 - 0.017 14.7 8.2 6.5 6.4 0.0 4.7 3 1 1 4 4 4 0 Biotin-requiring enzyme MutL PF13941.1 EMR73095.1 - 1.2e-129 432.6 0.0 1.4e-129 432.3 0.0 1.0 1 0 0 1 1 1 1 MutL protein DUF1877 PF08974.5 EMR73096.1 - 0.099 12.2 0.2 0.11 12.1 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) Pribosyltran PF00156.22 EMR73097.1 - 6.9e-15 54.8 0.9 1.1e-14 54.2 0.6 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HTH_3 PF01381.17 EMR73097.1 - 0.00066 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix PRTase_2 PF15609.1 EMR73097.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.1 EMR73097.1 - 0.045 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HTH_5 PF01022.15 EMR73097.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family SHS2_Rpb7-N PF03876.12 EMR73098.1 - 1.6e-13 50.5 0.0 2.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMR73098.1 - 4.6e-11 42.6 0.2 1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Spt4 PF06093.8 EMR73099.1 - 9.7e-13 47.8 0.5 1.4e-12 47.3 0.3 1.3 1 1 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.10 EMR73099.1 - 0.0061 15.9 4.7 0.0084 15.5 3.3 1.2 1 0 0 1 1 1 1 RecR protein zf-C3HC4_3 PF13920.1 EMR73099.1 - 0.048 13.3 2.3 0.067 12.8 1.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2367 PF10164.4 EMR73099.1 - 0.16 11.8 0.8 0.26 11.1 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) DUF359 PF04019.7 EMR73100.1 - 6.1e-35 119.2 0.0 1.7e-34 117.8 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF359) Ribosomal_S24e PF01282.14 EMR73101.1 - 2e-19 69.1 0.0 2.7e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S27 PF01599.14 EMR73102.1 - 2.9e-16 59.0 4.4 3.6e-16 58.6 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a GCC2_GCC3 PF07699.8 EMR73102.1 - 0.00036 20.0 0.9 0.00046 19.7 0.6 1.2 1 0 0 1 1 1 1 GCC2 and GCC3 Nudix_N_2 PF14803.1 EMR73102.1 - 0.00073 19.1 1.6 0.14 11.8 0.1 2.2 2 0 0 2 2 2 2 Nudix N-terminal GFA PF04828.9 EMR73102.1 - 0.0011 18.8 2.7 0.21 11.5 0.2 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.14 EMR73102.1 - 0.0054 16.5 3.5 0.0078 15.9 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e Zn_Tnp_IS1595 PF12760.2 EMR73102.1 - 0.0056 16.4 1.5 0.0071 16.1 1.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DZR PF12773.2 EMR73102.1 - 0.0066 16.2 1.9 0.013 15.2 1.3 1.5 1 1 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EMR73102.1 - 0.03 13.5 2.7 2 7.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.4 EMR73102.1 - 0.049 13.4 0.2 0.052 13.3 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) IBR PF01485.16 EMR73102.1 - 0.05 13.4 0.3 0.063 13.1 0.2 1.2 1 0 0 1 1 1 0 IBR domain zf-C2HC5 PF06221.8 EMR73102.1 - 0.061 13.0 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_2 PF13240.1 EMR73102.1 - 0.063 12.7 3.5 2.1 7.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EMR73102.1 - 0.086 12.5 0.2 0.096 12.3 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EMR73102.1 - 0.12 12.0 1.9 0.18 11.4 1.2 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-ISL3 PF14690.1 EMR73102.1 - 0.23 11.5 5.2 1.5 8.9 0.3 2.2 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 ADK_lid PF05191.9 EMR73102.1 - 0.54 9.9 6.1 3.5 7.3 0.3 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_4 PF13894.1 EMR73102.1 - 0.7 10.3 3.5 5.2 7.6 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Mss51 PF13824.1 EMR73102.1 - 0.84 9.5 3.7 1.6 8.6 1.2 2.2 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Auto_anti-p27 PF06677.7 EMR73102.1 - 0.97 9.2 5.6 0.28 10.9 0.8 2.0 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2 PF00096.21 EMR73102.1 - 1.5 9.3 6.7 1.5 9.3 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_ribbon_recom PF13408.1 EMR73102.1 - 3 8.1 8.5 3.1 8.1 0.6 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain HAD_2 PF13419.1 EMR73103.1 - 3.6e-15 56.6 0.0 4.3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR73103.1 - 1.1e-07 32.4 0.0 3.6e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR73103.1 - 1.4e-06 27.8 0.1 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMR73103.1 - 4.8e-05 23.6 0.0 6.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EMR73103.1 - 0.0012 18.4 0.0 0.077 12.6 0.0 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.2 EMR73103.1 - 0.14 11.7 0.2 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Rhomboid PF01694.17 EMR73104.1 - 5.4e-24 84.8 14.8 5.4e-24 84.8 10.3 1.7 2 1 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 EMR73104.1 - 0.018 15.3 0.1 0.018 15.3 0.1 2.7 3 1 2 5 5 5 0 Eukaryotic integral membrane protein (DUF1751) DUF843 PF05814.6 EMR73104.1 - 0.069 12.9 3.7 0.54 10.0 0.4 2.7 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF2530 PF10745.4 EMR73104.1 - 4.6 7.2 6.2 0.36 10.8 0.5 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) tRNA-synt_1f PF01921.13 EMR73105.1 - 1.7e-99 332.9 0.0 2.5e-99 332.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) Tautomerase PF01361.16 EMR73106.1 - 5.3e-14 51.5 0.0 5.6e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 EMR73106.1 - 4.4e-07 29.8 0.0 5e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme DUF1904 PF08921.6 EMR73106.1 - 0.00086 19.3 0.0 0.00092 19.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1904) TIMP PF00965.12 EMR73106.1 - 0.078 12.5 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase Toxin_8 PF07365.7 EMR73106.1 - 0.096 12.6 0.3 0.15 12.0 0.2 1.4 1 1 0 1 1 1 0 Alpha conotoxin precursor HTH_AsnC-type PF13404.1 EMR73107.1 - 9.4e-11 41.0 0.3 5.7e-05 22.5 0.0 2.5 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EMR73107.1 - 5.8e-09 35.2 0.4 0.0034 16.7 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 EMR73107.1 - 8.6e-05 22.2 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain TrmB PF01978.14 EMR73107.1 - 0.0011 18.5 0.1 0.31 10.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.11 EMR73107.1 - 0.0021 17.3 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_27 PF13463.1 EMR73107.1 - 0.0035 17.6 0.1 0.24 11.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain DUF2250 PF10007.4 EMR73107.1 - 0.015 15.1 0.1 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_10 PF04967.7 EMR73107.1 - 0.022 14.3 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain Sigma70_r4_2 PF08281.7 EMR73107.1 - 0.026 13.9 0.0 5.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_30 PF13556.1 EMR73107.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.1 EMR73107.1 - 0.15 12.1 0.0 8.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TMEM52 PF14979.1 EMR73109.1 - 0.0036 17.2 1.0 0.0041 17.0 0.0 1.5 2 0 0 2 2 2 1 Transmembrane 52 FtsX PF02687.16 EMR73109.1 - 1.8 8.3 7.0 0.22 11.2 1.0 2.0 2 0 0 2 2 2 0 FtsX-like permease family ABC2_membrane PF01061.19 EMR73109.1 - 7.4 5.6 12.3 7.4 5.6 2.1 2.1 2 0 0 2 2 2 0 ABC-2 type transporter tRNA_int_endo PF01974.12 EMR73110.1 - 3.2e-13 49.2 0.1 4.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EMR73110.1 - 8.8e-10 38.0 0.4 3.3e-08 32.9 0.0 2.4 2 1 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain tRNA_int_end_N2 PF12928.2 EMR73110.1 - 0.0042 16.5 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA-synt_His PF13393.1 EMR73111.1 - 1.5e-55 188.4 0.0 1.8e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMR73111.1 - 2e-18 66.5 0.0 1.3e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMR73111.1 - 1.8e-16 59.8 1.5 2e-16 59.6 0.2 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.15 EMR73111.1 - 9.4e-05 21.7 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EMR73111.1 - 0.062 12.0 0.1 1 8.0 0.0 2.6 3 1 0 3 3 3 0 tRNA synthetases class II (D, K and N) Zn-ribbon_8 PF09723.5 EMR73112.1 - 0.025 14.5 3.5 1.8 8.6 0.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EMR73112.1 - 0.03 14.1 3.3 0.082 12.7 2.3 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_4 PF13894.1 EMR73112.1 - 0.077 13.3 1.0 5.2 7.6 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DnaJ_CXXCXGXG PF00684.14 EMR73112.1 - 0.1 12.6 0.9 0.11 12.5 0.6 1.1 1 0 0 1 1 1 0 DnaJ central domain zf-H2C2_2 PF13465.1 EMR73112.1 - 0.21 11.9 0.3 0.21 11.9 0.2 2.8 2 1 1 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EMR73112.1 - 0.24 11.7 4.8 0.33 11.3 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-IS66 PF13005.2 EMR73112.1 - 0.31 11.0 1.8 1.8 8.5 0.1 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Zn_ribbon_recom PF13408.1 EMR73112.1 - 0.32 11.2 1.9 0.4 10.9 1.3 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-MYND PF01753.13 EMR73112.1 - 0.46 10.4 2.4 0.92 9.4 1.6 1.6 1 1 0 1 1 1 0 MYND finger zf-ISL3 PF14690.1 EMR73112.1 - 0.53 10.3 2.8 4.5 7.3 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 A2L_zn_ribbon PF08792.5 EMR73112.1 - 1.4 8.4 4.5 2.8 7.4 0.4 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-HIT PF04438.11 EMR73112.1 - 1.8 8.2 5.4 7 6.3 0.4 2.3 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_6 PF13912.1 EMR73112.1 - 3 7.8 5.5 1.1 9.2 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-NADH-PPase PF09297.6 EMR73112.1 - 5.8 6.5 5.8 1.2 8.7 1.0 1.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Response_reg PF00072.19 EMR73113.1 - 5.1e-21 74.7 0.1 6e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_31 PF13847.1 EMR73113.1 - 0.006 16.1 0.1 0.0069 15.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain HAD_2 PF13419.1 EMR73113.1 - 0.046 13.9 0.0 0.094 12.9 0.0 1.5 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase OKR_DC_1_N PF03709.10 EMR73113.1 - 0.058 13.4 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain tRNA-synt_2c PF01411.14 EMR73114.1 - 1.2e-08 33.6 0.0 1.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EMR73114.1 - 4.1e-07 29.7 0.7 1.7e-06 27.8 0.1 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain SecY PF00344.15 EMR73115.1 - 2.6e-85 286.3 18.3 3.4e-85 286.0 12.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMR73115.1 - 1.6e-13 49.9 0.1 5.1e-13 48.2 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p RseC_MucC PF04246.7 EMR73115.1 - 0.32 10.5 7.0 0.12 11.9 0.3 2.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ribosomal_L18e PF00828.14 EMR73116.1 - 2.4e-20 73.1 0.0 3.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L30 PF00327.15 EMR73117.1 - 7e-13 47.9 0.1 1.2e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.15 EMR73118.1 - 6.1e-24 83.5 0.4 1.2e-23 82.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EMR73118.1 - 8.5e-23 79.4 0.5 1.7e-22 78.4 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Pox_D3 PF04580.8 EMR73118.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein Ribosomal_L18p PF00861.17 EMR73119.1 - 5.2e-36 123.4 0.1 6.5e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EMR73119.1 - 5.8e-07 29.9 0.1 9.7e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L19e PF01280.15 EMR73120.1 - 2.6e-51 173.2 13.9 2.9e-51 173.1 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DUF3391 PF11871.3 EMR73120.1 - 0.00042 20.5 1.3 0.0011 19.1 0.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3391) EFhand_Ca_insen PF08726.5 EMR73120.1 - 0.058 13.3 0.1 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF4019 PF13211.1 EMR73120.1 - 0.099 12.9 1.1 0.19 11.9 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4019) Ribosomal_L32e PF01655.13 EMR73121.1 - 2.1e-40 137.2 0.9 2.9e-40 136.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L32 Ribosomal_L6 PF00347.18 EMR73122.1 - 3.4e-23 81.9 4.3 7.1e-13 48.8 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4218 PF13960.1 EMR73122.1 - 0.064 12.6 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Ribosomal_S8 PF00410.14 EMR73123.1 - 2.1e-21 76.0 0.0 2.7e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.16 EMR73124.1 - 4.2e-16 58.0 6.2 4.3e-16 58.0 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e A2L_zn_ribbon PF08792.5 EMR73124.1 - 0.077 12.4 0.8 0.11 11.9 0.6 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain Toxin_46 PF15526.1 EMR73124.1 - 0.11 12.7 0.3 2.5 8.3 0.1 2.1 2 0 0 2 2 2 0 Putative toxin 46 zf-ribbon_3 PF13248.1 EMR73124.1 - 0.16 11.2 2.1 0.48 9.7 1.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-tcix PF14952.1 EMR73124.1 - 0.42 9.9 6.5 1.1 8.6 4.5 1.8 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Ribosomal_L5_C PF00673.16 EMR73125.1 - 1.6e-22 79.0 0.0 3e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMR73125.1 - 5.1e-13 48.5 0.1 9.1e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S4e PF00900.15 EMR73126.1 - 6.7e-27 92.9 0.0 1.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EMR73126.1 - 9.8e-14 50.9 11.0 2.2e-13 49.7 7.6 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EMR73126.1 - 1.5e-11 43.5 0.1 2.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EMR73126.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 S4 domain DUF2382 PF09557.5 EMR73127.1 - 0.04 13.8 0.4 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2382) Ribosomal_L14 PF00238.14 EMR73128.1 - 9.6e-33 112.5 0.0 1.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RsgI_N PF12791.2 EMR73128.1 - 0.042 13.5 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Ribosomal_S17 PF00366.15 EMR73129.1 - 4.6e-27 93.8 1.6 5.6e-27 93.5 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 UPF0086 PF01868.11 EMR73130.1 - 3.8e-26 90.5 0.1 4.2e-26 90.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.18 EMR73131.1 - 3.4e-18 65.0 2.6 4e-18 64.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.8 EMR73131.1 - 0.078 12.8 1.1 0.21 11.5 0.1 1.8 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_S9 PF00380.14 EMR73131.1 - 0.091 13.0 0.0 0.091 13.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S9/S16 HHH_8 PF14716.1 EMR73131.1 - 0.098 12.8 0.1 0.22 11.7 0.0 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix domain DUF2161 PF09929.4 EMR73131.1 - 0.11 12.4 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) DUF2387 PF09526.5 EMR73136.1 - 0.0038 17.1 0.2 0.0048 16.7 0.2 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) TF_Zn_Ribbon PF08271.7 EMR73136.1 - 0.0046 16.2 3.7 0.008 15.4 2.6 1.5 1 1 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.1 EMR73136.1 - 0.0065 16.7 1.9 0.008 16.4 1.4 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar DUF3797 PF12677.2 EMR73136.1 - 0.0087 15.6 0.7 1.7 8.3 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3797) RNA_POL_M_15KD PF02150.11 EMR73136.1 - 0.02 14.5 1.0 0.03 13.9 0.7 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EMR73136.1 - 0.022 14.5 0.5 0.028 14.2 0.4 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMR73136.1 - 0.033 14.1 1.1 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EMR73136.1 - 0.036 13.7 0.5 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 EMR73136.1 - 0.052 13.2 0.3 0.059 13.0 0.2 1.0 1 0 0 1 1 1 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.1 EMR73136.1 - 0.24 10.6 4.2 0.46 9.7 2.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 EMR73136.1 - 0.74 9.5 6.6 5.9 6.6 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-CSL PF05207.8 EMR73136.1 - 1.5 8.4 4.3 0.31 10.5 0.2 1.8 1 1 1 2 2 2 0 CSL zinc finger zf-H2C2_2 PF13465.1 EMR73136.1 - 4.6 7.7 5.8 4.7 7.6 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain XPA_N PF01286.13 EMR73136.1 - 4.7 6.9 6.8 14 5.4 1.3 2.4 2 1 0 2 2 2 0 XPA protein N-terminal Fer4 PF00037.22 EMR73137.1 - 7.1e-12 44.4 15.4 1e-05 24.9 0.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EMR73137.1 - 6e-10 38.8 11.8 7.6e-10 38.4 8.2 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMR73137.1 - 4.1e-08 32.8 10.8 4.1e-08 32.8 7.5 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EMR73137.1 - 4.5e-08 32.6 16.7 0.00015 21.5 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EMR73137.1 - 7.5e-08 32.6 40.1 1e-05 25.8 10.9 1.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMR73137.1 - 2.4e-07 30.2 12.3 0.0023 17.7 2.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EMR73137.1 - 5.8e-06 26.4 16.2 8.2e-06 25.9 11.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMR73137.1 - 2.6e-05 24.8 15.3 0.012 16.3 4.7 2.5 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EMR73137.1 - 0.00094 19.1 14.5 0.0074 16.3 10.4 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 EMR73137.1 - 0.002 18.3 14.0 0.014 15.6 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EMR73137.1 - 0.0022 18.3 12.8 0.042 14.2 0.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EMR73137.1 - 0.011 16.1 12.6 0.064 13.6 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.1 EMR73137.1 - 0.056 13.8 14.3 0.77 10.2 3.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EMR73137.1 - 0.073 13.6 15.1 0.42 11.2 4.2 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_11 PF13247.1 EMR73137.1 - 0.086 12.7 8.7 0.12 12.2 6.0 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain CBM_10 PF02013.11 EMR73137.1 - 0.28 11.4 0.2 0.28 11.4 0.1 2.6 3 1 0 3 3 3 0 Cellulose or protein binding domain C1_1 PF00130.17 EMR73137.1 - 3.8 7.3 11.2 7.1 6.4 7.7 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Evr1_Alr PF04777.8 EMR73138.1 - 0.038 13.8 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Erv1 / Alr family Chordopox_A13L PF05961.6 EMR73138.1 - 0.065 13.1 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Baculo_11_kDa PF06143.6 EMR73138.1 - 0.19 11.1 1.6 0.23 10.8 1.1 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family GrpB PF04229.9 EMR73141.1 - 2.9e-39 134.4 0.0 3.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 GrpB protein A-2_8-polyST PF07388.6 EMR73142.1 - 0.096 11.0 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) Drf_FH3 PF06367.11 EMR73143.1 - 0.033 13.5 0.5 0.071 12.5 0.4 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain Bac_rhamnosid PF05592.6 EMR73143.1 - 0.13 10.4 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase SURF2 PF05477.6 EMR73144.1 - 0.053 12.6 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF3420 PF11900.3 EMR73145.1 - 0.0011 19.0 0.4 0.0017 18.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3420) PsbU PF06514.6 EMR73145.1 - 0.033 14.0 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) AAA PF00004.24 EMR73146.1 - 2.6e-98 325.3 0.0 2.6e-48 163.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMR73146.1 - 1e-29 102.2 0.1 4.9e-29 100.1 0.1 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.1 EMR73146.1 - 2.5e-15 56.9 0.0 4.3e-06 26.8 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EMR73146.1 - 9.7e-15 54.2 0.0 7.4e-08 31.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus CDC48_2 PF02933.12 EMR73146.1 - 1.5e-14 53.3 0.1 5.1e-14 51.6 0.1 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EMR73146.1 - 5.3e-12 46.0 0.0 0.001 19.2 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EMR73146.1 - 1e-11 44.7 0.0 2.9e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMR73146.1 - 3.7e-11 42.5 0.0 0.00012 21.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EMR73146.1 - 3.7e-11 42.3 0.4 1.7e-05 23.7 0.0 2.7 3 0 0 3 3 3 2 TIP49 C-terminus AAA_33 PF13671.1 EMR73146.1 - 3.9e-11 43.0 0.0 0.00027 20.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMR73146.1 - 4.4e-11 42.6 0.3 0.00091 18.9 0.0 4.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMR73146.1 - 1.5e-10 41.9 0.0 0.0011 19.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EMR73146.1 - 2.7e-10 40.4 0.0 1.4e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.13 EMR73146.1 - 2.3e-08 33.8 0.0 0.00079 19.0 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EMR73146.1 - 3e-08 33.8 0.0 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EMR73146.1 - 1.4e-07 31.8 0.0 0.04 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EMR73146.1 - 1.4e-07 31.2 0.1 0.088 12.4 0.0 3.8 4 0 0 4 4 4 2 NACHT domain IstB_IS21 PF01695.12 EMR73146.1 - 2.4e-07 30.3 0.1 0.021 14.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EMR73146.1 - 2.9e-07 30.6 0.0 0.038 14.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EMR73146.1 - 3.7e-07 29.8 2.4 0.018 14.7 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Sigma54_activ_2 PF14532.1 EMR73146.1 - 1.5e-06 28.3 0.0 0.018 15.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 EMR73146.1 - 1.5e-06 27.5 0.5 0.049 12.7 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EMR73146.1 - 2.6e-06 27.3 0.0 0.036 13.7 0.0 3.5 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activat PF00158.21 EMR73146.1 - 3.7e-06 26.5 0.0 0.029 13.8 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EMR73146.1 - 4.7e-06 26.9 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter NTPase_1 PF03266.10 EMR73146.1 - 1.2e-05 25.1 0.4 4.7 6.8 0.0 4.3 3 1 1 4 4 4 0 NTPase AAA_3 PF07726.6 EMR73146.1 - 2e-05 24.2 0.0 0.24 11.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EMR73146.1 - 3.1e-05 22.9 0.0 0.22 10.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.1 EMR73146.1 - 4.6e-05 22.9 3.7 1.7 8.0 0.1 4.3 2 2 1 4 4 4 1 AAA domain KaiC PF06745.8 EMR73146.1 - 9.7e-05 21.5 0.6 1.3 8.1 0.0 3.7 3 1 1 4 4 4 2 KaiC PhoH PF02562.11 EMR73146.1 - 0.0001 21.6 0.1 0.46 9.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein UPF0079 PF02367.12 EMR73146.1 - 0.0011 18.6 0.1 2.5 7.7 0.0 2.9 2 1 1 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 EMR73146.1 - 0.0018 17.9 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin2 PF13189.1 EMR73146.1 - 0.0018 18.1 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 EMR73146.1 - 0.0019 18.0 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Bac_DnaA PF00308.13 EMR73146.1 - 0.0019 17.8 0.0 1.8 8.1 0.0 3.1 2 1 0 3 3 3 1 Bacterial dnaA protein AAA_11 PF13086.1 EMR73146.1 - 0.0021 17.6 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain DAP3 PF10236.4 EMR73146.1 - 0.0026 16.7 0.0 0.99 8.2 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 EMR73146.1 - 0.0029 17.1 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EMR73146.1 - 0.0031 16.4 0.0 0.55 9.1 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.10 EMR73146.1 - 0.0057 16.5 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EMR73146.1 - 0.0069 15.3 0.0 2 7.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 EMR73146.1 - 0.0076 14.9 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AFG1_ATPase PF03969.11 EMR73146.1 - 0.0097 14.7 0.0 1.9 7.1 0.0 2.4 2 1 0 2 2 2 1 AFG1-like ATPase AAA_24 PF13479.1 EMR73146.1 - 0.043 13.3 0.0 11 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EMR73146.1 - 0.05 12.4 0.0 8.5 5.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EMR73146.1 - 0.061 12.9 0.0 14 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EMR73146.1 - 0.073 12.2 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EMR73146.1 - 0.079 12.4 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EMR73146.1 - 0.11 11.4 0.0 3.6 6.5 0.0 2.3 2 1 0 2 2 2 0 KAP family P-loop domain Zot PF05707.7 EMR73146.1 - 0.14 11.6 0.2 46 3.4 0.0 3.7 2 2 0 2 2 2 0 Zonular occludens toxin (Zot) Torsin PF06309.6 EMR73146.1 - 0.15 11.9 0.0 9.8 6.0 0.0 2.6 2 0 0 2 2 2 0 Torsin Aminotran_3 PF00202.16 EMR73147.1 - 3.5e-98 328.5 0.0 4.1e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMR73147.1 - 0.018 13.9 0.0 0.36 9.7 0.0 2.3 2 1 0 2 2 2 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMR73147.1 - 0.11 11.5 0.0 0.32 10.0 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Peptidase_M20 PF01546.23 EMR73148.1 - 1.1e-22 80.4 0.1 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR73148.1 - 5.5e-13 48.6 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EMR73148.1 - 0.0038 16.0 0.6 0.18 10.5 0.0 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase HAD_2 PF13419.1 EMR73150.1 - 4.2e-25 88.9 0.0 5.7e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR73150.1 - 2.3e-09 38.0 0.0 2.4e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR73150.1 - 3e-09 36.4 0.0 5.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Cpn60_TCP1 PF00118.19 EMR73151.1 - 5.1e-168 559.6 10.7 5.8e-168 559.4 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2262 PF10020.4 EMR73151.1 - 0.015 15.5 1.4 0.2 11.8 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2262) TroA PF01297.12 EMR73151.1 - 0.061 12.5 0.3 0.66 9.1 0.2 2.3 1 1 0 1 1 1 0 Periplasmic solute binding protein family Fer4_21 PF14697.1 EMR73153.1 - 4e-05 23.3 3.1 4.6e-05 23.1 2.2 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EMR73153.1 - 0.001 19.4 3.4 0.0013 19.0 2.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMR73153.1 - 0.014 16.1 5.5 0.39 11.4 2.8 2.1 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_11 PF13247.1 EMR73153.1 - 0.06 13.2 1.5 0.066 13.1 1.0 1.1 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMR73153.1 - 0.17 12.1 4.1 0.22 11.7 2.8 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.22 EMR73153.1 - 0.24 11.0 5.3 0.75 9.4 1.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EMR73153.1 - 4.5 7.3 6.2 14 5.7 1.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain HxlR PF01638.12 EMR73154.1 - 1e-07 31.5 0.0 1e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.9 EMR73154.1 - 0.0019 17.9 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family TPP_enzyme_C PF02775.16 EMR73155.1 - 0.011 15.3 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMR73156.1 - 8.2e-25 87.1 0.3 3.1e-24 85.2 0.2 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EMR73156.1 - 0.038 12.9 0.1 0.093 11.6 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Takusan PF04822.8 EMR73156.1 - 0.08 12.7 0.8 0.14 11.9 0.6 1.4 1 0 0 1 1 1 0 Takusan E1_dh PF00676.15 EMR73156.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Antitoxin-MazE PF04014.13 EMR73157.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.5 1 1 0 1 1 1 0 Antidote-toxin recognition MazE Glycos_transf_2 PF00535.21 EMR73158.1 - 1.3e-23 83.5 0.4 1.8e-23 83.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR73158.1 - 9.8e-10 38.6 0.0 1.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMR73158.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EMR73158.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR73159.1 - 2.9e-06 27.2 0.0 9.2e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMR73159.1 - 0.0016 18.2 0.0 0.0024 17.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_4 PF13439.1 EMR73160.1 - 0.00046 19.9 0.0 0.00046 19.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase Family 4 HTH_45 PF14947.1 EMR73165.1 - 1.8e-12 46.8 0.1 1.8e-12 46.8 0.1 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.1 EMR73165.1 - 0.064 12.6 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ILVD_EDD PF00920.16 EMR73166.1 - 2e-84 283.8 0.2 2.3e-84 283.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1041 PF06292.12 EMR73167.1 - 0.007 16.5 0.2 3.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1041) FUR PF01475.14 EMR73167.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Ferric uptake regulator family Mrr_N PF14338.1 EMR73167.1 - 0.012 15.7 0.3 3 8.0 0.0 2.7 2 2 0 2 2 2 0 Mrr N-terminal domain z-alpha PF02295.12 EMR73167.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain HTH_36 PF13730.1 EMR73167.1 - 0.17 12.0 0.8 0.44 10.7 0.5 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.1 EMR73169.1 - 1.9e-22 78.8 0.1 2e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DUF2250 PF10007.4 EMR73169.1 - 0.13 12.2 0.4 0.3 11.0 0.3 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 EMR73169.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF91 PF01939.11 EMR73170.1 - 7.3e-63 211.7 0.0 9.3e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF91 HSDR_N PF04313.9 EMR73170.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1703 PF08011.6 EMR73170.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1703) PDDEXK_4 PF14281.1 EMR73170.1 - 0.046 13.5 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EMR73170.1 - 0.047 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 Cys_rich_KTR PF14205.1 EMR73173.1 - 0.055 12.9 0.1 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich KTR zinc_ribbon_6 PF14599.1 EMR73173.1 - 0.13 12.1 0.1 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon Topoisom_bac PF01131.15 EMR73174.1 - 2.1e-14 53.1 0.1 2.6e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-C4_Topoisom PF01396.14 EMR73174.1 - 6.9e-06 25.4 12.1 0.00036 19.9 1.4 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger DNA_ligase_ZBD PF03119.11 EMR73174.1 - 0.0019 17.8 1.2 0.0019 17.8 0.8 2.6 3 0 0 3 3 3 1 NAD-dependent DNA ligase C4 zinc finger domain Auto_anti-p27 PF06677.7 EMR73174.1 - 0.0024 17.5 2.2 0.031 14.0 0.2 2.5 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HypA PF01155.14 EMR73174.1 - 0.16 11.6 0.7 5.5 6.7 0.1 2.5 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EMR73174.1 - 0.17 11.9 4.8 0.62 10.1 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC4_3 PF13920.1 EMR73174.1 - 0.19 11.4 2.7 2.8 7.6 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Lar_restr_allev PF14354.1 EMR73174.1 - 0.2 12.0 4.8 0.4 11.0 0.6 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 EMR73174.1 - 0.24 10.9 2.4 4.4 6.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EMR73174.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.0 2 0 0 2 2 2 0 Nudix N-terminal Zn-ribbon_8 PF09723.5 EMR73174.1 - 0.87 9.5 3.2 6.5 6.7 0.1 2.5 3 0 0 3 3 2 0 Zinc ribbon domain zf-TFIIB PF13453.1 EMR73174.1 - 6.3 6.0 7.3 9.4 5.5 1.0 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger Topoisom_bac PF01131.15 EMR73175.1 - 1.2e-77 261.4 0.0 1.5e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EMR73175.1 - 6.6e-11 42.0 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Exo_endo_phos PF03372.18 EMR73176.1 - 1.4e-08 34.9 0.3 1.9e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DapB_N PF01113.15 EMR73177.1 - 1.3e-09 38.0 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EMR73177.1 - 0.00016 22.1 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EMR73177.1 - 0.0011 19.3 0.0 0.0031 17.8 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 EMR73177.1 - 0.0099 16.3 0.1 0.031 14.7 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain bPH_6 PF10756.4 EMR73179.1 - 0.0024 17.7 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial PH domain Antitoxin-MazE PF04014.13 EMR73179.1 - 0.05 13.3 0.1 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 Antidote-toxin recognition MazE Pyr_redox_2 PF07992.9 EMR73180.1 - 2.2e-32 112.5 0.0 1.5e-31 109.9 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR73180.1 - 4.7e-17 62.1 0.3 1.9e-14 53.8 0.0 3.2 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMR73180.1 - 2.4e-15 56.4 0.0 1e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DAO PF01266.19 EMR73180.1 - 9.7e-11 41.1 1.4 0.0055 15.6 0.0 3.5 3 1 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR73180.1 - 1.3e-06 28.6 0.1 0.0015 18.6 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR73180.1 - 0.00018 20.4 0.1 0.5 9.1 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EMR73180.1 - 0.00021 21.2 0.0 0.46 10.5 0.0 3.0 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EMR73180.1 - 0.00022 20.4 0.0 0.094 11.8 0.0 2.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMR73180.1 - 0.00075 18.0 0.1 2.2 6.6 0.0 3.4 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 EMR73180.1 - 0.0099 15.0 1.7 5.5 6.0 0.0 3.5 4 0 0 4 4 4 1 Thi4 family NAD_binding_7 PF13241.1 EMR73180.1 - 0.01 16.0 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.7 EMR73180.1 - 0.025 13.9 0.0 1.2 8.4 0.0 2.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 EMR73180.1 - 0.027 14.2 1.0 7.5 6.2 0.0 3.9 5 0 0 5 5 4 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 EMR73180.1 - 0.053 13.5 0.1 1.7 8.5 0.0 2.7 3 0 0 3 3 3 0 NADH(P)-binding K_oxygenase PF13434.1 EMR73180.1 - 0.06 12.2 0.0 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AdoHcyase_NAD PF00670.16 EMR73180.1 - 0.07 12.9 0.6 0.35 10.6 0.0 2.4 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.15 EMR73180.1 - 0.1 12.7 0.0 4 7.5 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EMR73180.1 - 0.65 8.7 4.5 9.7 4.9 0.1 3.4 2 2 2 5 5 5 0 Glucose inhibited division protein A Peptidase_S24 PF00717.18 EMR73181.1 - 3.5e-08 32.9 0.1 5.8e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like B-block_TFIIIC PF04182.7 EMR73182.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.7 EMR73182.1 - 0.0016 17.6 2.5 0.06 12.5 0.3 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit MarR_2 PF12802.2 EMR73182.1 - 0.11 12.1 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family TBP PF00352.16 EMR73183.1 - 2e-64 212.9 0.4 4.8e-31 105.9 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMR73183.1 - 7.2e-07 29.1 0.0 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) HTH_Crp_2 PF13545.1 EMR73183.1 - 0.00091 18.9 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF1133 PF06576.6 EMR73183.1 - 0.025 13.7 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) HTH_24 PF13412.1 EMR73183.1 - 0.18 11.2 0.6 0.29 10.5 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2079 PF09852.4 EMR73185.1 - 5.1e-09 35.3 14.6 5.5e-09 35.2 10.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) Sigma_reg_N PF13800.1 EMR73185.1 - 8.6 6.4 12.2 9 6.4 3.7 3.0 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Phage_integrase PF00589.17 EMR73186.1 - 1.7e-13 50.6 0.3 3.7e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family SseC PF04888.7 EMR73186.1 - 0.031 13.6 4.6 0.059 12.7 3.2 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF1548 PF07579.6 EMR73186.1 - 0.031 14.3 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) ADIP PF11559.3 EMR73186.1 - 0.032 14.1 1.8 0.032 14.1 1.2 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_int_SAM_1 PF02899.12 EMR73186.1 - 0.051 13.7 0.1 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain IncA PF04156.9 EMR73186.1 - 0.12 12.0 1.1 0.46 10.0 1.0 1.7 2 0 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 EMR73186.1 - 0.12 12.3 3.2 0.37 10.7 2.2 1.9 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.3 EMR73186.1 - 0.29 10.9 8.6 1.5 8.7 0.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding 60KD_IMP PF02096.15 EMR73186.1 - 0.42 10.2 2.1 0.83 9.2 1.5 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein CCDC92 PF14916.1 EMR73186.1 - 2.4 7.8 6.7 5.6 6.6 0.2 3.1 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DivIC PF04977.10 EMR73186.1 - 2.6 7.5 7.2 22 4.6 5.0 2.4 1 1 0 1 1 1 0 Septum formation initiator SAB PF04382.8 EMR73188.1 - 0.0025 17.4 2.2 0.0029 17.2 1.0 1.5 1 1 0 1 1 1 1 SAB domain Nairo_nucleo PF02477.10 EMR73188.1 - 0.026 13.2 0.1 0.026 13.2 0.1 1.0 1 0 0 1 1 1 0 Nucleocapsid N protein DUF2762 PF10960.3 EMR73188.1 - 0.19 11.4 1.3 0.24 11.1 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2762) Apq12 PF12716.2 EMR73195.1 - 0.13 11.9 0.3 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Tox-GHH PF15636.1 EMR73196.1 - 0.075 12.6 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin CAAP1 PF15335.1 EMR73197.1 - 0.057 13.6 0.1 0.1 12.8 0.0 1.5 1 1 1 2 2 2 0 Caspase activity and apoptosis inhibitor 1 DUF1492 PF07374.6 EMR73197.1 - 0.061 13.4 0.1 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) VPR PF00522.13 EMR73197.1 - 0.062 13.1 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 VPR/VPX protein Mating_N PF12731.2 EMR73197.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein beta 1 Kri1 PF05178.7 EMR73197.1 - 0.16 12.2 0.8 0.22 11.8 0.6 1.2 1 0 0 1 1 1 0 KRI1-like family DbpA PF03880.10 EMR73198.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Peptidase_M50B PF13398.1 EMR73201.1 - 0.079 12.3 8.0 0.34 10.2 5.5 2.1 1 1 0 1 1 1 0 Peptidase M50B-like Peptidase_M50 PF02163.17 EMR73201.1 - 0.21 10.5 3.8 0.11 11.4 0.3 2.1 1 1 1 2 2 2 0 Peptidase family M50 Ribosomal_S5 PF00333.15 EMR73202.1 - 0.013 15.1 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain DUF4064 PF13273.1 EMR73203.1 - 0.052 13.6 1.7 0.059 13.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1269 PF06897.7 EMR73203.1 - 0.14 12.2 0.3 0.17 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DUF1206 PF06724.6 EMR73203.1 - 0.17 11.6 3.1 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF1049 PF06305.6 EMR73203.1 - 5.6 6.5 5.5 15 5.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TraY PF05509.6 EMR73204.1 - 0.093 12.5 0.4 0.2 11.4 0.1 1.7 1 1 0 1 1 1 0 TraY domain FAIM1 PF06905.8 EMR73204.1 - 0.14 11.2 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) GerE PF00196.14 EMR73205.1 - 0.11 11.7 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family ABC_tran PF00005.22 EMR73206.1 - 1.1e-28 100.2 0.0 2.5e-28 99.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EMR73206.1 - 5.7e-15 56.0 3.4 9.5e-11 42.1 0.4 2.3 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 EMR73206.1 - 0.0021 17.2 0.0 0.054 12.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EMR73206.1 - 0.0066 16.7 2.5 0.0094 16.2 1.5 1.7 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EMR73206.1 - 0.021 14.2 0.1 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EMR73206.1 - 0.056 12.9 0.3 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EMR73206.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMR73206.1 - 0.11 12.6 0.5 0.48 10.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EMR73206.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EMR73206.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EMR73206.1 - 0.21 11.8 4.9 0.28 11.3 0.9 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane PF01061.19 EMR73207.1 - 1e-30 106.5 14.1 1e-30 106.5 9.8 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EMR73207.1 - 1.6e-16 60.2 23.8 1.6e-16 60.2 16.5 1.4 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 EMR73207.1 - 1.4e-06 27.4 24.4 2.4e-06 26.6 16.9 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein CcmB PF03379.8 EMR73207.1 - 8.4e-06 25.1 14.1 1.3e-05 24.5 9.7 1.6 1 1 0 1 1 1 1 CcmB protein DUF2074 PF09847.4 EMR73207.1 - 1.8e-05 23.7 7.8 1.8e-05 23.7 5.4 1.9 1 1 1 2 2 2 1 Predicted permease (DUF2074) CAAD PF14159.1 EMR73207.1 - 0.86 9.2 4.5 2.5 7.7 3.1 1.9 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2079 PF09852.4 EMR73208.1 - 2.3e-18 66.1 0.2 3e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) Asp_Glu_race PF01177.17 EMR73209.1 - 1.3e-39 136.3 0.1 1.5e-39 136.1 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pribosyltran PF00156.22 EMR73210.1 - 4e-08 33.0 0.3 2e-07 30.8 0.6 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 EMR73210.1 - 4.3e-06 26.4 0.0 8.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMR73210.1 - 0.00051 18.8 0.0 0.68 8.5 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMR73210.1 - 0.0068 16.3 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain tRNA_edit PF04073.10 EMR73211.1 - 8.3e-27 93.4 0.1 1.1e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Aminotran_5 PF00266.14 EMR73212.1 - 2.9e-52 177.6 0.0 3.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMR73212.1 - 7.5e-07 27.7 0.0 1.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EMR73212.1 - 8.1e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMR73212.1 - 2e-06 27.0 0.0 5.4e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMR73212.1 - 7.2e-05 21.9 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_31 PF13847.1 EMR73213.1 - 2.4e-08 33.7 0.0 2.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EMR73213.1 - 4.5e-08 32.6 0.0 3.1e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 EMR73213.1 - 2.9e-07 29.8 0.0 3.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EMR73213.1 - 1.1e-06 29.2 0.0 1.4e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR73213.1 - 1.5e-06 28.4 0.0 2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR73213.1 - 9.3e-06 25.6 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EMR73213.1 - 0.00075 18.9 0.0 0.0009 18.6 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EMR73213.1 - 0.0013 18.3 0.1 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EMR73213.1 - 0.0015 19.0 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMR73213.1 - 0.0037 16.9 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR73213.1 - 0.0052 16.1 0.0 0.0061 15.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMR73213.1 - 0.0067 16.1 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR73213.1 - 0.01 14.8 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 EMR73213.1 - 0.019 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 EMR73213.1 - 0.021 15.2 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EMR73213.1 - 0.023 13.7 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EMR73213.1 - 0.036 13.1 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EMR73213.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase N6_N4_Mtase PF01555.13 EMR73213.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Rubrerythrin PF02915.12 EMR73214.1 - 0.00091 19.5 2.5 0.0099 16.2 1.6 2.2 1 1 0 1 1 1 1 Rubrerythrin DUF123 PF01986.11 EMR73215.1 - 6.5e-30 103.1 0.2 8.2e-30 102.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF123 GIY-YIG PF01541.19 EMR73215.1 - 0.00024 21.3 0.2 0.0004 20.7 0.1 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF131 PF01998.12 EMR73217.1 - 0.00021 20.5 1.9 0.00029 20.1 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF131 DUF2628 PF10947.3 EMR73217.1 - 0.038 13.7 0.9 0.038 13.7 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) TerY-C PF15616.1 EMR73218.1 - 0.0037 17.1 4.8 0.0076 16.1 3.4 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-B_box PF00643.19 EMR73218.1 - 0.026 14.4 6.4 0.026 14.4 4.4 1.6 1 1 0 1 1 1 0 B-box zinc finger HSP20 PF00011.16 EMR73218.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Hsp20/alpha crystallin family PGPGW PF09656.5 EMR73218.1 - 0.088 12.1 0.3 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) zf-C3HC4_2 PF13923.1 EMR73218.1 - 0.57 10.2 9.5 2.1 8.4 6.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_2 PF14445.1 EMR73218.1 - 0.83 9.6 6.7 1.5 8.7 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-HIT PF04438.11 EMR73218.1 - 1.1 8.9 10.8 6.1 6.5 7.4 2.1 1 1 0 1 1 1 0 HIT zinc finger zf-C2HC5 PF06221.8 EMR73218.1 - 5.8 6.7 11.3 21 4.9 7.8 1.8 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.1 EMR73218.1 - 6.7 6.0 6.2 2.2 7.5 1.5 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Lactamase_B PF00753.22 EMR73219.1 - 2.6e-31 108.8 0.3 3.1e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR73219.1 - 2.7e-09 36.8 0.1 3.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_elim_lyase PF01212.16 EMR73220.1 - 8.9e-88 294.1 0.1 1.1e-87 293.9 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMR73220.1 - 1.6e-06 27.4 0.0 0.00027 20.1 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EMR73220.1 - 0.00021 20.3 0.0 0.00053 19.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMR73220.1 - 0.0032 15.8 0.1 0.0058 14.9 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.14 EMR73220.1 - 0.068 11.5 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydroxymethyltransferase DUF1931 PF09123.6 EMR73220.1 - 0.087 12.7 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) Ldh_2 PF02615.9 EMR73221.1 - 6.9e-85 284.7 0.0 7.7e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase FAD_binding_2 PF00890.19 EMR73222.1 - 7.4e-92 308.3 0.2 9.7e-92 307.9 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMR73222.1 - 6.5e-23 80.9 0.2 1.3e-22 80.0 0.1 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EMR73222.1 - 9.3e-08 32.1 1.4 3.6e-05 23.7 1.0 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR73222.1 - 9.8e-06 24.6 2.9 9.8e-05 21.4 0.7 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EMR73222.1 - 0.0073 15.2 1.1 0.91 8.3 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 EMR73222.1 - 0.024 15.0 0.1 0.54 10.6 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR73222.1 - 0.028 14.4 0.2 0.071 13.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR73222.1 - 0.14 11.2 1.3 0.44 9.5 0.9 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase D-aminoacyl_C PF07908.7 EMR73223.1 - 2.3e-17 61.9 0.1 4.8e-17 60.9 0.1 1.6 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Amidohydro_3 PF07969.6 EMR73223.1 - 8.2e-09 35.1 0.5 1.7e-08 34.1 0.3 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR73223.1 - 1.6e-08 34.8 0.0 3.5e-06 27.2 0.0 2.6 1 1 2 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EMR73223.1 - 0.001 18.7 0.0 0.0045 16.6 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family UPF0542 PF15086.1 EMR73229.1 - 2.1 8.1 4.8 4.4 7.1 1.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF70 PF01901.11 EMR73230.1 - 3.3 6.6 14.1 4.7 6.1 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF70 OsmC PF02566.14 EMR73242.1 - 3.4e-11 43.2 0.0 5.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein DUF35_N PF12172.3 EMR73243.1 - 0.00026 20.7 1.4 0.00039 20.2 0.9 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) NOB1_Zn_bind PF08772.6 EMR73243.1 - 0.00055 19.7 0.5 0.00058 19.6 0.4 1.1 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.5 EMR73243.1 - 0.00068 19.5 8.0 0.013 15.4 5.5 2.1 1 1 0 1 1 1 1 Zinc ribbon domain HypA PF01155.14 EMR73243.1 - 0.0016 18.0 0.5 0.0016 18.0 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EMR73243.1 - 0.0021 17.8 2.2 0.0024 17.6 1.5 1.1 1 0 0 1 1 1 1 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EMR73243.1 - 0.0033 16.7 5.3 0.12 11.6 0.2 2.1 1 1 1 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EMR73243.1 - 0.0061 15.7 6.5 0.0088 15.2 4.5 1.3 1 1 0 1 1 1 1 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 EMR73243.1 - 0.0071 15.8 0.4 0.0079 15.6 0.3 1.2 1 0 0 1 1 1 1 Transposase zinc-binding domain TFIIS_C PF01096.13 EMR73243.1 - 0.0072 15.9 1.5 1.1 9.0 0.1 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EMR73243.1 - 0.0076 16.0 4.8 0.057 13.2 0.3 2.1 1 1 1 2 2 2 1 Transposase zinc-ribbon domain DUF1610 PF07754.6 EMR73243.1 - 0.0089 16.1 7.6 0.63 10.2 1.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1610) Prok-RING_1 PF14446.1 EMR73243.1 - 0.01 15.5 2.1 0.013 15.1 1.5 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.21 EMR73243.1 - 0.011 16.0 1.3 1.2 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C4_Topoisom PF01396.14 EMR73243.1 - 0.016 14.7 1.6 0.46 10.0 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-ISL3 PF14690.1 EMR73243.1 - 0.021 14.8 1.2 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C4pol PF14260.1 EMR73243.1 - 0.021 14.8 0.2 0.023 14.6 0.2 1.1 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zinc_ribbon_4 PF13717.1 EMR73243.1 - 0.031 13.9 2.1 1 9.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMR73243.1 - 0.038 13.5 2.7 0.88 9.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.9 EMR73243.1 - 0.048 13.3 3.2 2.6 7.7 2.2 2.2 1 1 0 1 1 1 0 Adenylate kinase, active site lid Ribosomal_L37e PF01907.14 EMR73243.1 - 0.055 13.2 0.2 0.065 13.0 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L37e Desulfoferrod_N PF06397.7 EMR73243.1 - 0.064 12.6 2.2 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-NADH-PPase PF09297.6 EMR73243.1 - 0.065 12.7 1.7 1 8.9 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.4 EMR73243.1 - 0.074 12.7 6.2 1.6 8.5 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ribosomal_L32p PF01783.18 EMR73243.1 - 0.081 13.1 0.1 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L32p protein family Opy2 PF09463.5 EMR73243.1 - 0.099 12.7 0.7 0.59 10.2 0.1 1.9 2 0 0 2 2 2 0 Opy2 protein DUF2072 PF09845.4 EMR73243.1 - 0.11 12.4 0.6 0.11 12.4 0.4 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NMD3 PF04981.8 EMR73243.1 - 0.13 11.3 0.8 0.13 11.3 0.5 1.0 1 0 0 1 1 1 0 NMD3 family OrfB_Zn_ribbon PF07282.6 EMR73243.1 - 0.2 11.3 2.6 8.2 6.1 0.1 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_3 PF13920.1 EMR73243.1 - 0.21 11.3 1.5 0.25 11.0 1.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CpXC PF14353.1 EMR73243.1 - 0.29 11.1 2.8 10 6.1 0.1 2.0 1 1 1 2 2 2 0 CpXC protein RRN7 PF11781.3 EMR73243.1 - 0.35 10.4 4.9 2.1 7.8 0.4 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-AN1 PF01428.11 EMR73243.1 - 0.41 10.5 2.8 1.6 8.6 0.2 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger Auto_anti-p27 PF06677.7 EMR73243.1 - 0.48 10.2 5.5 0.99 9.2 2.7 2.1 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rubredoxin PF00301.15 EMR73243.1 - 0.62 9.9 5.0 2.9 7.8 0.6 2.1 1 1 1 2 2 2 0 Rubredoxin zinc_ribbon_2 PF13240.1 EMR73243.1 - 0.83 9.2 7.0 6.4 6.3 4.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EMR73243.1 - 0.98 9.1 4.2 7.4 6.3 0.4 2.2 1 1 2 3 3 3 0 Nudix N-terminal A2L_zn_ribbon PF08792.5 EMR73243.1 - 0.98 8.9 3.1 3.5 7.2 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FPG_IleRS PF06827.9 EMR73243.1 - 1 9.0 4.2 4.9 6.8 3.0 1.9 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS zf-dskA_traR PF01258.12 EMR73243.1 - 1 9.1 8.5 3.9 7.3 0.4 2.1 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-HIT PF04438.11 EMR73243.1 - 1.1 8.9 4.0 3 7.5 2.7 1.6 1 1 0 1 1 1 0 HIT zinc finger C1_3 PF07649.7 EMR73243.1 - 1.2 9.2 3.5 2.5 8.2 2.3 1.7 1 1 0 1 1 1 0 C1-like domain zf-H2C2_2 PF13465.1 EMR73243.1 - 1.4 9.3 7.1 1.6 9.1 0.3 2.2 1 1 1 2 2 2 0 Zinc-finger double domain YhfH PF14149.1 EMR73243.1 - 2 8.2 8.6 1.1 9.0 0.7 2.2 1 1 1 2 2 2 0 YhfH-like protein PhnA_Zn_Ribbon PF08274.7 EMR73243.1 - 5.9 6.7 6.1 92 2.9 4.2 2.1 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-tcix PF14952.1 EMR73243.1 - 6.6 6.1 6.5 11 5.4 1.4 2.1 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF1819 PF08849.6 EMR73245.1 - 1.4e-16 60.4 1.6 4e-16 58.9 0.4 1.9 1 1 1 2 2 2 1 Putative inner membrane protein (DUF1819) DUF1132 PF06575.7 EMR73245.1 - 0.013 15.7 0.6 0.044 14.0 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) DUF3970 PF13113.1 EMR73245.1 - 0.048 13.3 0.1 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) DUF1788 PF08747.6 EMR73246.1 - 3.8e-05 23.5 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1788) Sigma54_activ_2 PF14532.1 EMR73247.1 - 0.036 14.1 0.0 7.7 6.5 0.0 3.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 EMR73247.1 - 0.057 14.2 0.0 5.6 7.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain Zot PF05707.7 EMR73247.1 - 0.066 12.6 0.7 0.18 11.2 0.1 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Methyltransf_32 PF13679.1 EMR73247.1 - 0.19 11.4 0.0 0.55 9.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EMR73248.1 - 1.4e-17 63.8 0.0 4.4e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMR73248.1 - 9.2e-08 31.8 0.9 0.00022 20.8 0.0 3.1 3 1 0 3 3 3 2 Putative RNA methylase family UPF0020 Eco57I PF07669.6 EMR73248.1 - 4.9e-07 30.0 0.5 5.1e-06 26.8 0.1 2.9 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Methyltransf_31 PF13847.1 EMR73248.1 - 0.015 14.8 7.7 0.049 13.2 0.0 4.1 5 0 0 5 5 5 0 Methyltransferase domain MTS PF05175.9 EMR73248.1 - 0.026 13.8 0.0 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain NfI_DNAbd_pre-N PF10524.4 EMR73248.1 - 0.05 13.2 1.7 0.064 12.8 0.0 2.0 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus PglZ PF08665.7 EMR73249.1 - 6.2e-08 32.5 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 PglZ domain Lon_2 PF13337.1 EMR73251.1 - 9.9e-73 245.0 0.0 1.1e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease Hydantoinase_B PF02538.9 EMR73253.1 - 8.4e-14 50.6 0.0 9.5e-14 50.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Pyrophosphatase PF00719.14 EMR73254.1 - 1.8e-46 157.3 0.1 2.1e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase TatD_DNase PF01026.16 EMR73256.1 - 1.3e-47 162.1 0.0 1.6e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Phage_Gp23 PF10669.4 EMR73257.1 - 0.092 12.8 0.1 0.094 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) POR PF01558.13 EMR73259.1 - 1.3e-35 122.8 0.2 1.6e-35 122.5 0.1 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.16 EMR73260.1 - 2.4e-25 88.8 1.2 3.8e-25 88.2 0.9 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 EMR73260.1 - 4.7e-10 38.6 17.1 2.2e-08 33.3 1.8 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.1 EMR73260.1 - 4.3e-08 32.8 8.5 9.4e-08 31.7 5.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMR73260.1 - 1.3e-07 31.1 15.5 0.0001 22.0 1.9 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 EMR73260.1 - 1.1e-06 28.7 7.9 1.1e-06 28.7 5.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EMR73260.1 - 4.4e-06 26.4 19.7 1.7e-05 24.5 7.6 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 EMR73260.1 - 6.1e-06 25.8 16.2 2.1e-05 24.1 1.5 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.2 EMR73260.1 - 7.1e-06 26.3 14.2 8.5e-06 26.0 7.1 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMR73260.1 - 3.4e-05 23.7 9.6 4.3e-05 23.4 5.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 EMR73260.1 - 0.00089 19.7 13.9 0.047 14.2 2.0 3.2 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_16 PF13484.1 EMR73260.1 - 0.0014 19.3 7.0 0.0027 18.4 1.3 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Transketolase_C PF02780.15 EMR73260.1 - 0.0032 17.4 0.0 0.009 15.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Fer4_17 PF13534.1 EMR73260.1 - 0.0036 17.6 11.7 0.33 11.3 6.3 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.2 EMR73260.1 - 0.004 17.3 3.5 0.004 17.3 2.4 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain DUF1302 PF06980.6 EMR73260.1 - 0.23 9.9 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Fer4_13 PF13370.1 EMR73260.1 - 0.54 10.6 13.0 1.3 9.4 2.1 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_18 PF13746.1 EMR73260.1 - 1.4 9.4 18.8 0.11 12.9 3.1 3.2 3 1 1 4 4 3 0 4Fe-4S dicluster domain GFO_IDH_MocA PF01408.17 EMR73265.1 - 1.4e-09 38.5 0.0 1.5e-09 38.4 0.0 1.0 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold E3_binding PF02817.12 EMR73265.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 e3 binding domain URO-D PF01208.12 EMR73266.1 - 9.5e-30 103.6 0.1 3e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) B12-binding PF02310.14 EMR73267.1 - 4e-23 81.5 0.3 5.5e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.12 EMR73267.1 - 1.6e-08 34.4 0.1 5.5e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 B12 binding domain DUF4137 PF13593.1 EMR73268.1 - 0.023 13.8 1.1 0.028 13.5 0.8 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) SpoVAB PF13782.1 EMR73268.1 - 0.075 13.0 1.3 0.087 12.8 0.4 1.5 1 1 0 1 1 1 0 Stage V sporulation protein AB Herpes_LMP1 PF05297.6 EMR73268.1 - 1.4 7.7 7.2 1.6 7.5 5.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PEP_mutase PF13714.1 EMR73269.1 - 1.3e-57 194.7 1.3 1.5e-57 194.5 0.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMR73269.1 - 7.4e-17 60.7 1.5 1e-16 60.3 1.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF998 PF06197.8 EMR73271.1 - 3e-22 78.8 13.7 3.6e-22 78.5 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF998) MerC PF03203.9 EMR73271.1 - 0.023 15.0 2.3 0.023 15.0 1.6 2.5 1 1 2 3 3 3 0 MerC mercury resistance protein MFS_2 PF13347.1 EMR73271.1 - 0.39 9.0 11.5 0.05 11.9 4.0 2.1 1 1 1 2 2 2 0 MFS/sugar transport protein Tetraspannin PF00335.15 EMR73271.1 - 4.2 6.5 13.0 0.035 13.3 1.5 2.4 1 1 1 2 2 2 0 Tetraspanin family MFS_1 PF07690.11 EMR73271.1 - 8.5 4.9 21.9 4 6.0 10.6 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 EMR73272.1 - 0.011 14.7 0.1 0.36 9.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 DUF377 PF04041.8 EMR73272.1 - 0.14 10.8 0.5 0.78 8.3 0.0 2.2 3 1 0 3 3 3 0 Domain of unknown function (DUF377) DNAPolymera_Pol PF11590.3 EMR73281.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol GrpB PF04229.9 EMR73282.1 - 3.3e-40 137.5 0.0 3.7e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Thia_YuaJ PF09515.5 EMR73289.1 - 1.2e-29 103.3 9.5 2.1e-29 102.5 6.6 1.4 1 1 0 1 1 1 1 Thiamine transporter protein (Thia_YuaJ) CarboxypepD_reg PF13620.1 EMR73290.1 - 0.00064 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMR73290.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4480) Dioxygenase_C PF00775.16 EMR73290.1 - 0.025 13.8 0.0 0.05 12.8 0.0 1.5 1 1 0 1 1 1 0 Dioxygenase MFS_1 PF07690.11 EMR73302.1 - 1.6e-28 99.4 88.3 2e-16 59.6 21.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EMR73302.1 - 2.7e-15 55.6 23.7 2.7e-15 55.6 16.4 1.7 1 1 1 2 2 2 1 MFS/sugar transport protein BT1 PF03092.11 EMR73302.1 - 3.1e-07 29.4 18.0 3.2e-05 22.8 12.5 3.0 1 1 0 1 1 1 1 BT1 family Amidase PF01425.16 EMR73312.1 - 3e-09 36.2 0.0 3.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Amidase HTH_45 PF14947.1 EMR73313.1 - 1e-14 54.1 0.1 1.2e-14 53.8 0.1 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 EMR73313.1 - 0.067 12.9 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Bactofilin PF04519.8 EMR73314.1 - 2.3e-08 33.9 0.7 0.0021 18.0 0.0 2.9 1 1 1 2 2 2 2 Polymer-forming cytoskeletal Response_reg PF00072.19 EMR73321.1 - 0.0013 18.6 0.1 0.0017 18.3 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain DUF724 PF05266.9 EMR73321.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EmrE PF13536.1 EMR73323.1 - 0.043 14.0 7.4 0.051 13.7 5.1 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Nitroreductase PF00881.19 EMR73327.1 - 9.5e-08 32.0 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF1616 PF07760.6 EMR73345.1 - 2.1e-31 109.1 10.9 3.5e-31 108.4 7.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) HTH_11 PF08279.7 EMR73345.1 - 0.21 11.2 0.9 0.71 9.5 0.1 2.2 2 0 0 2 2 2 0 HTH domain YesK PF14150.1 EMR73345.1 - 4.1 7.5 9.6 14 5.8 2.1 2.7 2 1 0 2 2 2 0 YesK-like protein Exosortase_EpsH PF09721.5 EMR73346.1 - 2.7e-40 138.2 23.5 2.7e-40 138.2 16.3 1.6 2 0 0 2 2 2 1 Transmembrane exosortase (Exosortase_EpsH) CRISPR_Cas2 PF09827.4 EMR73347.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 CRISPR associated protein Cas2 Lactamase_B PF00753.22 EMR73348.1 - 5.6e-13 48.9 4.1 5.8e-12 45.6 2.9 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR73348.1 - 0.00043 19.8 0.4 0.00067 19.2 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR73348.1 - 0.093 12.4 0.5 0.43 10.2 0.1 2.1 1 1 0 2 2 2 0 Beta-lactamase superfamily domain Methyltransf_11 PF08241.7 EMR73349.1 - 4.1e-10 40.0 0.0 5.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73349.1 - 1.1e-06 28.2 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR73349.1 - 1.3e-05 25.6 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR73349.1 - 3.4e-05 24.3 0.0 4.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR73349.1 - 4e-05 22.8 0.0 4.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMR73349.1 - 0.00036 20.5 0.0 0.00042 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR73349.1 - 0.00038 20.7 0.0 0.00054 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR73349.1 - 0.0005 19.8 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR73349.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMR73349.1 - 0.049 13.1 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EMR73349.1 - 0.057 12.4 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Fibrillarin PF01269.12 EMR73349.1 - 0.058 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin PrmA PF06325.8 EMR73349.1 - 0.083 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA-synt_1c_C PF03950.13 EMR73350.1 - 1.2e-28 99.9 0.0 1.7e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L7Ae PF01248.21 EMR73351.1 - 2.4e-28 97.5 0.1 2.9e-28 97.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 EMR73351.1 - 0.015 15.3 0.3 4.2 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) PELOTA_1 PF15608.1 EMR73351.1 - 0.045 13.5 0.1 0.062 13.0 0.1 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Ribosomal_S28e PF01200.13 EMR73352.1 - 1e-27 95.6 4.8 1.1e-27 95.5 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e NDK PF00334.14 EMR73353.1 - 1.3e-33 115.6 0.0 4.7e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Nucleoside diphosphate kinase ATP-synt_DE PF00401.15 EMR73353.1 - 0.17 11.7 0.9 0.34 10.8 0.1 1.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ECF-ribofla_trS PF07155.7 EMR73354.1 - 4.2e-34 117.6 21.1 4.8e-34 117.5 14.6 1.0 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component DUF3816 PF12822.2 EMR73354.1 - 5.3e-05 23.1 20.4 6.9e-05 22.7 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) 5TM-5TMR_LYT PF07694.7 EMR73354.1 - 0.021 14.1 18.9 0.026 13.8 13.1 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT PALP PF00291.20 EMR73355.1 - 1.6e-58 198.3 0.0 2e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PadR PF03551.9 EMR73355.1 - 3e-06 26.9 0.3 7.4e-06 25.6 0.2 1.7 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.1 EMR73355.1 - 0.0055 16.4 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DUF4364 PF14277.1 EMR73355.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) tRNA_anti-codon PF01336.20 EMR73356.1 - 4.1e-05 23.3 0.1 5.2e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF3127 PF11325.3 EMR73356.1 - 0.087 12.8 0.2 0.21 11.6 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3127) LSM PF01423.17 EMR73357.1 - 4.4e-18 64.5 0.3 5.2e-18 64.3 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMR73357.1 - 0.025 14.5 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Methyltransf_11 PF08241.7 EMR73358.1 - 3.3e-11 43.5 0.0 7.8e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73358.1 - 1.4e-10 40.9 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR73358.1 - 1.3e-08 35.0 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR73358.1 - 8e-06 25.1 0.0 9.8e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR73358.1 - 5e-05 23.7 0.0 9.8e-05 22.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR73358.1 - 0.00016 22.2 0.0 0.00034 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR73358.1 - 0.00064 19.4 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR73358.1 - 0.0033 16.5 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 EMR73358.1 - 0.0067 15.4 0.0 0.0078 15.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EMR73358.1 - 0.01 15.2 0.1 0.017 14.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.6 EMR73358.1 - 0.057 12.1 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EMR73358.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ILVD_EDD PF00920.16 EMR73360.1 - 1.2e-194 647.6 6.5 1.4e-194 647.4 4.5 1.0 1 0 0 1 1 1 1 Dehydratase family HMGL-like PF00682.14 EMR73364.1 - 2.7e-32 112.3 0.0 3.4e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Creatininase PF02633.9 EMR73366.1 - 2.8e-54 183.7 0.0 3.1e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Cpn60_TCP1 PF00118.19 EMR73367.1 - 3e-168 560.4 10.1 3.5e-168 560.2 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 EMR73367.1 - 0.083 12.7 0.2 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) DUF3375 PF11855.3 EMR73367.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Cpn60_TCP1 PF00118.19 EMR73368.1 - 3.6e-11 42.3 0.3 3.9e-11 42.2 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NADase_NGA PF07461.6 EMR73383.1 - 0.045 12.4 0.1 0.067 11.8 0.1 1.1 1 0 0 1 1 1 0 Nicotine adenine dinucleotide glycohydrolase (NADase) DUF3189 PF11385.3 EMR73383.1 - 0.056 13.0 0.3 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3189) PHP PF02811.14 EMR73384.1 - 1.3e-12 47.8 0.1 1.4e-12 47.7 0.1 1.0 1 0 0 1 1 1 1 PHP domain DUF2129 PF09902.4 EMR73385.1 - 0.11 12.3 0.4 0.17 11.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) Peptidase_M14 PF00246.19 EMR73390.1 - 3.8e-12 46.3 0.0 1.2e-11 44.7 0.0 1.7 2 1 0 2 2 2 1 Zinc carboxypeptidase DUF3812 PF12757.2 EMR73390.1 - 0.15 12.0 1.0 0.27 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) DUF3055 PF11256.3 EMR73391.1 - 0.1 12.7 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3055) zf-Mss51 PF13824.1 EMR73404.1 - 0.0027 17.5 0.3 0.01 15.6 0.2 2.1 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.2 EMR73404.1 - 0.016 14.9 0.5 0.04 13.7 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 EMR73404.1 - 0.051 13.2 4.6 0.1 12.3 3.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 EMR73404.1 - 0.082 12.1 4.8 0.2 10.9 3.3 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMR73404.1 - 6.4 6.4 8.3 1.2e+02 2.2 6.0 2.4 1 1 0 1 1 1 0 zinc-ribbon domain AA_permease_2 PF13520.1 EMR73405.1 - 0.044 12.3 0.1 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease Rax2 PF12768.2 EMR73405.1 - 0.077 12.1 0.8 0.89 8.7 0.0 2.0 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Acetyltransf_9 PF13527.1 EMR73406.1 - 1.6e-14 53.8 0.0 4.9e-14 52.2 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR73406.1 - 0.00072 19.6 0.4 0.036 14.2 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR73406.1 - 0.0011 18.9 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF2649 PF10854.3 EMR73406.1 - 0.062 13.4 0.9 0.17 12.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) FR47 PF08445.5 EMR73406.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein SIR2 PF02146.12 EMR73407.1 - 0.093 12.4 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Sir2 family Abi PF02517.11 EMR73408.1 - 3.7e-12 46.2 10.0 3.7e-12 46.2 6.9 2.5 1 1 1 2 2 2 1 CAAX protease self-immunity DUF1109 PF06532.6 EMR73409.1 - 0.043 13.2 3.4 2.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1109) Cation_ATPase_C PF00689.16 EMR73409.1 - 8.4 5.8 16.2 0.54 9.7 5.7 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus FtsX PF02687.16 EMR73410.1 - 0.035 13.8 0.7 0.037 13.7 0.5 1.1 1 0 0 1 1 1 0 FtsX-like permease family MFS_1 PF07690.11 EMR73426.1 - 3.6e-26 91.7 15.4 3.9e-26 91.5 10.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR73426.1 - 0.0002 21.0 0.0 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 EMR73426.1 - 0.0036 15.9 8.4 0.0048 15.5 5.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 EMR73426.1 - 0.0041 17.1 1.1 0.008 16.1 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1228) Lactamase_B PF00753.22 EMR73432.1 - 1e-24 87.2 0.3 1.3e-24 86.9 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rieske PF00355.21 EMR73433.1 - 1.5e-17 62.8 0.0 1.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EMR73433.1 - 2.3e-09 36.9 0.0 2.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Acetyltransf_9 PF13527.1 EMR73439.1 - 9.4e-06 25.5 0.0 1.1e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Penicillinase_R PF03965.11 EMR73441.1 - 0.0012 18.8 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor TMEM164 PF14808.1 EMR73442.1 - 0.061 12.5 0.4 0.069 12.3 0.3 1.1 1 0 0 1 1 1 0 TMEM164 family SyrA PF11089.3 EMR73442.1 - 0.17 11.6 0.3 0.17 11.6 0.2 2.3 3 0 0 3 3 3 0 Exopolysaccharide production repressor DUF3188 PF11384.3 EMR73442.1 - 0.49 10.0 3.4 8.9 5.9 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3188) Acetyltransf_3 PF13302.1 EMR73443.1 - 1e-08 35.4 0.0 1.4e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain CDI PF02234.14 EMR73443.1 - 0.0091 15.7 0.1 0.025 14.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Polysacc_synt PF01943.12 EMR73446.1 - 0.16 11.2 0.9 0.15 11.2 0.6 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PadR PF03551.9 EMR73447.1 - 4.4e-17 61.6 0.2 5.9e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.17 EMR73447.1 - 0.011 15.4 0.3 0.026 14.2 0.2 1.7 1 1 0 1 1 1 0 MarR family MarR_2 PF12802.2 EMR73447.1 - 0.097 12.3 0.3 0.19 11.3 0.2 1.7 1 1 0 1 1 1 0 MarR family Baculo_LEF5_C PF11792.3 EMR73447.1 - 0.17 11.3 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain ABC_tran PF00005.22 EMR73448.1 - 4.7e-30 104.6 0.0 1.6e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EMR73448.1 - 2.2e-16 60.7 0.0 1.5e-11 44.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EMR73448.1 - 0.0012 18.0 0.2 0.43 9.7 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR73448.1 - 0.002 18.4 5.2 0.022 15.0 3.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 EMR73448.1 - 0.0029 16.1 0.4 1.6 7.0 0.0 2.7 2 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMR73448.1 - 0.0055 16.2 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EMR73448.1 - 0.01 14.9 0.0 0.061 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMR73448.1 - 0.014 15.3 1.4 0.39 10.6 1.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EMR73448.1 - 0.047 13.1 0.1 1.8 7.9 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain ABC2_membrane PF01061.19 EMR73449.1 - 1e-19 70.5 17.3 1e-19 70.5 12.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EMR73449.1 - 2.5e-11 43.2 25.0 2.5e-11 43.2 17.3 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 EMR73449.1 - 5.7e-06 25.3 15.3 6.5e-06 25.2 10.1 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein TMEM190 PF15431.1 EMR73450.1 - 0.032 14.1 0.1 0.032 14.1 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 Rubrerythrin PF02915.12 EMR73451.1 - 9e-07 29.2 0.8 1.2e-06 28.9 0.6 1.2 1 0 0 1 1 1 1 Rubrerythrin DUF2202 PF09968.4 EMR73451.1 - 0.015 14.9 0.2 0.018 14.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Ferritin PF00210.19 EMR73451.1 - 0.037 13.7 0.8 0.057 13.1 0.6 1.5 1 1 0 1 1 1 0 Ferritin-like domain COQ7 PF03232.8 EMR73451.1 - 0.04 13.4 0.2 0.05 13.0 0.2 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 PTS_EIIA_2 PF00359.17 EMR73451.1 - 0.091 12.4 0.1 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF2383 PF09537.5 EMR73451.1 - 0.11 12.7 0.4 0.23 11.7 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) zf-ribbon_3 PF13248.1 EMR73452.1 - 0.00066 18.7 1.9 0.0013 17.9 1.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EMR73452.1 - 0.0047 16.7 0.3 0.0082 15.9 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EMR73452.1 - 0.012 15.1 3.8 0.031 13.7 2.6 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-B_box PF00643.19 EMR73452.1 - 0.044 13.6 0.6 0.063 13.1 0.4 1.2 1 0 0 1 1 1 0 B-box zinc finger zinc-ribbons_6 PF07191.7 EMR73452.1 - 0.086 12.6 0.3 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-Mss51 PF13824.1 EMR73452.1 - 0.15 11.9 0.7 0.25 11.2 0.5 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 UPF0547 PF10571.4 EMR73452.1 - 0.88 9.3 3.8 2.3 8.0 2.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 PGK PF00162.14 EMR73456.1 - 2.8e-22 78.7 0.0 3.1e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Homoserine_dh PF00742.14 EMR73457.1 - 7.2e-20 71.4 0.0 7.9e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EMR73458.1 - 0.019 15.3 0.0 0.021 15.2 0.0 1.1 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CARDB PF07705.6 EMR73473.1 - 0.083 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 CARDB Seipin PF06775.9 EMR73475.1 - 0.021 14.3 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) Metalloenzyme PF01676.13 EMR73481.1 - 0.018 14.4 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Metalloenzyme superfamily DisA_N PF02457.11 EMR73481.1 - 0.03 13.4 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding STAT2_C PF12188.3 EMR73481.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal Glycos_transf_1 PF00534.15 EMR73482.1 - 3.5e-38 130.7 0.2 5e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR73482.1 - 5.8e-18 65.3 0.0 9.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMR73482.1 - 8.4e-09 35.5 0.0 1.9e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EMR73482.1 - 7.6e-06 25.8 2.0 2.1e-05 24.3 1.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_4 PF13439.1 EMR73482.1 - 0.0012 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EMR73482.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF4150 PF13665.1 EMR73485.1 - 2.1e-14 53.3 0.3 5.8e-14 51.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4150) DUF1664 PF07889.7 EMR73485.1 - 0.071 12.9 2.6 0.12 12.2 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EMR73485.1 - 0.11 12.3 6.9 0.26 11.0 4.8 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 EMR73485.1 - 3.2 8.1 6.8 1.7 9.1 0.8 2.6 2 0 0 2 2 2 0 SlyX Exo70 PF03081.10 EMR73487.1 - 0.052 12.3 0.2 0.071 11.8 0.1 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit DUF1662 PF07878.6 EMR73519.1 - 0.00021 20.9 1.0 0.0039 16.8 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1662) Gemin6 PF06372.7 EMR73519.1 - 0.0039 16.5 1.1 0.007 15.7 0.2 1.7 2 0 0 2 2 2 1 Gemin6 protein IFT20 PF14931.1 EMR73519.1 - 0.11 12.3 3.6 0.17 11.7 2.5 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 TBPIP PF07106.8 EMR73519.1 - 0.15 11.5 8.4 0.56 9.7 0.8 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF643 PF04867.7 EMR73519.1 - 0.2 12.0 4.0 0.74 10.2 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF643) TSC22 PF01166.13 EMR73519.1 - 0.25 11.3 2.7 0.31 11.0 0.5 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family HTH_19 PF12844.2 EMR73519.1 - 2.6 8.1 7.1 1.4 9.0 0.3 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Fib_alpha PF08702.5 EMR73519.1 - 3 7.9 8.0 0.82 9.7 2.9 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_M50 PF02163.17 EMR73521.1 - 0.2 10.5 1.3 0.31 9.9 0.3 1.9 1 1 1 2 2 2 0 Peptidase family M50 TP6A_N PF04406.9 EMR73524.1 - 8.6e-16 57.3 0.1 1.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EMR73524.1 - 0.00015 21.6 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) FAD_binding_3 PF01494.14 EMR73533.1 - 1.3e-06 27.7 0.2 2.7e-05 23.3 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR73533.1 - 4.6e-06 25.7 1.8 4.8e-05 22.4 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FdhD-NarQ PF02634.10 EMR73534.1 - 9.1e-70 234.7 0.5 1e-69 234.5 0.4 1.0 1 0 0 1 1 1 1 FdhD/NarQ family TF_Zn_Ribbon PF08271.7 EMR73535.1 - 0.001 18.3 1.4 0.0029 16.8 1.0 1.7 1 1 0 1 1 1 1 TFIIB zinc-binding DZR PF12773.2 EMR73535.1 - 0.018 14.8 0.1 0.028 14.2 0.0 1.3 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 EMR73535.1 - 0.074 12.5 0.2 0.15 11.6 0.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S27 Lar_restr_allev PF14354.1 EMR73535.1 - 0.077 13.3 0.9 1.9 8.8 0.6 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Mu-like_Com PF10122.4 EMR73535.1 - 0.081 11.9 0.7 0.14 11.2 0.1 1.7 2 0 0 2 2 2 0 Mu-like prophage protein Com YhfH PF14149.1 EMR73535.1 - 0.094 12.5 1.8 2.7 7.8 0.3 2.1 2 0 0 2 2 2 0 YhfH-like protein COX5B PF01215.14 EMR73535.1 - 0.15 11.7 0.9 0.28 10.8 0.6 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase subunit Vb NTP_transferase PF00483.18 EMR73544.1 - 1.3e-24 86.9 0.0 1.5e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EMR73544.1 - 2.6e-11 43.8 0.0 3e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EMR73544.1 - 0.00058 19.4 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Phage_integrase PF00589.17 EMR73546.1 - 4.4e-06 26.4 0.0 6.3e-05 22.7 0.0 2.4 1 1 0 2 2 2 1 Phage integrase family HD PF01966.17 EMR73547.1 - 1.3e-16 60.6 0.2 2e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 EMR73547.1 - 0.00034 19.9 0.0 0.27 10.4 0.0 2.1 1 1 1 2 2 2 2 HDOD domain Acetate_kinase PF00871.12 EMR73547.1 - 0.012 14.1 0.0 0.016 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetokinase family TFIIE_alpha PF02002.12 EMR73548.1 - 4.6e-18 64.6 1.3 5.8e-18 64.3 0.9 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit Rrf2 PF02082.15 EMR73548.1 - 0.00092 19.2 1.0 0.0013 18.8 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulator Rad50_zn_hook PF04423.9 EMR73548.1 - 0.0064 15.9 0.8 0.19 11.2 0.1 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif Sulfolobus_pRN PF05584.6 EMR73548.1 - 0.0065 16.4 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Sulfolobus plasmid regulatory protein SLT_beta PF02258.11 EMR73548.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Shiga-like toxin beta subunit HTH_9 PF08221.6 EMR73548.1 - 0.03 14.1 0.1 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF842 PF05811.8 EMR73548.1 - 0.048 13.1 0.1 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DNA_ligase_ZBD PF03119.11 EMR73548.1 - 0.076 12.7 1.2 0.076 12.7 0.9 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Trm56 PF01994.11 EMR73549.1 - 5.9e-45 151.9 0.0 7.4e-45 151.6 0.0 1.1 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 bPH_5 PF10882.3 EMR73550.1 - 0.0018 18.0 0.3 0.043 13.6 0.2 2.5 1 1 0 1 1 1 1 Bacterial PH domain TIM PF00121.13 EMR73551.1 - 1.2e-28 99.7 1.5 2.9e-26 92.0 1.1 2.0 1 1 0 1 1 1 1 Triosephosphate isomerase ThiG PF05690.9 EMR73551.1 - 1.3e-05 24.4 1.5 1.6e-05 24.1 0.4 1.7 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.13 EMR73551.1 - 0.00023 20.1 0.4 0.00049 19.0 0.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Synuclein PF01387.12 EMR73551.1 - 0.0024 17.7 1.4 0.0048 16.7 0.7 1.6 2 0 0 2 2 2 1 Synuclein NMO PF03060.10 EMR73551.1 - 0.0047 16.1 0.3 0.0068 15.5 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EMR73551.1 - 0.0071 15.6 0.7 0.019 14.2 0.1 2.0 3 0 0 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 EMR73551.1 - 0.0077 15.3 0.1 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PcrB PF01884.12 EMR73551.1 - 0.032 13.4 0.7 0.068 12.4 0.2 1.7 2 0 0 2 2 2 0 PcrB family Hydrolase_like PF13242.1 EMR73551.1 - 0.055 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like PGM_PMM_I PF02878.11 EMR73552.1 - 2.3e-38 130.7 0.0 5.9e-38 129.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EMR73552.1 - 5.2e-25 87.6 0.0 1.1e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EMR73552.1 - 1.7e-24 86.1 0.1 3.8e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMR73552.1 - 1.2e-12 47.6 0.3 4.8e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Hexapep PF00132.19 EMR73553.1 - 1.1e-22 78.4 34.5 1.5e-06 27.3 0.1 4.1 1 1 5 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMR73553.1 - 4.9e-07 29.2 12.6 3.2e-05 23.3 2.5 3.8 2 2 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EMR73553.1 - 0.0074 15.6 0.0 0.0096 15.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.7 EMR73553.1 - 0.16 10.4 2.6 0.14 10.7 0.4 1.7 1 1 1 2 2 2 0 L-fucokinase Glyoxalase_2 PF12681.2 EMR73583.1 - 7e-16 58.7 0.0 8.2e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EMR73583.1 - 6.6e-13 48.7 0.0 1.1e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMR73583.1 - 0.011 15.7 0.1 0.44 10.5 0.0 2.3 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMR73583.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain Glyco_trans_4_2 PF13477.1 EMR73627.1 - 2e-06 27.6 2.1 2.6e-06 27.2 1.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like Phosphodiest PF01663.17 EMR73628.1 - 3.2e-51 174.7 0.0 4.7e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMR73628.1 - 3.4e-06 26.6 0.2 0.012 14.9 0.1 2.5 2 0 0 2 2 2 2 Metalloenzyme superfamily Sulfatase PF00884.18 EMR73628.1 - 0.0032 16.7 0.0 0.6 9.2 0.0 2.9 3 0 0 3 3 3 1 Sulfatase TFIID_90kDa PF04494.10 EMR73628.1 - 0.0076 16.3 0.8 0.064 13.3 0.2 2.8 3 0 0 3 3 3 1 WD40 associated region in TFIID subunit PglZ PF08665.7 EMR73628.1 - 0.059 13.0 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PglZ domain IZUMO PF15005.1 EMR73628.1 - 0.11 12.5 0.2 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Izumo sperm-egg fusion Trep_Strep PF09605.5 EMR73629.1 - 0.0061 16.2 6.3 0.0074 15.9 4.4 1.1 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) FUN14 PF04930.10 EMR73630.1 - 9.7e-13 48.2 9.9 1.6e-12 47.5 6.9 1.3 1 1 0 1 1 1 1 FUN14 family DUF2534 PF10749.4 EMR73630.1 - 0.062 13.2 1.1 0.11 12.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) DUF2666 PF10869.3 EMR73651.1 - 0.022 14.8 5.9 0.049 13.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) RB_A PF01858.12 EMR73651.1 - 0.049 13.2 1.8 0.17 11.5 1.2 1.9 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain His_kinase PF06580.8 EMR73651.1 - 0.65 9.9 5.6 0.5 10.3 0.8 2.5 2 1 0 2 2 2 0 Histidine kinase Laminin_G_3 PF13385.1 EMR73654.1 - 5.7e-07 29.9 0.1 6.6e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Orthopox_A43R PF06517.6 EMR73654.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A43R protein TctB PF07331.6 EMR73656.1 - 0.03 13.9 0.3 0.032 13.8 0.2 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF1212 PF06738.7 EMR73658.1 - 0.03 13.7 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) FUN14 PF04930.10 EMR73661.1 - 0.029 14.6 0.5 0.043 14.0 0.3 1.4 1 1 0 1 1 1 0 FUN14 family Pyridox_oxidase PF01243.15 EMR73690.1 - 4.5e-08 33.0 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3346 PF11826.3 EMR73691.1 - 0.056 13.2 0.2 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) DHDPS PF00701.17 EMR73692.1 - 1.6e-40 138.5 0.0 1.8e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Oxidored_FMN PF00724.15 EMR73693.1 - 6.7e-28 97.6 0.0 1.1e-25 90.3 0.0 2.4 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF1187 PF06688.6 EMR73693.1 - 0.089 12.9 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) Spt5-NGN PF03439.8 EMR73695.1 - 0.074 12.8 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section YCII PF03795.9 EMR73695.1 - 0.082 13.1 0.0 0.1 12.8 0.0 1.3 1 1 0 1 1 1 0 YCII-related domain Creatininase PF02633.9 EMR73696.1 - 2.6e-57 193.6 0.0 3e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Creatinine amidohydrolase DUF2521 PF10730.4 EMR73696.1 - 0.13 12.0 0.0 0.69 9.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2521) Aminotran_1_2 PF00155.16 EMR73697.1 - 6.9e-49 166.7 0.0 8.6e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMR73697.1 - 3.6e-05 22.2 0.0 5.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMR73697.1 - 5.8e-05 22.0 0.0 0.00015 20.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMR73697.1 - 0.00035 19.8 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase D-aminoacyl_C PF07908.7 EMR73698.1 - 7e-14 50.8 0.0 9.6e-14 50.4 0.0 1.3 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Amidohydro_3 PF07969.6 EMR73698.1 - 0.018 14.2 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family Amidohydro_4 PF13147.1 EMR73698.1 - 0.12 12.4 0.1 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase DUF159 PF02586.9 EMR73700.1 - 0.058 12.9 0.5 0.074 12.5 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised ACR, COG2135 CaM_binding PF07839.6 EMR73700.1 - 0.12 12.5 2.9 0.15 12.3 2.0 1.3 1 0 0 1 1 1 0 Plant calmodulin-binding domain DDE_Tnp_1 PF01609.16 EMR73702.1 - 1.6e-15 57.2 0.0 2.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.6 EMR73702.1 - 7.1e-08 32.2 0.1 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Transposase domain (DUF772) PK_C PF02887.11 EMR73705.1 - 2e-19 69.2 1.3 2.7e-19 68.8 0.9 1.2 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DJ-1_PfpI PF01965.19 EMR73705.1 - 0.0031 16.9 0.2 0.17 11.3 0.0 2.2 1 1 0 2 2 2 2 DJ-1/PfpI family Pab87_oct PF13969.1 EMR73705.1 - 0.14 12.2 0.1 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 Pab87 octamerisation domain GFO_IDH_MocA PF01408.17 EMR73706.1 - 2.7e-24 85.9 0.0 3.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR73706.1 - 5e-06 26.2 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AP_endonuc_2 PF01261.19 EMR73707.1 - 2.1e-20 72.9 0.0 3e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UxuA PF03786.8 EMR73707.1 - 3.3e-05 22.6 0.0 0.00029 19.5 0.0 2.1 1 1 0 1 1 1 1 D-mannonate dehydratase (UxuA) FAD_oxidored PF12831.2 EMR73708.1 - 8.3e-136 453.4 0.0 9.5e-136 453.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMR73708.1 - 5.8e-07 28.8 0.1 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EMR73708.1 - 8.6e-06 24.4 0.0 1.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EMR73708.1 - 0.0023 16.9 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR73708.1 - 0.0057 16.6 0.8 0.018 15.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR73708.1 - 0.026 13.3 0.9 0.048 12.4 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EMR73708.1 - 0.033 14.2 0.4 0.62 10.0 0.3 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR73708.1 - 0.051 12.4 1.3 0.093 11.5 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 EMR73708.1 - 0.091 11.8 0.1 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMR73708.1 - 0.15 12.5 0.5 0.46 10.9 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Oxidored_q6 PF01058.17 EMR73709.1 - 4.9e-27 94.1 0.1 8.5e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.1 EMR73709.1 - 6.3e-23 80.6 5.2 9.8e-23 80.0 1.5 2.2 2 0 0 2 2 2 1 NiFe/NiFeSe hydrogenase small subunit C-terminal NiFeSe_Hases PF00374.14 EMR73710.1 - 2.1e-71 241.2 0.0 3e-51 174.7 0.0 2.2 2 0 0 2 2 2 2 Nickel-dependent hydrogenase Robl_LC7 PF03259.12 EMR73710.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain HycI PF01750.13 EMR73711.1 - 2.4e-17 62.6 0.0 3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease SIR2_2 PF13289.1 EMR73712.1 - 3.6e-08 33.4 2.4 7.7e-07 29.0 0.2 3.1 2 1 0 2 2 2 1 SIR2-like domain FUN14 PF04930.10 EMR73713.1 - 4.2e-06 26.9 5.7 4.6e-06 26.8 4.0 1.0 1 0 0 1 1 1 1 FUN14 family MtrD PF04207.7 EMR73713.1 - 0.15 11.4 2.3 0.15 11.4 1.6 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D TM2 PF05154.11 EMR73713.1 - 0.15 12.2 4.0 0.2 11.9 2.8 1.1 1 0 0 1 1 1 0 TM2 domain Acetyltransf_9 PF13527.1 EMR73716.1 - 3e-08 33.5 0.0 3.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR73716.1 - 0.0018 18.3 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR73716.1 - 0.051 13.7 0.1 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR73716.1 - 0.095 12.7 0.1 0.21 11.6 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PIG-L PF02585.12 EMR73718.1 - 1.2e-24 87.2 0.0 1.6e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF2317 PF10079.4 EMR73719.1 - 8.2e-05 21.4 0.1 0.0035 16.0 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2317) zf-Di19 PF05605.7 EMR73725.1 - 1.1 9.4 3.7 3.4 7.8 1.9 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Fer4_3 PF12798.2 EMR73725.1 - 1.4 9.6 4.3 2.3 9.0 3.0 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain AFOR_N PF02730.10 EMR73726.1 - 1.6e-63 213.7 0.4 1.9e-63 213.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain LytR_C PF13399.1 EMR73726.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator TehB PF03848.9 EMR73731.1 - 2.4e-14 52.9 0.0 2.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 EMR73731.1 - 2.3e-11 43.5 0.0 2.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR73731.1 - 1.2e-10 41.7 0.0 1.5e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR73731.1 - 5.4e-10 39.2 0.0 5.7e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR73731.1 - 3.1e-09 37.3 0.0 3.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EMR73731.1 - 8.4e-07 28.6 0.0 9.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 EMR73731.1 - 2.2e-06 27.1 0.0 2.7e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMR73731.1 - 6.3e-06 26.4 0.0 8.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR73731.1 - 4e-05 24.0 0.0 5.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR73731.1 - 0.00089 18.4 0.0 0.00097 18.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EMR73731.1 - 0.0016 18.4 0.1 0.002 18.1 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR73731.1 - 0.0025 16.8 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase SAM_MT PF04445.8 EMR73731.1 - 0.013 14.6 0.6 0.22 10.6 0.4 2.0 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase FmrO PF07091.6 EMR73731.1 - 0.017 14.0 0.0 0.021 13.8 0.0 1.0 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) N2227 PF07942.7 EMR73731.1 - 0.021 13.7 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein MetW PF07021.7 EMR73731.1 - 0.036 13.4 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EMR73731.1 - 0.048 13.2 0.0 0.075 12.6 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EMR73731.1 - 0.084 12.5 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_1 PF00534.15 EMR73751.1 - 3.6e-44 150.1 0.9 5.6e-44 149.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR73751.1 - 9.3e-21 74.3 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMR73751.1 - 7.3e-08 32.5 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EMR73751.1 - 1.3e-06 27.2 0.4 0.00015 20.4 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Asp_Glu_race PF01177.17 EMR73789.1 - 1.9e-29 103.1 0.0 2.3e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Herpes_UL49_5 PF05702.6 EMR73789.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Sulfatase PF00884.18 EMR73790.1 - 1.6e-49 168.7 0.0 2.9e-49 167.9 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMR73790.1 - 1.1e-20 74.2 0.3 3.2e-18 66.1 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMR73790.1 - 2.5e-06 26.2 0.0 7.6e-06 24.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 EMR73790.1 - 2e-05 23.6 0.0 3.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 EMR73790.1 - 0.022 14.1 0.2 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.7 EMR73790.1 - 0.2 11.3 0.3 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 PglZ domain Amidase PF01425.16 EMR73814.1 - 1.4e-21 76.9 0.0 1e-18 67.4 0.0 2.1 1 1 1 2 2 2 2 Amidase DUF2378 PF09536.5 EMR73814.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) MFS_1 PF07690.11 EMR73815.1 - 5.7e-21 74.6 19.2 6.6e-21 74.3 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR73815.1 - 3.2e-05 22.7 9.7 0.00023 19.9 3.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EMR73815.1 - 0.00012 20.6 9.5 0.00015 20.2 6.6 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_3 PF05977.8 EMR73815.1 - 0.0023 16.1 3.2 0.0027 15.8 2.2 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 EMR73815.1 - 0.011 15.4 4.5 0.013 15.2 0.1 2.9 2 1 0 3 3 3 0 MFS_1 like family ATG22 PF11700.3 EMR73815.1 - 0.037 12.5 13.8 0.044 12.2 9.5 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Cpn60_TCP1 PF00118.19 EMR73818.1 - 6e-148 493.4 5.0 6.8e-148 493.2 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.11 EMR73824.1 - 3.1e-28 98.5 13.7 3.1e-28 98.5 9.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR73824.1 - 0.00024 19.6 15.1 0.00039 18.9 10.4 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 EMR73824.1 - 0.00029 19.5 10.4 0.00038 19.1 7.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.10 EMR73824.1 - 0.0008 18.2 3.4 0.0021 16.8 2.3 1.7 1 1 0 1 1 1 1 PUCC protein ATG22 PF11700.3 EMR73824.1 - 0.0031 16.0 13.9 0.0088 14.5 9.6 1.6 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_3 PF05977.8 EMR73824.1 - 0.0047 15.1 7.3 0.0064 14.6 5.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector HCV_core PF01542.13 EMR73824.1 - 0.34 11.3 2.8 27 5.2 0.2 3.3 3 0 0 3 3 3 0 Hepatitis C virus core protein DUF3784 PF12650.2 EMR73824.1 - 0.51 10.3 0.1 0.51 10.3 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) MMR_HSR1 PF01926.18 EMR73825.1 - 1.4e-18 66.9 0.0 2.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 EMR73825.1 - 3.8e-18 65.3 0.1 7.1e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal FeoB_N PF02421.13 EMR73825.1 - 5.2e-08 32.3 0.1 4.7e-07 29.2 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMR73825.1 - 3.7e-07 29.7 0.0 6.2e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EMR73825.1 - 2.7e-06 27.8 0.0 5.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EMR73825.1 - 0.0013 18.6 0.0 0.027 14.2 0.0 2.6 1 1 1 2 2 2 1 Dynamin family Ras PF00071.17 EMR73825.1 - 0.002 17.5 0.0 0.0079 15.6 0.0 2.0 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 EMR73825.1 - 0.004 16.3 0.0 0.0069 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HhH-GPD PF00730.20 EMR73826.1 - 2.9e-20 72.5 0.0 3.6e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.4 EMR73826.1 - 1.4e-05 25.0 3.0 2.5e-05 24.2 2.1 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 EMR73826.1 - 0.00012 21.6 1.2 0.0018 17.8 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EMR73826.1 - 0.024 14.7 0.2 0.13 12.4 0.2 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix domain DUF2400 PF09674.5 EMR73826.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Ribosomal_L3 PF00297.17 EMR73827.1 - 7.8e-74 248.3 0.3 9.1e-74 248.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L4 PF00573.17 EMR73828.1 - 2.2e-40 138.1 0.1 2.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.15 EMR73829.1 - 6.1e-20 70.9 1.4 2.2e-19 69.1 1.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 TusA PF01206.12 EMR73829.1 - 0.12 11.9 0.3 0.25 10.9 0.1 1.6 1 1 0 2 2 2 0 Sulfurtransferase TusA Ribosomal_L2_C PF03947.13 EMR73830.1 - 5.2e-35 120.0 2.9 7.2e-35 119.6 2.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMR73830.1 - 3.1e-05 23.8 0.0 0.00029 20.7 0.0 2.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S19 PF00203.16 EMR73831.1 - 2.5e-21 75.0 0.3 3.7e-21 74.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 DUF668 PF05003.7 EMR73831.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF668) Ribosomal_L22 PF00237.14 EMR73832.1 - 5.5e-29 100.1 0.1 7e-29 99.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.15 EMR73833.1 - 6.8e-14 51.8 0.1 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EMR73833.1 - 1.9e-09 36.9 0.0 4.3e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 KH domain CARDB PF07705.6 EMR73834.1 - 0.0014 18.6 1.6 0.069 13.2 0.0 3.6 3 2 1 4 4 4 1 CARDB Transglut_C PF00927.17 EMR73834.1 - 0.052 13.6 0.0 52 3.9 0.0 3.2 3 0 0 3 3 3 0 Transglutaminase family, C-terminal ig like domain DUF3566 PF12089.3 EMR73835.1 - 0.003 17.5 1.5 0.0057 16.6 1.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of unknown function (DUF3566) SHP PF03579.8 EMR73835.1 - 1.3 8.4 11.0 3 7.2 2.0 2.5 2 0 0 2 2 2 0 Small hydrophobic protein Claudin_2 PF13903.1 EMR73835.1 - 4.9 6.8 10.5 13 5.4 7.2 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Methyltransf_11 PF08241.7 EMR73842.1 - 5.6e-20 71.6 0.0 7.3e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73842.1 - 6.1e-18 64.8 0.0 7.7e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR73842.1 - 6.8e-15 55.1 0.0 8.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR73842.1 - 2.7e-13 50.1 0.0 3.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR73842.1 - 1.9e-12 47.5 0.0 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR73842.1 - 1.8e-08 33.7 0.0 2.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMR73842.1 - 5.3e-08 33.4 0.0 6.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EMR73842.1 - 8.2e-07 28.6 0.0 9.8e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EMR73842.1 - 2.4e-05 24.3 0.0 6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMR73842.1 - 3.4e-05 22.7 0.0 4.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 EMR73842.1 - 8.3e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EMR73842.1 - 0.0002 20.5 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EMR73842.1 - 0.00085 19.0 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.14 EMR73842.1 - 0.0012 18.8 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.7 EMR73842.1 - 0.0016 17.3 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_29 PF03141.11 EMR73842.1 - 0.0024 16.2 0.0 0.0031 15.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_11 PF13414.1 EMR73843.1 - 3.8e-13 48.8 2.5 2.8e-09 36.4 1.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMR73843.1 - 9.4e-12 43.9 5.5 0.0017 18.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMR73843.1 - 2.7e-10 39.4 3.3 0.0015 18.0 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMR73843.1 - 1.2e-09 38.6 0.1 4.4e-07 30.4 0.0 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMR73843.1 - 5.9e-08 32.3 0.2 0.012 15.7 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat PMT_2 PF13231.1 EMR73843.1 - 8.8e-08 32.2 13.3 8.8e-08 32.2 9.2 3.0 2 1 0 2 2 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_12 PF13424.1 EMR73843.1 - 1.8e-07 30.9 1.7 3e-07 30.2 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR73843.1 - 9.1e-06 25.9 0.1 0.04 14.2 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMR73843.1 - 0.00013 21.4 1.1 0.0078 15.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR73843.1 - 0.0002 21.6 0.7 2.2 8.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR73843.1 - 0.0017 18.8 0.3 1.4 9.7 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat Borrelia_orfX PF04160.7 EMR73843.1 - 3.8 7.2 10.9 0.11 12.3 1.5 2.2 2 0 0 2 2 2 0 Orf-X protein Gcd10p PF04189.8 EMR73844.1 - 0.049 12.7 0.3 0.065 12.3 0.2 1.2 1 0 0 1 1 1 0 Gcd10p family SHOCT PF09851.4 EMR73844.1 - 0.43 10.1 6.7 0.46 10.0 0.3 3.1 2 1 0 2 2 2 0 Short C-terminal domain zf-ribbon_3 PF13248.1 EMR73847.1 - 0.00073 18.6 1.9 0.0014 17.7 1.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EMR73847.1 - 0.0089 15.8 0.3 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EMR73847.1 - 0.014 14.8 3.8 0.036 13.5 2.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-B_box PF00643.19 EMR73847.1 - 0.048 13.5 0.6 0.068 13.0 0.4 1.2 1 0 0 1 1 1 0 B-box zinc finger zf-Mss51 PF13824.1 EMR73847.1 - 0.11 12.3 0.7 0.28 11.0 0.5 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 UPF0547 PF10571.4 EMR73847.1 - 1 9.1 3.8 2.5 7.8 2.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Glycos_transf_2 PF00535.21 EMR73861.1 - 3.5e-17 62.6 0.1 5.6e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR73861.1 - 1.6e-14 54.2 0.0 2.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMR73861.1 - 6.9e-07 29.1 0.0 9.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 NTP_transferase PF00483.18 EMR73861.1 - 0.05 12.8 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Glyco_transf_21 PF13506.1 EMR73861.1 - 0.05 12.8 0.1 0.13 11.5 0.0 1.7 2 1 0 2 2 2 0 Glycosyl transferase family 21 Radical_SAM PF04055.16 EMR73862.1 - 3.6e-11 43.5 0.5 6.3e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.1 EMR73862.1 - 2.9e-09 37.1 1.0 2.9e-09 37.1 0.7 3.0 4 0 0 4 4 4 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.1 EMR73862.1 - 8.1e-07 29.2 2.4 8.1e-07 29.2 1.7 2.3 2 1 1 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMR73862.1 - 8.7e-07 28.9 1.7 1.6e-06 28.1 0.6 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Phyto_Pns9_10 PF05878.6 EMR73862.1 - 0.01 14.8 1.0 0.015 14.3 0.7 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Sulfatase PF00884.18 EMR73863.1 - 1.6e-56 191.7 0.1 2e-56 191.4 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMR73863.1 - 4.7e-12 45.9 3.9 3.9e-11 42.9 2.7 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMR73863.1 - 2.4e-05 22.9 0.1 4e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EMR73863.1 - 0.00019 20.9 0.1 0.0014 18.0 0.0 2.4 3 0 0 3 3 3 1 Metalloenzyme superfamily PLRV_ORF5 PF01690.12 EMR73864.1 - 0.72 8.9 31.3 23 4.0 21.7 2.2 1 1 0 1 1 1 0 Potato leaf roll virus readthrough protein Trypan_PARP PF05887.6 EMR73864.1 - 0.72 9.6 18.3 1.3 8.8 12.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PMT_2 PF13231.1 EMR73865.1 - 3.9e-26 91.8 42.7 8.1e-26 90.8 14.0 3.6 3 0 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 EMR73865.1 - 2.6e-16 59.7 17.2 2.6e-16 59.7 11.9 3.0 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase NAD_binding_8 PF13450.1 EMR73866.1 - 4.9e-14 52.1 0.0 1.3e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GLF PF03275.8 EMR73866.1 - 2.3e-07 30.5 0.1 0.00024 20.6 0.0 2.4 2 0 0 2 2 2 2 UDP-galactopyranose mutase Amino_oxidase PF01593.19 EMR73866.1 - 1.1e-05 24.6 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EMR73866.1 - 4.1e-05 22.6 0.0 0.0013 17.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMR73866.1 - 0.0023 16.8 0.0 0.013 14.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR73866.1 - 0.0061 15.0 0.0 0.24 9.8 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EMR73866.1 - 0.0087 15.1 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR73866.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EMR73866.1 - 0.017 15.4 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR73866.1 - 0.06 13.3 0.0 0.24 11.4 0.0 2.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR73866.1 - 0.074 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR73866.1 - 0.088 11.7 0.0 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Epimerase PF01370.16 EMR73867.1 - 6.6e-53 179.5 0.0 8.6e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMR73867.1 - 1.8e-26 92.7 0.0 2.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMR73867.1 - 5e-26 91.2 2.4 2.2e-24 85.9 1.7 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMR73867.1 - 1.7e-25 89.2 0.2 2.1e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR73867.1 - 7.8e-15 54.4 0.1 2.7e-10 39.5 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EMR73867.1 - 4.9e-11 42.9 0.0 6.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR73867.1 - 5.8e-06 26.3 0.1 8.2e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase_Csub PF13950.1 EMR73867.1 - 0.004 17.0 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit DFP PF04127.10 EMR73867.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.10 EMR73867.1 - 0.024 14.5 0.0 0.071 12.9 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EMR73867.1 - 0.07 13.1 0.8 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NmrA PF05368.8 EMR73867.1 - 0.083 12.1 0.7 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family KR PF08659.5 EMR73867.1 - 0.1 12.2 0.1 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 EMR73867.1 - 0.16 10.9 0.2 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glycos_transf_1 PF00534.15 EMR73868.1 - 8.4e-24 83.8 0.1 1.9e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR73868.1 - 5.1e-11 42.8 0.0 7.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMR73868.1 - 2.5e-10 40.4 0.0 5.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 PAP2_C PF14360.1 EMR73868.1 - 0.035 14.3 0.4 0.035 14.3 0.3 2.2 1 1 1 2 2 2 0 PAP2 superfamily C-terminal UbiA PF01040.13 EMR73869.1 - 2.1e-19 69.7 13.1 2.1e-19 69.7 9.1 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_11 PF08241.7 EMR73870.1 - 4.7e-18 65.4 0.0 3e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73870.1 - 1.8e-16 60.0 0.1 2.6e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR73870.1 - 8.9e-13 47.8 0.0 1.4e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EMR73870.1 - 8.3e-12 45.1 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR73870.1 - 9.6e-12 45.1 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR73870.1 - 1.3e-11 44.8 0.0 7.6e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR73870.1 - 8.1e-09 36.0 0.0 1.4e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMR73870.1 - 2.4e-05 23.1 0.1 4.2e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EMR73870.1 - 4.1e-05 23.2 0.1 7.4e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMR73870.1 - 0.00037 19.6 0.0 0.00051 19.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EMR73870.1 - 0.0006 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR73870.1 - 0.00073 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EMR73870.1 - 0.0038 16.6 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 EMR73870.1 - 0.0074 15.4 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMR73870.1 - 0.0087 15.4 0.0 0.018 14.4 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase small domain MetW PF07021.7 EMR73870.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AviRa PF11599.3 EMR73870.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa RrnaAD PF00398.15 EMR73870.1 - 0.05 12.6 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.11 EMR73870.1 - 0.094 11.0 0.0 0.14 10.4 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 EMR73870.1 - 0.099 12.2 0.3 0.88 9.1 0.2 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase UPF0020 PF01170.13 EMR73870.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EMR73871.1 - 0.061 13.8 0.0 0.14 12.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR73872.1 - 4.6e-14 52.6 0.0 7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73872.1 - 1.9e-11 43.7 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR73872.1 - 4.1e-08 33.1 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR73872.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR73872.1 - 1.9e-06 27.2 0.0 3.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMR73872.1 - 1.8e-05 25.2 0.0 3.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR73872.1 - 2.7e-05 24.5 0.0 5.1e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain VCBS PF13517.1 EMR73873.1 - 0.055 13.8 0.9 0.055 13.8 0.6 1.7 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella NPCBM_assoc PF10633.4 EMR73874.1 - 0.00021 21.2 3.4 0.01 15.8 0.1 3.3 3 0 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.3 EMR73874.1 - 0.00051 20.1 0.1 0.08 13.0 0.0 3.0 2 1 1 3 3 3 2 IG-like fold at C-terminal of FixG, putative oxidoreductase HDV_ag PF01517.13 EMR73874.1 - 0.005 16.5 7.3 0.01 15.5 5.0 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen APG6 PF04111.7 EMR73874.1 - 0.015 14.3 10.8 0.023 13.7 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMR73874.1 - 0.046 11.5 7.1 0.067 11.0 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1034 PF06280.7 EMR73874.1 - 0.061 13.7 1.7 2 8.8 0.2 3.4 2 1 1 3 3 3 0 Fn3-like domain (DUF1034) AAA_32 PF13654.1 EMR73874.1 - 0.1 11.2 6.7 0.16 10.6 4.6 1.2 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 EMR73874.1 - 0.11 12.2 16.1 1.2 8.8 6.6 2.5 1 1 1 2 2 2 0 Prefoldin subunit DUF11 PF01345.13 EMR73874.1 - 0.22 11.5 6.9 3.5 7.7 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF11 DUF342 PF03961.8 EMR73874.1 - 0.31 9.4 5.7 0.56 8.5 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Vir_act_alpha_C PF10400.4 EMR73874.1 - 0.35 11.2 6.5 0.8 10.1 4.5 1.6 1 0 0 1 1 1 0 Virulence activator alpha C-term Nsp1_C PF05064.8 EMR73874.1 - 0.43 10.2 9.4 3.7 7.2 2.5 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region BLOC1_2 PF10046.4 EMR73874.1 - 0.69 10.0 6.6 0.94 9.6 3.3 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 EMR73874.1 - 2.4 8.0 13.9 3.9 7.3 9.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EMR73874.1 - 4.9 6.7 11.4 7.7 6.0 7.9 1.2 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EMR73874.1 - 5.9 7.3 7.3 5.7 7.4 1.5 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) FtsX PF02687.16 EMR73875.1 - 0.067 12.9 0.9 0.079 12.7 0.6 1.1 1 0 0 1 1 1 0 FtsX-like permease family Peptidase_S15 PF02129.13 EMR73876.1 - 5.5e-57 193.2 0.9 5.5e-57 193.2 0.7 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMR73876.1 - 3.2e-39 135.0 0.2 6.2e-39 134.1 0.2 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.16 EMR73876.1 - 0.00018 20.8 1.1 0.0019 17.4 0.4 2.5 1 1 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_11 PF08241.7 EMR73877.1 - 4.8e-10 39.8 0.0 6.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR73877.1 - 4.1e-07 29.7 0.0 4.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR73877.1 - 4.5e-06 25.9 0.0 5.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR73877.1 - 1.5e-05 25.3 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR73877.1 - 1.7e-05 25.3 0.0 2.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR73877.1 - 2.6e-05 24.0 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR73877.1 - 7e-05 22.8 0.0 8.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR73877.1 - 8.1e-05 22.0 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMR73877.1 - 0.00021 21.5 0.0 0.0003 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR73877.1 - 0.0013 18.3 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.12 EMR73877.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin PrmA PF06325.8 EMR73877.1 - 0.003 16.7 0.1 0.004 16.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EMR73877.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.0 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EMR73877.1 - 0.058 12.9 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Nol1_Nop2_Fmu PF01189.12 EMR73877.1 - 0.091 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 NOL1/NOP2/sun family Methyltransf_4 PF02390.12 EMR73877.1 - 0.097 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EMR73880.1 - 9e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 EMR73880.1 - 5.3e-11 42.3 0.0 6.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR73880.1 - 9.2e-11 42.0 0.0 1.4e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR73880.1 - 5.7e-10 39.7 0.0 8.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR73880.1 - 1.5e-09 37.7 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EMR73880.1 - 2.4e-06 27.1 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 EMR73880.1 - 3.5e-06 26.5 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMR73880.1 - 1.4e-05 25.3 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR73880.1 - 5.2e-05 23.6 0.0 9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR73880.1 - 0.0023 17.9 0.1 0.0039 17.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR73880.1 - 0.0026 16.9 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EMR73880.1 - 0.0034 16.4 0.0 0.0053 15.8 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase FmrO PF07091.6 EMR73880.1 - 0.0039 16.2 0.0 0.032 13.2 0.0 2.0 1 1 1 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) SAM_MT PF04445.8 EMR73880.1 - 0.031 13.4 0.6 0.66 9.0 0.4 2.1 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase N2227 PF07942.7 EMR73880.1 - 0.061 12.2 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein CMAS PF02353.15 EMR73880.1 - 0.066 12.2 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EMR73880.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.7 EMR73880.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW eIF-1a PF01176.14 EMR73882.1 - 1e-20 72.8 1.2 1.9e-20 72.0 0.6 1.7 2 1 0 2 2 2 1 Translation initiation factor 1A / IF-1 Beta-lactamase PF00144.19 EMR73883.1 - 2.4e-54 184.5 0.0 3.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EMR73883.1 - 2.4e-15 56.1 0.0 8.5e-07 28.7 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3471) DUF1435 PF07256.7 EMR73884.1 - 0.14 12.1 2.5 0.33 10.9 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1435) DUF3040 PF11239.3 EMR73884.1 - 1.6 8.7 7.1 2.8 8.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) HTH_34 PF13601.1 EMR73885.1 - 4.2e-26 90.7 0.0 5e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.2 EMR73885.1 - 6.6e-09 35.4 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 EMR73885.1 - 4.2e-06 26.3 0.0 7.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 EMR73885.1 - 3.7e-05 23.0 0.0 6.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PadR PF03551.9 EMR73885.1 - 5.2e-05 22.9 0.0 6.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.1 EMR73885.1 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_5 PF01022.15 EMR73885.1 - 0.0065 16.1 0.0 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 EMR73885.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF2513 PF10711.4 EMR73885.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.5 1 1 1 2 2 2 0 Hypothetical protein (DUF2513) MarR_2 PF12802.2 EMR73885.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.5 1 1 0 1 1 1 0 MarR family Laminin_G_3 PF13385.1 EMR73890.1 - 1.8e-10 41.2 0.0 2.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TFIIB PF00382.14 EMR73891.1 - 2.6e-38 129.6 4.6 1.7e-20 72.5 0.9 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMR73891.1 - 4.8e-17 60.9 1.1 9.4e-17 60.0 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EMR73891.1 - 7.1e-07 28.8 0.1 1.7e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.11 EMR73891.1 - 0.0017 17.6 1.1 0.15 11.3 0.1 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 zf-ribbon_3 PF13248.1 EMR73891.1 - 0.0018 17.4 0.9 0.0018 17.4 0.6 1.7 2 0 0 2 2 2 1 zinc-ribbon domain HTH_AsnC-type PF13404.1 EMR73891.1 - 0.015 14.8 0.1 0.067 12.7 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ribosomal_S27e PF01667.12 EMR73891.1 - 0.028 13.9 1.3 0.043 13.3 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 HTH_11 PF08279.7 EMR73891.1 - 0.051 13.2 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 HTH domain DZR PF12773.2 EMR73891.1 - 0.1 12.4 0.7 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 EMR73891.1 - 0.3 10.8 3.8 0.52 10.0 0.3 2.8 2 1 0 2 2 2 0 Nudix N-terminal Lar_restr_allev PF14354.1 EMR73891.1 - 0.35 11.1 2.9 0.87 9.9 0.1 2.6 3 0 0 3 3 3 0 Restriction alleviation protein Lar RNA_POL_M_15KD PF02150.11 EMR73891.1 - 0.49 10.1 5.7 3.9 7.2 1.1 2.6 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.7 EMR73891.1 - 0.81 9.5 4.0 18 5.2 0.3 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF3797 PF12677.2 EMR73891.1 - 1.1 8.9 3.2 2.3 7.9 1.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) A2L_zn_ribbon PF08792.5 EMR73891.1 - 1.6 8.3 3.9 0.82 9.2 0.6 2.0 2 1 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EMR73891.1 - 3.5 7.6 5.8 2.2 8.2 0.1 2.7 2 1 1 3 3 3 0 Zinc ribbon domain RRN7 PF11781.3 EMR73891.1 - 3.7 7.1 5.6 0.68 9.4 0.5 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Gar1 PF04410.9 EMR73892.1 - 3.7e-06 26.4 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SRP19 PF01922.12 EMR73893.1 - 7.7e-17 61.6 0.0 8.8e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 SRP19 protein Ribosomal_S8e PF01201.17 EMR73894.1 - 2.5e-33 115.0 2.2 2.7e-33 114.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF387 PF04079.11 EMR73895.1 - 1.1e-28 99.6 0.1 1.4e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) DUF1815 PF08844.5 EMR73895.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1815) HTH_20 PF12840.2 EMR73895.1 - 0.12 12.1 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain ScpA_ScpB PF02616.9 EMR73896.1 - 1.1e-07 31.7 0.6 1.1e-05 25.1 0.1 2.1 2 0 0 2 2 2 2 ScpA/B protein Cnd2 PF05786.9 EMR73896.1 - 0.062 11.8 0.1 0.78 8.1 0.0 1.9 2 0 0 2 2 2 0 Condensin complex subunit 2 Rad21_Rec8 PF04824.11 EMR73896.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein SMC_N PF02463.14 EMR73897.1 - 1.2e-63 214.3 0.0 2.1e-62 210.2 0.0 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMR73897.1 - 4.1e-21 75.1 0.0 1.3e-20 73.5 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMR73897.1 - 7.9e-14 52.2 4.3 1.4e-07 31.7 0.0 4.8 3 2 1 5 5 5 2 AAA domain AAA_23 PF13476.1 EMR73897.1 - 5.2e-11 43.2 86.8 1.2e-06 29.0 35.0 5.5 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMR73897.1 - 1.9e-08 33.7 0.0 3.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EMR73897.1 - 0.00012 21.3 31.4 0.00012 21.3 21.7 5.5 3 2 1 4 4 4 1 AAA ATPase domain DUF4200 PF13863.1 EMR73897.1 - 0.0052 16.7 16.8 0.0052 16.7 11.6 8.1 5 4 2 8 8 8 1 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EMR73897.1 - 0.022 13.9 32.9 0.46 9.6 4.0 5.7 2 2 4 6 6 6 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EMR73897.1 - 7.6 4.8 98.7 1.7 7.0 0.4 6.7 3 2 3 6 6 6 0 AAA domain Prenyltransf PF01255.14 EMR73898.1 - 3.1e-81 271.7 0.0 3.6e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF373 PF04123.8 EMR73899.1 - 2.6e-93 312.7 5.4 3.4e-93 312.4 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF3611 PF12263.3 EMR73899.1 - 0.87 8.9 10.4 2.2 7.6 1.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) TFIIB PF00382.14 EMR73900.1 - 6.6e-37 125.1 1.4 2.8e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMR73900.1 - 2.4e-15 55.5 1.0 4.1e-15 54.8 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EMR73900.1 - 1.3e-08 34.7 0.5 1.4e-05 25.0 0.1 2.4 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 EMR73900.1 - 0.00013 21.5 0.1 0.027 14.0 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_11 PF08279.7 EMR73900.1 - 0.0059 16.2 0.2 0.055 13.1 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_AsnC-type PF13404.1 EMR73900.1 - 0.0071 15.8 0.2 0.09 12.3 0.0 2.7 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 EMR73900.1 - 0.014 14.6 0.0 0.081 12.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 EMR73900.1 - 0.025 14.2 1.1 2.2 8.0 0.0 3.8 4 0 0 4 4 4 0 Homeodomain-like domain DZR PF12773.2 EMR73900.1 - 0.038 13.7 0.3 0.073 12.8 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EMR73900.1 - 0.071 12.3 0.4 0.11 11.6 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain HTH_38 PF13936.1 EMR73900.1 - 0.13 11.8 0.6 16 5.1 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Ribosomal_S27e PF01667.12 EMR73900.1 - 0.23 11.0 0.8 0.45 10.0 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.8 EMR73900.1 - 0.45 10.0 5.9 0.35 10.3 2.3 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Phage_integrase PF00589.17 EMR73901.1 - 2.1e-22 79.6 1.4 4.1e-22 78.6 1.0 1.4 1 0 0 1 1 1 1 Phage integrase family DUF885 PF05960.6 EMR73902.1 - 0.75 8.8 3.0 0.98 8.4 2.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) SBP_bac_5 PF00496.17 EMR73903.1 - 3.1e-60 203.9 1.1 1.5e-59 201.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF4398 PF14346.1 EMR73903.1 - 0.0016 18.4 2.9 0.0028 17.6 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) CoatB PF10389.4 EMR73903.1 - 0.43 10.4 4.8 3.9 7.4 0.5 2.6 2 0 0 2 2 2 0 Bacteriophage coat protein B SBP_bac_5 PF00496.17 EMR73905.1 - 4.4e-29 101.4 0.1 5.3e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3362 PF11842.3 EMR73914.1 - 0.0038 17.1 0.0 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3362) SNase PF00565.12 EMR73915.1 - 1.5e-10 41.3 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Peptidase_M73 PF12389.3 EMR73915.1 - 0.12 11.8 0.1 3.3 7.1 0.0 2.1 1 1 1 2 2 2 0 Camelysin metallo-endopeptidase NUC194 PF08163.7 EMR73916.1 - 0.1 11.4 0.2 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 NUC194 domain bZIP_2 PF07716.10 EMR73917.1 - 0.00055 19.6 1.8 0.0054 16.5 0.1 2.1 2 0 0 2 2 2 1 Basic region leucine zipper NTR2 PF15458.1 EMR73917.1 - 0.025 13.8 0.7 0.033 13.4 0.5 1.3 1 1 0 1 1 1 0 Nineteen complex-related protein 2 Filament PF00038.16 EMR73917.1 - 0.032 13.7 0.3 0.051 13.0 0.2 1.4 1 1 0 1 1 1 0 Intermediate filament protein DUF4200 PF13863.1 EMR73917.1 - 0.037 13.9 3.4 0.049 13.5 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Lipoprotein_20 PF13942.1 EMR73917.1 - 0.063 12.8 0.5 0.061 12.8 0.4 1.2 1 1 0 1 1 1 0 YfhG lipoprotein FAD_binding_8 PF08022.7 EMR73917.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD-binding domain bZIP_1 PF00170.16 EMR73917.1 - 0.18 11.8 3.8 0.18 11.7 0.3 2.0 2 0 0 2 2 2 0 bZIP transcription factor THOC7 PF05615.8 EMR73917.1 - 0.3 11.3 3.3 0.14 12.3 0.7 1.5 2 0 0 2 2 2 0 Tho complex subunit 7 zf-B_box PF00643.19 EMR73920.1 - 0.0052 16.6 5.6 0.0052 16.6 3.9 2.1 1 1 1 2 2 2 1 B-box zinc finger zf-HIT PF04438.11 EMR73920.1 - 0.031 13.9 6.6 0.16 11.6 3.5 2.3 2 1 0 2 2 2 0 HIT zinc finger zf-AN1 PF01428.11 EMR73920.1 - 0.053 13.3 7.2 0.087 12.7 5.0 1.5 1 1 0 1 1 1 0 AN1-like Zinc finger FYVE PF01363.16 EMR73920.1 - 0.06 13.2 11.6 0.16 11.9 8.1 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.1 EMR73920.1 - 0.26 11.1 9.6 0.46 10.3 6.6 1.6 1 1 0 1 1 1 0 Ring finger domain zf-MYND PF01753.13 EMR73920.1 - 0.4 10.6 7.2 8.4 6.3 5.0 2.3 1 1 0 1 1 1 0 MYND finger zf-C3HC4_2 PF13923.1 EMR73920.1 - 0.57 10.2 7.9 1.3 9.0 5.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EMR73920.1 - 0.7 9.8 13.3 7.3 6.5 9.2 2.5 1 1 0 1 1 1 0 IBR domain zf-C3HC4_3 PF13920.1 EMR73920.1 - 0.99 9.1 9.8 2.8 7.6 6.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 EMR73920.1 - 1.7 8.1 6.4 2.8 7.5 4.5 1.3 1 1 0 1 1 1 0 Transposase zinc-binding domain UPF1_Zn_bind PF09416.5 EMR73920.1 - 2.7 7.5 7.9 0.71 9.4 3.4 1.5 1 1 0 1 1 1 0 RNA helicase (UPF2 interacting domain) UPF0547 PF10571.4 EMR73920.1 - 3.1 7.5 8.6 52 3.6 0.1 3.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4 PF00097.20 EMR73920.1 - 3.8 7.2 9.7 0.99 9.1 3.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) A2L_zn_ribbon PF08792.5 EMR73920.1 - 4.1 6.9 13.7 3 7.4 0.4 3.0 2 1 0 2 2 2 0 A2L zinc ribbon domain DZR PF12773.2 EMR73920.1 - 6.2 6.7 12.2 1.8e+02 2.0 8.5 2.7 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L37e PF01907.14 EMR73920.1 - 7.2 6.5 9.8 1.2e+02 2.6 6.8 2.4 1 1 0 1 1 1 0 Ribosomal protein L37e PHD PF00628.24 EMR73920.1 - 8.5 6.1 12.5 35 4.1 8.7 1.9 1 1 0 1 1 1 0 PHD-finger Cas_Cas1 PF01867.11 EMR73921.1 - 2.9e-41 141.4 0.1 3.4e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 MtrG PF04210.8 EMR73922.1 - 0.12 12.0 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4507 PF14964.1 EMR73924.1 - 0.012 14.3 0.6 0.014 14.1 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) CDT1 PF08839.6 EMR73924.1 - 0.059 13.2 0.7 0.075 12.9 0.5 1.2 1 0 0 1 1 1 0 DNA replication factor CDT1 like Condensation PF00668.15 EMR73924.1 - 0.069 11.9 0.2 0.11 11.2 0.0 1.5 1 1 1 2 2 2 0 Condensation domain zf-C4H2 PF10146.4 EMR73924.1 - 0.97 9.4 7.6 1.1 9.2 5.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Glycos_transf_2 PF00535.21 EMR73925.1 - 3e-17 62.8 0.2 3.2e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR73925.1 - 1.1e-08 35.1 0.0 1.2e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transferase PF00483.18 EMR73925.1 - 0.0079 15.5 0.0 0.0091 15.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase DUF1131 PF06572.7 EMR73925.1 - 0.025 14.0 0.3 0.31 10.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1131) Glyco_tranf_2_4 PF13704.1 EMR73925.1 - 0.079 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF3024 PF11225.3 EMR73925.1 - 0.11 12.4 0.2 29 4.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3024) DUF362 PF04015.7 EMR73926.1 - 9e-46 155.9 0.1 1.2e-45 155.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF362) CARDB PF07705.6 EMR73927.1 - 2.2e-09 37.2 8.4 0.00019 21.4 0.2 4.3 4 0 0 4 4 4 3 CARDB DUF11 PF01345.13 EMR73927.1 - 8.2e-05 22.5 0.0 0.15 12.1 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function DUF11 Wzt_C PF14524.1 EMR73927.1 - 0.0053 16.4 1.8 0.018 14.7 0.1 2.6 3 0 0 3 3 3 1 Wzt C-terminal domain NPCBM_assoc PF10633.4 EMR73927.1 - 0.031 14.3 0.0 1.8 8.6 0.0 3.3 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase RibD_C PF01872.12 EMR73929.1 - 0.0023 17.5 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain RibD_C PF01872.12 EMR73930.1 - 2.4e-13 50.1 0.1 2.6e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Transglut_core PF01841.14 EMR73931.1 - 1.6e-24 86.2 0.0 2.9e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily CarboxypepD_reg PF13620.1 EMR73931.1 - 3e-12 46.4 10.1 5.8e-12 45.4 0.6 3.6 3 1 1 4 4 4 2 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMR73931.1 - 7.6e-07 29.0 3.7 6.4e-05 22.9 0.2 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4480) PEGA PF08308.6 EMR73931.1 - 1.5e-06 27.9 0.1 6.2e-06 25.9 0.1 2.2 1 0 0 1 1 1 1 PEGA domain Cna_B PF05738.8 EMR73931.1 - 0.00049 19.7 0.1 0.00049 19.7 0.1 3.6 4 0 0 4 4 4 1 Cna protein B-type domain Transglut_core3 PF13471.1 EMR73931.1 - 0.0037 17.0 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily CARDB PF07705.6 EMR73931.1 - 0.0064 16.5 5.5 0.021 14.8 1.2 3.2 3 0 0 3 3 3 1 CARDB DUF553 PF04473.7 EMR73931.1 - 0.012 14.8 0.6 0.2 10.8 0.3 2.8 2 1 0 2 2 2 0 Transglutaminase-like domain Glyoxalase_2 PF12681.2 EMR73932.1 - 1.2e-16 61.2 0.1 1.4e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EMR73932.1 - 0.00054 19.9 0.2 0.058 13.3 0.1 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMR73932.1 - 0.021 14.8 0.0 0.11 12.5 0.0 2.0 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_M20 PF01546.23 EMR73933.1 - 1.6e-06 27.7 0.1 6e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR73933.1 - 3e-06 26.9 0.0 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M24 PF00557.19 EMR73934.1 - 3.7e-31 108.3 0.0 5.2e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMR73934.1 - 7.9e-26 91.0 0.0 1.4e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain PRANC PF09372.5 EMR73934.1 - 0.051 13.5 0.6 0.14 12.1 0.4 1.7 1 0 0 1 1 1 0 PRANC domain PK_C PF02887.11 EMR73935.1 - 7e-12 44.9 0.6 1e-11 44.3 0.4 1.3 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain BRCT PF00533.21 EMR73935.1 - 0.0042 17.2 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Reticulon PF02453.12 EMR73936.1 - 0.013 15.1 7.7 0.042 13.4 0.7 2.3 1 1 1 2 2 2 0 Reticulon DUF3043 PF11241.3 EMR73936.1 - 1.4 8.4 3.5 0.64 9.5 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Spore_YabQ PF09578.5 EMR73936.1 - 3.3 7.7 14.1 3.5 7.6 6.1 2.6 1 1 2 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) DUF454 PF04304.8 EMR73936.1 - 6.9 6.7 12.2 1.9 8.5 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF454) DUF4212 PF13937.1 EMR73936.1 - 7.2 6.6 16.0 1.5 8.8 1.6 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4212) MFS_1 PF07690.11 EMR73937.1 - 3.4e-37 127.9 25.6 3.7e-19 68.6 5.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EMR73937.1 - 0.0034 15.5 1.8 0.0034 15.5 1.3 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.2 EMR73937.1 - 0.18 11.6 5.3 4.2 7.2 0.3 3.2 3 0 0 3 3 3 0 MFS_1 like family adh_short_C2 PF13561.1 EMR73938.1 - 5.2e-32 111.5 0.1 6e-32 111.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR73938.1 - 7.7e-32 110.5 0.1 1.4e-31 109.6 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR73938.1 - 5.6e-12 45.6 0.1 1e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR73938.1 - 8.6e-06 25.3 0.3 2.3e-05 23.9 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMR73938.1 - 0.00069 18.7 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 EMR73938.1 - 0.0052 15.5 0.3 0.0068 15.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.20 EMR73938.1 - 0.0052 16.0 0.1 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1815 PF08844.5 EMR73938.1 - 0.039 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) 2-Hacid_dh_C PF02826.14 EMR73938.1 - 0.07 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MacB_PCD PF12704.2 EMR73939.1 - 1e-38 133.2 1.6 1e-38 133.2 1.1 2.2 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.16 EMR73939.1 - 2.9e-22 78.6 11.5 2.9e-22 78.6 8.0 2.2 2 0 0 2 2 2 1 FtsX-like permease family DUF3087 PF11286.3 EMR73939.1 - 0.14 11.3 0.5 3 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) FUN14 PF04930.10 EMR73940.1 - 8.1e-11 42.0 4.4 9.2e-11 41.9 3.1 1.0 1 0 0 1 1 1 1 FUN14 family MtrD PF04207.7 EMR73940.1 - 0.037 13.4 2.4 0.037 13.4 1.6 1.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D TM2 PF05154.11 EMR73940.1 - 1.6 8.9 7.7 3.2 8.0 5.3 1.6 1 1 0 1 1 1 0 TM2 domain 2-Hacid_dh_C PF02826.14 EMR73962.1 - 1.9e-33 115.1 0.0 2.2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.21 EMR73963.1 - 2e-28 99.1 0.0 2.7e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EMR73963.1 - 2.4e-22 79.3 0.1 3.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EMR73963.1 - 7e-18 65.2 0.0 8.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMR73963.1 - 1.4e-08 34.7 0.1 1.8e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EMR73963.1 - 3.2e-07 29.8 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.1 EMR73963.1 - 0.0018 17.5 0.6 1.4 8.1 0.0 3.0 1 1 2 3 3 3 1 Glycosyltransferase like family Glyco_tranf_2_4 PF13704.1 EMR73963.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 SIMPL PF04402.9 EMR73980.1 - 6.9e-05 22.7 0.1 8.1e-05 22.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Phage_Coat_Gp8 PF05371.7 EMR73980.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage major coat protein, Gp8 MFS_1 PF07690.11 EMR74018.1 - 3.2e-58 197.1 42.5 8.7e-42 143.0 9.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR74018.1 - 3e-12 45.6 31.5 2.2e-10 39.5 5.5 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 EMR74018.1 - 1.9e-06 27.5 11.4 0.0057 16.4 0.0 3.8 3 0 0 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 EMR74018.1 - 3e-06 25.6 19.4 0.00015 20.0 2.1 2.1 1 1 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.19 EMR74018.1 - 0.00019 20.1 30.2 0.0026 16.4 3.5 3.7 2 2 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 EMR74018.1 - 0.0061 15.0 34.1 0.077 11.4 15.2 2.5 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like TRI12 PF06609.8 EMR74018.1 - 0.027 12.6 19.9 0.018 13.2 2.8 2.1 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EMR74018.1 - 0.028 13.0 17.1 0.08 11.4 0.5 3.2 3 1 0 3 3 3 0 LacY proton/sugar symporter OATP PF03137.15 EMR74018.1 - 0.043 11.8 17.0 0.05 11.6 2.6 3.9 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF4239 PF14023.1 EMR74018.1 - 0.16 11.3 2.0 17 4.7 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) RrnaAD PF00398.15 EMR74019.1 - 1e-29 103.3 0.0 1.5e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 EMR74019.1 - 2e-06 28.3 0.0 4.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR74019.1 - 9.2e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMR74019.1 - 0.0017 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EMR74019.1 - 0.002 17.7 0.0 0.0041 16.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMR74019.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EMR74019.1 - 0.014 15.8 0.0 0.034 14.6 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EMR74019.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase tRNA_U5-meth_tr PF05958.6 EMR74019.1 - 0.09 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PRMT5 PF05185.11 EMR74019.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DREV PF05219.7 EMR74019.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.14 EMR74019.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SDH_alpha PF03313.10 EMR74020.1 - 3.2e-32 111.6 8.4 3.6e-32 111.5 5.8 1.0 1 0 0 1 1 1 1 Serine dehydratase alpha chain Beta-lactamase PF00144.19 EMR74023.1 - 1.3e-51 175.5 0.0 2e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Chs3p PF12271.3 EMR74023.1 - 0.046 12.6 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase III catalytic subunit SH2 PF00017.19 EMR74023.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 SH2 domain Peptidase_M20 PF01546.23 EMR74024.1 - 1.5e-35 122.4 0.0 2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR74024.1 - 2.2e-18 66.0 0.0 3e-17 62.3 0.0 2.6 2 1 0 2 2 2 1 Peptidase dimerisation domain Aldo_ket_red PF00248.16 EMR74026.1 - 6.4e-42 143.3 0.0 1.2e-35 122.7 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Fer4_17 PF13534.1 EMR74026.1 - 7.1e-12 45.4 6.6 1.4e-11 44.5 4.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMR74026.1 - 1.3e-06 28.3 6.2 2.4e-06 27.4 4.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMR74026.1 - 1.3e-05 25.3 7.3 3.1e-05 24.1 5.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMR74026.1 - 7.9e-05 22.3 9.7 0.0023 17.6 7.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMR74026.1 - 0.00029 21.1 2.5 0.025 15.0 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EMR74026.1 - 0.0023 18.2 7.9 0.0055 17.0 5.5 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_20 PF14691.1 EMR74026.1 - 0.024 14.2 0.4 0.024 14.2 0.3 2.2 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4 PF00037.22 EMR74026.1 - 0.044 13.3 9.9 0.036 13.6 2.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 EMR74026.1 - 0.093 13.3 4.4 13 6.4 2.0 2.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_21 PF14697.1 EMR74026.1 - 0.26 11.1 5.8 1.2 9.0 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMR74026.1 - 0.33 10.9 12.7 0.3 11.0 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.1 EMR74026.1 - 2.8 8.7 10.1 21 5.9 7.5 2.1 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 EMR74026.1 - 4.7 7.8 16.4 1.3 9.5 2.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain POR_N PF01855.14 EMR74027.1 - 1.3e-06 28.1 0.2 1.5e-06 27.8 0.1 1.0 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg fn3 PF00041.16 EMR74038.1 - 1.7e-15 56.9 7.0 3.8e-07 30.1 0.2 3.4 3 0 0 3 3 3 2 Fibronectin type III domain DUF457 PF04307.9 EMR74040.1 - 9.5e-13 47.7 5.8 1.3e-12 47.3 4.0 1.1 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) Leu_zip PF15294.1 EMR74041.1 - 0.0038 16.3 2.4 0.0038 16.3 1.7 1.0 1 0 0 1 1 1 1 Leucine zipper NEMO PF11577.3 EMR74041.1 - 0.0097 15.6 1.8 0.012 15.3 1.2 1.2 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO CCDC92 PF14916.1 EMR74041.1 - 0.033 13.7 0.7 0.044 13.3 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Cep57_CLD_2 PF14197.1 EMR74041.1 - 0.034 14.1 1.3 0.043 13.7 0.9 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF536 PF04394.9 EMR74041.1 - 0.06 13.0 5.3 0.083 12.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF536 DctA-YdbH PF11739.3 EMR74041.1 - 0.062 12.7 0.2 0.075 12.4 0.1 1.0 1 0 0 1 1 1 0 Dicarboxylate transport Peptidase_M3 PF01432.15 EMR74041.1 - 0.064 12.2 0.6 0.074 12.0 0.4 1.0 1 0 0 1 1 1 0 Peptidase family M3 Med10 PF09748.4 EMR74041.1 - 0.068 12.9 0.4 0.072 12.9 0.2 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex TnpV PF14198.1 EMR74041.1 - 0.082 12.8 2.1 0.09 12.6 1.4 1.0 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Syntaxin PF00804.20 EMR74041.1 - 0.098 12.8 1.0 0.11 12.6 0.7 1.1 1 0 0 1 1 1 0 Syntaxin DUF2570 PF10828.3 EMR74041.1 - 0.15 11.6 1.4 0.16 11.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SlyX PF04102.7 EMR74041.1 - 0.18 12.1 0.6 0.2 12.0 0.4 1.2 1 0 0 1 1 1 0 SlyX Spc24 PF08286.6 EMR74041.1 - 0.26 11.0 2.5 0.3 10.7 1.7 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EMR74041.1 - 1 8.9 3.9 1.8 8.0 2.7 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF2387 PF09526.5 EMR74043.1 - 0.0038 17.1 0.2 0.0048 16.7 0.2 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) TF_Zn_Ribbon PF08271.7 EMR74043.1 - 0.0046 16.2 3.7 0.008 15.4 2.6 1.5 1 1 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.1 EMR74043.1 - 0.0065 16.7 1.9 0.008 16.4 1.4 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar DUF3797 PF12677.2 EMR74043.1 - 0.0087 15.6 0.7 1.7 8.3 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3797) RNA_POL_M_15KD PF02150.11 EMR74043.1 - 0.02 14.5 1.0 0.03 13.9 0.7 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EMR74043.1 - 0.022 14.5 0.5 0.028 14.2 0.4 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMR74043.1 - 0.033 14.1 1.1 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EMR74043.1 - 0.036 13.7 0.5 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 EMR74043.1 - 0.052 13.2 0.3 0.059 13.0 0.2 1.0 1 0 0 1 1 1 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.1 EMR74043.1 - 0.24 10.6 4.2 0.46 9.7 2.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 EMR74043.1 - 0.74 9.5 6.6 5.9 6.6 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-CSL PF05207.8 EMR74043.1 - 1.5 8.4 4.3 0.31 10.5 0.2 1.8 1 1 1 2 2 2 0 CSL zinc finger zf-H2C2_2 PF13465.1 EMR74043.1 - 4.6 7.7 5.8 4.7 7.6 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain XPA_N PF01286.13 EMR74043.1 - 4.7 6.9 6.8 14 5.4 1.3 2.4 2 1 0 2 2 2 0 XPA protein N-terminal Fer4_21 PF14697.1 EMR74044.1 - 6.8e-06 25.8 3.4 7.9e-06 25.6 2.3 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EMR74044.1 - 0.00082 19.7 3.3 0.0012 19.2 2.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMR74044.1 - 0.0072 17.0 5.1 0.22 12.3 2.6 2.1 1 1 1 2 2 2 1 4Fe-4S double cluster binding domain Fer4_11 PF13247.1 EMR74044.1 - 0.049 13.5 1.5 0.054 13.3 1.1 1.1 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMR74044.1 - 0.16 12.2 4.1 0.22 11.7 2.8 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.22 EMR74044.1 - 0.24 11.0 5.3 0.75 9.4 1.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EMR74044.1 - 4.5 7.3 6.2 14 5.7 1.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain HxlR PF01638.12 EMR74045.1 - 7.2e-19 67.2 0.2 1.7e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 HxlR-like helix-turn-helix PadR PF03551.9 EMR74045.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.2 EMR74045.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_34 PF13601.1 EMR74045.1 - 0.033 14.2 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.1 EMR74045.1 - 0.042 13.2 0.7 0.079 12.3 0.5 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_31 PF13847.1 EMR74046.1 - 1.2e-15 57.4 0.0 1.7e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR74046.1 - 1.5e-13 50.7 0.1 3.5e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR74046.1 - 3.9e-12 45.7 0.0 5.2e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR74046.1 - 5.6e-12 46.0 0.0 8.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR74046.1 - 7.7e-12 45.5 0.0 1.5e-11 44.6 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR74046.1 - 9.3e-11 41.7 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR74046.1 - 2.4e-10 40.9 0.0 3.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR74046.1 - 3.7e-09 36.8 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR74046.1 - 2.8e-08 33.3 0.0 4.4e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMR74046.1 - 4.3e-08 32.9 0.0 5.3e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EMR74046.1 - 1.7e-06 27.4 0.0 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EMR74046.1 - 2.2e-05 23.5 0.0 0.0001 21.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.6 EMR74046.1 - 0.00075 18.9 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EMR74046.1 - 0.0037 16.3 0.0 0.0047 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EMR74046.1 - 0.004 17.1 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_3 PF01596.12 EMR74046.1 - 0.0046 16.0 0.0 0.006 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMR74046.1 - 0.012 16.4 0.0 0.02 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EMR74046.1 - 0.043 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GCD14 PF08704.5 EMR74046.1 - 0.065 12.7 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.15 EMR74046.1 - 0.076 12.0 0.0 0.094 11.7 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EMR74046.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 EMR74046.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Lactamase_B_2 PF12706.2 EMR74047.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMR74047.1 - 4.4e-05 23.2 4.6 0.00037 20.2 3.2 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF362 PF04015.7 EMR74048.1 - 1.5e-40 138.8 0.4 1.9e-40 138.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF362) DUF2088 PF09861.4 EMR74048.1 - 0.065 12.2 0.1 0.091 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) Ldh_2 PF02615.9 EMR74049.1 - 1.3e-74 250.8 0.1 1.8e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase TPP_enzyme_N PF02776.13 EMR74050.1 - 1.7e-40 138.2 0.0 2.8e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR74050.1 - 8.6e-31 106.5 0.0 1.8e-30 105.4 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMR74050.1 - 0.0001 21.8 0.1 0.00024 20.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Bin3 PF06859.7 EMR74050.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Aldolase_2 PF10120.4 EMR74051.1 - 1.3e-38 132.0 0.0 1.8e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Putative aldolase Methyltransf_11 PF08241.7 EMR74052.1 - 2e-09 37.7 0.0 5.4e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR74052.1 - 0.00024 20.8 0.0 0.00043 20.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR74052.1 - 0.019 15.3 0.0 0.077 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMR74052.1 - 0.041 14.4 0.0 0.057 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Thia_YuaJ PF09515.5 EMR74053.1 - 1.3e-15 57.6 1.0 1.4e-15 57.4 0.7 1.0 1 0 0 1 1 1 1 Thiamine transporter protein (Thia_YuaJ) DUF3816 PF12822.2 EMR74053.1 - 3.8e-05 23.6 1.1 4.1e-05 23.5 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) ECF-ribofla_trS PF07155.7 EMR74053.1 - 0.00017 21.3 0.4 0.00018 21.2 0.2 1.0 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component DUF4118 PF13493.1 EMR74053.1 - 0.00039 20.5 0.2 0.00043 20.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) DUF3165 PF11364.3 EMR74053.1 - 0.01 15.9 0.2 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) MFS_1 PF07690.11 EMR74127.1 - 2.3e-41 141.6 29.2 7.4e-32 110.4 6.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR74127.1 - 1e-09 37.5 15.2 2.3e-09 36.3 2.7 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EMR74127.1 - 7.1e-09 34.5 15.0 4.4e-06 25.3 5.1 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EMR74127.1 - 5.6e-06 24.7 1.6 7.6e-06 24.3 1.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector LacY_symp PF01306.14 EMR74127.1 - 5.4e-05 21.9 11.2 0.022 13.3 0.6 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1_like PF12832.2 EMR74127.1 - 0.019 14.7 8.2 0.48 10.2 0.1 3.2 3 1 1 4 4 4 0 MFS_1 like family NdhL PF10716.4 EMR74127.1 - 0.14 11.9 7.7 0.46 10.2 0.7 2.7 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit OATP PF03137.15 EMR74127.1 - 4 5.3 6.6 1.2 7.1 0.5 2.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_5 PF12695.2 EMR74128.1 - 1.1e-27 96.5 0.0 1.6e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR74128.1 - 1.9e-10 41.0 0.0 4.9e-08 33.1 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMR74128.1 - 7.4e-05 21.7 0.1 0.00044 19.2 0.1 1.9 1 1 1 2 2 2 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EMR74128.1 - 0.00031 20.3 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EMR74128.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.16 EMR74128.1 - 0.0099 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EMR74128.1 - 0.012 14.8 0.0 1.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 EMR74128.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EMR74128.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EMR74128.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EMR74128.1 - 0.072 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.8 EMR74128.1 - 0.074 11.3 0.0 3.2 5.9 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2974 PF11187.3 EMR74128.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SHOCT PF09851.4 EMR74130.1 - 3.8e-05 22.9 0.0 6.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.7 EMR74130.1 - 0.061 13.1 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle protein G MFS_1 PF07690.11 EMR74131.1 - 3.2e-57 193.8 38.1 1.8e-32 112.4 11.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EMR74131.1 - 4.8e-11 41.4 8.7 1.6e-06 26.5 0.2 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 EMR74131.1 - 5.2e-09 34.9 21.0 1.3e-05 23.8 4.3 2.6 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 EMR74131.1 - 1.7e-08 33.4 25.4 4.8e-05 22.1 4.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Nuc_H_symport PF03825.11 EMR74131.1 - 0.00012 20.9 3.2 0.00012 20.9 2.2 2.1 1 1 1 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.14 EMR74131.1 - 0.00034 19.2 22.3 0.0074 14.8 4.6 2.6 2 1 0 2 2 2 2 LacY proton/sugar symporter FtsX PF02687.16 EMR74133.1 - 0.067 12.9 0.9 0.079 12.7 0.6 1.1 1 0 0 1 1 1 0 FtsX-like permease family UbiA PF01040.13 EMR74134.1 - 5.1e-32 111.1 19.3 6.4e-32 110.7 13.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Response_reg PF00072.19 EMR74135.1 - 2.5e-18 66.1 0.1 5.5e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EMR74135.1 - 8.9e-11 42.0 0.0 2.3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c PF02518.21 EMR74135.1 - 5.4e-10 38.9 0.1 1.4e-09 37.6 0.0 1.8 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.5 EMR74135.1 - 1.7e-08 34.4 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EMR74135.1 - 2e-08 34.0 0.0 5.2e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EMR74135.1 - 2.6e-05 23.8 0.0 6.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 EMR74135.1 - 3.7e-05 23.7 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.1 EMR74135.1 - 0.00042 19.9 0.1 0.0039 16.8 0.0 2.5 2 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOB_a PF14689.1 EMR74135.1 - 0.001 18.6 0.1 0.0045 16.5 0.0 2.1 2 0 0 2 2 2 1 Sensor_kinase_SpoOB-type, alpha-helical domain HisKA PF00512.20 EMR74135.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HisKA_2 PF07568.7 EMR74135.1 - 0.038 13.8 0.0 0.48 10.3 0.0 2.7 2 0 0 2 2 2 0 Histidine kinase Fe-ADH PF00465.14 EMR74136.1 - 1e-112 376.4 0.0 1.2e-112 376.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMR74136.1 - 8.4e-22 77.6 0.1 8.2e-12 44.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF169 PF02596.10 EMR74137.1 - 0.00062 19.2 0.1 0.00064 19.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ArCR, COG2043 Myosin_tail_1 PF01576.14 EMR74139.1 - 2.9e-05 22.0 11.6 3.6e-05 21.7 8.1 1.1 1 0 0 1 1 1 1 Myosin tail Mgr1 PF08602.5 EMR74139.1 - 0.00079 18.5 1.7 0.0011 18.1 1.2 1.2 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit AAA_13 PF13166.1 EMR74139.1 - 0.00079 18.0 2.1 0.00098 17.7 1.5 1.1 1 0 0 1 1 1 1 AAA domain ATG16 PF08614.6 EMR74139.1 - 0.00088 19.1 3.2 0.00099 18.9 2.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PspA_IM30 PF04012.7 EMR74139.1 - 0.0022 17.3 8.0 0.024 13.9 2.4 2.2 1 1 1 2 2 2 1 PspA/IM30 family CCDC155 PF14662.1 EMR74139.1 - 0.0037 16.8 4.7 0.0052 16.4 3.2 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Seryl_tRNA_N PF02403.17 EMR74139.1 - 0.004 17.1 10.7 0.01 15.8 5.7 2.2 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 EMR74139.1 - 0.0062 15.7 0.4 0.0076 15.4 0.2 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein IncA PF04156.9 EMR74139.1 - 0.0085 15.7 7.0 0.011 15.2 4.8 1.3 1 0 0 1 1 1 1 IncA protein Helicase_IV_N PF12462.3 EMR74139.1 - 0.0093 15.6 1.9 0.011 15.3 1.0 1.4 1 1 0 1 1 1 1 DNA helicase IV / RNA helicase N terminal CENP-F_leu_zip PF10473.4 EMR74139.1 - 0.01 15.7 7.9 0.01 15.7 5.5 1.7 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.1 EMR74139.1 - 0.014 15.0 6.1 0.022 14.4 4.2 1.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Prp19 PF08606.6 EMR74139.1 - 0.033 13.9 0.5 0.069 12.8 0.3 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like bZIP_1 PF00170.16 EMR74139.1 - 0.033 14.1 1.1 0.033 14.1 0.8 2.1 2 0 0 2 2 1 0 bZIP transcription factor Atg14 PF10186.4 EMR74139.1 - 0.037 12.9 8.2 0.047 12.6 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAUS6_N PF14661.1 EMR74139.1 - 0.039 13.3 4.9 0.057 12.7 3.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 EMR74139.1 - 0.043 13.5 1.5 0.053 13.2 1.1 1.1 1 0 0 1 1 1 0 HD domain Vps5 PF09325.5 EMR74139.1 - 0.064 12.4 7.6 0.074 12.2 2.8 2.0 2 0 0 2 2 2 0 Vps5 C terminal like FliJ PF02050.11 EMR74139.1 - 0.064 13.2 6.9 0.043 13.8 3.1 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein BLOC1_2 PF10046.4 EMR74139.1 - 0.066 13.3 4.5 0.11 12.6 2.3 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3508 PF12018.3 EMR74139.1 - 0.075 12.0 4.4 0.11 11.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) EURL PF06937.6 EMR74139.1 - 0.075 12.4 3.4 0.081 12.3 2.4 1.1 1 0 0 1 1 1 0 EURL protein DUF948 PF06103.6 EMR74139.1 - 0.083 12.7 0.9 0.93 9.4 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pox_A_type_inc PF04508.7 EMR74139.1 - 0.084 12.6 8.9 0.51 10.2 0.2 3.7 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4201 PF13870.1 EMR74139.1 - 0.086 12.2 8.5 0.16 11.3 5.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 EMR74139.1 - 0.13 12.5 3.4 0.22 11.8 1.0 2.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Rootletin PF15035.1 EMR74139.1 - 0.13 12.2 9.3 0.3 11.0 6.2 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 EMR74139.1 - 0.14 10.0 4.0 0.17 9.7 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EMR74139.1 - 0.15 11.8 0.7 0.45 10.3 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF964 PF06133.6 EMR74139.1 - 0.16 11.9 8.1 0.32 11.0 5.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF964) SSFA2_C PF14723.1 EMR74139.1 - 0.19 11.4 2.4 0.26 11.0 1.7 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus MbeD_MobD PF04899.7 EMR74139.1 - 0.19 11.6 3.4 0.91 9.4 2.3 2.2 1 1 0 1 1 1 0 MbeD/MobD like DUF4407 PF14362.1 EMR74139.1 - 0.2 10.5 3.8 0.3 10.0 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 EMR74139.1 - 0.24 10.8 3.8 1.3 8.5 2.7 2.2 1 1 0 1 1 1 0 Septum formation initiator DUF1664 PF07889.7 EMR74139.1 - 0.26 11.0 6.0 0.16 11.7 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EMR74139.1 - 0.28 10.1 7.9 0.37 9.8 5.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 EMR74139.1 - 0.3 10.9 3.8 0.25 11.2 0.6 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.9 EMR74139.1 - 0.35 10.7 10.5 0.5 10.2 7.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lipoprotein_20 PF13942.1 EMR74139.1 - 0.36 10.3 8.1 0.29 10.6 3.3 2.1 1 1 1 2 2 2 0 YfhG lipoprotein Prefoldin PF02996.12 EMR74139.1 - 0.42 10.2 6.0 1.2 8.7 1.1 2.4 1 1 1 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 EMR74139.1 - 0.42 11.0 7.8 2.8 8.3 4.0 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 EMR74139.1 - 0.54 10.0 10.2 1.3 8.8 7.1 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF4140 PF13600.1 EMR74139.1 - 0.65 10.4 5.1 2 8.8 3.5 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.8 EMR74139.1 - 0.72 8.8 3.7 2.1 7.3 3.1 1.4 2 0 0 2 2 1 0 TMPIT-like protein Ax_dynein_light PF10211.4 EMR74139.1 - 0.84 9.4 9.7 0.87 9.4 1.5 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF724 PF05266.9 EMR74139.1 - 1.2 8.6 8.8 2 8.0 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.8 EMR74139.1 - 1.5 9.6 5.9 13 6.6 2.9 2.4 1 1 1 2 2 2 0 Occludin homology domain Spc24 PF08286.6 EMR74139.1 - 1.8 8.3 6.2 2.6 7.7 3.1 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.1 EMR74139.1 - 2.3 8.6 9.2 0.3 11.4 1.2 2.8 2 1 2 4 4 2 0 Snapin/Pallidin SlyX PF04102.7 EMR74139.1 - 3.2 8.1 6.3 7.1 7.0 1.9 2.8 2 1 1 3 3 2 0 SlyX Kinetocho_Slk19 PF12709.2 EMR74139.1 - 4.2 7.5 11.8 0.57 10.2 0.5 3.1 2 1 1 3 3 3 0 Central kinetochore-associated TMF_DNA_bd PF12329.3 EMR74139.1 - 5.4 6.8 15.0 0.049 13.4 4.2 2.2 3 1 0 3 3 1 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 EMR74139.1 - 6.6 6.7 7.6 0.29 11.0 0.4 2.4 4 0 0 4 4 1 0 Flagella accessory protein C (FlaC) Phage_GPO PF05929.6 EMR74139.1 - 9.5 5.3 8.3 5.5 6.1 2.9 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MscL PF01741.13 EMR74140.1 - 3.6e-19 69.1 6.2 3.6e-19 69.1 4.3 1.4 2 0 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL Fumarate_red_D PF02313.12 EMR74140.1 - 0.013 15.3 4.7 0.023 14.5 3.2 1.4 1 0 0 1 1 1 0 Fumarate reductase subunit D DUF1508 PF07411.7 EMR74141.1 - 9.5e-44 146.6 1.5 9.4e-23 79.3 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1508) Oxidored-like PF09791.4 EMR74141.1 - 0.009 15.4 0.1 0.17 11.3 0.1 2.2 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal FecR PF04773.8 EMR74141.1 - 0.064 13.4 0.0 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 FecR protein Metallophos PF00149.23 EMR74142.1 - 1.9e-19 69.8 1.7 5.6e-19 68.3 1.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EMR74142.1 - 4e-15 56.1 0.0 7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain CarboxypepD_reg PF13620.1 EMR74143.1 - 1.8e-05 24.7 0.0 4.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Trypan_PARP PF05887.6 EMR74143.1 - 0.017 14.9 7.6 0.017 14.9 5.2 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PEMT PF04191.8 EMR74144.1 - 2.8e-08 33.8 0.1 3.5e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 EMR74144.1 - 0.0038 17.3 0.1 0.0047 17.1 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CRPA PF05745.6 EMR74144.1 - 0.0045 16.7 0.1 0.0065 16.2 0.1 1.2 1 0 0 1 1 1 1 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Kelch_4 PF13418.1 EMR74145.1 - 0.047 13.4 3.3 12 5.7 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain HTH_45 PF14947.1 EMR74152.1 - 3e-25 87.8 1.2 3.3e-25 87.6 0.9 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix TetR_C_8 PF14278.1 EMR74152.1 - 0.0021 18.3 1.0 0.0026 18.0 0.7 1.1 1 0 0 1 1 1 1 Transcriptional regulator C-terminal region DUF4364 PF14277.1 EMR74152.1 - 0.012 15.1 0.2 0.013 15.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) HemN_C PF06969.11 EMR74152.1 - 0.042 13.9 0.0 0.063 13.3 0.0 1.3 1 1 0 1 1 1 0 HemN C-terminal domain MotA_activ PF09114.5 EMR74152.1 - 0.053 13.2 0.1 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor MotA, activation domain Methyltransf_25 PF13649.1 EMR74153.1 - 2.4e-12 47.1 0.1 5.3e-12 45.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR74153.1 - 6e-11 42.9 0.0 1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR74153.1 - 1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR74153.1 - 1.5e-09 38.2 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR74153.1 - 3.1e-08 33.5 0.0 1.1e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR74153.1 - 8.6e-08 31.5 0.0 3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR74153.1 - 3e-06 27.6 0.0 4.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR74153.1 - 9.5e-05 22.4 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EMR74153.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.6 EMR74153.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EMR74153.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DNAPolymera_Pol PF11590.3 EMR74153.1 - 0.026 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol MTS PF05175.9 EMR74153.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DGC PF08859.6 EMR74157.1 - 2.8e-15 56.1 0.1 3.3e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 DGC domain OsmC PF02566.14 EMR74158.1 - 6e-13 48.8 0.0 7.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein Rubrerythrin PF02915.12 EMR74159.1 - 8e-05 22.9 0.2 0.0036 17.6 0.7 2.0 1 1 1 2 2 2 2 Rubrerythrin Aldedh PF00171.17 EMR74160.1 - 1.5e-137 458.7 0.0 1.7e-137 458.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR74160.1 - 0.03 13.0 0.0 0.045 12.4 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) SDH_sah PF01972.11 EMR74164.1 - 2.6e-98 328.3 0.2 3.1e-98 328.0 0.2 1.0 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.18 EMR74164.1 - 1.7e-06 27.8 0.2 2.6e-06 27.2 0.2 1.5 1 1 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.13 EMR74164.1 - 0.0032 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 ECH PF00378.15 EMR74164.1 - 0.0057 15.8 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PHP_C PF13263.1 EMR74168.1 - 7.7e-17 60.5 0.0 1.4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 PHP-associated PHP PF02811.14 EMR74168.1 - 2.9e-13 49.9 0.0 3.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 PHP domain Rep_3 PF01051.16 EMR74169.1 - 0.019 14.5 1.8 0.024 14.2 1.2 1.2 1 0 0 1 1 1 0 Initiator Replication protein Fzo_mitofusin PF04799.8 EMR74169.1 - 0.036 13.4 1.0 0.066 12.6 0.7 1.4 1 0 0 1 1 1 0 fzo-like conserved region Peptidase_M24 PF00557.19 EMR74174.1 - 7.6e-31 107.3 0.1 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMR74174.1 - 8.3e-19 68.3 0.0 1.3e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain GFO_IDH_MocA PF01408.17 EMR74176.1 - 1.8e-22 80.1 0.0 2.5e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR74176.1 - 1.9e-13 50.2 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF362 PF04015.7 EMR74189.1 - 2.8e-14 53.0 0.2 5.1e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF362) DUF3590 PF12148.3 EMR74189.1 - 0.022 14.3 0.5 51 3.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3590) Acetyltransf_9 PF13527.1 EMR74190.1 - 6.2e-09 35.7 0.0 6.2e-07 29.3 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR74190.1 - 0.00083 19.3 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR74190.1 - 0.031 14.3 0.0 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Polysacc_synt PF01943.12 EMR74191.1 - 1.6e-28 99.7 36.8 1.6e-28 99.7 25.5 3.1 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.1 EMR74191.1 - 1.2e-11 44.5 27.0 7.9e-11 41.8 16.6 3.3 2 2 2 4 4 4 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.1 EMR74191.1 - 2.1e-07 30.8 58.3 5e-06 26.3 16.2 4.2 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 EMR74191.1 - 0.0049 16.4 8.1 0.0049 16.4 5.6 5.0 2 2 3 5 5 5 1 MatE DUF1616 PF07760.6 EMR74193.1 - 1.9e-17 63.3 18.0 3.4e-17 62.5 12.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) AsmA_1 PF13109.1 EMR74193.1 - 0.037 13.2 1.4 0.053 12.7 1.0 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region Polysacc_deac_1 PF01522.16 EMR74195.1 - 6.8e-19 67.7 0.0 1.3e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glycos_transf_2 PF00535.21 EMR74197.1 - 6.1e-29 100.8 0.2 9.5e-29 100.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR74197.1 - 6.4e-24 85.0 0.0 1.1e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMR74197.1 - 6.1e-13 48.4 0.0 4.8e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EMR74197.1 - 1e-12 47.7 0.9 1.4e-12 47.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMR74197.1 - 3.5e-10 39.9 0.7 3.5e-10 39.9 0.5 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 EMR74197.1 - 4.2e-05 23.7 0.0 7.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 GNT-I PF03071.10 EMR74197.1 - 0.0058 15.2 0.0 0.0088 14.6 0.0 1.2 1 0 0 1 1 1 1 GNT-I family Radical_SAM PF04055.16 EMR74198.1 - 8.4e-18 65.0 0.1 1.2e-17 64.5 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EMR74198.1 - 8.3e-09 35.6 0.2 1.6e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMR74198.1 - 5e-08 33.0 0.1 9.1e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain AMP-binding PF00501.23 EMR74199.1 - 0.00025 19.5 0.0 0.00065 18.2 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 EMR74200.1 - 1.8e-06 26.6 0.0 2.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FemAB PF02388.11 EMR74201.1 - 9.4e-19 67.3 2.8 7.4e-12 44.6 0.1 2.7 2 1 1 3 3 3 2 FemAB family Acetyltransf_6 PF13480.1 EMR74201.1 - 2.5e-13 50.1 0.0 4.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF482 PF04339.7 EMR74201.1 - 0.0054 15.6 0.0 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF482 Glycos_transf_1 PF00534.15 EMR74202.1 - 1.3e-37 128.9 0.0 1.6e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR74202.1 - 1.6e-16 60.6 0.0 2e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMR74202.1 - 4.5e-10 39.6 0.0 6.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EMR74202.1 - 0.025 13.0 0.1 0.19 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EMR74203.1 - 0.0015 18.0 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EMR74203.1 - 0.063 13.4 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EMR74204.1 - 1.6e-42 144.8 0.0 2.5e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR74204.1 - 4e-20 72.3 0.0 7.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMR74204.1 - 6.2e-12 45.6 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMR74204.1 - 2.2e-10 40.5 0.0 3.7e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF1616 PF07760.6 EMR74205.1 - 0.0084 15.2 2.3 0.0099 15.0 1.5 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1616) Epimerase PF01370.16 EMR74207.1 - 1.3e-45 155.6 0.0 1.6e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR74207.1 - 1.1e-09 37.4 0.0 2.7e-07 29.5 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMR74207.1 - 3e-08 32.8 0.0 4.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMR74207.1 - 3.2e-07 29.5 0.2 0.0019 17.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EMR74207.1 - 3.6e-07 29.3 0.2 0.0096 14.8 0.1 2.7 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMR74207.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Glycos_transf_2 PF00535.21 EMR74208.1 - 3.2e-32 111.5 0.3 4.5e-32 111.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR74208.1 - 6.4e-14 52.2 0.0 8.2e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMR74208.1 - 5.8e-09 35.4 1.0 4.6e-08 32.4 0.2 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EMR74208.1 - 0.00012 22.2 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 GNT-I PF03071.10 EMR74208.1 - 0.025 13.1 0.7 0.036 12.6 0.1 1.6 2 0 0 2 2 2 0 GNT-I family NTP_transferase PF00483.18 EMR74209.1 - 3.7e-31 108.3 0.0 4.2e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EMR74209.1 - 3.3e-11 43.5 0.0 5.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EMR74209.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Antitoxin-MazE PF04014.13 EMR74210.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Antidote-toxin recognition MazE HrpA_pilin PF09589.5 EMR74211.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 HrpA pilus formation protein UDPG_MGDP_dh_N PF03721.9 EMR74212.1 - 4.9e-56 189.0 0.0 7.9e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EMR74212.1 - 3e-34 117.1 0.0 5.1e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EMR74212.1 - 3.9e-26 91.2 0.0 9.2e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.12 EMR74212.1 - 0.00031 21.0 0.0 0.34 11.3 0.0 2.8 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EMR74212.1 - 0.0078 16.2 0.0 0.85 9.6 0.0 3.1 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EMR74212.1 - 0.0079 16.0 0.0 0.98 9.2 0.1 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EMR74212.1 - 0.068 12.8 0.1 0.26 10.9 0.0 2.0 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EMR74212.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EMR74213.1 - 2.9e-62 210.2 0.1 4e-62 209.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR74213.1 - 1.6e-25 89.4 0.1 2.1e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR74213.1 - 3.4e-20 72.1 0.0 2e-19 69.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMR74213.1 - 1.9e-16 59.8 0.0 2.6e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMR74213.1 - 2.6e-12 46.1 0.6 4.4e-11 42.1 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMR74213.1 - 1.7e-11 44.4 0.0 4.8e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMR74213.1 - 4.4e-07 29.3 0.1 5.9e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMR74213.1 - 7.4e-07 29.2 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase_Csub PF13950.1 EMR74213.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Ldh_1_N PF00056.18 EMR74213.1 - 0.00039 20.2 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMR74213.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 EMR74213.1 - 0.02 14.5 0.0 0.077 12.6 0.0 1.9 1 1 0 1 1 1 0 KR domain AMP-binding PF00501.23 EMR74214.1 - 8.1e-88 294.6 0.0 1.1e-87 294.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EMR74214.1 - 4.8e-21 76.0 0.0 9.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.1 EMR74214.1 - 6.3e-13 49.4 0.2 1.2e-12 48.5 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EMR74214.1 - 2.4e-08 34.1 0.0 8.1e-08 32.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site RTX_C PF08339.5 EMR74214.1 - 0.0018 17.9 0.0 0.0059 16.3 0.0 1.9 1 0 0 1 1 1 1 RTX C-terminal domain ACPS PF01648.15 EMR74215.1 - 1.7e-15 56.8 0.4 3.6e-13 49.3 0.0 2.8 2 1 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily DUF1947 PF09183.5 EMR74215.1 - 0.45 10.3 3.9 0.31 10.8 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1947) HSA PF07529.8 EMR74215.1 - 2.7 7.8 8.7 9.7 6.0 1.0 2.5 2 0 0 2 2 2 0 HSA RNHCP PF12647.2 EMR74216.1 - 0.056 13.2 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 RNHCP domain zf-FPG_IleRS PF06827.9 EMR74216.1 - 0.091 12.4 2.1 4.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.2 EMR74216.1 - 0.16 11.8 3.5 1.9 8.3 2.4 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EMR74216.1 - 2.1 7.7 6.4 2.4 7.5 0.4 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding CtaG_Cox11 PF04442.9 EMR74217.1 - 0.019 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF11 PF01345.13 EMR74218.1 - 0.2 11.7 4.0 35 4.5 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF11 CAP_N PF01213.14 EMR74218.1 - 0.34 10.1 1.9 0.43 9.8 1.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Phytoreo_P8 PF07124.6 EMR74221.1 - 0.0075 14.9 0.9 0.01 14.5 0.6 1.2 1 0 0 1 1 1 1 Phytoreovirus outer capsid protein P8 DUF1049 PF06305.6 EMR74221.1 - 0.081 12.4 0.8 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CARDB PF07705.6 EMR74221.1 - 0.083 12.9 0.8 0.58 10.2 0.2 2.5 1 1 0 1 1 1 0 CARDB CAP_N PF01213.14 EMR74222.1 - 0.091 12.0 1.4 0.12 11.6 1.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-ribbon_3 PF13248.1 EMR74223.1 - 0.00047 19.2 0.6 0.00088 18.4 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Peptidase_M16_C PF05193.16 EMR74223.1 - 0.035 13.7 0.3 0.058 13.0 0.2 1.3 1 0 0 1 1 1 0 Peptidase M16 inactive domain Miro PF08477.8 EMR74223.1 - 0.089 13.2 0.1 0.4 11.2 0.1 2.0 2 0 0 2 2 2 0 Miro-like protein zinc_ribbon_2 PF13240.1 EMR74223.1 - 0.14 11.6 3.3 13 5.4 1.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EMR74223.1 - 0.54 9.6 4.7 0.32 10.3 1.4 2.1 2 1 0 2 2 2 0 TFIIB zinc-binding DUF1610 PF07754.6 EMR74223.1 - 1 9.5 5.3 22 5.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) CorA PF01544.13 EMR74223.1 - 1.6 7.7 6.8 2.9 6.8 3.8 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HALZ PF02183.13 EMR74223.1 - 2 8.1 5.5 0.56 9.9 1.6 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rubrerythrin PF02915.12 EMR74224.1 - 2.3e-29 102.4 6.7 2.9e-29 102.1 4.7 1.1 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.19 EMR74224.1 - 1e-08 35.0 1.8 1.3e-08 34.7 1.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF4379 PF14311.1 EMR74224.1 - 0.056 13.2 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) zf-like PF04071.7 EMR74224.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain RNA_POL_M_15KD PF02150.11 EMR74224.1 - 0.059 13.0 0.3 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DUF2296 PF10058.4 EMR74224.1 - 0.095 12.4 0.3 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Ferritin_2 PF13668.1 EMR74224.1 - 0.11 12.4 2.6 2.2 8.2 1.7 2.1 1 1 1 2 2 2 0 Ferritin-like domain Response_reg PF00072.19 EMR74230.1 - 8.5e-23 80.4 2.5 9.8e-23 80.3 1.8 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HAD PF12710.2 EMR74230.1 - 0.083 13.0 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_trans_4_2 PF13477.1 EMR74230.1 - 0.11 12.3 0.2 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like Peptidase_C11 PF03415.9 EMR74231.1 - 1.6e-39 136.0 0.5 2.6e-39 135.3 0.3 1.2 1 0 0 1 1 1 1 Clostripain family SPOR PF05036.8 EMR74232.1 - 0.024 14.7 0.5 0.028 14.5 0.4 1.2 1 0 0 1 1 1 0 Sporulation related domain PGK PF00162.14 EMR74233.1 - 9.6e-34 116.5 0.0 1.3e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase WWE PF02825.15 EMR74233.1 - 0.13 11.6 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 WWE domain DUF1516 PF07457.6 EMR74234.1 - 0.042 13.9 3.9 0.051 13.6 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) TMEM154 PF15102.1 EMR74234.1 - 0.053 13.2 1.6 0.057 13.1 1.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF1434 PF07254.7 EMR74234.1 - 0.2 11.4 1.5 0.24 11.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1434) DUF2207 PF09972.4 EMR74234.1 - 0.96 7.9 4.8 1.1 7.7 3.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3043 PF11241.3 EMR74234.1 - 1.9 8.0 4.9 1.9 8.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FokI_N PF02981.10 EMR74235.1 - 0.07 12.7 0.2 0.079 12.5 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain HTH_45 PF14947.1 EMR74236.1 - 4.4e-11 42.4 2.7 5.8e-11 42.0 1.9 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 EMR74236.1 - 2.6e-05 23.8 0.1 6.7e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HxlR PF01638.12 EMR74236.1 - 0.00014 21.4 0.1 0.00018 21.0 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix DUF2250 PF10007.4 EMR74236.1 - 0.00034 20.4 1.0 0.0042 16.9 0.7 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_24 PF13412.1 EMR74236.1 - 0.00053 19.3 0.2 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.8 EMR74236.1 - 0.0074 15.6 0.1 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_43 PF09904.4 EMR74236.1 - 0.014 15.2 0.1 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_5 PF01022.15 EMR74236.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_9 PF08221.6 EMR74236.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2853 PF11015.3 EMR74236.1 - 0.12 12.8 0.1 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) Rrf2 PF02082.15 EMR74236.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_45 PF14947.1 EMR74237.1 - 4e-09 36.1 0.3 5.9e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix HxlR PF01638.12 EMR74237.1 - 0.0061 16.1 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix DUF1188 PF06690.6 EMR74237.1 - 0.015 14.4 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Peptidase_M44 PF03410.8 EMR74237.1 - 0.067 11.4 0.0 0.074 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein G1 MCR_D PF02505.9 EMR74237.1 - 0.073 12.6 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D Nse4_C PF08743.5 EMR74238.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Nse4 C-terminal HTH_45 PF14947.1 EMR74239.1 - 5.3e-19 67.8 2.9 6.2e-19 67.6 2.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix RNA_pol_Rpc34 PF05158.7 EMR74239.1 - 0.035 13.2 1.5 0.039 13.1 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit ABC2_membrane_3 PF12698.2 EMR74241.1 - 0.04 12.9 3.2 0.052 12.5 2.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Caleosin PF05042.8 EMR74241.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Caleosin related protein DUF4129 PF13559.1 EMR74241.1 - 0.093 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) TF_Zn_Ribbon PF08271.7 EMR74242.1 - 0.0026 17.0 0.4 0.29 10.4 0.0 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EMR74242.1 - 0.0065 15.9 1.1 0.79 9.2 0.0 2.3 2 0 0 2 2 2 1 A2L zinc ribbon domain ADK_lid PF05191.9 EMR74242.1 - 0.015 14.9 0.3 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.1 EMR74242.1 - 0.016 14.9 0.3 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMR74242.1 - 0.017 14.7 0.2 5.2 6.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.1 EMR74242.1 - 0.019 15.0 0.4 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DNA_RNApol_7kD PF03604.8 EMR74242.1 - 0.028 13.8 4.9 0.5 9.8 0.2 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-DNA_Pol PF08996.5 EMR74242.1 - 0.033 13.5 1.1 0.039 13.3 0.7 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DZR PF12773.2 EMR74242.1 - 0.037 13.8 1.4 0.15 11.9 1.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon Rubredoxin PF00301.15 EMR74242.1 - 0.04 13.7 2.1 4.5 7.2 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin Lar_restr_allev PF14354.1 EMR74242.1 - 0.066 13.5 0.1 0.09 13.0 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EMR74242.1 - 0.077 12.2 1.8 0.22 10.7 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EMR74242.1 - 0.082 12.6 1.0 0.12 12.1 0.7 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EMR74242.1 - 0.13 12.0 2.6 0.75 9.6 1.7 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_L32p PF01783.18 EMR74242.1 - 0.16 12.1 2.1 8.9 6.5 0.1 2.3 1 1 1 2 2 2 0 Ribosomal L32p protein family zinc_ribbon_2 PF13240.1 EMR74242.1 - 0.2 11.2 2.5 0.57 9.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.1 EMR74242.1 - 0.2 11.6 1.6 7.5 6.5 1.1 2.1 1 1 1 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.5 EMR74242.1 - 0.22 11.5 2.0 2.8 7.9 0.2 2.3 2 1 0 2 2 2 0 Zinc ribbon domain DUF1610 PF07754.6 EMR74242.1 - 0.24 11.5 0.5 0.24 11.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.1 EMR74242.1 - 0.25 11.6 1.7 3.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain UPF0547 PF10571.4 EMR74242.1 - 0.33 10.6 5.8 3.6 7.3 1.2 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-AN1 PF01428.11 EMR74242.1 - 0.52 10.2 2.5 6 6.8 0.1 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Prok-RING_1 PF14446.1 EMR74242.1 - 0.58 9.9 3.6 6 6.6 0.0 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Nudix_N_2 PF14803.1 EMR74242.1 - 0.62 9.7 3.9 7.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal Desulfoferrod_N PF06397.7 EMR74242.1 - 0.97 8.8 4.5 0.98 8.8 0.3 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-BED PF02892.10 EMR74242.1 - 1.5 8.6 4.0 0.68 9.7 0.3 2.0 2 0 0 2 2 2 0 BED zinc finger zf-ribbon_3 PF13248.1 EMR74243.1 - 0.017 14.2 0.1 0.037 13.2 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EMR74243.1 - 0.063 12.9 1.5 7.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal DUF1272 PF06906.6 EMR74243.1 - 0.066 13.0 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Spt4 PF06093.8 EMR74243.1 - 0.08 12.8 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DZR PF12773.2 EMR74243.1 - 0.095 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.2 EMR74243.1 - 0.31 11.0 1.8 11 6.0 0.2 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Auto_anti-p27 PF06677.7 EMR74243.1 - 0.45 10.3 2.3 0.83 9.4 1.6 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.7 EMR74243.1 - 2.3 7.6 5.4 1 8.7 1.8 2.0 2 1 0 2 2 2 0 TFIIB zinc-binding Transglut_core PF01841.14 EMR74245.1 - 1.6e-12 47.6 0.0 3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 EMR74245.1 - 0.019 14.3 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Laminin_G_3 PF13385.1 EMR74263.1 - 6.1e-23 81.7 0.3 6.1e-23 81.7 0.2 2.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Nitrophorin PF02087.10 EMR74263.1 - 0.021 14.6 0.3 0.044 13.5 0.2 1.5 1 0 0 1 1 1 0 Nitrophorin Cellulase-like PF12876.2 EMR74263.1 - 0.035 14.5 0.1 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Sugar-binding cellulase-like Glyco_hydro_39 PF01229.12 EMR74263.1 - 0.082 11.2 1.5 0.35 9.1 1.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 39 Glycos_transf_1 PF00534.15 EMR74267.1 - 1.9e-25 89.2 0.0 3e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMR74267.1 - 4.4e-22 78.6 0.0 6.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EMR74267.1 - 7.1e-14 52.2 0.0 1.1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EMR74267.1 - 2.7e-10 40.5 0.0 6.2e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EMR74267.1 - 9e-07 28.8 2.0 1.6e-06 27.9 0.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.6 EMR74267.1 - 3e-05 23.6 0.2 0.048 13.1 0.2 2.3 1 1 1 2 2 2 2 Starch synthase catalytic domain Asp_protease_2 PF13650.1 EMR74270.1 - 6.8e-06 26.4 0.0 2.9e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EMR74270.1 - 5.2e-05 22.9 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp PF00026.18 EMR74270.1 - 0.06 12.5 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Ribosomal_S5_C PF03719.10 EMR74271.1 - 0.0089 15.2 0.0 0.0099 15.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Cauli_VI PF01693.11 EMR74271.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Caulimovirus viroplasmin KH_2 PF07650.12 EMR74273.1 - 0.027 14.0 0.2 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 KH domain PadR PF03551.9 EMR74275.1 - 2e-10 40.2 0.2 7e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HemN_C PF06969.11 EMR74275.1 - 0.002 18.1 0.9 0.091 12.8 0.0 2.4 2 0 0 2 2 2 1 HemN C-terminal domain HTH_45 PF14947.1 EMR74275.1 - 0.0034 17.1 1.4 0.012 15.4 0.0 2.3 2 1 1 3 3 3 1 Winged helix-turn-helix Nitroreductase PF00881.19 EMR74276.1 - 1.8e-13 50.6 0.1 1.8e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 Nitroreductase family HTH_45 PF14947.1 EMR74278.1 - 0.12 12.1 1.0 0.96 9.3 0.0 2.5 2 1 1 3 3 3 0 Winged helix-turn-helix Caveolin PF01146.12 EMR74281.1 - 0.063 12.8 0.1 0.079 12.5 0.1 1.2 1 0 0 1 1 1 0 Caveolin tRNA_NucTransf2 PF09249.6 EMR74291.1 - 1.1e-40 138.1 0.0 1.5e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain eIF-1a PF01176.14 EMR74291.1 - 0.11 11.8 0.0 0.36 10.2 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Phage_integrase PF00589.17 EMR74293.1 - 1.6e-23 83.2 1.2 2e-23 82.9 0.2 1.6 2 0 0 2 2 2 1 Phage integrase family HTH_23 PF13384.1 EMR74295.1 - 0.019 14.5 0.1 0.033 13.8 0.0 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EMR74295.1 - 0.021 14.2 0.1 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.1 EMR74295.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain PMBR PF09373.5 EMR74296.1 - 0.0025 17.6 0.1 0.0093 15.8 0.1 2.1 1 0 0 1 1 1 1 Pseudomurein-binding repeat HTH_24 PF13412.1 EMR74296.1 - 0.015 14.6 0.2 0.037 13.4 0.2 1.8 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EMR74297.1 - 0.0014 18.3 0.0 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 EMR74297.1 - 0.0051 16.3 0.1 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.17 EMR74297.1 - 0.0052 16.4 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.1 EMR74297.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_23 PF13384.1 EMR74297.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain MerR_1 PF13411.1 EMR74297.1 - 0.092 12.5 0.7 0.33 10.7 0.5 1.9 1 1 0 1 1 1 0 MerR HTH family regulatory protein DUF2172 PF09940.4 EMR74297.1 - 0.097 11.0 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) HTH_Tnp_4 PF13613.1 EMR74297.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_5 PF01022.15 EMR74297.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF3472 PF11958.3 EMR74299.1 - 4.8e-09 36.8 0.1 2.3e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) DUF849 PF05853.7 EMR74307.1 - 3.2e-24 85.2 0.7 1.1e-23 83.5 0.5 1.7 1 1 0 1 1 1 1 Prokaryotic protein of unknown function (DUF849) zf-ribbon_3 PF13248.1 EMR74311.1 - 0.03 13.5 1.4 0.067 12.4 1.0 1.6 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EMR74311.1 - 0.076 12.8 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EMR74311.1 - 0.099 12.1 2.3 0.16 11.4 1.6 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 EMR74311.1 - 0.4 10.2 3.9 4.3 6.9 2.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain SIMPL PF04402.9 EMR74313.1 - 5.2e-44 150.6 3.4 6.1e-44 150.3 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) adh_short PF00106.20 EMR74314.1 - 4e-24 85.3 0.0 5.8e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR74314.1 - 1.3e-21 77.5 0.0 1.6e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR74314.1 - 1.5e-07 31.2 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Bac_luciferase PF00296.15 EMR74315.1 - 1.8e-54 184.9 0.0 3e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Abi PF02517.11 EMR74317.1 - 2.4e-06 27.5 11.7 2.4e-06 27.5 8.1 3.4 1 1 2 3 3 3 1 CAAX protease self-immunity DPM2 PF07297.7 EMR74317.1 - 9.5 6.5 12.6 0.31 11.3 0.9 3.2 3 0 0 3 3 3 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) ParBc PF02195.13 EMR74318.1 - 4.3e-19 68.3 0.0 7.8e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain DUF488 PF04343.8 EMR74318.1 - 1.1e-15 58.0 0.1 2.7e-15 56.8 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function, DUF488 HTH_37 PF13744.1 EMR74318.1 - 5.7e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EMR74318.1 - 0.0006 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 KorB PF08535.5 EMR74318.1 - 0.00099 19.2 0.0 0.0027 17.8 0.0 1.8 1 1 0 1 1 1 1 KorB domain Phage_CI_repr PF07022.8 EMR74318.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_23 PF13384.1 EMR74318.1 - 0.0021 17.6 0.0 0.0064 16.1 0.0 1.8 1 1 1 2 2 2 1 Homeodomain-like domain DUF222 PF02720.12 EMR74318.1 - 0.0032 16.6 0.1 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HTH_31 PF13560.1 EMR74318.1 - 0.0044 17.1 0.0 0.0088 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_ECF PF07638.6 EMR74318.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_8 PF02954.14 EMR74318.1 - 0.0088 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Y_phosphatase3 PF13350.1 EMR74318.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family MarR_2 PF12802.2 EMR74318.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.1 EMR74318.1 - 0.044 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain G-patch PF01585.18 EMR74318.1 - 0.18 11.5 1.3 1 9.1 0.4 2.2 2 0 0 2 2 2 0 G-patch domain Lactamase_B PF00753.22 EMR74320.1 - 1.1e-23 83.9 0.6 1.3e-23 83.6 0.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR74320.1 - 4.6e-05 23.0 0.2 0.0004 19.9 0.1 2.0 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR74320.1 - 0.05 13.2 0.0 0.063 12.9 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Methyltransf_18 PF12847.2 EMR74322.1 - 6.1e-08 33.2 0.0 8.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EMR74322.1 - 6.1e-07 28.9 0.0 1.4e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EMR74322.1 - 5.5e-06 26.3 0.0 8.7e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR74322.1 - 9.6e-06 24.8 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EMR74322.1 - 0.0026 17.3 0.0 0.0037 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMR74322.1 - 0.003 17.1 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EMR74322.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_4 PF02390.12 EMR74322.1 - 0.019 14.0 0.0 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EMR74322.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Acetyltransf_10 PF13673.1 EMR74322.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RrnaAD PF00398.15 EMR74322.1 - 0.056 12.4 0.0 0.096 11.6 0.0 1.3 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 EMR74322.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Acetyltransf_1 PF00583.19 EMR74322.1 - 0.068 13.2 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family B12-binding PF02310.14 EMR74324.1 - 8e-19 67.6 1.4 1.2e-18 67.1 1.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.12 EMR74324.1 - 2.9e-12 46.4 0.0 5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain DNAPolymera_Pol PF11590.3 EMR74324.1 - 0.056 13.1 0.1 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol DUF2642 PF10842.3 EMR74324.1 - 0.078 12.4 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) BMC PF00936.14 EMR74324.1 - 1.9 8.2 8.0 0.73 9.5 2.3 2.6 2 1 1 3 3 3 0 BMC domain URO-D PF01208.12 EMR74325.1 - 1.4e-26 93.2 0.0 2.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Acetyltransf_7 PF13508.1 EMR74326.1 - 1.9e-05 24.7 0.4 0.2 11.8 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR74326.1 - 4.7e-05 23.2 0.1 0.0067 16.2 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR74326.1 - 0.012 15.6 0.0 1.6 8.8 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family