# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Cdc6_C PF09079.6 AIF82085.1 - 5.6e-09 35.6 0.1 1.9e-08 33.9 0.1 1.9 1 0 0 1 1 1 1 CDC6, C terminal AAA_16 PF13191.1 AIF82085.1 - 1.1e-08 35.3 2.3 3.2e-07 30.5 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AIF82085.1 - 1.5e-07 31.6 0.1 6.2e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 AIF82085.1 - 4.2e-07 30.2 0.0 1.3e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AIF82085.1 - 5.3e-06 26.2 0.1 0.079 12.6 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase AAA_17 PF13207.1 AIF82085.1 - 1.8e-05 25.5 0.1 4.1e-05 24.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 AIF82085.1 - 0.00042 20.0 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_25 PF13481.1 AIF82085.1 - 0.00055 19.3 1.1 0.67 9.3 0.0 3.0 2 1 1 3 3 3 2 AAA domain RNA_helicase PF00910.17 AIF82085.1 - 0.013 15.6 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 AIF82085.1 - 0.014 14.9 0.0 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 AIF82085.1 - 0.014 15.2 0.0 0.044 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AIF82085.1 - 0.019 14.3 0.1 0.07 12.5 0.0 1.9 2 1 1 3 3 3 0 AAA-like domain AAA_29 PF13555.1 AIF82085.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 AIF82085.1 - 0.043 13.1 0.1 10 5.4 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase ABC_tran PF00005.22 AIF82085.1 - 0.043 14.1 0.2 0.34 11.2 0.0 2.5 2 2 2 4 4 3 0 ABC transporter CBFD_NFYB_HMF PF00808.18 AIF82085.1 - 0.049 13.7 0.0 3.7 7.6 0.0 3.3 2 1 1 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3987 PF13148.1 AIF82085.1 - 0.053 12.0 0.0 0.053 12.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) DUF815 PF05673.8 AIF82085.1 - 0.055 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 AIF82085.1 - 0.055 12.3 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain SMC_N PF02463.14 AIF82085.1 - 0.1 11.7 0.1 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 AIF82085.1 - 0.11 12.2 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AIF82085.1 - 0.13 12.5 0.5 0.4 10.9 0.0 2.2 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 AIF82085.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 NTPase Folliculin PF11704.3 AIF82087.1 - 0.063 12.8 0.3 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport IncFII_repA PF02387.10 AIF82087.1 - 0.53 9.3 5.6 0.45 9.6 1.0 2.1 1 1 1 2 2 2 0 IncFII RepA protein family Rad51 PF08423.6 AIF82088.1 - 1.5e-09 37.1 0.0 2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 AIF82088.1 - 0.028 13.5 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 KaiC RNA_POL_M_15KD PF02150.11 AIF82088.1 - 0.062 12.9 5.5 0.19 11.4 0.5 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 AIF82088.1 - 0.2 11.1 4.7 0.62 9.6 0.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF82088.1 - 0.4 9.9 3.4 0.75 9.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.7 AIF82088.1 - 4 7.5 5.2 10 6.2 1.3 2.2 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DNA_pol_B PF00136.16 AIF82091.1 - 2.3e-40 138.7 0.0 3.7e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AIF82091.1 - 1.4e-10 40.5 0.0 8.6e-09 34.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain IL1 PF00340.14 AIF82091.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin-1 / 18 Methyltransf_3 PF01596.12 AIF82092.1 - 6.6e-36 123.2 0.0 7.9e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 AIF82092.1 - 3.3e-17 63.2 0.0 5.2e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF82092.1 - 3.2e-12 46.3 0.0 4.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF82092.1 - 4.3e-11 43.3 0.1 6.2e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF82092.1 - 1.2e-10 41.4 0.1 5.3e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AIF82092.1 - 4.8e-08 32.7 0.0 7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CmcI PF04989.7 AIF82092.1 - 5.2e-06 25.9 0.0 7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase MTS PF05175.9 AIF82092.1 - 7.4e-06 25.4 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 AIF82092.1 - 3.7e-05 24.1 0.0 7.9e-05 23.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain GCD14 PF08704.5 AIF82092.1 - 0.0002 20.9 0.0 0.00027 20.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.1 AIF82092.1 - 0.00077 19.7 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AIF82092.1 - 0.0074 15.4 0.1 0.01 14.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 AIF82092.1 - 0.0094 15.0 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.10 AIF82092.1 - 0.018 14.4 0.1 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MetW PF07021.7 AIF82092.1 - 0.018 14.3 0.1 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.5 AIF82092.1 - 0.02 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 AIF82092.1 - 0.081 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.21 AIF82092.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 AIF82092.1 - 0.14 12.6 0.1 0.32 11.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain OTCace_N PF02729.16 AIF82093.1 - 2.9e-42 143.6 0.0 5.3e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AIF82093.1 - 2.2e-37 128.3 0.0 3.1e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF1801 PF08818.6 AIF82094.1 - 7.6e-06 25.9 0.0 9.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DU1801) MSV199 PF10553.4 AIF82096.1 - 0.039 13.8 0.4 0.041 13.7 0.3 1.0 1 0 0 1 1 1 0 MSV199 domain F420_oxidored PF03807.12 AIF82097.1 - 1.1e-14 54.6 0.1 1.5e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AIF82097.1 - 8.8e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 AIF82097.1 - 0.00086 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 AIF82097.1 - 0.0029 17.2 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AIF82097.1 - 0.0062 15.9 0.0 0.072 12.5 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 AIF82097.1 - 0.0093 15.3 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 AIF82097.1 - 0.019 14.9 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Rossmann-like PF10727.4 AIF82097.1 - 0.035 13.8 0.0 0.31 10.7 0.0 2.3 3 0 0 3 3 3 0 Rossmann-like domain 2-Hacid_dh_C PF02826.14 AIF82097.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF347 PF03988.7 AIF82098.1 - 0.0068 16.2 0.2 0.0085 15.9 0.1 1.3 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Tim17 PF02466.14 AIF82098.1 - 0.095 12.7 1.9 0.11 12.5 1.3 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family NfeD PF01957.13 AIF82098.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding LHC PF00556.15 AIF82098.1 - 0.65 9.8 4.6 1.1 9.1 3.2 1.4 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit eIF-6 PF01912.13 AIF82099.1 - 1.9e-66 222.9 0.2 2.3e-66 222.6 0.2 1.1 1 0 0 1 1 1 1 eIF-6 family MoCF_biosynth PF00994.19 AIF82100.1 - 5.3e-35 119.9 0.1 7.1e-35 119.5 0.1 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain COesterase PF00135.23 AIF82101.1 - 0.15 10.7 0.3 0.17 10.5 0.2 1.0 1 0 0 1 1 1 0 Carboxylesterase family Aminotran_4 PF01063.14 AIF82102.1 - 2.7e-47 161.1 0.0 3.2e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV DUF3944 PF13099.1 AIF82102.1 - 0.13 11.7 1.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) AA_kinase PF00696.23 AIF82103.1 - 8e-24 84.5 0.4 1.4e-23 83.6 0.3 1.4 1 0 0 1 1 1 1 Amino acid kinase family C1_1 PF00130.17 AIF82105.1 - 0.0067 16.1 0.7 0.0078 15.9 0.5 1.1 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 AIF82105.1 - 0.011 15.2 3.5 0.7 9.4 0.3 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_L37e PF01907.14 AIF82105.1 - 0.033 13.9 0.4 0.045 13.5 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L37e TF_Zn_Ribbon PF08271.7 AIF82105.1 - 0.041 13.2 2.3 1.6 8.1 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-IS66 PF13005.2 AIF82105.1 - 0.043 13.8 5.2 0.11 12.4 0.2 2.2 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 Desulfoferrod_N PF06397.7 AIF82105.1 - 0.053 12.9 0.7 0.053 12.9 0.5 2.0 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DZR PF12773.2 AIF82105.1 - 0.053 13.3 1.1 0.15 11.9 0.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 AIF82105.1 - 0.071 13.0 2.5 2.5 8.1 0.4 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS91 PF14319.1 AIF82105.1 - 0.11 11.9 0.9 0.14 11.6 0.6 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-NADH-PPase PF09297.6 AIF82105.1 - 0.12 11.9 2.6 3.8 7.0 0.4 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_L37ae PF01780.14 AIF82105.1 - 0.13 12.0 0.4 0.15 11.9 0.3 1.0 1 0 0 1 1 1 0 Ribosomal L37ae protein family Rubredoxin PF00301.15 AIF82105.1 - 0.14 12.0 1.4 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Rubredoxin zf-H2C2_2 PF13465.1 AIF82105.1 - 0.16 12.2 0.4 0.32 11.3 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 AIF82105.1 - 0.19 11.5 1.6 0.28 11.0 1.1 1.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 AIF82105.1 - 0.35 10.9 1.9 0.39 10.7 0.1 1.8 2 0 0 2 2 2 0 zinc-finger TFIIS_C PF01096.13 AIF82105.1 - 0.37 10.4 1.8 2.8 7.6 0.3 2.0 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) ZZ PF00569.12 AIF82105.1 - 0.42 10.1 3.2 5.7 6.5 0.1 2.1 1 1 1 2 2 2 0 Zinc finger, ZZ type zf-ISL3 PF14690.1 AIF82105.1 - 0.71 9.9 4.0 4 7.5 0.1 2.1 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Fer4 PF00037.22 AIF82105.1 - 1.8 8.2 5.1 0.61 9.7 0.4 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain zf-TFIIB PF13453.1 AIF82105.1 - 6.3 6.0 6.0 1e+02 2.1 4.1 2.1 1 1 0 1 1 1 0 Transcription factor zinc-finger HTH_20 PF12840.2 AIF82106.1 - 1.5e-05 24.7 0.1 3.2e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_45 PF14947.1 AIF82106.1 - 1.7e-05 24.5 0.1 3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DUF1724 PF08350.5 AIF82106.1 - 0.00022 20.6 0.0 0.00056 19.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1724) HTH_24 PF13412.1 AIF82106.1 - 0.0005 19.4 0.3 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF4423 PF14394.1 AIF82106.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR_2 PF12802.2 AIF82106.1 - 0.0078 15.8 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.15 AIF82106.1 - 0.024 14.2 0.1 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR PF01047.17 AIF82106.1 - 0.032 13.9 0.1 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.1 AIF82106.1 - 0.033 14.2 0.1 0.19 11.8 0.0 2.2 3 0 0 3 3 3 0 Winged helix DNA-binding domain TrmB PF01978.14 AIF82106.1 - 0.041 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 AIF82106.1 - 0.073 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain SnoaL_2 PF12680.2 AIF82108.1 - 2e-31 108.3 0.0 1.6e-19 70.2 0.1 2.1 2 0 0 2 2 2 2 SnoaL-like domain SnoaL PF07366.7 AIF82108.1 - 1.5e-29 102.1 0.0 3.6e-25 87.9 0.0 3.1 3 0 0 3 3 3 3 SnoaL-like polyketide cyclase LEH PF07858.7 AIF82108.1 - 6.5e-09 35.8 0.1 0.0012 18.8 0.0 3.6 3 1 0 3 3 3 2 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_3 PF13474.1 AIF82108.1 - 1.5e-06 28.2 0.0 0.03 14.3 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.1 AIF82108.1 - 2e-05 24.7 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4440) Lumazine_bd PF12870.2 AIF82108.1 - 0.00087 19.3 0.1 0.0072 16.3 0.0 2.1 2 0 0 2 2 2 1 Lumazine-binding domain Kelch_1 PF01344.20 AIF82109.1 - 4.6e-70 230.9 0.0 1.9e-13 49.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 AIF82109.1 - 7.3e-54 177.8 3.8 7.9e-10 38.4 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.10 AIF82109.1 - 5.1e-38 127.4 0.0 1.4e-05 24.6 0.0 6.8 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 AIF82109.1 - 1.5e-37 127.1 0.6 1.4e-06 27.9 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 AIF82109.1 - 2.3e-33 113.5 12.2 9.5e-08 32.0 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 AIF82109.1 - 1.1e-29 101.8 5.0 0.00015 21.6 0.0 6.2 6 0 0 6 6 6 5 Kelch motif DUF1668 PF07893.8 AIF82109.1 - 0.00019 20.7 0.1 0.2 10.7 0.0 3.0 1 1 3 4 4 4 3 Protein of unknown function (DUF1668) PQQ_3 PF13570.1 AIF82109.1 - 0.0003 20.9 7.1 0.3 11.4 0.1 5.6 6 0 0 6 6 6 1 PQQ-like domain Rax2 PF12768.2 AIF82109.1 - 0.16 11.1 0.0 1.4 8.1 0.0 2.4 2 1 0 2 2 2 0 Cortical protein marker for cell polarity ADH_zinc_N PF00107.21 AIF82110.1 - 1.2e-19 70.1 0.0 4.3e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIF82110.1 - 0.00025 21.9 0.0 0.00044 21.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Adeno_E3_CR2 PF02439.10 AIF82112.1 - 0.52 9.9 2.2 1 8.9 1.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glyco_trans_1_3 PF13528.1 AIF82114.1 - 1.1e-11 44.4 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 AIF82114.1 - 2.7e-11 43.4 0.0 4.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.1 AIF82114.1 - 0.028 14.5 0.0 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 NikR_C PF08753.6 AIF82115.1 - 5.5e-13 48.6 4.7 5.8e-13 48.5 2.6 1.5 2 0 0 2 2 2 1 NikR C terminal nickel binding domain RHH_1 PF01402.16 AIF82115.1 - 0.00041 20.1 0.1 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF2191 PF09957.4 AIF82115.1 - 0.05 13.4 1.0 0.12 12.2 0.7 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2191) DUF4347 PF14252.1 AIF82115.1 - 0.073 12.5 0.1 0.15 11.5 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4347) TroA PF01297.12 AIF82116.1 - 8.2e-75 251.3 0.0 9.9e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic solute binding protein family DUF3366 PF11846.3 AIF82116.1 - 0.062 13.1 0.2 8.8 6.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) DUF2964 PF11177.3 AIF82116.1 - 0.09 12.7 0.3 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) ABC_tran PF00005.22 AIF82117.1 - 3e-32 111.7 0.2 2.7e-31 108.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AIF82117.1 - 1.3e-14 54.8 1.0 2.5e-13 50.6 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 AIF82117.1 - 8.8e-06 25.0 0.7 0.00094 18.3 0.4 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AIF82117.1 - 2.2e-05 24.8 1.9 3.4e-05 24.2 1.3 1.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AIF82117.1 - 0.00015 21.0 0.9 0.0016 17.7 0.6 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AIF82117.1 - 0.0069 15.8 1.6 0.011 15.2 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 AIF82117.1 - 0.0095 15.8 0.0 0.051 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AIF82117.1 - 0.0099 15.3 0.3 0.02 14.3 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain SbcCD_C PF13558.1 AIF82117.1 - 0.017 15.0 0.2 1 9.3 0.1 2.8 1 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.16 AIF82117.1 - 0.018 14.2 0.1 0.27 10.3 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 AIF82117.1 - 0.019 15.1 1.5 0.46 10.6 1.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AIF82117.1 - 0.033 13.6 0.6 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 AIF82117.1 - 0.059 12.4 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC-3 PF00950.12 AIF82118.1 - 6.1e-67 225.6 36.4 7e-67 225.4 25.2 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.13 AIF82118.1 - 2.3e-05 23.3 38.3 0.0001 21.2 26.6 1.9 1 1 0 1 1 1 1 FecCD transport family DUF677 PF05055.7 AIF82118.1 - 9.7 4.7 6.6 7 5.2 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF677) MarR_2 PF12802.2 AIF82119.1 - 2.7e-05 23.7 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 MarR family DUF4271 PF14093.1 AIF82119.1 - 0.0039 16.8 0.1 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) HTH_45 PF14947.1 AIF82119.1 - 0.053 13.3 0.6 0.11 12.3 0.4 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix ATP-synt_A PF00119.15 AIF82119.1 - 0.061 12.8 0.6 0.084 12.3 0.4 1.1 1 0 0 1 1 1 0 ATP synthase A chain NUDIX PF00293.23 AIF82120.1 - 1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain zf-B_box PF00643.19 AIF82121.1 - 0.0042 16.9 6.9 0.0042 16.9 4.8 2.0 2 0 0 2 2 2 1 B-box zinc finger C6_DPF PF10170.4 AIF82121.1 - 0.037 14.0 4.6 0.028 14.4 2.6 1.3 1 1 0 1 1 1 0 Cysteine-rich domain Siva PF05458.7 AIF82121.1 - 0.086 12.4 4.2 0.089 12.3 2.9 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.11 AIF82121.1 - 0.33 10.8 8.9 0.58 10.0 6.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.1 AIF82121.1 - 0.5 10.0 11.4 0.92 9.2 7.9 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sgf11 PF08209.6 AIF82121.1 - 0.71 9.2 9.1 0.76 9.1 0.1 3.1 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) DZR PF12773.2 AIF82121.1 - 2.7 7.8 10.9 3.7 7.4 1.3 2.1 1 1 1 2 2 2 0 Double zinc ribbon Glyoxalase_2 PF12681.2 AIF82122.1 - 8.5e-14 52.0 0.0 9.8e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF82122.1 - 1.3e-06 28.3 0.2 7e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily N6_N4_Mtase PF01555.13 AIF82123.1 - 1.4e-22 80.3 0.2 8e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Dev_Cell_Death PF10539.4 AIF82123.1 - 5.6e-17 61.5 0.0 9.2e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain Methyltransf_26 PF13659.1 AIF82123.1 - 2.3e-10 40.5 0.1 8.1e-10 38.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AIF82123.1 - 3.4e-06 26.7 0.1 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 AIF82123.1 - 3.7e-06 27.3 0.1 9.7e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AIF82123.1 - 0.00012 21.8 0.1 0.00037 20.1 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase Cons_hypoth95 PF03602.10 AIF82123.1 - 0.066 12.6 0.0 3.8 6.8 0.1 2.3 1 1 1 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 AIF82123.1 - 0.15 11.8 0.0 0.74 9.5 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Neur_chan_memb PF02932.11 AIF82124.1 - 6.4e-07 29.5 4.4 6.4e-07 29.5 3.1 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 AIF82124.1 - 0.17 10.9 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel ligand binding domain 60KD_IMP PF02096.15 AIF82124.1 - 3.5 7.2 6.5 1.5 8.4 3.0 1.4 2 0 0 2 2 2 0 60Kd inner membrane protein PhoU PF01895.14 AIF82125.1 - 1.1e-23 83.4 7.4 7.9e-17 61.4 0.9 2.7 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 AIF82125.1 - 2.1e-05 24.1 0.0 6.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Antidote-toxin recognition MazE PhoU PF01895.14 AIF82126.1 - 1.1e-29 102.6 1.5 6.2e-18 65.0 0.2 2.1 2 0 0 2 2 2 2 PhoU domain Peptidase_M19 PF01244.16 AIF82126.1 - 0.023 13.6 0.2 0.045 12.6 0.0 1.5 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) DUF2034 PF10356.4 AIF82126.1 - 0.035 13.2 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DUF4200 PF13863.1 AIF82126.1 - 0.12 12.3 0.6 0.78 9.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ABC_tran PF00005.22 AIF82127.1 - 1.6e-30 106.1 0.0 2.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF82127.1 - 2.7e-14 53.8 0.1 4.7e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 AIF82127.1 - 6.7e-10 38.5 0.2 5.4e-09 35.6 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AIF82127.1 - 1.6e-05 24.9 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AIF82127.1 - 1.6e-05 25.0 0.1 0.0002 21.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AIF82127.1 - 5.9e-05 22.2 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 AIF82127.1 - 7e-05 22.0 0.4 0.28 10.1 0.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 AIF82127.1 - 0.0003 21.0 0.4 0.0044 17.2 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 AIF82127.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 AIF82127.1 - 0.0015 18.2 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 AIF82127.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 AIF82127.1 - 0.0033 16.1 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 AIF82127.1 - 0.0062 16.8 0.0 0.019 15.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AIF82127.1 - 0.0066 17.2 0.0 0.014 16.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.1 AIF82127.1 - 0.01 16.1 0.1 0.045 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 AIF82127.1 - 0.01 14.5 0.1 0.021 13.4 0.0 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein MobB PF03205.9 AIF82127.1 - 0.012 15.3 0.3 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AIF82127.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AIF82127.1 - 0.014 14.8 0.1 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 AIF82127.1 - 0.015 14.7 0.1 0.032 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 AIF82127.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AIF82127.1 - 0.024 14.3 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain ABC_ATPase PF09818.4 AIF82127.1 - 0.029 12.9 0.1 0.4 9.2 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.1 AIF82127.1 - 0.034 13.7 0.2 0.071 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AIF82127.1 - 0.038 13.8 0.0 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 AIF82127.1 - 0.042 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 AIF82127.1 - 0.052 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 AIF82127.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 AIF82127.1 - 0.063 12.7 0.2 0.2 11.1 0.1 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 AIF82127.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 AIF82127.1 - 0.1 12.1 0.4 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 AIF82127.1 - 0.13 11.7 0.5 0.27 10.6 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 AIF82127.1 - 0.13 11.6 0.1 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein BPD_transp_1 PF00528.17 AIF82128.1 - 6.9e-19 68.0 17.5 6.9e-19 68.0 12.1 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.3 AIF82128.1 - 0.0018 18.3 0.1 0.0018 18.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3333) COX14 PF14880.1 AIF82128.1 - 0.0073 15.9 0.0 0.026 14.1 0.0 2.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly BPD_transp_1 PF00528.17 AIF82129.1 - 2.2e-16 59.9 20.6 2.2e-16 59.9 14.3 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PBP_like_2 PF12849.2 AIF82130.1 - 1.5e-53 182.1 7.6 1.5e-53 182.1 5.3 1.6 2 0 0 2 2 2 1 PBP superfamily domain PBP_like PF12727.2 AIF82130.1 - 3.5e-10 39.1 0.0 1.2e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 PBP superfamily domain DUF3588 PF12140.3 AIF82130.1 - 0.034 14.2 0.2 0.084 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3588) Zn-ribbon_8 PF09723.5 AIF82132.1 - 0.043 13.7 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HNH PF01844.18 AIF82132.1 - 4.8 7.1 5.0 0.88 9.4 0.4 1.9 2 0 0 2 2 2 0 HNH endonuclease His_Phos_1 PF00300.17 AIF82133.1 - 3.8e-15 56.3 0.0 5.8e-13 49.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ppx-GppA PF02541.11 AIF82134.1 - 6.2e-51 173.2 0.0 1.1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Thymidylate_kin PF02223.12 AIF82135.1 - 5.6e-23 81.2 0.0 9.5e-23 80.5 0.0 1.4 1 1 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 AIF82135.1 - 0.00039 20.7 0.3 0.0034 17.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 AIF82135.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AIF82135.1 - 0.035 14.9 0.1 0.095 13.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIF82135.1 - 0.046 13.5 0.0 0.098 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 AIF82136.1 - 1.9e-20 73.0 0.0 2.7e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 AIF82136.1 - 0.00079 19.3 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIF82136.1 - 0.0083 16.9 0.2 0.47 11.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AIF82136.1 - 0.036 14.3 0.2 0.46 10.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain CHAD PF05235.9 AIF82137.1 - 6.2e-21 75.0 11.5 4.1e-19 69.0 6.7 1.9 1 1 1 2 2 2 2 CHAD domain RVT_3 PF13456.1 AIF82138.1 - 0.0017 18.1 0.1 0.0037 17.0 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 AIF82138.1 - 0.0097 16.2 0.1 0.033 14.5 0.0 1.9 1 1 1 2 2 2 1 RNase H HxlR PF01638.12 AIF82139.1 - 1.1e-22 79.4 0.2 1.3e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.1 AIF82139.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.9 AIF82139.1 - 0.00014 21.5 0.2 0.00021 21.0 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.2 AIF82139.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 AIF82139.1 - 0.046 13.1 0.1 0.087 12.2 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 AIF82139.1 - 0.091 12.5 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix Methyltransf_31 PF13847.1 AIF82140.1 - 1.6e-31 108.9 0.0 1.6e-31 108.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF82140.1 - 3.7e-20 72.2 0.8 5.9e-20 71.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF82140.1 - 1.2e-16 61.3 2.5 1.6e-16 60.8 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF82140.1 - 5.1e-14 51.9 0.4 9.2e-14 51.1 0.3 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AIF82140.1 - 5.2e-12 45.8 0.3 1.3e-11 44.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF82140.1 - 3.6e-11 43.3 2.3 4.5e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82140.1 - 5.2e-11 42.5 0.0 8.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF82140.1 - 2.2e-10 40.8 0.6 5e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 AIF82140.1 - 9.9e-10 38.2 0.1 1.7e-09 37.5 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AIF82140.1 - 1e-07 31.3 0.2 1.3e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AIF82140.1 - 2.7e-06 26.8 0.0 4.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 AIF82140.1 - 4.3e-06 26.0 0.0 5.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 AIF82140.1 - 3e-05 23.6 0.1 4.8e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 AIF82140.1 - 3.5e-05 23.5 0.1 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.13 AIF82140.1 - 9.3e-05 21.7 0.1 0.00016 20.9 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 AIF82140.1 - 0.00025 20.7 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AIF82140.1 - 0.0025 16.8 0.0 0.45 9.4 0.0 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family DOT1 PF08123.8 AIF82140.1 - 0.008 15.4 0.2 0.016 14.5 0.1 1.5 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_15 PF09445.5 AIF82140.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.1 AIF82140.1 - 0.018 15.8 0.1 0.045 14.5 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 AIF82140.1 - 0.02 13.6 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.11 AIF82140.1 - 0.071 11.4 0.0 0.09 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_3 PF01596.12 AIF82140.1 - 0.083 11.9 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase LMWPc PF01451.16 AIF82141.1 - 2.2e-27 96.0 0.0 3e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MIP PF00230.15 AIF82142.1 - 6.3e-34 117.4 20.3 7.9e-34 117.0 14.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Na_H_Exchanger PF00999.16 AIF82143.1 - 1.5e-63 214.6 54.1 1.8e-63 214.3 37.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.7 AIF82143.1 - 0.046 13.2 31.9 0.14 11.6 5.6 3.4 2 1 0 2 2 2 0 Predicted Permease Membrane Region DUF95 PF01944.12 AIF82144.1 - 1.4e-08 34.5 6.8 1.9e-08 34.1 4.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF95 ABM PF03992.11 AIF82145.1 - 4e-14 52.4 0.1 5.4e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase RNA12 PF10443.4 AIF82145.1 - 0.12 10.8 0.1 0.15 10.5 0.1 1.1 1 0 0 1 1 1 0 RNA12 protein Glycolipid_bind PF06475.6 AIF82148.1 - 1.2e-55 187.4 0.0 1.4e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Putative glycolipid-binding DZR PF12773.2 AIF82149.1 - 1.3e-05 24.8 3.4 1.6e-05 24.5 2.3 1.1 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF82149.1 - 1.7e-05 23.8 10.8 0.00025 20.1 3.9 1.8 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF82149.1 - 8.7e-05 21.8 4.5 0.00011 21.6 3.1 1.2 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.4 AIF82149.1 - 0.0011 18.6 3.6 0.0017 17.9 2.5 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.1 AIF82149.1 - 0.0044 16.6 1.9 0.0058 16.2 1.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.1 AIF82149.1 - 0.0054 16.5 7.4 0.11 12.3 0.4 2.3 1 1 1 2 2 2 2 YhfH-like protein DUF3279 PF11682.3 AIF82149.1 - 0.019 14.5 1.0 0.019 14.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) Opy2 PF09463.5 AIF82149.1 - 0.045 13.8 2.3 0.086 12.9 1.6 1.5 1 1 0 1 1 1 0 Opy2 protein zf-RING_2 PF13639.1 AIF82149.1 - 0.05 13.4 0.6 0.062 13.1 0.4 1.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 AIF82149.1 - 0.054 13.0 1.2 0.062 12.8 0.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 AIF82149.1 - 0.056 13.1 3.0 0.077 12.7 2.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Nudix_N_2 PF14803.1 AIF82149.1 - 0.07 12.8 4.9 4.8 6.9 3.3 2.2 1 1 0 1 1 1 0 Nudix N-terminal zf-C4H2 PF10146.4 AIF82149.1 - 0.09 12.7 1.4 0.094 12.7 1.0 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2256 PF10013.4 AIF82149.1 - 0.14 11.9 5.0 1.7 8.4 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) RRN7 PF11781.3 AIF82149.1 - 0.15 11.6 3.0 0.42 10.1 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 OrfB_Zn_ribbon PF07282.6 AIF82149.1 - 0.19 11.3 3.0 0.39 10.3 2.0 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_3 PF14369.1 AIF82149.1 - 0.19 11.7 2.6 4.2 7.4 1.8 2.0 1 1 0 1 1 1 0 zinc-finger zf-NADH-PPase PF09297.6 AIF82149.1 - 0.21 11.1 2.1 5.5 6.6 1.5 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Lar_restr_allev PF14354.1 AIF82149.1 - 0.3 11.4 5.1 23 5.3 3.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-C3HC4_2 PF13923.1 AIF82149.1 - 0.35 10.9 2.4 0.44 10.6 1.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 AIF82149.1 - 0.42 10.5 6.6 4 7.4 0.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF2116 PF09889.4 AIF82149.1 - 0.49 10.2 2.7 0.34 10.7 1.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_S27 PF01599.14 AIF82149.1 - 0.52 10.1 5.6 1.8 8.4 2.8 2.1 1 1 1 2 2 2 0 Ribosomal protein S27a zf-HIT PF04438.11 AIF82149.1 - 0.6 9.7 3.1 0.85 9.3 2.1 1.3 1 0 0 1 1 1 0 HIT zinc finger zf-dskA_traR PF01258.12 AIF82149.1 - 0.74 9.6 5.9 4.8 7.0 0.4 2.1 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-IS66 PF13005.2 AIF82149.1 - 2.8 7.9 6.1 12 5.9 0.1 2.1 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF2387 PF09526.5 AIF82149.1 - 2.8 7.9 5.9 1 9.3 0.2 2.0 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-C4_Topoisom PF01396.14 AIF82149.1 - 3.2 7.3 6.9 5.8 6.5 1.2 2.2 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-tcix PF14952.1 AIF82149.1 - 4.4 6.7 6.8 12 5.2 0.2 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Ogr_Delta PF04606.7 AIF82149.1 - 6.3 6.5 5.8 9.6 5.9 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger PAC2 PF09754.4 AIF82150.1 - 5e-33 114.8 0.0 5.7e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 PAC2 family TP_methylase PF00590.15 AIF82151.1 - 2.1e-31 109.2 0.0 2.4e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases AsnC_trans_reg PF01037.16 AIF82152.1 - 1.7e-11 43.6 0.2 1.7e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AIF82152.1 - 0.0071 16.0 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 GYD domain bPH_3 PF14470.1 AIF82153.1 - 0.00032 20.9 0.0 0.019 15.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial PH domain Fer4 PF00037.22 AIF82154.1 - 5.3e-11 41.6 10.4 4.1e-07 29.3 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AIF82154.1 - 1e-09 38.6 4.3 1.3e-09 38.2 3.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF82154.1 - 3.4e-08 33.1 3.0 6.4e-08 32.2 2.1 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIF82154.1 - 6.2e-08 32.1 9.6 3.6e-05 23.4 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 AIF82154.1 - 2.8e-07 30.0 8.4 0.0031 17.3 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 AIF82154.1 - 4e-06 26.5 5.6 7.9e-06 25.6 3.9 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIF82154.1 - 8.5e-06 25.9 6.4 2.9e-05 24.2 4.6 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 AIF82154.1 - 4e-05 23.8 5.3 0.07 13.5 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_4 PF12800.2 AIF82154.1 - 8.4e-05 22.6 8.8 0.031 14.6 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 AIF82154.1 - 0.00011 22.8 1.6 0.24 12.1 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 AIF82154.1 - 0.00013 21.9 4.1 0.00038 20.4 2.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 AIF82154.1 - 0.00015 22.2 9.9 0.0058 17.1 0.8 2.7 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 AIF82154.1 - 0.00053 20.3 14.0 0.073 13.6 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AIF82154.1 - 0.0016 18.7 6.3 0.034 14.4 4.4 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AIF82154.1 - 0.0025 18.2 6.5 0.18 12.2 1.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain AFP PF02420.10 AIF82154.1 - 0.13 12.4 0.4 0.13 12.4 0.3 2.4 3 0 0 3 3 2 0 Insect antifreeze protein repeat DUF1743 PF08489.6 AIF82155.1 - 2.2e-33 114.5 0.0 3.3e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1743) OrfB_Zn_ribbon PF07282.6 AIF82155.1 - 0.019 14.5 0.9 0.057 13.0 0.6 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_1 PF00130.17 AIF82155.1 - 0.12 12.0 2.1 0.4 10.4 1.4 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1610 PF07754.6 AIF82155.1 - 4.9 7.3 7.7 0.49 10.5 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Ripply PF14998.1 AIF82158.1 - 0.16 12.0 1.4 0.18 11.9 1.0 1.1 1 0 0 1 1 1 0 Transcription Regulator DUF4207 PF13904.1 AIF82158.1 - 0.18 11.1 6.1 0.19 11.0 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PRA-CH PF01502.13 AIF82159.1 - 5.9e-34 115.5 0.1 7.2e-34 115.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PALP PF00291.20 AIF82160.1 - 5.7e-64 216.2 0.7 6.7e-64 216.0 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NinF PF05810.7 AIF82160.1 - 0.0089 15.8 0.2 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 NinF protein Fungal_lectin PF07938.7 AIF82160.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal fucose-specific lectin zinc_ribbon_2 PF13240.1 AIF82160.1 - 1.1 8.7 6.2 1.9 8.0 4.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain ThiF PF00899.16 AIF82161.1 - 2.4e-48 163.4 0.6 3.9e-48 162.7 0.4 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AIF82161.1 - 2.3e-17 62.3 0.1 4.6e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain ThiS PF02597.15 AIF82161.1 - 1.4e-09 38.2 0.0 4.5e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 ThiS family Shikimate_DH PF01488.15 AIF82161.1 - 8.7e-07 29.1 0.1 1.9e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AIF82161.1 - 0.00049 19.1 0.2 0.00083 18.4 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TBP PF00352.16 AIF82161.1 - 0.0039 16.5 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Transcription factor TFIID (or TATA-binding protein, TBP) NAD_binding_7 PF13241.1 AIF82161.1 - 0.0065 16.7 0.2 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 AIF82161.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fumerase_C PF05683.7 AIF82161.1 - 0.053 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus Na_trans_assoc PF06512.8 AIF82162.1 - 0.0019 18.2 7.6 0.0028 17.6 5.3 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated Macoilin PF09726.4 AIF82162.1 - 1.1 7.4 13.4 1.4 7.1 9.3 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 AIF82162.1 - 3.8 5.4 14.0 4.8 5.1 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SDA1 PF05285.7 AIF82162.1 - 5.8 6.0 13.2 7.2 5.7 9.1 1.1 1 0 0 1 1 1 0 SDA1 CAF-1_p150 PF11600.3 AIF82162.1 - 6.9 5.9 9.8 11 5.3 6.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PolC_DP2 PF03833.8 AIF82163.1 - 1.1e-268 893.6 4.5 2.8e-268 892.2 0.3 2.5 2 1 0 2 2 2 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 AIF82163.1 - 0.3 10.9 14.6 0.76 9.6 0.1 3.3 2 1 1 3 3 3 0 zinc-ribbons DUF1272 PF06906.6 AIF82163.1 - 6.2 6.7 14.2 0.38 10.6 1.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) PcrB PF01884.12 AIF82164.1 - 5.3e-67 225.4 0.9 6.6e-67 225.1 0.6 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.16 AIF82164.1 - 6.4e-08 32.1 0.2 6.1e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.20 AIF82164.1 - 1.5e-06 27.3 0.5 1.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 AIF82164.1 - 7.5e-06 24.6 0.5 2.9e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 Tryptophan synthase alpha chain NanE PF04131.9 AIF82164.1 - 0.00075 18.5 1.7 0.0037 16.2 0.1 2.3 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Glyco_tran_WecB PF03808.8 AIF82164.1 - 0.00078 18.8 0.2 0.076 12.4 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Ribul_P_3_epim PF00834.14 AIF82164.1 - 0.0012 17.9 0.2 0.0025 16.9 0.2 1.4 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 AIF82164.1 - 0.0013 17.8 2.1 0.047 12.7 0.2 2.1 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 AIF82164.1 - 0.0023 17.0 0.2 0.037 13.0 0.0 2.1 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.13 AIF82164.1 - 0.0077 15.1 0.1 0.042 12.6 0.1 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase B12-binding PF02310.14 AIF82164.1 - 0.0078 16.0 2.4 0.88 9.4 0.1 3.4 3 1 0 3 3 3 1 B12 binding domain TMP-TENI PF02581.12 AIF82164.1 - 0.0082 15.2 0.1 0.041 13.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 AIF82164.1 - 0.013 14.4 2.5 0.017 14.1 0.4 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.10 AIF82164.1 - 0.016 14.3 1.5 3.1 6.8 0.3 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase OMPdecase PF00215.19 AIF82164.1 - 0.058 12.7 0.2 0.15 11.3 0.1 1.8 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Amidohydro_2 PF04909.9 AIF82164.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 Amidohydrolase DUF362 PF04015.7 AIF82164.1 - 0.092 12.2 0.2 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF362) HTH_27 PF13463.1 AIF82166.1 - 0.00012 22.3 0.0 0.00038 20.7 0.0 1.9 1 1 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 AIF82166.1 - 0.00014 21.5 0.1 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AIF82166.1 - 0.0093 15.7 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4058 PF13267.1 AIF82166.1 - 0.025 13.7 2.4 0.035 13.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) HxlR PF01638.12 AIF82166.1 - 0.04 13.5 0.2 0.098 12.2 0.1 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_24 PF13412.1 AIF82166.1 - 0.045 13.1 0.0 0.099 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 AIF82166.1 - 0.068 12.8 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Penicillinase_R PF03965.11 AIF82167.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Penicillinase repressor Cdc6_C PF09079.6 AIF82168.1 - 6.7e-22 77.0 0.1 2.6e-21 75.1 0.1 2.0 1 0 0 1 1 1 1 CDC6, C terminal AAA_16 PF13191.1 AIF82168.1 - 1.8e-13 50.8 1.6 1.6e-12 47.8 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AIF82168.1 - 6.7e-13 48.9 2.2 1.4e-12 47.9 0.1 2.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIF82168.1 - 2.6e-10 40.5 0.2 1.2e-09 38.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 AIF82168.1 - 1e-05 24.5 0.1 4e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AIF82168.1 - 1.5e-05 24.8 1.5 2e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 AIF82168.1 - 0.00035 20.2 2.1 0.0019 17.8 0.2 2.7 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 AIF82168.1 - 0.0011 17.8 0.1 0.0018 17.2 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 AIF82168.1 - 0.0015 17.6 0.6 0.065 12.2 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain DUF2075 PF09848.4 AIF82168.1 - 0.0032 16.4 0.7 0.0056 15.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 AIF82168.1 - 0.0033 16.9 0.0 0.0094 15.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 AIF82168.1 - 0.0043 16.7 1.5 0.0069 16.1 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 AIF82168.1 - 0.0049 16.5 0.5 0.023 14.4 0.2 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AIF82168.1 - 0.0085 15.2 0.0 0.021 13.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin KaiC PF06745.8 AIF82168.1 - 0.0096 15.0 0.3 0.032 13.3 0.2 1.8 1 1 0 1 1 1 1 KaiC AAA_11 PF13086.1 AIF82168.1 - 0.01 15.4 0.7 0.021 14.3 0.5 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIF82168.1 - 0.015 15.5 2.6 0.22 11.7 0.2 2.9 2 2 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 AIF82168.1 - 0.019 14.5 0.3 0.19 11.3 0.2 2.4 1 1 1 2 2 2 0 AAA domain ResIII PF04851.10 AIF82168.1 - 0.022 14.5 0.4 0.048 13.4 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 AIF82168.1 - 0.023 15.0 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIF82168.1 - 0.024 14.5 0.3 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AIF82168.1 - 0.028 14.9 0.5 0.063 13.7 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein TrwB_AAD_bind PF10412.4 AIF82168.1 - 0.044 12.4 0.1 1.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 AIF82168.1 - 0.045 13.2 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family RuvB_N PF05496.7 AIF82168.1 - 0.056 12.4 1.8 4.3 6.3 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 AIF82168.1 - 0.078 12.6 5.4 0.042 13.5 1.2 2.3 2 1 0 2 2 2 0 NTPase AAA_10 PF12846.2 AIF82168.1 - 0.18 11.2 2.3 3.1 7.1 0.0 3.0 2 1 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 AIF82168.1 - 0.54 9.6 3.5 2.9 7.2 0.9 2.8 2 1 0 2 2 2 0 AAA domain DNA_pol_E_B PF04042.11 AIF82169.1 - 4.4e-21 75.1 0.0 1.2e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 AIF82169.1 - 1.3e-10 41.3 0.0 2.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AIF82169.1 - 9.2e-07 28.4 0.2 2.6e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA_anti-codon PF01336.20 AIF82169.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2415 PF10313.4 AIF82169.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) HTH_24 PF13412.1 AIF82171.1 - 7.5e-05 22.0 1.8 0.00012 21.4 0.5 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF82171.1 - 0.00044 19.7 0.3 0.00087 18.7 0.2 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AIF82171.1 - 0.0018 17.9 0.2 0.005 16.4 0.1 1.8 1 0 0 1 1 1 1 HTH domain Mga PF05043.8 AIF82171.1 - 0.03 14.5 0.1 0.095 12.9 0.1 1.9 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_23 PF13384.1 AIF82171.1 - 0.042 13.4 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.11 AIF82171.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF1118 PF06549.7 AIF82171.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) HTH_28 PF13518.1 AIF82171.1 - 0.14 12.1 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DNA_RNApol_7kD PF03604.8 AIF82172.1 - 0.0017 17.8 0.6 0.16 11.4 0.1 2.1 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 AIF82172.1 - 0.0025 17.5 0.7 0.0029 17.3 0.5 1.1 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.17 AIF82172.1 - 0.0034 17.0 1.9 0.0046 16.6 1.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 AIF82172.1 - 0.02 14.5 0.3 0.021 14.4 0.2 1.0 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 AIF82172.1 - 0.05 13.0 3.7 0.071 12.6 2.6 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 AIF82172.1 - 0.07 12.9 0.6 0.084 12.6 0.4 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-C2H2_6 PF13912.1 AIF82172.1 - 0.28 11.1 4.0 3.6 7.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Mu-like_Com PF10122.4 AIF82172.1 - 0.31 10.1 2.5 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com XPA_N PF01286.13 AIF82172.1 - 0.49 10.1 3.2 0.83 9.3 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal COX15-CtaA PF02628.10 AIF82173.1 - 3.1e-18 65.7 9.6 4.4e-18 65.1 6.7 1.3 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein E1-E2_ATPase PF00122.15 AIF82173.1 - 0.23 10.4 2.6 0.65 8.9 1.8 1.8 1 1 0 1 1 1 0 E1-E2 ATPase Response_reg PF00072.19 AIF82174.1 - 6.1e-13 48.7 0.0 6.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Guanylate_cyc PF00211.15 AIF82176.1 - 1.2e-16 60.6 0.0 2.9e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HTH_23 PF13384.1 AIF82176.1 - 0.0029 17.1 0.0 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 AIF82176.1 - 0.0076 16.3 0.0 0.02 15.0 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn helix PAX PF00292.13 AIF82176.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 'Paired box' domain TFIIE_alpha PF02002.12 AIF82179.1 - 4.3e-21 74.3 3.4 5.2e-21 74.1 0.7 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit Y1_Tnp PF01797.11 AIF82179.1 - 0.055 13.3 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Transposase IS200 like HTH_9 PF08221.6 AIF82179.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2201_N PF13203.1 AIF82179.1 - 0.69 9.0 6.7 0.87 8.6 4.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2890 PF11081.3 AIF82179.1 - 0.97 9.4 11.7 2.2 8.2 8.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pox_A12 PF04651.8 AIF82179.1 - 3.5 7.7 9.1 5.5 7.0 6.3 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein Peptidase_S30 PF01577.11 AIF82179.1 - 7.9 5.7 13.6 19 4.5 0.1 2.1 1 1 1 2 2 2 0 Potyvirus P1 protease HTH_19 PF12844.2 AIF82180.1 - 5.2e-10 39.2 0.0 8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 AIF82180.1 - 2.5e-08 33.6 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 AIF82180.1 - 4.1e-08 33.2 0.0 7.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 AIF82180.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.1 AIF82180.1 - 0.072 12.8 0.0 5.4 6.8 0.0 2.4 1 1 1 2 2 2 0 MerR HTH family regulatory protein DUF3606 PF12244.3 AIF82180.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Tautomerase PF01361.16 AIF82181.1 - 2.6e-13 49.3 0.0 2.8e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 AIF82181.1 - 5.9e-09 35.8 0.0 6.3e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.1 AIF82181.1 - 0.019 14.9 0.0 0.019 14.9 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme Ketoacyl-synt_2 PF13723.1 AIF82181.1 - 0.095 11.9 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CN_hydrolase PF00795.17 AIF82182.1 - 1.9e-29 102.3 0.0 2.6e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ank_4 PF13637.1 AIF82182.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) bPH_3 PF14470.1 AIF82183.1 - 2.6e-15 56.4 0.0 3.5e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Bacterial PH domain SHOCT PF09851.4 AIF82183.1 - 1.2e-08 34.1 1.9 1.2e-08 34.1 1.3 2.3 2 0 0 2 2 2 1 Short C-terminal domain bPH_2 PF03703.9 AIF82183.1 - 0.038 14.0 0.8 0.12 12.3 0.5 1.9 1 1 0 1 1 1 0 Bacterial PH domain Peripla_BP_1 PF00532.16 AIF82183.1 - 0.053 12.7 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Alpha-2-MRAP_C PF06401.6 AIF82183.1 - 0.066 13.0 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain tRNA-synt_1f PF01921.13 AIF82184.1 - 0.033 12.8 0.0 0.033 12.8 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) FYVE PF01363.16 AIF82184.1 - 0.12 12.2 5.7 0.14 12.0 4.0 1.1 1 0 0 1 1 1 0 FYVE zinc finger Topoisom_bac PF01131.15 AIF82185.1 - 4.5e-107 358.3 0.0 5.3e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 AIF82185.1 - 4.5e-12 45.8 0.0 1.2e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.14 AIF82185.1 - 0.00022 20.6 0.9 0.00051 19.4 0.6 1.7 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger DUF2367 PF10164.4 AIF82185.1 - 0.003 17.3 0.1 0.0064 16.3 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF3797 PF12677.2 AIF82185.1 - 0.74 9.4 2.7 8.5 6.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Thiolase_C PF02803.13 AIF82186.1 - 2.5e-13 49.5 0.9 1.4e-09 37.3 0.0 3.4 2 2 1 3 3 3 2 Thiolase, C-terminal domain Thiolase_N PF00108.18 AIF82186.1 - 1.1e-08 34.4 0.9 5.5e-08 32.1 0.4 2.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 AIF82186.1 - 5.8e-05 22.6 1.3 0.025 14.0 0.4 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AIF82186.1 - 0.0041 16.9 0.6 0.22 11.3 0.0 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 AIF82186.1 - 0.04 13.5 0.2 7.6 6.2 0.1 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF35 PF01796.12 AIF82187.1 - 4.3e-07 30.0 0.1 5.7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain zinc_ribbon_2 PF13240.1 AIF82187.1 - 0.00041 19.7 0.4 0.00074 18.9 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain FYVE PF01363.16 AIF82187.1 - 0.0044 16.8 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.2 AIF82187.1 - 0.018 14.8 0.4 0.027 14.2 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 AIF82187.1 - 0.063 13.0 1.2 0.09 12.5 0.9 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2082 PF09855.4 AIF82187.1 - 0.086 12.6 1.6 7.2 6.5 0.1 2.4 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) MTHFR_C PF12225.3 AIF82187.1 - 0.089 12.3 0.8 0.14 11.7 0.5 1.2 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal zf-ribbon_3 PF13248.1 AIF82187.1 - 0.21 10.8 1.4 0.53 9.5 1.0 1.7 1 1 1 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AIF82187.1 - 0.51 9.8 4.0 1.5 8.4 2.8 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain CENP-F_leu_zip PF10473.4 AIF82188.1 - 0.0023 17.7 6.0 0.032 14.1 1.3 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 AIF82188.1 - 0.0073 14.7 2.6 0.0089 14.4 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) HalX PF08663.5 AIF82188.1 - 0.1 12.5 0.3 0.1 12.5 0.2 2.1 2 0 0 2 2 2 0 HalX domain CbiK PF06180.6 AIF82188.1 - 0.11 11.5 0.5 0.14 11.2 0.3 1.0 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) XkdW PF09636.5 AIF82188.1 - 0.18 11.6 2.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 XkdW protein Seryl_tRNA_N PF02403.17 AIF82188.1 - 0.44 10.5 6.8 1.1 9.2 4.7 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2951 PF11166.3 AIF82188.1 - 1.5 8.7 5.0 1.9 8.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF4355 PF14265.1 AIF82188.1 - 2.2 8.2 8.0 6.6 6.6 5.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) DUF733 PF05306.6 AIF82188.1 - 2.4 8.4 5.8 38 4.6 4.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF733) TF_Zn_Ribbon PF08271.7 AIF82189.1 - 3.2e-05 23.1 0.4 0.018 14.3 0.1 2.1 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 AIF82189.1 - 0.0008 18.5 2.4 0.093 11.9 0.2 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.6 AIF82189.1 - 0.00094 18.6 1.2 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.2 AIF82189.1 - 0.0025 17.5 0.5 0.0064 16.2 0.4 1.6 1 1 0 1 1 1 1 Double zinc ribbon Rad50_zn_hook PF04423.9 AIF82189.1 - 0.0032 16.9 0.1 0.0052 16.2 0.1 1.5 1 1 0 1 1 1 1 Rad50 zinc hook motif Prok-RING_1 PF14446.1 AIF82189.1 - 0.0038 16.9 0.6 0.44 10.3 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 AIF82189.1 - 0.0046 16.4 0.4 0.57 9.7 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zf-4CXXC_R1 PF10497.4 AIF82189.1 - 0.018 15.1 0.2 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Rtf2 PF04641.7 AIF82189.1 - 0.021 14.0 0.2 0.023 13.9 0.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Sec23_Sec24 PF04810.10 AIF82189.1 - 0.025 14.1 1.9 0.35 10.4 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_3 PF13920.1 AIF82189.1 - 0.026 14.1 1.4 0.05 13.2 0.9 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRN7 PF11781.3 AIF82189.1 - 0.031 13.7 0.5 3.8 7.0 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Rubredoxin PF00301.15 AIF82189.1 - 0.039 13.8 0.2 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin GFA PF04828.9 AIF82189.1 - 0.054 13.4 0.8 4.9 7.1 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 AIF82189.1 - 0.065 13.2 1.6 0.55 10.2 1.1 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.1 AIF82189.1 - 0.08 12.9 0.2 5.9 6.9 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CHY PF05495.7 AIF82189.1 - 0.08 13.1 0.3 0.096 12.8 0.2 1.1 1 0 0 1 1 1 0 CHY zinc finger zf-TFIIB PF13453.1 AIF82189.1 - 0.092 11.9 0.5 0.5 9.5 0.1 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger Nudix_N_2 PF14803.1 AIF82189.1 - 0.096 12.3 4.6 1.7 8.4 0.6 2.2 2 0 0 2 2 2 0 Nudix N-terminal ADK_lid PF05191.9 AIF82189.1 - 0.097 12.3 0.7 5.5 6.7 0.1 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF35_N PF12172.3 AIF82189.1 - 0.1 12.5 0.6 9.5 6.2 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-IS66 PF13005.2 AIF82189.1 - 0.11 12.5 0.2 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_5 PF13719.1 AIF82189.1 - 0.11 12.0 0.9 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AIF82189.1 - 0.12 11.9 0.9 2.2 7.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_S27 PF01599.14 AIF82189.1 - 0.12 12.2 0.7 3.9 7.3 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S27a Zn_Tnp_IS1595 PF12760.2 AIF82189.1 - 0.13 12.0 3.0 4 7.3 0.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIF82189.1 - 0.14 11.8 0.6 0.4 10.3 0.4 1.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.1 AIF82189.1 - 0.17 11.6 0.8 12 5.6 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 AIF82189.1 - 0.19 12.0 3.2 6.1 7.2 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar DNA_ligase_ZBD PF03119.11 AIF82189.1 - 0.2 11.3 0.2 0.2 11.3 0.2 2.1 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_ribbon_recom PF13408.1 AIF82189.1 - 0.28 11.4 3.5 5.3 7.3 0.7 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF164 PF02591.10 AIF82189.1 - 0.33 10.8 1.6 1.9 8.3 1.4 1.8 1 1 1 2 2 2 0 Putative zinc ribbon domain Snf7 PF03357.16 AIF82190.1 - 3.2e-06 26.6 3.2 8.6e-06 25.2 2.2 1.8 1 1 0 1 1 1 1 Snf7 DASH_Dad2 PF08654.5 AIF82190.1 - 3.5 7.6 6.7 0.62 10.0 0.1 2.8 2 1 0 3 3 3 0 DASH complex subunit Dad2 NRDD PF13597.1 AIF82191.1 - 4.7e-18 64.5 0.2 4.2e-17 61.4 0.1 2.1 2 0 0 2 2 2 1 Anaerobic ribonucleoside-triphosphate reductase ATP-cone PF03477.11 AIF82191.1 - 1.5e-09 38.1 0.2 4.8e-09 36.5 0.2 1.9 1 0 0 1 1 1 1 ATP cone domain HTH_20 PF12840.2 AIF82191.1 - 3.3e-09 36.4 0.2 1.3e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain zf-C3HC4_3 PF13920.1 AIF82191.1 - 0.12 12.0 0.5 0.22 11.2 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribonuc_red_lgC PF02867.10 AIF82192.1 - 1.2e-156 522.4 0.0 2.7e-156 521.2 0.0 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AIF82192.1 - 4.4e-31 106.5 0.2 1.8e-30 104.5 0.1 2.1 1 1 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AIF82192.1 - 4.7e-19 68.6 0.4 1.7e-18 66.8 0.3 2.1 1 0 0 1 1 1 1 ATP cone domain RecX PF02631.11 AIF82192.1 - 0.017 15.3 0.1 0.41 10.8 0.0 2.8 2 0 0 2 2 2 0 RecX family zf-ribbon_3 PF13248.1 AIF82192.1 - 0.35 10.1 2.7 0.66 9.2 1.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain adh_short PF00106.20 AIF82193.1 - 8.7e-20 71.2 1.0 8.7e-20 71.2 0.7 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AIF82193.1 - 1.9e-09 37.4 0.5 3.2e-09 36.7 0.4 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AIF82193.1 - 6.4e-07 29.3 0.3 1.3e-06 28.4 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AIF82193.1 - 0.00035 20.0 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AIF82193.1 - 0.00071 19.6 0.7 0.0023 17.9 0.5 1.9 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AIF82193.1 - 0.016 14.0 0.1 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 AIF82193.1 - 0.036 13.7 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1800 PF08811.6 AIF82193.1 - 0.062 12.2 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Eno-Rase_NADH_b PF12242.3 AIF82193.1 - 0.5 10.1 3.9 0.8 9.5 0.5 2.5 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Prion_bPrPp PF11587.3 AIF82195.1 - 0.13 11.9 1.8 0.35 10.5 1.2 1.8 1 1 0 1 1 1 0 Major prion protein bPrPp - N terminal AP_endonuc_2 PF01261.19 AIF82197.1 - 0.00096 18.4 0.0 0.0033 16.7 0.0 2.0 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel Methyltrans_RNA PF04452.9 AIF82197.1 - 0.03 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase NAD_synthase PF02540.12 AIF82198.1 - 2.4e-78 262.3 0.0 2.8e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 AIF82198.1 - 2.9e-06 26.1 0.0 8.5e-05 21.2 0.0 2.3 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 AIF82198.1 - 4.2e-05 23.1 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AIF82198.1 - 0.0017 17.7 0.0 0.0034 16.6 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Rieske PF00355.21 AIF82200.1 - 1.2e-15 56.7 0.1 1.4e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AIF82200.1 - 0.0001 21.9 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ferritin PF00210.19 AIF82201.1 - 6.6e-19 68.0 0.0 8.4e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AIF82201.1 - 0.024 14.9 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Rubrerythrin HTH_45 PF14947.1 AIF82202.1 - 3.3e-16 58.8 0.0 4.3e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix Peptidase_M48 PF01435.13 AIF82203.1 - 2e-36 125.6 0.2 6.1e-36 124.0 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 AIF82203.1 - 4.2e-09 35.7 0.4 5.2e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 Peptidase_MA_2 PF13485.1 AIF82203.1 - 0.019 15.0 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily HemY_N PF07219.8 AIF82203.1 - 2 7.9 6.8 0.14 11.6 0.2 2.2 2 0 0 2 2 2 0 HemY protein N-terminus DUF2976 PF11190.3 AIF82204.1 - 0.17 11.4 2.8 0.2 11.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Cation_efflux PF01545.16 AIF82204.1 - 0.3 10.1 2.0 0.31 10.0 1.4 1.0 1 0 0 1 1 1 0 Cation efflux family DUF1469 PF07332.6 AIF82204.1 - 0.83 9.3 4.6 1 9.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF3185 PF11381.3 AIF82204.1 - 2.8 7.7 10.6 0.57 9.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3040 PF11239.3 AIF82204.1 - 4.4 7.4 8.8 2.1 8.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Tetraspannin PF00335.15 AIF82204.1 - 5.4 6.2 8.4 31 3.7 5.8 1.8 1 1 0 1 1 1 0 Tetraspanin family YiaAB PF05360.9 AIF82204.1 - 5.5 6.6 10.0 0.46 10.0 0.8 2.1 2 0 0 2 2 2 0 yiaA/B two helix domain IncA PF04156.9 AIF82204.1 - 7.6 6.0 7.3 0.5 9.9 0.6 1.8 1 1 1 2 2 2 0 IncA protein DUF368 PF04018.8 AIF82206.1 - 0.19 10.9 3.6 0.22 10.6 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Tetraspannin PF00335.15 AIF82206.1 - 0.99 8.6 3.8 2 7.5 2.6 1.5 1 0 0 1 1 1 0 Tetraspanin family MS_channel PF00924.13 AIF82207.1 - 6.3e-15 55.0 7.8 2.4e-14 53.1 4.6 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel Glyco_hydro_43 PF04616.9 AIF82207.1 - 0.045 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 DUF420 PF04238.7 AIF82207.1 - 1.1 9.2 10.0 3.7 7.5 6.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF420) GtrA PF04138.9 AIF82207.1 - 4.1 7.3 10.2 1.7 8.6 1.4 2.3 1 1 1 2 2 2 0 GtrA-like protein DUF21 PF01595.15 AIF82207.1 - 4.9 6.3 13.7 0.58 9.4 5.5 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF21 DUF3552 PF12072.3 AIF82208.1 - 0.13 11.4 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Oxidored_q1_N PF00662.15 AIF82209.1 - 0.24 10.9 3.2 0.37 10.3 2.2 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus ECR1_N PF14382.1 AIF82210.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Muted PF14942.1 AIF82211.1 - 0.03 14.1 0.2 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Enkurin PF13864.1 AIF82211.1 - 0.03 14.5 2.8 1.5 9.1 0.3 2.5 2 1 0 2 2 2 0 Calmodulin-binding ERp29 PF07749.7 AIF82211.1 - 0.051 14.2 0.3 0.14 12.7 0.0 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF1743 PF08489.6 AIF82211.1 - 0.074 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) Imm3 PF14425.1 AIF82211.1 - 0.14 12.1 0.9 0.23 11.4 0.2 1.7 1 1 1 2 2 2 0 Immunity protein Imm3 7tm_2 PF00002.19 AIF82211.1 - 0.14 11.1 0.2 0.22 10.5 0.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Cupredoxin_1 PF13473.1 AIF82212.1 - 0.0008 19.2 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Cupredoxin-like domain Cu-oxidase_3 PF07732.10 AIF82212.1 - 0.003 17.2 0.0 0.57 9.9 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Copper-bind PF00127.15 AIF82212.1 - 0.0037 17.4 0.0 0.0085 16.2 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Inhibitor_I9 PF05922.11 AIF82213.1 - 0.04 14.4 0.1 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase inhibitor I9 Cupredoxin_1 PF13473.1 AIF82214.1 - 4.1e-10 39.4 0.3 1.1e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 Cupredoxin-like domain Copper-bind PF00127.15 AIF82214.1 - 3.5e-08 33.5 0.1 3.5e-08 33.5 0.1 2.6 1 1 1 2 2 2 1 Copper binding proteins, plastocyanin/azurin family DAP PF15228.1 AIF82214.1 - 0.011 16.4 0.5 0.033 14.9 0.3 1.9 1 0 0 1 1 1 0 Death-associated protein EcoRII-C PF09019.6 AIF82217.1 - 0.0024 17.7 0.1 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 EcoRII C terminal Ferritin_2 PF13668.1 AIF82217.1 - 0.06 13.2 0.1 0.076 12.9 0.0 1.3 1 1 0 1 1 1 0 Ferritin-like domain DUF4456 PF14644.1 AIF82217.1 - 0.064 12.4 0.1 0.077 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4456) DUF3490 PF11995.3 AIF82217.1 - 0.09 12.3 0.6 0.089 12.3 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) PAC2 PF09754.4 AIF82218.1 - 1.9e-31 109.6 0.0 1.1e-30 107.1 0.0 1.8 1 1 0 1 1 1 1 PAC2 family Isochorismatase PF00857.15 AIF82219.1 - 4.9e-37 127.5 0.0 5.9e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family NYN PF01936.13 AIF82219.1 - 0.068 13.4 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 NYN domain Glycos_transf_2 PF00535.21 AIF82220.1 - 2.6e-12 46.7 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 NTP_transf_3 PF12804.2 AIF82220.1 - 0.00019 21.5 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_3 PF13641.1 AIF82220.1 - 0.0049 16.7 0.0 0.0069 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AIF82220.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF960 PF06124.6 AIF82220.1 - 0.099 12.9 0.3 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) ATP-synt_F PF01990.12 AIF82220.1 - 0.12 12.7 0.1 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit YwpF PF14183.1 AIF82220.1 - 0.13 11.9 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 YwpF-like protein Glycos_transf_1 PF00534.15 AIF82221.1 - 2.7e-24 85.5 0.1 4.8e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AIF82221.1 - 1.1e-10 41.7 0.0 2.9e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AIF82221.1 - 3e-05 23.8 0.2 0.0015 18.2 0.1 2.4 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Exostosin PF03016.10 AIF82221.1 - 0.047 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Exostosin family CGI-121 PF08617.5 AIF82221.1 - 0.051 13.2 0.3 0.12 12.0 0.1 1.6 1 1 0 1 1 1 0 Kinase binding protein CGI-121 SBF PF01758.11 AIF82222.1 - 4.5e-14 52.2 14.0 4.5e-14 52.2 9.7 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4137 PF13593.1 AIF82222.1 - 7.3e-08 31.8 21.5 1.2e-07 31.1 14.9 1.3 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) LSR PF05624.9 AIF82223.1 - 0.026 14.2 4.5 0.036 13.8 3.1 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) SAE2 PF08573.5 AIF82223.1 - 2.3 8.9 4.8 3 8.5 3.4 1.2 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Abhydrolase_5 PF12695.2 AIF82224.1 - 2.8e-17 62.8 0.0 3.9e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIF82224.1 - 1.4e-09 38.1 0.4 0.00042 20.2 0.3 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIF82224.1 - 7.1e-08 31.9 0.1 0.00078 18.7 0.0 2.6 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 AIF82224.1 - 1.6e-07 30.8 0.0 2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 AIF82224.1 - 3.6e-05 23.3 0.1 0.21 10.9 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 AIF82224.1 - 0.00096 18.9 0.0 0.87 9.2 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 AIF82224.1 - 0.067 12.7 0.1 0.32 10.5 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AIF82224.1 - 0.091 12.1 0.0 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Erythro_esteras PF05139.9 AIF82225.1 - 5.1e-105 351.4 8.2 8.7e-95 317.8 6.3 2.4 1 1 0 2 2 2 2 Erythromycin esterase DUF399 PF04187.8 AIF82225.1 - 0.023 14.1 0.3 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF399 DUF2795 PF11387.3 AIF82226.1 - 2e-09 37.1 0.1 5.2e-09 35.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2795) DUF3105 PF11303.3 AIF82226.1 - 0.031 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) DUF2795 PF11387.3 AIF82227.1 - 4.4e-17 61.6 1.1 1.8e-08 34.0 0.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2795) zf-C2H2_4 PF13894.1 AIF82227.1 - 0.00075 19.6 0.8 0.0015 18.7 0.1 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF82227.1 - 0.00083 19.5 0.2 0.0019 18.4 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type Thr_synth_N PF14821.1 AIF82227.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Threonine synthase N terminus DUF3449 PF11931.3 AIF82227.1 - 0.13 11.7 0.9 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) HicB PF05534.7 AIF82229.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 HicB family RHH_1 PF01402.16 AIF82229.1 - 0.0065 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family Arc PF03869.9 AIF82229.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Arc-like DNA binding domain BiPBP_C PF06832.7 AIF82230.1 - 0.035 14.0 0.1 0.17 11.8 0.1 2.2 1 1 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family PepSY PF03413.14 AIF82232.1 - 0.023 15.3 0.1 0.039 14.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF4097 PF13349.1 AIF82232.1 - 0.057 12.9 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Claudin_2 PF13903.1 AIF82232.1 - 0.061 13.0 1.3 0.098 12.3 0.9 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2562 PF10814.3 AIF82232.1 - 0.16 11.9 0.8 0.3 11.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) RskA PF10099.4 AIF82232.1 - 1.5 8.5 6.3 3.4 7.3 3.4 1.9 1 1 0 2 2 2 0 Anti-sigma-K factor rskA GRP PF07172.6 AIF82232.1 - 1.9 9.0 9.4 16 6.0 3.8 2.3 2 0 0 2 2 2 0 Glycine rich protein family Herpes_gE PF02480.11 AIF82235.1 - 0.0097 14.2 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Cation_efflux PF01545.16 AIF82235.1 - 0.013 14.6 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family RCR PF12273.3 AIF82235.1 - 0.019 15.4 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Na_H_antiport_1 PF06965.7 AIF82235.1 - 0.033 12.9 0.5 0.045 12.5 0.3 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter 1 zf-C2H2_6 PF13912.1 AIF82236.1 - 1.2e-06 28.2 0.1 1.6e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AIF82236.1 - 6.5e-05 22.9 0.1 0.0001 22.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 AIF82236.1 - 9.8e-05 22.4 0.4 0.00014 22.0 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF82236.1 - 0.0017 18.5 0.3 0.0026 17.9 0.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 AIF82236.1 - 0.0018 18.3 0.1 0.0029 17.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 AIF82236.1 - 0.0075 16.5 3.0 0.014 15.6 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger double domain ABC_tran PF00005.22 AIF82237.1 - 1.4e-29 103.1 0.0 3e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF82237.1 - 3.4e-15 56.7 0.0 1.4e-10 41.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AIF82237.1 - 4.1e-07 29.4 0.1 1.7e-05 24.0 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF4162 PF13732.1 AIF82237.1 - 7.8e-05 23.0 0.0 0.00034 21.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA PF00004.24 AIF82237.1 - 0.0082 16.3 0.2 0.038 14.1 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 AIF82237.1 - 0.018 14.2 0.1 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AIF82237.1 - 0.029 14.6 0.8 0.029 14.6 0.5 1.9 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 AIF82237.1 - 0.033 13.7 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AIF82237.1 - 0.044 13.1 0.0 9 5.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 AIF82238.1 - 3e-38 131.1 18.4 3e-38 131.1 12.7 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AIF82238.1 - 2.8e-16 59.4 24.6 4.2e-16 58.9 17.1 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 AIF82238.1 - 2.8e-12 46.1 16.0 3.5e-12 45.7 11.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 AIF82238.1 - 8.7e-08 31.6 17.1 1.2e-07 31.2 11.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3814 PF12769.2 AIF82238.1 - 0.83 9.8 12.7 3.2 7.9 1.3 4.0 1 1 1 3 3 3 0 Domain of unknown function (DUF3814) zf-C2H2 PF00096.21 AIF82239.1 - 0.0018 18.4 0.1 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AIF82239.1 - 0.006 16.6 0.2 0.012 15.7 0.2 1.6 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AIF82239.1 - 0.0067 16.6 0.0 0.0095 16.2 0.0 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIF82239.1 - 0.0082 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_3 PF13878.1 AIF82239.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO APP_E2 PF12925.2 AIF82239.1 - 0.12 11.9 0.3 0.13 11.8 0.2 1.0 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein zf-C2H2_2 PF12756.2 AIF82239.1 - 0.12 12.4 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) HATPase_c PF02518.21 AIF82242.1 - 1.2e-23 82.9 0.2 2.3e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF82242.1 - 5.5e-13 48.7 1.6 9.9e-13 47.8 0.5 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Cache_1 PF02743.13 AIF82242.1 - 0.03 13.8 0.2 0.5 9.9 0.0 2.9 3 0 0 3 3 3 0 Cache domain DUF4307 PF14155.1 AIF82242.1 - 0.13 12.0 0.7 0.83 9.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) HATPase_c_5 PF14501.1 AIF82242.1 - 0.14 11.8 2.7 0.18 11.5 0.2 2.4 2 1 0 2 2 2 0 GHKL domain GATA PF00320.22 AIF82243.1 - 0.08 12.2 0.2 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 GATA zinc finger DZR PF12773.2 AIF82243.1 - 0.91 9.3 3.4 8.7 6.2 2.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF82243.1 - 2.7 7.2 5.6 7.6 5.8 3.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Response_reg PF00072.19 AIF82244.1 - 1.8e-18 66.5 0.1 2.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain COX4_pro_2 PF07835.7 AIF82248.1 - 0.086 12.8 1.9 0.11 12.4 1.3 1.2 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2075 PF09848.4 AIF82249.1 - 0.097 11.6 0.0 0.097 11.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HTH_45 PF14947.1 AIF82251.1 - 5.6e-16 58.1 1.3 7.5e-16 57.7 0.8 1.3 1 1 0 1 1 1 1 Winged helix-turn-helix zf-PARP PF00645.13 AIF82252.1 - 0.014 15.6 2.1 0.024 14.8 1.5 1.4 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region C1_1 PF00130.17 AIF82252.1 - 0.025 14.2 0.9 0.054 13.2 0.7 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF572 PF04502.8 AIF82252.1 - 0.028 13.6 0.6 0.033 13.3 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4451 PF14616.1 AIF82252.1 - 0.051 13.3 0.4 0.052 13.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) zf-HC5HC2H_2 PF13832.1 AIF82252.1 - 0.062 13.2 0.2 0.072 13.0 0.1 1.1 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 AIF82252.1 - 0.087 12.5 1.1 0.2 11.4 0.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Med27 PF11571.3 AIF82252.1 - 0.097 12.8 0.2 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 27 LIM PF00412.17 AIF82252.1 - 0.11 12.5 0.9 0.26 11.3 0.6 1.6 1 1 0 1 1 1 0 LIM domain Response_reg PF00072.19 AIF82253.1 - 1.3e-15 57.3 0.2 3e-15 56.1 0.1 1.7 1 1 0 1 1 1 1 Response regulator receiver domain Cation_efflux PF01545.16 AIF82255.1 - 1e-45 156.0 7.7 1.2e-45 155.7 5.4 1.0 1 0 0 1 1 1 1 Cation efflux family DUF2976 PF11190.3 AIF82255.1 - 0.7 9.4 5.6 0.33 10.4 1.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) DNA_RNApol_7kD PF03604.8 AIF82256.1 - 0.067 12.6 0.2 0.089 12.2 0.1 1.2 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.13 AIF82256.1 - 0.13 11.9 0.1 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Pro-rich PF15240.1 AIF82258.1 - 0.00012 22.1 5.1 0.00016 21.7 3.5 1.2 1 0 0 1 1 1 1 Proline-rich DUF2360 PF10152.4 AIF82258.1 - 0.51 10.6 3.0 0.92 9.7 2.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mucin PF01456.12 AIF82259.1 - 0.042 13.6 3.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Oxysterol_BP PF01237.13 AIF82259.1 - 0.12 10.7 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Glyco_transf_18 PF15024.1 AIF82259.1 - 0.16 10.3 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 CHB_HEX_C PF03174.8 AIF82260.1 - 2.8e-15 55.8 5.3 2.8e-15 55.8 3.7 3.2 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 AIF82260.1 - 1.3e-13 50.5 4.7 1.3e-13 50.5 3.3 3.5 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIF82260.1 - 6.5e-13 48.5 2.5 6.5e-13 48.5 1.8 2.9 3 0 0 3 3 3 1 Fn3 associated Polysacc_deac_1 PF01522.16 AIF82260.1 - 9.4e-12 44.6 0.0 2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase HYR PF02494.11 AIF82260.1 - 1.6e-05 24.8 8.1 0.00092 19.1 1.4 3.4 2 1 0 2 2 2 2 HYR domain Big_3_4 PF13754.1 AIF82260.1 - 8.2e-05 22.8 12.2 0.0019 18.5 0.1 4.9 4 1 0 4 4 4 2 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.8 AIF82260.1 - 0.01 15.5 1.5 1 9.1 0.1 3.0 3 0 0 3 3 3 0 Y_Y_Y domain C5-epim_C PF06662.8 AIF82261.1 - 1e-18 67.3 4.9 2.5e-18 66.0 3.4 1.6 1 1 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 AIF82261.1 - 0.0029 15.9 0.8 0.029 12.6 0.5 1.9 1 1 1 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 AIF82261.1 - 0.0057 15.7 0.8 0.048 12.6 0.1 2.1 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 Tenui_NS3 PF05310.7 AIF82261.1 - 0.047 13.5 0.1 0.94 9.3 0.0 2.3 2 1 0 2 2 2 0 Tenuivirus movement protein Strep_his_triad PF04270.8 AIF82261.1 - 4.5 7.0 7.1 32 4.3 3.4 2.7 2 1 0 2 2 2 0 Streptococcal histidine triad protein AmoC PF04896.7 AIF82263.1 - 5.1e-15 55.1 4.5 6e-15 54.9 3.1 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C Polysacc_deac_1 PF01522.16 AIF82264.1 - 6.7e-07 28.9 0.0 1.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase HYR PF02494.11 AIF82264.1 - 4.5e-05 23.3 0.5 4.5e-05 23.3 0.3 2.4 3 0 0 3 3 3 1 HYR domain Big_3_3 PF13750.1 AIF82264.1 - 0.051 12.9 2.2 0.18 11.1 0.1 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Gmad2 PF10648.4 AIF82264.1 - 0.054 13.6 0.4 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Big_3_4 PF13754.1 AIF82264.1 - 0.1 12.9 11.3 1.8 8.9 0.1 3.5 2 2 1 3 3 3 0 Bacterial Ig-like domain (group 3) MFS_1 PF07690.11 AIF82265.1 - 1.9e-31 109.0 37.4 1.9e-31 109.0 25.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily IncA PF04156.9 AIF82265.1 - 0.13 11.8 0.1 0.13 11.8 0.1 3.2 4 1 0 4 4 4 0 IncA protein PTS_EIIA_2 PF00359.17 AIF82267.1 - 0.036 13.7 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF3330 PF11809.3 AIF82270.1 - 0.0044 16.8 0.4 0.0048 16.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) RecR PF02132.10 AIF82270.1 - 0.23 10.9 2.9 0.31 10.5 0.2 2.0 2 0 0 2 2 2 0 RecR protein zinc_ribbon_4 PF13717.1 AIF82270.1 - 0.57 9.9 3.0 0.87 9.3 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PHD_2 PF13831.1 AIF82270.1 - 0.82 9.0 4.1 3.3 7.0 0.3 2.1 2 0 0 2 2 2 0 PHD-finger HTH_45 PF14947.1 AIF82274.1 - 4.9e-12 45.4 0.2 5.2e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix AAA_22 PF13401.1 AIF82276.1 - 0.0052 16.9 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2325 PF10087.4 AIF82276.1 - 0.027 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Response_reg PF00072.19 AIF82277.1 - 1e-21 77.0 0.0 1.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain MEDS PF14417.1 AIF82278.1 - 5.6e-08 32.0 0.1 7.6e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain KaiC PF06745.8 AIF82278.1 - 4.9e-06 25.8 0.0 6.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 KaiC Chlor_dismutase PF06778.7 AIF82278.1 - 0.21 11.2 2.1 3.7 7.2 0.3 2.4 1 1 0 2 2 2 0 Chlorite dismutase zf-C2H2_4 PF13894.1 AIF82280.1 - 0.0011 19.1 13.4 0.0026 17.9 0.1 2.7 3 0 0 3 3 2 2 C2H2-type zinc finger Lar_restr_allev PF14354.1 AIF82280.1 - 0.0023 18.2 0.9 0.0034 17.6 0.6 1.4 1 1 0 1 1 1 1 Restriction alleviation protein Lar DUF2321 PF10083.4 AIF82280.1 - 0.0063 16.0 0.4 0.0075 15.7 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2 PF00096.21 AIF82280.1 - 0.0085 16.3 15.6 0.14 12.5 2.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type Prok-RING_1 PF14446.1 AIF82280.1 - 0.018 14.7 5.3 1.7 8.4 0.4 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_6 PF13912.1 AIF82280.1 - 0.019 14.8 3.1 1.7 8.6 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger YscO PF07321.7 AIF82280.1 - 0.029 14.1 4.1 0.035 13.9 2.9 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO DUF629 PF04780.7 AIF82280.1 - 0.058 11.9 9.2 0.087 11.3 6.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF629) LIM PF00412.17 AIF82280.1 - 0.068 13.2 3.6 0.094 12.8 2.2 1.5 1 1 0 1 1 1 0 LIM domain DZR PF12773.2 AIF82280.1 - 0.084 12.6 0.2 0.17 11.7 0.2 1.5 1 1 0 1 1 1 0 Double zinc ribbon FYDLN_acid PF09538.5 AIF82280.1 - 0.087 13.4 3.0 0.14 12.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C2H2_jaz PF12171.3 AIF82280.1 - 0.097 12.8 6.1 1.2 9.3 0.9 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ZZ PF00569.12 AIF82280.1 - 0.11 12.0 4.4 4.2 6.9 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type XPA_N PF01286.13 AIF82280.1 - 0.15 11.7 6.2 0.99 9.1 0.2 2.4 2 0 0 2 2 2 0 XPA protein N-terminal UPF0547 PF10571.4 AIF82280.1 - 0.19 11.4 2.6 0.41 10.3 1.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Elf1 PF05129.8 AIF82280.1 - 0.23 11.1 4.3 0.17 11.6 1.8 1.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_3 PF14369.1 AIF82280.1 - 0.41 10.6 0.2 0.41 10.6 0.2 2.0 2 0 0 2 2 2 0 zinc-finger DNA_RNApol_7kD PF03604.8 AIF82280.1 - 0.8 9.2 4.1 0.72 9.3 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ADK_lid PF05191.9 AIF82280.1 - 0.8 9.4 3.1 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid FYVE PF01363.16 AIF82280.1 - 1.9 8.4 6.3 1.6 8.7 2.1 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-HYPF PF07503.7 AIF82280.1 - 5.9 6.4 5.7 0.96 8.9 1.0 1.9 2 0 0 2 2 2 0 HypF finger DUF4131 PF13567.1 AIF82281.1 - 0.14 11.5 2.3 0.2 11.0 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EmrE PF13536.1 AIF82281.1 - 8.3 6.6 10.2 3.2 7.9 3.2 2.4 1 1 1 2 2 2 0 Multidrug resistance efflux transporter HATPase_c PF02518.21 AIF82283.1 - 6.6e-23 80.5 0.3 2e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF82283.1 - 1.4e-12 47.4 2.4 2.8e-12 46.4 0.5 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Cu-oxidase_3 PF07732.10 AIF82285.1 - 1.3e-23 82.9 11.4 5e-23 81.0 0.1 3.6 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AIF82285.1 - 9.1e-17 60.8 9.3 5e-06 26.0 0.0 3.8 4 0 0 4 4 4 3 Multicopper oxidase Copper-bind PF00127.15 AIF82285.1 - 2e-11 43.9 2.6 1.8e-08 34.4 0.2 3.3 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF82285.1 - 7.2e-11 41.8 0.0 9.5e-08 31.8 0.0 3.5 3 1 0 3 3 3 2 Cupredoxin-like domain Cu-oxidase PF00394.17 AIF82285.1 - 6.1e-05 22.9 0.3 0.037 13.9 0.0 3.5 3 0 0 3 3 3 1 Multicopper oxidase PKD PF00801.15 AIF82285.1 - 0.01 15.5 0.5 0.045 13.5 0.3 2.1 1 0 0 1 1 1 0 PKD domain RNR_N PF08343.5 AIF82287.1 - 6.8e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase N-terminal HicB PF05534.7 AIF82287.1 - 0.00013 21.4 0.0 0.0006 19.3 0.0 2.0 2 0 0 2 2 2 1 HicB family Arc PF03869.9 AIF82287.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Arc-like DNA binding domain DUF4619 PF15398.1 AIF82289.1 - 0.022 14.1 0.4 0.022 14.1 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Response_reg PF00072.19 AIF82293.1 - 0.0019 18.2 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Polysacc_deac_1 PF01522.16 AIF82295.1 - 4.2e-12 45.7 0.0 7.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Big_3_4 PF13754.1 AIF82295.1 - 7.4e-06 26.1 24.3 0.00012 22.3 4.1 3.6 2 1 1 3 3 3 2 Bacterial Ig-like domain (group 3) HYR PF02494.11 AIF82295.1 - 2e-05 24.5 5.0 2.1e-05 24.4 1.3 2.4 2 0 0 2 2 2 1 HYR domain PepSY PF03413.14 AIF82297.1 - 2.2e-12 47.4 0.5 5.1e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain Lipid_bd PF12888.2 AIF82297.1 - 0.69 9.7 7.2 0.74 9.6 0.2 3.1 1 1 1 3 3 3 0 Lipid-binding putative hydrolase Arc_trans_TRASH PF08394.5 AIF82298.1 - 0.0083 16.2 1.4 0.015 15.4 0.9 1.5 1 0 0 1 1 1 1 Archaeal TRASH domain FLYWCH PF04500.11 AIF82298.1 - 0.099 12.5 1.1 0.15 12.0 0.7 1.3 1 0 0 1 1 1 0 FLYWCH zinc finger domain Zn_ribbon_recom PF13408.1 AIF82298.1 - 0.21 11.8 2.6 0.34 11.1 1.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 AIF82298.1 - 0.32 10.7 2.6 0.21 11.3 0.4 1.7 1 1 1 2 2 2 0 BED zinc finger Cupredoxin_1 PF13473.1 AIF82300.1 - 5e-06 26.3 0.0 6.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain DUF202 PF02656.10 AIF82301.1 - 0.078 13.2 0.4 0.078 13.2 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) 7TM-7TMR_HD PF07698.6 AIF82301.1 - 0.23 10.8 7.9 0.31 10.4 5.5 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase TAT_signal PF10518.4 AIF82302.1 - 0.18 11.8 2.1 0.65 10.1 1.5 2.0 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence NTP_transf_5 PF14907.1 AIF82303.1 - 4.3e-07 29.5 0.0 5.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF1814 PF08843.6 AIF82303.1 - 3.3e-06 27.0 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF4269 PF14091.1 AIF82303.1 - 0.0041 17.0 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) DUF4194 PF13835.1 AIF82303.1 - 0.082 12.3 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) DUF4095 PF13338.1 AIF82305.1 - 0.086 12.9 0.3 0.14 12.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) DUF3444 PF11926.3 AIF82305.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) PIN PF01850.16 AIF82307.1 - 1.7e-09 38.0 1.9 2.2e-09 37.7 1.3 1.2 1 0 0 1 1 1 1 PIN domain PI31_Prot_N PF11566.3 AIF82308.1 - 0.07 12.7 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal UPF0253 PF06786.7 AIF82308.1 - 0.13 12.3 0.2 0.26 11.4 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0253) Arc PF03869.9 AIF82308.1 - 0.13 11.8 0.7 0.26 10.9 0.0 1.8 2 1 1 3 3 3 0 Arc-like DNA binding domain DUF3896 PF13035.1 AIF82308.1 - 0.14 12.2 0.3 0.26 11.3 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3896) DUF3596 PF12167.3 AIF82308.1 - 0.16 11.5 1.8 2.8 7.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3596) TrkH PF02386.11 AIF82312.1 - 2.1e-34 118.6 29.6 4e-34 117.7 11.3 2.6 1 1 0 2 2 2 2 Cation transport protein CBS PF00571.23 AIF82312.1 - 2.1e-19 69.0 0.9 1.7e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 CBS domain SpvD PF05563.7 AIF82312.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD Methyltransf_11 PF08241.7 AIF82313.1 - 1.5e-19 70.2 0.0 2.5e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF82313.1 - 1.5e-15 57.1 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF82313.1 - 1.9e-15 57.3 0.0 3.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF82313.1 - 5.4e-12 46.0 0.0 9.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82313.1 - 1.7e-11 44.0 0.0 2.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF82313.1 - 1.1e-10 41.7 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF82313.1 - 5e-10 38.8 0.0 7.3e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 AIF82313.1 - 1.1e-07 31.0 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 AIF82313.1 - 1.9e-07 30.6 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AIF82313.1 - 5.2e-07 29.7 0.1 2.2e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 AIF82313.1 - 3.2e-05 23.2 0.0 4.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 AIF82313.1 - 3.3e-05 23.5 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 AIF82313.1 - 4.9e-05 22.4 0.0 8.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 AIF82313.1 - 0.00048 19.8 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIF82313.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 AIF82313.1 - 0.0021 17.4 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 AIF82313.1 - 0.018 14.1 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 AIF82313.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB HATPase_c PF02518.21 AIF82315.1 - 8.9e-23 80.1 0.1 2.6e-22 78.6 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF82315.1 - 4.3e-10 39.4 0.6 1e-09 38.2 0.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AIF82315.1 - 0.00024 20.7 0.1 0.0006 19.4 0.1 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AIF82315.1 - 0.00053 19.6 0.6 0.0024 17.5 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cache_3 PF14827.1 AIF82315.1 - 0.0016 18.2 0.3 0.36 10.7 0.0 3.0 2 1 0 2 2 2 1 Sensory domain of two-component sensor kinase Orbi_VP7 PF00897.12 AIF82315.1 - 0.036 13.0 0.1 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 HATPase_c_2 PF13581.1 AIF82315.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Cache_1 PF02743.13 AIF82315.1 - 0.062 12.8 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Cache domain DUF2681 PF10883.3 AIF82315.1 - 6.2 7.0 8.3 14 5.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) RecX PF02631.11 AIF82316.1 - 0.0058 16.8 0.1 0.0084 16.3 0.1 1.3 1 0 0 1 1 1 1 RecX family DUF2127 PF09900.4 AIF82318.1 - 0.0044 17.0 16.3 0.096 12.7 6.5 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2127) Herpes_UL46 PF03387.9 AIF82318.1 - 0.19 9.9 1.1 0.22 9.7 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL46 protein DZR PF12773.2 AIF82320.1 - 0.62 9.9 3.8 5.1 7.0 2.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF1660 PF07874.6 AIF82320.1 - 0.95 9.7 4.4 8.3 6.7 0.3 2.1 1 1 1 2 2 2 0 Prophage protein (DUF1660) Mn_catalase PF05067.7 AIF82321.1 - 6.6e-71 238.3 0.0 7.9e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Manganese containing catalase DUF3764 PF12594.3 AIF82322.1 - 0.0071 16.0 0.2 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3764) ABM PF03992.11 AIF82322.1 - 0.023 14.7 0.1 0.061 13.3 0.0 1.8 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase GSDH PF07995.6 AIF82322.1 - 0.048 12.7 0.0 0.053 12.5 0.0 1.0 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Cytochrom_B562 PF07361.6 AIF82322.1 - 0.1 12.9 0.5 0.17 12.2 0.3 1.3 1 0 0 1 1 1 0 Cytochrome b562 DUF883 PF05957.8 AIF82323.1 - 0.0008 19.7 8.7 0.0008 19.7 6.0 1.7 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 AIF82323.1 - 0.0021 17.9 7.4 0.082 12.8 5.1 2.0 1 1 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phasin PF05597.6 AIF82323.1 - 0.0043 16.8 4.9 0.0045 16.7 3.4 1.1 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.2 AIF82323.1 - 0.016 15.5 11.5 0.04 14.2 8.0 1.6 1 1 0 1 1 1 0 YtxH-like protein HSP9_HSP12 PF04119.7 AIF82323.1 - 0.071 13.1 8.5 0.24 11.4 5.9 2.0 1 1 0 1 1 1 0 Heat shock protein 9/12 Synuclein PF01387.12 AIF82323.1 - 0.091 12.6 7.9 0.22 11.4 5.5 1.6 1 1 0 1 1 1 0 Synuclein Apolipoprotein PF01442.13 AIF82323.1 - 0.14 11.6 1.8 0.15 11.5 1.3 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 AIF82323.1 - 0.15 11.8 11.7 0.16 11.8 8.1 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) EspB PF05802.6 AIF82323.1 - 1.6 7.5 12.3 2.1 7.2 8.5 1.3 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF3359 PF11839.3 AIF82323.1 - 2.2 8.6 15.2 3.9 7.8 10.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3359) ISG65-75 PF11727.3 AIF82323.1 - 3.1 6.7 13.1 3.6 6.5 8.9 1.3 1 1 0 1 1 1 0 Invariant surface glycoprotein RRF PF01765.14 AIF82323.1 - 3.9 6.9 7.3 4 6.8 5.0 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DivIVA PF05103.8 AIF82323.1 - 4 7.5 8.4 5.4 7.0 5.8 1.2 1 0 0 1 1 1 0 DivIVA protein MT0933_antitox PF14013.1 AIF82323.1 - 5.7 7.1 17.7 28 4.9 12.3 1.9 1 1 0 1 1 1 0 MT0933-like antitoxin protein TM2 PF05154.11 AIF82327.1 - 0.0038 17.4 12.3 0.019 15.1 8.5 2.0 1 1 0 1 1 1 1 TM2 domain TspO_MBR PF03073.10 AIF82327.1 - 0.013 15.0 4.0 0.03 13.8 2.8 1.5 1 1 0 1 1 1 0 TspO/MBR family DUF3017 PF11222.3 AIF82327.1 - 0.036 13.8 1.0 0.053 13.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) DUF4234 PF14018.1 AIF82327.1 - 0.36 10.6 4.6 0.57 9.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Epiglycanin_C PF14654.1 AIF82328.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF575 PF04746.7 AIF82329.1 - 0.0021 18.0 0.0 0.0021 18.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF575) KaiB PF07689.7 AIF82330.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiB domain CAF1-p150_C2 PF15539.1 AIF82330.1 - 0.086 11.9 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Peptidase_M16 PF00675.15 AIF82330.1 - 0.11 12.2 0.2 3.6 7.3 0.0 2.1 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) Cupin_2 PF07883.6 AIF82333.1 - 5.4e-08 32.2 0.3 1.3e-07 30.9 0.1 1.7 2 1 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 AIF82333.1 - 9.2e-08 31.3 0.2 4.3e-06 26.0 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 AIF82333.1 - 0.0016 17.9 0.1 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Cupin CENP-C_C PF11699.3 AIF82333.1 - 0.096 12.6 0.0 0.26 11.3 0.0 1.7 1 1 1 2 2 2 0 Mif2/CENP-C like CMD PF02627.15 AIF82334.1 - 2.1e-14 53.1 0.0 3.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PIN PF01850.16 AIF82336.1 - 5.9e-10 39.5 0.4 8.7e-10 38.9 0.2 1.2 1 0 0 1 1 1 1 PIN domain tRNA-synt_2b PF00587.20 AIF82336.1 - 0.15 11.6 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) NUFIP1 PF10453.4 AIF82337.1 - 0.021 14.3 1.4 0.021 14.3 1.0 2.2 3 0 0 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Response_reg PF00072.19 AIF82339.1 - 1.6e-12 47.4 0.1 5.7e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain DZR PF12773.2 AIF82339.1 - 0.028 14.2 16.0 0.019 14.7 4.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 AIF82339.1 - 0.059 13.1 0.5 0.059 13.1 0.4 3.9 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Cys_rich_KTR PF14205.1 AIF82339.1 - 0.1 12.1 4.9 0.93 8.9 0.1 2.8 2 1 0 2 2 2 0 Cysteine-rich KTR zf-C2H2 PF00096.21 AIF82339.1 - 0.91 10.0 12.7 3.3 8.2 0.2 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-RING_3 PF14369.1 AIF82339.1 - 3 7.9 13.4 4.4 7.3 0.0 4.5 4 1 1 5 5 5 0 zinc-finger Zn-ribbon_8 PF09723.5 AIF82339.1 - 7.2 6.6 18.3 4.8 7.2 0.2 4.9 5 0 0 5 5 5 0 Zinc ribbon domain Glyco_tranf_2_3 PF13641.1 AIF82340.1 - 1.7e-33 116.3 0.0 2.7e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AIF82340.1 - 1.1e-30 106.5 0.0 1.9e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 AIF82340.1 - 1.3e-21 77.1 3.2 1.3e-21 77.1 2.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 AIF82340.1 - 2e-12 46.7 0.0 3.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF82340.1 - 1.6e-11 43.8 0.0 7.1e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 AIF82340.1 - 1.8e-10 39.8 4.2 0.00013 20.5 2.8 2.9 2 1 1 3 3 3 2 Chitin synthase Glyco_tranf_2_4 PF13704.1 AIF82340.1 - 0.0054 17.0 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Antitoxin-MazE PF04014.13 AIF82341.1 - 0.00016 21.3 0.2 0.00016 21.3 0.1 2.1 2 0 0 2 2 2 1 Antidote-toxin recognition MazE TrkA_N PF02254.13 AIF82341.1 - 0.058 13.3 0.1 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 AIF82341.1 - 0.12 12.8 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PIN PF01850.16 AIF82342.1 - 1.1e-11 45.1 0.1 1.2e-11 44.9 0.1 1.1 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.1 AIF82342.1 - 0.12 13.0 0.1 0.2 12.3 0.1 1.6 1 1 0 1 1 1 0 PIN domain DivIC PF04977.10 AIF82343.1 - 0.023 14.1 2.4 0.035 13.5 1.6 1.3 1 0 0 1 1 1 0 Septum formation initiator Cas_Csy4 PF09618.5 AIF82343.1 - 0.085 12.6 1.4 0.093 12.5 1.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) TMF_DNA_bd PF12329.3 AIF82343.1 - 0.14 11.9 0.6 0.14 11.9 0.4 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RecX PF02631.11 AIF82344.1 - 0.03 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 RecX family Pyridox_oxidase PF01243.15 AIF82345.1 - 2.1e-14 53.3 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Methyltransf_31 PF13847.1 AIF82346.1 - 2.8e-18 65.9 0.0 5.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF82346.1 - 2.1e-16 60.4 0.0 5.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF82346.1 - 8.4e-12 45.4 0.0 1.5e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82346.1 - 7.7e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF82346.1 - 1.7e-10 41.2 0.0 3.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AIF82346.1 - 4.4e-09 35.6 0.0 8.3e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 AIF82346.1 - 4e-08 33.5 0.0 7.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF82346.1 - 2.6e-07 30.1 0.0 4.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AIF82346.1 - 5.1e-06 26.5 0.0 2e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 AIF82346.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 AIF82346.1 - 7.8e-05 21.8 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 AIF82346.1 - 0.001 18.1 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 AIF82346.1 - 0.0024 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AIF82346.1 - 0.0037 16.4 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 AIF82346.1 - 0.031 13.2 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 AIF82346.1 - 0.033 13.3 0.0 0.075 12.2 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase TehB PF03848.9 AIF82346.1 - 0.037 13.1 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 AIF82346.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation PF08100.6 AIF82346.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain tRNA_U5-meth_tr PF05958.6 AIF82346.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase US22 PF02393.11 AIF82347.1 - 0.029 14.3 0.1 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 US22 like Crust_neurohorm PF01147.12 AIF82347.1 - 0.057 12.7 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family DUF457 PF04307.9 AIF82348.1 - 3.5e-08 32.9 15.8 5.2e-08 32.3 10.9 1.5 1 1 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) Arch_flagellin PF01917.11 AIF82348.1 - 0.017 14.7 0.1 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Archaebacterial flagellin DUF4342 PF14242.1 AIF82348.1 - 0.2 11.4 3.1 0.72 9.6 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Zn_ribbon_2 PF12674.2 AIF82349.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain PIN PF01850.16 AIF82350.1 - 1e-14 54.8 0.5 1.1e-14 54.7 0.4 1.0 1 0 0 1 1 1 1 PIN domain DUF217 PF02697.9 AIF82351.1 - 2.8e-15 56.3 0.8 3e-15 56.2 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1753 Imm41 PF15583.1 AIF82351.1 - 0.082 12.7 0.2 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 41 DUF217 PF02697.9 AIF82352.1 - 7.9e-10 38.8 1.7 1.1e-09 38.4 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1753 PIN PF01850.16 AIF82353.1 - 2.3e-12 47.2 0.1 2.6e-12 47.1 0.1 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.1 AIF82353.1 - 0.032 14.9 0.2 0.038 14.6 0.1 1.1 1 0 0 1 1 1 0 PIN domain adh_short_C2 PF13561.1 AIF82353.1 - 0.069 12.9 0.0 0.091 12.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Arginase PF00491.16 AIF82354.1 - 0.03 13.5 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 Arginase family Na_H_Exchanger PF00999.16 AIF82357.1 - 0.017 13.6 1.7 0.02 13.4 1.1 1.0 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family IncA PF04156.9 AIF82357.1 - 0.018 14.6 0.1 0.02 14.5 0.0 1.0 1 0 0 1 1 1 0 IncA protein SHR3_chaperone PF08229.6 AIF82357.1 - 0.02 13.8 0.2 0.023 13.6 0.1 1.0 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4642 PF15484.1 AIF82357.1 - 0.036 14.0 0.1 0.041 13.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DivIC PF04977.10 AIF82357.1 - 0.074 12.5 1.2 0.1 12.1 0.8 1.2 1 0 0 1 1 1 0 Septum formation initiator TMEM154 PF15102.1 AIF82357.1 - 0.086 12.5 3.0 0.19 11.4 2.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.5 AIF82357.1 - 0.2 11.6 0.2 0.2 11.6 0.1 1.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3498 PF12004.3 AIF82357.1 - 0.2 10.7 3.4 0.25 10.4 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Sulfate_tra_GLY PF13792.1 AIF82357.1 - 0.35 10.5 2.9 0.48 10.1 2.0 1.2 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif DUF4599 PF15371.1 AIF82357.1 - 1.1 9.4 5.3 1.4 9.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) Na_H_Exchanger PF00999.16 AIF82358.1 - 0.012 14.2 0.8 0.012 14.1 0.6 1.0 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family PIN PF01850.16 AIF82359.1 - 9.7e-20 71.1 0.2 1.1e-19 70.9 0.1 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.1 AIF82359.1 - 0.0023 18.5 0.0 0.0032 18.1 0.0 1.2 1 0 0 1 1 1 1 PIN domain DUF4411 PF14367.1 AIF82359.1 - 0.0091 15.7 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4411) Antitoxin-MazE PF04014.13 AIF82360.1 - 7.4e-11 41.5 2.0 1.3e-10 40.7 1.4 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE Fapy_DNA_glyco PF01149.19 AIF82361.1 - 0.028 14.7 0.0 0.38 11.1 0.0 2.0 1 1 1 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain MannoseP_isomer PF01050.13 AIF82362.1 - 3.5e-23 81.8 0.0 3.9e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_2 PF07883.6 AIF82362.1 - 4.4e-10 38.9 0.0 6.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain FdtA PF05523.6 AIF82362.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 WxcM-like, C-terminal AraC_binding PF02311.14 AIF82362.1 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 AIF82362.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 AIF82362.1 - 0.0089 15.6 0.0 0.0091 15.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 AIF82362.1 - 0.013 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Cupin CENP-C_C PF11699.3 AIF82362.1 - 0.031 14.2 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like DUF1498 PF07385.7 AIF82362.1 - 0.045 12.8 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) DUF4384 PF14326.1 AIF82362.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4384) UPF0139 PF03669.8 AIF82364.1 - 0.0013 18.2 1.5 0.048 13.1 0.0 3.4 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0139) PMT_2 PF13231.1 AIF82364.1 - 0.0018 18.2 25.5 0.0018 18.2 17.7 5.1 3 2 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Imm10 PF15562.1 AIF82366.1 - 0.15 11.8 0.2 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 10 N6_Mtase PF02384.11 AIF82367.1 - 5.7e-31 107.7 0.0 3.1e-30 105.3 0.0 2.1 2 1 0 2 2 2 1 N-6 DNA Methylase HSDR_N_2 PF13588.1 AIF82367.1 - 1.4e-29 102.0 0.0 3.3e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Methyltransf_26 PF13659.1 AIF82367.1 - 1.7e-11 44.1 0.0 2.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AIF82367.1 - 5.1e-09 35.9 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 AIF82367.1 - 0.00022 20.6 0.0 0.023 14.0 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase small domain Eco57I PF07669.6 AIF82367.1 - 0.00042 20.6 0.0 0.0055 17.0 0.0 2.8 2 1 0 2 2 2 1 Eco57I restriction-modification methylase Methyltransf_31 PF13847.1 AIF82367.1 - 0.018 14.6 0.0 0.24 10.9 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain HSDR_N PF04313.9 AIF82367.1 - 0.038 13.7 0.0 0.4 10.3 0.0 2.4 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Methylase_S PF01420.14 AIF82368.1 - 1.5e-08 34.7 0.2 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain Plasmid_stabil PF05016.9 AIF82369.1 - 1.1e-07 32.1 0.5 2.2e-07 31.1 0.1 1.6 1 1 1 2 2 2 1 Plasmid stabilisation system protein Gp49 PF05973.9 AIF82369.1 - 0.0008 19.3 0.1 0.0016 18.4 0.0 1.5 1 1 1 2 2 2 1 Phage derived protein Gp49-like (DUF891) Plasmid_Txe PF06769.8 AIF82369.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Plasmid encoded toxin Txe FlbD PF06289.6 AIF82369.1 - 0.16 11.3 0.5 5.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein (FlbD) BCL_N PF04714.8 AIF82369.1 - 0.18 11.4 1.1 0.81 9.2 0.1 2.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region EF_assoc_1 PF08355.7 AIF82370.1 - 0.24 10.7 1.4 1.3 8.3 0.0 2.4 2 1 1 3 3 3 0 EF hand associated DDE_Tnp_1 PF01609.16 AIF82371.1 - 1.4e-17 63.9 0.6 3.3e-17 62.7 0.4 1.6 1 1 0 1 1 1 1 Transposase DDE domain DUF4042 PF13251.1 AIF82373.1 - 0.099 12.1 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) MRL1 PF13003.2 AIF82373.1 - 0.11 12.2 0.9 5.6 6.7 0.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L1 PLDc_2 PF13091.1 AIF82374.1 - 1.9e-10 40.5 1.2 3.3e-10 39.7 0.9 1.4 1 0 0 1 1 1 1 PLD-like domain Kv2channel PF03521.9 AIF82374.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel DUF1814 PF08843.6 AIF82376.1 - 1.1e-30 107.1 0.0 1.7e-30 106.5 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF4095 PF13338.1 AIF82377.1 - 1.8e-23 83.0 0.0 2.8e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4095) DUF2624 PF11116.3 AIF82377.1 - 0.15 12.6 0.1 13 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) AAA_30 PF13604.1 AIF82378.1 - 8.5e-19 67.9 0.0 3.1e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 AIF82378.1 - 1.5e-13 50.7 0.0 3.9e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 AIF82378.1 - 3.1e-12 46.5 0.1 4.5e-07 29.6 0.1 2.4 1 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 AIF82378.1 - 1.6e-11 44.2 0.1 8.2e-05 22.2 0.0 3.8 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 AIF82378.1 - 5.2e-09 35.7 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 AIF82378.1 - 2.2e-06 27.2 0.9 0.029 13.6 0.1 2.8 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 AIF82378.1 - 9.3e-05 22.5 0.3 0.0038 17.3 0.2 3.2 2 1 0 2 2 2 1 AAA domain HHH_4 PF14490.1 AIF82378.1 - 0.00049 19.8 0.2 0.015 15.0 0.1 2.8 1 1 0 1 1 1 1 Helix-hairpin-helix containing domain DEAD PF00270.24 AIF82378.1 - 0.0006 19.3 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 AIF82378.1 - 0.0027 16.7 0.2 0.1 11.5 0.2 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 AIF82378.1 - 0.0057 15.5 0.0 0.0099 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.9 AIF82378.1 - 0.011 15.4 0.1 0.11 12.1 0.0 2.3 1 1 0 1 1 1 0 Helicase CbiA PF01656.18 AIF82378.1 - 0.013 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Herpes_Helicase PF02689.9 AIF82378.1 - 0.02 12.6 0.2 0.34 8.5 0.0 2.6 3 0 0 3 3 3 0 Helicase PhoH PF02562.11 AIF82378.1 - 0.033 13.4 0.1 0.15 11.2 0.1 2.0 1 1 0 1 1 1 0 PhoH-like protein TrwB_AAD_bind PF10412.4 AIF82378.1 - 0.044 12.3 0.0 0.12 10.9 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 AIF82378.1 - 0.13 12.2 0.0 1 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 AIF82378.1 - 0.19 11.0 0.0 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2592 PF10766.4 AIF82379.1 - 0.11 11.8 5.3 0.28 10.5 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) AAA_16 PF13191.1 AIF82381.1 - 2.9e-05 24.1 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 AIF82381.1 - 7.7e-05 22.4 0.4 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 AIF82381.1 - 0.00072 19.6 0.1 0.0065 16.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AIF82381.1 - 0.013 14.9 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 AIF82381.1 - 0.017 15.0 0.1 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIF82381.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 AIF82381.1 - 0.029 13.5 0.1 0.054 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 AIF82381.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TrmB PF01978.14 AIF82381.1 - 0.061 13.0 1.1 0.33 10.6 0.5 2.5 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB AAA_35 PF14516.1 AIF82381.1 - 0.079 11.5 0.0 0.22 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 AIF82381.1 - 0.095 13.0 2.4 0.093 13.0 0.4 1.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AIF82381.1 - 0.11 12.0 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Herpes_UL79 PF03049.9 AIF82383.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 UL79 family ParBc PF02195.13 AIF82386.1 - 9.2e-23 80.1 0.0 3.6e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain KorB PF08535.5 AIF82386.1 - 3.7e-06 27.0 1.2 5.9e-06 26.3 0.3 1.8 2 0 0 2 2 2 1 KorB domain zf-C2H2_2 PF12756.2 AIF82387.1 - 0.0092 16.0 0.1 0.01 15.9 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AIF82387.1 - 0.06 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Glycos_transf_2 PF00535.21 AIF82388.1 - 6.1e-35 120.3 0.1 1.3e-34 119.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIF82388.1 - 2.4e-29 102.7 0.0 5.4e-29 101.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 AIF82388.1 - 5e-22 77.9 1.2 4.8e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AIF82388.1 - 1.2e-16 61.0 9.6 2.6e-16 59.8 2.9 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 AIF82388.1 - 7.8e-10 38.3 0.2 1.1e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF82388.1 - 3.1e-07 29.7 0.0 5.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transferase PF00483.18 AIF82388.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Glyco_tranf_2_4 PF13704.1 AIF82388.1 - 0.0082 16.4 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Polysacc_deac_1 PF01522.16 AIF82389.1 - 6.7e-12 45.1 0.0 1.2e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase UDPG_MGDP_dh PF00984.14 AIF82390.1 - 3e-18 65.8 0.0 5.8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.9 AIF82390.1 - 4.3e-09 36.0 0.0 0.00021 20.7 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 AIF82390.1 - 9.1e-05 22.3 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 AIF82390.1 - 0.0002 21.0 0.1 0.00049 19.7 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 AIF82390.1 - 0.00025 20.2 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPMT PF05724.6 AIF82390.1 - 0.0047 16.3 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TrkA_N PF02254.13 AIF82390.1 - 0.033 14.1 0.2 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_23 PF13489.1 AIF82390.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AIF82390.1 - 0.1 13.2 0.0 0.84 10.2 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Antimicrobial20 PF08256.6 AIF82390.1 - 2.9 8.4 4.9 63 4.3 0.8 3.2 3 0 0 3 3 3 0 Aurein-like antibiotic peptide CHB_HEX_C PF03174.8 AIF82392.1 - 9.9e-41 137.4 30.2 4e-21 74.6 7.7 2.9 2 0 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 AIF82392.1 - 2.2e-37 126.6 26.5 3e-19 68.5 6.0 3.0 2 0 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIF82392.1 - 6.9e-34 115.7 26.2 3.2e-17 62.3 6.5 2.8 2 0 0 2 2 2 2 Fn3 associated Polysacc_deac_1 PF01522.16 AIF82392.1 - 1e-11 44.5 0.0 2.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase TrkA_C PF02080.16 AIF82392.1 - 0.061 12.9 0.0 28 4.3 0.0 3.6 4 0 0 4 4 4 0 TrkA-C domain Copper-bind PF00127.15 AIF82395.1 - 3.5e-05 23.9 3.8 0.0037 17.4 0.1 2.7 3 0 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF82395.1 - 0.0026 17.6 0.1 0.089 12.6 0.0 2.7 2 1 1 3 3 3 1 Cupredoxin-like domain LIM PF00412.17 AIF82396.1 - 0.00067 19.6 1.7 0.0015 18.5 1.1 1.6 1 1 0 1 1 1 1 LIM domain zinc_ribbon_4 PF13717.1 AIF82396.1 - 0.0081 15.8 0.8 4.3 7.1 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF82396.1 - 0.012 15.2 0.8 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.3 AIF82396.1 - 0.12 12.2 0.4 8.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.1 AIF82396.1 - 0.14 11.7 3.0 8.8 5.9 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AIF82396.1 - 0.2 11.1 6.4 0.64 9.5 0.2 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.1 AIF82396.1 - 0.29 10.8 9.4 9.3 6.0 0.2 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 AIF82396.1 - 0.34 10.7 4.7 4.3 7.2 3.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon XPA_N PF01286.13 AIF82396.1 - 0.76 9.5 3.3 25 4.6 0.1 3.0 3 0 0 3 3 3 0 XPA protein N-terminal Yippee-Mis18 PF03226.9 AIF82396.1 - 0.85 9.7 7.6 35 4.5 5.3 2.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1272 PF06906.6 AIF82396.1 - 1.4 8.8 5.7 1.4 8.8 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-PARP PF00645.13 AIF82396.1 - 1.5 9.1 8.1 0.24 11.6 1.4 2.4 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF2296 PF10058.4 AIF82396.1 - 1.7 8.4 5.4 0.2 11.4 0.9 1.5 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) C1_1 PF00130.17 AIF82396.1 - 3.6 7.3 10.7 10 5.9 0.5 2.8 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S27e PF01667.12 AIF82396.1 - 3.7 7.1 9.7 1.7 8.2 0.4 3.0 2 1 1 3 3 3 0 Ribosomal protein S27 zf-ribbon_3 PF13248.1 AIF82396.1 - 5.1 6.4 8.6 35 3.7 3.5 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.8 AIF82396.1 - 5.4 6.8 7.8 3.5 7.4 0.1 2.6 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Cu-oxidase_3 PF07732.10 AIF82397.1 - 1.4e-23 82.8 0.4 2.9e-20 72.1 0.1 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AIF82397.1 - 2.5e-15 56.2 9.8 2.2e-06 27.2 0.0 4.5 4 1 0 4 4 4 3 Multicopper oxidase Cupredoxin_1 PF13473.1 AIF82397.1 - 3.2e-08 33.4 0.0 7.4e-06 25.8 0.0 3.6 3 0 0 3 3 3 1 Cupredoxin-like domain Copper-bind PF00127.15 AIF82397.1 - 4.6e-07 29.9 6.5 2e-06 27.9 0.0 4.0 2 2 1 3 3 3 1 Copper binding proteins, plastocyanin/azurin family HABP4_PAI-RBP1 PF04774.10 AIF82397.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.7 2 1 1 3 3 3 0 Hyaluronan / mRNA binding family GCR1_C PF12550.3 AIF82398.1 - 0.061 13.1 0.1 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes TSCPD PF12637.2 AIF82398.1 - 0.093 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 TSCPD domain DZR PF12773.2 AIF82400.1 - 0.00025 20.7 0.6 0.00033 20.4 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF82400.1 - 0.00054 19.0 1.4 0.00087 18.4 0.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF82400.1 - 0.0042 16.5 2.6 0.0062 15.9 1.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-DHHC PF01529.15 AIF82400.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF202 PF02656.10 AIF82407.1 - 1.1e-16 60.7 3.3 1.1e-16 60.7 2.3 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF996 PF06195.8 AIF82407.1 - 0.0039 17.1 3.1 0.0045 16.9 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF996) TctB PF07331.6 AIF82407.1 - 0.0064 16.1 1.9 0.02 14.5 0.1 2.1 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.1 AIF82407.1 - 0.018 14.4 1.2 0.035 13.5 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TauE PF01925.14 AIF82407.1 - 0.035 13.5 3.7 0.093 12.1 2.6 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE YtpI PF14007.1 AIF82407.1 - 0.23 11.3 2.8 0.64 9.9 0.1 2.4 2 1 1 3 3 3 0 YtpI-like protein DUF3185 PF11381.3 AIF82407.1 - 0.33 10.7 0.2 0.33 10.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF4199 PF13858.1 AIF82407.1 - 0.38 10.6 5.7 0.08 12.8 0.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) Tetraspannin PF00335.15 AIF82407.1 - 3.4 6.8 5.5 1.7 7.8 1.4 1.8 1 1 1 2 2 2 0 Tetraspanin family RHH_1 PF01402.16 AIF82408.1 - 1.2e-06 28.1 1.2 1.4e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family RHH_4 PF13467.1 AIF82408.1 - 0.015 15.2 0.1 0.039 13.8 0.0 1.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain DUF2610 PF11020.3 AIF82408.1 - 0.074 12.8 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) DUF4398 PF14346.1 AIF82411.1 - 0.043 13.8 0.3 0.05 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF2564 PF10819.3 AIF82411.1 - 0.14 12.2 0.6 0.24 11.5 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) Ribosomal_L12 PF00542.14 AIF82411.1 - 0.53 10.3 5.0 0.66 10.0 3.4 1.2 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain SNF2_N PF00176.18 AIF82412.1 - 0.018 13.8 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ead_Ea22 PF13935.1 AIF82412.1 - 0.058 13.7 0.0 0.98 9.7 0.0 1.9 1 1 0 2 2 2 0 Ead/Ea22-like protein Peptidase_M50 PF02163.17 AIF82413.1 - 3.4e-23 81.6 7.2 2.2e-20 72.4 5.0 2.4 1 1 0 1 1 1 1 Peptidase family M50 CBS PF00571.23 AIF82413.1 - 1.2e-17 63.4 0.3 1.7e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain Peptidase_M50B PF13398.1 AIF82413.1 - 0.00067 19.0 0.3 0.00067 19.0 0.2 2.4 2 1 0 3 3 3 1 Peptidase M50B-like PPC PF04151.10 AIF82416.1 - 0.019 15.9 0.4 0.12 13.3 0.2 2.5 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain HTH_20 PF12840.2 AIF82417.1 - 1.2e-10 41.0 0.6 2.2e-10 40.1 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AIF82417.1 - 8.7e-08 31.4 0.0 1.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 AIF82417.1 - 9.6e-08 31.5 0.3 1.9e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF82417.1 - 0.00013 21.6 0.1 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF82417.1 - 0.00086 18.9 0.0 0.0034 17.0 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 AIF82417.1 - 0.024 14.4 0.0 0.039 13.8 0.0 1.5 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC Sigma70_r4_2 PF08281.7 AIF82417.1 - 0.088 12.2 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.7 AIF82417.1 - 0.15 11.7 0.3 0.53 9.9 0.1 1.9 2 0 0 2 2 2 0 HTH domain HATPase_c PF02518.21 AIF82420.1 - 1.7e-22 79.2 0.6 7e-22 77.2 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF82420.1 - 4.7e-12 45.7 2.3 1.1e-11 44.5 0.0 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AIF82420.1 - 0.00059 19.4 0.1 0.0028 17.3 0.1 2.2 1 0 0 1 1 1 1 GHKL domain SIMPL PF04402.9 AIF82420.1 - 0.0025 17.7 1.1 0.0025 17.7 0.7 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF541) HATPase_c_3 PF13589.1 AIF82420.1 - 0.025 14.2 0.0 0.076 12.6 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phtf-FEM1B_bdg PF12129.3 AIF82420.1 - 0.039 13.2 0.2 0.082 12.2 0.1 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor PLDc_2 PF13091.1 AIF82420.1 - 0.42 10.3 2.3 15 5.3 0.0 3.2 3 1 0 3 3 3 0 PLD-like domain Methyltransf_31 PF13847.1 AIF82420.1 - 1 8.9 5.9 16 5.0 0.1 3.6 4 1 0 4 4 4 0 Methyltransferase domain rve PF00665.21 AIF82423.1 - 4.7e-21 75.1 0.0 2.1e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 AIF82423.1 - 1.8e-13 50.1 0.1 1.8e-12 46.9 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 AIF82423.1 - 5.6e-13 49.0 0.3 1.8e-11 44.1 0.0 2.5 3 0 0 3 3 3 1 Winged helix-turn helix rve_3 PF13683.1 AIF82423.1 - 1.1e-10 40.9 0.0 9.4e-10 37.8 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.1 AIF82423.1 - 1.2e-09 37.4 0.8 3.7e-08 32.7 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.1 AIF82423.1 - 1.9e-09 37.7 0.0 1.9e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 HTH_32 PF13565.1 AIF82423.1 - 2.4e-09 37.8 0.5 2.4e-09 37.8 0.3 2.2 3 0 0 3 3 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 AIF82423.1 - 1.3e-05 25.0 0.0 3.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_21 PF13276.1 AIF82423.1 - 2.3e-05 24.3 2.9 2.3e-05 24.3 2.0 2.5 1 1 1 2 2 2 1 HTH-like domain HTH_7 PF02796.10 AIF82423.1 - 0.0012 18.6 0.1 0.0037 17.0 0.0 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain of resolvase HTH_17 PF12728.2 AIF82423.1 - 0.002 18.3 2.3 0.043 14.0 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.11 AIF82423.1 - 0.0022 17.6 1.5 0.36 10.5 0.0 2.6 2 0 0 2 2 2 1 Transposase rve_2 PF13333.1 AIF82423.1 - 0.038 14.0 0.1 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Terminase_5 PF06056.7 AIF82423.1 - 0.056 13.0 0.1 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1_2 PF13022.1 AIF82423.1 - 0.088 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase VirArc_Nuclease PF12187.3 AIF82426.1 - 0.093 12.1 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Viral/Archaeal nuclease Cupin_3 PF05899.7 AIF82432.1 - 3.6e-07 29.4 0.1 1.1e-06 27.9 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 AIF82432.1 - 3.5e-06 26.4 0.0 6.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AIF82432.1 - 0.038 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding_2 PF14525.1 AIF82432.1 - 0.075 12.6 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 AraC-binding-like domain Lon_C PF05362.8 AIF82433.1 - 2.1e-10 40.2 0.2 3.3e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 AIF82433.1 - 0.0061 16.0 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase FtsL PF04999.8 AIF82433.1 - 0.025 14.2 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Cell division protein FtsL DUF4363 PF14276.1 AIF82433.1 - 0.036 13.7 0.3 0.068 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) CASP_C PF08172.7 AIF82433.1 - 0.067 12.2 3.6 0.11 11.5 2.5 1.3 1 0 0 1 1 1 0 CASP C terminal AAA PF00004.24 AIF82434.1 - 2.5e-100 331.8 0.1 1.9e-49 167.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AIF82434.1 - 1.7e-21 75.9 0.3 4.9e-21 74.4 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AIF82434.1 - 4.9e-17 62.3 0.0 3e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AIF82434.1 - 4.9e-15 55.2 0.0 1.7e-08 33.8 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AIF82434.1 - 2.2e-13 50.4 0.3 6.3e-05 23.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AIF82434.1 - 1.6e-12 47.8 0.0 7.1e-06 26.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 AIF82434.1 - 2.5e-12 47.6 0.0 3.8e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AIF82434.1 - 3.8e-11 42.8 0.5 0.00027 20.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AIF82434.1 - 2.2e-10 39.8 0.1 0.001 17.8 0.0 3.2 3 0 0 3 3 3 2 TIP49 C-terminus Zeta_toxin PF06414.7 AIF82434.1 - 2.2e-10 39.9 0.0 0.00024 20.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 AIF82434.1 - 6.6e-10 39.0 0.0 8.3e-05 22.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 AIF82434.1 - 8.4e-10 38.1 0.0 2.7e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 AIF82434.1 - 5.8e-09 35.5 0.5 0.00088 18.9 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 AIF82434.1 - 5.9e-09 35.9 0.0 0.00038 20.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AIF82434.1 - 1.7e-08 34.0 0.2 0.0042 16.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 AIF82434.1 - 1.6e-07 30.9 6.3 0.12 11.7 0.1 4.3 2 2 1 4 4 4 3 AAA domain Mg_chelatase PF01078.16 AIF82434.1 - 1.7e-07 30.6 0.8 0.0059 15.7 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AIF82434.1 - 7.7e-07 29.2 0.0 0.055 13.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 AIF82434.1 - 8.7e-07 29.3 0.6 0.011 16.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 AIF82434.1 - 1.7e-06 28.1 0.0 0.024 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 AIF82434.1 - 2.6e-06 27.1 0.1 0.26 10.9 0.0 3.7 4 0 0 4 4 4 2 NACHT domain AAA_3 PF07726.6 AIF82434.1 - 3.8e-06 26.5 0.0 0.086 12.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AIF82434.1 - 5.2e-06 26.0 0.0 0.17 11.3 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 AIF82434.1 - 6.1e-06 26.1 0.1 0.0067 16.1 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 AIF82434.1 - 2.1e-05 24.2 0.3 0.052 13.1 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 AIF82434.1 - 3.9e-05 23.3 0.1 0.23 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 AIF82434.1 - 4e-05 22.9 0.2 0.13 11.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein KaiC PF06745.8 AIF82434.1 - 4.3e-05 22.7 0.9 0.29 10.2 0.0 3.1 2 1 1 3 3 3 2 KaiC Sigma54_activ_2 PF14532.1 AIF82434.1 - 0.00011 22.2 0.0 0.48 10.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AIF82434.1 - 0.00011 21.1 0.1 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 AIF82434.1 - 0.00012 21.7 0.0 0.053 13.1 0.0 3.1 2 1 1 3 3 3 1 Bacterial dnaA protein NB-ARC PF00931.17 AIF82434.1 - 0.00016 20.6 0.0 0.1 11.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.1 AIF82434.1 - 0.00024 20.7 0.2 0.34 10.4 0.0 2.6 2 2 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 AIF82434.1 - 0.00027 20.6 4.4 1.1 8.9 0.0 4.1 3 1 1 4 4 3 1 NTPase DUF815 PF05673.8 AIF82434.1 - 0.00037 19.4 0.0 0.54 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF2075 PF09848.4 AIF82434.1 - 0.00041 19.4 0.3 0.092 11.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 AIF82434.1 - 0.00045 20.0 0.0 0.72 9.6 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 AIF82434.1 - 0.00067 19.2 0.0 0.85 9.0 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 AIF82434.1 - 0.00072 19.2 0.2 2.9 7.4 0.0 3.3 3 1 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 AIF82434.1 - 0.00093 19.4 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter T2SE PF00437.15 AIF82434.1 - 0.0017 17.3 0.0 1.5 7.6 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein UPF0079 PF02367.12 AIF82434.1 - 0.0024 17.5 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 AIF82434.1 - 0.0044 15.8 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 1 AFG1-like ATPase SKI PF01202.17 AIF82434.1 - 0.0065 16.3 0.1 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.13 AIF82434.1 - 0.011 15.3 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 AIF82434.1 - 0.011 15.6 0.0 0.53 10.1 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family MCM PF00493.18 AIF82434.1 - 0.026 13.3 0.0 2.8 6.6 0.0 2.7 3 0 0 3 3 2 0 MCM2/3/5 family Guanylate_kin PF00625.16 AIF82434.1 - 0.026 13.9 0.1 7 6.0 0.0 3.3 2 1 1 3 3 3 0 Guanylate kinase DAP3 PF10236.4 AIF82434.1 - 0.05 12.5 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Torsin PF06309.6 AIF82434.1 - 0.062 13.1 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Torsin KTI12 PF08433.5 AIF82434.1 - 0.084 12.0 0.1 14 4.8 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IPT PF01745.11 AIF82434.1 - 0.12 11.5 0.4 5.6 6.0 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase HSP20 PF00011.16 AIF82435.1 - 2.9e-09 36.6 3.3 5.6e-08 32.5 2.3 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 AIF82435.1 - 1.3e-06 28.0 0.1 1.6e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 AIF82435.1 - 0.034 14.7 2.2 0.1 13.1 0.9 2.1 2 1 1 3 3 3 0 CS domain HTH_20 PF12840.2 AIF82436.1 - 1.8e-16 59.6 1.3 7.3e-16 57.7 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF82436.1 - 7.3e-13 47.9 3.8 3.8e-12 45.6 0.0 2.9 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AIF82436.1 - 4.3e-08 32.4 0.4 6.3e-07 28.6 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 AIF82436.1 - 1.2e-07 31.3 3.2 0.0002 21.0 0.0 3.0 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 AIF82436.1 - 2.3e-07 30.4 2.0 2.9e-06 26.9 0.3 2.8 2 1 0 2 2 2 1 Transcriptional regulator PadR-like family MarR_2 PF12802.2 AIF82436.1 - 2.8e-06 26.9 0.0 8.2e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.7 AIF82436.1 - 2.7e-05 23.7 0.6 0.00057 19.4 0.1 3.0 3 0 0 3 3 3 1 HTH domain MarR PF01047.17 AIF82436.1 - 5.3e-05 22.8 0.3 0.00059 19.5 0.1 2.4 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 AIF82436.1 - 0.00019 21.6 0.2 0.0052 17.0 0.0 2.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_12 PF08461.5 AIF82436.1 - 0.00059 19.5 0.2 0.0028 17.3 0.0 2.3 2 1 0 2 2 1 1 Ribonuclease R winged-helix domain ArsR PF09824.4 AIF82436.1 - 0.00085 18.6 2.1 0.0029 16.9 0.1 2.4 1 1 1 2 2 2 1 ArsR transcriptional regulator HxlR PF01638.12 AIF82436.1 - 0.0011 18.5 0.5 0.0037 16.8 0.0 2.1 2 1 0 2 2 2 1 HxlR-like helix-turn-helix DUF2250 PF10007.4 AIF82436.1 - 0.0018 18.1 4.2 0.0031 17.3 0.2 3.0 3 1 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2250) DUF1759 PF03564.10 AIF82436.1 - 0.0027 17.5 3.1 0.0051 16.6 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Rrf2 PF02082.15 AIF82436.1 - 0.0033 17.5 1.2 0.037 14.1 0.0 2.6 3 0 0 3 3 2 1 Transcriptional regulator HTH_34 PF13601.1 AIF82436.1 - 0.0037 17.2 0.4 0.016 15.2 0.0 2.2 2 1 1 3 3 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.5 AIF82436.1 - 0.0071 15.9 0.3 0.021 14.3 0.0 2.0 2 0 0 2 2 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.1 AIF82436.1 - 0.04 13.7 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_29 PF13551.1 AIF82436.1 - 0.041 14.0 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 Winged helix-turn helix TFIIE_alpha PF02002.12 AIF82436.1 - 0.048 13.1 1.6 0.2 11.1 0.1 2.4 2 1 0 2 2 2 0 TFIIE alpha subunit LexA_DNA_bind PF01726.11 AIF82436.1 - 0.059 12.9 0.1 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 LexA DNA binding domain FTA4 PF13093.1 AIF82436.1 - 0.08 12.3 6.8 0.12 11.8 4.7 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HTH_7 PF02796.10 AIF82436.1 - 0.083 12.7 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase AAA_13 PF13166.1 AIF82436.1 - 0.084 11.3 6.3 0.1 11.0 4.4 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 AIF82436.1 - 0.086 12.9 4.1 1.6 8.8 0.1 2.6 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family Fe_dep_repress PF01325.14 AIF82436.1 - 0.087 12.7 1.4 0.65 9.9 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain ParB PF08775.5 AIF82436.1 - 0.11 12.8 2.5 0.33 11.2 0.2 2.4 1 1 1 2 2 2 0 ParB family ThylakoidFormat PF11264.3 AIF82436.1 - 0.11 12.1 5.6 0.22 11.0 3.7 1.7 1 1 0 1 1 1 0 Thylakoid formation protein Reo_sigmaC PF04582.7 AIF82436.1 - 0.11 11.6 1.8 0.16 11.1 1.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 AIF82436.1 - 0.15 12.2 0.3 0.15 12.2 0.2 2.4 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HTH_1 PF00126.22 AIF82436.1 - 0.17 11.6 1.2 0.26 11.0 0.1 1.9 2 0 0 2 2 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF4140 PF13600.1 AIF82436.1 - 0.19 12.2 1.2 0.38 11.2 0.2 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Dam1 PF08653.5 AIF82436.1 - 0.24 11.1 3.0 0.41 10.4 0.3 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 Prefoldin_2 PF01920.15 AIF82436.1 - 0.27 11.0 8.3 0.19 11.4 0.4 2.9 2 1 1 3 3 3 0 Prefoldin subunit DUF342 PF03961.8 AIF82436.1 - 0.34 9.2 4.7 0.46 8.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CorA PF01544.13 AIF82436.1 - 0.63 9.0 5.7 7 5.5 3.9 2.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SlyX PF04102.7 AIF82436.1 - 0.7 10.3 3.3 8.5 6.8 0.1 2.7 3 0 0 3 3 2 0 SlyX Syntaxin-6_N PF09177.6 AIF82436.1 - 0.88 10.0 4.2 0.49 10.8 0.5 2.3 2 1 1 3 3 2 0 Syntaxin 6, N-terminal ACCA PF03255.9 AIF82436.1 - 1.1 8.8 5.7 0.41 10.1 0.4 2.4 2 1 1 3 3 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit IncA PF04156.9 AIF82436.1 - 1.6 8.2 10.6 0.63 9.5 4.9 2.1 1 1 1 2 2 2 0 IncA protein Cpn60_TCP1 PF00118.19 AIF82437.1 - 1.3e-163 545.1 12.7 1.5e-163 544.9 8.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Response_reg PF00072.19 AIF82438.1 - 9.6e-14 51.3 0.1 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_24 PF13412.1 AIF82439.1 - 3.6e-07 29.4 2.0 7e-07 28.5 1.4 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF82439.1 - 0.0002 20.8 1.5 0.00048 19.5 1.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 AIF82439.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AsnC family HTH_28 PF13518.1 AIF82439.1 - 0.032 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 AIF82439.1 - 0.044 13.3 0.1 0.099 12.2 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.7 AIF82439.1 - 0.05 13.2 0.5 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 HTH domain TrmB PF01978.14 AIF82439.1 - 0.075 12.7 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.1 AIF82439.1 - 0.096 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Talin_middle PF09141.5 AIF82440.1 - 0.0055 16.3 4.3 0.0055 16.3 3.0 2.3 1 1 0 2 2 2 1 Talin, middle domain HisKA_3 PF07730.8 AIF82440.1 - 0.044 14.1 11.8 0.73 10.2 0.0 4.1 1 1 1 2 2 2 0 Histidine kinase DUF2359 PF10151.4 AIF82440.1 - 0.27 9.7 1.7 0.33 9.4 0.6 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) Fib_alpha PF08702.5 AIF82440.1 - 3.6 7.6 14.8 6.8 6.8 6.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.6 AIF82440.1 - 6.7 4.1 16.9 2.4 5.5 7.4 2.0 1 1 1 2 2 2 0 Prominin DUF2229 PF09989.4 AIF82440.1 - 8 5.8 14.9 1.2 8.5 5.6 2.2 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1056 PF06341.6 AIF82441.1 - 0.0071 16.3 2.3 0.0096 15.9 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1056) DUF4231 PF14015.1 AIF82441.1 - 0.056 13.4 0.4 0.068 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4282 PF14110.1 AIF82441.1 - 0.11 12.7 4.6 0.15 12.3 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF4131 PF13567.1 AIF82441.1 - 0.13 11.6 0.6 0.17 11.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4257 PF14074.1 AIF82441.1 - 0.37 10.4 2.1 0.46 10.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) DUF3554 PF12074.3 AIF82442.1 - 0.075 12.4 0.1 0.087 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) DUF4097 PF13349.1 AIF82442.1 - 0.094 12.2 0.3 0.099 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PepSY PF03413.14 AIF82444.1 - 7.3e-10 39.3 3.4 6.9e-06 26.6 0.5 2.4 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain PepSY_2 PF13670.1 AIF82444.1 - 0.034 14.0 2.2 1.1 9.1 0.0 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain DUF4292 PF14125.1 AIF82444.1 - 0.094 12.1 0.0 1 8.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4292) ACC_central PF08326.7 AIF82445.1 - 0.031 12.4 0.0 0.031 12.4 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF1470 PF07336.6 AIF82445.1 - 0.093 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) PaaA_PaaC PF05138.7 AIF82446.1 - 0.0041 16.1 0.2 0.0046 15.9 0.2 1.0 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein Apolipoprotein PF01442.13 AIF82446.1 - 0.013 14.9 0.2 0.022 14.2 0.2 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain GlutR_dimer PF00745.15 AIF82446.1 - 0.014 15.3 0.3 0.43 10.5 0.1 2.0 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Phasin PF05597.6 AIF82446.1 - 0.035 13.8 0.3 0.044 13.5 0.2 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AphA_like PF14557.1 AIF82446.1 - 0.058 12.9 0.1 0.058 12.9 0.0 1.0 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF3053 PF11254.3 AIF82446.1 - 0.073 12.3 0.3 0.081 12.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) HSCB_C PF07743.8 AIF82446.1 - 0.12 12.8 1.0 0.2 12.1 0.7 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain YqzH PF14164.1 AIF82446.1 - 0.12 12.2 0.1 0.25 11.2 0.0 1.6 1 1 1 2 2 2 0 YqzH-like protein DUF3618 PF12277.3 AIF82446.1 - 0.19 11.7 0.8 0.85 9.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3618) Response_reg PF00072.19 AIF82449.1 - 7.5e-19 67.7 0.5 1.3e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain PepSY PF03413.14 AIF82450.1 - 2.4e-06 28.1 0.4 4.1e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Pneumo_att_G PF05539.6 AIF82450.1 - 0.086 12.2 3.4 0.11 11.8 2.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF3750 PF12570.3 AIF82451.1 - 0.0022 18.2 0.1 0.0048 17.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3750) HATPase_c PF02518.21 AIF82452.1 - 1.4e-21 76.2 1.1 5.3e-21 74.4 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF82452.1 - 4.6e-12 45.7 0.1 4.6e-12 45.7 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AIF82452.1 - 0.012 15.2 0.2 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cache_3 PF14827.1 AIF82452.1 - 0.043 13.7 0.2 4.4 7.2 0.0 3.1 2 1 0 2 2 2 0 Sensory domain of two-component sensor kinase Sec34 PF04136.10 AIF82452.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Sec34-like family CpXC PF14353.1 AIF82454.1 - 0.028 14.3 0.9 0.11 12.4 0.6 1.9 1 1 1 2 2 2 0 CpXC protein Vps39_2 PF10367.4 AIF82454.1 - 0.039 14.1 0.4 0.052 13.7 0.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF2296 PF10058.4 AIF82454.1 - 0.56 10.0 2.5 3.2 7.5 1.9 2.0 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) p450 PF00067.17 AIF82455.1 - 1.2e-40 139.4 0.0 2.1e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 HicB PF05534.7 AIF82456.1 - 0.011 15.3 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 0 HicB family Nitro_FeMo-Co PF02579.12 AIF82457.1 - 0.034 14.2 0.0 0.034 14.2 0.0 1.0 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor AmoC PF04896.7 AIF82458.1 - 3.2e-16 59.1 4.4 3.8e-16 58.8 3.0 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C Fer4_7 PF12838.2 AIF82459.1 - 1.6e-09 37.9 27.3 3e-06 27.5 6.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.22 AIF82459.1 - 2.7e-09 36.2 13.0 2.7e-06 26.7 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AIF82459.1 - 2.4e-08 34.1 5.1 8.3e-08 32.3 3.5 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF82459.1 - 9.6e-08 31.9 22.8 3.8e-05 23.6 5.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIF82459.1 - 1.2e-07 31.2 10.0 0.0015 18.3 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 AIF82459.1 - 3.4e-07 29.8 12.8 0.002 17.9 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AIF82459.1 - 1.2e-06 28.1 9.0 1.7e-05 24.5 6.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 AIF82459.1 - 2.8e-06 27.7 5.9 0.0027 18.2 0.1 2.6 3 0 0 3 3 2 2 4Fe-4S single cluster domain Fer4_21 PF14697.1 AIF82459.1 - 9.7e-06 25.3 7.9 0.00081 19.1 5.5 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIF82459.1 - 1.4e-05 24.9 6.3 0.036 14.3 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AIF82459.1 - 2.1e-05 24.8 6.6 0.013 15.9 0.3 2.7 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_17 PF13534.1 AIF82459.1 - 2.5e-05 24.5 10.5 0.0014 18.9 4.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 AIF82459.1 - 2.7e-05 24.7 5.0 0.006 17.2 0.4 2.6 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 AIF82459.1 - 9e-05 22.8 8.6 0.0007 19.9 4.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.1 AIF82459.1 - 0.016 15.1 0.7 3.5 7.5 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 AIF82459.1 - 0.029 14.9 15.4 0.13 12.9 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain AsnC_trans_reg PF01037.16 AIF82460.1 - 8.2e-07 28.6 0.0 9.3e-07 28.4 0.0 1.0 1 0 0 1 1 1 1 AsnC family DZR PF12773.2 AIF82461.1 - 0.0014 18.3 10.6 0.0066 16.2 7.0 2.1 1 1 1 2 2 2 2 Double zinc ribbon Ribosomal_S27 PF01599.14 AIF82461.1 - 0.11 12.3 0.7 0.11 12.3 0.5 2.4 2 1 0 2 2 2 0 Ribosomal protein S27a DUF3133 PF11331.3 AIF82461.1 - 0.28 10.7 0.1 0.28 10.7 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3133) Ribosomal_L37e PF01907.14 AIF82461.1 - 0.6 9.9 17.0 3.2 7.6 4.3 2.9 1 1 2 3 3 3 0 Ribosomal protein L37e XPA_N PF01286.13 AIF82461.1 - 0.84 9.3 8.3 1.2 8.8 1.5 3.2 2 1 1 3 3 3 0 XPA protein N-terminal zf-C2H2 PF00096.21 AIF82461.1 - 1.6 9.2 0.1 1.6 9.2 0.0 3.8 3 1 0 3 3 3 0 Zinc finger, C2H2 type DnaJ_CXXCXGXG PF00684.14 AIF82461.1 - 5.8 7.0 13.9 1.5e+02 2.5 10.2 2.3 1 1 1 2 2 2 0 DnaJ central domain Polyketide_cyc2 PF10604.4 AIF82465.1 - 4.8e-11 42.9 0.0 5.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF82465.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HTH_24 PF13412.1 AIF82468.1 - 7.1e-05 22.1 0.9 0.00045 19.5 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Mga PF05043.8 AIF82468.1 - 0.0033 17.6 0.1 0.0085 16.3 0.1 1.7 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_11 PF08279.7 AIF82468.1 - 0.016 14.8 1.0 0.05 13.2 0.2 2.1 2 0 0 2 2 2 0 HTH domain HTH_psq PF05225.11 AIF82468.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_AsnC-type PF13404.1 AIF82468.1 - 0.036 13.6 0.1 0.09 12.3 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.1 AIF82468.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_20 PF12840.2 AIF82468.1 - 0.086 12.6 0.5 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.1 AIF82468.1 - 0.13 12.3 0.8 0.86 9.6 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain DUF1628 PF07790.6 AIF82470.1 - 0.0001 22.9 4.2 0.00015 22.4 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1628) Aa_trans PF01490.13 AIF82470.1 - 0.029 12.8 0.1 0.031 12.7 0.1 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein DUF3566 PF12089.3 AIF82470.1 - 0.053 13.5 0.3 0.058 13.3 0.2 1.0 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Na_H_Exchanger PF00999.16 AIF82471.1 - 4.1e-60 203.3 53.1 5.1e-60 203.0 36.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UPF0542 PF15086.1 AIF82471.1 - 0.098 12.3 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 zf-C2HC_2 PF13913.1 AIF82472.1 - 0.014 15.0 0.1 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Senescence PF06911.7 AIF82472.1 - 0.015 14.9 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Senescence-associated protein zf-C2H2_4 PF13894.1 AIF82472.1 - 0.093 13.1 2.9 1.3 9.5 1.0 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger 4HB_MCP_1 PF12729.2 AIF82473.1 - 5.1e-18 65.0 9.2 4.3e-10 39.2 0.8 2.6 2 0 0 2 2 2 2 Four helix bundle sensory module for signal transduction DUF835 PF05763.7 AIF82473.1 - 1.1e-09 37.9 0.1 2.6e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF835) TarH PF02203.10 AIF82473.1 - 0.056 13.2 0.4 0.056 13.2 0.3 3.0 3 0 0 3 3 3 0 Tar ligand binding domain homologue DUF4448 PF14610.1 AIF82473.1 - 0.12 11.8 1.7 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) RFXA_RFXANK_bdg PF15289.1 AIF82473.1 - 0.46 10.6 4.7 3.3 7.9 0.5 2.4 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain KaiC PF06745.8 AIF82474.1 - 7.4e-47 159.3 0.1 9e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AIF82474.1 - 8.9e-13 48.0 0.0 2.9e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 AIF82474.1 - 7e-08 31.6 0.0 1.5e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 AIF82474.1 - 0.00019 21.6 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIF82474.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain GvpD PF07088.6 AIF82474.1 - 0.0015 16.9 0.0 0.0081 14.5 0.0 1.9 1 1 0 1 1 1 1 GvpD gas vesicle protein AAA_18 PF13238.1 AIF82474.1 - 0.0038 17.5 0.0 0.0089 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIF82474.1 - 0.01 16.6 0.2 0.022 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AIF82474.1 - 0.021 14.9 0.3 0.065 13.4 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RecA PF00154.16 AIF82474.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.4 1 1 0 1 1 1 0 recA bacterial DNA recombination protein Fibrillarin PF01269.12 AIF82474.1 - 0.026 13.4 0.0 0.06 12.2 0.0 1.4 1 1 0 1 1 1 0 Fibrillarin NACHT PF05729.7 AIF82474.1 - 0.028 14.0 0.1 0.14 11.7 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 AIF82474.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 AIF82474.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 AIF82474.1 - 0.05 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 AIF82474.1 - 0.084 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.7 AIF82474.1 - 0.091 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 AIF82474.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Ras PF00071.17 AIF82474.1 - 0.14 11.5 0.0 2.4 7.5 0.0 2.2 1 1 1 2 2 2 0 Ras family FemAB PF02388.11 AIF82475.1 - 0.023 13.3 0.1 0.028 13.1 0.1 1.1 1 0 0 1 1 1 0 FemAB family RP-C_C PF11800.3 AIF82475.1 - 0.17 11.6 0.2 0.2 11.3 0.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region MEDS PF14417.1 AIF82476.1 - 7.3e-07 28.4 0.1 1.1e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain KaiC PF06745.8 AIF82476.1 - 0.0012 18.0 0.1 0.0019 17.3 0.1 1.3 1 0 0 1 1 1 1 KaiC DUF2269 PF10027.4 AIF82477.1 - 0.0069 16.1 4.7 0.0087 15.8 2.5 1.7 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) DUF4149 PF13664.1 AIF82477.1 - 0.95 9.5 11.0 0.03 14.3 1.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) zinc_ribbon_2 PF13240.1 AIF82479.1 - 8.5e-08 31.4 4.1 1.4e-07 30.7 2.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF82479.1 - 2.9e-07 29.4 2.6 5e-07 28.7 1.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AIF82479.1 - 5.8e-05 22.8 2.1 9.9e-05 22.0 1.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon ASFV_p27 PF06556.6 AIF82479.1 - 0.00034 20.5 0.4 0.0008 19.3 0.1 1.6 2 0 0 2 2 2 1 IAP-like protein p27 C-terminus UPF0547 PF10571.4 AIF82479.1 - 0.0034 17.0 3.4 0.0061 16.2 2.3 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Cript PF10235.4 AIF82479.1 - 0.0098 16.2 0.1 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT zf-DHHC PF01529.15 AIF82479.1 - 0.023 14.0 0.4 0.041 13.2 0.3 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2116 PF09889.4 AIF82479.1 - 0.045 13.5 1.4 0.085 12.6 1.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RRN7 PF11781.3 AIF82479.1 - 0.11 11.9 3.9 3.2 7.3 0.6 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Nudix_N_2 PF14803.1 AIF82479.1 - 0.65 9.7 5.2 6.1 6.6 0.7 2.4 2 0 0 2 2 2 0 Nudix N-terminal Prenyltransf PF01255.14 AIF82482.1 - 4.4e-76 254.9 0.7 5.2e-76 254.6 0.5 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Adenine_glyco PF03352.8 AIF82482.1 - 0.099 12.1 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase Asp_Glu_race PF01177.17 AIF82483.1 - 1.7e-28 99.9 0.0 2.4e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Polysacc_deac_1 PF01522.16 AIF82485.1 - 7.9e-10 38.4 0.0 1.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase TIG PF01833.19 AIF82485.1 - 0.055 13.4 0.3 0.14 12.1 0.2 1.7 1 0 0 1 1 1 0 IPT/TIG domain Spo0M PF07070.6 AIF82485.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Daxx PF03344.10 AIF82485.1 - 0.16 10.3 6.5 0.22 9.9 4.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 AIF82485.1 - 1.2 7.0 9.6 2.2 6.1 6.6 1.4 1 0 0 1 1 1 0 CDC45-like protein CCDC92 PF14916.1 AIF82486.1 - 0.16 11.5 1.3 0.35 10.4 0.9 1.7 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Snf7 PF03357.16 AIF82492.1 - 0.024 14.0 4.9 0.039 13.3 3.4 1.5 1 1 0 1 1 1 0 Snf7 CENP-F_leu_zip PF10473.4 AIF82492.1 - 0.3 10.9 2.2 0.56 10.0 1.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FtsX PF02687.16 AIF82493.1 - 0.046 13.4 4.0 0.058 13.1 2.8 1.1 1 0 0 1 1 1 0 FtsX-like permease family Acyl_transf_3 PF01757.17 AIF82493.1 - 0.077 11.8 2.3 0.075 11.8 1.6 1.0 1 0 0 1 1 1 0 Acyltransferase family UPF0154 PF03672.8 AIF82493.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Abhydrolase_9_N PF15420.1 AIF82493.1 - 0.4 10.4 2.2 0.41 10.3 1.6 1.0 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SPC12 PF06645.8 AIF82493.1 - 2.2 8.1 6.5 75 3.2 4.5 2.1 1 1 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TP_methylase PF00590.15 AIF82494.1 - 3.1e-45 154.4 1.6 3.3e-45 154.3 0.5 1.4 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.15 AIF82495.1 - 8.3e-48 162.8 0.2 9.9e-48 162.6 0.2 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.16 AIF82495.1 - 0.093 12.8 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Radical SAM superfamily HTH_OrfB_IS605 PF12323.3 AIF82496.1 - 3.6e-12 45.3 1.7 5.6e-12 44.7 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain OrfB_IS605 PF01385.14 AIF82496.1 - 5.8e-09 35.6 1.5 1.1e-08 34.8 1.1 1.4 1 1 0 1 1 1 1 Probable transposase OrfB_Zn_ribbon PF07282.6 AIF82497.1 - 9.9e-21 73.1 0.4 1.6e-20 72.4 0.1 1.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 AIF82497.1 - 0.00041 19.4 7.6 0.0032 16.6 1.7 2.2 2 1 1 3 3 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF82497.1 - 0.00087 18.7 0.6 0.84 9.2 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.2 AIF82497.1 - 0.0012 18.5 0.9 0.0021 17.8 0.3 1.5 1 1 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 AIF82497.1 - 0.0019 17.8 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 AIF82497.1 - 0.0023 17.2 1.0 0.024 13.9 0.8 2.1 1 1 1 2 2 2 1 TFIIB zinc-binding zf-NADH-PPase PF09297.6 AIF82497.1 - 0.017 14.5 3.3 0.055 12.9 2.3 1.9 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-ISL3 PF14690.1 AIF82497.1 - 0.018 15.0 3.5 1.5 8.9 0.0 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Auto_anti-p27 PF06677.7 AIF82497.1 - 0.02 14.6 1.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nudix_N_2 PF14803.1 AIF82497.1 - 0.021 14.5 6.2 0.11 12.1 1.7 3.0 2 1 0 2 2 2 0 Nudix N-terminal FYVE PF01363.16 AIF82497.1 - 0.025 14.4 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_1 PF14446.1 AIF82497.1 - 0.03 14.0 0.6 0.052 13.2 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Mss51 PF13824.1 AIF82497.1 - 0.039 13.8 3.1 1.1 9.1 0.1 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1936 PF09151.5 AIF82497.1 - 0.065 12.7 1.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) zinc_ribbon_4 PF13717.1 AIF82497.1 - 0.077 12.7 0.5 9.1 6.0 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Yippee-Mis18 PF03226.9 AIF82497.1 - 0.093 12.7 0.2 2.6 8.1 0.1 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_4 PF13894.1 AIF82497.1 - 0.094 13.0 0.7 5.4 7.5 0.0 2.6 1 1 1 2 2 2 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 AIF82497.1 - 0.097 12.2 0.5 12 5.6 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.1 AIF82497.1 - 0.25 11.3 1.1 2.7 7.9 0.0 2.6 2 1 1 3 3 3 0 CpXC protein Ribosomal_L37e PF01907.14 AIF82497.1 - 0.35 10.6 2.2 0.34 10.7 0.2 1.9 2 0 0 2 2 1 0 Ribosomal protein L37e DUF1610 PF07754.6 AIF82497.1 - 0.39 10.8 0.2 0.39 10.8 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Zn-ribbon_8 PF09723.5 AIF82497.1 - 0.53 10.2 4.3 4.1 7.4 3.0 2.2 1 1 0 1 1 1 0 Zinc ribbon domain UPF0547 PF10571.4 AIF82497.1 - 0.78 9.4 5.5 8.1 6.2 0.4 2.4 1 1 2 3 3 3 0 Uncharacterised protein family UPF0547 DnaJ PF00226.26 AIF82498.1 - 4.6e-25 87.1 1.0 8.5e-25 86.2 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Fer4_15 PF13459.1 AIF82498.1 - 2.2e-09 37.7 0.2 2.2e-09 37.7 0.2 2.4 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_13 PF13370.1 AIF82498.1 - 9.4e-07 29.1 0.2 9.4e-07 29.1 0.1 2.3 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_19 PF06902.6 AIF82498.1 - 2.6e-06 27.1 0.1 7.3e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Med6 PF04934.9 AIF82498.1 - 0.029 13.9 0.6 0.045 13.2 0.4 1.3 1 0 0 1 1 1 0 MED6 mediator sub complex component Fer4_7 PF12838.2 AIF82498.1 - 0.14 12.5 0.1 10 6.5 0.0 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain DUF1068 PF06364.7 AIF82498.1 - 0.15 11.6 1.6 0.25 10.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) AlaDh_PNT_C PF01262.16 AIF82498.1 - 1.1 8.7 4.9 2.2 7.8 3.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HAUS6_N PF14661.1 AIF82498.1 - 3.4 6.9 6.5 4.8 6.4 4.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HD_4 PF13328.1 AIF82500.1 - 8.1e-22 77.5 5.6 1.1e-21 77.2 3.9 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 AIF82500.1 - 6.4e-07 29.4 1.3 2.1e-06 27.7 0.3 2.2 2 1 0 2 2 2 1 HD domain SIMPL PF04402.9 AIF82501.1 - 2.6e-45 154.8 7.9 3.3e-45 154.5 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF1657 PF07870.6 AIF82501.1 - 0.032 13.8 0.9 0.055 13.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) M20_dimer PF07687.9 AIF82501.1 - 0.066 12.9 0.1 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase dimerisation domain Rotamase PF00639.16 AIF82503.1 - 3.2e-27 95.0 0.1 3.8e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AIF82503.1 - 6e-27 94.2 0.0 6.7e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 AIF82503.1 - 3.1e-11 43.9 0.0 3.5e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain PapD_C PF02753.12 AIF82503.1 - 0.09 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain PTS-HPr PF00381.14 AIF82505.1 - 0.0038 17.0 0.1 0.0096 15.7 0.1 1.7 1 0 0 1 1 1 1 PTS HPr component phosphorylation site Gln-synt_C PF00120.19 AIF82506.1 - 1.4e-88 296.3 0.0 1.8e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AIF82506.1 - 7.2e-24 83.1 0.0 1.9e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain AA_synth PF06684.6 AIF82506.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Amino acid synthesis TspO_MBR PF03073.10 AIF82508.1 - 0.009 15.5 2.0 0.011 15.2 1.4 1.0 1 0 0 1 1 1 1 TspO/MBR family IncA PF04156.9 AIF82508.1 - 0.064 12.8 2.1 0.069 12.7 1.4 1.2 1 0 0 1 1 1 0 IncA protein YlaH PF14036.1 AIF82508.1 - 2.2 8.4 5.5 3.3 7.8 3.8 1.4 1 1 0 1 1 1 0 YlaH-like protein PrgI PF12666.2 AIF82508.1 - 6.4 7.0 7.7 4.5 7.4 4.4 1.4 1 1 0 1 1 1 0 PrgI family protein RseC_MucC PF04246.7 AIF82508.1 - 9.4 5.8 6.5 39 3.8 4.5 1.8 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF1440 PF07274.7 AIF82509.1 - 0.016 15.1 4.1 0.021 14.7 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) YqhR PF11085.3 AIF82509.1 - 0.23 10.9 7.0 0.82 9.1 4.8 1.9 1 1 0 1 1 1 0 Conserved membrane protein YqhR TfoX_N PF04993.8 AIF82510.1 - 0.00073 19.3 0.0 0.00099 18.9 0.0 1.3 1 1 0 1 1 1 1 TfoX N-terminal domain DUF3251 PF11622.3 AIF82511.1 - 0.12 11.7 0.2 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) adh_short PF00106.20 AIF82512.1 - 3e-39 134.6 0.9 4.2e-39 134.1 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIF82512.1 - 1e-20 74.5 0.7 1.3e-20 74.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF82512.1 - 1.5e-14 54.1 0.4 2.2e-14 53.5 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AIF82512.1 - 6e-06 26.3 3.4 3.3e-05 23.9 2.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 AIF82512.1 - 0.00016 20.9 0.0 0.0002 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 AIF82512.1 - 0.00016 21.1 0.1 0.0024 17.3 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AIF82512.1 - 0.00034 20.3 4.0 0.001 18.8 2.8 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 AIF82512.1 - 0.0099 14.9 1.8 0.03 13.3 0.0 2.5 3 1 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.3 AIF82512.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 WAX2 C-terminal domain Pyr_redox_2 PF07992.9 AIF82514.1 - 1.1e-18 67.9 0.0 1.6e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AIF82514.1 - 3.8e-06 27.2 0.0 0.032 14.6 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AIF82514.1 - 5.8e-05 22.1 0.2 0.008 15.1 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIF82514.1 - 9.8e-05 22.3 0.1 0.00027 20.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AIF82514.1 - 0.002 16.6 0.0 0.075 11.4 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 AIF82514.1 - 0.0058 15.5 0.0 0.036 12.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 AIF82514.1 - 0.031 13.3 0.1 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 AIF82514.1 - 0.041 13.6 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AIF82514.1 - 0.043 13.8 0.1 0.65 10.0 0.1 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AIF82514.1 - 0.16 10.5 0.0 0.35 9.4 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase UPF0182 PF03699.8 AIF82515.1 - 0.014 13.3 2.2 0.017 13.0 1.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4153 PF13687.1 AIF82515.1 - 0.033 13.7 4.3 0.79 9.1 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) Fumarate_red_C PF02300.12 AIF82515.1 - 4.6 7.1 10.4 0.34 10.7 2.2 2.3 2 1 1 3 3 3 0 Fumarate reductase subunit C DctQ PF04290.7 AIF82515.1 - 6.7 6.4 14.2 13 5.5 2.0 2.5 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DNA_pol_B_thumb PF14791.1 AIF82516.1 - 3.9e-25 87.3 0.1 1e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 AIF82516.1 - 7.6e-17 61.2 9.4 2.6e-16 59.5 0.4 3.6 5 0 0 5 5 5 1 Helix-hairpin-helix domain HHH_5 PF14520.1 AIF82516.1 - 1.3e-10 41.3 11.6 8.6e-07 29.0 0.2 3.9 2 1 2 4 4 4 3 Helix-hairpin-helix domain PHP PF02811.14 AIF82516.1 - 8.9e-09 35.3 0.6 7e-08 32.4 0.2 2.3 2 1 0 2 2 2 1 PHP domain HHH PF00633.18 AIF82516.1 - 1.5e-07 30.7 2.3 0.0015 18.0 0.1 3.6 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_3 PF12836.2 AIF82516.1 - 0.00056 19.7 0.3 0.58 10.1 0.0 3.3 2 1 1 3 3 3 1 Helix-hairpin-helix motif HHH_2 PF12826.2 AIF82516.1 - 0.0031 17.3 0.0 0.58 10.0 0.0 3.0 1 1 1 2 2 2 1 Helix-hairpin-helix motif DNA_pol_B_palm PF14792.1 AIF82516.1 - 0.007 16.4 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm IMS_HHH PF11798.3 AIF82516.1 - 0.16 12.0 2.2 28 5.0 0.0 3.7 3 0 0 3 3 3 0 IMS family HHH motif Ribosomal_S13 PF00416.17 AIF82516.1 - 0.24 11.8 1.2 7.7 7.0 0.1 3.4 2 1 1 3 3 3 0 Ribosomal protein S13/S18 TFIIB PF00382.14 AIF82518.1 - 1.2e-26 92.2 1.3 8.1e-14 51.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AIF82518.1 - 2.1e-08 33.3 0.3 4.4e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.11 AIF82518.1 - 0.0022 17.2 0.3 0.11 11.8 0.0 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 zf-ribbon_3 PF13248.1 AIF82518.1 - 0.0093 15.1 0.3 0.016 14.4 0.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain HTH_AsnC-type PF13404.1 AIF82518.1 - 0.038 13.5 0.2 3.9 7.0 0.0 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Ribosomal_S27e PF01667.12 AIF82518.1 - 0.092 12.3 0.4 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 HTH_3 PF01381.17 AIF82518.1 - 0.12 12.1 0.3 5.2 6.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix Cyclin_C PF02984.14 AIF82518.1 - 0.14 12.0 0.1 10 6.0 0.0 2.6 2 1 0 2 2 2 0 Cyclin, C-terminal domain Rrf2 PF02082.15 AIF82518.1 - 0.27 11.3 1.2 11 6.2 0.0 3.1 3 1 0 3 3 3 0 Transcriptional regulator PTS_EIIC PF02378.13 AIF82519.1 - 0.0048 15.7 1.1 0.0048 15.7 0.8 1.0 1 0 0 1 1 1 1 Phosphotransferase system, EIIC TMEM125 PF15109.1 AIF82519.1 - 0.08 13.0 0.1 0.088 12.9 0.1 1.1 1 0 0 1 1 1 0 TMEM125 protein family RecX PF02631.11 AIF82520.1 - 0.039 14.1 0.3 0.06 13.5 0.2 1.4 1 0 0 1 1 1 0 RecX family DUF454 PF04304.8 AIF82520.1 - 0.069 13.1 0.1 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF454) dCMP_cyt_deam_1 PF00383.17 AIF82521.1 - 2.4e-24 84.8 1.0 3.1e-24 84.5 0.7 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 AIF82521.1 - 0.0011 18.5 0.1 0.0042 16.7 0.1 1.8 1 1 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.1 AIF82521.1 - 0.0018 17.8 0.1 0.0023 17.5 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.1 AIF82521.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Acetyltransf_1 PF00583.19 AIF82523.1 - 2.6e-13 49.7 0.1 5e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 AIF82523.1 - 1.8e-10 41.1 0.1 1e-09 38.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIF82523.1 - 5.2e-06 26.3 0.2 2.3e-05 24.2 0.0 2.2 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIF82523.1 - 2e-05 24.7 0.3 0.00015 21.8 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AIF82523.1 - 0.00017 21.7 0.0 0.00063 19.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIF82523.1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.1 AIF82523.1 - 0.0056 16.6 0.1 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Amb_V_allergen PF03913.8 AIF82523.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Amb V Allergen Acetyltransf_8 PF13523.1 AIF82523.1 - 0.015 15.1 0.2 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 AIF82524.1 - 1.4e-43 149.3 0.0 1.7e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIF82524.1 - 3.6e-20 72.1 0.0 8.2e-19 67.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIF82524.1 - 1.6e-19 70.3 0.0 9.7e-19 67.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 AIF82524.1 - 2.6e-05 23.8 0.1 4.7e-05 22.9 0.1 1.6 2 1 0 2 2 2 1 Putative esterase Thioesterase PF00975.15 AIF82524.1 - 0.00027 21.2 0.0 0.0003 21.0 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 AIF82524.1 - 0.00038 20.2 0.0 0.00083 19.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AIF82524.1 - 0.0024 17.4 0.1 0.0041 16.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 AIF82524.1 - 0.025 14.2 0.0 0.33 10.6 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 AIF82524.1 - 0.027 13.7 0.0 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 AIF82524.1 - 0.027 13.8 0.0 4 6.8 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2048 PF09752.4 AIF82524.1 - 0.028 13.2 0.1 0.063 12.1 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Ndr PF03096.9 AIF82524.1 - 0.044 12.2 0.0 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family Esterase_phd PF10503.4 AIF82524.1 - 0.12 11.5 0.4 1.7 7.8 0.1 2.1 1 1 0 2 2 2 0 Esterase PHB depolymerase Peptidase_M1 PF01433.15 AIF82525.1 - 5.1e-75 252.9 1.1 8.9e-75 252.1 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 HEAT_2 PF13646.1 AIF82525.1 - 1.5e-25 89.2 9.0 6.6e-11 42.3 0.0 3.8 1 1 3 4 4 4 4 HEAT repeats Peptidase_MA_2 PF13485.1 AIF82525.1 - 3.4e-16 59.4 1.1 7.8e-16 58.2 0.7 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_PBS PF03130.11 AIF82525.1 - 6.1e-11 41.7 6.1 0.023 15.1 0.4 6.0 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.17 AIF82525.1 - 6e-06 25.9 3.9 1.8 8.8 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 AIF82525.1 - 0.00023 21.5 5.0 0.18 12.3 0.1 3.7 2 1 1 3 3 3 3 HEAT-like repeat AMP-binding PF00501.23 AIF82526.1 - 1.6e-88 296.9 0.0 1.9e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AIF82526.1 - 1.2e-18 67.7 1.3 2.5e-18 66.7 0.9 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_20 PF12840.2 AIF82528.1 - 3e-15 55.7 0.1 5.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF82528.1 - 5.5e-14 51.5 0.0 7.9e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AIF82528.1 - 4.8e-06 25.8 0.0 7.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AIF82528.1 - 9.3e-06 25.2 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 AIF82528.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 AIF82528.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Phage_rep_org_N PF09681.5 AIF82528.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal phage replisome organiser (Phage_rep_org_N) MarR PF01047.17 AIF82528.1 - 0.0075 15.9 0.1 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.7 AIF82528.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 HTH domain Rrf2 PF02082.15 AIF82528.1 - 0.036 14.1 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Sigma70_r4 PF04545.11 AIF82528.1 - 0.042 13.1 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HSP90 PF00183.13 AIF82528.1 - 0.045 12.1 0.1 0.056 11.8 0.1 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF2513 PF10711.4 AIF82528.1 - 0.046 13.8 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_45 PF14947.1 AIF82528.1 - 0.052 13.3 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix Penicillinase_R PF03965.11 AIF82528.1 - 0.07 13.2 0.1 0.084 12.9 0.0 1.3 1 1 0 1 1 1 0 Penicillinase repressor HTH_IclR PF09339.5 AIF82528.1 - 0.083 12.4 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF4423 PF14394.1 AIF82528.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) AHSA1 PF08327.6 AIF82529.1 - 1.1e-76 254.8 11.8 1.7e-30 105.6 0.2 3.0 3 0 0 3 3 3 3 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 AIF82529.1 - 1e-18 67.8 14.9 6.3e-11 42.5 1.0 3.4 3 1 0 3 3 3 3 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF82529.1 - 5.5e-07 29.6 8.8 0.00042 20.3 0.2 4.0 3 2 0 3 3 3 3 Polyketide cyclase / dehydrase and lipid transport Halo_GVPC PF05465.8 AIF82529.1 - 0.31 11.0 3.6 7.8 6.5 0.2 2.6 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Trm56 PF01994.11 AIF82530.1 - 1e-51 173.7 0.3 1.4e-51 173.2 0.2 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 Lipoprot_C PF08794.5 AIF82530.1 - 0.048 13.5 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like MMR_HSR1 PF01926.18 AIF82531.1 - 5.9e-19 68.1 0.1 2.9e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 AIF82531.1 - 2.4e-11 43.6 0.7 6.3e-11 42.2 0.1 2.1 3 0 0 3 3 3 1 GTP-binding GTPase N-terminal FeoB_N PF02421.13 AIF82531.1 - 2.1e-08 33.6 0.0 6.3e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AIF82531.1 - 5.9e-06 25.8 0.1 0.0026 17.2 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AIF82531.1 - 0.0042 16.3 0.2 0.0042 16.3 0.1 2.4 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 AIF82531.1 - 0.0075 16.5 0.1 0.027 14.7 0.0 2.1 1 1 1 2 2 2 1 ABC transporter Dynamin_N PF00350.18 AIF82531.1 - 0.011 15.5 3.7 0.058 13.2 0.3 3.0 2 2 3 5 5 5 0 Dynamin family PduV-EutP PF10662.4 AIF82531.1 - 0.027 13.9 0.1 0.33 10.4 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 AIF82531.1 - 0.029 13.2 0.1 0.045 12.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 AIF82531.1 - 0.03 14.8 0.0 0.088 13.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 AIF82531.1 - 0.079 12.1 0.1 0.3 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 HTH_3 PF01381.17 AIF82532.1 - 1.3e-05 24.9 0.1 1.9e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 AIF82532.1 - 0.00032 20.8 0.0 0.00078 19.5 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.1 AIF82532.1 - 0.057 13.0 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.2 AIF82532.1 - 0.071 13.1 0.4 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Nudix_N_2 PF14803.1 AIF82532.1 - 0.099 12.3 0.6 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 Nudix N-terminal zf-dskA_traR PF01258.12 AIF82532.1 - 0.14 11.9 1.9 0.36 10.6 1.3 1.8 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger HTH_27 PF13463.1 AIF82533.1 - 0.00012 22.2 0.7 0.00041 20.6 0.2 2.0 2 1 0 2 2 2 1 Winged helix DNA-binding domain PhoU PF01895.14 AIF82534.1 - 6.8e-27 93.7 17.9 3.6e-18 65.7 2.7 2.8 3 0 0 3 3 3 2 PhoU domain Antitoxin-MazE PF04014.13 AIF82534.1 - 1.4e-09 37.4 0.0 3.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE HSBP1 PF06825.7 AIF82534.1 - 0.02 14.4 0.2 0.044 13.3 0.2 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 NAS PF03059.11 AIF82534.1 - 0.067 12.3 0.7 0.13 11.4 0.1 1.6 2 0 0 2 2 2 0 Nicotianamine synthase protein DUF2695 PF10905.3 AIF82534.1 - 0.083 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) PUA PF01472.15 AIF82535.1 - 7e-11 41.7 0.5 1.1e-10 41.1 0.3 1.3 1 0 0 1 1 1 1 PUA domain TGT_C2 PF14810.1 AIF82535.1 - 2.6e-09 36.8 0.0 4.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase NAC PF01849.13 AIF82536.1 - 9e-13 47.5 4.1 5.1e-11 41.9 1.4 2.1 2 0 0 2 2 2 2 NAC domain UBA PF00627.26 AIF82536.1 - 6.6e-05 22.6 0.1 0.00016 21.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 AIF82536.1 - 0.11 12.0 0.1 0.93 9.0 0.0 2.4 2 1 1 3 3 3 0 CUE domain Mitofilin PF09731.4 AIF82537.1 - 0.0019 16.9 9.1 0.0021 16.7 6.3 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Exonuc_VII_L PF02601.10 AIF82537.1 - 0.0022 17.2 4.0 0.0025 17.0 2.8 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit ATP-synt_B PF00430.13 AIF82537.1 - 0.0042 16.8 15.6 0.027 14.2 10.8 2.0 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) DUF826 PF05696.6 AIF82537.1 - 0.0051 16.9 3.3 0.028 14.5 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF826) Phage_connect_1 PF05135.8 AIF82537.1 - 0.013 15.6 0.9 0.044 13.9 0.6 1.8 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein Activator-TraM PF11657.3 AIF82537.1 - 0.014 14.8 7.7 0.019 14.4 5.3 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM Apolipoprotein PF01442.13 AIF82537.1 - 0.024 14.1 3.9 0.031 13.8 2.7 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Allexi_40kDa PF05549.6 AIF82537.1 - 0.028 13.7 1.8 0.033 13.4 1.3 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein CLTH PF10607.4 AIF82537.1 - 0.031 13.9 0.3 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Peptidase_M75 PF09375.5 AIF82537.1 - 0.031 13.5 2.0 0.038 13.3 1.4 1.1 1 0 0 1 1 1 0 Imelysin DUF4142 PF13628.1 AIF82537.1 - 0.06 13.3 8.9 0.1 12.6 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4142) Reo_sigmaC PF04582.7 AIF82537.1 - 0.066 12.3 4.3 0.085 12.0 3.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CsoSCA PF08936.5 AIF82537.1 - 0.087 11.1 2.0 0.12 10.6 1.0 1.3 1 1 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Phasin PF05597.6 AIF82537.1 - 0.087 12.5 8.0 1 9.1 1.2 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PhdYeFM_antitox PF02604.14 AIF82537.1 - 0.088 12.4 3.1 0.62 9.6 0.0 2.4 1 1 1 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system HrpE PF06188.7 AIF82537.1 - 0.09 12.5 4.1 0.12 12.1 2.9 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Muted PF14942.1 AIF82537.1 - 0.097 12.5 3.6 0.13 12.1 2.5 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF3781 PF12636.2 AIF82537.1 - 0.097 12.6 1.5 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) KfrA_N PF11740.3 AIF82537.1 - 0.098 13.1 8.9 0.5 10.8 4.6 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4456 PF14644.1 AIF82537.1 - 0.1 11.7 3.5 0.32 10.2 2.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4456) Phage_Mu_Gam PF07352.7 AIF82537.1 - 0.11 12.0 9.8 0.15 11.5 0.4 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF3552 PF12072.3 AIF82537.1 - 0.12 11.5 14.1 0.13 11.4 6.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CDC37_N PF03234.9 AIF82537.1 - 0.15 12.3 6.1 0.2 11.9 4.3 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding AAA_13 PF13166.1 AIF82537.1 - 0.16 10.4 7.1 0.17 10.2 4.9 1.1 1 0 0 1 1 1 0 AAA domain Hyccin PF09790.4 AIF82537.1 - 0.16 10.8 1.5 0.17 10.7 1.0 1.1 1 0 0 1 1 1 0 Hyccin DUF2894 PF11445.3 AIF82537.1 - 0.16 12.1 3.6 0.2 11.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Duffy_binding PF05424.6 AIF82537.1 - 0.17 11.7 3.4 0.23 11.2 2.3 1.2 1 0 0 1 1 1 0 Duffy binding domain Uds1 PF15456.1 AIF82537.1 - 0.19 11.7 7.7 1.4 8.9 0.1 3.0 1 1 1 2 2 2 0 Up-regulated During Septation COG5 PF10392.4 AIF82537.1 - 0.2 11.5 3.1 2.2 8.2 0.2 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 NRDE PF05742.7 AIF82537.1 - 0.22 10.7 1.9 0.29 10.3 1.2 1.3 1 1 0 1 1 1 0 NRDE protein DUF972 PF06156.8 AIF82537.1 - 0.24 11.7 6.4 0.64 10.3 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) VIT1 PF01988.14 AIF82537.1 - 0.24 10.8 4.7 0.31 10.4 3.3 1.3 1 0 0 1 1 1 0 VIT family Fzo_mitofusin PF04799.8 AIF82537.1 - 0.24 10.7 3.0 0.68 9.3 0.6 2.0 1 1 1 2 2 2 0 fzo-like conserved region LPP PF04728.8 AIF82537.1 - 0.25 11.1 1.8 3.5 7.5 1.3 2.4 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF1664 PF07889.7 AIF82537.1 - 0.27 11.0 6.6 0.13 12.0 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.8 AIF82537.1 - 0.33 11.3 8.9 0.64 10.4 4.5 2.3 1 1 2 3 3 2 0 Bacterial protein of unknown function (DUF883) PsbW PF07123.7 AIF82537.1 - 0.45 10.5 3.1 0.61 10.1 2.0 1.4 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Translin PF01997.11 AIF82537.1 - 0.46 10.0 4.7 9.9 5.6 2.0 2.1 1 1 1 2 2 2 0 Translin family DUF885 PF05960.6 AIF82537.1 - 0.47 9.5 4.2 0.52 9.3 2.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DivIVA PF05103.8 AIF82537.1 - 0.47 10.4 13.0 0.21 11.6 7.4 1.6 1 1 1 2 2 2 0 DivIVA protein Glu_syn_central PF04898.9 AIF82537.1 - 0.69 9.1 4.5 1.9 7.6 2.1 1.9 2 0 0 2 2 2 0 Glutamate synthase central domain FlaC_arch PF05377.6 AIF82537.1 - 0.78 9.6 6.8 0.58 10.0 1.4 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) vATP-synt_E PF01991.13 AIF82537.1 - 0.81 8.9 16.0 1.1 8.4 3.3 2.0 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit AAA_11 PF13086.1 AIF82537.1 - 1 8.8 7.0 1.5 8.3 4.9 1.3 1 1 0 1 1 1 0 AAA domain XhlA PF10779.4 AIF82537.1 - 1.1 9.2 10.2 6.5 6.7 0.1 2.5 1 1 1 2 2 2 0 Haemolysin XhlA COG2 PF06148.6 AIF82537.1 - 1.4 8.7 6.8 1.1 9.1 3.5 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HSCB_C PF07743.8 AIF82537.1 - 2 8.9 10.9 3 8.3 2.2 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain LUC7 PF03194.10 AIF82537.1 - 2.1 7.8 6.9 2.6 7.4 4.8 1.2 1 0 0 1 1 1 0 LUC7 N_terminus V-ATPase_G PF03179.10 AIF82537.1 - 2.2 8.6 14.4 5.6 7.3 7.5 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF2175 PF09943.4 AIF82537.1 - 4.2 7.4 9.1 2.4 8.2 3.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF4055 PF13264.1 AIF82537.1 - 5.3 7.1 7.2 1.5 8.8 3.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) DUF2203 PF09969.4 AIF82537.1 - 5.5 7.2 5.9 69 3.6 4.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF460 PF04312.8 AIF82538.1 - 0.00017 21.1 0.3 0.00031 20.2 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF460) UPF0081 PF03652.10 AIF82538.1 - 0.019 15.1 0.1 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0081) A2M_N PF01835.14 AIF82539.1 - 0.00024 21.2 0.6 0.0025 18.0 0.1 2.5 2 1 0 2 2 2 1 MG2 domain DUF3244 PF11589.3 AIF82539.1 - 0.00061 19.4 0.6 0.0054 16.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3244) FlgD_ig PF13860.1 AIF82539.1 - 0.015 14.9 2.8 0.024 14.3 0.4 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain CarboxypepD_reg PF13620.1 AIF82539.1 - 0.025 14.6 7.7 0.025 14.6 5.4 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain GRP PF07172.6 AIF82540.1 - 0.012 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family SH3BGR PF04908.10 AIF82540.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein HTH_45 PF14947.1 AIF82541.1 - 3.5e-06 26.7 0.0 5.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.1 AIF82541.1 - 0.0069 15.7 0.3 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Ta0938 PF11494.3 AIF82541.1 - 0.0093 16.0 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 Ta0938 Guanylate_cyc PF00211.15 AIF82542.1 - 1.1e-05 24.9 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Sgf11 PF08209.6 AIF82543.1 - 0.012 14.9 0.1 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) DUF2116 PF09889.4 AIF82543.1 - 0.014 15.1 0.2 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CbiA PF01656.18 AIF82544.1 - 8.1e-24 84.1 0.0 1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AIF82544.1 - 3.5e-16 59.5 0.5 6.7e-11 42.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain MipZ PF09140.6 AIF82544.1 - 4.4e-08 32.5 0.0 8.9e-06 24.9 0.0 2.2 1 1 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 AIF82544.1 - 4.6e-07 29.1 0.0 1.1e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 AIF82544.1 - 1.5e-05 24.2 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 AIF82544.1 - 3.2e-05 23.1 0.1 0.00028 20.0 0.0 2.3 2 1 0 2 2 2 1 VirC1 protein SRP54 PF00448.17 AIF82544.1 - 0.00016 21.1 0.1 0.0024 17.3 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 AIF82544.1 - 0.0012 19.6 0.5 0.0042 17.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AIF82544.1 - 0.0015 18.2 0.0 0.0077 15.9 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AIF82544.1 - 0.0023 17.3 0.1 0.077 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 AIF82544.1 - 0.0026 17.1 0.2 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 AIF82544.1 - 0.0082 16.1 0.3 0.51 10.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 AIF82544.1 - 0.0085 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_19 PF13245.1 AIF82544.1 - 0.024 14.3 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 AIF82544.1 - 0.032 14.5 0.3 0.17 12.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain YhjQ PF06564.7 AIF82544.1 - 0.034 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 YhjQ protein Abhydrolase_5 PF12695.2 AIF82544.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LpxK PF02606.9 AIF82544.1 - 0.079 11.9 0.1 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase ATP_bind_1 PF03029.12 AIF82544.1 - 0.081 12.4 0.2 0.9 9.0 0.2 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 AIF82544.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PCYCGC PF13798.1 AIF82544.1 - 0.12 12.0 0.1 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif IstB_IS21 PF01695.12 AIF82544.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Fic PF02661.13 AIF82545.1 - 6.7e-25 87.6 0.0 2e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 Fic/DOC family Methyltransf_18 PF12847.2 AIF82549.1 - 5.3e-13 49.5 0.0 7.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 AIF82549.1 - 2.1e-10 40.4 0.0 2.2e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 AIF82549.1 - 3.6e-09 36.9 0.0 5.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82549.1 - 2.1e-08 34.0 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF82549.1 - 2.8e-08 34.1 0.0 4.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF82549.1 - 3.4e-08 33.2 0.0 4.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 AIF82549.1 - 1.3e-06 27.7 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 AIF82549.1 - 5e-06 26.8 0.0 7.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0146 PF03686.8 AIF82549.1 - 7e-05 22.6 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) MTS PF05175.9 AIF82549.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 AIF82549.1 - 0.0024 17.0 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 AIF82549.1 - 0.0085 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 AIF82549.1 - 0.06 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.6 AIF82549.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CheR PF01739.13 AIF82549.1 - 0.15 11.3 0.1 0.32 10.2 0.0 1.6 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 AIF82549.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HATPase_c PF02518.21 AIF82550.1 - 2.3e-26 91.6 0.3 8e-26 89.9 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF82550.1 - 4.1e-11 42.7 1.2 1.5e-09 37.6 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Guanylate_cyc PF00211.15 AIF82551.1 - 2.1e-14 53.2 0.0 2.3e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1670 PF07900.6 AIF82551.1 - 0.0076 15.4 0.2 1 8.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1670) PPK2 PF03976.9 AIF82552.1 - 4e-63 212.7 0.8 3.2e-32 111.6 1.1 2.0 2 0 0 2 2 2 2 Polyphosphate kinase 2 (PPK2) Thymidylate_kin PF02223.12 AIF82552.1 - 0.03 13.6 0.0 0.24 10.7 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Trehalase PF01204.13 AIF82552.1 - 0.033 12.8 0.6 0.047 12.3 0.4 1.1 1 0 0 1 1 1 0 Trehalase AAA_18 PF13238.1 AIF82552.1 - 0.038 14.2 1.3 0.084 13.1 0.7 1.9 1 1 0 1 1 1 0 AAA domain PNPase_C PF12111.3 AIF82552.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal PIN PF01850.16 AIF82553.1 - 2.9e-14 53.4 0.0 3.2e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 PIN domain adh_short_C2 PF13561.1 AIF82553.1 - 0.0075 16.0 0.0 0.0088 15.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L31e PF01198.14 AIF82553.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L31e NO_synthase PF02898.10 AIF82553.1 - 0.15 10.6 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain DUF217 PF02697.9 AIF82554.1 - 2.3e-14 53.3 0.1 2.7e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1753 Tail_P2_I PF09684.5 AIF82554.1 - 0.096 12.2 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) Amino_oxidase PF01593.19 AIF82556.1 - 6.8e-17 61.6 0.0 1.6e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AIF82556.1 - 1.6e-15 56.8 1.5 5.5e-15 55.1 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AIF82556.1 - 1.6e-13 50.3 2.3 4.6e-13 48.8 1.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 AIF82556.1 - 4.5e-12 45.5 0.1 9.2e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 AIF82556.1 - 1e-08 34.4 1.6 1.3e-08 34.1 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 AIF82556.1 - 1.7e-08 34.0 0.6 1.3e-07 31.0 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AIF82556.1 - 1.9e-08 33.2 0.9 0.00029 19.4 0.7 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 AIF82556.1 - 7.6e-08 32.4 0.3 8.5e-05 22.5 0.3 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AIF82556.1 - 7.1e-07 28.5 0.4 1.1e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 AIF82556.1 - 1.2e-06 28.7 0.5 5.3e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AIF82556.1 - 7.9e-05 21.6 1.6 0.00024 20.1 0.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 AIF82556.1 - 0.00017 21.8 0.8 0.0075 16.6 0.2 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIF82556.1 - 0.0075 15.2 0.7 0.094 11.6 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 AIF82556.1 - 0.0075 16.0 0.4 0.9 9.2 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 AIF82556.1 - 0.018 14.6 1.3 0.039 13.5 0.9 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 AIF82556.1 - 0.025 14.2 0.3 0.059 13.0 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Strep_67kDa_ant PF06100.6 AIF82556.1 - 0.028 12.7 0.1 0.028 12.7 0.1 1.7 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GDI PF00996.13 AIF82556.1 - 0.03 12.6 0.0 0.15 10.3 0.0 1.8 1 1 1 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.9 AIF82556.1 - 0.05 12.2 1.0 0.082 11.5 0.7 1.3 1 0 0 1 1 1 0 Tryptophan halogenase BSP_II PF05432.6 AIF82556.1 - 0.059 12.6 3.8 0.096 11.9 2.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Shikimate_DH PF01488.15 AIF82556.1 - 0.068 13.2 0.3 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 AIF82556.1 - 0.089 12.6 0.6 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 AIF82556.1 - 0.1 11.9 0.2 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TetR_N PF00440.18 AIF82557.1 - 4e-15 55.1 0.4 1.1e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.1 AIF82557.1 - 0.0021 18.0 0.0 0.37 10.8 0.0 2.4 1 1 0 1 1 1 1 Bacterial transcriptional repressor WHG PF13305.1 AIF82557.1 - 0.024 15.2 0.0 1.6 9.3 0.0 3.0 3 1 0 3 3 3 0 WHG domain UPF0150 PF03681.10 AIF82557.1 - 0.045 13.3 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) CBM_11 PF03425.8 AIF82558.1 - 0.028 14.0 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) DUF4360 PF14273.1 AIF82560.1 - 0.074 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) PepSY_TM_3 PF13706.1 AIF82560.1 - 0.35 10.3 1.3 0.57 9.6 0.9 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix PD40 PF07676.7 AIF82562.1 - 1.1e-36 123.9 19.1 1.1e-09 37.7 0.2 5.9 5 0 0 5 5 5 5 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 AIF82562.1 - 2.7e-09 36.1 5.4 0.00019 20.1 0.1 4.2 2 1 3 5 5 5 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF444 PF04285.7 AIF82562.1 - 0.21 10.1 0.3 0.37 9.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) GAS PF13851.1 AIF82564.1 - 6.6 5.8 34.0 0.35 10.0 7.2 3.3 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2656 PF10847.3 AIF82565.1 - 0.064 13.1 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) DUF4157 PF13699.1 AIF82566.1 - 1.7e-32 111.3 0.2 5.1e-32 109.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4157) RecX PF02631.11 AIF82566.1 - 0.019 15.1 0.8 0.65 10.2 0.1 2.9 2 0 0 2 2 2 0 RecX family DUF4157 PF13699.1 AIF82567.1 - 8.2e-22 77.1 1.2 2.1e-21 75.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4157) DUF4156 PF13698.1 AIF82567.1 - 0.071 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) ParBc PF02195.13 AIF82568.1 - 6.9e-21 74.1 0.1 1.8e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain KorB PF08535.5 AIF82568.1 - 9.1e-05 22.5 0.1 0.0002 21.4 0.0 1.7 1 1 0 1 1 1 1 KorB domain DUF1861 PF08950.5 AIF82568.1 - 0.04 12.7 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1861) zf-CW PF07496.10 AIF82568.1 - 0.12 12.0 0.7 0.22 11.2 0.5 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger DUF4280 PF14107.1 AIF82569.1 - 0.00017 21.8 1.3 0.00035 20.8 0.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4280) PAAR_motif PF05488.8 AIF82569.1 - 0.054 13.4 1.6 0.12 12.4 1.1 1.7 1 1 0 1 1 1 0 PAAR motif GPW_gp25 PF04965.9 AIF82570.1 - 4e-12 45.5 0.1 4.8e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Gp_dh_N PF00044.19 AIF82570.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Baseplate_J PF04865.9 AIF82571.1 - 4.8e-07 29.3 0.0 1.4e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Baseplate J-like protein DUF968 PF06147.6 AIF82572.1 - 0.19 11.5 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF968) Big_4 PF07532.6 AIF82575.1 - 0.051 13.0 1.2 4.3 6.9 0.0 2.9 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 4) Phage_sheath_1 PF04984.9 AIF82576.1 - 3.2e-52 177.5 0.0 4.1e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Phage tail sheath protein Arb2 PF09757.4 AIF82576.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Arb2 domain Phage_T4_gp19 PF06841.7 AIF82577.1 - 2.7e-38 130.6 0.0 3.1e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 T4-like virus tail tube protein gp19 zf-ribbon_3 PF13248.1 AIF82578.1 - 0.2 10.9 2.0 3.1 7.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.6 AIF82578.1 - 0.41 9.9 2.6 1.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 AIF82578.1 - 0.73 9.5 4.4 1 9.1 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF4255 PF14065.1 AIF82580.1 - 1.2e-30 106.3 0.1 2.6e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4255) AAA PF00004.24 AIF82581.1 - 7.7e-25 87.6 0.0 2.4e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AIF82581.1 - 0.0031 17.4 0.0 0.0088 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIF82581.1 - 0.0055 16.8 0.2 1.1 9.3 0.0 3.2 3 1 1 4 4 4 1 AAA domain TIP49 PF06068.8 AIF82581.1 - 0.041 12.6 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 AIF82581.1 - 0.16 12.8 0.0 0.49 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Phage_base_V PF04717.7 AIF82583.1 - 9.7e-14 51.0 0.0 5e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Phage-related baseplate assembly protein DUF4098 PF13345.1 AIF82583.1 - 0.009 15.9 3.0 0.021 14.7 2.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4098) Phage_tail_X PF05489.7 AIF82585.1 - 0.043 13.3 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X HTH_20 PF12840.2 AIF82589.1 - 2e-05 24.2 0.8 4.4e-05 23.1 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF82589.1 - 0.0077 15.8 0.3 0.012 15.2 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF82589.1 - 0.037 13.6 0.2 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_45 PF14947.1 AIF82589.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DUF3689 PF12463.3 AIF82590.1 - 0.022 13.5 0.3 0.046 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) Spt5_N PF11942.3 AIF82590.1 - 2.6 8.6 12.5 2.5 8.7 1.8 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal YfhO PF09586.5 AIF82590.1 - 7.8 4.3 9.1 9.9 4.0 6.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Robl_LC7 PF03259.12 AIF82591.1 - 0.0082 15.6 0.1 0.011 15.3 0.0 1.2 1 1 0 1 1 1 1 Roadblock/LC7 domain REJ PF02010.10 AIF82591.1 - 0.13 10.5 0.5 0.14 10.4 0.4 1.0 1 0 0 1 1 1 0 REJ domain DUF1015 PF06245.6 AIF82594.1 - 0.15 10.5 0.1 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) Ecm33 PF12454.3 AIF82595.1 - 5.6 6.9 6.2 13 5.7 0.1 2.2 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Trypsin_2 PF13365.1 AIF82596.1 - 1.2e-15 57.5 0.0 8.5e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 AIF82596.1 - 9.5e-08 31.8 0.0 6.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Trypsin Fis1_TPR_C PF14853.1 AIF82596.1 - 0.0081 16.0 0.3 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Peptidase_S7 PF00949.16 AIF82596.1 - 0.031 13.6 0.2 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S29 PF02907.10 AIF82596.1 - 0.051 13.1 0.1 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease TPR_6 PF13174.1 AIF82596.1 - 0.1 13.1 0.7 0.31 11.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S46 PF10459.4 AIF82596.1 - 0.13 10.6 0.2 5.8 5.1 0.3 2.1 2 0 0 2 2 2 0 Peptidase S46 TFIIS_M PF07500.9 AIF82598.1 - 0.019 15.0 0.5 0.021 14.8 0.3 1.2 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain ATP-synt_10 PF05176.9 AIF82598.1 - 0.08 12.1 1.0 0.079 12.2 0.7 1.0 1 0 0 1 1 1 0 ATP10 protein DUF3364 PF11844.3 AIF82598.1 - 0.091 12.8 0.6 12 6.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3364) TFIIB PF00382.14 AIF82602.1 - 1.2e-30 105.1 4.6 4e-16 58.5 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AIF82602.1 - 1.1e-07 31.0 0.1 2.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_24 PF13412.1 AIF82602.1 - 3.8e-05 22.9 0.0 0.00033 19.9 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AIF82602.1 - 4.2e-05 23.1 0.0 0.00046 19.7 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_AsnC-type PF13404.1 AIF82602.1 - 0.00011 21.6 0.0 0.00072 19.0 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Cyclin_N PF00134.18 AIF82602.1 - 0.00036 20.0 0.2 0.57 9.7 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain Sigma70_r4 PF04545.11 AIF82602.1 - 0.001 18.3 0.0 0.039 13.2 0.0 2.6 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_23 PF13384.1 AIF82602.1 - 0.018 14.6 0.0 0.083 12.5 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Mga PF08280.6 AIF82602.1 - 0.019 14.7 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4_2 PF08281.7 AIF82602.1 - 0.019 14.4 0.2 0.46 9.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.17 AIF82602.1 - 0.023 14.5 0.0 0.21 11.4 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix HrcA_DNA-bdg PF03444.10 AIF82602.1 - 0.046 13.1 0.1 1 8.8 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TetR_N PF00440.18 AIF82602.1 - 0.07 12.7 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HARE-HTH PF05066.8 AIF82602.1 - 0.11 12.8 0.3 16 5.9 0.0 2.5 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Rrf2 PF02082.15 AIF82602.1 - 0.12 12.5 0.1 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator zinc_ribbon_5 PF13719.1 AIF82603.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AIF82603.1 - 0.074 13.0 0.3 0.63 10.0 0.2 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 AIF82603.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 AIF82603.1 - 0.18 11.7 2.5 0.65 9.9 0.0 2.5 2 1 1 3 3 3 0 C2H2-type zinc finger MMR_HSR1 PF01926.18 AIF82604.1 - 5.8e-17 61.7 0.4 2e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 AIF82604.1 - 1.2e-13 51.0 0.1 5.9e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal FeoB_N PF02421.13 AIF82604.1 - 3e-07 29.8 0.5 7.2e-07 28.6 0.0 1.9 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AIF82604.1 - 3e-05 23.5 0.2 0.00072 19.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AIF82604.1 - 0.00021 20.5 0.1 0.00038 19.7 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 AIF82604.1 - 0.00039 19.6 0.1 0.0013 17.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AIF82604.1 - 0.00053 20.2 0.4 0.0024 18.1 0.0 2.3 2 1 0 2 2 2 1 ABC transporter cobW PF02492.14 AIF82604.1 - 0.0015 17.9 2.3 0.92 8.9 0.0 2.8 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 AIF82604.1 - 0.0016 17.9 0.3 0.032 13.7 0.2 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 AIF82604.1 - 0.0029 17.4 1.4 0.0099 15.7 0.7 2.1 1 1 1 2 2 2 1 Dynamin family AAA_33 PF13671.1 AIF82604.1 - 0.012 15.4 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AIF82604.1 - 0.017 14.7 0.6 0.12 12.1 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 AIF82604.1 - 0.033 13.7 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 AIF82604.1 - 0.036 14.5 0.4 0.21 12.1 0.1 2.5 2 1 0 2 2 2 0 Miro-like protein T2SE PF00437.15 AIF82604.1 - 0.041 12.7 0.1 0.075 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 AIF82604.1 - 0.22 11.8 2.4 15 5.9 0.4 2.7 2 1 0 2 2 2 0 AAA domain eIF-1a PF01176.14 AIF82605.1 - 1.1e-21 76.0 1.2 1.3e-21 75.7 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.14 AIF82605.1 - 0.011 15.3 1.7 0.037 13.7 0.4 2.1 2 1 0 2 2 2 0 Myosin N-terminal SH3-like domain DUF1314 PF07013.6 AIF82605.1 - 0.056 12.8 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Cpn60_TCP1 PF00118.19 AIF82606.1 - 2.2e-162 541.0 12.0 2.6e-162 540.8 8.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1884 PF08967.5 AIF82606.1 - 0.017 15.1 2.0 3.4 7.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1884) AAA PF00004.24 AIF82607.1 - 9.2e-98 323.5 0.0 9.1e-50 168.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AIF82607.1 - 1.3e-24 85.9 0.1 4.2e-24 84.3 0.1 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AIF82607.1 - 3e-15 55.9 0.0 1.8e-09 37.0 0.0 2.9 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AIF82607.1 - 4e-15 56.1 0.0 1.3e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AIF82607.1 - 6.6e-14 52.3 0.0 8.1e-06 25.9 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 AIF82607.1 - 1.3e-13 51.2 0.3 5.8e-05 23.2 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AIF82607.1 - 7.3e-13 48.4 0.6 1.1e-06 28.4 0.0 3.8 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AIF82607.1 - 2.4e-12 47.7 0.1 6.5e-06 26.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AIF82607.1 - 2.4e-11 43.6 0.0 5.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AIF82607.1 - 2.5e-10 39.7 0.0 3.6e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 AIF82607.1 - 5.6e-10 38.5 0.1 0.00013 20.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 AIF82607.1 - 3.2e-09 36.8 0.0 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AIF82607.1 - 5.5e-09 35.6 0.1 0.0035 16.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 AIF82607.1 - 1.7e-08 34.4 0.0 0.00062 19.5 0.0 3.4 2 1 1 3 3 3 2 Archaeal ATPase Sigma54_activat PF00158.21 AIF82607.1 - 1.1e-07 31.4 0.1 0.038 13.4 0.1 3.8 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_25 PF13481.1 AIF82607.1 - 1.3e-07 31.1 5.6 0.45 9.8 0.1 4.3 2 2 1 4 4 4 2 AAA domain RNA_helicase PF00910.17 AIF82607.1 - 1.6e-07 31.4 0.0 0.0097 16.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 AIF82607.1 - 2.8e-07 30.8 0.0 0.0076 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 AIF82607.1 - 7.4e-07 28.7 0.0 2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_28 PF13521.1 AIF82607.1 - 7.6e-07 29.2 0.0 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 AIF82607.1 - 1.6e-06 27.8 0.1 0.024 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AIF82607.1 - 2e-06 27.4 4.1 0.004 16.8 0.1 3.1 4 0 0 4 4 2 2 Part of AAA domain Bac_DnaA PF00308.13 AIF82607.1 - 2.1e-06 27.5 0.0 0.028 14.0 0.0 2.9 2 1 0 2 2 2 2 Bacterial dnaA protein NACHT PF05729.7 AIF82607.1 - 3.2e-06 26.9 0.0 0.52 9.9 0.0 3.9 3 1 1 4 4 4 2 NACHT domain KaiC PF06745.8 AIF82607.1 - 4e-06 26.1 1.2 0.13 11.3 0.0 3.6 3 1 1 4 4 3 2 KaiC Mg_chelatase PF01078.16 AIF82607.1 - 4.4e-06 26.0 0.3 0.031 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI PhoH PF02562.11 AIF82607.1 - 7e-06 25.4 0.2 0.098 11.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.8 AIF82607.1 - 2e-05 23.6 0.0 0.037 12.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 AIF82607.1 - 3.4e-05 23.9 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 AIF82607.1 - 6.5e-05 23.2 0.0 0.56 10.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter NB-ARC PF00931.17 AIF82607.1 - 7.9e-05 21.6 0.0 0.079 11.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.10 AIF82607.1 - 0.00014 21.5 1.5 2.5 7.7 0.0 4.4 3 1 1 4 4 4 1 NTPase AAA_3 PF07726.6 AIF82607.1 - 0.00038 20.0 0.0 0.089 12.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.16 AIF82607.1 - 0.00044 19.7 0.1 1.8 7.9 0.0 3.7 2 1 1 3 3 3 1 Guanylate kinase Parvo_NS1 PF01057.12 AIF82607.1 - 0.00061 18.7 0.1 0.27 10.0 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 T2SE PF00437.15 AIF82607.1 - 0.0011 17.9 0.0 1.4 7.7 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF2075 PF09848.4 AIF82607.1 - 0.0012 17.8 0.0 0.43 9.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 AIF82607.1 - 0.0015 18.1 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 AIF82607.1 - 0.0017 18.2 0.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase AAA_30 PF13604.1 AIF82607.1 - 0.0034 17.0 0.1 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 AIF82607.1 - 0.0047 15.9 0.0 1.6 7.6 0.0 3.0 2 1 1 3 3 3 1 KAP family P-loop domain ATP-synt_ab PF00006.20 AIF82607.1 - 0.0083 15.6 0.1 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 AIF82607.1 - 0.011 15.3 0.0 3.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.10 AIF82607.1 - 0.02 14.7 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 AIF82607.1 - 0.036 13.5 0.0 7.4 6.0 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 AIF82607.1 - 0.055 12.6 0.0 3.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IPT PF01745.11 AIF82607.1 - 0.056 12.6 0.1 6.8 5.7 0.0 2.6 2 0 0 2 2 2 0 Isopentenyl transferase AAA_29 PF13555.1 AIF82607.1 - 0.06 12.8 0.1 14 5.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.1 AIF82607.1 - 0.064 12.8 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 AIF82607.1 - 0.11 11.3 0.0 13 4.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 AIF82607.1 - 0.13 11.7 2.2 24 4.2 0.2 3.9 2 2 1 3 3 3 0 AAA-like domain SRPRB PF09439.5 AIF82607.1 - 0.13 11.4 0.0 15 4.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 AIF82607.1 - 0.15 12.3 0.7 18 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF927 PF06048.6 AIF82607.1 - 0.17 11.0 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF927) AAA_21 PF13304.1 AIF82607.1 - 0.19 11.6 4.3 3.9 7.3 0.0 3.2 2 2 0 4 4 3 0 AAA domain AFG1_ATPase PF03969.11 AIF82607.1 - 0.2 10.4 0.0 12 4.6 0.0 2.6 2 0 0 2 2 2 0 AFG1-like ATPase DAP3 PF10236.4 AIF82607.1 - 0.22 10.4 0.0 13 4.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Fimbrial_CS1 PF04449.7 AIF82608.1 - 0.022 14.7 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 CS1 type fimbrial major subunit Usp PF00582.21 AIF82609.1 - 1.2e-31 109.7 0.1 1.8e-31 109.1 0.1 1.3 1 1 0 1 1 1 1 Universal stress protein family GARS_N PF02844.10 AIF82609.1 - 0.097 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain TMF_DNA_bd PF12329.3 AIF82611.1 - 0.0012 18.6 7.1 0.0012 18.6 4.0 1.6 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 AIF82611.1 - 0.0055 16.3 2.4 0.0056 16.3 1.6 1.2 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 phiKZ_IP PF12699.2 AIF82611.1 - 0.013 14.4 0.6 0.015 14.2 0.4 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins DUF1319 PF07028.6 AIF82611.1 - 0.016 15.3 2.5 0.018 15.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) bZIP_1 PF00170.16 AIF82611.1 - 0.016 15.1 4.8 0.018 14.9 3.0 1.4 1 1 1 2 2 2 0 bZIP transcription factor Blo-t-5 PF11642.3 AIF82611.1 - 0.023 14.4 0.8 0.023 14.4 0.5 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 Ax_dynein_light PF10211.4 AIF82611.1 - 0.039 13.7 1.1 0.04 13.7 0.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Laminin_II PF06009.7 AIF82611.1 - 0.068 12.9 1.6 0.077 12.7 1.1 1.1 1 0 0 1 1 1 0 Laminin Domain II Snapin_Pallidin PF14712.1 AIF82611.1 - 0.072 13.3 1.8 0.095 13.0 1.1 1.3 1 1 0 1 1 1 0 Snapin/Pallidin APG6 PF04111.7 AIF82611.1 - 0.079 11.9 3.7 0.087 11.8 2.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2802 PF10975.3 AIF82611.1 - 0.1 12.3 1.5 0.16 11.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Prefoldin PF02996.12 AIF82611.1 - 0.12 12.0 2.7 0.17 11.5 1.9 1.2 1 0 0 1 1 1 0 Prefoldin subunit SlyX PF04102.7 AIF82611.1 - 0.2 12.0 2.6 0.32 11.3 1.8 1.4 1 0 0 1 1 1 0 SlyX Latarcin PF10279.4 AIF82611.1 - 0.22 11.7 2.3 0.23 11.6 1.6 1.2 1 0 0 1 1 1 0 Latarcin precursor DivIC PF04977.10 AIF82611.1 - 0.3 10.5 2.3 0.38 10.2 1.6 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 AIF82611.1 - 0.37 11.1 2.6 0.64 10.3 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 AIF82611.1 - 0.43 10.9 5.6 0.52 10.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) XhlA PF10779.4 AIF82611.1 - 0.97 9.3 6.0 1.4 8.8 4.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA IncA PF04156.9 AIF82611.1 - 1 8.9 4.5 1.1 8.8 3.1 1.1 1 0 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 AIF82611.1 - 6.1 6.9 6.2 18 5.4 0.2 2.7 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat EIF_2_alpha PF07541.7 AIF82612.1 - 1.3e-19 70.0 0.7 2.6e-19 69.0 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AIF82612.1 - 1.1e-09 38.2 0.1 2.9e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 AIF82612.1 - 0.077 12.9 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 MEDS PF14417.1 AIF82613.1 - 1.6e-10 40.3 0.0 2.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain KaiC PF06745.8 AIF82613.1 - 0.0062 15.6 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 KaiC MEDS PF14417.1 AIF82614.1 - 1.1e-07 31.1 0.0 2.8e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain NMO PF03060.10 AIF82615.1 - 2.7e-76 256.8 2.0 1.8e-74 250.8 1.4 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 AIF82615.1 - 2.6e-11 42.9 1.9 4.2e-11 42.2 1.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 AIF82615.1 - 2.8e-07 29.7 5.3 4.9e-05 22.3 1.4 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 AIF82615.1 - 1.4e-06 27.4 0.1 3e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TIM-br_sig_trns PF09370.5 AIF82615.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 TIM-barrel signal transduction protein DHO_dh PF01180.16 AIF82615.1 - 0.0033 16.4 0.3 0.006 15.5 0.2 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 AIF82615.1 - 0.0043 16.3 0.9 0.0091 15.2 0.6 1.4 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF561 PF04481.7 AIF82615.1 - 0.0065 15.4 1.4 0.092 11.6 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF561) ThiG PF05690.9 AIF82615.1 - 0.0066 15.5 0.6 0.01 14.9 0.4 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 AIF82615.1 - 0.027 13.4 1.6 0.053 12.4 1.1 1.6 1 1 0 1 1 1 0 Conserved region in glutamate synthase Abhydrolase_6 PF12697.2 AIF82616.1 - 1.4e-25 90.5 0.0 1.7e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIF82616.1 - 6.7e-12 45.3 0.0 1.4e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIF82616.1 - 2.9e-08 33.5 0.0 6.9e-08 32.3 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 AIF82616.1 - 0.056 12.8 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.5 AIF82616.1 - 0.059 13.2 0.0 0.31 10.9 0.0 2.0 2 1 0 2 2 2 0 TAP-like protein Glyoxalase_2 PF12681.2 AIF82617.1 - 8.6e-09 35.9 0.0 1.2e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF82617.1 - 9.3e-06 25.6 0.0 5.9e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_2 PF00890.19 AIF82619.1 - 6.4e-91 305.2 1.5 8.5e-91 304.8 1.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AIF82619.1 - 1.8e-24 86.0 1.2 4e-24 84.9 0.3 2.0 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 AIF82619.1 - 4.7e-10 39.6 0.0 6.1e-08 32.7 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AIF82619.1 - 1.1e-07 30.7 1.2 0.00042 18.9 0.2 3.4 3 1 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 AIF82619.1 - 1.7e-05 24.1 1.9 3.6e-05 23.0 1.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AIF82619.1 - 0.00019 20.4 0.9 0.00059 18.8 0.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AIF82619.1 - 0.00036 19.4 0.2 0.00085 18.2 0.1 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 AIF82619.1 - 0.0012 19.2 1.3 0.034 14.5 0.2 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AIF82619.1 - 0.0026 16.9 0.2 0.11 11.6 0.0 2.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AIF82619.1 - 0.012 14.6 0.6 0.023 13.7 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 AIF82619.1 - 0.022 15.0 0.0 0.07 13.3 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 AIF82619.1 - 0.04 13.9 1.5 0.59 10.1 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Bombolitin PF08096.6 AIF82620.1 - 0.11 12.5 0.5 1.3 9.2 0.0 2.6 3 0 0 3 3 3 0 Bombolitin family DUF3892 PF13031.1 AIF82623.1 - 1e-10 41.8 0.1 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3892) Intimin_C PF07979.6 AIF82623.1 - 0.00027 21.0 0.0 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 Intimin C-type lectin domain Mucin PF01456.12 AIF82624.1 - 2.6 7.8 22.2 1.4 8.6 10.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein AsnC_trans_reg PF01037.16 AIF82625.1 - 1.5e-12 47.0 0.0 1.6e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 AIF82625.1 - 0.078 13.3 0.1 0.44 10.9 0.1 1.9 1 1 0 1 1 1 0 ACT domain NS3_envE PF02723.9 AIF82627.1 - 0.28 11.1 3.3 0.4 10.6 2.3 1.4 1 1 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E GSDH PF07995.6 AIF82628.1 - 4.7e-100 334.8 0.0 5.7e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Orai-1 PF07856.7 AIF82628.1 - 0.026 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity Reg_prop PF07494.6 AIF82628.1 - 0.037 14.0 0.0 60 4.1 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller PQQ_3 PF13570.1 AIF82628.1 - 2 8.7 4.8 92 3.5 0.1 4.2 4 1 1 5 5 5 0 PQQ-like domain PMSR PF01625.16 AIF82629.1 - 3.1e-63 212.3 0.9 3.6e-63 212.0 0.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SelR PF01641.13 AIF82630.1 - 5e-38 129.5 0.0 6.2e-38 129.2 0.0 1.0 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.3 AIF82630.1 - 0.0026 17.6 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 2 C-terminal domain of RIG-I Ribosomal_L37e PF01907.14 AIF82630.1 - 0.054 13.3 2.3 0.22 11.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e zf-HIT PF04438.11 AIF82630.1 - 0.067 12.8 2.0 0.47 10.1 0.3 2.2 2 0 0 2 2 2 0 HIT zinc finger RRN7 PF11781.3 AIF82630.1 - 0.091 12.2 3.9 0.64 9.5 1.3 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 AIF82630.1 - 0.14 11.9 3.5 1.9 8.3 2.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Mss51 PF13824.1 AIF82630.1 - 0.17 11.7 1.2 22 4.9 0.0 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2318 PF10080.4 AIF82630.1 - 0.18 11.5 0.7 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Rieske PF00355.21 AIF82631.1 - 1.3e-13 50.3 0.0 3.9e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain FMN_red PF03358.10 AIF82631.1 - 1.6e-13 50.4 0.0 2.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Rieske_2 PF13806.1 AIF82631.1 - 4.5e-08 32.7 0.0 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Flavodoxin_2 PF02525.12 AIF82631.1 - 0.0044 16.5 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold CBS PF00571.23 AIF82633.1 - 4e-30 103.3 5.6 1.9e-18 65.9 0.2 2.9 2 1 0 2 2 2 2 CBS domain ADK_lid PF05191.9 AIF82640.1 - 0.13 11.9 2.2 5.8 6.6 0.2 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF2667 PF10868.3 AIF82640.1 - 0.13 12.6 0.9 0.14 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2667) zf-RanBP PF00641.13 AIF82640.1 - 0.18 10.9 9.7 0.19 10.8 0.2 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-like PF04071.7 AIF82640.1 - 0.19 11.4 2.7 0.22 11.2 1.9 1.1 1 0 0 1 1 1 0 Cysteine-rich small domain zinc_ribbon_4 PF13717.1 AIF82640.1 - 0.21 11.3 6.6 4 7.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF82640.1 - 0.32 10.6 6.6 4.4 6.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.1 AIF82640.1 - 0.32 10.2 3.0 0.63 9.2 2.1 1.7 1 1 0 1 1 1 0 Transcription factor zinc-finger DUF4379 PF14311.1 AIF82640.1 - 5.7 6.8 7.0 0.46 10.3 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) zf-C2H2_jaz PF12171.3 AIF82641.1 - 0.13 12.4 1.9 0.3 11.2 1.3 1.7 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Band_7 PF01145.20 AIF82642.1 - 9.5e-23 81.0 13.0 2.5e-22 79.6 8.8 1.8 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF202 PF02656.10 AIF82642.1 - 0.0049 17.0 0.3 0.05 13.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) tRNA_NucTran2_2 PF13735.1 AIF82642.1 - 0.035 13.9 1.1 0.065 13.0 0.7 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF4381 PF14316.1 AIF82642.1 - 0.15 12.1 0.0 0.15 12.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Vpu PF00558.14 AIF82642.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 Vpu protein DUF1469 PF07332.6 AIF82642.1 - 0.44 10.2 0.0 0.44 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) LpxB PF02684.10 AIF82643.1 - 0.068 11.7 0.2 0.073 11.6 0.1 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Vasculin PF15337.1 AIF82643.1 - 0.55 10.7 4.2 9.5 6.7 0.3 2.2 1 1 1 2 2 2 0 Vascular protein family Vasculin-like 1 Herpes_LMP1 PF05297.6 AIF82645.1 - 1.8 7.4 6.3 0.3 9.9 1.9 1.5 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MOSP_C PF02722.10 AIF82646.1 - 0.11 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal region Collagen PF01391.13 AIF82647.1 - 0.0031 17.0 4.7 0.0031 17.0 3.3 2.2 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Glyco_hydro_67N PF03648.9 AIF82648.1 - 0.28 11.2 1.7 0.45 10.5 0.5 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 N-terminus VCBS PF13517.1 AIF82649.1 - 5.9e-15 55.3 19.0 2.6e-07 30.9 4.9 3.7 2 1 2 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 AIF82649.1 - 5.3e-05 22.7 13.4 1.4 8.7 0.4 4.6 4 0 0 4 4 4 4 FG-GAP repeat SnoaL PF07366.7 AIF82649.1 - 0.023 14.2 0.5 5.4 6.6 0.0 2.4 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase PLAT PF01477.18 AIF82649.1 - 0.26 11.6 9.0 0.5 10.7 2.8 2.8 1 1 2 3 3 3 0 PLAT/LH2 domain Cupin_1 PF00190.17 AIF82649.1 - 2.5 7.5 5.4 34 3.8 0.1 3.5 3 1 1 4 4 4 0 Cupin CAP PF00188.21 AIF82650.1 - 2.1e-05 25.0 0.8 9.3e-05 22.9 0.1 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF4611 PF15387.1 AIF82650.1 - 0.08 13.0 0.1 0.08 13.0 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 AIF82650.1 - 0.38 10.3 10.9 0.66 9.5 0.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Lon_C PF05362.8 AIF82652.1 - 1.3e-13 50.7 2.2 2.8e-13 49.6 1.5 1.4 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 AIF82652.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase BNR PF02012.15 AIF82652.1 - 0.11 12.4 6.1 24 5.3 0.1 4.5 3 0 0 3 3 3 0 BNR/Asp-box repeat Glyoxalase_2 PF12681.2 AIF82653.1 - 2.1e-10 41.1 0.3 9.5e-10 39.0 0.2 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF82653.1 - 2.5e-06 27.4 2.6 1.6e-05 24.8 1.8 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1995 PF09353.5 AIF82655.1 - 0.055 13.0 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) DUF4098 PF13345.1 AIF82655.1 - 0.12 12.2 0.1 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4098) DUF2313 PF10076.4 AIF82656.1 - 0.047 13.0 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) Ytp1 PF10355.4 AIF82657.1 - 0.61 9.2 7.6 0.15 11.2 2.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (Ytp1) Peptidase_U4 PF03419.8 AIF82657.1 - 4.3 6.3 10.6 5.7 5.9 7.3 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2127 PF09900.4 AIF82657.1 - 6.5 6.7 19.1 3.1 7.8 5.0 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2127) DUF4625 PF15418.1 AIF82658.1 - 1.1e-05 25.5 0.2 0.01 15.9 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) Big_3_4 PF13754.1 AIF82658.1 - 0.00054 20.2 2.9 0.00054 20.2 2.0 2.4 2 1 0 2 2 2 1 Bacterial Ig-like domain (group 3) Gmad2 PF10648.4 AIF82658.1 - 0.00078 19.5 0.2 0.0016 18.6 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin-like domain of bacterial spore germination GPI-anchored PF10342.4 AIF82658.1 - 0.017 15.5 2.4 0.027 14.9 1.7 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1736 PF08409.6 AIF82659.1 - 0.047 13.2 0.2 0.091 12.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1736) DUF3593 PF12159.3 AIF82659.1 - 0.37 10.6 2.6 0.45 10.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Presenilin PF01080.12 AIF82659.1 - 8 5.1 8.3 8 5.1 5.8 1.0 1 0 0 1 1 1 0 Presenilin Hexapep PF00132.19 AIF82660.1 - 3.8e-14 51.4 14.8 5.2e-05 22.5 0.1 4.5 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AIF82660.1 - 0.0008 18.9 7.0 0.024 14.1 1.0 3.9 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.20 AIF82661.1 - 1.6e-46 158.5 0.0 2e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AIF82661.1 - 7.7e-30 103.8 0.0 9.3e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AIF82661.1 - 9.3e-07 28.8 0.0 0.0042 16.8 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family DUF3357 PF11837.3 AIF82663.1 - 0.047 13.5 0.3 0.081 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Cas_Csy3 PF09615.5 AIF82663.1 - 0.16 11.0 0.1 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy3) N_NLPC_P60 PF12912.2 AIF82664.1 - 0.018 15.1 3.3 0.018 15.1 2.3 2.3 1 1 0 2 2 2 0 NLPC_P60 stabilising domain, N term DUF3359 PF11839.3 AIF82664.1 - 0.15 12.4 4.1 9.1 6.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) Serinc PF03348.10 AIF82664.1 - 0.23 10.1 1.4 0.38 9.4 0.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) FDF PF09532.5 AIF82664.1 - 5.3 7.6 8.9 0.43 11.1 0.2 3.0 3 0 0 3 3 3 0 FDF domain DUF385 PF04075.9 AIF82666.1 - 3.1e-12 46.6 0.2 3.5e-12 46.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF385) DUF2255 PF10012.4 AIF82666.1 - 1.5e-05 24.8 0.3 1.8e-05 24.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) Pyridox_oxidase PF01243.15 AIF82666.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LLGL PF08366.8 AIF82667.1 - 0.4 10.5 4.0 0.83 9.5 0.4 2.1 1 1 1 2 2 2 0 LLGL2 DUF4044 PF13253.1 AIF82667.1 - 0.99 8.6 4.6 11 5.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Dot_icm_IcmQ PF09475.5 AIF82667.1 - 1.4 8.0 5.5 1.9 7.6 1.1 1.9 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Cupredoxin_1 PF13473.1 AIF82668.1 - 4.6e-05 23.2 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 AIF82668.1 - 0.00073 19.7 0.0 0.0031 17.6 0.0 2.1 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DUF162 PF02589.10 AIF82668.1 - 0.022 14.2 0.1 0.022 14.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 CHB_HEX_C PF03174.8 AIF82670.1 - 1.6e-22 79.0 7.7 4.9e-22 77.5 5.4 1.9 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 AIF82670.1 - 3.4e-20 71.5 7.5 3.4e-20 71.5 5.2 2.1 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIF82670.1 - 6e-19 67.9 7.3 1.4e-18 66.6 5.1 1.7 1 0 0 1 1 1 1 Fn3 associated Polysacc_deac_1 PF01522.16 AIF82670.1 - 2.4e-10 40.1 0.0 4.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyoxalase PF00903.20 AIF82673.1 - 7e-21 74.5 0.3 3.9e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AIF82673.1 - 2.9e-18 66.4 0.1 8e-08 32.8 0.0 2.6 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AIF82673.1 - 3.1e-11 43.2 0.1 1e-05 25.4 0.0 2.9 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AIF82673.1 - 0.23 11.3 3.5 0.65 9.8 0.6 2.8 3 1 0 3 3 3 0 Glyoxalase-like domain HicB PF05534.7 AIF82675.1 - 0.016 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 HicB family ABM PF03992.11 AIF82676.1 - 5.9e-08 32.6 0.0 8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SOR PF07682.6 AIF82676.1 - 0.1 11.1 0.1 0.19 10.2 0.1 1.5 1 1 0 1 1 1 0 Sulphur oxygenase reductase Cu-oxidase_3 PF07732.10 AIF82677.1 - 2.4e-27 94.9 4.5 1.8e-22 79.2 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AIF82677.1 - 9.6e-17 60.7 16.3 4.3e-08 32.7 0.1 4.4 4 1 0 4 4 4 3 Multicopper oxidase Copper-bind PF00127.15 AIF82677.1 - 9.3e-12 45.0 3.6 3.3e-07 30.4 0.1 3.8 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF82677.1 - 2.3e-11 43.5 0.0 3.3e-07 30.1 0.0 3.8 3 2 0 3 3 3 3 Cupredoxin-like domain Hemerythrin PF01814.18 AIF82678.1 - 8.9e-11 42.0 2.8 8.9e-11 42.0 1.9 1.8 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain IlvC PF01450.14 AIF82678.1 - 0.12 12.3 0.2 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain AAA_5 PF07728.9 AIF82679.1 - 7.9e-28 96.9 0.0 1.2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AIF82679.1 - 4.7e-12 45.6 0.0 6.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AIF82679.1 - 3.1e-07 30.6 0.0 5.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AIF82679.1 - 1.8e-06 28.0 0.1 3.9e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 AIF82679.1 - 4.1e-06 26.7 0.0 7.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AIF82679.1 - 9.4e-06 25.4 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MCM PF00493.18 AIF82679.1 - 4.5e-05 22.4 0.0 7.7e-05 21.6 0.0 1.3 1 1 0 1 1 1 1 MCM2/3/5 family AAA_22 PF13401.1 AIF82679.1 - 0.0001 22.4 0.1 0.00025 21.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AIF82679.1 - 0.00012 21.2 0.1 0.0016 17.5 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AIF82679.1 - 0.00012 22.9 0.1 0.00026 21.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 AIF82679.1 - 0.00017 20.6 0.0 0.00021 20.3 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain MobB PF03205.9 AIF82679.1 - 0.00022 20.9 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AIF82679.1 - 0.00053 19.6 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Sigma54_activ_2 PF14532.1 AIF82679.1 - 0.0006 19.8 0.0 0.0033 17.4 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 AIF82679.1 - 0.00091 18.4 0.1 0.42 9.7 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AIF82679.1 - 0.00096 18.6 0.1 0.0028 17.1 0.1 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.1 AIF82679.1 - 0.001 18.6 0.2 0.0031 17.1 0.2 1.8 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 AIF82679.1 - 0.0014 18.2 0.1 0.0035 16.9 0.1 1.7 1 1 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 AIF82679.1 - 0.0017 18.0 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AIF82679.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 AIF82679.1 - 0.0021 18.5 0.0 0.01 16.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein SRP54 PF00448.17 AIF82679.1 - 0.0022 17.4 0.1 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 AIF82679.1 - 0.0024 17.8 0.3 0.0053 16.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 AIF82679.1 - 0.0041 16.9 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AIF82679.1 - 0.0046 15.9 0.0 0.0086 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 AIF82679.1 - 0.005 17.0 0.0 0.0094 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 AIF82679.1 - 0.0057 16.3 0.1 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_25 PF13481.1 AIF82679.1 - 0.006 16.0 0.1 0.013 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AIF82679.1 - 0.007 16.6 0.1 0.021 15.1 0.1 1.7 2 1 0 2 2 1 1 ABC transporter AAA_18 PF13238.1 AIF82679.1 - 0.0074 16.5 0.2 0.013 15.7 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AIF82679.1 - 0.012 15.2 0.1 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 AIF82679.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 AIF82679.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AIF82679.1 - 0.026 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbbQ_C PF08406.5 AIF82679.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal IstB_IS21 PF01695.12 AIF82679.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_35 PF14516.1 AIF82679.1 - 0.043 12.4 0.0 0.11 11.0 0.0 1.6 1 1 1 2 2 2 0 AAA-like domain AAA_23 PF13476.1 AIF82679.1 - 0.05 13.9 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 AIF82679.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 AIF82679.1 - 0.089 11.6 0.0 0.2 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) VWA PF00092.23 AIF82680.1 - 6.5e-07 29.2 0.0 2e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 AIF82680.1 - 2.5e-05 24.4 0.0 4.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 AIF82680.1 - 0.031 14.1 0.1 0.13 12.0 0.0 2.0 2 1 0 2 2 2 0 vWA found in TerF C terminus VWA_3 PF13768.1 AIF82680.1 - 0.033 13.8 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF3507 PF12015.3 AIF82680.1 - 0.047 13.1 0.2 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Transaldolase PF00923.14 AIF82681.1 - 1.6e-59 201.4 0.3 3e-58 197.2 0.2 2.1 1 1 0 1 1 1 1 Transaldolase Transket_pyr PF02779.19 AIF82682.1 - 3.8e-35 120.9 0.0 5.6e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AIF82682.1 - 2.9e-28 98.2 1.0 4.8e-28 97.5 0.2 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 AIF82683.1 - 2.8e-65 220.3 0.0 4.5e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Ribul_P_3_epim PF00834.14 AIF82683.1 - 2.5e-58 196.4 0.1 3.7e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family E1_dh PF00676.15 AIF82683.1 - 7e-09 34.8 0.1 1.3e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 AIF82683.1 - 6.2e-08 31.9 0.2 0.00037 19.5 0.1 3.0 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 AIF82683.1 - 0.00014 21.4 0.2 0.0019 17.7 0.1 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Radical_SAM PF04055.16 AIF82683.1 - 0.02 15.0 0.1 6.5 6.8 0.0 3.8 3 1 1 4 4 4 0 Radical SAM superfamily FYRN PF05964.9 AIF82684.1 - 0.0032 16.8 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus Peptidase_M17 PF00883.16 AIF82685.1 - 3.1e-114 381.0 0.0 3.8e-114 380.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 AIF82685.1 - 1.3e-20 73.3 0.3 3.8e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain DUF1294 PF06961.8 AIF82685.1 - 0.037 13.9 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Med25_VWA PF11265.3 AIF82685.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A ABC_tran PF00005.22 AIF82687.1 - 3.5e-38 130.9 0.0 4.7e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AIF82687.1 - 5e-11 42.2 1.7 0.00035 19.8 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIF82687.1 - 8.2e-11 42.3 5.1 0.14 12.1 0.0 4.2 2 2 1 3 3 3 3 AAA domain RLI PF04068.10 AIF82687.1 - 3.7e-10 39.1 1.4 9.2e-10 37.9 0.9 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 AIF82687.1 - 8e-08 31.5 3.3 8e-08 31.5 2.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.2 AIF82687.1 - 1.1e-05 25.0 12.2 9.3e-05 22.1 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain SbcCD_C PF13558.1 AIF82687.1 - 7.2e-05 22.6 0.2 0.32 10.9 0.1 2.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Fer4_21 PF14697.1 AIF82687.1 - 0.00015 21.5 10.2 0.00025 20.8 7.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 AIF82687.1 - 0.00028 21.1 9.8 0.00089 19.5 6.9 1.8 1 1 1 2 2 2 1 4Fe-4S dicluster domain DUF258 PF03193.11 AIF82687.1 - 0.00032 19.9 0.1 0.0081 15.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Fer4_11 PF13247.1 AIF82687.1 - 0.00071 19.4 3.2 0.0013 18.5 2.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIF82687.1 - 0.0008 19.1 11.0 0.003 17.3 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 AIF82687.1 - 0.001 18.5 0.2 0.037 13.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 AIF82687.1 - 0.0031 16.9 0.4 0.98 8.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain Fer4_10 PF13237.1 AIF82687.1 - 0.0036 17.0 1.5 0.0036 17.0 1.1 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Miro PF08477.8 AIF82687.1 - 0.0047 17.4 0.2 4.5 7.7 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein MMR_HSR1 PF01926.18 AIF82687.1 - 0.0051 16.7 0.4 0.19 11.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 AIF82687.1 - 0.0061 15.6 0.0 4 6.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Fer4_9 PF13187.1 AIF82687.1 - 0.01 16.0 11.9 0.021 15.0 8.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_17 PF13207.1 AIF82687.1 - 0.014 16.1 1.0 3.3 8.5 0.1 3.2 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AIF82687.1 - 0.015 15.3 1.9 4.6 7.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Fer4_16 PF13484.1 AIF82687.1 - 0.016 15.9 0.1 0.016 15.9 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 AIF82687.1 - 0.018 15.5 3.7 0.018 15.5 2.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 AIF82687.1 - 0.018 15.0 4.4 0.039 13.9 3.0 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_33 PF13671.1 AIF82687.1 - 0.025 14.4 0.8 1.6 8.5 0.0 3.1 4 0 0 4 4 2 0 AAA domain MobB PF03205.9 AIF82687.1 - 0.051 13.2 2.7 3.4 7.3 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 AIF82687.1 - 0.071 12.7 0.5 6.4 6.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 AIF82687.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.1 AIF82687.1 - 0.077 13.3 0.2 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AIF82687.1 - 0.1 12.5 0.9 27 4.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.17 AIF82687.1 - 0.14 10.9 3.0 0.33 9.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain VirE PF05272.6 AIF82687.1 - 0.14 11.5 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E FeoB_N PF02421.13 AIF82687.1 - 0.2 10.9 0.9 3.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ArgK PF03308.11 AIF82687.1 - 0.26 10.0 1.5 0.96 8.1 0.1 2.2 2 0 0 2 2 2 0 ArgK protein Fer4_4 PF12800.2 AIF82687.1 - 0.4 11.1 11.4 0.13 12.6 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 AIF82687.1 - 10 6.6 9.8 2 8.8 3.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Met_10 PF02475.11 AIF82688.1 - 1.1e-61 207.9 1.5 1.4e-61 207.5 1.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.5 AIF82688.1 - 5.9e-08 32.4 0.0 9.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 AIF82688.1 - 0.00012 22.1 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF82688.1 - 0.00017 22.0 0.0 0.00033 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF82688.1 - 0.00095 18.5 0.1 0.0022 17.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 AIF82688.1 - 0.002 17.3 0.3 0.002 17.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 AIF82688.1 - 0.042 12.7 0.3 0.051 12.5 0.2 1.3 1 1 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltrans_SAM PF10672.4 AIF82688.1 - 0.055 12.3 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase DUF2157 PF09925.4 AIF82689.1 - 0.0018 17.8 2.8 0.0023 17.5 1.9 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) Cytochrom_B_C PF00032.12 AIF82689.1 - 0.011 15.9 0.7 0.013 15.7 0.5 1.0 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Phage_holin_1 PF04531.8 AIF82689.1 - 0.014 15.4 0.5 0.016 15.2 0.3 1.1 1 0 0 1 1 1 0 Bacteriophage holin DUF350 PF03994.9 AIF82689.1 - 0.053 13.2 5.1 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) IncA PF04156.9 AIF82689.1 - 0.1 12.1 3.8 0.12 12.0 2.7 1.1 1 0 0 1 1 1 0 IncA protein Phage_holin_3 PF05106.7 AIF82689.1 - 0.18 11.8 3.8 0.17 11.8 2.1 1.3 1 1 0 1 1 1 0 Phage holin family (Lysis protein S) Tetraspannin PF00335.15 AIF82689.1 - 0.2 10.9 3.2 0.21 10.8 2.2 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF1469 PF07332.6 AIF82689.1 - 0.32 10.7 7.7 0.37 10.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4175 PF13779.1 AIF82689.1 - 0.52 7.9 1.9 0.59 7.7 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4064 PF13273.1 AIF82689.1 - 3.6 7.7 6.8 52 4.0 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4307 PF14155.1 AIF82689.1 - 7.9 6.3 8.2 6.1 6.6 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Dodecin PF07311.7 AIF82690.1 - 2.7e-22 78.5 2.5 2.9e-22 78.4 1.7 1.0 1 0 0 1 1 1 1 Dodecin AXH PF08517.7 AIF82690.1 - 0.11 12.6 0.2 0.12 12.5 0.1 1.0 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) 4HB_MCP_1 PF12729.2 AIF82691.1 - 1.5e-08 34.2 2.4 8.7e-07 28.4 0.2 2.3 2 0 0 2 2 2 2 Four helix bundle sensory module for signal transduction DUF835 PF05763.7 AIF82691.1 - 2.2e-06 27.2 0.0 5.9e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF835) KaiC PF06745.8 AIF82691.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC VMA21 PF09446.5 AIF82691.1 - 2.7 8.0 9.1 0.092 12.6 0.5 2.6 3 0 0 3 3 3 0 VMA21-like domain Acetyltransf_1 PF00583.19 AIF82692.1 - 1.1e-17 63.7 0.3 1.8e-17 63.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIF82692.1 - 7.2e-10 38.8 0.2 1.2e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIF82692.1 - 6.4e-09 35.4 0.2 1.3e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AIF82692.1 - 8.5e-09 35.5 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIF82692.1 - 1.1e-06 28.5 0.0 2.9e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AIF82692.1 - 6.6e-05 22.8 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AIF82692.1 - 0.00017 21.5 0.1 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AIF82692.1 - 0.0012 18.9 0.1 0.0018 18.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M50 PF02163.17 AIF82693.1 - 4.8e-16 58.2 9.0 1.8e-14 53.1 6.3 2.5 1 1 0 1 1 1 1 Peptidase family M50 Pribosyltran PF00156.22 AIF82695.1 - 5.3e-15 55.2 3.2 3.5e-13 49.3 1.6 2.8 1 1 1 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.1 AIF82695.1 - 0.00066 18.9 0.1 0.00089 18.5 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 AIF82695.1 - 0.004 16.4 0.1 0.0067 15.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase GARS_C PF02843.11 AIF82695.1 - 0.065 13.4 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain LemA PF04011.7 AIF82696.1 - 9.9e-48 161.7 1.3 1.2e-47 161.4 0.9 1.1 1 0 0 1 1 1 1 LemA family YkyA PF10368.4 AIF82696.1 - 0.059 12.7 1.0 0.1 11.9 0.6 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Blo-t-5 PF11642.3 AIF82696.1 - 0.066 12.9 0.1 0.2 11.4 0.0 1.7 1 1 1 2 2 2 0 Mite allergen Blo t 5 RabGAP-TBC PF00566.13 AIF82696.1 - 0.13 11.7 0.5 0.18 11.2 0.3 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain TPM PF04536.9 AIF82697.1 - 1.4e-12 47.4 0.0 5e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase RCR PF12273.3 AIF82697.1 - 0.19 12.3 4.0 6.6 7.2 0.9 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TBP PF00352.16 AIF82698.1 - 4.1e-61 202.3 0.1 5e-30 102.7 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AIF82698.1 - 3.9e-06 26.8 0.0 0.0046 16.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) UPF0047 PF01894.12 AIF82699.1 - 3e-37 127.0 0.0 3.5e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Peptidase_S24 PF00717.18 AIF82700.1 - 6.9e-09 35.2 2.1 1.3e-08 34.3 0.6 2.0 1 1 0 2 2 2 1 Peptidase S24-like TrbC PF04956.8 AIF82700.1 - 0.17 11.9 2.7 2 8.4 0.1 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family TPR_11 PF13414.1 AIF82702.1 - 3.5e-36 122.6 0.6 1.9e-09 37.0 0.0 4.3 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 AIF82702.1 - 6.5e-34 113.1 0.0 4.3e-06 26.2 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 AIF82702.1 - 3.9e-32 108.5 0.3 5.4e-06 25.7 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 AIF82702.1 - 1.4e-25 89.2 0.0 2.7e-08 34.2 0.0 4.4 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 AIF82702.1 - 6.9e-23 80.7 1.5 1.1e-05 25.6 0.1 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 AIF82702.1 - 1.8e-21 75.8 1.1 1.9e-05 24.4 0.0 5.2 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 AIF82702.1 - 3.5e-21 73.3 0.1 0.004 16.8 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 AIF82702.1 - 8.7e-21 72.5 0.8 0.00054 20.3 0.0 6.3 2 1 5 7 7 6 4 Tetratricopeptide repeat Apc3 PF12895.2 AIF82702.1 - 8.3e-18 64.3 0.0 1.1e-07 31.8 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AIF82702.1 - 8.4e-15 54.3 0.0 9.3e-06 25.4 0.1 3.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AIF82702.1 - 1.7e-12 46.5 4.8 0.11 12.7 0.0 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 AIF82702.1 - 2.9e-12 46.1 0.2 0.14 12.6 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat NARP1 PF12569.3 AIF82702.1 - 3.3e-10 39.3 0.5 0.0025 16.6 0.1 3.2 1 1 2 3 3 3 3 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 AIF82702.1 - 9.9e-10 37.4 0.6 0.49 10.3 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIF82702.1 - 1.7e-07 31.0 1.1 8.8 6.3 0.0 5.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 AIF82702.1 - 5.3e-07 28.9 0.4 0.00084 18.4 0.0 3.3 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 AIF82702.1 - 7.2e-07 28.9 0.4 4.4 7.3 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 AIF82702.1 - 8e-06 25.8 2.1 4.9 7.3 0.0 4.8 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 AIF82702.1 - 0.00019 21.5 0.2 0.53 10.8 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.15 AIF82702.1 - 0.00047 19.9 0.1 20 5.4 0.0 4.3 4 0 0 4 4 4 0 PPR repeat ChAPs PF09295.5 AIF82702.1 - 0.00088 18.1 0.0 0.0024 16.7 0.0 1.6 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 AIF82702.1 - 0.0011 18.9 0.7 0.69 9.8 0.1 3.2 2 2 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 AIF82702.1 - 0.0018 18.5 0.0 1.9 8.7 0.0 3.3 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TOM20_plant PF06552.7 AIF82702.1 - 0.002 17.7 0.0 0.9 9.0 0.0 3.5 3 1 0 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 DUF3856 PF12968.2 AIF82702.1 - 0.0041 16.9 0.1 1.1 9.0 0.0 3.9 2 1 2 4 4 4 1 Domain of Unknown Function (DUF3856) LUC7 PF03194.10 AIF82702.1 - 0.077 12.5 0.9 0.12 11.8 0.6 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF4363 PF14276.1 AIF82702.1 - 3.3 7.4 8.9 0.65 9.7 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) OrfB_IS605 PF01385.14 AIF82703.1 - 3.7e-24 85.3 5.6 5.6e-24 84.7 3.9 1.3 1 0 0 1 1 1 1 Probable transposase OrfB_Zn_ribbon PF07282.6 AIF82703.1 - 1.7e-17 62.8 0.7 3.4e-17 61.8 0.5 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 AIF82703.1 - 0.013 14.9 0.7 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF1451 PF07295.6 AIF82703.1 - 0.022 14.5 0.5 0.052 13.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DZR PF12773.2 AIF82703.1 - 0.026 14.3 0.2 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF82703.1 - 0.044 12.9 1.4 0.62 9.3 1.2 2.3 1 1 1 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AIF82703.1 - 0.12 11.6 0.1 6.2 6.2 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Nop PF01798.13 AIF82704.1 - 6.4e-52 174.8 2.7 1e-49 167.6 1.1 2.2 2 0 0 2 2 2 2 Putative snoRNA binding domain NOSIC PF08060.8 AIF82704.1 - 6.1e-19 67.5 0.1 7.5e-18 64.0 0.0 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain TAF1D PF15333.1 AIF82704.1 - 0.0087 15.8 0.3 0.015 15.0 0.2 1.3 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D Fibrillarin PF01269.12 AIF82705.1 - 2.6e-84 281.7 0.0 3e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin PCMT PF01135.14 AIF82705.1 - 0.00017 21.1 0.1 0.00024 20.6 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AIF82705.1 - 0.00061 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 AIF82705.1 - 0.001 19.8 0.0 0.0019 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 AIF82705.1 - 0.0098 15.4 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 AIF82705.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82705.1 - 0.087 12.5 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain RNase_HII PF01351.13 AIF82706.1 - 4.9e-45 153.6 0.5 5.8e-45 153.3 0.3 1.0 1 0 0 1 1 1 1 Ribonuclease HII PALP PF00291.20 AIF82707.1 - 4.2e-19 68.9 0.2 4.6e-18 65.5 0.1 2.6 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme TRM PF02005.11 AIF82708.1 - 4.7e-93 312.1 0.0 5.4e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 AIF82708.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 AIF82708.1 - 0.0016 17.8 0.1 0.0046 16.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 AIF82708.1 - 0.0041 16.2 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 AIF82708.1 - 0.011 15.7 0.1 0.021 14.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AIF82708.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 AIF82708.1 - 0.08 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase NAD_binding_9 PF13454.1 AIF82709.1 - 0.085 12.6 0.2 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding 4HB_MCP_1 PF12729.2 AIF82709.1 - 6.1 6.1 5.9 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FAD_binding_6 PF00970.19 AIF82710.1 - 9.1e-14 51.3 0.0 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AIF82710.1 - 1.3e-12 48.2 0.0 2.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AIF82710.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF424 PF04242.8 AIF82711.1 - 6.4e-15 54.9 0.1 7.1e-15 54.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) DUF1874 PF08960.5 AIF82711.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) RIO1 PF01163.17 AIF82712.1 - 2e-54 183.8 0.6 3.5e-54 183.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 AIF82712.1 - 7.4e-07 28.5 0.0 1.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AIF82712.1 - 3.5e-06 26.9 1.9 0.039 13.6 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 AIF82712.1 - 4.9e-05 22.4 0.0 0.00036 19.6 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AIF82712.1 - 0.055 12.4 0.2 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like FluMu_gp41 PF10109.4 AIF82712.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 KH_1 PF00013.24 AIF82713.1 - 1.5e-16 59.7 7.2 1.2e-08 34.4 1.6 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 AIF82713.1 - 1.2e-09 37.6 6.8 1.8e-05 24.2 0.7 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 AIF82713.1 - 0.0011 18.5 3.2 0.39 10.3 0.1 2.4 2 0 0 2 2 2 2 KH domain DUF3343 PF11823.3 AIF82713.1 - 0.062 12.5 0.3 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) KH_4 PF13083.1 AIF82713.1 - 0.11 12.1 1.7 3.3 7.3 0.1 2.7 2 0 0 2 2 2 0 KH domain GvpH PF05455.6 AIF82714.1 - 0.00098 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 GvpH Trep_Strep PF09605.5 AIF82714.1 - 0.05 13.2 1.5 0.072 12.7 1.0 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF3671 PF12420.3 AIF82714.1 - 0.12 12.3 0.2 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function RseC_MucC PF04246.7 AIF82714.1 - 0.14 11.7 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Flavoprotein PF02441.14 AIF82715.1 - 1.8e-30 105.2 0.6 2.5e-30 104.7 0.1 1.4 2 0 0 2 2 2 1 Flavoprotein CofC PF01983.11 AIF82715.1 - 0.056 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like PfkB PF00294.19 AIF82716.1 - 6.3e-25 87.9 0.0 9.4e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ABM PF03992.11 AIF82717.1 - 1.4e-08 34.6 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ferritin PF00210.19 AIF82718.1 - 6.8e-22 77.7 0.1 8e-22 77.5 0.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AIF82718.1 - 0.00021 21.6 0.0 0.0003 21.1 0.0 1.3 1 0 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.1 AIF82718.1 - 0.0029 17.5 0.1 0.0035 17.2 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain TrmB PF01978.14 AIF82719.1 - 9.3e-09 34.8 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PNP_UDP_1 PF01048.15 AIF82722.1 - 2.6e-44 150.9 0.0 3e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pribosyltran PF00156.22 AIF82723.1 - 5.2e-16 58.5 0.2 7e-16 58.0 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AIF82723.1 - 2.4e-05 23.6 0.0 3.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Peptidase_M10 PF00413.19 AIF82724.1 - 0.032 13.9 0.1 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Matrixin HpaB_N PF11794.3 AIF82725.1 - 1.8e-89 299.6 0.0 2.7e-89 299.0 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.8 AIF82725.1 - 4.1e-74 247.8 0.2 5.5e-74 247.4 0.1 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Glyoxalase_2 PF12681.2 AIF82726.1 - 3.5e-14 53.3 0.0 4.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF82726.1 - 4.5e-06 26.6 0.0 2.9e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RNA_pol_Rpc34 PF05158.7 AIF82727.1 - 5.7e-06 25.7 0.6 0.00015 21.0 0.2 2.1 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit MarR PF01047.17 AIF82727.1 - 0.011 15.3 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 MarR family B-block_TFIIIC PF04182.7 AIF82727.1 - 0.037 13.8 0.1 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC MarR_2 PF12802.2 AIF82727.1 - 0.038 13.6 0.2 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 MarR family FtsJ PF01728.14 AIF82728.1 - 9.8e-56 188.5 0.0 1.1e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 AIF82728.1 - 4.8e-07 29.4 0.0 5.8e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82728.1 - 1.5e-05 24.7 0.0 5.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF82728.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF82728.1 - 0.018 15.5 0.0 0.088 13.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AIF82728.1 - 0.04 14.2 0.0 0.23 11.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain NSP13 PF06460.7 AIF82728.1 - 0.046 12.6 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 Methyltransf_18 PF12847.2 AIF82728.1 - 0.082 13.4 0.1 0.36 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltrans_Mon PF14314.1 AIF82728.1 - 0.12 10.2 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase DUF373 PF04123.8 AIF82729.1 - 6.4e-100 334.5 9.6 7.8e-100 334.2 6.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF202 PF02656.10 AIF82729.1 - 5.7 7.2 11.5 8.5 6.6 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4231 PF14015.1 AIF82729.1 - 6.2 6.8 12.0 35 4.4 5.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF4227 PF14004.1 AIF82730.1 - 0.04 13.7 0.1 0.048 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Ribosomal_60s PF00428.14 AIF82730.1 - 3.3 8.1 7.9 3.8 7.9 5.5 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abhydrolase_9_N PF15420.1 AIF82731.1 - 0.04 13.6 1.1 0.043 13.5 0.8 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus VitK2_biosynth PF02621.9 AIF82731.1 - 0.057 12.5 0.1 0.062 12.4 0.1 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis Nodulin-like PF06813.8 AIF82731.1 - 0.065 12.4 4.5 0.072 12.3 3.1 1.0 1 0 0 1 1 1 0 Nodulin-like MscL PF01741.13 AIF82731.1 - 0.065 13.3 0.7 0.078 13.1 0.5 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF2929 PF11151.3 AIF82731.1 - 0.11 12.5 4.3 0.41 10.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) FxsA PF04186.8 AIF82731.1 - 0.12 12.0 2.1 0.18 11.4 1.5 1.3 1 1 0 1 1 1 0 FxsA cytoplasmic membrane protein ABC2_membrane_4 PF12730.2 AIF82731.1 - 0.12 11.5 6.0 0.16 11.1 4.2 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein PrgI PF12666.2 AIF82731.1 - 0.23 11.6 2.9 0.34 11.0 2.0 1.3 1 1 0 1 1 1 0 PrgI family protein Oxidored_q2 PF00420.19 AIF82731.1 - 0.38 10.3 7.9 0.59 9.7 5.5 1.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L GPI2 PF06432.6 AIF82731.1 - 0.63 9.3 4.5 0.93 8.7 0.1 2.0 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2207 PF09972.4 AIF82731.1 - 0.71 8.3 3.2 0.77 8.2 2.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1361 PF07099.6 AIF82731.1 - 0.73 9.6 6.5 0.86 9.3 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) ATP_synt_I PF03899.10 AIF82731.1 - 0.74 10.0 7.7 0.96 9.6 5.3 1.1 1 0 0 1 1 1 0 ATP synthase I chain DUF202 PF02656.10 AIF82731.1 - 1.5 9.0 4.6 1.3 9.2 2.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Peptidase_U4 PF03419.8 AIF82731.1 - 1.9 7.4 8.1 4 6.4 5.6 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA NUDIX PF00293.23 AIF82732.1 - 4.2e-17 62.0 0.0 5.3e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 AIF82732.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain OMPdecase PF00215.19 AIF82733.1 - 3e-30 105.2 0.6 3.8e-30 104.9 0.4 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 AIF82733.1 - 0.021 14.0 0.9 0.15 11.2 0.2 2.4 2 1 1 3 3 3 0 PcrB family Peripla_BP_4 PF13407.1 AIF82733.1 - 0.066 12.5 0.4 0.61 9.3 0.1 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain RapA_C PF12137.3 AIF82733.1 - 0.086 11.6 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase recycling family C-terminal ALIX_LYPXL_bnd PF13949.1 AIF82735.1 - 0.062 12.2 0.1 0.071 12.0 0.1 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV FUSC PF04632.7 AIF82735.1 - 0.15 10.4 2.6 0.16 10.3 1.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Adenylsucc_synt PF00709.16 AIF82736.1 - 6e-85 285.4 0.3 5.3e-40 137.3 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase Iron_traffic PF04362.9 AIF82738.1 - 1.6e-08 33.8 0.0 2.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking zinc_ribbon_2 PF13240.1 AIF82738.1 - 0.096 12.2 0.4 0.2 11.1 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain YhfH PF14149.1 AIF82738.1 - 0.21 11.3 0.3 0.21 11.3 0.2 1.8 2 0 0 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.1 AIF82738.1 - 2.4 7.4 4.7 5.5 6.3 3.3 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Laminin_EGF PF00053.19 AIF82739.1 - 0.025 14.5 1.1 0.035 14.0 0.8 1.2 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) DZR PF12773.2 AIF82739.1 - 0.03 14.1 1.2 0.045 13.5 0.9 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF82739.1 - 0.097 11.9 3.6 0.38 10.0 2.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF82739.1 - 0.25 10.8 1.7 8.6 5.9 1.7 2.2 1 1 1 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AIF82739.1 - 0.77 9.2 3.2 6.1 6.4 2.2 2.1 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.1 AIF82740.1 - 0.00072 19.1 3.4 0.0081 15.8 2.4 2.0 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF82740.1 - 0.00088 18.8 3.7 0.0077 15.7 2.6 2.0 1 1 0 1 1 1 1 zinc-ribbon domain IBR PF01485.16 AIF82740.1 - 0.006 16.4 1.0 0.0091 15.8 0.7 1.3 1 0 0 1 1 1 1 IBR domain zinc_ribbon_6 PF14599.1 AIF82740.1 - 0.0078 15.9 0.7 0.01 15.6 0.5 1.2 1 0 0 1 1 1 1 Zinc-ribbon Ribosomal_S27e PF01667.12 AIF82740.1 - 0.018 14.5 3.8 0.11 12.0 2.6 1.9 1 1 0 1 1 1 0 Ribosomal protein S27 Lar_restr_allev PF14354.1 AIF82740.1 - 0.03 14.6 3.6 0.48 10.7 0.2 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF2387 PF09526.5 AIF82740.1 - 0.061 13.2 2.5 0.11 12.4 1.7 1.4 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-DNL PF05180.7 AIF82740.1 - 0.069 12.8 1.5 0.28 10.9 0.9 1.9 1 1 1 2 2 2 0 DNL zinc finger zinc-ribbons_6 PF07191.7 AIF82740.1 - 0.081 12.7 0.4 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons HypA PF01155.14 AIF82740.1 - 0.087 12.5 0.3 0.094 12.4 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF329 PF03884.9 AIF82740.1 - 0.11 12.0 1.8 0.68 9.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF329) Glutaredoxin PF00462.19 AIF82740.1 - 0.13 12.2 1.6 0.16 11.9 1.1 1.4 1 1 0 1 1 1 0 Glutaredoxin zf-ribbon_3 PF13248.1 AIF82740.1 - 0.24 10.6 3.5 0.84 8.9 2.1 2.0 2 1 1 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 AIF82740.1 - 0.33 10.7 4.7 0.68 9.7 1.2 2.1 1 1 1 2 2 2 0 PhnA Zinc-Ribbon C1_3 PF07649.7 AIF82740.1 - 2 8.5 6.1 0.5 10.4 0.6 2.1 1 1 1 2 2 2 0 C1-like domain CybS PF05328.7 AIF82741.1 - 0.043 13.4 0.2 0.043 13.4 0.1 2.1 3 0 0 3 3 3 0 CybS MAPEG PF01124.13 AIF82741.1 - 0.16 11.5 4.7 0.19 11.3 2.2 1.9 2 0 0 2 2 2 0 MAPEG family HTH_45 PF14947.1 AIF82742.1 - 4.7e-12 45.5 0.0 2.5e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix Mrr_N PF14338.1 AIF82742.1 - 0.00072 19.5 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Mrr N-terminal domain Cdc6_C PF09079.6 AIF82742.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 CDC6, C terminal PMT_2 PF13231.1 AIF82743.1 - 4.1e-06 26.7 19.7 4.1e-06 26.7 13.7 3.8 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Big_3_4 PF13754.1 AIF82744.1 - 3.6e-06 27.2 0.5 1.3e-05 25.4 0.2 2.1 1 1 1 2 2 2 1 Bacterial Ig-like domain (group 3) Mo-co_dimer PF03404.11 AIF82744.1 - 0.00088 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Glycos_transf_2 PF00535.21 AIF82745.1 - 2e-28 99.1 0.0 3.5e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.9 AIF82745.1 - 5.9e-22 77.8 10.9 3.3e-21 75.4 7.9 1.9 1 1 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.1 AIF82745.1 - 1.2e-12 48.1 0.0 1.8e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AIF82745.1 - 0.00045 19.3 0.0 0.00093 18.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AIF82745.1 - 0.0038 16.5 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Methyltransf_2 PF00891.13 AIF82745.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase YjbR PF04237.8 AIF82746.1 - 0.056 13.7 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 YjbR Nucleoplasmin PF03066.10 AIF82747.1 - 0.68 9.4 8.7 0.78 9.2 6.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin ADH_N PF08240.7 AIF82748.1 - 2.3e-31 107.7 2.2 5.3e-31 106.6 0.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIF82748.1 - 5.5e-07 29.2 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 AIF82748.1 - 9.4e-06 25.1 0.6 9.4e-06 25.1 0.4 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 AIF82748.1 - 0.011 14.2 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 AIF82748.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 AIF82748.1 - 0.12 13.3 0.0 0.25 12.2 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF892 PF05974.7 AIF82749.1 - 6.9e-16 58.4 6.6 1.1e-15 57.7 4.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF892) Ferritin PF00210.19 AIF82749.1 - 0.0077 15.9 1.9 0.08 12.7 1.1 2.1 1 1 1 2 2 2 1 Ferritin-like domain NIT PF08376.5 AIF82749.1 - 0.025 14.0 2.5 0.04 13.4 1.7 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing Lzipper-MIP1 PF14389.1 AIF82749.1 - 0.042 13.9 2.5 2.9 8.0 0.3 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF2383 PF09537.5 AIF82749.1 - 0.14 12.3 2.1 0.61 10.3 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) NifQ PF04891.7 AIF82749.1 - 0.15 12.1 1.3 0.27 11.3 0.5 1.7 1 1 1 2 2 2 0 NifQ Tektin PF03148.9 AIF82749.1 - 0.58 8.6 5.8 1.1 7.7 4.0 1.5 1 1 0 1 1 1 0 Tektin family TM_helix PF05552.7 AIF82750.1 - 9.7e-17 60.3 15.4 1.1e-09 37.8 1.0 3.6 3 0 0 3 3 3 2 Conserved TM helix MS_channel PF00924.13 AIF82750.1 - 8e-13 48.1 2.3 2.3e-12 46.6 1.6 1.8 1 0 0 1 1 1 1 Mechanosensitive ion channel Colicin_V PF02674.11 AIF82750.1 - 0.005 16.6 22.9 0.18 11.6 0.2 3.1 2 1 1 3 3 3 2 Colicin V production protein DUF2798 PF11391.3 AIF82750.1 - 5.6 6.7 15.6 0.73 9.6 0.3 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF2798) DUF2382 PF09557.5 AIF82751.1 - 1e-25 89.8 25.4 1.6e-25 89.1 17.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2382) MIP PF00230.15 AIF82752.1 - 1.2e-47 162.3 19.5 1.3e-47 162.1 13.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein SPW PF03779.9 AIF82752.1 - 0.28 10.5 0.0 0.28 10.5 0.0 3.1 4 0 0 4 4 4 0 SPW repeat DUF4401 PF14351.1 AIF82752.1 - 0.29 10.0 17.5 0.32 9.9 9.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF2171 PF09939.4 AIF82753.1 - 2e-05 24.4 0.1 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2171) PRC PF05239.11 AIF82753.1 - 0.018 14.9 0.6 9.2 6.2 0.1 2.8 2 1 0 2 2 2 0 PRC-barrel domain NHL PF01436.16 AIF82756.1 - 7.1e-10 38.3 9.4 0.069 13.1 0.0 6.3 7 0 0 7 7 7 3 NHL repeat Cytochrom_D1 PF02239.11 AIF82756.1 - 2.5e-09 35.9 0.8 0.0004 18.7 0.0 3.1 2 1 1 3 3 3 3 Cytochrome D1 heme domain PufQ PF05398.6 AIF82756.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 PufQ cytochrome subunit DUF2946 PF11162.3 AIF82757.1 - 0.0012 19.0 7.3 0.0015 18.7 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) BAF1_ABF1 PF04684.8 AIF82757.1 - 0.053 12.3 15.6 0.055 12.3 10.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NicO PF03824.11 AIF82757.1 - 0.48 9.6 8.9 0.57 9.4 6.2 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein FAM177 PF14774.1 AIF82759.1 - 0.02 14.8 0.1 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 FAM177 family Ca_chan_IQ PF08763.6 AIF82759.1 - 0.072 12.3 0.1 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain THAP PF05485.7 AIF82759.1 - 0.53 10.4 5.2 3 8.0 0.5 2.1 1 1 1 2 2 2 0 THAP domain tRNA-Thr_ED PF08915.6 AIF82760.1 - 1.7e-46 157.6 0.5 3.6e-46 156.5 0.3 1.6 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.15 AIF82760.1 - 3.8e-25 87.6 2.4 9.8e-25 86.3 1.7 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 AIF82760.1 - 7.5e-25 87.4 1.8 1.5e-24 86.5 1.3 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Arginase PF00491.16 AIF82761.1 - 1.9e-56 191.3 0.0 2.4e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family DNA_pol_B PF00136.16 AIF82762.1 - 2.5e-80 270.5 0.1 2.5e-80 270.5 0.0 1.7 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AIF82762.1 - 5e-36 124.2 0.2 9e-36 123.3 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.4 AIF82762.1 - 0.00011 21.7 0.0 0.00032 20.2 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 AIF82762.1 - 0.00048 19.9 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily Vinculin PF01044.14 AIF82762.1 - 0.29 9.1 0.0 0.41 8.5 0.0 1.1 1 0 0 1 1 1 0 Vinculin family DAO PF01266.19 AIF82763.1 - 8.7e-42 143.2 0.0 1.5e-41 142.5 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 AIF82763.1 - 3.1e-09 35.5 0.0 1.6e-07 29.8 0.0 2.2 2 1 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 AIF82763.1 - 7.7e-05 22.6 0.0 0.0033 17.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIF82763.1 - 0.0022 17.0 0.2 1.5 7.6 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 AIF82763.1 - 0.0022 17.9 0.0 0.008 16.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AIF82763.1 - 0.011 16.0 0.0 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIF82763.1 - 0.015 15.3 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AIF82763.1 - 0.061 12.3 0.3 5.4 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 AIF82763.1 - 0.074 11.5 0.1 0.22 9.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 AIF82763.1 - 0.085 11.4 0.4 7.8 4.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase PIN PF01850.16 AIF82764.1 - 7.8e-08 32.6 0.2 1.1e-07 32.2 0.1 1.2 1 0 0 1 1 1 1 PIN domain DUF2827 PF10933.3 AIF82764.1 - 0.086 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) CcdA PF07362.7 AIF82765.1 - 0.00011 22.0 1.9 0.00012 21.8 1.2 1.3 1 1 0 1 1 1 1 Post-segregation antitoxin CcdA RHH_1 PF01402.16 AIF82765.1 - 0.0054 16.5 2.0 0.011 15.5 0.5 2.3 1 1 1 2 2 2 1 Ribbon-helix-helix protein, copG family DUF2115 PF09888.4 AIF82765.1 - 0.015 15.4 1.6 0.016 15.3 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) SAP PF02037.22 AIF82765.1 - 0.019 14.4 0.2 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 SAP domain DUF3007 PF11460.3 AIF82765.1 - 0.063 13.3 2.1 0.081 13.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Ribosomal_L5 PF00281.14 AIF82765.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L5 60KD_IMP PF02096.15 AIF82765.1 - 0.11 12.1 0.9 0.13 11.8 0.6 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein Dpoe2NT PF12213.3 AIF82765.1 - 0.11 12.3 2.3 0.18 11.7 1.6 1.5 1 1 0 1 1 1 0 DNA polymerases epsilon N terminal AAA_18 PF13238.1 AIF82765.1 - 0.13 12.5 1.4 0.15 12.3 1.0 1.1 1 0 0 1 1 1 0 AAA domain Intron_maturas2 PF01348.16 AIF82765.1 - 0.14 12.0 0.6 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 Type II intron maturase MT0933_antitox PF14013.1 AIF82765.1 - 0.23 11.5 3.9 0.75 9.9 2.7 1.8 1 1 0 1 1 1 0 MT0933-like antitoxin protein Histone_HNS PF00816.16 AIF82765.1 - 0.25 11.8 6.9 2.9 8.4 4.2 2.0 1 1 1 2 2 2 0 H-NS histone family OmpH PF03938.9 AIF82765.1 - 0.28 11.0 4.9 0.71 9.8 3.5 1.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Bac_DNA_binding PF00216.16 AIF82765.1 - 0.35 10.9 4.9 4.9 7.2 0.0 2.4 2 1 0 2 2 2 0 Bacterial DNA-binding protein Spore_III_AF PF09581.5 AIF82765.1 - 0.39 10.5 5.1 0.65 9.8 3.4 1.5 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Con-6 PF10346.4 AIF82765.1 - 0.43 10.0 3.3 0.56 9.6 1.0 2.1 1 1 1 2 2 2 0 Conidiation protein 6 AHH PF14412.1 AIF82765.1 - 0.77 9.7 3.7 10 6.1 1.6 2.1 1 1 1 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH GreA_GreB_N PF03449.10 AIF82765.1 - 1.6 8.8 9.3 1.1 9.3 3.5 2.4 1 1 2 3 3 3 0 Transcription elongation factor, N-terminal HK97-gp10_like PF04883.7 AIF82765.1 - 2 9.3 6.7 3.4 8.6 2.8 2.0 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component YtxH PF12732.2 AIF82765.1 - 5.3 7.4 6.6 19 5.6 4.5 1.8 1 1 0 1 1 1 0 YtxH-like protein NurA PF09376.5 AIF82767.1 - 3.4e-13 49.6 0.0 9.1e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 NurA domain gerPA PF10676.4 AIF82767.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF DUF87 PF01935.12 AIF82768.1 - 3.5e-36 125.1 0.2 6.6e-36 124.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 AIF82768.1 - 3.9e-18 65.9 0.5 1.1e-16 61.1 0.4 2.1 1 1 0 1 1 1 1 AAA-like domain DUF853 PF05872.7 AIF82768.1 - 0.00029 19.3 0.1 0.045 12.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) HAS-barrel PF09378.5 AIF82768.1 - 0.00036 20.3 0.1 0.0013 18.5 0.1 2.0 2 0 0 2 2 2 1 HAS barrel domain FtsK_SpoIIIE PF01580.13 AIF82768.1 - 0.00076 19.0 0.4 0.94 8.9 0.0 2.7 3 1 0 3 3 3 2 FtsK/SpoIIIE family Zot PF05707.7 AIF82768.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.4 AIF82768.1 - 0.0065 15.1 0.1 0.022 13.3 0.0 1.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 AIF82768.1 - 0.0082 16.4 0.0 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter DUF2283 PF10049.4 AIF82770.1 - 5.9e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) Metallophos_2 PF12850.2 AIF82771.1 - 1.6e-15 57.3 0.1 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AIF82771.1 - 1.2e-11 44.3 0.2 2e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SMC_N PF02463.14 AIF82772.1 - 3.1e-25 88.6 3.2 3.1e-24 85.4 2.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AIF82772.1 - 1.8e-16 61.0 22.8 8.8e-13 49.0 15.8 3.6 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 AIF82772.1 - 7.4e-15 55.6 0.0 1.6e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AIF82772.1 - 7e-14 51.6 2.5 6.7e-07 28.6 0.0 3.2 4 0 0 4 4 4 2 AAA ATPase domain AAA_13 PF13166.1 AIF82772.1 - 3.1e-11 42.4 20.7 5.1e-07 28.5 12.9 3.8 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 AIF82772.1 - 3.7e-10 39.5 0.0 1.3e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AIF82772.1 - 4.7e-08 32.4 0.0 1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AIF82772.1 - 1.1e-05 25.7 6.0 0.021 15.1 0.1 3.5 3 3 0 3 3 3 2 ABC transporter DUF258 PF03193.11 AIF82772.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DNA_ligase_ZBD PF03119.11 AIF82772.1 - 0.02 14.5 0.1 0.051 13.2 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Miro PF08477.8 AIF82772.1 - 0.031 14.7 0.2 10 6.6 0.1 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 AIF82772.1 - 0.047 13.5 0.0 0.37 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-C3HC4_3 PF13920.1 AIF82772.1 - 0.21 11.2 0.7 0.35 10.5 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NPV_P10 PF05531.7 AIF82772.1 - 3.8 7.8 6.5 5.6 7.2 0.2 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HTH_24 PF13412.1 AIF82773.1 - 2.4e-08 33.2 1.3 6.3e-08 31.8 0.9 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF82773.1 - 2e-06 27.1 0.5 5.9e-06 25.7 0.4 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain TrmB PF01978.14 AIF82773.1 - 0.00087 18.9 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AIF82773.1 - 0.11 12.2 0.4 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.1 AIF82773.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4179 PF13786.1 AIF82775.1 - 0.023 14.8 0.5 0.023 14.8 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CENP-T PF15511.1 AIF82775.1 - 0.25 10.5 4.1 0.28 10.3 2.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1183 PF06682.7 AIF82775.1 - 0.59 9.6 13.2 0.11 12.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Daxx PF03344.10 AIF82775.1 - 3.4 6.0 9.4 4.4 5.6 6.5 1.1 1 0 0 1 1 1 0 Daxx Family Transposase_20 PF02371.11 AIF82777.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family FG-GAP PF01839.18 AIF82779.1 - 1.6e-53 177.1 67.0 2.9e-09 36.3 2.5 7.5 7 0 0 7 7 7 7 FG-GAP repeat VCBS PF13517.1 AIF82779.1 - 6.6e-24 84.0 53.3 1.4e-06 28.5 3.8 6.3 5 2 1 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 AIF82779.1 - 8.8e-09 35.0 21.3 0.017 14.6 0.1 7.3 6 1 1 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region Phospholip_A2_3 PF09056.6 AIF82779.1 - 0.068 13.3 2.1 16 5.7 0.0 3.9 4 0 0 4 4 4 0 Prokaryotic phospholipase A2 BBS2_Mid PF14783.1 AIF82779.1 - 0.22 11.3 1.4 1.3e+02 2.3 0.0 5.1 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region DUF2919 PF11143.3 AIF82781.1 - 0.028 14.2 0.3 0.05 13.4 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2919) DUF3707 PF12499.3 AIF82782.1 - 1.6 9.0 7.0 1.1 9.5 0.4 3.6 3 1 0 3 3 3 0 Pherophorin Baculo_PEP_C PF04513.7 AIF82783.1 - 0.0039 17.0 2.5 0.0059 16.4 1.8 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 AIF82783.1 - 0.016 14.9 0.4 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF948 PF06103.6 AIF82783.1 - 0.023 14.5 0.1 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 AIF82783.1 - 0.05 13.1 0.1 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MAD PF05557.8 AIF82783.1 - 0.055 11.5 0.3 0.071 11.1 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein HSCB_C PF07743.8 AIF82783.1 - 0.069 13.6 0.3 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain YtkA PF13115.1 AIF82783.1 - 0.091 13.1 0.0 0.57 10.5 0.0 2.3 2 1 0 2 2 2 0 YtkA-like H-kinase_dim PF02895.9 AIF82783.1 - 0.097 13.0 0.7 0.29 11.4 0.2 1.9 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF432 PF04254.8 AIF82783.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) DUF1664 PF07889.7 AIF82783.1 - 0.15 11.8 0.2 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Polysacc_deac_1 PF01522.16 AIF82784.1 - 7.1e-10 38.5 0.0 1.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase UPF0180 PF03698.8 AIF82784.1 - 0.11 12.3 0.1 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Hexapep PF00132.19 AIF82786.1 - 1.3e-29 100.3 25.3 1.1e-09 37.3 5.1 4.3 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AIF82786.1 - 7.1e-09 35.0 26.0 0.014 14.9 3.3 4.8 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.21 AIF82787.1 - 2.1e-11 43.8 0.0 2.4e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIF82787.1 - 7.1e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Methyltransf_23 PF13489.1 AIF82789.1 - 2.5e-11 43.5 0.0 2.9e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF82789.1 - 7.2e-11 41.8 0.0 8.6e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF82789.1 - 1.7e-10 41.2 0.1 2.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF82789.1 - 2.4e-10 40.7 0.0 3.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AIF82789.1 - 2.3e-09 36.8 0.1 3.3e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.2 AIF82789.1 - 4.6e-06 27.1 0.1 7.1e-06 26.5 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF82789.1 - 7.9e-05 22.9 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 AIF82789.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PDH PF02153.12 AIF82789.1 - 0.00038 19.4 0.2 0.0005 19.0 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase TehB PF03848.9 AIF82789.1 - 0.0012 18.0 0.1 0.0028 16.8 0.1 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 AIF82789.1 - 0.0062 16.5 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 AIF82789.1 - 0.0068 15.3 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme TrkA_N PF02254.13 AIF82789.1 - 0.019 14.9 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_4 PF02390.12 AIF82789.1 - 0.029 13.4 0.1 0.05 12.6 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 AIF82789.1 - 0.039 13.0 0.0 0.053 12.6 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AIF82789.1 - 0.054 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_L1 PF00687.16 AIF82791.1 - 1e-41 142.7 0.1 1.3e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Activator-TraM PF11657.3 AIF82791.1 - 0.022 14.2 0.2 0.049 13.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional activator TraM Ribosomal_L10 PF00466.15 AIF82792.1 - 5.2e-19 68.0 2.3 1.4e-18 66.6 1.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 zinc_ribbon_5 PF13719.1 AIF82793.1 - 0.66 9.6 4.0 0.66 9.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIF82793.1 - 0.67 9.6 3.8 0.83 9.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 AIF82793.1 - 1.8 7.7 5.7 5.5 6.1 4.0 1.8 1 1 0 1 1 1 0 Mu-like prophage protein Com Ribosomal_60s PF00428.14 AIF82795.1 - 2.9e-18 66.0 15.7 3.3e-18 65.8 10.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF348 PF03990.9 AIF82795.1 - 0.097 12.2 1.0 0.61 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF348) PepSY_2 PF13670.1 AIF82795.1 - 0.11 12.4 5.9 2 8.3 2.9 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Qn_am_d_aIII PF09099.5 AIF82796.1 - 0.04 14.2 0.1 0.15 12.4 0.0 2.0 2 1 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Pex14_N PF04695.8 AIF82796.1 - 0.4 10.7 8.3 0.69 9.9 0.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FtsH_ext PF06480.10 AIF82796.1 - 1.9 8.6 5.7 2.5 8.3 0.4 2.5 2 0 0 2 2 2 0 FtsH Extracellular HTH_5 PF01022.15 AIF82798.1 - 0.00023 20.7 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF82798.1 - 0.003 17.1 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF82798.1 - 0.0034 17.0 0.0 0.0067 16.1 0.0 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AIF82798.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_28 PF13518.1 AIF82798.1 - 0.0075 16.2 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 AIF82798.1 - 0.011 15.0 0.3 0.025 13.9 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Phage_AlpA PF05930.7 AIF82798.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_45 PF14947.1 AIF82798.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix Mga PF05043.8 AIF82798.1 - 0.027 14.7 0.1 0.056 13.7 0.0 1.6 1 1 1 2 2 2 0 Mga helix-turn-helix domain HTH_23 PF13384.1 AIF82798.1 - 0.03 13.9 0.0 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.10 AIF82798.1 - 0.032 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_20 PF12840.2 AIF82798.1 - 0.068 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.1 AIF82798.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF95 PF01944.12 AIF82799.1 - 0.057 13.0 3.5 0.075 12.6 2.4 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF95 DUF1056 PF06341.6 AIF82799.1 - 1.3 9.1 7.2 7 6.7 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) Pox_P21 PF05313.7 AIF82800.1 - 0.023 13.9 0.3 0.028 13.6 0.2 1.0 1 0 0 1 1 1 0 Poxvirus P21 membrane protein ABC2_membrane_5 PF13346.1 AIF82800.1 - 0.046 12.9 6.7 0.052 12.8 4.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein CobS PF02654.10 AIF82800.1 - 0.054 13.0 0.7 0.062 12.8 0.5 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase Exosortase_EpsH PF09721.5 AIF82800.1 - 0.089 11.9 1.9 0.094 11.9 0.7 1.4 1 1 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) DUF3007 PF11460.3 AIF82800.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) HXXEE PF13787.1 AIF82800.1 - 0.23 11.8 5.7 0.34 11.3 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif DUF2768 PF10966.3 AIF82800.1 - 0.79 9.9 3.8 0.22 11.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) DUF4231 PF14015.1 AIF82800.1 - 5.2 7.1 5.3 11 6.0 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Cupredoxin_1 PF13473.1 AIF82801.1 - 1.9e-11 43.7 0.1 3.3e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Cupredoxin-like domain SoxE PF06525.6 AIF82801.1 - 0.0059 15.9 3.1 0.0091 15.2 2.1 1.3 1 1 0 1 1 1 1 Sulfocyanin (SoxE) Copper-bind PF00127.15 AIF82801.1 - 0.015 15.5 1.0 0.033 14.4 0.2 1.9 1 1 1 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.10 AIF82801.1 - 0.069 12.8 0.3 0.18 11.5 0.2 1.8 1 1 0 1 1 1 0 Multicopper oxidase R_equi_Vir PF05526.6 AIF82801.1 - 0.27 10.8 4.1 0.42 10.2 2.7 1.5 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein SSP160 PF06933.6 AIF82801.1 - 0.93 7.3 17.4 1.1 7.1 12.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 AIF82801.1 - 2.5 5.7 6.7 3 5.4 4.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein eIF-1a PF01176.14 AIF82802.1 - 8.2e-22 76.4 1.1 9.9e-22 76.1 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.14 AIF82802.1 - 0.0049 16.5 1.0 0.021 14.4 0.2 2.1 2 1 0 2 2 2 1 Myosin N-terminal SH3-like domain DUF1314 PF07013.6 AIF82802.1 - 0.062 12.6 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) AmoC PF04896.7 AIF82803.1 - 3.2e-16 59.1 5.1 3.5e-16 58.9 3.5 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C OAD_gamma PF04277.8 AIF82803.1 - 0.44 10.9 1.8 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain NMN_transporter PF04973.7 AIF82803.1 - 1.3 8.3 8.3 1.3 8.4 4.7 1.7 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter HicB PF05534.7 AIF82804.1 - 0.0015 18.0 0.5 0.0031 17.0 0.2 1.7 2 0 0 2 2 2 1 HicB family RHH_1 PF01402.16 AIF82804.1 - 0.063 13.1 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family FUN14 PF04930.10 AIF82805.1 - 1.3e-18 67.0 8.0 1.5e-18 66.8 5.5 1.0 1 0 0 1 1 1 1 FUN14 family Holin_LLH PF09682.5 AIF82805.1 - 0.11 12.6 1.5 0.16 12.1 0.6 1.6 1 1 1 2 2 2 0 Phage holin protein (Holin_LLH) SPC12 PF06645.8 AIF82805.1 - 1.2 9.0 6.9 0.54 10.0 3.0 1.9 1 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Vma12 PF11712.3 AIF82805.1 - 3.7 7.2 4.8 6.5 6.4 2.3 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Yip1 PF04893.12 AIF82806.1 - 0.33 10.4 26.0 0.48 9.9 18.0 1.3 1 0 0 1 1 1 0 Yip1 domain HTH_11 PF08279.7 AIF82807.1 - 4.5e-07 29.4 0.1 7.6e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 HTH domain B12-binding_2 PF02607.12 AIF82807.1 - 1.7e-06 27.9 0.0 4.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain HTH_24 PF13412.1 AIF82807.1 - 4.7e-06 25.8 0.0 8.4e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF2250 PF10007.4 AIF82807.1 - 0.00038 20.3 0.1 0.00071 19.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) MarR PF01047.17 AIF82807.1 - 0.0022 17.6 0.1 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 MarR family GntR PF00392.16 AIF82807.1 - 0.0096 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_5 PF01022.15 AIF82807.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RepL PF05732.6 AIF82807.1 - 0.036 13.2 0.3 0.066 12.4 0.2 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_IclR PF09339.5 AIF82807.1 - 0.047 13.2 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_45 PF14947.1 AIF82807.1 - 0.05 13.4 0.2 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix Mnd1 PF03962.10 AIF82807.1 - 0.083 12.5 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Mnd1 family TrmB PF01978.14 AIF82807.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ACT_7 PF13840.1 AIF82808.1 - 4.7e-06 26.0 0.0 1.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain ECH_C PF13766.1 AIF82808.1 - 0.02 15.0 0.2 0.091 12.9 0.0 2.2 2 1 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region AHS1 PF02682.11 AIF82808.1 - 0.046 13.1 0.9 0.44 9.9 0.2 2.0 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 Arginosuc_synth PF00764.14 AIF82809.1 - 1.4e-162 541.1 0.5 1.6e-162 540.9 0.3 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AIF82809.1 - 0.00064 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AIF82809.1 - 0.016 14.5 0.1 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AIF82809.1 - 0.043 12.3 0.0 0.083 11.4 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase DUF1471 PF07338.8 AIF82809.1 - 0.082 12.5 0.1 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) zinc_ribbon_5 PF13719.1 AIF82810.1 - 5.7e-05 22.6 1.4 0.0091 15.5 1.4 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIF82810.1 - 7.8e-05 22.2 1.6 0.0072 15.9 1.5 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF82810.1 - 0.00024 20.1 0.7 0.29 10.4 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain YhfH PF14149.1 AIF82810.1 - 0.0019 17.9 3.6 0.029 14.1 0.5 2.1 2 0 0 2 2 2 1 YhfH-like protein zf-RING_3 PF14369.1 AIF82810.1 - 0.0033 17.3 0.9 0.0061 16.5 0.6 1.4 1 1 0 1 1 1 1 zinc-finger DNA_RNApol_7kD PF03604.8 AIF82810.1 - 0.0038 16.6 4.4 0.067 12.6 2.7 2.6 1 1 2 3 3 3 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 AIF82810.1 - 0.0071 16.1 0.6 0.011 15.5 0.4 1.4 1 1 0 1 1 1 1 Double zinc ribbon PAAR_motif PF05488.8 AIF82810.1 - 0.0099 15.8 0.2 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 PAAR motif zf-IS66 PF13005.2 AIF82810.1 - 0.01 15.7 4.3 0.084 12.8 0.1 2.3 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 OrfB_Zn_ribbon PF07282.6 AIF82810.1 - 0.011 15.3 0.2 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1272 PF06906.6 AIF82810.1 - 0.013 15.3 4.1 1.2 9.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-C4_Topoisom PF01396.14 AIF82810.1 - 0.017 14.5 2.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.5 AIF82810.1 - 0.017 15.0 3.4 0.14 12.1 2.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain HypA PF01155.14 AIF82810.1 - 0.019 14.6 0.4 0.02 14.5 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 AIF82810.1 - 0.019 14.6 5.2 0.14 11.9 3.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 UPF0547 PF10571.4 AIF82810.1 - 0.023 14.3 1.1 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.7 AIF82810.1 - 0.05 13.3 0.1 0.098 12.4 0.1 1.5 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.1 AIF82810.1 - 0.064 12.7 2.8 0.53 9.8 1.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-HYPF PF07503.7 AIF82810.1 - 0.069 12.5 2.2 0.99 8.8 1.5 2.0 1 1 0 1 1 1 0 HypF finger zf-CSL PF05207.8 AIF82810.1 - 0.073 12.5 1.9 0.22 11.0 1.3 1.7 1 1 1 2 2 2 0 CSL zinc finger CpXC PF14353.1 AIF82810.1 - 0.077 12.9 0.2 4.2 7.3 0.0 2.1 2 0 0 2 2 2 0 CpXC protein A2L_zn_ribbon PF08792.5 AIF82810.1 - 0.099 12.1 1.9 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Nudix_N_2 PF14803.1 AIF82810.1 - 0.11 12.1 0.9 9 6.0 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.7 AIF82810.1 - 0.14 11.4 2.7 0.31 10.4 1.9 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding DUF983 PF06170.7 AIF82810.1 - 0.17 12.0 1.3 7.1 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Lar_restr_allev PF14354.1 AIF82810.1 - 0.23 11.8 3.9 7.5 6.9 2.7 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF3797 PF12677.2 AIF82810.1 - 0.23 11.0 2.8 2.8 7.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-trcl PF13451.1 AIF82810.1 - 0.38 10.4 2.4 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain DUF164 PF02591.10 AIF82810.1 - 1.9 8.4 3.9 9.9 6.0 2.7 2.0 1 1 0 1 1 1 0 Putative zinc ribbon domain zf-dskA_traR PF01258.12 AIF82810.1 - 2.1 8.1 7.8 3.1 7.6 0.8 2.2 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-TFIIB PF13453.1 AIF82810.1 - 5.5 6.2 6.9 1.7 7.9 0.4 2.2 2 1 1 3 3 3 0 Transcription factor zinc-finger RimK PF08443.6 AIF82811.1 - 5.2e-48 163.0 0.0 7e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 AIF82811.1 - 3e-14 52.5 0.0 4.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 AIF82811.1 - 6.9e-14 51.9 0.0 9.9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AIF82811.1 - 1e-10 41.7 0.0 2.5e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIF82811.1 - 2.3e-09 36.4 0.0 5.3e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AIF82811.1 - 5.4e-07 29.1 0.0 1.1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AIF82811.1 - 2.7e-05 23.5 0.0 5e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_YheCD PF14398.1 AIF82811.1 - 0.00015 20.7 0.0 0.0034 16.2 0.0 2.2 1 1 1 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_5 PF13549.1 AIF82811.1 - 0.0016 17.7 0.0 0.0038 16.4 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AIF82811.1 - 0.037 13.4 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.5 AIF82811.1 - 0.055 12.8 0.0 0.19 11.1 0.0 1.8 1 1 1 2 2 2 0 ATP-grasp domain Semialdhyde_dh PF01118.19 AIF82812.1 - 1.4e-37 128.7 0.0 2.7e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 AIF82812.1 - 1.3e-22 80.5 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain F420_oxidored PF03807.12 AIF82812.1 - 0.00018 21.8 0.0 0.00044 20.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 AIF82812.1 - 0.00026 20.9 0.1 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 AIF82812.1 - 0.0013 19.2 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.1 AIF82812.1 - 0.0034 17.4 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 AIF82812.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AA_kinase PF00696.23 AIF82813.1 - 9.9e-34 116.9 5.1 1.1e-33 116.7 3.5 1.0 1 0 0 1 1 1 1 Amino acid kinase family Aminotran_3 PF00202.16 AIF82814.1 - 3.4e-105 351.6 0.1 4.5e-105 351.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AIF82814.1 - 0.00014 20.9 0.0 0.00048 19.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AIF82814.1 - 0.0012 17.7 0.0 0.0017 17.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Microvir_J PF04726.8 AIF82814.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Microvirus J protein HTH_AsnC-type PF13404.1 AIF82815.1 - 4.3e-16 58.1 0.8 1.1e-15 56.9 0.2 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AIF82815.1 - 5.3e-15 54.5 0.5 1.4e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 AIF82815.1 - 1.9e-11 43.4 0.3 3.1e-11 42.8 0.2 1.3 1 0 0 1 1 1 1 AsnC family HTH_11 PF08279.7 AIF82815.1 - 5.8e-05 22.6 0.2 0.00014 21.4 0.2 1.7 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.15 AIF82815.1 - 8.5e-05 22.1 0.0 0.00073 19.1 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.5 AIF82815.1 - 0.00084 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.2 AIF82815.1 - 0.0012 18.5 0.3 0.0034 17.0 0.0 1.8 1 1 1 2 2 2 1 MarR family TrmB PF01978.14 AIF82815.1 - 0.0018 17.9 0.2 0.0074 15.9 0.1 2.0 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.1 AIF82815.1 - 0.0068 15.5 0.1 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 NapD PF03927.8 AIF82815.1 - 0.012 15.4 2.3 0.052 13.3 0.6 2.1 2 0 0 2 2 2 0 NapD protein HTH_20 PF12840.2 AIF82815.1 - 0.024 14.4 0.0 0.063 13.0 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.17 AIF82815.1 - 0.031 13.9 1.9 0.042 13.5 0.0 2.1 3 0 0 3 3 3 0 MarR family B-block_TFIIIC PF04182.7 AIF82815.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC FaeA PF04703.7 AIF82815.1 - 0.054 13.6 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 FaeA-like protein HTH_6 PF01418.12 AIF82815.1 - 0.071 12.8 0.1 0.071 12.8 0.1 2.4 2 1 0 3 3 2 0 Helix-turn-helix domain, rpiR family Sigma70_r4 PF04545.11 AIF82815.1 - 0.073 12.3 0.1 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 GYD PF08734.6 AIF82815.1 - 0.078 12.7 0.1 0.36 10.5 0.0 2.0 1 1 1 2 2 2 0 GYD domain Rrf2 PF02082.15 AIF82815.1 - 0.083 13.0 0.2 0.52 10.4 0.0 2.1 1 1 1 2 2 2 0 Transcriptional regulator HTH_12 PF08461.5 AIF82815.1 - 0.088 12.5 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Mga PF05043.8 AIF82815.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_DeoR PF08220.7 AIF82815.1 - 0.096 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_34 PF13601.1 AIF82815.1 - 0.098 12.6 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_Mga PF08280.6 AIF82815.1 - 0.1 12.3 0.1 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_27 PF13463.1 AIF82815.1 - 0.12 12.7 0.1 0.33 11.3 0.0 1.8 1 1 0 1 1 1 0 Winged helix DNA-binding domain Phage_terminase PF10668.4 AIF82815.1 - 0.15 11.8 0.1 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit DUF3487 PF11990.3 AIF82816.1 - 4.5 6.6 7.5 3.4 7.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) DUF2651 PF10852.3 AIF82816.1 - 8.4 6.8 10.2 0.4 11.0 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2651) Methyltransf_11 PF08241.7 AIF82818.1 - 2.1e-14 53.7 0.0 3.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82818.1 - 2.8e-08 33.6 0.0 3.8e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIF82818.1 - 9.8e-05 21.5 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 AIF82818.1 - 0.00015 21.3 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF82818.1 - 0.0003 20.1 0.1 0.0019 17.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AIF82818.1 - 0.00031 21.1 0.0 0.00053 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF82818.1 - 0.0035 17.6 0.0 0.0064 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AIF82818.1 - 0.0071 15.8 0.1 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 AIF82818.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Nitroreductase PF00881.19 AIF82820.1 - 1.3e-28 99.8 0.0 1.7e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family zf-CDGSH PF09360.5 AIF82821.1 - 3e-31 106.9 3.5 3.4e-17 61.9 0.1 2.7 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Fer4_19 PF06902.6 AIF82821.1 - 4.7e-07 29.5 0.2 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Divergent 4Fe-4S mono-cluster Abhydrolase_3 PF07859.8 AIF82822.1 - 1.7e-72 243.3 0.0 2.3e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIF82822.1 - 2.5e-06 27.2 0.7 2.4e-05 24.1 0.2 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 AIF82822.1 - 7.8e-05 21.5 1.5 0.00058 18.6 1.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 AIF82822.1 - 0.00049 19.3 0.2 0.0022 17.2 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 AIF82822.1 - 0.0007 18.5 0.0 0.00099 18.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2424 PF10340.4 AIF82822.1 - 0.00096 17.8 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 AIF82822.1 - 0.0015 17.3 0.0 0.0022 16.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.7 AIF82822.1 - 0.0059 15.1 0.0 0.027 12.9 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase PF00756.15 AIF82822.1 - 0.013 14.9 0.3 0.44 9.9 0.2 2.1 1 1 0 1 1 1 0 Putative esterase Wzt_C PF14524.1 AIF82823.1 - 0.11 12.1 0.1 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain Ribosomal_L15e PF00827.12 AIF82825.1 - 2.8e-49 167.2 3.3 3.3e-49 167.0 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 OrfB_IS605 PF01385.14 AIF82827.1 - 2.5e-25 89.2 3.3 3.5e-25 88.7 2.3 1.2 1 0 0 1 1 1 1 Probable transposase OrfB_Zn_ribbon PF07282.6 AIF82827.1 - 2.1e-18 65.7 0.6 4.4e-18 64.6 0.4 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.3 AIF82827.1 - 1.2e-09 37.3 2.7 3.8e-09 35.7 1.8 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain PP28 PF10252.4 AIF82827.1 - 0.017 15.1 0.6 0.04 13.9 0.5 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 C1_1 PF00130.17 AIF82827.1 - 0.035 13.8 0.9 0.082 12.6 0.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 AIF82827.1 - 0.055 13.1 0.3 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 AIF82827.1 - 0.088 12.1 1.3 7.5 5.9 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding 2-Hacid_dh_C PF02826.14 AIF82828.1 - 6.3e-65 217.6 0.0 2.7e-64 215.5 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AIF82828.1 - 4.2e-30 103.9 0.3 4.8e-30 103.7 0.2 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AIF82828.1 - 6.8e-07 29.2 0.3 5.5e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AIF82828.1 - 0.079 13.3 2.4 5.8 7.4 0.2 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF1326 PF07040.6 AIF82830.1 - 7.2e-57 192.1 0.1 8.2e-57 191.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1326) PGC7_Stella PF15549.1 AIF82831.1 - 0.34 10.8 4.7 0.44 10.5 3.2 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain DUF1326 PF07040.6 AIF82832.1 - 7.5e-48 162.7 0.0 8.6e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1326) DUF2182 PF09948.4 AIF82833.1 - 3.5e-45 154.2 21.6 3.5e-45 154.2 15.0 2.9 2 1 0 2 2 2 1 Predicted metal-binding integral membrane protein (DUF2182) zf-DHHC PF01529.15 AIF82833.1 - 0.082 12.2 8.3 0.25 10.7 0.3 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4231 PF14015.1 AIF82833.1 - 3.3 7.7 7.1 1.6 8.6 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) EIIC-GAT PF03611.9 AIF82835.1 - 0.15 10.8 0.3 0.16 10.7 0.2 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component Sensor_TM1 PF13755.1 AIF82836.1 - 0.078 12.4 1.3 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain ABC_cobalt PF09819.4 AIF82836.1 - 1.4 8.8 15.3 2.3 8.1 10.6 1.4 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component DUF2964 PF11177.3 AIF82836.1 - 2.6 8.0 12.6 1.3 8.9 2.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2964) Lyase_1 PF00206.15 AIF82837.1 - 9e-91 304.2 0.3 1.2e-90 303.9 0.2 1.2 1 0 0 1 1 1 1 Lyase Acetyltransf_3 PF13302.1 AIF82837.1 - 2.1e-31 108.9 0.0 3.5e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FumaraseC_C PF10415.4 AIF82837.1 - 2.9e-19 68.8 0.6 9e-19 67.2 0.4 2.0 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_4 PF13420.1 AIF82837.1 - 7.5e-17 61.6 0.0 2.4e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AIF82837.1 - 5.3e-09 35.9 0.1 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 AIF82837.1 - 0.0042 16.9 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF488 PF04343.8 AIF82839.1 - 3.8e-28 98.2 0.4 4.3e-28 98.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF488 UTP15_C PF09384.5 AIF82839.1 - 0.033 13.8 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 UTP15 C terminal CARD PF00619.16 AIF82839.1 - 0.11 12.2 0.1 1.5 8.6 0.1 2.1 2 0 0 2 2 2 0 Caspase recruitment domain ADH_N PF08240.7 AIF82840.1 - 1e-33 115.3 0.3 1.7e-33 114.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIF82840.1 - 5.3e-28 97.1 0.5 5.3e-28 97.1 0.4 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIF82840.1 - 3.8e-11 43.9 0.7 1.1e-10 42.4 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 AIF82840.1 - 0.014 15.7 0.6 0.59 10.5 0.6 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AIF82840.1 - 0.024 14.2 1.4 0.044 13.3 0.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 AIF82840.1 - 0.029 14.3 0.7 0.05 13.5 0.2 1.6 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 AIF82840.1 - 0.03 13.4 0.4 0.063 12.4 0.2 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 AIF82840.1 - 0.089 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase 3HCDH_N PF02737.13 AIF82840.1 - 0.15 11.6 1.1 0.28 10.8 0.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 AIF82841.1 - 6.6e-41 140.6 0.0 8.2e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIF82841.1 - 6e-25 88.1 0.2 3.3e-23 82.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIF82841.1 - 8.1e-22 77.5 0.0 1.7e-21 76.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 AIF82841.1 - 1.5e-06 26.8 0.0 1.4e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 AIF82841.1 - 2.6e-06 27.1 0.0 5.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 AIF82841.1 - 3.8e-05 22.6 0.0 9.7e-05 21.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF676 PF05057.9 AIF82841.1 - 9e-05 21.8 0.0 0.00035 19.9 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 AIF82841.1 - 0.00018 20.4 0.0 0.0065 15.3 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 AIF82841.1 - 0.00072 19.0 0.2 0.52 9.7 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 AIF82841.1 - 0.0011 18.2 0.0 0.07 12.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AIF82841.1 - 0.0028 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 AIF82841.1 - 0.0037 17.0 1.2 0.011 15.5 0.1 2.1 2 1 0 2 2 1 1 Uncharacterised protein family (UPF0227) DUF2305 PF10230.4 AIF82841.1 - 0.0039 16.6 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 AIF82841.1 - 0.0043 16.5 0.0 0.063 12.7 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 AIF82841.1 - 0.0047 17.1 0.0 0.0067 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.13 AIF82841.1 - 0.0061 15.8 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.8 AIF82841.1 - 0.0087 15.6 0.5 0.066 12.7 0.3 2.3 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 AIF82841.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.6 AIF82841.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.6 AIF82841.1 - 0.02 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydro_lipase PF04083.11 AIF82841.1 - 0.023 14.0 0.0 0.072 12.4 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_4 PF08386.5 AIF82841.1 - 0.032 14.1 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Peptidase_S15 PF02129.13 AIF82841.1 - 0.04 13.3 0.0 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 AIF82841.1 - 0.049 13.2 0.0 0.24 11.0 0.0 2.1 3 0 0 3 3 3 0 Lipase (class 3) Ser_hydrolase PF06821.8 AIF82841.1 - 0.14 11.7 0.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Aldedh PF00171.17 AIF82842.1 - 1.3e-148 495.1 0.3 1.5e-148 494.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AIF82842.1 - 0.0026 16.5 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) ALAD PF00490.16 AIF82843.1 - 3.9e-115 384.2 0.6 4.5e-115 383.9 0.4 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CorA PF01544.13 AIF82844.1 - 6.5e-58 196.0 0.9 7.4e-58 195.8 0.6 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Atg14 PF10186.4 AIF82844.1 - 0.047 12.6 0.1 0.059 12.2 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4201 PF13870.1 AIF82844.1 - 0.072 12.5 0.9 0.11 11.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) MAD PF05557.8 AIF82844.1 - 0.19 9.8 1.8 0.25 9.4 1.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein SnoaL_2 PF12680.2 AIF82847.1 - 4.5e-12 46.2 0.0 4.9e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AIF82847.1 - 2e-08 34.4 0.0 2.2e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 AIF82847.1 - 1.7e-05 24.4 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 AIF82847.1 - 2.5e-05 24.2 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 AIF82847.1 - 0.004 17.5 0.0 0.0045 17.3 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 AIF82847.1 - 0.011 15.5 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Lumazine_bd PF12870.2 AIF82847.1 - 0.028 14.4 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Lumazine-binding domain LEH PF07858.7 AIF82847.1 - 0.043 13.8 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain eIF-5a PF01287.15 AIF82848.1 - 2.6e-11 43.2 2.2 3.5e-11 42.8 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 AIF82848.1 - 1.6e-08 34.2 0.1 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 AIF82848.1 - 0.015 14.9 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain KOW PF00467.24 AIF82848.1 - 0.034 13.8 0.7 0.097 12.4 0.0 2.2 3 0 0 3 3 3 0 KOW motif BPD_transp_1 PF00528.17 AIF82849.1 - 5.3e-26 91.2 10.2 5.3e-26 91.2 7.0 1.8 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.2 AIF82849.1 - 0.014 14.7 0.4 0.05 12.9 0.0 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1634 PF07843.6 AIF82849.1 - 1.4 8.5 8.9 0.23 11.1 1.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) BPD_transp_1 PF00528.17 AIF82850.1 - 1.4e-36 125.7 13.9 1.4e-36 125.7 9.7 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.16 AIF82850.1 - 8.9 6.1 23.3 0.12 12.1 2.3 3.4 3 1 0 3 3 3 0 FtsX-like permease family SBP_bac_5 PF00496.17 AIF82851.1 - 1.9e-17 63.1 1.0 1.9e-17 63.1 0.7 2.6 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle ABC_tran PF00005.22 AIF82852.1 - 1.2e-31 109.7 0.0 1.6e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 AIF82852.1 - 1.1e-06 28.8 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region Zeta_toxin PF06414.7 AIF82852.1 - 4.7e-05 22.5 0.0 0.00011 21.4 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 AIF82852.1 - 5.6e-05 23.3 0.1 0.00029 20.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 AIF82852.1 - 0.00013 22.0 0.0 0.059 13.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 AIF82852.1 - 0.00019 21.4 0.2 0.00039 20.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 AIF82852.1 - 0.0015 18.1 0.1 0.0027 17.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 AIF82852.1 - 0.0016 18.1 0.0 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 AIF82852.1 - 0.0023 17.3 0.1 0.0049 16.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 AIF82852.1 - 0.0027 18.0 0.0 0.0048 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIF82852.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIF82852.1 - 0.0093 15.6 0.1 0.048 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 AIF82852.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 AIF82852.1 - 0.02 14.9 0.0 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 AIF82852.1 - 0.021 15.0 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AIF82852.1 - 0.021 15.6 0.1 0.048 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 AIF82852.1 - 0.032 13.1 0.1 0.073 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.1 AIF82852.1 - 0.034 14.0 0.1 0.053 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain GvpD PF07088.6 AIF82852.1 - 0.045 12.0 0.0 0.063 11.5 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.21 AIF82852.1 - 0.049 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.15 AIF82852.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DEAD PF00270.24 AIF82852.1 - 0.1 12.0 0.1 0.25 10.7 0.1 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase PRK PF00485.13 AIF82852.1 - 0.12 11.9 0.2 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 AIF82852.1 - 0.13 11.8 0.3 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AIF82852.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AIF82852.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 AIF82852.1 - 0.15 11.4 0.1 1.2 8.5 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain ATP_bind_4 PF01902.12 AIF82853.1 - 1.2e-62 211.1 0.0 1.4e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 ATP-binding region QueC PF06508.8 AIF82853.1 - 0.029 13.6 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC SRP54 PF00448.17 AIF82854.1 - 2.5e-70 235.9 0.2 4e-70 235.2 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AIF82854.1 - 4.9e-27 94.2 9.6 3.8e-26 91.3 4.4 2.5 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 AIF82854.1 - 2.3e-14 53.2 0.4 6.7e-14 51.7 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 AIF82854.1 - 1.8e-09 37.2 0.1 7.9e-09 35.1 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AIF82854.1 - 2.7e-06 27.1 0.1 6.4e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AIF82854.1 - 8.9e-06 25.2 0.3 5.9e-05 22.5 0.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AIF82854.1 - 6.5e-05 21.8 1.6 8.2e-05 21.5 0.1 1.8 2 1 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 AIF82854.1 - 9.8e-05 22.5 0.1 0.00045 20.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 AIF82854.1 - 0.00051 19.7 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 AIF82854.1 - 0.00061 19.8 0.2 0.002 18.1 0.1 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.1 AIF82854.1 - 0.00077 19.3 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 AIF82854.1 - 0.0012 18.0 0.3 0.067 12.2 0.2 2.4 1 1 0 1 1 1 1 ATPase MipZ AAA PF00004.24 AIF82854.1 - 0.0014 18.8 0.0 0.011 15.8 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AIF82854.1 - 0.002 17.5 0.1 0.0046 16.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIF82854.1 - 0.0024 18.6 0.1 0.0073 17.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIF82854.1 - 0.0033 17.1 0.2 0.009 15.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Thymidylate_kin PF02223.12 AIF82854.1 - 0.0039 16.5 0.1 0.0086 15.4 0.1 1.6 1 0 0 1 1 1 1 Thymidylate kinase AAA_10 PF12846.2 AIF82854.1 - 0.0041 16.5 0.2 0.0083 15.5 0.2 1.8 1 1 0 1 1 1 1 AAA-like domain Mur_ligase_M PF08245.7 AIF82854.1 - 0.0044 17.0 0.1 0.011 15.8 0.1 1.7 1 1 0 1 1 1 1 Mur ligase middle domain KTI12 PF08433.5 AIF82854.1 - 0.0064 15.7 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArsA_ATPase PF02374.10 AIF82854.1 - 0.0071 15.4 2.1 0.036 13.1 0.1 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_18 PF13238.1 AIF82854.1 - 0.0091 16.3 0.2 0.03 14.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 AIF82854.1 - 0.012 15.1 0.1 5.2 6.5 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 AIF82854.1 - 0.014 15.0 0.4 0.047 13.4 0.3 2.0 1 1 0 1 1 1 0 NTPase AAA_30 PF13604.1 AIF82854.1 - 0.014 14.9 0.9 0.043 13.3 0.2 2.2 2 1 0 2 2 1 0 AAA domain AAA_26 PF13500.1 AIF82854.1 - 0.015 14.9 0.1 0.13 11.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 AIF82854.1 - 0.016 14.2 0.0 0.041 12.9 0.0 1.7 1 0 0 1 1 1 0 6-phosphofructo-2-kinase LpxK PF02606.9 AIF82854.1 - 0.019 13.9 0.4 0.038 12.9 0.3 1.4 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_5 PF07728.9 AIF82854.1 - 0.035 13.8 0.5 0.19 11.4 0.1 2.4 2 1 1 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 AIF82854.1 - 0.039 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LytR_C PF13399.1 AIF82854.1 - 0.051 13.9 0.3 0.33 11.3 0.0 2.5 3 0 0 3 3 2 0 LytR cell envelope-related transcriptional attenuator AAA_28 PF13521.1 AIF82854.1 - 0.06 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AIF82854.1 - 0.088 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Arch_fla_DE PF04659.8 AIF82854.1 - 0.12 12.2 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal flagella protein KduI PF04962.7 AIF82854.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family THUMP PF02926.12 AIF82855.1 - 0.00016 21.5 0.0 0.00086 19.2 0.0 2.0 2 0 0 2 2 2 1 THUMP domain C5-epim_C PF06662.8 AIF82856.1 - 1.6e-29 102.5 2.2 2.4e-29 101.9 1.5 1.2 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 AIF82856.1 - 0.0042 16.1 4.6 0.1 11.6 0.5 2.5 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 SP_C-Propep PF08999.5 AIF82857.1 - 0.024 14.1 4.3 0.027 13.9 3.0 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF843 PF05814.6 AIF82857.1 - 0.93 9.3 4.0 1.4 8.7 2.7 1.4 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) m04gp34like PF12216.3 AIF82857.1 - 1 8.6 3.5 1.1 8.5 2.4 1.1 1 0 0 1 1 1 0 Immune evasion protein DUF3149 PF11346.3 AIF82857.1 - 5.2 6.7 7.0 0.32 10.6 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF1510 PF07423.6 AIF82858.1 - 6.3e-06 25.7 4.0 8.3e-06 25.3 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) NTP_transf_2 PF01909.18 AIF82860.1 - 6.9e-07 29.5 0.6 1.6e-06 28.3 0.4 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain Kdo PF06293.9 AIF82860.1 - 0.0049 15.9 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIF82860.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ribosomal_S27 PF01599.14 AIF82861.1 - 9.7e-22 76.5 7.4 1.3e-21 76.1 5.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S27a GCC2_GCC3 PF07699.8 AIF82861.1 - 0.0023 17.4 2.2 0.0029 17.1 1.5 1.2 1 0 0 1 1 1 1 GCC2 and GCC3 DUF1451 PF07295.6 AIF82861.1 - 0.0041 16.8 1.1 0.0043 16.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1451) DZR PF12773.2 AIF82861.1 - 0.0042 16.8 1.2 0.0059 16.4 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon Ribosomal_L37e PF01907.14 AIF82861.1 - 0.0069 16.1 3.6 0.009 15.7 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e DUF2082 PF09855.4 AIF82861.1 - 0.012 15.4 6.4 0.015 15.1 0.2 2.4 2 1 1 3 3 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) NCD3G PF07562.9 AIF82861.1 - 0.013 15.1 0.6 0.018 14.7 0.4 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR IBR PF01485.16 AIF82861.1 - 0.015 15.1 0.7 0.02 14.7 0.5 1.2 1 0 0 1 1 1 0 IBR domain GFA PF04828.9 AIF82861.1 - 0.016 15.1 2.2 0.22 11.4 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 AIF82861.1 - 0.021 14.4 1.2 0.14 11.8 0.9 2.0 1 1 0 1 1 1 0 Nudix N-terminal A2L_zn_ribbon PF08792.5 AIF82861.1 - 0.024 14.1 2.4 0.041 13.3 1.6 1.4 1 1 0 1 1 1 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AIF82861.1 - 0.026 14.1 1.4 0.034 13.8 1.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2387 PF09526.5 AIF82861.1 - 0.028 14.3 1.7 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) HypA PF01155.14 AIF82861.1 - 0.036 13.7 0.5 0.039 13.6 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 AIF82861.1 - 0.045 13.5 4.4 0.38 10.5 3.1 2.0 1 1 2 3 3 3 0 Transposase zinc-ribbon domain C1_1 PF00130.17 AIF82861.1 - 0.048 13.3 1.7 0.067 12.9 1.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.8 AIF82861.1 - 0.075 12.5 1.6 0.14 11.6 1.1 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.1 AIF82861.1 - 0.14 11.6 3.9 3 7.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1936 PF09151.5 AIF82861.1 - 0.24 10.9 1.8 7.1 6.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) zf-C2H2 PF00096.21 AIF82861.1 - 0.69 10.3 2.8 4.5 7.8 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.1 AIF82861.1 - 1.1 8.5 5.4 9 5.6 3.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 AIF82861.1 - 1.1 9.6 3.4 3.8 7.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain FeS PF04060.8 AIF82861.1 - 4 7.1 7.5 0.25 10.9 0.5 2.2 2 0 0 2 2 2 0 Putative Fe-S cluster Ribosomal_S24e PF01282.14 AIF82862.1 - 7e-08 32.1 0.3 1e-07 31.6 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e UbiD PF01977.11 AIF82864.1 - 8.9e-154 511.8 0.8 1e-153 511.6 0.5 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Acetyltransf_1 PF00583.19 AIF82865.1 - 4.4e-09 36.2 0.0 4.3e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AIF82865.1 - 5e-05 23.4 0.0 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AIF82865.1 - 8e-05 22.7 0.0 0.00048 20.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIF82865.1 - 0.0045 16.8 0.0 0.035 13.9 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain CsoS2_M PF12288.3 AIF82865.1 - 0.096 11.8 0.3 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region Radical_SAM PF04055.16 AIF82866.1 - 1e-17 64.8 0.1 2e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM PF04055.16 AIF82867.1 - 4.8e-16 59.3 0.1 9.1e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UbiA PF01040.13 AIF82868.1 - 0.0038 16.4 0.4 0.0038 16.4 0.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4231 PF14015.1 AIF82868.1 - 0.04 13.9 1.4 0.049 13.6 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Sensor_TM1 PF13755.1 AIF82868.1 - 0.14 11.6 3.2 0.17 11.4 2.2 1.2 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain DUF4407 PF14362.1 AIF82868.1 - 1.9 7.3 6.0 2.4 7.0 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF454 PF04304.8 AIF82868.1 - 1.9 8.5 6.2 2.4 8.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF454) DUF3976 PF13121.1 AIF82868.1 - 4.9 7.0 5.5 0.74 9.7 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) Amidase PF01425.16 AIF82869.1 - 4.1e-130 434.5 0.0 4.7e-130 434.3 0.0 1.0 1 0 0 1 1 1 1 Amidase AIRC PF00731.15 AIF82870.1 - 8.2e-48 161.4 0.3 9.6e-48 161.2 0.2 1.0 1 0 0 1 1 1 1 AIR carboxylase Hydrolase_3 PF08282.7 AIF82870.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Transp_cyt_pur PF02133.10 AIF82871.1 - 9.2e-19 67.3 47.0 1.3e-18 66.8 32.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Isochorismatase PF00857.15 AIF82872.1 - 1.4e-31 109.7 0.0 2.5e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family CitMHS PF03600.11 AIF82873.1 - 2.3e-53 181.0 33.9 2.3e-53 181.0 23.5 2.4 1 1 1 2 2 2 1 Citrate transporter ArsB PF02040.10 AIF82873.1 - 3.2e-24 85.6 35.7 3.2e-24 85.6 24.7 1.4 1 1 1 2 2 2 2 Arsenical pump membrane protein Na_sulph_symp PF00939.14 AIF82873.1 - 6.7e-13 48.3 39.1 1.9e-07 30.3 10.3 2.2 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region DUF3087 PF11286.3 AIF82873.1 - 3.8 6.7 6.8 1.6 7.9 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) FAA_hydrolase PF01557.13 AIF82874.1 - 3.4e-68 229.3 0.0 1.1e-67 227.7 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family SpoA PF01052.15 AIF82874.1 - 0.013 15.0 0.1 0.031 13.8 0.1 1.6 1 1 0 1 1 1 0 Surface presentation of antigens (SPOA) VitK2_biosynth PF02621.9 AIF82877.1 - 1.2e-67 227.8 0.0 1.3e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis GTP_EFTU PF00009.22 AIF82878.1 - 4.2e-50 169.8 0.0 7.8e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AIF82878.1 - 1.5e-25 89.0 0.1 6.4e-25 87.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 AIF82878.1 - 4e-19 68.2 0.3 7.6e-19 67.3 0.2 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AIF82878.1 - 8.3e-19 67.2 0.0 1.9e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AIF82878.1 - 1.5e-11 44.2 0.1 4.9e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF4397 PF14344.1 AIF82879.1 - 0.016 15.5 0.4 0.056 13.7 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4397) DUF4536 PF15055.1 AIF82879.1 - 0.08 13.0 0.4 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) DUF3188 PF11384.3 AIF82879.1 - 0.16 11.5 6.7 0.5 9.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) SnoaL_2 PF12680.2 AIF82880.1 - 4.2e-10 39.9 0.0 4.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AIF82880.1 - 2.1e-08 34.3 0.0 2.3e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 AIF82880.1 - 0.00013 21.5 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 AIF82880.1 - 0.0086 16.1 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain ABM PF03992.11 AIF82882.1 - 1.9e-07 31.0 0.1 3.2e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase BNR PF02012.15 AIF82883.1 - 6 7.1 18.2 9.7 6.4 0.0 7.1 7 0 0 7 7 7 0 BNR/Asp-box repeat DUF1351 PF07083.6 AIF82886.1 - 0.016 14.8 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Inhibitor_I67 PF11405.3 AIF82887.1 - 0.059 13.4 0.3 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Bromelain inhibitor VI Thioredoxin_8 PF13905.1 AIF82887.1 - 0.071 13.2 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like FlaG PF03646.10 AIF82888.1 - 0.085 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 FlaG protein GNVR PF13807.1 AIF82888.1 - 0.096 12.4 0.4 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF3367 PF11847.3 AIF82889.1 - 0.027 12.4 0.6 0.043 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) SseB PF07179.7 AIF82890.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 SseB protein N-terminal domain adh_short PF00106.20 AIF82891.1 - 1.2e-25 90.3 0.6 5.5e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIF82891.1 - 5.8e-21 75.3 0.2 7.3e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF82891.1 - 1.2e-09 38.0 2.0 5.8e-09 35.8 0.0 2.1 1 1 0 2 2 2 1 KR domain DUF1776 PF08643.5 AIF82891.1 - 0.00012 21.3 0.0 0.0019 17.3 0.0 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 AIF82891.1 - 0.01 15.8 1.0 0.043 13.8 0.7 1.9 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AIF82891.1 - 0.024 14.4 0.2 0.07 12.9 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PMSR PF01625.16 AIF82897.1 - 1.2e-64 216.8 2.4 1.4e-64 216.6 1.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Rrf2 PF02082.15 AIF82898.1 - 0.08 13.0 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_45 PF14947.1 AIF82898.1 - 0.088 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix HAD PF12710.2 AIF82899.1 - 4.5e-13 49.7 0.1 5.6e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AIF82899.1 - 3e-10 40.1 0.2 4.3e-07 29.7 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIF82899.1 - 2e-08 34.9 0.2 9.5e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 AIF82899.1 - 2.8e-05 23.4 0.0 6.8e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 AIF82899.1 - 4.2e-05 23.8 0.1 0.00076 19.7 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AIF82899.1 - 0.024 14.3 0.0 0.083 12.6 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like Cyclotide PF03784.8 AIF82899.1 - 0.056 13.3 0.8 0.1 12.4 0.6 1.3 1 0 0 1 1 1 0 Cyclotide family MerT PF02411.10 AIF82900.1 - 0.015 15.1 3.1 0.015 15.1 2.1 2.5 2 1 0 2 2 2 0 MerT mercuric transport protein DNase-RNase PF02577.9 AIF82901.1 - 9.5e-10 37.8 0.0 1.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease DUF1297 PF06973.7 AIF82902.1 - 8.7e-75 250.1 0.2 1.2e-74 249.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 AIF82902.1 - 2.2e-46 156.6 0.1 8e-46 154.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1246) ATP-grasp_4 PF13535.1 AIF82902.1 - 0.00036 20.3 0.0 0.00084 19.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain MttA_Hcf106 PF02416.11 AIF82903.1 - 1.5e-10 40.0 0.5 1e-09 37.3 0.2 2.0 2 0 0 2 2 2 1 mttA/Hcf106 family DUF4288 PF14119.1 AIF82903.1 - 0.0089 16.1 0.4 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4288) Selenoprotein_S PF06936.6 AIF82903.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Slx4 PF09494.5 AIF82903.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Slx4 endonuclease TatC PF00902.13 AIF82904.1 - 1.4e-55 188.0 19.8 1.7e-55 187.7 13.7 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) HEAT_2 PF13646.1 AIF82906.1 - 2.4e-24 85.4 0.4 2.9e-15 56.2 0.1 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 AIF82906.1 - 4.1e-12 45.0 0.4 0.1 12.7 0.0 4.2 4 0 0 4 4 4 4 HEAT repeat HEAT_EZ PF13513.1 AIF82906.1 - 5.9e-12 45.6 0.1 0.035 14.6 0.0 4.1 4 0 0 4 4 4 3 HEAT-like repeat HEAT_PBS PF03130.11 AIF82906.1 - 4e-11 42.2 0.2 0.073 13.5 0.0 4.2 4 0 0 4 4 4 3 PBS lyase HEAT-like repeat Arm PF00514.18 AIF82906.1 - 2.5e-05 23.9 0.4 0.97 9.3 0.0 4.0 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 AIF82906.1 - 0.012 14.7 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Cnd1 PF12717.2 AIF82906.1 - 0.034 13.9 0.5 11 5.8 0.0 3.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 AIF82906.1 - 0.044 12.0 0.3 0.44 8.7 0.2 2.1 1 1 1 2 2 2 0 Adaptin N terminal region DUF4042 PF13251.1 AIF82906.1 - 0.077 12.4 0.1 16 4.8 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) DUF3385 PF11865.3 AIF82906.1 - 0.12 12.2 0.0 9.9 6.0 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Glyoxalase_2 PF12681.2 AIF82908.1 - 5.3e-11 43.0 0.0 6.5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF82908.1 - 0.012 15.6 0.0 0.16 11.9 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_4 PF02390.12 AIF82909.1 - 1.8e-06 27.1 0.0 4.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase HD PF01966.17 AIF82909.1 - 1.1e-05 25.3 0.0 3.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.14 AIF82909.1 - 0.098 12.3 0.1 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Nitroreductase PF00881.19 AIF82910.1 - 2.7e-26 92.3 0.0 4.2e-26 91.7 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family N6_N4_Mtase PF01555.13 AIF82911.1 - 2.5e-47 161.3 0.0 1.8e-46 158.4 0.0 1.9 1 1 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 AIF82911.1 - 1e-16 61.0 0.0 2.6e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.13 AIF82911.1 - 7.6e-07 28.8 0.0 0.00027 20.5 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 MTS PF05175.9 AIF82911.1 - 0.00023 20.6 0.0 0.0049 16.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIF82911.1 - 0.0028 18.2 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF82911.1 - 0.017 14.7 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 AIF82911.1 - 0.096 12.0 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 AIF82911.1 - 0.098 12.2 0.0 0.72 9.3 0.0 2.3 3 0 0 3 3 3 0 RNA cap guanine-N2 methyltransferase Zn_ribbon_recom PF13408.1 AIF82912.1 - 0.053 13.7 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C3HC PF07967.8 AIF82912.1 - 0.086 12.5 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 C3HC zinc finger-like zf-Di19 PF05605.7 AIF82912.1 - 0.099 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.1 AIF82912.1 - 0.15 11.8 0.1 0.2 11.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) Tom5 PF10642.4 AIF82912.1 - 0.21 11.2 1.6 0.39 10.3 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF482 PF04339.7 AIF82915.1 - 0.0014 17.5 1.5 0.0014 17.5 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF482 DUF4196 PF13846.1 AIF82915.1 - 0.34 11.2 3.1 0.38 11.0 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) ARGLU PF15346.1 AIF82915.1 - 1 9.1 10.9 4.9 6.9 3.2 2.0 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 PHP_C PF13263.1 AIF82918.1 - 2e-08 33.5 0.0 3.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PHP-associated PHP PF02811.14 AIF82918.1 - 9.4e-05 22.2 0.2 0.00014 21.6 0.1 1.3 1 0 0 1 1 1 1 PHP domain TFIIA_gamma_N PF02268.11 AIF82918.1 - 0.0052 16.3 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TRAM PF01938.15 AIF82919.1 - 4.4e-14 51.9 3.0 5.1e-14 51.8 2.1 1.1 1 0 0 1 1 1 1 TRAM domain S1 PF00575.18 AIF82919.1 - 0.1 12.7 3.4 3.9 7.6 0.3 2.3 1 1 0 2 2 2 0 S1 RNA binding domain Isochorismatase PF00857.15 AIF82920.1 - 2.5e-41 141.5 0.0 3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family zf-AN1 PF01428.11 AIF82922.1 - 2.9e-11 43.0 6.0 4.4e-11 42.4 4.2 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Peptidase_M50 PF02163.17 AIF82922.1 - 2.2e-09 36.5 13.7 3.6e-08 32.6 9.5 2.2 1 1 0 1 1 1 1 Peptidase family M50 DUF2085 PF09858.4 AIF82922.1 - 0.37 10.9 3.5 0.43 10.6 0.2 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) zf-MIZ PF02891.15 AIF82922.1 - 1 8.9 3.7 1.7 8.2 2.6 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF2024 PF09630.5 AIF82923.1 - 3.8e-09 36.1 0.3 1.8e-08 33.9 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2024) Guanylate_cyc PF00211.15 AIF82926.1 - 9.7e-15 54.4 0.0 1.3e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.19 AIF82927.1 - 1.1e-21 76.9 0.3 1.2e-21 76.8 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AIF82928.1 - 6.7e-28 96.6 0.0 1.5e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 AIF82928.1 - 9.7e-20 70.8 0.0 2.9e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain HAMP PF00672.20 AIF82928.1 - 8.8e-16 57.8 0.1 8.8e-16 57.8 0.0 2.7 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.20 AIF82928.1 - 1.4e-15 56.9 1.4 4.1e-15 55.5 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 AIF82928.1 - 4.3e-12 45.8 0.0 1.4e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 AIF82928.1 - 5.6e-11 42.3 0.1 1.3e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 AIF82928.1 - 2.3e-09 37.2 0.0 5.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 AIF82928.1 - 0.0098 15.7 0.0 0.05 13.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain Cache_3 PF14827.1 AIF82928.1 - 0.011 15.6 0.9 0.032 14.1 0.1 2.2 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase HATPase_c_2 PF13581.1 AIF82928.1 - 0.042 13.6 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Bacillus_HBL PF05791.6 AIF82928.1 - 0.32 10.3 5.0 5.6 6.2 0.3 3.3 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AA_permease_2 PF13520.1 AIF82929.1 - 4e-39 134.3 48.5 5.2e-39 133.9 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AIF82929.1 - 1.5e-35 122.5 42.6 2e-35 122.0 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease Usp PF00582.21 AIF82929.1 - 1.7e-07 31.4 0.2 0.0068 16.6 0.0 3.1 2 1 0 2 2 2 2 Universal stress protein family AA_permease_C PF13906.1 AIF82929.1 - 5.9e-06 26.0 6.5 5.9e-06 26.0 4.5 3.1 2 0 0 2 2 2 1 C-terminus of AA_permease MobB PF03205.9 AIF82930.1 - 1.2e-09 38.0 0.1 1.3e-08 34.6 0.1 2.3 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AIF82930.1 - 0.027 13.9 0.0 0.095 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 AIF82930.1 - 0.046 14.5 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain QueC PF06508.8 AIF82931.1 - 1.7e-45 154.8 0.0 1.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 AIF82931.1 - 4.1e-07 29.6 0.0 5.2e-06 26.0 0.0 2.4 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.15 AIF82931.1 - 0.00037 20.0 0.0 0.00071 19.1 0.0 1.4 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 AIF82931.1 - 0.0021 16.9 0.0 0.027 13.3 0.0 2.0 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 AIF82931.1 - 0.0024 17.4 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_4 PF01902.12 AIF82931.1 - 0.0045 16.3 0.0 0.0085 15.4 0.0 1.4 1 1 0 1 1 1 1 ATP-binding region PTPS PF01242.14 AIF82932.1 - 9.6e-19 67.2 0.0 2.3e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase Asn_synthase PF00733.16 AIF82934.1 - 6.6e-37 127.3 0.1 3e-36 125.2 0.1 1.8 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AIF82934.1 - 2.3e-08 33.2 0.0 3.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 AIF82934.1 - 2.2e-06 27.1 0.0 3.2e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AIF82934.1 - 0.00035 19.2 0.1 0.00082 18.0 0.1 1.6 1 1 0 1 1 1 1 tRNA methyl transferase ATP_bind_3 PF01171.15 AIF82934.1 - 0.0028 17.1 0.1 0.0063 16.0 0.0 1.8 2 0 0 2 2 2 1 PP-loop family HTH_45 PF14947.1 AIF82935.1 - 0.0025 17.6 1.1 0.0027 17.4 0.2 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix Sulfolobus_pRN PF05584.6 AIF82935.1 - 0.003 17.4 0.1 0.0056 16.6 0.1 1.4 1 0 0 1 1 1 1 Sulfolobus plasmid regulatory protein Rad17 PF03215.10 AIF82935.1 - 0.052 12.2 0.2 0.059 12.0 0.1 1.0 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TrmB PF01978.14 AIF82935.1 - 0.068 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rio2_N PF09202.6 AIF82935.1 - 0.092 12.8 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Rio2, N-terminal HTH_27 PF13463.1 AIF82935.1 - 0.12 12.7 0.5 2.1 8.7 0.4 2.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain YhzD PF14120.1 AIF82935.1 - 0.14 12.1 0.2 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 YhzD-like protein UbiA PF01040.13 AIF82936.1 - 4.1e-31 108.1 15.2 4.5e-31 107.9 10.2 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Lig_chan PF00060.21 AIF82936.1 - 5.5 6.6 5.7 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel HTH_45 PF14947.1 AIF82937.1 - 8.3e-05 22.3 0.3 0.0002 21.1 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_20 PF12840.2 AIF82937.1 - 0.015 15.0 0.0 0.066 13.0 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_24 PF13412.1 AIF82937.1 - 0.024 14.0 0.3 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Abhydrolase_6 PF12697.2 AIF82938.1 - 1.3e-29 103.7 0.0 1.6e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIF82938.1 - 1.1e-20 73.8 0.0 1.6e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AIF82938.1 - 7.3e-12 44.9 0.0 2.3e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 AIF82938.1 - 7e-11 42.1 0.1 2.1e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AIF82938.1 - 2.4e-06 26.9 0.0 0.00016 21.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2305 PF10230.4 AIF82938.1 - 3.8e-05 23.2 0.2 9.3e-05 21.9 0.2 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 AIF82938.1 - 0.00017 21.1 0.0 0.36 10.2 0.0 3.0 2 1 0 2 2 2 2 Serine hydrolase (FSH1) DUF1057 PF06342.7 AIF82938.1 - 0.0002 20.2 0.0 0.00035 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.13 AIF82938.1 - 0.001 18.4 0.0 0.027 13.7 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF1749 PF08538.5 AIF82938.1 - 0.0019 17.1 0.0 0.0038 16.1 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.8 AIF82938.1 - 0.0088 15.6 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 AIF82938.1 - 0.0097 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Annexin PF00191.15 AIF82938.1 - 0.01 15.7 0.0 0.054 13.3 0.0 2.2 1 1 1 2 2 2 0 Annexin Peptidase_S15 PF02129.13 AIF82938.1 - 0.024 14.0 0.0 0.19 11.1 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3530 PF12048.3 AIF82938.1 - 0.037 13.0 0.0 2.2 7.2 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) Ser_hydrolase PF06821.8 AIF82938.1 - 0.046 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.10 AIF82938.1 - 0.059 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Methyltransf_31 PF13847.1 AIF82939.1 - 3.5e-20 72.1 0.0 4.7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF82939.1 - 1.7e-16 60.4 0.1 2.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF82939.1 - 3.5e-14 52.9 0.1 7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF82939.1 - 1.7e-13 50.6 0.0 2.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF82939.1 - 3.4e-13 50.1 0.0 5.7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF82939.1 - 3.1e-10 40.4 0.0 5.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF82939.1 - 1.9e-09 36.9 0.0 2.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 AIF82939.1 - 3.6e-06 27.0 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 AIF82939.1 - 1.2e-05 25.2 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AIF82939.1 - 1.6e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 AIF82939.1 - 2.6e-05 23.0 0.0 4.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 AIF82939.1 - 0.00011 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 AIF82939.1 - 0.00024 21.9 0.0 0.00039 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF82939.1 - 0.00044 19.6 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.5 AIF82939.1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GidB PF02527.10 AIF82939.1 - 0.0072 15.4 0.0 0.015 14.4 0.0 1.4 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G RrnaAD PF00398.15 AIF82939.1 - 0.0096 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 AIF82939.1 - 0.057 12.6 0.1 0.53 9.5 0.1 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain ADK_lid PF05191.9 AIF82940.1 - 0.26 10.9 2.6 3.8 7.2 0.2 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid PHO4 PF01384.15 AIF82941.1 - 3e-95 318.5 35.6 3.7e-95 318.3 24.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF3318 PF11780.3 AIF82941.1 - 0.59 9.6 4.5 0.78 9.3 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) PhoU_div PF01865.11 AIF82942.1 - 1.2e-25 89.9 6.6 1.4e-25 89.7 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PMC2NT PF08066.7 AIF82942.1 - 0.027 14.7 0.7 0.14 12.4 0.1 2.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain zf-C2H2_4 PF13894.1 AIF82943.1 - 0.001 19.2 1.9 0.011 15.9 0.5 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF82943.1 - 0.0029 17.8 1.5 0.0074 16.5 0.4 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF1644 PF07800.7 AIF82943.1 - 0.028 14.2 0.2 2.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zf-C2H2_jaz PF12171.3 AIF82943.1 - 0.03 14.4 1.3 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.2 AIF82943.1 - 0.051 13.5 1.2 0.058 13.3 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding zf-DBF PF07535.7 AIF82943.1 - 0.17 11.5 0.9 6.7 6.4 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-H2C2_5 PF13909.1 AIF82943.1 - 0.49 10.7 4.0 1.5 9.2 0.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Defensin_beta_2 PF13841.1 AIF82944.1 - 0.11 12.8 3.8 0.23 11.8 0.1 2.4 2 1 0 2 2 2 0 Beta defensin DUF796 PF05638.7 AIF82945.1 - 3.7e-41 140.2 0.1 5e-41 139.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF796) SSURE PF11966.3 AIF82945.1 - 0.038 13.5 0.1 0.1 12.1 0.1 1.7 1 1 1 2 2 2 0 Fibronectin-binding repeat DUF72 PF01904.13 AIF82947.1 - 6e-61 206.1 0.3 7.6e-61 205.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 CHZ PF09649.5 AIF82950.1 - 0.11 11.7 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ Annexin PF00191.15 AIF82950.1 - 0.16 11.9 0.2 0.41 10.5 0.1 1.7 1 1 0 1 1 1 0 Annexin HxlR PF01638.12 AIF82952.1 - 0.0087 15.6 0.0 0.014 14.9 0.0 1.3 1 1 0 1 1 1 1 HxlR-like helix-turn-helix DUF1811 PF08838.5 AIF82953.1 - 0.32 10.9 3.3 0.41 10.6 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1811) TSC22 PF01166.13 AIF82953.1 - 8.5 6.4 10.1 1.1 9.2 1.1 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family Thioredoxin PF00085.15 AIF82954.1 - 6.5e-26 90.0 0.0 7.8e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AIF82954.1 - 7e-07 29.4 0.0 1.7e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AIF82954.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIF82954.1 - 1.3e-05 25.1 0.0 0.0044 17.0 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 AIF82954.1 - 2.4e-05 24.2 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 AIF82954.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TrbC_Ftype PF09673.5 AIF82954.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_4 PF13462.1 AIF82954.1 - 0.11 12.5 0.0 9.3 6.2 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin HyaE PF07449.6 AIF82954.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TrmB PF01978.14 AIF82955.1 - 1.4e-08 34.3 0.2 8.7e-07 28.5 0.0 2.0 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AIF82955.1 - 2.8e-06 26.8 0.4 8.1e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 MarR family MarR PF01047.17 AIF82955.1 - 4.4e-06 26.3 0.2 1.6e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.5 AIF82955.1 - 7e-06 25.5 0.4 1.3e-05 24.6 0.3 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_27 PF13463.1 AIF82955.1 - 0.0019 18.4 0.0 0.0028 17.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_11 PF08279.7 AIF82955.1 - 0.0034 16.9 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.1 AIF82955.1 - 0.0063 15.8 0.9 0.024 14.0 0.0 2.2 2 1 1 3 3 3 1 Winged helix-turn-helix DNA-binding DUF883 PF05957.8 AIF82955.1 - 0.021 15.2 0.9 0.034 14.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HrcA_DNA-bdg PF03444.10 AIF82955.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Nbl1_Borealin_N PF10444.4 AIF82955.1 - 0.067 12.5 0.3 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal HTH_29 PF13551.1 AIF82955.1 - 0.077 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn helix DUF1469 PF07332.6 AIF82956.1 - 0.0018 17.9 3.5 0.0021 17.7 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) DUF4203 PF13886.1 AIF82956.1 - 0.0079 15.6 0.3 0.0079 15.6 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4501 PF14946.1 AIF82956.1 - 0.037 13.5 0.2 0.042 13.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Usp PF00582.21 AIF82957.1 - 4.7e-29 101.3 0.0 5.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family HTH_42 PF06224.7 AIF82957.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain Flavodoxin_1 PF00258.20 AIF82958.1 - 5e-07 29.8 0.0 8.5e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.2 AIF82958.1 - 1.8e-06 27.4 0.0 2.7e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.2 AIF82958.1 - 2.8e-06 27.4 0.0 8.7e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin domain DUF4598 PF15370.1 AIF82958.1 - 0.028 14.6 0.1 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) Flavodoxin_4 PF12682.2 AIF82958.1 - 0.12 11.6 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Flavodoxin DUF3040 PF11239.3 AIF82959.1 - 3 7.9 10.1 0.62 10.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RDD PF06271.7 AIF82960.1 - 2.6e-14 53.2 7.6 1.6e-13 50.7 5.3 1.9 1 1 0 1 1 1 1 RDD family PqqD PF05402.7 AIF82961.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) DUF3143 PF11341.3 AIF82961.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) FctA PF12892.2 AIF82962.1 - 0.032 15.0 0.1 0.049 14.4 0.1 1.2 1 0 0 1 1 1 0 T surface-antigen of pili DUF998 PF06197.8 AIF82963.1 - 0.71 9.1 14.6 0.86 8.8 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF202 PF02656.10 AIF82963.1 - 1 9.5 5.4 5.2 7.3 3.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Usp PF00582.21 AIF82964.1 - 1.2e-27 96.8 1.6 1.7e-26 93.0 1.1 2.4 1 1 0 1 1 1 1 Universal stress protein family ADH_zinc_N PF00107.21 AIF82965.1 - 2e-33 114.6 0.1 3.3e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIF82965.1 - 2.6e-26 91.4 0.2 4.7e-26 90.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIF82965.1 - 6.2e-16 59.4 0.0 1.4e-15 58.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 AIF82965.1 - 0.0068 16.0 0.2 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 AIF82965.1 - 0.023 14.7 0.3 0.044 13.7 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_18 PF12847.2 AIF82965.1 - 0.083 13.4 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CBS PF00571.23 AIF82966.1 - 9.4e-13 47.7 0.1 0.00012 21.7 0.0 3.5 3 0 0 3 3 3 3 CBS domain HTH_23 PF13384.1 AIF82967.1 - 0.00019 20.9 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_ECF PF07638.6 AIF82967.1 - 0.00052 19.7 0.1 0.00052 19.7 0.0 1.0 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4_2 PF08281.7 AIF82967.1 - 0.0012 18.2 0.1 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_7 PF02796.10 AIF82967.1 - 0.0012 18.6 0.1 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 AIF82967.1 - 0.0027 17.2 0.2 0.0034 16.9 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.14 AIF82967.1 - 0.0067 15.7 0.0 0.0073 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 AIF82967.1 - 0.011 15.6 0.1 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 AIF82967.1 - 0.016 14.4 0.2 0.018 14.3 0.2 1.1 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 AIF82967.1 - 0.031 13.4 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GcrA PF07750.6 AIF82967.1 - 0.1 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator Rrf2 PF02082.15 AIF82967.1 - 0.1 12.6 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 Transcriptional regulator AA_permease_2 PF13520.1 AIF82968.1 - 8.1e-56 189.3 52.6 9.2e-56 189.1 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AIF82968.1 - 9.3e-40 136.3 50.0 1.2e-39 135.9 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease Usp PF00582.21 AIF82969.1 - 3.4e-35 121.2 0.3 3.7e-35 121.1 0.2 1.0 1 0 0 1 1 1 1 Universal stress protein family RNA_pol_L PF01193.19 AIF82969.1 - 0.22 10.6 0.6 5 6.3 0.0 2.5 2 1 1 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain TPR_16 PF13432.1 AIF82969.1 - 0.86 10.3 3.4 0.4 11.4 0.9 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CBS PF00571.23 AIF82970.1 - 1.9e-32 110.7 3.2 7.9e-17 60.7 0.1 2.1 2 0 0 2 2 2 2 CBS domain SAF_2 PF13144.1 AIF82970.1 - 0.037 13.5 0.7 0.053 13.0 0.4 1.4 1 1 0 1 1 1 0 SAF-like Wzz PF02706.10 AIF82970.1 - 0.079 12.7 0.2 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 Chain length determinant protein CBS PF00571.23 AIF82971.1 - 3.2e-23 81.2 2.5 6.4e-12 45.0 0.2 2.2 2 0 0 2 2 2 2 CBS domain zf-C2H2_4 PF13894.1 AIF82971.1 - 4e-05 23.6 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF82971.1 - 0.0009 19.4 0.1 0.0014 18.8 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 AIF82971.1 - 0.0028 17.7 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 AIF82971.1 - 0.032 14.2 0.1 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 zinc-finger Coiled PF05710.7 AIF82971.1 - 0.71 10.3 4.2 0.17 12.3 0.4 1.8 2 0 0 2 2 2 0 Coiled coil Usp PF00582.21 AIF82972.1 - 1.2e-27 96.8 0.5 1.4e-27 96.6 0.4 1.1 1 0 0 1 1 1 1 Universal stress protein family Peripla_BP_4 PF13407.1 AIF82972.1 - 0.018 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF4415 PF14384.1 AIF82973.1 - 0.034 14.2 0.1 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4415) HicB PF05534.7 AIF82973.1 - 0.039 13.5 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 HicB family Terminase_2 PF03592.11 AIF82973.1 - 0.11 12.7 0.2 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Terminase small subunit SnoaL_2 PF12680.2 AIF82974.1 - 0.0013 19.0 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 AIF82974.1 - 0.044 13.6 0.0 0.082 12.8 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.15 AIF82974.1 - 0.048 14.0 0.0 0.06 13.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 AIF82974.1 - 0.074 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 AIF82974.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association CBS PF00571.23 AIF82976.1 - 2e-25 88.2 3.4 5.2e-13 48.5 0.0 2.6 2 1 0 2 2 2 2 CBS domain DUF3703 PF12487.3 AIF82976.1 - 0.053 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) P-II PF00543.17 AIF82977.1 - 0.0021 18.5 0.0 0.0022 18.4 0.0 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Cu-oxidase_3 PF07732.10 AIF82978.1 - 7.7e-25 86.9 4.7 3.1e-24 84.9 0.8 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AIF82978.1 - 9.5e-19 67.2 8.0 1.6e-07 30.8 0.0 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 AIF82978.1 - 4.8e-10 39.2 0.1 0.00014 21.6 0.0 3.9 4 0 0 4 4 4 2 Cupredoxin-like domain Copper-bind PF00127.15 AIF82978.1 - 9.4e-08 32.2 7.4 0.00087 19.4 0.9 3.8 3 2 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family COX2 PF00116.15 AIF82978.1 - 0.02 14.7 1.0 0.048 13.4 0.2 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, periplasmic domain COX1 PF00115.15 AIF82979.1 - 0.00025 19.8 11.3 0.00025 19.8 7.8 2.0 1 1 1 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I DUF4271 PF14093.1 AIF82979.1 - 0.36 10.4 4.9 0.092 12.4 1.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) DUF4231 PF14015.1 AIF82979.1 - 1.1 9.2 6.1 0.28 11.1 0.3 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF4231) ABC2_membrane_4 PF12730.2 AIF82979.1 - 1.6 7.7 13.7 0.16 11.1 1.8 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein VIT1 PF01988.14 AIF82981.1 - 4.8e-67 225.5 5.2 5.4e-67 225.3 3.6 1.0 1 0 0 1 1 1 1 VIT family IncA PF04156.9 AIF82981.1 - 0.023 14.2 0.0 0.023 14.2 0.0 2.8 3 1 0 3 3 3 0 IncA protein Usp PF00582.21 AIF82983.1 - 1.8e-30 105.9 0.0 2.1e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Cupredoxin_1 PF13473.1 AIF82984.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 1 1 2 2 2 1 Cupredoxin-like domain Kin17_mid PF10357.4 AIF82985.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein DUF234 PF03008.9 AIF82985.1 - 0.0055 16.7 0.2 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Archaea bacterial proteins of unknown function DUF4290 PF14123.1 AIF82985.1 - 0.081 12.1 0.9 0.35 10.0 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4290) DUF3681 PF12442.3 AIF82987.1 - 0.0012 18.9 1.5 0.0015 18.6 1.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3681) DUF3624 PF12292.3 AIF82987.1 - 0.031 14.6 2.9 0.038 14.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Cytochrom_B_N PF00033.14 AIF82987.1 - 0.07 12.4 3.1 0.087 12.1 2.2 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB MARVEL PF01284.18 AIF82987.1 - 0.089 12.6 3.4 0.093 12.5 2.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF2142 PF09913.4 AIF82987.1 - 0.14 10.7 5.4 0.17 10.5 3.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF2207 PF09972.4 AIF82987.1 - 0.58 8.6 5.0 0.62 8.5 3.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) COX15-CtaA PF02628.10 AIF82987.1 - 0.92 8.3 5.5 1.1 8.0 3.8 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Orai-1 PF07856.7 AIF82987.1 - 1.4 8.4 6.9 1.6 8.2 4.8 1.0 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF2427 PF10348.4 AIF82987.1 - 2 8.0 5.6 2.3 7.8 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF1469 PF07332.6 AIF82987.1 - 2.2 8.0 5.2 2.6 7.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) PIG-H PF10181.4 AIF82989.1 - 0.029 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component ResIII PF04851.10 AIF82990.1 - 4.1e-13 49.5 0.2 1.4e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AIF82990.1 - 4.2e-11 42.5 0.0 1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIF82990.1 - 4.9e-09 35.9 0.0 3.3e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.1 AIF82990.1 - 0.014 15.0 0.1 0.06 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 AIF82990.1 - 0.019 13.9 0.7 0.059 12.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AIF82990.1 - 0.021 14.5 0.0 8.9 6.1 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain CdhD PF03599.11 AIF82990.1 - 0.049 12.1 0.3 0.099 11.1 0.2 1.4 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Rsm22 PF09243.5 AIF82990.1 - 0.084 11.8 0.1 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 IstB_IS21 PF01695.12 AIF82990.1 - 0.095 12.1 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein TP_methylase PF00590.15 AIF82992.1 - 5.8e-34 117.6 0.0 6.8e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF3237 PF11578.3 AIF82993.1 - 0.089 12.0 0.2 0.11 11.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3237) DUF4278 PF14105.1 AIF82993.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) PepSY PF03413.14 AIF82994.1 - 0.00062 20.3 0.2 0.0013 19.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DUF2090 PF09863.4 AIF82994.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) DUF4244 PF14029.1 AIF82995.1 - 0.034 13.2 0.1 0.039 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) DUF1967 PF09269.6 AIF82995.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DUF2795 PF11387.3 AIF82996.1 - 7.2e-06 25.7 0.1 1.5e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) zf-C2H2_4 PF13894.1 AIF82996.1 - 0.00032 20.8 0.0 0.00054 20.1 0.0 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF82996.1 - 0.0011 19.1 0.1 0.0018 18.5 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AIF82996.1 - 0.016 15.1 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.7 AIF82996.1 - 0.027 14.6 0.1 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 AIF82996.1 - 0.074 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF3088 PF11287.3 AIF82996.1 - 0.17 11.3 0.7 1.3 8.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3088) zf-H2C2_2 PF13465.1 AIF82996.1 - 0.21 11.9 2.2 9.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DUF4367 PF14285.1 AIF82997.1 - 0.00086 18.6 2.8 0.35 10.1 0.0 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4367) DUF2611 PF11022.3 AIF82997.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) PepSY PF03413.14 AIF83001.1 - 1.2e-06 29.0 0.6 0.0072 16.9 0.0 2.4 2 1 0 2 2 2 2 Peptidase propeptide and YPEB domain Transposase_31 PF04754.7 AIF83001.1 - 0.0054 16.1 0.0 0.0075 15.6 0.0 1.1 1 0 0 1 1 1 1 Putative transposase, YhgA-like GRIM-19 PF06212.7 AIF83002.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 GRIM-19 protein DUF106 PF01956.11 AIF83002.1 - 0.038 13.5 0.2 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF106 YbjM PF11045.3 AIF83002.1 - 0.046 13.4 1.1 0.19 11.4 0.7 1.8 1 1 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae NPR1_like_C PF12313.3 AIF83002.1 - 0.11 11.9 0.8 0.14 11.5 0.6 1.1 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal HTH_45 PF14947.1 AIF83003.1 - 7.6e-08 32.0 0.7 9.5e-08 31.7 0.5 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 AIF83003.1 - 1.2e-05 24.8 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF83003.1 - 0.00085 18.9 0.1 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AIF83003.1 - 0.0025 17.1 0.4 0.0042 16.4 0.1 1.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Toxin_64 PF15542.1 AIF83003.1 - 0.0045 17.5 0.2 0.0055 17.2 0.1 1.2 1 0 0 1 1 1 1 Putative toxin 64 DUF2250 PF10007.4 AIF83003.1 - 0.012 15.5 0.3 0.23 11.3 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HxlR PF01638.12 AIF83003.1 - 0.038 13.6 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix 7TM-7TMR_HD PF07698.6 AIF83004.1 - 0.034 13.6 8.4 0.043 13.2 5.8 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF4131 PF13567.1 AIF83004.1 - 9.2 5.6 8.3 0.6 9.4 2.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ABC_tran PF00005.22 AIF83005.1 - 7.1e-36 123.5 0.0 1e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF83005.1 - 2.3e-14 54.0 0.3 6.9e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 AIF83005.1 - 1.3e-07 31.1 0.8 0.0031 16.7 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AIF83005.1 - 1.3e-07 31.0 0.1 1.8e-05 23.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AIF83005.1 - 9.2e-06 26.4 0.0 1.6e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AIF83005.1 - 1.8e-05 24.1 0.1 3.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 AIF83005.1 - 7.6e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AIF83005.1 - 8.5e-05 22.6 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIF83005.1 - 0.00014 21.9 0.2 0.00077 19.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AIF83005.1 - 0.00037 20.0 0.8 0.0021 17.5 0.4 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 AIF83005.1 - 0.00048 19.5 0.2 0.0094 15.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AIF83005.1 - 0.00073 19.8 0.7 0.0035 17.6 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIF83005.1 - 0.0013 18.5 0.5 0.011 15.6 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AIF83005.1 - 0.0024 18.2 0.2 0.0059 16.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 AIF83005.1 - 0.0046 16.4 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 AIF83005.1 - 0.0056 16.6 1.4 0.012 15.5 0.9 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 AIF83005.1 - 0.013 15.1 0.1 0.038 13.6 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 AIF83005.1 - 0.015 14.9 0.1 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AIF83005.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AIF83005.1 - 0.021 14.3 0.1 0.05 13.0 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 AIF83005.1 - 0.036 13.9 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 AIF83005.1 - 0.047 13.1 0.1 0.078 12.4 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 AIF83005.1 - 0.047 13.0 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 AIF83005.1 - 0.058 11.9 0.0 1.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.15 AIF83005.1 - 0.067 11.8 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.7 AIF83005.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_24 PF13479.1 AIF83005.1 - 0.12 11.9 0.1 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AIF83005.1 - 0.12 12.1 0.3 0.32 10.8 0.2 1.7 1 0 0 1 1 1 0 Dynamin family NPCBM_assoc PF10633.4 AIF83006.1 - 2e-06 27.7 7.7 0.012 15.6 0.3 4.7 4 0 0 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase TRAP_alpha PF03896.11 AIF83006.1 - 0.012 14.6 0.1 0.18 10.7 0.0 2.4 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TRAP_beta PF05753.9 AIF83006.1 - 1.1 8.4 4.3 3.8 6.6 0.0 3.4 4 0 0 4 4 4 0 Translocon-associated protein beta (TRAPB) MacB_PCD PF12704.2 AIF83007.1 - 7.6e-27 94.3 3.2 7.6e-27 94.3 2.2 2.6 3 0 0 3 3 3 2 MacB-like periplasmic core domain FtsX PF02687.16 AIF83007.1 - 2e-23 82.4 6.5 2e-23 82.4 4.5 1.9 2 0 0 2 2 2 1 FtsX-like permease family CedA PF10729.4 AIF83008.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Cell division activator CedA AA_kinase PF00696.23 AIF83009.1 - 3.4e-53 180.6 0.9 3.4e-53 180.6 0.6 2.0 2 1 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 AIF83009.1 - 9.8e-23 79.4 2.4 3.1e-11 42.6 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 AIF83009.1 - 8.1e-22 76.2 0.4 1.2e-10 40.6 0.1 2.9 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.1 AIF83009.1 - 0.026 14.2 2.8 0.14 11.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain LytR_C PF13399.1 AIF83009.1 - 0.03 14.6 0.2 0.9 9.9 0.0 2.5 1 1 1 2 2 2 0 LytR cell envelope-related transcriptional attenuator PCNA_N PF00705.13 AIF83010.1 - 6.5e-18 64.4 0.0 7.9e-17 60.9 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AIF83010.1 - 1.8e-16 60.2 0.1 1.7e-14 53.8 0.0 2.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 AIF83010.1 - 6.3e-09 34.9 0.1 0.00018 20.4 0.0 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 AIF83010.1 - 7.5e-05 21.9 0.0 0.0001 21.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Cation_efflux PF01545.16 AIF83011.1 - 4.8e-47 160.3 5.6 5.9e-47 160.1 3.9 1.0 1 0 0 1 1 1 1 Cation efflux family GARS_A PF01071.14 AIF83012.1 - 1.5e-15 57.2 0.0 3.6e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C PF02843.11 AIF83012.1 - 5.3e-09 36.1 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 AIF83012.1 - 9.3e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain AsnC_trans_reg PF01037.16 AIF83013.1 - 5.3e-15 54.8 0.3 5.9e-15 54.7 0.2 1.1 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AIF83013.1 - 0.0052 16.4 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 GYD domain ACT_4 PF13291.1 AIF83013.1 - 0.043 14.1 0.4 5.2 7.4 0.1 2.4 1 1 1 2 2 2 0 ACT domain Herpes_U44 PF04533.8 AIF83013.1 - 0.14 11.3 0.2 0.19 10.9 0.1 1.3 1 1 0 1 1 1 0 Herpes virus U44 protein PhoD PF09423.5 AIF83014.1 - 5.8e-08 31.7 0.5 0.00048 18.8 0.6 2.8 2 1 0 2 2 2 2 PhoD-like phosphatase Transport_MerF PF11431.3 AIF83015.1 - 7.5e-05 22.3 0.8 0.00027 20.5 0.6 1.9 1 0 0 1 1 1 1 Membrane transport protein MerF Glycos_transf_4 PF00953.16 AIF83015.1 - 0.11 12.3 1.5 0.13 12.1 1.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 Potass_KdpF PF09604.5 AIF83016.1 - 0.19 11.6 7.2 2.9 7.8 5.0 2.4 1 1 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) KdpC PF02669.10 AIF83017.1 - 7.2e-28 97.5 0.1 2.9e-19 69.4 0.0 2.0 1 1 1 2 2 2 2 K+-transporting ATPase, c chain E1-E2_ATPase PF00122.15 AIF83018.1 - 1.6e-36 125.4 0.8 3.1e-36 124.5 0.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AIF83018.1 - 6.5e-31 108.4 1.8 1.1e-30 107.7 1.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIF83018.1 - 9.5e-13 48.7 0.0 2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AIF83018.1 - 0.00098 18.7 3.6 0.00098 18.7 0.7 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SpoIIIAC PF06686.6 AIF83018.1 - 0.026 14.2 0.5 0.026 14.2 0.3 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Aminotran_4 PF01063.14 AIF83018.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class IV KdpA PF03814.10 AIF83019.1 - 2.7e-79 266.6 28.5 4.1e-78 262.7 19.8 2.0 1 1 0 1 1 1 1 Potassium-transporting ATPase A subunit KdpA PF03814.10 AIF83020.1 - 7.7e-62 209.0 5.4 9e-62 208.8 3.8 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit HAMP PF00672.20 AIF83020.1 - 0.34 11.1 0.0 0.34 11.1 0.0 3.0 4 0 0 4 4 4 0 HAMP domain DUF21 PF01595.15 AIF83020.1 - 0.9 8.7 6.8 21 4.3 4.9 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF21 ABC2_membrane_4 PF12730.2 AIF83020.1 - 1.2 8.2 9.6 3.2 6.8 2.8 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein TFIIS_C PF01096.13 AIF83021.1 - 2.2e-18 65.6 7.3 2.2e-18 65.6 5.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 AIF83021.1 - 2.3e-07 30.5 8.1 5.8e-05 22.8 1.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon zf-DNA_Pol PF08996.5 AIF83021.1 - 6.5e-05 22.3 0.4 6.5e-05 22.3 0.3 1.8 2 1 0 2 2 2 1 DNA Polymerase alpha zinc finger zinc-ribbons_6 PF07191.7 AIF83021.1 - 0.00041 20.0 8.9 0.0012 18.5 0.4 2.5 2 1 0 2 2 2 1 zinc-ribbons zf-ribbon_3 PF13248.1 AIF83021.1 - 0.00051 19.1 1.2 0.00051 19.1 0.8 3.1 3 0 0 3 3 3 1 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 AIF83021.1 - 0.00067 19.2 0.9 0.00067 19.2 0.6 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Prok-RING_1 PF14446.1 AIF83021.1 - 0.00073 19.2 1.6 0.00073 19.2 1.1 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.7 AIF83021.1 - 0.0011 18.2 7.1 0.068 12.4 0.7 2.7 2 1 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 AIF83021.1 - 0.0049 16.5 17.9 0.11 12.2 1.3 4.2 3 1 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF83021.1 - 0.0081 15.7 18.4 0.089 12.3 1.1 4.2 3 1 0 3 3 3 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIF83021.1 - 0.011 15.3 11.5 0.012 15.2 0.8 2.9 1 1 2 3 3 3 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 AIF83021.1 - 0.012 15.4 11.4 0.021 14.5 0.3 3.3 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-IS66 PF13005.2 AIF83021.1 - 0.017 15.0 1.2 0.017 15.0 0.8 3.1 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Elf1 PF05129.8 AIF83021.1 - 0.018 14.7 1.6 0.018 14.7 1.1 2.8 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.3 AIF83021.1 - 0.028 13.7 0.0 0.028 13.7 0.0 3.0 2 1 1 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DNA_RNApol_7kD PF03604.8 AIF83021.1 - 0.034 13.6 9.2 0.052 13.0 1.0 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF4428 PF14471.1 AIF83021.1 - 0.04 13.6 1.4 0.24 11.1 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) Cript PF10235.4 AIF83021.1 - 0.042 14.1 0.5 0.042 14.1 0.4 2.5 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT A2L_zn_ribbon PF08792.5 AIF83021.1 - 0.11 11.9 11.8 2.5 7.6 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain Sep15_SelM PF08806.6 AIF83021.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sep15/SelM redox domain Zn-ribbon_8 PF09723.5 AIF83021.1 - 0.12 12.3 13.7 11 6.0 0.4 4.1 3 1 0 3 3 3 0 Zinc ribbon domain DUF2387 PF09526.5 AIF83021.1 - 0.26 11.2 12.5 0.23 11.4 0.5 3.0 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Ogr_Delta PF04606.7 AIF83021.1 - 0.4 10.3 10.0 19 5.0 0.1 3.4 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.1 AIF83021.1 - 0.44 10.1 13.6 0.38 10.3 3.3 3.5 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.14 AIF83021.1 - 0.49 10.1 11.1 0.36 10.5 1.1 3.0 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 AIF83021.1 - 0.75 9.8 9.8 5.3 7.1 2.3 3.2 3 1 0 3 3 3 0 zinc-finger UPF0547 PF10571.4 AIF83021.1 - 0.83 9.4 11.9 2.3 8.0 0.1 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.1 AIF83021.1 - 0.94 9.8 10.6 1.5 9.2 0.6 3.0 1 1 2 3 3 3 0 Restriction alleviation protein Lar PHF5 PF03660.9 AIF83021.1 - 0.94 9.5 5.1 1.4 8.9 0.3 2.3 1 1 0 2 2 2 0 PHF5-like protein C1_4 PF07975.7 AIF83021.1 - 0.95 9.5 11.4 1.3 9.0 0.1 3.4 2 1 0 2 2 2 0 TFIIH C1-like domain GATA PF00320.22 AIF83021.1 - 1.5 8.2 6.4 0.7 9.2 0.1 2.7 2 1 0 2 2 2 0 GATA zinc finger RPA_interact_C PF14768.1 AIF83021.1 - 1.9 8.9 8.0 7.4 7.0 2.0 2.8 1 1 1 2 2 2 0 Replication protein A interacting C-terminal IBR PF01485.16 AIF83021.1 - 2.4 8.1 13.1 2 8.3 0.9 2.9 2 1 0 2 2 2 0 IBR domain zf-RING_4 PF14570.1 AIF83021.1 - 2.6 7.7 7.6 23 4.6 1.1 3.3 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain PHD PF00628.24 AIF83021.1 - 2.9 7.6 11.5 6 6.6 0.9 3.1 2 1 0 2 2 2 0 PHD-finger UPF0515 PF15135.1 AIF83021.1 - 3.4 6.6 8.8 37 3.2 5.0 2.2 1 1 0 1 1 1 0 Uncharacterised protein UPF0515 PolC_DP2 PF03833.8 AIF83021.1 - 3.5 5.1 5.7 0.58 7.7 0.7 1.7 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 DUF3565 PF12088.3 AIF83021.1 - 4 7.2 6.9 14 5.5 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3565) Rpr2 PF04032.11 AIF83021.1 - 4 7.3 7.6 6.4 6.7 2.8 2.6 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2318 PF10080.4 AIF83021.1 - 7.4 6.3 7.4 3.8 7.3 0.6 2.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-ZPR1 PF03367.8 AIF83021.1 - 7.7 5.6 9.1 1.7 7.7 0.1 2.5 3 1 0 3 3 2 0 ZPR1 zinc-finger domain zf-AN1 PF01428.11 AIF83021.1 - 8 6.4 12.5 8.7 6.3 0.2 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger RNA_pol_L_2 PF13656.1 AIF83022.1 - 3.3e-18 64.9 0.1 3.6e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LGFP PF08310.6 AIF83023.1 - 0.018 14.6 0.1 3.8 7.2 0.0 2.8 3 0 0 3 3 3 0 LGFP repeat MarR PF01047.17 AIF83024.1 - 7.7e-14 51.1 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 AIF83024.1 - 3.4e-09 36.2 0.0 5.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AIF83024.1 - 3e-07 30.6 0.1 7.1e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.14 AIF83024.1 - 0.00014 21.4 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 AIF83024.1 - 0.0036 16.7 0.1 0.0059 16.0 0.1 1.4 1 1 0 1 1 1 1 TFIIE alpha subunit DUF2250 PF10007.4 AIF83024.1 - 0.0061 16.4 0.1 0.033 14.0 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_34 PF13601.1 AIF83024.1 - 0.0064 16.5 0.0 0.083 12.9 0.0 2.2 1 1 0 2 2 2 1 Winged helix DNA-binding domain FeoC PF09012.5 AIF83024.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator Fe_dep_repress PF01325.14 AIF83024.1 - 0.0086 16.0 0.2 0.037 13.9 0.0 2.0 2 1 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain PadR PF03551.9 AIF83024.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.15 AIF83024.1 - 0.015 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.1 AIF83024.1 - 0.04 13.7 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain B-block_TFIIIC PF04182.7 AIF83024.1 - 0.057 13.2 0.0 0.19 11.6 0.0 1.7 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC MFS_1 PF07690.11 AIF83025.1 - 2.6e-40 138.2 56.7 1.4e-30 106.2 19.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 AIF83025.1 - 0.034 12.7 0.1 0.034 12.7 0.0 3.6 2 1 2 4 4 4 0 Predicted membrane protein (DUF2207) Radical_SAM PF04055.16 AIF83026.1 - 2.1e-13 50.7 0.1 3.6e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 AIF83026.1 - 3.2e-05 24.0 0.1 8.2e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 AIF83026.1 - 0.049 13.6 0.4 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Dispanin PF04505.7 AIF83027.1 - 0.015 14.7 0.1 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Med24_N PF11277.3 AIF83033.1 - 0.0003 18.4 0.1 0.00034 18.3 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal DUF1989 PF09347.5 AIF83033.1 - 0.016 14.6 1.2 0.084 12.3 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1989) UPF0184 PF03670.8 AIF83033.1 - 0.09 12.9 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) GDH_N PF12466.3 AIF83034.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Archaeal_AmoA PF12942.2 AIF83036.1 - 2.5e-106 353.3 10.8 3e-106 353.0 7.5 1.0 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) FlgD_ig PF13860.1 AIF83038.1 - 0.0011 18.7 0.7 0.0036 17.0 0.1 2.2 2 1 0 2 2 2 1 FlgD Ig-like domain DUF2436 PF10365.4 AIF83038.1 - 0.0032 17.1 0.1 0.048 13.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2436) DUF3108 PF11306.3 AIF83038.1 - 0.0042 16.7 0.1 0.046 13.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3108) He_PIG PF05345.7 AIF83038.1 - 2.6 8.1 7.6 1.3 9.0 0.2 3.6 3 1 0 3 3 3 0 Putative Ig domain Cys_rich_CPCC PF14206.1 AIF83041.1 - 0.015 14.8 1.3 0.062 12.8 0.2 2.1 2 0 0 2 2 2 0 Cysteine-rich CPCC Zn_ribbon_recom PF13408.1 AIF83041.1 - 0.15 12.3 0.8 0.15 12.3 0.6 2.0 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain UDPG_MGDP_dh_N PF03721.9 AIF83043.1 - 1.8e-36 125.2 0.0 1.2e-35 122.5 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 AIF83043.1 - 7.9e-22 77.4 0.0 3.6e-21 75.2 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 AIF83043.1 - 5.6e-21 74.5 0.0 1.4e-20 73.2 0.0 1.7 2 0 0 2 2 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 AIF83043.1 - 3.5e-06 26.8 0.1 0.081 12.6 0.0 2.5 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 AIF83043.1 - 8.3e-05 21.8 0.1 0.0015 17.7 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AIF83043.1 - 0.00013 21.6 0.0 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 AIF83043.1 - 0.00059 19.8 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.10 AIF83043.1 - 0.0013 18.5 0.1 0.0071 16.2 0.0 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AIF83043.1 - 0.0019 18.5 0.7 0.9 10.0 0.0 3.4 3 1 1 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 AIF83043.1 - 0.0098 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 AIF83043.1 - 0.011 16.3 0.0 0.097 13.2 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain NAD_binding_7 PF13241.1 AIF83043.1 - 0.039 14.1 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Androgen_recep PF02166.11 AIF83043.1 - 0.069 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Androgen receptor Methyltransf_31 PF13847.1 AIF83043.1 - 0.14 11.7 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 AIF83043.1 - 0.31 10.8 1.6 3.7 7.3 0.2 2.5 2 0 0 2 2 2 0 ThiF family IF-2B PF01008.12 AIF83044.1 - 3.2e-91 305.2 0.1 3.8e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF59 PF01883.14 AIF83045.1 - 1.4e-15 57.0 0.1 3.2e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 PqqD PF05402.7 AIF83045.1 - 1.3e-08 34.7 0.1 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) Methyltransf_4 PF02390.12 AIF83046.1 - 2.9e-10 39.5 0.0 3.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AIF83046.1 - 5.5e-07 29.6 0.0 7.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83046.1 - 4.1e-06 27.1 0.0 6.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF83046.1 - 1.4e-05 24.7 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF83046.1 - 4e-05 24.1 0.0 6.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AIF83046.1 - 0.0034 16.7 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 AIF83046.1 - 0.0036 17.7 0.0 0.0059 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF83046.1 - 0.013 15.8 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 AIF83046.1 - 0.075 13.8 0.0 0.15 12.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain HTH_45 PF14947.1 AIF83047.1 - 3.4e-12 46.0 0.0 4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.1 AIF83047.1 - 0.095 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 AIF83047.1 - 0.099 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF342 PF03961.8 AIF83048.1 - 5.6e-06 25.0 26.6 3.9e-05 22.2 7.5 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF342) YabP PF07873.6 AIF83048.1 - 0.04 13.4 0.3 5.1 6.7 0.0 3.2 3 0 0 3 3 3 0 YabP family LEA_2 PF03168.8 AIF83048.1 - 0.46 10.9 2.2 1.6 9.1 0.2 2.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein MFS_1 PF07690.11 AIF83049.1 - 3e-55 187.3 73.7 7e-50 169.6 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AIF83049.1 - 2e-14 52.8 37.2 4.4e-09 35.2 8.6 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 AIF83049.1 - 3.9e-06 25.7 16.0 3.9e-06 25.7 11.1 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 AIF83049.1 - 4.3e-05 23.2 1.9 4.3e-05 23.2 1.3 2.4 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.8 AIF83049.1 - 0.021 12.9 28.9 0.0024 16.0 16.6 1.6 1 1 1 2 2 2 0 Transmembrane secretion effector AHSA1 PF08327.6 AIF83051.1 - 5.4e-21 74.9 0.1 7.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 AIF83051.1 - 1.1e-06 28.9 0.3 1.5e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF83051.1 - 0.13 12.2 0.5 0.28 11.1 0.4 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Arginase PF00491.16 AIF83052.1 - 5.9e-38 130.7 0.0 7.2e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family HTH_20 PF12840.2 AIF83053.1 - 6.7e-13 48.2 0.5 9.7e-13 47.7 0.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF83053.1 - 6.6e-06 25.7 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF2513 PF10711.4 AIF83053.1 - 0.065 13.3 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) DUF3860 PF12976.2 AIF83053.1 - 0.083 12.6 0.0 0.17 11.7 0.0 1.6 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) AHSA1 PF08327.6 AIF83054.1 - 8.6e-11 42.0 0.0 9.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein PEGSRP PF07623.6 AIF83055.1 - 0.014 14.6 0.1 0.026 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) zf-FCS PF06467.9 AIF83055.1 - 0.021 14.4 9.1 0.058 13.0 6.3 1.8 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif tRNA-synt_2b PF00587.20 AIF83056.1 - 3.2e-47 160.3 0.1 5.6e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AIF83056.1 - 4e-17 61.9 0.0 9.2e-17 60.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain zf-C3HC PF07967.8 AIF83056.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 C3HC zinc finger-like zinc_ribbon_5 PF13719.1 AIF83056.1 - 1.8 8.2 5.6 0.68 9.5 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Aminotran_1_2 PF00155.16 AIF83057.1 - 6.5e-60 202.9 0.0 7.4e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AIF83057.1 - 9e-06 24.9 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 AIF83057.1 - 1.2e-05 24.2 0.0 2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIF83057.1 - 7.3e-05 22.0 0.0 0.00012 21.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AIF83057.1 - 0.0003 19.1 0.0 0.00056 18.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MRP-S31 PF15433.1 AIF83058.1 - 0.44 9.9 4.3 0.48 9.7 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 VASP_tetra PF08776.6 AIF83059.1 - 0.081 12.2 1.7 3.7 6.9 0.1 2.0 1 1 1 2 2 2 0 VASP tetramerisation domain DUF308 PF03729.8 AIF83060.1 - 0.0033 17.3 3.2 0.061 13.3 0.1 2.7 2 1 1 3 3 3 1 Short repeat of unknown function (DUF308) BacA PF02673.13 AIF83060.1 - 0.02 14.1 0.0 0.026 13.7 0.0 1.4 1 1 0 1 1 1 0 Bacitracin resistance protein BacA Pox_A14 PF05767.7 AIF83060.1 - 0.028 14.3 2.3 0.2 11.6 1.6 2.0 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF1469 PF07332.6 AIF83060.1 - 0.21 11.3 1.6 0.63 9.7 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) DUF204 PF02659.10 AIF83060.1 - 0.38 10.9 3.8 0.5 10.5 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF Gram_pos_anchor PF00746.16 AIF83060.1 - 0.63 9.9 2.3 3.9 7.4 0.2 2.2 2 0 0 2 2 2 0 Gram positive anchor F420_oxidored PF03807.12 AIF83061.1 - 5.2e-14 52.4 0.0 9.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 AIF83061.1 - 2.9e-05 23.8 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.12 AIF83061.1 - 0.0066 15.3 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase 3HCDH_N PF02737.13 AIF83061.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain His_Phos_1 PF00300.17 AIF83062.1 - 4e-29 101.7 0.0 4.8e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Yip1 PF04893.12 AIF83063.1 - 0.0014 18.1 1.6 0.0018 17.8 1.1 1.0 1 0 0 1 1 1 1 Yip1 domain Virul_fac_BrkB PF03631.10 AIF83063.1 - 0.0076 15.6 0.6 0.0094 15.3 0.4 1.0 1 0 0 1 1 1 1 Virulence factor BrkB DUF2500 PF10694.4 AIF83063.1 - 0.012 15.5 0.2 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) MpPF26 PF07666.6 AIF83063.1 - 0.037 13.9 0.1 0.047 13.5 0.1 1.1 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF1049 PF06305.6 AIF83063.1 - 0.047 13.1 0.1 0.047 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1191 PF06697.7 AIF83063.1 - 0.1 11.3 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Dicty_CAR PF05462.6 AIF83063.1 - 0.11 11.3 0.6 0.13 11.1 0.4 1.0 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor DUF1129 PF06570.6 AIF83063.1 - 0.13 11.5 1.7 0.45 9.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF3311 PF11755.3 AIF83063.1 - 0.89 9.1 7.7 4 7.0 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3311) COX2 PF00116.15 AIF83064.1 - 1.6e-22 79.5 0.5 2.4e-20 72.5 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.1 AIF83064.1 - 0.00057 19.7 0.0 0.00069 19.4 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain COX1 PF00115.15 AIF83065.1 - 1.1e-141 472.5 64.1 1.4e-141 472.1 44.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Copper-bind PF00127.15 AIF83066.1 - 1e-13 51.3 0.5 2.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF83066.1 - 1.1e-13 51.0 0.2 5.6e-09 35.8 0.0 2.7 2 2 0 2 2 2 2 Cupredoxin-like domain Phage_30_8 PF06019.6 AIF83066.1 - 0.14 11.8 0.0 0.97 9.1 0.0 2.0 2 0 0 2 2 2 0 Phage GP30.8 protein COX15-CtaA PF02628.10 AIF83067.1 - 1.9e-27 95.9 6.8 2.4e-27 95.5 4.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF420 PF04238.7 AIF83067.1 - 0.0016 18.4 5.4 0.026 14.4 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF420) DUF4079 PF13301.1 AIF83067.1 - 0.024 14.6 6.6 0.027 14.4 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2231 PF09990.4 AIF83067.1 - 0.14 12.5 5.5 0.11 12.9 2.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF4203 PF13886.1 AIF83067.1 - 0.22 10.9 10.4 0.015 14.7 3.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) Cytochrom_B561 PF03188.11 AIF83067.1 - 0.48 10.2 6.3 1.3 8.8 4.4 1.8 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 HCV_NS4a PF01006.15 AIF83067.1 - 0.89 9.1 4.4 13 5.4 0.7 2.7 2 1 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a COPI_assoc PF08507.5 AIF83068.1 - 0.0093 15.6 1.4 0.72 9.5 0.1 2.7 2 1 0 2 2 2 2 COPI associated protein SKG6 PF08693.5 AIF83068.1 - 0.023 13.9 0.2 0.077 12.3 0.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3816 PF12822.2 AIF83068.1 - 0.11 12.3 8.2 0.15 11.9 3.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Acyl_transf_3 PF01757.17 AIF83068.1 - 0.77 8.5 8.2 0.094 11.5 1.6 2.2 2 1 1 3 3 3 0 Acyltransferase family Cyto_ox_2 PF02322.10 AIF83068.1 - 0.95 8.5 9.5 0.059 12.5 1.9 2.1 2 1 0 2 2 2 0 Cytochrome oxidase subunit II Fe-ADH PF00465.14 AIF83069.1 - 3.7e-51 173.8 0.0 1.3e-50 172.1 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 AIF83069.1 - 1.8e-17 63.5 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase UPF0261 PF06792.6 AIF83069.1 - 0.19 10.1 0.2 0.28 9.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Polyketide_cyc2 PF10604.4 AIF83070.1 - 9.9e-11 41.9 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF83070.1 - 6.1e-08 32.7 0.0 9.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 AIF83070.1 - 2.7e-07 30.6 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF217 PF02697.9 AIF83070.1 - 0.0014 18.8 0.2 0.0035 17.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized ACR, COG1753 SGL PF08450.7 AIF83071.1 - 7.4e-08 32.0 1.2 0.0012 18.3 0.0 3.4 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 AIF83071.1 - 1e-06 28.6 6.7 0.032 14.2 0.0 5.9 6 0 0 6 6 6 1 Arylesterase Lactonase PF10282.4 AIF83071.1 - 1.5e-06 27.5 1.4 0.0079 15.3 0.4 3.3 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 AIF83071.1 - 0.00073 17.9 6.5 0.028 12.7 0.9 3.3 1 1 3 4 4 4 3 Cytochrome D1 heme domain NHL PF01436.16 AIF83071.1 - 0.0042 16.9 11.7 1.9 8.6 0.0 6.2 8 0 0 8 8 8 1 NHL repeat DUF4369 PF14289.1 AIF83071.1 - 0.25 11.3 4.3 2.6 8.0 0.2 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4369) NST1 PF13945.1 AIF83072.1 - 0.22 11.5 1.3 0.23 11.5 0.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator RskA PF10099.4 AIF83073.1 - 0.088 12.5 1.1 0.13 12.0 0.8 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TetR_N PF00440.18 AIF83074.1 - 1.1e-17 63.4 0.3 2.4e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.1 AIF83074.1 - 2.3e-12 46.9 0.6 5.9e-12 45.6 0.1 2.0 2 0 0 2 2 2 1 Bacterial transcriptional repressor TetR_C_2 PF08361.6 AIF83074.1 - 0.0067 16.3 0.1 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 MAATS-type transcriptional repressor, C-terminal region Coat_F PF07875.7 AIF83074.1 - 0.045 13.8 0.8 0.44 10.6 0.0 2.6 3 0 0 3 3 3 0 Coat F domain TetR PF13972.1 AIF83074.1 - 0.074 12.4 0.1 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF3353 PF11833.3 AIF83075.1 - 0.031 13.7 0.3 0.031 13.7 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) DUF4229 PF14012.1 AIF83076.1 - 0.022 14.6 2.0 0.022 14.6 1.4 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4229) DUF1275 PF06912.6 AIF83076.1 - 0.21 10.7 6.5 0.69 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF1326 PF07040.6 AIF83077.1 - 3.2e-59 199.7 0.4 3.7e-59 199.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1326) TruB-C_2 PF09157.6 AIF83077.1 - 0.15 11.9 0.1 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal PepSY PF03413.14 AIF83078.1 - 0.00012 22.6 0.6 0.00017 22.1 0.4 1.5 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain Oleosin PF01277.12 AIF83078.1 - 5.9 6.4 6.2 0.42 10.1 1.0 1.5 2 0 0 2 2 2 0 Oleosin DUF4367 PF14285.1 AIF83079.1 - 0.0013 18.0 0.0 1.3 8.3 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4367) GSDH PF07995.6 AIF83081.1 - 6.2e-69 232.5 0.1 2.1e-55 188.0 0.3 2.2 2 0 0 2 2 2 2 Glucose / Sorbosone dehydrogenase NHL PF01436.16 AIF83081.1 - 0.00097 18.9 0.1 0.049 13.6 0.0 3.5 3 0 0 3 3 3 1 NHL repeat Lactonase PF10282.4 AIF83081.1 - 0.0076 15.3 0.0 1.2 8.0 0.0 2.7 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 AIF83081.1 - 0.026 13.8 0.2 14 4.9 0.0 3.7 2 1 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Tachylectin PF14517.1 AIF83081.1 - 0.03 13.6 0.0 0.31 10.3 0.0 2.5 3 0 0 3 3 3 0 Tachylectin PD40 PF07676.7 AIF83081.1 - 0.08 12.6 0.4 1.4 8.6 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Tox-WTIP PF15654.1 AIF83083.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif HEM4 PF02602.10 AIF83084.1 - 6.2e-43 146.6 0.1 7.2e-43 146.4 0.1 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Nitro_FeMo-Co PF02579.12 AIF83084.1 - 0.052 13.6 0.2 3.5 7.7 0.0 3.0 3 1 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor NMT1 PF09084.6 AIF83084.1 - 0.057 12.9 0.0 0.41 10.2 0.0 2.4 2 1 1 3 3 3 0 NMT1/THI5 like TP_methylase PF00590.15 AIF83085.1 - 4.6e-47 160.4 0.2 5.4e-47 160.2 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ApbA PF02558.11 AIF83085.1 - 0.046 13.1 0.1 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3155 PF11352.3 AIF83085.1 - 0.058 13.6 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) Porphobil_deam PF01379.15 AIF83086.1 - 2.1e-74 249.0 0.3 3.3e-74 248.4 0.2 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 AIF83086.1 - 4.3e-18 65.1 0.4 1.7e-17 63.3 0.1 2.1 3 0 0 3 3 3 1 Porphobilinogen deaminase, C-terminal domain LysR_substrate PF03466.15 AIF83086.1 - 2.9e-05 23.2 0.0 0.026 13.6 0.0 3.2 3 0 0 3 3 3 2 LysR substrate binding domain YfdX PF10938.3 AIF83086.1 - 0.00075 19.1 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 YfdX protein DUF4258 PF14076.1 AIF83086.1 - 0.031 14.2 0.0 0.16 11.9 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4258) PAS_4 PF08448.5 AIF83086.1 - 0.11 12.4 0.0 1.3 9.1 0.0 2.4 3 0 0 3 3 3 0 PAS fold Aminotran_3 PF00202.16 AIF83087.1 - 6.7e-62 209.3 0.2 8e-62 209.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AIF83087.1 - 2.6e-09 36.5 0.0 3.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3108 PF11306.3 AIF83089.1 - 1.2e-06 28.3 2.4 9.8e-06 25.3 1.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3108) BBS2_Mid PF14783.1 AIF83089.1 - 0.1 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region EVE PF01878.13 AIF83090.1 - 2.3e-39 134.6 0.2 2.6e-39 134.4 0.2 1.0 1 0 0 1 1 1 1 EVE domain TruD PF01142.13 AIF83091.1 - 2.2e-58 197.7 0.0 2.6e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) HTH_45 PF14947.1 AIF83092.1 - 1.3e-07 31.2 0.2 1.8e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 AIF83092.1 - 0.00064 19.3 0.1 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF83092.1 - 0.0017 18.0 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 AIF83092.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Me-amine-dh_L PF02975.9 AIF83094.1 - 0.0021 18.0 0.5 0.0029 17.5 0.3 1.3 1 0 0 1 1 1 1 Methylamine dehydrogenase, L chain Cys_rich_CPCC PF14206.1 AIF83094.1 - 0.045 13.3 0.8 0.045 13.3 0.5 2.1 2 1 0 2 2 2 0 Cysteine-rich CPCC SPASM PF13186.1 AIF83094.1 - 1.5 9.1 8.2 0.92 9.8 4.2 1.8 1 1 1 2 2 2 0 Iron-sulfur cluster-binding domain Trypsin_2 PF13365.1 AIF83095.1 - 7.2e-23 80.8 0.7 1.6e-22 79.7 0.5 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 AIF83095.1 - 1.6e-16 60.6 0.8 2.7e-16 59.8 0.2 1.7 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 AIF83095.1 - 8.9e-16 57.5 0.6 1e-14 54.1 0.1 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 AIF83095.1 - 0.00059 19.9 1.0 1 9.5 0.0 3.7 3 1 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 AIF83095.1 - 0.0039 16.9 1.4 0.015 15.0 0.0 2.6 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 AIF83095.1 - 0.0065 14.9 1.6 0.089 11.1 0.4 2.2 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S29 PF02907.10 AIF83095.1 - 0.023 14.2 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Cas_Cas4 PF01930.12 AIF83096.1 - 0.00023 21.0 0.1 0.00035 20.5 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function DUF83 Bmp PF02608.9 AIF83097.1 - 0.048 12.3 0.4 0.049 12.3 0.3 1.1 1 0 0 1 1 1 0 Basic membrane protein CBM_15 PF03426.9 AIF83097.1 - 0.077 12.3 0.1 0.081 12.2 0.1 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) LEA_2 PF03168.8 AIF83098.1 - 0.0028 18.0 0.4 0.0076 16.6 0.3 1.8 1 1 0 1 1 1 1 Late embryogenesis abundant protein Gp5_C PF06715.7 AIF83098.1 - 0.84 9.6 6.8 2.7 8.1 0.1 3.6 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) AA_kinase PF00696.23 AIF83100.1 - 1.1e-31 110.1 2.0 1.4e-31 109.9 1.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family TatD_DNase PF01026.16 AIF83100.1 - 0.066 12.3 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase HD PF01966.17 AIF83101.1 - 2.2e-13 50.2 0.3 5e-13 49.1 0.2 1.7 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 AIF83101.1 - 0.0067 15.7 0.1 0.013 14.7 0.1 1.5 1 0 0 1 1 1 1 HDOD domain Thymidylate_kin PF02223.12 AIF83102.1 - 2.5e-32 111.7 0.0 2.9e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 AIF83102.1 - 0.014 16.1 0.1 0.029 15.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AIF83102.1 - 0.022 13.8 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 AIF83102.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 AIF83102.1 - 0.033 13.8 0.0 0.08 12.5 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein UPF0079 PF02367.12 AIF83102.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RecA PF00154.16 AIF83102.1 - 0.063 12.3 0.1 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DUF374 PF04028.8 AIF83102.1 - 0.068 12.4 0.1 6.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF374) AAA_18 PF13238.1 AIF83102.1 - 0.086 13.1 0.2 0.3 11.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain DUF1610 PF07754.6 AIF83104.1 - 0.00082 19.4 20.1 0.082 13.0 2.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.2 AIF83104.1 - 0.0094 15.7 18.7 1.1 9.1 12.9 2.4 1 1 0 1 1 1 1 Transposase zinc-ribbon domain zf-C3HC4_3 PF13920.1 AIF83104.1 - 0.011 15.4 10.1 0.17 11.5 0.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_3 PF07649.7 AIF83104.1 - 0.011 15.7 12.8 0.14 12.2 1.6 2.5 2 1 0 2 2 2 0 C1-like domain DZR PF12773.2 AIF83104.1 - 0.032 14.0 14.2 2.5 7.9 9.8 2.5 1 1 0 1 1 1 0 Double zinc ribbon Yeast-kill-tox PF09207.6 AIF83104.1 - 0.037 14.4 1.8 0.043 14.2 1.2 1.1 1 0 0 1 1 1 0 Yeast killer toxin zf-HIT PF04438.11 AIF83104.1 - 0.044 13.4 5.2 0.044 13.4 3.6 2.9 2 1 0 2 2 2 0 HIT zinc finger Rubredoxin PF00301.15 AIF83104.1 - 0.072 12.9 15.7 0.31 10.9 1.5 3.8 1 1 2 3 3 3 0 Rubredoxin HypA PF01155.14 AIF83104.1 - 0.1 12.3 11.4 0.12 12.0 3.7 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 AIF83104.1 - 0.1 12.3 13.3 0.98 9.1 1.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain RE_MamI PF09567.5 AIF83104.1 - 0.11 11.5 1.6 0.085 11.9 0.4 1.3 1 1 1 2 2 2 0 MamI restriction endonuclease OrfB_Zn_ribbon PF07282.6 AIF83104.1 - 0.12 11.9 14.2 0.37 10.4 1.6 2.8 1 1 2 3 3 3 0 Putative transposase DNA-binding domain Sgf11 PF08209.6 AIF83104.1 - 0.15 11.3 15.1 0.67 9.3 0.1 3.8 3 1 1 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-MYND PF01753.13 AIF83104.1 - 0.16 11.8 0.4 0.16 11.8 0.3 2.3 1 1 0 2 2 2 0 MYND finger PolC_DP2 PF03833.8 AIF83104.1 - 0.17 9.5 7.1 0.17 9.5 4.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.1 AIF83104.1 - 0.21 10.8 0.8 0.21 10.8 0.5 3.3 3 1 0 3 3 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 AIF83104.1 - 0.3 11.1 10.7 0.1 12.6 1.5 2.4 2 1 0 2 2 2 0 zinc-finger ZZ PF00569.12 AIF83104.1 - 0.87 9.1 13.9 12 5.5 2.4 3.4 3 1 0 3 3 3 0 Zinc finger, ZZ type Prok-RING_1 PF14446.1 AIF83104.1 - 0.9 9.3 14.0 11 5.8 5.3 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 CpXC PF14353.1 AIF83104.1 - 1 9.3 11.3 2.4 8.1 0.6 3.1 1 1 2 3 3 3 0 CpXC protein PhnA_Zn_Ribbon PF08274.7 AIF83104.1 - 1.2 9.0 14.9 6.6 6.6 0.5 3.9 3 1 1 4 4 4 0 PhnA Zinc-Ribbon Opy2 PF09463.5 AIF83104.1 - 1.5 8.9 11.4 3 8.0 0.1 3.0 3 0 0 3 3 3 0 Opy2 protein Zn-ribbon_8 PF09723.5 AIF83104.1 - 1.6 8.7 20.5 1.4 8.9 0.7 3.8 1 1 1 3 3 3 0 Zinc ribbon domain PHD PF00628.24 AIF83104.1 - 2.1 8.1 16.4 51 3.6 6.8 3.8 1 1 0 1 1 1 0 PHD-finger TerY-C PF15616.1 AIF83104.1 - 2.1 8.2 12.6 7.4 6.5 8.8 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain zf-Mss51 PF13824.1 AIF83104.1 - 2.1 8.2 12.7 1.7 8.5 1.3 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Elf1 PF05129.8 AIF83104.1 - 2.3 7.9 11.9 1.1 9.0 4.4 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-B_box PF00643.19 AIF83104.1 - 2.3 8.1 12.4 21 5.0 5.5 2.9 2 1 0 2 2 2 0 B-box zinc finger Desulfoferrod_N PF06397.7 AIF83104.1 - 3.2 7.2 13.0 3.7 7.0 0.2 3.4 1 1 3 4 4 4 0 Desulfoferrodoxin, N-terminal domain Tnp_zf-ribbon_2 PF13842.1 AIF83104.1 - 3.3 8.2 14.3 2 8.8 1.8 3.1 2 1 1 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DUF1272 PF06906.6 AIF83104.1 - 3.4 7.5 11.9 41 4.1 8.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) RNHCP PF12647.2 AIF83104.1 - 6.2 6.7 11.4 5.7 6.8 4.3 2.3 1 1 1 2 2 2 0 RNHCP domain DUF35_N PF12172.3 AIF83104.1 - 7.2 6.6 14.6 8.1 6.4 0.1 3.9 2 1 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NOB1_Zn_bind PF08772.6 AIF83104.1 - 8.2 6.3 12.2 21 5.0 3.9 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_1 PF00130.17 AIF83104.1 - 9.3 6.0 13.1 6.2e+02 0.2 9.1 2.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 AIF83104.1 - 9.7 5.9 11.6 5 6.8 1.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_4 PF07975.7 AIF83104.1 - 9.8 6.2 13.2 1.2e+02 2.8 4.9 3.0 1 1 1 2 2 2 0 TFIIH C1-like domain HSP20 PF00011.16 AIF83105.1 - 5.7e-10 38.9 0.0 7.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ABC1 PF03109.11 AIF83106.1 - 5.1e-23 81.2 0.0 1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 AIF83106.1 - 0.029 14.1 0.8 0.17 11.5 0.5 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.6 AIF83106.1 - 0.031 13.4 0.1 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) OmpA_membrane PF01389.12 AIF83107.1 - 0.046 13.2 0.3 0.065 12.7 0.2 1.2 1 0 0 1 1 1 0 OmpA-like transmembrane domain NUDIX PF00293.23 AIF83108.1 - 2.5e-15 56.2 0.0 3.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ComA PF02679.10 AIF83109.1 - 6.1e-49 166.2 0.2 8.8e-49 165.7 0.2 1.2 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) MarR_2 PF12802.2 AIF83109.1 - 2.1e-05 24.0 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF83109.1 - 0.004 16.8 0.1 0.0099 15.5 0.1 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB AP_endonuc_2 PF01261.19 AIF83109.1 - 0.012 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel MarR PF01047.17 AIF83109.1 - 0.025 14.2 0.1 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 MarR family NMT1_2 PF13379.1 AIF83110.1 - 1.1e-35 123.2 0.0 1.4e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.6 AIF83110.1 - 6.2e-13 48.8 0.0 9.6e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 AIF83110.1 - 2.9e-08 33.4 0.0 6.1e-07 29.0 0.0 2.2 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 AIF83110.1 - 7.3e-05 22.1 0.0 0.00037 19.7 0.0 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 B5 PF03484.10 AIF83110.1 - 0.011 15.4 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase B5 domain BPD_transp_1 PF00528.17 AIF83111.1 - 6.5e-18 64.9 18.1 6.5e-18 64.9 12.5 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Pterin_4a PF01329.14 AIF83112.1 - 1e-32 111.7 0.2 1.1e-32 111.6 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase SKG6 PF08693.5 AIF83113.1 - 0.037 13.3 0.1 0.037 13.3 0.1 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF202 PF02656.10 AIF83113.1 - 1 9.6 4.2 17 5.7 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF1469 PF07332.6 AIF83113.1 - 3.3 7.4 6.1 5.4 6.7 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2946 PF11162.3 AIF83114.1 - 0.084 13.0 0.3 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TRAP_alpha PF03896.11 AIF83114.1 - 5 6.0 6.9 1 8.3 2.6 1.4 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4244 PF14029.1 AIF83115.1 - 8.9 5.4 6.8 0.54 9.3 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) DnaJ_CXXCXGXG PF00684.14 AIF83117.1 - 0.0044 17.0 11.7 0.012 15.6 8.1 1.7 1 1 0 1 1 1 1 DnaJ central domain PsaL PF02605.10 AIF83118.1 - 0.11 12.0 3.2 0.36 10.3 0.5 2.4 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI DUF3169 PF11368.3 AIF83118.1 - 2.3 7.3 10.2 0.76 8.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Gly-zipper_OmpA PF13436.1 AIF83118.1 - 2.7 7.6 6.8 3.3 7.4 1.4 2.7 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Tautomerase PF01361.16 AIF83119.1 - 1.7e-15 56.3 0.1 2e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 AIF83119.1 - 1.2e-11 44.4 0.1 1.2e-11 44.4 0.1 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Ribosomal_S6 PF01250.12 AIF83119.1 - 0.0065 16.2 0.1 0.007 16.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 DUF2118 PF09891.4 AIF83119.1 - 0.088 12.5 0.1 0.1 12.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) NCU-G1 PF15065.1 AIF83120.1 - 0.062 11.9 0.3 0.076 11.6 0.2 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 L6_membrane PF05805.7 AIF83120.1 - 0.064 12.7 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 L6 membrane protein RskA PF10099.4 AIF83120.1 - 0.071 12.8 2.0 0.15 11.7 1.4 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA IncA PF04156.9 AIF83120.1 - 0.56 9.7 4.4 2 7.9 0.5 2.2 2 0 0 2 2 2 0 IncA protein Peptidase_M20 PF01546.23 AIF83121.1 - 1.9e-31 109.0 0.0 3e-31 108.3 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIF83121.1 - 1.4e-15 57.0 0.0 2.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Copper-bind PF00127.15 AIF83122.1 - 1e-07 32.0 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF83122.1 - 4.5e-05 23.2 0.0 6.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Cupredoxin-like domain DUF1968 PF09291.5 AIF83122.1 - 0.07 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) Col_cuticle_N PF01484.12 AIF83123.1 - 0.39 10.4 2.6 0.59 9.8 1.8 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain ATP-grasp_5 PF13549.1 AIF83124.1 - 1.9e-84 282.3 0.3 3.7e-84 281.3 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 AIF83124.1 - 4.7e-54 181.7 1.5 4.7e-54 181.7 1.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AIF83124.1 - 3.3e-23 82.0 0.2 3.2e-21 75.6 0.0 3.5 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.14 AIF83124.1 - 1.2e-13 51.4 3.0 1.9e-13 50.7 0.5 2.5 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 AIF83124.1 - 9.9e-06 25.0 0.2 2.1e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AIF83124.1 - 4.2e-05 23.3 0.0 9.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AIF83124.1 - 0.0015 17.8 0.1 0.0031 16.8 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain YIEGIA PF14045.1 AIF83124.1 - 0.03 12.9 0.1 0.062 11.9 0.0 1.4 1 0 0 1 1 1 0 YIEGIA protein HATPase_c PF02518.21 AIF83125.1 - 1.8e-22 79.1 0.1 4.3e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF83125.1 - 3.2e-16 59.0 1.0 8.3e-16 57.7 0.7 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 AIF83125.1 - 0.0038 17.0 0.0 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 AIF83125.1 - 0.0096 15.5 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4070 PF13282.1 AIF83125.1 - 0.018 14.5 0.1 0.064 12.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) BioW PF03744.8 AIF83125.1 - 0.12 11.8 2.2 0.11 11.9 0.2 1.9 2 0 0 2 2 2 0 6-carboxyhexanoate--CoA ligase Acetyltransf_1 PF00583.19 AIF83126.1 - 3.1e-15 55.9 0.0 5e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIF83126.1 - 3e-08 33.7 0.0 7.6e-08 32.4 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIF83126.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 AIF83126.1 - 3.3e-07 30.3 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIF83126.1 - 1.5e-06 28.0 0.1 3.2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIF83126.1 - 2.5e-05 24.3 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AIF83126.1 - 0.0041 16.9 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 AIF83126.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DZR PF12773.2 AIF83127.1 - 1.7e-08 34.1 5.1 3.4e-06 26.7 0.2 2.5 2 1 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF83127.1 - 1.2e-07 30.6 5.5 1.2e-07 30.6 3.8 3.0 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF83127.1 - 3.6e-07 29.4 5.7 3.6e-07 29.4 4.0 2.7 3 0 0 3 3 3 1 zinc-ribbon domain PRC PF05239.11 AIF83127.1 - 0.0016 18.2 0.6 0.0027 17.5 0.4 1.4 1 0 0 1 1 1 1 PRC-barrel domain zf-RanBP PF00641.13 AIF83127.1 - 0.0046 16.0 1.2 0.0046 16.0 0.8 2.5 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zinc-ribbons_6 PF07191.7 AIF83127.1 - 0.05 13.3 5.6 12 5.7 0.7 3.3 3 0 0 3 3 3 0 zinc-ribbons Zn-ribbon_8 PF09723.5 AIF83127.1 - 0.077 12.9 14.4 0.94 9.4 0.0 4.2 3 1 1 4 4 4 0 Zinc ribbon domain HupF_HypC PF01455.13 AIF83127.1 - 0.11 12.4 0.3 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 HupF/HypC family UPF0547 PF10571.4 AIF83127.1 - 0.39 10.4 9.4 0.54 10.0 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 GCC2_GCC3 PF07699.8 AIF83127.1 - 0.47 10.0 9.8 0.34 10.5 2.1 2.9 3 0 0 3 3 3 0 GCC2 and GCC3 OrfB_Zn_ribbon PF07282.6 AIF83127.1 - 0.83 9.3 5.4 0.57 9.8 0.2 2.5 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-B_box PF00643.19 AIF83127.1 - 2 8.3 9.6 3.3 7.6 0.4 2.9 3 0 0 3 3 3 0 B-box zinc finger GFA PF04828.9 AIF83127.1 - 2.9 7.9 8.6 12 5.8 0.6 3.9 2 2 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme ABC2_membrane PF01061.19 AIF83128.1 - 1.9e-22 79.4 23.0 1.9e-22 79.4 16.0 1.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AIF83128.1 - 1e-12 47.8 24.6 1e-12 47.8 17.1 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 AIF83128.1 - 1.1e-07 31.2 32.1 2.1e-07 30.3 22.3 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 AIF83128.1 - 3.1e-06 26.2 22.4 4e-06 25.8 15.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.1 AIF83128.1 - 0.0021 17.3 27.5 0.0069 15.7 17.3 2.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 AIF83129.1 - 1.5e-30 106.3 0.0 3e-30 105.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AIF83129.1 - 2e-12 47.7 0.0 2.8e-07 30.7 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AIF83129.1 - 0.0002 20.5 0.0 0.006 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 AIF83129.1 - 0.0004 20.7 0.0 0.00061 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AIF83129.1 - 0.0029 17.0 0.1 0.0059 16.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4162 PF13732.1 AIF83129.1 - 0.012 16.0 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) SRP54 PF00448.17 AIF83129.1 - 0.016 14.6 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.9 AIF83129.1 - 0.019 14.6 1.1 1.6 8.4 0.4 3.0 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 AIF83129.1 - 0.023 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ACT PF01842.20 AIF83129.1 - 0.051 13.0 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 ACT domain Levi_coat PF01819.12 AIF83129.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Levivirus coat protein AAA_30 PF13604.1 AIF83129.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AIF83129.1 - 0.1 12.8 0.2 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AIF83129.1 - 0.11 11.8 0.2 0.24 10.8 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain tRNA_anti-codon PF01336.20 AIF83130.1 - 1.5e-13 50.4 1.8 0.00067 19.4 0.0 3.6 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain GCS2 PF04107.8 AIF83131.1 - 4.1e-07 29.3 0.0 1.1e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Hemerythrin PF01814.18 AIF83131.1 - 0.074 13.2 0.3 0.074 13.2 0.2 2.1 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DEAD_assoc PF08494.6 AIF83132.1 - 1.2e-32 113.1 0.1 2.7e-32 112.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/H associated DEAD PF00270.24 AIF83132.1 - 1.7e-32 112.2 0.3 1.2e-31 109.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIF83132.1 - 1e-19 70.1 0.0 6.4e-18 64.3 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AIF83132.1 - 2e-07 30.1 0.0 1.7e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 AIF83132.1 - 3.6e-06 26.9 0.0 8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zn-ribbon_8 PF09723.5 AIF83132.1 - 0.0057 16.5 0.5 0.012 15.5 0.4 1.6 1 0 0 1 1 1 1 Zinc ribbon domain Cas_APE2256 PF09651.5 AIF83132.1 - 0.022 14.4 0.2 1.5 8.5 0.0 3.4 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_APE2256) AAA_19 PF13245.1 AIF83132.1 - 0.058 13.1 0.1 29 4.4 0.0 3.6 4 0 0 4 4 4 0 Part of AAA domain DUF4428 PF14471.1 AIF83132.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2500 PF10694.4 AIF83133.1 - 0.024 14.6 0.0 0.025 14.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF1049 PF06305.6 AIF83133.1 - 0.034 13.6 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) IncA PF04156.9 AIF83133.1 - 0.038 13.5 0.0 0.041 13.4 0.0 1.0 1 0 0 1 1 1 0 IncA protein DUF3357 PF11837.3 AIF83133.1 - 0.038 13.8 0.1 0.044 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF1191 PF06697.7 AIF83133.1 - 0.059 12.1 0.0 0.061 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 AIF83133.1 - 0.084 13.2 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AIF_C PF14721.1 AIF83133.1 - 0.1 12.8 0.1 0.11 12.7 0.1 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Phage_holin_3 PF05106.7 AIF83135.1 - 0.021 14.8 0.4 0.021 14.8 0.3 2.1 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) Tic20 PF09685.5 AIF83135.1 - 0.042 13.8 0.3 0.042 13.8 0.2 2.4 2 1 0 2 2 2 0 Tic20-like protein Fzo_mitofusin PF04799.8 AIF83136.1 - 0.017 14.4 1.3 0.023 14.0 0.9 1.2 1 0 0 1 1 1 0 fzo-like conserved region DoxX_3 PF13781.1 AIF83136.1 - 0.14 12.5 3.5 0.54 10.6 0.1 2.1 1 1 0 2 2 2 0 DoxX-like family DUF739 PF05339.6 AIF83137.1 - 0.022 14.5 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF739) TrmB PF01978.14 AIF83137.1 - 0.039 13.6 0.2 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AIF83137.1 - 0.049 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF326 PF03860.11 AIF83139.1 - 2.2e-12 46.0 53.0 0.00081 19.0 5.2 4.2 4 0 0 4 4 4 4 Domain of Unknown Function (DUF326) CbiG_C PF01890.11 AIF83139.1 - 0.035 14.3 0.3 0.041 14.1 0.2 1.1 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus zf-C2H2 PF00096.21 AIF83140.1 - 7e-05 22.9 1.1 8.7e-05 22.6 0.8 1.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF83140.1 - 7.7e-05 22.7 0.1 0.0001 22.4 0.1 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 AIF83140.1 - 0.011 15.8 0.2 0.015 15.4 0.2 1.2 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 AIF83140.1 - 0.033 14.0 0.2 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AIF83140.1 - 0.65 10.3 3.8 8 6.9 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double domain LEA_2 PF03168.8 AIF83142.1 - 0.0029 17.9 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Polyketide_cyc2 PF10604.4 AIF83143.1 - 0.011 15.8 0.4 0.014 15.5 0.3 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport TrmB PF01978.14 AIF83144.1 - 2.4e-16 59.2 0.1 6.6e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.11 AIF83144.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Penicillinase repressor MarR_2 PF12802.2 AIF83144.1 - 0.02 14.5 0.1 0.051 13.2 0.0 1.7 2 0 0 2 2 2 0 MarR family FUR PF01475.14 AIF83144.1 - 0.022 14.6 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Ferric uptake regulator family PadR PF03551.9 AIF83144.1 - 0.068 12.9 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Aldo_ket_red PF00248.16 AIF83145.1 - 3.8e-53 180.1 0.0 4.4e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GtrA PF04138.9 AIF83147.1 - 0.13 12.2 4.9 0.24 11.3 3.4 1.4 1 1 0 1 1 1 0 GtrA-like protein tRNA-synt_1b PF00579.20 AIF83148.1 - 1.5e-40 139.1 0.0 3.9e-40 137.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF45 PF01863.12 AIF83149.1 - 3.6e-52 177.1 1.8 4.1e-52 176.9 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.5 AIF83149.1 - 1.1e-06 28.6 0.1 2.1e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.4 AIF83149.1 - 0.0068 16.0 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 SprT-like family DUF2201_N PF13203.1 AIF83149.1 - 0.084 12.0 0.1 0.15 11.2 0.1 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain TP6A_N PF04406.9 AIF83153.1 - 3.2e-13 49.1 0.0 6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 AIF83153.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Topo-VIb_trans PF09239.6 AIF83154.1 - 2.1e-34 118.3 0.1 2.1e-31 108.6 0.1 2.6 1 1 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.21 AIF83154.1 - 5e-10 39.0 0.0 1.4e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AIF83154.1 - 2.7e-08 33.5 0.0 9.2e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rod_cone_degen PF15201.1 AIF83155.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Progressive rod-cone degeneration DUF3237 PF11578.3 AIF83155.1 - 0.059 12.6 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) PQ-loop PF04193.9 AIF83156.1 - 4.2e-11 42.2 0.8 7.3e-11 41.4 0.2 1.7 1 1 1 2 2 2 1 PQ loop repeat MtN3_slv PF03083.11 AIF83156.1 - 1.1e-07 31.6 0.5 1.5e-07 31.1 0.3 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange LAB_N PF07578.6 AIF83156.1 - 0.014 15.3 0.2 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain ER_lumen_recept PF00810.13 AIF83156.1 - 0.13 12.7 0.4 0.18 12.2 0.3 1.2 1 0 0 1 1 1 0 ER lumen protein retaining receptor Rieske PF00355.21 AIF83157.1 - 0.0091 15.5 0.7 0.011 15.3 0.5 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DHO_dh PF01180.16 AIF83159.1 - 9.5e-37 126.5 0.0 1.1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 AIF83159.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase FMN_dh PF01070.13 AIF83159.1 - 0.035 12.9 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Radical_SAM PF04055.16 AIF83160.1 - 1.9e-08 34.6 0.0 4.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Propeptide_C25 PF08126.6 AIF83160.1 - 0.029 13.3 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Propeptide_C25 POR PF01558.13 AIF83160.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase TrbH PF07283.6 AIF83161.1 - 0.0098 15.7 0.1 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Conjugal transfer protein TrbH Mitofilin PF09731.4 AIF83161.1 - 0.017 13.8 0.2 0.02 13.5 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HD PF01966.17 AIF83162.1 - 5e-14 52.3 0.7 8.2e-14 51.6 0.5 1.4 1 0 0 1 1 1 1 HD domain DUF706 PF05153.10 AIF83162.1 - 0.043 13.1 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF706) Monooxygenase_B PF04744.7 AIF83163.1 - 1.6e-08 33.6 0.1 3.4e-08 32.6 0.0 1.4 2 0 0 2 2 2 1 Monooxygenase subunit B protein tRNA_anti-like PF12869.2 AIF83163.1 - 0.023 14.1 0.2 7 6.1 0.2 2.5 2 1 0 2 2 2 0 tRNA_anti-like Rad51 PF08423.6 AIF83164.1 - 3.2e-91 304.7 0.5 4.4e-91 304.3 0.4 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AIF83164.1 - 6.1e-12 45.3 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AIF83164.1 - 2.5e-11 43.2 0.2 3.4e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AIF83164.1 - 7.6e-10 38.2 0.1 1.3e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 AIF83164.1 - 2.2e-05 24.5 0.3 6.5e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.3 AIF83164.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus AAA_22 PF13401.1 AIF83164.1 - 0.0073 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol_lambd_f PF10391.4 AIF83164.1 - 0.13 11.7 0.0 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Ribosomal_L21e PF01157.13 AIF83165.1 - 3.7e-14 52.3 1.7 4.4e-14 52.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_pol_Rpb4 PF03874.11 AIF83166.1 - 1.5e-12 47.5 0.6 3.8e-12 46.2 0.4 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb4 Bse634I PF07832.6 AIF83166.1 - 0.00031 19.9 0.3 0.00034 19.8 0.2 1.0 1 0 0 1 1 1 1 Cfr10I/Bse634I restriction endonuclease HNF-1_N PF04814.8 AIF83166.1 - 0.027 14.5 0.2 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Vitellogenin_N PF01347.17 AIF83166.1 - 0.075 11.2 0.5 0.093 10.9 0.3 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region DUF2624 PF11116.3 AIF83166.1 - 0.078 13.4 0.9 0.28 11.7 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) Glycos_trans_3N PF02885.12 AIF83166.1 - 0.11 12.0 0.1 0.47 10.0 0.0 2.0 1 1 1 2 2 2 0 Glycosyl transferase family, helical bundle domain HTH_37 PF13744.1 AIF83166.1 - 0.14 11.9 0.5 0.4 10.5 0.1 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain Vps4_C PF09336.5 AIF83166.1 - 0.16 11.9 0.5 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF655 PF04919.7 AIF83167.1 - 4.2e-56 189.5 0.3 4.8e-56 189.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.1 AIF83167.1 - 2.9e-05 24.0 0.0 6.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.2 AIF83167.1 - 0.0027 17.6 0.1 0.0059 16.5 0.0 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix motif Transposase_20 PF02371.11 AIF83167.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family RrnaAD PF00398.15 AIF83168.1 - 7.7e-39 133.2 0.0 9e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AIF83168.1 - 5.3e-08 32.9 0.0 8.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF83168.1 - 1.4e-06 27.7 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIF83168.1 - 2.2e-05 24.9 0.0 3.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF83168.1 - 8.5e-05 22.1 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83168.1 - 0.00041 20.7 0.0 0.0013 19.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF83168.1 - 0.0043 16.7 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF83169.1 - 2.4e-09 37.2 0.0 4.5e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF83169.1 - 7.4e-08 31.9 0.0 1.3e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AIF83169.1 - 0.0075 16.8 0.1 0.012 16.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83169.1 - 0.0092 16.4 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF83169.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Eco57I PF07669.6 AIF83169.1 - 0.035 14.4 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Methyltransf_12 PF08242.7 AIF83169.1 - 0.071 13.5 0.1 0.14 12.6 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AIF83169.1 - 0.12 12.7 0.1 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Iso_dh PF00180.15 AIF83170.1 - 7.2e-79 265.2 0.0 8.7e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pox_TAA1 PF03295.9 AIF83170.1 - 0.07 12.7 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal Metallophos_2 PF12850.2 AIF83172.1 - 8.2e-19 67.9 0.0 1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AIF83172.1 - 9e-19 67.6 0.2 1.3e-18 67.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MutL PF13941.1 AIF83172.1 - 0.072 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 MutL protein AmoC PF04896.7 AIF83173.1 - 1.5e-16 60.1 5.5 1.9e-16 59.8 3.8 1.0 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C OAD_gamma PF04277.8 AIF83173.1 - 0.26 11.6 2.0 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain NMN_transporter PF04973.7 AIF83173.1 - 1.4 8.3 8.8 0.98 8.8 4.4 1.9 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter DUF581 PF04570.9 AIF83174.1 - 0.017 14.3 7.5 0.019 14.2 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF581) zf-AN1 PF01428.11 AIF83174.1 - 0.036 13.9 7.0 0.047 13.5 4.9 1.2 1 0 0 1 1 1 0 AN1-like Zinc finger zf-B_box PF00643.19 AIF83174.1 - 0.039 13.8 6.8 0.052 13.4 4.7 1.2 1 0 0 1 1 1 0 B-box zinc finger UPF1_Zn_bind PF09416.5 AIF83174.1 - 0.26 10.8 5.6 0.29 10.6 3.9 1.1 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) zf-UBP PF02148.14 AIF83174.1 - 0.43 10.7 6.3 0.58 10.3 4.4 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Fer4_3 PF12798.2 AIF83174.1 - 0.58 10.8 4.3 4.9 7.9 0.3 2.5 2 1 0 2 2 2 0 4Fe-4S binding domain zf-RING_5 PF14634.1 AIF83174.1 - 0.62 9.8 6.2 0.7 9.6 4.3 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-HIT PF04438.11 AIF83174.1 - 0.98 9.1 9.6 1.6 8.4 6.7 1.5 1 1 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.13 AIF83174.1 - 1.4 8.8 8.4 1.9 8.4 5.8 1.3 1 0 0 1 1 1 0 MYND finger DZR PF12773.2 AIF83174.1 - 1.4 8.7 7.7 2.8 7.8 5.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF329 PF03884.9 AIF83174.1 - 2.7 7.5 6.6 8.9 5.9 4.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF329) C1_2 PF03107.11 AIF83174.1 - 4.7 7.4 9.2 11 6.1 6.4 1.7 1 1 0 1 1 1 0 C1 domain MacB_PCD PF12704.2 AIF83175.1 - 4.6e-28 98.3 0.8 4.6e-28 98.3 0.5 2.3 2 1 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.16 AIF83175.1 - 1.2e-22 79.8 7.2 1.2e-22 79.8 5.0 2.0 2 0 0 2 2 2 1 FtsX-like permease family NPCBM_assoc PF10633.4 AIF83176.1 - 1.6e-08 34.4 10.5 0.034 14.1 0.0 5.5 4 2 0 4 4 4 4 NPCBM-associated, NEW3 domain of alpha-galactosidase Protocadherin PF08374.6 AIF83176.1 - 1.5e-05 24.7 0.2 2.5e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Protocadherin DUF11 PF01345.13 AIF83176.1 - 0.00034 20.5 1.8 0.00034 20.5 1.2 4.2 4 0 0 4 4 4 1 Domain of unknown function DUF11 CARDB PF07705.6 AIF83176.1 - 0.0012 18.9 10.5 0.042 13.8 0.2 4.1 2 2 2 4 4 4 2 CARDB Syndecan PF01034.15 AIF83176.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain P12 PF12669.2 AIF83176.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.7 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF1180 PF06679.7 AIF83176.1 - 0.18 11.6 2.6 2.8 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) ABC_tran PF00005.22 AIF83177.1 - 6.5e-34 117.1 0.0 1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF83177.1 - 1.2e-14 55.0 0.2 4.9e-08 33.2 0.0 2.1 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 AIF83177.1 - 1.1e-07 31.2 0.3 3.6e-06 26.3 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AIF83177.1 - 5.9e-07 28.8 0.0 0.0019 17.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AIF83177.1 - 2.5e-05 23.7 0.1 5.3e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 AIF83177.1 - 0.00023 20.3 0.1 0.00039 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AIF83177.1 - 0.00037 20.5 0.1 0.00049 20.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AIF83177.1 - 0.00039 20.5 0.1 0.0024 18.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AIF83177.1 - 0.0009 19.6 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AIF83177.1 - 0.00095 18.6 0.0 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 AIF83177.1 - 0.0011 19.7 0.0 0.0019 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AIF83177.1 - 0.0017 18.2 0.3 0.0038 17.1 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 AIF83177.1 - 0.0043 16.4 0.0 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIF83177.1 - 0.0074 16.1 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AIF83177.1 - 0.0089 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase IstB_IS21 PF01695.12 AIF83177.1 - 0.0098 15.3 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 AIF83177.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 AIF83177.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AIF83177.1 - 0.011 15.3 0.1 0.035 13.7 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 AIF83177.1 - 0.013 15.1 0.1 0.031 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AIF83177.1 - 0.017 14.8 0.1 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 AIF83177.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AIF83177.1 - 0.056 13.2 0.2 0.78 9.5 0.2 2.1 2 0 0 2 2 2 0 Dynamin family T2SE PF00437.15 AIF83177.1 - 0.068 12.0 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 AIF83177.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.15 AIF83177.1 - 0.078 11.6 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit NTPase_1 PF03266.10 AIF83177.1 - 0.078 12.6 0.1 2.7 7.6 0.0 2.4 2 1 0 2 2 2 0 NTPase ABC_ATPase PF09818.4 AIF83177.1 - 0.11 11.0 0.0 0.35 9.3 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.17 AIF83177.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA12 PF10443.4 AIF83177.1 - 0.11 10.9 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein ATP-synt_ab PF00006.20 AIF83177.1 - 0.12 11.8 0.7 0.21 11.0 0.3 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 AIF83177.1 - 0.13 12.1 0.1 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain YHS PF04945.8 AIF83178.1 - 2.7e-12 46.3 0.7 3.3e-12 46.0 0.5 1.1 1 0 0 1 1 1 1 YHS domain Arc_trans_TRASH PF08394.5 AIF83178.1 - 3.6e-06 27.0 1.3 4.4e-06 26.7 0.9 1.1 1 0 0 1 1 1 1 Archaeal TRASH domain ATPase-cat_bd PF12156.3 AIF83178.1 - 2.6e-05 24.6 1.5 3.2e-05 24.3 1.1 1.0 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase CAP_GLY PF01302.20 AIF83178.1 - 0.022 14.4 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 CAP-Gly domain zf-FCS PF06467.9 AIF83178.1 - 0.027 14.0 1.1 0.031 13.9 0.7 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Lactamase_B_4 PF13691.1 AIF83178.1 - 0.059 12.8 0.1 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 tRNase Z endonuclease Ta0938 PF11494.3 AIF83178.1 - 0.098 12.7 0.2 0.098 12.7 0.1 1.1 1 0 0 1 1 1 0 Ta0938 YwqJ-deaminase PF14431.1 AIF83178.1 - 0.15 11.8 0.4 0.17 11.7 0.3 1.1 1 0 0 1 1 1 0 YwqJ-like deaminase zf-H2C2_2 PF13465.1 AIF83178.1 - 0.8 10.1 3.8 1.3 9.4 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger double domain Asn_synthase PF00733.16 AIF83179.1 - 6.4e-32 111.0 0.4 1.2e-30 106.8 0.3 2.0 1 1 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 AIF83179.1 - 0.04 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 AIF83179.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Glyoxalase_4 PF13669.1 AIF83180.1 - 4.5e-23 81.3 0.0 5.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 AIF83180.1 - 4.5e-14 52.5 0.0 5.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AIF83180.1 - 8.7e-09 35.5 0.0 1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.2 AIF83180.1 - 2.4e-07 31.3 0.0 3.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Fucose_iso_C PF02952.12 AIF83180.1 - 0.045 13.2 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 L-fucose isomerase, C-terminal domain MM_CoA_mutase PF01642.17 AIF83181.1 - 4.5e-198 658.5 0.1 5.1e-198 658.4 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase PAP_PilO PF06864.7 AIF83181.1 - 0.014 13.7 0.0 0.029 12.7 0.0 1.5 2 0 0 2 2 2 0 Pilin accessory protein (PilO) bact-PGI_C PF10432.4 AIF83181.1 - 0.038 13.6 0.1 0.3 10.7 0.1 2.5 3 0 0 3 3 3 0 Bacterial phospho-glucose isomerase C-terminal region ELFV_dehydrog_N PF02812.13 AIF83181.1 - 0.067 12.7 0.1 0.26 10.8 0.1 2.0 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF3037 PF11236.3 AIF83181.1 - 0.082 12.9 3.0 4.5 7.3 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3037) ArgK PF03308.11 AIF83182.1 - 6e-85 284.2 4.6 7.5e-85 283.9 3.2 1.0 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 AIF83182.1 - 5.4e-07 29.2 0.3 9.8e-07 28.3 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 AIF83182.1 - 5.1e-06 26.2 0.0 0.0077 15.8 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein cobW PF02492.14 AIF83182.1 - 0.00054 19.4 0.7 0.0027 17.1 0.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 AIF83182.1 - 0.00078 19.1 0.1 0.0093 15.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 AIF83182.1 - 0.00087 18.7 0.1 0.0064 15.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AIF83182.1 - 0.00099 18.3 0.0 0.0027 16.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AIF83182.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.9 AIF83182.1 - 0.021 13.7 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.1 AIF83182.1 - 0.022 14.3 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AIF83182.1 - 0.047 13.1 0.2 0.1 12.0 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 AIF83182.1 - 0.063 13.5 0.4 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter ArsA_ATPase PF02374.10 AIF83182.1 - 0.066 12.2 2.7 0.29 10.1 0.3 2.3 2 0 0 2 2 2 0 Anion-transporting ATPase SUA5 PF03481.8 AIF83182.1 - 0.091 12.8 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative GTP-binding controlling metal-binding AAA_5 PF07728.9 AIF83182.1 - 0.099 12.3 0.3 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 AIF83182.1 - 0.17 11.8 0.7 1.2 9.1 0.3 2.5 2 1 0 2 2 1 0 50S ribosome-binding GTPase Cas_Cas02710 PF09670.5 AIF83183.1 - 0.003 16.2 0.9 0.0033 16.1 0.6 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Fiji_64_capsid PF05880.6 AIF83183.1 - 0.0052 15.1 0.1 0.0059 15.0 0.1 1.0 1 0 0 1 1 1 1 Fijivirus 64 kDa capsid protein DUF3486 PF11985.3 AIF83183.1 - 0.035 14.1 1.9 0.041 13.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Spore_YhcN_YlaJ PF09580.5 AIF83183.1 - 0.7 9.9 4.8 3.4 7.7 0.1 2.0 1 1 1 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) B12-binding PF02310.14 AIF83184.1 - 3.6e-17 62.3 0.0 4.6e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 B12 binding domain Ocnus PF05005.10 AIF83184.1 - 0.028 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) IlvN PF07991.7 AIF83185.1 - 2.9e-69 231.6 0.8 4e-69 231.2 0.5 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 AIF83185.1 - 7.2e-51 171.9 0.1 1.1e-50 171.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 AIF83185.1 - 2e-07 30.9 0.3 3.8e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AIF83185.1 - 4.9e-07 29.0 0.1 8.5e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AIF83185.1 - 9.4e-06 25.9 0.6 2.1e-05 24.8 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 AIF83185.1 - 0.0042 16.9 0.2 0.0076 16.1 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain tRNA_SAD PF07973.9 AIF83185.1 - 0.16 11.8 0.1 0.42 10.5 0.1 1.6 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Usp PF00582.21 AIF83186.1 - 1.2e-30 106.5 0.1 1.4e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 Universal stress protein family Tox-PL-2 PF15643.1 AIF83186.1 - 0.029 14.3 0.9 0.045 13.7 0.3 1.6 1 1 1 2 2 2 0 Papain fold toxin 2 PGM_PMM_I PF02878.11 AIF83186.1 - 0.094 12.1 0.1 0.43 10.0 0.0 2.0 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Yip1 PF04893.12 AIF83189.1 - 0.0016 17.9 22.8 0.0025 17.3 15.8 1.3 1 0 0 1 1 1 1 Yip1 domain DUF360 PF04020.8 AIF83189.1 - 0.023 15.0 6.0 0.023 15.0 4.1 2.2 1 1 1 2 2 2 0 Membrane protein of unknown function ABC2_membrane_4 PF12730.2 AIF83189.1 - 0.027 13.6 20.0 0.046 12.8 13.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_U4 PF03419.8 AIF83189.1 - 1.9 7.4 8.6 2.9 6.8 6.0 1.3 1 1 0 1 1 1 0 Sporulation factor SpoIIGA HisKA_3 PF07730.8 AIF83190.1 - 5.2e-06 26.7 4.1 0.0014 18.9 0.1 3.3 2 1 1 3 3 3 1 Histidine kinase Laminin_II PF06009.7 AIF83190.1 - 0.0002 21.0 9.3 0.033 13.9 1.2 2.1 1 1 1 2 2 2 2 Laminin Domain II DUF883 PF05957.8 AIF83190.1 - 0.0013 19.0 6.7 0.088 13.2 1.1 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) PhageMin_Tail PF10145.4 AIF83190.1 - 0.0069 16.0 5.3 1.6 8.3 0.0 2.1 1 1 0 1 1 1 1 Phage-related minor tail protein DUF4226 PF10774.4 AIF83190.1 - 0.011 15.7 6.3 0.15 12.0 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) BLOC1_2 PF10046.4 AIF83190.1 - 0.018 15.1 5.5 0.042 13.9 1.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.6 AIF83190.1 - 0.018 12.5 5.3 0.047 11.2 3.2 1.6 1 1 1 2 2 2 0 Prominin DUF1664 PF07889.7 AIF83190.1 - 0.025 14.4 6.6 0.056 13.2 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 AIF83190.1 - 0.025 14.0 2.9 0.025 14.0 2.0 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 YtxH PF12732.2 AIF83190.1 - 0.032 14.5 11.3 2e+02 2.4 7.8 3.1 1 1 0 1 1 1 0 YtxH-like protein WXG100 PF06013.7 AIF83190.1 - 0.033 14.1 5.6 19 5.3 2.1 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG RmuC PF02646.11 AIF83190.1 - 0.038 12.8 4.9 0.058 12.2 0.4 2.3 1 1 2 3 3 3 0 RmuC family Syntaxin_2 PF14523.1 AIF83190.1 - 0.052 13.5 3.5 0.18 11.8 2.4 2.1 1 1 2 3 3 3 0 Syntaxin-like protein DUF241 PF03087.9 AIF83190.1 - 0.053 12.9 2.2 0.1 12.0 1.5 1.4 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DUF948 PF06103.6 AIF83190.1 - 0.056 13.3 7.2 0.2 11.5 2.4 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0564 PF10595.4 AIF83190.1 - 0.072 11.9 5.7 0.088 11.7 3.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 TMP_2 PF06791.8 AIF83190.1 - 0.077 12.6 7.1 0.21 11.1 0.5 2.1 1 1 1 2 2 2 0 Prophage tail length tape measure protein HTH_27 PF13463.1 AIF83190.1 - 0.084 13.2 0.1 2.9 8.2 0.0 2.4 1 1 1 2 2 2 0 Winged helix DNA-binding domain Pox_H7 PF04787.7 AIF83190.1 - 0.087 12.6 2.7 0.12 12.1 0.7 1.8 1 1 1 2 2 2 0 Late protein H7 DUF2250 PF10007.4 AIF83190.1 - 0.096 12.6 1.1 3.3 7.6 0.0 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) TMPIT PF07851.8 AIF83190.1 - 0.096 11.7 3.9 0.46 9.5 0.8 2.0 2 0 0 2 2 2 0 TMPIT-like protein Laminin_I PF06008.9 AIF83190.1 - 0.11 11.8 6.0 0.59 9.4 4.2 2.0 1 1 0 1 1 1 0 Laminin Domain I DUF3141 PF11339.3 AIF83190.1 - 0.12 10.7 0.5 0.14 10.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Antimicrobial_7 PF08102.6 AIF83190.1 - 0.12 12.3 1.3 31 4.6 0.0 3.5 2 1 1 3 3 3 0 Scorpion antimicrobial peptide DUF2203 PF09969.4 AIF83190.1 - 0.14 12.4 5.6 1.3 9.2 1.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) V-SNARE_C PF12352.3 AIF83190.1 - 0.16 12.0 1.7 0.83 9.7 0.1 2.5 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF725 PF05267.7 AIF83190.1 - 0.16 11.8 1.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF725) DASH_Duo1 PF08651.5 AIF83190.1 - 0.17 11.4 2.0 5.8 6.5 0.1 2.6 2 1 0 2 2 2 0 DASH complex subunit Duo1 DUF4208 PF13907.1 AIF83190.1 - 0.17 12.1 1.7 0.65 10.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Init_tRNA_PT PF04179.7 AIF83190.1 - 0.18 10.6 4.7 0.22 10.3 3.3 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase ECM11 PF15463.1 AIF83190.1 - 0.19 11.9 2.3 2.8 8.1 0.1 2.3 2 1 0 2 2 2 0 Extracellular mutant protein 11 Apolipoprotein PF01442.13 AIF83190.1 - 0.25 10.8 4.6 3 7.3 3.2 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Sec8_exocyst PF04048.9 AIF83190.1 - 0.31 10.6 3.5 1.6 8.3 0.4 2.3 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Syntaxin-6_N PF09177.6 AIF83190.1 - 0.32 11.4 6.4 42 4.6 4.4 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4559 PF15112.1 AIF83190.1 - 0.36 9.9 2.4 0.45 9.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) AIP3 PF03915.8 AIF83190.1 - 0.36 9.6 5.8 0.48 9.2 4.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 AAA_13 PF13166.1 AIF83190.1 - 0.63 8.4 7.2 0.82 8.0 5.0 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 AIF83190.1 - 0.69 8.5 8.2 3.7 6.1 5.5 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2580 PF10824.3 AIF83190.1 - 0.76 10.1 4.2 6 7.2 2.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2580) Cauli_DNA-bind PF03310.8 AIF83190.1 - 0.8 9.5 5.7 0.42 10.4 1.7 1.9 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Spectrin PF00435.16 AIF83190.1 - 0.84 9.9 4.4 5.8 7.2 1.3 2.4 1 1 2 3 3 3 0 Spectrin repeat Effector_1 PF04518.7 AIF83190.1 - 1.4 7.7 5.7 1 8.3 2.9 1.5 1 1 0 1 1 1 0 Effector from type III secretion system RRF PF01765.14 AIF83190.1 - 1.9 7.9 12.1 7.2 6.0 3.7 2.6 1 1 1 2 2 2 0 Ribosome recycling factor TPR_MLP1_2 PF07926.7 AIF83190.1 - 2 8.1 8.4 14 5.4 5.8 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 AIF83190.1 - 2.4 7.7 5.1 8.1 5.9 2.8 1.9 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 AIF83190.1 - 2.5 8.3 10.1 76 3.5 6.9 2.7 1 1 0 1 1 1 0 Syntaxin TBPIP PF07106.8 AIF83190.1 - 2.6 7.5 7.1 2.4 7.6 1.5 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlgN PF05130.7 AIF83190.1 - 4.3 7.5 7.4 19 5.4 2.6 2.1 1 1 1 2 2 2 0 FlgN protein Seryl_tRNA_N PF02403.17 AIF83190.1 - 4.7 7.2 10.6 5.9 6.9 3.8 2.6 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_60s PF00428.14 AIF83190.1 - 7.4 7.0 9.7 5.2 7.5 1.8 2.5 1 1 2 3 3 3 0 60s Acidic ribosomal protein ADK_lid PF05191.9 AIF83192.1 - 0.029 14.0 0.9 0.079 12.6 0.6 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-C4pol PF14260.1 AIF83192.1 - 0.068 13.1 0.8 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta SpoIISB_antitox PF14185.1 AIF83192.1 - 0.087 12.5 0.3 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system DZR PF12773.2 AIF83192.1 - 0.13 12.1 0.6 0.26 11.1 0.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 AIF83192.1 - 0.4 10.4 2.8 8.6 6.2 0.1 2.2 1 1 1 2 2 2 0 zinc-ribbons HTH_20 PF12840.2 AIF83193.1 - 2.1e-13 49.8 0.6 4.4e-13 48.8 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF83193.1 - 2.2e-13 49.6 0.4 5.8e-13 48.2 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF83193.1 - 9.8e-09 34.7 0.3 4e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 AIF83193.1 - 4.6e-08 32.3 1.4 8.9e-08 31.4 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AIF83193.1 - 1.2e-05 24.8 0.2 3.2e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.1 AIF83193.1 - 8.4e-05 22.2 0.4 0.0006 19.5 0.1 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.17 AIF83193.1 - 0.00029 20.4 1.5 0.00093 18.8 0.2 2.2 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.1 AIF83193.1 - 0.00054 19.9 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain UPF0172 PF03665.8 AIF83193.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) TrmB PF01978.14 AIF83193.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AIF83193.1 - 0.0028 17.2 0.2 0.006 16.1 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.11 AIF83193.1 - 0.0035 16.5 0.1 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 AIF83193.1 - 0.004 16.3 0.2 0.008 15.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.7 AIF83193.1 - 0.0042 16.6 0.1 0.0083 15.6 0.0 1.5 1 0 0 1 1 1 1 HTH DNA binding domain TFIIE_alpha PF02002.12 AIF83193.1 - 0.0055 16.1 1.0 0.0073 15.8 0.1 1.6 2 0 0 2 2 1 1 TFIIE alpha subunit HTH_26 PF13443.1 AIF83193.1 - 0.008 16.3 0.2 0.02 15.0 0.1 1.7 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Rrf2 PF02082.15 AIF83193.1 - 0.01 15.9 0.2 0.024 14.7 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_23 PF13384.1 AIF83193.1 - 0.018 14.6 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.17 AIF83193.1 - 0.019 14.7 0.1 0.046 13.5 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix HTH_27 PF13463.1 AIF83193.1 - 0.03 14.6 0.9 0.057 13.7 0.1 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.7 AIF83193.1 - 0.041 13.7 0.4 0.1 12.4 0.1 1.9 2 0 0 2 2 1 0 B-block binding subunit of TFIIIC HTH_36 PF13730.1 AIF83193.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.8 AIF83193.1 - 0.051 13.8 0.1 0.19 12.0 0.0 2.1 2 0 0 2 2 1 0 Mga helix-turn-helix domain HTH_9 PF08221.6 AIF83193.1 - 0.058 13.2 0.3 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_AsnC-type PF13404.1 AIF83193.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_37 PF13744.1 AIF83193.1 - 0.11 12.2 0.4 0.52 10.1 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_15 PF12324.3 AIF83193.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase HTH_45 PF14947.1 AIF83193.1 - 0.2 11.4 1.5 0.33 10.8 0.1 2.0 2 1 0 2 2 2 0 Winged helix-turn-helix DUF2666 PF10869.3 AIF83194.1 - 0.00091 19.2 4.8 0.17 11.9 0.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2666) Prominin PF05478.6 AIF83194.1 - 0.0026 15.3 4.9 0.0035 14.9 3.4 1.2 1 0 0 1 1 1 1 Prominin Translin PF01997.11 AIF83194.1 - 0.0028 17.2 5.0 0.028 14.0 0.3 2.3 2 1 0 2 2 2 1 Translin family IcmL PF11393.3 AIF83194.1 - 0.0057 16.5 1.2 0.71 9.8 0.0 2.8 1 1 2 3 3 3 1 Macrophage killing protein with similarity to conjugation protein PMEI PF04043.10 AIF83194.1 - 0.0087 15.9 2.4 0.017 15.0 1.1 1.8 1 1 1 2 2 2 1 Plant invertase/pectin methylesterase inhibitor HisKA_3 PF07730.8 AIF83194.1 - 0.012 15.8 3.4 14 6.0 0.0 4.0 1 1 1 3 3 3 0 Histidine kinase PhageMin_Tail PF10145.4 AIF83194.1 - 0.019 14.6 5.9 0.3 10.6 4.3 2.1 1 1 1 2 2 2 0 Phage-related minor tail protein CorA PF01544.13 AIF83194.1 - 0.028 13.4 0.7 0.047 12.7 0.2 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein IPPT PF01715.12 AIF83194.1 - 0.033 13.2 0.8 0.04 12.9 0.5 1.2 1 0 0 1 1 1 0 IPP transferase Hpt PF01627.18 AIF83194.1 - 0.052 13.5 0.1 1.7 8.6 0.0 2.8 2 1 0 3 3 3 0 Hpt domain F_actin_bind PF08919.5 AIF83194.1 - 0.053 13.2 4.4 4.7 6.9 0.3 3.2 1 1 0 3 3 3 0 F-actin binding PTPA PF03095.10 AIF83194.1 - 0.059 12.5 4.5 0.27 10.3 0.1 2.0 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein WXG100 PF06013.7 AIF83194.1 - 0.069 13.1 4.7 1.2 9.2 1.6 3.1 2 1 1 3 3 2 0 Proteins of 100 residues with WXG AbiH PF14253.1 AIF83194.1 - 0.092 12.3 1.0 0.17 11.4 0.6 1.4 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH EIIBC-GUT_N PF03612.9 AIF83194.1 - 0.1 12.1 1.7 0.15 11.6 1.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ISG65-75 PF11727.3 AIF83194.1 - 0.12 11.4 6.6 0.11 11.5 3.2 1.7 1 1 1 2 2 2 0 Invariant surface glycoprotein COMP PF11598.3 AIF83194.1 - 0.15 12.1 1.6 1.3 9.1 0.0 2.8 3 1 0 3 3 2 0 Cartilage oligomeric matrix protein Syntaxin-6_N PF09177.6 AIF83194.1 - 0.18 12.2 6.8 11 6.5 4.4 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TBPIP PF07106.8 AIF83194.1 - 0.19 11.2 11.5 0.061 12.8 2.3 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2203 PF09969.4 AIF83194.1 - 0.22 11.7 6.6 0.46 10.7 1.2 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HisKA PF00512.20 AIF83194.1 - 0.24 11.4 2.5 1.9 8.5 0.1 3.0 1 1 2 3 3 3 0 His Kinase A (phospho-acceptor) domain TMP_2 PF06791.8 AIF83194.1 - 0.25 10.9 6.4 0.46 10.0 3.0 2.2 1 1 2 3 3 3 0 Prophage tail length tape measure protein Erp_C PF06780.6 AIF83194.1 - 0.33 10.7 4.9 0.69 9.7 0.1 2.6 1 1 1 2 2 2 0 Erp protein C-terminus hDGE_amylase PF14701.1 AIF83194.1 - 0.41 9.4 3.1 0.45 9.3 2.1 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme FlgN PF05130.7 AIF83194.1 - 0.43 10.8 3.7 2.3 8.4 2.6 2.2 1 1 0 1 1 1 0 FlgN protein Sec8_exocyst PF04048.9 AIF83194.1 - 0.55 9.8 6.2 2.2 7.9 1.5 2.6 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Nairo_nucleo PF02477.10 AIF83194.1 - 0.67 8.5 4.4 0.49 9.0 0.7 2.0 1 1 0 2 2 2 0 Nucleocapsid N protein DASH_Duo1 PF08651.5 AIF83194.1 - 0.71 9.4 7.8 0.88 9.1 0.7 3.1 2 1 0 2 2 2 0 DASH complex subunit Duo1 DUF4661 PF15576.1 AIF83194.1 - 0.94 9.0 3.5 1.2 8.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Muted PF14942.1 AIF83194.1 - 0.98 9.2 6.6 0.96 9.3 3.6 1.7 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein CDC37_N PF03234.9 AIF83194.1 - 1.1 9.5 8.7 0.74 10.1 4.3 1.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding ORF6C PF10552.4 AIF83194.1 - 1.7 8.4 10.4 0.45 10.2 1.6 2.7 1 1 2 3 3 3 0 ORF6C domain eIF3_N PF09440.5 AIF83194.1 - 1.7 8.7 7.0 1.2 9.3 0.4 2.6 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF883 PF05957.8 AIF83194.1 - 3.7 8.0 6.5 12 6.3 0.3 2.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) NEP PF10167.4 AIF83194.1 - 4.2 7.0 7.6 5.7 6.6 0.3 2.8 1 1 1 2 2 2 0 Uncharacterised conserved protein Allexi_40kDa PF05549.6 AIF83194.1 - 6.3 6.0 6.7 4.2 6.5 1.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein COG2 PF06148.6 AIF83194.1 - 8.3 6.2 9.6 3.1 7.6 0.4 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ferritin PF00210.19 AIF83195.1 - 6.1e-25 87.6 0.3 7.7e-25 87.3 0.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain Spermine_synth PF01564.12 AIF83196.1 - 1.2e-08 34.2 0.0 2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 AIF83196.1 - 0.0015 18.5 0.0 0.0042 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF3974 PF13120.1 AIF83196.1 - 0.091 12.5 1.8 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Afaf PF15339.1 AIF83196.1 - 3.7 7.0 4.2 5.5 6.5 0.4 2.3 2 0 0 2 2 2 0 Acrosome formation-associated factor PLDc_2 PF13091.1 AIF83197.1 - 0.013 15.2 1.0 0.6 9.8 0.1 2.5 2 0 0 2 2 2 0 PLD-like domain DUF4242 PF14026.1 AIF83198.1 - 4e-12 46.0 0.0 6.8e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4242) MsyB PF13984.1 AIF83198.1 - 0.079 13.0 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 MsyB protein DUF1831 PF08866.5 AIF83198.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative amino acid metabolism zf-C2H2 PF00096.21 AIF83199.1 - 0.00021 21.4 0.8 0.00064 19.9 0.5 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AIF83199.1 - 0.0032 17.2 1.2 0.0071 16.2 0.8 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AIF83199.1 - 0.0055 16.9 0.3 0.013 15.7 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger DUF2795 PF11387.3 AIF83199.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) zf-C2H2_jaz PF12171.3 AIF83199.1 - 0.022 14.8 1.6 0.044 13.9 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.1 AIF83199.1 - 0.064 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2HC_2 PF13913.1 AIF83199.1 - 0.12 12.0 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Pyridox_oxidase PF01243.15 AIF83201.1 - 8.9e-15 54.4 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF83201.1 - 3.7e-07 30.0 0.0 4.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF658 PF04936.7 AIF83201.1 - 0.013 15.3 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) DUF3596 PF12167.3 AIF83201.1 - 0.065 12.7 0.2 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) Rieske PF00355.21 AIF83202.1 - 9.5e-14 50.7 0.0 1.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AIF83202.1 - 3.2e-06 26.8 0.0 3.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Antitoxin-MazE PF04014.13 AIF83202.1 - 0.039 13.6 0.2 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Acetyltransf_1 PF00583.19 AIF83203.1 - 2.3e-11 43.5 0.0 3.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIF83203.1 - 7e-08 32.5 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIF83203.1 - 4.2e-06 26.8 0.0 8.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIF83203.1 - 5.7e-06 26.2 0.0 2.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIF83203.1 - 0.00048 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 AIF83203.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AIF83203.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF1801 PF08818.6 AIF83204.1 - 1.1e-13 51.1 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DU1801) 3-dmu-9_3-mt PF06983.8 AIF83205.1 - 1.2e-44 151.3 0.3 1.8e-44 150.7 0.2 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase AHSA1 PF08327.6 AIF83206.1 - 5.5e-24 84.6 0.8 6.6e-24 84.3 0.6 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 AIF83206.1 - 1.8e-05 24.9 1.1 2.9e-05 24.2 0.8 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF83206.1 - 0.11 12.4 0.2 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ABM PF03992.11 AIF83208.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Colicin_V PF02674.11 AIF83208.1 - 0.11 12.3 1.5 0.18 11.6 1.0 1.3 1 0 0 1 1 1 0 Colicin V production protein PLDc_2 PF13091.1 AIF83209.1 - 1.9e-10 40.5 1.2 3.3e-10 39.7 0.9 1.4 1 0 0 1 1 1 1 PLD-like domain Kv2channel PF03521.9 AIF83209.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel DUF4042 PF13251.1 AIF83210.1 - 0.099 12.1 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) MRL1 PF13003.2 AIF83210.1 - 0.11 12.2 0.9 5.6 6.7 0.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L1 DDE_Tnp_1 PF01609.16 AIF83212.1 - 1.4e-17 63.9 0.6 3.3e-17 62.7 0.4 1.6 1 1 0 1 1 1 1 Transposase DDE domain EF_assoc_1 PF08355.7 AIF83213.1 - 0.24 10.7 1.4 1.3 8.3 0.0 2.4 2 1 1 3 3 3 0 EF hand associated Plasmid_stabil PF05016.9 AIF83214.1 - 1.1e-07 32.1 0.5 2.2e-07 31.1 0.1 1.6 1 1 1 2 2 2 1 Plasmid stabilisation system protein Gp49 PF05973.9 AIF83214.1 - 0.0008 19.3 0.1 0.0016 18.4 0.0 1.5 1 1 1 2 2 2 1 Phage derived protein Gp49-like (DUF891) Plasmid_Txe PF06769.8 AIF83214.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Plasmid encoded toxin Txe FlbD PF06289.6 AIF83214.1 - 0.16 11.3 0.5 5.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein (FlbD) BCL_N PF04714.8 AIF83214.1 - 0.18 11.4 1.1 0.81 9.2 0.1 2.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Methylase_S PF01420.14 AIF83215.1 - 1.5e-08 34.7 0.2 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain N6_Mtase PF02384.11 AIF83216.1 - 5.7e-31 107.7 0.0 3.1e-30 105.3 0.0 2.1 2 1 0 2 2 2 1 N-6 DNA Methylase HSDR_N_2 PF13588.1 AIF83216.1 - 1.4e-29 102.0 0.0 3.3e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Methyltransf_26 PF13659.1 AIF83216.1 - 1.7e-11 44.1 0.0 2.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AIF83216.1 - 5.1e-09 35.9 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 AIF83216.1 - 0.00022 20.6 0.0 0.023 14.0 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase small domain Eco57I PF07669.6 AIF83216.1 - 0.00042 20.6 0.0 0.0055 17.0 0.0 2.8 2 1 0 2 2 2 1 Eco57I restriction-modification methylase Methyltransf_31 PF13847.1 AIF83216.1 - 0.018 14.6 0.0 0.24 10.9 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain HSDR_N PF04313.9 AIF83216.1 - 0.038 13.7 0.0 0.4 10.3 0.0 2.4 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Imm10 PF15562.1 AIF83217.1 - 0.15 11.8 0.2 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 10 Thioredoxin_4 PF13462.1 AIF83220.1 - 7.1e-31 107.4 0.0 8.7e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AIF83220.1 - 8e-19 67.9 1.0 1.4e-16 60.6 0.7 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 AIF83220.1 - 0.00058 19.4 0.0 0.002 17.7 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AIF83220.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 AIF83220.1 - 0.013 15.2 0.0 2.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_8 PF13905.1 AIF83220.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like DUF953 PF06110.6 AIF83220.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) zf-Mss51 PF13824.1 AIF83220.1 - 0.22 11.4 1.3 14 5.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 AhpC-TSA PF00578.16 AIF83221.1 - 5.9e-36 122.8 0.0 7.4e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIF83221.1 - 3.2e-19 68.9 0.0 4.1e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin adh_short_C2 PF13561.1 AIF83222.1 - 2.1e-32 112.8 0.0 2.7e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AIF83222.1 - 9.5e-27 93.9 0.0 1.2e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIF83222.1 - 8.2e-11 41.8 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Adenine_deam_C PF13382.1 AIF83222.1 - 0.013 14.6 0.3 0.039 13.1 0.2 1.7 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain FixH PF05751.6 AIF83222.1 - 0.029 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 FixH 3HCDH_N PF02737.13 AIF83222.1 - 0.066 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_1 PF00232.13 AIF83222.1 - 0.16 10.1 0.1 0.22 9.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Glyoxalase PF00903.20 AIF83223.1 - 2.5e-28 98.6 0.1 7.8e-14 51.7 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AIF83223.1 - 1.2e-10 41.9 0.0 5.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain DHFR_2 PF06442.6 AIF83223.1 - 0.0024 17.4 0.0 0.59 9.8 0.0 2.4 1 1 1 2 2 2 2 R67 dihydrofolate reductase Abhydrolase_5 PF12695.2 AIF83224.1 - 2.9e-12 46.5 0.0 3.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AIF83224.1 - 5.3e-12 45.6 0.0 9.8e-12 44.7 0.0 1.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AIF83224.1 - 3.4e-08 33.6 0.1 3.3e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIF83224.1 - 5.5e-07 29.0 0.0 0.024 13.8 0.0 2.4 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 AIF83224.1 - 3.9e-06 26.3 0.0 6.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 AIF83224.1 - 0.00055 19.4 0.4 0.0024 17.3 0.1 2.1 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 AIF83224.1 - 0.00062 19.4 0.1 0.0066 16.0 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 AIF83224.1 - 0.0024 17.4 0.0 0.12 11.9 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 AIF83224.1 - 0.12 11.6 0.5 0.9 8.7 0.1 2.2 2 2 0 2 2 2 0 Esterase PHB depolymerase ABM PF03992.11 AIF83225.1 - 0.037 14.0 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DnaB_bind PF10410.4 AIF83225.1 - 0.12 12.3 0.2 15 5.6 0.0 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase TFIIE_alpha PF02002.12 AIF83226.1 - 0.0036 16.7 0.0 0.0044 16.5 0.0 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_9 PF08221.6 AIF83226.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Pyridox_oxidase PF01243.15 AIF83227.1 - 1.3e-11 44.3 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF83227.1 - 0.0017 18.1 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ferritin PF00210.19 AIF83229.1 - 1.3e-21 76.8 0.1 1.6e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain MAAL_C PF07476.6 AIF83229.1 - 0.0011 17.9 0.4 0.043 12.7 0.1 2.1 1 1 1 2 2 2 2 Methylaspartate ammonia-lyase C-terminus Cupin_1 PF00190.17 AIF83230.1 - 6e-28 97.0 0.0 9.7e-14 51.0 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 AIF83230.1 - 1.2e-22 79.1 2.3 4.4e-12 45.3 0.7 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 AIF83230.1 - 5.3e-05 22.5 0.2 0.039 13.3 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 AIF83230.1 - 0.02 14.6 0.6 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain GPI PF06560.6 AIF83230.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) zf-C2H2_4 PF13894.1 AIF83231.1 - 0.00061 19.9 0.1 0.00092 19.3 0.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger DUF4182 PF13790.1 AIF83231.1 - 0.067 13.0 0.6 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4182) zf-Mss51 PF13824.1 AIF83231.1 - 0.081 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Merozoite_SPAM PF07133.6 AIF83232.1 - 3.9 7.3 19.8 4.7 7.0 13.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) APG6 PF04111.7 AIF83233.1 - 0.00048 19.2 0.9 0.00051 19.1 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 Chordopox_A13L PF05961.6 AIF83233.1 - 0.0025 17.6 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Vpu PF00558.14 AIF83233.1 - 0.0034 16.9 4.7 0.0059 16.1 2.0 2.0 1 1 1 2 2 2 1 Vpu protein DUF1049 PF06305.6 AIF83233.1 - 0.019 14.4 0.3 0.076 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Glt_symporter PF03616.9 AIF83233.1 - 0.02 13.4 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Matrilin_ccoil PF10393.4 AIF83233.1 - 0.025 13.9 0.9 0.025 13.9 0.6 2.5 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Alpha-2-MRAP_C PF06401.6 AIF83233.1 - 0.036 13.9 5.4 0.044 13.6 3.7 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Suppressor_APC PF11414.3 AIF83233.1 - 0.036 13.8 4.0 0.053 13.3 2.8 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein FTR1 PF03239.9 AIF83233.1 - 0.048 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family Gly-zipper_Omp PF13488.1 AIF83233.1 - 0.048 13.3 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycine zipper DUF3422 PF11902.3 AIF83233.1 - 0.049 12.5 1.3 0.064 12.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) PTS_EIIC PF02378.13 AIF83233.1 - 0.055 12.2 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC LOH1CR12 PF10158.4 AIF83233.1 - 0.074 12.8 2.1 0.11 12.3 1.4 1.2 1 0 0 1 1 1 0 Tumour suppressor protein DUF2400 PF09674.5 AIF83233.1 - 0.083 12.5 0.6 0.1 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) LXG PF04740.7 AIF83233.1 - 0.09 12.5 8.9 0.24 11.1 1.6 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Cid2 PF09774.4 AIF83233.1 - 0.13 12.3 4.9 0.2 11.7 3.4 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF4381 PF14316.1 AIF83233.1 - 0.14 12.2 0.3 0.27 11.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Ribosomal_S15 PF00312.17 AIF83233.1 - 0.2 11.4 3.7 0.28 10.9 2.6 1.3 1 0 0 1 1 1 0 Ribosomal protein S15 Vac_Fusion PF02346.11 AIF83233.1 - 0.34 10.3 9.2 5.8 6.4 4.2 3.0 1 1 1 2 2 2 0 Chordopoxvirus fusion protein FliT PF05400.8 AIF83233.1 - 0.39 11.1 8.5 0.63 10.4 5.9 1.3 1 0 0 1 1 1 0 Flagellar protein FliT DivIC PF04977.10 AIF83233.1 - 3.2 7.2 6.8 3.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Septum formation initiator XhlA PF10779.4 AIF83233.1 - 3.6 7.5 17.2 1.4 8.9 0.2 3.0 2 1 1 3 3 3 0 Haemolysin XhlA DUF3552 PF12072.3 AIF83233.1 - 9.6 5.3 15.0 2.4 7.3 6.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) P-II PF00543.17 AIF83234.1 - 3.1e-10 40.4 0.2 3.6e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DHHA1 PF02272.14 AIF83234.1 - 0.039 13.6 0.0 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 DHHA1 domain ADH_N PF08240.7 AIF83235.1 - 5.2e-32 109.8 1.5 8.5e-32 109.1 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIF83235.1 - 4e-19 68.4 0.2 6.3e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIF83235.1 - 0.00017 22.4 0.1 0.0007 20.4 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AIF83235.1 - 0.075 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.7 AIF83236.1 - 1.1e-33 115.2 0.1 1.7e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIF83236.1 - 1.1e-31 109.0 0.1 2.4e-31 107.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIF83236.1 - 6.5e-13 49.6 0.1 1.6e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AIF83236.1 - 0.00073 19.1 0.1 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 AIF83236.1 - 0.00086 19.8 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83236.1 - 0.0054 17.1 0.0 0.0093 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.13 AIF83236.1 - 0.027 14.1 0.8 0.042 13.5 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 AIF83236.1 - 0.029 14.3 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 AIF83236.1 - 0.03 14.2 0.9 0.056 13.3 0.6 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Met_10 PF02475.11 AIF83236.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_26 PF13659.1 AIF83236.1 - 0.095 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 AIF83236.1 - 0.097 11.7 0.9 0.14 11.2 0.6 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AIF83236.1 - 0.13 11.5 0.2 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 AIF83237.1 - 1.9e-45 155.1 46.7 5.1e-34 117.5 15.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NPCC PF08058.6 AIF83237.1 - 0.095 12.5 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore complex component MRJP PF03022.11 AIF83238.1 - 4.3e-36 124.5 0.0 6.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 AIF83238.1 - 0.00042 19.7 0.1 0.0036 16.7 0.0 2.4 2 2 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 AIF83238.1 - 0.0048 16.7 1.5 2.1 8.4 0.0 4.0 5 0 0 5 5 5 2 NHL repeat Aldedh PF00171.17 AIF83239.1 - 2.2e-145 484.5 0.5 2.6e-145 484.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MotB_plug PF13677.1 AIF83240.1 - 0.21 10.9 1.0 0.44 9.8 0.7 1.6 1 1 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DNA_binding_1 PF01035.15 AIF83242.1 - 0.013 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain YebO PF13974.1 AIF83242.1 - 0.11 12.2 0.4 0.21 11.3 0.3 1.5 1 1 0 1 1 1 0 YebO-like protein HTH_IclR PF09339.5 AIF83243.1 - 0.00013 21.4 1.2 0.001 18.5 0.3 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_DeoR PF08220.7 AIF83243.1 - 0.0011 18.4 0.8 0.0024 17.3 0.1 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.2 AIF83243.1 - 0.0024 17.6 0.1 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.14 AIF83243.1 - 0.0041 17.0 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain zf-C2H2_4 PF13894.1 AIF83243.1 - 0.012 15.8 1.1 0.031 14.5 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger MarR_2 PF12802.2 AIF83243.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.1 AIF83243.1 - 0.021 15.1 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 AIF83243.1 - 0.024 14.3 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AIF83243.1 - 0.034 13.7 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 HTH domain Dimerisation PF08100.6 AIF83243.1 - 0.056 13.2 0.1 0.72 9.7 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain Rrf2 PF02082.15 AIF83243.1 - 0.075 13.1 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HrcA_DNA-bdg PF03444.10 AIF83243.1 - 0.089 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding zf-C2H2 PF00096.21 AIF83243.1 - 0.096 13.0 1.1 0.31 11.4 0.7 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type HTH_5 PF01022.15 AIF83243.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family CR6_interact PF10147.4 AIF83243.1 - 0.15 11.3 3.9 0.24 10.7 2.7 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 ADH_N PF08240.7 AIF83244.1 - 0.067 12.9 0.4 9.5 6.0 0.0 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF3486 PF11985.3 AIF83246.1 - 0.097 12.7 0.1 0.097 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) TRP_2 PF08344.6 AIF83246.1 - 0.11 12.4 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Transient receptor ion channel II DUF4367 PF14285.1 AIF83249.1 - 2.2e-06 27.0 3.2 0.022 14.1 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4367) NVEALA PF14055.1 AIF83249.1 - 0.23 11.1 1.5 4.3 7.1 1.2 2.2 2 0 0 2 2 2 0 NVEALA protein UPF0547 PF10571.4 AIF83251.1 - 0.001 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-C2HC_2 PF13913.1 AIF83251.1 - 0.068 12.8 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Phage_integrase PF00589.17 AIF83252.1 - 1.3e-11 44.4 0.1 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.1 AIF83252.1 - 0.0015 18.8 0.0 0.0055 17.0 0.0 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 AIF83252.1 - 0.02 15.0 0.0 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF2665 PF11654.3 AIF83253.1 - 0.021 14.3 0.1 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DUF1624 PF07786.7 AIF83253.1 - 0.046 13.0 5.3 0.052 12.8 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) DUF3353 PF11833.3 AIF83253.1 - 0.084 12.3 2.2 0.08 12.3 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) PalH PF08733.5 AIF83253.1 - 0.12 11.1 1.5 0.14 11.0 1.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Myco_arth_vir_N PF09610.5 AIF83253.1 - 0.67 9.9 4.5 0.8 9.7 1.8 2.2 2 1 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) NfeD PF01957.13 AIF83254.1 - 0.06 13.4 0.7 0.062 13.4 0.5 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4149 PF13664.1 AIF83254.1 - 0.078 13.0 1.7 0.31 11.1 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) NrfD PF03916.9 AIF83254.1 - 0.097 12.0 1.6 0.14 11.4 1.1 1.3 1 1 0 1 1 1 0 Polysulphide reductase, NrfD Tetraspannin PF00335.15 AIF83254.1 - 0.3 10.3 1.7 0.37 10.0 1.2 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF3671 PF12420.3 AIF83254.1 - 0.43 10.5 2.5 0.51 10.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF1443 PF07280.6 AIF83254.1 - 8.3 6.0 7.7 0.63 9.6 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1443) ParBc PF02195.13 AIF83255.1 - 1.2e-17 63.8 0.1 4.7e-17 61.8 0.0 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain DZR PF12773.2 AIF83256.1 - 0.0021 17.8 1.0 0.0046 16.7 0.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF83256.1 - 0.0041 16.2 1.1 0.0081 15.3 0.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain UPF0547 PF10571.4 AIF83256.1 - 0.0068 16.0 1.2 0.014 15.1 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Phage_int_SAM_4 PF13495.1 AIF83256.1 - 0.016 15.5 0.6 0.06 13.6 0.4 2.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 AIF83256.1 - 0.034 14.2 0.5 0.094 12.8 0.3 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF2387 PF09526.5 AIF83256.1 - 1.6 8.6 5.2 6.8 6.6 3.6 2.0 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Radical_SAM PF04055.16 AIF83257.1 - 8.6e-12 45.5 0.3 4.2e-11 43.3 0.2 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 AIF83257.1 - 2.9e-08 33.7 0.2 7.1e-08 32.4 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AIF83257.1 - 9.8e-08 32.2 0.1 2e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain EndIII_4Fe-2S PF10576.4 AIF83257.1 - 0.067 13.3 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Cyclase PF04199.8 AIF83258.1 - 2.1e-33 115.4 0.2 2.6e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase AsnC_trans_reg PF01037.16 AIF83259.1 - 1.9e-12 46.7 0.2 2.1e-12 46.5 0.1 1.0 1 0 0 1 1 1 1 AsnC family Aminotran_5 PF00266.14 AIF83260.1 - 3.7e-68 229.9 0.0 4.1e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V AAA_24 PF13479.1 AIF83261.1 - 0.0047 16.5 0.0 0.0061 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.6 AIF83261.1 - 0.065 12.1 0.2 0.18 10.6 0.1 1.9 2 1 0 2 2 2 0 Rad51 OST3_OST6 PF04756.8 AIF83262.1 - 0.00049 19.6 0.4 0.00067 19.2 0.3 1.3 1 1 0 1 1 1 1 OST3 / OST6 family DUF4118 PF13493.1 AIF83262.1 - 0.28 11.3 5.4 0.56 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) DUF3995 PF13160.1 AIF83262.1 - 0.54 10.3 7.2 0.25 11.3 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) zf-HYPF PF07503.7 AIF83263.1 - 0.072 12.5 1.6 0.1 12.0 1.1 1.3 1 0 0 1 1 1 0 HypF finger CHCH PF06747.8 AIF83263.1 - 0.23 11.4 1.6 0.4 10.6 1.1 1.5 1 0 0 1 1 1 0 CHCH domain MbeD_MobD PF04899.7 AIF83263.1 - 0.39 10.6 3.0 3.4 7.6 2.1 2.0 1 1 0 1 1 1 0 MbeD/MobD like Cpn60_TCP1 PF00118.19 AIF83264.1 - 2.8e-169 563.8 16.0 3.2e-169 563.6 11.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rhomboid PF01694.17 AIF83265.1 - 6.3e-32 110.6 18.5 1.1e-31 109.8 12.8 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 AIF83265.1 - 0.073 13.4 0.3 0.073 13.4 0.2 2.5 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) zf-C2H2_4 PF13894.1 AIF83266.1 - 7.1e-06 25.9 0.5 9.2e-06 25.6 0.3 1.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF83266.1 - 3.9e-05 23.7 3.1 5e-05 23.3 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-BED PF02892.10 AIF83266.1 - 0.00017 21.2 0.3 0.0002 21.0 0.2 1.2 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_2 PF12756.2 AIF83266.1 - 0.00053 20.0 0.3 0.00058 19.9 0.2 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 AIF83266.1 - 0.0027 17.1 0.1 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.1 AIF83266.1 - 0.0042 17.2 1.4 0.0067 16.5 0.9 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 AIF83266.1 - 0.0046 17.0 3.3 0.0065 16.5 2.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 AIF83266.1 - 0.0074 16.5 1.8 1.7 9.0 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.7 AIF83266.1 - 0.0093 16.0 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding HNH PF01844.18 AIF83266.1 - 0.024 14.4 0.3 0.032 14.1 0.2 1.2 1 0 0 1 1 1 0 HNH endonuclease DUF629 PF04780.7 AIF83266.1 - 0.036 12.5 0.1 0.037 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF4187 PF13821.1 AIF83266.1 - 0.065 12.8 0.4 0.089 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-CHCC PF10276.4 AIF83266.1 - 0.085 12.7 0.7 0.13 12.0 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger domain Rad50_zn_hook PF04423.9 AIF83266.1 - 0.13 11.7 0.6 0.17 11.3 0.4 1.1 1 0 0 1 1 1 0 Rad50 zinc hook motif AsnC_trans_reg PF01037.16 AIF83267.1 - 7.8e-13 47.9 0.2 8.3e-13 47.8 0.1 1.0 1 0 0 1 1 1 1 AsnC family DUF3600 PF12207.3 AIF83267.1 - 0.041 13.4 0.1 0.044 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) GYD PF08734.6 AIF83267.1 - 0.087 12.5 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 GYD domain HTH_20 PF12840.2 AIF83268.1 - 3.4e-06 26.7 0.2 5.5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 AIF83268.1 - 0.00081 19.0 0.1 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 MarR family HTH_45 PF14947.1 AIF83268.1 - 0.019 14.7 0.1 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_27 PF13463.1 AIF83268.1 - 0.052 13.8 0.1 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain Ribosomal_L11_N PF03946.9 AIF83269.1 - 2.3e-21 74.9 1.1 4.7e-21 74.0 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AIF83269.1 - 1.4e-18 66.8 2.4 2.3e-18 66.0 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Peptidase_S8 PF00082.17 AIF83270.1 - 1.2e-28 100.1 0.0 5.4e-28 97.9 0.0 2.2 1 1 0 1 1 1 1 Subtilase family Big_3_4 PF13754.1 AIF83270.1 - 1.4e-17 63.7 16.3 1.5e-05 25.2 0.8 5.4 4 1 0 4 4 4 3 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.8 AIF83270.1 - 0.0022 17.7 0.5 0.35 10.6 0.0 3.1 3 0 0 3 3 3 1 Y_Y_Y domain DUF1034 PF06280.7 AIF83270.1 - 0.027 14.8 2.3 0.064 13.6 0.0 2.7 3 1 1 4 4 4 0 Fn3-like domain (DUF1034) EF-hand_5 PF13202.1 AIF83270.1 - 0.053 12.8 0.1 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF4625 PF15418.1 AIF83270.1 - 0.1 12.7 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) EF-hand_1 PF00036.27 AIF83270.1 - 0.15 11.4 0.2 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 EF hand Thioredoxin PF00085.15 AIF83271.1 - 5.1e-29 100.0 0.0 5.8e-29 99.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AIF83271.1 - 4.3e-09 36.3 0.1 9.8e-07 28.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AIF83271.1 - 2e-08 34.4 0.1 1.6e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 AIF83271.1 - 2e-07 30.6 0.1 4.5e-07 29.5 0.1 1.7 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 AIF83271.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AIF83271.1 - 1.9e-05 24.3 0.3 0.00011 21.8 0.2 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 AIF83271.1 - 0.00021 20.8 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 AIF83271.1 - 0.0028 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain T4_deiodinase PF00837.12 AIF83271.1 - 0.011 14.7 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase GTP_EFTU PF00009.22 AIF83272.1 - 1.6e-30 105.9 0.0 6e-30 104.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AIF83272.1 - 1.3e-21 76.5 1.2 1.3e-21 76.5 0.8 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.1 AIF83272.1 - 8.2e-14 51.0 0.6 8.2e-14 51.0 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 AIF83272.1 - 9.9e-08 32.0 1.9 2.5e-06 27.5 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AIF83272.1 - 3.2e-07 30.2 0.0 7.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AIF83272.1 - 4.8e-06 27.0 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 AIF83272.1 - 0.00027 20.5 0.0 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 AIF83272.1 - 0.00089 18.6 0.1 0.0085 15.5 0.0 2.3 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 AIF83272.1 - 0.0016 18.2 0.1 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family SRPRB PF09439.5 AIF83272.1 - 0.0025 17.0 0.2 0.33 10.1 0.0 3.3 3 1 0 3 3 3 1 Signal recognition particle receptor beta subunit Pribosyltran PF00156.22 AIF83272.1 - 0.033 13.9 0.8 4.5 7.0 0.0 3.6 4 0 0 4 4 4 0 Phosphoribosyl transferase domain PduV-EutP PF10662.4 AIF83272.1 - 0.05 13.1 0.8 0.33 10.4 0.0 2.8 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 AIF83272.1 - 0.098 12.0 0.6 4.1 6.8 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 AIF83272.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NDK PF00334.14 AIF83273.1 - 1.8e-47 160.4 0.0 2e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ribosomal_L24e PF01246.15 AIF83274.1 - 3.7e-19 68.3 0.9 3.9e-19 68.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e DUF581 PF04570.9 AIF83274.1 - 0.0015 17.7 0.7 0.0024 17.1 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF581) DUF2175 PF09943.4 AIF83274.1 - 0.014 15.3 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-FCS PF06467.9 AIF83274.1 - 0.016 14.8 2.1 0.024 14.2 1.5 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF2116 PF09889.4 AIF83274.1 - 0.25 11.1 2.3 0.88 9.4 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) A2L_zn_ribbon PF08792.5 AIF83274.1 - 1.7 8.2 4.3 22 4.6 0.1 2.5 2 1 1 3 3 3 0 A2L zinc ribbon domain Ribosomal_S28e PF01200.13 AIF83275.1 - 8.8e-31 105.4 6.5 9.3e-31 105.3 4.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L7Ae PF01248.21 AIF83276.1 - 9.3e-27 92.3 0.2 1.2e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Phage_CP76 PF06892.6 AIF83276.1 - 0.03 13.6 0.2 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) DUF4320 PF14208.1 AIF83276.1 - 0.051 13.5 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) PELOTA_1 PF15608.1 AIF83276.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain RNase_P_pop3 PF08228.6 AIF83276.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 AF2331-like PF14556.1 AIF83277.1 - 0.11 12.8 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 AF2331-like DUF1469 PF07332.6 AIF83278.1 - 0.0069 16.1 0.0 0.0094 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) Kinocilin PF15033.1 AIF83282.1 - 0.43 10.1 3.7 0.93 9.0 2.6 1.8 1 1 0 1 1 1 0 Kinocilin protein DUF2269 PF10027.4 AIF83284.1 - 0.013 15.2 0.1 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) IpaB_EvcA PF03278.8 AIF83284.1 - 0.024 13.8 0.2 0.039 13.1 0.1 1.3 1 0 0 1 1 1 0 IpaB/EvcA family OAD_gamma PF04277.8 AIF83284.1 - 0.053 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3792 PF12670.2 AIF83284.1 - 0.16 11.8 4.6 0.063 13.1 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) NfeD PF01957.13 AIF83284.1 - 0.67 10.0 4.7 0.22 11.6 1.1 1.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding TMF_TATA_bd PF12325.3 AIF83287.1 - 0.011 15.4 1.7 0.016 14.9 0.7 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ThylakoidFormat PF11264.3 AIF83287.1 - 0.04 13.5 0.3 0.052 13.1 0.2 1.3 1 0 0 1 1 1 0 Thylakoid formation protein Smoothelin PF12510.3 AIF83287.1 - 0.081 12.8 2.9 5.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Preseq_ALAS PF09029.5 AIF83288.1 - 0.099 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence FlbD PF06289.6 AIF83288.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 1 0 1 1 1 0 Flagellar protein (FlbD) DUF2129 PF09902.4 AIF83290.1 - 0.024 14.3 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) TruD PF01142.13 AIF83293.1 - 0.078 11.6 0.4 0.1 11.2 0.3 1.3 1 1 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) DUF1308 PF07000.6 AIF83293.1 - 0.13 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) DUF3505 PF12013.3 AIF83294.1 - 0.014 15.6 0.8 0.11 12.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) Phage_integrase PF00589.17 AIF83294.1 - 0.022 14.4 0.4 0.022 14.4 0.3 2.5 2 1 0 2 2 2 0 Phage integrase family Tenui_NCP PF04876.7 AIF83294.1 - 0.06 12.8 2.0 0.072 12.6 0.1 2.0 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein Seryl_tRNA_N PF02403.17 AIF83294.1 - 0.28 11.2 14.6 0.55 10.2 4.6 3.5 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.13 AIF83294.1 - 4.2 7.4 7.6 1.8 8.5 0.2 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family PGM_PMM_I PF02878.11 AIF83295.1 - 2.6e-39 133.8 0.0 8.9e-39 132.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AIF83295.1 - 3.7e-25 88.2 0.1 9.4e-25 86.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 AIF83295.1 - 4.8e-22 78.1 0.0 8.9e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 AIF83295.1 - 1.4e-10 41.0 0.0 3.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LGFP PF08310.6 AIF83295.1 - 0.1 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 LGFP repeat AhpC-TSA PF00578.16 AIF83296.1 - 4.6e-07 29.5 0.0 5.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Peptidase_M32 PF02074.10 AIF83297.1 - 1.8e-164 548.0 3.3 2.3e-164 547.7 2.3 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase ThylakoidFormat PF11264.3 AIF83297.1 - 0.0032 17.1 0.1 0.069 12.7 0.2 2.2 2 0 0 2 2 2 1 Thylakoid formation protein TrmB PF01978.14 AIF83297.1 - 0.014 15.1 0.0 0.045 13.4 0.0 1.9 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Gmad2 PF10648.4 AIF83298.1 - 0.096 12.8 0.0 0.24 11.6 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination SNO PF01174.14 AIF83299.1 - 7.7e-51 172.3 0.2 8.8e-51 172.2 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 AIF83299.1 - 1.6e-14 53.7 0.0 2.7e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 AIF83299.1 - 3.6e-10 39.6 0.1 1.3e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIF83299.1 - 2.3e-07 30.5 0.0 2.7e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 Peptidase_S51 PF03575.12 AIF83299.1 - 0.0069 16.1 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 AIF83299.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase DJ-1_PfpI PF01965.19 AIF83299.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family SOR_SNZ PF01680.12 AIF83300.1 - 1.3e-92 309.0 5.5 1.9e-92 308.5 3.8 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 AIF83300.1 - 4.3e-08 32.5 6.1 1.3e-06 27.7 0.1 3.0 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 AIF83300.1 - 4.4e-06 26.1 2.3 0.12 11.6 0.0 3.2 2 1 1 3 3 3 3 Histidine biosynthesis protein Dus PF01207.12 AIF83300.1 - 8.8e-06 24.7 0.6 0.043 12.6 0.2 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 AIF83300.1 - 0.00031 19.9 0.0 0.009 15.0 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 AIF83300.1 - 0.0013 18.0 7.3 0.12 11.4 0.1 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase NanE PF04131.9 AIF83300.1 - 0.0086 15.0 3.7 0.19 10.6 0.0 2.9 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF2046 PF09755.4 AIF83300.1 - 0.045 12.6 0.1 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF1774 PF08611.5 AIF83301.1 - 0.072 13.2 0.2 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) Aconitase PF00330.15 AIF83302.1 - 5.4e-154 513.1 0.0 4.8e-153 509.9 0.0 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AIF83302.1 - 7.2e-38 129.6 0.0 1.4e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain POR_N PF01855.14 AIF83304.1 - 6.7e-64 215.5 0.1 9.7e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 AIF83304.1 - 2.9e-36 124.9 0.1 7e-36 123.7 0.1 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 AIF83304.1 - 7.1e-09 35.6 0.0 2.4e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.13 AIF83304.1 - 0.00088 18.8 0.1 0.002 17.6 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AIF83305.1 - 8.1e-31 106.6 0.1 1.4e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.3 AIF83305.1 - 2.4e-09 36.9 1.0 1.1e-05 25.2 0.0 2.9 3 1 0 3 3 3 2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Cas_csx3 PF09620.5 AIF83305.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) ChaB PF06150.7 AIF83306.1 - 2e-19 69.1 2.9 2.6e-19 68.7 2.0 1.2 1 0 0 1 1 1 1 ChaB MscS_TM PF12794.2 AIF83307.1 - 0.0025 16.5 0.1 0.0025 16.5 0.1 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 2TM PF13239.1 AIF83307.1 - 0.026 14.5 2.1 0.035 14.1 1.4 1.3 1 1 0 1 1 1 0 2TM domain NfeD PF01957.13 AIF83307.1 - 0.066 13.3 0.3 0.079 13.0 0.2 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Bac_export_1 PF01311.15 AIF83307.1 - 0.08 12.1 0.0 0.082 12.1 0.0 1.0 1 0 0 1 1 1 0 Bacterial export proteins, family 1 QCR10 PF09796.4 AIF83307.1 - 0.64 9.7 3.2 4.2 7.1 0.5 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AsnC_trans_reg PF01037.16 AIF83308.1 - 4.7e-14 51.8 0.4 5.1e-14 51.7 0.3 1.0 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 AIF83308.1 - 0.026 14.8 0.5 4.6 7.6 0.1 2.1 2 0 0 2 2 2 0 ACT domain ACT_5 PF13710.1 AIF83308.1 - 0.043 13.6 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 ACT domain Rad50_zn_hook PF04423.9 AIF83310.1 - 0.07 12.6 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF4428 PF14471.1 AIF83310.1 - 0.087 12.5 1.6 0.32 10.7 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Copper-bind PF00127.15 AIF83311.1 - 5.2e-05 23.4 0.0 8.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF83311.1 - 0.00058 19.7 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain DBD_Tnp_Hermes PF10683.4 AIF83311.1 - 0.065 12.7 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain AsnC_trans_reg PF01037.16 AIF83312.1 - 1.7e-11 43.6 0.1 1.9e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 AsnC family DUF1296 PF06972.6 AIF83312.1 - 0.011 15.7 0.8 1.5 8.8 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1296) ACT_4 PF13291.1 AIF83312.1 - 0.013 15.7 0.3 0.018 15.3 0.2 1.2 1 0 0 1 1 1 0 ACT domain NapD PF03927.8 AIF83312.1 - 0.015 15.0 0.2 0.018 14.8 0.2 1.2 1 0 0 1 1 1 0 NapD protein NusG PF02357.14 AIF83312.1 - 0.12 12.6 0.1 9.3 6.5 0.0 2.0 1 1 1 2 2 2 0 Transcription termination factor nusG ABC_tran PF00005.22 AIF83314.1 - 7e-22 78.1 0.0 1.3e-21 77.2 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 AIF83314.1 - 9.5e-13 48.7 0.1 1.9e-11 44.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AIF83314.1 - 5.1e-11 42.2 0.4 7.8e-10 38.3 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 AIF83314.1 - 9.5e-06 24.3 0.0 0.023 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AIF83314.1 - 9.5e-06 25.0 0.1 1.9e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 AIF83314.1 - 2.2e-05 24.8 0.2 5.2e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AIF83314.1 - 0.00011 21.4 0.1 0.00039 19.6 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AIF83314.1 - 0.00017 22.3 0.1 0.00038 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIF83314.1 - 0.0002 20.7 0.1 0.011 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIF83314.1 - 0.0009 19.1 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MutS_V PF00488.16 AIF83314.1 - 0.0015 17.9 0.1 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 MutS domain V AAA_16 PF13191.1 AIF83314.1 - 0.0046 16.9 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ANF_receptor PF01094.23 AIF83314.1 - 0.0046 15.7 0.0 0.15 10.7 0.0 2.2 2 0 0 2 2 2 1 Receptor family ligand binding region AAA_18 PF13238.1 AIF83314.1 - 0.0047 17.2 1.7 0.19 12.0 0.1 2.9 2 2 1 3 3 2 1 AAA domain AAA_15 PF13175.1 AIF83314.1 - 0.006 15.6 0.0 0.3 10.0 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 AIF83314.1 - 0.012 15.0 0.3 0.03 13.7 0.0 1.7 2 1 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 AIF83314.1 - 0.016 15.1 0.1 0.36 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 AIF83314.1 - 0.021 15.0 0.2 0.1 12.8 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 AIF83314.1 - 0.022 13.3 0.1 0.037 12.6 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.18 AIF83314.1 - 0.022 14.7 0.6 0.055 13.4 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 AIF83314.1 - 0.023 14.4 0.3 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Cep57_MT_bd PF06657.8 AIF83314.1 - 0.023 14.6 0.1 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 AAA_22 PF13401.1 AIF83314.1 - 0.029 14.5 0.2 0.36 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 AIF83314.1 - 0.042 12.7 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 AIF83314.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Dynamin_N PF00350.18 AIF83314.1 - 0.054 13.3 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 AIF83314.1 - 0.055 13.4 0.0 0.26 11.2 0.0 2.0 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AIF83314.1 - 0.055 13.6 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 AIF83314.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 AIF83314.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.7 2 1 0 2 2 2 0 NACHT domain AIG1 PF04548.11 AIF83314.1 - 0.11 11.5 0.3 0.64 9.0 0.0 2.0 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.12 AIF83314.1 - 0.11 11.9 0.2 0.66 9.4 0.0 2.3 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 AIF83314.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Chlor_dismutase PF06778.7 AIF83315.1 - 1.5e-55 187.9 0.7 1.9e-55 187.6 0.5 1.1 1 0 0 1 1 1 1 Chlorite dismutase DUF1802 PF08819.6 AIF83316.1 - 6.4e-52 175.7 0.1 7.2e-52 175.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) Aldo_ket_red PF00248.16 AIF83317.1 - 2.1e-54 184.2 0.1 2.5e-54 184.0 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_AsnC-type PF13404.1 AIF83318.1 - 1.2e-07 31.1 0.0 0.00077 18.9 0.0 2.7 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 AIF83318.1 - 2.4e-06 27.1 0.0 0.011 15.4 0.0 3.0 2 1 0 2 2 2 2 AsnC family DUF2250 PF10007.4 AIF83318.1 - 0.013 15.3 0.0 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF3505 PF12013.3 AIF83319.1 - 0.025 14.7 0.2 0.035 14.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) DUF3654 PF12376.3 AIF83319.1 - 0.1 12.3 0.7 0.1 12.4 0.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3654) Ribosomal_L44 PF00935.14 AIF83319.1 - 0.19 11.7 1.1 3.7 7.6 0.3 2.0 1 1 0 2 2 2 0 Ribosomal protein L44 HTH_45 PF14947.1 AIF83320.1 - 6.1e-12 45.1 0.0 7.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF83320.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_34 PF13601.1 AIF83320.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.9 AIF83320.1 - 0.015 15.0 0.2 0.02 14.6 0.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PAX PF00292.13 AIF83320.1 - 0.028 14.1 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain DUF1495 PF07381.6 AIF83320.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Kdo_hydroxy PF11004.3 AIF83321.1 - 0.038 12.9 0.1 0.051 12.5 0.1 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase CxxCxxCC PF03692.10 AIF83322.1 - 3.2e-09 37.1 0.0 7.2e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF504 PF04457.7 AIF83323.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF504) Aconitase_C PF00694.14 AIF83324.1 - 7e-22 77.9 0.0 2.7e-20 72.8 0.0 2.2 1 1 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 AIF83324.1 - 0.0064 15.9 0.1 0.029 13.7 0.1 1.9 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase PF00330.15 AIF83325.1 - 3.6e-81 273.0 6.1 1.4e-54 185.3 0.9 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) DUF521 PF04412.8 AIF83325.1 - 0.015 13.8 0.0 0.023 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) F420_ligase PF01996.11 AIF83326.1 - 5.3e-56 189.2 0.0 6.3e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase TMF_DNA_bd PF12329.3 AIF83327.1 - 0.0095 15.7 0.3 0.024 14.4 0.2 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF4250 PF14056.1 AIF83327.1 - 0.06 13.0 0.2 0.66 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DUF2854 PF11016.3 AIF83329.1 - 0.059 12.8 0.2 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Zn_ribbon_recom PF13408.1 AIF83330.1 - 0.092 13.0 4.9 0.15 12.3 3.4 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 AIF83330.1 - 0.24 11.2 4.5 0.41 10.4 3.1 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 AIF83330.1 - 0.41 10.4 2.7 1.4 8.7 1.9 1.9 1 1 0 1 1 1 0 BED zinc finger HTH_45 PF14947.1 AIF83332.1 - 4.3e-20 71.2 0.8 5.1e-20 71.0 0.6 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF83332.1 - 0.00026 20.6 0.1 0.00032 20.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) PadR PF03551.9 AIF83332.1 - 0.058 13.1 0.1 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_45 PF14947.1 AIF83335.1 - 5.2e-17 61.4 0.0 6.8e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix Chordopox_A30L PF06015.7 AIF83335.1 - 0.055 13.0 0.6 0.092 12.3 0.4 1.3 1 0 0 1 1 1 0 Chordopoxvirus A30L protein DUF4364 PF14277.1 AIF83335.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) zf-C2H2_jaz PF12171.3 AIF83336.1 - 0.62 10.2 3.2 7.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CAP PF00188.21 AIF83337.1 - 2.1e-17 63.7 0.7 4e-17 62.8 0.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4099 PF13351.1 AIF83338.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4099) DUF1376 PF07120.6 AIF83340.1 - 0.0083 16.2 0.1 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1376) PDR_CDR PF06422.7 AIF83340.1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 CDR ABC transporter HNH PF01844.18 AIF83342.1 - 0.0003 20.6 0.4 0.00042 20.1 0.3 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_3 PF13392.1 AIF83342.1 - 0.00051 19.3 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Baculo_ME53 PF06061.6 AIF83342.1 - 0.0073 15.3 0.4 0.0084 15.1 0.3 1.0 1 0 0 1 1 1 1 Baculoviridae ME53 Terminase_GpA PF05876.7 AIF83342.1 - 0.02 13.2 0.2 0.023 13.0 0.2 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DZR PF12773.2 AIF83342.1 - 0.19 11.6 3.2 0.37 10.6 2.2 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-CCHC_3 PF13917.1 AIF83342.1 - 0.2 11.4 1.6 0.45 10.2 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_4 PF13717.1 AIF83342.1 - 0.73 9.5 2.9 3 7.6 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 AIF83342.1 - 0.74 9.5 4.6 5.5 6.7 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal OpgC_C PF10129.4 AIF83344.1 - 0.003 16.3 0.3 0.0034 16.1 0.2 1.0 1 0 0 1 1 1 1 OpgC protein AsnC_trans_reg PF01037.16 AIF83346.1 - 4.2e-13 48.7 0.1 7.1e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 AIF83346.1 - 9.3e-10 37.7 0.7 1.7e-09 36.8 0.5 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF83346.1 - 6.7e-09 35.1 0.2 1.3e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain B-block_TFIIIC PF04182.7 AIF83346.1 - 0.0022 17.7 0.1 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_20 PF12840.2 AIF83346.1 - 0.0026 17.5 0.1 0.0078 15.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.7 AIF83346.1 - 0.01 15.4 0.4 0.028 14.0 0.3 1.7 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.2 AIF83346.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 MarR family TrmB PF01978.14 AIF83346.1 - 0.024 14.3 0.1 0.051 13.2 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_psq PF05225.11 AIF83346.1 - 0.028 13.9 0.3 0.056 12.9 0.2 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain MarR PF01047.17 AIF83346.1 - 0.031 13.9 0.2 0.074 12.7 0.1 1.6 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.1 AIF83346.1 - 0.034 14.1 0.9 0.055 13.5 0.1 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain Rrf2 PF02082.15 AIF83346.1 - 0.054 13.6 0.1 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Sulfolobus_pRN PF05584.6 AIF83346.1 - 0.074 13.0 0.6 0.41 10.6 0.1 2.1 2 1 0 2 2 2 0 Sulfolobus plasmid regulatory protein Ribosomal_S25 PF03297.10 AIF83346.1 - 0.086 12.8 1.4 0.11 12.4 0.3 1.6 2 0 0 2 2 2 0 S25 ribosomal protein HxlR PF01638.12 AIF83347.1 - 3.5e-06 26.5 0.1 4.5e-06 26.1 0.1 1.3 1 1 0 1 1 1 1 HxlR-like helix-turn-helix HTH_45 PF14947.1 AIF83347.1 - 0.00021 21.0 0.0 0.0004 20.1 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix Replic_Relax PF13814.1 AIF83347.1 - 0.00035 20.4 0.1 0.0004 20.3 0.1 1.2 1 0 0 1 1 1 1 Replication-relaxation HTH_20 PF12840.2 AIF83347.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.9 AIF83347.1 - 0.017 14.8 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2513 PF10711.4 AIF83347.1 - 0.022 14.8 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_5 PF01022.15 AIF83347.1 - 0.029 14.0 0.0 2.6 7.7 0.0 2.4 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_34 PF13601.1 AIF83347.1 - 0.079 12.9 0.1 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain Thioredoxin PF00085.15 AIF83350.1 - 3.7e-31 106.8 0.0 4.2e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AIF83350.1 - 2.3e-11 43.8 0.1 8.3e-11 42.0 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AIF83350.1 - 5.6e-09 36.0 0.0 4.5e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 AIF83350.1 - 1.7e-07 30.9 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 AIF83350.1 - 1.8e-07 30.7 0.0 2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 AIF83350.1 - 9.2e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AIF83350.1 - 0.0004 19.9 0.1 0.00091 18.7 0.1 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 AIF83350.1 - 0.0008 19.0 0.1 0.021 14.4 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA family HyaE PF07449.6 AIF83350.1 - 0.0024 17.7 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 AIF83350.1 - 0.025 14.3 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 AIF83350.1 - 0.033 14.4 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 AIF83350.1 - 0.034 14.1 0.1 0.17 11.8 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin TrbC_Ftype PF09673.5 AIF83350.1 - 0.07 12.7 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DUF452 PF04301.8 AIF83351.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF452) tRNA-synt_2c PF01411.14 AIF83352.1 - 2.1e-82 277.1 0.0 3.5e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 AIF83352.1 - 1.1e-15 57.2 4.5 2e-15 56.3 1.0 2.7 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AIF83352.1 - 0.024 14.3 4.6 0.074 12.7 3.2 1.8 1 0 0 1 1 1 0 DHHA1 domain YolD PF08863.5 AIF83352.1 - 0.052 13.4 0.2 0.46 10.3 0.1 2.6 2 1 0 2 2 2 0 YolD-like protein Glutaredoxin2_C PF04399.8 AIF83352.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain tRNA-synt_1 PF00133.17 AIF83353.1 - 1e-66 225.2 0.5 3e-65 220.3 0.3 2.7 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AIF83353.1 - 1.7e-25 89.5 4.0 9.9e-12 44.2 0.1 3.7 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AIF83353.1 - 3.7e-22 78.7 0.3 1.1e-21 77.2 0.2 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 AIF83353.1 - 5.5e-13 48.6 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 AIF83353.1 - 5.7e-13 48.6 0.1 3.7e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain BcrAD_BadFG PF01869.15 AIF83353.1 - 0.076 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family NAD_binding_10 PF13460.1 AIF83354.1 - 4.8e-22 78.8 0.1 7.9e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AIF83354.1 - 7.4e-20 71.2 0.1 9.7e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 AIF83354.1 - 2.3e-05 24.3 0.2 6.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 AIF83354.1 - 0.00077 19.8 1.1 0.0031 17.8 0.0 2.5 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 AIF83354.1 - 0.0015 18.4 0.4 0.0042 17.0 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.10 AIF83354.1 - 0.0018 18.1 0.1 0.005 16.6 0.0 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 AIF83354.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 AIF83354.1 - 0.032 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.1 AIF83354.1 - 0.049 13.8 0.1 0.2 11.8 0.1 2.2 1 1 0 1 1 1 0 CoA binding domain KR PF08659.5 AIF83354.1 - 0.07 12.7 0.3 0.22 11.1 0.2 1.9 1 1 0 1 1 1 0 KR domain Lipase_GDSL_2 PF13472.1 AIF83354.1 - 0.096 12.8 0.2 0.49 10.5 0.1 2.2 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family HTH_24 PF13412.1 AIF83355.1 - 6.8e-23 79.7 0.6 1.2e-10 40.5 0.1 2.6 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF83355.1 - 5.1e-21 73.9 0.1 6.6e-10 38.3 0.0 2.5 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain MarR PF01047.17 AIF83355.1 - 5.8e-06 25.9 0.2 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 1 MarR family TrmB PF01978.14 AIF83355.1 - 6.7e-06 25.7 0.1 0.0058 16.3 0.0 2.7 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AIF83355.1 - 1.9e-05 24.2 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_11 PF08279.7 AIF83355.1 - 0.00019 20.9 0.0 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_5 PF01022.15 AIF83355.1 - 0.00062 19.3 0.1 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AIF83355.1 - 0.00079 19.1 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Mga PF08280.6 AIF83355.1 - 0.0011 18.6 0.0 0.0035 17.0 0.0 1.8 2 0 0 2 2 1 1 M protein trans-acting positive regulator (MGA) HTH domain TFIIE_alpha PF02002.12 AIF83355.1 - 0.0031 17.0 0.3 0.012 15.1 0.1 2.1 3 0 0 3 3 3 1 TFIIE alpha subunit HTH_9 PF08221.6 AIF83355.1 - 0.0057 16.5 0.9 0.43 10.4 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 AIF83355.1 - 0.0072 16.3 0.3 0.15 12.1 0.0 2.7 3 0 0 3 3 3 1 Transposase HTH_IclR PF09339.5 AIF83355.1 - 0.0083 15.6 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.7 AIF83355.1 - 0.014 14.7 0.6 0.53 9.7 0.1 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 AIF83355.1 - 0.021 14.4 0.1 0.59 9.8 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 AIF83355.1 - 0.052 12.7 0.3 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 AIF83355.1 - 0.068 12.4 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 AIF83355.1 - 0.07 13.1 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Adeno_hexon PF01065.14 AIF83355.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain HTH_10 PF04967.7 AIF83355.1 - 0.13 11.8 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain DUF202 PF02656.10 AIF83356.1 - 0.7 10.1 2.6 0.8 9.9 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Pyr_redox_2 PF07992.9 AIF83357.1 - 0.037 13.8 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.19 AIF83357.1 - 0.073 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyoxalase_2 PF12681.2 AIF83358.1 - 3.8e-09 37.1 0.0 5.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF83358.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1428 PF07237.6 AIF83359.1 - 1.9e-07 30.8 0.0 2.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1428) Chromo_shadow PF01393.14 AIF83359.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Chromo shadow domain Prefoldin PF02996.12 AIF83360.1 - 1.5e-18 66.5 7.1 5.8e-18 64.6 5.0 1.8 1 1 0 1 1 1 1 Prefoldin subunit DUF812 PF05667.6 AIF83360.1 - 0.00038 19.1 4.9 0.00044 18.9 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Prefoldin_2 PF01920.15 AIF83360.1 - 0.0065 16.2 3.9 0.0065 16.2 2.7 2.4 1 1 2 3 3 3 1 Prefoldin subunit YlqD PF11068.3 AIF83360.1 - 0.0091 16.0 8.7 0.065 13.2 2.2 2.2 2 0 0 2 2 2 1 YlqD protein Methyltransf_14 PF08484.6 AIF83360.1 - 0.022 14.2 1.3 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain CALCOCO1 PF07888.6 AIF83360.1 - 0.028 12.7 3.7 0.035 12.4 2.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DASH_Dad2 PF08654.5 AIF83360.1 - 0.043 13.8 5.9 0.39 10.7 0.8 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 Prefoldin_3 PF13758.1 AIF83360.1 - 0.057 13.2 0.8 0.11 12.2 0.4 1.9 1 1 0 1 1 1 0 Prefoldin subunit Mod_r PF07200.8 AIF83360.1 - 0.063 13.1 5.2 0.18 11.6 1.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF972 PF06156.8 AIF83360.1 - 0.15 12.3 6.5 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 AIF83360.1 - 0.18 11.1 11.2 0.11 11.8 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Halogen_Hydrol PF10112.4 AIF83360.1 - 0.19 11.1 5.2 0.31 10.4 0.1 2.1 1 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ax_dynein_light PF10211.4 AIF83360.1 - 0.24 11.1 6.6 0.19 11.5 1.0 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain CENP-F_leu_zip PF10473.4 AIF83360.1 - 0.25 11.2 6.8 0.8 9.5 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med21 PF11221.3 AIF83360.1 - 0.28 11.1 6.0 0.26 11.2 1.3 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex EMP24_GP25L PF01105.19 AIF83360.1 - 0.37 10.4 3.8 1.1 8.9 0.2 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF948 PF06103.6 AIF83360.1 - 0.43 10.4 3.2 1.3 8.9 0.2 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Zip PF02535.17 AIF83360.1 - 0.77 8.7 5.0 0.98 8.3 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1178 PF06676.6 AIF83360.1 - 0.95 9.6 6.4 0.22 11.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) CPSF73-100_C PF11718.3 AIF83360.1 - 1.2 8.3 6.5 0.26 10.6 1.8 1.7 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term ABC_tran_2 PF12848.2 AIF83360.1 - 1.4 8.8 12.1 0.72 9.7 4.9 2.1 2 0 0 2 2 2 0 ABC transporter DUF607 PF04678.8 AIF83360.1 - 1.8 8.4 6.3 15 5.4 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF607 SelP_N PF04592.9 AIF83360.1 - 1.9 7.8 13.1 3.2 7.0 9.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LPP20 PF02169.11 AIF83360.1 - 3.3 7.8 6.6 1.2 9.2 1.9 2.0 2 1 0 2 2 2 0 LPP20 lipoprotein FlxA PF14282.1 AIF83360.1 - 6.8 6.6 12.5 16 5.4 0.2 2.3 2 0 0 2 2 2 0 FlxA-like protein SRP54 PF00448.17 AIF83361.1 - 4.9e-69 231.7 0.4 7e-69 231.1 0.3 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 AIF83361.1 - 4.3e-08 33.1 7.2 4.3e-08 33.1 5.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 AIF83361.1 - 2.9e-05 23.7 0.4 2.9e-05 23.7 0.3 1.8 2 0 0 2 2 1 1 AAA domain cobW PF02492.14 AIF83361.1 - 0.00016 21.1 0.1 0.00033 20.1 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.15 AIF83361.1 - 0.00025 20.7 0.1 0.0007 19.2 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 AIF83361.1 - 0.00025 21.1 0.0 0.00064 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AIF83361.1 - 0.00096 18.8 1.7 0.003 17.2 0.3 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 AIF83361.1 - 0.0016 18.1 0.7 0.0034 17.1 0.5 1.5 1 0 0 1 1 1 1 Part of AAA domain CAF-1_p150 PF11600.3 AIF83361.1 - 0.002 17.5 37.8 0.004 16.5 26.2 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_16 PF13191.1 AIF83361.1 - 0.0051 16.8 0.4 0.012 15.5 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 AIF83361.1 - 0.0094 15.3 0.0 0.0094 15.3 0.0 2.7 2 1 0 2 2 1 1 Thymidylate kinase ArgK PF03308.11 AIF83361.1 - 0.038 12.7 3.1 0.27 9.9 2.1 2.4 1 1 0 1 1 1 0 ArgK protein AAA PF00004.24 AIF83361.1 - 0.052 13.7 0.2 0.16 12.2 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AIF83361.1 - 0.06 13.2 0.0 0.06 13.2 0.0 2.5 2 0 0 2 2 1 0 AAA domain Spore_coat_CotO PF14153.1 AIF83361.1 - 0.1 12.0 21.9 0.18 11.2 15.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CDC27 PF09507.5 AIF83361.1 - 0.46 9.6 33.5 0.82 8.8 23.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MAP7 PF05672.6 AIF83361.1 - 0.69 9.2 48.2 1.4 8.2 33.4 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DDHD PF02862.12 AIF83361.1 - 1.2 8.8 10.1 2.6 7.8 7.0 1.6 1 0 0 1 1 1 0 DDHD domain AIF_C PF14721.1 AIF83361.1 - 3.6 7.8 12.6 3.9 7.7 7.4 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.17 AIF83361.1 - 4.2 6.2 4.7 14 4.6 3.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter OTCace_N PF02729.16 AIF83362.1 - 2.3e-51 173.1 0.0 3.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AIF83362.1 - 1.6e-49 167.8 0.0 2.4e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SNARE_assoc PF09335.6 AIF83363.1 - 1.5e-19 70.3 6.7 1.5e-19 70.3 4.6 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein GRA6 PF05084.8 AIF83363.1 - 0.012 15.1 0.2 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) FixQ PF05545.6 AIF83363.1 - 0.071 12.7 0.6 0.071 12.7 0.4 2.5 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF763 PF05559.6 AIF83364.1 - 9.2e-124 412.5 0.0 1.1e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF763) HHH PF00633.18 AIF83364.1 - 0.13 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Rieske PF00355.21 AIF83365.1 - 3.2e-16 58.6 0.0 3.5e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AIF83365.1 - 3.9e-07 29.7 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF77 PF01910.12 AIF83366.1 - 4.9e-23 80.6 2.0 5.5e-23 80.4 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 CoatB PF10389.4 AIF83366.1 - 0.041 13.7 1.9 0.077 12.8 1.3 1.5 1 0 0 1 1 1 0 Bacteriophage coat protein B DOT1 PF08123.8 AIF83367.1 - 1.5e-09 37.4 0.1 2.6e-08 33.4 0.1 2.2 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 AIF83367.1 - 1e-08 35.7 0.1 1.5e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF83367.1 - 2.5e-08 33.9 0.0 3.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF83367.1 - 5.4e-06 26.8 0.0 8.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF83367.1 - 1.7e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIF83367.1 - 2.8e-05 23.3 0.0 3.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 AIF83367.1 - 6e-05 22.6 0.0 9.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AIF83367.1 - 0.00012 21.1 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 AIF83367.1 - 0.00013 21.1 0.2 0.00018 20.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 AIF83367.1 - 0.00071 20.0 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF83367.1 - 0.0011 18.3 0.2 0.0022 17.3 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 AIF83367.1 - 0.015 14.7 0.1 0.034 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4566 PF15130.1 AIF83370.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) PEPCK_ATP PF01293.15 AIF83371.1 - 1.4e-221 736.0 0.0 1.6e-221 735.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PSD1 PF07587.6 AIF83371.1 - 0.045 13.1 0.1 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) AAA_33 PF13671.1 AIF83371.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain UbiA PF01040.13 AIF83373.1 - 1.4e-37 129.3 17.2 1.7e-37 129.0 11.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family WTF PF03303.8 AIF83373.1 - 0.21 11.0 2.4 0.54 9.6 1.0 2.0 2 0 0 2 2 2 0 WTF protein Regulator_TrmB PF11495.3 AIF83374.1 - 0.00046 19.2 1.1 0.012 14.6 0.7 2.1 1 1 0 1 1 1 1 Archaeal transcriptional regulator TrmB TrmB PF01978.14 AIF83374.1 - 0.00094 18.8 0.1 0.0029 17.2 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PLDc_2 PF13091.1 AIF83374.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain HTH_45 PF14947.1 AIF83374.1 - 0.019 14.7 0.5 0.051 13.3 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix TFIIE_alpha PF02002.12 AIF83374.1 - 0.044 13.2 0.2 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_20 PF12840.2 AIF83374.1 - 0.1 12.4 0.1 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain CxxCxxCC PF03692.10 AIF83376.1 - 2.4e-08 34.3 0.3 8.3e-08 32.6 0.2 1.9 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Dak1 PF02733.12 AIF83377.1 - 0.039 12.5 0.0 0.061 11.8 0.0 1.2 1 0 0 1 1 1 0 Dak1 domain LAGLIDADG_3 PF14528.1 AIF83378.1 - 1.2e-15 57.5 0.3 6.7e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 LAGLIDADG-like domain LAGLIDADG_1 PF00961.14 AIF83378.1 - 1.8e-06 28.4 2.4 1.5e-05 25.4 0.4 2.2 2 0 0 2 2 2 1 LAGLIDADG endonuclease Intein_splicing PF14890.1 AIF83378.1 - 0.00058 18.8 1.2 0.0051 15.7 0.8 2.1 1 1 1 2 2 2 1 Intein splicing domain WhiA_N PF10298.4 AIF83378.1 - 0.0087 15.8 0.1 0.023 14.5 0.1 1.8 1 0 0 1 1 1 1 WhiA N-terminal LAGLIDADG-like domain LAGLIDADG_WhiA PF14527.1 AIF83378.1 - 0.012 15.4 0.3 1.3 8.9 0.0 2.7 2 1 1 3 3 3 0 WhiA LAGLIDADG-like domain Sod_Fe_C PF02777.13 AIF83379.1 - 1.6e-40 137.2 2.0 2.1e-40 136.8 0.9 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AIF83379.1 - 4.4e-29 100.5 1.0 4.4e-29 100.5 0.7 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cna_B PF05738.8 AIF83380.1 - 0.01 15.5 0.4 0.055 13.2 0.0 2.4 2 1 0 2 2 2 0 Cna protein B-type domain PPC PF04151.10 AIF83381.1 - 0.023 15.6 1.6 0.09 13.7 0.5 2.6 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Nitroreductase PF00881.19 AIF83383.1 - 5.1e-36 123.9 0.1 6.8e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 Nitroreductase family HMG_CoA_synt_C PF08540.5 AIF83384.1 - 6.8e-33 114.3 0.2 1.2e-32 113.5 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 AIF83384.1 - 3.4e-29 101.6 0.1 7.6e-29 100.4 0.0 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PALP PF00291.20 AIF83385.1 - 4.8e-82 275.6 3.2 6.4e-82 275.2 2.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.20 AIF83385.1 - 0.00016 21.0 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 AIF83385.1 - 0.033 14.5 0.0 0.078 13.3 0.0 1.6 1 0 0 1 1 1 0 ACT domain DUF3582 PF12122.3 AIF83385.1 - 0.098 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) Thr_dehydrat_C PF00585.13 AIF83385.1 - 0.16 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase DUF2024 PF09630.5 AIF83386.1 - 7.5e-34 115.3 1.0 8.3e-34 115.1 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Cytochrom_NNT PF03264.9 AIF83386.1 - 0.035 13.5 0.3 0.036 13.4 0.2 1.1 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Lactamase_B PF00753.22 AIF83387.1 - 7e-23 81.2 2.2 7e-23 81.2 1.5 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIF83387.1 - 0.0079 15.7 0.2 0.012 15.2 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Response_reg PF00072.19 AIF83388.1 - 4.3e-07 29.9 0.0 1.2e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Response regulator receiver domain HTH_24 PF13412.1 AIF83390.1 - 2.4e-08 33.2 0.4 2.4e-08 33.2 0.3 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.8 AIF83390.1 - 0.00074 18.8 1.2 0.011 15.1 0.1 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_20 PF12840.2 AIF83390.1 - 0.00092 18.9 0.3 0.002 17.9 0.0 1.7 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_11 PF08279.7 AIF83390.1 - 0.0013 18.3 1.1 0.0023 17.5 0.2 1.8 2 0 0 2 2 2 1 HTH domain HTH_23 PF13384.1 AIF83390.1 - 0.002 17.7 0.1 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Fe_dep_repress PF01325.14 AIF83390.1 - 0.0031 17.4 0.2 0.0089 15.9 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_AsnC-type PF13404.1 AIF83390.1 - 0.0031 17.0 0.9 0.0099 15.3 0.6 1.9 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain Put_DNA-bind_N PF06971.8 AIF83390.1 - 0.0038 16.9 0.1 0.011 15.4 0.1 1.8 2 0 0 2 2 2 1 Putative DNA-binding protein N-terminus Rrf2 PF02082.15 AIF83390.1 - 0.0047 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.17 AIF83390.1 - 0.0089 15.7 0.3 0.043 13.5 0.0 2.0 2 0 0 2 2 2 1 MarR family Sigma70_r4_2 PF08281.7 AIF83390.1 - 0.012 15.0 0.1 0.029 13.8 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.2 AIF83390.1 - 0.013 15.1 0.1 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 MarR family GerE PF00196.14 AIF83390.1 - 0.016 14.5 0.1 0.034 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family RuvB_C PF05491.8 AIF83390.1 - 0.016 14.8 0.1 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB C-terminus HTH_IclR PF09339.5 AIF83390.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.14 AIF83390.1 - 0.027 14.1 0.3 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AIF83390.1 - 0.035 13.7 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF3465 PF11948.3 AIF83390.1 - 0.041 13.6 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) HTH_6 PF01418.12 AIF83390.1 - 0.044 13.5 0.3 0.11 12.2 0.0 1.8 2 0 0 2 2 1 0 Helix-turn-helix domain, rpiR family GntR PF00392.16 AIF83390.1 - 0.046 13.1 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family RP-C PF03428.8 AIF83390.1 - 0.049 13.0 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain AsnC_trans_reg PF01037.16 AIF83390.1 - 0.062 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AsnC family Dimerisation PF08100.6 AIF83390.1 - 0.068 13.0 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 1 0 Dimerisation domain HTH_28 PF13518.1 AIF83390.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 AIF83391.1 - 0.011 15.3 0.1 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.1 AIF83393.1 - 5e-09 35.4 0.1 1.1e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF83393.1 - 4.1e-08 32.6 0.2 8.1e-08 31.6 0.1 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AIF83393.1 - 8.9e-05 22.0 1.8 8.9e-05 22.0 0.1 1.8 2 0 0 2 2 1 1 HTH domain HTH_23 PF13384.1 AIF83393.1 - 0.0015 18.1 0.1 0.0036 16.9 0.0 1.7 2 0 0 2 2 1 1 Homeodomain-like domain Put_DNA-bind_N PF06971.8 AIF83393.1 - 0.0046 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus AsnC_trans_reg PF01037.16 AIF83393.1 - 0.0049 16.5 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 AsnC family MarR_2 PF12802.2 AIF83393.1 - 0.022 14.4 0.1 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.1 AIF83393.1 - 0.026 13.6 0.0 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.5 AIF83393.1 - 0.028 14.0 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_psq PF05225.11 AIF83393.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_20 PF12840.2 AIF83393.1 - 0.036 13.8 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF603 PF04645.7 AIF83393.1 - 0.049 13.5 0.0 0.092 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF603 Sigma70_r4_2 PF08281.7 AIF83393.1 - 0.07 12.5 0.3 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 GntR PF00392.16 AIF83393.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_38 PF13936.1 AIF83393.1 - 0.077 12.5 0.2 0.31 10.6 0.0 2.1 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_28 PF13518.1 AIF83393.1 - 0.094 12.7 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Mga PF05043.8 AIF83393.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain GerE PF00196.14 AIF83393.1 - 0.1 11.9 0.1 0.56 9.5 0.0 2.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family TrmB PF01978.14 AIF83393.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB NHL PF01436.16 AIF83395.1 - 1.2e-28 97.6 0.0 0.00013 21.7 0.0 7.6 7 0 0 7 7 7 6 NHL repeat Redoxin PF08534.5 AIF83395.1 - 5.3e-14 51.9 0.0 4.2e-13 49.0 0.0 2.4 3 0 0 3 3 3 1 Redoxin Thioredoxin_8 PF13905.1 AIF83395.1 - 2e-12 47.0 0.1 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AIF83395.1 - 3.7e-12 45.9 0.0 9.6e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family SGL PF08450.7 AIF83395.1 - 4.7e-07 29.4 0.4 0.0044 16.4 0.0 3.7 4 0 0 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region Thioredoxin_2 PF13098.1 AIF83395.1 - 7.7e-07 29.2 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 AIF83395.1 - 1.7e-05 24.3 0.7 0.026 14.2 0.1 2.7 3 0 0 3 3 3 2 Thioredoxin YtfJ_HI0045 PF09695.5 AIF83395.1 - 0.006 15.9 0.1 0.019 14.3 0.1 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) LVIVD PF08309.6 AIF83395.1 - 0.021 13.7 0.3 0.94 8.5 0.0 3.3 4 0 0 4 4 4 0 LVIVD repeat TrbC_Ftype PF09673.5 AIF83395.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Nitroreductase PF00881.19 AIF83396.1 - 1.3e-27 96.6 0.0 1.6e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF432 PF04254.8 AIF83397.1 - 7e-30 103.4 0.1 1e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF432) CorA PF01544.13 AIF83398.1 - 3.9e-60 203.3 0.1 4.5e-60 203.1 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TelA PF05816.6 AIF83398.1 - 0.0088 14.7 0.3 0.017 13.8 0.2 1.3 1 1 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF1351 PF07083.6 AIF83398.1 - 0.011 15.4 0.2 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) HsdM_N PF12161.3 AIF83398.1 - 0.027 14.9 0.5 0.14 12.6 0.3 2.0 1 1 0 1 1 1 0 HsdM N-terminal domain Baculo_LEF-11 PF06385.7 AIF83398.1 - 0.12 12.4 0.2 0.34 11.0 0.0 1.9 1 1 0 1 1 1 0 Baculovirus LEF-11 protein MS_channel PF00924.13 AIF83399.1 - 1.3e-51 174.9 0.4 1.3e-51 174.9 0.2 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel HeH PF12949.2 AIF83399.1 - 0.15 11.6 0.0 0.57 9.7 0.0 1.9 2 0 0 2 2 2 0 HeH/LEM domain MFS_1 PF07690.11 AIF83400.1 - 1.8e-30 105.8 41.4 2.2e-19 69.3 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AIF83400.1 - 1.2e-09 37.0 25.7 5e-09 35.0 17.8 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein IcmF-related PF06761.7 AIF83401.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Guanylate_cyc PF00211.15 AIF83402.1 - 1.9e-19 69.7 0.1 2.6e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ribosomal_S9 PF00380.14 AIF83403.1 - 2.3e-32 111.8 0.4 2.6e-32 111.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.13 AIF83404.1 - 2.5e-25 89.0 0.2 3e-25 88.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L18e PF00828.14 AIF83405.1 - 1.5e-13 51.2 0.6 1.9e-13 50.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_A_bac PF01000.21 AIF83406.1 - 2.2e-27 95.4 0.0 4.9e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AIF83406.1 - 3e-13 48.6 0.0 3.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 AIF83406.1 - 0.0031 16.9 0.1 0.006 16.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Thioredoxin_3 PF13192.1 AIF83406.1 - 0.26 11.1 2.5 4.3 7.2 0.1 2.8 2 1 0 2 2 2 0 Thioredoxin domain SBDS PF01172.13 AIF83407.1 - 3.5e-24 84.3 0.0 5.6e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 AIF83407.1 - 8.4e-21 73.9 0.1 3.7e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 SBDS protein C-terminal domain XkdN PF08890.6 AIF83407.1 - 0.036 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage XkdN-like protein HD_assoc PF13286.1 AIF83407.1 - 0.21 11.8 1.7 1.9 8.8 0.2 2.8 1 1 2 3 3 3 0 Phosphohydrolase-associated domain DNA_binding_1 PF01035.15 AIF83408.1 - 2e-31 107.5 2.9 9.2e-31 105.4 0.5 2.6 2 1 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.11 AIF83408.1 - 1.6e-30 104.4 4.2 3.6e-30 103.3 2.9 1.7 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.2 AIF83408.1 - 1.5e-19 69.8 0.5 1.2e-18 66.9 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.18 AIF83408.1 - 1.7e-14 53.1 0.1 1.7e-07 30.8 0.0 3.0 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Methyltransf_1N PF02870.10 AIF83408.1 - 0.003 18.1 0.0 0.0074 16.8 0.0 1.7 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain E1-N PF14463.1 AIF83408.1 - 0.065 12.8 0.2 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 E1 N-terminal domain TetR_N PF00440.18 AIF83408.1 - 0.15 11.7 0.3 0.6 9.7 0.0 2.2 2 1 1 3 3 3 0 Bacterial regulatory proteins, tetR family KH_1 PF00013.24 AIF83410.1 - 4.3e-12 45.5 2.1 9e-12 44.4 1.4 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AIF83410.1 - 7.9e-05 22.2 1.5 0.00022 20.8 1.1 1.8 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 AIF83410.1 - 0.00055 19.4 0.9 0.0013 18.2 0.3 1.8 1 1 0 1 1 1 1 KH domain RNase_PH PF01138.16 AIF83411.1 - 4.2e-34 117.7 0.0 5.8e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AIF83411.1 - 4.6e-15 55.2 0.4 1.5e-14 53.6 0.2 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 AIF83412.1 - 4.7e-28 98.1 0.0 7.6e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AIF83412.1 - 6.7e-07 29.1 0.2 2.1e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF3237 PF11578.3 AIF83412.1 - 0.013 14.8 0.0 0.72 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) Ribosomal_L37ae PF01780.14 AIF83413.1 - 1.4e-15 56.9 1.5 1.4e-15 56.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 AIF83413.1 - 3.5e-05 23.5 2.8 5e-05 23.0 2.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF83413.1 - 0.0023 17.0 1.2 0.77 9.0 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIF83413.1 - 0.0088 15.6 0.7 0.012 15.3 0.5 1.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain zf-RanBP PF00641.13 AIF83413.1 - 0.052 12.6 3.9 0.28 10.3 0.4 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.1 AIF83413.1 - 0.072 12.5 2.0 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 AIF83413.1 - 0.081 12.6 0.7 0.12 12.1 0.5 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_4 PF13894.1 AIF83413.1 - 0.1 12.9 0.6 5 7.6 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger VP_N-CPKC PF11475.3 AIF83413.1 - 0.13 11.8 3.0 1.3 8.6 0.5 2.2 2 0 0 2 2 2 0 Virion protein N terminal domain Rubredoxin PF00301.15 AIF83413.1 - 0.14 12.0 3.3 6.5 6.7 0.6 2.2 1 1 1 2 2 2 0 Rubredoxin DUF4379 PF14311.1 AIF83413.1 - 0.2 11.4 2.3 7.8 6.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) DZR PF12773.2 AIF83413.1 - 0.21 11.4 1.6 3 7.7 1.4 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-ISL3 PF14690.1 AIF83413.1 - 0.21 11.6 3.7 1.9 8.5 0.2 2.5 3 0 0 3 3 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_5 PF13719.1 AIF83413.1 - 0.27 10.8 3.0 7.6 6.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIF83413.1 - 0.36 10.5 3.1 8.3 6.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 AIF83413.1 - 0.37 10.3 4.3 6.6 6.3 0.1 2.6 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-NADH-PPase PF09297.6 AIF83413.1 - 0.38 10.2 0.3 0.38 10.2 0.2 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-tcix PF14952.1 AIF83413.1 - 0.44 9.9 6.7 3.6 7.0 1.2 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding UPF0547 PF10571.4 AIF83413.1 - 0.55 9.9 4.5 7.6 6.3 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DNA_ligase_ZBD PF03119.11 AIF83413.1 - 0.55 9.9 4.3 1 9.0 0.5 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-CSL PF05207.8 AIF83413.1 - 2.2 7.8 4.3 21 4.6 3.0 2.1 1 1 0 1 1 1 0 CSL zinc finger Zn-ribbon_8 PF09723.5 AIF83413.1 - 2.5 8.1 6.1 1.6 8.7 0.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Pcc1 PF09341.5 AIF83414.1 - 2e-12 46.9 0.0 2.2e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Prefoldin_2 PF01920.15 AIF83415.1 - 1e-21 76.7 14.7 1.1e-21 76.5 10.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit Cortex-I_coil PF09304.5 AIF83415.1 - 0.001 19.1 8.4 0.024 14.6 0.9 2.2 2 0 0 2 2 2 2 Cortexillin I, coiled coil DUF919 PF06034.6 AIF83415.1 - 0.056 13.0 0.9 0.056 13.0 0.7 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF4657 PF15552.1 AIF83415.1 - 0.18 11.0 3.9 0.25 10.6 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) DHHA1 PF02272.14 AIF83415.1 - 0.19 11.4 3.1 0.15 11.7 0.5 2.0 2 0 0 2 2 2 0 DHHA1 domain ETC_C1_NDUFA5 PF04716.9 AIF83415.1 - 0.26 10.8 3.6 5.7 6.5 2.5 2.5 1 1 0 1 1 1 0 ETC complex I subunit conserved region Mod_r PF07200.8 AIF83415.1 - 0.45 10.4 9.7 0.64 9.9 0.9 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin PF02996.12 AIF83415.1 - 0.53 9.9 10.9 0.64 9.6 1.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 AIF83415.1 - 0.67 9.8 14.5 1.3 8.8 1.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sipho_Gp157 PF05565.6 AIF83415.1 - 0.67 9.5 8.8 1 8.9 6.1 1.3 1 1 0 1 1 1 0 Siphovirus Gp157 DUF972 PF06156.8 AIF83415.1 - 1.3 9.4 9.9 1.8 8.9 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 AIF83415.1 - 1.3 9.2 6.8 1.9 8.7 4.7 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 AIF83415.1 - 3.7 7.2 12.3 1.3 8.7 1.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ribosomal_60s PF00428.14 AIF83415.1 - 3.9 7.9 10.1 1.8 9.0 0.2 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein CDC37_N PF03234.9 AIF83415.1 - 5.7 7.2 12.2 10 6.3 8.4 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4200 PF13863.1 AIF83415.1 - 6.9 6.6 12.7 0.77 9.7 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2203 PF09969.4 AIF83415.1 - 8.5 6.6 8.0 1.1e+02 3.0 5.5 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.6 AIF83415.1 - 8.8 6.0 10.7 4.3e+02 0.6 7.5 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF904 PF06005.7 AIF83415.1 - 8.9 6.6 12.6 2.6 8.3 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TIP120 PF08623.5 AIF83415.1 - 8.9 5.8 8.4 12 5.3 1.0 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) ERCC4 PF02732.10 AIF83416.1 - 1e-21 77.1 0.0 1.5e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 AIF83416.1 - 2.1e-09 37.4 0.2 8.5e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 AIF83416.1 - 1.1e-05 25.2 0.0 3.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.18 AIF83416.1 - 0.0003 20.3 0.1 1 9.1 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.1 AIF83416.1 - 0.0032 17.6 0.0 2.2 8.5 0.0 3.2 2 1 1 3 3 3 2 Helix-hairpin-helix domain IMS_HHH PF11798.3 AIF83416.1 - 0.0061 16.5 0.0 0.07 13.2 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif HHH_3 PF12836.2 AIF83416.1 - 0.019 14.8 0.1 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Transposase_20 PF02371.11 AIF83416.1 - 0.024 14.7 0.0 0.34 11.0 0.0 2.5 1 1 1 2 2 2 0 Transposase IS116/IS110/IS902 family Rhodanese PF00581.15 AIF83417.1 - 4.3e-38 130.1 0.1 6.1e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Redoxin PF08534.5 AIF83417.1 - 0.12 11.9 0.0 2 7.9 0.0 2.3 1 1 0 2 2 2 0 Redoxin PIN PF01850.16 AIF83418.1 - 1.2e-06 28.8 3.5 1.8e-06 28.2 2.4 1.3 1 0 0 1 1 1 1 PIN domain NOB1_Zn_bind PF08772.6 AIF83418.1 - 0.00036 20.2 0.9 0.00064 19.4 0.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 AIF83418.1 - 0.0051 15.9 2.5 0.0082 15.3 1.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain FdhE PF04216.7 AIF83418.1 - 0.0066 16.1 0.6 0.0066 16.1 0.4 1.6 1 1 0 1 1 1 1 Protein involved in formate dehydrogenase formation DZR PF12773.2 AIF83418.1 - 0.0073 16.1 0.6 0.013 15.3 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon DUF35_N PF12172.3 AIF83418.1 - 0.02 14.7 0.2 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) UPF0278 PF08745.6 AIF83418.1 - 0.024 13.9 0.2 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 UPF0278 family zf-C3HC4_3 PF13920.1 AIF83418.1 - 0.026 14.1 0.8 0.043 13.5 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 AIF83418.1 - 0.067 12.8 0.7 0.1 12.2 0.5 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Nudix_N_2 PF14803.1 AIF83418.1 - 0.12 12.0 2.3 5 6.8 0.3 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 AIF83418.1 - 0.17 11.4 3.6 7.6 6.1 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 AIF83418.1 - 0.19 11.5 3.1 6.3 6.6 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 AIF83418.1 - 0.43 10.9 4.4 10 6.6 0.3 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 AIF83418.1 - 0.5 10.3 3.0 6.2 6.8 2.1 2.3 1 1 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 AIF83418.1 - 0.82 9.9 4.8 2.7 8.3 0.3 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-C4_Topoisom PF01396.14 AIF83418.1 - 1.2 8.7 4.9 0.21 11.1 0.6 1.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger NAD_kinase PF01513.16 AIF83419.1 - 7.9e-32 110.1 0.6 1.1e-31 109.6 0.4 1.3 1 1 0 1 1 1 1 ATP-NAD kinase Rhodanese PF00581.15 AIF83420.1 - 2.1e-43 147.2 0.1 2.5e-25 89.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Fer4 PF00037.22 AIF83422.1 - 8.1e-09 34.7 17.9 0.00016 21.1 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AIF83422.1 - 6.1e-07 29.7 7.7 1.4e-06 28.6 5.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIF83422.1 - 6.6e-07 29.4 6.8 1.6e-06 28.2 4.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF83422.1 - 6.9e-05 22.5 8.7 0.00018 21.2 6.1 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AIF83422.1 - 8.3e-05 22.3 7.7 0.00014 21.6 5.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF83422.1 - 0.00015 21.6 6.4 0.00029 20.7 4.2 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AIF83422.1 - 0.00033 21.0 4.0 0.13 12.6 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIF83422.1 - 0.00041 20.0 13.9 0.083 12.7 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 AIF83422.1 - 0.0045 16.8 14.5 0.22 11.4 1.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain MSP1_C PF07462.6 AIF83422.1 - 0.021 13.2 2.0 0.028 12.8 1.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Fer4_3 PF12798.2 AIF83422.1 - 0.026 15.0 16.8 0.48 11.1 2.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2360 PF10152.4 AIF83422.1 - 0.065 13.5 2.1 0.1 12.8 1.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Fer4_4 PF12800.2 AIF83422.1 - 0.087 13.2 11.3 0.53 10.7 1.2 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 AIF83422.1 - 0.4 11.0 8.8 4.5 7.6 0.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 AIF83422.1 - 0.45 11.2 10.1 2.2 9.0 1.7 2.6 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_13 PF13370.1 AIF83422.1 - 0.83 10.0 10.3 1.3 9.5 0.6 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 AIF83422.1 - 2.7 8.6 12.7 1.7 9.2 1.1 2.9 3 0 0 3 3 2 0 4Fe-4S single cluster domain Glyco_tranf_2_3 PF13641.1 AIF83423.1 - 3.9e-37 128.2 0.0 6.4e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AIF83423.1 - 6.5e-23 81.4 1.1 6.5e-23 81.4 0.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 AIF83423.1 - 3.4e-20 72.4 0.0 6.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AIF83423.1 - 2.2e-16 59.6 0.1 4e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF83423.1 - 0.0081 15.2 0.1 0.024 13.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.9 AIF83423.1 - 0.012 13.9 0.4 0.021 13.1 0.0 1.6 2 0 0 2 2 2 0 Cellulose synthase Chordopox_G3 PF06129.7 AIF83423.1 - 0.033 14.3 0.4 0.55 10.4 0.1 2.5 1 1 0 2 2 2 0 Chordopoxvirus G3 protein SMP_2 PF10144.4 AIF83425.1 - 0.16 11.1 0.2 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin DUF4179 PF13786.1 AIF83426.1 - 0.037 14.2 0.0 0.044 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2813 PF11398.3 AIF83427.1 - 0.064 12.3 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Cas_Cas1 PF01867.11 AIF83429.1 - 1.6e-47 161.9 0.0 2.1e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 SAM_adeno_trans PF01887.11 AIF83429.1 - 0.07 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase HEPN PF05168.9 AIF83430.1 - 8.1e-08 32.1 6.3 1.1e-07 31.7 2.4 2.5 2 1 0 2 2 2 1 HEPN domain Pentapeptide PF00805.17 AIF83432.1 - 3.1e-36 122.0 25.9 1.6e-09 36.7 1.5 6.9 3 3 3 7 7 7 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 AIF83432.1 - 1.8e-27 94.9 12.1 1e-09 38.0 4.9 4.5 2 2 2 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 AIF83432.1 - 4e-21 74.6 7.6 1.4e-07 31.2 3.7 6.4 2 2 4 6 6 6 6 Pentapeptide repeats (9 copies) NACHT PF05729.7 AIF83432.1 - 1.9e-07 30.8 0.1 6.5e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 AIF83432.1 - 0.07 13.3 0.1 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol_B_2 PF03175.8 AIF83433.1 - 6.4e-12 44.8 5.8 1.5e-11 43.6 0.4 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral Phage_T4_Ndd PF06591.6 AIF83433.1 - 0.021 14.4 0.0 0.093 12.2 0.0 2.0 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) SspH PF08141.7 AIF83434.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Small acid-soluble spore protein H family HxlR PF01638.12 AIF83436.1 - 0.0085 15.6 2.1 0.065 12.8 0.0 3.1 1 1 3 4 4 4 1 HxlR-like helix-turn-helix FliT PF05400.8 AIF83436.1 - 0.011 16.1 0.6 0.033 14.5 0.1 2.0 2 0 0 2 2 2 0 Flagellar protein FliT HTH_27 PF13463.1 AIF83436.1 - 0.063 13.6 0.0 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain MarR_2 PF12802.2 AIF83436.1 - 0.082 12.5 0.2 0.59 9.8 0.1 2.4 2 0 0 2 2 2 0 MarR family Occludin_ELL PF07303.8 AIF83436.1 - 0.65 10.7 4.8 0.51 11.0 2.0 1.9 2 1 0 2 2 2 0 Occludin homology domain Ribosomal_L29 PF00831.18 AIF83436.1 - 4.7 6.9 7.2 1.5 8.5 0.1 2.8 3 0 0 3 3 3 0 Ribosomal L29 protein HicB PF05534.7 AIF83437.1 - 0.0028 17.1 0.1 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 HicB family RHH_1 PF01402.16 AIF83437.1 - 0.027 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family PAP_fibrillin PF04755.7 AIF83438.1 - 0.09 12.4 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 PAP_fibrillin Folliculin PF11704.3 AIF83438.1 - 0.12 11.9 0.4 0.14 11.7 0.3 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1136 PF06582.7 AIF83438.1 - 0.37 10.5 0.3 0.37 10.5 0.2 1.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) DUF3237 PF11578.3 AIF83439.1 - 1.3e-08 34.2 0.5 4.8e-08 32.4 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DUF3108 PF11306.3 AIF83440.1 - 0.0014 18.3 0.1 0.003 17.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3108) PepSY PF03413.14 AIF83442.1 - 0.00051 20.6 2.0 0.00089 19.8 1.4 1.7 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain LrgB PF04172.11 AIF83442.1 - 0.011 14.9 0.2 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 LrgB-like family CLU PF13236.1 AIF83442.1 - 0.07 12.5 0.1 0.17 11.2 0.1 1.6 1 1 1 2 2 2 0 Clustered mitochondria DUF1034 PF06280.7 AIF83444.1 - 0.061 13.7 0.2 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) zf-FPG_IleRS PF06827.9 AIF83446.1 - 0.019 14.5 2.9 0.031 13.9 2.0 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS YhfH PF14149.1 AIF83446.1 - 0.17 11.6 1.7 0.35 10.6 0.9 1.8 1 1 0 1 1 1 0 YhfH-like protein Ribosomal_60s PF00428.14 AIF83446.1 - 2.5 8.5 7.1 3.2 8.2 4.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-ribbon_3 PF13248.1 AIF83446.1 - 6.2 6.1 8.1 0.98 8.7 2.5 2.0 2 1 0 2 2 2 0 zinc-ribbon domain DUF496 PF04363.7 AIF83447.1 - 1.9 8.3 5.7 6.6 6.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF496) ALAD PF00490.16 AIF83448.1 - 2e-134 447.5 0.0 2.2e-134 447.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF354 PF04007.7 AIF83448.1 - 0.12 11.2 0.0 0.38 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF354) GlutR_N PF05201.10 AIF83449.1 - 4.8e-41 139.8 0.4 9.4e-41 138.9 0.2 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 AIF83449.1 - 4e-25 88.4 0.1 1.3e-24 86.8 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.15 AIF83449.1 - 3.4e-17 62.2 0.5 6.9e-17 61.2 0.3 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain 2-Hacid_dh_C PF02826.14 AIF83449.1 - 0.0019 17.3 0.0 0.0037 16.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AIF83449.1 - 0.049 13.8 0.2 0.15 12.2 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_7 PF13241.1 AIF83450.1 - 2.4e-20 72.7 0.0 5.4e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 AIF83450.1 - 0.00083 19.4 0.7 0.0023 18.0 0.1 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 AIF83450.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain Sirohm_synth_M PF14824.1 AIF83450.1 - 0.018 14.0 0.1 0.041 12.8 0.1 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Pyr_redox PF00070.22 AIF83450.1 - 0.02 15.2 1.0 0.11 12.8 0.1 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CysG_dimeriser PF10414.4 AIF83450.1 - 0.061 12.8 0.1 0.15 11.5 0.1 1.7 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Spt5-NGN PF03439.8 AIF83451.1 - 1.4e-21 76.0 0.0 2.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 AIF83451.1 - 7e-08 31.8 0.1 1.5e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 KOW motif NusG PF02357.14 AIF83451.1 - 0.0035 17.5 0.0 0.0079 16.4 0.0 1.6 1 1 0 1 1 1 1 Transcription termination factor nusG tRNA_deacylase PF04414.7 AIF83452.1 - 8.4e-63 211.3 0.0 9.8e-63 211.1 0.0 1.0 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase DNA_binding_1 PF01035.15 AIF83453.1 - 6.9e-31 105.8 0.0 9.5e-31 105.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ribosomal_L19e PF01280.15 AIF83454.1 - 8.8e-41 139.1 10.2 9.8e-41 138.9 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e HTH_12 PF08461.5 AIF83454.1 - 0.0051 16.5 0.3 0.01 15.5 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Ribosomal_L32e PF01655.13 AIF83455.1 - 2.1e-41 140.3 0.7 2.6e-41 140.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Metallophos PF00149.23 AIF83457.1 - 1.4e-20 73.5 0.3 2e-20 73.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AIF83457.1 - 2.4e-05 24.2 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_2 PF12706.2 AIF83458.1 - 8.5e-29 100.4 0.0 1.2e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AIF83458.1 - 8.8e-09 35.2 0.0 8.4e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 AIF83458.1 - 0.00086 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Pribosyltran_N PF13793.1 AIF83459.1 - 1e-26 92.9 0.1 1.4e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AIF83459.1 - 3.2e-20 72.6 1.1 3.5e-19 69.2 0.8 2.3 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AIF83459.1 - 4e-15 55.6 2.7 7.3e-15 54.7 0.1 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AIF83459.1 - 1.8e-05 24.0 0.1 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF2393 PF09624.5 AIF83460.1 - 3.6e-05 23.3 2.8 0.016 14.7 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2393) DUF3426 PF11906.3 AIF83460.1 - 0.00012 21.7 0.4 0.36 10.4 0.0 2.9 2 1 0 3 3 3 2 Protein of unknown function (DUF3426) DUF309 PF03745.9 AIF83461.1 - 1.6e-17 62.6 0.1 2.9e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF309) Cu-oxidase_3 PF07732.10 AIF83462.1 - 5.4e-28 97.0 5.0 1.3e-23 82.9 0.3 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AIF83462.1 - 3.4e-26 91.3 7.4 7.1e-12 45.0 0.3 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 AIF83462.1 - 0.00025 20.9 0.1 0.049 13.5 0.0 2.6 3 0 0 3 3 3 2 Cupredoxin-like domain Zip PF02535.17 AIF83463.1 - 2.6e-08 33.2 10.5 2.6e-08 33.2 7.3 2.2 1 1 1 2 2 2 1 ZIP Zinc transporter Borrelia_P13 PF05628.7 AIF83463.1 - 2.6 7.8 7.5 2.1 8.1 2.9 2.4 1 1 1 2 2 2 0 Borrelia membrane protein P13 DUF217 PF02697.9 AIF83464.1 - 0.0015 18.7 0.2 0.0082 16.3 0.2 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, COG1753 DUF2393 PF09624.5 AIF83465.1 - 0.0054 16.2 0.4 0.8 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2393) DUF11 PF01345.13 AIF83465.1 - 0.023 14.7 1.4 0.084 12.9 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF11 CARDB PF07705.6 AIF83465.1 - 0.21 11.6 0.1 0.21 11.6 0.0 2.5 3 0 0 3 3 3 0 CARDB zinc_ribbon_5 PF13719.1 AIF83467.1 - 0.0096 15.4 3.7 0.31 10.6 0.4 2.4 2 0 0 2 2 2 2 zinc-ribbon domain Tmemb_55A PF09788.4 AIF83467.1 - 0.018 14.1 0.2 0.019 14.1 0.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_4 PF13717.1 AIF83467.1 - 0.16 11.6 4.5 2.6 7.8 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Cu-oxidase_3 PF07732.10 AIF83468.1 - 5.8e-12 45.3 0.4 1.4e-11 44.1 0.3 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AIF83468.1 - 6e-06 25.8 1.3 0.0021 17.5 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 AIF83468.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Cupredoxin-like domain Fer4_20 PF14691.1 AIF83472.1 - 9.9e-31 105.6 0.6 1.5e-30 105.0 0.4 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 AIF83472.1 - 7.7e-21 74.8 0.0 3.3e-20 72.8 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AIF83472.1 - 1.1e-11 44.9 1.2 2.4e-05 24.6 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIF83472.1 - 7e-08 32.3 0.1 1.6e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AIF83472.1 - 1.3e-07 31.8 0.0 0.0014 18.7 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AIF83472.1 - 1.5e-07 30.7 0.0 0.0008 18.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AIF83472.1 - 1.6e-06 27.2 1.8 0.0071 15.2 0.3 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 AIF83472.1 - 2.5e-06 26.7 0.3 1.4e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 AIF83472.1 - 1.6e-05 23.5 0.4 0.00022 19.8 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 AIF83472.1 - 0.00099 18.2 0.1 0.28 10.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 AIF83472.1 - 0.0015 18.7 0.1 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 AIF83472.1 - 0.0033 16.3 1.0 0.1 11.4 0.2 2.7 4 0 0 4 4 4 1 FAD binding domain NAD_binding_9 PF13454.1 AIF83472.1 - 0.0098 15.6 0.3 0.033 13.9 0.0 2.0 2 0 0 2 2 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.2 AIF83472.1 - 0.011 16.0 2.0 0.078 13.3 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIF83472.1 - 0.023 14.9 0.3 0.023 14.9 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.16 AIF83472.1 - 0.024 14.1 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 AIF83472.1 - 0.044 12.9 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_4 PF12800.2 AIF83472.1 - 0.056 13.7 0.9 0.056 13.7 0.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DJ-1_PfpI PF01965.19 AIF83472.1 - 0.066 12.6 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 DJ-1/PfpI family Fer4_10 PF13237.1 AIF83472.1 - 0.089 12.6 4.2 0.2 11.4 2.9 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 AIF83472.1 - 0.098 11.5 0.1 0.77 8.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 AIF83472.1 - 0.17 11.5 0.2 0.66 9.6 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fer4_8 PF13183.1 AIF83472.1 - 0.17 11.9 4.9 0.51 10.4 3.6 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIF83472.1 - 1.9 8.5 11.6 0.14 12.1 2.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 AIF83472.1 - 9.3 6.3 8.1 0.54 10.2 1.2 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain PKD PF00801.15 AIF83473.1 - 1.4e-15 56.7 1.5 2.5e-15 55.9 1.0 1.4 1 0 0 1 1 1 1 PKD domain Big_3_4 PF13754.1 AIF83473.1 - 5.5e-05 23.4 3.9 0.00011 22.4 2.7 1.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) GTP_EFTU_D2 PF03144.20 AIF83474.1 - 4.2e-08 33.1 0.2 1.1e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AIF83474.1 - 0.03 13.9 0.5 0.1 12.2 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF99 PF01949.11 AIF83475.1 - 1e-55 187.7 0.1 1.1e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 zf-C2H2 PF00096.21 AIF83476.1 - 1.1e-05 25.4 0.1 2.3e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF83476.1 - 3.5e-05 23.8 0.1 0.00018 21.5 0.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AIF83476.1 - 9.4e-05 22.4 0.3 0.00017 21.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AIF83476.1 - 0.0007 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 AIF83476.1 - 0.0032 17.6 0.1 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP21_like_P PF12230.3 AIF83476.1 - 0.034 13.6 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-H2C2_2 PF13465.1 AIF83476.1 - 0.052 13.8 1.8 0.14 12.4 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Fe-ADH_2 PF13685.1 AIF83477.1 - 1.7e-60 204.4 0.1 2.3e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 AIF83477.1 - 9.6e-24 83.6 0.7 3.4e-23 81.8 0.5 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 AIF83477.1 - 1.1e-07 31.0 0.1 1.9e-06 26.9 0.1 2.6 1 1 0 1 1 1 1 3-dehydroquinate synthase AIRC PF00731.15 AIF83477.1 - 0.038 13.2 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 AIR carboxylase TRAM PF01938.15 AIF83478.1 - 2.7e-11 43.0 0.3 3.8e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 TRAM domain Beta-Casp PF10996.3 AIF83479.1 - 1.5e-24 86.3 0.0 1.4e-23 83.2 0.0 2.5 2 1 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 AIF83479.1 - 1.2e-21 77.2 0.1 2e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIF83479.1 - 1.2e-11 44.5 0.0 2.8e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AIF83479.1 - 1.4e-10 40.8 0.0 3.7e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AIF83479.1 - 0.00092 18.9 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Trans_reg_C PF00486.23 AIF83479.1 - 0.12 12.3 0.0 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF552 PF04472.7 AIF83480.1 - 1.2e-16 60.4 0.1 1.3e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF552) FluMu_gp41 PF10109.4 AIF83480.1 - 0.045 13.6 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 Flu_M1_C PF08289.6 AIF83480.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain ThiI PF02568.9 AIF83481.1 - 3.7e-15 55.9 0.0 6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 AIF83481.1 - 1.2e-13 50.3 0.0 2.1e-11 42.9 0.0 2.2 2 1 0 2 2 2 2 tRNA methyl transferase DUF814 PF05670.8 AIF83481.1 - 2.4e-09 36.9 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Asn_synthase PF00733.16 AIF83481.1 - 4.1e-05 23.2 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AIF83481.1 - 0.0026 17.0 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC HTH_23 PF13384.1 AIF83481.1 - 0.047 13.3 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_8 PF02954.14 AIF83481.1 - 0.13 11.8 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family B5 PF03484.10 AIF83482.1 - 2.1e-19 69.1 0.0 5.1e-18 64.6 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain B3_4 PF03483.12 AIF83482.1 - 3.3e-13 49.4 0.0 5.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA-synt_2d PF01409.15 AIF83483.1 - 9.3e-85 283.7 0.0 1.2e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 AIF83483.1 - 6.3e-06 25.1 0.8 0.0012 17.6 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AIF83483.1 - 0.0029 17.1 0.1 0.0086 15.6 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_20 PF12840.2 AIF83483.1 - 0.013 15.2 0.1 0.048 13.4 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain CFIA_Pcf11 PF11526.3 AIF83483.1 - 0.028 14.5 0.1 0.091 12.9 0.1 1.8 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 HTH_24 PF13412.1 AIF83483.1 - 0.039 13.3 0.3 0.11 11.8 0.2 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding tRNA-synt_1b PF00579.20 AIF83484.1 - 3.5e-22 78.8 0.0 6e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 AIF83484.1 - 0.026 13.2 0.0 0.059 12.0 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) CTP_transf_2 PF01467.21 AIF83487.1 - 6.7e-12 45.7 0.1 1.9e-10 41.0 0.1 2.0 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 AIF83487.1 - 0.0065 16.1 0.3 0.016 14.8 0.1 1.7 2 0 0 2 2 2 1 FAD synthetase DUF2833 PF11090.3 AIF83487.1 - 0.051 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Fer4 PF00037.22 AIF83488.1 - 6.5e-08 31.8 23.1 9.5e-05 21.8 2.3 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 AIF83488.1 - 8.1e-07 29.2 6.8 8.1e-07 29.2 4.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 AIF83488.1 - 1.9e-06 28.1 9.2 1.9e-06 28.1 6.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF83488.1 - 3.5e-05 23.5 19.6 0.00014 21.5 6.5 2.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 AIF83488.1 - 6.7e-05 22.6 7.7 6.7e-05 22.6 5.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF83488.1 - 0.00015 21.7 6.0 0.00015 21.7 4.2 2.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 AIF83488.1 - 0.00057 20.2 7.3 0.076 13.4 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIF83488.1 - 0.0075 16.1 20.6 0.049 13.5 2.6 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.2 AIF83488.1 - 0.033 14.1 19.4 0.13 12.1 1.4 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.1 AIF83488.1 - 0.13 12.8 9.5 0.99 10.0 1.1 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.1 AIF83488.1 - 0.25 11.7 10.3 0.71 10.3 0.6 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.2 AIF83488.1 - 0.36 11.2 16.4 0.28 11.6 1.1 3.4 3 1 0 3 3 3 0 4Fe-4S binding domain DUF4139 PF13598.1 AIF83488.1 - 0.45 9.7 2.9 0.6 9.3 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Fer4_3 PF12798.2 AIF83488.1 - 1 10.1 24.3 0.28 11.8 2.4 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 AIF83488.1 - 1.2 9.5 12.6 2.1 8.7 0.3 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 AIF83488.1 - 5.7 7.7 15.2 1.3 9.8 1.6 2.8 2 1 2 4 4 3 0 4Fe-4S double cluster binding domain TPP_enzyme_N PF02776.13 AIF83489.1 - 2.8e-51 173.4 0.3 1.3e-49 168.0 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AIF83489.1 - 2.7e-42 143.9 0.4 1.5e-41 141.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AIF83489.1 - 9.8e-31 106.3 0.1 2.3e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 AIF83489.1 - 2e-05 24.2 0.3 4.2e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg VIT1 PF01988.14 AIF83490.1 - 1.3e-56 191.4 6.3 1.5e-56 191.2 4.4 1.0 1 0 0 1 1 1 1 VIT family DUF1049 PF06305.6 AIF83490.1 - 0.016 14.6 9.6 0.021 14.3 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1049) Carbpep_Y_N PF05388.6 AIF83490.1 - 0.019 15.1 0.1 0.041 14.0 0.1 1.6 1 1 0 1 1 1 0 Carboxypeptidase Y pro-peptide DUF1212 PF06738.7 AIF83490.1 - 0.081 12.3 3.2 0.13 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) HDAC4_Gln PF12203.3 AIF83490.1 - 0.15 11.9 1.4 0.25 11.3 0.9 1.2 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 TrmB PF01978.14 AIF83491.1 - 4.2e-16 58.3 0.3 3.4e-15 55.5 0.1 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AIF83491.1 - 5.6e-11 41.8 0.4 1.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB PLDc_2 PF13091.1 AIF83491.1 - 3.9e-05 23.4 0.2 0.16 11.6 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain HTH_5 PF01022.15 AIF83491.1 - 0.0012 18.4 0.1 0.0066 16.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR PF01047.17 AIF83491.1 - 0.0023 17.5 0.2 0.0083 15.8 0.2 2.0 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.5 AIF83491.1 - 0.0023 17.4 0.8 0.017 14.7 0.3 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.2 AIF83491.1 - 0.0031 17.1 0.2 0.016 14.8 0.1 2.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 AIF83491.1 - 0.016 15.2 0.2 0.056 13.5 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.1 AIF83491.1 - 0.018 14.3 0.3 0.1 12.0 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PadR PF03551.9 AIF83491.1 - 0.022 14.4 0.0 0.067 12.9 0.0 1.8 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.2 AIF83491.1 - 0.048 13.4 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 AIF83491.1 - 0.063 13.0 0.1 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Glyco_trans_4_4 PF13579.1 AIF83491.1 - 0.11 12.6 0.2 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Peptidase_M10 PF00413.19 AIF83492.1 - 1.6e-13 50.6 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 AIF83492.1 - 0.00024 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 AIF83492.1 - 0.00031 20.8 0.0 0.0005 20.1 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 AIF83492.1 - 0.00045 20.7 0.6 0.00085 19.8 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AIF83492.1 - 0.0013 18.6 0.1 0.0028 17.6 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M54 PF07998.6 AIF83492.1 - 0.0039 16.9 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M54 DUF45 PF01863.12 AIF83492.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Peptidase_M66 PF10462.4 AIF83492.1 - 0.017 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.3 AIF83492.1 - 0.019 14.3 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF3152 PF11350.3 AIF83492.1 - 0.024 14.1 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Astacin PF01400.19 AIF83492.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M43 PF05572.8 AIF83492.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Reprolysin PF01421.14 AIF83492.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Metallopep PF12044.3 AIF83492.1 - 0.15 10.5 0.5 0.25 9.7 0.1 1.4 2 0 0 2 2 2 0 Putative peptidase family Peptidase_M13 PF01431.16 AIF83492.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M13 MCLC PF05934.6 AIF83493.1 - 2.2 6.4 0.0 2.2 6.4 0.0 2.8 2 1 1 3 3 3 0 Mid-1-related chloride channel (MCLC) Nucleo_P87 PF07267.6 AIF83493.1 - 10 4.6 9.4 0.81 8.2 3.4 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 V4R PF02830.13 AIF83494.1 - 1.8e-11 43.6 0.2 3.7e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 V4R domain HTH_24 PF13412.1 AIF83494.1 - 0.00049 19.4 0.0 0.00094 18.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_CodY PF08222.6 AIF83494.1 - 0.0025 17.1 0.1 0.0074 15.6 0.1 1.8 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_20 PF12840.2 AIF83494.1 - 0.0041 16.8 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.1 AIF83494.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 AIF83494.1 - 0.032 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.1 AIF83494.1 - 0.045 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_5 PF01022.15 AIF83494.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF4085 PF13315.1 AIF83494.1 - 0.094 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Cro PF09048.5 AIF83494.1 - 0.22 11.1 0.8 2.4 7.8 0.0 3.0 4 0 0 4 4 4 0 Cro DUF1469 PF07332.6 AIF83495.1 - 0.025 14.3 0.2 0.028 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF3681 PF12442.3 AIF83495.1 - 0.029 14.5 0.4 0.032 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) YbgS PF13985.1 AIF83495.1 - 0.38 10.6 3.3 0.43 10.4 2.3 1.1 1 0 0 1 1 1 0 YbgS-like protein TPPK_C PF12555.3 AIF83495.1 - 1.3 8.7 5.1 3.8 7.3 3.5 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Big_3 PF07523.7 AIF83497.1 - 0.09 12.8 1.0 0.18 11.8 0.3 1.9 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) AWPM-19 PF05512.6 AIF83498.1 - 0.0098 15.8 0.1 0.27 11.2 0.0 2.2 2 1 0 2 2 2 2 AWPM-19-like family PKD PF00801.15 AIF83499.1 - 2.6e-18 65.5 73.8 9.1e-05 22.1 1.7 8.8 8 0 0 8 8 8 6 PKD domain HemolysinCabind PF00353.14 AIF83499.1 - 1e-09 37.9 133.6 0.00067 19.8 3.9 14.2 11 2 3 16 16 16 11 Hemolysin-type calcium-binding repeat (2 copies) Y_Y_Y PF07495.8 AIF83499.1 - 0.00029 20.5 1.8 0.54 10.0 0.0 4.2 4 0 0 4 4 4 2 Y_Y_Y domain SLT_2 PF13406.1 AIF83499.1 - 0.015 14.2 1.0 0.77 8.6 0.0 3.5 4 0 0 4 4 4 0 Transglycosylase SLT domain PKD PF00801.15 AIF83500.1 - 7.4e-12 44.8 29.2 1.8e-05 24.4 4.4 4.6 4 0 0 4 4 4 4 PKD domain HemolysinCabind PF00353.14 AIF83500.1 - 5.1e-07 29.4 63.7 0.0017 18.5 0.8 8.1 7 1 2 9 9 9 4 Hemolysin-type calcium-binding repeat (2 copies) TcdB_toxin_midN PF12256.3 AIF83500.1 - 0.02 14.3 4.1 0.85 9.0 0.0 3.3 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region VCBS PF13517.1 AIF83500.1 - 0.028 14.7 19.8 0.26 11.6 0.2 5.6 5 1 1 6 6 6 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 AIF83500.1 - 1.1 9.1 14.7 35 4.2 0.0 5.8 5 1 0 5 5 5 0 FG-GAP repeat DUF11 PF01345.13 AIF83502.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF11 HATPase_c PF02518.21 AIF83503.1 - 1.8e-25 88.7 0.1 3.5e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF83503.1 - 5e-12 45.6 0.5 1.4e-11 44.1 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AIF83503.1 - 0.00018 21.2 0.1 0.00057 19.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AIF83503.1 - 0.0025 17.6 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.1 AIF83503.1 - 0.0026 17.4 0.0 0.0088 15.7 0.0 1.9 1 0 0 1 1 1 1 GHKL domain Cache_1 PF02743.13 AIF83503.1 - 0.0096 15.4 0.0 0.03 13.8 0.0 1.9 1 0 0 1 1 1 1 Cache domain DUF3227 PF11537.3 AIF83504.1 - 0.0069 16.4 0.0 0.0088 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3227) SicP-binding PF09119.5 AIF83504.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 SicP binding Zn-ribbon_8 PF09723.5 AIF83505.1 - 0.00015 21.6 16.4 0.0087 15.9 0.9 4.3 3 1 1 4 4 4 2 Zinc ribbon domain zf-P11 PF03854.9 AIF83505.1 - 0.021 14.2 1.5 0.26 10.8 1.0 2.4 2 0 0 2 2 2 0 P-11 zinc finger DUF35_N PF12172.3 AIF83505.1 - 0.023 14.5 8.2 0.14 12.1 0.2 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ribosomal_L37ae PF01780.14 AIF83505.1 - 0.034 14.0 2.5 0.33 10.8 0.5 2.4 1 1 1 2 2 2 0 Ribosomal L37ae protein family C1_1 PF00130.17 AIF83505.1 - 0.04 13.6 4.2 0.3 10.8 0.3 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_3 PF14369.1 AIF83505.1 - 0.2 11.7 3.8 20 5.2 0.0 3.4 3 0 0 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 AIF83505.1 - 0.24 11.1 9.3 2.9 7.7 1.1 3.1 1 1 2 3 3 3 0 zinc-ribbons A2L_zn_ribbon PF08792.5 AIF83505.1 - 0.37 10.2 10.0 0.15 11.5 0.3 3.6 4 0 0 4 4 4 0 A2L zinc ribbon domain DZR PF12773.2 AIF83505.1 - 0.66 9.8 9.8 39 4.1 6.9 2.6 1 1 0 1 1 1 0 Double zinc ribbon zf-AN1 PF01428.11 AIF83505.1 - 0.67 9.8 11.0 5.8 6.8 0.9 3.0 2 1 1 3 3 3 0 AN1-like Zinc finger OrfB_Zn_ribbon PF07282.6 AIF83505.1 - 0.86 9.3 9.6 0.047 13.3 1.1 2.5 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-C3HC4_3 PF13920.1 AIF83505.1 - 1.6 8.4 8.8 0.69 9.6 0.3 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 AIF83505.1 - 1.7 8.8 5.2 5.9 7.0 1.6 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-IS66 PF13005.2 AIF83505.1 - 2 8.4 0.0 2 8.4 0.0 3.9 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-C2H2 PF00096.21 AIF83505.1 - 2.3 8.7 17.0 3.9 7.9 0.8 3.9 4 0 0 4 4 3 0 Zinc finger, C2H2 type Sgf11 PF08209.6 AIF83505.1 - 5.9 6.3 15.4 2.8 7.3 0.1 4.0 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) FYVE PF01363.16 AIF83505.1 - 6.1 6.8 7.3 25 4.8 0.0 2.5 2 1 0 2 2 2 0 FYVE zinc finger TF_Zn_Ribbon PF08271.7 AIF83505.1 - 6.6 6.1 11.5 29 4.0 2.9 4.1 3 1 0 3 3 3 0 TFIIB zinc-binding Opy2 PF09463.5 AIF83505.1 - 6.9 6.8 7.6 77 3.4 0.1 3.4 3 0 0 3 3 3 0 Opy2 protein CpXC PF14353.1 AIF83505.1 - 9.2 6.2 7.6 5.7 6.9 0.7 3.0 3 0 0 3 3 3 0 CpXC protein Glyco_tranf_2_3 PF13641.1 AIF83506.1 - 2.6e-38 132.0 0.0 3.5e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AIF83506.1 - 4.1e-25 88.6 2.0 4.1e-25 88.6 1.4 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 AIF83506.1 - 1.4e-14 54.1 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AIF83506.1 - 3.7e-08 32.8 0.1 7.8e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF83506.1 - 6.7e-06 25.3 0.0 1.2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.9 AIF83506.1 - 0.029 12.6 1.1 0.67 8.1 0.2 2.5 2 1 1 3 3 3 0 Cellulose synthase Response_reg PF00072.19 AIF83507.1 - 7.9e-24 83.8 0.3 1.3e-22 79.8 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain Nucleocap_ssRNA PF11128.3 AIF83507.1 - 0.00031 20.2 0.1 0.4 10.1 0.1 2.6 2 1 0 3 3 3 2 Plant viral coat protein nucleocapsid UPF0180 PF03698.8 AIF83507.1 - 0.014 15.2 0.1 5.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) Thy1 PF02511.10 AIF83508.1 - 5.4e-32 110.6 0.0 3.8e-19 68.7 1.0 2.7 2 1 0 2 2 2 2 Thymidylate synthase complementing protein DUF747 PF05346.6 AIF83509.1 - 0.028 13.4 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic membrane protein family DASH_Dad1 PF08649.5 AIF83509.1 - 0.035 13.7 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad1 DUF2365 PF10157.4 AIF83509.1 - 0.084 12.7 0.8 0.68 9.8 0.1 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Viral_DNA_Zn_bi PF03728.8 AIF83509.1 - 0.12 12.4 0.6 0.18 11.8 0.4 1.3 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain SseC PF04888.7 AIF83509.1 - 0.18 11.1 2.8 0.25 10.6 0.2 1.9 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family IFT20 PF14931.1 AIF83509.1 - 0.21 11.4 2.9 1.7 8.5 0.1 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 PRC PF05239.11 AIF83510.1 - 0.0088 15.8 1.1 0.025 14.4 0.8 1.7 1 0 0 1 1 1 1 PRC-barrel domain DUF724 PF05266.9 AIF83510.1 - 0.36 10.4 7.5 0.31 10.6 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) MGC-24 PF05283.6 AIF83510.1 - 1.1 8.9 11.0 1.7 8.4 7.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Mucin PF01456.12 AIF83510.1 - 2.1 8.1 16.3 3.2 7.5 11.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein COX1 PF00115.15 AIF83511.1 - 1.8e-140 468.4 59.4 2.5e-140 468.0 41.2 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF2214 PF09980.4 AIF83512.1 - 0.17 11.6 2.9 0.38 10.5 0.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2214) Flavin_Reduct PF01613.13 AIF83513.1 - 1.7e-27 96.1 0.0 2.8e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 AIF83513.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Aminotran_3 PF00202.16 AIF83514.1 - 2.8e-60 203.9 0.0 4.7e-60 203.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AIF83514.1 - 0.00045 19.2 0.0 0.0032 16.4 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Eclosion PF04736.7 AIF83515.1 - 0.14 11.5 0.5 0.18 11.2 0.3 1.2 1 0 0 1 1 1 0 Eclosion hormone DUF2387 PF09526.5 AIF83515.1 - 0.3 11.0 1.9 0.24 11.3 0.2 1.6 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Cyclotide PF03784.8 AIF83515.1 - 1.4 8.8 4.6 0.24 11.2 0.7 1.5 2 0 0 2 2 2 0 Cyclotide family DUF4199 PF13858.1 AIF83516.1 - 0.041 13.8 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2678 PF10856.3 AIF83516.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) ResIII PF04851.10 AIF83518.1 - 1.2e-13 51.3 0.0 4.4e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AIF83518.1 - 2.1e-10 40.3 0.1 8.8e-10 38.3 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIF83518.1 - 7.2e-08 32.1 0.0 1.8e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 AIF83518.1 - 0.00021 20.9 1.3 0.098 12.2 0.3 3.2 3 1 0 3 3 3 2 AAA domain DUF2075 PF09848.4 AIF83518.1 - 0.0066 15.4 0.1 0.037 12.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF367 PF04034.8 AIF83519.1 - 2e-38 130.8 0.0 2.5e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AIF83519.1 - 0.0011 18.4 0.1 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF3574 PF12098.3 AIF83520.1 - 0.0024 17.4 0.0 0.0025 17.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3574) DUF4307 PF14155.1 AIF83522.1 - 0.2 11.4 1.3 0.35 10.6 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4307) Nol1_Nop2_Fmu PF01189.12 AIF83523.1 - 3.2e-66 223.6 0.0 3.7e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AIF83523.1 - 5.1e-06 26.5 0.0 8.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF83523.1 - 0.00076 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF83523.1 - 0.0015 19.1 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain POR PF01558.13 AIF83523.1 - 0.003 17.5 0.0 0.0071 16.2 0.0 1.6 1 1 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FtsJ PF01728.14 AIF83523.1 - 0.0065 16.4 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 AIF83523.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0113 PF03657.8 AIF83524.1 - 7.8e-24 84.1 0.0 9.2e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 AIF83524.1 - 9.8e-10 38.0 0.1 2.2e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 PUA domain HTH_7 PF02796.10 AIF83525.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 AIF83525.1 - 0.0074 15.8 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 AIF83525.1 - 0.05 13.2 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_39 PF14090.1 AIF83525.1 - 0.073 12.5 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF433 PF04255.9 AIF83525.1 - 0.077 12.4 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF433) HTH_28 PF13518.1 AIF83525.1 - 0.092 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2316 PF10078.4 AIF83525.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) UPF0052 PF01933.13 AIF83527.1 - 1.4e-46 159.1 0.0 1.7e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CofC PF01983.11 AIF83528.1 - 2.3e-27 95.4 0.1 2.9e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.2 AIF83528.1 - 1.3e-06 28.5 0.7 1.7e-06 28.1 0.5 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 AIF83528.1 - 0.0017 17.9 0.1 0.0078 15.8 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase ADH_zinc_N PF00107.21 AIF83528.1 - 0.005 16.3 0.2 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2064 PF09837.4 AIF83528.1 - 0.12 12.0 0.4 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Phage-tail_3 PF13550.1 AIF83528.1 - 2.5 7.8 5.8 8.6 6.1 0.2 2.9 2 1 2 4 4 4 0 Putative phage tail protein Mrr_cat PF04471.7 AIF83530.1 - 6e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease NERD PF08378.6 AIF83530.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Nuclease-related domain S4 PF01479.20 AIF83530.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 S4 domain DUF2070 PF09843.4 AIF83531.1 - 1.7e-32 112.3 0.2 2.7e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Sec61_beta PF03911.11 AIF83532.1 - 2.5e-13 49.5 0.4 2.8e-13 49.3 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family Auto_anti-p27 PF06677.7 AIF83533.1 - 5.6e-08 32.4 0.5 1e-07 31.5 0.3 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2HC5 PF06221.8 AIF83533.1 - 0.0081 15.8 0.8 0.013 15.2 0.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type OrfB_Zn_ribbon PF07282.6 AIF83533.1 - 0.18 11.4 0.9 0.32 10.6 0.7 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 AIF83533.1 - 0.48 9.6 3.6 12 5.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 AIF83533.1 - 1.3 9.3 5.1 6 7.2 3.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 AIF83533.1 - 1.8 8.1 6.1 15 5.2 0.9 2.1 1 1 2 3 3 3 0 zinc-ribbon domain SUI1 PF01253.17 AIF83534.1 - 9.8e-23 79.7 0.1 1.2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 CHASE PF03924.8 AIF83535.1 - 9.6e-59 197.8 0.6 1.9e-58 196.8 0.4 1.5 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.21 AIF83535.1 - 1.4e-29 101.9 0.2 5.4e-29 100.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF83535.1 - 6.5e-13 48.4 0.1 4.4e-12 45.7 0.0 2.3 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AIF83535.1 - 6.3e-07 29.1 0.1 1.7e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.20 AIF83535.1 - 2.4e-05 24.3 0.4 2.4e-05 24.3 0.3 2.5 2 0 0 2 2 2 1 HAMP domain Bul1_C PF04426.7 AIF83535.1 - 0.0051 16.0 0.1 0.19 10.9 0.0 2.3 1 1 1 2 2 2 1 Bul1 C terminus IncA PF04156.9 AIF83535.1 - 0.024 14.2 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 IncA protein DUF2189 PF09955.4 AIF83535.1 - 0.058 13.3 3.4 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) TFIIB PF00382.14 AIF83537.1 - 3.7e-37 125.9 7.1 3.2e-18 65.2 0.4 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AIF83537.1 - 1.1e-13 50.2 1.5 1.8e-13 49.5 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 AIF83537.1 - 0.00018 20.6 2.5 0.00036 19.6 1.8 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Sigma70_r4 PF04545.11 AIF83537.1 - 0.0002 20.5 0.0 0.011 15.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.18 AIF83537.1 - 0.00066 19.2 0.1 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AIF83537.1 - 0.0019 18.1 0.1 1 9.3 0.0 2.4 2 1 0 2 2 2 2 Cyclin, C-terminal domain HTH_AsnC-type PF13404.1 AIF83537.1 - 0.005 16.3 0.0 0.32 10.5 0.0 2.9 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain DZR PF12773.2 AIF83537.1 - 0.016 14.9 0.6 0.035 13.9 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon HTH_3 PF01381.17 AIF83537.1 - 0.023 14.5 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix LacI PF00356.16 AIF83537.1 - 0.029 13.9 3.0 0.54 9.9 0.1 3.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.1 AIF83537.1 - 0.036 13.7 0.0 0.68 9.6 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.7 AIF83537.1 - 0.061 12.9 0.1 5 6.8 0.0 2.6 2 0 0 2 2 2 0 HTH domain Sigma70_r4_2 PF08281.7 AIF83537.1 - 0.063 12.7 0.2 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Rrf2 PF02082.15 AIF83537.1 - 0.068 13.2 0.4 23 5.1 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator Lar_restr_allev PF14354.1 AIF83537.1 - 0.079 13.2 0.6 0.24 11.7 0.4 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 AIF83537.1 - 0.12 11.8 4.2 1.6 8.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S27e PF01667.12 AIF83537.1 - 0.13 11.8 1.0 0.22 11.1 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 MerR PF00376.18 AIF83537.1 - 0.14 11.7 0.1 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 MerR family regulatory protein OrfB_Zn_ribbon PF07282.6 AIF83537.1 - 0.26 10.9 1.3 0.61 9.7 0.9 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CCHC_5 PF14787.1 AIF83537.1 - 0.94 9.0 3.9 2.9 7.4 2.4 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Rib_5-P_isom_A PF06026.9 AIF83540.1 - 1.6e-51 174.0 0.0 2e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 AIF83540.1 - 3e-06 26.9 0.1 0.0087 15.7 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 AIF83540.1 - 0.0032 16.3 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain MscL PF01741.13 AIF83541.1 - 8.8e-21 74.3 3.0 1e-20 74.1 2.1 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FtsX PF02687.16 AIF83541.1 - 0.00077 19.2 4.2 0.001 18.8 2.9 1.1 1 0 0 1 1 1 1 FtsX-like permease family NPCC PF08058.6 AIF83541.1 - 0.027 14.3 0.3 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 Nuclear pore complex component Colicin_V PF02674.11 AIF83541.1 - 0.9 9.3 8.0 2.2 8.1 5.5 1.6 1 1 0 1 1 1 0 Colicin V production protein Amidohydro_4 PF13147.1 AIF83542.1 - 8.9e-29 101.3 0.0 1.4e-28 100.7 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 AIF83542.1 - 8.6e-14 51.1 0.0 2.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 AIF83542.1 - 3.4e-11 43.4 0.0 3.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 AIF83542.1 - 1e-07 31.5 0.1 0.0034 16.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 AIF83542.1 - 5.2e-05 23.3 0.1 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain zf-C3HC4_3 PF13920.1 AIF83543.1 - 0.0035 16.9 0.6 0.0047 16.5 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 AIF83543.1 - 0.017 14.9 0.9 0.026 14.3 0.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 AIF83543.1 - 0.051 13.5 2.3 0.091 12.7 1.6 1.4 1 0 0 1 1 1 0 zinc-finger FYVE PF01363.16 AIF83543.1 - 0.062 13.2 0.2 0.095 12.6 0.1 1.2 1 0 0 1 1 1 0 FYVE zinc finger zf-ribbon_3 PF13248.1 AIF83543.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Polysacc_deac_1 PF01522.16 AIF83547.1 - 9e-12 44.7 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 AIF83547.1 - 0.00065 18.7 0.0 0.00089 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CPSase_L_D2 PF02786.12 AIF83547.1 - 0.023 13.9 0.0 0.058 12.6 0.0 1.5 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PAS_8 PF13188.1 AIF83547.1 - 0.031 14.1 0.0 2.6 8.0 0.0 2.6 1 1 1 2 2 2 0 PAS domain HTH_45 PF14947.1 AIF83548.1 - 2.1e-18 65.8 0.1 2.6e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF83548.1 - 0.0018 17.8 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) CHB_HEX_C PF03174.8 AIF83549.1 - 1.1e-101 332.7 78.2 5.8e-22 77.3 8.0 6.8 6 0 0 6 6 6 5 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 AIF83549.1 - 4.8e-86 282.5 78.6 1e-18 66.8 4.3 8.0 8 0 0 8 8 8 5 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIF83549.1 - 2.9e-82 270.6 66.0 7.7e-18 64.3 3.6 6.9 6 0 0 6 6 6 5 Fn3 associated Polysacc_deac_1 PF01522.16 AIF83549.1 - 2.2e-12 46.6 0.4 1.3e-11 44.1 0.0 2.5 3 0 0 3 3 3 1 Polysaccharide deacetylase HYR PF02494.11 AIF83549.1 - 2.2e-11 43.5 21.2 2.6e-08 33.7 0.9 5.4 4 1 0 4 4 4 2 HYR domain SWM_repeat PF13753.1 AIF83549.1 - 8.4e-06 25.0 12.8 8.4e-06 25.0 8.9 7.4 1 1 4 6 6 6 2 Putative flagellar system-associated repeat Big_3_4 PF13754.1 AIF83549.1 - 0.0049 17.1 10.9 0.0049 17.1 7.5 12.7 10 2 2 12 12 12 3 Bacterial Ig-like domain (group 3) Qn_am_d_aIII PF09099.5 AIF83550.1 - 1.9e-05 24.8 1.6 0.075 13.3 0.4 2.8 2 1 0 2 2 2 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III TIG PF01833.19 AIF83550.1 - 0.0017 18.3 23.6 0.018 15.0 3.1 3.6 2 1 1 3 3 3 2 IPT/TIG domain A2M_N PF01835.14 AIF83550.1 - 0.005 17.0 2.5 0.25 11.6 0.0 3.0 4 0 0 4 4 4 1 MG2 domain NPCBM_assoc PF10633.4 AIF83550.1 - 0.01 15.8 0.8 0.01 15.8 0.5 4.8 3 2 1 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase CarboxypepD_reg PF13620.1 AIF83550.1 - 0.015 15.3 2.9 0.015 15.3 2.0 3.6 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain DUF4625 PF15418.1 AIF83550.1 - 0.04 14.0 0.1 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Alph_Pro_TM PF09608.5 AIF83550.1 - 0.1 12.1 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) PhnH PF05845.7 AIF83550.1 - 3.2 7.1 10.5 3.5 7.0 0.0 4.2 4 1 1 5 5 5 0 Bacterial phosphonate metabolism protein (PhnH) DUF4112 PF13430.1 AIF83551.1 - 0.0065 16.3 0.7 1.4 8.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4112) DER1 PF04511.10 AIF83551.1 - 0.017 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Der1-like family Dicistro_VP4 PF11492.3 AIF83551.1 - 0.086 12.8 1.0 5.3 7.1 0.1 2.3 1 1 1 2 2 2 0 Cricket paralysis virus, VP4 Patatin PF01734.17 AIF83553.1 - 2.3e-12 47.2 0.0 1.1e-11 45.0 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Response_reg PF00072.19 AIF83554.1 - 3.3e-20 72.1 0.1 4.9e-20 71.6 0.1 1.2 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AIF83555.1 - 1.8e-23 82.3 1.0 5.3e-23 80.8 0.2 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF83555.1 - 2.1e-13 50.0 1.7 7.7e-13 48.2 1.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PLDc_2 PF13091.1 AIF83555.1 - 0.00062 19.5 0.2 0.34 10.6 0.0 3.7 3 0 0 3 3 3 1 PLD-like domain Response_reg PF00072.19 AIF83556.1 - 1.4e-17 63.6 0.0 2.6e-16 59.6 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain Guanylate_cyc PF00211.15 AIF83556.1 - 2.9e-11 43.0 0.0 4.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.19 AIF83557.1 - 7.3e-20 71.0 0.0 1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_45 PF14947.1 AIF83557.1 - 1.2e-07 31.3 0.1 2.3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.1 AIF83557.1 - 7.9e-05 21.9 0.2 0.00031 20.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF83557.1 - 0.037 13.5 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SBP_bac_8 PF13416.1 AIF83558.1 - 1.1e-27 97.4 1.3 1.9e-27 96.6 0.9 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 AIF83558.1 - 3.5e-25 89.3 2.5 6.6e-25 88.5 1.8 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein HATPase_c PF02518.21 AIF83559.1 - 2.5e-24 85.1 0.1 4.6e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF83559.1 - 1.9e-14 53.3 1.8 3.2e-14 52.6 0.5 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AIF83559.1 - 0.00037 20.1 0.2 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 AIF83559.1 - 0.023 14.3 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AIF83559.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Opi1 PF08618.5 AIF83560.1 - 0.029 13.3 0.1 0.032 13.1 0.1 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 DUF1722 PF08349.6 AIF83560.1 - 0.06 13.2 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) GP41 PF00517.12 AIF83560.1 - 0.08 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein zf-C2H2_2 PF12756.2 AIF83561.1 - 7.3e-06 26.0 0.6 8e-06 25.8 0.4 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 AIF83561.1 - 0.0012 18.9 0.1 0.0023 18.1 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AIF83561.1 - 0.026 14.6 0.5 0.047 13.8 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 AIF83561.1 - 0.058 13.7 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.2 AIF83561.1 - 0.058 13.6 0.2 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ERCC4 PF02732.10 AIF83562.1 - 0.087 12.5 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 ERCC4 domain DUF2228 PF10228.4 AIF83562.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Malic_M PF03949.10 AIF83563.1 - 6.8e-60 202.7 0.3 9.4e-60 202.2 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AIF83563.1 - 8e-21 74.4 2.8 3.6e-18 65.7 0.1 2.8 2 1 1 3 3 3 2 Malic enzyme, N-terminal domain ELFV_dehydrog PF00208.16 AIF83563.1 - 2.2e-05 24.1 1.1 0.00024 20.7 0.3 2.2 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.16 AIF83563.1 - 0.00012 21.9 1.4 0.007 16.2 0.0 3.0 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.14 AIF83563.1 - 0.0024 16.9 0.1 0.0037 16.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 AIF83563.1 - 0.0089 16.1 0.6 0.36 10.9 0.1 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 AIF83563.1 - 0.014 15.0 0.9 0.025 14.2 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 AIF83563.1 - 0.028 13.9 1.4 0.11 12.0 0.4 2.2 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 AIF83563.1 - 0.11 12.4 2.7 0.22 11.5 0.2 2.7 2 2 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 AIF83563.1 - 1 9.1 4.7 0.33 10.7 0.3 2.4 3 1 0 3 3 3 0 ThiF family zf-C2H2_4 PF13894.1 AIF83564.1 - 2e-06 27.6 13.9 9.8e-05 22.4 0.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF83564.1 - 5.3e-06 26.4 13.5 0.0042 17.3 0.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AIF83564.1 - 0.00011 21.9 4.2 0.0062 16.3 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 AIF83564.1 - 0.0092 15.6 2.9 0.11 12.2 2.0 2.2 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF83564.1 - 0.01 15.3 3.3 0.12 12.0 2.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-trcl PF13451.1 AIF83564.1 - 0.018 14.6 2.4 0.14 11.8 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain DUF629 PF04780.7 AIF83564.1 - 0.031 12.8 7.7 0.037 12.5 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) LIM PF00412.17 AIF83564.1 - 0.034 14.2 4.0 0.066 13.2 2.7 1.6 1 1 0 1 1 1 0 LIM domain RNA_POL_M_15KD PF02150.11 AIF83564.1 - 0.052 13.2 2.1 2.8 7.7 1.2 2.5 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.5 AIF83564.1 - 0.091 12.7 3.8 2.6 8.0 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.1 AIF83564.1 - 0.1 12.3 3.9 3.5 7.4 0.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Terminase_GpA PF05876.7 AIF83564.1 - 0.15 10.3 3.0 0.16 10.3 2.1 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DNA_RNApol_7kD PF03604.8 AIF83564.1 - 0.15 11.5 1.7 0.37 10.2 0.2 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FUR PF01475.14 AIF83564.1 - 0.2 11.5 3.7 0.24 11.3 2.6 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family YhfH PF14149.1 AIF83564.1 - 0.21 11.4 1.9 0.57 10.0 0.2 2.1 2 0 0 2 2 2 0 YhfH-like protein zf-LYAR PF08790.6 AIF83564.1 - 0.26 11.0 3.5 7 6.4 0.3 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger RRN7 PF11781.3 AIF83564.1 - 0.29 10.6 2.1 0.37 10.3 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 AIF83564.1 - 0.29 10.9 2.6 0.62 9.9 1.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon XPA_N PF01286.13 AIF83564.1 - 0.37 10.4 3.3 1 9.1 0.2 2.3 2 0 0 2 2 2 0 XPA protein N-terminal HypA PF01155.14 AIF83564.1 - 0.37 10.4 2.3 1.7 8.3 1.5 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-HYPF PF07503.7 AIF83564.1 - 0.38 10.1 4.7 0.87 9.0 0.7 2.3 2 0 0 2 2 2 0 HypF finger DUF4606 PF15379.1 AIF83564.1 - 0.5 10.4 4.7 0.75 9.8 2.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) zf-C2H2_jaz PF12171.3 AIF83564.1 - 0.63 10.2 6.2 1.4 9.1 0.6 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AIF83564.1 - 0.88 9.7 9.6 0.38 10.8 0.4 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Evr1_Alr PF04777.8 AIF83564.1 - 1.8 8.4 5.2 7.2 6.5 0.3 2.1 1 1 1 2 2 2 0 Erv1 / Alr family zf-CHY PF05495.7 AIF83564.1 - 2.8 8.1 8.6 4 7.6 5.9 1.4 1 1 0 1 1 1 0 CHY zinc finger FYVE PF01363.16 AIF83564.1 - 3.2 7.7 7.7 1.8 8.5 1.4 2.2 1 1 1 2 2 2 0 FYVE zinc finger HNH PF01844.18 AIF83564.1 - 6.5 6.7 9.4 0.62 9.9 0.9 2.4 2 0 0 2 2 2 0 HNH endonuclease PHD PF00628.24 AIF83564.1 - 9.3 6.0 7.6 7.8 6.2 0.4 2.3 2 0 0 2 2 2 0 PHD-finger LEDGF PF11467.3 AIF83565.1 - 0.029 14.0 0.2 0.086 12.5 0.0 1.9 2 1 1 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) Plasmid_parti PF01672.11 AIF83565.1 - 0.041 14.3 0.1 3.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Putative plasmid partition protein FtsH_ext PF06480.10 AIF83565.1 - 3.6 7.7 6.1 1.8e+02 2.3 4.2 2.9 1 1 0 1 1 1 0 FtsH Extracellular HTH_45 PF14947.1 AIF83566.1 - 4.2e-09 36.0 0.0 5.1e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.1 AIF83566.1 - 0.00096 19.4 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.1 AIF83566.1 - 0.0061 15.9 0.1 0.011 15.1 0.1 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HemN_C PF06969.11 AIF83566.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain CBP4 PF07960.6 AIF83567.1 - 0.11 12.1 0.6 0.17 11.4 0.3 1.5 1 1 0 1 1 1 0 CBP4 DUF1469 PF07332.6 AIF83567.1 - 0.11 12.2 0.7 1 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Peptidase_M50 PF02163.17 AIF83568.1 - 0.068 12.1 0.8 0.095 11.6 0.3 1.5 1 1 1 2 2 2 0 Peptidase family M50 Peptidase_M50B PF13398.1 AIF83568.1 - 0.61 9.4 10.6 1.1 8.6 7.4 1.5 1 1 0 1 1 1 0 Peptidase M50B-like Zip PF02535.17 AIF83569.1 - 1.2e-09 37.6 18.9 3.4e-07 29.5 4.9 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter AzlD PF05437.7 AIF83569.1 - 0.0056 16.5 4.7 0.0056 16.5 3.3 2.7 3 0 0 3 3 3 2 Branched-chain amino acid transport protein (AzlD) PEMT PF04191.8 AIF83569.1 - 1.3 9.1 10.1 0.7 10.0 0.6 3.2 4 0 0 4 4 4 0 Phospholipid methyltransferase dCMP_cyt_deam_1 PF00383.17 AIF83570.1 - 3.2e-05 23.4 0.0 7.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DctQ PF04290.7 AIF83571.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component ETRAMP PF09716.5 AIF83571.1 - 0.2 11.6 2.2 0.31 11.0 1.5 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Cache_1 PF02743.13 AIF83573.1 - 0.081 12.4 0.3 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Cache domain Acetyltransf_1 PF00583.19 AIF83574.1 - 4.6e-09 36.1 0.4 1.5e-08 34.5 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIF83574.1 - 9.9e-07 28.8 0.2 2.8e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AIF83574.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AIF83574.1 - 0.0016 18.5 0.0 0.0058 16.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIF83574.1 - 0.0084 15.9 0.0 0.033 14.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AIF83574.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pribosyltran PF00156.22 AIF83575.1 - 8.1e-16 57.8 0.2 1.7e-15 56.8 0.1 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF257 PF03192.8 AIF83575.1 - 0.08 12.2 0.2 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 Zn_Tnp_IS1595 PF12760.2 AIF83576.1 - 0.00086 19.0 1.7 0.00097 18.8 1.1 1.1 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF83576.1 - 0.0014 18.2 3.5 0.0033 16.9 2.4 1.5 1 1 0 1 1 1 1 zinc-ribbon domain DUF2387 PF09526.5 AIF83576.1 - 0.0018 18.1 0.4 0.0022 17.8 0.3 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) zinc_ribbon_4 PF13717.1 AIF83576.1 - 0.0041 16.7 4.2 0.014 15.0 2.9 1.7 1 1 0 1 1 1 1 zinc-ribbon domain UPF0515 PF15135.1 AIF83576.1 - 0.0086 15.1 1.3 0.0087 15.1 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 Zn_Tnp_IS1 PF03811.8 AIF83576.1 - 0.015 14.8 2.5 0.032 13.7 1.7 1.6 1 1 0 1 1 1 0 InsA N-terminal domain FANCL_C PF11793.3 AIF83576.1 - 0.034 14.1 0.6 0.93 9.4 0.0 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain OrfB_Zn_ribbon PF07282.6 AIF83576.1 - 0.088 12.4 1.0 0.12 12.0 0.7 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.7 AIF83576.1 - 0.1 12.6 0.6 0.12 12.4 0.4 1.1 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-rbx1 PF12678.2 AIF83576.1 - 0.12 12.5 0.2 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 AIF83576.1 - 0.12 12.1 1.8 0.28 11.0 1.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 AIF83576.1 - 0.15 11.9 0.9 2.7 7.9 0.0 2.0 2 0 0 2 2 2 0 Ring finger domain Zn-ribbon_8 PF09723.5 AIF83576.1 - 0.21 11.5 3.0 9.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.1 AIF83576.1 - 0.21 11.2 2.6 1.5 8.5 0.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Mss51 PF13824.1 AIF83576.1 - 0.23 11.3 1.1 0.3 10.9 0.8 1.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3797 PF12677.2 AIF83576.1 - 0.32 10.6 2.4 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DUF4182 PF13790.1 AIF83576.1 - 0.37 10.6 2.6 0.58 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) DnaJ_CXXCXGXG PF00684.14 AIF83576.1 - 0.41 10.7 3.9 1.1 9.3 2.7 1.6 1 1 0 1 1 1 0 DnaJ central domain C1_4 PF07975.7 AIF83576.1 - 0.51 10.3 4.4 5.5 7.0 3.0 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zf-RING_5 PF14634.1 AIF83576.1 - 1 9.1 4.8 6 6.6 3.7 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-H2C2_2 PF13465.1 AIF83576.1 - 1 9.7 5.4 9.3 6.7 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-TFIIB PF13453.1 AIF83576.1 - 1 8.5 3.3 1.7 7.9 2.3 1.3 1 1 0 1 1 1 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.14 AIF83576.1 - 1.1 8.8 7.0 0.36 10.3 2.4 1.9 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PhnA_Zn_Ribbon PF08274.7 AIF83576.1 - 1.2 9.0 3.9 3.1 7.6 2.7 1.7 1 1 0 1 1 1 0 PhnA Zinc-Ribbon DUF2296 PF10058.4 AIF83576.1 - 1.2 8.9 3.9 3.5 7.4 0.2 2.0 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Rubredoxin PF00301.15 AIF83576.1 - 1.3 8.9 4.3 9.7 6.1 0.4 2.2 2 0 0 2 2 2 0 Rubredoxin zf-MYND PF01753.13 AIF83576.1 - 1.3 8.9 5.3 7.2 6.5 3.7 1.9 1 1 0 1 1 1 0 MYND finger zf-HIT PF04438.11 AIF83576.1 - 1.5 8.5 5.7 4.6 6.9 0.6 2.1 2 0 0 2 2 2 0 HIT zinc finger TFIIS_C PF01096.13 AIF83576.1 - 1.6 8.4 7.8 4.2 7.0 0.5 2.1 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_4 PF13894.1 AIF83576.1 - 1.7 9.1 4.1 29 5.3 0.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIF83576.1 - 3.7 7.5 6.2 1.4 8.9 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger MIase PF02426.11 AIF83580.1 - 3e-07 30.1 0.0 5.8e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Muconolactone delta-isomerase YCII PF03795.9 AIF83580.1 - 0.046 13.9 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 YCII-related domain Aldo_ket_red PF00248.16 AIF83580.1 - 0.083 11.7 0.0 4.1 6.1 0.0 2.0 1 1 1 2 2 2 0 Aldo/keto reductase family Hemerythrin PF01814.18 AIF83581.1 - 1.8e-12 47.5 0.1 3.9e-12 46.4 0.1 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain GFA PF04828.9 AIF83582.1 - 0.0099 15.8 0.0 2.1 8.3 0.0 2.1 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.9 AIF83582.1 - 0.017 15.1 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4451 PF14616.1 AIF83582.1 - 0.11 12.2 0.2 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) Rpr2 PF04032.11 AIF83582.1 - 0.11 12.3 0.0 8.7 6.3 0.0 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1843 PF08898.5 AIF83582.1 - 0.14 12.2 0.3 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Arc_trans_TRASH PF08394.5 AIF83582.1 - 0.24 11.5 1.6 2.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Archaeal TRASH domain PDZ_2 PF13180.1 AIF83583.1 - 9.6e-16 57.4 1.2 1.7e-07 31.0 0.1 2.2 1 1 1 2 2 2 2 PDZ domain PDZ PF00595.19 AIF83583.1 - 9.5e-10 38.5 1.0 6.7e-05 22.9 0.1 2.2 1 1 1 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 AIF83583.1 - 0.00027 20.6 0.3 0.025 14.3 0.0 2.4 1 1 1 2 2 2 2 Tricorn protease PDZ domain GRASP55_65 PF04495.9 AIF83583.1 - 0.031 14.2 0.1 0.13 12.2 0.0 1.9 1 1 1 2 2 2 0 GRASP55/65 PDZ-like domain Aminotran_3 PF00202.16 AIF83584.1 - 1.6e-75 254.0 0.0 2e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 AIF83584.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PrpR_N PF06506.6 AIF83584.1 - 0.088 12.2 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Propionate catabolism activator Acyl-CoA_dh_1 PF00441.19 AIF83585.1 - 3.9e-33 114.6 4.2 3.6e-18 66.1 0.7 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AIF83585.1 - 3.2e-20 72.7 0.5 9.8e-20 71.2 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AIF83585.1 - 6.2e-16 57.6 0.3 1.6e-15 56.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AIF83585.1 - 4.3e-10 39.9 9.3 3e-09 37.2 6.4 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HATPase_c_3 PF13589.1 AIF83585.1 - 0.093 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MaoC_dehydratas PF01575.14 AIF83586.1 - 1.4e-05 24.4 0.0 0.00017 20.9 0.0 2.0 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 AIF83586.1 - 0.019 14.7 0.1 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase DUF4423 PF14394.1 AIF83588.1 - 0.00095 18.7 0.3 0.017 14.6 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4423) HTH_45 PF14947.1 AIF83588.1 - 0.017 14.9 0.1 0.039 13.7 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix PLDc_2 PF13091.1 AIF83589.1 - 0.064 13.0 0.2 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 PLD-like domain UbiA PF01040.13 AIF83590.1 - 1.4e-30 106.4 15.7 1.8e-30 106.0 10.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family HTH_45 PF14947.1 AIF83591.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix UbiA PF01040.13 AIF83592.1 - 5.4e-32 111.0 14.3 7.4e-32 110.5 9.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MmgE_PrpD PF03972.9 AIF83593.1 - 1.3e-28 99.3 0.1 4.5e-28 97.6 0.1 1.7 1 1 0 1 1 1 1 MmgE/PrpD family Cupin_2 PF07883.6 AIF83594.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Pectate_lyase_3 PF12708.2 AIF83594.1 - 0.016 15.2 0.1 0.03 14.4 0.1 1.4 1 1 1 2 2 2 0 Pectate lyase superfamily protein AraC_binding PF02311.14 AIF83594.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain MannoseP_isomer PF01050.13 AIF83594.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Mannose-6-phosphate isomerase DZR PF12773.2 AIF83595.1 - 0.0017 18.1 1.8 0.0023 17.7 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon DNA_ligase_ZBD PF03119.11 AIF83595.1 - 0.0032 17.1 2.5 0.73 9.5 0.1 2.3 2 0 0 2 2 2 2 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.1 AIF83595.1 - 0.0098 15.0 6.6 0.14 11.4 0.7 2.2 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF83595.1 - 0.015 14.8 6.5 0.74 9.3 3.8 2.2 1 1 2 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.6 AIF83595.1 - 0.019 14.7 1.5 0.029 14.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.7 AIF83595.1 - 0.027 14.2 0.5 0.039 13.7 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_3 PF13920.1 AIF83595.1 - 0.098 12.3 1.9 0.14 11.8 1.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIF83595.1 - 0.12 12.1 3.9 0.17 11.6 2.7 1.2 1 0 0 1 1 1 0 zinc-RING finger domain SieB PF14163.1 AIF83595.1 - 0.14 11.7 0.4 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B zf-NADH-PPase PF09297.6 AIF83595.1 - 0.15 11.5 4.4 1.3 8.5 0.5 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PolC_DP2 PF03833.8 AIF83595.1 - 0.17 9.5 0.4 0.2 9.2 0.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ISL3 PF14690.1 AIF83595.1 - 0.24 11.4 5.5 0.32 11.0 0.4 2.4 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF1610 PF07754.6 AIF83595.1 - 0.26 11.4 9.0 2.5 8.2 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Sgf11 PF08209.6 AIF83595.1 - 0.26 10.6 0.2 0.26 10.6 0.2 2.1 1 1 1 2 2 2 0 Sgf11 (transcriptional regulation protein) Prim_Zn_Ribbon PF08273.7 AIF83595.1 - 0.28 11.3 9.8 1.9 8.6 1.0 2.6 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase zinc_ribbon_5 PF13719.1 AIF83595.1 - 0.37 10.4 4.0 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 AIF83595.1 - 0.37 10.4 4.5 0.58 9.8 3.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 AIF83595.1 - 0.49 10.4 5.6 5.5 7.0 3.9 2.1 1 1 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AIF83595.1 - 0.51 10.0 4.2 5.9 6.6 0.3 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.1 AIF83595.1 - 0.56 9.9 4.2 1.9 8.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AIF83595.1 - 0.58 9.5 7.0 4.7 6.6 4.8 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zf-HIT PF04438.11 AIF83595.1 - 0.63 9.7 5.5 0.98 9.1 3.8 1.3 1 0 0 1 1 1 0 HIT zinc finger TFIIS_C PF01096.13 AIF83595.1 - 1.1 8.8 4.5 15 5.3 0.3 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) RRN7 PF11781.3 AIF83595.1 - 6.3 6.3 6.9 3.4 7.2 1.1 2.3 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HYPF PF07503.7 AIF83595.1 - 7.4 6.0 8.0 1.5 8.2 0.6 2.9 2 1 1 3 3 3 0 HypF finger C1_4 PF07975.7 AIF83596.1 - 0.0038 17.2 0.5 0.0038 17.2 0.4 1.1 1 0 0 1 1 1 1 TFIIH C1-like domain zf-met PF12874.2 AIF83596.1 - 0.034 14.3 0.6 0.061 13.5 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AIF83596.1 - 0.16 12.1 0.7 0.23 11.6 0.5 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding IMS PF00817.15 AIF83597.1 - 2.3e-42 144.3 0.2 5.7e-42 143.0 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family DUF72 PF01904.13 AIF83597.1 - 1.1e-18 67.8 0.0 2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF72 IMS_C PF11799.3 AIF83597.1 - 5.2e-16 58.7 0.0 9.3e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AIF83597.1 - 2.5e-07 30.3 0.1 5.4e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 AIF83597.1 - 0.00024 21.2 0.0 0.00062 19.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 AIF83597.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 Pathogenicity locus DUF4332 PF14229.1 AIF83597.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Fer4_8 PF13183.1 AIF83598.1 - 0.02 14.8 1.6 0.02 14.8 1.1 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Carla_C4 PF01623.12 AIF83598.1 - 0.1 12.3 4.6 0.11 12.2 3.2 1.1 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Tnp_zf-ribbon_2 PF13842.1 AIF83598.1 - 0.71 10.3 12.6 3.6 8.0 8.8 1.9 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Pro_isomerase PF00160.16 AIF83599.1 - 1.4e-51 174.8 0.2 1.6e-51 174.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TetR_N PF00440.18 AIF83600.1 - 2.8e-18 65.2 0.0 5.3e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.1 AIF83600.1 - 9.8e-12 44.9 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional repressor RVT_3 PF13456.1 AIF83601.1 - 6e-19 67.6 0.1 7.9e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 AIF83601.1 - 5.1e-12 46.2 0.0 6.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 RNase H TrbC PF04956.8 AIF83602.1 - 1.9 8.5 5.1 10 6.2 3.0 2.0 1 1 1 2 2 2 0 TrbC/VIRB2 family Cupin_2 PF07883.6 AIF83603.1 - 3.7e-20 71.1 0.0 5.6e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AIF83603.1 - 7.7e-06 25.6 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Auxin_BP PF02041.11 AIF83603.1 - 5.1e-05 22.7 0.0 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 Auxin binding protein Cupin_1 PF00190.17 AIF83603.1 - 7.3e-05 22.2 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 AIF83603.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 AIF83603.1 - 0.0092 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ CENP-C_C PF11699.3 AIF83603.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like MannoseP_isomer PF01050.13 AIF83603.1 - 0.03 13.9 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CCDC155 PF14662.1 AIF83604.1 - 0.00097 18.7 0.5 0.00098 18.7 0.4 1.0 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Bap31 PF05529.7 AIF83604.1 - 0.006 16.0 0.3 0.0064 15.9 0.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Seryl_tRNA_N PF02403.17 AIF83604.1 - 0.0082 16.1 0.5 0.0089 16.0 0.4 1.0 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.1 AIF83604.1 - 0.0089 15.4 2.6 0.01 15.2 1.8 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.1 AIF83604.1 - 0.013 14.6 1.3 0.014 14.5 0.9 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.1 AIF83604.1 - 0.015 15.2 0.5 0.016 15.1 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4200 PF13863.1 AIF83604.1 - 0.016 15.1 0.5 0.018 14.9 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 AIF83604.1 - 0.032 14.0 3.1 0.038 13.8 2.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1811 PF08838.5 AIF83604.1 - 0.037 13.9 0.3 0.04 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) DUF4319 PF14203.1 AIF83604.1 - 0.045 13.3 0.1 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) DUF4140 PF13600.1 AIF83604.1 - 0.057 13.8 0.3 0.059 13.8 0.2 1.0 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 AIF83604.1 - 0.059 12.8 0.6 0.066 12.7 0.4 1.1 1 0 0 1 1 1 0 Septum formation initiator Med9 PF07544.8 AIF83604.1 - 0.09 12.5 0.6 0.11 12.2 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Macoilin PF09726.4 AIF83604.1 - 0.1 10.8 0.7 0.1 10.8 0.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF465 PF04325.8 AIF83604.1 - 4.3 7.1 8.3 7.3 6.3 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF465) SIMPL PF04402.9 AIF83605.1 - 5.5e-44 150.5 4.4 7.3e-44 150.1 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF3597 PF12200.3 AIF83605.1 - 4.7 7.6 7.3 0.63 10.4 1.5 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3597) Beta_propel PF09826.4 AIF83606.1 - 1.4e-152 508.6 8.1 1.8e-152 508.3 5.6 1.0 1 0 0 1 1 1 1 Beta propeller domain Ald_Xan_dh_C2 PF02738.13 AIF83607.1 - 0.086 11.1 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase SR-25 PF10500.4 AIF83607.1 - 0.22 10.9 3.0 0.32 10.4 2.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ODV-E18 PF10717.4 AIF83607.1 - 3.5 7.1 10.9 1.2 8.5 0.7 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Gp58 PF07902.6 AIF83608.1 - 0.024 12.8 1.4 0.028 12.6 1.0 1.2 1 0 0 1 1 1 0 gp58-like protein Peptidase_M13_N PF05649.8 AIF83608.1 - 0.031 13.3 2.8 0.039 13.0 2.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 IncA PF04156.9 AIF83608.1 - 0.12 11.9 6.9 0.15 11.6 4.8 1.2 1 0 0 1 1 1 0 IncA protein CorA PF01544.13 AIF83608.1 - 0.12 11.3 0.2 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.7 AIF83608.1 - 0.13 11.9 12.6 0.056 13.1 2.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2951 PF11166.3 AIF83608.1 - 0.16 11.8 4.6 0.26 11.1 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) BLOC1_2 PF10046.4 AIF83608.1 - 0.21 11.7 6.4 0.2 11.8 1.9 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3138 PF11336.3 AIF83608.1 - 0.38 8.8 4.5 0.51 8.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CDC37_N PF03234.9 AIF83608.1 - 0.47 10.7 7.6 0.71 10.1 5.3 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Spc7 PF08317.6 AIF83608.1 - 0.5 8.9 8.4 0.62 8.6 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein XkdW PF09636.5 AIF83608.1 - 0.53 10.1 5.8 0.47 10.3 1.2 2.2 1 1 1 2 2 2 0 XkdW protein Shugoshin_N PF07558.6 AIF83608.1 - 0.94 9.2 5.9 0.15 11.8 1.2 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region YjcZ PF13990.1 AIF83608.1 - 0.96 8.5 6.2 1.4 7.9 4.3 1.3 1 1 0 1 1 1 0 YjcZ-like protein APG6 PF04111.7 AIF83608.1 - 1.1 8.2 10.4 0.074 12.0 3.3 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3508 PF12018.3 AIF83608.1 - 1.6 7.6 7.2 4.9 6.0 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Birna_RdRp PF04197.7 AIF83608.1 - 2.2 6.1 10.8 2.4 6.0 7.5 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) ATG16 PF08614.6 AIF83608.1 - 3.1 7.5 13.8 0.1 12.3 2.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AATF-Che1 PF13339.1 AIF83608.1 - 3.9 7.6 12.9 1.1 9.3 5.8 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor CP12 PF02672.10 AIF83608.1 - 5.3 7.5 7.8 3.2 8.2 0.1 2.5 2 1 1 3 3 3 0 CP12 domain bZIP_1 PF00170.16 AIF83608.1 - 5.6 6.9 15.1 0.5 10.3 0.3 3.3 1 1 2 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 AIF83608.1 - 5.7 7.3 11.7 2.9 8.2 3.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FlxA PF14282.1 AIF83608.1 - 6.8 6.6 20.0 0.11 12.4 5.8 2.3 1 1 1 2 2 2 0 FlxA-like protein Muted PF14942.1 AIF83608.1 - 7.4 6.4 9.3 1.6 8.5 3.0 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Copper-bind PF00127.15 AIF83609.1 - 1.5e-06 28.3 0.2 0.021 15.0 0.0 2.7 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF83609.1 - 0.0065 16.3 0.4 0.27 11.1 0.0 2.5 2 1 0 2 2 2 1 Cupredoxin-like domain MacB_PCD PF12704.2 AIF83609.1 - 0.033 13.7 0.3 0.047 13.2 0.2 1.2 1 0 0 1 1 1 0 MacB-like periplasmic core domain A2L_zn_ribbon PF08792.5 AIF83610.1 - 0.0077 15.6 2.3 0.28 10.7 0.1 2.1 2 0 0 2 2 2 2 A2L zinc ribbon domain DUF1451 PF07295.6 AIF83610.1 - 0.011 15.4 0.3 0.012 15.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) zf-ribbon_3 PF13248.1 AIF83610.1 - 0.23 10.7 1.5 1.5 8.0 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L32p PF01783.18 AIF83611.1 - 0.011 15.8 6.9 0.012 15.7 0.8 2.1 1 1 1 2 2 2 0 Ribosomal L32p protein family DZR PF12773.2 AIF83611.1 - 0.016 15.0 7.6 0.18 11.6 5.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF3133 PF11331.3 AIF83611.1 - 0.19 11.3 2.1 0.29 10.7 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) Ribosomal_L40e PF01020.12 AIF83611.1 - 0.94 9.1 4.8 0.41 10.2 1.9 1.5 1 1 0 1 1 1 0 Ribosomal L40e family zf-ribbon_3 PF13248.1 AIF83611.1 - 1.1 8.5 7.7 4 6.7 2.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 AIF83611.1 - 1.1 8.8 8.1 0.46 10.0 3.4 2.1 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Rpr2 PF04032.11 AIF83611.1 - 1.4 8.8 4.7 4.5 7.2 3.2 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF35_N PF12172.3 AIF83611.1 - 2.6 8.0 10.7 0.23 11.4 2.2 2.3 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) LOH1CR12 PF10158.4 AIF83612.1 - 0.016 14.9 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor protein HypA PF01155.14 AIF83613.1 - 0.031 13.9 0.2 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 AIF83613.1 - 0.041 13.9 0.5 0.053 13.5 0.4 1.1 1 0 0 1 1 1 0 Stc1 domain zinc_ribbon_5 PF13719.1 AIF83613.1 - 0.047 13.2 0.8 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Adeno_E3_15_3 PF03307.9 AIF83613.1 - 0.075 12.7 0.1 0.087 12.5 0.1 1.2 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region zinc_ribbon_4 PF13717.1 AIF83613.1 - 0.12 12.1 0.8 0.7 9.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF4213 PF13938.1 AIF83613.1 - 0.12 12.4 0.1 0.24 11.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) TFIIS_C PF01096.13 AIF83613.1 - 3.4 7.3 5.9 40 3.9 4.1 2.4 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) FlgD_ig PF13860.1 AIF83614.1 - 2e-12 46.6 1.4 2e-12 46.6 0.9 2.1 2 0 0 2 2 2 1 FlgD Ig-like domain CHU_C PF13585.1 AIF83614.1 - 0.00039 20.2 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of CHU protein family DUF2271 PF10029.4 AIF83614.1 - 0.006 16.0 0.2 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 Predicted periplasmic protein (DUF2271) DUF3244 PF11589.3 AIF83614.1 - 0.13 11.9 0.4 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) N6_N4_Mtase PF01555.13 AIF83615.1 - 1.9e-41 142.0 0.0 2.7e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 AIF83615.1 - 2.3e-12 46.9 0.0 6.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.13 AIF83615.1 - 4.5e-05 23.0 0.0 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 AIF83615.1 - 4.5e-05 23.9 0.0 0.00028 21.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF83615.1 - 0.00021 20.9 0.0 0.0028 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83615.1 - 0.004 17.6 0.1 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 AIF83615.1 - 0.015 14.8 0.0 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.7 AIF83615.1 - 0.024 15.1 0.0 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 AIF83615.1 - 0.088 13.1 0.1 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Profilin PF00235.14 AIF83617.1 - 0.085 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Profilin CHASE4 PF05228.8 AIF83617.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 CHASE4 domain YjeF_N PF03853.10 AIF83618.1 - 1.9e-46 157.7 0.2 2.3e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Lactamase_B PF00753.22 AIF83619.1 - 3.9e-25 88.6 0.4 4.6e-25 88.3 0.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIF83619.1 - 3.2e-05 23.5 0.1 6.1e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF4261 PF14080.1 AIF83619.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) CBS PF00571.23 AIF83619.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 CBS domain DBI_PRT PF02277.12 AIF83620.1 - 1.4e-32 113.1 5.4 2.4e-32 112.3 3.8 1.3 1 0 0 1 1 1 1 Phosphoribosyltransferase DUF4292 PF14125.1 AIF83621.1 - 0.0004 19.8 0.2 0.0034 16.8 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4292) Pur_DNA_glyco PF02245.11 AIF83622.1 - 4.9e-63 211.6 0.0 5.5e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) UDG PF03167.14 AIF83623.1 - 6.7e-42 142.5 0.0 8.7e-42 142.1 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Gram_pos_anchor PF00746.16 AIF83624.1 - 0.13 12.0 7.5 2.8 7.8 1.5 2.1 2 0 0 2 2 2 0 Gram positive anchor DUF202 PF02656.10 AIF83624.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF3185 PF11381.3 AIF83624.1 - 0.28 10.9 3.1 6.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Transglut_core2 PF13369.1 AIF83625.1 - 3.5e-39 133.7 0.0 5.5e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.1 AIF83625.1 - 6.1e-11 42.0 0.1 1.2e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 AIF83625.1 - 0.061 12.9 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 AIF83625.1 - 0.065 13.9 0.7 0.18 12.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AIF83625.1 - 0.14 12.8 0.3 0.14 12.8 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Ammonium_transp PF00909.16 AIF83626.1 - 2.4e-117 391.7 33.9 3.6e-117 391.2 23.5 1.3 1 0 0 1 1 1 1 Ammonium Transporter Family Na_H_Exchanger PF00999.16 AIF83628.1 - 2.8e-65 220.3 59.9 3.7e-65 219.9 41.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Frankia_peptide PF14407.1 AIF83629.1 - 0.0011 18.6 0.0 0.0014 18.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. LigA PF07746.6 AIF83629.1 - 0.03 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit OGG_N PF07934.7 AIF83630.1 - 1.6e-15 57.0 0.0 3.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 AIF83630.1 - 3e-12 46.7 0.0 4.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AIF83630.1 - 0.00077 19.0 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 AIF83630.1 - 0.0024 17.7 0.0 0.3 11.0 0.0 3.3 4 0 0 4 4 4 1 Helix-hairpin-helix motif HHH_3 PF12836.2 AIF83630.1 - 0.079 12.9 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif DZR PF12773.2 AIF83632.1 - 0.0051 16.5 1.4 0.0061 16.3 1.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon DNA_RNApol_7kD PF03604.8 AIF83632.1 - 0.011 15.2 5.4 0.021 14.3 3.8 1.6 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L40e PF01020.12 AIF83632.1 - 0.024 14.2 5.9 0.029 13.9 4.1 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Prok-RING_1 PF14446.1 AIF83632.1 - 0.044 13.5 1.8 0.058 13.1 1.2 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 NT5C PF06941.7 AIF83632.1 - 0.063 12.7 0.1 0.066 12.7 0.1 1.1 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) zf-CCHC PF00098.18 AIF83632.1 - 0.086 12.8 0.8 0.086 12.8 0.6 2.4 2 1 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.1 AIF83632.1 - 0.14 11.4 1.5 0.21 10.8 1.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Mu-like_Com PF10122.4 AIF83632.1 - 0.18 10.8 8.2 6.8 5.8 5.7 2.2 1 1 0 1 1 1 0 Mu-like prophage protein Com Paired_CXXCH_1 PF09699.5 AIF83632.1 - 0.28 10.7 6.9 0.37 10.3 1.7 2.1 1 1 1 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zinc_ribbon_2 PF13240.1 AIF83632.1 - 0.39 10.2 2.9 0.76 9.3 2.0 1.5 1 1 0 1 1 1 0 zinc-ribbon domain Fer4_4 PF12800.2 AIF83632.1 - 0.6 10.5 2.7 19 5.8 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Zn_Tnp_IS1595 PF12760.2 AIF83632.1 - 1 9.1 7.1 38 4.1 4.9 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Antitoxin-MazE PF04014.13 AIF83633.1 - 0.051 13.3 0.4 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Abhydrolase_6 PF12697.2 AIF83634.1 - 2.7e-40 138.6 0.0 3.1e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIF83634.1 - 2.5e-28 99.2 0.0 3.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIF83634.1 - 3.1e-18 65.9 0.0 6.6e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AIF83634.1 - 0.00015 21.4 0.0 0.00039 20.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 AIF83634.1 - 0.0033 17.0 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.9 AIF83634.1 - 0.013 13.9 0.0 0.038 12.4 0.0 1.6 1 1 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.11 AIF83634.1 - 0.015 14.7 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 AIF83634.1 - 0.018 14.7 0.0 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.3 AIF83634.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 AIF83634.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein Ribosomal_L1 PF00687.16 AIF83635.1 - 0.027 13.8 0.5 0.029 13.7 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family HTH_45 PF14947.1 AIF83636.1 - 1.7e-19 69.4 0.1 2.4e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF83636.1 - 0.0041 16.7 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) APC2 PF08672.6 AIF83636.1 - 0.065 13.4 0.1 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Mrr_N PF14338.1 AIF83636.1 - 0.13 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain zf-ribbon_3 PF13248.1 AIF83637.1 - 0.0063 15.6 0.8 1.5 8.1 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIF83637.1 - 0.017 14.7 0.5 0.028 14.0 0.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.7 AIF83637.1 - 0.041 13.9 4.2 0.098 12.7 2.9 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF2318 PF10080.4 AIF83637.1 - 0.049 13.3 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-CCHC_2 PF13696.1 AIF83637.1 - 0.071 12.6 1.3 0.075 12.5 0.1 1.6 2 0 0 2 2 2 0 Zinc knuckle DUF4167 PF13763.1 AIF83637.1 - 0.098 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) PhnA_Zn_Ribbon PF08274.7 AIF83637.1 - 0.16 11.7 0.9 0.41 10.4 0.6 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon RRN7 PF11781.3 AIF83637.1 - 0.18 11.3 10.7 0.089 12.3 5.3 2.0 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1595 PF12760.2 AIF83637.1 - 0.44 10.3 5.3 1.8 8.4 3.9 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF83637.1 - 0.8 9.2 3.0 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 AIF83637.1 - 2.7 8.3 6.5 5.6 7.3 4.5 1.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF2848 PF11010.3 AIF83638.1 - 0.047 13.1 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) Copper-bind PF00127.15 AIF83639.1 - 3.5e-11 43.2 0.1 4.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF83639.1 - 3.1e-05 23.8 0.0 6.7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Cupredoxin-like domain Cytochrom_B_N_2 PF13631.1 AIF83640.1 - 2.6e-24 85.8 11.1 2.6e-24 85.8 7.7 3.8 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 AIF83640.1 - 2.4e-08 34.0 1.0 2.4e-08 34.0 0.7 3.9 3 1 2 5 5 5 1 Cytochrome b(C-terminal)/b6/petD DUF1469 PF07332.6 AIF83640.1 - 0.052 13.2 0.3 0.052 13.2 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) SseB PF07179.7 AIF83640.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 SseB protein N-terminal domain CAMSAP_CH PF11971.3 AIF83640.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain UPF0542 PF15086.1 AIF83640.1 - 0.4 10.4 0.1 0.4 10.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Adeno_E3_14_5 PF04834.7 AIF83640.1 - 7.8 6.9 12.9 4.7 7.7 1.8 3.9 2 1 2 4 4 4 0 Early E3 14.5 kDa protein Rieske PF00355.21 AIF83641.1 - 6.9e-09 35.1 0.0 1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.4 AIF83641.1 - 0.00051 19.8 0.2 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.4 AIF83641.1 - 0.0025 16.9 0.2 0.0049 16.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pentapeptide PF00805.17 AIF83642.1 - 1.1e-31 107.5 27.0 1.2e-09 37.2 1.5 4.7 2 1 4 6 6 6 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 AIF83642.1 - 2.3e-14 52.9 0.5 5.4e-09 35.7 0.5 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 AIF83642.1 - 1.1e-09 38.0 0.1 9.2e-05 22.2 0.1 3.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) TP_methylase PF00590.15 AIF83643.1 - 7.3e-21 74.8 0.5 6e-20 71.8 0.0 2.0 1 1 1 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.8 AIF83643.1 - 1.1e-10 41.0 0.7 3.4e-10 39.4 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF357) HEPN PF05168.9 AIF83643.1 - 0.085 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 HEPN domain Peptidase_M20 PF01546.23 AIF83644.1 - 1e-28 100.1 0.0 1.6e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AIF83644.1 - 1.2e-13 50.7 0.0 2.3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 AIF83644.1 - 0.00032 19.5 0.2 0.22 10.2 0.0 2.9 3 1 1 4 4 4 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 AIF83644.1 - 0.0022 17.7 0.1 0.0067 16.1 0.0 2.0 3 0 0 3 3 3 1 Peptidase family M28 RimK PF08443.6 AIF83645.1 - 9.7e-48 162.1 0.0 2.1e-47 161.0 0.0 1.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 AIF83645.1 - 1.8e-09 37.5 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.11 AIF83645.1 - 8.3e-09 34.8 0.0 1.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.9 AIF83645.1 - 3.7e-07 30.1 0.0 6.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AIF83645.1 - 7.6e-07 28.6 0.1 3.5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 AIF83645.1 - 1.7e-05 23.7 0.0 0.00023 20.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AIF83645.1 - 0.00015 21.2 0.0 0.00042 19.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 AIF83645.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain zinc_ribbon_5 PF13719.1 AIF83646.1 - 3e-06 26.7 2.5 0.0015 18.1 2.4 2.3 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIF83646.1 - 8.9e-06 25.3 2.4 0.061 13.0 0.0 2.2 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF83646.1 - 0.00012 21.1 0.7 0.08 12.1 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-HYPF PF07503.7 AIF83646.1 - 0.00015 21.0 1.6 0.0015 17.8 1.1 2.0 1 1 0 1 1 1 1 HypF finger Prok-RING_1 PF14446.1 AIF83646.1 - 0.00027 20.5 3.0 0.001 18.7 2.1 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.7 AIF83646.1 - 0.0004 20.1 0.6 0.25 11.1 0.0 2.1 2 0 0 2 2 2 2 PhnA Zinc-Ribbon UPF0547 PF10571.4 AIF83646.1 - 0.00085 18.9 5.1 0.029 14.0 0.3 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 AIF83646.1 - 0.0012 18.2 1.4 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-IS66 PF13005.2 AIF83646.1 - 0.0013 18.6 0.9 0.095 12.6 0.1 2.3 2 1 0 2 2 2 1 zinc-finger binding domain of transposase IS66 TerY-C PF15616.1 AIF83646.1 - 0.0018 18.2 0.4 0.027 14.4 0.3 2.0 1 1 0 1 1 1 1 TerY-C metal binding domain zf-TFIIB PF13453.1 AIF83646.1 - 0.0053 15.9 0.3 0.0068 15.5 0.2 1.4 1 0 0 1 1 1 1 Transcription factor zinc-finger DNA_ligase_ZBD PF03119.11 AIF83646.1 - 0.0054 16.3 3.4 0.59 9.8 0.5 2.4 2 1 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain zf-C4_Topoisom PF01396.14 AIF83646.1 - 0.0063 15.9 1.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger A2L_zn_ribbon PF08792.5 AIF83646.1 - 0.008 15.6 1.9 0.11 11.9 0.1 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 AIF83646.1 - 0.0095 15.2 2.1 0.016 14.5 1.5 1.4 1 1 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 AIF83646.1 - 0.01 15.4 0.2 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.2 AIF83646.1 - 0.01 15.6 0.9 0.019 14.7 0.6 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-CSL PF05207.8 AIF83646.1 - 0.022 14.2 0.6 0.03 13.8 0.4 1.3 1 0 0 1 1 1 0 CSL zinc finger zinc-ribbons_6 PF07191.7 AIF83646.1 - 0.022 14.5 1.4 0.13 12.0 1.0 1.9 1 1 0 1 1 1 0 zinc-ribbons ADK_lid PF05191.9 AIF83646.1 - 0.031 13.9 0.7 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid Lar_restr_allev PF14354.1 AIF83646.1 - 0.031 14.5 2.2 0.14 12.4 1.5 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_3 PF14369.1 AIF83646.1 - 0.032 14.2 2.9 0.088 12.8 2.0 1.7 1 1 0 1 1 1 0 zinc-finger Rubredoxin PF00301.15 AIF83646.1 - 0.036 13.9 1.4 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Rubredoxin CpXC PF14353.1 AIF83646.1 - 0.038 13.9 1.2 4.1 7.3 0.1 2.1 1 1 1 2 2 2 0 CpXC protein DNA_RNApol_7kD PF03604.8 AIF83646.1 - 0.038 13.4 3.0 0.12 11.8 2.1 1.8 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 AIF83646.1 - 0.039 13.9 3.6 0.22 11.4 2.5 1.9 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 AIF83646.1 - 0.046 13.4 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF329 PF03884.9 AIF83646.1 - 0.061 12.8 2.9 3.7 7.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF329) COX5B PF01215.14 AIF83646.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase subunit Vb Cys_rich_CPXG PF14255.1 AIF83646.1 - 0.083 12.7 0.9 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG Zn_Tnp_IS1 PF03811.8 AIF83646.1 - 0.11 11.9 1.1 6.9 6.2 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain zf-H2C2_2 PF13465.1 AIF83646.1 - 0.12 12.7 0.7 7.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Sgf11 PF08209.6 AIF83646.1 - 0.13 11.6 1.3 5.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF164 PF02591.10 AIF83646.1 - 0.15 11.9 4.6 0.45 10.3 0.1 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 AIF83646.1 - 0.17 11.6 2.5 1.4 8.7 0.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.5 AIF83646.1 - 0.35 10.8 1.9 0.48 10.3 1.3 1.3 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Ogr_Delta PF04606.7 AIF83646.1 - 0.39 10.3 2.1 14 5.4 0.2 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_S27e PF01667.12 AIF83646.1 - 0.48 10.0 2.1 1.7 8.2 1.4 1.8 1 1 0 1 1 1 0 Ribosomal protein S27 DUF3797 PF12677.2 AIF83646.1 - 0.66 9.6 3.2 2.5 7.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) HMGL-like PF00682.14 AIF83647.1 - 1.1e-64 218.3 0.5 1.5e-64 217.8 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Lyase_1 PF00206.15 AIF83648.1 - 1.2e-55 188.9 0.0 2e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 AIF83648.1 - 2.5e-14 53.1 0.4 9.3e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Nepo_coat PF03391.10 AIF83649.1 - 0.13 11.5 0.7 0.15 11.3 0.5 1.1 1 0 0 1 1 1 0 Nepovirus coat protein, central domain DUF59 PF01883.14 AIF83651.1 - 3.7e-13 49.2 0.0 5.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF59 BNR PF02012.15 AIF83653.1 - 1.5e-05 24.1 1.5 7.1 6.9 0.0 4.8 4 0 0 4 4 4 2 BNR/Asp-box repeat BNR_2 PF13088.1 AIF83653.1 - 0.00081 18.7 0.0 5.3 6.2 0.0 3.5 2 1 1 3 3 3 2 BNR repeat-like domain BNR_3 PF13859.1 AIF83653.1 - 0.12 11.4 0.0 0.41 9.6 0.0 1.8 2 0 0 2 2 2 0 BNR repeat-like domain Fer2_3 PF13085.1 AIF83654.1 - 1.6e-28 98.6 0.1 5.1e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 AIF83654.1 - 4.5e-11 42.6 4.0 1.4e-10 41.0 1.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AIF83654.1 - 1.9e-10 40.9 5.7 1e-08 35.4 0.3 2.8 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AIF83654.1 - 1.5e-09 38.0 3.0 1.6e-09 37.9 0.3 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF83654.1 - 2.1e-07 30.6 1.4 2.1e-07 30.6 0.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 AIF83654.1 - 3.2e-07 30.6 2.8 3.2e-07 30.6 1.9 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 AIF83654.1 - 1.1e-06 28.2 0.1 3.4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 AIF83654.1 - 3.2e-06 27.3 4.8 6.1e-06 26.4 1.5 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.22 AIF83654.1 - 1.2e-05 24.7 1.0 1.2e-05 24.7 0.7 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.2 AIF83654.1 - 0.00036 20.2 0.8 0.00036 20.2 0.5 3.3 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_16 PF13484.1 AIF83654.1 - 0.00044 20.9 3.0 0.00044 20.9 2.1 2.3 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.2 AIF83654.1 - 0.0023 17.7 2.3 0.0023 17.7 1.6 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_4 PF12800.2 AIF83654.1 - 0.0063 16.7 1.9 0.0063 16.7 1.3 3.2 3 0 0 3 3 3 1 4Fe-4S binding domain Fer2_4 PF13510.1 AIF83654.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer4_3 PF12798.2 AIF83654.1 - 2.8 8.7 22.7 0.33 11.6 0.5 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 AIF83654.1 - 3.8 8.1 8.0 0.82 10.2 0.1 2.8 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_21 PF14697.1 AIF83654.1 - 8.5 6.3 15.8 1 9.2 6.0 2.6 2 1 0 2 2 1 0 4Fe-4S dicluster domain Sdh_cyt PF01127.17 AIF83655.1 - 9.1e-09 35.1 6.5 1.2e-08 34.8 4.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.14 AIF83655.1 - 0.1 12.6 7.5 0.18 11.9 5.2 1.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF1129 PF06570.6 AIF83655.1 - 0.11 11.7 5.5 0.019 14.2 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) TRP PF06011.7 AIF83655.1 - 0.16 10.5 4.7 0.19 10.2 3.2 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF1691 PF07950.6 AIF83655.1 - 0.27 11.1 6.2 0.29 11.0 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1691) Arif-1 PF06770.6 AIF83655.1 - 0.38 10.1 7.3 0.45 9.8 5.1 1.0 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Sdh_cyt PF01127.17 AIF83656.1 - 4.9e-13 48.9 0.2 6.2e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.14 AIF83656.1 - 0.0082 16.2 0.1 0.025 14.6 0.1 1.7 1 1 0 1 1 1 1 Ferric reductase like transmembrane component Fumarate_red_C PF02300.12 AIF83656.1 - 0.021 14.6 0.5 0.037 13.9 0.0 1.5 2 0 0 2 2 2 0 Fumarate reductase subunit C FAD_binding_2 PF00890.19 AIF83657.1 - 2.4e-95 319.8 0.2 3.2e-95 319.4 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AIF83657.1 - 7.5e-40 135.7 0.6 1.3e-39 135.0 0.4 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 AIF83657.1 - 3.6e-05 23.7 2.1 0.00076 19.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AIF83657.1 - 0.0039 16.3 0.6 0.096 11.7 0.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 AIF83657.1 - 0.011 14.6 0.2 0.03 13.2 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 AIF83657.1 - 0.039 12.8 0.4 0.039 12.8 0.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 AIF83657.1 - 0.044 12.7 0.4 0.067 12.0 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MTH865 PF07747.6 AIF83657.1 - 0.12 12.0 0.0 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 MTH865-like family HI0933_like PF03486.9 AIF83657.1 - 0.13 10.7 0.6 0.26 9.6 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 AIF83657.1 - 0.22 10.5 2.4 0.71 8.9 0.4 2.3 2 0 0 2 2 2 0 Thi4 family DNA_pol_alpha_N PF12254.3 AIF83657.1 - 0.49 10.2 3.7 9.5 6.1 0.1 2.9 3 0 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal Ribosomal_L24e PF01246.15 AIF83660.1 - 4.3e-17 61.7 0.8 5e-17 61.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L24e DUF2116 PF09889.4 AIF83660.1 - 0.0018 18.0 0.9 0.86 9.4 0.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein containing a Zn-ribbon (DUF2116) A2L_zn_ribbon PF08792.5 AIF83660.1 - 0.0026 17.1 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 AIF83660.1 - 0.055 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Arc_trans_TRASH PF08394.5 AIF83660.1 - 0.074 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Archaeal TRASH domain PIN PF01850.16 AIF83664.1 - 5.6e-12 46.0 0.5 6.2e-12 45.9 0.3 1.0 1 0 0 1 1 1 1 PIN domain DUF217 PF02697.9 AIF83665.1 - 2.4e-14 53.3 0.1 2.9e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1753 NYD-SP28_assoc PF14775.1 AIF83665.1 - 0.063 12.9 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain tRNA-synt_His PF13393.1 AIF83666.1 - 3.7e-39 134.6 0.5 4.6e-39 134.2 0.0 1.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AIF83666.1 - 2.2e-15 56.6 0.1 3.6e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AIF83666.1 - 3.4e-12 46.1 0.1 6.9e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 AIF83666.1 - 0.005 16.0 0.0 0.0078 15.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Archease PF01951.11 AIF83667.1 - 1.4e-38 131.9 0.9 1.6e-38 131.7 0.7 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) HSP20 PF00011.16 AIF83668.1 - 2.7e-21 75.3 2.1 2.7e-21 75.3 1.5 1.6 2 0 0 2 2 2 1 Hsp20/alpha crystallin family zinc_ribbon_2 PF13240.1 AIF83669.1 - 2.8e-07 29.8 4.0 5.1e-07 28.9 2.8 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF83669.1 - 8.9e-07 27.9 5.2 1.4e-06 27.3 3.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AIF83669.1 - 2e-05 24.3 1.2 3.1e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 AIF83669.1 - 0.0017 18.0 7.2 0.002 17.7 3.4 2.0 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 AIF83669.1 - 0.0036 16.9 3.5 0.82 9.4 0.2 2.4 2 0 0 2 2 2 2 Nudix N-terminal GFA PF04828.9 AIF83669.1 - 0.45 10.4 2.8 8.9 6.3 0.1 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 AIF83669.1 - 2.3 7.8 10.4 3.2 7.3 0.6 2.3 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.6 AIF83669.1 - 6.6 6.6 6.9 43 4.0 4.8 2.1 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.11 AIF83669.1 - 9.8 5.9 6.6 12 5.6 0.9 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit SnoaL_2 PF12680.2 AIF83670.1 - 1.8e-09 37.8 0.0 2.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 AIF83670.1 - 4.1e-08 32.8 0.1 5.5e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 AIF83670.1 - 0.077 13.0 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain Ferritin PF00210.19 AIF83671.1 - 6.2e-18 64.9 0.0 8.5e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AIF83671.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Rubrerythrin MIP PF00230.15 AIF83672.1 - 1.2e-53 181.8 23.8 1.4e-53 181.6 16.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1803 PF08820.5 AIF83673.1 - 0.0035 17.0 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1803) HTH_7 PF02796.10 AIF83674.1 - 0.00042 20.1 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DUF2250 PF10007.4 AIF83674.1 - 0.0011 18.7 0.0 0.0084 15.9 0.0 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_IclR PF09339.5 AIF83674.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_36 PF13730.1 AIF83674.1 - 0.0032 17.5 0.1 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 AIF83674.1 - 0.0042 16.4 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 AIF83674.1 - 0.0068 16.0 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Mga PF05043.8 AIF83674.1 - 0.0083 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_11 PF08279.7 AIF83674.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 HTH domain RAP1 PF07218.6 AIF83674.1 - 0.036 12.1 0.2 0.04 12.0 0.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HTH_23 PF13384.1 AIF83674.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Rrf2 PF02082.15 AIF83674.1 - 0.05 13.7 0.0 0.28 11.3 0.0 1.8 1 1 1 2 2 2 0 Transcriptional regulator HTH_26 PF13443.1 AIF83674.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain FUR PF01475.14 AIF83674.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family Phage_AlpA PF05930.7 AIF83674.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) XPG_I PF00867.13 AIF83675.1 - 3.3e-23 81.5 0.0 7.2e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AIF83675.1 - 2.9e-18 65.9 0.0 5.3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 AIF83675.1 - 2.8e-05 24.2 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Pectate_lyase_2 PF06917.7 AIF83675.1 - 0.078 11.2 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic pectate lyase HHH_5 PF14520.1 AIF83675.1 - 0.084 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_M50 PF02163.17 AIF83675.1 - 0.092 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M50 Effector_1 PF04518.7 AIF83676.1 - 0.087 11.8 0.2 0.088 11.7 0.2 1.0 1 0 0 1 1 1 0 Effector from type III secretion system MCM PF00493.18 AIF83677.1 - 1.3e-05 24.1 0.2 0.014 14.1 0.0 2.4 2 1 0 2 2 2 2 MCM2/3/5 family Sigma54_activat PF00158.21 AIF83677.1 - 2.2e-05 23.9 0.0 7.7e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 AIF83677.1 - 0.00069 19.2 0.0 0.0033 17.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AIF83677.1 - 0.0036 17.0 0.1 0.22 11.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AIF83677.1 - 0.0098 16.0 0.0 0.14 12.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 AIF83677.1 - 0.013 15.7 0.1 0.075 13.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AIF83677.1 - 0.085 12.5 0.1 1.2 8.7 0.1 2.5 2 1 0 2 2 2 0 DNA polymerase III, delta subunit Glyco_hydro_14 PF01373.12 AIF83678.1 - 5.7e-05 22.0 0.0 5.7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 zf-NADH-PPase PF09297.6 AIF83679.1 - 0.0043 16.5 3.4 0.059 12.8 0.5 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain TFIIS_C PF01096.13 AIF83679.1 - 0.015 14.9 2.7 0.37 10.4 0.1 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 AIF83679.1 - 0.034 14.1 5.6 4.9 7.1 3.8 2.2 1 1 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 AIF83679.1 - 0.047 13.0 0.8 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.2 AIF83679.1 - 0.049 13.4 1.1 0.07 12.9 0.7 1.2 1 0 0 1 1 1 0 Double zinc ribbon UbiA PF01040.13 AIF83679.1 - 0.49 9.5 6.0 0.57 9.3 4.2 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Ogr_Delta PF04606.7 AIF83679.1 - 0.55 9.9 5.2 0.96 9.1 0.7 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.1 AIF83679.1 - 0.71 9.4 4.4 9.7 5.8 3.0 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF83679.1 - 0.96 8.7 4.8 14 4.9 3.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AIF83679.1 - 1.6 8.6 5.9 3.5 7.5 0.5 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Prok-JAB PF14464.1 AIF83681.1 - 9.6e-09 34.7 0.0 3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain PqqD PF05402.7 AIF83682.1 - 9.3e-07 28.7 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) PI3_PI4_kinase PF00454.22 AIF83682.1 - 0.089 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DUF1129 PF06570.6 AIF83684.1 - 0.078 12.2 1.2 0.12 11.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) AzlD PF05437.7 AIF83684.1 - 0.096 12.6 1.6 0.14 12.0 1.1 1.4 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) RicinB_lectin_2 PF14200.1 AIF83685.1 - 0.081 13.3 0.1 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like 7TMR-DISM_7TM PF07695.6 AIF83687.1 - 0.033 13.8 5.8 0.043 13.4 4.0 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling TcpE PF12648.2 AIF83687.1 - 0.35 11.0 9.5 0.069 13.2 1.1 2.0 1 1 1 2 2 2 0 TcpE family DUF4131 PF13567.1 AIF83687.1 - 1.3 8.4 6.4 4.2 6.7 4.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 AIF83687.1 - 1.7 8.0 8.4 1.9 7.8 5.9 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Abhydrolase_1 PF00561.15 AIF83688.1 - 9.2e-14 51.5 0.0 2.9e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold PhaC_N PF07167.8 AIF83688.1 - 1.5e-12 47.3 0.0 3.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_6 PF12697.2 AIF83688.1 - 6.1e-11 42.6 0.0 9.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIF83688.1 - 4.6e-08 32.9 0.0 2.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF3141 PF11339.3 AIF83688.1 - 0.00028 19.3 0.2 0.00065 18.1 0.0 1.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3141) PHB_depo_C PF06850.6 AIF83688.1 - 0.0019 17.4 0.0 0.014 14.6 0.0 2.0 2 0 0 2 2 2 1 PHB de-polymerase C-terminus DLH PF01738.13 AIF83688.1 - 0.0044 16.3 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1626 PF07788.6 AIF83688.1 - 0.03 14.0 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1626) BAAT_C PF08840.6 AIF83688.1 - 0.081 12.6 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PHA_synth_III_E PF09712.5 AIF83689.1 - 8.5e-18 64.7 0.5 4.7e-17 62.3 0.1 1.8 1 1 1 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) SRP1_TIP1 PF00660.12 AIF83689.1 - 0.00015 21.4 1.2 0.0013 18.5 0.5 2.7 2 1 0 2 2 2 1 Seripauperin and TIP1 family Phasin PF05597.6 AIF83689.1 - 0.0093 15.7 0.1 0.015 15.0 0.1 1.3 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2730 PF10805.3 AIF83689.1 - 0.01 15.5 1.1 0.16 11.6 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF4413 PF14372.1 AIF83689.1 - 0.039 13.9 1.7 0.14 12.1 0.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) Monooxygenase_B PF04744.7 AIF83690.1 - 0.045 12.4 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 Monooxygenase subunit B protein Gryzun-like PF12742.2 AIF83690.1 - 0.078 12.7 0.0 13 5.6 0.0 2.5 1 1 1 2 2 2 0 Gryzun, putative Golgi trafficking DUF4149 PF13664.1 AIF83691.1 - 0.062 13.3 0.7 0.18 11.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) ATP-grasp_5 PF13549.1 AIF83692.1 - 1.9e-64 216.9 0.3 2.7e-64 216.4 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 AIF83692.1 - 4.7e-46 155.8 0.1 1.6e-45 154.0 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AIF83692.1 - 5.8e-21 74.8 0.0 1.6e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 AIF83692.1 - 2.7e-11 43.8 0.3 1.4e-10 41.5 0.2 2.4 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_4 PF13535.1 AIF83692.1 - 0.00035 20.3 0.0 0.001 18.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 AIF83692.1 - 0.0075 15.6 0.2 0.019 14.3 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AIF83692.1 - 0.019 14.3 0.1 0.06 12.6 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain F420_oxidored PF03807.12 AIF83692.1 - 0.059 13.8 0.1 0.27 11.6 0.1 2.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GATase PF00117.23 AIF83693.1 - 2.8e-22 79.1 0.0 3.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIF83693.1 - 3.2e-07 30.0 0.0 7.4e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 AIF83693.1 - 0.059 12.8 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.9 AIF83693.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Toprim_4 PF13662.1 AIF83694.1 - 4.9e-07 29.6 0.0 7.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.17 AIF83694.1 - 3.3e-05 23.8 0.0 0.0039 17.1 0.0 2.3 1 1 0 1 1 1 1 Toprim domain RinB PF06116.7 AIF83694.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional activator RinB Toprim_2 PF13155.1 AIF83694.1 - 0.039 14.2 0.0 0.057 13.7 0.0 1.5 1 1 0 1 1 1 0 Toprim-like Hydrolase_6 PF13344.1 AIF83694.1 - 0.093 12.6 0.1 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Toprim_4 PF13662.1 AIF83695.1 - 5.3e-09 35.9 1.3 9.3e-09 35.1 0.3 1.9 2 0 0 2 2 2 1 Toprim domain Toprim PF01751.17 AIF83695.1 - 0.0096 15.8 0.6 0.048 13.6 0.4 2.2 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 AIF83695.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 Toprim-like GRP PF07172.6 AIF83695.1 - 0.081 13.4 12.1 0.15 12.5 8.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family CTP-dep_RFKase PF01982.11 AIF83696.1 - 1.9e-41 140.4 0.0 2.7e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF120 MarR_2 PF12802.2 AIF83696.1 - 0.00019 21.0 0.1 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 AIF83696.1 - 0.00063 19.4 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.1 AIF83696.1 - 0.0062 16.5 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.17 AIF83696.1 - 0.0089 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF83696.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 AIF83696.1 - 0.03 14.6 0.1 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_11 PF08279.7 AIF83696.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 HTH domain HlyD_2 PF12700.2 AIF83696.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein CTP_transf_2 PF01467.21 AIF83697.1 - 2.9e-08 33.9 0.4 1.1e-07 32.0 0.3 1.9 1 1 0 1 1 1 1 Cytidylyltransferase MazG PF03819.12 AIF83697.1 - 0.0027 17.5 0.1 0.97 9.4 0.0 2.6 2 1 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain Methyltransf_31 PF13847.1 AIF83698.1 - 7.4e-29 100.3 0.0 2.7e-28 98.4 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF83698.1 - 4.2e-18 65.5 0.0 1.5e-17 63.7 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83698.1 - 1.6e-16 60.5 0.0 2.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF83698.1 - 7e-16 58.5 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF83698.1 - 8.8e-16 58.4 0.0 3.1e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF83698.1 - 9.8e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 AIF83698.1 - 4.9e-08 32.5 0.0 8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 AIF83698.1 - 5.4e-08 32.1 0.0 1.8e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 AIF83698.1 - 8.7e-08 31.5 0.0 1.7e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AIF83698.1 - 2.4e-07 30.7 0.0 5.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIF83698.1 - 3.3e-07 29.6 0.0 5.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 AIF83698.1 - 3.3e-05 23.5 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 AIF83698.1 - 0.00011 21.1 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 AIF83698.1 - 0.00094 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 AIF83698.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 AIF83698.1 - 0.0032 16.6 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_9 PF08003.6 AIF83698.1 - 0.0048 15.6 0.0 0.0072 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FmrO PF07091.6 AIF83698.1 - 0.0079 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) DUF938 PF06080.7 AIF83698.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF938) Methyltransf_32 PF13679.1 AIF83698.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF650 PF04894.7 AIF83699.1 - 2.7e-82 276.3 0.0 3.9e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF650) DUF651 PF04895.7 AIF83699.1 - 1.6e-37 127.4 0.0 2.7e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF651) Psb28 PF03912.9 AIF83700.1 - 0.084 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Psb28 protein ProRS-C_1 PF09180.6 AIF83701.1 - 3.9e-24 84.3 0.3 9.7e-24 83.0 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 AIF83701.1 - 2.2e-20 72.3 0.6 4.4e-20 71.4 0.4 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 AIF83701.1 - 2.5e-18 66.2 0.0 4.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) SNARE_assoc PF09335.6 AIF83702.1 - 3.4e-16 59.5 2.4 3.4e-16 59.5 1.6 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein Nramp PF01566.13 AIF83702.1 - 0.12 11.1 5.5 0.27 9.9 0.5 2.2 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein DUF824 PF05688.6 AIF83703.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DUF2387 PF09526.5 AIF83704.1 - 0.00046 20.0 0.9 0.0005 19.9 0.6 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) zinc_ribbon_4 PF13717.1 AIF83704.1 - 0.0014 18.2 0.9 0.32 10.7 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF83704.1 - 0.0018 17.8 1.2 0.35 10.4 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain C1_4 PF07975.7 AIF83704.1 - 0.013 15.4 2.4 0.032 14.2 1.7 1.6 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 AIF83704.1 - 0.031 14.0 0.5 0.035 13.9 0.3 1.1 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-TFIIB PF13453.1 AIF83704.1 - 0.038 13.1 3.2 0.07 12.3 2.2 1.5 1 1 0 1 1 1 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.6 AIF83704.1 - 0.074 12.7 0.7 0.076 12.6 0.5 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 AIF83704.1 - 0.075 12.8 0.6 0.1 12.4 0.4 1.3 1 1 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.5 AIF83704.1 - 0.088 12.7 1.1 9.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 AIF83704.1 - 0.098 12.4 0.1 0.13 12.0 0.1 1.3 1 1 0 1 1 1 0 PhnA Zinc-Ribbon C1_1 PF00130.17 AIF83704.1 - 0.16 11.7 0.7 0.19 11.5 0.5 1.1 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_POL_M_15KD PF02150.11 AIF83704.1 - 0.26 11.0 1.9 1.3 8.7 1.3 1.9 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Auto_anti-p27 PF06677.7 AIF83704.1 - 0.27 11.0 4.2 0.45 10.3 2.9 1.6 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TFIIS_C PF01096.13 AIF83704.1 - 0.85 9.3 4.4 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.1 AIF83704.1 - 9 6.7 7.6 2.1 8.7 0.2 2.1 1 1 1 2 2 2 0 Zinc-finger double domain SMC_N PF02463.14 AIF83705.1 - 1.2e-58 197.9 12.9 9.3e-58 195.0 9.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIF83705.1 - 3.9e-17 63.1 0.2 2.6e-08 34.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 AIF83705.1 - 6.8e-16 58.3 0.0 2.8e-15 56.3 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 AIF83705.1 - 4.8e-14 53.1 25.2 4.8e-14 53.1 17.5 6.0 2 2 1 3 3 2 1 AAA domain AAA_15 PF13175.1 AIF83705.1 - 3.1e-07 29.7 1.7 1.1e-05 24.6 1.2 3.9 3 1 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 AIF83705.1 - 2.1e-06 27.1 0.0 4.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 AIF83705.1 - 2.6e-05 23.5 36.2 0.0082 15.3 0.4 5.1 2 2 3 6 6 6 5 Reovirus sigma C capsid protein AAA_13 PF13166.1 AIF83705.1 - 9e-05 21.1 72.4 0.024 13.1 8.8 6.2 4 2 2 6 6 6 3 AAA domain CENP-F_leu_zip PF10473.4 AIF83705.1 - 0.00019 21.3 30.1 0.00055 19.8 10.9 6.9 4 3 3 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 AIF83705.1 - 0.00041 18.7 74.1 0.034 12.3 6.5 4.2 3 2 1 4 4 4 3 Plant protein of unknown function (DUF869) DUF812 PF05667.6 AIF83705.1 - 0.00091 17.8 12.0 0.00091 17.8 8.4 4.1 2 2 2 4 4 4 1 Protein of unknown function (DUF812) BRE1 PF08647.6 AIF83705.1 - 0.0021 18.0 9.9 0.0021 18.0 6.9 7.0 4 3 2 6 6 4 1 BRE1 E3 ubiquitin ligase DUF3450 PF11932.3 AIF83705.1 - 0.006 15.8 8.7 0.006 15.8 6.0 6.4 2 2 3 6 6 6 1 Protein of unknown function (DUF3450) ABC_tran PF00005.22 AIF83705.1 - 0.015 15.6 0.5 0.015 15.6 0.3 5.8 2 2 2 4 4 3 0 ABC transporter AAA_25 PF13481.1 AIF83705.1 - 0.028 13.8 0.8 1.2 8.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 AIF83705.1 - 0.088 12.7 0.0 0.088 12.7 0.0 4.3 3 2 0 4 4 2 0 AAA ATPase domain MscS_porin PF12795.2 AIF83705.1 - 0.81 8.9 82.2 0.031 13.5 5.5 6.3 2 2 4 6 6 6 0 Mechanosensitive ion channel porin domain DUF4200 PF13863.1 AIF83705.1 - 1.5 8.7 82.6 1 9.2 4.5 8.3 3 3 5 8 8 8 0 Domain of unknown function (DUF4200) DUF4201 PF13870.1 AIF83705.1 - 1.7 8.0 61.6 0.053 12.9 2.9 6.7 3 2 3 6 6 5 0 Domain of unknown function (DUF4201) Cast PF10174.4 AIF83705.1 - 2.5 6.0 83.6 0.0062 14.6 13.5 4.3 3 1 1 4 4 4 0 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 AIF83705.1 - 2.5 6.6 81.5 0.12 10.9 6.2 5.9 2 2 2 5 5 5 0 Spc7 kinetochore protein AAA_17 PF13207.1 AIF83705.1 - 4.2 8.1 11.3 39 5.0 2.9 4.6 2 2 0 2 2 2 0 AAA domain MtrG PF04210.8 AIF83705.1 - 8.3 6.1 11.6 14 5.4 0.0 5.4 5 1 1 6 6 6 0 Tetrahydromethanopterin S-methyltransferase, subunit G NAD_binding_5 PF07994.7 AIF83706.1 - 2.9e-49 168.1 0.0 2.9e-48 164.8 0.0 1.9 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 AIF83706.1 - 3.8e-26 91.1 0.0 6e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Acetyltransf_7 PF13508.1 AIF83707.1 - 1.2e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AIF83707.1 - 0.00057 19.8 0.0 0.0019 18.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AIF83707.1 - 0.08 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein tRNA-synt_1e PF01406.14 AIF83708.1 - 9.6e-70 235.0 0.0 1.6e-69 234.3 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AIF83708.1 - 1.4e-15 56.8 0.1 6.8e-08 31.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AIF83708.1 - 8.6e-09 33.9 0.0 2.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 AIF83708.1 - 6.8e-07 28.2 0.0 0.0039 15.9 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.14 AIF83708.1 - 0.00036 19.4 0.3 0.35 9.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_2 PF09190.6 AIF83708.1 - 0.00069 19.8 2.0 0.0028 17.8 0.6 2.4 1 1 1 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 AIF83708.1 - 0.03 12.9 0.5 0.13 10.9 0.1 2.1 2 1 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Radical_SAM PF04055.16 AIF83709.1 - 3.9e-16 59.6 0.4 6.8e-16 58.8 0.3 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 AIF83709.1 - 2.8e-05 24.1 0.2 6.2e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AIF83709.1 - 8.4e-05 22.7 0.1 0.00025 21.1 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain SPASM PF13186.1 AIF83709.1 - 0.003 17.8 0.7 0.0071 16.6 0.5 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain HAD_2 PF13419.1 AIF83709.1 - 0.1 12.8 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LysE PF01810.13 AIF83710.1 - 1.2e-17 63.8 16.6 1.4e-17 63.5 11.5 1.1 1 0 0 1 1 1 1 LysE type translocator Alba PF01918.16 AIF83711.1 - 3.2e-12 45.8 0.3 4.3e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 AIF83711.1 - 0.019 14.5 0.2 0.032 13.8 0.1 1.4 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P SGL PF08450.7 AIF83713.1 - 5.1e-12 45.6 1.6 0.00061 19.2 0.0 5.1 4 1 1 5 5 5 3 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 AIF83713.1 - 9.5e-08 31.1 4.6 12 6.3 0.0 6.8 6 0 0 6 6 6 1 Two component regulator propeller DUF1034 PF06280.7 AIF83713.1 - 0.00014 22.2 1.3 0.5 10.8 0.4 2.5 1 1 1 2 2 2 2 Fn3-like domain (DUF1034) SBBP PF06739.6 AIF83713.1 - 0.00049 19.8 4.5 0.32 10.8 0.1 4.2 4 0 0 4 4 4 2 Beta-propeller repeat NHL PF01436.16 AIF83713.1 - 0.0005 19.8 2.4 2.5 8.2 0.0 4.9 6 0 0 6 6 6 2 NHL repeat Wzt_C PF14524.1 AIF83713.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Wzt C-terminal domain Kelch_2 PF07646.10 AIF83713.1 - 0.1 12.3 1.4 6.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Kelch motif DUF4097 PF13349.1 AIF83713.1 - 0.34 10.4 2.5 3 7.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) EamA PF00892.15 AIF83714.1 - 6.1e-32 110.3 33.6 1.1e-17 64.1 5.1 2.3 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 AIF83714.1 - 2.7e-08 33.9 34.4 6.4e-05 23.1 3.3 3.2 2 2 2 4 4 4 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 AIF83714.1 - 0.33 10.7 0.1 0.33 10.7 0.1 2.8 3 1 0 3 3 3 0 Uncharacterised protein family UPF0546 PTH2 PF01981.11 AIF83715.1 - 6e-46 154.8 0.1 6.7e-46 154.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 FAD_binding_3 PF01494.14 AIF83716.1 - 1.2e-09 37.6 0.3 1e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AIF83716.1 - 1.4e-07 30.7 4.7 0.00083 18.3 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AIF83716.1 - 1.1e-06 28.0 0.5 1.7e-06 27.4 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AIF83716.1 - 2.9e-06 26.0 0.8 0.0015 17.1 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.9 AIF83716.1 - 0.00011 20.9 1.9 0.036 12.6 0.0 2.8 2 1 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 AIF83716.1 - 0.00065 18.8 0.9 0.0013 17.8 0.2 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 AIF83716.1 - 0.0057 15.5 1.3 0.01 14.7 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 AIF83716.1 - 0.0089 14.9 1.7 0.7 8.7 0.6 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 AIF83716.1 - 0.083 12.9 0.2 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AIF83716.1 - 0.23 11.4 4.1 0.22 11.5 0.3 2.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AIF83716.1 - 0.43 10.4 6.3 0.74 9.6 4.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 AIF83716.1 - 2.9 6.8 6.1 29 3.5 0.1 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DUF1610 PF07754.6 AIF83717.1 - 4.5e-05 23.4 20.3 7.1e-05 22.8 3.4 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF1610) IBR PF01485.16 AIF83717.1 - 0.18 11.7 11.7 0.58 10.0 8.1 1.8 1 1 0 1 1 1 0 IBR domain DZR PF12773.2 AIF83717.1 - 0.2 11.4 13.3 2.6 7.9 3.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon DUF2321 PF10083.4 AIF83717.1 - 0.25 10.8 2.0 0.27 10.7 1.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) PolC_DP2 PF03833.8 AIF83717.1 - 0.3 8.6 6.4 0.34 8.5 4.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_1 PF00130.17 AIF83717.1 - 0.31 10.8 10.9 1.3 8.7 3.0 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CK_II_beta PF01214.13 AIF83717.1 - 0.35 10.3 2.8 0.4 10.1 1.9 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Zn_Tnp_IS1595 PF12760.2 AIF83717.1 - 1.3 8.9 15.1 0.58 10.0 7.2 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-UBP PF02148.14 AIF83717.1 - 3.5 7.8 7.4 7.4 6.7 0.4 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-B_box PF00643.19 AIF83717.1 - 5.7 6.9 13.9 26 4.7 7.1 2.6 1 1 1 2 2 2 0 B-box zinc finger DUF3716 PF12511.3 AIF83717.1 - 7 6.3 12.3 13 5.4 8.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) EF1_GNE PF00736.14 AIF83718.1 - 5.6e-17 61.2 0.1 6e-17 61.1 0.1 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain PH_3 PF14593.1 AIF83718.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 PH domain AAA PF00004.24 AIF83719.1 - 8.4e-92 304.2 0.0 3.4e-48 163.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AIF83719.1 - 1.4e-27 95.4 0.9 3.9e-27 94.0 0.1 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AIF83719.1 - 4.5e-14 52.7 0.0 2.4e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIF83719.1 - 4.4e-13 49.5 0.1 0.0013 18.9 0.0 4.4 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.7 AIF83719.1 - 7.9e-13 47.9 0.1 1.7e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AIF83719.1 - 1.6e-12 47.8 0.0 0.00011 22.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 AIF83719.1 - 1.1e-11 44.6 0.1 2.8e-05 23.8 0.0 4.3 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AIF83719.1 - 1.5e-11 44.2 0.0 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AIF83719.1 - 2.5e-11 44.4 0.9 4.2e-05 24.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.1 AIF83719.1 - 7.5e-10 38.8 0.0 5.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AIF83719.1 - 6.9e-09 35.3 4.8 0.092 12.1 0.1 4.4 2 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 AIF83719.1 - 7.3e-09 35.2 0.1 0.0035 16.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.8 AIF83719.1 - 2.7e-08 32.9 0.2 0.0039 15.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 AIF83719.1 - 1.5e-07 31.5 0.0 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 AIF83719.1 - 2.6e-07 30.7 0.0 0.0048 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AIF83719.1 - 3.5e-07 30.5 0.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 AIF83719.1 - 6.7e-07 29.2 0.1 0.0096 15.6 0.0 3.5 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activat PF00158.21 AIF83719.1 - 1.2e-06 28.1 0.2 0.1 12.0 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 AIF83719.1 - 1.4e-06 27.5 0.0 0.0063 15.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 AIF83719.1 - 1.5e-06 28.5 0.0 0.018 15.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.16 AIF83719.1 - 1.6e-06 27.4 0.7 0.0069 15.5 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 AIF83719.1 - 2e-06 27.8 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain CDC48_2 PF02933.12 AIF83719.1 - 3.8e-06 26.4 0.1 9.2e-06 25.2 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 PhoH PF02562.11 AIF83719.1 - 5e-06 25.8 2.2 0.15 11.2 0.0 3.4 2 1 0 3 3 3 2 PhoH-like protein KaiC PF06745.8 AIF83719.1 - 6.6e-06 25.4 0.4 0.29 10.2 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_19 PF13245.1 AIF83719.1 - 9.5e-06 25.2 1.3 0.029 14.0 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain ResIII PF04851.10 AIF83719.1 - 1.1e-05 25.3 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 AIF83719.1 - 1.4e-05 24.7 0.0 0.022 14.2 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 AIF83719.1 - 2.6e-05 23.9 0.6 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 AIF83719.1 - 4.4e-05 22.6 0.1 0.021 13.8 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 AIF83719.1 - 0.00013 20.9 0.2 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DEAD PF00270.24 AIF83719.1 - 0.00024 20.6 1.0 3.2 7.2 0.0 4.0 2 2 2 4 4 4 0 DEAD/DEAH box helicase DUF815 PF05673.8 AIF83719.1 - 0.00043 19.2 0.0 0.42 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 AIF83719.1 - 0.0011 18.6 0.0 0.44 10.1 0.0 3.0 3 0 0 3 3 2 1 Bacterial dnaA protein SKI PF01202.17 AIF83719.1 - 0.003 17.4 0.2 4.9 7.0 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase T2SE PF00437.15 AIF83719.1 - 0.003 16.4 0.1 1.2 7.9 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 AIF83719.1 - 0.0032 17.1 0.4 7.1 6.2 0.0 3.7 4 0 0 4 4 3 0 NACHT domain AAA_3 PF07726.6 AIF83719.1 - 0.0051 16.4 0.0 0.44 10.1 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AIF83719.1 - 0.0095 15.8 0.1 0.093 12.6 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Guanylate_kin PF00625.16 AIF83719.1 - 0.011 15.2 0.4 20 4.5 0.0 3.9 2 2 2 4 4 4 0 Guanylate kinase AAA_21 PF13304.1 AIF83719.1 - 0.011 15.7 3.0 1.3 8.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AIF83719.1 - 0.013 15.0 0.0 5.3 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 AIF83719.1 - 0.014 14.6 0.2 0.88 8.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 AIF83719.1 - 0.028 14.0 0.1 9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Herpes_TK PF00693.13 AIF83719.1 - 0.029 13.5 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase from herpesvirus AAA_23 PF13476.1 AIF83719.1 - 0.03 14.6 0.8 4.7 7.4 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AIF83719.1 - 0.035 13.6 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Disulph_isomer PF06491.6 AIF83719.1 - 0.036 13.8 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Disulphide isomerase SRPRB PF09439.5 AIF83719.1 - 0.063 12.4 0.0 19 4.4 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 AIF83719.1 - 0.12 11.8 0.4 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.10 AIF83719.1 - 0.14 10.8 0.0 8.3 4.9 0.0 2.7 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 AIF83719.1 - 0.16 10.7 0.1 14 4.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF258 PF03193.11 AIF83719.1 - 0.2 10.8 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 AIF83719.1 - 0.51 10.0 4.1 38 3.9 0.0 4.2 3 2 1 4 4 4 0 NTPase DUF1456 PF07308.8 AIF83721.1 - 0.0082 16.1 0.2 0.0099 15.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1456) PepSY_2 PF13670.1 AIF83721.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain UbiA PF01040.13 AIF83722.1 - 2.3e-31 108.9 25.8 2.9e-31 108.6 17.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2207 PF09972.4 AIF83722.1 - 1.3 7.5 4.2 2.6 6.5 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PepSY_TM_3 PF13706.1 AIF83722.1 - 4.4 6.8 16.4 14 5.1 0.4 4.0 3 0 0 3 3 3 0 PepSY-associated TM helix Copper-bind PF00127.15 AIF83724.1 - 1.2e-16 60.7 2.7 7.9e-08 32.4 0.1 2.8 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF83724.1 - 2.9e-15 56.0 0.1 1.4e-08 34.5 0.0 2.5 2 1 0 2 2 2 2 Cupredoxin-like domain DUF2360 PF10152.4 AIF83724.1 - 0.023 14.9 2.0 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2061 PF09834.4 AIF83724.1 - 0.04 14.1 2.2 0.18 11.9 1.5 2.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) Prok-JAB PF14464.1 AIF83725.1 - 1.5e-14 53.3 0.0 1.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 AIF83725.1 - 2e-06 27.5 0.0 3.5e-06 26.7 0.0 1.4 1 1 1 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA-synt_2 PF00152.15 AIF83726.1 - 9.7e-87 290.8 0.0 1.3e-86 290.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AIF83726.1 - 9.4e-11 41.4 0.6 1.7e-10 40.6 0.4 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AIF83726.1 - 0.00018 20.7 0.2 0.047 12.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) KH_5 PF13184.1 AIF83727.1 - 4.6e-06 26.3 0.1 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 NusA-like KH domain TIG PF01833.19 AIF83731.1 - 0.00048 20.0 1.2 0.00092 19.1 0.8 1.6 1 1 0 1 1 1 1 IPT/TIG domain Enolase_N PF03952.11 AIF83731.1 - 0.053 13.4 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Enolase, N-terminal domain A2M_N PF01835.14 AIF83731.1 - 0.062 13.5 0.1 0.096 12.9 0.0 1.6 1 1 0 1 1 1 0 MG2 domain Qn_am_d_aIII PF09099.5 AIF83731.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Big_3_4 PF13754.1 AIF83731.1 - 0.87 9.9 6.7 0.14 12.4 1.3 2.1 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) TPD52 PF04201.10 AIF83732.1 - 0.0014 18.3 0.7 0.0019 17.9 0.5 1.3 1 0 0 1 1 1 1 Tumour protein D52 family DUF1995 PF09353.5 AIF83732.1 - 0.035 13.7 5.8 2.8 7.5 4.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) UpxZ PF06603.6 AIF83732.1 - 0.036 14.0 0.2 0.085 12.8 0.0 1.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists EspB PF05802.6 AIF83732.1 - 0.14 11.0 12.1 1.7 7.4 8.1 2.0 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF1241 PF06840.6 AIF83732.1 - 0.17 11.1 2.3 0.14 11.4 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Phasin_2 PF09361.5 AIF83732.1 - 0.23 11.5 12.2 1.1 9.3 0.2 3.1 1 1 2 3 3 3 0 Phasin protein Sec20 PF03908.8 AIF83732.1 - 0.86 9.3 6.0 0.86 9.3 0.1 2.5 2 1 1 3 3 3 0 Sec20 DUF4200 PF13863.1 AIF83732.1 - 1.3 8.9 9.5 0.23 11.4 3.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Phe_tRNA-synt_N PF02912.13 AIF83732.1 - 1.3 8.7 4.4 1.3 8.7 0.7 2.4 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain YtxH PF12732.2 AIF83732.1 - 1.4 9.3 7.7 23 5.4 5.3 2.5 1 1 0 1 1 1 0 YtxH-like protein ATP-synt_B PF00430.13 AIF83732.1 - 6.2 6.6 16.8 0.13 12.1 3.2 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) OmpH PF03938.9 AIF83732.1 - 7.6 6.4 11.8 1.4e+02 2.3 8.2 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIVA PF05103.8 AIF83732.1 - 9.5 6.2 14.3 7.1 6.6 2.1 2.3 2 0 0 2 2 2 0 DivIVA protein DUF2171 PF09939.4 AIF83734.1 - 0.064 13.2 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) PRC PF05239.11 AIF83734.1 - 0.3 10.9 3.3 4.7 7.1 0.0 3.3 2 1 1 3 3 3 0 PRC-barrel domain ABC_tran PF00005.22 AIF83735.1 - 2.4e-24 86.1 0.0 3.7e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 AIF83735.1 - 5.8e-23 81.0 0.4 1.1e-22 80.1 0.3 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 AIF83735.1 - 5.7e-13 49.4 0.4 1.2e-09 38.5 0.1 2.2 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AIF83735.1 - 0.00065 19.7 0.2 0.0018 18.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 AIF83735.1 - 0.0011 18.1 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 AIF83735.1 - 0.0023 17.2 0.6 0.015 14.5 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 AIF83735.1 - 0.0043 17.3 0.0 0.07 13.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIF83735.1 - 0.0097 15.3 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 AIF83735.1 - 0.01 14.4 0.4 0.75 8.3 0.1 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.20 AIF83735.1 - 0.023 14.2 0.2 0.2 11.1 0.2 2.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 AIF83735.1 - 0.058 13.5 1.5 1.6 8.8 1.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIF83735.1 - 0.13 11.7 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AIF83735.1 - 0.14 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 AIF83735.1 - 0.16 11.3 0.5 15 4.8 0.2 2.1 1 1 0 2 2 2 0 AAA-like domain Helicase_C_2 PF13307.1 AIF83736.1 - 1.1e-21 77.5 0.1 2.6e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 AIF83736.1 - 4.4e-07 29.9 0.2 7.9e-05 22.5 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 AIF83736.1 - 4.2e-06 26.2 0.0 7.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 AIF83736.1 - 9e-05 22.0 0.0 0.54 9.7 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_10 PF12846.2 AIF83736.1 - 0.00092 18.7 0.0 0.45 9.8 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain Exosortase_EpsH PF09721.5 AIF83737.1 - 8.7e-05 21.8 23.6 0.00031 20.0 16.4 2.0 1 1 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) IMS PF00817.15 AIF83738.1 - 1e-40 138.9 0.7 3.6e-40 137.1 0.1 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 AIF83738.1 - 9e-09 35.3 0.1 1.4e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain HHH_5 PF14520.1 AIF83738.1 - 1.3e-07 31.6 0.0 5e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.3 AIF83738.1 - 1.2e-06 28.2 0.0 2.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.3 AIF83738.1 - 0.0014 18.5 0.1 0.022 14.6 0.0 2.8 3 1 0 3 3 3 1 Pathogenicity locus HHH PF00633.18 AIF83738.1 - 0.021 14.5 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif 7TMR-HDED PF07697.6 AIF83738.1 - 0.028 14.1 0.3 0.057 13.1 0.2 1.5 1 0 0 1 1 1 0 7TM-HD extracellular CorA PF01544.13 AIF83738.1 - 0.16 11.0 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PGK PF00162.14 AIF83739.1 - 6e-132 439.8 0.0 6.8e-132 439.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FMN_red PF03358.10 AIF83739.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF929 PF06053.6 AIF83740.1 - 9.9e-24 83.7 0.0 2.1e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF929) AhpC-TSA PF00578.16 AIF83740.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Ribosomal_L16 PF00252.13 AIF83741.1 - 5.5e-28 97.3 0.2 7.2e-28 96.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA_int_endo PF01974.12 AIF83742.1 - 2.7e-19 68.7 0.2 5.4e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AIF83742.1 - 3.3e-08 32.9 0.3 6.3e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain tRNA_int_end_N2 PF12928.2 AIF83742.1 - 0.054 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term CreA PF05981.7 AIF83743.1 - 0.0096 15.4 0.0 0.0099 15.4 0.0 1.0 1 0 0 1 1 1 1 CreA protein Robl_LC7 PF03259.12 AIF83744.1 - 0.018 14.6 0.0 0.18 11.4 0.0 2.1 1 1 0 1 1 1 0 Roadblock/LC7 domain Ribosomal_L32p PF01783.18 AIF83745.1 - 0.014 15.5 2.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L32p protein family HypA PF01155.14 AIF83745.1 - 0.037 13.6 2.0 0.05 13.2 1.4 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Opy2 PF09463.5 AIF83745.1 - 0.095 12.7 5.0 0.12 12.5 1.6 2.0 2 0 0 2 2 2 0 Opy2 protein DZR PF12773.2 AIF83745.1 - 0.15 11.9 9.2 7.2 6.5 6.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF2797 PF10977.3 AIF83745.1 - 0.22 11.1 3.1 0.25 10.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF2039 PF10217.4 AIF83745.1 - 0.28 11.2 4.0 0.36 10.8 2.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-C3HC4_3 PF13920.1 AIF83745.1 - 0.33 10.6 8.2 0.67 9.6 5.7 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.7 AIF83745.1 - 0.89 9.3 6.7 2.7 7.8 4.7 1.7 1 1 1 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.1 AIF83745.1 - 0.89 9.1 8.4 6.8 6.3 5.8 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 AIF83745.1 - 2.6 7.8 11.0 1.3e+02 2.4 7.7 2.2 1 1 0 1 1 1 0 zinc-RING finger domain DUF1272 PF06906.6 AIF83745.1 - 2.9 7.7 8.0 20 5.1 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zinc_ribbon_2 PF13240.1 AIF83745.1 - 4.8 6.7 10.9 16 5.1 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF83745.1 - 6.7 6.0 9.4 14 5.0 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AIF83745.1 - 7.9 6.0 7.6 9.2 5.8 0.1 2.8 2 1 1 3 3 3 0 A2L zinc ribbon domain zf-C3HC4_3 PF13920.1 AIF83747.1 - 0.0027 17.3 1.6 0.0039 16.8 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2719 PF10891.3 AIF83747.1 - 0.015 15.0 2.7 0.022 14.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2719) Zn-ribbon_8 PF09723.5 AIF83747.1 - 0.15 12.0 4.1 18 5.3 0.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Opy2 PF09463.5 AIF83747.1 - 0.35 10.9 4.0 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Opy2 protein UPF0547 PF10571.4 AIF83747.1 - 0.54 9.9 5.4 0.39 10.4 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Baculo_IE-1 PF05290.6 AIF83747.1 - 1.4 8.6 5.5 2.9 7.6 3.7 1.7 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) DNA_ligase_ZBD PF03119.11 AIF83747.1 - 4.1 7.1 6.9 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain TRAM PF01938.15 AIF83749.1 - 1.1e-13 50.7 1.7 1.5e-13 50.3 1.2 1.2 1 0 0 1 1 1 1 TRAM domain DUF1908 PF08926.6 AIF83749.1 - 0.099 11.3 0.1 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) zf-C2H2_6 PF13912.1 AIF83750.1 - 0.0011 18.8 0.3 0.0015 18.3 0.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AIF83750.1 - 0.0057 16.9 0.7 0.0086 16.3 0.5 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF83750.1 - 0.043 14.1 0.4 0.056 13.8 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.7 AIF83750.1 - 0.13 11.9 1.1 0.17 11.5 0.7 1.3 1 0 0 1 1 1 0 DBF zinc finger CBS PF00571.23 AIF83751.1 - 2.4e-21 75.2 1.5 8.4e-13 47.8 0.2 2.1 2 0 0 2 2 2 2 CBS domain zinc_ribbon_2 PF13240.1 AIF83755.1 - 1.1e-05 24.7 5.9 1.1e-05 24.7 4.1 2.0 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 AIF83755.1 - 0.00011 21.9 2.4 0.00031 20.4 1.7 1.7 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF83755.1 - 0.00026 20.1 5.6 0.00026 20.1 3.9 2.1 2 0 0 2 2 2 1 zinc-ribbon domain TGS PF02824.16 AIF83756.1 - 7.2e-21 73.7 0.0 1.6e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AIF83756.1 - 1.5e-19 70.0 0.0 4.1e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AIF83756.1 - 5.5e-15 54.9 0.2 5.9e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 AIF83756.1 - 0.00011 21.5 0.3 0.037 13.2 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 AIF83756.1 - 0.00085 18.7 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AIG1 PF04548.11 AIF83756.1 - 0.00087 18.4 0.1 0.0032 16.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family cobW PF02492.14 AIF83756.1 - 0.00087 18.7 0.3 0.64 9.4 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 AIF83756.1 - 0.0013 17.9 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 AIF83756.1 - 0.0023 17.1 0.1 0.0095 15.1 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AIF83756.1 - 0.0028 17.4 0.0 0.28 10.9 0.1 2.6 1 1 1 2 2 2 1 Dynamin family AAA_28 PF13521.1 AIF83756.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 AIF83756.1 - 0.021 15.3 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 AIF83756.1 - 0.033 14.3 0.0 0.15 12.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain DNA_pol_A PF00476.15 AIF83756.1 - 0.034 12.7 0.0 0.056 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family A ArgK PF03308.11 AIF83756.1 - 0.035 12.8 0.0 0.073 11.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 AIF83756.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 AIF83756.1 - 0.06 12.1 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_16 PF13191.1 AIF83756.1 - 0.13 12.2 0.1 0.29 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 AIF83756.1 - 0.14 13.0 0.1 0.59 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Cupredoxin_1 PF13473.1 AIF83757.1 - 1.4e-08 34.5 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 AIF83757.1 - 0.02 15.1 0.3 0.038 14.2 0.2 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family TRAM PF01938.15 AIF83758.1 - 1e-12 47.5 0.9 1.3e-12 47.2 0.6 1.1 1 0 0 1 1 1 1 TRAM domain DUF108 PF01958.13 AIF83759.1 - 9.7e-37 125.0 0.5 2.2e-36 123.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.11 AIF83759.1 - 1.6e-22 80.0 0.2 2.8e-22 79.3 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 AIF83759.1 - 5.7e-07 30.0 0.3 1.3e-06 28.8 0.1 1.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.14 AIF83759.1 - 0.00058 20.3 0.3 0.0015 19.0 0.2 1.7 1 0 0 1 1 1 1 CoA binding domain NAD_binding_2 PF03446.10 AIF83759.1 - 0.0063 16.3 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 AIF83759.1 - 0.0071 16.6 0.2 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AIF83759.1 - 0.013 15.2 0.2 0.022 14.5 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 AIF83759.1 - 0.013 14.6 0.1 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AIF83759.1 - 0.047 14.1 0.5 0.1 13.0 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 AIF83759.1 - 0.19 11.3 3.7 1.1 8.8 2.6 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 AIF83759.1 - 0.69 9.7 5.8 2.4 7.9 3.0 2.3 2 1 0 2 2 2 0 ThiF family Ribosomal_S30 PF04758.9 AIF83760.1 - 5.3e-09 35.6 5.7 6.9e-09 35.3 3.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 NadA PF02445.11 AIF83763.1 - 5.5e-118 393.0 6.0 6.2e-118 392.8 4.1 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein QRPTase_C PF01729.14 AIF83764.1 - 2.6e-50 170.2 0.5 3.6e-50 169.7 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 AIF83764.1 - 8.3e-27 92.8 0.3 1.5e-26 92.0 0.2 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 AIF83764.1 - 0.011 14.8 0.1 0.027 13.6 0.0 1.6 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Spt4 PF06093.8 AIF83765.1 - 1.1e-12 47.6 0.1 1.4e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.10 AIF83765.1 - 0.00058 19.2 0.8 0.00081 18.7 0.5 1.2 1 0 0 1 1 1 1 RecR protein Laminin_EGF PF00053.19 AIF83765.1 - 0.045 13.6 0.7 0.056 13.3 0.5 1.1 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) DZR PF12773.2 AIF83765.1 - 0.06 13.1 1.0 0.087 12.6 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 AIF83765.1 - 0.063 12.6 0.8 0.079 12.2 0.0 1.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-FPG_IleRS PF06827.9 AIF83765.1 - 0.072 12.7 2.1 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS SHS2_Rpb7-N PF03876.12 AIF83766.1 - 4e-18 65.3 0.0 6.3e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AIF83766.1 - 5.9e-14 51.9 0.1 1.1e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.1 AIF83766.1 - 0.0012 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 S1 domain ParA PF10609.4 AIF83767.1 - 1.4e-35 120.9 0.5 1.2e-34 117.9 0.2 2.2 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 AIF83767.1 - 6.5e-21 74.6 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 AIF83767.1 - 8e-21 73.8 0.0 2.2e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF59 AAA_31 PF13614.1 AIF83767.1 - 3.1e-11 43.4 0.1 1.9e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 AIF83767.1 - 4.6e-07 29.1 0.0 9.6e-07 28.1 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 AIF83767.1 - 2.6e-06 26.7 3.4 3.7e-06 26.2 0.8 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 AIF83767.1 - 3.7e-06 26.3 0.1 0.00083 18.6 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 AIF83767.1 - 0.00018 20.6 0.1 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein AAA_26 PF13500.1 AIF83767.1 - 0.00047 19.8 1.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AIF83767.1 - 0.0044 16.4 0.1 0.0091 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 AIF83767.1 - 0.0064 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain APS_kinase PF01583.15 AIF83767.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 AIF83767.1 - 0.098 11.8 0.1 0.31 10.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 AIF83767.1 - 1.2 8.9 3.8 1.2 8.9 0.7 2.2 2 0 0 2 2 2 0 Part of AAA domain DUF359 PF04019.7 AIF83768.1 - 1.4e-35 121.3 0.0 2.2e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF359) HEM4 PF02602.10 AIF83768.1 - 0.00097 18.4 0.2 0.0017 17.6 0.1 1.4 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD DZR PF12773.2 AIF83769.1 - 0.088 12.6 3.7 0.097 12.5 0.9 1.3 1 1 1 2 2 2 0 Double zinc ribbon DUF4428 PF14471.1 AIF83769.1 - 0.22 11.2 6.4 1.9 8.2 4.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) zf-CHY PF05495.7 AIF83769.1 - 0.3 11.2 4.8 0.71 10.0 1.4 1.9 1 1 1 2 2 2 0 CHY zinc finger zf-C2H2_jaz PF12171.3 AIF83769.1 - 0.41 10.8 3.2 0.96 9.6 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2318 PF10080.4 AIF83769.1 - 0.46 10.2 7.3 7.1 6.4 4.9 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) zf-CXXC PF02008.15 AIF83769.1 - 0.61 9.9 5.3 0.86 9.4 3.6 1.4 1 1 0 1 1 1 0 CXXC zinc finger domain zf-AN1 PF01428.11 AIF83769.1 - 0.89 9.4 4.1 1.8 8.5 2.8 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger zf-BED PF02892.10 AIF83769.1 - 2.4 7.9 5.2 3.5 7.4 0.2 2.1 1 1 1 2 2 2 0 BED zinc finger CARDB PF07705.6 AIF83770.1 - 0.029 14.4 0.0 0.087 12.8 0.0 1.8 1 1 1 2 2 2 0 CARDB DUF329 PF03884.9 AIF83771.1 - 0.0042 16.6 8.6 0.15 11.6 0.5 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF329) Lar_restr_allev PF14354.1 AIF83771.1 - 0.0078 16.4 13.3 3.6 7.9 4.3 3.1 2 1 0 2 2 2 2 Restriction alleviation protein Lar DnaJ_CXXCXGXG PF00684.14 AIF83771.1 - 0.011 15.7 10.9 0.06 13.4 7.4 2.1 1 1 0 1 1 1 0 DnaJ central domain zf-nanos PF05741.8 AIF83771.1 - 0.64 10.0 12.2 1.3 9.0 4.9 2.7 1 1 1 2 2 2 0 Nanos RNA binding domain Zn_Tnp_IS1595 PF12760.2 AIF83771.1 - 1.3 8.8 13.2 12 5.7 2.8 3.1 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Rad50_zn_hook PF04423.9 AIF83771.1 - 2.8 7.4 5.8 17 4.9 0.2 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.1 AIF83771.1 - 3.7 6.8 12.4 1.2 8.4 0.7 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 AIF83771.1 - 7.2 6.3 16.8 11 5.7 2.4 3.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIB PF13453.1 AIF83771.1 - 9.3 5.5 14.5 0.79 8.9 0.8 3.3 3 1 0 3 3 3 0 Transcription factor zinc-finger FAD-oxidase_C PF02913.14 AIF83772.1 - 4e-51 173.7 0.2 5.6e-51 173.2 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AIF83772.1 - 6.4e-34 116.4 0.0 1.4e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.1 AIF83773.1 - 1.4e-16 60.6 0.0 2.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF83773.1 - 1.8e-14 53.5 0.0 2.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83773.1 - 6e-14 52.3 0.0 9.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF83773.1 - 1.3e-13 51.2 0.0 2.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF83773.1 - 1.8e-13 51.0 0.0 3.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF83773.1 - 6.6e-11 42.4 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF83773.1 - 1.1e-09 37.7 0.0 1.2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 AIF83773.1 - 1.6e-09 37.3 0.0 2.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 AIF83773.1 - 1.7e-08 34.5 0.0 4.9e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AIF83773.1 - 9.7e-06 25.0 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 AIF83773.1 - 1.9e-05 24.0 0.0 3.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 AIF83773.1 - 3e-05 23.1 0.0 0.00015 20.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.6 AIF83773.1 - 5.1e-05 22.7 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 AIF83773.1 - 6.5e-05 21.7 0.0 9.4e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 AIF83773.1 - 0.03 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 AIF83773.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 AIF83773.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyoxalase_2 PF12681.2 AIF83774.1 - 3.8e-17 62.8 0.0 4.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF83774.1 - 4.8e-14 52.4 0.0 6.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 AIF83774.1 - 0.0032 17.4 0.0 0.035 14.1 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_31 PF13847.1 AIF83776.1 - 8.2e-18 64.4 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF83776.1 - 3e-16 59.6 0.1 7.2e-16 58.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF83776.1 - 2.8e-12 46.6 0.0 4.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF83776.1 - 3.8e-11 43.5 0.1 9.2e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF83776.1 - 1.1e-09 38.6 0.0 9e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF83776.1 - 2.5e-09 36.6 0.1 1.4e-07 30.8 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 AIF83776.1 - 8.3e-09 35.7 0.1 4.7e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF83776.1 - 7.5e-06 25.9 0.4 3.4e-05 23.8 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF83776.1 - 0.0048 16.2 0.3 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain zf-C2H2 PF00096.21 AIF83777.1 - 0.00038 20.6 0.4 0.00038 20.6 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 AIF83777.1 - 0.0044 17.1 0.1 0.0044 17.1 0.1 1.8 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 AIF83777.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 AIF83777.1 - 0.077 12.6 0.1 0.077 12.6 0.1 2.0 2 1 0 2 2 2 0 zinc-finger of a C2HC-type DUF4064 PF13273.1 AIF83779.1 - 0.0089 16.1 0.2 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Claudin_3 PF06653.6 AIF83779.1 - 0.03 14.0 0.2 0.036 13.7 0.2 1.0 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Claudin_2 PF13903.1 AIF83779.1 - 0.083 12.5 5.0 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 AIF83779.1 - 0.18 12.2 1.0 1.2 9.5 0.1 2.0 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF202 PF02656.10 AIF83779.1 - 0.22 11.7 3.8 0.66 10.2 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF998 PF06197.8 AIF83779.1 - 1.5 8.1 7.1 1.4 8.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Pyridox_oxidase PF01243.15 AIF83780.1 - 3.9e-20 71.6 0.0 5.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF83780.1 - 5.5e-14 52.2 0.1 6.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MtrA PF04208.9 AIF83781.1 - 3e-28 98.4 0.6 3.3e-28 98.3 0.4 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A dUTPase_2 PF08761.6 AIF83782.1 - 8.7e-20 71.4 2.8 6.9e-14 52.2 0.2 2.0 1 1 1 2 2 2 2 dUTPase DUF550 PF04447.7 AIF83782.1 - 0.00089 18.8 0.6 0.0017 17.9 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF550) PRA-PH PF01503.12 AIF83782.1 - 0.089 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase OMS28_porin PF03532.8 AIF83783.1 - 0.00052 19.1 0.1 0.0008 18.5 0.1 1.3 1 0 0 1 1 1 1 OMS28 porin Glycos_transf_2 PF00535.21 AIF83784.1 - 5.8e-36 123.7 0.0 9.9e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.9 AIF83784.1 - 2.7e-20 72.4 11.7 3.5e-19 68.8 8.8 2.0 1 1 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.1 AIF83784.1 - 7.1e-16 58.6 0.0 1.2e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.2 AIF83784.1 - 8.7e-07 29.1 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_2 PF10111.4 AIF83784.1 - 0.00088 18.4 0.1 0.0029 16.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AIF83784.1 - 0.0014 17.9 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Rad51 PF08423.6 AIF83785.1 - 5.3e-31 107.4 0.1 5.8e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AIF83785.1 - 1.8e-12 47.0 0.2 3.4e-12 46.1 0.2 1.4 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 AIF83785.1 - 2.6e-09 36.5 0.0 2.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AIF83785.1 - 1.6e-07 30.7 1.1 6.7e-06 25.3 0.7 2.1 1 1 0 1 1 1 1 KaiC AAA_10 PF12846.2 AIF83785.1 - 6.4e-05 22.5 0.0 7.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain CbiA PF01656.18 AIF83785.1 - 0.00084 18.8 0.0 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 AIF83785.1 - 0.0024 18.0 0.1 0.0079 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 AIF83785.1 - 0.0058 15.2 0.1 0.011 14.4 0.0 1.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 AIF83785.1 - 0.0099 15.6 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase IstB_IS21 PF01695.12 AIF83785.1 - 0.015 14.6 0.1 0.04 13.3 0.1 1.7 1 1 1 2 2 2 0 IstB-like ATP binding protein Zot PF05707.7 AIF83785.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 AIF83785.1 - 0.027 14.7 0.1 0.045 14.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 AIF83785.1 - 0.048 13.8 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 AIF83785.1 - 0.051 13.1 0.2 0.16 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 AIF83785.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 AIF83785.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AIF83785.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 NACHT domain ICAP-1_inte_bdg PF10480.4 AIF83785.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein PAXNEB PF05625.6 AIF83785.1 - 0.19 10.5 0.6 0.27 10.0 0.4 1.2 1 0 0 1 1 1 0 PAXNEB protein LSM PF01423.17 AIF83786.1 - 2.6e-17 62.1 0.8 2.9e-17 61.9 0.6 1.0 1 0 0 1 1 1 1 LSM domain DUF1161 PF06649.7 AIF83786.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) S-AdoMet_synt_C PF02773.11 AIF83787.1 - 1e-69 232.5 0.3 1.8e-69 231.8 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AIF83787.1 - 4.2e-50 168.6 0.0 1.3e-49 167.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AIF83787.1 - 3.9e-43 145.7 1.8 5.1e-43 145.3 0.0 2.1 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, N-terminal domain adh_short PF00106.20 AIF83788.1 - 8.7e-31 107.0 0.1 1.5e-30 106.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIF83788.1 - 1.3e-27 97.0 0.4 1.6e-27 96.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF83788.1 - 4.8e-14 52.4 0.1 7.8e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AIF83788.1 - 1.1e-05 25.5 0.4 1.8e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 AIF83788.1 - 0.00014 21.3 0.1 0.00038 19.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 AIF83788.1 - 0.00026 20.0 0.0 0.00061 18.8 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 AIF83788.1 - 0.0072 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 AIF83788.1 - 0.049 14.0 0.4 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 AIF83788.1 - 0.05 12.6 0.1 0.12 11.4 0.0 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CbiD PF01888.12 AIF83789.1 - 3.6e-83 278.5 5.6 5.3e-83 277.9 3.9 1.2 1 0 0 1 1 1 1 CbiD HTH_AsnC-type PF13404.1 AIF83790.1 - 1.2e-13 50.2 0.1 3.5e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AIF83790.1 - 2.5e-11 42.8 0.1 4.4e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Arc_trans_TRASH PF08394.5 AIF83790.1 - 7.4e-06 26.0 3.0 1.5e-05 25.0 2.1 1.6 1 0 0 1 1 1 1 Archaeal TRASH domain TrmB PF01978.14 AIF83790.1 - 2.2e-05 24.0 0.1 3.8e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AIF83790.1 - 0.00038 20.0 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 AIF83790.1 - 0.0012 18.7 0.5 0.0021 17.9 0.4 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_9 PF08221.6 AIF83790.1 - 0.0076 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 AIF83790.1 - 0.0081 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 YkyA PF10368.4 AIF83790.1 - 0.0097 15.2 0.2 0.62 9.3 0.0 2.1 2 0 0 2 2 2 1 Putative cell-wall binding lipoprotein zf-FCS PF06467.9 AIF83790.1 - 0.017 14.7 4.8 0.042 13.4 3.3 1.7 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HTH_28 PF13518.1 AIF83790.1 - 0.046 13.7 0.6 0.12 12.3 0.0 2.0 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 AIF83790.1 - 0.05 13.0 0.1 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2089 PF09862.4 AIF83790.1 - 0.055 13.2 0.3 0.23 11.2 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2089) ATPase-cat_bd PF12156.3 AIF83790.1 - 0.086 13.3 1.5 0.22 12.0 1.0 1.7 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase FeoC PF09012.5 AIF83790.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator MarR_2 PF12802.2 AIF83790.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.2 AIF83790.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 AIF83790.1 - 0.16 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-H2C2_2 PF13465.1 AIF83790.1 - 4.5 7.7 7.3 12 6.3 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain PMT_2 PF13231.1 AIF83791.1 - 5.9e-14 52.2 13.1 5.9e-14 52.2 9.1 3.3 4 1 1 5 5 5 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 AIF83791.1 - 1.9e-13 50.3 11.9 1.9e-13 50.3 8.2 3.1 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.1 AIF83792.1 - 1.1e-13 51.3 14.7 1.1e-13 51.3 10.2 3.9 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Acyl_transf_3 PF01757.17 AIF83792.1 - 4.9 5.8 42.4 9.1 5.0 6.1 3.3 1 1 2 3 3 3 0 Acyltransferase family CbiG_N PF11760.3 AIF83793.1 - 4.6e-32 109.5 0.2 4.6e-32 109.5 0.1 1.8 2 0 0 2 2 2 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.11 AIF83793.1 - 3.5e-30 104.7 0.0 7e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.3 AIF83793.1 - 1.5e-13 50.7 0.0 9.2e-13 48.2 0.0 2.3 2 0 0 2 2 2 1 Cobalamin biosynthesis central region CbiC PF02570.10 AIF83794.1 - 3.6e-72 241.9 0.1 8.4e-72 240.7 0.1 1.6 1 0 0 1 1 1 1 Precorrin-8X methylmutase CbiX PF01903.12 AIF83794.1 - 2.6e-35 120.7 0.1 1.5e-16 60.4 0.1 2.4 2 0 0 2 2 2 2 CbiX CbiK PF06180.6 AIF83794.1 - 5.5e-11 42.0 0.1 8.2e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.14 AIF83794.1 - 0.00044 19.3 0.0 0.025 13.5 0.0 2.3 1 1 1 2 2 2 2 Ferrochelatase GATase_3 PF07685.9 AIF83795.1 - 4.3e-31 107.6 0.1 8.2e-31 106.7 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.18 AIF83795.1 - 3.7e-23 81.9 0.1 6.3e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 AIF83795.1 - 1.9e-14 53.7 3.5 6.5e-10 38.9 0.0 2.9 1 1 2 3 3 3 2 AAA domain SNO PF01174.14 AIF83795.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family AAA_17 PF13207.1 AIF83795.1 - 0.021 15.6 0.0 0.25 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_31 PF13614.1 AIF83795.1 - 0.098 12.5 0.3 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain CTP_synth_N PF06418.9 AIF83795.1 - 0.14 11.2 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 CTP synthase N-terminus Peptidase_C26 PF07722.8 AIF83795.1 - 0.17 11.3 0.0 0.66 9.3 0.0 2.0 1 1 0 1 1 1 0 Peptidase C26 bPH_3 PF14470.1 AIF83796.1 - 5.6e-10 39.3 0.0 8.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain SHOCT PF09851.4 AIF83796.1 - 0.00076 18.8 1.7 0.0019 17.6 1.2 1.7 1 0 0 1 1 1 1 Short C-terminal domain CobA_CobO_BtuR PF02572.10 AIF83797.1 - 1.5e-60 203.7 0.5 1.8e-60 203.5 0.4 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP IstB_IS21 PF01695.12 AIF83797.1 - 0.0012 18.2 0.6 0.68 9.3 0.1 2.1 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 AIF83797.1 - 0.088 12.5 1.1 0.19 11.5 0.3 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 AIF83797.1 - 0.13 12.4 0.6 0.37 10.9 0.4 1.7 1 1 0 1 1 1 0 AAA domain EIF_2_alpha PF07541.7 AIF83798.1 - 3.7e-22 78.2 2.6 4.2e-22 78.0 0.2 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AIF83798.1 - 1e-12 47.9 0.3 3.5e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 S1 RNA binding domain Nop10p PF04135.7 AIF83799.1 - 1.4e-22 79.1 3.3 1.6e-22 79.0 2.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family RecR PF02132.10 AIF83799.1 - 0.0049 16.2 1.2 0.0063 15.9 0.8 1.2 1 0 0 1 1 1 1 RecR protein DZR PF12773.2 AIF83799.1 - 0.024 14.4 1.6 0.032 14.0 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.8 AIF83799.1 - 0.033 11.8 0.4 0.031 11.9 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 NOB1_Zn_bind PF08772.6 AIF83799.1 - 0.085 12.7 0.2 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C4_Topoisom PF01396.14 AIF83799.1 - 0.12 11.9 1.3 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF1272 PF06906.6 AIF83799.1 - 0.13 12.1 2.4 0.18 11.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.1 AIF83799.1 - 0.21 11.3 1.8 0.28 10.8 1.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 AIF83799.1 - 0.34 10.1 7.7 2.9 7.2 0.7 2.2 1 1 1 2 2 2 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 AIF83799.1 - 0.41 10.3 0.1 0.41 10.3 0.1 2.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain DUF35_N PF12172.3 AIF83799.1 - 0.61 10.0 2.5 1.9 8.4 1.7 1.9 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-HIT PF04438.11 AIF83799.1 - 0.66 9.6 5.7 1.6 8.4 3.9 1.6 1 1 0 1 1 1 0 HIT zinc finger TFIIS_C PF01096.13 AIF83799.1 - 1.2 8.8 4.0 6 6.5 0.4 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.1 AIF83799.1 - 1.7 8.2 5.9 4.8 6.8 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-tcix PF14952.1 AIF83799.1 - 1.9 7.8 9.1 21 4.5 6.3 2.0 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Zn-ribbon_8 PF09723.5 AIF83799.1 - 4 7.4 5.9 6 6.9 0.6 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 AIF83799.1 - 4.9 6.9 5.6 15 5.3 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NAD_binding_8 PF13450.1 AIF83800.1 - 0.00053 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AIF83800.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 AIF83800.1 - 0.0027 16.3 0.0 0.075 11.6 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 AIF83800.1 - 0.016 15.1 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AIF83800.1 - 0.071 12.0 0.0 0.26 10.1 0.0 1.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AIF83800.1 - 0.2 10.6 0.0 0.38 9.7 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain 4HBT PF03061.17 AIF83801.1 - 7.9e-18 64.3 0.3 1.1e-17 63.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 AIF83801.1 - 0.0036 16.6 0.1 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain DUF4442 PF14539.1 AIF83801.1 - 0.049 13.6 1.0 0.41 10.6 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) BTV_NS2 PF04514.7 AIF83802.1 - 0.07 12.0 3.2 0.075 11.9 2.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Paf1 PF03985.8 AIF83802.1 - 0.14 10.9 2.8 0.15 10.7 2.0 1.1 1 0 0 1 1 1 0 Paf1 IFT57 PF10498.4 AIF83802.1 - 0.14 10.8 1.5 0.15 10.7 1.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PEP_mutase PF13714.1 AIF83803.1 - 3.1e-59 200.0 0.0 3.6e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 AIF83803.1 - 4.9e-16 58.0 0.0 2.2e-14 52.5 0.0 2.5 1 1 1 2 2 2 2 Isocitrate lyase family Glyoxalase_2 PF12681.2 AIF83804.1 - 1.6e-14 54.4 0.0 1.9e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF83804.1 - 1.3e-10 41.2 0.0 2.2e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2757 PF10955.3 AIF83805.1 - 0.0011 19.0 0.1 0.0016 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) TFIIS_C PF01096.13 AIF83805.1 - 0.0041 16.7 0.9 0.079 12.6 0.2 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF3268 PF11672.3 AIF83805.1 - 0.044 13.8 0.2 0.046 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) Zn_Tnp_IS1595 PF12760.2 AIF83805.1 - 0.057 13.2 1.8 0.11 12.3 1.2 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 AIF83805.1 - 0.066 13.2 0.1 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DNA_ligase_ZBD PF03119.11 AIF83805.1 - 0.073 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain UPF0547 PF10571.4 AIF83805.1 - 0.09 12.4 0.8 0.18 11.5 0.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.1 AIF83805.1 - 0.095 13.0 0.4 0.13 12.6 0.3 1.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF3797 PF12677.2 AIF83805.1 - 0.12 12.0 0.2 12 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DUF329 PF03884.9 AIF83805.1 - 0.83 9.2 3.1 1.6 8.3 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zf-H2C2_2 PF13465.1 AIF83805.1 - 1.1 9.6 6.1 1.1 9.6 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-IS66 PF13005.2 AIF83805.1 - 2.8 8.0 6.6 6.2 6.8 0.2 2.3 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 Rubredoxin PF00301.15 AIF83805.1 - 4.1 7.3 5.2 72 3.3 0.3 2.4 1 1 1 2 2 2 0 Rubredoxin TF_Zn_Ribbon PF08271.7 AIF83807.1 - 0.006 15.8 0.3 0.78 9.1 0.1 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding Elf1 PF05129.8 AIF83807.1 - 0.0096 15.6 1.3 2.4 7.9 0.1 2.1 1 1 1 2 2 2 2 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 AIF83807.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_5 PF13719.1 AIF83807.1 - 0.013 15.0 0.2 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 AIF83807.1 - 0.017 14.7 0.2 0.024 14.2 0.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AIF83807.1 - 0.019 14.6 0.7 0.031 14.0 0.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_4 PF13717.1 AIF83807.1 - 0.024 14.3 0.2 3 7.6 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 AIF83807.1 - 0.074 13.4 0.4 3.7 8.1 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Rubredoxin PF00301.15 AIF83807.1 - 0.075 12.9 0.1 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin Zn-ribbon_8 PF09723.5 AIF83807.1 - 0.42 10.6 2.1 1.7 8.6 1.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 AIF83807.1 - 1 9.8 3.4 28 5.2 2.4 2.3 1 1 0 1 1 1 0 Zinc-finger double domain HTH_24 PF13412.1 AIF83808.1 - 3.1e-08 32.8 0.1 5.1e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF83808.1 - 0.0001 21.7 0.5 0.00018 20.9 0.4 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.2 AIF83808.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF83808.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.17 AIF83808.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.5 AIF83808.1 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain AsnC_trans_reg PF01037.16 AIF83808.1 - 0.0026 17.4 0.1 0.0056 16.3 0.0 1.6 2 0 0 2 2 2 1 AsnC family TrmB PF01978.14 AIF83808.1 - 0.0055 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 AIF83808.1 - 0.031 14.2 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.2 AIF83808.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Sigma70_r4_2 PF08281.7 AIF83808.1 - 0.068 12.6 0.1 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.7 AIF83808.1 - 0.09 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 HTH domain AMMECR1 PF01871.12 AIF83809.1 - 3.5e-49 166.2 0.0 4.2e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Glyco_trans_1_3 PF13528.1 AIF83810.1 - 6.3e-27 94.6 0.0 8.2e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 AIF83810.1 - 1.6e-11 44.1 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 AIF83810.1 - 9.3e-08 31.0 0.0 2.7e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glycos_transf_1 PF00534.15 AIF83810.1 - 0.00044 19.7 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 THUMP PF02926.12 AIF83811.1 - 0.027 14.3 0.6 0.087 12.7 0.1 2.0 2 1 1 3 3 3 0 THUMP domain FixQ PF05545.6 AIF83812.1 - 0.017 14.7 2.0 0.026 14.1 1.4 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF347 PF03988.7 AIF83812.1 - 0.032 14.1 1.1 0.049 13.5 0.7 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) ABC2_membrane_4 PF12730.2 AIF83812.1 - 0.12 11.5 2.6 0.13 11.4 1.8 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein PRRSV_2b PF07069.6 AIF83812.1 - 0.14 12.4 0.7 0.19 12.0 0.5 1.1 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b Ribosomal_S13_N PF08069.7 AIF83814.1 - 3.8e-24 84.2 0.4 9.2e-24 83.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AIF83814.1 - 1.4e-16 60.0 0.2 2.6e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 AIF83814.1 - 0.035 13.8 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTHP PF11534.3 AIF83814.1 - 0.11 12.5 0.1 0.58 10.2 0.0 2.2 1 1 2 3 3 3 0 Hexameric tyrosine-coordinated heme protein (HTHP) DDE_Tnp_IS1 PF03400.8 AIF83814.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 IS1 transposase DHH PF01368.15 AIF83815.1 - 1.4e-10 40.9 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.14 AIF83815.1 - 2.6e-07 30.2 0.0 7.9e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 DHHA1 domain Pcc1 PF09341.5 AIF83816.1 - 8.9e-05 22.4 0.1 0.00015 21.7 0.0 1.4 1 1 0 1 1 1 1 Transcription factor Pcc1 tRNA-synt_2b PF00587.20 AIF83817.1 - 1.3e-34 119.3 0.0 2.1e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AIF83817.1 - 1.2e-23 83.2 9.3 2.1e-23 82.3 6.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 AIF83817.1 - 0.12 12.0 5.5 0.23 11.1 3.8 1.4 1 0 0 1 1 1 0 Mnd1 family FimP PF09766.4 AIF83817.1 - 0.13 11.2 4.2 0.21 10.5 2.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein APG6 PF04111.7 AIF83817.1 - 8.7 5.2 9.5 17 4.3 4.7 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Ribosomal_S3Ae PF01015.13 AIF83818.1 - 3.8e-46 156.8 1.0 4.5e-46 156.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family RNA_binding PF01877.12 AIF83819.1 - 4.1e-20 71.9 0.0 5.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 RNA binding RNase_P_p30 PF01876.11 AIF83820.1 - 4.2e-05 22.8 0.0 5.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 RNase_P_Rpp14 PF01900.14 AIF83821.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Radical_SAM PF04055.16 AIF83822.1 - 5.8e-18 65.6 0.1 4.3e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily NRPS PF08415.5 AIF83822.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Nonribosomal peptide synthase Polysacc_deac_1 PF01522.16 AIF83823.1 - 8.6e-14 51.2 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 AIF83823.1 - 0.0015 17.5 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 N6_N4_Mtase PF01555.13 AIF83823.1 - 0.023 14.2 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 DNA methylase PhoU_div PF01865.11 AIF83824.1 - 7.5e-16 57.9 5.3 9e-16 57.6 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 HAP1_N PF04849.8 AIF83824.1 - 0.0034 16.3 1.2 0.0034 16.3 0.8 1.7 2 0 0 2 2 2 1 HAP1 N-terminal conserved region Reo_sigmaC PF04582.7 AIF83824.1 - 0.0047 16.1 0.8 0.28 10.3 0.1 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein PhoU PF01895.14 AIF83824.1 - 0.0073 16.7 6.0 0.42 11.0 1.5 2.5 2 1 0 2 2 2 2 PhoU domain ApoLp-III PF07464.6 AIF83824.1 - 0.0076 16.2 1.9 0.23 11.4 0.2 2.3 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) TraD PF06412.6 AIF83824.1 - 0.052 13.1 0.2 0.34 10.5 0.1 2.2 2 0 0 2 2 2 0 Conjugal transfer protein TraD DUF3342 PF11822.3 AIF83824.1 - 0.15 11.1 2.2 0.31 10.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) Bacillus_HBL PF05791.6 AIF83824.1 - 0.17 11.2 1.6 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin_2 PF14523.1 AIF83824.1 - 0.2 11.7 2.5 0.17 11.9 0.6 1.7 2 0 0 2 2 2 0 Syntaxin-like protein Cluap1 PF10234.4 AIF83824.1 - 0.35 10.0 3.3 0.48 9.5 1.1 1.8 2 0 0 2 2 2 0 Clusterin-associated protein-1 IncA PF04156.9 AIF83824.1 - 0.85 9.1 5.0 0.22 11.1 1.3 1.6 2 0 0 2 2 2 0 IncA protein ATG16 PF08614.6 AIF83824.1 - 2.8 7.7 9.0 5.5 6.7 0.1 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) tRNA_int_endo PF01974.12 AIF83825.1 - 5e-26 90.3 0.1 9.5e-26 89.4 0.0 1.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AIF83825.1 - 1.7e-16 59.5 0.0 2.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain HIRAN PF08797.6 AIF83826.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.7 1 1 0 1 1 1 0 HIRAN domain HIT PF01230.18 AIF83828.1 - 5.4e-24 84.5 0.9 5.5e-24 84.5 0.1 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 AIF83828.1 - 1.8e-14 53.9 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AIF83828.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF915 PF06028.6 AIF83829.1 - 0.041 12.9 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ApoA-II PF04711.8 AIF83829.1 - 0.044 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) DUF2267 PF10025.4 AIF83829.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Bac_DNA_binding PF00216.16 AIF83829.1 - 0.13 12.2 0.0 0.83 9.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial DNA-binding protein Gly-zipper_OmpA PF13436.1 AIF83829.1 - 0.16 11.6 11.8 0.37 10.4 2.5 2.4 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF937 PF06078.6 AIF83829.1 - 1.8 8.7 20.6 1.8 8.8 4.2 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF937) Elf1 PF05129.8 AIF83830.1 - 0.0028 17.3 0.2 0.0032 17.1 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 AIF83830.1 - 0.039 13.5 2.8 0.53 9.9 1.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIF83830.1 - 0.053 13.1 0.2 0.066 12.8 0.1 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Rubredoxin PF00301.15 AIF83830.1 - 0.059 13.2 0.2 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_4 PF13717.1 AIF83830.1 - 0.061 13.0 2.1 1.8 8.3 1.6 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AIF83830.1 - 0.067 13.1 1.2 0.1 12.6 0.8 1.3 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 AIF83830.1 - 0.28 11.5 1.5 1.4 9.3 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 AIF83830.1 - 2.1 8.8 4.0 21 5.7 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.7 AIF83830.1 - 3.4 7.0 5.8 2.3 7.5 0.3 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding Phage_integrase PF00589.17 AIF83831.1 - 3.5e-16 59.3 1.2 9.3e-16 57.9 0.8 1.8 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 AIF83831.1 - 0.014 15.4 0.3 0.98 9.6 0.0 2.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3192 PF11399.3 AIF83831.1 - 0.19 11.6 1.1 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) RRN7 PF11781.3 AIF83832.1 - 0.01 15.3 0.1 0.01 15.3 0.1 5.3 7 0 0 7 7 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ecl1 PF12855.2 AIF83832.1 - 0.016 14.5 2.7 0.016 14.5 1.8 4.7 4 1 1 5 5 5 0 Life-span regulatory factor HNH_5 PF14279.1 AIF83832.1 - 0.025 14.5 12.3 0.25 11.3 0.5 4.6 2 1 2 4 4 4 0 HNH endonuclease zf-HIT PF04438.11 AIF83832.1 - 0.067 12.8 0.9 0.067 12.8 0.6 6.0 5 2 0 5 5 5 0 HIT zinc finger zinc_ribbon_5 PF13719.1 AIF83832.1 - 0.72 9.4 24.6 0.58 9.7 0.9 5.5 5 0 0 5 5 5 0 zinc-ribbon domain zf-MYND PF01753.13 AIF83832.1 - 1.8 8.4 42.5 0.062 13.1 2.2 5.3 3 2 1 4 4 4 0 MYND finger zinc_ribbon_4 PF13717.1 AIF83832.1 - 2.3 8.0 24.8 0.72 9.5 1.2 5.4 5 0 0 5 5 5 0 zinc-ribbon domain DUF2116 PF09889.4 AIF83832.1 - 3.2 7.6 30.9 0.11 12.3 1.2 5.2 3 2 2 5 5 5 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DNA_RNApol_7kD PF03604.8 AIF83832.1 - 5 6.6 18.5 2.4 7.7 0.6 4.7 4 1 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit DDRGK PF09756.4 AIF83833.1 - 0.18 11.1 9.9 0.22 10.9 6.8 1.1 1 0 0 1 1 1 0 DDRGK domain Nop53 PF07767.6 AIF83833.1 - 0.26 10.2 16.5 0.28 10.1 11.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Acyl-CoA_dh_2 PF08028.6 AIF83833.1 - 0.98 9.6 7.2 1.3 9.3 5.0 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF4355 PF14265.1 AIF83833.1 - 3 7.8 18.1 3.7 7.5 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) APG6 PF04111.7 AIF83833.1 - 3.4 6.6 11.0 3.4 6.6 7.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TAF8_C PF10406.4 AIF83833.1 - 7.3 6.7 5.9 2.2 8.4 0.9 2.2 2 1 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Prim-Pol PF09250.6 AIF83835.1 - 1.4e-15 57.6 0.0 3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal D5_N PF08706.6 AIF83835.1 - 3e-11 43.6 1.1 3e-11 43.6 0.8 2.1 2 0 0 2 2 2 1 D5 N terminal like Pox_D5 PF03288.11 AIF83835.1 - 0.013 15.7 0.0 0.047 13.9 0.0 1.9 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF3702 PF12486.3 AIF83835.1 - 0.015 14.9 0.6 0.56 9.8 0.3 2.5 2 0 0 2 2 2 0 ImpA domain protein RFX_DNA_binding PF02257.10 AIF83835.1 - 0.1 12.7 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 RFX DNA-binding domain zf-ribbon_3 PF13248.1 AIF83837.1 - 0.004 16.3 0.4 0.3 10.3 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF83837.1 - 0.0043 16.6 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain HypA PF01155.14 AIF83837.1 - 0.012 15.3 0.2 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 AIF83837.1 - 0.014 15.0 0.2 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF1360 PF07098.6 AIF83837.1 - 0.027 14.1 0.0 0.029 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) DNA_RNApol_7kD PF03604.8 AIF83837.1 - 0.049 13.1 1.6 1.4 8.4 0.3 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.1 AIF83837.1 - 0.051 13.0 2.4 0.46 10.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Ogr_Delta PF04606.7 AIF83837.1 - 0.055 13.1 1.8 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.2 AIF83837.1 - 0.07 12.9 2.0 0.31 10.9 1.3 1.9 1 1 0 1 1 1 0 Double zinc ribbon Cys_rich_CPXG PF14255.1 AIF83837.1 - 0.076 12.8 0.3 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-HYPF PF07503.7 AIF83837.1 - 0.16 11.4 0.1 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 HypF finger zf-H2C2_5 PF13909.1 AIF83837.1 - 0.22 11.8 2.4 12 6.4 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain UPF0547 PF10571.4 AIF83837.1 - 0.36 10.5 6.9 0.95 9.2 1.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CpXC PF14353.1 AIF83837.1 - 0.46 10.4 0.1 0.46 10.4 0.1 1.8 1 1 1 2 2 2 0 CpXC protein Antitoxin-MazE PF04014.13 AIF83838.1 - 5.5e-07 29.1 0.1 9.2e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Antidote-toxin recognition MazE HupE_UreJ PF04955.7 AIF83839.1 - 0.0075 15.5 0.4 0.0077 15.5 0.3 1.0 1 0 0 1 1 1 1 HupE / UreJ protein DUF2083 PF09856.4 AIF83840.1 - 0.073 12.7 0.1 0.073 12.7 0.1 1.0 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) DUF904 PF06005.7 AIF83841.1 - 0.066 13.5 1.1 4.1 7.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF2080 PF09853.4 AIF83842.1 - 0.0044 16.7 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative transposon-encoded protein (DUF2080) Phage_integrase PF00589.17 AIF83843.1 - 7.4e-14 51.7 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 AIF83843.1 - 0.027 14.6 0.0 0.3 11.2 0.0 2.7 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain ILVD_EDD PF00920.16 AIF83844.1 - 7.7e-219 727.4 10.8 8.8e-219 727.2 7.5 1.0 1 0 0 1 1 1 1 Dehydratase family Chorismate_bind PF00425.13 AIF83845.1 - 1.3e-94 316.3 0.0 9.1e-94 313.5 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 AIF83845.1 - 4.8e-25 88.1 0.0 2.2e-22 79.5 0.0 2.4 2 0 0 2 2 2 2 Anthranilate synthase component I, N terminal region MerR PF00376.18 AIF83845.1 - 0.046 13.2 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 MerR family regulatory protein PALP PF00291.20 AIF83846.1 - 1.2e-45 156.1 0.0 1.6e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PK_C PF02887.11 AIF83846.1 - 0.014 14.8 0.9 0.58 9.7 0.2 2.6 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Ehrlichia_rpt PF09528.5 AIF83847.1 - 0.024 12.7 0.1 0.024 12.7 0.1 1.0 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Snf7 PF03357.16 AIF83847.1 - 0.025 13.9 2.7 0.035 13.5 1.3 1.6 1 1 1 2 2 2 0 Snf7 EST1_DNA_bind PF10373.4 AIF83847.1 - 0.062 12.5 0.2 0.063 12.4 0.1 1.0 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Acetyltransf_1 PF00583.19 AIF83848.1 - 6.2e-13 48.5 0.3 8.9e-13 48.0 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AIF83848.1 - 5.6e-11 42.4 0.1 1.1e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AIF83848.1 - 2.7e-09 37.1 0.0 3.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AIF83848.1 - 1.8e-08 34.4 0.0 2.2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AIF83848.1 - 2.6e-06 27.3 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AIF83848.1 - 2.7e-06 27.6 0.0 3.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AIF83848.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Snf7 PF03357.16 AIF83849.1 - 0.07 12.5 5.7 0.13 11.6 4.0 1.5 1 1 0 1 1 1 0 Snf7 Aminotran_1_2 PF00155.16 AIF83851.1 - 6e-57 193.2 0.1 6.9e-57 193.0 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AIF83851.1 - 0.0018 16.6 0.0 0.0026 16.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AIF83851.1 - 0.0034 16.1 0.2 0.0053 15.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIF83851.1 - 0.018 14.1 0.2 0.26 10.4 0.1 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase BATS PF06968.8 AIF83852.1 - 6.6e-23 80.3 0.0 1.9e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 AIF83852.1 - 6e-14 52.5 0.4 1.2e-13 51.6 0.3 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DeoC PF01791.4 AIF83852.1 - 0.023 13.9 0.0 3 7.0 0.0 2.8 3 0 0 3 3 3 0 DeoC/LacD family aldolase Fibrillarin_2 PF10113.4 AIF83852.1 - 0.045 12.1 0.0 0.065 11.5 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein His_biosynth PF00977.16 AIF83852.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Opiods_neuropep PF01160.13 AIF83852.1 - 0.81 9.4 3.7 6 6.7 0.3 2.4 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide AraC_binding PF02311.14 AIF83853.1 - 3.5e-07 29.9 0.0 4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.6 AIF83853.1 - 5.1e-07 29.0 0.0 6.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.7 AIF83853.1 - 0.00027 20.5 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.2 AIF83853.1 - 0.0006 19.4 0.0 0.0006 19.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 AIF83853.1 - 0.0018 17.5 0.1 0.0026 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Rep_1 PF01446.12 AIF83855.1 - 2.3e-05 23.8 0.5 3.6e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Replication protein Zn_Tnp_IS1595 PF12760.2 AIF83856.1 - 0.0006 19.5 17.0 0.018 14.8 2.7 4.0 4 0 0 4 4 4 2 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIF83856.1 - 0.00078 19.0 2.3 0.00078 19.0 1.6 3.7 2 1 2 4 4 4 2 Putative transposase DNA-binding domain DZR PF12773.2 AIF83856.1 - 0.001 18.8 23.1 0.022 14.5 5.2 3.7 1 1 2 3 3 3 1 Double zinc ribbon TF_Zn_Ribbon PF08271.7 AIF83856.1 - 0.0013 18.0 7.4 0.03 13.6 2.0 4.7 4 1 1 5 5 5 3 TFIIB zinc-binding DUF2296 PF10058.4 AIF83856.1 - 0.0016 18.1 3.3 0.012 15.3 0.8 4.1 5 0 0 5 5 4 2 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 AIF83856.1 - 0.0027 17.6 23.0 0.0075 16.2 2.1 4.9 4 1 0 4 4 4 1 Zinc ribbon domain DUF3795 PF12675.2 AIF83856.1 - 0.0056 16.8 14.6 0.18 11.9 1.6 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3795) Ribosomal_S27e PF01667.12 AIF83856.1 - 0.01 15.3 1.0 0.01 15.3 0.7 3.7 4 1 0 4 4 4 0 Ribosomal protein S27 Jiv90 PF14901.1 AIF83856.1 - 0.016 15.1 3.4 0.016 15.1 2.3 2.4 3 0 0 3 3 3 0 Cleavage inducing molecular chaperone DNA_RNApol_7kD PF03604.8 AIF83856.1 - 0.055 12.9 23.1 0.15 11.5 2.1 4.5 4 1 1 5 5 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_3 PF14369.1 AIF83856.1 - 0.23 11.4 18.0 0.13 12.2 1.4 4.2 3 1 1 4 4 4 0 zinc-finger Elf1 PF05129.8 AIF83856.1 - 0.27 10.9 18.6 0.76 9.5 1.5 3.7 2 1 2 4 4 4 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 AIF83856.1 - 0.28 10.4 23.3 0.29 10.4 3.2 5.1 4 1 1 5 5 5 0 zinc-ribbon domain IBR PF01485.16 AIF83856.1 - 0.48 10.3 22.9 0.4 10.6 1.6 3.6 2 1 2 4 4 4 0 IBR domain zf-MIZ PF02891.15 AIF83856.1 - 0.5 9.9 8.3 6.4 6.3 1.9 2.7 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger DUF4109 PF13397.1 AIF83856.1 - 0.88 9.9 4.1 6.1 7.2 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4109) zf-CHY PF05495.7 AIF83856.1 - 0.89 9.7 20.1 0.059 13.5 5.0 3.7 2 1 2 5 5 5 0 CHY zinc finger eIF-5_eIF-2B PF01873.12 AIF83856.1 - 0.92 9.1 8.7 0.069 12.8 1.0 2.4 2 1 1 3 3 3 0 Domain found in IF2B/IF5 HypA PF01155.14 AIF83856.1 - 0.95 9.1 20.8 0.15 11.7 3.1 3.3 2 1 2 4 4 3 0 Hydrogenase expression/synthesis hypA family DUF3268 PF11672.3 AIF83856.1 - 1.3 9.1 7.5 0.36 10.9 0.9 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3268) Lar_restr_allev PF14354.1 AIF83856.1 - 2.1 8.6 19.0 0.21 11.9 0.5 3.8 1 1 2 3 3 3 0 Restriction alleviation protein Lar zf-trcl PF13451.1 AIF83856.1 - 2.7 7.7 21.3 3.7 7.2 0.1 5.3 5 1 0 5 5 5 0 Probable zinc-binding domain Cytochrome_C554 PF13435.1 AIF83856.1 - 6.2 6.8 19.3 0.9 9.6 10.4 1.9 2 1 0 2 2 2 0 Cytochrome c554 and c-prime YjgP_YjgQ PF03739.9 AIF83857.1 - 0.52 8.9 3.7 0.61 8.7 2.6 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF485 PF04341.7 AIF83858.1 - 0.13 11.9 0.6 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ELYS PF13934.1 AIF83859.1 - 0.016 14.9 0.1 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex assembly Arch_ATPase PF01637.13 AIF83860.1 - 0.00032 20.4 0.0 0.001 18.8 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 AIF83860.1 - 0.0012 17.7 0.1 0.0026 16.6 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 AIF83860.1 - 0.0035 16.7 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIF83860.1 - 0.0088 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 AIF83860.1 - 0.013 15.6 0.0 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PPK2 PF03976.9 AIF83860.1 - 0.022 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) DUF815 PF05673.8 AIF83860.1 - 0.038 12.9 0.0 0.066 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) EIID-AGA PF03613.9 AIF83860.1 - 0.041 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component AAA_24 PF13479.1 AIF83860.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIF83860.1 - 0.13 11.8 0.1 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Activator_LAG-3 PF11498.3 AIF83861.1 - 0.0074 15.0 0.1 0.0074 15.0 0.1 1.0 1 0 0 1 1 1 1 Transcriptional activator LAG-3 CD20 PF04103.10 AIF83861.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 CD20-like family MFS_1 PF07690.11 AIF83862.1 - 0.025 13.2 2.2 0.025 13.2 1.5 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3333 PF11812.3 AIF83862.1 - 0.055 13.4 0.2 0.055 13.4 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3333) TrbC PF04956.8 AIF83862.1 - 0.094 12.7 2.0 0.15 12.0 1.4 1.5 1 1 0 1 1 1 0 TrbC/VIRB2 family PsbI PF02532.9 AIF83862.1 - 0.16 11.5 0.5 0.16 11.5 0.3 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Sec-ASP3 PF15432.1 AIF83866.1 - 0.088 12.7 0.1 0.86 9.5 0.0 2.2 2 1 0 2 2 2 0 Accessory Sec secretory system ASP3 PP1 PF07430.6 AIF83867.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 DUF4064 PF13273.1 AIF83868.1 - 0.016 15.3 3.0 0.026 14.6 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) UNC-93 PF05978.11 AIF83868.1 - 0.068 12.6 0.3 2.7 7.4 0.1 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Cyd_oper_YbgE PF09600.5 AIF83868.1 - 0.27 11.4 3.7 0.2 11.8 0.3 2.0 1 1 1 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF485 PF04341.7 AIF83868.1 - 0.36 10.5 3.1 5.1 6.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 SKG6 PF08693.5 AIF83868.1 - 0.4 10.0 2.2 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Podoplanin PF05808.6 AIF83868.1 - 0.55 9.7 0.1 0.55 9.7 0.0 2.0 1 1 1 2 2 2 0 Podoplanin ABC2_membrane_4 PF12730.2 AIF83868.1 - 0.89 8.6 6.8 1.1 8.3 4.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MtrF PF09472.5 AIF83868.1 - 3.5 6.9 9.7 2 7.7 1.4 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Resolvase PF00239.16 AIF83869.1 - 2.4e-32 111.7 0.1 3.8e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.10 AIF83869.1 - 3.9e-07 29.8 0.1 8.1e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 AIF83869.1 - 2.4e-06 26.9 0.2 2.4e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 AIF83869.1 - 4e-06 26.2 0.4 1.1e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_30 PF13556.1 AIF83869.1 - 0.0003 20.2 0.1 0.0006 19.3 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.1 AIF83869.1 - 0.00043 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.8 AIF83869.1 - 0.00048 19.4 0.1 0.0023 17.3 0.0 2.2 2 1 1 3 3 3 1 CENP-B N-terminal DNA-binding domain HTH_8 PF02954.14 AIF83869.1 - 0.00073 19.0 1.4 0.00073 19.0 1.0 2.2 2 1 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_11 PF08279.7 AIF83869.1 - 0.0023 17.5 0.6 0.006 16.2 0.4 1.7 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.7 AIF83869.1 - 0.0037 16.8 0.2 0.0088 15.6 0.1 1.7 1 0 0 1 1 1 1 HTH DNA binding domain HTH_Tnp_1 PF01527.15 AIF83869.1 - 0.0063 16.4 0.6 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_22 PF13309.1 AIF83869.1 - 0.01 15.6 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 0 HTH domain TetR_N PF00440.18 AIF83869.1 - 0.013 15.1 0.1 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.1 AIF83869.1 - 0.017 14.2 0.0 0.043 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.1 AIF83869.1 - 0.039 14.0 1.2 0.28 11.3 0.1 2.5 1 1 1 2 2 2 0 Winged helix-turn helix TrmB PF01978.14 AIF83869.1 - 0.1 12.3 0.3 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB GerE PF00196.14 AIF83869.1 - 0.67 9.3 2.5 0.77 9.1 0.1 2.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family Aminotran_3 PF00202.16 AIF83870.1 - 3.3e-90 302.3 0.1 3.8e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FAD_binding_2 PF00890.19 AIF83870.1 - 0.016 14.1 0.0 0.054 12.3 0.0 1.9 3 0 0 3 3 3 0 FAD binding domain Beta_elim_lyase PF01212.16 AIF83870.1 - 0.1 11.7 0.0 0.25 10.4 0.0 1.6 2 1 0 2 2 2 0 Beta-eliminating lyase AAA_26 PF13500.1 AIF83871.1 - 1.5e-39 135.6 0.0 1.9e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 AIF83871.1 - 1.1e-11 44.5 0.5 2.4e-11 43.4 0.3 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_synth_N PF06418.9 AIF83871.1 - 0.00081 18.5 0.2 0.0077 15.3 0.1 2.1 2 0 0 2 2 2 1 CTP synthase N-terminus MobB PF03205.9 AIF83871.1 - 0.035 13.8 0.1 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.6 AIF83871.1 - 0.043 12.4 1.1 0.17 10.5 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) ArsA_ATPase PF02374.10 AIF83871.1 - 0.17 10.8 0.4 1.1 8.2 0.1 2.2 3 0 0 3 3 3 0 Anion-transporting ATPase Dicty_CAD PF05720.7 AIF83872.1 - 0.068 12.8 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Cell-cell adhesion domain DUF2975 PF11188.3 AIF83873.1 - 0.075 12.7 3.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) SLAC1 PF03595.12 AIF83873.1 - 0.16 10.5 4.3 0.21 10.2 3.0 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF3149 PF11346.3 AIF83873.1 - 0.43 10.1 0.0 0.43 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) NTP_transferase PF00483.18 AIF83874.1 - 4.5e-35 121.1 0.0 9e-35 120.1 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AIF83874.1 - 1.1e-07 32.0 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AIF83874.1 - 0.0081 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Bac_luciferase PF00296.15 AIF83875.1 - 2.3e-62 210.8 0.0 2.5e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Thiolase_C PF02803.13 AIF83876.1 - 8.7e-11 41.3 0.5 2.8e-10 39.6 0.3 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 AIF83876.1 - 2.4e-06 27.1 0.3 5.1e-05 22.8 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 AIF83876.1 - 0.00068 19.1 0.7 0.002 17.6 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AIF83876.1 - 0.0012 18.6 3.3 0.035 13.9 0.0 3.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 AIF83876.1 - 0.0024 16.9 1.7 0.0097 14.9 0.1 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain DUF35_N PF12172.3 AIF83877.1 - 6e-09 35.5 1.4 1.2e-08 34.6 1.0 1.5 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF35 PF01796.12 AIF83877.1 - 0.00081 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 DUF35 OB-fold domain DZR PF12773.2 AIF83877.1 - 0.056 13.2 1.7 0.11 12.3 1.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_C74 PF12387.3 AIF83877.1 - 0.11 11.5 0.4 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Zn_Tnp_IS1595 PF12760.2 AIF83877.1 - 1.4 8.8 7.1 0.64 9.8 0.8 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF83877.1 - 5 6.7 7.3 11 5.5 0.3 2.4 1 1 1 2 2 2 0 zinc-ribbon domain DUF3689 PF12463.3 AIF83878.1 - 0.051 12.3 0.1 0.066 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) DUF3107 PF11305.3 AIF83879.1 - 0.025 14.4 0.1 0.092 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) TrmB PF01978.14 AIF83879.1 - 0.097 12.3 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HATPase_c PF02518.21 AIF83880.1 - 8.8e-28 96.2 0.2 2.3e-27 94.9 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF83880.1 - 1.2e-10 41.2 0.8 4.1e-10 39.4 0.5 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PLDc_2 PF13091.1 AIF83880.1 - 0.00022 20.9 1.6 0.0089 15.7 0.1 3.1 3 1 0 3 3 3 1 PLD-like domain HATPase_c_5 PF14501.1 AIF83880.1 - 0.0011 18.6 0.1 0.004 16.8 0.0 1.9 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AIF83880.1 - 0.0013 18.4 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Regulator_TrmB PF11495.3 AIF83880.1 - 0.011 14.7 3.2 0.013 14.5 1.0 2.0 1 1 1 2 2 2 0 Archaeal transcriptional regulator TrmB HATPase_c_2 PF13581.1 AIF83880.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ribosomal_L6 PF00347.18 AIF83881.1 - 1.6e-18 66.9 9.5 2.7e-10 40.6 2.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S8 PF00410.14 AIF83882.1 - 5.5e-24 84.4 0.0 7.1e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.16 AIF83883.1 - 3.4e-16 58.3 5.1 4.5e-16 57.9 3.5 1.3 1 1 0 1 1 1 1 Ribosomal protein S14p/S29e zf-tcix PF14952.1 AIF83883.1 - 0.012 14.9 4.3 0.026 13.8 3.0 1.7 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DZR PF12773.2 AIF83883.1 - 0.11 12.3 0.4 0.17 11.7 0.3 1.4 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L5_C PF00673.16 AIF83884.1 - 1.6e-25 88.6 0.0 2.5e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AIF83884.1 - 3.2e-13 49.2 0.1 5.9e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S4e PF00900.15 AIF83885.1 - 1.2e-18 66.4 0.1 3.8e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 AIF83885.1 - 2e-11 43.5 0.8 3.3e-11 42.8 0.6 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 AIF83885.1 - 3.9e-06 26.2 0.1 8.6e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 AIF83885.1 - 0.008 15.8 0.1 0.036 13.7 0.0 2.2 1 0 0 1 1 1 1 KOW motif KOW PF00467.24 AIF83886.1 - 2.5e-05 23.8 5.9 7.6e-05 22.2 4.1 2.0 1 1 0 1 1 1 1 KOW motif HMG14_17 PF01101.13 AIF83886.1 - 0.051 14.2 16.3 0.11 13.1 9.4 2.2 2 0 0 2 2 2 0 HMG14 and HMG17 CMAS PF02353.15 AIF83886.1 - 0.053 12.6 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ribosomal_L14 PF00238.14 AIF83887.1 - 1.1e-33 115.6 0.0 1.2e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.15 AIF83888.1 - 1.4e-21 76.3 1.9 1.7e-21 76.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4411 PF14367.1 AIF83888.1 - 0.051 13.2 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) UPF0086 PF01868.11 AIF83889.1 - 1.3e-20 72.7 0.0 1.4e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.18 AIF83890.1 - 3.8e-15 55.2 4.1 4.6e-15 55.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein Ist1 PF03398.9 AIF83890.1 - 0.11 11.8 3.0 2.8 7.3 0.1 2.0 1 1 1 2 2 2 0 Regulator of Vps4 activity in the MVB pathway Vps51 PF08700.6 AIF83890.1 - 0.22 11.3 1.3 4.4 7.2 0.2 2.1 2 0 0 2 2 2 0 Vps51/Vps67 KH_2 PF07650.12 AIF83891.1 - 7.5e-14 51.0 0.0 1.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 KH domain Ribosomal_S3_C PF00189.15 AIF83891.1 - 4.6e-13 49.1 0.6 9.3e-13 48.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_1 PF00013.24 AIF83891.1 - 0.023 14.3 0.6 0.058 13.0 0.1 2.0 3 0 0 3 3 3 0 KH domain KH_3 PF13014.1 AIF83891.1 - 0.076 12.6 1.2 0.21 11.3 0.2 2.2 2 0 0 2 2 2 0 KH domain Ribosomal_L22 PF00237.14 AIF83892.1 - 7.6e-31 106.1 0.9 9.7e-31 105.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.16 AIF83893.1 - 4.4e-26 90.3 0.1 5.5e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L23 PF00276.15 AIF83894.1 - 1.2e-12 47.5 1.6 7.5e-12 45.0 1.1 1.9 1 1 0 1 1 1 1 Ribosomal protein L23 RRM_6 PF14259.1 AIF83894.1 - 0.027 14.4 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SynMuv_product PF06047.6 AIF83894.1 - 0.05 13.3 0.2 0.072 12.8 0.2 1.2 1 0 0 1 1 1 0 Ras-induced vulval development antagonist Peroxin-22 PF12827.2 AIF83894.1 - 0.098 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family RRM_5 PF13893.1 AIF83894.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.17 AIF83895.1 - 3.8e-37 127.5 0.9 4.4e-37 127.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.17 AIF83896.1 - 2.3e-56 191.1 3.1 2.6e-56 190.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Stap_Strp_toxin PF01123.15 AIF83896.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain Methyltrn_RNA_3 PF02598.12 AIF83897.1 - 5.2e-44 150.7 0.0 6.2e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SPOUT_MTase_2 PF14419.1 AIF83897.1 - 6.3e-05 22.2 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP AhpC-TSA PF00578.16 AIF83898.1 - 4.8e-09 35.9 0.0 3e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIF83898.1 - 2.9e-08 33.4 0.0 4.1e-06 26.4 0.0 2.3 1 1 0 2 2 2 2 Redoxin Thioredoxin_2 PF13098.1 AIF83898.1 - 0.00043 20.4 0.1 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain GSHPx PF00255.14 AIF83898.1 - 0.0057 16.0 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_8 PF13905.1 AIF83898.1 - 0.067 13.3 0.1 3.7 7.7 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like Proteasome PF00227.21 AIF83899.1 - 2e-57 193.5 0.4 2.6e-57 193.1 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AIF83899.1 - 8.8e-15 53.7 0.8 5.1e-14 51.2 0.1 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Synuclein PF01387.12 AIF83899.1 - 0.016 15.1 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 Synuclein DUF371 PF04027.8 AIF83901.1 - 6.6e-42 142.2 0.5 7.2e-42 142.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) HTH_20 PF12840.2 AIF83902.1 - 1.2e-12 47.4 0.5 5.7e-12 45.2 0.1 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF83902.1 - 5.1e-10 38.8 0.1 3.5e-09 36.1 0.1 2.1 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family PadR PF03551.9 AIF83902.1 - 4.8e-05 23.0 0.1 0.00013 21.6 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_12 PF08461.5 AIF83902.1 - 6.4e-05 22.5 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain TrmB PF01978.14 AIF83902.1 - 0.00023 20.7 0.1 0.00055 19.5 0.1 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AIF83902.1 - 0.00029 20.1 0.0 0.0007 18.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF2088 PF09861.4 AIF83902.1 - 0.0067 15.4 0.4 0.027 13.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2088) FUR PF01475.14 AIF83902.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family MarR_2 PF12802.2 AIF83902.1 - 0.012 15.2 0.0 0.064 12.9 0.0 2.1 1 1 0 1 1 1 0 MarR family HTH_11 PF08279.7 AIF83902.1 - 0.021 14.4 0.0 0.29 10.8 0.0 2.3 1 1 0 1 1 1 0 HTH domain Ribosomal_L12 PF00542.14 AIF83902.1 - 0.025 14.5 2.2 1 9.3 0.0 2.6 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain TFIIE_alpha PF02002.12 AIF83902.1 - 0.036 13.5 0.0 0.084 12.3 0.0 1.6 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_IclR PF09339.5 AIF83902.1 - 0.049 13.2 1.0 0.21 11.1 0.2 2.3 2 1 0 2 2 2 0 IclR helix-turn-helix domain DUF4423 PF14394.1 AIF83902.1 - 0.059 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF2250 PF10007.4 AIF83902.1 - 0.074 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) SAICAR_synt PF01259.13 AIF83903.1 - 9.2e-67 224.7 0.0 1.1e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase ATP-grasp PF02222.17 AIF83904.1 - 7.3e-59 197.9 0.1 1.2e-58 197.3 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AIF83904.1 - 1.6e-17 63.8 0.1 2.5e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIF83904.1 - 1.5e-09 37.1 0.3 7.1e-07 28.2 0.1 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 AIF83904.1 - 1.6e-07 30.9 0.1 3.4e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 AIF83904.1 - 4.1e-07 29.5 0.1 2.5e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 AIF83904.1 - 9.9e-05 21.5 0.0 0.00022 20.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 AIF83904.1 - 0.011 15.7 0.2 0.16 11.9 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 AIF83904.1 - 0.018 14.7 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GARS_A PF01071.14 AIF83904.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain XdhC_C PF13478.1 AIF83904.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ATP-grasp_5 PF13549.1 AIF83904.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain NAD_binding_2 PF03446.10 AIF83904.1 - 0.045 13.6 0.1 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_CoxI PF02625.11 AIF83904.1 - 0.05 13.2 0.1 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 XdhC and CoxI family ATP-grasp_2 PF08442.5 AIF83904.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DAO PF01266.19 AIF83904.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AIRC PF00731.15 AIF83905.1 - 1.3e-68 229.0 1.7 1.5e-68 228.8 1.2 1.1 1 0 0 1 1 1 1 AIR carboxylase CoA_binding_2 PF13380.1 AIF83905.1 - 0.012 15.8 0.1 4.3 7.5 0.0 2.2 1 1 1 2 2 2 0 CoA binding domain Nif11 PF07862.6 AIF83907.1 - 0.12 12.3 0.3 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function SpoIIAA-like PF11964.3 AIF83908.1 - 0.032 14.5 0.2 0.2 11.9 0.0 2.4 2 1 0 2 2 2 0 SpoIIAA-like CDC48_N PF02359.13 AIF83909.1 - 1.2e-19 70.0 0.0 2.9e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 AIF83909.1 - 9.8e-05 21.9 0.0 0.00028 20.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 adh_short PF00106.20 AIF83910.1 - 5.3e-32 111.0 0.1 1.1e-23 84.0 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 AIF83910.1 - 1.4e-21 77.3 0.4 2.4e-16 60.2 0.0 3.1 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF83910.1 - 5.6e-17 61.9 0.6 3.1e-11 43.2 0.0 3.5 4 1 0 4 4 4 2 KR domain Epimerase PF01370.16 AIF83910.1 - 7.1e-07 28.8 0.5 0.021 14.2 0.1 2.6 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 AIF83910.1 - 0.00041 20.0 1.6 0.00046 19.9 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 AIF83910.1 - 0.0015 17.7 0.8 0.0033 16.5 0.2 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 AIF83910.1 - 0.0082 15.5 0.1 2 7.8 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 AIF83910.1 - 0.015 15.3 2.3 0.65 9.9 0.2 3.2 2 1 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 AIF83910.1 - 0.02 15.3 2.5 0.032 14.6 0.2 2.6 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 AIF83910.1 - 0.03 13.4 0.3 0.12 11.4 0.1 2.2 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 AIF83910.1 - 0.053 13.7 0.7 0.29 11.3 0.1 2.5 3 1 0 3 3 3 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 AIF83910.1 - 0.056 13.2 2.4 0.059 13.1 0.2 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HMG_box_5 PF14887.1 AIF83910.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Shikimate_DH PF01488.15 AIF83910.1 - 0.15 12.1 0.2 0.15 12.1 0.1 2.4 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase TauE PF01925.14 AIF83911.1 - 7.4e-50 169.6 35.0 9.2e-50 169.3 24.3 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3482 PF11981.3 AIF83911.1 - 2.2 7.4 5.0 11 5.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) HTH_AsnC-type PF13404.1 AIF83912.1 - 2.9e-11 42.6 0.2 2.9e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 AIF83912.1 - 6e-10 38.6 0.0 9.9e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 AIF83912.1 - 1.9e-09 36.7 0.2 3.6e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AIF83912.1 - 8.8e-06 25.2 0.1 2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.7 AIF83912.1 - 0.00091 18.7 0.3 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HrcA_DNA-bdg PF03444.10 AIF83912.1 - 0.002 17.4 0.1 0.0049 16.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding NapD PF03927.8 AIF83912.1 - 0.003 17.3 0.1 0.0059 16.4 0.1 1.4 1 0 0 1 1 1 1 NapD protein Adeno_PX PF05829.7 AIF83912.1 - 0.0033 16.8 0.4 0.0077 15.7 0.3 1.7 1 0 0 1 1 1 1 Adenovirus late L2 mu core protein (Protein X) HTH_23 PF13384.1 AIF83912.1 - 0.0068 16.0 0.4 0.03 13.9 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 AIF83912.1 - 0.01 15.2 0.2 0.023 14.1 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.1 AIF83912.1 - 0.012 15.3 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.17 AIF83912.1 - 0.015 15.0 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 MarR family TrmB PF01978.14 AIF83912.1 - 0.015 14.9 0.2 0.12 12.1 0.0 2.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AIF83912.1 - 0.018 14.6 1.1 0.098 12.3 0.1 2.2 2 0 0 2 2 2 0 MarR family Replic_Relax PF13814.1 AIF83912.1 - 0.022 14.6 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation DUF2250 PF10007.4 AIF83912.1 - 0.023 14.5 0.0 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) FaeA PF04703.7 AIF83912.1 - 0.028 14.5 0.1 6.3 7.0 0.0 2.3 1 1 1 2 2 2 0 FaeA-like protein HTH_20 PF12840.2 AIF83912.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain GntR PF00392.16 AIF83912.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Mga PF08280.6 AIF83912.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4 PF04545.11 AIF83912.1 - 0.11 11.7 0.3 0.25 10.7 0.1 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 Homoserine_dh PF00742.14 AIF83913.1 - 4.8e-55 185.9 0.2 9.9e-55 184.9 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 AIF83913.1 - 7.7e-08 32.7 0.1 5.2e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 AIF83913.1 - 3.3e-05 23.5 0.1 8.5e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAM150 PF15129.1 AIF83913.1 - 0.024 14.5 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 FAM150 family GFO_IDH_MocA PF01408.17 AIF83913.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DZR PF12773.2 AIF83914.1 - 0.026 14.3 1.0 0.043 13.6 0.7 1.4 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 AIF83914.1 - 0.049 13.4 0.2 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 Zinc-ribbon BLIP PF07467.6 AIF83914.1 - 0.076 12.6 0.2 0.076 12.6 0.2 1.1 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) zf-B_box PF00643.19 AIF83914.1 - 0.11 12.4 0.3 5.7 6.9 0.0 2.0 2 0 0 2 2 2 0 B-box zinc finger zf-FPG_IleRS PF06827.9 AIF83914.1 - 0.15 11.7 1.3 8.2 6.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF1451 PF07295.6 AIF83914.1 - 0.17 11.6 1.1 0.19 11.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) RRN7 PF11781.3 AIF83914.1 - 2.8 7.5 5.5 18 4.9 3.8 2.0 1 1 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Phage_integrase PF00589.17 AIF83915.1 - 4.1e-09 36.3 0.1 1.1e-08 34.9 0.1 1.7 1 1 0 1 1 1 1 Phage integrase family zf-HIT PF04438.11 AIF83916.1 - 0.0011 18.5 20.5 0.035 13.7 1.5 3.8 3 0 0 3 3 3 2 HIT zinc finger DUF1272 PF06906.6 AIF83916.1 - 0.0028 17.4 11.9 0.12 12.2 1.3 3.2 2 1 0 3 3 3 2 Protein of unknown function (DUF1272) Ecl1 PF12855.2 AIF83916.1 - 0.034 13.4 10.9 0.54 9.5 0.3 3.2 3 0 0 3 3 3 0 Life-span regulatory factor DUF2688 PF10892.3 AIF83916.1 - 0.12 12.0 2.6 7.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) NinG PF05766.7 AIF83916.1 - 0.62 9.7 13.2 0.38 10.4 2.8 2.7 2 1 1 3 3 3 0 Bacteriophage Lambda NinG protein Fer4_9 PF13187.1 AIF83916.1 - 1.1 9.5 17.3 0.69 10.2 5.2 3.2 1 1 3 4 4 4 0 4Fe-4S dicluster domain zinc_ribbon_2 PF13240.1 AIF83916.1 - 1.5 8.3 14.1 1.2 8.7 0.0 4.2 5 0 0 5 5 5 0 zinc-ribbon domain DUF329 PF03884.9 AIF83916.1 - 1.6 8.3 14.6 1.6 8.3 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF329) RNA_POL_M_15KD PF02150.11 AIF83916.1 - 3.1 7.5 9.9 5.3 6.8 0.0 3.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DZR PF12773.2 AIF83916.1 - 3.3 7.6 17.8 1.3 8.8 0.3 3.4 2 1 0 2 2 2 0 Double zinc ribbon zf-MYND PF01753.13 AIF83916.1 - 4.6 7.2 21.5 3.6 7.5 1.8 3.4 2 1 0 2 2 2 0 MYND finger DUF501 PF04417.7 AIF83917.1 - 0.7 9.7 4.3 0.56 10.0 1.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Nop53 PF07767.6 AIF83917.1 - 1.4 7.7 13.8 1.6 7.6 9.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) APG6 PF04111.7 AIF83917.1 - 4.6 6.1 8.8 5.4 5.9 6.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 MSP PF01716.13 AIF83923.1 - 0.053 12.5 0.0 0.074 12.1 0.0 1.1 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide RHH_1 PF01402.16 AIF83924.1 - 0.0018 18.1 1.5 0.0075 16.1 0.1 2.5 3 0 0 3 3 3 1 Ribbon-helix-helix protein, copG family KH_5 PF13184.1 AIF83924.1 - 0.013 15.2 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 NusA-like KH domain A2M_N PF01835.14 AIF83926.1 - 0.00039 20.6 0.2 0.0013 18.9 0.0 1.9 2 0 0 2 2 2 1 MG2 domain TIG PF01833.19 AIF83926.1 - 0.015 15.3 3.9 0.038 13.9 2.7 1.9 1 0 0 1 1 1 0 IPT/TIG domain DUF3357 PF11837.3 AIF83926.1 - 0.041 13.7 0.7 0.1 12.4 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4251 PF14059.1 AIF83926.1 - 0.13 12.0 3.2 0.2 11.4 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4251) InvH PF04741.7 AIF83926.1 - 1.5 8.6 4.8 0.52 10.1 1.2 1.8 2 0 0 2 2 2 0 InvH outer membrane lipoprotein Jag_N PF14804.1 AIF83927.1 - 0.19 11.7 1.3 0.28 11.2 0.9 1.3 1 0 0 1 1 1 0 Jag N-terminus Glycos_transf_1 PF00534.15 AIF83928.1 - 1.9e-20 72.9 0.0 2.8e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AIF83928.1 - 2.8e-05 24.2 0.0 5.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AIF83928.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 CBS PF00571.23 AIF83929.1 - 2.4e-13 49.6 0.0 3.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 CBS domain GAGA PF09237.6 AIF83929.1 - 0.005 16.3 0.6 0.0087 15.6 0.0 1.6 2 0 0 2 2 2 1 GAGA factor zf-Di19 PF05605.7 AIF83929.1 - 0.014 15.4 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF72 PF01904.13 AIF83932.1 - 5.4e-13 49.2 0.0 5.7e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 DUF72 PF01904.13 AIF83933.1 - 1e-16 61.4 0.0 1.1e-16 61.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 Crystall PF00030.14 AIF83934.1 - 0.067 13.0 0.2 0.084 12.7 0.2 1.3 1 1 0 1 1 1 0 Beta/Gamma crystallin zf-TFIIB PF13453.1 AIF83935.1 - 0.0028 16.8 2.2 0.45 9.7 0.3 2.2 2 0 0 2 2 2 2 Transcription factor zinc-finger DUF2296 PF10058.4 AIF83935.1 - 0.028 14.1 0.8 0.05 13.3 0.6 1.5 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) NOB1_Zn_bind PF08772.6 AIF83935.1 - 0.028 14.2 0.2 0.033 14.0 0.2 1.2 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF1451 PF07295.6 AIF83935.1 - 0.037 13.7 0.3 0.053 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Baculo_IE-1 PF05290.6 AIF83935.1 - 0.053 13.2 0.2 0.064 12.9 0.2 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ribbon_3 PF13248.1 AIF83935.1 - 0.058 12.6 4.5 0.25 10.6 3.2 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.4 AIF83935.1 - 0.083 12.7 0.3 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DZR PF12773.2 AIF83935.1 - 0.09 12.6 1.7 0.2 11.5 1.2 1.6 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 AIF83935.1 - 0.1 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S27 Cys_rich_CPCC PF14206.1 AIF83935.1 - 0.11 12.0 3.0 3.1 7.4 0.1 2.1 1 1 1 2 2 2 0 Cysteine-rich CPCC DUF164 PF02591.10 AIF83935.1 - 0.12 12.1 1.7 0.4 10.5 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 AIF83935.1 - 0.12 12.2 1.5 0.38 10.7 1.2 1.7 1 1 1 2 2 2 0 Zinc ribbon domain zf-IS66 PF13005.2 AIF83935.1 - 0.19 11.7 0.3 0.19 11.7 0.2 1.6 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Nudix_N_2 PF14803.1 AIF83935.1 - 0.85 9.3 3.6 3.6 7.3 0.4 2.3 2 0 0 2 2 2 0 Nudix N-terminal DNA_ligase_ZBD PF03119.11 AIF83935.1 - 3.3 7.5 8.0 0.26 11.0 1.9 2.0 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF3482 PF11981.3 AIF83936.1 - 0.09 11.9 1.1 0.099 11.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) NTF-like PF14540.1 AIF83937.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase-like Bap31 PF05529.7 AIF83938.1 - 0.0025 17.2 2.0 0.0028 17.1 1.4 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 AIF83938.1 - 0.0058 17.0 2.1 0.0064 16.9 1.5 1.0 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 AIF83938.1 - 0.0064 16.2 3.8 0.0071 16.1 2.6 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.1 AIF83938.1 - 0.0075 15.7 2.6 0.0075 15.7 1.8 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.10 AIF83938.1 - 0.01 15.2 2.5 0.011 15.2 1.7 1.1 1 0 0 1 1 1 0 Septum formation initiator DUF1811 PF08838.5 AIF83938.1 - 0.013 15.4 1.8 0.017 15.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) GAS PF13851.1 AIF83938.1 - 0.018 14.2 3.3 0.019 14.1 2.3 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 AIF83938.1 - 0.031 14.0 1.0 0.031 14.0 0.7 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 AIF83938.1 - 0.032 14.2 2.6 0.033 14.2 1.8 1.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 AIF83938.1 - 0.035 14.0 1.9 0.038 13.8 1.3 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CCDC-167 PF15188.1 AIF83938.1 - 0.037 13.9 2.1 0.036 13.9 1.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spectrin PF00435.16 AIF83938.1 - 0.037 14.3 0.4 0.04 14.2 0.3 1.1 1 0 0 1 1 1 0 Spectrin repeat Macoilin PF09726.4 AIF83938.1 - 0.038 12.2 2.6 0.036 12.3 1.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Med9 PF07544.8 AIF83938.1 - 0.041 13.6 3.5 0.048 13.3 2.4 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TPD52 PF04201.10 AIF83938.1 - 0.044 13.5 3.2 0.04 13.6 2.2 1.1 1 0 0 1 1 1 0 Tumour protein D52 family Mod_r PF07200.8 AIF83938.1 - 0.044 13.6 1.5 0.041 13.7 1.1 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.1 AIF83938.1 - 0.062 13.2 5.5 0.071 13.0 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 AIF83938.1 - 0.078 12.7 2.0 0.076 12.8 1.4 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 AIF83938.1 - 0.079 13.0 1.0 0.082 13.0 0.7 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 AIF83938.1 - 0.082 12.5 1.7 0.079 12.6 1.1 1.0 1 0 0 1 1 1 0 Mnd1 family Prefoldin_2 PF01920.15 AIF83938.1 - 0.1 12.3 3.0 0.11 12.2 2.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit Phage_GP20 PF06810.6 AIF83938.1 - 0.12 11.8 1.7 0.12 11.8 1.2 1.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 DMPK_coil PF08826.5 AIF83938.1 - 0.22 11.4 4.0 0.8 9.6 1.9 1.9 1 1 1 2 2 2 0 DMPK coiled coil domain like Lzipper-MIP1 PF14389.1 AIF83938.1 - 0.35 11.0 5.0 0.48 10.5 3.5 1.3 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.13 AIF83938.1 - 0.42 10.5 3.0 0.53 10.2 2.1 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family Cep57_MT_bd PF06657.8 AIF83938.1 - 0.48 10.4 4.4 0.55 10.2 3.0 1.1 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Atg14 PF10186.4 AIF83938.1 - 0.51 9.2 5.0 0.5 9.2 3.4 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1192 PF06698.6 AIF83938.1 - 1.2 9.0 4.8 1.5 8.6 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Pox_A_type_inc PF04508.7 AIF83938.1 - 1.7 8.6 5.8 1.8 8.5 2.5 2.1 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat zinc_ribbon_5 PF13719.1 AIF83942.1 - 0.021 14.4 1.3 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.4 AIF83942.1 - 0.021 14.6 0.2 0.071 12.9 0.0 1.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF3133 PF11331.3 AIF83942.1 - 0.031 13.8 0.2 1.6 8.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) HypA PF01155.14 AIF83942.1 - 0.032 13.9 0.2 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family FdhE PF04216.7 AIF83942.1 - 0.057 13.1 0.7 0.057 13.1 0.5 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Tmemb_55A PF09788.4 AIF83942.1 - 0.062 12.4 0.2 0.068 12.2 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A zf-RING_2 PF13639.1 AIF83942.1 - 0.074 12.8 1.3 0.11 12.3 0.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-CHY PF05495.7 AIF83942.1 - 0.094 12.8 0.3 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 CHY zinc finger zf-C3HC4_2 PF13923.1 AIF83942.1 - 0.12 12.3 1.3 0.16 12.0 0.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AIF83942.1 - 0.14 11.8 1.0 0.22 11.2 0.7 1.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HMA PF00403.21 AIF83942.1 - 0.14 12.2 0.6 11 6.2 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain zinc_ribbon_4 PF13717.1 AIF83942.1 - 0.19 11.4 2.8 6.2 6.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Opy2 PF09463.5 AIF83942.1 - 0.2 11.8 2.6 8.9 6.4 0.2 2.1 2 0 0 2 2 2 0 Opy2 protein DNA_RNApol_7kD PF03604.8 AIF83942.1 - 0.32 10.4 1.9 0.74 9.3 0.1 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF2082 PF09855.4 AIF83942.1 - 0.35 10.7 2.6 0.61 9.9 0.1 2.1 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 AIF83942.1 - 0.42 10.3 2.7 0.44 10.2 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Cys_rich_KTR PF14205.1 AIF83942.1 - 0.81 9.1 3.3 4 6.9 0.3 2.1 1 1 1 2 2 2 0 Cysteine-rich KTR Mu-like_Com PF10122.4 AIF83942.1 - 0.98 8.5 5.4 3 6.9 3.8 1.8 1 1 0 1 1 1 0 Mu-like prophage protein Com HupE_UreJ PF04955.7 AIF83943.1 - 0.0078 15.5 0.5 0.0078 15.5 0.4 1.1 1 0 0 1 1 1 1 HupE / UreJ protein DUF1469 PF07332.6 AIF83945.1 - 0.00047 19.8 3.1 0.00053 19.7 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) COG5 PF10392.4 AIF83946.1 - 0.031 14.2 0.4 0.088 12.7 0.3 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Spc7 PF08317.6 AIF83946.1 - 0.4 9.2 4.2 0.96 8.0 2.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein PLDc_2 PF13091.1 AIF83954.1 - 2.4e-18 66.0 0.1 3.3e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.17 AIF83954.1 - 2.4e-06 27.1 0.0 1.2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase D Active site motif AIM24 PF01987.12 AIF83955.1 - 1.6e-53 181.3 2.5 1.8e-53 181.1 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF3217 PF11506.3 AIF83955.1 - 0.094 12.4 0.1 2 8.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3217) PUA PF01472.15 AIF83956.1 - 8.5e-17 60.6 0.3 8.5e-17 60.6 0.2 1.5 2 0 0 2 2 2 1 PUA domain HTH_24 PF13412.1 AIF83957.1 - 2e-08 33.4 0.4 4.7e-08 32.2 0.3 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF83957.1 - 4.3e-05 22.9 0.6 0.0001 21.7 0.4 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_28 PF13518.1 AIF83957.1 - 0.0032 17.4 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 AIF83957.1 - 0.011 15.2 0.1 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.2 AIF83957.1 - 0.012 15.4 0.0 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.2 AIF83957.1 - 0.036 13.7 0.1 0.077 12.6 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_8 PF02954.14 AIF83957.1 - 0.036 13.6 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_11 PF08279.7 AIF83957.1 - 0.042 13.4 0.3 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 HTH domain HTH_23 PF13384.1 AIF83957.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain Proteasome PF00227.21 AIF83958.1 - 3.3e-49 166.7 0.0 3.9e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HATPase_c_3 PF13589.1 AIF83959.1 - 9.2e-12 44.7 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AIF83959.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Copper-bind PF00127.15 AIF83960.1 - 3e-08 33.8 0.0 4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF83960.1 - 2.3e-06 27.4 0.1 4.8e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Cupredoxin-like domain Pilin PF00114.14 AIF83960.1 - 0.086 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Pilin (bacterial filament) eRF1_2 PF03464.10 AIF83961.1 - 1.1e-34 119.6 0.0 2.6e-34 118.3 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_1 PF03463.10 AIF83961.1 - 8e-19 67.5 0.0 1.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 AIF83961.1 - 2.8e-18 66.2 0.3 6.4e-18 65.0 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 HypA PF01155.14 AIF83961.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-FPG_IleRS PF06827.9 AIF83961.1 - 0.1 12.2 0.4 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Prim_Zn_Ribbon PF08273.7 AIF83961.1 - 0.16 12.1 0.6 0.49 10.5 0.4 1.8 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Lar_restr_allev PF14354.1 AIF83961.1 - 0.22 11.8 2.1 0.44 10.8 0.2 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 AIF83961.1 - 1.2 9.1 4.9 2.4 8.1 1.9 2.5 2 1 0 2 2 2 0 Zinc ribbon domain CBS PF00571.23 AIF83962.1 - 9.1e-16 57.3 3.6 7.9e-12 44.7 0.1 2.8 2 1 0 2 2 2 2 CBS domain HTH_3 PF01381.17 AIF83962.1 - 8.2e-13 47.9 0.2 1.7e-12 47.0 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.2 AIF83962.1 - 1.3e-12 47.6 0.1 3.4e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 AIF83962.1 - 1.8e-12 47.2 0.0 2.7e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 AIF83962.1 - 0.00044 19.8 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain CoA_binding_2 PF13380.1 AIF83962.1 - 0.005 16.9 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain HTH_37 PF13744.1 AIF83962.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.1 AIF83962.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF1072 PF06380.6 AIF83963.1 - 8.5 6.1 7.2 1.9 8.2 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Gp_dh_N PF00044.19 AIF83964.1 - 3.5e-09 36.7 1.5 1.2e-08 35.0 0.6 2.3 3 1 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AIF83964.1 - 1.1e-05 25.3 0.3 2.6e-05 24.1 0.2 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 AIF83964.1 - 0.0011 19.3 0.1 0.0027 18.1 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 AIF83964.1 - 0.0021 17.5 0.0 0.027 13.9 0.0 2.4 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain F420_oxidored PF03807.12 AIF83964.1 - 0.017 15.5 0.5 0.17 12.3 0.4 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 AIF83964.1 - 0.038 13.9 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain GATase PF00117.23 AIF83965.1 - 7.7e-57 191.8 0.0 8.6e-57 191.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIF83965.1 - 3.3e-11 43.0 0.0 5.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Glycos_transf_3 PF00591.16 AIF83966.1 - 8.6e-80 267.7 1.2 8.6e-80 267.7 0.9 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 AIF83966.1 - 2.2e-19 68.7 2.6 4.2e-19 67.8 1.8 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Rad51 PF08423.6 AIF83967.1 - 1.6e-89 299.1 0.0 2.1e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 AIF83967.1 - 9.8e-12 44.4 0.3 3.9e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 AIF83967.1 - 8.2e-11 41.6 0.0 1.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 AIF83967.1 - 9.6e-11 41.7 0.8 2.1e-10 40.6 0.2 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 AIF83967.1 - 2e-09 36.9 0.1 3.1e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DUF4332 PF14229.1 AIF83967.1 - 0.00074 19.4 0.0 0.0028 17.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) DNA_pol_lambd_f PF10391.4 AIF83967.1 - 0.0015 18.0 0.0 0.0047 16.4 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.3 AIF83967.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Pathogenicity locus TfoX_C PF04994.8 AIF83967.1 - 0.0065 16.3 0.0 0.018 14.9 0.0 1.8 1 1 0 1 1 1 1 TfoX C-terminal domain HHH PF00633.18 AIF83967.1 - 0.0072 15.9 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA PF00004.24 AIF83967.1 - 0.036 14.2 0.1 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IMS_HHH PF11798.3 AIF83967.1 - 0.071 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif TrwB_AAD_bind PF10412.4 AIF83967.1 - 0.087 11.4 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Auto_anti-p27 PF06677.7 AIF83968.1 - 0.11 12.2 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) UPF0184 PF03670.8 AIF83969.1 - 0.0021 18.1 4.3 0.41 10.8 0.1 3.4 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0184) BcsB PF03170.8 AIF83969.1 - 0.0039 15.2 0.7 0.0077 14.3 0.2 1.5 1 1 0 1 1 1 1 Bacterial cellulose synthase subunit UPF0228 PF05727.6 AIF83969.1 - 0.022 14.4 0.4 0.022 14.4 0.3 2.7 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0228) His_kinase PF06580.8 AIF83969.1 - 0.062 13.2 0.3 0.21 11.5 0.2 1.9 1 0 0 1 1 1 0 Histidine kinase DUF2408 PF10303.4 AIF83969.1 - 0.091 12.8 8.6 0.064 13.3 3.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) TarH PF02203.10 AIF83969.1 - 0.15 11.9 12.5 0.89 9.3 3.6 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue Reo_sigmaC PF04582.7 AIF83969.1 - 0.17 11.0 6.6 0.13 11.3 1.3 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein FUSC PF04632.7 AIF83969.1 - 0.2 10.0 3.4 0.26 9.7 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.8 AIF83969.1 - 0.27 10.2 7.3 0.04 12.9 1.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein WASH_WAHD PF11945.3 AIF83969.1 - 0.58 9.4 11.1 1.1 8.5 7.7 1.3 1 1 0 1 1 1 0 WAHD domain of WASH complex Uso1_p115_C PF04871.8 AIF83969.1 - 0.61 10.0 15.8 0.044 13.7 3.7 3.3 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.7 AIF83969.1 - 0.91 9.8 8.2 9.4 6.5 0.5 3.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 AIF83969.1 - 0.98 8.2 16.9 0.02 13.8 3.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 AIF83969.1 - 2.9 8.2 12.6 21 5.5 2.8 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 AIF83969.1 - 3.7 7.3 13.7 0.84 9.4 1.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6 PF04111.7 AIF83969.1 - 4.6 6.1 14.5 0.32 10.0 3.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Calci_bind_CcbP PF11535.3 AIF83970.1 - 0.092 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Calcium binding Trp_syntA PF00290.15 AIF83971.1 - 5.6e-92 306.9 0.0 6.4e-92 306.7 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PcrB PF01884.12 AIF83971.1 - 1.2e-06 27.9 0.2 6.2e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 PcrB family His_biosynth PF00977.16 AIF83971.1 - 2.1e-06 27.2 0.0 3.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 AIF83971.1 - 0.0007 18.7 0.0 0.0019 17.3 0.0 1.6 2 0 0 2 2 2 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 AIF83971.1 - 0.0048 16.0 0.1 0.0091 15.0 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 AIF83971.1 - 0.014 14.4 0.2 0.042 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 AIF83971.1 - 0.064 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase OMP_b-brl PF13505.1 AIF83971.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Pterin_bind PF00809.17 AIF83971.1 - 0.22 10.8 1.3 6.2 6.1 0.1 3.1 3 1 1 4 4 4 0 Pterin binding enzyme PALP PF00291.20 AIF83972.1 - 9.9e-40 136.6 0.4 1.2e-39 136.3 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Phage_min_cap2 PF06152.6 AIF83972.1 - 0.088 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 IGPS PF00218.16 AIF83973.1 - 2.1e-65 220.3 0.5 2.5e-65 220.0 0.3 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 AIF83973.1 - 2.5e-05 23.3 1.2 6.9e-05 21.8 0.8 1.7 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 AIF83973.1 - 0.0015 17.8 0.1 0.024 13.8 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.14 AIF83973.1 - 0.0049 16.4 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 AIF83973.1 - 0.014 14.6 0.7 0.037 13.2 0.1 1.9 2 0 0 2 2 2 0 PcrB family ThiG PF05690.9 AIF83973.1 - 0.02 13.9 2.5 0.13 11.3 0.0 2.4 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Hydrolase_like PF13242.1 AIF83973.1 - 0.069 12.8 0.0 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 HAD-hyrolase-like AAA_22 PF13401.1 AIF83974.1 - 4.2e-10 39.8 0.2 1.6e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AIF83974.1 - 3.9e-07 30.2 0.1 1.8e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AIF83974.1 - 1.1e-05 25.5 0.0 3.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AIF83974.1 - 1.7e-05 24.6 0.3 6.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 AIF83974.1 - 0.00016 20.6 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 AIF83974.1 - 0.012 16.4 0.2 0.67 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 AIF83974.1 - 0.018 14.4 0.8 0.039 13.3 0.6 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 AIF83974.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 AIF83974.1 - 0.057 13.1 0.6 3 7.5 0.3 2.6 2 0 0 2 2 2 0 NTPase MarR_2 PF12802.2 AIF83974.1 - 0.07 12.8 0.4 0.35 10.5 0.1 2.3 2 0 0 2 2 2 0 MarR family AAA_14 PF13173.1 AIF83974.1 - 0.12 12.2 3.0 0.14 12.0 0.7 2.0 2 1 0 2 2 2 0 AAA domain TrmB PF01978.14 AIF83975.1 - 0.014 15.0 0.1 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.6 AIF83975.1 - 0.036 13.8 0.1 0.044 13.5 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_IclR PF09339.5 AIF83975.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain CTP_synth_N PF06418.9 AIF83979.1 - 2.4e-123 410.6 0.1 3e-123 410.3 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AIF83979.1 - 9.7e-44 149.1 0.0 1.7e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIF83979.1 - 8.7e-10 38.4 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 AIF83979.1 - 3.4e-07 29.8 0.1 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NAD_kinase PF01513.16 AIF83980.1 - 4.4e-34 117.5 0.3 5.6e-34 117.2 0.2 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MarR PF01047.17 AIF83980.1 - 0.0011 18.6 0.2 0.002 17.7 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 AIF83980.1 - 0.0018 17.9 0.1 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AIF83980.1 - 0.0034 17.6 0.2 0.0077 16.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 AIF83980.1 - 0.013 15.2 0.1 0.036 13.7 0.1 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AIF83980.1 - 0.037 13.4 0.1 0.081 12.3 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FeoC PF09012.5 AIF83980.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator TFIIE_alpha PF02002.12 AIF83980.1 - 0.084 12.3 0.1 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit RNA_pol_Rpc34 PF05158.7 AIF83980.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit PfkB PF00294.19 AIF83981.1 - 2.8e-09 36.5 0.0 6.4e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AIF83981.1 - 0.013 14.6 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Ribosomal_S26e PF01283.14 AIF83982.1 - 4.1e-30 104.3 1.3 4.9e-30 104.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf-dskA_traR PF01258.12 AIF83982.1 - 0.0097 15.6 0.1 0.87 9.3 0.0 2.3 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger DUF2112 PF09885.4 AIF83982.1 - 0.082 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) DZR PF12773.2 AIF83982.1 - 0.1 12.4 0.2 0.29 10.9 0.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.7 AIF83982.1 - 0.12 12.1 2.1 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Lar_restr_allev PF14354.1 AIF83982.1 - 0.15 12.3 1.0 1.6 9.0 0.0 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar RRN7 PF11781.3 AIF83982.1 - 0.26 10.7 2.7 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 CDP-OH_P_transf PF01066.16 AIF83983.1 - 3.1e-16 59.5 2.6 3.1e-16 59.5 1.8 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UPF0220 PF05255.6 AIF83983.1 - 0.13 11.5 1.5 4.1 6.6 0.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0220) HTH_27 PF13463.1 AIF83984.1 - 0.0047 17.2 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Response_reg PF00072.19 AIF83985.1 - 2e-12 47.1 0.1 1.3e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AIF83986.1 - 1e-22 79.9 0.0 1.6e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF83986.1 - 5.2e-14 51.9 0.1 1.4e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain YtpI PF14007.1 AIF83986.1 - 0.039 13.8 0.3 0.039 13.8 0.2 3.3 3 1 1 4 4 4 0 YtpI-like protein HATPase_c_3 PF13589.1 AIF83986.1 - 0.053 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MerC PF03203.9 AIF83986.1 - 0.11 12.8 5.0 0.57 10.5 3.4 2.1 1 1 0 1 1 1 0 MerC mercury resistance protein DUF126 PF01989.11 AIF83987.1 - 0.083 12.5 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF126 adh_short_C2 PF13561.1 AIF83988.1 - 4.6e-31 108.4 0.1 5.7e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AIF83988.1 - 1.3e-27 96.7 0.1 1.5e-27 96.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIF83988.1 - 9.6e-11 41.6 0.1 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AIF83988.1 - 4.2e-05 23.0 0.2 0.00043 19.7 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 AIF83988.1 - 0.0063 15.6 0.0 0.05 12.7 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 AIF83988.1 - 0.021 13.8 0.1 0.041 12.9 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 AIF83988.1 - 0.07 12.0 1.0 0.56 9.0 0.5 2.4 1 1 1 2 2 2 0 RmlD substrate binding domain DUF1974 PF09317.6 AIF83988.1 - 0.12 11.7 0.4 0.29 10.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) DUF2946 PF11162.3 AIF83989.1 - 0.17 12.1 4.0 0.3 11.3 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) MarR PF01047.17 AIF83990.1 - 7.8e-12 44.7 0.0 1.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 AIF83990.1 - 5.8e-11 41.8 0.1 8.5e-11 41.3 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AIF83990.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.5 AIF83990.1 - 0.00066 19.2 0.1 0.0012 18.3 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 AIF83990.1 - 0.0008 18.7 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AIF83990.1 - 0.02 14.5 0.0 0.072 12.7 0.0 1.9 2 0 0 2 2 2 0 HTH domain DUF1380 PF07128.7 AIF83990.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) HTH_34 PF13601.1 AIF83990.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 AIF83990.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 AIF83990.1 - 0.032 14.3 0.1 0.062 13.4 0.0 1.5 2 0 0 2 2 2 0 Winged helix-turn helix FGase PF05013.7 AIF83990.1 - 0.1 12.4 0.5 1.3 8.8 0.0 2.1 1 1 1 2 2 2 0 N-formylglutamate amidohydrolase HTH_36 PF13730.1 AIF83990.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GSDH PF07995.6 AIF83991.1 - 5.6e-50 170.3 0.3 6.6e-50 170.0 0.2 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Aldolase_II PF00596.16 AIF83992.1 - 3.8e-42 143.9 1.0 4.3e-42 143.8 0.7 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ATP-synt_F PF01990.12 AIF83993.1 - 1.5e-17 63.7 0.0 1.6e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DHquinase_I PF01487.10 AIF83993.1 - 0.057 13.0 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Type I 3-dehydroquinase UBA PF00627.26 AIF83994.1 - 0.015 15.1 0.1 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 UBA/TS-N domain BCL_N PF04714.8 AIF83995.1 - 0.071 12.6 0.1 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 BCL7, N-terminal conserver region BT1 PF03092.11 AIF83995.1 - 0.089 11.4 0.1 0.089 11.4 0.0 1.0 1 0 0 1 1 1 0 BT1 family SIT PF15330.1 AIF83995.1 - 0.13 12.4 0.1 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Phage_pRha PF09669.5 AIF83995.1 - 0.16 12.3 0.3 0.16 12.3 0.2 1.0 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) DUF4044 PF13253.1 AIF83995.1 - 1.7 7.8 4.0 2.3 7.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) SnoaL PF07366.7 AIF83996.1 - 1.2e-35 121.8 0.0 1.4e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AIF83996.1 - 2.3e-20 72.9 0.0 2.8e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AIF83996.1 - 0.045 13.9 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SLH PF00395.15 AIF83997.1 - 0.037 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 S-layer homology domain DCAF15_WD40 PF14939.1 AIF83998.1 - 0.14 11.4 0.2 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat PrgI PF12666.2 AIF83999.1 - 0.043 13.9 0.2 0.046 13.8 0.1 1.1 1 0 0 1 1 1 0 PrgI family protein ATP_synt_I PF03899.10 AIF83999.1 - 0.61 10.2 5.2 1.3 9.1 3.6 1.6 1 1 0 1 1 1 0 ATP synthase I chain DnaJ PF00226.26 AIF84000.1 - 2.1e-27 94.6 3.8 3.7e-27 93.8 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain DUF1764 PF08576.5 AIF84000.1 - 0.054 14.2 0.7 0.079 13.7 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) ATP_Ca_trans_C PF12424.3 AIF84000.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal Abi PF02517.11 AIF84001.1 - 0.049 13.7 15.3 1.6 8.9 10.6 2.8 1 1 0 1 1 1 0 CAAX protease self-immunity DUF165 PF02592.10 AIF84001.1 - 0.65 10.1 6.4 0.26 11.4 2.2 1.9 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 DUF4234 PF14018.1 AIF84001.1 - 1.5 8.6 8.9 0.77 9.5 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Polyketide_cyc2 PF10604.4 AIF84002.1 - 3.6e-14 53.1 0.1 4e-14 52.9 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 AIF84002.1 - 7.2e-08 32.5 0.2 8.8e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.15 AIF84002.1 - 3.3e-05 23.8 0.2 4e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FixH PF05751.6 AIF84002.1 - 0.024 14.4 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 FixH APG6 PF04111.7 AIF84005.1 - 1.4e-06 27.6 11.6 0.0013 17.8 1.8 2.0 2 0 0 2 2 2 2 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 AIF84005.1 - 1.4e-05 24.8 20.9 0.00016 21.3 1.9 3.1 2 1 0 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 AIF84005.1 - 1.7e-05 25.0 11.4 0.024 14.9 2.2 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF972) ADIP PF11559.3 AIF84005.1 - 2.9e-05 24.0 9.6 0.0037 17.1 0.3 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 AIF84005.1 - 4.1e-05 23.7 16.3 0.016 15.4 3.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 AIF84005.1 - 8.5e-05 22.2 15.4 0.0048 16.6 2.6 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding HALZ PF02183.13 AIF84005.1 - 0.00028 20.5 20.2 0.17 11.6 0.7 5.0 3 2 2 5 5 5 2 Homeobox associated leucine zipper DUF848 PF05852.6 AIF84005.1 - 0.00061 19.6 7.8 0.021 14.6 0.7 2.1 2 0 0 2 2 2 2 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.10 AIF84005.1 - 0.00061 19.2 19.1 0.057 12.9 3.6 3.4 2 1 1 3 3 3 1 Septum formation initiator bZIP_1 PF00170.16 AIF84005.1 - 0.0025 17.7 18.9 0.32 10.9 0.5 4.3 2 2 2 4 4 4 3 bZIP transcription factor GAS PF13851.1 AIF84005.1 - 0.0031 16.7 15.0 0.12 11.5 3.6 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.1 AIF84005.1 - 0.0037 16.9 9.7 6.7 6.4 0.1 4.2 3 1 0 3 3 3 0 Sperm tail C-terminal domain Kinesin-relat_1 PF12711.2 AIF84005.1 - 0.004 17.5 10.3 0.059 13.7 1.6 3.5 2 2 2 4 4 4 1 Kinesin motor Lebercilin PF15619.1 AIF84005.1 - 0.0041 16.5 5.5 0.4 10.0 0.1 2.4 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.14 AIF84005.1 - 0.0054 14.6 2.6 0.007 14.2 1.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ATG16 PF08614.6 AIF84005.1 - 0.0056 16.5 18.3 0.03 14.1 5.4 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.1 AIF84005.1 - 0.0081 16.0 16.3 0.058 13.3 1.8 3.2 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 DUF4201 PF13870.1 AIF84005.1 - 0.0088 15.4 9.4 0.34 10.3 1.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4201) Rab5-bind PF09311.6 AIF84005.1 - 0.013 15.4 13.8 0.14 12.0 1.9 2.3 2 0 0 2 2 2 0 Rabaptin-like protein MAD PF05557.8 AIF84005.1 - 0.016 13.2 10.6 0.072 11.1 1.4 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein DivIVA PF05103.8 AIF84005.1 - 0.018 15.1 17.1 0.17 11.9 3.2 2.4 1 1 1 2 2 2 0 DivIVA protein Laminin_I PF06008.9 AIF84005.1 - 0.022 14.0 2.9 0.022 14.0 2.0 2.2 2 0 0 2 2 2 0 Laminin Domain I CENP-F_leu_zip PF10473.4 AIF84005.1 - 0.027 14.3 12.0 0.19 11.5 0.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.7 AIF84005.1 - 0.031 13.7 9.3 0.16 11.3 0.8 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like CtIP_N PF10482.4 AIF84005.1 - 0.04 13.7 5.9 0.22 11.3 0.7 2.5 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TBPIP PF07106.8 AIF84005.1 - 0.042 13.3 9.3 0.15 11.5 1.5 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 AIF84005.1 - 0.047 13.1 9.5 0.038 13.4 0.9 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 CCDC155 PF14662.1 AIF84005.1 - 0.065 12.8 16.3 0.27 10.7 3.3 2.5 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 IncA PF04156.9 AIF84005.1 - 0.066 12.7 17.1 0.85 9.1 11.9 2.0 1 1 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 AIF84005.1 - 0.078 12.8 21.3 0.35 10.7 0.5 4.5 2 2 2 4 4 4 0 Basic region leucine zipper Spc7 PF08317.6 AIF84005.1 - 0.095 11.3 8.0 0.27 9.8 0.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Takusan PF04822.8 AIF84005.1 - 0.12 12.1 2.4 1 9.1 0.2 2.4 2 1 0 2 2 2 0 Takusan Hormone_1 PF00103.15 AIF84005.1 - 0.12 11.7 3.6 0.1 11.9 0.3 2.0 2 0 0 2 2 2 0 Somatotropin hormone family TSC22 PF01166.13 AIF84005.1 - 0.2 11.6 7.4 21 5.1 0.0 3.8 2 2 1 3 3 3 0 TSC-22/dip/bun family DUF4407 PF14362.1 AIF84005.1 - 0.23 10.4 14.0 0.42 9.5 9.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) EzrA PF06160.7 AIF84005.1 - 0.25 9.5 10.2 0.41 8.7 6.6 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.7 AIF84005.1 - 0.29 10.8 21.7 0.44 10.2 6.8 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 AIF84005.1 - 0.36 10.1 19.1 0.26 10.6 3.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4591 PF15261.1 AIF84005.1 - 0.37 11.0 7.5 0.56 10.4 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) DUF3450 PF11932.3 AIF84005.1 - 0.46 9.7 20.5 0.6 9.3 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlgN PF05130.7 AIF84005.1 - 0.49 10.6 18.1 2 8.6 3.7 2.2 1 1 1 2 2 2 0 FlgN protein Ax_dynein_light PF10211.4 AIF84005.1 - 0.49 10.1 9.8 2.2 8.0 0.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Shugoshin_N PF07558.6 AIF84005.1 - 0.52 10.0 3.9 6.1 6.6 0.1 3.0 2 2 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Myosin_tail_1 PF01576.14 AIF84005.1 - 0.55 7.8 15.9 0.49 8.0 2.5 1.9 1 1 0 2 2 2 0 Myosin tail THOC7 PF05615.8 AIF84005.1 - 0.56 10.4 10.5 3.9 7.7 3.8 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 HAP1_N PF04849.8 AIF84005.1 - 0.64 8.9 11.8 6.4 5.6 7.8 2.5 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TLE_N PF03920.10 AIF84005.1 - 0.65 9.8 3.8 0.47 10.2 0.3 2.4 2 2 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain CENP-H PF05837.7 AIF84005.1 - 0.65 10.1 11.2 0.64 10.2 1.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Prominin PF05478.6 AIF84005.1 - 0.74 7.2 6.2 0.97 6.8 4.3 1.1 1 0 0 1 1 1 0 Prominin DUF4515 PF14988.1 AIF84005.1 - 0.74 9.4 11.9 1.6 8.3 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) Filament PF00038.16 AIF84005.1 - 0.87 8.9 13.8 9.6 5.5 5.9 2.4 1 1 1 2 2 2 0 Intermediate filament protein KfrA_N PF11740.3 AIF84005.1 - 1.2 9.6 31.4 0.97 9.8 6.5 3.1 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term DUF1640 PF07798.6 AIF84005.1 - 1.2 9.1 8.9 32 4.5 6.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.17 AIF84005.1 - 1.3 9.0 15.1 5.1 7.1 2.9 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.8 AIF84005.1 - 1.4 8.8 14.4 2.1 8.2 2.2 2.3 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.4 AIF84005.1 - 1.6 8.9 9.0 1.2 9.2 1.0 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hemerythrin PF01814.18 AIF84005.1 - 1.6 8.8 5.2 5 7.3 0.1 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF342 PF03961.8 AIF84005.1 - 1.7 6.9 6.7 3.9 5.7 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF724 PF05266.9 AIF84005.1 - 1.7 8.2 11.4 2.8 7.5 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) COG2 PF06148.6 AIF84005.1 - 1.8 8.4 6.2 2.5 7.9 0.4 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Nnf1 PF03980.9 AIF84005.1 - 2 8.4 13.6 3.7 7.5 0.8 3.6 1 1 2 4 4 4 0 Nnf1 Striatin PF08232.7 AIF84005.1 - 2.1 8.6 10.1 12 6.2 3.3 2.2 1 1 1 2 2 2 0 Striatin family CENP-Q PF13094.1 AIF84005.1 - 2.1 8.3 19.5 0.35 10.8 1.6 3.0 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DegS PF05384.6 AIF84005.1 - 2.1 7.5 7.4 2.6 7.2 1.0 2.6 2 1 1 3 3 3 0 Sensor protein DegS YlqD PF11068.3 AIF84005.1 - 2.5 8.1 12.4 2 8.4 1.4 2.1 2 0 0 2 2 2 0 YlqD protein Snapin_Pallidin PF14712.1 AIF84005.1 - 2.7 8.3 8.8 1.6 9.0 1.1 2.3 2 0 0 2 2 2 0 Snapin/Pallidin FlaC_arch PF05377.6 AIF84005.1 - 2.7 7.9 7.1 1.2 9.0 1.4 2.9 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) Kinetocho_Slk19 PF12709.2 AIF84005.1 - 3 7.9 10.4 16 5.6 0.2 3.4 2 2 0 2 2 2 0 Central kinetochore-associated Syntaxin PF00804.20 AIF84005.1 - 3.8 7.7 7.3 2.8 8.1 2.1 2.3 1 1 1 2 2 2 0 Syntaxin Mnd1 PF03962.10 AIF84005.1 - 3.9 7.0 14.4 6.5 6.3 2.1 2.1 1 1 0 2 2 2 0 Mnd1 family PspA_IM30 PF04012.7 AIF84005.1 - 4.2 6.6 25.9 0.97 8.7 4.4 2.1 1 1 1 2 2 2 0 PspA/IM30 family FliL PF03748.9 AIF84005.1 - 4.3 7.3 6.1 0.97 9.4 0.2 2.5 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL FlxA PF14282.1 AIF84005.1 - 4.3 7.3 14.0 0.69 9.8 1.5 2.6 2 1 0 2 2 2 0 FlxA-like protein FUSC PF04632.7 AIF84005.1 - 4.8 5.4 14.9 6 5.1 10.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2205 PF10224.4 AIF84005.1 - 5 6.7 11.0 2.7 7.6 1.6 3.1 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) CcmH PF03918.9 AIF84005.1 - 5.5 5.9 8.4 14 4.6 0.7 2.4 1 1 1 2 2 2 0 Cytochrome C biogenesis protein Med21 PF11221.3 AIF84005.1 - 7.6 6.4 13.0 0.25 11.2 0.4 2.7 1 1 2 3 3 3 0 Subunit 21 of Mediator complex DUF4391 PF14335.1 AIF84005.1 - 7.7 5.8 8.6 3.5 6.9 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4391) NTR2 PF15458.1 AIF84005.1 - 7.8 5.6 13.3 1.5 8.0 5.0 2.2 1 1 2 3 3 3 0 Nineteen complex-related protein 2 Reo_sigmaC PF04582.7 AIF84005.1 - 8.1 5.5 12.9 4.8 6.2 3.5 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein HAUS6_N PF14661.1 AIF84005.1 - 8.3 5.6 17.4 3 7.1 4.5 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Spc24 PF08286.6 AIF84005.1 - 9.1 6.0 12.3 11 5.8 1.1 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Rootletin PF15035.1 AIF84005.1 - 9.8 6.1 15.6 14 5.6 2.8 2.8 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DMPK_coil PF08826.5 AIF84005.1 - 9.9 6.1 13.3 0.22 11.4 3.0 2.5 2 1 1 3 3 2 0 DMPK coiled coil domain like Prok-RING_1 PF14446.1 AIF84006.1 - 0.0073 16.0 2.8 0.0093 15.6 1.9 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.24 AIF84006.1 - 0.04 13.6 4.5 0.052 13.2 3.1 1.2 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 AIF84006.1 - 0.042 13.5 5.4 0.061 13.0 3.8 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHF5 PF03660.9 AIF84006.1 - 0.047 13.7 0.9 0.057 13.4 0.6 1.2 1 0 0 1 1 1 0 PHF5-like protein DUF2180 PF09947.4 AIF84006.1 - 0.071 12.8 0.8 0.093 12.5 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-RING_2 PF13639.1 AIF84006.1 - 0.095 12.5 3.6 0.12 12.2 2.5 1.2 1 0 0 1 1 1 0 Ring finger domain Colicin_D PF11429.3 AIF84006.1 - 0.13 12.4 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Colicin D zf-C3HC4_3 PF13920.1 AIF84006.1 - 0.15 11.7 2.8 0.2 11.3 2.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 AIF84006.1 - 0.43 10.7 6.5 2.9 8.1 0.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2175 PF09943.4 AIF84006.1 - 1.1 9.3 4.4 1.3 9.0 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) PDH PF02153.12 AIF84007.1 - 3.1e-17 62.3 0.9 4.3e-17 61.8 0.6 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 AIF84007.1 - 3.8e-07 30.0 0.1 6.6e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AIF84007.1 - 4.6e-05 23.7 0.5 0.0014 18.9 0.1 2.7 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.14 AIF84007.1 - 5.2e-05 23.6 0.6 0.00038 20.9 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain NAD_Gly3P_dh_N PF01210.18 AIF84007.1 - 0.00019 21.1 2.3 0.00025 20.8 0.5 2.0 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding_2 PF13380.1 AIF84007.1 - 0.00024 21.2 0.1 0.0014 18.8 0.1 2.1 1 1 1 2 2 2 1 CoA binding domain Rossmann-like PF10727.4 AIF84007.1 - 0.00091 18.9 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_10 PF13460.1 AIF84007.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 AIF84007.1 - 0.016 14.6 0.1 0.053 12.8 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 AIF84007.1 - 0.029 14.9 0.5 0.1 13.1 0.2 2.1 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NmrA PF05368.8 AIF84007.1 - 0.034 13.3 0.3 2.1 7.5 0.0 2.3 1 1 1 2 2 2 0 NmrA-like family DapB_N PF01113.15 AIF84007.1 - 0.044 13.7 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 AIF84007.1 - 0.15 11.8 1.1 5.3 6.8 0.8 2.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.11 AIF84007.1 - 0.34 10.3 1.6 1.8 7.9 0.2 2.5 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Aminotran_1_2 PF00155.16 AIF84008.1 - 4.5e-54 183.7 0.0 5.8e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.16 AIF84008.1 - 1.4e-10 41.0 2.0 1.4e-10 41.0 1.4 2.0 2 0 0 2 2 2 1 Chorismate mutase type II Beta_elim_lyase PF01212.16 AIF84008.1 - 2.6e-10 39.9 0.0 5.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AIF84008.1 - 6.6e-10 38.2 0.0 1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AIF84008.1 - 1.1e-09 37.0 0.0 1.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AIF84008.1 - 8.2e-06 25.0 0.0 5.9e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family SurA_N PF09312.6 AIF84008.1 - 0.012 15.4 1.4 0.18 11.6 0.5 2.5 2 0 0 2 2 2 0 SurA N-terminal domain Chorismate_synt PF01264.16 AIF84009.1 - 3.8e-140 466.2 0.0 4.4e-140 466.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase EPSP_synthase PF00275.15 AIF84010.1 - 2.9e-108 362.0 0.4 3.4e-108 361.7 0.3 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GHMP_kinases_N PF00288.21 AIF84011.1 - 9.8e-12 44.7 0.5 2.6e-11 43.3 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AIF84011.1 - 1.1e-05 25.5 0.1 3.9e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal Shikimate_dh_N PF08501.6 AIF84012.1 - 1.3e-30 105.2 0.0 2.6e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AIF84012.1 - 8.1e-15 55.1 0.1 1.5e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AIF84012.1 - 8.1e-05 21.7 0.2 0.00013 21.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase OCD_Mu_crystall PF02423.10 AIF84012.1 - 0.0001 21.2 0.3 0.00014 20.7 0.2 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 AIF84012.1 - 0.00083 19.7 1.4 0.002 18.4 1.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GARS_N PF02844.10 AIF84012.1 - 0.0075 16.7 0.2 0.019 15.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain DHquinase_I PF01487.10 AIF84013.1 - 8.4e-50 169.4 0.0 9.5e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF3268 PF11672.3 AIF84015.1 - 0.089 12.8 0.3 0.21 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) N6_N4_Mtase PF01555.13 AIF84016.1 - 5.4e-34 117.6 0.0 6.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 AIF84016.1 - 9.2e-11 41.8 0.0 0.00015 21.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84016.1 - 0.00012 21.7 0.0 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF84016.1 - 0.0008 19.8 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84016.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 AIF84016.1 - 0.051 13.1 0.0 2.8 7.4 0.0 2.4 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 CMAS PF02353.15 AIF84016.1 - 0.082 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 AIF84016.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.10 AIF84016.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DHQS PF01959.11 AIF84017.1 - 2.9e-114 381.4 1.3 3.4e-114 381.2 0.9 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase (EC 4.6.1.3) Helicase_RecD PF05127.9 AIF84017.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Helicase NMO PF03060.10 AIF84017.1 - 0.057 12.5 0.2 0.15 11.2 0.1 1.7 1 0 0 1 1 1 0 Nitronate monooxygenase Hom_end_hint PF05203.11 AIF84017.1 - 0.082 12.6 0.1 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint DeoC PF01791.4 AIF84018.1 - 1.7e-46 158.4 0.0 2e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase PEP_mutase PF13714.1 AIF84018.1 - 0.002 17.4 0.2 0.028 13.6 0.1 2.2 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ThiG PF05690.9 AIF84018.1 - 0.0024 16.9 4.4 0.0072 15.4 0.4 3.0 3 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 AIF84018.1 - 0.022 14.0 0.1 0.095 11.9 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF561 PF04481.7 AIF84018.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) V4R PF02830.13 AIF84019.1 - 1.1e-10 41.1 0.9 1.7e-10 40.5 0.7 1.3 1 0 0 1 1 1 1 V4R domain AP_endonuc_2 PF01261.19 AIF84021.1 - 8.1e-30 103.7 0.0 1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DNA_primase_lrg PF04104.9 AIF84022.1 - 3.4e-29 101.9 0.1 6.5e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DNA_primase_S PF01896.14 AIF84023.1 - 6.3e-14 52.0 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit FAM72 PF14976.1 AIF84023.1 - 0.0065 16.3 0.1 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 FAM72 protein DUF4503 PF14951.1 AIF84023.1 - 0.016 13.3 0.1 0.024 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) TF_Zn_Ribbon PF08271.7 AIF84023.1 - 0.094 12.0 0.5 0.24 10.7 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Ribosomal_L37ae PF01780.14 AIF84023.1 - 0.097 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family OrfB_Zn_ribbon PF07282.6 AIF84023.1 - 0.098 12.3 1.7 0.14 11.8 0.4 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain NOB1_Zn_bind PF08772.6 AIF84023.1 - 0.25 11.1 2.4 7.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 AIF84023.1 - 1.7 8.5 6.2 4.3 7.2 4.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon UPF0182 PF03699.8 AIF84024.1 - 1.9e-36 125.3 4.7 1.9e-36 125.3 3.2 3.2 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0182) GATase PF00117.23 AIF84025.1 - 8e-23 80.8 0.0 8.9e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIF84025.1 - 5e-11 42.4 0.0 1.7e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 TPR_11 PF13414.1 AIF84026.1 - 3.3e-23 81.1 10.4 4.7e-12 45.3 2.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 AIF84026.1 - 1.5e-14 54.1 11.3 3.1e-06 27.7 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AIF84026.1 - 2.2e-14 52.3 13.9 3.6e-07 29.5 1.3 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AIF84026.1 - 8.9e-14 50.2 11.5 3.3e-05 23.4 0.7 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AIF84026.1 - 2.7e-12 45.8 8.1 7.1e-05 22.6 0.9 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AIF84026.1 - 7.7e-11 41.6 5.5 0.0011 19.4 0.6 4.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 AIF84026.1 - 1.1e-09 38.4 8.6 0.00014 22.1 0.9 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 AIF84026.1 - 1.8e-09 37.3 0.5 1.2e-07 31.4 0.0 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AIF84026.1 - 2.9e-09 36.7 9.8 1.3e-08 34.6 1.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIF84026.1 - 1.7e-07 30.5 10.5 0.0001 21.8 2.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AIF84026.1 - 5.1e-05 23.4 9.7 2 9.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AIF84026.1 - 0.0001 21.8 7.9 0.72 9.7 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 AIF84026.1 - 0.0045 17.0 6.7 0.02 15.0 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 AIF84026.1 - 0.0055 15.8 0.6 0.0055 15.8 0.4 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Peptidase_C39_2 PF13529.1 AIF84026.1 - 0.016 15.5 0.2 0.05 13.9 0.0 1.9 2 1 1 3 3 3 0 Peptidase_C39 like family Transpep_BrtH PF14399.1 AIF84026.1 - 0.04 13.2 1.3 0.72 9.0 0.0 2.8 1 1 0 2 2 2 0 NlpC/p60-like transpeptidase TPR_10 PF13374.1 AIF84026.1 - 4.9 7.2 7.1 17 5.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 AIF84026.1 - 7.2 7.3 12.1 2.7 8.7 2.5 3.4 3 0 0 3 3 3 0 Sel1 repeat ABM PF03992.11 AIF84027.1 - 1.3e-14 54.0 0.0 1.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase COX5A PF02284.11 AIF84027.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Aldo_ket_red PF00248.16 AIF84028.1 - 9.4e-32 109.9 0.0 1.7e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family Tmemb_14 PF03647.8 AIF84029.1 - 0.78 10.1 10.6 1.7 9.1 2.5 3.1 3 1 0 3 3 3 0 Transmembrane proteins 14C HTH_45 PF14947.1 AIF84030.1 - 3.1e-09 36.5 0.0 3.4e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix AAA_assoc_C PF09821.4 AIF84030.1 - 0.024 14.8 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal AAA-associated domain Rio2_N PF09202.6 AIF84030.1 - 0.032 14.3 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Rio2, N-terminal DUF2513 PF10711.4 AIF84030.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Hypothetical protein (DUF2513) UbiA PF01040.13 AIF84031.1 - 2.3e-31 108.9 22.6 3e-31 108.6 15.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3989 PF13150.1 AIF84031.1 - 0.93 8.9 2.6 2.5 7.6 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) AsnC_trans_reg PF01037.16 AIF84032.1 - 3.6e-10 39.3 0.0 4e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 AIF84032.1 - 0.027 14.7 0.1 6.3 7.2 0.0 2.1 2 0 0 2 2 2 0 ACT domain DUF2203 PF09969.4 AIF84033.1 - 4e-35 120.6 0.1 4.6e-35 120.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) Na_H_Exchanger PF00999.16 AIF84034.1 - 4.6e-70 236.0 49.7 5.4e-70 235.8 34.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GDE_C PF06202.9 AIF84035.1 - 1.3e-37 129.3 0.0 2.4e-37 128.5 0.0 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 AIF84035.1 - 2.3e-11 42.6 0.0 3.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Glyco_hydro_100 PF12899.2 AIF84035.1 - 9.3e-08 30.8 0.1 0.0014 17.1 0.0 2.2 2 0 0 2 2 2 2 Alkaline and neutral invertase DUF608 PF04685.8 AIF84035.1 - 3.9e-07 29.1 1.3 1.1e-05 24.2 1.7 2.5 2 1 0 2 2 2 1 Protein of unknown function, DUF608 Trehalase PF01204.13 AIF84035.1 - 1.4e-05 23.9 0.1 3.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Trehalase Type_III_YscG PF09477.5 AIF84035.1 - 0.0012 18.9 0.1 0.0048 16.9 0.0 1.9 2 0 0 2 2 2 1 Bacterial type II secretion system chaperone protein (type_III_yscG) Fis1_TPR_C PF14853.1 AIF84035.1 - 0.091 12.6 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Osmo_MPGsynth PF09488.5 AIF84036.1 - 2.4e-155 516.9 0.0 2.7e-155 516.7 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) zf-C4_Topoisom PF01396.14 AIF84037.1 - 0.0057 16.1 1.2 0.0084 15.5 0.8 1.3 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger C1_3 PF07649.7 AIF84037.1 - 0.027 14.4 3.6 0.027 14.4 2.5 1.7 2 0 0 2 2 2 0 C1-like domain Zn_Tnp_IS1595 PF12760.2 AIF84037.1 - 0.028 14.2 0.3 0.041 13.6 0.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HNOBA PF07701.9 AIF84037.1 - 0.073 12.2 0.1 0.079 12.1 0.0 1.0 1 0 0 1 1 1 0 Heme NO binding associated Zn-ribbon_8 PF09723.5 AIF84037.1 - 0.15 12.0 3.6 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 AIF84037.1 - 0.24 10.9 4.8 0.55 9.7 3.3 1.6 1 1 0 1 1 1 0 A2L zinc ribbon domain TFIIS_C PF01096.13 AIF84037.1 - 0.46 10.1 3.2 8.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Cytochrom_c3_2 PF14537.1 AIF84037.1 - 1 9.7 3.8 0.46 10.8 0.6 1.7 1 1 1 2 2 2 0 Cytochrome c3 C1_2 PF03107.11 AIF84037.1 - 2.7 8.1 7.9 0.39 10.8 2.7 1.6 1 1 0 1 1 1 0 C1 domain TF_Zn_Ribbon PF08271.7 AIF84037.1 - 3.6 6.9 12.6 0.06 12.6 3.7 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding UPF0086 PF01868.11 AIF84038.1 - 0.0022 17.5 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function UPF0086 DUF4147 PF13660.1 AIF84039.1 - 3.3e-82 275.2 2.0 5.1e-82 274.5 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 AIF84039.1 - 8.7e-31 106.2 1.6 1.7e-30 105.2 1.1 1.5 1 0 0 1 1 1 1 MOFRL family AIRC PF00731.15 AIF84039.1 - 0.98 8.6 6.5 2 7.6 0.3 3.3 3 1 0 4 4 4 0 AIR carboxylase BPL_LplA_LipB PF03099.14 AIF84040.1 - 9.6e-22 77.3 0.1 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.7 AIF84040.1 - 8.9e-15 54.0 0.2 2e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.12 AIF84040.1 - 3.8e-06 26.4 1.1 7.6e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain HTH_24 PF13412.1 AIF84040.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.1 AIF84040.1 - 0.0053 16.8 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.15 AIF84040.1 - 0.0093 16.0 0.1 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_1 PF00126.22 AIF84040.1 - 0.11 12.2 0.1 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.1 AIF84040.1 - 0.12 11.9 0.2 0.28 10.7 0.2 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Fe_dep_repress PF01325.14 AIF84040.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF2087 PF09860.4 AIF84041.1 - 0.0043 16.7 0.2 0.0099 15.6 0.1 1.5 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2087) THF_DHG_CYH PF00763.18 AIF84041.1 - 0.058 13.4 0.2 0.077 13.0 0.1 1.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Synaptobrevin PF00957.16 AIF84041.1 - 0.088 12.4 0.3 0.13 11.8 0.1 1.3 1 1 0 1 1 1 0 Synaptobrevin MMR_HSR1_C PF08438.5 AIF84042.1 - 5.2e-34 116.7 0.0 1.4e-33 115.3 0.0 1.7 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AIF84042.1 - 1.1e-16 60.8 0.0 3.6e-16 59.1 0.0 1.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase TGS PF02824.16 AIF84042.1 - 3.7e-10 39.4 0.0 6.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 AIF84042.1 - 9.1e-08 31.5 0.1 4.7e-06 25.9 0.2 2.9 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AIF84042.1 - 0.00017 21.4 0.0 0.043 13.6 0.0 2.4 1 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 AIF84042.1 - 0.0032 16.9 0.2 1.4 8.2 0.1 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Imm31 PF15595.1 AIF84045.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 31 CoA_binding_2 PF13380.1 AIF84047.1 - 4.9e-38 129.8 0.3 5.6e-38 129.6 0.2 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 AIF84047.1 - 2.7e-07 31.0 0.4 5e-07 30.1 0.1 1.5 2 0 0 2 2 2 1 CoA binding domain TroA PF01297.12 AIF84047.1 - 0.015 14.5 0.0 0.03 13.5 0.0 1.5 2 0 0 2 2 2 0 Periplasmic solute binding protein family Fmp27 PF10344.4 AIF84048.1 - 0.026 12.2 0.9 0.034 11.8 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 cobW PF02492.14 AIF84048.1 - 0.078 12.4 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GATase_2 PF00310.16 AIF84051.1 - 5.2e-21 74.7 0.1 1.9e-10 39.9 0.0 3.1 2 1 1 3 3 3 3 Glutamine amidotransferases class-II GATase_6 PF13522.1 AIF84051.1 - 1.4e-15 57.3 0.0 2.5e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AIF84051.1 - 1.7e-13 50.4 0.0 2.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 AIF84051.1 - 6.6e-09 35.5 0.1 1.5e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 AIF84051.1 - 2.4e-06 26.4 0.0 3.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AIRS_C PF02769.17 AIF84052.1 - 8.7e-46 155.7 0.6 1.1e-21 77.4 0.0 2.2 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AIF84052.1 - 1e-38 131.4 2.5 6.5e-23 80.7 0.3 2.7 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain GATase_5 PF13507.1 AIF84053.1 - 2.2e-44 151.3 0.0 3e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.9 AIF84053.1 - 2.1e-08 33.8 0.0 9.8e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 AIF84053.1 - 2.6e-08 33.4 0.0 7e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 DJ-1/PfpI family GATase PF00117.23 AIF84053.1 - 1.4e-07 31.1 0.0 2.6e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 AIF84053.1 - 3.8e-05 23.0 0.0 0.0002 20.6 0.0 1.9 2 0 0 2 2 2 1 Putative amidotransferase SNO PF01174.14 AIF84053.1 - 0.00068 19.3 0.0 0.0017 18.0 0.0 1.6 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 AIF84053.1 - 0.0039 16.6 0.1 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CBS PF00571.23 AIF84054.1 - 5.4e-32 109.3 5.7 1.2e-16 60.2 0.1 2.6 3 0 0 3 3 3 2 CBS domain PurS PF02700.9 AIF84055.1 - 2.3e-19 69.1 0.4 2.6e-19 68.9 0.3 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase DpnD-PcfM PF14207.1 AIF84055.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 DpnD/PcfM-like protein Nitroreductase PF00881.19 AIF84056.1 - 4.7e-21 75.3 0.0 6.9e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family ABC2_membrane PF01061.19 AIF84057.1 - 3e-16 59.2 23.1 4.1e-16 58.7 16.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AIF84057.1 - 1e-11 44.4 20.2 1e-11 44.4 14.0 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein Phage_holin_1 PF04531.8 AIF84057.1 - 0.0048 16.9 0.7 0.01 15.8 0.1 1.9 2 0 0 2 2 2 1 Bacteriophage holin ABC_tran PF00005.22 AIF84058.1 - 8e-28 97.4 0.0 1.2e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF84058.1 - 2.2e-09 37.7 0.0 5.2e-06 26.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain UPF0079 PF02367.12 AIF84058.1 - 0.00025 20.6 0.1 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 AIF84058.1 - 0.0021 17.5 0.2 0.006 16.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 AIF84058.1 - 0.0047 16.1 0.0 0.24 10.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 AIF84058.1 - 0.013 15.1 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 AIF84058.1 - 0.017 15.0 0.0 0.15 11.9 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 AIF84058.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain MutS_V PF00488.16 AIF84058.1 - 0.064 12.6 0.1 0.77 9.1 0.0 2.0 2 0 0 2 2 2 0 MutS domain V AAA PF00004.24 AIF84058.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AIF84058.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AIF84058.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_M50 PF02163.17 AIF84060.1 - 4.9e-29 100.6 0.0 1.7e-28 98.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.1 AIF84060.1 - 0.014 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF3099 PF11298.3 AIF84060.1 - 0.21 11.3 4.0 4.4 7.1 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) SnoaL_2 PF12680.2 AIF84061.1 - 5.1e-10 39.6 0.0 6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.7 AIF84061.1 - 1.4e-05 25.1 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Lumazine_bd PF12870.2 AIF84061.1 - 0.08 12.9 0.2 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Lumazine-binding domain HTH_24 PF13412.1 AIF84062.1 - 8.9e-19 66.6 1.2 5e-09 35.3 0.0 3.1 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF84062.1 - 1.2e-17 63.1 1.5 9e-10 37.9 0.2 3.0 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain HTH_5 PF01022.15 AIF84062.1 - 3e-05 23.5 0.1 0.0001 21.9 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_9 PF08221.6 AIF84062.1 - 7.4e-05 22.5 0.4 0.0092 15.8 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain MarR_2 PF12802.2 AIF84062.1 - 0.00012 21.6 0.3 0.17 11.5 0.0 2.8 2 0 0 2 2 2 2 MarR family HTH_IclR PF09339.5 AIF84062.1 - 0.00029 20.3 0.5 0.086 12.4 0.0 2.8 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_20 PF12840.2 AIF84062.1 - 0.00066 19.4 0.3 0.12 12.1 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Mga PF08280.6 AIF84062.1 - 0.0036 17.0 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HMA PF00403.21 AIF84062.1 - 0.005 16.9 0.4 0.012 15.7 0.3 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain LexA_DNA_bind PF01726.11 AIF84062.1 - 0.012 15.1 0.1 0.38 10.3 0.0 2.4 2 0 0 2 2 2 0 LexA DNA binding domain TrmB PF01978.14 AIF84062.1 - 0.048 13.3 0.1 4.9 6.9 0.0 2.8 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB SnoaL_2 PF12680.2 AIF84063.1 - 9.7e-13 48.4 0.0 1.1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 AIF84063.1 - 5.8e-07 29.1 0.0 5.3e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 AIF84063.1 - 0.00027 21.1 0.0 0.00033 20.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd PF12870.2 AIF84063.1 - 0.0017 18.4 0.1 0.0027 17.7 0.1 1.5 1 1 0 1 1 1 1 Lumazine-binding domain LEH PF07858.7 AIF84063.1 - 0.022 14.7 0.1 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain HTH_24 PF13412.1 AIF84064.1 - 1.5e-18 65.9 1.6 2.7e-09 36.2 0.1 2.7 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF84064.1 - 2.6e-18 65.2 0.3 1.9e-11 43.2 0.5 2.7 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_5 PF01022.15 AIF84064.1 - 5.5e-06 25.9 0.1 7.8e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF84064.1 - 2.2e-05 24.0 0.2 0.068 12.8 0.0 2.7 2 1 0 2 2 2 2 MarR family HTH_20 PF12840.2 AIF84064.1 - 0.00012 21.8 0.0 0.0029 17.3 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Mga PF08280.6 AIF84064.1 - 0.0016 18.1 0.0 0.0064 16.2 0.0 2.1 2 1 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HMA PF00403.21 AIF84064.1 - 0.0046 17.0 0.7 0.0092 16.1 0.5 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Mga PF05043.8 AIF84064.1 - 0.0076 16.4 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 1 Mga helix-turn-helix domain TFIIE_alpha PF02002.12 AIF84064.1 - 0.017 14.5 0.1 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_9 PF08221.6 AIF84064.1 - 0.062 13.1 0.3 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_IclR PF09339.5 AIF84064.1 - 0.063 12.8 0.2 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain SnoaL PF07366.7 AIF84065.1 - 1.5e-25 89.2 0.6 2e-25 88.8 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AIF84065.1 - 7.1e-18 64.8 0.1 1e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.7 AIF84065.1 - 5.6e-06 26.3 0.3 6.3e-06 26.1 0.2 1.0 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain HD_3 PF13023.1 AIF84065.1 - 0.052 13.2 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 HD domain Methyltransf_11 PF08241.7 AIF84066.1 - 2.3e-19 69.6 0.0 4.4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84066.1 - 9.7e-19 67.6 0.0 1.2e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84066.1 - 1.1e-15 57.5 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84066.1 - 8e-15 55.0 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84066.1 - 2e-14 54.0 0.0 3.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84066.1 - 1.9e-10 41.0 0.0 3.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF84066.1 - 6.5e-08 31.9 0.0 8.7e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AIF84066.1 - 1.6e-07 31.3 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIF84066.1 - 3.4e-06 26.3 0.0 4.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 AIF84066.1 - 7.1e-06 25.3 0.0 9.6e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 AIF84066.1 - 1.1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 AIF84066.1 - 3.9e-05 22.1 0.0 5e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.13 AIF84066.1 - 0.00032 20.0 0.0 0.1 11.8 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.10 AIF84066.1 - 0.00054 19.6 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase TPMT PF05724.6 AIF84066.1 - 0.0088 15.4 0.0 0.027 13.9 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 AIF84066.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AIF84066.1 - 0.018 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.13 AIF84066.1 - 0.019 14.4 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 DNA methylase RrnaAD PF00398.15 AIF84066.1 - 0.02 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 AIF84066.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Lumazine_bd PF12870.2 AIF84066.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Lumazine-binding domain MetW PF07021.7 AIF84066.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF3353 PF11833.3 AIF84067.1 - 0.0012 18.4 1.4 0.0018 17.7 1.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3353) Yip1 PF04893.12 AIF84067.1 - 0.051 13.0 8.7 0.063 12.7 6.0 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4153 PF13687.1 AIF84067.1 - 0.29 10.6 6.7 0.17 11.4 3.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) DUF4383 PF14325.1 AIF84067.1 - 1.6 8.7 7.4 7.7 6.5 5.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) Beta-Casp PF10996.3 AIF84069.1 - 7.4e-28 97.0 0.0 1.8e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 AIF84069.1 - 1e-16 61.1 0.1 2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 AIF84069.1 - 1.9e-14 53.1 0.0 4.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 AIF84069.1 - 2.1e-13 50.2 0.1 8.4e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AIF84069.1 - 0.023 14.4 0.0 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Herpes_UL1 PF05259.6 AIF84070.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein L HisKA_3 PF07730.8 AIF84071.1 - 0.0034 17.6 9.7 0.027 14.8 0.1 3.8 1 1 2 3 3 3 2 Histidine kinase Talin_middle PF09141.5 AIF84071.1 - 0.011 15.4 2.0 0.011 15.4 1.4 1.8 1 1 1 2 2 2 0 Talin, middle domain ANTAR PF03861.9 AIF84071.1 - 0.022 14.3 0.6 0.28 10.7 0.1 2.6 1 1 1 2 2 2 0 ANTAR domain DUF746 PF05344.6 AIF84071.1 - 0.041 13.4 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Transpep_BrtH PF14399.1 AIF84071.1 - 0.18 11.0 3.4 0.085 12.1 0.3 1.8 1 1 0 2 2 2 0 NlpC/p60-like transpeptidase DUF948 PF06103.6 AIF84071.1 - 0.25 11.2 3.7 0.42 10.5 1.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RPA_C PF08784.6 AIF84071.1 - 0.3 11.5 3.7 12 6.3 0.1 2.5 1 1 1 2 2 2 0 Replication protein A C terminal DUF2203 PF09969.4 AIF84071.1 - 0.73 10.0 5.6 8.5 6.6 3.9 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.6 AIF84071.1 - 0.91 9.9 4.6 1.6 9.1 1.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.1 AIF84071.1 - 1.1 9.3 5.2 13 5.8 3.6 2.4 1 1 0 1 1 1 0 Syntaxin-like protein SYF2 PF08231.7 AIF84071.1 - 1.3 9.1 7.7 3.5 7.7 5.3 1.9 1 1 0 1 1 1 0 SYF2 splicing factor DUF2390 PF09523.5 AIF84071.1 - 6.3 7.0 7.8 27 5.0 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2390) UPF0147 PF03685.8 AIF84072.1 - 2.9e-22 78.3 3.4 3.3e-22 78.1 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) DUF1216 PF06746.6 AIF84072.1 - 0.052 13.3 7.6 0.68 9.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) YtzH PF14165.1 AIF84072.1 - 0.081 13.1 2.2 0.54 10.5 0.8 2.2 1 1 2 3 3 3 0 YtzH-like protein DUF3461 PF11944.3 AIF84072.1 - 0.11 12.3 1.7 0.87 9.4 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) ATP-cone PF03477.11 AIF84072.1 - 0.18 12.2 1.2 0.38 11.2 0.8 1.5 1 1 1 2 2 2 0 ATP cone domain TMV_coat PF00721.16 AIF84072.1 - 0.24 11.3 2.1 0.25 11.2 0.6 1.6 1 1 1 2 2 2 0 Virus coat protein (TMV like) Prp18 PF02840.10 AIF84072.1 - 0.28 11.0 3.5 0.47 10.2 1.0 1.8 1 1 1 2 2 2 0 Prp18 domain Rgp1 PF08737.5 AIF84072.1 - 0.48 9.4 3.6 0.55 9.2 2.5 1.1 1 0 0 1 1 1 0 Rgp1 PadR PF03551.9 AIF84073.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_45 PF14947.1 AIF84073.1 - 0.046 13.5 0.0 0.073 12.8 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix zf-C2H2_2 PF12756.2 AIF84074.1 - 0.0019 18.2 0.1 0.0022 18.0 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF3505 PF12013.3 AIF84074.1 - 0.055 13.6 0.1 0.06 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) AKAP95 PF04988.7 AIF84074.1 - 0.056 13.2 0.3 0.07 12.9 0.2 1.1 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) RMP PF14996.1 AIF84074.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Retinal Maintenance Usp PF00582.21 AIF84075.1 - 3.1e-36 124.6 0.2 3.4e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Universal stress protein family PucR PF07905.6 AIF84075.1 - 0.00052 19.5 0.0 0.0008 18.9 0.0 1.2 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family ETF PF01012.16 AIF84075.1 - 0.005 16.5 0.2 0.069 12.8 0.1 2.2 1 1 0 1 1 1 1 Electron transfer flavoprotein domain Oxidored_nitro PF00148.14 AIF84075.1 - 0.0095 14.6 0.1 0.011 14.4 0.1 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase PGM_PMM_I PF02878.11 AIF84075.1 - 0.062 12.7 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Na_Ca_ex PF01699.19 AIF84077.1 - 9.2e-26 90.1 30.8 1.6e-13 50.4 7.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Methyltransf_26 PF13659.1 AIF84078.1 - 0.00024 21.1 0.1 0.0017 18.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84078.1 - 0.0047 17.4 0.1 0.011 16.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84078.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84078.1 - 0.022 14.3 0.3 0.04 13.4 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 AIF84078.1 - 0.06 12.7 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Zn_Tnp_IS1595 PF12760.2 AIF84079.1 - 0.0026 17.5 1.4 0.0032 17.2 1.0 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.6 AIF84079.1 - 0.13 12.0 0.2 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) zf-C2H2 PF00096.21 AIF84079.1 - 0.26 11.7 1.5 0.51 10.7 1.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 AIF84079.1 - 0.26 11.2 2.0 0.43 10.5 0.3 1.9 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 AIF84079.1 - 0.32 10.5 4.9 0.69 9.4 3.4 1.6 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit PCP PF02429.10 AIF84080.1 - 0.034 14.2 2.8 0.036 14.1 2.0 1.0 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein DUF883 PF05957.8 AIF84080.1 - 0.068 13.5 4.1 0.11 12.9 2.9 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Phasin_2 PF09361.5 AIF84080.1 - 0.085 12.8 6.7 0.11 12.5 4.6 1.4 1 1 0 1 1 1 0 Phasin protein ATP-synt_B PF00430.13 AIF84080.1 - 0.12 12.1 13.3 0.14 11.9 9.2 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) EspB PF05802.6 AIF84080.1 - 0.13 11.1 4.8 0.14 11.0 3.3 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein Borrelia_P83 PF05262.6 AIF84080.1 - 0.16 10.2 12.2 0.17 10.1 8.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein MT0933_antitox PF14013.1 AIF84080.1 - 0.48 10.5 16.4 2.6 8.1 5.1 2.4 1 1 1 2 2 2 0 MT0933-like antitoxin protein Actino_peptide PF14408.1 AIF84080.1 - 0.49 10.3 1.8 1.1 9.1 0.4 1.9 1 1 1 2 2 2 0 Ribosomally synthesized peptide in actinomycetes DUF4629 PF15442.1 AIF84080.1 - 1.1 9.3 9.4 1.2 9.3 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) ISG65-75 PF11727.3 AIF84080.1 - 3.7 6.5 10.9 4.3 6.3 7.5 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein YtxH PF12732.2 AIF84080.1 - 4.3 7.7 11.6 26 5.2 8.1 1.9 1 1 0 1 1 1 0 YtxH-like protein FIVAR PF07554.8 AIF84080.1 - 6.3 7.1 9.4 13 6.1 2.3 2.2 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain DUF2570 PF10828.3 AIF84080.1 - 8.3 6.0 6.4 9.5 5.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4407 PF14362.1 AIF84080.1 - 9 5.1 8.6 11 4.9 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2229 PF09989.4 AIF84080.1 - 9.7 5.5 6.6 11 5.4 4.6 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) CrtC PF07143.6 AIF84082.1 - 9.9e-16 57.9 1.2 1.2e-15 57.6 0.8 1.1 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Svf1 PF08622.5 AIF84082.1 - 0.0066 15.4 0.0 0.0086 15.1 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 AIF84083.1 - 0.034 13.4 0.9 0.043 13.1 0.6 1.1 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) ABC2_membrane_4 PF12730.2 AIF84084.1 - 0.023 13.8 0.3 0.029 13.5 0.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1113 PF06541.6 AIF84084.1 - 0.032 13.9 1.2 0.039 13.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1113) CbtB PF09489.5 AIF84084.1 - 0.1 12.5 0.1 3 7.8 0.0 2.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) P12 PF12669.2 AIF84084.1 - 0.49 10.6 3.4 1.7 8.8 0.1 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family VPEP PF07589.6 AIF84084.1 - 1.3 8.9 4.0 17 5.5 0.2 2.3 2 0 0 2 2 2 0 PEP-CTERM motif DUF2892 PF11127.3 AIF84084.1 - 4.8 7.0 5.4 3.5 7.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Glyoxalase_2 PF12681.2 AIF84085.1 - 3.8e-14 53.2 0.0 4.4e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF84085.1 - 2.2e-08 34.1 0.0 4.2e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 AIF84085.1 - 0.0048 16.9 0.0 0.0097 15.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4520 PF15016.1 AIF84085.1 - 0.12 11.9 0.0 0.75 9.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4520) Glyoxalase_3 PF13468.1 AIF84085.1 - 0.14 12.0 0.0 0.56 10.0 0.0 1.7 1 1 1 2 2 2 0 Glyoxalase-like domain DUF4256 PF14066.1 AIF84086.1 - 3.2e-39 134.1 0.1 3.5e-39 134.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4256) CoA_binding PF02629.14 AIF84090.1 - 4.4e-21 75.1 0.4 1.4e-20 73.6 0.3 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 AIF84090.1 - 2.5e-09 36.8 0.0 4.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.1 AIF84090.1 - 1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 AIF84090.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.17 AIF84090.1 - 0.018 15.5 0.0 0.05 14.1 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ATP-grasp_2 PF08442.5 AIF84091.1 - 1.3e-39 135.7 0.0 2.2e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 AIF84091.1 - 9.7e-14 51.2 1.2 1.7e-13 50.4 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 AIF84091.1 - 1e-13 51.0 0.1 1.9e-12 46.8 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AIF84091.1 - 4.5e-06 26.5 0.0 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 AIF84091.1 - 8e-05 22.0 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AIF84091.1 - 0.00024 20.4 0.0 0.0005 19.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Transp_cyt_pur PF02133.10 AIF84092.1 - 3.6e-29 101.5 37.4 5.5e-29 101.0 25.9 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ThiC PF01964.13 AIF84093.1 - 4.3e-176 585.5 0.2 4.9e-176 585.3 0.1 1.0 1 0 0 1 1 1 1 ThiC family Halo_GVPC PF05465.8 AIF84094.1 - 0.11 12.4 1.1 0.43 10.5 0.5 2.0 1 1 1 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat C6_DPF PF10170.4 AIF84095.1 - 0.0071 16.3 2.6 0.0074 16.3 1.8 1.1 1 0 0 1 1 1 1 Cysteine-rich domain PAAR_motif PF05488.8 AIF84095.1 - 0.12 12.4 0.5 0.11 12.5 0.3 1.1 1 0 0 1 1 1 0 PAAR motif DUF883 PF05957.8 AIF84096.1 - 0.069 13.5 0.5 0.084 13.2 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Phos_pyr_kin PF08543.7 AIF84097.1 - 4.9e-87 291.1 3.0 7e-87 290.7 2.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Aldolase_2 PF10120.4 AIF84097.1 - 3.3e-54 182.8 3.2 8.5e-54 181.4 0.3 2.3 3 0 0 3 3 3 1 Putative aldolase PfkB PF00294.19 AIF84097.1 - 6.1e-15 55.1 0.6 1.2e-14 54.1 0.2 1.5 2 0 0 2 2 2 1 pfkB family carbohydrate kinase NTP_transferase PF00483.18 AIF84098.1 - 1.8e-34 119.1 0.0 2.1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AIF84098.1 - 5.6e-12 46.0 0.0 7.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 AIF84098.1 - 6e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase IspD PF01128.14 AIF84098.1 - 0.0011 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_4 PF13562.1 AIF84099.1 - 4.2e-13 49.2 0.0 6.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Sugar nucleotidyl transferase Hexapep PF00132.19 AIF84099.1 - 0.00032 20.0 0.3 5.4 6.7 0.0 4.5 3 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) SHOCT PF09851.4 AIF84100.1 - 6.2e-08 31.8 0.2 9.4e-08 31.2 0.2 1.3 1 0 0 1 1 1 1 Short C-terminal domain FtsX PF02687.16 AIF84100.1 - 0.0087 15.8 3.0 0.011 15.4 2.1 1.1 1 0 0 1 1 1 1 FtsX-like permease family DUF1517 PF07466.6 AIF84100.1 - 0.05 12.5 0.0 0.073 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) DUF4381 PF14316.1 AIF84100.1 - 0.13 12.4 0.3 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TPPK_C PF12555.3 AIF84100.1 - 0.49 10.1 8.0 3.8 7.3 0.4 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Inhibitor_I9 PF05922.11 AIF84102.1 - 0.049 14.1 0.0 0.099 13.2 0.0 1.6 1 1 0 1 1 1 0 Peptidase inhibitor I9 Epimerase_2 PF02350.14 AIF84103.1 - 1.3e-50 172.1 0.0 1.6e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase 7TMR-DISM_7TM PF07695.6 AIF84104.1 - 0.065 12.8 5.5 0.16 11.5 3.8 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling GalP_UDP_transf PF01087.17 AIF84105.1 - 4.8e-13 49.5 0.0 6.3e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 AIF84105.1 - 9.5e-08 32.4 0.0 0.00072 20.0 0.0 2.5 3 0 0 3 3 3 2 HIT domain GalP_UDP_tr_C PF02744.12 AIF84105.1 - 5.2e-05 22.8 0.0 9.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 AIF84105.1 - 0.0007 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-Di19 PF05605.7 AIF84105.1 - 0.084 13.0 0.2 8.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 AIF84105.1 - 0.31 10.3 3.7 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SF-assemblin PF06705.6 AIF84106.1 - 0.051 12.7 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Metal_resist PF13801.1 AIF84106.1 - 0.058 13.3 0.1 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Heavy-metal resistance PhosphMutase PF10143.4 AIF84107.1 - 2.3e-44 151.0 0.1 3.4e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 AIF84107.1 - 8.2e-27 94.1 0.0 1.7e-26 93.1 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 AIF84107.1 - 0.0075 15.6 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4131 PF13567.1 AIF84108.1 - 0.033 13.5 0.0 0.033 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TPT PF03151.11 AIF84108.1 - 0.046 13.3 0.2 0.048 13.3 0.2 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family DUF4401 PF14351.1 AIF84108.1 - 0.067 12.1 0.2 0.07 12.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) P12 PF12669.2 AIF84108.1 - 0.087 13.0 0.2 0.9 9.7 0.0 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family PMP22_Claudin PF00822.15 AIF84108.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DZR PF12773.2 AIF84109.1 - 0.0068 16.1 1.3 0.0098 15.6 0.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon NOB1_Zn_bind PF08772.6 AIF84109.1 - 0.026 14.3 0.1 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF4379 PF14311.1 AIF84109.1 - 0.051 13.4 2.8 0.079 12.7 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4379) A2L_zn_ribbon PF08792.5 AIF84109.1 - 0.052 13.0 3.0 2.7 7.5 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 AIF84109.1 - 0.48 9.9 2.5 3.7 7.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF84109.1 - 0.78 9.0 5.7 4.4 6.6 0.9 2.3 1 1 1 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.19 AIF84109.1 - 1.1 9.1 5.0 3.7 7.5 3.5 1.7 1 1 0 1 1 1 0 B-box zinc finger RNA_POL_M_15KD PF02150.11 AIF84109.1 - 3.2 7.5 8.4 57 3.5 5.8 2.1 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit TFIIB PF00382.14 AIF84110.1 - 2.2e-26 91.4 3.9 9.2e-14 51.0 1.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AIF84110.1 - 1.7e-09 36.8 0.7 1.7e-09 36.8 0.5 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding zf-C4_Topoisom PF01396.14 AIF84110.1 - 0.0062 16.0 2.2 0.022 14.2 0.6 2.3 2 1 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.1 AIF84110.1 - 0.072 12.3 0.9 0.17 11.1 0.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Cyclin_N PF00134.18 AIF84110.1 - 0.099 12.2 3.9 0.14 11.6 1.0 2.1 1 1 2 3 3 3 0 Cyclin, N-terminal domain OrfB_Zn_ribbon PF07282.6 AIF84110.1 - 0.44 10.2 5.4 0.13 11.9 1.4 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 AIF84110.1 - 2.3 8.0 8.1 0.76 9.5 1.9 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Gar1 PF04410.9 AIF84111.1 - 3.2e-07 29.9 0.0 3.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SRP19 PF01922.12 AIF84112.1 - 4.2e-17 62.5 0.1 5.1e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 SRP19 protein VWA_2 PF13519.1 AIF84113.1 - 6.5e-27 94.7 2.7 6.5e-27 94.7 1.9 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 AIF84113.1 - 2.9e-16 59.6 0.2 5.7e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 AIF84113.1 - 2.3e-06 27.3 0.0 5.4e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 AIF84113.1 - 0.076 12.1 0.2 0.31 10.1 0.1 2.0 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein Ribosomal_S8e PF01201.17 AIF84114.1 - 5.8e-29 100.8 4.2 6.2e-29 100.8 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e zf-C3HC4_3 PF13920.1 AIF84116.1 - 0.029 14.0 3.9 0.04 13.5 2.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) gp32 PF08804.5 AIF84116.1 - 0.045 13.8 0.1 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like DUF387 PF04079.11 AIF84118.1 - 9.7e-37 125.7 0.9 1.2e-36 125.4 0.6 1.1 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) TrmB PF01978.14 AIF84118.1 - 0.00047 19.8 1.4 0.017 14.7 0.1 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AIF84118.1 - 0.00056 19.6 0.1 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_15 PF12324.3 AIF84118.1 - 0.044 13.4 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase PadR PF03551.9 AIF84118.1 - 0.076 12.7 0.4 0.72 9.6 0.1 2.3 2 1 0 2 2 2 0 Transcriptional regulator PadR-like family ScpA_ScpB PF02616.9 AIF84119.1 - 4.8e-18 65.6 0.6 3.8e-08 33.2 0.0 2.1 1 1 0 2 2 2 2 ScpA/B protein DUF2207 PF09972.4 AIF84119.1 - 0.0043 15.6 0.0 0.0052 15.4 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TarH PF02203.10 AIF84120.1 - 0.082 12.7 3.4 3.4 7.4 0.7 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue AlaDh_PNT_C PF01262.16 AIF84120.1 - 0.097 12.2 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TPR_19 PF14559.1 AIF84120.1 - 1.2 9.5 4.2 1.5 9.1 0.6 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Patatin PF01734.17 AIF84121.1 - 2.8e-11 43.7 0.0 5.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 AIF84122.1 - 3.1e-12 46.8 0.0 3.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C2H2 PF00096.21 AIF84123.1 - 0.00018 21.6 0.2 0.00018 21.6 0.1 1.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF84123.1 - 0.00032 20.8 0.8 0.00053 20.1 0.6 1.5 1 1 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 AIF84123.1 - 0.00041 20.4 0.5 0.00041 20.4 0.3 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AIF84123.1 - 0.0089 16.1 0.5 0.0094 16.0 0.4 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AIF84123.1 - 0.035 14.2 0.2 0.035 14.2 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 AIF84123.1 - 0.043 14.1 1.6 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 AIF84123.1 - 0.058 13.3 2.5 0.2 11.5 1.7 1.8 1 1 0 1 1 1 0 C2H2-type zinc finger Cytochrome_C7 PF14522.1 AIF84123.1 - 0.13 11.8 0.3 0.17 11.5 0.2 1.3 1 1 0 1 1 1 0 Cytochrome c7 zf-DBF PF07535.7 AIF84123.1 - 0.14 11.8 1.7 0.18 11.4 1.2 1.2 1 0 0 1 1 1 0 DBF zinc finger Copper-bind PF00127.15 AIF84124.1 - 8.8e-13 48.3 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF84124.1 - 5.5e-07 29.4 0.0 1.4e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Cupredoxin-like domain C1-set PF07654.10 AIF84124.1 - 0.0049 16.8 0.1 0.0081 16.1 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain HTH_45 PF14947.1 AIF84125.1 - 5.6e-18 64.5 0.4 1.1e-17 63.5 0.3 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix DUF2513 PF10711.4 AIF84125.1 - 0.028 14.4 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_24 PF13412.1 AIF84125.1 - 0.12 11.7 1.3 0.18 11.2 0.0 1.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 AIF84126.1 - 8e-17 60.8 0.0 2.6e-16 59.2 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DUF2250 PF10007.4 AIF84126.1 - 0.03 14.2 0.4 0.15 11.9 0.3 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) MEDS PF14417.1 AIF84128.1 - 7.3e-10 38.2 0.0 9.7e-10 37.8 0.0 1.2 1 1 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain KaiC PF06745.8 AIF84128.1 - 0.00026 20.1 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 KaiC HTH_45 PF14947.1 AIF84129.1 - 1.8e-15 56.4 0.3 2.9e-15 55.8 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DUF1428 PF07237.6 AIF84130.1 - 2.8e-05 23.9 0.1 4.1e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1428) Hydrolase_2 PF07486.7 AIF84130.1 - 0.096 13.2 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Cell Wall Hydrolase Methyltransf_21 PF05050.7 AIF84132.1 - 5e-27 94.8 0.0 6.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.11 AIF84132.1 - 2.1e-09 37.2 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 AIF84132.1 - 7.7e-09 36.1 0.0 1.5e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain V_cholerae_RfbT PF05575.6 AIF84132.1 - 2.7e-06 26.6 0.0 4.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_23 PF13489.1 AIF84132.1 - 2.6e-05 24.0 0.0 0.00027 20.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 AIF84132.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AIF84132.1 - 0.0022 17.9 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF84132.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 AIF84132.1 - 0.039 14.4 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HTH_24 PF13412.1 AIF84134.1 - 1e-05 24.7 0.5 2.7e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF84134.1 - 0.0021 17.5 1.2 0.0032 16.9 0.1 1.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain EPO_TPO PF00758.13 AIF84134.1 - 0.038 13.6 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin HCaRG PF07258.9 AIF84134.1 - 0.067 12.7 0.1 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 HCaRG protein PSCyt3 PF07627.6 AIF84136.1 - 0.0054 16.5 0.6 0.0074 16.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1588) zf-RING_4 PF14570.1 AIF84136.1 - 0.027 14.0 0.1 4.3 6.9 0.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 AIF84136.1 - 0.028 14.3 0.1 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger Cytochrome_C7 PF14522.1 AIF84136.1 - 0.035 13.7 0.4 0.053 13.1 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c7 zf-C3HC4 PF00097.20 AIF84136.1 - 0.037 13.6 0.5 9.5 5.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AIF84136.1 - 0.13 12.2 0.9 8.4 6.5 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RHH_1 PF01402.16 AIF84137.1 - 0.0012 18.6 0.3 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family HicB PF05534.7 AIF84137.1 - 0.045 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 HicB family Arc PF03869.9 AIF84137.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Arc-like DNA binding domain SBP_bac_3 PF00497.15 AIF84138.1 - 9.2e-56 188.5 0.1 1.1e-55 188.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 AIF84138.1 - 0.036 13.4 1.2 4.7 6.5 0.2 2.2 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 AIF84138.1 - 0.063 12.6 0.4 1.2 8.4 0.3 2.1 1 1 0 1 1 1 0 NMT1-like family HTH_Tnp_IS1 PF12759.2 AIF84143.1 - 0.11 11.8 0.1 0.51 9.8 0.0 1.9 2 0 0 2 2 2 0 InsA C-terminal domain bPH_3 PF14470.1 AIF84144.1 - 1.5e-05 25.2 0.0 1.7e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial PH domain bPH_1 PF08000.6 AIF84144.1 - 0.012 15.1 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial PH domain A2M_N PF01835.14 AIF84145.1 - 7.5 6.8 8.4 1.9 8.7 0.1 2.9 3 0 0 3 3 3 0 MG2 domain DUF4398 PF14346.1 AIF84146.1 - 3.8e-06 26.8 14.4 0.00011 22.2 5.3 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4398) MarR_2 PF12802.2 AIF84146.1 - 3.6e-05 23.3 0.0 0.00013 21.5 0.0 1.9 1 0 0 1 1 1 1 MarR family Cupredoxin_1 PF13473.1 AIF84146.1 - 0.0014 18.4 0.0 0.0055 16.5 0.0 2.1 2 0 0 2 2 2 1 Cupredoxin-like domain HTH_24 PF13412.1 AIF84146.1 - 0.0077 15.6 0.1 0.014 14.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 AIF84146.1 - 0.012 15.2 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain ATP-synt_DE PF00401.15 AIF84146.1 - 0.026 14.3 0.1 0.026 14.3 0.1 2.5 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SNAP PF14938.1 AIF84146.1 - 1.2 8.2 7.2 1.8 7.6 5.0 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Kelch_5 PF13854.1 AIF84149.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Kelch motif NnrS PF05940.7 AIF84149.1 - 4.7 6.0 44.5 1.1e+02 1.4 30.9 2.4 1 1 0 1 1 1 0 NnrS protein zf-C2H2_4 PF13894.1 AIF84150.1 - 0.0012 18.9 1.5 0.002 18.3 0.6 1.7 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 AIF84150.1 - 0.011 14.3 0.4 0.011 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-RanBP PF00641.13 AIF84150.1 - 0.035 13.2 1.0 0.065 12.3 0.7 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF2852 PF11014.3 AIF84150.1 - 0.091 12.7 0.3 0.1 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) zf-C2H2 PF00096.21 AIF84150.1 - 0.12 12.7 0.8 0.22 11.9 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type GCN5L1 PF06320.8 AIF84152.1 - 0.023 14.5 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF724 PF05266.9 AIF84152.1 - 0.037 13.6 1.3 0.059 12.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Vps51 PF08700.6 AIF84152.1 - 0.055 13.3 0.5 0.52 10.1 0.0 2.4 2 0 0 2 2 2 0 Vps51/Vps67 DASH_Dad4 PF08650.5 AIF84152.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad4 DUF4149 PF13664.1 AIF84153.1 - 0.13 12.3 2.3 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF1206 PF06724.6 AIF84153.1 - 1.6 8.5 5.8 1.1 9.0 0.6 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) UPF0104 PF03706.8 AIF84153.1 - 2.2 7.4 11.2 1.5 8.0 2.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) SCO1-SenC PF02630.9 AIF84154.1 - 0.015 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 SCO1/SenC HemX PF04375.9 AIF84154.1 - 0.024 13.2 0.0 0.041 12.4 0.0 1.4 1 0 0 1 1 1 0 HemX RFC1 PF08519.7 AIF84154.1 - 0.084 12.6 0.3 0.66 9.7 0.1 2.1 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain DcuC PF03606.10 AIF84154.1 - 0.097 10.8 0.1 0.13 10.4 0.1 1.4 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF998 PF06197.8 AIF84155.1 - 0.032 13.5 3.3 0.053 12.8 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF998) NMN_transporter PF04973.7 AIF84155.1 - 0.053 12.9 2.9 0.058 12.8 1.5 1.4 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter hDGE_amylase PF14701.1 AIF84159.1 - 0.04 12.8 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Abi_C PF14355.1 AIF84159.1 - 0.097 12.6 0.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Abortive infection C-terminus CppA_N PF14506.1 AIF84164.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 CppA N-terminal Ribosomal_L37ae PF01780.14 AIF84164.1 - 0.077 12.8 0.0 6.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF2397 PF09660.5 AIF84164.1 - 0.081 11.5 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF1936 PF09151.5 AIF84165.1 - 0.023 14.1 0.1 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) PCP_red PF08369.5 AIF84166.1 - 0.039 13.8 2.4 0.12 12.2 0.1 2.9 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit HrpF PF06266.7 AIF84166.1 - 9.8 6.3 11.0 7.8 6.7 0.3 3.6 3 0 0 3 3 3 0 HrpF protein zf-met PF12874.2 AIF84170.1 - 0.013 15.7 0.2 0.034 14.3 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Mut7-C PF01927.11 AIF84170.1 - 0.021 14.7 2.0 0.05 13.5 1.4 1.8 1 1 0 1 1 1 0 Mut7-C RNAse domain zf-C2H2_4 PF13894.1 AIF84170.1 - 2.6 8.5 5.4 6.4 7.3 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger NinF PF05810.7 AIF84171.1 - 0.014 15.1 0.2 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 NinF protein Tricho_coat PF05892.6 AIF84171.1 - 0.063 12.4 0.5 0.28 10.3 0.1 1.9 2 0 0 2 2 2 0 Trichovirus coat protein Transpos_assoc PF13963.1 AIF84171.1 - 0.12 12.3 0.6 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 Transposase-associated domain ArsC PF03960.10 AIF84172.1 - 0.042 13.9 0.1 33 4.6 0.0 3.3 2 1 1 3 3 3 0 ArsC family CLAMP PF14769.1 AIF84172.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 DUF385 PF04075.9 AIF84173.1 - 8.8e-09 35.4 0.0 9.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF385) DUF2255 PF10012.4 AIF84173.1 - 4.8e-08 32.9 0.0 5.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) DUF423 PF04241.10 AIF84174.1 - 0.093 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Bmp PF02608.9 AIF84177.1 - 3.5e-57 193.4 2.3 3.8e-57 193.3 1.6 1.0 1 0 0 1 1 1 1 Basic membrane protein Peripla_BP_4 PF13407.1 AIF84177.1 - 4.3e-05 22.9 4.8 5.5e-05 22.6 3.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein domain Fe-ADH PF00465.14 AIF84177.1 - 0.0099 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase HATPase_c PF02518.21 AIF84178.1 - 6.3e-27 93.4 0.1 1.3e-26 92.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF84178.1 - 4.5e-11 42.5 0.2 1.9e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AIF84178.1 - 0.00017 21.2 0.0 0.0005 19.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 AIF84178.1 - 0.011 15.3 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 GHKL domain Response_reg PF00072.19 AIF84179.1 - 1.7e-18 66.6 0.0 1.9e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HicB PF05534.7 AIF84180.1 - 0.023 14.2 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 HicB family DUF970 PF06153.6 AIF84180.1 - 0.046 13.6 0.7 0.25 11.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF970) RHH_4 PF13467.1 AIF84180.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain tRNA_anti-codon PF01336.20 AIF84181.1 - 9.9e-09 34.9 0.2 1.2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4397 PF14344.1 AIF84181.1 - 0.093 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) PAC2 PF09754.4 AIF84182.1 - 1.9e-44 152.1 0.0 2.2e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 PAC2 family GST_C_2 PF13410.1 AIF84183.1 - 0.0028 17.5 0.5 0.067 13.0 0.0 2.8 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AIF84183.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain 7tm_2 PF00002.19 AIF84184.1 - 0.1 11.6 1.5 0.19 10.7 1.0 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF1228 PF06779.9 AIF84184.1 - 1.6 8.7 9.6 0.21 11.6 2.0 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1228) SNF5 PF04855.7 AIF84186.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 DUF1059 PF06348.6 AIF84188.1 - 7.2e-20 70.5 1.0 7.9e-20 70.4 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) KGG PF10685.4 AIF84190.1 - 0.062 13.2 0.5 0.062 13.2 0.3 2.8 4 0 0 4 4 4 0 Stress-induced bacterial acidophilic repeat motif N36 PF11438.3 AIF84190.1 - 6.6 6.3 7.3 1.4 8.4 0.6 2.2 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) PvlArgDC PF01862.11 AIF84191.1 - 1.8e-62 209.8 0.0 2e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) IF3_N PF05198.11 AIF84191.1 - 0.011 15.5 0.2 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain zf-C2H2_6 PF13912.1 AIF84192.1 - 0.00018 21.3 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AIF84192.1 - 0.0002 21.4 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF84192.1 - 0.0011 19.1 0.1 0.0015 18.7 0.1 1.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 AIF84192.1 - 0.004 17.2 0.1 0.004 17.2 0.0 1.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) RAP1 PF07218.6 AIF84192.1 - 0.037 12.1 0.0 0.038 12.1 0.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2_3 PF13878.1 AIF84192.1 - 0.038 13.5 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_jaz PF12171.3 AIF84192.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding RecR PF02132.10 AIF84192.1 - 0.068 12.6 0.1 0.13 11.7 0.0 1.5 1 1 1 2 2 2 0 RecR protein GcpE PF04551.9 AIF84192.1 - 0.11 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 GcpE protein zf-H2C2_2 PF13465.1 AIF84192.1 - 1.1 9.6 2.9 20 5.7 0.1 2.5 2 1 0 2 2 2 0 Zinc-finger double domain WYL PF13280.1 AIF84193.1 - 0.00061 19.6 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 WYL domain Epimerase_2 PF02350.14 AIF84197.1 - 3.7e-96 321.9 0.0 4.3e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.7 AIF84197.1 - 2.4e-05 23.4 0.0 3.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Methyltransf_23 PF13489.1 AIF84198.1 - 4.1e-16 59.1 0.0 7.2e-16 58.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84198.1 - 1e-12 47.8 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84198.1 - 5.7e-10 39.4 0.0 9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF84198.1 - 1.3e-09 38.4 0.0 3.1e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84198.1 - 1.3e-09 38.3 0.0 2.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84198.1 - 3e-08 34.2 0.0 5.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 AIF84198.1 - 3.4e-06 26.5 0.0 4.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 AIF84198.1 - 5.4e-06 25.8 0.0 4.3e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain NodS PF05401.6 AIF84198.1 - 9.3e-06 25.1 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 AIF84198.1 - 2.1e-05 23.6 0.0 4.5e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 AIF84198.1 - 0.00038 19.6 0.1 0.00073 18.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AIF84198.1 - 0.0006 19.8 0.0 0.012 15.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 AIF84198.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bin3 PF06859.7 AIF84198.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Glyco_trans_4_4 PF13579.1 AIF84199.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 AIF84199.1 - 0.061 13.1 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glyco_trans_1_4 PF13692.1 AIF84200.1 - 2.1e-10 40.8 0.0 4.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AIF84200.1 - 9e-09 35.6 0.0 2.9e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 AIF84200.1 - 1e-06 28.6 0.4 2.6e-06 27.2 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 AIF84200.1 - 0.00013 22.2 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 AIF84200.1 - 0.0036 17.1 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Synapsin PF02078.11 AIF84200.1 - 0.01 15.9 0.1 0.04 14.0 0.0 1.9 1 1 1 2 2 2 0 Synapsin, N-terminal domain PIG-L PF02585.12 AIF84200.1 - 0.026 15.0 0.0 0.071 13.6 0.0 1.7 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase HxlR PF01638.12 AIF84201.1 - 2.9e-22 78.1 0.8 3.4e-22 77.8 0.6 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.17 AIF84201.1 - 0.063 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 MarR family DUF651 PF04895.7 AIF84201.1 - 0.27 10.8 1.2 1.2 8.8 0.0 2.1 1 1 0 2 2 2 0 Archaeal protein of unknown function (DUF651) SHOCT PF09851.4 AIF84202.1 - 6.2e-08 31.8 0.0 7.9e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Short C-terminal domain Polyketide_cyc2 PF10604.4 AIF84204.1 - 1.9e-15 57.2 0.1 2.1e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF84204.1 - 1.3e-07 31.6 0.0 2.8e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 AIF84204.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) DUF1857 PF08982.6 AIF84204.1 - 0.033 13.7 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) HTH_45 PF14947.1 AIF84206.1 - 7.4e-07 28.8 1.3 8.9e-07 28.6 0.9 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 AIF84206.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 MarR family DUF2680 PF10925.3 AIF84206.1 - 0.051 13.4 0.1 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF4013 PF13197.1 AIF84207.1 - 0.0019 17.5 1.9 0.0024 17.2 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) Sdh_cyt PF01127.17 AIF84207.1 - 0.011 15.6 1.8 0.016 15.0 1.3 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CemA PF03040.9 AIF84207.1 - 0.016 14.8 1.7 1 8.9 0.0 2.1 2 0 0 2 2 2 0 CemA family DUF4231 PF14015.1 AIF84207.1 - 0.2 11.6 1.8 0.41 10.6 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3139 PF11337.3 AIF84207.1 - 0.25 11.6 7.3 9.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) SP_C-Propep PF08999.5 AIF84207.1 - 0.29 10.6 2.6 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF843 PF05814.6 AIF84207.1 - 0.53 10.1 5.5 1 9.2 0.1 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) MpPF26 PF07666.6 AIF84207.1 - 1.5 8.7 10.1 2.6 7.9 3.9 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 HATPase_c PF02518.21 AIF84209.1 - 1.8e-28 98.4 0.0 4.4e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF84209.1 - 1.6e-14 53.6 1.0 3.7e-14 52.4 0.7 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 AIF84209.1 - 0.00016 21.4 0.0 0.00095 18.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.1 AIF84209.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AIF84209.1 - 0.061 12.9 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FliJ PF02050.11 AIF84209.1 - 0.13 12.3 5.9 0.17 11.9 1.0 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein FliD_N PF02465.13 AIF84209.1 - 3 8.2 6.3 4.1 7.8 1.1 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus zf-AN1 PF01428.11 AIF84210.1 - 0.12 12.2 9.7 0.21 11.4 6.7 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger zf-HIT PF04438.11 AIF84210.1 - 0.38 10.4 4.4 0.63 9.7 3.0 1.4 1 0 0 1 1 1 0 HIT zinc finger LysM PF01476.15 AIF84211.1 - 0.035 13.9 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 LysM domain Formyl_trans_N PF00551.14 AIF84213.1 - 4.1e-45 153.5 0.0 5.7e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.1 AIF84213.1 - 9.6e-11 41.2 0.0 1.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 AIF84213.1 - 9.6e-07 28.1 0.1 3.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.1 AIF84213.1 - 2.8e-06 27.5 0.3 2.8e-05 24.3 0.1 2.5 3 0 0 3 3 3 1 ACT domain Creatininase PF02633.9 AIF84214.1 - 5.9e-66 221.9 1.0 7.3e-66 221.6 0.7 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase LSM PF01423.17 AIF84215.1 - 4.4e-22 77.3 1.6 5.1e-22 77.2 1.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AIF84215.1 - 0.017 15.0 0.1 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_L37e PF01907.14 AIF84216.1 - 1.6e-22 79.0 12.5 1.9e-22 78.8 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.14 AIF84216.1 - 0.00094 18.8 0.8 0.001 18.7 0.6 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 AIF84216.1 - 0.0022 17.7 1.6 0.0027 17.4 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon DNA_RNApol_7kD PF03604.8 AIF84216.1 - 0.0022 17.4 8.3 0.0043 16.4 1.2 2.2 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit Stc1 PF12898.2 AIF84216.1 - 0.0054 16.7 1.7 0.0055 16.7 1.2 1.1 1 0 0 1 1 1 1 Stc1 domain Ribosomal_S14 PF00253.16 AIF84216.1 - 0.0063 15.8 1.4 0.0063 15.8 0.9 2.1 1 1 1 2 2 2 1 Ribosomal protein S14p/S29e Zn-ribbon_8 PF09723.5 AIF84216.1 - 0.009 15.9 0.8 3.1 7.8 0.1 2.1 2 0 0 2 2 2 2 Zinc ribbon domain GCC2_GCC3 PF07699.8 AIF84216.1 - 0.012 15.1 3.0 0.019 14.5 2.1 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 zinc_ribbon_6 PF14599.1 AIF84216.1 - 0.015 15.0 1.6 0.018 14.8 1.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon zf-ribbon_3 PF13248.1 AIF84216.1 - 0.019 14.1 3.7 0.04 13.1 2.6 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.3 AIF84216.1 - 0.036 13.9 3.5 0.048 13.5 2.5 1.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) OrfB_Zn_ribbon PF07282.6 AIF84216.1 - 0.041 13.5 3.9 0.051 13.2 2.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.6 AIF84216.1 - 0.055 12.9 5.7 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.6 AIF84216.1 - 0.06 13.1 3.9 0.12 12.2 2.7 1.5 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 AIF84216.1 - 0.075 12.5 6.7 0.13 11.8 4.5 1.5 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 AIF84216.1 - 0.075 12.5 2.9 0.078 12.4 2.0 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain LIM PF00412.17 AIF84216.1 - 0.09 12.8 5.4 0.24 11.4 3.7 1.8 1 1 0 1 1 1 0 LIM domain DnaJ_CXXCXGXG PF00684.14 AIF84216.1 - 0.16 11.9 4.6 0.22 11.6 3.2 1.1 1 0 0 1 1 1 0 DnaJ central domain Baculo_ME53 PF06061.6 AIF84216.1 - 0.24 10.3 3.1 0.25 10.3 2.2 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 DUF2082 PF09855.4 AIF84216.1 - 0.27 11.0 3.8 3.2 7.6 0.2 2.2 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) NRDD PF13597.1 AIF84216.1 - 0.38 8.7 2.2 0.36 8.8 1.6 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase GFA PF04828.9 AIF84216.1 - 0.4 10.6 4.5 1.5 8.8 3.1 1.8 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_4 PF13717.1 AIF84216.1 - 0.55 9.9 7.8 1.5 8.6 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 AIF84216.1 - 0.59 9.8 6.0 7.1 6.3 0.5 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 AIF84216.1 - 0.86 9.2 8.0 1.8 8.1 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 AIF84216.1 - 0.98 9.1 8.8 4.1 7.1 1.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-Mss51 PF13824.1 AIF84216.1 - 1.1 9.1 5.2 1.8 8.4 0.3 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 YhfH PF14149.1 AIF84216.1 - 3.6 7.4 8.2 7 6.5 0.4 2.2 1 1 1 2 2 2 0 YhfH-like protein RNA_POL_M_15KD PF02150.11 AIF84216.1 - 3.7 7.3 7.3 4.4 7.0 0.8 2.1 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.1 AIF84216.1 - 4.9 7.4 12.1 75 3.6 8.4 2.2 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain YlqD PF11068.3 AIF84217.1 - 0.2 11.7 6.5 2.1 8.3 2.8 2.2 2 0 0 2 2 2 0 YlqD protein OSTbeta PF15048.1 AIF84217.1 - 1.5 8.9 5.7 0.53 10.3 0.2 2.5 2 1 1 3 3 3 0 Organic solute transporter subunit beta protein HAUS-augmin3 PF14932.1 AIF84217.1 - 1.5 7.9 10.4 0.05 12.7 0.5 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Uds1 PF15456.1 AIF84217.1 - 1.8 8.5 12.4 0.21 11.5 1.8 2.6 1 1 0 2 2 2 0 Up-regulated During Septation CM_2 PF01817.16 AIF84217.1 - 3.1 7.9 10.0 9.4 6.4 0.4 3.2 2 1 1 3 3 3 0 Chorismate mutase type II Phasin PF05597.6 AIF84217.1 - 3.6 7.3 10.5 0.42 10.3 0.7 3.0 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) VIT1 PF01988.14 AIF84217.1 - 9.5 5.6 8.6 1.2 8.6 2.8 1.9 1 1 0 2 2 2 0 VIT family Asn_synthase PF00733.16 AIF84218.1 - 1.1e-23 84.0 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AIF84218.1 - 0.0022 16.9 0.0 0.0036 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 AIF84218.1 - 0.013 14.0 0.0 0.024 13.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.8 AIF84218.1 - 0.052 12.8 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 AIF84218.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Glycos_transf_2 PF00535.21 AIF84219.1 - 6.1e-20 71.5 0.3 9.9e-20 70.8 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIF84219.1 - 1e-09 38.5 0.2 6.7e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AIF84219.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.1 AIF84219.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family DUF633 PF04816.7 AIF84220.1 - 0.021 14.1 0.2 0.027 13.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF633) THF_DHG_CYH_C PF02882.14 AIF84221.1 - 7.8e-65 216.8 0.6 1.1e-64 216.3 0.4 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AIF84221.1 - 6.7e-43 145.4 0.4 1.2e-42 144.5 0.3 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 AIF84221.1 - 0.00069 19.7 0.1 0.0028 17.7 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 AIF84221.1 - 0.006 16.8 0.2 0.021 15.0 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF2639 PF11121.3 AIF84221.1 - 0.046 13.2 0.1 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) 5-FTHF_cyc-lig PF01812.15 AIF84222.1 - 3.2e-34 118.3 0.0 3.6e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GARS_A PF01071.14 AIF84223.1 - 2.7e-78 262.0 0.5 3.7e-78 261.5 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 AIF84223.1 - 8.4e-31 106.4 0.1 2.3e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 AIF84223.1 - 3.1e-26 91.3 0.4 7.7e-26 90.0 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 AIF84223.1 - 2.5e-15 56.6 0.1 9.7e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIF84223.1 - 6.1e-08 31.7 0.2 6.2e-06 25.1 0.1 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AIF84223.1 - 2.9e-07 30.4 0.0 5.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AIF84223.1 - 4.8e-05 22.7 0.0 0.00013 21.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AIF84223.1 - 0.00042 19.7 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 AIF84223.1 - 0.00075 18.8 0.4 0.0044 16.3 0.2 2.0 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 AIF84223.1 - 0.00087 18.8 0.0 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 AIF84223.1 - 0.0036 16.6 0.2 0.011 15.1 0.2 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.1 AIF84223.1 - 0.051 12.6 0.1 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp SWIM PF04434.12 AIF84224.1 - 0.00036 19.9 0.2 0.00057 19.2 0.1 1.3 1 0 0 1 1 1 1 SWIM zinc finger FliW PF02623.10 AIF84224.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.7 1 1 0 1 1 1 0 FliW protein Metallophos PF00149.23 AIF84225.1 - 1.8e-08 34.0 0.1 1.4e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AIF84225.1 - 6e-08 32.6 0.0 1.2e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CPSase_L_D2 PF02786.12 AIF84226.1 - 8.7e-107 355.1 0.0 5.4e-74 248.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 AIF84226.1 - 4.8e-43 145.8 0.1 9.6e-43 144.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AIF84226.1 - 1.2e-30 106.6 0.1 2.4e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 AIF84226.1 - 1.2e-23 83.3 0.3 2.1e-17 63.2 0.0 3.5 4 0 0 4 4 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 AIF84226.1 - 1e-22 80.3 0.1 1.7e-14 53.3 0.0 3.7 2 2 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 AIF84226.1 - 8.1e-14 51.3 0.2 4.5e-13 48.9 0.0 2.4 3 0 0 3 3 3 1 MGS-like domain ATP-grasp PF02222.17 AIF84226.1 - 2.8e-13 49.5 0.3 4.4e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AIF84226.1 - 2.6e-11 43.3 0.2 2.5e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 AIF84226.1 - 8.7e-08 31.8 0.1 0.00016 21.2 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 AIF84226.1 - 1.4e-05 24.7 0.2 0.00047 19.7 0.0 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 AIF84226.1 - 0.00015 21.6 0.1 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 AIF84226.1 - 0.0019 17.4 0.0 1.2 8.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peripla_BP_6 PF13458.1 AIF84226.1 - 0.097 12.0 0.0 1.2 8.3 0.0 2.5 2 1 1 3 3 3 0 Periplasmic binding protein CPSase_sm_chain PF00988.17 AIF84227.1 - 5.9e-49 164.9 0.0 9.4e-49 164.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AIF84227.1 - 1.3e-42 145.4 0.0 2.6e-42 144.4 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIF84227.1 - 1.3e-09 37.7 0.1 5.6e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Peptidase C26 DUF2254 PF10011.4 AIF84228.1 - 0.07 11.5 0.7 0.081 11.3 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Iso_dh PF00180.15 AIF84229.1 - 2.1e-98 329.4 0.3 2.4e-98 329.2 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 AIF84229.1 - 0.0046 16.2 0.0 0.0092 15.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA HMGL-like PF00682.14 AIF84230.1 - 2.5e-80 269.5 2.8 4.7e-80 268.6 1.9 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 AIF84230.1 - 5.7e-31 107.0 2.6 1.3e-30 105.9 1.8 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain ALS_ss_C PF10369.4 AIF84231.1 - 8.9e-31 105.4 1.1 3.1e-28 97.2 0.0 2.8 2 1 0 2 2 2 2 Small subunit of acetolactate synthase ACT_5 PF13710.1 AIF84231.1 - 1.9e-20 72.4 0.9 6.6e-20 70.6 0.3 1.9 2 0 0 2 2 2 1 ACT domain ACT PF01842.20 AIF84231.1 - 5.6e-17 60.8 0.1 1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 AIF84231.1 - 5.8e-07 29.7 0.6 1.1e-06 28.8 0.5 1.4 1 0 0 1 1 1 1 ACT domain NIL PF09383.5 AIF84231.1 - 0.0013 18.2 0.2 0.45 10.1 0.0 2.3 2 0 0 2 2 2 2 NIL domain Saccharop_dh_N PF04455.7 AIF84231.1 - 0.0073 16.4 0.3 0.018 15.1 0.2 1.6 1 1 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region ACT_6 PF13740.1 AIF84231.1 - 0.043 13.5 0.1 0.96 9.2 0.1 2.3 2 0 0 2 2 2 0 ACT domain ZipA_C PF04354.8 AIF84231.1 - 0.047 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain Acylphosphatase PF00708.13 AIF84231.1 - 0.048 13.7 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Acylphosphatase Trans_reg_C PF00486.23 AIF84231.1 - 0.083 12.8 0.2 0.44 10.4 0.1 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal TPP_enzyme_N PF02776.13 AIF84232.1 - 8e-63 210.9 0.5 1.1e-61 207.2 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AIF84232.1 - 7.8e-46 155.2 0.1 2.5e-45 153.5 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AIF84232.1 - 4.8e-45 152.8 0.5 7.8e-44 148.9 0.2 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SnoaL_3 PF13474.1 AIF84233.1 - 2.3e-10 40.5 0.0 2.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AIF84233.1 - 0.0001 22.4 0.0 0.00013 22.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3804 PF12707.2 AIF84233.1 - 0.0037 16.8 0.3 0.0063 16.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3804) SnoaL_4 PF13577.1 AIF84233.1 - 0.0037 17.1 0.0 0.0052 16.6 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 AIF84233.1 - 0.011 16.2 0.2 0.017 15.6 0.2 1.5 1 1 0 1 1 1 0 Putative lumazine-binding CaMKII_AD PF08332.5 AIF84233.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association DeoC PF01791.4 AIF84234.1 - 1.3e-19 70.4 0.3 1.7e-18 66.8 0.0 2.0 1 1 1 2 2 2 2 DeoC/LacD family aldolase ADH_N PF08240.7 AIF84235.1 - 1.4e-24 85.9 1.6 2.5e-24 85.1 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIF84235.1 - 1.8e-22 79.2 0.0 3.6e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 AIF84235.1 - 0.057 11.8 0.1 0.094 11.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein F5_F8_type_C PF00754.20 AIF84236.1 - 4.5e-15 55.6 3.2 4.5e-15 55.6 2.2 2.5 3 0 0 3 3 3 1 F5/8 type C domain Big_3_4 PF13754.1 AIF84236.1 - 8e-05 22.8 1.3 8e-05 22.8 0.9 3.6 5 0 0 5 5 5 1 Bacterial Ig-like domain (group 3) HYR PF02494.11 AIF84236.1 - 0.0065 16.4 0.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 1 HYR domain Mo-co_dimer PF03404.11 AIF84236.1 - 0.034 13.7 1.0 0.19 11.3 0.2 2.6 1 1 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain Tyr-DNA_phospho PF06087.7 AIF84236.1 - 0.061 11.9 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Sad1_UNC PF07738.8 AIF84236.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal zf-C2H2_4 PF13894.1 AIF84238.1 - 0.00045 20.3 0.1 0.00076 19.6 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF84238.1 - 0.00068 19.8 0.3 0.0013 18.9 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 AIF84238.1 - 0.014 15.4 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 AIF84238.1 - 0.016 15.0 0.2 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AIF84238.1 - 0.028 14.5 0.2 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.1 AIF84238.1 - 0.04 13.5 0.3 0.071 12.8 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF84238.1 - 0.042 13.4 0.3 0.069 12.7 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Desulfoferrod_N PF06397.7 AIF84238.1 - 0.065 12.6 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-H2C2_2 PF13465.1 AIF84238.1 - 0.079 13.2 2.9 0.14 12.4 2.0 1.5 1 0 0 1 1 1 0 Zinc-finger double domain T4_baseplate PF12322.3 AIF84238.1 - 0.11 11.7 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-Di19 PF05605.7 AIF84238.1 - 0.11 12.5 0.3 0.14 12.2 0.2 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding KAP PF05804.7 AIF84239.1 - 0.018 12.9 0.0 0.018 12.9 0.0 1.0 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) A1_Propeptide PF07966.7 AIF84239.1 - 0.042 13.6 0.2 0.093 12.5 0.0 1.7 2 0 0 2 2 2 0 A1 Propeptide DUF3944 PF13099.1 AIF84239.1 - 0.072 12.5 1.9 0.22 11.0 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3944) HTH_3 PF01381.17 AIF84240.1 - 1.1e-05 25.1 0.2 3.4e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_37 PF13744.1 AIF84240.1 - 0.00017 21.3 0.0 0.00036 20.2 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 AIF84240.1 - 0.00031 20.7 0.1 0.0021 18.0 0.1 2.1 1 1 0 1 1 1 1 Helix-turn-helix domain CPSase_L_D3 PF02787.14 AIF84240.1 - 0.009 15.7 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_26 PF13443.1 AIF84240.1 - 0.015 15.4 0.1 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain P22_Cro PF14549.1 AIF84240.1 - 0.021 14.5 0.2 0.097 12.4 0.0 2.1 2 1 1 3 3 3 0 DNA-binding transcriptional regulator Cro Sigma70_r4_2 PF08281.7 AIF84240.1 - 0.038 13.4 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 MarR_2 PF12802.2 AIF84240.1 - 0.038 13.6 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 MarR family DUF2666 PF10869.3 AIF84240.1 - 0.043 13.8 0.1 0.071 13.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2666) HTH_23 PF13384.1 AIF84240.1 - 0.076 12.6 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Zn-ribbon_8 PF09723.5 AIF84240.1 - 0.17 11.8 0.4 0.77 9.7 0.2 1.9 2 0 0 2 2 2 0 Zinc ribbon domain IncA PF04156.9 AIF84241.1 - 1.6e-05 24.5 0.1 2.1e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 IncA protein DUF1469 PF07332.6 AIF84241.1 - 5.9e-05 22.7 1.8 7.4e-05 22.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) TctB PF07331.6 AIF84241.1 - 0.00016 21.3 0.2 0.00017 21.2 0.1 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF998 PF06197.8 AIF84241.1 - 0.00031 20.0 1.5 0.00034 19.9 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF998) UPF0104 PF03706.8 AIF84241.1 - 0.0012 18.2 0.1 0.0012 18.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF2371 PF10177.4 AIF84241.1 - 0.0016 18.3 0.4 0.0026 17.6 0.1 1.5 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2371) NfeD PF01957.13 AIF84241.1 - 0.0031 17.6 0.5 0.0036 17.4 0.4 1.0 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding DsbD_2 PF13386.1 AIF84241.1 - 0.015 15.0 0.1 0.016 14.9 0.1 1.0 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF308 PF03729.8 AIF84241.1 - 0.018 15.0 2.1 0.023 14.6 1.5 1.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) DUF3185 PF11381.3 AIF84241.1 - 0.023 14.4 1.3 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Sulfate_transp PF00916.15 AIF84241.1 - 0.026 13.5 0.0 0.03 13.3 0.0 1.0 1 0 0 1 1 1 0 Sulfate transporter family TMEM219 PF14940.1 AIF84241.1 - 0.058 12.4 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane 219 OSTbeta PF15048.1 AIF84241.1 - 0.067 13.2 0.0 0.067 13.2 0.0 1.0 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2207 PF09972.4 AIF84241.1 - 0.12 10.9 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF872 PF05915.7 AIF84241.1 - 0.24 11.2 2.2 0.43 10.4 0.1 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SdpI PF13630.1 AIF84241.1 - 0.31 10.7 2.3 0.43 10.3 1.6 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF202 PF02656.10 AIF84241.1 - 0.32 11.2 5.6 0.53 10.5 3.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2905 PF11146.3 AIF84241.1 - 0.39 10.6 2.2 9.9 6.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) SPW PF03779.9 AIF84241.1 - 1.6 8.1 10.3 4.6 6.6 1.6 2.3 1 1 1 2 2 2 0 SPW repeat DUF3188 PF11384.3 AIF84241.1 - 2.4 7.7 5.4 9.8 5.8 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3188) VPEP PF07589.6 AIF84241.1 - 4.1 7.4 10.3 0.48 10.3 0.7 2.3 2 0 0 2 2 2 0 PEP-CTERM motif HTH_20 PF12840.2 AIF84242.1 - 4.3e-09 36.0 0.0 8.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_45 PF14947.1 AIF84242.1 - 2.9e-06 26.9 0.1 8.2e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.1 AIF84242.1 - 5.3e-06 25.7 0.8 1.2e-05 24.6 0.5 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AIF84242.1 - 5.5e-06 25.9 0.1 1.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 AIF84242.1 - 0.00028 21.1 0.1 0.00076 19.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain DUF4423 PF14394.1 AIF84242.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) TrmB PF01978.14 AIF84242.1 - 0.0018 17.9 0.0 0.0095 15.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AIF84242.1 - 0.0023 17.5 0.1 0.0062 16.1 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 AIF84242.1 - 0.0029 17.4 0.2 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) MarR PF01047.17 AIF84242.1 - 0.0041 16.7 0.5 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.7 AIF84242.1 - 0.0045 16.6 0.1 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 HTH domain Mrr_N PF14338.1 AIF84242.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.8 1 0 0 1 1 1 0 Mrr N-terminal domain HTH_34 PF13601.1 AIF84242.1 - 0.03 14.3 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Fe_dep_repress PF01325.14 AIF84242.1 - 0.036 14.0 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain GCFC PF07842.7 AIF84242.1 - 0.061 12.6 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein Regulator_TrmB PF11495.3 AIF84242.1 - 0.078 11.9 0.0 0.13 11.1 0.0 1.4 1 1 0 1 1 1 0 Archaeal transcriptional regulator TrmB XRCC4 PF06632.7 AIF84242.1 - 0.099 11.4 0.3 0.37 9.5 0.1 1.8 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 HTH_IclR PF09339.5 AIF84242.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain RibD_C PF01872.12 AIF84243.1 - 5.1e-24 84.9 0.0 5.9e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.14 AIF84243.1 - 4.5e-05 23.0 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase DUF1801 PF08818.6 AIF84244.1 - 4.8e-25 87.6 0.0 5.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) zf-C2H2_4 PF13894.1 AIF84245.1 - 0.0034 17.6 0.0 0.0062 16.7 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF84245.1 - 0.046 14.0 0.1 0.082 13.2 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pyr_redox_2 PF07992.9 AIF84246.1 - 7.8e-35 120.5 2.4 8.6e-34 117.1 1.7 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AIF84246.1 - 9e-26 90.0 0.1 2.2e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AIF84246.1 - 2.2e-14 53.6 0.8 2.1e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIF84246.1 - 2.6e-08 34.1 0.0 1.6e-05 25.0 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AIF84246.1 - 2e-06 27.0 0.0 7.5e-05 21.7 0.0 2.4 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 AIF84246.1 - 0.00047 19.1 3.0 0.0033 16.3 0.7 2.6 2 1 1 3 3 3 1 FAD binding domain 3HCDH_N PF02737.13 AIF84246.1 - 0.0032 17.1 0.2 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 AIF84246.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 AIF84246.1 - 0.077 11.8 1.2 0.33 9.8 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 AIF84246.1 - 0.16 10.4 0.6 0.41 9.0 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein RNA_pol_Rpb6 PF01192.17 AIF84247.1 - 1.3e-12 47.2 0.0 3e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 Cyclophil_like PF04126.8 AIF84248.1 - 1.3e-09 37.7 0.0 1.9e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin-like DUF3830 PF12903.2 AIF84248.1 - 0.044 13.1 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) ACP_syn_III PF08545.5 AIF84248.1 - 0.09 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pro_isomerase PF00160.16 AIF84248.1 - 0.12 12.5 0.1 0.64 10.2 0.1 1.9 1 1 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S25 PF03297.10 AIF84249.1 - 1.8e-06 27.8 3.5 2.3e-06 27.5 2.4 1.2 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.14 AIF84249.1 - 0.0028 17.3 0.2 0.0042 16.7 0.2 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AIF84249.1 - 0.01 15.2 0.1 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 AIF84249.1 - 0.013 15.1 0.1 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 MarR family DUF4355 PF14265.1 AIF84249.1 - 0.018 14.9 1.3 0.021 14.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) MarR_2 PF12802.2 AIF84249.1 - 0.023 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 AIF84249.1 - 0.043 13.9 0.4 0.061 13.4 0.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.1 AIF84249.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.5 AIF84249.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain DNA_ligase_A_M PF01068.16 AIF84250.1 - 9.8e-53 178.5 0.4 2.4e-52 177.2 0.2 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AIF84250.1 - 8.8e-48 162.4 0.2 2e-47 161.2 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AIF84250.1 - 9.3e-21 74.0 0.0 2.1e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region 2-Hacid_dh_C PF02826.14 AIF84253.1 - 1.5e-46 157.7 0.0 1.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AIF84253.1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 AIF84254.1 - 2.2e-13 49.8 0.0 2.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain TFIIE-A_C-term PF11521.3 AIF84255.1 - 6.6 6.7 12.8 6.6 6.7 8.9 1.0 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha NAD_binding_1 PF00175.16 AIF84256.1 - 1.3e-22 80.3 0.0 3.1e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Rieske PF00355.21 AIF84256.1 - 1.7e-12 46.7 0.0 3.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_6 PF00970.19 AIF84256.1 - 4.5e-08 33.1 0.0 7.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Rieske_2 PF13806.1 AIF84256.1 - 1.1e-05 25.0 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_6 PF08030.7 AIF84256.1 - 0.0003 20.7 0.0 0.05 13.5 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Glyco_hydro_4 PF02056.11 AIF84256.1 - 0.096 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Ferritin PF00210.19 AIF84257.1 - 2.4e-21 75.9 1.0 3.4e-21 75.4 0.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AIF84257.1 - 0.00095 19.5 2.6 0.0035 17.6 1.8 1.8 1 1 0 1 1 1 1 Rubrerythrin PAC2 PF09754.4 AIF84259.1 - 4.3e-22 79.0 0.0 5.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Hydrolase PF00702.21 AIF84261.1 - 2e-54 185.2 4.1 4.3e-54 184.1 2.9 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AIF84261.1 - 6.3e-54 182.4 2.9 1.2e-53 181.4 2.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 AIF84261.1 - 1.2e-25 89.3 0.7 3e-15 56.1 0.3 3.4 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 AIF84261.1 - 1.6e-16 61.0 0.0 5.6e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AIF84261.1 - 5.7e-05 22.9 0.0 0.0044 16.8 0.0 3.2 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AIF84261.1 - 0.00021 20.9 4.1 0.057 12.9 1.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase PCP_red PF08369.5 AIF84261.1 - 0.0064 16.3 0.2 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit Arginase PF00491.16 AIF84264.1 - 2.9e-62 210.4 0.4 3.3e-62 210.2 0.3 1.0 1 0 0 1 1 1 1 Arginase family ECH PF00378.15 AIF84265.1 - 2e-69 233.4 3.0 2.3e-69 233.2 2.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AIF84265.1 - 0.0022 18.1 0.1 0.004 17.2 0.1 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 AIF84265.1 - 0.0049 16.6 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 GHMP_kinases_N PF00288.21 AIF84266.1 - 2.5e-16 59.4 1.6 7.7e-16 57.9 1.1 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AIF84266.1 - 2.2e-08 34.1 0.0 4.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal FlpD PF02662.11 AIF84266.1 - 0.037 13.7 0.1 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit ATP_bind_1 PF03029.12 AIF84267.1 - 6.9e-53 179.6 0.0 7.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 AIF84267.1 - 9.1e-05 22.5 0.0 0.00091 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AIF84267.1 - 0.0011 19.0 0.0 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 AIF84267.1 - 0.0026 17.7 0.0 0.0095 15.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 AIF84267.1 - 0.0031 16.9 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain DUF2075 PF09848.4 AIF84267.1 - 0.0064 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 AIF84267.1 - 0.0072 15.1 0.1 0.035 12.8 0.0 1.9 2 0 0 2 2 2 1 ArgK protein cobW PF02492.14 AIF84267.1 - 0.0076 15.7 0.4 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 AIF84267.1 - 0.0085 15.5 0.1 0.019 14.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 AIF84267.1 - 0.011 15.9 0.1 0.031 14.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AIF84267.1 - 0.02 15.7 0.1 0.044 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 AIF84267.1 - 0.097 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 AIF84267.1 - 0.12 12.1 0.4 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain MobB PF03205.9 AIF84267.1 - 0.16 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0104 PF03706.8 AIF84269.1 - 9.6e-29 100.5 24.8 1.3e-28 100.1 17.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) Snf7 PF03357.16 AIF84271.1 - 1e-07 31.4 0.3 1.6e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 Snf7 DHC_N1 PF08385.7 AIF84271.1 - 0.0002 19.8 0.8 0.00025 19.5 0.6 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 LOH1CR12 PF10158.4 AIF84271.1 - 0.0024 17.6 0.5 0.0041 16.9 0.3 1.3 1 0 0 1 1 1 1 Tumour suppressor protein CK2S PF15011.1 AIF84271.1 - 0.048 13.4 1.1 0.12 12.1 0.6 1.7 1 1 1 2 2 2 0 Casein Kinase 2 substrate Matrilin_ccoil PF10393.4 AIF84271.1 - 0.076 12.3 0.4 0.076 12.3 0.3 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin IFT57 PF10498.4 AIF84271.1 - 0.17 10.6 4.9 0.25 10.0 3.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AHH PF14412.1 AIF84271.1 - 0.18 11.7 1.3 0.29 11.1 0.9 1.4 1 1 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Baculo_PEP_C PF04513.7 AIF84271.1 - 0.23 11.2 2.3 1.2 8.9 0.4 2.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nuc_rec_co-act PF08815.5 AIF84271.1 - 0.53 9.8 2.3 5.7 6.5 0.0 3.3 4 0 0 4 4 4 0 Nuclear receptor coactivator NPV_P10 PF05531.7 AIF84271.1 - 1.2 9.4 4.2 8.8 6.6 0.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Cloacin_immun PF03513.9 AIF84272.1 - 0.0074 16.3 0.2 0.032 14.2 0.1 2.2 2 1 0 2 2 2 1 Cloacin immunity protein HicB PF05534.7 AIF84272.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 HicB family UPF0278 PF08745.6 AIF84272.1 - 0.051 12.8 0.1 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 UPF0278 family ADH_zinc_N PF00107.21 AIF84275.1 - 3.8e-34 117.0 0.2 6.5e-34 116.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIF84275.1 - 1.2e-25 89.3 0.0 2.2e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIF84275.1 - 1e-13 52.2 0.0 2.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 AIF84275.1 - 0.03 13.7 0.2 0.045 13.2 0.2 1.2 1 0 0 1 1 1 0 Putative methyltransferase TrkA_N PF02254.13 AIF84275.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SIS PF01380.17 AIF84277.1 - 2.6e-50 169.4 2.7 2.2e-26 92.0 0.8 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 AIF84277.1 - 8.3e-24 84.0 0.0 1.7e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AIF84277.1 - 4.5e-20 71.6 0.3 3.1e-15 55.7 0.1 3.0 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 AIF84277.1 - 3.9e-17 62.1 0.0 9.7e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.1 AIF84277.1 - 1.2e-06 28.2 4.6 0.0025 17.5 0.1 3.7 2 2 1 3 3 3 2 SIS domain GATase_4 PF13230.1 AIF84277.1 - 2.1e-05 23.3 0.1 3.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DNA_pol_B_exo1 PF03104.14 AIF84277.1 - 0.093 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain HTH_20 PF12840.2 AIF84278.1 - 8.1e-10 38.3 0.0 1.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain S_layer_C PF05124.7 AIF84278.1 - 8.8e-10 38.5 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 S-layer like family, C-terminal region TrmB PF01978.14 AIF84278.1 - 3.4e-06 26.6 0.1 6.7e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AIF84278.1 - 0.0032 17.1 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.15 AIF84278.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_27 PF13463.1 AIF84278.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2250 PF10007.4 AIF84278.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_29 PF13551.1 AIF84278.1 - 0.093 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 AIF84278.1 - 0.13 11.9 0.1 0.38 10.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain S4 PF01479.20 AIF84279.1 - 9.6e-13 47.3 4.9 9.1e-12 44.2 0.1 2.8 3 0 0 3 3 3 2 S4 domain Ribosomal_S4 PF00163.14 AIF84279.1 - 0.00021 21.5 4.4 0.00029 21.1 1.3 2.2 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S13 PF00416.17 AIF84280.1 - 1.2e-28 99.6 0.0 1.5e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PspA_IM30 PF04012.7 AIF84282.1 - 0.00047 19.5 0.6 0.00047 19.5 0.4 2.2 1 1 2 3 3 3 2 PspA/IM30 family WEMBL PF05701.6 AIF84282.1 - 0.0027 16.2 9.8 0.007 14.8 6.8 1.7 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Laminin_II PF06009.7 AIF84282.1 - 0.0052 16.5 9.2 0.062 13.0 0.9 2.7 1 1 1 2 2 2 2 Laminin Domain II GTSE1_N PF15259.1 AIF84282.1 - 0.038 13.9 4.3 1.3 8.9 0.2 2.2 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 DUF948 PF06103.6 AIF84282.1 - 0.048 13.5 4.8 0.7 9.7 0.4 3.3 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) AAA_27 PF13514.1 AIF84282.1 - 0.053 11.2 10.8 0.25 8.9 7.3 1.8 1 1 0 1 1 1 0 AAA domain PLA2G12 PF06951.6 AIF84282.1 - 0.075 12.6 0.4 0.18 11.4 0.3 1.7 1 1 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) ISG65-75 PF11727.3 AIF84282.1 - 0.093 11.7 13.8 0.049 12.6 0.6 2.0 1 1 0 2 2 2 0 Invariant surface glycoprotein FlpD PF02662.11 AIF84282.1 - 0.099 12.3 1.3 12 5.6 0.0 3.0 2 1 1 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF2730 PF10805.3 AIF84282.1 - 0.1 12.3 0.4 0.1 12.3 0.2 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 AIF84282.1 - 0.13 11.3 0.6 0.23 10.6 0.2 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cauli_AT PF03233.8 AIF84282.1 - 0.14 11.8 9.2 0.073 12.7 2.8 2.1 2 0 0 2 2 2 0 Aphid transmission protein CorA PF01544.13 AIF84282.1 - 0.18 10.7 2.6 0.15 11.0 1.0 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 AIF84282.1 - 0.22 11.3 2.3 0.65 9.8 0.5 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.12 AIF84282.1 - 0.23 11.1 9.4 0.34 10.5 0.2 3.7 2 1 1 3 3 3 0 Prefoldin subunit Syntaxin PF00804.20 AIF84282.1 - 0.27 11.4 12.8 3.6e+02 1.3 8.8 3.2 1 1 0 1 1 1 0 Syntaxin DivIC PF04977.10 AIF84282.1 - 0.31 10.5 12.4 0.16 11.4 2.5 3.8 4 1 0 4 4 4 0 Septum formation initiator Rho_Binding PF08912.6 AIF84282.1 - 0.35 11.1 0.1 0.35 11.1 0.1 3.5 2 2 1 3 3 3 0 Rho Binding TelA PF05816.6 AIF84282.1 - 0.49 9.0 12.0 0.14 10.8 3.5 2.1 1 1 0 2 2 2 0 Toxic anion resistance protein (TelA) Prefoldin_2 PF01920.15 AIF84282.1 - 0.55 10.0 12.5 12 5.6 0.6 3.3 2 1 1 3 3 3 0 Prefoldin subunit UPF0184 PF03670.8 AIF84282.1 - 0.66 10.1 5.0 0.21 11.7 0.5 2.5 3 1 0 3 3 1 0 Uncharacterised protein family (UPF0184) SlyX PF04102.7 AIF84282.1 - 0.8 10.1 3.1 6 7.3 0.3 3.2 2 1 1 3 3 3 0 SlyX DUF4446 PF14584.1 AIF84282.1 - 0.87 9.4 6.3 6.4 6.6 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.6 AIF84282.1 - 0.96 9.3 6.9 7.3 6.5 0.6 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.4 AIF84282.1 - 1.1 9.5 7.0 7.3 6.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlaG PF03646.10 AIF84282.1 - 2 8.6 7.2 3.6 7.7 0.6 2.4 2 0 0 2 2 2 0 FlaG protein Bap31 PF05529.7 AIF84282.1 - 2 7.8 8.4 4.4 6.7 1.6 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3496 PF12001.3 AIF84282.1 - 2.4 8.4 5.6 1.8 8.8 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) Uds1 PF15456.1 AIF84282.1 - 2.7 7.9 12.6 3.7 7.5 4.3 3.1 1 1 1 2 2 2 0 Up-regulated During Septation NPV_P10 PF05531.7 AIF84282.1 - 3 8.1 8.8 2.8 8.2 3.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 AIF84282.1 - 5.2 6.3 9.8 1.1 8.5 3.1 2.4 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF4164 PF13747.1 AIF84282.1 - 5.6 7.1 13.5 0.41 10.8 2.2 3.2 2 2 0 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 AIF84282.1 - 5.7 4.6 9.7 0.65 7.7 2.7 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family AAA_5 PF07728.9 AIF84283.1 - 4.2e-10 39.4 0.0 6e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 AIF84283.1 - 1.5e-09 37.5 0.0 9.9e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 AIF84283.1 - 7.5e-07 28.8 0.0 6.6e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 AIF84283.1 - 5.5e-05 22.4 0.0 0.32 10.1 0.0 2.7 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 AIF84283.1 - 0.00016 20.5 0.0 0.0015 17.3 0.0 2.1 1 1 0 1 1 1 1 PrkA AAA domain MCM PF00493.18 AIF84283.1 - 0.00039 19.3 0.0 0.0055 15.5 0.0 2.2 2 0 0 2 2 2 1 MCM2/3/5 family AAA PF00004.24 AIF84283.1 - 0.028 14.6 0.0 0.65 10.1 0.0 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbbQ_C PF08406.5 AIF84283.1 - 0.099 12.6 0.5 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal VWA_2 PF13519.1 AIF84284.1 - 8.1e-11 42.3 0.0 4.8e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain AA_permease_N PF08403.5 AIF84284.1 - 0.12 11.6 0.7 0.34 10.2 0.5 1.7 1 0 0 1 1 1 0 Amino acid permease N-terminal Reprolysin_5 PF13688.1 AIF84285.1 - 4.8e-06 26.6 1.9 4.8e-06 26.6 1.3 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 AIF84285.1 - 0.0017 18.8 3.0 0.0017 18.8 2.1 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 AIF84285.1 - 0.0019 17.8 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.19 AIF84285.1 - 0.0042 16.8 0.3 0.0088 15.7 0.2 1.5 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.3 AIF84285.1 - 0.046 12.1 0.0 0.082 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family DUF4394 PF14339.1 AIF84286.1 - 5.7e-05 22.5 6.4 0.011 15.0 0.1 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4394) NHL PF01436.16 AIF84286.1 - 0.00056 19.7 13.7 7.3 6.7 0.1 6.5 7 0 0 7 7 7 2 NHL repeat Pep3_Vps18 PF05131.9 AIF84286.1 - 0.0018 17.7 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Coatomer_WDAD PF04053.9 AIF84286.1 - 0.0063 15.3 2.6 0.016 14.0 0.8 2.0 2 0 0 2 2 2 1 Coatomer WD associated region AAA_11 PF13086.1 AIF84286.1 - 0.033 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PQQ_3 PF13570.1 AIF84286.1 - 0.082 13.2 6.1 0.8 10.0 0.1 4.0 5 0 0 5 5 5 0 PQQ-like domain PQQ_2 PF13360.1 AIF84286.1 - 0.14 11.6 3.3 1.5 8.2 0.4 3.2 2 1 0 3 3 3 0 PQQ-like domain HAD PF12710.2 AIF84287.1 - 2.3e-10 40.9 0.1 3.1e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIF84287.1 - 1.9e-09 38.2 0.5 7.3e-09 36.3 0.1 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AIF84287.1 - 1.3e-07 32.0 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AIF84287.1 - 0.0002 21.0 0.0 0.00034 20.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIF84287.1 - 0.0014 17.9 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.7 AIF84287.1 - 0.035 13.2 0.0 0.12 11.5 0.0 2.0 1 1 0 1 1 1 0 Putative Phosphatase Ribonuc_L-PSP PF01042.16 AIF84288.1 - 2.9e-27 94.8 0.1 3.2e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP F420_ligase PF01996.11 AIF84289.1 - 3e-70 235.8 1.7 3.4e-70 235.6 1.2 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Abhydrolase_6 PF12697.2 AIF84290.1 - 2.9e-35 122.2 0.0 3.4e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIF84290.1 - 1.3e-23 83.7 0.1 3.9e-23 82.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIF84290.1 - 1.1e-17 64.0 0.0 7.4e-17 61.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AIF84290.1 - 1.4e-08 34.4 0.0 9.8e-07 28.5 0.0 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 AIF84290.1 - 2.4e-05 24.6 0.0 2.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 AIF84290.1 - 2.5e-05 23.8 0.0 0.0045 16.4 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 AIF84290.1 - 0.00025 20.9 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF1057 PF06342.7 AIF84290.1 - 0.00049 19.0 0.0 0.00075 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.13 AIF84290.1 - 0.00054 19.3 0.0 0.097 11.9 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.20 AIF84290.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.16 AIF84290.1 - 0.001 18.3 0.1 1 8.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 AIF84290.1 - 0.002 16.7 1.3 0.2 10.1 0.1 2.9 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Ser_hydrolase PF06821.8 AIF84290.1 - 0.0037 16.9 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase COesterase PF00135.23 AIF84290.1 - 0.016 13.9 0.0 0.05 12.3 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S15 PF02129.13 AIF84290.1 - 0.018 14.4 0.0 5.7 6.2 0.0 2.8 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 AIF84290.1 - 0.027 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 AIF84290.1 - 0.048 13.0 1.0 0.085 12.2 0.7 1.6 1 1 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 AIF84290.1 - 0.061 12.9 1.3 0.74 9.3 0.9 2.3 1 1 0 1 1 1 0 PGAP1-like protein LIP PF03583.9 AIF84290.1 - 0.1 11.7 0.0 1.7 7.7 0.0 2.1 1 1 0 1 1 1 0 Secretory lipase VirJ PF06057.6 AIF84290.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF915 PF06028.6 AIF84290.1 - 0.14 11.2 0.1 0.39 9.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) TusA PF01206.12 AIF84291.1 - 1.9e-23 81.8 0.0 2.1e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.4 AIF84291.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) PALP PF00291.20 AIF84292.1 - 6.4e-55 186.5 0.0 8.5e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CcmE PF03100.10 AIF84292.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 CcmE CARDB PF07705.6 AIF84293.1 - 0.055 13.5 1.7 0.6 10.1 0.2 2.8 3 1 0 3 3 3 0 CARDB MCE PF02470.15 AIF84293.1 - 0.075 13.0 0.1 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 mce related protein Pyr_redox_2 PF07992.9 AIF84294.1 - 1.8e-33 116.1 4.7 8.3e-32 110.6 3.2 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AIF84294.1 - 2.8e-19 69.3 3.7 2.8e-19 69.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIF84294.1 - 3.6e-18 66.3 0.3 1.3e-14 54.7 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AIF84294.1 - 4.5e-10 38.9 3.6 0.00012 21.1 0.0 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 AIF84294.1 - 5.2e-07 28.8 0.1 0.0064 15.4 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 AIF84294.1 - 1.7e-06 27.1 7.3 0.00025 20.0 0.3 4.2 2 2 3 5 5 5 2 FAD binding domain GIDA PF01134.17 AIF84294.1 - 4.2e-06 25.8 5.3 0.04 12.7 0.1 4.5 3 2 2 5 5 5 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 AIF84294.1 - 2.2e-05 23.6 2.2 0.25 10.3 0.1 3.2 2 1 1 3 3 3 2 FAD binding domain Thi4 PF01946.12 AIF84294.1 - 2.6e-05 23.4 0.4 0.0019 17.3 0.1 2.6 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.2 AIF84294.1 - 6.2e-05 22.2 0.9 0.0086 15.1 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 AIF84294.1 - 6.4e-05 23.1 0.5 0.02 15.1 0.5 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 AIF84294.1 - 0.00025 19.6 1.4 0.03 12.7 0.1 3.2 3 1 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 AIF84294.1 - 0.00036 20.4 0.1 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AIF84294.1 - 0.0086 15.0 0.5 0.9 8.3 0.1 3.1 3 1 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 AIF84294.1 - 0.0092 15.7 0.9 0.63 9.8 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF4624 PF15417.1 AIF84294.1 - 0.03 13.9 0.1 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4624) Trp_halogenase PF04820.9 AIF84294.1 - 0.038 12.6 0.6 2.4 6.6 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.15 AIF84294.1 - 0.04 14.0 0.2 0.4 10.7 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase TFIIB PF00382.14 AIF84296.1 - 7e-30 102.6 4.2 2.8e-16 59.0 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Rrf2 PF02082.15 AIF84296.1 - 0.00044 20.3 0.0 10 6.2 0.0 3.3 3 0 0 3 3 3 2 Transcriptional regulator Cyclin_N PF00134.18 AIF84296.1 - 0.0045 16.5 0.1 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_23 PF13384.1 AIF84296.1 - 0.047 13.3 0.2 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain ORC6 PF05460.8 AIF84296.1 - 0.18 10.8 0.4 0.35 9.9 0.2 1.5 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF2087 PF09860.4 AIF84298.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF2805 PF10985.3 AIF84298.1 - 0.032 14.1 0.1 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Guanylate_cyc PF00211.15 AIF84299.1 - 1.3e-15 57.2 0.0 1.7e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Terminase_5 PF06056.7 AIF84299.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) AP4E_app_platf PF14807.1 AIF84299.1 - 0.041 14.1 0.1 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform AsnC_trans_reg PF01037.16 AIF84300.1 - 4.1e-09 36.0 0.1 6e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 AsnC family PKD PF00801.15 AIF84300.1 - 0.031 14.0 0.2 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 PKD domain Radical_SAM PF04055.16 AIF84301.1 - 5.8e-10 39.5 0.4 2e-09 37.8 0.2 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 AIF84301.1 - 1.2e-06 28.5 0.1 2.4e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AIF84301.1 - 2.5e-06 27.6 0.1 5.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DHquinase_II PF01220.14 AIF84302.1 - 0.021 14.1 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Dehydroquinase class II MMR_HSR1 PF01926.18 AIF84305.1 - 2.8e-08 33.7 0.1 3.6e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AIF84305.1 - 0.0052 16.2 0.5 0.0083 15.5 0.4 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IDO PF01231.13 AIF84305.1 - 0.044 12.2 0.0 0.044 12.2 0.0 1.0 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase PduV-EutP PF10662.4 AIF84305.1 - 0.053 13.0 0.5 0.099 12.1 0.4 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AsnC_trans_reg PF01037.16 AIF84306.1 - 5.8e-05 22.7 0.0 6.3e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 AsnC family EURL PF06937.6 AIF84306.1 - 0.092 12.1 0.0 0.092 12.1 0.0 1.0 1 0 0 1 1 1 0 EURL protein zf-C2HC5 PF06221.8 AIF84307.1 - 0.041 13.6 0.3 0.063 13.0 0.2 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type XPA_N PF01286.13 AIF84307.1 - 0.32 10.6 1.9 14 5.5 0.3 2.9 3 0 0 3 3 3 0 XPA protein N-terminal SNARE_assoc PF09335.6 AIF84309.1 - 2.1e-16 60.2 1.0 3.1e-16 59.6 0.7 1.3 1 0 0 1 1 1 1 SNARE associated Golgi protein RseC_MucC PF04246.7 AIF84309.1 - 0.24 10.9 1.0 19 4.8 0.0 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MscS_TM PF12794.2 AIF84309.1 - 0.74 8.3 3.5 1.7 7.1 0.0 2.5 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 HTH_45 PF14947.1 AIF84310.1 - 9.7e-13 47.7 0.3 1e-12 47.6 0.2 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF84310.1 - 0.0074 15.9 0.2 0.0088 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) APC2 PF08672.6 AIF84310.1 - 0.023 14.9 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Thi4 PF01946.12 AIF84311.1 - 1.6e-62 210.6 0.0 1.9e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 AIF84311.1 - 2.4e-12 46.4 1.0 1.9e-07 30.2 0.2 2.7 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 AIF84311.1 - 7.2e-10 38.5 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AIF84311.1 - 9.5e-09 34.6 1.1 1.7e-05 23.8 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AIF84311.1 - 5.3e-08 32.3 0.1 7.6e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AIF84311.1 - 9.4e-08 31.9 0.1 1.9e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AIF84311.1 - 4.1e-07 30.0 0.1 8.1e-07 29.1 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AIF84311.1 - 5.5e-06 25.1 0.1 7.5e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 AIF84311.1 - 3.4e-05 24.0 0.1 5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIF84311.1 - 9.4e-05 21.4 0.5 0.0007 18.6 0.4 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 AIF84311.1 - 0.00019 20.3 0.8 0.0003 19.7 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 AIF84311.1 - 0.0011 17.7 0.3 0.41 9.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase ThiF PF00899.16 AIF84311.1 - 0.0089 15.8 0.4 0.028 14.2 0.1 1.9 2 1 1 3 3 3 1 ThiF family Amino_oxidase PF01593.19 AIF84311.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 AIF84311.1 - 0.052 13.3 0.2 0.099 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 AIF84311.1 - 0.094 13.1 0.5 0.36 11.2 0.3 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_5 PF07994.7 AIF84314.1 - 1.5e-26 93.5 0.0 4.3e-25 88.8 0.0 2.0 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 AIF84314.1 - 1.8e-13 50.2 0.0 3.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase GFO_IDH_MocA PF01408.17 AIF84314.1 - 0.087 13.3 0.3 0.97 9.9 0.2 2.7 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.14 AIF84314.1 - 0.14 12.6 1.4 5 7.7 0.0 2.8 1 1 1 2 2 2 0 CoA binding domain TPR_1 PF00515.23 AIF84315.1 - 9.3e-30 101.0 3.9 1.5e-13 49.7 1.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 AIF84315.1 - 1.5e-28 98.2 4.6 2.8e-17 62.1 0.4 3.2 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 AIF84315.1 - 1.9e-26 89.7 3.2 1.3e-10 40.3 0.4 5.2 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AIF84315.1 - 1.1e-18 65.7 1.2 4.1e-06 26.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AIF84315.1 - 3.5e-16 59.3 0.0 3.7e-06 27.4 0.0 4.2 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AIF84315.1 - 3.8e-14 51.3 7.0 1.7e-08 33.6 0.3 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AIF84315.1 - 2.8e-13 49.5 0.1 1.1e-05 25.1 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIF84315.1 - 2.3e-12 47.0 0.0 1.6e-05 25.1 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AIF84315.1 - 8.2e-12 44.8 0.1 3.3e-07 30.1 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AIF84315.1 - 5e-10 39.3 7.5 1.9e-05 24.7 0.9 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AIF84315.1 - 2.1e-09 37.1 0.0 0.00052 20.4 0.0 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 AIF84315.1 - 1.6e-07 30.5 0.1 0.0025 17.4 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIF84315.1 - 4.1e-07 29.7 0.2 0.005 16.6 0.0 3.2 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AIF84315.1 - 3.7e-05 23.8 0.9 0.062 13.7 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat NARP1 PF12569.3 AIF84315.1 - 0.0043 15.8 0.3 2.4 6.7 0.0 2.3 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 AIF84315.1 - 0.01 15.9 0.0 0.06 13.4 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.1 AIF84315.1 - 0.036 13.5 0.1 0.42 10.0 0.1 2.2 1 1 1 2 2 2 0 Outer membrane lipoprotein DUF2250 PF10007.4 AIF84315.1 - 0.066 13.1 0.2 0.21 11.5 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) AA_kinase PF00696.23 AIF84317.1 - 5.5e-28 98.1 1.4 6.6e-28 97.8 1.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family FMN_dh PF01070.13 AIF84318.1 - 4.1e-30 104.8 0.1 3.6e-21 75.4 0.1 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 AIF84318.1 - 0.00019 20.5 3.0 0.00034 19.6 2.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 AIF84318.1 - 0.0068 15.6 0.7 0.017 14.3 0.1 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 AIF84318.1 - 0.0075 15.2 4.8 0.015 14.2 0.2 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain polyprenyl_synt PF00348.12 AIF84319.1 - 4.7e-62 209.1 0.0 6.1e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase BUD22 PF09073.5 AIF84319.1 - 0.1 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 BUD22 tRNA-synt_1c PF00749.16 AIF84320.1 - 7.7e-76 254.7 0.0 9.9e-76 254.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AIF84320.1 - 1.3e-32 112.8 0.0 2.3e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain FAA_hydrolase PF01557.13 AIF84321.1 - 3.8e-65 219.4 0.0 5.6e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SIMPL PF04402.9 AIF84322.1 - 6.1e-29 101.3 7.9 3.1e-20 72.9 0.3 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF541) Flg_hook PF02120.11 AIF84322.1 - 0.054 13.1 0.0 6.3 6.5 0.0 2.8 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK FMN_red PF03358.10 AIF84323.1 - 5e-29 100.7 0.0 6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AIF84323.1 - 1.3e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Usp PF00582.21 AIF84323.1 - 0.0036 17.4 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family Flavodoxin_5 PF12724.2 AIF84323.1 - 0.0052 16.8 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain Nsp3_PL2pro PF12124.3 AIF84323.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain HTH_20 PF12840.2 AIF84324.1 - 9.5e-16 57.3 0.1 1.5e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF84324.1 - 6.6e-15 54.5 0.1 1.2e-14 53.6 0.0 1.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF84324.1 - 0.0018 17.8 0.4 0.0033 17.0 0.2 1.4 1 1 0 1 1 1 1 MarR family HxlR PF01638.12 AIF84324.1 - 0.0026 17.3 0.0 0.0062 16.1 0.0 1.7 1 1 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.14 AIF84324.1 - 0.0046 16.6 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AIF84324.1 - 0.022 14.1 0.0 0.067 12.5 0.0 2.0 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2513 PF10711.4 AIF84324.1 - 0.05 13.6 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_1 PF00126.22 AIF84324.1 - 0.077 12.7 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family AHSA1 PF08327.6 AIF84325.1 - 6.7e-18 64.9 0.0 9.6e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 AIF84325.1 - 5e-08 33.2 0.3 6.6e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF84325.1 - 0.012 15.6 0.6 0.13 12.2 0.3 2.5 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF1192 PF06698.6 AIF84327.1 - 0.082 12.7 0.7 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4164 PF13747.1 AIF84327.1 - 0.48 10.6 3.0 3.1 8.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) NAD_binding_1 PF00175.16 AIF84328.1 - 1.9e-12 47.6 0.0 4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AIF84328.1 - 1.3e-11 44.4 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIF84328.1 - 0.052 13.4 0.1 0.16 11.8 0.0 1.7 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Radical_SAM PF04055.16 AIF84330.1 - 2.1e-12 47.5 0.0 3.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.14 AIF84330.1 - 0.036 13.9 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain NUDIX PF00293.23 AIF84331.1 - 5.4e-18 64.9 0.0 6.8e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 AIF84331.1 - 0.012 14.9 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Imm45 PF15603.1 AIF84331.1 - 0.075 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 45 DUF98 PF01947.11 AIF84332.1 - 0.0059 16.3 0.5 0.25 11.0 0.4 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF98) DUF2651 PF10852.3 AIF84333.1 - 0.013 15.8 2.1 0.035 14.4 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) Ubie_methyltran PF01209.13 AIF84334.1 - 2.8e-19 69.1 0.0 3.4e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AIF84334.1 - 1.2e-17 64.1 0.0 2.3e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84334.1 - 1.1e-11 45.0 0.0 2.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84334.1 - 1.9e-11 43.9 0.0 2.7e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF84334.1 - 1.3e-10 41.3 0.8 8.4e-10 38.7 0.4 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84334.1 - 3.5e-09 36.4 0.0 5.8e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84334.1 - 6.9e-09 36.2 0.1 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84334.1 - 5.1e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 AIF84334.1 - 8.6e-06 25.2 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 AIF84334.1 - 9.2e-06 24.9 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 AIF84334.1 - 0.0024 18.7 0.0 0.0042 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AIF84334.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 AIF84334.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FmrO PF07091.6 AIF84334.1 - 0.014 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) UBA PF00627.26 AIF84334.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Pyridox_oxidase PF01243.15 AIF84335.1 - 1.6e-12 47.2 0.0 2.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF84335.1 - 1.6e-05 24.7 0.0 2.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Kdo PF06293.9 AIF84336.1 - 0.037 13.0 0.0 0.057 12.4 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C65 PF10275.4 AIF84337.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain DUF1090 PF06476.7 AIF84338.1 - 5.2e-05 22.8 11.5 5.2e-05 22.8 8.0 3.7 1 1 2 4 4 4 2 Protein of unknown function (DUF1090) Reo_sigmaC PF04582.7 AIF84338.1 - 0.0058 15.8 2.0 0.65 9.1 0.3 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein KNOX2 PF03791.8 AIF84338.1 - 0.012 14.8 0.3 0.058 12.6 0.2 2.2 1 0 0 1 1 1 0 KNOX2 domain UPF0058 PF01893.11 AIF84338.1 - 0.022 14.8 2.2 0.022 14.8 1.5 2.6 2 1 1 3 3 2 0 Uncharacterised protein family UPF0058 YqzH PF14164.1 AIF84338.1 - 0.051 13.4 1.0 0.38 10.7 0.2 2.9 1 1 1 2 2 2 0 YqzH-like protein DUF869 PF05911.6 AIF84338.1 - 0.067 11.4 39.0 0.092 10.9 18.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) NPV_P10 PF05531.7 AIF84338.1 - 0.13 12.5 10.5 17 5.7 2.4 4.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Not1 PF04054.10 AIF84338.1 - 0.14 11.0 3.1 0.12 11.2 1.0 1.5 1 1 0 1 1 1 0 CCR4-Not complex component, Not1 Laminin_II PF06009.7 AIF84338.1 - 0.36 10.5 21.6 1.9 8.2 6.0 3.2 1 1 2 3 3 3 0 Laminin Domain II Allexi_40kDa PF05549.6 AIF84338.1 - 0.95 8.7 22.2 0.44 9.8 2.6 3.1 1 1 2 3 3 3 0 Allexivirus 40kDa protein COG2 PF06148.6 AIF84338.1 - 1.3 8.9 28.7 0.18 11.6 1.9 4.1 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-Q PF13094.1 AIF84338.1 - 2.6 8.0 38.7 0.039 13.9 13.1 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0184 PF03670.8 AIF84338.1 - 3.9 7.7 9.1 0.43 10.7 0.7 3.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0184) IncA PF04156.9 AIF84338.1 - 4.4 6.8 38.7 0.28 10.7 11.6 3.0 1 1 1 2 2 2 0 IncA protein DUF948 PF06103.6 AIF84338.1 - 4.6 7.1 16.0 2.2 8.1 0.1 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Molydop_binding PF01568.16 AIF84339.1 - 0.01 15.6 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain EB PF01683.13 AIF84340.1 - 1.3 9.1 7.0 1.8 8.6 4.9 1.3 1 0 0 1 1 1 0 EB module DUF1512 PF07431.7 AIF84341.1 - 3e-105 351.8 13.3 3.7e-105 351.5 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) OrfB_Zn_ribbon PF07282.6 AIF84342.1 - 0.0044 16.6 5.4 0.021 14.4 3.8 1.8 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 AIF84342.1 - 0.0052 16.4 1.0 0.016 14.8 0.7 1.7 1 1 1 2 2 2 1 Nudix N-terminal TF_Zn_Ribbon PF08271.7 AIF84342.1 - 0.015 14.5 2.7 2.6 7.4 0.3 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 AIF84342.1 - 0.021 14.2 2.4 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 AIF84342.1 - 0.024 13.8 0.8 5.2 6.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AIF84342.1 - 0.027 14.4 1.6 2.8 7.9 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 AIF84342.1 - 0.064 13.0 2.0 0.12 12.1 1.4 1.5 1 1 0 1 1 1 0 Double zinc ribbon YhfH PF14149.1 AIF84342.1 - 0.076 12.8 1.8 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein zf-IS66 PF13005.2 AIF84342.1 - 0.08 12.9 1.7 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 C1_1 PF00130.17 AIF84342.1 - 0.088 12.5 1.5 0.51 10.1 1.1 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ISL3 PF14690.1 AIF84342.1 - 0.1 12.6 0.4 11 6.1 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.1 AIF84342.1 - 0.13 11.7 3.5 6.8 6.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 AIF84342.1 - 0.24 11.1 2.1 0.61 9.8 1.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 AIF84342.1 - 0.29 10.9 3.2 1.4 8.7 2.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2H2_3 PF13878.1 AIF84342.1 - 0.48 10.0 1.9 19 4.9 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn_Tnp_IS1595 PF12760.2 AIF84342.1 - 0.48 10.2 3.0 3.9 7.3 2.1 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-DNL PF05180.7 AIF84342.1 - 0.5 10.1 3.8 2.7 7.7 0.1 2.1 1 1 1 2 2 2 0 DNL zinc finger Zn_ribbon_recom PF13408.1 AIF84342.1 - 1.5 9.1 5.1 29 5.0 3.5 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Peptidase_M24 PF00557.19 AIF84343.1 - 1.2e-39 136.0 0.3 1.3e-39 135.9 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF917 PF06032.7 AIF84343.1 - 0.057 11.9 0.1 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF917) Peptidase_M10 PF00413.19 AIF84344.1 - 4.2e-05 23.3 0.1 5.9e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 AIF84344.1 - 0.0015 17.4 0.3 0.0024 16.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 AIF84344.1 - 0.011 16.2 0.1 0.02 15.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 AIF84344.1 - 0.019 14.4 0.1 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3152) BSP PF04450.7 AIF84344.1 - 0.13 11.7 0.3 0.2 11.1 0.0 1.4 2 0 0 2 2 2 0 Peptidase of plants and bacteria YfhO PF09586.5 AIF84344.1 - 0.15 10.0 0.3 0.2 9.6 0.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Metallopep PF12044.3 AIF84344.1 - 0.21 9.9 0.6 0.31 9.4 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase family P-II PF00543.17 AIF84345.1 - 2.1e-28 98.7 0.0 2.4e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II T2SE PF00437.15 AIF84346.1 - 2.4e-12 46.3 0.0 7.8e-12 44.6 0.0 2.0 1 1 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.24 AIF84346.1 - 8e-11 41.4 2.6 9.6e-11 41.1 0.2 2.5 3 0 0 3 3 1 1 KH domain KH_3 PF13014.1 AIF84346.1 - 4e-08 32.7 0.1 2.8e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 KH domain AAA_17 PF13207.1 AIF84346.1 - 8.5e-06 26.5 0.0 4.1e-05 24.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain PIN_4 PF13638.1 AIF84346.1 - 1.8e-05 24.8 0.2 0.0001 22.4 0.2 2.1 1 1 0 1 1 1 1 PIN domain AAA_16 PF13191.1 AIF84346.1 - 2.9e-05 24.1 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 AIF84346.1 - 3.7e-05 22.6 0.0 7.6e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 AIF84346.1 - 5.6e-05 23.4 0.0 0.0002 21.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 AIF84346.1 - 7.5e-05 22.2 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KH_2 PF07650.12 AIF84346.1 - 0.00017 21.0 0.2 0.00082 18.8 0.1 2.2 1 0 0 1 1 1 1 KH domain AAA_14 PF13173.1 AIF84346.1 - 0.00025 20.9 0.0 0.00092 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AIF84346.1 - 0.00086 19.6 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 AIF84346.1 - 0.001 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 AIF84346.1 - 0.0015 18.2 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 AIF84346.1 - 0.002 17.8 0.0 0.0049 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 AIF84346.1 - 0.0042 16.8 0.2 0.024 14.3 0.0 2.4 3 0 0 3 3 2 1 NTPase Zeta_toxin PF06414.7 AIF84346.1 - 0.0046 16.0 0.1 0.01 14.9 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 AIF84346.1 - 0.005 16.9 0.1 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIF84346.1 - 0.0057 16.5 0.1 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AIF84346.1 - 0.0059 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0278 PF08745.6 AIF84346.1 - 0.0091 15.2 0.1 0.029 13.6 0.0 1.9 1 0 0 1 1 1 1 UPF0278 family AAA_10 PF12846.2 AIF84346.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain KTI12 PF08433.5 AIF84346.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KH_4 PF13083.1 AIF84346.1 - 0.012 15.2 0.2 0.096 12.3 0.0 2.6 2 0 0 2 2 2 0 KH domain ATP_bind_1 PF03029.12 AIF84346.1 - 0.014 14.9 0.1 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 AIF84346.1 - 0.014 14.8 0.0 0.051 13.1 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 AIF84346.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AIF84346.1 - 0.019 15.1 0.1 0.075 13.2 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AIF84346.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KH_5 PF13184.1 AIF84346.1 - 0.027 14.2 0.1 0.086 12.6 0.1 1.9 1 0 0 1 1 1 0 NusA-like KH domain Mg_chelatase PF01078.16 AIF84346.1 - 0.031 13.4 0.1 0.081 12.0 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 AIF84346.1 - 0.043 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PPV_E1_C PF00519.12 AIF84346.1 - 0.047 12.2 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.17 AIF84346.1 - 0.05 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.12 AIF84346.1 - 0.065 12.5 0.0 0.21 10.9 0.0 1.8 1 1 1 2 2 2 0 Thymidylate kinase MMR_HSR1 PF01926.18 AIF84346.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 AIF84346.1 - 0.075 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 AIF84346.1 - 0.09 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 AIF84346.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DAP3 PF10236.4 AIF84346.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Fe_dep_repress PF01325.14 AIF84347.1 - 7.3e-22 77.0 1.7 1.4e-21 76.2 0.5 1.9 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.10 AIF84347.1 - 5.3e-14 51.6 0.8 1.3e-13 50.3 0.6 1.7 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_24 PF13412.1 AIF84347.1 - 7.9e-06 25.1 0.1 1.7e-05 24.0 0.0 1.6 2 0 0 2 2 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AIF84347.1 - 1.4e-05 24.6 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AIF84347.1 - 3.9e-05 23.9 0.1 0.00013 22.1 0.0 2.0 2 1 1 3 3 2 1 Winged helix DNA-binding domain TrmB PF01978.14 AIF84347.1 - 4e-05 23.2 0.1 7.6e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AIF84347.1 - 0.00022 20.7 0.0 0.00053 19.5 0.0 1.7 1 0 0 1 1 1 1 HTH domain LexA_DNA_bind PF01726.11 AIF84347.1 - 0.00026 20.4 0.0 0.00068 19.1 0.0 1.7 2 0 0 2 2 2 1 LexA DNA binding domain FeoC PF09012.5 AIF84347.1 - 0.00032 20.3 0.0 0.0009 18.9 0.0 1.7 2 0 0 2 2 2 1 FeoC like transcriptional regulator MarR PF01047.17 AIF84347.1 - 0.00035 20.2 0.0 0.00097 18.8 0.0 1.7 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 AIF84347.1 - 0.0019 18.2 0.1 0.003 17.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_DeoR PF08220.7 AIF84347.1 - 0.0046 16.4 0.1 0.026 14.0 0.0 2.2 2 1 1 3 3 2 1 DeoR-like helix-turn-helix domain TFIIE_alpha PF02002.12 AIF84347.1 - 0.0072 15.8 0.1 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 TFIIE alpha subunit EAP30 PF04157.11 AIF84347.1 - 0.01 14.9 0.4 0.014 14.5 0.0 1.4 2 0 0 2 2 2 0 EAP30/Vps36 family DUF977 PF06163.6 AIF84347.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) TALPID3 PF15324.1 AIF84347.1 - 0.011 13.1 0.1 0.012 13.0 0.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target HTH_Crp_2 PF13545.1 AIF84347.1 - 0.014 15.1 0.0 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_37 PF13744.1 AIF84347.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4423 PF14394.1 AIF84347.1 - 0.031 13.8 0.0 0.056 12.9 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) DUF2250 PF10007.4 AIF84347.1 - 0.032 14.1 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PAX PF00292.13 AIF84347.1 - 0.038 13.7 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_1 PF00126.22 AIF84347.1 - 0.054 13.2 0.2 0.29 10.9 0.0 2.2 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF2042 PF09743.4 AIF84347.1 - 0.067 12.4 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Penicillinase_R PF03965.11 AIF84347.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor HTH_6 PF01418.12 AIF84347.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_34 PF13601.1 AIF84347.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_5 PF01022.15 AIF84347.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Rhodanese PF00581.15 AIF84348.1 - 5.3e-43 145.9 0.2 2.5e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SIS PF01380.17 AIF84349.1 - 1.1e-11 44.4 1.9 8.6e-06 25.3 0.8 3.1 2 1 0 2 2 2 2 SIS domain SIS_2 PF13580.1 AIF84349.1 - 0.0042 16.7 1.9 0.0051 16.5 0.1 2.0 2 0 0 2 2 2 1 SIS domain AsnC_trans_reg PF01037.16 AIF84350.1 - 2.7e-12 46.2 0.1 2.9e-12 46.0 0.1 1.0 1 0 0 1 1 1 1 AsnC family META PF03724.11 AIF84351.1 - 4.8e-09 35.9 0.0 5.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 META domain AcetylCoA_hyd_C PF13336.1 AIF84351.1 - 0.018 14.7 0.1 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Methyltransf_31 PF13847.1 AIF84352.1 - 4.7e-17 61.9 0.0 7.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF84352.1 - 3.6e-15 56.2 0.0 7.9e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84352.1 - 1.1e-10 41.7 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84352.1 - 3.7e-10 40.1 0.0 9.8e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84352.1 - 8e-10 38.6 0.0 3.8e-09 36.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84352.1 - 1.1e-09 38.8 0.0 2.8e-09 37.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF84352.1 - 1.2e-07 31.1 0.0 2e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 AIF84352.1 - 0.0011 18.0 0.0 0.0028 16.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 AIF84352.1 - 0.0064 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 AIF84352.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.6 AIF84352.1 - 0.04 12.6 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Trm112p PF03966.11 AIF84352.1 - 0.042 14.2 0.1 0.087 13.2 0.1 1.6 1 0 0 1 1 1 0 Trm112p-like protein PCMT PF01135.14 AIF84352.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RXT2_N PF08595.6 AIF84353.1 - 0.033 13.9 0.6 0.068 12.9 0.2 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF771 PF05595.6 AIF84353.1 - 0.049 13.5 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF771) FixG_C PF11614.3 AIF84354.1 - 0.02 14.9 0.3 4.2 7.4 0.0 2.6 1 1 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF1180 PF06679.7 AIF84354.1 - 8.6 6.2 9.1 14 5.5 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) GerE PF00196.14 AIF84355.1 - 0.00047 19.4 0.1 0.001 18.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.1 AIF84355.1 - 0.0016 17.8 1.0 0.0034 16.7 0.6 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 AIF84355.1 - 0.0019 17.8 0.1 0.0049 16.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain AsnC_trans_reg PF01037.16 AIF84355.1 - 0.0046 16.6 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 AsnC family DELLA PF12041.3 AIF84355.1 - 0.0065 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator DELLA protein N terminal HTH_AsnC-type PF13404.1 AIF84355.1 - 0.0091 15.5 1.1 0.039 13.4 0.8 2.0 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.7 AIF84355.1 - 0.0099 15.3 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.1 AIF84355.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HMA PF00403.21 AIF84355.1 - 0.086 13.0 0.3 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 Heavy-metal-associated domain DUF2089 PF09862.4 AIF84355.1 - 0.12 12.2 0.2 0.5 10.1 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2089) ADK PF00406.17 AIF84356.1 - 0.0062 16.4 0.0 0.0082 16.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase HTH_AsnC-type PF13404.1 AIF84356.1 - 0.031 13.7 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AIF84356.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Mga PF05043.8 AIF84356.1 - 0.14 12.4 0.3 0.32 11.2 0.1 1.6 2 0 0 2 2 2 0 Mga helix-turn-helix domain Alba PF01918.16 AIF84357.1 - 7.5e-10 38.2 0.1 9.8e-10 37.8 0.1 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 AIF84357.1 - 0.066 12.8 1.0 0.9 9.1 0.1 2.2 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P DUF790 PF05626.6 AIF84358.1 - 0.0097 14.4 0.0 0.028 12.9 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF790) Aminotran_4 PF01063.14 AIF84359.1 - 3.7e-44 150.9 0.0 4.5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV GFO_IDH_MocA PF01408.17 AIF84360.1 - 1.2e-25 90.4 0.0 2.3e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AIF84360.1 - 6.6e-07 29.1 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IlvN PF07991.7 AIF84360.1 - 6.3e-05 22.4 0.3 0.00036 19.9 0.0 2.2 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 AIF84360.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AIF84360.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 AIF84360.1 - 0.0064 15.6 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AIF84360.1 - 0.0089 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 AIF84360.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.19 AIF84360.1 - 0.068 13.4 0.1 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ThiF PF00899.16 AIF84360.1 - 0.074 12.8 2.5 0.1 12.4 0.9 1.9 2 1 0 2 2 2 0 ThiF family Trm112p PF03966.11 AIF84361.1 - 7.8e-08 32.5 0.3 2.2e-07 31.1 0.2 1.7 1 1 0 1 1 1 1 Trm112p-like protein Hexapep PF00132.19 AIF84362.1 - 1.7e-25 87.3 17.9 1.7e-08 33.5 2.5 3.5 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AIF84362.1 - 1.3e-17 62.9 13.1 1.9e-09 36.8 2.0 4.2 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase 2-Hacid_dh_C PF02826.14 AIF84363.1 - 5.8e-65 217.7 0.1 8.3e-65 217.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AIF84363.1 - 5.1e-28 97.1 0.0 8.5e-28 96.4 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AIF84363.1 - 0.00011 22.0 0.1 0.00028 20.7 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 AIF84363.1 - 0.0019 17.6 0.4 0.013 14.8 0.0 2.3 2 1 1 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 AIF84363.1 - 0.002 18.5 0.0 0.006 16.9 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 AIF84363.1 - 0.017 15.1 0.1 0.049 13.6 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding Vip3A_N PF12495.3 AIF84364.1 - 0.00018 21.2 0.1 0.00018 21.2 0.1 1.1 1 0 0 1 1 1 1 Vegetative insecticide protein 3A N terminal DASH_Dad1 PF08649.5 AIF84364.1 - 0.0068 16.0 0.2 0.0094 15.6 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad1 L27 PF02828.11 AIF84364.1 - 0.053 13.2 1.6 1.5 8.5 0.3 2.1 1 1 1 2 2 2 0 L27 domain TBCA PF02970.11 AIF84364.1 - 0.097 12.7 0.2 0.099 12.7 0.1 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF948 PF06103.6 AIF84364.1 - 0.13 12.1 0.3 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Dam1 PF08653.5 AIF84364.1 - 0.3 10.8 2.7 1.2 8.9 0.4 2.0 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF354 PF04007.7 AIF84365.1 - 4.6e-51 173.6 0.0 5.5e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Glyco_trans_4_4 PF13579.1 AIF84365.1 - 0.0036 17.4 0.3 0.013 15.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_28 PF03033.15 AIF84365.1 - 0.0051 16.5 0.1 0.018 14.8 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain LpxB PF02684.10 AIF84365.1 - 0.0064 15.1 0.0 0.0083 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.14 AIF84365.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyco_tran_28_C PF04101.11 AIF84365.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.15 AIF84365.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferases group 1 CutA1 PF03091.10 AIF84367.1 - 3.5e-28 97.2 0.0 4.1e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Ribosomal_L11 PF00298.14 AIF84367.1 - 0.0019 18.3 0.0 0.0073 16.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain eRF1_1 PF03463.10 AIF84368.1 - 3.1e-22 78.5 0.1 5.6e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 AIF84368.1 - 2.3e-11 43.9 0.5 9.7e-11 41.9 0.2 2.2 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.10 AIF84368.1 - 6.7e-07 29.6 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 Fe_dep_repr_C PF02742.10 AIF84370.1 - 2.9e-20 71.7 0.2 4.7e-20 71.0 0.2 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.14 AIF84370.1 - 1.6e-14 53.5 0.4 3e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.15 AIF84370.1 - 4.3e-05 23.0 0.2 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.15 AIF84370.1 - 9.8e-05 22.4 0.1 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.2 AIF84370.1 - 0.0001 21.8 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_1 PF00126.22 AIF84370.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_27 PF13463.1 AIF84370.1 - 0.00089 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 AIF84370.1 - 0.00094 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.1 AIF84370.1 - 0.0017 18.0 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 AIF84370.1 - 0.0036 16.9 0.1 0.0063 16.1 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.1 AIF84370.1 - 0.0063 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_37 PF13744.1 AIF84370.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_assoc_C PF09821.4 AIF84370.1 - 0.013 15.8 0.1 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 C-terminal AAA-associated domain HTH_20 PF12840.2 AIF84370.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 AIF84370.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain IF2_N PF04760.10 AIF84370.1 - 0.033 13.8 0.6 0.13 11.8 0.0 2.1 2 1 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_6 PF01418.12 AIF84370.1 - 0.043 13.5 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HrcA_DNA-bdg PF03444.10 AIF84370.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding NLPC_P60 PF00877.14 AIF84370.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family P53_tetramer PF07710.6 AIF84370.1 - 0.096 11.7 0.3 6.6 5.9 0.1 2.5 2 0 0 2 2 2 0 P53 tetramerisation motif TFIIE_beta PF02186.10 AIF84370.1 - 0.099 12.6 0.2 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain HTH_34 PF13601.1 AIF84370.1 - 0.11 12.5 0.1 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 AIF84371.1 - 1.4e-22 79.1 0.0 4.6e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AIF84371.1 - 4.4e-08 32.3 0.0 6.2e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.5 AIF84371.1 - 3.8e-05 23.1 0.0 9.8e-05 21.8 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.17 AIF84371.1 - 8.6e-05 22.1 0.0 0.0003 20.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 AIF84371.1 - 0.00028 20.2 0.0 0.0006 19.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 AIF84371.1 - 0.0014 18.9 0.0 0.0057 16.9 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain Penicillinase_R PF03965.11 AIF84371.1 - 0.0067 16.5 0.0 0.022 14.8 0.0 1.9 2 0 0 2 2 2 1 Penicillinase repressor HTH_9 PF08221.6 AIF84371.1 - 0.019 14.8 0.0 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain MarR_2 PF12802.2 AIF84371.1 - 0.02 14.5 0.0 0.1 12.2 0.0 2.1 3 0 0 3 3 3 0 MarR family PadR PF03551.9 AIF84371.1 - 0.039 13.7 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.15 AIF84371.1 - 0.041 13.9 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HTH_36 PF13730.1 AIF84371.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.1 AIF84371.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Radical_SAM PF04055.16 AIF84372.1 - 1.8e-17 64.0 0.1 1.8e-17 64.0 0.0 2.7 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.1 AIF84372.1 - 2.9e-09 37.1 0.0 9.1e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 AIF84372.1 - 2.4e-08 34.0 0.0 2.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain HTH_45 PF14947.1 AIF84373.1 - 0.00095 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 AIF84373.1 - 0.0038 16.8 0.0 0.0088 15.7 0.0 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AIF84373.1 - 0.0076 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 AIF84373.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.15 AIF84373.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_27 PF13463.1 AIF84373.1 - 0.052 13.8 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_29 PF13551.1 AIF84373.1 - 0.096 12.8 0.0 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_45 PF14947.1 AIF84374.1 - 1.6e-17 63.1 0.0 1.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix bPH_5 PF10882.3 AIF84376.1 - 1.5e-06 27.9 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain Peptidase_M3 PF01432.15 AIF84377.1 - 8.6e-05 21.7 1.1 0.00089 18.3 0.7 2.3 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.10 AIF84377.1 - 0.00097 17.8 0.0 0.017 13.7 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase Taq (M32) metallopeptidase Proteasome PF00227.21 AIF84378.1 - 1e-54 184.7 1.3 1.2e-54 184.5 0.9 1.0 1 0 0 1 1 1 1 Proteasome subunit Aconitase PF00330.15 AIF84379.1 - 3.6e-171 569.7 0.0 4e-171 569.5 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AIF84380.1 - 4.1e-39 133.6 0.0 5.6e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 AIF84380.1 - 0.0047 16.3 0.0 0.21 10.9 0.0 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Pribosyltran PF00156.22 AIF84381.1 - 0.0048 16.6 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 AIF84381.1 - 0.12 12.0 0.4 0.4 10.4 0.0 2.0 3 0 0 3 3 3 0 Glutamine amidotransferase domain NT5C PF06941.7 AIF84383.1 - 3.3e-13 49.5 0.1 3.7e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase PF00702.21 AIF84383.1 - 0.0063 16.9 0.1 0.018 15.4 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LNS2 PF08235.8 AIF84383.1 - 0.066 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) HAD_2 PF13419.1 AIF84383.1 - 0.085 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3227 PF11537.3 AIF84384.1 - 0.0049 16.9 0.0 0.0059 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3227) Response_reg PF00072.19 AIF84386.1 - 7.5e-24 83.8 0.4 8.4e-24 83.7 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AIF84387.1 - 4.8e-23 80.9 0.4 2.1e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF84387.1 - 9.3e-11 41.5 1.9 2e-10 40.5 0.7 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AIF84387.1 - 0.0028 17.3 0.3 0.0087 15.7 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CHY PF05495.7 AIF84388.1 - 0.006 16.7 1.3 0.0066 16.5 0.9 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-UBR PF02207.15 AIF84388.1 - 0.0084 15.8 0.8 0.0097 15.6 0.6 1.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Cytochrome_C7 PF14522.1 AIF84388.1 - 0.014 14.9 0.9 0.016 14.7 0.6 1.2 1 0 0 1 1 1 0 Cytochrome c7 TF_Zn_Ribbon PF08271.7 AIF84388.1 - 0.025 13.9 1.3 0.038 13.3 0.9 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.2 AIF84388.1 - 0.04 13.7 0.9 0.066 13.0 0.6 1.4 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 AIF84388.1 - 0.047 13.1 3.3 0.39 10.2 0.3 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain GATA PF00320.22 AIF84388.1 - 0.055 12.8 0.2 0.093 12.0 0.1 1.4 1 1 0 1 1 1 0 GATA zinc finger Paired_CXXCH_1 PF09699.5 AIF84388.1 - 0.11 12.0 0.4 0.11 12.0 0.3 2.0 1 1 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF2082 PF09855.4 AIF84388.1 - 0.2 11.5 3.1 3.6 7.5 0.2 2.1 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_4 PF13717.1 AIF84388.1 - 0.28 10.8 2.7 0.92 9.2 1.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Cytochrom_NNT PF03264.9 AIF84388.1 - 0.31 10.4 4.2 0.74 9.2 2.9 1.7 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DNA_RNApol_7kD PF03604.8 AIF84388.1 - 0.33 10.4 3.0 2.8 7.4 2.1 2.0 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Lar_restr_allev PF14354.1 AIF84388.1 - 0.35 11.1 2.0 0.7 10.2 1.4 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_5 PF13719.1 AIF84388.1 - 0.38 10.3 3.1 1.2 8.8 2.1 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-trcl PF13451.1 AIF84388.1 - 0.43 10.2 2.5 0.78 9.4 0.2 2.0 2 0 0 2 2 2 0 Probable zinc-binding domain TFIIS_C PF01096.13 AIF84388.1 - 0.56 9.8 2.6 9.2 5.9 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2387 PF09526.5 AIF84388.1 - 0.6 10.0 3.7 15 5.5 2.9 2.0 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 AIF84388.1 - 0.61 9.9 2.4 14 5.5 0.1 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF192 PF02643.10 AIF84389.1 - 4.3e-19 68.1 0.0 5.4e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Arch_flagellin PF01917.11 AIF84390.1 - 2.9e-18 66.1 9.2 3.8e-18 65.7 6.4 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin Sigma_reg_N PF13800.1 AIF84390.1 - 0.1 12.6 0.4 0.25 11.3 0.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Regulator_TrmB PF11495.3 AIF84391.1 - 2.6e-12 46.2 0.1 3.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB TrmB PF01978.14 AIF84391.1 - 1.2e-11 44.1 0.0 3.4e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AIF84391.1 - 0.0015 18.1 0.3 0.0048 16.5 0.2 1.9 1 0 0 1 1 1 1 MarR family PLDc_2 PF13091.1 AIF84391.1 - 0.0034 17.1 0.1 0.037 13.7 0.0 2.5 2 1 0 2 2 2 1 PLD-like domain MarR PF01047.17 AIF84391.1 - 0.0055 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.5 AIF84391.1 - 0.011 15.3 0.1 0.029 13.9 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_7 PF02796.10 AIF84391.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase LytR_C PF13399.1 AIF84391.1 - 1.2 9.5 4.0 1.2 9.5 0.2 2.8 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator MCPsignal PF00015.16 AIF84392.1 - 6.5e-53 179.4 57.5 8.2e-49 166.0 26.2 3.3 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.20 AIF84392.1 - 4e-15 55.7 7.7 4.6e-14 52.3 0.0 4.5 4 1 0 4 4 4 1 HAMP domain Hormone_1 PF00103.15 AIF84392.1 - 1.8 7.8 11.0 0.43 9.8 0.2 3.2 2 1 0 3 3 3 0 Somatotropin hormone family Syntaxin PF00804.20 AIF84392.1 - 8.9 6.5 34.3 0.061 13.4 4.3 4.5 2 1 3 5 5 5 0 Syntaxin MCPsignal PF00015.16 AIF84395.1 - 8.1e-14 51.6 2.9 1.3e-13 50.9 2.0 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Cache_1 PF02743.13 AIF84395.1 - 0.0069 15.9 0.0 0.037 13.5 0.0 2.2 2 1 0 2 2 2 1 Cache domain CheW PF01584.14 AIF84397.1 - 1.8e-31 108.4 1.3 1.9e-31 108.3 0.9 1.0 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.19 AIF84398.1 - 3.1e-30 104.4 1.7 3.4e-30 104.3 1.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain OpuAC PF04069.7 AIF84398.1 - 0.087 12.1 0.1 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system CheB_methylest PF01339.12 AIF84399.1 - 1.9e-61 206.6 0.7 5e-61 205.3 0.3 1.8 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.19 AIF84399.1 - 4.6e-20 71.6 0.1 1e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF3798 PF12683.2 AIF84399.1 - 0.00032 19.8 0.0 0.0006 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3798) Hpt PF01627.18 AIF84400.1 - 5.6e-22 77.5 0.5 1.5e-21 76.2 0.4 1.7 1 0 0 1 1 1 1 Hpt domain CheW PF01584.14 AIF84400.1 - 1.9e-21 75.9 0.3 3.5e-21 75.1 0.2 1.5 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.21 AIF84400.1 - 3.3e-21 75.0 3.4 5.8e-21 74.2 0.9 2.4 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.9 AIF84400.1 - 1.9e-12 47.3 3.6 2e-12 47.2 0.9 2.4 2 0 0 2 2 2 1 Signal transducing histidine kinase, homodimeric domain Snf7 PF03357.16 AIF84400.1 - 1.6e-05 24.4 1.8 5.5e-05 22.6 1.3 2.0 1 0 0 1 1 1 1 Snf7 HATPase_c_3 PF13589.1 AIF84400.1 - 0.0035 16.9 0.1 0.0099 15.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ToxN_toxin PF13958.1 AIF84400.1 - 0.0073 15.9 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Toxin ToxN, type III toxin-antitoxin system Hus1 PF04005.7 AIF84400.1 - 0.026 13.4 0.5 1.1 8.0 0.0 2.5 3 0 0 3 3 3 0 Hus1-like protein Antitoxin-MazE PF04014.13 AIF84400.1 - 0.19 11.5 1.1 0.39 10.4 0.1 2.0 2 0 0 2 2 2 0 Antidote-toxin recognition MazE CheC PF04509.7 AIF84401.1 - 2.6e-09 36.6 0.1 8e-09 35.0 0.1 1.9 1 0 0 1 1 1 1 CheC-like family CheX PF13690.1 AIF84401.1 - 0.00086 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX Chlorosome_CsmC PF11098.3 AIF84401.1 - 0.1 12.3 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C CheD PF03975.8 AIF84402.1 - 2.9e-27 94.6 0.1 3.5e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Cu-oxidase_4 PF02578.10 AIF84402.1 - 0.077 12.0 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase CheR PF01739.13 AIF84403.1 - 4.7e-57 192.4 0.0 5.7e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.10 AIF84403.1 - 1.1e-10 40.6 0.8 2.4e-10 39.6 0.6 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.7 AIF84403.1 - 3.9e-06 27.2 0.1 2.3e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84403.1 - 6.3e-06 25.8 0.1 0.042 13.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84403.1 - 9.9e-06 26.1 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF84403.1 - 6.3e-05 23.3 0.0 0.00082 19.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84403.1 - 0.00038 20.7 0.0 0.00089 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AIF84403.1 - 0.0053 15.9 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase T2SE PF00437.15 AIF84404.1 - 3.4e-44 150.7 0.0 4.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 AIF84404.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrmB PF01978.14 AIF84405.1 - 5.2e-13 48.4 0.3 1.7e-12 46.8 0.1 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AIF84405.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF84405.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.5 AIF84405.1 - 0.14 11.8 0.8 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Arch_flagellin PF01917.11 AIF84406.1 - 6.2e-22 78.1 10.6 9.6e-22 77.5 7.3 1.3 1 1 0 1 1 1 1 Archaebacterial flagellin DUF2523 PF10734.4 AIF84406.1 - 0.62 10.3 4.8 0.51 10.5 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) Arch_flagellin PF01917.11 AIF84407.1 - 2.1e-19 69.8 18.1 3.7e-19 69.0 12.6 1.4 1 1 0 1 1 1 1 Archaebacterial flagellin DUF2393 PF09624.5 AIF84407.1 - 0.041 13.3 0.8 0.071 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Arch_flagellin PF01917.11 AIF84409.1 - 2e-08 34.0 9.3 3.5e-07 30.0 6.5 2.0 1 1 0 1 1 1 1 Archaebacterial flagellin fn3 PF00041.16 AIF84409.1 - 0.055 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain DUF973 PF06157.6 AIF84409.1 - 0.063 12.2 0.9 0.32 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF973) KaiC PF06745.8 AIF84411.1 - 1.8e-21 76.3 0.1 2e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AIF84411.1 - 1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.6 AIF84411.1 - 0.00032 19.7 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 DUF835 PF05763.7 AIF84411.1 - 0.0006 19.3 0.2 0.0014 18.1 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF835) Arch_ATPase PF01637.13 AIF84411.1 - 0.00084 19.1 0.2 0.0017 18.0 0.2 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 AIF84411.1 - 0.0024 17.9 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RAP1 PF07218.6 AIF84411.1 - 0.0073 14.4 0.1 0.0099 14.0 0.0 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) PAXNEB PF05625.6 AIF84411.1 - 0.0076 15.1 0.5 0.023 13.5 0.0 1.8 2 0 0 2 2 2 1 PAXNEB protein NACHT PF05729.7 AIF84411.1 - 0.0088 15.7 0.2 0.022 14.4 0.1 1.6 2 0 0 2 2 2 1 NACHT domain DUF2348 PF09807.4 AIF84411.1 - 0.012 14.7 2.1 0.21 10.6 0.3 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2348) AAA_14 PF13173.1 AIF84411.1 - 0.017 15.0 0.2 0.039 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIF84411.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 AIF84411.1 - 0.018 15.3 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AIF84411.1 - 0.018 15.5 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DUF815 PF05673.8 AIF84411.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GvpD PF07088.6 AIF84411.1 - 0.02 13.2 0.0 0.024 12.9 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein Ras PF00071.17 AIF84411.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Ras family DUF2075 PF09848.4 AIF84411.1 - 0.055 12.4 0.1 0.078 11.9 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 AIF84411.1 - 0.061 13.5 0.1 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.1 AIF84411.1 - 0.069 12.7 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AIF84411.1 - 0.089 12.2 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein UPF0079 PF02367.12 AIF84411.1 - 0.1 12.2 0.1 0.3 10.7 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 AIF84411.1 - 0.13 12.3 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain T2SF PF00482.18 AIF84412.1 - 9.2e-08 32.0 11.1 5.1e-06 26.4 0.3 3.3 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F DUF3227 PF11537.3 AIF84413.1 - 0.0013 18.7 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3227) RRM_1 PF00076.17 AIF84413.1 - 0.028 14.0 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRY PF13765.1 AIF84413.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 SPRY-associated domain KaiC PF06745.8 AIF84415.1 - 3.9e-53 179.9 0.4 5.9e-53 179.3 0.3 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AIF84415.1 - 2.8e-11 43.1 0.0 4.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AIF84415.1 - 1.1e-05 24.6 0.0 1.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_14 PF13173.1 AIF84415.1 - 2.7e-05 24.0 0.2 0.00016 21.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AIF84415.1 - 3e-05 23.5 0.1 0.00026 20.4 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.4 AIF84415.1 - 0.00017 20.6 0.0 0.00022 20.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 AIF84415.1 - 0.00058 18.8 0.0 0.0013 17.6 0.0 1.5 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_19 PF13245.1 AIF84415.1 - 0.0022 17.7 0.0 0.0062 16.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain GvpD PF07088.6 AIF84415.1 - 0.0027 16.0 1.0 0.015 13.6 0.7 1.9 1 1 0 1 1 1 1 GvpD gas vesicle protein PhoH PF02562.11 AIF84415.1 - 0.003 16.8 0.7 0.021 14.0 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 AIF84415.1 - 0.0037 17.3 0.1 0.0074 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 AIF84415.1 - 0.0044 15.9 0.2 0.017 13.9 0.1 1.8 1 1 1 2 2 2 1 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 AIF84415.1 - 0.005 16.5 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Rad51 PF08423.6 AIF84415.1 - 0.0095 14.8 0.1 0.022 13.6 0.1 1.7 2 1 0 2 2 2 1 Rad51 TIP49 PF06068.8 AIF84415.1 - 0.015 14.0 0.1 0.034 12.8 0.1 1.5 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 AIF84415.1 - 0.018 14.6 0.0 0.042 13.5 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 AIF84415.1 - 0.019 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 AIF84415.1 - 0.038 13.4 0.1 0.065 12.7 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase Elong_Iki1 PF10483.4 AIF84415.1 - 0.04 13.2 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 PAXNEB PF05625.6 AIF84415.1 - 0.042 12.6 0.8 0.46 9.2 0.1 2.0 1 1 1 2 2 2 0 PAXNEB protein AAA_16 PF13191.1 AIF84415.1 - 0.047 13.6 0.2 0.064 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 AIF84415.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 AIF84415.1 - 0.1 12.0 0.1 0.14 11.5 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 AIF84415.1 - 0.13 13.1 0.5 0.28 12.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 AIF84415.1 - 0.39 9.6 2.5 2.2 7.1 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase PalH PF08733.5 AIF84416.1 - 0.03 13.1 6.5 0.046 12.5 4.5 1.3 1 0 0 1 1 1 0 PalH/RIM21 DUF1686 PF07937.6 AIF84416.1 - 0.074 12.6 1.9 0.37 10.4 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1686) DUF872 PF05915.7 AIF84416.1 - 7.1 6.5 9.7 1.4 8.8 0.3 3.2 3 2 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.1 AIF84417.1 - 0.039 13.3 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Neurensin SoxE PF06525.6 AIF84417.1 - 0.05 12.8 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) TrmB PF01978.14 AIF84418.1 - 1.9e-13 49.8 0.1 1e-12 47.5 0.1 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AIF84418.1 - 0.0032 16.4 0.5 0.018 14.0 0.1 1.9 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB Arc_PepC_II PF06847.6 AIF84420.1 - 1e-06 29.0 0.4 2.4e-06 27.8 0.2 1.7 1 1 0 1 1 1 1 Archaeal Peptidase A24 C-terminus Type II Peptidase_A24 PF01478.13 AIF84420.1 - 3.1e-05 24.0 9.5 3.1e-05 24.0 6.6 2.2 2 1 0 2 2 2 1 Type IV leader peptidase family Pyridox_oxidase PF01243.15 AIF84422.1 - 3.3e-17 62.2 0.0 4.4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF84422.1 - 6.8e-10 38.9 0.0 1.1e-09 38.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AMP-binding PF00501.23 AIF84423.1 - 1.2e-97 326.9 0.1 1.5e-97 326.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AIF84423.1 - 1.9e-19 70.3 2.1 4.2e-19 69.2 0.3 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MethyltransfD12 PF02086.10 AIF84424.1 - 9.5e-42 143.2 0.0 1.3e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 AIF84424.1 - 0.00028 20.8 0.5 0.00068 19.6 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain CBFD_NFYB_HMF PF00808.18 AIF84426.1 - 3.4e-15 55.8 1.0 3.7e-15 55.7 0.7 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AIF84426.1 - 8.9e-12 44.9 0.3 9.4e-12 44.8 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AIF84426.1 - 3e-06 27.2 0.0 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 AIF84426.1 - 0.00019 21.2 0.5 0.00021 21.1 0.4 1.1 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 AIF84426.1 - 0.00045 19.9 0.0 0.00051 19.7 0.0 1.0 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 AIF84426.1 - 0.00092 18.5 0.4 0.001 18.4 0.2 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 AIF84426.1 - 0.0069 16.1 0.0 0.0074 16.0 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIIB PF00382.14 AIF84426.1 - 0.015 15.0 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Transcription factor TFIIB repeat HK97-gp10_like PF04883.7 AIF84426.1 - 0.064 14.1 0.8 0.078 13.9 0.6 1.3 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Ead_Ea22 PF13935.1 AIF84426.1 - 0.12 12.7 0.5 0.12 12.6 0.3 1.1 1 0 0 1 1 1 0 Ead/Ea22-like protein TatD_DNase PF01026.16 AIF84427.1 - 6.7e-42 143.4 0.0 8e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Ribosomal_S17e PF00833.13 AIF84428.1 - 6.3e-18 64.7 0.6 6.4e-18 64.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 CGI-121 PF08617.5 AIF84429.1 - 1e-14 54.5 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 ThiS PF02597.15 AIF84429.1 - 6.1e-08 32.9 0.3 2e-07 31.3 0.0 2.0 3 0 0 3 3 3 1 ThiS family Imm31 PF15595.1 AIF84429.1 - 0.011 15.4 0.1 0.025 14.3 0.0 1.6 1 1 0 1 1 1 0 Immunity protein 31 Urm1 PF09138.6 AIF84429.1 - 0.018 15.1 0.0 0.061 13.4 0.0 2.0 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) THUMP PF02926.12 AIF84430.1 - 9.9e-16 57.9 0.5 1.2e-15 57.6 0.3 1.2 1 0 0 1 1 1 1 THUMP domain Sua5_yciO_yrdC PF01300.13 AIF84431.1 - 1.6e-46 157.8 0.0 1.8e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination Hydantoinase_A PF01968.13 AIF84432.1 - 5.6e-52 176.6 5.4 5.6e-52 176.6 3.7 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AIF84432.1 - 2.8e-24 85.5 12.2 3.4e-24 85.2 1.3 3.6 5 0 0 5 5 5 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 AIF84432.1 - 3.5e-08 32.2 4.3 2.9e-05 22.6 0.7 2.4 2 0 0 2 2 2 2 MutL protein FGGY_N PF00370.16 AIF84432.1 - 4.4e-05 22.9 1.1 0.00011 21.6 0.7 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 AIF84432.1 - 0.00013 21.3 7.6 0.00078 18.8 0.5 4.0 3 1 1 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family DUF1673 PF07895.6 AIF84433.1 - 0.01 15.3 0.3 0.015 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) FA_desaturase PF00487.19 AIF84433.1 - 1.1 8.6 3.6 0.47 9.8 1.0 1.5 1 1 0 1 1 1 0 Fatty acid desaturase Sulfate_transp PF00916.15 AIF84434.1 - 0.1 11.5 1.3 0.12 11.3 0.9 1.2 1 0 0 1 1 1 0 Sulfate transporter family DUF4519 PF15012.1 AIF84434.1 - 1.8 8.5 6.4 0.19 11.6 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4328 PF14219.1 AIF84434.1 - 5.3 6.2 8.2 0.27 10.5 0.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) DUF1462 PF07315.6 AIF84435.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) NOSIC PF08060.8 AIF84436.1 - 0.11 12.2 0.5 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 NOSIC (NUC001) domain rve_3 PF13683.1 AIF84437.1 - 0.13 11.7 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Integrase core domain zf-RING_4 PF14570.1 AIF84440.1 - 0.02 14.4 0.7 0.02 14.4 0.5 2.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF2387 PF09526.5 AIF84440.1 - 0.025 14.4 0.3 0.025 14.4 0.2 2.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Mu-like_Com PF10122.4 AIF84440.1 - 0.051 12.6 2.8 0.12 11.4 0.2 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com Elf1 PF05129.8 AIF84440.1 - 0.18 11.5 5.6 0.62 9.8 0.1 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-C3HC4_3 PF13920.1 AIF84440.1 - 0.19 11.4 14.3 6.3 6.5 6.4 3.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 AIF84440.1 - 0.59 9.8 7.2 0.26 11.0 1.5 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-HIT PF04438.11 AIF84440.1 - 1.2 8.8 13.2 7.9 6.2 0.1 4.1 4 0 0 4 4 4 0 HIT zinc finger RecR PF02132.10 AIF84440.1 - 1.6 8.2 9.1 42 3.6 0.0 4.0 4 0 0 4 4 4 0 RecR protein V4R PF02830.13 AIF84441.1 - 8.8e-13 47.8 0.8 1.4e-12 47.2 0.5 1.3 1 0 0 1 1 1 1 V4R domain HTH_AsnC-type PF13404.1 AIF84442.1 - 1.2e-07 31.1 1.0 2.9e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AIF84442.1 - 1.2e-06 27.7 0.9 1.2e-06 27.7 0.7 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 AIF84442.1 - 0.043 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 AsnC family HTH_psq PF05225.11 AIF84442.1 - 0.043 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_23 PF13384.1 AIF84442.1 - 0.067 12.8 0.3 0.26 11.0 0.0 2.1 3 0 0 3 3 3 0 Homeodomain-like domain Put_DNA-bind_N PF06971.8 AIF84442.1 - 0.09 12.5 0.1 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Mga PF05043.8 AIF84442.1 - 0.1 12.9 0.1 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Mga helix-turn-helix domain TrmB PF01978.14 AIF84442.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AIF84442.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.7 AIF84442.1 - 0.44 10.2 0.1 0.44 10.2 0.1 2.1 3 0 0 3 3 3 0 HTH domain UDPG_MGDP_dh PF00984.14 AIF84443.1 - 6.8e-19 67.8 0.1 1.2e-18 67.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.9 AIF84443.1 - 1.9e-09 37.1 0.0 4.8e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 AIF84443.1 - 0.0005 20.0 0.1 0.0014 18.6 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 AIF84443.1 - 0.0017 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_18 PF12847.2 AIF84443.1 - 0.0062 17.0 0.1 0.012 16.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 AIF84443.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AIF84443.1 - 0.018 14.7 0.2 0.064 12.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 AIF84443.1 - 0.13 12.3 0.1 0.84 9.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HTH_45 PF14947.1 AIF84444.1 - 8e-16 57.6 0.1 9e-16 57.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix Mrr_N PF14338.1 AIF84444.1 - 0.016 15.2 0.2 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Mrr N-terminal domain Big_3_4 PF13754.1 AIF84445.1 - 8.2e-08 32.4 14.7 3e-06 27.4 3.9 5.1 4 1 1 5 5 5 2 Bacterial Ig-like domain (group 3) Mo-co_dimer PF03404.11 AIF84445.1 - 5.2e-06 26.1 1.7 0.015 14.9 0.2 3.0 1 1 1 2 2 2 2 Mo-co oxidoreductase dimerisation domain Gmad2 PF10648.4 AIF84445.1 - 6.1e-06 26.3 1.4 0.0077 16.3 0.4 3.1 3 0 0 3 3 3 2 Immunoglobulin-like domain of bacterial spore germination CarboxypepD_reg PF13620.1 AIF84445.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.7 3 1 0 3 3 3 0 Carboxypeptidase regulatory-like domain PKD PF00801.15 AIF84445.1 - 0.14 11.8 13.7 0.12 12.1 2.4 4.0 3 2 0 3 3 3 0 PKD domain YbbR PF07949.7 AIF84445.1 - 0.48 10.5 4.6 26 5.0 0.0 4.1 4 1 0 4 4 4 0 YbbR-like protein HTH_24 PF13412.1 AIF84446.1 - 2e-06 27.0 0.5 3.8e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF84446.1 - 0.0005 19.5 0.2 0.001 18.5 0.2 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AIF84446.1 - 0.0018 17.8 0.2 0.0042 16.7 0.1 1.6 1 0 0 1 1 1 1 HTH domain AsnC_trans_reg PF01037.16 AIF84446.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AsnC family HTH_20 PF12840.2 AIF84446.1 - 0.0083 15.9 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AIF84446.1 - 0.033 13.8 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.1 AIF84446.1 - 0.037 13.6 0.0 0.091 12.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.11 AIF84446.1 - 0.12 11.9 0.2 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_IclR PF09339.5 AIF84446.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.1 AIF84447.1 - 1e-06 27.9 2.2 5e-06 25.8 0.1 2.6 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF84447.1 - 0.00041 19.8 0.2 0.0029 17.0 0.1 2.2 2 1 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AIF84447.1 - 0.0012 18.4 0.2 0.0034 16.9 0.1 1.8 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.2 AIF84447.1 - 0.0017 18.1 0.6 0.0077 16.0 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain ACT_4 PF13291.1 AIF84447.1 - 0.017 15.4 0.7 0.067 13.5 0.0 2.3 3 1 0 3 3 3 0 ACT domain TrmB PF01978.14 AIF84447.1 - 0.021 14.5 0.1 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.1 AIF84447.1 - 0.034 13.8 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_IclR PF09339.5 AIF84447.1 - 0.053 13.1 0.5 0.23 11.0 0.1 2.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain Peptidase_M50 PF02163.17 AIF84448.1 - 0.052 12.4 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 RskA PF10099.4 AIF84448.1 - 0.13 12.0 0.7 0.21 11.2 0.5 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Syndecan PF01034.15 AIF84448.1 - 0.29 10.8 1.4 0.55 9.9 0.9 1.5 1 0 0 1 1 1 0 Syndecan domain SIS PF01380.17 AIF84449.1 - 3.1e-51 172.4 3.1 3e-30 104.4 1.7 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 AIF84449.1 - 2.9e-24 85.5 0.0 6.2e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AIF84449.1 - 6.4e-19 67.8 0.1 7.2e-15 54.5 0.0 2.7 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 AIF84449.1 - 5.1e-18 65.0 0.0 1.3e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.1 AIF84449.1 - 4.8e-05 23.0 4.2 0.00032 20.4 0.3 2.9 1 1 1 2 2 2 1 SIS domain GATase_4 PF13230.1 AIF84449.1 - 7.7e-05 21.4 0.1 0.00017 20.3 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Sprouty PF05210.8 AIF84450.1 - 0.028 14.4 0.4 0.028 14.4 0.3 1.0 1 0 0 1 1 1 0 Sprouty protein (Spry) Sina PF03145.11 AIF84450.1 - 0.18 11.4 0.9 0.17 11.5 0.6 1.1 1 0 0 1 1 1 0 Seven in absentia protein family F5_F8_type_C PF00754.20 AIF84452.1 - 7.3e-16 58.1 2.6 7.3e-16 58.1 1.8 2.2 2 0 0 2 2 2 1 F5/8 type C domain Big_3_4 PF13754.1 AIF84452.1 - 2.8e-05 24.3 1.1 2.8e-05 24.3 0.8 3.1 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) Mo-co_dimer PF03404.11 AIF84452.1 - 0.00045 19.8 0.8 0.0015 18.1 0.5 1.8 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Sad1_UNC PF07738.8 AIF84452.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Beta_helix PF13229.1 AIF84453.1 - 1.3e-17 63.9 42.3 4.7e-11 42.6 10.7 2.8 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.8 AIF84453.1 - 9.9e-17 60.8 21.4 9.9e-17 60.8 14.8 2.1 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 AIF84453.1 - 0.0037 16.4 17.0 0.011 14.9 10.2 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF1565) Polysacc_deac_1 PF01522.16 AIF84453.1 - 0.053 13.1 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide deacetylase Glycos_transf_2 PF00535.21 AIF84454.1 - 5.7e-32 110.7 0.1 2e-31 108.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIF84454.1 - 1.2e-25 90.7 0.2 4e-25 88.9 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 AIF84454.1 - 5.7e-17 61.3 0.2 1.6e-15 56.5 0.1 2.1 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 AIF84454.1 - 4.1e-12 46.2 3.6 4.1e-12 46.2 2.5 2.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 AIF84454.1 - 6.4e-09 35.3 1.7 4.1e-07 29.4 0.0 2.4 3 0 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF84454.1 - 2.1e-05 23.7 0.1 3.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MARVEL PF01284.18 AIF84454.1 - 0.053 13.3 5.5 0.59 9.9 0.0 2.4 2 0 0 2 2 2 0 Membrane-associating domain Diphthamide_syn PF01866.12 AIF84454.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Glyco_tran_WecB PF03808.8 AIF84454.1 - 0.11 11.9 0.0 8.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family YjgF_endoribonc PF14588.1 AIF84455.1 - 2.4e-42 144.3 0.0 2.7e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 AIF84455.1 - 2.9e-22 78.6 0.1 4.2e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DHHA1 PF02272.14 AIF84456.1 - 1e-12 47.5 0.2 2.8e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.15 AIF84456.1 - 0.00012 21.7 0.1 0.00019 21.1 0.1 1.5 1 0 0 1 1 1 1 DHH family Thioredox_DsbH PF03190.10 AIF84457.1 - 1e-75 252.9 0.0 1.6e-75 252.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 AIF84457.1 - 1.1e-12 47.7 0.0 2.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.8 AIF84457.1 - 1.8e-12 46.9 0.2 2.6e-05 23.4 0.0 2.9 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 AIF84457.1 - 1.6e-07 31.0 0.1 2.9e-06 26.9 0.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 AIF84457.1 - 3.2e-07 29.8 1.4 0.02 14.1 0.0 4.1 4 1 0 4 4 4 2 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.6 AIF84457.1 - 2.2e-05 23.6 0.7 0.018 14.0 0.1 2.6 2 1 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Thioredoxin_2 PF13098.1 AIF84457.1 - 0.00087 19.4 0.0 0.0035 17.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain DUF1680 PF07944.7 AIF84457.1 - 0.0038 15.5 0.0 0.17 10.1 0.0 2.7 2 1 1 3 3 3 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_47 PF01532.15 AIF84457.1 - 0.025 13.2 0.3 0.13 10.8 0.0 2.2 2 1 0 2 2 2 0 Glycosyl hydrolase family 47 PMBR PF09373.5 AIF84457.1 - 0.028 14.3 0.4 8.7 6.4 0.0 3.4 3 0 0 3 3 3 0 Pseudomurein-binding repeat KdpD PF02702.12 AIF84458.1 - 0.044 12.9 0.4 0.056 12.5 0.3 1.0 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain FixQ PF05545.6 AIF84459.1 - 0.22 11.1 1.0 2.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1664 PF07889.7 AIF84459.1 - 1.3 8.8 4.4 0.56 10.0 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pyridox_ox_2 PF12900.2 AIF84460.1 - 1.8e-25 89.4 0.0 2.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 AIF84460.1 - 3.6e-15 55.7 0.0 6.6e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.7 AIF84460.1 - 2.8e-05 23.6 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain ChaB PF06150.7 AIF84461.1 - 0.12 12.1 0.3 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 ChaB SAE2 PF08573.5 AIF84461.1 - 0.18 12.5 1.0 0.23 12.1 0.7 1.4 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus HTH_45 PF14947.1 AIF84462.1 - 1.5e-19 69.6 0.4 1.6e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF84462.1 - 0.003 17.1 0.2 0.0036 16.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) PadR PF03551.9 AIF84463.1 - 2.9e-10 39.7 0.0 1.1e-09 37.9 0.0 1.9 1 1 1 2 2 2 1 Transcriptional regulator PadR-like family HTH_45 PF14947.1 AIF84463.1 - 0.00046 19.9 0.0 0.00098 18.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix HemN_C PF06969.11 AIF84463.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 HemN C-terminal domain MEDS PF14417.1 AIF84465.1 - 0.0011 18.0 0.0 0.0023 17.0 0.0 1.6 1 1 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain KaiC PF06745.8 AIF84465.1 - 0.028 13.5 0.0 0.055 12.5 0.0 1.5 1 1 0 1 1 1 0 KaiC PAP2 PF01569.16 AIF84466.1 - 2.8e-21 75.5 3.7 2.8e-21 75.5 2.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 AIF84466.1 - 0.0003 20.3 3.2 0.00079 19.0 2.2 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 AIF84466.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.5 3 1 0 3 3 3 0 PAP2 superfamily C-terminal DUF4396 PF14342.1 AIF84467.1 - 1.4e-26 93.2 11.1 1.8e-26 92.9 7.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF1049 PF06305.6 AIF84467.1 - 3.1 7.3 6.8 3 7.3 2.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) DUF2374 PF09574.5 AIF84469.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) UPF0086 PF01868.11 AIF84470.1 - 0.00012 21.6 0.0 0.059 13.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function UPF0086 Na_H_Exchanger PF00999.16 AIF84471.1 - 6.6e-66 222.3 50.2 7.9e-66 222.1 34.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4605 PF15378.1 AIF84471.1 - 2 8.1 11.4 0.11 12.1 2.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4605) TauE PF01925.14 AIF84473.1 - 1.7e-28 99.7 17.4 1.9e-28 99.5 12.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE SpoV PF08183.6 AIF84473.1 - 0.4 10.4 3.7 1.3 8.8 2.5 1.9 1 0 0 1 1 1 0 Stage V sporulation protein family DUF3792 PF12670.2 AIF84473.1 - 1.3 8.8 9.8 0.19 11.6 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) UPF0016 PF01169.14 AIF84473.1 - 2.6 8.2 12.4 7.1 6.8 1.5 3.4 2 1 1 3 3 3 0 Uncharacterized protein family UPF0016 Glug PF07581.7 AIF84473.1 - 9.8 6.6 13.5 12 6.3 0.2 4.3 5 0 0 5 5 5 0 The GLUG motif CRCB PF02537.10 AIF84474.1 - 7.4e-23 80.6 7.8 8.9e-23 80.4 5.4 1.1 1 0 0 1 1 1 1 CrcB-like protein DUF190 PF02641.10 AIF84475.1 - 1.6e-20 72.8 0.1 1.7e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 DUF3240 PF11582.3 AIF84475.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Cation_efflux PF01545.16 AIF84476.1 - 2.2e-50 171.3 5.4 2.4e-50 171.2 3.8 1.0 1 0 0 1 1 1 1 Cation efflux family Rab5ip PF07019.7 AIF84476.1 - 0.16 12.1 0.2 0.16 12.1 0.1 3.1 2 2 1 3 3 3 0 Rab5-interacting protein (Rab5ip) DUF3040 PF11239.3 AIF84479.1 - 0.08 12.9 2.1 0.085 12.9 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) IncA PF04156.9 AIF84479.1 - 0.25 10.9 4.1 0.28 10.7 2.8 1.1 1 0 0 1 1 1 0 IncA protein DUF2619 PF10942.3 AIF84479.1 - 1.2 9.1 4.1 1.6 8.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2619) Thioredoxin_4 PF13462.1 AIF84480.1 - 1.8e-34 119.0 0.0 2.7e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AIF84480.1 - 2.7e-14 53.1 1.5 4.1e-13 49.3 0.3 2.4 2 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AIF84480.1 - 8.4e-08 32.3 0.1 5.7e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain ETRAMP PF09716.5 AIF84480.1 - 0.013 15.4 0.8 0.022 14.7 0.6 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3542 PF12061.3 AIF84481.1 - 0.0049 15.9 0.0 0.0092 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3542) CDC37_N PF03234.9 AIF84481.1 - 0.019 15.3 19.9 0.02 15.2 1.0 3.9 1 1 3 4 4 4 0 Cdc37 N terminal kinase binding Bystin PF05291.6 AIF84481.1 - 0.045 12.6 0.6 0.1 11.4 0.3 1.7 1 1 0 1 1 1 0 Bystin TPR_8 PF13181.1 AIF84481.1 - 0.052 13.3 0.3 23 5.0 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GLTSCR1 PF15249.1 AIF84481.1 - 0.056 13.5 0.8 0.056 13.5 0.5 3.3 3 1 0 3 3 3 0 Glioma tumor suppressor candidate region TMF_TATA_bd PF12325.3 AIF84481.1 - 0.18 11.5 28.1 2.9 7.6 0.5 4.4 2 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding ParB PF08775.5 AIF84481.1 - 0.19 12.0 11.4 0.73 10.1 0.1 4.8 4 1 1 5 5 5 0 ParB family FlaC_arch PF05377.6 AIF84481.1 - 0.22 11.4 5.8 3.9 7.4 0.0 4.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF677 PF05055.7 AIF84481.1 - 0.44 9.1 9.9 0.23 10.0 0.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF677) CorA PF01544.13 AIF84481.1 - 0.61 9.0 5.0 7.4 5.5 0.3 3.0 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Cob_adeno_trans PF01923.13 AIF84481.1 - 0.93 9.2 13.8 0.3 10.8 3.3 3.5 2 2 2 4 4 4 0 Cobalamin adenosyltransferase Fib_alpha PF08702.5 AIF84481.1 - 1.3 9.0 16.2 0.75 9.9 0.2 4.8 3 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 AIF84481.1 - 1.9 8.9 16.8 7.4 7.0 0.0 4.4 4 1 1 5 5 4 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 AIF84481.1 - 1.9 8.2 16.4 2.6 7.8 3.4 4.3 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus MitMem_reg PF13012.1 AIF84481.1 - 3.7 7.6 11.9 3.1 7.9 0.2 4.4 2 2 2 5 5 5 0 Maintenance of mitochondrial structure and function Reo_sigmaC PF04582.7 AIF84481.1 - 7.1 5.7 16.4 0.45 9.6 0.9 3.7 1 1 0 3 3 3 0 Reovirus sigma C capsid protein DUF2627 PF11118.3 AIF84482.1 - 0.057 13.5 1.9 0.95 9.6 1.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) GerPC PF10737.4 AIF84484.1 - 0.083 12.6 0.6 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC Cupin_2 PF07883.6 AIF84485.1 - 3.8e-11 42.3 0.0 4.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AIF84485.1 - 3.9e-07 29.5 0.0 5.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 AIF84485.1 - 0.00026 20.6 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.3 AIF84485.1 - 0.00053 19.9 0.0 0.00067 19.5 0.0 1.1 1 0 0 1 1 1 1 Mif2/CENP-C like ARD PF03079.9 AIF84485.1 - 0.0009 19.2 0.1 0.0015 18.4 0.0 1.4 1 1 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 AIF84485.1 - 0.00099 18.7 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 AIF84485.1 - 0.0061 15.9 0.0 0.013 14.9 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 AIF84485.1 - 0.039 13.5 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase BNR_2 PF13088.1 AIF84486.1 - 0.0001 21.6 6.6 0.00018 20.9 1.5 3.0 1 1 2 3 3 3 2 BNR repeat-like domain Glyco_hydro_43 PF04616.9 AIF84486.1 - 0.00012 21.3 1.2 0.0085 15.2 0.1 2.3 1 1 3 4 4 4 3 Glycosyl hydrolases family 43 DZR PF12773.2 AIF84487.1 - 0.0032 17.2 1.3 0.0037 17.0 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon Paired_CXXCH_1 PF09699.5 AIF84487.1 - 0.014 14.9 0.5 0.21 11.1 0.1 2.1 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Ribosomal_L40e PF01020.12 AIF84487.1 - 0.039 13.5 3.1 0.047 13.2 2.1 1.2 1 0 0 1 1 1 0 Ribosomal L40e family DnaJ_CXXCXGXG PF00684.14 AIF84487.1 - 0.048 13.7 1.7 0.056 13.4 1.2 1.2 1 0 0 1 1 1 0 DnaJ central domain zinc_ribbon_2 PF13240.1 AIF84487.1 - 0.072 12.5 3.9 0.11 12.0 2.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AIF84487.1 - 0.073 12.5 3.4 0.13 11.8 2.4 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 AIF84487.1 - 0.16 11.2 2.7 0.21 10.8 1.9 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Fer4_4 PF12800.2 AIF84487.1 - 0.25 11.7 1.9 15 6.2 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Cytochrome_C7 PF14522.1 AIF84487.1 - 0.34 10.5 3.8 0.57 9.8 2.5 1.6 1 1 0 1 1 1 0 Cytochrome c7 DUF1752 PF08550.5 AIF84487.1 - 0.46 10.1 2.7 8.2 6.1 0.1 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) Zn_Tnp_IS1595 PF12760.2 AIF84487.1 - 2.2 8.1 6.2 8.8 6.2 4.3 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain HTH_45 PF14947.1 AIF84489.1 - 1.3e-17 63.3 0.4 2.4e-17 62.5 0.3 1.4 1 1 0 1 1 1 1 Winged helix-turn-helix FaeA PF04703.7 AIF84489.1 - 0.077 13.1 0.3 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 FaeA-like protein DUF4199 PF13858.1 AIF84490.1 - 0.077 12.9 0.2 0.079 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PsaL PF02605.10 AIF84490.1 - 0.11 12.0 0.3 0.12 11.9 0.2 1.0 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI DUF2837 PF10997.3 AIF84490.1 - 0.14 11.3 1.1 0.15 11.1 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2837) DUF2613 PF11021.3 AIF84490.1 - 0.19 11.4 3.6 0.18 11.5 2.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) Adeno_E3_CR2 PF02439.10 AIF84490.1 - 1.3 8.6 4.8 2.3 7.8 3.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PT-VENN PF04829.8 AIF84490.1 - 2.9 7.5 4.8 1.3 8.6 1.8 1.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif SKG6 PF08693.5 AIF84490.1 - 5.8 6.3 6.4 12 5.3 4.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain rve PF00665.21 AIF84492.1 - 6.2e-19 68.2 0.1 9.5e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 AIF84492.1 - 6.2e-08 32.0 0.5 6.2e-08 32.0 0.3 3.1 2 2 0 2 2 2 1 Integrase core domain HTH_29 PF13551.1 AIF84492.1 - 0.00027 21.0 0.4 0.00061 19.9 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 AIF84492.1 - 0.0024 17.8 1.4 0.0024 17.8 1.0 2.3 3 0 0 3 3 3 1 HTH-like domain HTH_23 PF13384.1 AIF84492.1 - 0.0058 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 AIF84492.1 - 0.014 14.8 0.2 0.026 13.9 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 rve_2 PF13333.1 AIF84492.1 - 0.014 15.4 5.1 0.4 10.7 0.1 3.1 3 0 0 3 3 3 0 Integrase core domain HTH_28 PF13518.1 AIF84492.1 - 0.018 15.0 0.1 0.061 13.3 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1792 PF08759.6 AIF84492.1 - 0.034 13.7 0.5 0.06 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) HTH_33 PF13592.1 AIF84492.1 - 0.16 11.5 2.9 1 8.9 0.3 2.5 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_1 PF01609.16 AIF84493.1 - 2e-06 27.5 1.3 3.4e-06 26.7 0.9 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_5 PF13737.1 AIF84493.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Hydrolase_3 PF08282.7 AIF84494.1 - 6.2e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 AIF84494.1 - 0.021 13.7 0.0 0.83 8.5 0.0 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase S6PP PF05116.8 AIF84494.1 - 0.064 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase TFIIB PF00382.14 AIF84495.1 - 5e-31 106.3 5.7 3.5e-17 61.9 0.4 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AIF84495.1 - 6.6e-08 31.7 0.8 1.1e-07 30.9 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AIF84495.1 - 0.00052 19.5 0.1 0.078 12.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.11 AIF84495.1 - 0.00072 18.8 0.1 0.03 13.6 0.0 2.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.7 AIF84495.1 - 0.0009 18.8 0.3 0.0058 16.2 0.0 2.5 4 0 0 4 4 4 1 HTH domain HTH_Crp_2 PF13545.1 AIF84495.1 - 0.0015 18.2 0.1 5 6.9 0.0 3.4 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.7 AIF84495.1 - 0.0027 17.1 0.1 0.0069 15.8 0.0 1.7 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 AIF84495.1 - 0.0061 16.6 0.1 0.44 10.6 0.0 2.5 2 0 0 2 2 2 1 Transcriptional regulator LacI PF00356.16 AIF84495.1 - 0.017 14.7 2.8 0.78 9.4 0.1 3.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.1 AIF84495.1 - 0.024 14.2 0.4 0.19 11.4 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain TrmB PF01978.14 AIF84495.1 - 0.037 13.7 1.6 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Chordopox_RPO7 PF05864.7 AIF84495.1 - 7.4 6.7 6.0 1.6 8.8 0.2 2.8 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PEPCK_ATP PF01293.15 AIF84497.1 - 3e-213 708.5 0.0 3.4e-213 708.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.1 AIF84497.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AIF84497.1 - 0.096 12.2 0.0 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 AIF84497.1 - 0.13 10.7 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIF84497.1 - 0.16 11.5 0.5 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 AIF84497.1 - 0.18 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain PALP PF00291.20 AIF84498.1 - 4.4e-56 190.3 0.0 5.6e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.10 AIF84498.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RNA_pol_Rpc34 PF05158.7 AIF84499.1 - 0.0021 17.2 0.1 0.0075 15.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpc34 subunit eIF3g PF12353.3 AIF84499.1 - 0.0064 16.4 0.1 0.0088 15.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G TrmB PF01978.14 AIF84499.1 - 0.0082 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.6 AIF84499.1 - 0.012 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Rrf2 PF02082.15 AIF84499.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator NAM PF02365.10 AIF84499.1 - 0.074 13.2 0.4 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 No apical meristem (NAM) protein HTH_20 PF12840.2 AIF84499.1 - 0.078 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain B-block_TFIIIC PF04182.7 AIF84499.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Oxidored_q1 PF00361.15 AIF84500.1 - 2.9e-53 180.8 21.6 2.9e-53 180.8 15.0 2.9 2 0 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 AIF84500.1 - 4.1e-06 26.2 3.2 9.9e-06 25.0 1.3 2.5 1 1 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADHdh PF00146.16 AIF84501.1 - 2.4e-19 69.5 14.3 3.1e-19 69.1 9.9 1.1 1 0 0 1 1 1 1 NADH dehydrogenase Oxidored_q2 PF00420.19 AIF84502.1 - 2.3e-05 23.8 8.4 2.3e-05 23.8 5.9 2.6 2 1 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MitoNEET_N PF10660.4 AIF84502.1 - 2.8 7.8 5.8 2.5 7.9 1.1 2.4 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Oxidored_q1 PF00361.15 AIF84503.1 - 1.7e-53 181.6 26.1 1.7e-53 181.6 18.1 3.1 3 1 1 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 AIF84503.1 - 3.9 7.1 9.1 0.47 10.0 0.1 3.5 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Complex1_49kDa PF00346.14 AIF84504.1 - 1.1e-21 77.0 0.9 8.3e-18 64.3 0.8 2.9 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Complex1_30kDa PF00329.14 AIF84504.1 - 3.7e-20 72.0 0.0 9.3e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF1845 PF08900.6 AIF84504.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Oxidored_q6 PF01058.17 AIF84505.1 - 1e-30 105.9 1.1 2.8e-30 104.6 0.2 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Fer4_7 PF12838.2 AIF84505.1 - 0.0011 19.3 2.8 0.0069 16.7 1.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 AIF84505.1 - 0.0071 16.8 3.8 0.017 15.7 0.0 3.0 3 1 0 3 3 3 1 4Fe-4S single cluster domain Fer4_10 PF13237.1 AIF84505.1 - 0.018 14.8 0.3 0.083 12.7 0.1 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF84505.1 - 0.037 14.0 1.2 0.085 12.8 0.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.22 AIF84505.1 - 0.039 13.5 4.8 0.18 11.4 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 AIF84505.1 - 0.04 13.8 3.2 1.3 9.0 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain FpoO PF10621.4 AIF84505.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Fer4_13 PF13370.1 AIF84505.1 - 0.15 12.4 0.0 0.15 12.4 0.0 2.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF3368 PF11848.3 AIF84506.1 - 0.11 12.0 0.3 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) UBA PF00627.26 AIF84507.1 - 0.0044 16.8 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 UBA/TS-N domain CARD PF00619.16 AIF84507.1 - 0.031 14.1 0.4 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Caspase recruitment domain AdoHcyase PF05221.12 AIF84508.1 - 2.2e-65 220.2 0.1 2.5e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AIF84508.1 - 2.7e-56 189.8 2.6 3.7e-55 186.1 1.5 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AIF84508.1 - 7.7e-11 41.4 1.0 1.6e-10 40.4 0.2 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AIF84508.1 - 3.7e-07 29.6 0.3 8.9e-07 28.4 0.2 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 AIF84508.1 - 0.0013 18.8 1.0 0.015 15.3 0.2 2.3 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 AIF84508.1 - 0.0015 18.1 0.6 0.0028 17.2 0.4 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 AIF84508.1 - 0.0084 16.0 0.1 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 AIF84508.1 - 0.045 13.3 3.4 0.051 13.1 0.8 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 AIF84508.1 - 0.066 13.6 0.3 0.18 12.2 0.2 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 AIF84508.1 - 0.24 11.6 1.2 0.58 10.4 0.6 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Pribosyltran PF00156.22 AIF84509.1 - 6.2e-24 84.1 1.4 9.2e-24 83.5 1.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AIF84509.1 - 2.9e-06 26.6 0.1 4.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 AIF84509.1 - 0.00017 20.9 0.1 0.0018 17.6 0.0 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase Lysine_decarbox PF03641.9 AIF84510.1 - 4.9e-06 26.3 0.0 4.9e-06 26.3 0.0 2.4 2 1 1 3 3 3 1 Possible lysine decarboxylase DNA_processg_A PF02481.10 AIF84510.1 - 8.9e-05 21.4 0.7 0.0012 17.8 0.4 2.0 2 0 0 2 2 2 1 DNA recombination-mediator protein A 3HCDH_N PF02737.13 AIF84511.1 - 5.5e-65 218.3 0.0 1.4e-64 217.0 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AIF84511.1 - 2.3e-32 111.2 0.3 3.9e-25 88.0 0.0 3.2 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 AIF84511.1 - 6.3e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 AIF84511.1 - 5.3e-05 23.1 0.1 9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AIF84511.1 - 0.0091 16.4 0.2 0.044 14.2 0.2 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 AIF84511.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_L39 PF00832.15 AIF84512.1 - 6.6e-19 67.0 14.0 8.3e-19 66.7 9.7 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_L31e PF01198.14 AIF84513.1 - 5.8e-26 89.9 1.7 8e-26 89.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_60s PF00428.14 AIF84513.1 - 0.023 15.0 8.4 0.036 14.4 5.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Etmic-2 PF06670.6 AIF84513.1 - 0.053 12.2 0.5 0.056 12.1 0.3 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 NUMOD3 PF07460.6 AIF84514.1 - 0.12 12.3 2.1 0.16 11.8 1.5 1.1 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) DnaJ_CXXCXGXG PF00684.14 AIF84515.1 - 0.0078 16.2 6.6 0.014 15.4 4.6 1.4 1 1 0 1 1 1 1 DnaJ central domain DUF2175 PF09943.4 AIF84515.1 - 0.034 14.2 0.8 0.034 14.2 0.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF983 PF06170.7 AIF84515.1 - 0.041 13.9 0.3 0.041 13.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF983) zf-trcl PF13451.1 AIF84515.1 - 0.043 13.4 0.3 0.043 13.4 0.2 3.1 3 0 0 3 3 3 0 Probable zinc-binding domain zf-C2H2 PF00096.21 AIF84515.1 - 0.61 10.5 0.2 0.61 10.5 0.2 3.2 3 1 0 3 3 3 0 Zinc finger, C2H2 type HypA PF01155.14 AIF84515.1 - 8.7 6.0 8.2 8.1 6.1 4.6 1.7 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 AIF84515.1 - 8.8 5.9 14.4 1.6 8.2 4.8 3.1 2 1 0 2 2 2 0 A2L zinc ribbon domain Tubulin PF00091.20 AIF84516.1 - 1.9e-11 44.1 0.1 8.1e-10 38.8 0.0 2.1 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Radical_SAM PF04055.16 AIF84517.1 - 8.6e-24 84.5 0.0 1.4e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 AIF84517.1 - 2.9e-17 62.3 0.3 9.3e-17 60.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Tic20 PF09685.5 AIF84520.1 - 0.058 13.3 0.1 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Tic20-like protein AhpC-TSA PF00578.16 AIF84522.1 - 4.3e-24 84.5 0.0 5.5e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIF84522.1 - 1e-17 64.0 0.0 1.2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin GSHPx PF00255.14 AIF84522.1 - 6.4e-07 28.7 0.0 9.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_8 PF13905.1 AIF84522.1 - 0.0009 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AIF84522.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain SCO1-SenC PF02630.9 AIF84522.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC DAO PF01266.19 AIF84523.1 - 7.3e-08 31.6 0.5 0.0012 17.7 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AIF84523.1 - 1.4e-06 28.2 0.6 1.6e-05 24.8 0.4 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AIF84523.1 - 8.5e-05 21.1 5.7 0.00013 20.5 1.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 AIF84523.1 - 0.00012 22.1 0.2 0.00027 21.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AIF84523.1 - 0.00029 19.9 1.7 0.15 11.1 0.8 3.1 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 AIF84523.1 - 0.00046 19.3 1.1 0.00046 19.3 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AIF84523.1 - 0.00048 19.0 1.5 0.001 18.0 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 AIF84523.1 - 0.00058 19.0 0.3 0.0011 18.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 AIF84523.1 - 0.002 18.1 2.1 0.0046 16.9 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AIF84523.1 - 0.017 14.0 0.5 0.042 12.7 0.3 1.7 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 AIF84523.1 - 0.14 12.5 0.7 0.48 10.8 0.5 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 AIF84523.1 - 0.17 12.3 3.1 0.33 11.3 2.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIF84523.1 - 0.25 11.3 1.5 0.4 10.6 0.5 1.8 2 0 0 2 2 1 0 4Fe-4S binding domain NAD_binding_9 PF13454.1 AIF84523.1 - 0.3 10.8 1.5 2.1 8.0 0.7 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Fer4 PF00037.22 AIF84523.1 - 0.91 9.2 4.5 0.26 10.9 0.8 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_alpha PF00766.14 AIF84524.1 - 4e-28 96.8 0.1 8.7e-28 95.7 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 AIF84524.1 - 3e-16 59.5 0.0 5.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF PF01012.16 AIF84525.1 - 2.3e-21 76.2 0.1 3.1e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HD_4 PF13328.1 AIF84526.1 - 2.5e-15 56.5 0.1 4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 HD domain MannoseP_isomer PF01050.13 AIF84527.1 - 3.8e-20 72.0 0.0 4.3e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_2 PF07883.6 AIF84527.1 - 2.1e-08 33.5 0.0 3.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 AIF84527.1 - 0.014 14.7 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CENP-C_C PF11699.3 AIF84527.1 - 0.032 14.2 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like DUF1255 PF06865.6 AIF84527.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1255) Alginate_exp PF13372.1 AIF84527.1 - 0.095 11.3 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Alginate export AraC_binding PF02311.14 AIF84527.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Mus7 PF09462.5 AIF84528.1 - 0.019 13.8 0.0 0.021 13.6 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family DUF4066 PF13278.1 AIF84528.1 - 0.074 12.3 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative amidotransferase HTH_20 PF12840.2 AIF84529.1 - 2.8e-16 59.0 0.3 6.4e-16 57.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.15 AIF84529.1 - 6.9e-13 48.0 0.0 1.8e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AIF84529.1 - 3.7e-12 45.4 0.0 8.4e-12 44.2 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AIF84529.1 - 2e-08 33.7 0.0 5.4e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 AIF84529.1 - 6.2e-06 26.1 0.1 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_11 PF08279.7 AIF84529.1 - 2.6e-05 23.7 0.1 7.1e-05 22.3 0.0 1.7 2 0 0 2 2 1 1 HTH domain HTH_27 PF13463.1 AIF84529.1 - 9.5e-05 22.6 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.1 AIF84529.1 - 0.00025 20.7 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain B-block_TFIIIC PF04182.7 AIF84529.1 - 0.0013 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_12 PF08461.5 AIF84529.1 - 0.0038 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain MarR PF01047.17 AIF84529.1 - 0.0049 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF84529.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2513 PF10711.4 AIF84529.1 - 0.024 14.7 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_28 PF13518.1 AIF84529.1 - 0.028 14.4 0.0 0.077 13.0 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 AIF84529.1 - 0.03 13.6 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 FaeA PF04703.7 AIF84529.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein HTH_10 PF04967.7 AIF84529.1 - 0.035 13.6 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain HTH_36 PF13730.1 AIF84529.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 AIF84529.1 - 0.073 12.5 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 1 0 Sigma-70, region 4 HTH_IclR PF09339.5 AIF84529.1 - 0.088 12.4 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.1 AIF84529.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain TIM21 PF08294.6 AIF84529.1 - 0.11 12.1 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 TIM21 Rrf2 PF02082.15 AIF84529.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Asn_synthase PF00733.16 AIF84530.1 - 5.6e-52 176.7 0.1 9.4e-52 176.0 0.1 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AIF84530.1 - 2.3e-35 121.0 0.0 4.2e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AIF84530.1 - 3.1e-33 114.5 0.1 6.1e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AIF84530.1 - 4.1e-13 48.7 0.2 2e-10 39.9 0.1 3.1 1 1 1 2 2 2 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 AIF84530.1 - 0.00046 19.1 0.0 0.0029 16.5 0.0 2.1 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 AIF84530.1 - 0.004 16.4 0.0 0.0083 15.4 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 AIF84530.1 - 0.038 13.7 0.0 0.095 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF3700 PF12481.3 AIF84530.1 - 0.044 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein DUF4321 PF14209.1 AIF84530.1 - 0.18 11.4 0.0 0.65 9.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4321) HypA PF01155.14 AIF84531.1 - 0.00062 19.4 0.3 0.00067 19.3 0.2 1.0 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family C1_1 PF00130.17 AIF84531.1 - 0.0018 17.9 1.5 0.0023 17.6 1.0 1.1 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Cytochrom_c3_2 PF14537.1 AIF84531.1 - 0.0042 17.3 2.8 0.0048 17.2 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c3 Prok-RING_1 PF14446.1 AIF84531.1 - 0.005 16.5 2.3 0.0067 16.1 1.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Cytochrome_C7 PF14522.1 AIF84531.1 - 0.018 14.6 3.8 0.038 13.6 2.9 1.4 1 1 0 1 1 1 0 Cytochrome c7 Spt4 PF06093.8 AIF84531.1 - 0.03 14.2 0.9 0.031 14.1 0.6 1.1 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger zinc-ribbons_6 PF07191.7 AIF84531.1 - 0.032 14.0 0.4 0.036 13.8 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-dskA_traR PF01258.12 AIF84531.1 - 0.035 13.8 0.9 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Paired_CXXCH_1 PF09699.5 AIF84531.1 - 0.04 13.4 0.6 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DHC PF09626.5 AIF84531.1 - 0.1 13.2 1.2 6.3 7.4 0.1 2.0 2 0 0 2 2 2 0 Dihaem cytochrome c PSCyt3 PF07627.6 AIF84531.1 - 0.52 10.1 2.2 1.4 8.7 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) Fer2_BFD PF04324.10 AIF84531.1 - 0.54 10.3 2.5 5.5 7.1 1.7 2.0 1 1 0 1 1 1 0 BFD-like [2Fe-2S] binding domain YhfH PF14149.1 AIF84531.1 - 6.8 6.5 6.8 17 5.3 4.7 1.6 1 1 0 1 1 1 0 YhfH-like protein UvrB PF12344.3 AIF84532.1 - 3e-21 74.6 2.1 9.1e-21 73.1 1.5 1.9 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.26 AIF84532.1 - 3.3e-15 55.6 0.0 1.1e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIF84532.1 - 6.8e-12 45.5 0.3 4.3e-11 42.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AIF84532.1 - 2.3e-07 30.4 0.2 0.00013 21.4 0.0 3.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 AIF84532.1 - 0.00016 21.3 0.1 0.0049 16.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain UVR PF02151.14 AIF84532.1 - 0.0091 15.4 7.0 0.0091 15.4 4.8 2.8 2 0 0 2 2 2 1 UvrB/uvrC motif Kinesin PF00225.18 AIF84532.1 - 0.0092 14.7 0.1 0.017 13.8 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain UB2H PF14814.1 AIF84532.1 - 0.049 13.3 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain Tim44 PF04280.10 AIF84532.1 - 0.11 12.4 1.8 0.75 9.7 0.0 2.5 2 0 0 2 2 2 0 Tim44-like domain Ribosomal_S20p PF01649.13 AIF84532.1 - 3.3 8.1 7.4 2 8.8 2.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S20 ABC_tran PF00005.22 AIF84533.1 - 2.5e-22 79.6 0.6 0.0002 21.6 0.0 4.6 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.14 AIF84533.1 - 1.6e-10 40.5 0.7 0.27 10.4 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AIF84533.1 - 9.2e-09 35.6 10.2 0.0023 17.9 0.0 4.6 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.1 AIF84533.1 - 1.4e-08 34.0 0.2 0.0074 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AIF84533.1 - 2.6e-08 33.5 0.1 0.0017 17.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 AIF84533.1 - 4.9e-07 29.9 0.0 0.0073 16.3 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 AIF84533.1 - 6.3e-07 28.7 0.0 0.018 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 AIF84533.1 - 4.6e-06 26.5 0.0 0.055 13.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 AIF84533.1 - 1.1e-05 25.3 0.8 0.16 11.8 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 AIF84533.1 - 2.2e-05 25.2 6.1 0.089 13.6 0.4 4.2 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 AIF84533.1 - 2.5e-05 23.8 0.8 0.09 12.2 0.0 3.1 4 0 0 4 4 3 2 AAA-like domain AAA_18 PF13238.1 AIF84533.1 - 4.5e-05 23.7 0.5 0.36 11.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 AIF84533.1 - 4.6e-05 23.0 0.0 0.27 10.9 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain NACHT PF05729.7 AIF84533.1 - 7.3e-05 22.4 0.0 0.089 12.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 AIF84533.1 - 9.7e-05 22.5 4.0 0.68 10.0 0.0 4.4 5 0 0 5 5 5 2 AAA domain DnaJ_CXXCXGXG PF00684.14 AIF84533.1 - 0.00013 21.9 13.3 0.0044 17.0 0.4 4.4 3 1 1 4 4 4 1 DnaJ central domain AAA_23 PF13476.1 AIF84533.1 - 0.00014 22.2 11.7 0.00073 19.9 0.5 3.3 4 0 0 4 4 3 2 AAA domain APS_kinase PF01583.15 AIF84533.1 - 0.0003 20.4 0.8 0.28 10.8 0.0 3.1 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_15 PF13175.1 AIF84533.1 - 0.00043 19.4 2.0 2.4 7.0 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.18 AIF84533.1 - 0.00057 19.8 0.2 1.7 8.6 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase T2SE PF00437.15 AIF84533.1 - 0.00081 18.3 0.1 0.68 8.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein KaiC PF06745.8 AIF84533.1 - 0.0013 17.9 0.1 0.69 8.9 0.0 2.7 2 0 0 2 2 2 1 KaiC Viral_helicase1 PF01443.13 AIF84533.1 - 0.0018 17.8 0.0 0.22 10.9 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 AIF84533.1 - 0.0018 17.2 0.0 1.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 AIF84533.1 - 0.0021 17.5 0.8 0.43 9.9 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 AIF84533.1 - 0.0026 17.2 0.2 1.9 7.8 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 AIF84533.1 - 0.0031 17.2 0.3 2.2 7.9 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 AIF84533.1 - 0.0035 16.2 0.7 5.7 5.7 0.0 3.4 3 0 0 3 3 3 0 NB-ARC domain Arch_ATPase PF01637.13 AIF84533.1 - 0.0071 16.0 0.7 1.6 8.3 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase ArgK PF03308.11 AIF84533.1 - 0.0076 15.0 0.2 4.5 5.9 0.1 2.8 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 AIF84533.1 - 0.013 15.6 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 AIF84533.1 - 0.024 14.3 2.9 2.9 7.5 0.0 3.3 4 1 1 5 5 2 0 NTPase AAA_28 PF13521.1 AIF84533.1 - 0.025 14.5 0.4 9.2 6.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.4 AIF84533.1 - 0.032 13.1 0.3 5.3 5.8 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 AIF84533.1 - 0.035 13.6 0.1 9.8 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 AIF84533.1 - 0.079 12.4 0.2 2 7.8 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain SbcCD_C PF13558.1 AIF84533.1 - 0.14 12.1 0.6 5.9 6.8 0.0 3.4 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit BCA_ABC_TP_C PF12399.3 AIF84533.1 - 0.14 11.8 1.7 0.15 11.7 0.1 2.0 2 0 0 2 2 1 0 Branched-chain amino acid ATP-binding cassette transporter DUF87 PF01935.12 AIF84533.1 - 0.43 10.3 5.8 5.9 6.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function DUF87 zf-FPG_IleRS PF06827.9 AIF84533.1 - 2.9 7.6 10.0 4 7.1 0.1 3.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS UvrC_HhH_N PF08459.6 AIF84534.1 - 2.4e-43 147.3 0.0 5.8e-43 146.1 0.0 1.7 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.19 AIF84534.1 - 1e-10 41.7 1.6 2e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain UVR PF02151.14 AIF84534.1 - 2.3e-06 26.9 2.5 2.3e-06 26.9 1.7 1.9 2 0 0 2 2 2 1 UvrB/uvrC motif DUF294 PF03445.8 AIF84535.1 - 0.046 13.3 0.2 0.053 13.1 0.2 1.1 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Motilin_ghrelin PF04644.7 AIF84535.1 - 0.11 12.3 1.5 0.16 11.7 1.0 1.2 1 0 0 1 1 1 0 Motilin/ghrelin AlaDh_PNT_N PF05222.10 AIF84537.1 - 8e-39 132.7 0.1 1.5e-38 131.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 AIF84537.1 - 5.9e-15 55.2 2.6 1.5e-13 50.6 0.5 2.8 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 AIF84537.1 - 1.4e-05 25.2 0.1 3.4e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.9 AIF84537.1 - 2e-05 23.2 0.4 2.9e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.15 AIF84537.1 - 0.0013 18.7 0.1 0.003 17.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 AIF84537.1 - 0.0019 17.3 0.2 0.0044 16.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 AIF84537.1 - 0.0041 17.0 0.6 0.015 15.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 AIF84537.1 - 0.0094 15.1 0.2 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 AIF84537.1 - 0.022 13.6 0.2 0.054 12.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 AIF84537.1 - 0.084 13.2 0.0 0.35 11.2 0.0 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Copper-bind PF00127.15 AIF84538.1 - 1.2e-10 41.4 0.4 1.6e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF84538.1 - 1.4e-05 24.8 0.2 4.2e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Cupredoxin-like domain W_rich_C PF07483.6 AIF84538.1 - 0.025 14.2 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain DUF1443 PF07280.6 AIF84538.1 - 2.5 7.7 5.2 13 5.4 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1443) Cupredoxin_1 PF13473.1 AIF84540.1 - 2.8e-11 43.2 0.0 3.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 AIF84540.1 - 2.8e-10 40.2 0.5 1.2e-09 38.3 0.3 1.9 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family PKD PF00801.15 AIF84540.1 - 0.52 10.0 3.2 14 5.5 2.2 2.2 1 1 0 1 1 1 0 PKD domain HTH_45 PF14947.1 AIF84541.1 - 1.1e-06 28.2 0.1 1.3e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 AIF84541.1 - 0.0041 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 MarR family DUF2680 PF10925.3 AIF84541.1 - 0.0065 16.3 0.1 0.98 9.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2680) PrgI PF12666.2 AIF84542.1 - 0.0056 16.8 0.6 0.0077 16.3 0.4 1.3 1 0 0 1 1 1 1 PrgI family protein DUF2207 PF09972.4 AIF84542.1 - 0.0064 15.1 0.1 0.0067 15.0 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3754 PF12576.3 AIF84542.1 - 0.017 14.7 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Brr6_like_C_C PF10104.4 AIF84542.1 - 0.021 14.3 2.2 0.12 11.9 0.3 2.2 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF2721 PF11026.3 AIF84542.1 - 0.029 14.0 1.5 0.15 11.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF2852 PF11014.3 AIF84542.1 - 0.04 13.8 4.3 0.83 9.6 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF677 PF05055.7 AIF84542.1 - 0.07 11.7 0.1 0.08 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF1049 PF06305.6 AIF84542.1 - 0.21 11.0 1.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TEX33 PF15400.1 AIF84542.1 - 0.23 11.8 1.8 0.37 11.2 1.2 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family CbiQ PF02361.11 AIF84542.1 - 6.2 6.3 8.9 26 4.2 6.2 1.7 1 1 0 1 1 1 0 Cobalt transport protein PIG-Y PF15159.1 AIF84542.1 - 8 6.7 8.0 1.7e+02 2.5 5.6 2.1 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF998 PF06197.8 AIF84543.1 - 0.0011 18.3 2.5 0.0011 18.3 1.8 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF998) Grp1_Fun34_YaaH PF01184.14 AIF84543.1 - 0.042 13.1 2.8 0.027 13.7 0.7 1.5 1 1 1 2 2 2 0 GPR1/FUN34/yaaH family DUF4267 PF14087.1 AIF84543.1 - 0.27 10.8 2.9 0.43 10.1 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) Tetraspannin PF00335.15 AIF84543.1 - 1 8.5 7.9 0.066 12.4 2.2 1.4 2 0 0 2 2 2 0 Tetraspanin family SnoaL_2 PF12680.2 AIF84544.1 - 0.061 13.7 3.0 0.69 10.3 2.1 2.0 1 1 0 1 1 1 0 SnoaL-like domain CcdA PF07362.7 AIF84547.1 - 0.0029 17.4 0.4 0.047 13.5 0.3 2.0 1 1 0 1 1 1 1 Post-segregation antitoxin CcdA DNA_alkylation PF08713.6 AIF84548.1 - 0.051 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 DNA alkylation repair enzyme zf-Di19 PF05605.7 AIF84549.1 - 0.0002 21.3 1.7 0.018 15.1 0.1 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.3 AIF84549.1 - 2.5 8.1 5.2 6 6.8 0.0 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain Radical_SAM PF04055.16 AIF84551.1 - 2.9e-15 56.8 0.0 5.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM PF04055.16 AIF84552.1 - 3e-11 43.7 0.0 6.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.8 AIF84552.1 - 0.007 16.1 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Trypsin_2 PF13365.1 AIF84553.1 - 8e-19 67.7 0.0 1.6e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 AIF84553.1 - 1.3e-15 57.0 7.3 9.4e-13 47.8 3.5 3.3 2 1 0 2 2 2 1 PDZ domain Trypsin PF00089.21 AIF84553.1 - 6.4e-13 48.7 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin PDZ PF00595.19 AIF84553.1 - 4.3e-05 23.6 1.1 0.0026 17.8 0.0 3.3 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S29 PF02907.10 AIF84553.1 - 0.0083 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.4 AIF84553.1 - 0.08 11.3 0.8 0.19 10.0 0.1 1.7 2 0 0 2 2 2 0 Peptidase S46 Tricorn_PDZ PF14685.1 AIF84553.1 - 0.18 11.5 0.8 13 5.6 0.0 3.1 2 1 1 3 3 3 0 Tricorn protease PDZ domain HTH_45 PF14947.1 AIF84554.1 - 2.1e-18 65.9 0.1 2.5e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.1 AIF84554.1 - 0.00054 20.2 0.0 0.00071 19.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.1 AIF84554.1 - 0.00075 19.1 0.1 0.00093 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_IclR PF09339.5 AIF84554.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Glycos_transf_2 PF00535.21 AIF84555.1 - 6e-32 110.6 0.0 8.7e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIF84555.1 - 4.7e-22 78.9 0.0 7.1e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AIF84555.1 - 1.7e-13 50.2 0.0 3.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF84555.1 - 2.2e-07 30.2 0.0 2.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AIF84555.1 - 7.1e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Polyketide_cyc2 PF10604.4 AIF84556.1 - 3.7e-13 49.8 0.1 4.2e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AIF84556.1 - 5.3e-09 36.1 0.0 7.9e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 AIF84556.1 - 0.00027 20.6 0.2 0.00041 20.0 0.1 1.2 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) DUF1857 PF08982.6 AIF84556.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) CbtA PF09490.5 AIF84557.1 - 8.6e-19 67.7 13.9 1.3e-18 67.1 9.6 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) SCF PF02404.10 AIF84557.1 - 0.16 11.1 0.2 0.82 8.8 0.0 2.0 2 0 0 2 2 2 0 Stem cell factor Acyl_transf_3 PF01757.17 AIF84557.1 - 0.25 10.1 10.6 3.4 6.4 3.5 2.2 1 1 0 1 1 1 0 Acyltransferase family DUF202 PF02656.10 AIF84557.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) CbtB PF09489.5 AIF84558.1 - 3.4e-07 30.0 6.3 7.7e-06 25.7 0.9 2.1 2 0 0 2 2 2 2 Probable cobalt transporter subunit (CbtB) DUF4443 PF14544.1 AIF84559.1 - 3.9e-09 36.3 0.0 5.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) HTH_24 PF13412.1 AIF84559.1 - 0.013 14.8 0.4 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 AIF84559.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix FeoC PF09012.5 AIF84559.1 - 0.015 15.0 0.2 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator MarR_2 PF12802.2 AIF84559.1 - 0.047 13.3 0.1 0.21 11.2 0.0 2.1 3 0 0 3 3 3 0 MarR family Ribosomal_S19e PF01090.14 AIF84559.1 - 0.059 12.8 0.4 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein S19e Thi4 PF01946.12 AIF84559.1 - 0.076 12.1 0.1 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Yae1_N PF09811.4 AIF84560.1 - 0.27 10.7 6.1 4.7 6.8 0.7 2.9 2 1 0 2 2 2 0 Essential protein Yae1, N terminal Guanylate_cyc PF00211.15 AIF84562.1 - 2.6e-16 59.5 0.0 3.4e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CBS PF00571.23 AIF84563.1 - 1.5e-26 91.8 0.9 2e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 CBS domain Usp PF00582.21 AIF84564.1 - 1.2e-28 100.0 0.6 1.5e-28 99.7 0.4 1.1 1 0 0 1 1 1 1 Universal stress protein family RDD PF06271.7 AIF84565.1 - 1.7e-20 73.3 4.6 2e-20 73.0 3.2 1.1 1 0 0 1 1 1 1 RDD family TrkH PF02386.11 AIF84565.1 - 0.12 10.9 1.2 0.14 10.7 0.8 1.1 1 0 0 1 1 1 0 Cation transport protein HTH_27 PF13463.1 AIF84566.1 - 0.0039 17.4 1.4 0.021 15.1 0.1 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain Nramp PF01566.13 AIF84569.1 - 4.7e-78 262.4 19.8 5.8e-78 262.1 13.7 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein zf-C3HC4_2 PF13923.1 AIF84572.1 - 0.083 12.9 4.8 0.52 10.3 0.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2616 PF11077.3 AIF84572.1 - 0.1 12.0 0.7 0.12 11.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Metallothio_Pro PF02069.11 AIF84572.1 - 0.11 12.3 5.0 0.33 10.8 3.5 1.7 1 1 0 1 1 1 0 Prokaryotic metallothionein LIM PF00412.17 AIF84572.1 - 3 7.9 7.6 16 5.6 5.2 1.9 1 1 0 1 1 1 0 LIM domain Phage_RpbA PF10789.4 AIF84574.1 - 0.013 15.2 0.9 4.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA TENA_THI-4 PF03070.11 AIF84575.1 - 2.6e-14 53.4 0.3 3.3e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.1 AIF84575.1 - 2.1e-12 47.1 0.3 2.8e-09 37.0 0.0 2.2 1 1 1 2 2 2 2 Iron-containing redox enzyme PH_8 PF15409.1 AIF84575.1 - 0.088 12.8 0.0 7.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3262 PF11660.3 AIF84577.1 - 2.6 8.2 6.6 0.18 11.9 0.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3262) RDM PF11002.3 AIF84578.1 - 0.034 13.8 0.3 0.044 13.4 0.2 1.2 1 0 0 1 1 1 0 RFPL defining motif (RDM) Kinocilin PF15033.1 AIF84581.1 - 0.9 9.0 4.0 2.5 7.6 0.4 2.3 1 1 1 2 2 2 0 Kinocilin protein HEPN PF05168.9 AIF84583.1 - 9.7e-08 31.9 2.4 1.6e-07 31.2 0.6 2.2 2 1 1 3 3 3 1 HEPN domain MCM PF00493.18 AIF84584.1 - 3e-60 203.7 0.0 4.9e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 AIF84584.1 - 2.2e-06 26.9 0.0 0.055 12.6 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AIF84584.1 - 3.6e-06 26.7 0.0 9.2e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AIF84584.1 - 0.00036 20.1 0.0 0.00077 19.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AIF84584.1 - 0.00054 19.4 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain KRAB PF01352.22 AIF84587.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 KRAB box COX5A PF02284.11 AIF84588.1 - 0.034 14.0 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va 6PF2K PF01591.13 AIF84589.1 - 0.17 10.9 2.9 2.7 7.0 0.3 2.1 1 1 0 2 2 2 0 6-phosphofructo-2-kinase DUF1542 PF07564.6 AIF84589.1 - 0.25 11.3 3.7 0.12 12.3 1.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DIRP PF06584.8 AIF84591.1 - 0.3 10.9 3.0 0.51 10.2 2.0 1.6 1 1 1 2 2 2 0 DIRP DZR PF12773.2 AIF84594.1 - 0.21 11.4 2.9 0.46 10.3 2.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_jaz PF12171.3 AIF84594.1 - 0.25 11.5 4.1 5 7.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Nudix_N_2 PF14803.1 AIF84594.1 - 1.1 9.0 0.1 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.1 AIF84594.1 - 1.1 8.5 5.2 7 5.9 3.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-B_box PF00643.19 AIF84594.1 - 2.5 8.0 5.2 16 5.5 3.6 1.9 1 1 1 2 2 2 0 B-box zinc finger polyprenyl_synt PF00348.12 AIF84595.1 - 4.2e-44 150.3 0.1 5.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Oxidored_q1 PF00361.15 AIF84596.1 - 1.7e-59 201.2 17.5 1.7e-59 201.2 12.1 2.6 2 1 1 3 3 3 1 NADH-Ubiquinone/plastoquinone (complex I), various chains DUF2108 PF09881.4 AIF84596.1 - 0.73 9.6 9.7 0.1 12.4 2.7 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) Oxidored_q1 PF00361.15 AIF84597.1 - 2.2e-59 200.9 29.6 3.2e-54 184.0 15.0 3.1 3 0 0 3 3 3 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 AIF84597.1 - 1.8e-08 33.7 1.1 9e-08 31.5 0.8 2.2 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q1_C PF01010.14 AIF84597.1 - 0.00081 18.9 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Oxidored_q1 PF00361.15 AIF84598.1 - 7.2e-62 209.0 26.8 7.2e-62 209.0 18.5 2.2 2 0 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q2 PF00420.19 AIF84599.1 - 4.4e-24 83.8 4.5 4.9e-24 83.7 3.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Oxidored_q1_C PF01010.14 AIF84599.1 - 0.13 11.7 1.4 0.15 11.5 1.0 1.1 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus BphX PF06139.7 AIF84599.1 - 2.6 7.6 8.0 7.3 6.1 5.5 1.7 1 1 0 1 1 1 0 BphX-like DUF2108 PF09881.4 AIF84599.1 - 4.1 7.2 9.0 0.68 9.8 2.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) Oxidored_q3 PF00499.15 AIF84600.1 - 1.2e-18 67.2 13.9 1.6e-18 66.9 9.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4040 PF13244.1 AIF84600.1 - 0.0023 17.8 13.4 0.0023 17.8 9.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4040) CD47 PF04549.9 AIF84600.1 - 2.5 8.0 8.8 4 7.4 2.2 2.6 1 1 1 2 2 2 0 CD47 transmembrane region Fer4 PF00037.22 AIF84601.1 - 3.4e-13 48.5 11.0 2.7e-09 36.2 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AIF84601.1 - 5.8e-10 39.3 8.5 1e-09 38.6 5.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF84601.1 - 4.1e-09 36.1 7.5 7.5e-09 35.2 5.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AIF84601.1 - 1.9e-08 34.0 20.5 1.2e-06 28.2 7.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIF84601.1 - 2.9e-08 33.1 11.9 6.9e-05 22.5 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 AIF84601.1 - 1.5e-07 30.9 12.2 5.2e-06 26.0 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AIF84601.1 - 5.4e-07 29.7 9.3 2.3e-06 27.7 6.9 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIF84601.1 - 1e-06 28.5 8.3 0.0023 18.1 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 AIF84601.1 - 3e-06 27.8 7.0 5.4e-06 27.0 4.9 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 AIF84601.1 - 3.3e-06 27.0 17.2 0.00014 21.8 6.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AIF84601.1 - 8e-06 26.1 6.3 0.006 16.9 0.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 AIF84601.1 - 3.1e-05 24.4 3.1 0.062 13.8 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 AIF84601.1 - 0.0044 17.4 12.4 0.0068 16.8 0.9 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.2 AIF84601.1 - 0.0058 17.1 4.0 0.0058 17.1 2.8 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.1 AIF84601.1 - 0.018 15.4 8.4 0.19 12.1 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain NADHdh PF00146.16 AIF84602.1 - 5.9e-76 255.4 18.3 9.3e-76 254.8 12.7 1.3 1 0 0 1 1 1 1 NADH dehydrogenase Complex1_49kDa PF00346.14 AIF84603.1 - 5.5e-63 212.5 0.0 6.2e-49 166.4 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Csm1 PF12539.3 AIF84603.1 - 0.0099 16.3 0.0 0.51 10.8 0.0 2.6 1 1 1 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Complex1_30kDa PF00329.14 AIF84604.1 - 1.2e-28 99.3 0.0 1.7e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit FAP PF07174.6 AIF84604.1 - 0.098 11.9 29.9 0.12 11.6 20.7 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Oxidored_q6 PF01058.17 AIF84605.1 - 4.4e-24 84.5 0.4 6.3e-24 84.0 0.3 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.14 AIF84606.1 - 1.4e-14 53.7 2.2 1.7e-14 53.4 1.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Endonuc_Holl PF10107.4 AIF84607.1 - 3.2e-15 56.1 0.1 3.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase Methyltransf_24 PF13578.1 AIF84607.1 - 0.06 14.1 0.0 0.086 13.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Endonuc_Holl PF10107.4 AIF84608.1 - 6.6e-25 87.6 0.1 7.3e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase Phe_tRNA-synt_N PF02912.13 AIF84608.1 - 0.013 15.2 0.9 0.013 15.2 0.6 2.0 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain RPEL PF02755.10 AIF84609.1 - 0.17 11.2 1.0 0.27 10.6 0.7 1.4 1 0 0 1 1 1 0 RPEL repeat Integrase_DNA PF02920.10 AIF84612.1 - 0.019 14.3 0.3 0.032 13.6 0.1 1.4 1 1 0 1 1 1 0 DNA binding domain of tn916 integrase 4HB_MCP_1 PF12729.2 AIF84612.1 - 0.019 14.3 0.9 0.019 14.3 0.6 1.0 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Elongin_A PF06881.6 AIF84612.1 - 0.063 13.6 0.2 0.066 13.6 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Cas_Cas4 PF01930.12 AIF84613.1 - 3.2e-16 59.6 0.1 3.7e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 AIF84613.1 - 3.7e-05 23.2 0.1 9.2e-05 21.9 0.0 1.5 1 1 1 2 2 2 1 PD-(D/E)XK nuclease superfamily Exo5 PF09810.4 AIF84613.1 - 0.028 13.6 0.3 0.16 11.1 0.0 2.1 2 1 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Poxvirus PF06227.7 AIF84613.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus CRISPR_Cas2 PF09827.4 AIF84614.1 - 8.6e-14 51.4 0.8 9.7e-14 51.2 0.5 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas2 Cas_Cas1 PF01867.11 AIF84615.1 - 1.4e-70 237.6 0.0 1.6e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 CRISPR associated protein Cas1 DEAD PF00270.24 AIF84617.1 - 1.3e-12 47.5 2.6 1e-10 41.3 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase HD PF01966.17 AIF84617.1 - 8.4e-07 29.0 1.6 1.6e-06 28.1 0.3 2.0 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 AIF84617.1 - 1.2e-06 27.9 0.0 4.1e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 HDOD domain Helicase_C PF00271.26 AIF84617.1 - 4e-06 26.6 0.0 3.1e-05 23.7 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AIF84617.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 2.9 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit SpoU_sub_bind PF08032.7 AIF84617.1 - 0.018 15.1 0.1 0.19 11.9 0.0 2.7 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding AAA_19 PF13245.1 AIF84617.1 - 0.021 14.5 0.0 0.089 12.5 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Cas_Cas5d PF09704.5 AIF84618.1 - 1.9e-11 43.9 0.0 2.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) DUF694 PF05107.7 AIF84619.1 - 7.2e-41 140.2 0.0 9.3e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF694) Phage_integrase PF00589.17 AIF84621.1 - 1e-05 25.3 0.2 0.00032 20.3 0.0 2.6 2 1 0 2 2 2 1 Phage integrase family HTH_24 PF13412.1 AIF84621.1 - 0.0012 18.1 0.1 0.0038 16.5 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 AIF84621.1 - 0.01 15.3 0.2 0.038 13.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain FAD_oxidored PF12831.2 AIF84623.1 - 1.4e-20 73.8 0.1 1.6e-20 73.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AIF84623.1 - 2.8e-15 56.1 5.7 3.3e-08 32.8 1.6 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AIF84623.1 - 2.2e-11 43.3 0.0 3.2e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 AIF84623.1 - 4.6e-10 39.0 0.3 3.1e-09 36.3 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 AIF84623.1 - 3.5e-09 35.6 0.7 1.4e-08 33.6 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 AIF84623.1 - 1.4e-08 34.0 4.8 9.1e-08 31.3 1.7 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 AIF84623.1 - 2e-07 30.2 1.0 2.9e-07 29.6 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AIF84623.1 - 3.8e-07 30.0 0.1 1.1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AIF84623.1 - 6.9e-07 28.2 0.7 0.028 13.0 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 AIF84623.1 - 1.1e-06 28.7 1.1 1.8e-06 28.0 0.8 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AIF84623.1 - 1.4e-06 28.5 0.1 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AIF84623.1 - 2.5e-05 23.4 1.5 6.4e-05 22.1 0.3 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 AIF84623.1 - 0.00069 19.9 0.2 0.0021 18.4 0.1 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AIF84623.1 - 0.0015 18.1 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 AIF84623.1 - 0.012 15.2 0.3 0.024 14.2 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PmbA_TldD PF01523.11 AIF84624.1 - 1.3e-60 205.1 6.5 1.6e-60 204.8 4.5 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase DUF3458 PF11940.3 AIF84624.1 - 0.0048 15.7 0.7 1.4 7.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3458) PmbA_TldD PF01523.11 AIF84625.1 - 8.9e-66 222.1 6.1 1.8e-65 221.1 4.3 1.5 1 0 0 1 1 1 1 Putative modulator of DNA gyrase GSDH PF07995.6 AIF84626.1 - 2e-51 175.0 0.0 2.8e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 AIF84626.1 - 0.0018 17.7 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Tachylectin PF14517.1 AIF84626.1 - 0.0046 16.3 0.1 1.1 8.5 0.0 2.5 2 1 0 2 2 2 2 Tachylectin Cupin_2 PF07883.6 AIF84627.1 - 2.7e-09 36.3 0.4 6.7e-08 31.9 0.3 2.2 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AIF84627.1 - 2.3e-07 30.3 0.0 3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.11 AIF84627.1 - 7.2e-05 22.2 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Auxin binding protein ARD PF03079.9 AIF84627.1 - 0.02 14.8 0.1 0.036 13.9 0.1 1.5 1 1 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.14 AIF84627.1 - 0.042 13.5 0.1 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF762 PF05555.6 AIF84627.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) adh_short PF00106.20 AIF84628.1 - 2.1e-34 118.8 0.2 2.6e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIF84628.1 - 1.2e-20 74.3 0.0 1.5e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF84628.1 - 1.4e-11 44.4 0.2 1.7e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 AIF84628.1 - 0.0064 15.6 0.0 0.089 11.9 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) FAD_binding_3 PF01494.14 AIF84628.1 - 0.0067 15.5 0.1 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 AIF84628.1 - 0.012 15.0 0.5 0.03 13.7 0.3 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 AIF84628.1 - 0.027 14.4 0.9 0.049 13.6 0.4 1.7 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 AIF84628.1 - 0.033 13.1 0.4 0.045 12.7 0.3 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 AIF84628.1 - 0.046 13.1 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Neuropeptide_S PF14993.1 AIF84628.1 - 0.054 13.1 0.3 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Neuropeptide S precursor protein 2-Hacid_dh_C PF02826.14 AIF84628.1 - 0.059 12.5 0.3 0.48 9.5 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 AIF84628.1 - 0.067 12.2 0.4 0.17 10.9 0.2 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DcuA_DcuB PF03605.9 AIF84628.1 - 0.074 11.8 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter NAD_binding_2 PF03446.10 AIF84628.1 - 0.083 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AIF84628.1 - 0.095 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AhpC-TSA PF00578.16 AIF84629.1 - 1e-11 44.5 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIF84629.1 - 1.1e-08 34.7 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 AIF84629.1 - 9.2e-08 32.1 0.1 2.6e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AIF84629.1 - 0.044 13.9 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 AIF84630.1 - 1.9e-40 137.3 0.0 2.4e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIF84630.1 - 1.2e-25 89.7 0.0 1.5e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 AIF84630.1 - 1.6e-06 28.0 0.0 3.7e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 AIF84630.1 - 0.00022 20.7 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Rubrerythrin PF02915.12 AIF84631.1 - 0.00029 21.1 2.8 0.0018 18.6 1.9 2.0 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.19 AIF84631.1 - 0.02 14.6 5.1 0.11 12.2 3.5 2.0 1 1 0 1 1 1 0 Ferritin-like domain DUF2383 PF09537.5 AIF84631.1 - 0.029 14.5 0.8 0.33 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF892 PF05974.7 AIF84631.1 - 0.093 12.5 3.5 1.3 8.8 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF892) FA_desaturase_2 PF03405.9 AIF84631.1 - 0.093 11.4 0.3 0.22 10.2 0.1 1.6 1 1 1 2 2 2 0 Fatty acid desaturase Phenol_Hydrox PF02332.13 AIF84631.1 - 0.11 11.7 0.1 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Methane/Phenol/Toluene Hydroxylase RNA_pol_N PF01194.12 AIF84633.1 - 1.1e-28 98.9 0.6 1.5e-28 98.6 0.4 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Enolase_C PF00113.17 AIF84634.1 - 3.3e-58 196.9 0.0 4.4e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AIF84634.1 - 1.8e-30 105.5 0.2 3.5e-30 104.6 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 AIF84634.1 - 0.002 18.0 0.1 0.0041 17.0 0.1 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 AIF84634.1 - 0.048 14.1 0.0 1.1 9.8 0.0 2.6 2 1 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain 5_3_exonuc_N PF02739.11 AIF84634.1 - 0.066 12.5 0.2 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain 7TMR-DISM_7TM PF07695.6 AIF84635.1 - 0.0023 17.6 11.4 0.19 11.3 0.8 2.6 2 1 0 2 2 2 2 7TM diverse intracellular signalling Tetraspannin PF00335.15 AIF84635.1 - 0.29 10.3 6.9 3.1 6.9 0.3 2.3 2 0 0 2 2 2 0 Tetraspanin family DUF1129 PF06570.6 AIF84635.1 - 0.6 9.3 5.3 0.4 9.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Acyl_transf_3 PF01757.17 AIF84635.1 - 1.2 7.9 13.4 37 2.9 8.8 2.4 1 1 0 1 1 1 0 Acyltransferase family DUF3185 PF11381.3 AIF84635.1 - 5.9 6.7 8.2 1.8 8.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) TctB PF07331.6 AIF84635.1 - 9.5 5.8 18.3 1.3 8.6 0.9 3.1 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Ribosomal_S2 PF00318.15 AIF84637.1 - 1.4e-32 112.6 0.0 7.3e-29 100.5 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 MEDS PF14417.1 AIF84638.1 - 9.9e-10 37.7 0.1 1.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain E2F_TDP PF02319.15 AIF84638.1 - 0.0013 18.2 0.0 0.0044 16.5 0.0 1.9 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Spt20 PF12090.3 AIF84638.1 - 0.019 14.3 0.1 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 Spt20 family Memo PF01875.12 AIF84639.1 - 5.5e-76 255.0 0.0 6.3e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.13 AIF84639.1 - 5.7e-06 25.5 0.0 7.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GHMP_kinases_C PF08544.8 AIF84640.1 - 5.1e-19 68.2 2.0 5.1e-19 68.2 1.4 2.2 3 0 0 3 3 3 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 AIF84640.1 - 2.7e-17 62.5 1.0 2.7e-17 62.5 0.7 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain PhoU PF01895.14 AIF84641.1 - 1.3e-15 57.5 7.8 3.5e-09 36.9 2.7 2.4 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 AIF84641.1 - 2.6e-05 23.8 0.1 5.3e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Antidote-toxin recognition MazE GHMP_kinases_N PF00288.21 AIF84642.1 - 3.7e-10 39.7 1.6 8.7e-10 38.5 1.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain UPF0075 PF03702.9 AIF84642.1 - 0.042 12.7 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) DUF137 PF02006.11 AIF84643.1 - 2.1e-75 252.0 0.9 2.8e-75 251.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF137 Pantoate_transf PF02548.10 AIF84644.1 - 8.2e-111 369.2 0.5 9.5e-111 369.0 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 AIF84644.1 - 4.3e-05 22.8 0.7 0.00021 20.5 0.5 2.1 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DFP PF04127.10 AIF84645.1 - 7e-56 188.7 5.9 5.3e-55 185.9 1.8 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.14 AIF84645.1 - 4e-28 97.6 2.8 4.5e-28 97.4 0.5 2.0 2 0 0 2 2 2 1 Flavoprotein YjeF_N PF03853.10 AIF84645.1 - 0.0025 17.4 1.1 1.8 8.1 0.0 3.1 3 1 0 3 3 3 2 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 AIF84645.1 - 0.04 13.9 0.7 0.34 10.8 0.1 2.4 2 0 0 2 2 2 0 NADH(P)-binding PrcB_C PF14343.1 AIF84646.1 - 0.007 16.0 0.1 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 PrcB C-terminal DUF1573 PF07610.6 AIF84646.1 - 0.036 13.6 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) DUF2007 PF09413.5 AIF84646.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) CARDB PF07705.6 AIF84646.1 - 0.077 13.0 0.6 1.5 8.9 0.0 2.9 1 1 1 2 2 2 0 CARDB Peptidase_M24 PF00557.19 AIF84647.1 - 1.4e-55 188.0 0.2 1.9e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AIF84647.1 - 1.1e-09 38.8 0.0 2.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain URO-D PF01208.12 AIF84647.1 - 0.063 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) AAA PF00004.24 AIF84648.1 - 1.2e-98 326.4 0.0 2.3e-48 163.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AIF84648.1 - 5.7e-22 77.4 0.6 1.7e-21 75.9 0.4 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AIF84648.1 - 4.7e-15 55.2 0.2 5.7e-08 32.0 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AIF84648.1 - 1.1e-14 54.7 0.0 6.9e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AIF84648.1 - 1.2e-14 54.5 0.2 6e-05 23.1 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AIF84648.1 - 2.6e-14 53.6 0.1 7.9e-06 25.9 0.0 4.0 2 1 2 4 4 4 2 AAA ATPase domain CDC48_2 PF02933.12 AIF84648.1 - 3.8e-14 52.0 0.0 9.9e-14 50.7 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 AIF84648.1 - 7.4e-13 49.3 0.0 1.4e-05 25.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AIF84648.1 - 1.1e-10 41.5 0.0 1.3e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AIF84648.1 - 1.8e-10 40.8 0.0 0.00041 20.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AIF84648.1 - 1.9e-10 40.2 0.0 0.00037 19.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 AIF84648.1 - 3.7e-10 39.6 1.1 0.0015 18.2 0.1 4.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AIF84648.1 - 1.3e-09 37.6 0.5 0.001 18.7 0.1 2.9 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 AIF84648.1 - 7.3e-09 34.8 0.0 0.0021 16.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 AIF84648.1 - 2.4e-08 33.6 0.2 0.0023 17.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 AIF84648.1 - 4.7e-08 33.4 0.0 0.0087 16.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 AIF84648.1 - 8.2e-07 28.1 0.0 0.036 12.9 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain Arch_ATPase PF01637.13 AIF84648.1 - 1.1e-06 28.4 0.0 0.034 13.8 0.0 3.3 2 1 1 3 3 3 2 Archaeal ATPase AAA_28 PF13521.1 AIF84648.1 - 1.7e-06 28.0 0.0 0.0058 16.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AIF84648.1 - 1.8e-06 28.0 0.1 0.058 13.5 0.0 2.8 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 AIF84648.1 - 2.4e-06 26.8 0.7 0.051 12.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI PhoH PF02562.11 AIF84648.1 - 5.5e-06 25.7 0.3 0.052 12.7 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein AAA_25 PF13481.1 AIF84648.1 - 6.9e-06 25.5 9.1 0.69 9.2 0.2 4.8 3 2 0 5 5 5 3 AAA domain Sigma54_activat PF00158.21 AIF84648.1 - 9.4e-06 25.1 0.4 0.34 10.3 0.0 4.0 4 1 0 4 4 3 2 Sigma-54 interaction domain NACHT PF05729.7 AIF84648.1 - 9.7e-06 25.3 0.1 0.13 11.9 0.0 3.7 4 0 0 4 4 4 1 NACHT domain AAA_24 PF13479.1 AIF84648.1 - 3e-05 23.7 0.6 0.032 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 AIF84648.1 - 6e-05 22.6 0.0 0.24 11.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 AIF84648.1 - 6.2e-05 22.1 0.0 0.082 11.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 AIF84648.1 - 0.00012 21.7 1.0 0.37 10.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.10 AIF84648.1 - 0.00013 21.7 0.2 0.39 10.4 0.0 3.3 2 1 1 3 3 3 1 NTPase ABC_tran PF00005.22 AIF84648.1 - 0.00014 22.1 0.0 0.31 11.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.8 AIF84648.1 - 0.00016 20.7 0.0 0.25 10.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 AIF84648.1 - 0.00018 21.5 0.0 0.7 9.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Molydop_binding PF01568.16 AIF84648.1 - 0.00029 20.6 0.1 0.005 16.6 0.0 2.6 2 1 1 3 3 2 1 Molydopterin dinucleotide binding domain KaiC PF06745.8 AIF84648.1 - 0.00044 19.4 0.6 1.5 7.8 0.0 3.4 2 1 1 3 3 3 1 KaiC AAA_11 PF13086.1 AIF84648.1 - 0.00055 19.5 0.1 0.65 9.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 AIF84648.1 - 0.00065 19.4 0.0 2.7 7.5 0.0 3.4 3 1 0 3 3 3 1 Bacterial dnaA protein AFG1_ATPase PF03969.11 AIF84648.1 - 0.00095 18.0 0.1 0.77 8.4 0.0 2.6 2 1 0 2 2 2 2 AFG1-like ATPase Parvo_NS1 PF01057.12 AIF84648.1 - 0.0013 17.6 0.1 0.92 8.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 T2SE PF00437.15 AIF84648.1 - 0.0034 16.3 0.0 2.7 6.8 0.0 2.7 3 0 0 3 3 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 AIF84648.1 - 0.0047 16.4 0.2 2.2 7.7 0.0 2.8 3 1 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 AIF84648.1 - 0.006 16.2 0.0 2.4 7.7 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 AIF84648.1 - 0.0072 15.8 0.0 0.96 8.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 AIF84648.1 - 0.0074 16.1 0.0 5.4 6.8 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.17 AIF84648.1 - 0.0091 15.8 0.0 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin2 PF13189.1 AIF84648.1 - 0.012 15.5 0.5 0.082 12.8 0.0 2.6 4 0 0 4 4 2 0 Cytidylate kinase-like family KAP_NTPase PF07693.9 AIF84648.1 - 0.052 12.5 0.0 7.6 5.4 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain Guanylate_kin PF00625.16 AIF84648.1 - 0.054 12.9 0.2 7.4 5.9 0.0 3.4 2 1 1 3 3 3 0 Guanylate kinase KTI12 PF08433.5 AIF84648.1 - 0.057 12.6 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DAP3 PF10236.4 AIF84648.1 - 0.067 12.1 0.0 9 5.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 CPT PF07931.7 AIF84648.1 - 0.068 12.7 0.0 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Torsin PF06309.6 AIF84648.1 - 0.11 12.3 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Torsin cobW PF02492.14 AIF84648.1 - 0.11 11.8 0.1 11 5.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RibD_C PF01872.12 AIF84649.1 - 1.1e-16 61.0 0.0 6.2e-11 42.2 0.0 2.0 1 1 1 2 2 2 2 RibD C-terminal domain DHFR_1 PF00186.14 AIF84649.1 - 2.9e-10 39.9 0.0 3.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Gly_acyl_tr_C PF08444.5 AIF84649.1 - 0.14 12.1 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Aminotran_5 PF00266.14 AIF84650.1 - 2.5e-33 115.3 0.0 3.3e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AIF84650.1 - 0.0037 15.6 0.0 0.0055 15.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FliE PF02049.13 AIF84652.1 - 0.0059 16.6 0.0 0.0081 16.1 0.0 1.2 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE DUF742 PF05331.6 AIF84652.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Osmo_CC PF08946.5 AIF84652.1 - 0.05 13.6 0.3 0.083 12.9 0.2 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Abhydrolase_6 PF12697.2 AIF84654.1 - 1.1e-33 117.0 0.1 1.3e-33 116.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIF84654.1 - 5e-24 84.7 0.1 1.2e-23 83.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 AIF84654.1 - 6.8e-06 25.7 0.0 0.0015 18.1 0.0 2.2 1 1 1 2 2 2 2 Serine hydrolase Abhydrolase_1 PF00561.15 AIF84654.1 - 0.00039 20.0 1.8 0.016 14.7 0.4 2.7 1 1 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 AIF84654.1 - 0.007 15.2 0.0 0.029 13.2 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 AIF84654.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 AIF84654.1 - 0.13 12.1 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase DAO PF01266.19 AIF84655.1 - 1.8e-14 53.4 4.5 5.3e-14 51.8 2.3 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIF84655.1 - 6.8e-14 51.6 1.6 8.1e-14 51.4 0.3 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 AIF84655.1 - 7.2e-13 48.4 0.2 1.2e-11 44.3 0.2 2.5 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 AIF84655.1 - 4.4e-10 38.5 0.8 0.00012 20.7 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 AIF84655.1 - 1.7e-09 37.8 0.2 0.00031 20.6 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AIF84655.1 - 2.6e-07 29.8 3.2 1.1e-05 24.4 0.5 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 AIF84655.1 - 1.3e-06 27.6 1.3 2.2e-06 26.7 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 AIF84655.1 - 1.9e-06 28.0 0.3 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AIF84655.1 - 6.8e-06 25.3 0.1 1.5e-05 24.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AIF84655.1 - 7.2e-06 25.2 0.5 1.2e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 AIF84655.1 - 3.5e-05 23.6 0.5 0.22 11.2 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 AIF84655.1 - 0.00011 22.5 2.1 0.00029 21.1 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AIF84655.1 - 0.00017 20.6 1.0 0.021 13.7 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 AIF84655.1 - 0.00066 18.8 3.7 0.0011 18.0 1.5 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 AIF84655.1 - 0.0062 16.2 0.5 0.011 15.4 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AIF84655.1 - 0.0084 15.5 0.1 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 AIF84655.1 - 0.0096 14.5 0.4 0.014 14.0 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase RibD_C PF01872.12 AIF84656.1 - 1.3e-25 90.1 0.0 2.4e-25 89.3 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain PP1_inhibitor PF05361.7 AIF84657.1 - 0.011 15.4 0.5 0.015 15.0 0.3 1.2 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Chorion_3 PF05387.6 AIF84659.1 - 0.58 9.5 3.5 0.63 9.4 2.4 1.1 1 0 0 1 1 1 0 Chorion family 3 DUF1183 PF06682.7 AIF84660.1 - 0.0092 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Peptidase_S24 PF00717.18 AIF84662.1 - 3.9e-09 36.0 0.5 6.7e-09 35.2 0.4 1.4 1 0 0 1 1 1 1 Peptidase S24-like SnoaL_2 PF12680.2 AIF84663.1 - 8.6e-09 35.7 0.0 1e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF1250 PF06855.7 AIF84663.1 - 0.018 14.5 0.5 0.05 13.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) DUF4440 PF14534.1 AIF84663.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) FKBP_C PF00254.23 AIF84664.1 - 4.8e-14 52.1 0.0 1.1e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Fe-S_biosyn PF01521.15 AIF84665.1 - 6.3e-26 90.5 0.0 7.1e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TPPK_C PF12555.3 AIF84666.1 - 0.022 14.4 0.4 0.029 14.0 0.3 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal YndJ PF14158.1 AIF84666.1 - 0.029 13.4 0.2 0.03 13.3 0.1 1.0 1 0 0 1 1 1 0 YndJ-like protein HTH_5 PF01022.15 AIF84667.1 - 2.3e-05 23.9 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AIF84667.1 - 6.8e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_45 PF14947.1 AIF84667.1 - 0.00016 21.3 0.1 0.0003 20.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF84667.1 - 0.047 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_27 PF13463.1 AIF84667.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain TIMP PF00965.12 AIF84668.1 - 7.1e-05 22.4 0.1 9.7e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Bac_luciferase PF00296.15 AIF84669.1 - 3.9e-60 203.5 0.0 5.2e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pyridox_oxidase PF01243.15 AIF84670.1 - 3.3e-13 49.4 0.0 4.8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF84670.1 - 2.3e-06 27.4 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AsnC_trans_reg PF01037.16 AIF84671.1 - 1.7e-13 50.0 0.2 1.8e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 AsnC family HMA PF00403.21 AIF84671.1 - 0.15 12.2 0.5 0.35 11.0 0.4 1.8 1 1 0 1 1 1 0 Heavy-metal-associated domain Gln-synt_C PF00120.19 AIF84672.1 - 4.4e-76 255.4 0.0 5.5e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AIF84672.1 - 2e-15 56.1 0.0 7.3e-15 54.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain HTH_24 PF13412.1 AIF84673.1 - 7.8e-16 57.1 0.0 1.7e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF84673.1 - 1.4e-15 56.5 0.0 2.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 AIF84673.1 - 1.1e-11 44.2 0.1 1.9e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 AsnC family TrmB PF01978.14 AIF84673.1 - 4.4e-06 26.3 0.3 1.1e-05 25.0 0.1 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.14 AIF84673.1 - 4.5e-06 26.5 0.1 9.5e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.15 AIF84673.1 - 7.1e-06 25.5 0.0 2.9e-05 23.6 0.0 2.0 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_28 PF13518.1 AIF84673.1 - 3.8e-05 23.6 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 AIF84673.1 - 6.6e-05 22.3 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 AIF84673.1 - 8.2e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain MarR PF01047.17 AIF84673.1 - 0.00013 21.6 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 AIF84673.1 - 0.00022 20.9 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.7 AIF84673.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.8 1 1 0 1 1 1 1 HTH domain Rrf2 PF02082.15 AIF84673.1 - 0.00064 19.7 0.1 0.0027 17.7 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.2 AIF84673.1 - 0.00077 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_30 PF13556.1 AIF84673.1 - 0.0044 16.5 0.0 0.0098 15.4 0.0 1.6 2 0 0 2 2 1 1 PucR C-terminal helix-turn-helix domain HTH_10 PF04967.7 AIF84673.1 - 0.0058 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 HTH DNA binding domain Sigma70_r4_2 PF08281.7 AIF84673.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.1 AIF84673.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain GntR PF00392.16 AIF84673.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family TetR_N PF00440.18 AIF84673.1 - 0.018 14.6 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_29 PF13551.1 AIF84673.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.5 AIF84673.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_40 PF14493.1 AIF84673.1 - 0.023 14.9 0.1 0.041 14.1 0.1 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain Trp_repressor PF01371.14 AIF84673.1 - 0.028 14.3 0.1 0.062 13.2 0.0 1.7 2 0 0 2 2 1 0 Trp repressor protein HTH_CodY PF08222.6 AIF84673.1 - 0.037 13.3 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_Mga PF08280.6 AIF84673.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_1 PF00126.22 AIF84673.1 - 0.041 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Cdc6_C PF09079.6 AIF84673.1 - 0.047 13.4 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal HTH_7 PF02796.10 AIF84673.1 - 0.088 12.6 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_34 PF13601.1 AIF84673.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain ELFV_dehydrog PF00208.16 AIF84674.1 - 2.5e-74 249.9 5.1 3.6e-74 249.4 3.2 1.5 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 AIF84674.1 - 5.4e-56 187.7 0.0 9.6e-56 186.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 AIF84674.1 - 0.056 12.5 0.2 0.11 11.6 0.2 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MttA_Hcf106 PF02416.11 AIF84675.1 - 3.4e-12 45.2 0.3 5.1e-12 44.7 0.2 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family Translin PF01997.11 AIF84676.1 - 2e-26 92.8 0.1 2.5e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Translin family IF-2 PF11987.3 AIF84676.1 - 0.046 13.6 0.2 0.1 12.4 0.1 1.8 1 1 0 1 1 1 0 Translation-initiation factor 2 Hjc PF01870.13 AIF84677.1 - 1.7e-08 33.9 0.0 2.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) VRR_NUC PF08774.6 AIF84677.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 VRR-NUC domain Cyclophil_like PF04126.8 AIF84678.1 - 1.8e-30 105.0 0.0 2.1e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like DUF3830 PF12903.2 AIF84678.1 - 0.0052 16.1 0.0 0.009 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3830) SNase PF00565.12 AIF84679.1 - 3.1e-06 27.4 0.0 5.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Y_Y_Y PF07495.8 AIF84679.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Y_Y_Y domain TFIIB PF00382.14 AIF84680.1 - 1.9e-31 107.6 1.4 7.3e-15 54.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AIF84680.1 - 2.2e-11 42.8 0.2 3.8e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.11 AIF84680.1 - 3e-05 23.2 0.1 0.0016 17.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.1 AIF84680.1 - 0.00034 20.0 0.2 0.0022 17.4 0.0 2.5 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AIF84680.1 - 0.0026 17.3 0.5 0.024 14.2 0.1 2.5 2 0 0 2 2 2 1 HTH domain LacI PF00356.16 AIF84680.1 - 0.0026 17.3 1.3 0.64 9.6 0.0 3.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family Rrf2 PF02082.15 AIF84680.1 - 0.0035 17.4 0.2 4.4 7.4 0.0 2.7 2 1 0 2 2 2 2 Transcriptional regulator HARE-HTH PF05066.8 AIF84680.1 - 0.01 16.1 0.1 0.043 14.1 0.0 2.0 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain Sigma70_r4_2 PF08281.7 AIF84680.1 - 0.02 14.3 0.1 0.098 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 AIF84680.1 - 0.022 14.4 0.3 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.1 AIF84680.1 - 0.034 13.5 0.9 0.13 11.6 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding GerE PF00196.14 AIF84680.1 - 0.054 12.8 0.2 0.47 9.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family TetR_N PF00440.18 AIF84680.1 - 0.09 12.4 0.1 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family YibE_F PF07907.6 AIF84680.1 - 0.1 11.7 0.1 0.24 10.5 0.0 1.5 2 0 0 2 2 2 0 YibE/F-like protein HTH_Tnp_ISL3 PF13542.1 AIF84680.1 - 0.13 11.4 0.4 1.3 8.2 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 SCIMP PF15050.1 AIF84680.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 SCIMP protein Cation_efflux PF01545.16 AIF84681.1 - 1.2e-68 231.3 21.2 2.4e-54 184.3 6.0 3.0 2 1 1 3 3 3 3 Cation efflux family AMP-binding_C_2 PF14535.1 AIF84681.1 - 0.00024 21.0 3.7 0.0048 16.9 0.1 3.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain DUF1319 PF07028.6 AIF84681.1 - 0.00079 19.6 1.4 0.13 12.4 0.1 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF1319) BON PF04972.12 AIF84681.1 - 0.63 9.8 4.5 0.33 10.7 0.2 2.7 3 0 0 3 3 3 0 BON domain NMN_transporter PF04973.7 AIF84681.1 - 1.9 7.9 8.5 0.17 11.2 0.5 2.5 2 1 1 3 3 3 0 Nicotinamide mononucleotide transporter Asp23 PF03780.8 AIF84681.1 - 4.3 7.6 11.1 26 5.1 1.5 4.2 3 2 0 3 3 3 0 Asp23 family Carb_kinase PF01256.12 AIF84682.1 - 4.4e-40 137.4 0.4 5.2e-40 137.2 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 AIF84682.1 - 1.8e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 AIF84682.1 - 0.0085 15.3 0.3 0.028 13.6 0.2 1.9 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase adh_short PF00106.20 AIF84683.1 - 8.1e-30 103.9 0.0 1.1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIF84683.1 - 4.3e-13 49.5 0.1 5.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF84683.1 - 3e-11 43.3 0.0 4.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AIF84683.1 - 3e-07 30.6 0.0 1.1e-06 28.8 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 AIF84683.1 - 4.5e-07 29.2 0.0 6.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 AIF84683.1 - 0.00049 19.6 0.0 0.00087 18.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AIF84683.1 - 0.0046 16.7 0.6 0.01 15.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase tRNA_bind PF01588.15 AIF84684.1 - 5.5e-20 71.0 0.0 7.5e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain PAC2 PF09754.4 AIF84685.1 - 4.8e-26 91.9 0.0 5.6e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 PAC2 family NAD_binding_2 PF03446.10 AIF84686.1 - 1.2e-36 126.0 0.6 2.4e-36 125.0 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AIF84686.1 - 3.8e-26 91.5 0.6 1.4e-25 89.7 0.4 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 AIF84686.1 - 8.1e-06 26.1 0.3 8.3e-05 22.9 0.1 2.5 1 1 2 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 AIF84686.1 - 0.0002 21.0 0.0 0.53 9.9 0.0 2.3 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AIF84686.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding CK2S PF15011.1 AIF84687.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate Radical_SAM PF04055.16 AIF84688.1 - 3.7e-12 46.7 0.8 4.6e-12 46.4 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 AIF84688.1 - 0.00051 20.0 0.2 0.0013 18.7 0.1 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AIF84688.1 - 0.0036 17.4 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Herpes_UL3 PF03369.8 AIF84688.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL3 protein DUF77 PF01910.12 AIF84688.1 - 0.051 13.2 0.0 1.8 8.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF77 DUF1848 PF08902.6 AIF84688.1 - 0.3 10.5 3.6 0.18 11.3 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) zf-C2HC_2 PF13913.1 AIF84689.1 - 0.0072 15.9 0.3 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type Sgf11 PF08209.6 AIF84689.1 - 0.038 13.3 0.1 0.038 13.3 0.1 1.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.1 AIF84689.1 - 0.071 12.6 1.1 0.14 11.6 0.3 1.6 1 1 1 2 2 2 0 zinc-ribbon domain zf-CCHC_5 PF14787.1 AIF84689.1 - 0.089 12.2 0.6 0.15 11.5 0.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Zn-ribbon_8 PF09723.5 AIF84689.1 - 0.16 11.9 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 AIF84689.1 - 0.33 10.2 2.0 0.5 9.6 1.4 1.5 1 1 0 1 1 1 0 zinc-ribbon domain NUDIX PF00293.23 AIF84690.1 - 2.2e-22 79.1 0.0 2.7e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 AIF84690.1 - 0.037 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain Coatomer_E PF04733.9 AIF84691.1 - 0.028 13.6 0.5 0.039 13.1 0.4 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit Trns_repr_metal PF02583.12 AIF84691.1 - 0.11 12.6 2.6 3.8 7.7 0.1 2.6 2 1 1 3 3 3 0 Metal-sensitive transcriptional repressor UPF0051 PF01458.12 AIF84692.1 - 5.8e-72 241.8 0.3 8.6e-72 241.3 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Pico_P1A PF02226.11 AIF84692.1 - 0.049 13.3 0.3 14 5.4 0.0 2.8 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) UPF0051 PF01458.12 AIF84693.1 - 2.1e-57 194.2 0.3 2.9e-57 193.7 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Rieske PF00355.21 AIF84694.1 - 4.3e-16 58.2 0.0 4.8e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AIF84694.1 - 1.2e-13 50.6 0.0 1.4e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Aminotran_5 PF00266.14 AIF84695.1 - 3.5e-153 509.7 0.4 4e-153 509.5 0.3 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIF84695.1 - 0.00027 20.1 0.0 0.00075 18.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AIF84695.1 - 0.0016 16.7 0.0 0.0025 16.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AIF84695.1 - 0.0031 16.5 0.1 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.8 AIF84695.1 - 0.0056 15.4 0.1 0.017 13.8 0.0 1.6 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase NifU_N PF01592.11 AIF84696.1 - 9.1e-33 112.9 0.0 1e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Lip_prot_lig_C PF10437.4 AIF84696.1 - 0.029 14.0 0.3 0.048 13.3 0.1 1.6 1 1 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DUF3647 PF12363.3 AIF84697.1 - 0.0021 18.1 0.1 0.74 9.9 0.0 2.2 1 1 1 2 2 2 2 Phage protein DZR PF12773.2 AIF84697.1 - 0.039 13.7 1.1 0.058 13.2 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF1002 PF06207.6 AIF84697.1 - 0.085 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Peptidase_C69 PF03577.10 AIF84697.1 - 0.09 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C69 HypA PF01155.14 AIF84697.1 - 0.12 12.0 0.8 0.18 11.5 0.6 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AIF84697.1 - 0.39 10.7 3.4 1.5 8.8 2.3 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Opy2 PF09463.5 AIF84697.1 - 2 8.6 4.9 15 5.7 0.3 2.2 2 0 0 2 2 2 0 Opy2 protein PAP2 PF01569.16 AIF84698.1 - 1.2e-19 70.2 7.2 1.2e-19 70.2 5.0 2.3 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 AIF84698.1 - 6.3e-06 25.8 3.5 6.3e-06 25.8 2.4 1.7 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 AIF84698.1 - 0.05 13.8 0.6 0.05 13.8 0.4 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DUF4064 PF13273.1 AIF84698.1 - 0.6 10.2 9.6 3.9 7.6 2.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 AIF84698.1 - 1.2 8.5 5.4 13 5.1 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) CAP18_C PF12153.3 AIF84699.1 - 0.83 9.3 2.9 0.84 9.3 0.3 2.1 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) DAO PF01266.19 AIF84700.1 - 8.6e-07 28.1 0.2 0.0051 15.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AIF84700.1 - 1.5e-06 27.3 0.3 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 AIF84700.1 - 0.012 14.5 0.1 0.02 13.8 0.1 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 AIF84700.1 - 0.012 14.2 0.1 0.25 9.9 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GDI PF00996.13 AIF84700.1 - 0.014 13.7 0.0 0.024 12.9 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 AIF84700.1 - 0.019 14.1 1.1 0.077 12.0 0.8 2.0 2 1 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 AIF84700.1 - 0.053 12.6 0.1 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AIF84700.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AIF84700.1 - 0.18 10.2 1.1 0.34 9.3 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein HAD_2 PF13419.1 AIF84701.1 - 1.6e-16 61.0 0.0 2.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AIF84701.1 - 5e-12 45.3 0.0 7.9e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AIF84701.1 - 5.1e-08 33.5 0.0 5.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 AIF84701.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase DUF962 PF06127.6 AIF84702.1 - 0.00047 19.9 0.2 0.00062 19.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) HIT PF01230.18 AIF84703.1 - 1.2e-25 89.9 0.1 1.5e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AIF84703.1 - 1.6e-16 60.5 0.0 2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AIF84703.1 - 0.0024 17.4 0.1 0.0046 16.5 0.0 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF2443 PF10398.4 AIF84704.1 - 0.095 12.5 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) PAPS_reduct PF01507.14 AIF84705.1 - 5.6e-44 150.0 0.0 7e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.12 AIF84706.1 - 1.4e-88 295.8 0.5 1.9e-88 295.4 0.3 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 AIF84706.1 - 1.5e-39 135.0 0.0 2.4e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain He_PIG PF05345.7 AIF84707.1 - 1.1e-25 89.3 40.1 4.4e-10 39.4 2.3 18.3 16 4 0 16 16 16 5 Putative Ig domain CHB_HEX_C PF03174.8 AIF84707.1 - 2.9e-19 68.6 9.0 2.9e-19 68.6 6.2 7.7 8 0 0 8 8 8 1 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C_1 PF13290.1 AIF84707.1 - 3.2e-17 62.0 6.5 3.2e-17 62.0 4.5 7.1 7 0 0 7 7 7 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIF84707.1 - 4.3e-15 55.5 7.3 4.3e-15 55.5 5.0 5.4 5 0 0 5 5 5 1 Fn3 associated Big_3_4 PF13754.1 AIF84707.1 - 4.5e-06 26.8 9.9 6.4e-05 23.1 0.9 20.3 18 4 3 22 22 22 6 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.8 AIF84707.1 - 3.1e-05 23.6 1.9 0.61 9.8 0.0 4.9 4 0 0 4 4 4 2 Y_Y_Y domain Mo-co_dimer PF03404.11 AIF84707.1 - 5.1e-05 22.9 0.6 0.42 10.2 0.0 2.9 1 1 1 2 2 2 2 Mo-co oxidoreductase dimerisation domain DUF4625 PF15418.1 AIF84707.1 - 0.00023 21.2 0.3 43 4.2 0.0 6.4 5 1 1 6 6 6 0 Domain of unknown function (DUF4625) Jag_N PF14804.1 AIF84707.1 - 0.00048 20.0 0.0 38 4.3 0.0 5.4 5 0 0 5 5 5 0 Jag N-terminus PKD PF00801.15 AIF84707.1 - 0.32 10.7 0.0 0.32 10.7 0.0 15.1 12 3 1 13 13 13 0 PKD domain HTH_5 PF01022.15 AIF84711.1 - 1.8e-09 37.0 0.0 3.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AIF84711.1 - 1.6e-08 34.2 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AIF84711.1 - 8.3e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AIF84711.1 - 0.00018 20.8 0.1 0.00045 19.5 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 AIF84711.1 - 0.0004 20.1 0.3 0.00065 19.4 0.2 1.4 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_11 PF08279.7 AIF84711.1 - 0.00087 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 HTH domain Phage_rep_org_N PF09681.5 AIF84711.1 - 0.0088 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal phage replisome organiser (Phage_rep_org_N) B-block_TFIIIC PF04182.7 AIF84711.1 - 0.011 15.5 0.0 0.059 13.2 0.0 2.0 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Nup35_RRM PF05172.8 AIF84711.1 - 0.035 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HTH_29 PF13551.1 AIF84711.1 - 0.059 13.5 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix MarR_2 PF12802.2 AIF84711.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 MarR family LexA_DNA_bind PF01726.11 AIF84711.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Penicillinase_R PF03965.11 AIF84711.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor DUF3179 PF11376.3 AIF84713.1 - 6.5e-91 304.1 0.1 2.6e-90 302.2 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3179) DUF898 PF05987.8 AIF84715.1 - 0.11 11.3 11.6 0.15 10.9 8.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Trp_oprn_chp PF09534.5 AIF84715.1 - 2.6 7.6 6.4 0.71 9.4 2.3 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3816 PF12822.2 AIF84715.1 - 4.2 7.2 26.3 17 5.2 18.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Mito_carr PF00153.22 AIF84715.1 - 5.6 6.7 14.6 1.1 8.9 3.1 3.5 1 1 2 3 3 3 0 Mitochondrial carrier protein DUF4407 PF14362.1 AIF84715.1 - 5.9 5.7 6.8 8.3 5.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1757 PF08560.5 AIF84715.1 - 8.8 5.9 8.8 3.8 7.1 1.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1757) DUF1887 PF09002.6 AIF84716.1 - 0.0077 14.6 0.1 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) WAK_assoc PF14380.1 AIF84717.1 - 0.13 12.8 0.2 0.23 11.9 0.0 1.4 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal HTH_10 PF04967.7 AIF84718.1 - 8.9e-18 63.6 0.1 1.5e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 HTH DNA binding domain HTH_5 PF01022.15 AIF84718.1 - 0.022 14.4 0.2 0.074 12.7 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AIF84718.1 - 0.029 14.0 0.3 0.09 12.4 0.1 2.0 2 0 0 2 2 2 0 MarR family Sigma70_r4_2 PF08281.7 AIF84718.1 - 0.1 12.0 1.2 1 8.8 0.8 2.2 1 1 0 1 1 1 0 Sigma-70, region 4 MerB PF03243.10 AIF84719.1 - 8.7e-40 135.5 0.0 1.3e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Alkylmercury lyase HTH_15 PF12324.3 AIF84719.1 - 0.00025 20.6 0.5 0.00088 18.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase DUF1464 PF07318.7 AIF84721.1 - 0.12 11.1 0.2 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) IBV_3C PF03620.8 AIF84721.1 - 2.2 8.2 4.5 2.4 8.0 0.1 2.4 1 1 1 2 2 2 0 IBV 3C protein TNF PF00229.13 AIF84722.1 - 0.0069 15.9 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 AIF84722.1 - 0.051 13.5 0.1 0.084 12.8 0.0 1.4 1 1 0 1 1 1 0 C1q domain HTH_45 PF14947.1 AIF84723.1 - 4.9e-20 71.1 1.2 5.9e-20 70.8 0.8 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF84723.1 - 0.00038 20.1 0.1 0.00044 19.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_27 PF13463.1 AIF84723.1 - 0.0037 17.5 0.0 0.0054 17.0 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.12 AIF84723.1 - 0.0091 15.6 0.1 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix SinI PF08671.5 AIF84723.1 - 0.15 11.5 0.4 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Anti-repressor SinI UPF0184 PF03670.8 AIF84724.1 - 0.053 13.6 1.9 1.6 8.9 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Sec5 PF15469.1 AIF84724.1 - 0.098 12.3 0.5 1.9 8.1 0.2 2.3 1 1 1 2 2 2 0 Exocyst complex component Sec5 TPR_12 PF13424.1 AIF84724.1 - 1 9.3 11.7 4.5 7.2 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HhH-GPD PF00730.20 AIF84726.1 - 5.3e-27 94.2 0.0 7.7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AIF84726.1 - 5.4e-09 35.2 0.2 9.3e-08 31.3 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 AIF84726.1 - 6.6e-06 26.2 0.2 0.00032 20.8 0.2 2.8 2 1 0 2 2 2 1 Helix-hairpin-helix domain DUF2400 PF09674.5 AIF84726.1 - 0.0028 17.3 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) HHH_2 PF12826.2 AIF84726.1 - 0.019 14.8 0.0 1.4 8.8 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix motif PDDEXK_1 PF12705.2 AIF84726.1 - 0.087 12.1 0.1 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF521 PF04412.8 AIF84727.1 - 5.8e-109 364.2 0.3 8.9e-109 363.6 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 AIF84728.1 - 9.5e-29 98.9 0.1 1.5e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF126 TF_Zn_Ribbon PF08271.7 AIF84729.1 - 6.3e-07 28.6 0.3 9.4e-07 28.0 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 AIF84729.1 - 0.00038 20.0 0.5 0.00064 19.3 0.2 1.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain DZR PF12773.2 AIF84729.1 - 0.0038 17.0 0.4 0.0063 16.3 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 AIF84729.1 - 0.0045 16.9 1.5 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 AIF84729.1 - 0.015 15.1 0.4 0.023 14.5 0.3 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain FYDLN_acid PF09538.5 AIF84729.1 - 0.018 15.5 1.4 0.024 15.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nudix_N_2 PF14803.1 AIF84729.1 - 0.023 14.3 3.8 0.2 11.3 2.7 2.1 1 1 0 1 1 1 0 Nudix N-terminal Zn_Tnp_IS91 PF14319.1 AIF84729.1 - 0.035 13.6 0.1 0.048 13.1 0.0 1.3 1 1 0 1 1 1 0 Transposase zinc-binding domain zf-IS66 PF13005.2 AIF84729.1 - 0.045 13.7 0.3 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Prim_Zn_Ribbon PF08273.7 AIF84729.1 - 0.063 13.3 1.0 0.12 12.4 0.7 1.4 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase UPF0547 PF10571.4 AIF84729.1 - 0.084 12.5 0.7 0.17 11.6 0.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 AIF84729.1 - 0.12 12.2 0.3 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbons FYVE PF01363.16 AIF84729.1 - 0.13 12.1 0.4 0.14 12.0 0.3 1.2 1 1 0 1 1 1 0 FYVE zinc finger DUF1272 PF06906.6 AIF84729.1 - 0.21 11.4 1.8 0.82 9.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 AIF84729.1 - 0.22 10.7 5.2 1.2 8.4 3.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-Mss51 PF13824.1 AIF84729.1 - 0.24 11.3 2.2 0.53 10.1 1.5 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PhnA_Zn_Ribbon PF08274.7 AIF84729.1 - 0.41 10.4 3.0 1.5 8.6 2.1 1.8 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-C4_Topoisom PF01396.14 AIF84729.1 - 1.5 8.3 4.3 3.9 7.0 2.9 1.8 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF1610 PF07754.6 AIF84729.1 - 3.2 7.9 6.3 22 5.3 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.1 AIF84729.1 - 9 5.9 9.0 1.2e+02 2.3 6.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain ATP_bind_3 PF01171.15 AIF84730.1 - 9e-20 70.9 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 AIF84730.1 - 0.0059 15.5 0.1 0.0083 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 AIF84730.1 - 0.026 13.0 0.0 0.038 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF4206 PF13901.1 AIF84730.1 - 6.5 6.2 7.4 4.8 6.6 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4206) Prenyltrans PF00432.16 AIF84731.1 - 0.23 11.0 3.2 0.63 9.6 2.2 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Metallothio_Pro PF02069.11 AIF84732.1 - 3.5e-05 23.5 0.2 3.5e-05 23.5 0.1 1.5 1 1 1 2 2 2 1 Prokaryotic metallothionein DUF2116 PF09889.4 AIF84732.1 - 0.019 14.7 1.1 0.051 13.3 0.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NinG PF05766.7 AIF84732.1 - 0.048 13.3 0.1 0.057 13.1 0.1 1.0 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein UPF0547 PF10571.4 AIF84732.1 - 0.12 12.1 0.2 0.12 12.1 0.2 1.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Auto_anti-p27 PF06677.7 AIF84732.1 - 0.24 11.2 2.5 0.58 9.9 1.7 1.8 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) YHS PF04945.8 AIF84732.1 - 0.47 10.3 4.3 2.3 8.1 1.9 2.3 2 1 0 2 2 2 0 YHS domain DUF1628 PF07790.6 AIF84733.1 - 0.077 13.7 1.6 0.16 12.7 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) MitoNEET_N PF10660.4 AIF84735.1 - 0.0043 16.8 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus DUF1206 PF06724.6 AIF84735.1 - 0.027 14.2 0.7 0.037 13.7 0.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Pex14_N PF04695.8 AIF84735.1 - 0.081 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.1 AIF84735.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SGL PF08450.7 AIF84736.1 - 7.6e-10 38.5 0.2 0.00011 21.6 0.0 5.1 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 AIF84736.1 - 6.6e-05 22.6 0.2 0.018 14.9 0.0 3.9 4 0 0 4 4 4 1 NHL repeat Str_synth PF03088.11 AIF84736.1 - 0.016 15.2 0.0 5 7.2 0.0 4.2 4 0 0 4 4 4 0 Strictosidine synthase PepSY PF03413.14 AIF84737.1 - 0.012 16.2 0.1 0.02 15.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain E1-E2_ATPase PF00122.15 AIF84738.1 - 1.5e-56 190.9 1.4 3.3e-56 189.9 1.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AIF84738.1 - 9.6e-53 179.7 4.9 9.6e-53 179.7 3.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AIF84738.1 - 1e-20 74.7 0.0 2.2e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YHS PF04945.8 AIF84738.1 - 1.3e-08 34.5 0.2 2.5e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 YHS domain Hydrolase_3 PF08282.7 AIF84738.1 - 1.6e-07 31.2 0.4 0.0098 15.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AIF84738.1 - 0.0022 17.8 0.0 0.0088 15.9 0.0 2.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2116 PF09889.4 AIF84738.1 - 0.084 12.6 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-FCS PF06467.9 AIF84738.1 - 0.22 11.1 0.3 0.37 10.4 0.2 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HMA PF00403.21 AIF84739.1 - 1.3e-10 41.2 0.1 1.6e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain ChlI PF13541.1 AIF84739.1 - 0.075 12.5 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase DUF2963 PF11178.3 AIF84739.1 - 0.11 11.9 0.2 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) YHS PF04945.8 AIF84740.1 - 1.3e-11 44.1 0.2 1.4e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 YHS domain DEAD PF00270.24 AIF84743.1 - 7.5e-49 165.4 0.1 2.9e-47 160.3 0.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIF84743.1 - 8.7e-29 99.2 0.0 1.7e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 AIF84743.1 - 3e-05 22.6 0.0 0.076 11.4 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_30 PF13604.1 AIF84743.1 - 0.00047 19.7 0.3 0.39 10.2 0.1 2.5 2 1 0 2 2 2 2 AAA domain ResIII PF04851.10 AIF84743.1 - 0.0028 17.5 0.0 0.0072 16.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 AIF84743.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.1 AIF84743.1 - 0.063 13.0 0.4 3.9 7.2 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain CMS1 PF14617.1 AIF84743.1 - 0.088 11.8 0.1 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fer4_7 PF12838.2 AIF84744.1 - 4.4e-10 39.7 2.3 5.6e-10 39.4 1.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIF84744.1 - 4.4e-09 36.4 6.3 6.2e-09 36.0 4.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.22 AIF84744.1 - 4.7e-09 35.4 11.4 3.3e-07 29.6 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AIF84744.1 - 9.3e-08 31.9 8.8 5e-05 23.2 4.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF84744.1 - 2e-07 30.6 6.2 3.8e-07 29.7 4.4 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIF84744.1 - 2.1e-06 27.3 12.2 2e-05 24.2 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 AIF84744.1 - 2e-05 24.3 12.8 0.00012 21.8 4.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AIF84744.1 - 0.0001 22.5 4.6 0.14 12.5 0.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 AIF84744.1 - 0.00012 22.5 11.8 0.00023 21.6 1.1 2.2 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_18 PF13746.1 AIF84744.1 - 0.00019 21.8 6.8 0.032 14.6 0.5 2.3 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIF84744.1 - 0.00031 20.8 7.8 0.011 16.0 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.2 AIF84744.1 - 0.00036 20.8 12.6 0.037 14.5 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 AIF84744.1 - 0.0004 20.1 10.4 0.0018 18.0 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 AIF84744.1 - 0.0059 17.3 7.9 1 10.1 1.6 2.4 1 1 2 3 3 3 3 4Fe-4S double cluster binding domain Fer4_13 PF13370.1 AIF84744.1 - 0.061 13.7 9.5 3.3 8.1 6.6 2.2 1 1 0 1 1 1 0 4Fe-4S single cluster domain Diphthamide_syn PF01866.12 AIF84745.1 - 5.7e-69 232.7 0.1 7e-69 232.3 0.1 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Fe-ADH PF00465.14 AIF84745.1 - 0.11 11.1 0.1 0.22 10.1 0.0 1.5 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Cys_rich_CPCC PF14206.1 AIF84746.1 - 0.013 15.0 1.2 0.06 12.9 0.2 2.1 2 0 0 2 2 2 0 Cysteine-rich CPCC UbiD PF01977.11 AIF84748.1 - 3e-104 348.7 0.3 3.5e-104 348.4 0.2 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Mlf1IP PF10248.4 AIF84748.1 - 0.0018 17.9 0.2 0.0035 16.9 0.1 1.4 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein SYF2 PF08231.7 AIF84749.1 - 0.087 12.9 1.5 0.099 12.7 1.1 1.1 1 0 0 1 1 1 0 SYF2 splicing factor DUF218 PF02698.12 AIF84750.1 - 0.0067 15.9 0.0 0.009 15.5 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain IlvN PF07991.7 AIF84750.1 - 0.1 11.9 0.1 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain CARDB PF07705.6 AIF84751.1 - 0.12 12.4 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 CARDB TFIIB PF00382.14 AIF84752.1 - 6.5e-33 112.3 0.9 2e-15 56.3 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Sigma70_r4 PF04545.11 AIF84752.1 - 4.8e-06 25.7 0.0 8.5e-05 21.7 0.1 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.18 AIF84752.1 - 0.0021 17.6 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_AsnC-type PF13404.1 AIF84752.1 - 0.0039 16.6 3.1 0.077 12.5 0.1 3.1 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain Cyclin_C PF02984.14 AIF84752.1 - 0.022 14.7 0.0 5.7 6.8 0.0 2.3 1 1 1 2 2 2 0 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.1 AIF84752.1 - 0.042 13.0 0.3 1.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.15 AIF84752.1 - 0.049 13.7 0.3 13 5.9 0.0 3.3 1 1 2 3 3 3 0 Transcriptional regulator Sigma70_r4_2 PF08281.7 AIF84752.1 - 0.15 11.5 0.1 0.15 11.5 0.1 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 ABM PF03992.11 AIF84753.1 - 8.5e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4286 PF14114.1 AIF84753.1 - 0.0062 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) DUF4149 PF13664.1 AIF84753.1 - 0.051 13.6 2.1 0.092 12.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) HxlR PF01638.12 AIF84754.1 - 3e-25 87.6 0.1 3.8e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix EutH PF04346.7 AIF84755.1 - 0.0076 15.2 2.2 0.009 15.0 1.5 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH CopD PF05425.8 AIF84755.1 - 0.0089 16.2 5.0 0.0089 16.2 3.5 1.9 1 1 1 2 2 2 1 Copper resistance protein D LEA_2 PF03168.8 AIF84756.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein CopD PF05425.8 AIF84757.1 - 4.1e-14 52.6 6.3 4.1e-14 52.6 4.3 1.7 2 0 0 2 2 2 1 Copper resistance protein D DUF4149 PF13664.1 AIF84757.1 - 0.00065 19.7 0.5 0.00065 19.7 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1035 PF06281.7 AIF84757.1 - 0.01 15.5 0.5 0.01 15.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) DUF2269 PF10027.4 AIF84757.1 - 0.03 14.0 8.9 0.043 13.5 6.2 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF989 PF06181.6 AIF84757.1 - 0.08 12.0 0.3 0.08 12.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF989) DUF350 PF03994.9 AIF84757.1 - 0.41 10.4 0.1 0.41 10.4 0.0 3.3 4 0 0 4 4 4 0 Domain of Unknown Function (DUF350) UPF0093 PF03653.8 AIF84757.1 - 0.69 9.8 4.0 0.11 12.4 0.4 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) RTC PF01137.16 AIF84758.1 - 4.6e-70 234.9 0.1 5.3e-70 234.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 AIF84758.1 - 4.2e-13 49.1 0.1 8.3e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Bac_luciferase PF00296.15 AIF84759.1 - 1.2e-55 188.8 0.0 1.3e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase CTP_transf_2 PF01467.21 AIF84760.1 - 2.7e-20 73.0 0.3 6.7e-20 71.7 0.1 1.7 1 1 1 2 2 2 1 Cytidylyltransferase Citrate_ly_lig PF08218.6 AIF84760.1 - 0.076 12.4 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain Prominin PF05478.6 AIF84762.1 - 0.033 11.7 0.0 0.041 11.4 0.0 1.0 1 0 0 1 1 1 0 Prominin Asparaginase PF00710.15 AIF84763.1 - 8.2e-87 290.9 0.5 1.1e-86 290.6 0.3 1.1 1 0 0 1 1 1 1 Asparaginase GatB_N PF02934.10 AIF84764.1 - 2.1e-71 240.1 0.0 2.8e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AIF84764.1 - 2.1e-20 72.9 2.5 2.1e-20 72.9 1.7 2.0 2 0 0 2 2 2 1 GatB domain GAD PF02938.9 AIF84764.1 - 1e-07 31.9 0.0 3.4e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 GAD domain YqeY PF09424.5 AIF84764.1 - 0.00096 19.0 0.8 0.00096 19.0 0.6 2.0 2 0 0 2 2 2 1 Yqey-like protein Hist_deacetyl PF00850.14 AIF84764.1 - 0.16 11.2 0.1 0.55 9.4 0.0 1.8 2 0 0 2 2 2 0 Histone deacetylase domain DUF310 PF03750.8 AIF84765.1 - 0.073 13.2 0.1 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF310) Abi PF02517.11 AIF84766.1 - 3.4e-06 27.1 7.1 3.4e-06 27.1 4.9 1.8 2 1 0 2 2 2 1 CAAX protease self-immunity Neocarzinostat PF00960.13 AIF84766.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Neocarzinostatin family HTH_27 PF13463.1 AIF84767.1 - 0.00044 20.5 0.1 0.00099 19.3 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_45 PF14947.1 AIF84767.1 - 0.00046 19.9 0.0 0.0025 17.6 0.0 1.9 2 1 0 2 2 2 1 Winged helix-turn-helix HTH_34 PF13601.1 AIF84767.1 - 0.0057 16.6 0.0 0.037 14.0 0.0 2.1 2 1 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.14 AIF84767.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AIF84767.1 - 0.016 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 MarR family MarR PF01047.17 AIF84767.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 MarR family Rio2_N PF09202.6 AIF84767.1 - 0.046 13.7 0.0 0.099 12.7 0.0 1.6 1 1 0 1 1 1 0 Rio2, N-terminal HTH_24 PF13412.1 AIF84767.1 - 0.083 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding zf-ZPR1 PF03367.8 AIF84768.1 - 0.078 12.1 0.2 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain UPF0180 PF03698.8 AIF84768.1 - 0.11 12.3 0.2 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0180) NurA PF09376.5 AIF84769.1 - 3e-09 36.7 0.4 9.1e-08 31.8 0.3 2.1 1 1 0 1 1 1 1 NurA domain AAA_10 PF12846.2 AIF84770.1 - 1.8e-15 57.2 0.2 3.4e-07 30.0 0.0 2.2 1 1 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 AIF84770.1 - 6.1e-08 32.7 0.0 2.3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF87 AAA_17 PF13207.1 AIF84770.1 - 0.0025 18.6 0.0 0.23 12.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 AIF84770.1 - 0.021 14.5 0.9 0.073 12.7 0.1 2.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 AIF84770.1 - 0.042 13.9 0.0 1.2 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain CbiA PF01656.18 AIF84770.1 - 0.045 13.1 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 AIF84770.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 AIF84770.1 - 0.065 13.1 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 AIF84770.1 - 0.092 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 P-II PF00543.17 AIF84771.1 - 3.3e-22 78.8 0.8 4e-22 78.6 0.5 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Amido_AtzD_TrzD PF09663.5 AIF84771.1 - 0.0055 15.3 2.4 0.0074 14.9 1.7 1.2 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) LTD PF00932.14 AIF84772.1 - 8.2e-10 38.7 0.7 2.1e-09 37.4 0.5 1.7 1 0 0 1 1 1 1 Lamin Tail Domain SNase PF00565.12 AIF84772.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Corona_6B_7B PF03262.8 AIF84772.1 - 0.028 13.6 0.2 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein DUF1469 PF07332.6 AIF84773.1 - 0.00055 19.6 10.9 0.00057 19.6 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) DUF2910 PF11139.3 AIF84773.1 - 0.011 14.9 5.0 0.012 14.7 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) DUF998 PF06197.8 AIF84773.1 - 0.046 13.0 5.8 0.054 12.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Chromate_transp PF02417.10 AIF84773.1 - 0.092 12.3 5.2 0.098 12.2 3.6 1.0 1 0 0 1 1 1 0 Chromate transporter NfeD PF01957.13 AIF84773.1 - 0.26 11.4 5.3 0.29 11.2 3.7 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DctQ PF04290.7 AIF84773.1 - 0.55 9.9 6.4 0.71 9.6 4.4 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3366 PF11846.3 AIF84773.1 - 0.74 9.6 3.4 0.84 9.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) DUF4175 PF13779.1 AIF84773.1 - 1.2 6.7 4.8 1.2 6.7 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RSN1_TM PF13967.1 AIF84773.1 - 1.8 8.1 4.3 1.6 8.2 0.3 2.0 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport Trp_oprn_chp PF09534.5 AIF84773.1 - 2.1 7.9 10.4 2.5 7.6 7.2 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1206 PF06724.6 AIF84773.1 - 4.7 7.0 9.8 73 3.2 6.8 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) Glycos_transf_4 PF00953.16 AIF84774.1 - 2.7e-26 92.2 16.7 2.7e-26 92.2 11.6 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 DEAD PF00270.24 AIF84775.1 - 8e-26 90.5 0.0 1.6e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIF84775.1 - 1.2e-10 41.0 0.0 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 AIF84775.1 - 1.4e-09 37.9 2.9 8.7e-09 35.4 0.4 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain ResIII PF04851.10 AIF84775.1 - 6e-06 26.2 0.0 0.00028 20.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HHH PF00633.18 AIF84775.1 - 0.0002 20.8 2.1 0.19 11.5 0.0 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_2 PF12826.2 AIF84775.1 - 0.0041 16.9 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_19 PF13245.1 AIF84775.1 - 0.0053 16.4 4.4 0.041 13.6 0.3 3.3 3 0 0 3 3 3 1 Part of AAA domain DUF4157 PF13699.1 AIF84776.1 - 0.0047 17.0 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4157) Peptidase_MA_2 PF13485.1 AIF84776.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.4 1 1 0 1 1 1 0 Peptidase MA superfamily MCM PF00493.18 AIF84777.1 - 3.8e-124 413.8 0.1 5e-124 413.4 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AIF84777.1 - 3e-19 69.6 0.2 8.5e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AIF84777.1 - 9.8e-07 28.1 0.1 0.00023 20.3 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AIF84777.1 - 1.7e-06 27.8 0.0 9e-06 25.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AIF84777.1 - 0.0016 18.0 0.0 0.0061 16.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.5 AIF84777.1 - 0.13 12.2 0.4 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Sld5 PF05916.6 AIF84778.1 - 4.3e-05 23.7 0.0 7.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DNA_pol3_delta2 PF13177.1 AIF84779.1 - 8.6e-17 61.2 0.0 8.3e-16 58.0 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AIF84779.1 - 9.1e-14 51.7 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AIF84779.1 - 3.4e-09 35.9 0.0 7.1e-07 28.2 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 AIF84779.1 - 1.5e-08 34.4 0.1 6.8e-08 32.3 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 AIF84779.1 - 1.3e-06 27.6 0.1 2.9e-06 26.4 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AIF84779.1 - 1.5e-06 28.1 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIF84779.1 - 2.2e-06 27.8 0.2 4.6e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 AIF84779.1 - 8.5e-05 22.1 0.2 0.088 12.3 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_16 PF13191.1 AIF84779.1 - 0.00022 21.2 0.1 0.04 13.9 0.0 2.5 2 1 0 3 3 2 1 AAA ATPase domain AAA_10 PF12846.2 AIF84779.1 - 0.0003 20.3 1.6 0.14 11.6 0.0 2.6 1 1 0 3 3 3 2 AAA-like domain Arch_ATPase PF01637.13 AIF84779.1 - 0.00096 18.9 0.0 0.068 12.8 0.0 2.2 1 1 1 2 2 2 2 Archaeal ATPase ArgK PF03308.11 AIF84779.1 - 0.0015 17.3 0.2 0.0046 15.7 0.1 1.9 1 1 0 1 1 1 1 ArgK protein Mg_chelatase PF01078.16 AIF84779.1 - 0.0026 16.9 0.0 0.56 9.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AIF84779.1 - 0.0028 17.3 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 AIF84779.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 2 0 0 2 2 1 1 DNA polymerase III, delta subunit NB-ARC PF00931.17 AIF84779.1 - 0.0074 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ResIII PF04851.10 AIF84779.1 - 0.0091 15.8 0.0 0.33 10.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_2 PF07724.9 AIF84779.1 - 0.012 15.5 0.0 0.035 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 AIF84779.1 - 0.015 14.5 0.0 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.9 AIF84779.1 - 0.018 14.7 0.2 0.064 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 AIF84779.1 - 0.021 14.2 0.1 0.34 10.3 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 AIF84779.1 - 0.026 14.8 0.0 0.099 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIF84779.1 - 0.026 14.0 0.2 0.093 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AIF84779.1 - 0.039 13.6 0.6 1.8 8.2 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_17 PF13207.1 AIF84779.1 - 0.045 14.5 0.0 0.11 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AIF84779.1 - 0.05 12.5 0.1 0.2 10.5 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 AIF84779.1 - 0.057 12.1 0.2 0.38 9.4 0.0 2.2 2 1 0 3 3 3 0 TIP49 C-terminus AAA_25 PF13481.1 AIF84779.1 - 0.088 12.2 0.1 0.27 10.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 AIF84779.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 AIF84779.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2296 PF10058.4 AIF84780.1 - 0.00069 19.3 0.3 0.0015 18.1 0.2 1.6 1 1 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zinc_ribbon_5 PF13719.1 AIF84780.1 - 0.0017 17.9 0.5 0.28 10.8 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIF84780.1 - 0.0021 17.7 0.4 0.44 10.2 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AIF84780.1 - 0.012 15.2 0.1 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain tRNA-synt_1f PF01921.13 AIF84780.1 - 0.016 13.8 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) C1_1 PF00130.17 AIF84780.1 - 0.017 14.8 0.3 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 AIF84780.1 - 0.03 14.4 0.1 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-ribbon_3 PF13248.1 AIF84780.1 - 0.045 12.9 0.8 0.6 9.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 AIF84780.1 - 0.071 12.7 1.4 4 7.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) TF_Zn_Ribbon PF08271.7 AIF84780.1 - 0.1 11.9 6.0 3 7.2 0.0 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C2H2 PF00096.21 AIF84780.1 - 0.1 12.9 0.9 20 5.7 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type CpXC PF14353.1 AIF84780.1 - 0.11 12.4 2.2 1.2 9.1 0.1 2.3 1 1 1 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.1 AIF84780.1 - 0.13 12.2 1.3 7.5 6.6 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AIF84780.1 - 0.13 12.6 0.4 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.14 AIF84780.1 - 0.13 11.9 0.6 0.27 10.9 0.3 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 AIF84780.1 - 0.14 11.8 1.8 8.5 6.1 0.0 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.7 AIF84780.1 - 0.16 12.0 1.1 12 6.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-H2C2_2 PF13465.1 AIF84780.1 - 0.19 12.0 4.3 3.3 8.1 0.3 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 AIF84780.1 - 0.23 11.4 3.3 1.4 8.9 2.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Rubredoxin PF00301.15 AIF84780.1 - 0.3 10.9 2.2 2.3 8.1 0.0 2.6 3 0 0 3 3 3 0 Rubredoxin DUF1610 PF07754.6 AIF84780.1 - 0.42 10.7 0.1 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Pirin PF02678.11 AIF84781.1 - 4.1e-38 129.5 0.2 1.2e-37 128.0 0.1 1.8 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 AIF84781.1 - 1.7e-34 118.0 0.0 9.2e-33 112.4 0.0 2.9 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 AIF84781.1 - 7.7e-09 34.9 2.6 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 AIF84781.1 - 0.0028 16.9 0.3 0.16 11.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 AIF84781.1 - 0.1 12.3 0.0 9.1 5.9 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain Patatin PF01734.17 AIF84782.1 - 2.8e-26 92.7 0.0 4.4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3734 PF12536.3 AIF84782.1 - 1.1e-05 25.4 0.8 4e-05 23.7 0.5 1.9 1 1 0 1 1 1 1 Patatin phospholipase ArdA PF07275.6 AIF84782.1 - 0.031 14.5 0.2 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 Antirestriction protein (ArdA) NYD-SP28_assoc PF14775.1 AIF84782.1 - 0.05 13.3 0.6 2.7 7.7 0.0 2.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain Ribosomal_S8 PF00410.14 AIF84782.1 - 0.05 13.4 0.3 0.088 12.6 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S8 PTPA PF03095.10 AIF84782.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF1469 PF07332.6 AIF84783.1 - 0.023 14.4 2.8 0.023 14.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF202 PF02656.10 AIF84783.1 - 0.12 12.6 0.1 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF1049 PF06305.6 AIF84783.1 - 2.3 7.7 7.8 0.99 8.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) FTR1 PF03239.9 AIF84784.1 - 1.9e-17 63.1 23.7 2.7e-16 59.4 13.9 3.3 2 1 0 2 2 2 1 Iron permease FTR1 family Lactonase PF10282.4 AIF84785.1 - 5e-09 35.6 1.1 2.2e-06 26.9 0.2 2.2 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller NHL PF01436.16 AIF84785.1 - 9.5e-08 31.6 25.3 0.1 12.5 0.1 8.3 8 3 2 10 10 10 5 NHL repeat Cytochrom_D1 PF02239.11 AIF84785.1 - 1.1e-05 23.8 2.1 0.002 16.5 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain SGL PF08450.7 AIF84785.1 - 0.00011 21.6 3.3 0.0017 17.8 2.3 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 AIF84785.1 - 0.0019 18.1 13.0 1.3 9.0 0.1 5.2 2 1 4 6 6 6 3 Arylesterase Cyd_oper_YbgE PF09600.5 AIF84785.1 - 0.065 13.4 0.4 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) He_PIG PF05345.7 AIF84785.1 - 0.28 11.2 1.8 20 5.2 0.0 3.4 3 0 0 3 3 3 0 Putative Ig domain DUF4340 PF14238.1 AIF84785.1 - 0.34 10.6 4.4 4.9 6.7 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4340) PBP5_C PF07943.8 AIF84785.1 - 1.1 9.2 6.0 24 4.9 0.3 4.2 5 1 0 5 5 5 0 Penicillin-binding protein 5, C-terminal domain Ribosomal_S7 PF00177.16 AIF84787.1 - 5.5e-38 129.8 1.9 8.4e-38 129.2 1.3 1.3 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.20 AIF84788.1 - 1.4e-39 134.2 0.2 1.6e-39 134.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KH_2 PF07650.12 AIF84789.1 - 1.6e-22 78.8 1.6 8.4e-15 54.0 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 AIF84789.1 - 6.3e-11 41.9 2.7 6.9e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 NusA-like KH domain KH_4 PF13083.1 AIF84789.1 - 7.7e-11 41.4 1.2 0.00027 20.5 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_1 PF00013.24 AIF84789.1 - 3.8e-09 36.0 0.5 3e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 AIF84789.1 - 0.013 15.1 0.3 0.013 15.1 0.2 2.5 3 0 0 3 3 3 0 KH domain DUF3979 PF13141.1 AIF84789.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Ribosomal_L7Ae PF01248.21 AIF84790.1 - 1.4e-10 40.5 1.6 1.6e-10 40.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PYNP_C PF07831.8 AIF84790.1 - 0.027 13.8 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain RNA_pol_Rpb1_5 PF04998.12 AIF84791.1 - 2.6e-86 289.3 0.8 4.4e-86 288.5 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AIF84791.1 - 1.5e-83 280.9 0.4 1.6e-81 274.1 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AIF84791.1 - 3.9e-69 231.8 0.0 1e-68 230.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AIF84791.1 - 7.6e-32 110.2 0.0 1.7e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AIF84791.1 - 1.3e-24 86.0 0.0 3.1e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TniQ PF06527.6 AIF84791.1 - 0.014 15.6 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 TniQ NAC PF01849.13 AIF84791.1 - 0.028 13.9 0.1 0.089 12.3 0.0 1.8 1 0 0 1 1 1 0 NAC domain DUF164 PF02591.10 AIF84791.1 - 0.71 9.7 2.6 7.1 6.5 0.2 3.0 2 1 1 3 3 3 0 Putative zinc ribbon domain RNA_pol_Rpb2_6 PF00562.23 AIF84792.1 - 8.6e-120 400.0 0.0 1.4e-119 399.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AIF84792.1 - 1.3e-53 180.9 0.0 2e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AIF84792.1 - 2.2e-30 104.7 0.1 4.9e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 AIF84792.1 - 2.4e-27 94.4 0.0 4.5e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 AIF84792.1 - 8.8e-22 77.4 0.0 1.8e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 AIF84792.1 - 1.6e-14 53.4 0.1 5.7e-14 51.6 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 AIF84792.1 - 1.6e-13 50.4 0.3 3.5e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FYVE PF01363.16 AIF84792.1 - 0.025 14.4 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 AIF84792.1 - 0.048 13.4 0.4 0.098 12.4 0.3 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF2318 PF10080.4 AIF84792.1 - 0.12 12.1 0.4 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.6 AIF84792.1 - 0.2 11.3 1.3 0.6 9.8 0.9 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CAF1-p150_N PF15557.1 AIF84792.1 - 0.27 10.5 0.0 0.47 9.7 0.0 1.3 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA RNA_pol_Rpb5_C PF01191.14 AIF84793.1 - 2.6e-28 97.3 0.7 3e-28 97.1 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain CDC48_N PF02359.13 AIF84793.1 - 0.058 13.3 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Molydop_binding PF01568.16 AIF84793.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain A2M_N PF01835.14 AIF84794.1 - 5.1e-06 26.6 0.1 1.1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 MG2 domain DUF4369 PF14289.1 AIF84794.1 - 0.012 15.6 2.9 0.028 14.4 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4369) Big_3 PF07523.7 AIF84794.1 - 0.026 14.6 0.3 0.026 14.6 0.2 3.4 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Big_3_4 PF13754.1 AIF84794.1 - 5.3 7.4 15.3 1.9 8.8 0.3 3.8 3 2 0 3 3 3 0 Bacterial Ig-like domain (group 3) NIF3 PF01784.13 AIF84795.1 - 4.3e-20 72.3 1.4 4.6e-19 68.9 0.9 1.9 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ADH_zinc_N PF00107.21 AIF84795.1 - 0.092 12.2 0.3 0.31 10.5 0.2 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Wyosine_form PF08608.7 AIF84796.1 - 8e-19 67.5 0.0 2.5e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 AIF84796.1 - 5e-17 62.5 0.1 2.3e-16 60.4 0.1 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 AIF84796.1 - 0.0038 17.2 0.1 0.027 14.4 0.1 2.3 1 1 0 1 1 1 1 4Fe-4S single cluster domain Ham1p_like PF01725.11 AIF84797.1 - 1.8e-50 170.9 0.1 2.1e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family APH PF01636.18 AIF84798.1 - 1.8e-10 40.9 1.2 8.8e-07 28.8 0.1 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 AIF84798.1 - 1.3e-08 34.2 0.0 4e-08 32.7 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Kdo PF06293.9 AIF84798.1 - 3.2e-07 29.6 0.0 6.7e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AIF84798.1 - 3.9e-07 29.5 0.0 6.9e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 AIF84798.1 - 6.8e-05 22.0 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 AIF84798.1 - 0.00011 21.8 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 AIF84798.1 - 0.00025 20.1 0.1 0.00084 18.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like EcKinase PF02958.15 AIF84798.1 - 0.00037 19.7 0.0 0.00064 18.9 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.6 AIF84798.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Fructosamin_kin PF03881.9 AIF84798.1 - 0.045 12.7 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase bPH_3 PF14470.1 AIF84799.1 - 7.8e-06 26.0 0.1 1.4e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 Bacterial PH domain GRAM PF02893.15 AIF84799.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Peptidase_M22 PF00814.20 AIF84800.1 - 3.7e-77 259.4 0.0 4.3e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family FGGY_N PF00370.16 AIF84800.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain MMR_HSR1_C PF08438.5 AIF84801.1 - 5.6e-32 110.2 0.1 9.5e-32 109.4 0.1 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AIF84801.1 - 1.5e-18 66.7 0.0 3.7e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 AIF84801.1 - 1.7e-13 50.2 0.2 5e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 AIF84801.1 - 3.7e-07 29.5 0.1 3.1e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.1 AIF84801.1 - 0.0096 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain YchF-GTPase_C PF06071.8 AIF84801.1 - 0.021 14.6 0.0 0.085 12.6 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF933) DUF2132 PF09905.4 AIF84801.1 - 0.065 13.2 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) ThiS PF02597.15 AIF84801.1 - 0.11 12.9 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 ThiS family Cupin_5 PF06172.6 AIF84802.1 - 3.8e-48 162.9 0.0 4.6e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) QueC PF06508.8 AIF84803.1 - 6.2e-50 169.3 0.1 7.1e-50 169.1 0.1 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 AIF84803.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 AIF84803.1 - 0.0082 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ApbA_C PF08546.6 AIF84803.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Fer4_14 PF13394.1 AIF84804.1 - 2.6e-18 66.1 0.1 4e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 AIF84804.1 - 2.5e-14 53.7 0.2 3.3e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 AIF84804.1 - 3.4e-14 53.1 0.1 5.5e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain GTP_cyclohydroI PF01227.17 AIF84805.1 - 5.8e-61 204.9 0.1 6.6e-61 204.7 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AIF84805.1 - 0.0033 17.3 0.0 0.0074 16.2 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein PepSY PF03413.14 AIF84806.1 - 6.4e-06 26.7 0.9 2.5e-05 24.8 0.6 1.9 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain AAA PF00004.24 AIF84808.1 - 7.9e-16 58.4 0.1 5.4e-15 55.7 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AIF84808.1 - 8.2e-09 34.6 0.0 0.00073 18.3 0.0 2.4 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 AIF84808.1 - 3e-07 30.3 0.0 6.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIF84808.1 - 7.7e-07 29.2 0.1 0.00094 19.2 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 AIF84808.1 - 1.3e-06 29.1 0.0 3.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIF84808.1 - 3.8e-06 27.0 0.0 0.00026 21.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIF84808.1 - 6.2e-06 25.9 0.0 1.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AIF84808.1 - 0.00031 19.8 0.0 0.00066 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AIF84808.1 - 0.00035 20.2 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AIF84808.1 - 0.00087 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 AIF84808.1 - 0.00088 18.9 0.0 0.15 11.7 0.0 2.5 1 1 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 AIF84808.1 - 0.00093 19.5 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AIF84808.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 AIF84808.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIF84808.1 - 0.0014 18.5 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 AIF84808.1 - 0.0034 16.5 0.0 0.0081 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 AIF84808.1 - 0.0059 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AIF84808.1 - 0.0074 15.4 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 AIF84808.1 - 0.0094 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 AIF84808.1 - 0.0097 16.0 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 AIF84808.1 - 0.01 15.5 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 NTPase TIP49 PF06068.8 AIF84808.1 - 0.016 13.9 0.0 0.031 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_29 PF13555.1 AIF84808.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.6 AIF84808.1 - 0.029 13.9 0.0 0.093 12.3 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AIF84808.1 - 0.037 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 AIF84808.1 - 0.039 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 AIF84808.1 - 0.055 12.3 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 AIF84808.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 AIF84808.1 - 0.086 12.7 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase Miro PF08477.8 AIF84808.1 - 0.1 13.1 0.0 0.41 11.1 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein SRP54 PF00448.17 AIF84808.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.1 AIF84808.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prok-RING_1 PF14446.1 AIF84809.1 - 0.082 12.6 0.1 0.082 12.6 0.1 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DUF2175 PF09943.4 AIF84809.1 - 0.096 12.7 0.2 0.096 12.7 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2911 PF11138.3 AIF84809.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Subtilosin_A PF11420.3 AIF84809.1 - 0.12 12.3 2.2 0.12 12.3 1.5 2.1 2 0 0 2 2 2 0 Bacteriocin subtilosin A ProRS-C_1 PF09180.6 AIF84809.1 - 0.35 10.8 7.2 5 7.1 0.1 2.6 2 1 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal ATG16 PF08614.6 AIF84810.1 - 0.048 13.4 0.4 0.049 13.4 0.3 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Vps5 PF09325.5 AIF84810.1 - 0.055 12.7 0.1 0.064 12.4 0.1 1.0 1 0 0 1 1 1 0 Vps5 C terminal like DUF4618 PF15397.1 AIF84810.1 - 0.13 11.5 0.8 0.16 11.3 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) GYD PF08734.6 AIF84811.1 - 0.085 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 GYD domain ADH_zinc_N PF00107.21 AIF84812.1 - 1.2e-32 112.2 0.1 2.1e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIF84812.1 - 4.4e-26 90.7 0.1 8.4e-26 89.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIF84812.1 - 1.6e-15 58.0 0.1 3.5e-15 57.0 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 AIF84812.1 - 0.00076 18.9 0.1 0.0013 18.2 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase ACP_syn_III_C PF08541.5 AIF84812.1 - 0.017 15.1 0.1 0.049 13.6 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cpn10 PF00166.16 AIF84812.1 - 0.064 13.1 0.9 0.25 11.3 0.4 2.2 2 1 0 2 2 2 0 Chaperonin 10 Kd subunit Eno-Rase_NADH_b PF12242.3 AIF84812.1 - 0.071 12.9 1.5 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Carboxyl_trans PF01039.17 AIF84813.1 - 4.7e-190 632.1 0.3 5.4e-190 631.9 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 AIF84813.1 - 1.7e-06 27.4 0.0 5.4e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) CPSase_L_D2 PF02786.12 AIF84814.1 - 1.8e-74 249.6 0.0 2.7e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AIF84814.1 - 1.2e-44 150.8 0.1 2.3e-43 146.7 0.1 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AIF84814.1 - 2.3e-35 120.7 0.0 4.9e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 AIF84814.1 - 2.5e-18 66.4 0.1 4.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AIF84814.1 - 8.6e-15 54.2 0.0 2.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 AIF84814.1 - 1.8e-10 40.5 0.0 2.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 AIF84814.1 - 3e-07 30.0 0.0 1.1e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 AIF84814.1 - 7.6e-07 28.6 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AIF84814.1 - 3.4e-05 23.7 0.0 0.00026 20.9 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 AIF84814.1 - 0.057 12.1 0.0 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 YheC/D like ATP-grasp Biotin_lipoyl PF00364.17 AIF84815.1 - 2.4e-16 59.1 5.1 3.7e-16 58.5 2.4 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 AIF84815.1 - 1.2e-14 53.6 2.6 1.1e-10 41.0 0.2 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 AIF84815.1 - 6.8e-05 22.3 2.4 0.0023 17.3 0.2 2.1 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 AIF84815.1 - 0.00013 21.1 2.5 0.1 11.7 0.1 2.5 2 1 1 3 3 3 2 HlyD family secretion protein GCV_H PF01597.14 AIF84815.1 - 0.0045 16.6 0.8 0.01 15.5 0.3 1.8 2 0 0 2 2 2 1 Glycine cleavage H-protein HlyD_3 PF13437.1 AIF84815.1 - 0.0045 17.2 1.2 3.8 7.8 0.1 2.8 3 1 0 3 3 3 2 HlyD family secretion protein DUF2118 PF09891.4 AIF84815.1 - 0.015 14.9 0.8 0.13 11.9 0.2 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Activator-TraM PF11657.3 AIF84815.1 - 0.041 13.3 0.6 0.62 9.5 0.0 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM PYNP_C PF07831.8 AIF84815.1 - 0.076 12.4 0.5 0.76 9.2 0.1 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain PASTA PF03793.14 AIF84815.1 - 0.091 12.4 0.2 0.28 10.8 0.1 2.0 2 0 0 2 2 2 0 PASTA domain Fer2_4 PF13510.1 AIF84815.1 - 0.13 12.0 0.1 0.36 10.6 0.0 1.9 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Lactamase_B_2 PF12706.2 AIF84817.1 - 6.1e-17 61.7 0.1 7.5e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AIF84817.1 - 2.3e-06 27.4 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AhpC-TSA PF00578.16 AIF84818.1 - 4.6e-38 129.6 0.0 5.8e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIF84818.1 - 1.4e-25 89.5 0.0 1.6e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 AIF84818.1 - 0.00013 21.6 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Aminotran_5 PF00266.14 AIF84819.1 - 1e-94 317.3 0.0 1.2e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AIF84819.1 - 8.5e-07 28.3 0.0 1.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AIF84819.1 - 0.00041 19.5 0.2 0.00074 18.6 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 AIF84819.1 - 0.054 11.7 0.0 0.08 11.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme QueC PF06508.8 AIF84820.1 - 6.1e-10 38.7 0.0 9.3e-09 34.8 0.0 2.3 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 AIF84820.1 - 1.6e-09 37.0 0.0 3.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 AIF84820.1 - 1.7e-09 37.5 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 AIF84820.1 - 1.5e-08 33.5 0.0 6e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.15 AIF84820.1 - 6.7e-05 22.4 0.0 0.00035 20.1 0.0 2.1 1 1 0 2 2 2 1 PP-loop family ThiI PF02568.9 AIF84820.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.5 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 AIF84820.1 - 0.0033 16.5 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.14 AIF84820.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HTH_CodY PF08222.6 AIF84820.1 - 0.05 12.9 0.4 5.2 6.4 0.1 2.4 2 0 0 2 2 2 0 CodY helix-turn-helix domain Phosphodiest PF01663.17 AIF84820.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF111 PF01969.12 AIF84821.1 - 4.1e-110 368.1 2.5 4.7e-110 368.0 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 HypA PF01155.14 AIF84822.1 - 0.079 12.6 0.1 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family RdRP_4 PF02123.11 AIF84822.1 - 0.083 11.6 0.0 0.095 11.4 0.0 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase GvpG PF05120.7 AIF84824.1 - 0.044 13.5 0.9 0.062 13.1 0.6 1.3 1 0 0 1 1 1 0 Gas vesicle protein G CbtA PF09490.5 AIF84825.1 - 0.021 14.1 22.4 0.16 11.2 15.5 2.1 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Yip1 PF04893.12 AIF84825.1 - 0.32 10.4 20.8 0.68 9.4 5.0 2.4 1 1 0 2 2 2 0 Yip1 domain ATG22 PF11700.3 AIF84825.1 - 7.3 4.9 11.8 4 5.8 1.2 2.7 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 AIF84826.1 - 7.5e-36 123.5 42.9 6.1e-28 97.5 19.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AIF84826.1 - 1.2e-05 23.9 26.7 0.0042 15.5 6.8 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 AIF84826.1 - 8.4e-05 21.3 9.0 8.4e-05 21.3 6.2 2.8 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 AIF84826.1 - 0.00016 21.3 2.0 0.00016 21.3 1.4 3.2 3 0 0 3 3 3 1 MFS_1 like family MFS_3 PF05977.8 AIF84826.1 - 0.0013 16.9 16.8 0.025 12.7 2.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector HTH_CodY PF08222.6 AIF84826.1 - 0.088 12.1 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 CodY helix-turn-helix domain Chrome_Resist PF09828.4 AIF84827.1 - 7.9e-52 175.0 0.1 9e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 Chromate resistance exported protein DUF2154 PF09922.4 AIF84828.1 - 0.019 14.6 0.5 0.045 13.4 0.2 1.6 2 0 0 2 2 2 0 Cell wall-active antibiotics response protein (DUF2154) COX2 PF00116.15 AIF84828.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain DUF508 PF04370.7 AIF84828.1 - 0.78 9.3 3.4 0.25 10.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Toxin_9 PF02819.10 AIF84829.1 - 0.0027 17.7 4.1 0.0048 16.9 2.8 1.4 1 0 0 1 1 1 1 Spider toxin TruB_N PF01509.13 AIF84830.1 - 9.1e-24 84.3 0.8 5.3e-20 72.0 0.6 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.7 AIF84830.1 - 1.1e-15 57.3 0.1 2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 DKCLD (NUC011) domain PUA PF01472.15 AIF84830.1 - 2.7e-14 52.6 0.5 4.6e-14 51.9 0.4 1.4 1 0 0 1 1 1 1 PUA domain Cytidylate_kin2 PF13189.1 AIF84831.1 - 2.7e-16 59.9 0.0 3.4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 AIF84831.1 - 1.4e-12 48.0 0.0 1.8e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIF84831.1 - 9.1e-09 36.1 0.1 1.9e-08 35.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIF84831.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AIF84831.1 - 0.0036 17.2 0.2 0.015 15.2 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 AIF84831.1 - 0.0055 16.9 0.2 0.0091 16.1 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 AIF84831.1 - 0.0067 15.6 0.0 0.013 14.7 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 RNA_helicase PF00910.17 AIF84831.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 AIF84831.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain ADK PF00406.17 AIF84831.1 - 0.034 14.0 0.1 0.099 12.5 0.0 1.7 2 0 0 2 2 2 0 Adenylate kinase SKI PF01202.17 AIF84831.1 - 0.037 13.8 1.4 0.48 10.2 0.9 2.4 1 1 0 1 1 1 0 Shikimate kinase AAA_22 PF13401.1 AIF84831.1 - 0.051 13.7 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF106 PF01956.11 AIF84832.1 - 8.3e-10 38.4 7.7 5e-09 35.9 5.3 1.9 1 1 0 1 1 1 1 Integral membrane protein DUF106 RSN1_TM PF13967.1 AIF84832.1 - 0.0047 16.4 0.1 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 Late exocytosis, associated with Golgi transport AAA_18 PF13238.1 AIF84833.1 - 9.4e-13 48.5 0.0 1.3e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIF84833.1 - 1.5e-06 29.0 0.0 2.1e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 AIF84833.1 - 5e-06 26.0 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 AIF84833.1 - 2.2e-05 24.4 0.2 4.5e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AIF84833.1 - 0.00012 22.0 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIF84833.1 - 0.00024 21.2 0.1 0.00045 20.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AIF84833.1 - 0.00057 19.5 0.2 0.002 17.8 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain KTI12 PF08433.5 AIF84833.1 - 0.00081 18.6 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 AIF84833.1 - 0.0032 17.1 1.6 0.0087 15.7 1.1 1.7 1 1 0 1 1 1 1 NTPase AAA_30 PF13604.1 AIF84833.1 - 0.005 16.4 0.4 0.01 15.4 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AIF84833.1 - 0.0075 15.9 0.2 0.018 14.7 0.1 1.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 AIF84833.1 - 0.0078 15.2 0.0 0.0083 15.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 AIF84833.1 - 0.0086 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase cobW PF02492.14 AIF84833.1 - 0.0097 15.3 0.0 0.067 12.6 0.1 2.0 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 AIF84833.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 AIF84833.1 - 0.016 14.9 0.5 0.036 13.7 0.4 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 AIF84833.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 AIF84833.1 - 0.025 14.1 0.2 0.046 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 AIF84833.1 - 0.028 14.2 0.9 0.11 12.2 0.6 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 AIF84833.1 - 0.035 13.6 0.3 0.41 10.1 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 AIF84833.1 - 0.037 13.1 0.7 0.12 11.4 0.5 1.8 1 1 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 AIF84833.1 - 0.042 13.7 0.1 0.077 12.9 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 AIF84833.1 - 0.047 12.8 0.1 0.14 11.2 0.0 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AIF84833.1 - 0.073 12.9 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AIF84833.1 - 0.079 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 AIF84833.1 - 0.12 12.9 0.1 0.2 12.1 0.1 1.4 1 1 0 1 1 1 0 Miro-like protein AAA_11 PF13086.1 AIF84833.1 - 0.16 11.5 0.9 0.36 10.3 0.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AIF84833.1 - 0.22 10.9 1.8 1.9 7.8 1.3 2.2 1 1 0 1 1 1 0 AAA domain SecY PF00344.15 AIF84834.1 - 4e-85 285.7 19.6 5e-85 285.4 13.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AIF84834.1 - 5.4e-12 45.0 0.5 5.4e-12 45.0 0.4 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p Ribosomal_L18e PF00828.14 AIF84835.1 - 1.5e-21 77.0 1.0 1.9e-21 76.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L30 PF00327.15 AIF84836.1 - 3.5e-12 45.7 0.0 5.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.15 AIF84837.1 - 6e-19 67.5 0.8 1.1e-18 66.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AIF84837.1 - 2.8e-18 64.9 0.1 4.3e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_L18p PF00861.17 AIF84838.1 - 5.2e-20 71.8 0.4 8.9e-20 71.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 AIF84838.1 - 2e-09 37.8 12.4 2e-09 37.8 8.6 2.1 2 1 0 2 2 2 1 Ribosomal L18 C-terminal region FliD_C PF07195.7 AIF84838.1 - 0.0038 16.5 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus RNase_H2-Ydr279 PF09468.5 AIF84838.1 - 4 6.5 14.5 5.1 6.1 10.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AIRC PF00731.15 AIF84839.1 - 3.2e-22 78.4 9.6 6.2e-22 77.5 6.6 1.5 1 0 0 1 1 1 1 AIR carboxylase CW_binding_2 PF04122.7 AIF84839.1 - 0.026 14.7 3.0 0.035 14.3 0.5 2.3 2 1 0 2 2 2 0 Putative cell wall binding repeat 2 AF0941-like PF14591.1 AIF84839.1 - 0.086 12.8 0.2 0.24 11.4 0.0 1.8 1 1 1 2 2 2 0 AF0941-like Ldh_1_N PF00056.18 AIF84840.1 - 2.3e-36 124.7 0.9 2.3e-36 124.7 0.6 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AIF84840.1 - 7.7e-26 90.8 0.1 1.1e-25 90.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 AIF84840.1 - 0.021 14.1 0.3 0.13 11.5 0.1 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.9 AIF84840.1 - 0.19 11.1 4.4 0.12 11.7 1.0 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Herpes_US9 PF06072.6 AIF84841.1 - 0.041 13.7 0.2 0.072 12.9 0.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4448 PF14610.1 AIF84841.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1254 PF06863.7 AIF84841.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) YcaO PF02624.11 AIF84842.1 - 5.6e-69 233.1 0.0 1.3e-67 228.6 0.0 2.3 2 1 0 2 2 2 1 YcaO-like family TfuA PF07812.7 AIF84843.1 - 4.1e-31 106.8 0.0 5.9e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 TfuA-like protein DUF2164 PF09932.4 AIF84843.1 - 0.024 14.4 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Cob_adeno_trans PF01923.13 AIF84844.1 - 9.1e-56 188.1 0.0 1e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase zf-C2H2 PF00096.21 AIF84846.1 - 3.8e-06 26.9 0.5 4.5e-06 26.6 0.4 1.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF84846.1 - 3.8e-06 26.8 0.3 4.6e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 AIF84846.1 - 3e-05 24.0 0.1 3.6e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 AIF84846.1 - 0.0007 19.6 0.1 0.0007 19.6 0.1 1.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 AIF84846.1 - 0.002 18.2 1.7 0.27 11.6 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-CHCC PF10276.4 AIF84846.1 - 0.0081 15.9 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-finger domain HNH PF01844.18 AIF84846.1 - 0.017 14.9 0.2 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 HNH endonuclease zf-RING_3 PF14369.1 AIF84846.1 - 0.019 14.9 0.2 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 zinc-finger zinc_ribbon_2 PF13240.1 AIF84846.1 - 0.03 13.7 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF2225 PF09986.4 AIF84846.1 - 0.031 13.7 0.0 0.031 13.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 AIF84846.1 - 0.032 14.3 0.1 0.039 14.0 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-ribbon_3 PF13248.1 AIF84846.1 - 0.05 12.8 0.1 0.064 12.4 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Rad50_zn_hook PF04423.9 AIF84846.1 - 0.068 12.6 0.1 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 Rad50 zinc hook motif Cys_rich_CPXG PF14255.1 AIF84846.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG PyrI_C PF02748.10 AIF84846.1 - 0.14 11.5 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HD_3 PF13023.1 AIF84847.1 - 2.4e-35 121.7 0.1 2.9e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 AIF84847.1 - 6.7e-05 22.8 0.6 0.0002 21.3 0.4 1.8 1 1 0 1 1 1 1 HD domain CTI PF06934.6 AIF84847.1 - 0.095 10.9 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Saccharop_dh_N PF04455.7 AIF84849.1 - 6.4e-38 129.0 0.0 1.5e-37 127.8 0.0 1.7 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region Band_7 PF01145.20 AIF84850.1 - 1.3e-32 113.1 7.9 2.3e-32 112.3 5.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 AIF84850.1 - 5.3e-05 22.8 0.5 0.00011 21.7 0.3 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Tyr_Deacylase PF02580.11 AIF84850.1 - 0.0014 18.5 0.1 0.0054 16.7 0.0 2.1 2 0 0 2 2 2 1 D-Tyr-tRNA(Tyr) deacylase DUF3487 PF11990.3 AIF84850.1 - 2.6 7.4 5.1 4.7 6.6 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) SdpI PF13630.1 AIF84850.1 - 5.9 6.6 6.9 10 5.9 4.8 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family SelR PF01641.13 AIF84851.1 - 1.6e-49 166.7 0.3 1.8e-49 166.5 0.2 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 AIF84851.1 - 0.00036 20.4 0.0 0.00065 19.6 0.0 1.4 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 AIF84851.1 - 0.0008 19.1 0.4 0.005 16.6 0.3 2.3 1 1 0 1 1 1 1 Double zinc ribbon GFA PF04828.9 AIF84851.1 - 0.00093 19.0 1.9 0.34 10.8 0.2 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 AIF84851.1 - 0.0036 16.7 0.3 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AIF84851.1 - 0.011 15.0 0.2 4.1 6.7 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding DUF678 PF05077.7 AIF84851.1 - 0.027 14.4 0.1 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-ribbon_3 PF13248.1 AIF84851.1 - 0.033 13.3 3.9 3.5 6.9 0.1 2.7 2 1 0 2 2 2 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.1 AIF84851.1 - 0.038 14.3 0.2 5.4 7.5 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF2296 PF10058.4 AIF84851.1 - 0.04 13.6 0.9 4.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Ribosomal_S27e PF01667.12 AIF84851.1 - 0.05 13.1 0.1 0.95 9.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.5 AIF84851.1 - 0.061 13.2 0.5 7.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-tcix PF14952.1 AIF84851.1 - 0.1 11.9 0.5 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding HECT_2 PF09814.4 AIF84851.1 - 0.14 10.8 0.2 0.4 9.3 0.0 1.7 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF983 PF06170.7 AIF84851.1 - 0.15 12.1 0.3 7.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Lar_restr_allev PF14354.1 AIF84851.1 - 0.17 12.1 4.9 1.7 9.0 0.1 2.4 1 1 0 2 2 2 0 Restriction alleviation protein Lar Endonuclease_7 PF02945.10 AIF84851.1 - 0.28 10.9 1.8 1.9 8.2 1.2 2.2 1 1 0 1 1 1 0 Recombination endonuclease VII zf-HIT PF04438.11 AIF84851.1 - 0.32 10.6 2.4 15 5.3 0.0 2.7 2 1 0 2 2 2 0 HIT zinc finger Zn_ribbon_recom PF13408.1 AIF84851.1 - 0.6 10.4 3.8 8.4 6.7 0.3 2.5 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 AIF84851.1 - 2 8.2 6.3 3.9 7.3 1.2 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain MUG113 PF13455.1 AIF84852.1 - 0.075 13.4 0.3 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 zinc_ribbon_4 PF13717.1 AIF84853.1 - 0.023 14.4 0.2 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF84853.1 - 0.032 13.8 0.2 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain E6 PF00518.12 AIF84853.1 - 0.049 13.9 0.3 0.049 13.9 0.2 1.0 1 0 0 1 1 1 0 Early Protein (E6) RNA_pol_N PF01194.12 AIF84853.1 - 0.083 12.9 0.4 0.086 12.8 0.2 1.3 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit zf-C2HC_2 PF13913.1 AIF84853.1 - 0.3 10.7 2.5 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type YHS PF04945.8 AIF84854.1 - 7.7e-13 48.0 1.9 8e-13 48.0 1.3 1.0 1 0 0 1 1 1 1 YHS domain zinc_ribbon_2 PF13240.1 AIF84854.1 - 0.00097 18.5 2.3 0.013 14.9 1.8 2.1 1 1 1 2 2 2 2 zinc-ribbon domain Arc_trans_TRASH PF08394.5 AIF84854.1 - 0.0011 19.1 2.0 0.0017 18.4 1.4 1.3 1 1 0 1 1 1 1 Archaeal TRASH domain ATPase-cat_bd PF12156.3 AIF84854.1 - 0.0012 19.3 1.6 0.0014 19.1 1.1 1.1 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase zinc_ribbon_4 PF13717.1 AIF84854.1 - 0.0041 16.7 1.5 0.0074 15.9 1.0 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF84854.1 - 0.0041 16.6 1.5 0.0067 15.9 1.0 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-FCS PF06467.9 AIF84854.1 - 0.081 12.5 2.9 0.097 12.3 2.0 1.2 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.1 AIF84854.1 - 0.17 12.2 2.9 0.95 9.9 1.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 AIF84854.1 - 0.17 11.1 2.8 5.9 6.2 1.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AIF84854.1 - 0.23 11.3 2.9 0.16 11.7 1.3 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-Di19 PF05605.7 AIF84854.1 - 0.45 10.6 3.9 0.79 9.8 1.8 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 AIF84854.1 - 4 7.9 8.3 1.3 9.3 4.1 1.6 2 1 0 2 2 1 0 Zinc-finger double domain PadR PF03551.9 AIF84855.1 - 2e-12 46.6 0.0 4.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family TrmB PF01978.14 AIF84855.1 - 0.0035 17.0 0.1 0.04 13.6 0.0 2.6 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 AIF84855.1 - 0.0054 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_IclR PF09339.5 AIF84855.1 - 0.014 14.9 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2067 PF09840.4 AIF84855.1 - 0.039 13.4 0.3 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) DUF4423 PF14394.1 AIF84855.1 - 0.045 13.3 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) DUF1803 PF08820.5 AIF84855.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Zn_clus PF00172.13 AIF84856.1 - 0.018 14.9 1.3 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer4_21 PF14697.1 AIF84856.1 - 0.07 12.9 1.5 0.085 12.7 1.1 1.1 1 0 0 1 1 1 0 4Fe-4S dicluster domain GatB_N PF02934.10 AIF84857.1 - 1.2e-101 339.4 0.0 1.6e-101 338.9 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AIF84857.1 - 8.1e-34 116.4 2.9 1.4e-33 115.6 2.0 1.4 1 0 0 1 1 1 1 GatB domain Amidase PF01425.16 AIF84858.1 - 1.6e-145 485.3 0.2 1.8e-145 485.1 0.1 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.10 AIF84859.1 - 2e-06 27.4 0.1 3.1e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF3375 PF11855.3 AIF84859.1 - 0.055 12.2 0.1 0.071 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) tRNA-synt_2 PF00152.15 AIF84860.1 - 1.2e-85 287.2 0.1 1.6e-85 286.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AIF84860.1 - 9.6e-14 51.0 0.1 1.7e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AIF84860.1 - 0.0016 17.6 0.4 0.0058 15.8 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) DUF937 PF06078.6 AIF84862.1 - 0.021 15.0 5.9 1.3 9.2 0.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) tRNA_SAD PF07973.9 AIF84863.1 - 0.0047 16.7 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AIF84863.1 - 0.0047 16.5 0.7 0.017 14.8 0.5 2.0 1 1 0 1 1 1 1 DHHA1 domain RepA_N PF06970.6 AIF84863.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Cas_Cas1 PF01867.11 AIF84864.1 - 6.4e-14 51.6 0.1 8.2e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 CheR PF01739.13 AIF84864.1 - 0.015 14.6 0.2 0.018 14.2 0.1 1.1 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PD40 PF07676.7 AIF84865.1 - 6.2e-41 137.4 12.7 1.5e-09 37.2 0.1 6.3 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 AIF84865.1 - 1.6e-11 43.3 9.5 0.00014 20.6 1.9 4.2 1 1 3 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.1 AIF84865.1 - 8.7e-06 24.4 1.1 0.043 12.2 0.0 3.3 1 1 1 3 3 3 2 Oligogalacturonate lyase Gmad1 PF10647.4 AIF84865.1 - 0.00011 21.7 0.0 0.61 9.4 0.0 3.5 2 2 2 4 4 4 3 Lipoprotein LpqB beta-propeller domain tRNA_anti-codon PF01336.20 AIF84865.1 - 0.019 14.7 0.8 0.67 9.8 0.0 3.5 4 1 0 4 4 4 0 OB-fold nucleic acid binding domain eIF2A PF08662.6 AIF84865.1 - 0.032 13.9 0.3 3.9 7.1 0.0 2.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4469 PF14734.1 AIF84866.1 - 0.039 13.8 0.0 0.72 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold Abhydrolase_5 PF12695.2 AIF84870.1 - 6.1e-15 55.2 0.0 2.2e-14 53.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AIF84870.1 - 3.7e-12 46.6 0.0 9.7e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIF84870.1 - 6e-11 41.9 0.0 0.00027 20.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 AIF84870.1 - 2.2e-08 33.6 0.0 0.00049 19.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 AIF84870.1 - 4.3e-06 26.5 0.0 0.00074 19.2 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 AIF84870.1 - 3e-05 22.6 0.0 0.0005 18.6 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 AIF84870.1 - 0.00057 19.3 0.0 0.12 11.7 0.0 2.6 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 AIF84870.1 - 0.0036 16.8 0.0 0.0073 15.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold PE-PPE PF08237.6 AIF84870.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.8 AIF84870.1 - 0.04 13.4 0.0 0.088 12.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AIF84870.1 - 0.068 13.0 0.0 0.39 10.5 0.0 2.3 2 1 0 2 2 2 0 Putative lysophospholipase Acyl_transf_2 PF02273.10 AIF84870.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase Pyridox_oxidase PF01243.15 AIF84871.1 - 1.4e-06 28.2 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF84871.1 - 0.00028 20.7 0.0 0.00031 20.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 AIF84873.1 - 1e-27 97.0 0.1 1.6e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIF84873.1 - 5.7e-17 62.2 0.0 7.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF84873.1 - 6.8e-13 48.6 0.1 1.1e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AIF84873.1 - 4.6e-05 22.9 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AIF84873.1 - 0.0024 17.8 1.5 0.051 13.5 1.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding DUF3439 PF11921.3 AIF84873.1 - 1.3 8.7 4.9 4.1 7.1 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) Rieske PF00355.21 AIF84874.1 - 4.5e-08 32.5 0.2 1.2e-07 31.1 0.1 1.7 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain UCR_Fe-S_N PF10399.4 AIF84874.1 - 0.025 13.7 1.0 0.064 12.4 0.7 1.6 1 1 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 AIF84874.1 - 0.036 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence HTH_20 PF12840.2 AIF84875.1 - 9e-08 31.8 0.3 8.7e-07 28.6 0.4 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 AIF84875.1 - 4.1e-06 26.3 1.3 1.3e-05 24.7 0.3 2.1 2 0 0 2 2 2 1 MarR family DUF1724 PF08350.5 AIF84875.1 - 0.0096 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1724) HTH_Crp_2 PF13545.1 AIF84875.1 - 0.014 15.1 0.2 0.079 12.7 0.0 2.2 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_CodY PF08222.6 AIF84875.1 - 0.028 13.7 0.2 8.7 5.7 0.0 3.0 3 0 0 3 3 3 0 CodY helix-turn-helix domain HTH_5 PF01022.15 AIF84875.1 - 0.043 13.4 0.1 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AIF84875.1 - 0.052 12.9 0.1 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 AIF84875.1 - 0.062 12.8 0.1 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.14 AIF84875.1 - 0.082 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AIF84875.1 - 0.1 12.2 0.3 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 HTH domain MarR PF01047.17 AIF84875.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 MarR family MazG-like PF12643.2 AIF84875.1 - 0.15 12.0 0.2 0.53 10.2 0.0 2.0 3 0 0 3 3 3 0 MazG-like family CarboxypepD_reg PF13620.1 AIF84876.1 - 3e-10 40.0 0.1 7.2e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 AIF84876.1 - 0.079 13.0 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) 7TM-7TMR_HD PF07698.6 AIF84877.1 - 0.07 12.5 5.1 0.1 12.0 3.3 1.4 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF1632 PF07857.7 AIF84877.1 - 1.7 7.8 5.8 0.15 11.2 0.7 1.6 2 0 0 2 2 2 0 CEO family (DUF1632) DUF202 PF02656.10 AIF84877.1 - 2.5 8.3 8.6 1e+02 3.2 6.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF308 PF03729.8 AIF84877.1 - 9 6.3 18.0 0.24 11.4 3.7 2.6 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) DUF1297 PF06973.7 AIF84878.1 - 4e-73 244.7 0.0 5.2e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 AIF84878.1 - 8.3e-46 154.7 0.0 1.2e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_4 PF13535.1 AIF84878.1 - 0.00079 19.1 0.0 0.014 15.1 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AIF84878.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ehbp PF10622.4 AIF84878.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) V-set PF07686.12 AIF84879.1 - 0.027 14.3 0.0 0.078 12.8 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain HTH_5 PF01022.15 AIF84883.1 - 1e-13 50.7 0.1 1e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AIF84883.1 - 1.5e-10 40.2 0.0 5.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AIF84883.1 - 3.2e-09 36.3 0.3 5.4e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 MarR family HTH_20 PF12840.2 AIF84883.1 - 7.6e-09 35.2 0.1 0.0005 19.8 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_34 PF13601.1 AIF84883.1 - 3.6e-06 26.9 0.0 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR PF01047.17 AIF84883.1 - 1.6e-05 24.5 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 2 MarR family TrmB PF01978.14 AIF84883.1 - 8.5e-05 22.1 0.1 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 AIF84883.1 - 9e-05 21.9 0.0 0.00028 20.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain LexA_DNA_bind PF01726.11 AIF84883.1 - 0.0001 21.8 0.3 0.2 11.2 0.0 2.8 2 2 0 2 2 2 2 LexA DNA binding domain HTH_Crp_2 PF13545.1 AIF84883.1 - 0.0004 20.1 0.2 0.042 13.6 0.0 2.9 2 2 0 2 2 2 1 Crp-like helix-turn-helix domain Rrf2 PF02082.15 AIF84883.1 - 0.0005 20.1 0.1 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator Sulfolobus_pRN PF05584.6 AIF84883.1 - 0.0011 18.8 0.1 0.023 14.6 0.0 2.4 2 1 0 2 2 2 1 Sulfolobus plasmid regulatory protein HTH_IclR PF09339.5 AIF84883.1 - 0.0012 18.3 0.1 0.023 14.2 0.0 2.3 2 1 0 2 2 2 1 IclR helix-turn-helix domain DUF2513 PF10711.4 AIF84883.1 - 0.0068 16.4 0.0 1.7 8.7 0.0 2.6 2 1 0 2 2 2 1 Hypothetical protein (DUF2513) Penicillinase_R PF03965.11 AIF84883.1 - 0.013 15.5 0.1 0.06 13.4 0.0 2.1 2 1 0 2 2 2 0 Penicillinase repressor HTH_40 PF14493.1 AIF84883.1 - 0.044 14.0 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.7 AIF84883.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_36 PF13730.1 AIF84883.1 - 0.097 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2177 PF09945.4 AIF84884.1 - 0.12 12.4 3.4 0.19 11.7 2.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) Arteri_Gl PF00951.13 AIF84884.1 - 1.2 8.7 6.7 1.4 8.4 4.2 1.4 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein CopD PF05425.8 AIF84885.1 - 2e-17 63.3 8.7 2e-17 63.3 6.0 4.1 5 1 0 5 5 5 1 Copper resistance protein D CopC PF04234.7 AIF84885.1 - 2.7e-13 50.3 0.0 6.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 CopC domain UPF0093 PF03653.8 AIF84885.1 - 0.061 13.2 1.0 0.16 11.9 0.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) DUF3529 PF12046.3 AIF84885.1 - 0.17 10.8 3.2 0.24 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) CopC PF04234.7 AIF84887.1 - 8.4e-19 67.9 0.0 2.3e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 CopC domain SGL PF08450.7 AIF84887.1 - 3.8e-15 55.9 0.2 3.4e-05 23.3 0.0 3.8 2 2 1 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region CopD PF05425.8 AIF84887.1 - 1.7e-10 41.0 6.2 1.7e-10 41.0 4.3 3.4 2 1 1 3 3 3 1 Copper resistance protein D Reg_prop PF07494.6 AIF84887.1 - 1.7e-06 27.3 9.4 6 7.2 0.0 7.3 8 0 0 8 8 8 2 Two component regulator propeller DUF4149 PF13664.1 AIF84887.1 - 1.5e-05 24.9 5.1 1.5e-05 24.9 3.5 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) YtkA PF13115.1 AIF84887.1 - 0.00082 19.6 0.1 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 YtkA-like NHL PF01436.16 AIF84887.1 - 0.06 13.3 1.1 35 4.6 0.0 4.2 4 0 0 4 4 4 0 NHL repeat YtkA PF13115.1 AIF84888.1 - 0.0011 19.3 0.2 0.0024 18.2 0.1 1.7 1 1 0 1 1 1 1 YtkA-like phage_tail_N PF08400.5 AIF84888.1 - 0.0091 15.6 1.6 0.021 14.5 1.1 1.7 1 1 0 1 1 1 1 Prophage tail fibre N-terminal ApoO PF09769.4 AIF84888.1 - 0.11 12.2 0.5 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Apolipoprotein O DUF1628 PF07790.6 AIF84888.1 - 0.62 10.8 3.6 2.8 8.7 0.1 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1628) Filamin PF00630.14 AIF84889.1 - 0.0095 16.4 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat PPC PF04151.10 AIF84889.1 - 0.026 15.5 0.0 0.045 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Copper-bind PF00127.15 AIF84891.1 - 1e-08 35.2 1.7 2.1e-06 27.8 0.0 2.5 2 1 1 3 3 3 3 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF84891.1 - 1.5e-06 28.0 0.9 0.0011 18.8 0.0 2.7 2 2 0 2 2 2 2 Cupredoxin-like domain DUF796 PF05638.7 AIF84891.1 - 0.048 13.6 1.0 0.076 13.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF796) Peripla_BP_2 PF01497.13 AIF84892.1 - 3e-40 137.8 0.0 3.6e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Ribosomal_S10 PF00338.17 AIF84893.1 - 2.3e-26 91.4 0.0 2.6e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GTP_EFTU PF00009.22 AIF84894.1 - 2.7e-50 170.4 0.0 5.8e-50 169.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AIF84894.1 - 4.9e-30 103.6 0.1 1.5e-29 102.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AIF84894.1 - 9e-17 60.9 1.9 9e-17 60.9 1.3 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AIF84894.1 - 1.8e-06 27.5 1.5 3.9e-06 26.3 1.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AIF84894.1 - 0.00023 21.0 0.0 0.00058 19.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AIF84894.1 - 0.0021 18.5 0.1 0.012 16.0 0.1 2.2 1 1 0 1 1 1 1 Miro-like protein YajC PF02699.10 AIF84894.1 - 0.053 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2228 PF10228.4 AIF84894.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) NTPase_1 PF03266.10 AIF84894.1 - 0.089 12.4 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 NTPase Gtr1_RagA PF04670.7 AIF84894.1 - 0.18 10.8 0.0 0.74 8.9 0.0 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FBPase_3 PF01950.11 AIF84895.1 - 4.6e-151 502.9 0.0 5.2e-151 502.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase YopR_core PF09025.5 AIF84895.1 - 0.16 11.9 0.0 17 5.3 0.0 2.3 1 1 1 2 2 2 0 YopR Core TIM PF00121.13 AIF84896.1 - 1.1e-24 86.8 0.5 3.3e-22 78.7 0.3 2.0 1 1 0 1 1 1 1 Triosephosphate isomerase ThiG PF05690.9 AIF84896.1 - 2.3e-05 23.5 1.0 3.2e-05 23.1 0.2 1.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 AIF84896.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.13 AIF84896.1 - 0.0065 15.3 0.3 0.0065 15.3 0.2 1.7 2 1 1 3 3 3 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 AIF84896.1 - 0.046 12.9 0.3 0.093 11.9 0.1 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 AIF84896.1 - 0.067 12.3 0.7 0.95 8.5 0.1 2.0 2 0 0 2 2 2 0 Nitronate monooxygenase Methyltransf_31 PF13847.1 AIF84897.1 - 2.7e-18 65.9 0.1 6.8e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84897.1 - 4.5e-17 62.6 0.4 1.7e-16 60.7 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF84897.1 - 5.1e-14 52.5 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84897.1 - 4.8e-12 46.2 0.3 2e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84897.1 - 2.1e-11 43.7 0.2 5.3e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84897.1 - 7.2e-09 35.9 1.1 9e-09 35.6 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 AIF84897.1 - 2.7e-08 33.3 0.2 7.9e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AIF84897.1 - 5.5e-08 32.8 0.3 4.7e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 AIF84897.1 - 4.7e-07 29.5 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.12 AIF84897.1 - 6.6e-06 25.3 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 AIF84897.1 - 7.2e-06 26.7 0.1 2.3e-05 25.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF84897.1 - 2.5e-05 23.5 0.0 3.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 AIF84897.1 - 6.9e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 AIF84897.1 - 0.00012 21.3 0.2 0.0028 16.8 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase PrmA PF06325.8 AIF84897.1 - 0.00027 20.1 0.5 0.0013 17.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 AIF84897.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.9 AIF84897.1 - 0.0042 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.5 AIF84897.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.12 AIF84897.1 - 0.031 13.3 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase FmrO PF07091.6 AIF84897.1 - 0.046 12.6 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 AIF84897.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0126 PF03458.8 AIF84898.1 - 1.6e-44 149.4 29.2 1.4e-24 85.4 5.4 2.5 2 1 1 3 3 3 2 UPF0126 domain PRA1 PF03208.14 AIF84898.1 - 1.8 7.9 10.0 12 5.2 7.0 2.2 1 1 0 1 1 1 0 PRA1 family protein PEP-utilizers_C PF02896.13 AIF84899.1 - 2.1e-90 302.5 3.0 3e-90 302.0 2.1 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 AIF84899.1 - 8.2e-64 215.7 0.0 2.6e-63 214.0 0.0 1.8 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 AIF84899.1 - 6.5e-24 83.3 0.4 2.1e-23 81.6 0.3 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.9 AIF84899.1 - 0.0067 15.3 0.1 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.11 AIF84900.1 - 8e-42 143.2 52.8 1.4e-40 139.1 35.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AIF84900.1 - 1.4e-08 33.8 13.9 1.4e-08 33.8 9.7 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AIF84900.1 - 4.6e-05 21.9 9.9 4.6e-05 21.9 6.8 4.1 1 1 2 3 3 3 1 MFS/sugar transport protein Methyltransf_11 PF08241.7 AIF84901.1 - 1.5e-22 79.8 0.0 2.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84901.1 - 1.4e-21 76.6 0.0 2.8e-21 75.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84901.1 - 4.4e-21 75.2 0.0 6.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF84901.1 - 3.2e-15 55.8 0.0 1.9e-14 53.3 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 AIF84901.1 - 3.5e-15 56.2 0.0 7.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84901.1 - 5.5e-14 52.6 0.0 1.7e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84901.1 - 2e-12 47.4 0.0 4.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF84901.1 - 2.2e-10 40.5 0.0 4.3e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF84901.1 - 4.7e-10 39.0 0.0 7.5e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 AIF84901.1 - 5.1e-08 32.7 0.0 8.5e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 AIF84901.1 - 3.1e-07 29.8 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase NodS PF05401.6 AIF84901.1 - 3.4e-06 26.5 0.0 5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 AIF84901.1 - 3.7e-06 26.6 0.0 6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 AIF84901.1 - 1.1e-05 24.6 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 AIF84901.1 - 5.7e-05 22.1 0.0 8.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.7 AIF84901.1 - 6.3e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.5 AIF84901.1 - 0.00043 19.8 0.0 0.00079 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 AIF84901.1 - 0.00099 18.3 0.0 0.0043 16.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 AIF84901.1 - 0.0049 16.5 0.0 0.01 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIF84901.1 - 0.0063 15.6 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 AIF84901.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 AIF84901.1 - 0.027 13.6 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.11 AIF84901.1 - 0.056 12.2 0.0 0.59 8.9 0.0 2.1 1 1 0 1 1 1 0 mRNA capping enzyme GCM PF03615.10 AIF84901.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 GCM motif protein MethyltransfD12 PF02086.10 AIF84901.1 - 0.1 12.0 0.7 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DNA_RNApol_7kD PF03604.8 AIF84902.1 - 3.7e-06 26.2 2.4 6.2e-06 25.5 1.7 1.4 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.1 AIF84902.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glycos_transf_1 PF00534.15 AIF84902.1 - 0.092 12.1 0.1 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-CSL PF05207.8 AIF84902.1 - 0.1 12.1 3.3 0.25 10.8 1.8 1.8 1 1 1 2 2 2 0 CSL zinc finger zf-C2H2 PF00096.21 AIF84903.1 - 2e-08 34.0 6.1 0.00036 20.6 0.9 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF84903.1 - 3.2e-08 33.3 2.2 0.0012 18.9 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIF84903.1 - 0.00024 20.8 8.1 0.00068 19.4 1.3 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 AIF84903.1 - 0.0004 20.2 5.2 0.15 12.0 0.2 2.3 2 0 0 2 2 2 2 Zinc ribbon domain GATA PF00320.22 AIF84903.1 - 0.0029 16.9 0.5 0.77 9.1 0.1 2.2 2 0 0 2 2 2 1 GATA zinc finger SAE2 PF08573.5 AIF84903.1 - 0.0031 18.1 6.7 0.34 11.6 0.9 2.0 1 1 1 2 2 2 2 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-C2H2_jaz PF12171.3 AIF84903.1 - 0.0034 17.4 5.3 1 9.5 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF1610 PF07754.6 AIF84903.1 - 0.0036 17.3 2.1 0.81 9.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.1 AIF84903.1 - 0.0038 17.4 12.2 0.12 12.6 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger double domain PhnA_Zn_Ribbon PF08274.7 AIF84903.1 - 0.013 15.2 0.5 0.057 13.2 0.3 1.8 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-ISL3 PF14690.1 AIF84903.1 - 0.013 15.4 2.3 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.1 AIF84903.1 - 0.028 13.8 4.2 0.087 12.3 2.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 AIF84903.1 - 0.031 14.3 9.6 0.81 9.8 1.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ogr_Delta PF04606.7 AIF84903.1 - 0.031 13.9 0.5 0.044 13.4 0.3 1.2 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger FYVE PF01363.16 AIF84903.1 - 0.035 13.9 5.7 0.14 12.0 3.6 1.9 1 1 1 2 2 2 0 FYVE zinc finger zf-DBF PF07535.7 AIF84903.1 - 0.038 13.6 6.6 0.61 9.8 1.6 2.4 1 1 1 2 2 2 0 DBF zinc finger zf-Di19 PF05605.7 AIF84903.1 - 0.045 13.8 2.6 0.063 13.4 1.8 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 AIF84903.1 - 0.047 13.3 5.7 0.049 13.3 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.2 AIF84903.1 - 0.057 13.2 3.2 0.095 12.5 2.2 1.4 1 1 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.8 AIF84903.1 - 0.065 10.8 1.0 0.073 10.7 0.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 XPA_N PF01286.13 AIF84903.1 - 0.073 12.7 5.6 0.34 10.6 0.5 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-HIT PF04438.11 AIF84903.1 - 0.082 12.5 1.2 4.5 6.9 0.1 2.2 2 0 0 2 2 2 0 HIT zinc finger Terminase_GpA PF05876.7 AIF84903.1 - 0.089 11.1 2.7 0.09 11.1 1.9 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 AIF84903.1 - 0.14 11.4 1.9 1.1 8.6 1.3 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding Prok-RING_1 PF14446.1 AIF84903.1 - 0.14 11.8 5.1 1.2 8.9 0.5 2.2 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 HNH PF01844.18 AIF84903.1 - 0.18 11.7 2.9 5.2 7.0 0.3 2.2 2 0 0 2 2 2 0 HNH endonuclease OrfB_Zn_ribbon PF07282.6 AIF84903.1 - 0.19 11.4 4.5 0.43 10.2 3.1 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 AIF84903.1 - 0.19 12.0 2.1 0.41 10.9 1.4 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_5 PF13719.1 AIF84903.1 - 0.2 11.2 2.6 1.9 8.1 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.9 AIF84903.1 - 0.25 11.0 1.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.2 AIF84903.1 - 0.29 10.9 3.9 0.65 9.8 2.7 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain CpXC PF14353.1 AIF84903.1 - 0.36 10.8 5.0 3.3 7.6 3.4 2.1 1 1 0 1 1 1 0 CpXC protein NADH_4Fe-4S PF10589.4 AIF84903.1 - 0.39 9.8 4.1 0.44 9.7 0.0 2.4 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region zinc_ribbon_4 PF13717.1 AIF84903.1 - 0.47 10.1 3.6 2.7 7.7 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.1 AIF84903.1 - 0.48 10.3 8.5 2.4 8.1 1.8 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc-ribbons_6 PF07191.7 AIF84903.1 - 0.55 10.0 4.7 3 7.7 0.3 2.1 1 1 1 2 2 2 0 zinc-ribbons DUF629 PF04780.7 AIF84903.1 - 0.72 8.2 6.6 0.46 8.9 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) C1_4 PF07975.7 AIF84903.1 - 0.95 9.5 5.8 3.3 7.7 3.9 1.9 1 1 1 2 2 2 0 TFIIH C1-like domain FYDLN_acid PF09538.5 AIF84903.1 - 1 9.9 3.9 17 6.0 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) A2L_zn_ribbon PF08792.5 AIF84903.1 - 1.5 8.3 4.6 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-IS66 PF13005.2 AIF84903.1 - 1.7 8.6 5.8 2.2 8.3 1.5 2.1 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF1936 PF09151.5 AIF84903.1 - 2.9 7.4 5.9 5.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) TFIIS_C PF01096.13 AIF84903.1 - 2.9 7.5 8.5 2.5 7.7 0.6 2.5 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Cas_CXXC_CXXC PF09706.5 AIF84903.1 - 4 7.6 7.0 13 6.0 0.5 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF4428 PF14471.1 AIF84904.1 - 0.0022 17.7 15.1 0.084 12.6 0.7 4.1 3 3 0 3 3 3 2 Domain of unknown function (DUF4428) Cytochrom_c3_2 PF14537.1 AIF84904.1 - 0.007 16.6 11.1 0.0091 16.3 6.0 2.2 2 1 0 2 2 2 1 Cytochrome c3 zf-C4pol PF14260.1 AIF84904.1 - 0.015 15.2 10.3 0.29 11.1 0.6 3.2 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Cytochrome_C7 PF14522.1 AIF84904.1 - 0.03 13.9 15.7 0.7 9.5 6.4 3.0 1 1 1 2 2 2 0 Cytochrome c7 C1_1 PF00130.17 AIF84904.1 - 0.044 13.5 14.9 2.4 7.9 0.2 3.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1451 PF07295.6 AIF84904.1 - 0.048 13.4 1.2 0.048 13.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DZR PF12773.2 AIF84904.1 - 0.053 13.3 18.2 2e+03 -1.4 12.6 3.5 1 1 0 1 1 1 0 Double zinc ribbon ZZ PF00569.12 AIF84904.1 - 0.061 12.8 0.1 0.061 12.8 0.1 3.8 5 1 0 5 5 5 0 Zinc finger, ZZ type FYVE PF01363.16 AIF84904.1 - 0.079 12.8 16.0 3.2e+02 1.2 11.1 3.2 1 1 0 1 1 1 0 FYVE zinc finger zf-NADH-PPase PF09297.6 AIF84904.1 - 0.09 12.3 0.3 0.09 12.3 0.2 4.0 6 0 0 6 6 4 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_S14 PF00253.16 AIF84904.1 - 0.091 12.1 4.0 0.3 10.4 0.8 2.9 2 1 0 2 2 2 0 Ribosomal protein S14p/S29e Zn_ribbon_recom PF13408.1 AIF84904.1 - 0.13 12.5 12.1 0.29 11.4 1.6 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain LIM PF00412.17 AIF84904.1 - 0.14 12.2 13.1 1.5 8.9 0.0 3.5 3 2 0 3 3 3 0 LIM domain Multi-haem_cyto PF13447.1 AIF84904.1 - 0.4 9.7 11.5 0.62 9.0 8.0 1.4 1 1 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH Vps39_2 PF10367.4 AIF84904.1 - 0.45 10.7 7.5 0.055 13.6 1.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-ribbon_3 PF13248.1 AIF84904.1 - 0.58 9.4 0.1 0.58 9.4 0.1 2.9 4 0 0 4 4 3 0 zinc-ribbon domain zf-CHY PF05495.7 AIF84904.1 - 0.66 10.1 18.6 2.3 8.4 2.3 3.0 1 1 2 3 3 3 0 CHY zinc finger zinc_ribbon_2 PF13240.1 AIF84904.1 - 0.7 9.4 0.1 0.7 9.4 0.1 3.8 4 1 0 4 4 3 0 zinc-ribbon domain DUF983 PF06170.7 AIF84904.1 - 1.6 8.8 5.4 7.1 6.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Cytochrome_C554 PF13435.1 AIF84904.1 - 1.7 8.7 12.4 1.5 8.8 6.8 2.1 1 1 1 2 2 2 0 Cytochrome c554 and c-prime HypA PF01155.14 AIF84904.1 - 2.7 7.7 13.4 0.073 12.7 1.7 2.7 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-UDP PF14569.1 AIF84904.1 - 4.3 7.1 7.1 8.5 6.2 1.2 2.9 2 1 1 3 3 3 0 Zinc-binding RING-finger Nudix_N_2 PF14803.1 AIF84904.1 - 8.9 6.0 14.3 3.8 7.2 0.2 3.9 4 1 0 4 4 4 0 Nudix N-terminal P-II PF00543.17 AIF84905.1 - 5.7e-17 62.0 0.4 6.6e-17 61.8 0.2 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II RHH_1 PF01402.16 AIF84906.1 - 0.0014 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF1449 PF07290.6 AIF84907.1 - 0.056 12.7 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF1326 PF07040.6 AIF84908.1 - 2.3e-44 151.3 0.0 2.6e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1326) P-II PF00543.17 AIF84909.1 - 9.3e-19 67.7 0.1 1.1e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Fil_haemagg PF05594.9 AIF84910.1 - 0.038 14.3 23.7 3.5 8.0 11.8 3.1 1 1 1 2 2 2 0 Haemagluttinin repeat adh_short_C2 PF13561.1 AIF84911.1 - 4.1e-35 121.6 0.2 4.8e-35 121.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AIF84911.1 - 2.2e-32 112.2 0.4 2.8e-32 111.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AIF84911.1 - 9.7e-11 41.6 0.2 1.4e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AIF84911.1 - 1.6e-08 34.7 0.3 2.6e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AIF84911.1 - 1.9e-08 34.0 0.3 9e-08 31.8 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 AIF84911.1 - 2.5e-06 27.6 0.7 5.4e-06 26.5 0.2 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AIF84911.1 - 7.1e-06 25.2 0.4 1e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 AIF84911.1 - 2.5e-05 23.3 0.7 3.5e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AIF84911.1 - 9.7e-05 21.2 0.1 0.00013 20.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 AIF84911.1 - 0.00015 22.0 1.6 0.0003 21.1 1.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 AIF84911.1 - 0.00024 20.0 0.2 0.0004 19.3 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.13 AIF84911.1 - 0.00058 19.8 0.6 0.001 19.0 0.4 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 AIF84911.1 - 0.00074 19.2 1.1 0.0011 18.6 0.8 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 AIF84911.1 - 0.0017 17.6 1.2 0.0086 15.3 0.5 2.0 2 0 0 2 2 2 1 NmrA-like family ApbA PF02558.11 AIF84911.1 - 0.0047 16.3 0.1 0.0074 15.7 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF3842 PF12953.2 AIF84911.1 - 0.0076 16.4 3.0 0.027 14.6 0.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3842) CoA_binding_2 PF13380.1 AIF84911.1 - 0.013 15.6 0.1 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain RmlD_sub_bind PF04321.12 AIF84911.1 - 0.013 14.4 0.3 0.055 12.3 0.1 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 AIF84911.1 - 0.028 14.2 0.1 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AIF84911.1 - 0.052 12.6 0.2 0.086 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 AIF84911.1 - 0.072 13.4 0.3 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DHHA1 PF02272.14 AIF84912.1 - 8.4e-05 22.1 0.1 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.15 AIF84912.1 - 0.00028 20.5 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 DHH family HAD_2 PF13419.1 AIF84913.1 - 3.2e-23 82.8 0.0 4.1e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIF84913.1 - 9.7e-09 35.9 1.0 4.5e-08 33.7 0.7 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AIF84913.1 - 9e-06 25.3 0.0 2.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 AIF84913.1 - 5.6e-05 23.3 0.0 6.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 AIF84913.1 - 0.0035 16.8 0.1 0.0064 16.0 0.1 1.5 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_6 PF13344.1 AIF84913.1 - 0.09 12.6 0.2 2.2 8.2 0.1 2.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NIF PF03031.13 AIF84913.1 - 0.095 12.3 0.0 1.9 8.1 0.0 2.1 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase tRNA-synt_1f PF01921.13 AIF84916.1 - 9.1e-106 353.5 0.0 1.2e-105 353.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.6 AIF84916.1 - 0.044 12.4 0.5 0.38 9.3 0.0 2.5 2 1 1 3 3 3 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AIF84916.1 - 0.079 10.9 0.0 0.12 10.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Radical_SAM PF04055.16 AIF84917.1 - 5.7e-22 78.6 0.0 2.5e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AIF84917.1 - 3.1e-10 39.9 0.3 9.7e-10 38.3 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AIF84917.1 - 0.11 12.6 0.1 0.38 10.8 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AIRS_C PF02769.17 AIF84918.1 - 1e-19 71.0 0.1 2e-19 70.0 0.0 1.5 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AIF84918.1 - 2.2e-17 63.0 0.3 4.9e-17 61.9 0.2 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF190 PF02641.10 AIF84919.1 - 2.5e-19 68.9 0.1 2.9e-19 68.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 DUF3240 PF11582.3 AIF84919.1 - 0.043 13.7 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) UreD PF01774.12 AIF84922.1 - 2.6e-47 161.0 0.0 3.1e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein cobW PF02492.14 AIF84923.1 - 2.2e-34 118.4 0.0 2.5e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AIF84923.1 - 9.7e-09 34.3 1.2 2.2e-08 33.2 0.8 1.5 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 AIF84923.1 - 5.9e-07 29.2 0.1 1.8e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 AIF84923.1 - 0.0043 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 NTPase GTP_EFTU PF00009.22 AIF84923.1 - 0.013 14.9 0.0 6.9 6.0 0.0 2.8 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.16 AIF84923.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 AIF84923.1 - 0.044 14.0 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 AIF84923.1 - 0.06 13.1 0.5 0.36 10.6 0.2 2.2 2 1 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 AIF84923.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain LpxK PF02606.9 AIF84923.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_10 PF12846.2 AIF84923.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain UreF PF01730.11 AIF84924.1 - 5.5e-27 94.6 0.0 7.1e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 UreF UreE_N PF02814.10 AIF84925.1 - 1.2e-10 40.7 0.1 2.3e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain UreE_C PF05194.7 AIF84925.1 - 1.2e-07 31.7 0.3 1.9e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain DNA_ligase_OB PF03120.11 AIF84925.1 - 0.069 12.8 0.3 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Cpn60_TCP1 PF00118.19 AIF84927.1 - 2.6e-106 356.1 6.7 3.3e-106 355.8 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Amidohydro_1 PF01979.15 AIF84928.1 - 2e-53 182.1 5.2 2.6e-53 181.8 3.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 AIF84928.1 - 1.3e-49 167.3 2.0 3.5e-49 165.9 1.4 1.8 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.6 AIF84928.1 - 4.6e-06 26.1 1.7 4.6e-06 26.1 1.2 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 AIF84928.1 - 0.015 15.1 1.0 0.015 15.1 0.7 2.5 3 0 0 3 3 3 0 Amidohydrolase Urease_beta PF00699.15 AIF84929.1 - 1.8e-41 140.0 0.0 2.4e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Urease beta subunit DUF4232 PF14016.1 AIF84929.1 - 0.092 12.3 0.1 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) Urease_gamma PF00547.13 AIF84930.1 - 3.9e-44 148.6 0.1 4.3e-44 148.5 0.1 1.0 1 0 0 1 1 1 1 Urease, gamma subunit UT PF03253.9 AIF84932.1 - 4.2e-50 170.3 31.9 6.9e-22 77.7 6.1 3.1 2 1 1 3 3 3 3 Urea transporter SSF PF00474.12 AIF84933.1 - 9.5e-25 87.0 38.2 9.5e-25 87.0 26.5 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family Usp PF00582.21 AIF84933.1 - 8.5e-23 81.1 0.0 1.7e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Universal stress protein family HTH_24 PF13412.1 AIF84934.1 - 0.0043 16.3 0.9 1.4 8.3 0.1 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding ParBc PF02195.13 AIF84935.1 - 2.4e-19 69.2 0.8 3.4e-18 65.5 0.0 2.4 2 1 0 2 2 2 1 ParB-like nuclease domain KorB PF08535.5 AIF84935.1 - 1.3e-08 34.8 0.2 2.9e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 KorB domain HTH_5 PF01022.15 AIF84935.1 - 0.025 14.2 1.1 0.15 11.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family GIDA PF01134.17 AIF84935.1 - 0.04 12.7 0.3 0.14 11.0 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF745 PF05335.8 AIF84935.1 - 0.11 11.9 3.3 0.18 11.3 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF2572 PF10833.3 AIF84935.1 - 1 8.7 5.6 0.3 10.4 1.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2572) DUF1395 PF07160.7 AIF84936.1 - 0.053 13.0 0.1 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Usp PF00582.21 AIF84937.1 - 3.7e-35 121.1 0.2 4.5e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family Pterin_bind PF00809.17 AIF84937.1 - 0.02 14.2 0.4 4.2 6.6 0.0 2.1 1 1 1 2 2 2 0 Pterin binding enzyme ETF_QO PF05187.8 AIF84941.1 - 0.038 14.0 0.9 0.11 12.5 0.1 1.9 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase SSF PF00474.12 AIF84942.1 - 9.6e-30 103.5 28.3 9.6e-30 103.5 19.6 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family ParBc PF02195.13 AIF84944.1 - 3.3e-11 43.1 0.0 8e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain KorB PF08535.5 AIF84944.1 - 6.1e-06 26.3 0.3 9e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 KorB domain HTH_23 PF13384.1 AIF84944.1 - 0.0047 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.8 AIF84944.1 - 0.013 14.8 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.15 AIF84944.1 - 0.026 14.4 0.1 1 9.3 0.0 2.6 2 1 0 2 2 2 0 Transposase RHH_1 PF01402.16 AIF84944.1 - 0.033 14.0 0.0 2 8.4 0.0 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HTH_28 PF13518.1 AIF84944.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 AIF84944.1 - 0.093 12.3 0.2 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain Arginase PF00491.16 AIF84945.1 - 2.3e-76 256.7 0.0 2.6e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family Urease_gamma PF00547.13 AIF84946.1 - 9.3e-14 51.2 0.1 1.2e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 Urease, gamma subunit NicO PF03824.11 AIF84947.1 - 1.5e-20 73.7 21.0 3.1e-20 72.6 14.6 1.4 1 1 0 1 1 1 1 High-affinity nickel-transport protein Peptidase_S28 PF05577.7 AIF84947.1 - 0.14 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 NikR_C PF08753.6 AIF84948.1 - 3.2e-23 81.4 3.7 5.5e-23 80.6 2.5 1.4 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.16 AIF84948.1 - 0.043 13.7 0.6 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Cpn60_TCP1 PF00118.19 AIF84949.1 - 4.2e-137 457.7 5.1 4.8e-137 457.5 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3235 PF11574.3 AIF84949.1 - 0.04 14.1 0.4 5.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Glyco_tran_28_C PF04101.11 AIF84949.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Urease_gamma PF00547.13 AIF84950.1 - 6e-46 154.5 0.0 6.6e-46 154.3 0.0 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 AIF84951.1 - 6.1e-41 138.3 0.0 7.1e-41 138.0 0.0 1.1 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_1 PF01979.15 AIF84952.1 - 1.5e-64 218.7 4.2 1.9e-64 218.4 2.9 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 AIF84952.1 - 1.7e-39 134.6 3.5 3.4e-39 133.7 2.4 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_5 PF13594.1 AIF84952.1 - 1.1e-07 31.5 4.0 1.1e-07 31.5 2.8 3.2 4 0 0 4 4 4 1 Amidohydrolase Amidohydro_3 PF07969.6 AIF84952.1 - 0.00018 20.8 5.1 0.0064 15.7 1.0 2.9 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 AIF84952.1 - 0.00024 21.2 0.9 0.38 10.7 0.6 2.4 2 0 0 2 2 2 2 Amidohydrolase Dioxygenase_C PF00775.16 AIF84954.1 - 5.5e-14 51.8 0.0 9.7e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Citrate_synt PF00285.16 AIF84955.1 - 3.3e-131 437.2 0.0 3.7e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Bac_luciferase PF00296.15 AIF84957.1 - 2.2e-62 210.9 0.0 2.7e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Lactamase_B_2 PF12706.2 AIF84958.1 - 1.7e-07 31.0 0.3 2.8e-05 23.7 0.3 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AIF84958.1 - 0.00028 20.6 0.0 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AIF84958.1 - 0.027 14.2 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase DRMBL PF07522.9 AIF84958.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase LytR_C PF13399.1 AIF84958.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Lactamase_B PF00753.22 AIF84958.1 - 0.21 11.2 1.8 0.9 9.1 0.4 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Formyl_trans_N PF00551.14 AIF84959.1 - 1.1e-47 161.8 0.0 1.3e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase MFS_1 PF07690.11 AIF84960.1 - 5.2e-35 120.8 48.8 2.7e-24 85.5 9.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 AIF84960.1 - 6.3e-05 22.5 12.9 0.00038 19.9 2.7 2.4 2 0 0 2 2 2 2 Ion channel regulatory protein UNC-93 DUF1228 PF06779.9 AIF84960.1 - 0.0055 16.7 2.3 0.0055 16.7 1.6 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) MFS_3 PF05977.8 AIF84960.1 - 0.012 13.7 22.5 0.017 13.2 15.6 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector ApoO PF09769.4 AIF84960.1 - 0.42 10.3 1.9 0.85 9.3 1.3 1.4 1 0 0 1 1 1 0 Apolipoprotein O Ubie_methyltran PF01209.13 AIF84961.1 - 2e-21 76.2 0.0 2.2e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AIF84961.1 - 3.3e-16 59.5 0.0 5.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84961.1 - 8.5e-12 45.6 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84961.1 - 7.5e-11 42.0 0.0 9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84961.1 - 3.6e-10 39.6 0.0 5.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84961.1 - 1.4e-09 38.2 0.0 2.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84961.1 - 3e-08 33.9 0.0 5.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF84961.1 - 3.8e-05 23.6 0.1 7.7e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF84961.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 AIF84961.1 - 0.0031 17.1 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Eno-Rase_NADH_b PF12242.3 AIF84961.1 - 0.0086 15.8 0.0 0.022 14.5 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DEAD PF00270.24 AIF84962.1 - 1.4e-32 112.5 0.0 2.9e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 AIF84962.1 - 1.6e-12 47.8 0.2 1e-11 45.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 AIF84962.1 - 1e-10 41.3 0.0 5.4e-08 32.5 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 AIF84962.1 - 0.012 15.4 0.0 0.055 13.3 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit zinc_ribbon_5 PF13719.1 AIF84962.1 - 0.024 14.2 1.0 0.024 14.2 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SNF2_N PF00176.18 AIF84962.1 - 0.039 12.7 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain zinc_ribbon_4 PF13717.1 AIF84962.1 - 0.52 10.0 8.9 0.038 13.6 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Topoisom_I_N PF02919.10 AIF84963.1 - 1.8e-63 213.7 1.0 1.8e-63 213.7 0.7 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AIF84963.1 - 1.6e-55 187.7 4.5 2.9e-55 186.9 3.1 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 AIF84963.1 - 1.7e-22 78.8 2.6 3.6e-22 77.7 0.7 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain SAG PF04092.8 AIF84963.1 - 0.29 11.5 2.0 0.74 10.2 1.4 1.7 1 0 0 1 1 1 0 SRS domain MarR_2 PF12802.2 AIF84964.1 - 1.4e-05 24.6 0.1 3.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 MarR family TPR_11 PF13414.1 AIF84964.1 - 0.00038 20.0 0.3 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 TPR repeat DUF4398 PF14346.1 AIF84964.1 - 0.001 19.1 3.3 0.001 19.1 2.3 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF4398) DUF4366 PF14283.1 AIF84964.1 - 0.0028 17.1 0.1 0.0067 15.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) HTH_IclR PF09339.5 AIF84964.1 - 0.0034 16.9 0.0 0.0098 15.4 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain TPR_12 PF13424.1 AIF84964.1 - 0.0035 17.2 1.3 0.012 15.5 0.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AIF84964.1 - 0.0041 17.7 0.9 2 9.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HTH_24 PF13412.1 AIF84964.1 - 0.0072 15.6 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 AIF84964.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TPR_2 PF07719.12 AIF84964.1 - 0.013 15.3 0.6 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 AIF84964.1 - 0.02 14.7 1.5 5.6 6.9 0.2 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain HTH_20 PF12840.2 AIF84964.1 - 0.085 12.6 0.1 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CBS PF00571.23 AIF84965.1 - 9.3e-19 66.9 3.4 9.2e-09 34.9 0.1 2.3 2 0 0 2 2 2 2 CBS domain zf-C2H2_4 PF13894.1 AIF84965.1 - 9.3e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF84965.1 - 0.00091 19.4 0.4 0.0019 18.4 0.0 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 AIF84965.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding fn3 PF00041.16 AIF84966.1 - 0.01 15.9 1.7 0.082 13.0 1.2 2.1 1 1 0 1 1 1 0 Fibronectin type III domain SusE PF14292.1 AIF84966.1 - 0.023 14.4 1.7 0.053 13.3 1.1 1.7 1 1 0 1 1 1 0 SusE outer membrane protein FlaE PF07559.9 AIF84966.1 - 0.032 14.8 7.3 0.086 13.5 1.5 2.1 1 1 1 2 2 2 0 Flagellar basal body protein FlaE Tissue_fac PF01108.12 AIF84966.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Tissue factor Flu_PB2 PF00604.12 AIF84966.1 - 0.042 11.7 0.1 0.047 11.5 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 DUF4330 PF14221.1 AIF84966.1 - 0.07 12.9 0.1 0.1 12.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4330) Prok-JAB PF14464.1 AIF84966.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain CarboxypepD_reg PF13620.1 AIF84966.1 - 0.75 9.8 3.7 0.53 10.3 0.8 2.0 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Lyase_1 PF00206.15 AIF84967.1 - 5e-45 154.0 0.1 5e-45 154.0 0.1 1.8 2 1 0 2 2 2 1 Lyase ADSL_C PF10397.4 AIF84967.1 - 8.9e-21 73.6 0.2 2e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pro-kuma_activ PF09286.6 AIF84967.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain ABM PF03992.11 AIF84968.1 - 0.0035 17.3 0.1 0.0075 16.2 0.0 1.7 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase RtcB PF01139.12 AIF84969.1 - 6.6e-148 493.1 0.0 7.4e-148 492.9 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB dsDNA_bind PF01984.15 AIF84970.1 - 0.0025 17.7 0.3 0.003 17.5 0.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S11 PF00411.14 AIF84972.1 - 4.7e-39 132.9 0.2 5.5e-39 132.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Methyltransf_11 PF08241.7 AIF84973.1 - 1.6e-11 44.5 0.0 2.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF84973.1 - 2.1e-07 30.6 0.0 2.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF84973.1 - 0.0029 18.1 0.0 0.0048 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF84973.1 - 0.0031 17.2 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF84973.1 - 0.0036 17.6 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF84973.1 - 0.0046 17.4 0.0 0.0075 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HATPase_c PF02518.21 AIF84976.1 - 3.5e-23 81.4 0.4 1.2e-22 79.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AIF84976.1 - 3.1e-14 52.6 0.2 8.4e-14 51.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 AIF84976.1 - 3e-09 37.1 0.0 7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 AIF84976.1 - 1.3e-05 25.2 0.0 4e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 PAS fold PAS PF00989.19 AIF84976.1 - 0.00062 19.5 0.0 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 AIF84976.1 - 0.019 14.8 0.0 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF2620 PF10941.3 AIF84976.1 - 0.051 13.6 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF2620 HATPase_c_3 PF13589.1 AIF84976.1 - 0.051 13.2 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AIF84976.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.19 AIF84977.1 - 4.4e-14 52.4 0.1 5.8e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain DUF2910 PF11139.3 AIF84979.1 - 0.61 9.1 12.0 5.2 6.1 8.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2910) Sina PF03145.11 AIF84980.1 - 0.081 12.5 0.2 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Seven in absentia protein family AIRS PF00586.19 AIF84981.1 - 5.5e-17 61.7 0.3 1.6e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.17 AIF84981.1 - 2e-08 34.3 0.1 3.1e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain PGM_PMM_I PF02878.11 AIF84982.1 - 1e-24 86.5 0.0 3.1e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AIF84982.1 - 1.5e-17 63.6 0.1 3.4e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AIF84982.1 - 1.6e-15 57.2 0.2 3.4e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AIF84982.1 - 1.3e-06 28.3 0.0 4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain P-II PF00543.17 AIF84983.1 - 4.2e-18 65.6 0.8 5.9e-18 65.2 0.5 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DEP PF00610.16 AIF84984.1 - 0.073 12.8 0.0 0.092 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cpn60_TCP1 PF00118.19 AIF84985.1 - 2.7e-164 547.3 10.4 3.1e-164 547.1 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FerA PF08165.6 AIF84986.1 - 0.033 13.8 0.2 0.04 13.5 0.2 1.2 1 0 0 1 1 1 0 FerA (NUC095) domain zf-C2H2_6 PF13912.1 AIF84987.1 - 0.00012 21.8 1.0 0.00015 21.5 0.7 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 AIF84987.1 - 0.0024 17.7 0.4 0.0027 17.6 0.2 1.1 1 0 0 1 1 1 1 Zinc ribbon domain DUF466 PF04328.8 AIF84987.1 - 0.014 15.1 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF466) zf-C2H2 PF00096.21 AIF84987.1 - 0.018 15.3 1.8 0.026 14.8 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF84987.1 - 0.2 12.0 1.9 0.28 11.5 1.3 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AIF84987.1 - 3 8.3 5.9 7.2 7.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 AIF84989.1 - 8e-05 22.7 1.2 0.0038 17.4 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AIF84989.1 - 0.024 14.5 0.4 0.042 13.7 0.1 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1644 PF07800.7 AIF84989.1 - 0.025 14.4 0.4 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zf-AD PF07776.10 AIF84989.1 - 0.053 13.5 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-C2H2 PF00096.21 AIF84989.1 - 0.074 13.4 0.5 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type MarC PF01914.12 AIF84994.1 - 2.7e-47 160.5 16.5 3.3e-47 160.2 11.4 1.1 1 0 0 1 1 1 1 MarC family integral membrane protein DUF4234 PF14018.1 AIF84994.1 - 5.2 6.8 6.7 0.5 10.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Hanta_G1 PF01567.11 AIF84997.1 - 0.31 9.2 1.4 0.33 9.1 0.9 1.0 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 TctB PF07331.6 AIF84997.1 - 0.52 9.9 5.1 11 5.6 3.8 1.9 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3185 PF11381.3 AIF84997.1 - 0.65 9.8 7.6 2.1 8.1 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Fst_toxin PF13955.1 AIF84997.1 - 1.4 8.6 5.6 2.5 7.8 3.9 1.4 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system Lung_7-TM_R PF06814.8 AIF84999.1 - 0.022 13.7 0.0 0.027 13.4 0.0 1.0 1 0 0 1 1 1 0 Lung seven transmembrane receptor DUF2142 PF09913.4 AIF84999.1 - 0.18 10.4 0.9 0.2 10.2 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF1469 PF07332.6 AIF85000.1 - 0.011 15.4 4.3 0.013 15.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF872 PF05915.7 AIF85000.1 - 0.016 15.0 1.1 0.017 14.9 0.8 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF2178 PF09946.4 AIF85000.1 - 0.15 11.8 0.5 0.23 11.2 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) GLTT PF01744.15 AIF85000.1 - 0.18 11.2 1.3 0.27 10.6 0.5 1.6 2 0 0 2 2 2 0 GLTT repeat (6 copies) ACT_6 PF13740.1 AIF85001.1 - 0.063 13.0 0.0 0.087 12.5 0.0 1.4 1 1 0 1 1 1 0 ACT domain HEAT_2 PF13646.1 AIF85002.1 - 0.089 13.0 0.2 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 HEAT repeats DUF2201_N PF13203.1 AIF85002.1 - 0.15 11.2 3.7 0.15 11.2 2.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 AIF85002.1 - 2.3 7.9 8.0 2.7 7.7 5.5 1.1 1 0 0 1 1 1 0 DDHD domain TATR PF03430.8 AIF85002.1 - 2.3 6.7 4.9 2.2 6.8 3.4 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator IATP PF04568.7 AIF85002.1 - 4.8 7.2 10.5 0.5 10.4 3.5 2.0 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP CitMHS PF03600.11 AIF85003.1 - 3.2e-37 127.9 38.9 4.4e-37 127.4 19.6 2.0 2 0 0 2 2 2 2 Citrate transporter ADH_N PF08240.7 AIF85004.1 - 1.3e-28 98.8 2.1 2.7e-28 97.8 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIF85004.1 - 3.9e-19 68.4 1.3 7.2e-19 67.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIF85004.1 - 1.5e-05 25.8 0.9 3.2e-05 24.8 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AIF85004.1 - 0.00021 20.4 0.1 0.00038 19.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.14 AIF85004.1 - 0.012 16.0 0.5 0.034 14.6 0.3 1.7 1 0 0 1 1 1 0 CoA binding domain Methyltransf_31 PF13847.1 AIF85004.1 - 0.013 15.0 0.1 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ELFV_dehydrog PF00208.16 AIF85004.1 - 0.013 15.0 0.4 0.022 14.3 0.3 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 AIF85004.1 - 0.016 14.7 0.2 0.044 13.3 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 AIF85004.1 - 0.1 13.1 0.1 0.43 11.1 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.23 AIF85005.1 - 8.2e-21 74.0 0.0 1.2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain TrmB PF01978.14 AIF85006.1 - 0.00097 18.8 0.7 0.002 17.8 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 AIF85006.1 - 0.0021 18.3 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain LexA_DNA_bind PF01726.11 AIF85006.1 - 0.0054 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 LexA DNA binding domain MgtC PF02308.11 AIF85008.1 - 6e-29 100.5 5.0 7.1e-29 100.3 3.5 1.1 1 0 0 1 1 1 1 MgtC family EI24 PF07264.6 AIF85008.1 - 0.035 13.5 0.7 0.05 13.0 0.5 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Chromate_transp PF02417.10 AIF85008.1 - 0.062 12.9 5.6 0.081 12.5 3.9 1.2 1 0 0 1 1 1 0 Chromate transporter Herpes_pp38 PF04846.8 AIF85008.1 - 1.4 8.2 4.7 12 5.3 0.4 2.6 1 1 1 2 2 2 0 Herpesvirus pp38 phosphoprotein AA_permease_C PF13906.1 AIF85008.1 - 2.5 8.0 5.2 1.4 8.8 0.6 2.6 3 0 0 3 3 3 0 C-terminus of AA_permease DUF3186 PF11382.3 AIF85008.1 - 2.7 7.0 5.9 2.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) MethyltransfD12 PF02086.10 AIF85009.1 - 4.5e-22 78.7 0.0 9.4e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 AIF85009.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TetR_N PF00440.18 AIF85010.1 - 1.3e-16 59.9 0.0 2.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.1 AIF85010.1 - 2.3e-07 30.8 0.0 6.3e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Bacterial transcriptional repressor tRNA-synt_2 PF00152.15 AIF85011.1 - 8.2e-77 258.2 0.0 9.9e-77 257.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AIF85011.1 - 8.9e-11 41.4 0.1 1.7e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 AIF85011.1 - 2.5e-05 23.8 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 tRNA_anti-like tRNA-synt_2d PF01409.15 AIF85011.1 - 0.12 11.5 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF2232 PF09991.4 AIF85012.1 - 0.036 13.0 9.5 0.016 14.2 3.6 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2232) TMEM192 PF14802.1 AIF85012.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 TMEM192 family Alba PF01918.16 AIF85013.1 - 0.015 14.9 0.7 0.04 13.4 0.3 1.9 1 1 1 2 2 2 0 Alba S-methyl_trans PF02574.11 AIF85014.1 - 2.8e-72 243.6 0.0 3.4e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase URO-D PF01208.12 AIF85014.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 1 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) DUF1822 PF08852.6 AIF85015.1 - 0.065 12.0 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) PSD2 PF07624.6 AIF85015.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Pterin_4a PF01329.14 AIF85018.1 - 1.4e-24 85.6 0.1 2.7e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase RskA PF10099.4 AIF85018.1 - 0.043 13.5 0.6 0.075 12.7 0.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DndB PF14072.1 AIF85020.1 - 0.018 14.2 0.2 0.021 14.0 0.2 1.3 1 1 0 1 1 1 0 DNA-sulfur modification-associated PAD_porph PF04371.10 AIF85020.1 - 0.095 11.7 0.3 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase Pterin_bind PF00809.17 AIF85021.1 - 1e-25 90.3 0.0 4.3e-25 88.3 0.0 2.0 2 0 0 2 2 2 1 Pterin binding enzyme Met_synt_B12 PF02965.12 AIF85021.1 - 9.4e-21 73.9 0.0 1.8e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding PF02310.14 AIF85021.1 - 4.3e-19 68.5 0.0 1.3e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.12 AIF85021.1 - 2.3e-16 59.5 0.1 6.5e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.11 AIF85021.1 - 4.3e-05 22.1 0.0 8.4e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Methylase_S PF01420.14 AIF85022.1 - 2.7e-37 128.3 0.0 6.6e-30 104.2 0.0 2.5 2 1 0 2 2 2 2 Type I restriction modification DNA specificity domain N6_Mtase PF02384.11 AIF85023.1 - 1.3e-63 214.9 0.0 3.7e-63 213.4 0.0 1.6 1 1 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.3 AIF85023.1 - 3.6e-17 63.0 0.4 3.6e-17 63.0 0.3 2.5 3 0 0 3 3 3 1 HsdM N-terminal domain Methyltransf_26 PF13659.1 AIF85023.1 - 2.4e-13 50.1 0.0 4.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AIF85023.1 - 3.9e-10 39.5 0.0 8.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 AIF85023.1 - 0.0001 21.9 0.1 0.0032 17.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Eco57I PF07669.6 AIF85023.1 - 0.00024 21.4 0.0 0.00064 20.0 0.0 1.7 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.9 AIF85023.1 - 0.006 15.9 0.1 0.038 13.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain DUF3961 PF13106.1 AIF85023.1 - 5.1 6.7 5.3 1 8.9 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3961) ResIII PF04851.10 AIF85024.1 - 2.6e-29 102.3 0.0 2.6e-29 102.3 0.0 2.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit EcoEI_R_C PF08463.5 AIF85024.1 - 4.2e-24 85.2 5.3 4.2e-24 85.2 3.7 2.4 3 0 0 3 3 2 1 EcoEI R protein C-terminal DEAD PF00270.24 AIF85024.1 - 3.5e-09 36.3 0.1 1.8e-08 34.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSDR_N PF04313.9 AIF85024.1 - 2.1e-08 34.1 5.0 8.4e-08 32.1 0.0 3.6 2 2 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Helicase_C PF00271.26 AIF85024.1 - 2.8e-06 27.1 0.0 7.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 AIF85024.1 - 0.00055 19.0 0.1 0.0017 17.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AIF85024.1 - 0.05 13.3 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 AIF85024.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 AIF85024.1 - 0.31 10.8 6.6 0.91 9.2 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function DUF87 DUF4446 PF14584.1 AIF85024.1 - 0.32 10.8 0.0 0.32 10.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) AAA_11 PF13086.1 AIF85024.1 - 1.4 8.4 0.0 1.4 8.4 0.0 2.9 2 2 1 3 3 3 0 AAA domain IncA PF04156.9 AIF85024.1 - 2 7.9 4.9 6 6.4 0.2 2.6 2 0 0 2 2 2 0 IncA protein TPR_11 PF13414.1 AIF85026.1 - 2.4e-27 94.3 24.1 1.8e-09 37.1 0.2 6.1 1 1 4 6 6 6 5 TPR repeat TPR_16 PF13432.1 AIF85026.1 - 6.6e-24 83.9 9.0 6.8e-05 23.4 0.1 7.4 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 AIF85026.1 - 3.1e-18 64.6 1.9 0.016 15.8 0.0 7.2 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 AIF85026.1 - 1.4e-17 63.7 9.5 3.5e-06 27.2 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 AIF85026.1 - 1.8e-17 61.7 35.4 1.4e-06 27.7 0.4 8.5 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 AIF85026.1 - 1.3e-16 59.3 36.1 2.4e-05 23.7 0.7 8.3 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 AIF85026.1 - 3.5e-16 57.6 7.8 9.5e-05 21.9 0.3 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 AIF85026.1 - 3.3e-14 51.8 12.6 0.056 13.6 0.1 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 AIF85026.1 - 4e-13 49.3 10.4 7.4e-05 22.8 0.1 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AIF85026.1 - 5.4e-13 48.5 1.4 3.2e-05 23.6 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AIF85026.1 - 9.3e-12 44.7 18.3 0.0005 19.9 0.2 6.1 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 AIF85026.1 - 1.5e-10 40.0 19.1 9.9e-06 24.9 0.4 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AIF85026.1 - 2.1e-07 30.6 15.6 0.016 15.0 0.2 7.3 7 1 1 8 8 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AIF85026.1 - 7.8e-07 29.1 14.9 0.0015 18.8 0.2 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 AIF85026.1 - 0.00052 19.1 0.5 0.012 14.7 0.0 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 AIF85026.1 - 0.0084 15.9 13.0 0.33 10.8 0.8 4.5 5 1 0 5 5 5 2 MIT (microtubule interacting and transport) domain BTAD PF03704.12 AIF85026.1 - 0.0093 16.2 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 AIF85026.1 - 0.031 14.2 8.1 2 8.4 0.4 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 AIF85026.1 - 0.036 13.2 0.9 1.9 7.5 0.1 3.1 1 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP PPR PF01535.15 AIF85026.1 - 0.34 10.9 10.4 13 6.0 0.0 5.4 6 1 0 6 6 5 0 PPR repeat Hjc PF01870.13 AIF85028.1 - 0.0027 17.2 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) NERD PF08378.6 AIF85028.1 - 0.06 13.6 0.1 0.095 12.9 0.1 1.4 1 0 0 1 1 1 0 Nuclease-related domain DUF234 PF03008.9 AIF85028.1 - 0.1 12.7 0.3 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function Peptidase_S8 PF00082.17 AIF85029.1 - 1.2e-17 64.0 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF1053 PF06327.9 AIF85029.1 - 0.083 13.2 0.5 0.26 11.6 0.2 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) Phage_integrase PF00589.17 AIF85030.1 - 4.4e-06 26.4 1.1 1.6e-05 24.6 0.2 2.4 1 1 1 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.1 AIF85030.1 - 0.0013 19.0 1.7 0.0068 16.7 0.1 2.6 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 AIF85030.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3098 PF11297.3 AIF85031.1 - 0.0063 16.1 0.4 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3098) IncA PF04156.9 AIF85031.1 - 0.007 15.9 0.9 0.074 12.6 0.2 2.1 2 0 0 2 2 2 1 IncA protein Neurensin PF14927.1 AIF85031.1 - 0.016 14.5 0.1 1.1 8.5 0.1 2.2 2 0 0 2 2 2 0 Neurensin Big_3 PF07523.7 AIF85031.1 - 0.034 14.2 0.0 0.53 10.3 0.0 2.2 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) ABC_tran PF00005.22 AIF85032.1 - 5.7e-32 110.8 0.0 8.4e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF85032.1 - 3.8e-10 40.2 0.0 0.00058 19.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain DUF258 PF03193.11 AIF85032.1 - 2.9e-05 23.3 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 AIF85032.1 - 4.7e-05 22.7 0.3 0.018 14.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AIF85032.1 - 5.4e-05 23.2 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 AIF85032.1 - 0.00028 20.0 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 AIF85032.1 - 0.00048 20.3 0.5 0.0067 16.6 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AIF85032.1 - 0.00053 19.4 0.2 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 AIF85032.1 - 0.00094 19.9 0.2 0.0021 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIF85032.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIF85032.1 - 0.0043 17.1 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 AIF85032.1 - 0.0096 14.6 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 AIF85032.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 AIF85032.1 - 0.011 14.3 0.0 0.053 12.0 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 AIF85032.1 - 0.012 15.3 0.0 0.041 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AIF85032.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AIF85032.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 AIF85032.1 - 0.016 15.5 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AIF85032.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AIF85032.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AIF85032.1 - 0.026 14.0 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 AIF85032.1 - 0.03 14.4 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 AIF85032.1 - 0.035 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 AIF85032.1 - 0.045 13.5 0.0 0.23 11.2 0.0 2.1 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 AIF85032.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 AIF85032.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 AIF85032.1 - 0.057 12.6 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Miro PF08477.8 AIF85032.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein SbcCD_C PF13558.1 AIF85032.1 - 0.076 12.9 0.4 0.37 10.7 0.3 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 AIF85032.1 - 0.093 12.1 0.4 0.5 9.7 0.0 1.9 1 1 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 AIF85032.1 - 0.099 12.6 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 AIF85032.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AIF85032.1 - 0.11 11.6 0.1 0.84 8.7 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MTHFR PF02219.12 AIF85033.1 - 0.00031 19.9 0.0 0.00056 19.0 0.0 1.5 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase IncA PF04156.9 AIF85035.1 - 0.077 12.5 1.0 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 IncA protein zf-Sec23_Sec24 PF04810.10 AIF85036.1 - 0.00054 19.4 4.0 0.0011 18.4 2.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-HIT PF04438.11 AIF85036.1 - 0.0033 17.0 6.7 0.0095 15.5 1.8 2.2 2 0 0 2 2 2 1 HIT zinc finger DZR PF12773.2 AIF85036.1 - 0.038 13.7 6.5 0.75 9.6 4.8 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF164 PF02591.10 AIF85036.1 - 0.044 13.6 4.3 0.069 12.9 3.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-C3HC4_3 PF13920.1 AIF85036.1 - 0.048 13.3 1.7 0.048 13.3 1.2 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L7Ae PF01248.21 AIF85036.1 - 0.055 12.9 0.3 0.059 12.8 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zinc-ribbons_6 PF07191.7 AIF85036.1 - 0.072 12.8 5.5 0.96 9.2 0.8 2.1 1 1 1 2 2 2 0 zinc-ribbons zf-FPG_IleRS PF06827.9 AIF85036.1 - 0.15 11.7 6.1 5.1 6.8 0.2 2.8 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-ribbon_3 PF13248.1 AIF85036.1 - 0.17 11.1 4.7 5.1 6.4 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.3 AIF85036.1 - 0.21 11.5 4.5 0.28 11.1 0.8 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PolC_DP2 PF03833.8 AIF85036.1 - 0.72 7.4 3.7 0.77 7.3 2.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Opy2 PF09463.5 AIF85036.1 - 0.9 9.6 5.9 1.4 9.0 1.3 2.3 2 0 0 2 2 2 0 Opy2 protein Stc1 PF12898.2 AIF85036.1 - 2.5 8.2 5.6 6.9 6.8 3.9 1.8 1 1 0 1 1 1 0 Stc1 domain RecR PF02132.10 AIF85036.1 - 2.5 7.5 7.6 5.2 6.5 1.4 2.3 2 0 0 2 2 2 0 RecR protein C1_1 PF00130.17 AIF85036.1 - 3.2 7.5 8.3 17 5.2 5.8 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 AIF85036.1 - 3.5 7.5 6.7 9.5 6.1 4.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger Ribosomal_L32p PF01783.18 AIF85036.1 - 5.5 7.2 7.4 2.9 8.1 0.8 2.1 1 1 1 2 2 2 0 Ribosomal L32p protein family zf-MYND PF01753.13 AIF85036.1 - 5.5 6.9 8.3 29 4.6 5.2 2.2 1 1 0 1 1 1 0 MYND finger ZZ PF00569.12 AIF85036.1 - 5.5 6.6 6.8 39 3.8 4.7 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type DUF1610 PF07754.6 AIF85036.1 - 9.2 6.4 7.8 1.6 8.9 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-RING-like PF08746.6 AIF85036.1 - 9.4 6.3 9.8 2.1 8.4 3.6 1.9 2 0 0 2 2 2 0 RING-like domain MEDS PF14417.1 AIF85038.1 - 9.5e-06 24.7 0.2 1.7e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Glyco_transf_54 PF04666.8 AIF85038.1 - 0.096 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4415 PF14384.1 AIF85039.1 - 0.1 12.7 0.0 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4415) Usp PF00582.21 AIF85040.1 - 1.1e-31 109.9 0.1 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family NUDIX PF00293.23 AIF85042.1 - 2.4e-12 46.6 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Rot1 PF10681.4 AIF85043.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Cytochrom_B_N PF00033.14 AIF85045.1 - 0.073 12.4 0.1 0.084 12.2 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF1918 PF08940.6 AIF85046.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) FNIP_N PF14636.1 AIF85047.1 - 0.057 13.8 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus GCD14 PF08704.5 AIF85048.1 - 1.3e-36 126.4 0.0 5.8e-34 117.6 0.0 2.1 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 AIF85048.1 - 1.3e-09 37.8 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AIF85048.1 - 1.5e-09 37.6 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF85048.1 - 1.4e-08 35.3 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF85048.1 - 7.9e-08 32.3 0.0 6.7e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF85048.1 - 1.8e-06 27.2 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 AIF85048.1 - 1.3e-05 24.3 0.0 2.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 AIF85048.1 - 0.00021 21.5 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 AIF85048.1 - 0.00027 21.7 0.0 0.00048 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF85048.1 - 0.00047 20.5 0.0 0.0009 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2827 PF10933.3 AIF85048.1 - 0.0024 16.4 0.0 0.0029 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2827) UPF0020 PF01170.13 AIF85048.1 - 0.0025 17.4 0.0 0.0064 16.0 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 AIF85048.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF85048.1 - 0.0056 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.12 AIF85048.1 - 0.007 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin PrmA PF06325.8 AIF85048.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_21 PF05050.7 AIF85048.1 - 0.023 14.6 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase FkbM domain RrnaAD PF00398.15 AIF85048.1 - 0.038 13.0 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 AIF85048.1 - 0.043 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Gcd10p PF04189.8 AIF85048.1 - 0.072 12.2 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Gcd10p family tRNA-synt_1d PF00750.14 AIF85051.1 - 1.5e-38 132.5 1.0 2.6e-29 102.1 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 AIF85051.1 - 2.7e-30 104.7 1.6 2.7e-30 104.7 1.1 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AIF85051.1 - 3.7e-15 56.2 0.0 1.6e-14 54.2 0.0 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.6 AIF85051.1 - 0.0025 16.5 0.5 0.017 13.8 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (M) Hydrolase_3 PF08282.7 AIF85052.1 - 9.3e-26 90.9 0.0 2e-17 63.6 0.1 2.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIF85052.1 - 3.7e-07 30.7 0.4 0.00029 21.3 0.1 2.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AIF85052.1 - 1.6e-05 24.3 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AIF85052.1 - 4.2e-05 23.7 0.0 0.041 14.0 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AIF85052.1 - 0.0024 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like LNS2 PF08235.8 AIF85052.1 - 0.068 12.7 0.1 0.17 11.4 0.1 1.8 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Hydrolase_6 PF13344.1 AIF85052.1 - 0.13 12.2 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pyrophosphatase PF00719.14 AIF85053.1 - 4e-60 201.7 1.7 4.6e-60 201.5 1.2 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase RNaseH_C PF09293.5 AIF85053.1 - 0.024 14.5 0.7 0.057 13.3 0.4 1.7 1 1 0 1 1 1 0 T4 RNase H, C terminal CHB_HEX_C PF03174.8 AIF85054.1 - 8.2e-36 121.6 30.8 6.2e-21 74.0 1.8 3.9 5 0 0 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 AIF85054.1 - 3e-31 107.3 22.5 3.6e-16 58.9 2.9 3.5 3 0 0 3 3 3 2 Fn3 associated CHB_HEX_C_1 PF13290.1 AIF85054.1 - 7.9e-28 96.0 34.2 1.4e-16 60.0 3.5 4.4 4 1 1 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain Polysacc_deac_1 PF01522.16 AIF85054.1 - 8.4e-11 41.5 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase HYR PF02494.11 AIF85054.1 - 4.6e-06 26.5 15.7 0.001 19.0 0.8 4.9 4 1 0 4 4 4 2 HYR domain Gmad2 PF10648.4 AIF85054.1 - 0.00012 22.1 1.1 0.0069 16.5 0.1 3.4 3 0 0 3 3 3 1 Immunoglobulin-like domain of bacterial spore germination Glyco_hydro_57 PF03065.10 AIF85054.1 - 0.0032 16.4 0.0 0.0056 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Y_Y_Y PF07495.8 AIF85054.1 - 0.0053 16.4 0.1 0.018 14.7 0.1 1.9 1 0 0 1 1 1 1 Y_Y_Y domain Transglut_C PF00927.17 AIF85054.1 - 0.0054 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family, C-terminal ig like domain Big_3_4 PF13754.1 AIF85054.1 - 0.0064 16.7 5.9 0.0064 16.7 4.1 7.0 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 3) Mo-co_dimer PF03404.11 AIF85054.1 - 0.043 13.4 0.1 0.23 11.0 0.0 2.2 1 1 1 2 2 2 0 Mo-co oxidoreductase dimerisation domain AAA PF00004.24 AIF85055.1 - 4.8e-37 127.1 0.0 2.3e-36 124.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 AIF85055.1 - 6.4e-08 32.3 4.7 9.2e-08 31.8 2.2 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 AIF85055.1 - 1.1e-05 25.5 0.1 0.00023 21.3 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 AIF85055.1 - 3.7e-05 23.6 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AIF85055.1 - 7.5e-05 22.7 0.1 0.00074 19.5 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 AIF85055.1 - 9.3e-05 22.3 0.0 0.00049 19.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 AIF85055.1 - 0.00013 22.7 0.0 0.00098 19.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AIF85055.1 - 0.00018 20.9 0.3 0.006 16.0 0.1 2.4 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AIF85055.1 - 0.0002 20.4 0.0 0.0004 19.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 AIF85055.1 - 0.0005 19.2 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 AIF85055.1 - 0.00061 19.9 0.1 0.097 12.8 0.0 2.7 2 1 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 AIF85055.1 - 0.0015 18.2 0.0 0.028 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 AIF85055.1 - 0.0021 17.9 0.1 0.0092 15.8 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_19 PF13245.1 AIF85055.1 - 0.0041 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 AIF85055.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AIF85055.1 - 0.0067 16.0 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AIF85055.1 - 0.0097 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TPR_11 PF13414.1 AIF85055.1 - 0.01 15.4 0.9 0.025 14.1 0.6 1.7 1 0 0 1 1 1 1 TPR repeat AAA_18 PF13238.1 AIF85055.1 - 0.014 15.6 0.0 0.042 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 AIF85055.1 - 0.017 14.1 0.0 0.14 11.1 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.16 AIF85055.1 - 0.021 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 AIF85055.1 - 0.028 13.1 0.0 0.064 11.9 0.0 1.6 1 1 1 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 AIF85055.1 - 0.061 13.0 0.0 0.58 9.8 0.0 2.2 2 1 1 3 3 2 0 Archaeal ATPase KaiC PF06745.8 AIF85055.1 - 0.091 11.8 0.0 1.2 8.2 0.0 2.5 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 AIF85055.1 - 0.11 11.7 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 AIF85055.1 - 0.12 12.7 0.1 1 9.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 AIF85055.1 - 0.12 12.0 0.0 0.81 9.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 AIF85055.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrmB PF01978.14 AIF85058.1 - 2.6e-16 59.0 1.0 5.1e-16 58.1 0.2 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AIF85058.1 - 0.0039 16.1 0.0 0.0083 15.1 0.0 1.5 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB MarR_2 PF12802.2 AIF85058.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 AIF85058.1 - 0.091 12.1 0.3 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF192 PF02643.10 AIF85059.1 - 4.8e-29 100.2 0.0 6.8e-29 99.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 tRNA-synt_1 PF00133.17 AIF85060.1 - 7.5e-137 456.8 0.0 1.1e-136 456.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AIF85060.1 - 2e-27 95.8 0.1 5.7e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AIF85060.1 - 2.5e-23 82.4 0.8 6.8e-10 38.1 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AIF85060.1 - 1.2e-05 24.5 0.0 0.00011 21.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 AIF85060.1 - 0.00015 20.5 0.0 0.00036 19.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (K) Lar_restr_allev PF14354.1 AIF85060.1 - 0.02 15.1 0.3 0.85 9.9 0.0 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 AIF85060.1 - 0.18 11.7 3.5 0.46 10.4 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 AIF85060.1 - 1 8.9 7.5 2.1 7.9 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 AIF85060.1 - 1.2 9.0 3.4 38 4.2 0.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon SPAM PF02090.10 AIF85062.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein RHH_1 PF01402.16 AIF85062.1 - 0.14 12.1 2.5 0.15 12.0 0.3 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Rieske PF00355.21 AIF85063.1 - 3.3e-17 61.8 0.1 4.5e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AIF85063.1 - 1.2e-09 37.7 0.0 1.9e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain PQQ_2 PF13360.1 AIF85063.1 - 0.11 11.9 0.0 8.6 5.7 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain FTP PF07504.8 AIF85063.1 - 0.15 11.5 0.6 9.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif DSPc PF00782.15 AIF85065.1 - 2.7e-17 62.5 0.0 3.5e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 AIF85065.1 - 3.4e-07 30.4 0.0 5.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 AIF85065.1 - 4.4e-07 29.4 0.0 5.7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AIF85065.1 - 5.8e-06 26.6 0.1 1.1e-05 25.8 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 AIF85065.1 - 0.0031 16.8 0.0 0.0067 15.7 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF899 PF05988.7 AIF85066.1 - 1.8e-77 259.5 0.4 2.3e-77 259.1 0.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 AIF85066.1 - 4.2e-05 23.2 0.0 6.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 3-dmu-9_3-mt PF06983.8 AIF85067.1 - 5.4e-05 23.4 0.0 5.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase TF_Zn_Ribbon PF08271.7 AIF85068.1 - 0.00018 20.7 1.1 0.00024 20.3 0.7 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 AIF85068.1 - 0.0013 18.1 1.0 0.0021 17.4 0.7 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 AIF85068.1 - 0.0027 16.8 3.9 0.013 14.7 2.7 1.9 1 1 1 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIF85068.1 - 0.0046 16.6 2.2 0.019 14.6 1.5 1.9 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF85068.1 - 0.0047 16.4 2.7 0.012 15.1 1.9 1.7 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AIF85068.1 - 0.0054 16.5 0.8 0.0077 16.0 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon Prok-RING_1 PF14446.1 AIF85068.1 - 0.0083 15.8 1.4 0.013 15.2 0.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Ribosomal_S27e PF01667.12 AIF85068.1 - 0.018 14.5 0.4 0.024 14.1 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S27 OrfB_Zn_ribbon PF07282.6 AIF85068.1 - 0.02 14.5 1.7 0.028 14.0 1.1 1.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 AIF85068.1 - 0.022 15.0 1.6 0.37 11.1 1.1 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-H2C2_2 PF13465.1 AIF85068.1 - 0.023 14.9 3.7 3.2 8.2 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain DUF2387 PF09526.5 AIF85068.1 - 0.03 14.2 1.8 0.045 13.6 1.2 1.3 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) HypA PF01155.14 AIF85068.1 - 0.031 13.9 0.3 0.033 13.8 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family IBR PF01485.16 AIF85068.1 - 0.033 14.0 1.0 0.052 13.4 0.7 1.3 1 0 0 1 1 1 0 IBR domain zinc-ribbons_6 PF07191.7 AIF85068.1 - 0.045 13.5 0.4 0.055 13.2 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons RNA_POL_M_15KD PF02150.11 AIF85068.1 - 0.052 13.2 0.7 0.1 12.3 0.5 1.5 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Mu-like_Com PF10122.4 AIF85068.1 - 0.06 12.4 0.1 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com UPF0547 PF10571.4 AIF85068.1 - 0.068 12.8 5.4 0.91 9.2 3.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 YyzF PF14116.1 AIF85068.1 - 0.068 13.1 4.1 0.11 12.4 0.2 2.1 1 1 1 2 2 2 0 YyzF-like protein CpXC PF14353.1 AIF85068.1 - 0.075 12.9 1.8 1.5 8.7 0.1 2.1 1 1 1 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.5 AIF85068.1 - 0.078 12.9 4.1 0.42 10.6 2.8 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-CCHC_5 PF14787.1 AIF85068.1 - 0.084 12.3 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C4_ClpX PF06689.8 AIF85068.1 - 0.089 12.3 0.3 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 ClpX C4-type zinc finger DUF2225 PF09986.4 AIF85068.1 - 0.089 12.2 0.8 0.21 11.0 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2082 PF09855.4 AIF85068.1 - 0.11 12.2 5.7 1.7 8.5 0.3 2.2 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Ogr_Delta PF04606.7 AIF85068.1 - 0.12 12.0 0.9 1.8 8.2 0.2 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger A2L_zn_ribbon PF08792.5 AIF85068.1 - 0.12 11.8 2.1 5.4 6.6 1.5 2.3 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF329 PF03884.9 AIF85068.1 - 0.13 11.8 1.7 1 8.9 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF329) zf-C2H2_4 PF13894.1 AIF85068.1 - 0.14 12.5 0.8 9.5 6.8 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_2 PF13240.1 AIF85068.1 - 0.19 11.2 5.6 0.94 9.0 3.9 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 AIF85068.1 - 0.21 11.3 1.1 0.71 9.6 0.7 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-TFIIB PF13453.1 AIF85068.1 - 0.28 10.4 1.4 0.4 9.9 1.0 1.3 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-ISL3 PF14690.1 AIF85068.1 - 0.29 11.1 3.7 1.2 9.2 1.7 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rubredoxin PF00301.15 AIF85068.1 - 0.6 10.0 3.0 9 6.2 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin Zn_Tnp_IS1595 PF12760.2 AIF85068.1 - 0.83 9.5 4.6 4.6 7.1 0.6 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-HIT PF04438.11 AIF85068.1 - 0.84 9.3 5.8 9.4 5.9 0.1 2.1 2 0 0 2 2 2 0 HIT zinc finger Auto_anti-p27 PF06677.7 AIF85068.1 - 0.98 9.2 4.9 0.79 9.5 0.4 2.3 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TFIIS_C PF01096.13 AIF85068.1 - 1.7 8.3 4.0 1.4 8.6 0.5 2.0 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2 PF00096.21 AIF85068.1 - 4 7.9 5.3 13 6.3 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_S6e PF01092.14 AIF85069.1 - 8.5e-19 67.4 1.0 1.2e-18 66.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e GTP_EFTU PF00009.22 AIF85070.1 - 2.8e-41 141.0 0.0 4.4e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AIF85070.1 - 1.8e-27 95.2 0.6 4.8e-27 93.8 0.1 1.9 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AIF85070.1 - 0.00069 19.6 0.9 0.0017 18.4 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AIF85070.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.9 1 1 1 2 2 2 0 50S ribosome-binding GTPase Fcf1 PF04900.7 AIF85071.1 - 2.1e-09 37.3 0.0 2.6e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Fcf1 DUF188 PF02639.9 AIF85071.1 - 0.02 14.3 0.3 0.026 13.9 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 PIN PF01850.16 AIF85071.1 - 0.025 14.9 0.4 0.075 13.3 0.3 1.7 1 1 0 1 1 1 0 PIN domain PIN_4 PF13638.1 AIF85071.1 - 0.028 14.5 0.2 0.067 13.3 0.2 1.7 1 1 0 1 1 1 0 PIN domain Lactamase_B_3 PF13483.1 AIF85072.1 - 1.5e-31 109.2 1.0 1.9e-31 109.0 0.7 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 AIF85072.1 - 2.3e-20 72.9 0.0 2.9e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AIF85072.1 - 0.016 14.8 0.8 0.66 9.5 0.5 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Pro_isomerase PF00160.16 AIF85073.1 - 6.4e-48 162.8 0.1 1.1e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD STT3 PF02516.9 AIF85073.1 - 2.1e-42 145.7 30.5 3.1e-42 145.1 21.1 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 AIF85073.1 - 1.4e-07 31.5 17.4 1.4e-07 31.5 12.1 3.3 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Inositol_P PF00459.20 AIF85074.1 - 1.2e-49 169.0 0.0 1.3e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 AIF85074.1 - 0.0096 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase SnoaL_2 PF12680.2 AIF85075.1 - 2.2e-08 34.4 0.0 2.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AIF85075.1 - 3.4e-06 27.2 0.0 3.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 AIF85075.1 - 1.2e-05 25.2 0.1 3.2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain Tap-RNA_bind PF09162.5 AIF85075.1 - 0.066 12.7 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Tap, RNA-binding SnoaL_4 PF13577.1 AIF85075.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.15 AIF85075.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DS PF01916.12 AIF85076.1 - 2.9e-75 253.1 0.0 3.4e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DS PF01916.12 AIF85078.1 - 2.1e-50 171.5 0.0 2.6e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase LigT_PEase PF02834.11 AIF85080.1 - 3.3e-22 78.2 0.0 1.2e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 AIF85080.1 - 6.3e-12 45.4 0.0 7.5e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.4 AIF85080.1 - 7.9e-09 35.5 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF2680 PF10925.3 AIF85080.1 - 0.027 14.3 0.4 6.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) tRNA_NucTransf2 PF09249.6 AIF85081.1 - 7.5e-37 125.6 0.0 1.5e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.18 AIF85081.1 - 1.4e-10 41.3 0.0 2.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Choline_kinase PF01633.15 AIF85082.1 - 0.0074 15.8 0.1 0.15 11.5 0.0 2.1 1 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 AIF85082.1 - 0.028 14.1 0.2 0.39 10.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PAC2 PF09754.4 AIF85083.1 - 2.1e-28 99.6 0.0 2.6e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 PAC2 family HhH-GPD PF00730.20 AIF85084.1 - 1.6e-17 63.7 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_L2_C PF03947.13 AIF85086.1 - 1.6e-35 121.7 1.8 2.6e-35 121.0 1.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AIF85086.1 - 7.2e-11 41.9 0.1 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Glyoxalase_2 PF12681.2 AIF85087.1 - 2.1e-14 54.0 0.0 2.8e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF85087.1 - 8.8e-08 32.1 0.0 1.5e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NIR_SIR PF01077.17 AIF85088.1 - 6.5e-42 142.5 0.1 1.5e-29 102.3 0.0 2.6 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 AIF85088.1 - 1.5e-33 114.2 0.1 8.5e-19 66.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Rhodanese PF00581.15 AIF85089.1 - 6.1e-36 123.2 0.0 1.1e-16 61.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain OrfB_IS605 PF01385.14 AIF85090.1 - 5.2e-28 97.9 4.1 7.3e-28 97.5 2.8 1.1 1 0 0 1 1 1 1 Probable transposase OrfB_Zn_ribbon PF07282.6 AIF85090.1 - 4e-21 74.4 0.1 8.4e-21 73.4 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.3 AIF85090.1 - 3e-10 39.2 0.4 3e-10 39.2 0.3 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain RRXRR PF14239.1 AIF85090.1 - 0.017 14.5 1.0 0.034 13.5 0.7 1.5 1 0 0 1 1 1 0 RRXRR protein DUF1451 PF07295.6 AIF85090.1 - 0.074 12.8 0.6 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Zn_Tnp_IS1595 PF12760.2 AIF85090.1 - 0.11 12.3 0.9 0.23 11.2 0.6 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TMF_DNA_bd PF12329.3 AIF85091.1 - 0.011 15.4 0.9 0.038 13.7 0.6 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_18 PF13238.1 AIF85092.1 - 4.9e-15 55.9 0.2 1.1e-14 54.8 0.1 1.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 AIF85092.1 - 5.5e-12 46.5 0.0 7.8e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 AIF85092.1 - 5.6e-06 26.3 0.2 6.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 AIF85092.1 - 6.4e-05 22.8 0.2 0.0003 20.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 AIF85092.1 - 0.00013 21.4 0.2 0.0005 19.5 0.0 1.8 1 1 1 2 2 2 1 Dephospho-CoA kinase AAA_28 PF13521.1 AIF85092.1 - 0.00032 20.6 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 AIF85092.1 - 0.00073 19.2 0.1 0.003 17.2 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 AIF85092.1 - 0.00074 18.6 0.1 0.0023 17.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 AIF85092.1 - 0.0012 18.9 0.1 0.0022 18.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AIF85092.1 - 0.0019 18.5 0.3 0.0063 16.8 0.2 1.8 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 AIF85092.1 - 0.0039 16.0 0.0 0.0066 15.2 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_14 PF13173.1 AIF85092.1 - 0.0053 16.6 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIF85092.1 - 0.0055 16.7 0.1 0.0077 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 AIF85092.1 - 0.0078 15.8 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Torsin PF06309.6 AIF85092.1 - 0.0093 15.8 0.0 0.045 13.6 0.0 1.9 1 1 1 2 2 2 1 Torsin KTI12 PF08433.5 AIF85092.1 - 0.011 14.9 0.1 0.02 14.1 0.1 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 AIF85092.1 - 0.017 13.9 0.1 0.023 13.5 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 AIF85092.1 - 0.023 14.4 0.3 0.08 12.6 0.2 2.0 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.9 AIF85092.1 - 0.055 13.1 0.1 0.1 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 AIF85092.1 - 0.096 12.7 0.1 0.23 11.4 0.0 1.8 2 1 0 2 2 2 0 Sigma-54 interaction domain B12-binding PF02310.14 AIF85092.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain AAA_19 PF13245.1 AIF85092.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Cytidylate_kin2 PF13189.1 AIF85092.1 - 0.14 12.0 0.4 5.9 6.7 0.3 2.7 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_binding PF01877.12 AIF85093.1 - 5.3e-15 55.4 0.0 8.7e-15 54.7 0.0 1.3 1 1 0 1 1 1 1 RNA binding GFA PF04828.9 AIF85094.1 - 0.003 17.4 1.9 0.0063 16.4 1.3 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HypA PF01155.14 AIF85094.1 - 0.0065 16.1 0.5 0.0067 16.0 0.4 1.0 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-NADH-PPase PF09297.6 AIF85094.1 - 0.0086 15.5 0.3 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.7 AIF85094.1 - 0.016 14.9 4.0 0.029 14.1 0.3 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ISL3 PF14690.1 AIF85094.1 - 0.016 15.1 3.9 0.085 12.9 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 AIF85094.1 - 0.025 14.4 4.5 0.041 13.7 3.1 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF85094.1 - 0.026 13.7 3.2 0.18 11.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF85094.1 - 0.028 13.8 5.4 0.36 10.3 3.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-IS66 PF13005.2 AIF85094.1 - 0.088 12.7 1.8 0.13 12.2 0.2 1.8 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-C4_Topoisom PF01396.14 AIF85094.1 - 0.098 12.1 0.2 0.098 12.1 0.1 2.1 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF3795 PF12675.2 AIF85094.1 - 0.14 12.3 1.8 0.15 12.2 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-A20 PF01754.11 AIF85094.1 - 0.19 11.3 2.4 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 A20-like zinc finger DUF2072 PF09845.4 AIF85094.1 - 0.44 10.4 3.1 0.85 9.5 2.1 1.5 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zinc_ribbon_4 PF13717.1 AIF85094.1 - 0.44 10.2 8.6 3.9 7.2 5.9 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-TFIIB PF13453.1 AIF85094.1 - 0.46 9.7 2.0 1.3 8.3 0.1 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger Cys_rich_KTR PF14205.1 AIF85094.1 - 0.5 9.8 4.0 5.6 6.4 0.2 2.2 2 0 0 2 2 2 0 Cysteine-rich KTR zinc_ribbon_5 PF13719.1 AIF85094.1 - 0.52 9.9 8.3 5.6 6.6 5.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AIF85094.1 - 0.57 9.5 2.6 1.7 8.0 0.3 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RanBP PF00641.13 AIF85094.1 - 0.63 9.1 5.7 3.5 6.8 0.4 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF2082 PF09855.4 AIF85094.1 - 0.66 9.8 4.5 1.9 8.4 0.1 2.1 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2387 PF09526.5 AIF85094.1 - 0.72 9.8 5.5 0.72 9.8 0.2 2.0 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) IBR PF01485.16 AIF85094.1 - 0.75 9.7 3.9 5.9 6.8 2.7 1.9 1 1 0 1 1 1 0 IBR domain DNA_RNApol_7kD PF03604.8 AIF85094.1 - 0.83 9.1 4.3 9.2 5.8 0.3 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ADK_lid PF05191.9 AIF85094.1 - 0.87 9.3 6.8 4.6 6.9 4.7 2.2 1 1 0 1 1 1 0 Adenylate kinase, active site lid Ornatin PF02088.10 AIF85094.1 - 0.95 9.0 6.3 1.3 8.6 4.4 1.3 1 0 0 1 1 1 0 Ornatin Zn-ribbon_8 PF09723.5 AIF85094.1 - 1 9.3 4.2 8.8 6.3 2.9 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-dskA_traR PF01258.12 AIF85094.1 - 1.3 8.8 4.2 13 5.6 0.3 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn_Tnp_IS1595 PF12760.2 AIF85094.1 - 2.1 8.2 4.6 1.2 8.9 0.3 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-CCHC_5 PF14787.1 AIF85094.1 - 2.5 7.6 7.1 0.96 8.9 0.6 2.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger ABC_tran PF00005.22 AIF85095.1 - 1.2e-32 113.0 0.0 2e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF85095.1 - 9.5e-12 45.4 0.0 5e-08 33.2 0.0 2.4 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 AIF85095.1 - 5.6e-05 23.2 0.1 0.00016 21.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 AIF85095.1 - 0.00041 19.5 0.0 0.038 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AIF85095.1 - 0.00046 19.6 0.2 0.00088 18.7 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.17 AIF85095.1 - 0.0014 18.0 0.3 0.0027 17.1 0.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 AIF85095.1 - 0.0018 18.6 0.8 0.0024 18.2 0.6 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AIF85095.1 - 0.002 18.2 0.2 0.049 13.8 0.2 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 AIF85095.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4162 PF13732.1 AIF85095.1 - 0.049 14.1 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_19 PF13245.1 AIF85095.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 AIF85095.1 - 0.098 13.1 0.1 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 AIF85095.1 - 0.11 12.0 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 AIF85095.1 - 0.21 11.5 0.8 0.63 9.9 0.1 2.1 2 1 1 3 3 3 0 AAA domain ABC2_membrane PF01061.19 AIF85096.1 - 7.8e-38 129.7 22.8 9.2e-38 129.5 15.8 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AIF85096.1 - 9.6e-16 57.7 28.5 9.6e-16 57.7 19.8 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 AIF85096.1 - 6e-07 28.6 25.0 5.7e-06 25.3 17.3 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 AIF85096.1 - 1.9e-06 27.2 25.1 2.3e-06 26.9 17.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Abhydrolase_6 PF12697.2 AIF85097.1 - 2.9e-30 105.8 0.0 3.3e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AIF85097.1 - 1e-12 47.9 0.0 2.5e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIF85097.1 - 1.3e-12 47.7 0.0 4e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 AIF85097.1 - 8.1e-05 22.9 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 AIF85097.1 - 0.0013 18.3 0.0 0.017 14.7 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 AIF85097.1 - 0.0019 17.6 0.0 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.9 AIF85097.1 - 0.0027 16.2 0.0 0.18 10.2 0.0 2.1 2 0 0 2 2 2 1 Ndr family Abhydrolase_8 PF06259.7 AIF85097.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Peptidase_S9 PF00326.16 AIF85097.1 - 0.04 13.1 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 AIF85097.1 - 0.042 12.1 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RNR_N PF08343.5 AIF85097.1 - 0.078 12.7 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Lipase_3 PF01764.20 AIF85097.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FeoC PF09012.5 AIF85100.1 - 0.0022 17.6 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_Tnp_ISL3 PF13542.1 AIF85100.1 - 0.13 11.4 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.2 AIF85100.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 MarR family DUF3764 PF12594.3 AIF85102.1 - 0.0071 16.0 0.2 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3764) ABM PF03992.11 AIF85102.1 - 0.023 14.7 0.1 0.061 13.3 0.0 1.8 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase GSDH PF07995.6 AIF85102.1 - 0.048 12.7 0.0 0.053 12.5 0.0 1.0 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Cytochrom_B562 PF07361.6 AIF85102.1 - 0.1 12.9 0.5 0.17 12.2 0.3 1.3 1 0 0 1 1 1 0 Cytochrome b562 BNR_2 PF13088.1 AIF85103.1 - 4.6e-05 22.8 0.1 0.00023 20.5 0.0 2.0 1 1 0 2 2 2 1 BNR repeat-like domain BNR PF02012.15 AIF85103.1 - 0.47 10.4 11.8 0.23 11.4 0.8 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat Polysacc_deac_1 PF01522.16 AIF85104.1 - 1.7e-11 43.7 0.0 6.7e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Big_3_4 PF13754.1 AIF85104.1 - 0.003 17.8 1.3 0.003 17.8 0.9 3.3 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 3) TerC PF03741.11 AIF85105.1 - 1.9e-50 170.8 15.3 1.9e-50 170.8 10.6 1.5 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF3397 PF11877.3 AIF85105.1 - 5.5 7.0 17.5 0.21 11.5 2.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3397) zf-C2H2_4 PF13894.1 AIF85106.1 - 1.7e-05 24.7 0.7 2.3e-05 24.4 0.5 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 AIF85106.1 - 6.6e-05 22.9 0.2 7.9e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 AIF85106.1 - 0.0011 19.0 0.1 0.0011 19.0 0.0 1.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AIF85106.1 - 0.0058 16.9 1.5 0.0075 16.5 1.0 1.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF629 PF04780.7 AIF85106.1 - 0.055 11.9 0.0 0.055 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-CHCC PF10276.4 AIF85106.1 - 0.082 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger domain zf-H2C2_2 PF13465.1 AIF85106.1 - 0.84 10.0 3.1 2.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain HicB PF05534.7 AIF85107.1 - 0.003 17.0 0.0 0.0065 16.0 0.0 1.6 2 0 0 2 2 2 1 HicB family RNR_N PF08343.5 AIF85107.1 - 0.033 13.9 0.1 0.077 12.8 0.1 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal DUF2555 PF10742.4 AIF85107.1 - 0.036 13.7 0.1 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) MarR_2 PF12802.2 AIF85108.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 MarR family SSF PF00474.12 AIF85108.1 - 0.15 10.6 3.0 0.21 10.1 2.1 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family MgtC PF02308.11 AIF85109.1 - 9.9e-28 96.6 6.3 1.2e-27 96.4 4.4 1.0 1 0 0 1 1 1 1 MgtC family Chromate_transp PF02417.10 AIF85109.1 - 0.056 13.0 4.8 0.072 12.6 3.3 1.2 1 0 0 1 1 1 0 Chromate transporter EI24 PF07264.6 AIF85109.1 - 0.059 12.7 0.9 0.1 12.0 0.6 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) AA_permease_C PF13906.1 AIF85109.1 - 0.8 9.6 3.2 1 9.2 0.4 2.4 3 0 0 3 3 3 0 C-terminus of AA_permease DUF2721 PF11026.3 AIF85109.1 - 1.7 8.3 5.8 1.4 8.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF308 PF03729.8 AIF85111.1 - 1.1e-09 38.1 50.0 2.6e-05 24.1 14.1 3.2 2 1 1 3 3 3 3 Short repeat of unknown function (DUF308) Tetraspannin PF00335.15 AIF85114.1 - 0.13 11.5 2.9 0.18 11.0 2.0 1.2 1 0 0 1 1 1 0 Tetraspanin family SnoaL PF07366.7 AIF85115.1 - 5.4e-08 32.4 0.0 5.8e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AIF85115.1 - 0.055 13.8 0.0 0.065 13.6 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain GPDPase_memb PF10110.4 AIF85117.1 - 0.0098 15.3 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Collagen PF01391.13 AIF85118.1 - 0.055 13.0 1.2 0.055 13.0 0.9 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF2312 PF10073.4 AIF85120.1 - 0.13 11.6 0.4 18 4.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Kin17_mid PF10357.4 AIF85121.1 - 0.0089 15.6 0.1 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein PSD2 PF07624.6 AIF85121.1 - 0.041 13.5 0.2 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) YqbF PF14553.1 AIF85124.1 - 0.39 10.4 2.0 0.43 10.2 1.4 1.2 1 0 0 1 1 1 0 YqbF, hypothetical protein domain FMN_red PF03358.10 AIF85125.1 - 1.1e-41 141.8 0.0 1.5e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AIF85125.1 - 9.2e-09 35.0 0.0 1.4e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin-like fold DUF608 PF04685.8 AIF85126.1 - 2.3e-07 29.8 0.1 3.5e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 AIF85126.1 - 4.2e-05 22.4 0.1 0.14 10.8 0.0 2.3 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase GlcNAc_2-epim PF07221.6 AIF85126.1 - 0.026 13.5 0.0 0.067 12.1 0.0 1.6 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Trehalase PF01204.13 AIF85126.1 - 0.13 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Trehalase Dodecin PF07311.7 AIF85127.1 - 7.4e-24 83.5 0.8 8.1e-24 83.4 0.6 1.0 1 0 0 1 1 1 1 Dodecin Glycos_transf_1 PF00534.15 AIF85128.1 - 2.8e-22 78.9 0.0 5.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AIF85128.1 - 2.6e-08 34.0 0.1 6.9e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AIF85128.1 - 0.00028 21.0 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 MacB_PCD PF12704.2 AIF85129.1 - 0.037 13.6 0.1 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 MacB-like periplasmic core domain DUF4179 PF13786.1 AIF85129.1 - 0.077 13.2 0.1 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Herpes_US9 PF06072.6 AIF85129.1 - 0.34 10.7 4.3 0.63 9.9 3.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Glyco_tranf_2_3 PF13641.1 AIF85131.1 - 9.6e-10 38.6 0.0 2e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AIF85131.1 - 9.5e-09 35.2 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Fringe PF02434.11 AIF85131.1 - 4.8e-05 22.6 0.0 7.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fringe-like EF-hand_10 PF14788.1 AIF85132.1 - 0.12 12.0 0.7 1.6 8.4 0.1 2.6 2 1 0 2 2 2 0 EF hand DNA_alkylation PF08713.6 AIF85133.1 - 5e-65 218.9 0.1 5.7e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF167 PF02594.11 AIF85134.1 - 5.8e-16 58.1 0.1 6.3e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Tautomerase_2 PF14552.1 AIF85134.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 Tautomerase enzyme Mrr_N PF14338.1 AIF85134.1 - 0.068 13.2 0.1 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Mrr N-terminal domain CAP PF00188.21 AIF85135.1 - 0.00047 20.6 0.1 0.0013 19.1 0.1 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Big_3_4 PF13754.1 AIF85135.1 - 0.0095 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) zinc_ribbon_2 PF13240.1 AIF85135.1 - 0.02 14.3 1.1 0.039 13.4 0.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF85135.1 - 0.11 11.7 2.4 0.24 10.6 1.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ipi1_N PF12333.3 AIF85136.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Nodulin_late PF07127.6 AIF85136.1 - 0.15 12.2 0.8 0.17 12.0 0.6 1.2 1 0 0 1 1 1 0 Late nodulin protein Peptidase_M3 PF01432.15 AIF85137.1 - 7.5e-46 157.1 0.0 1.1e-45 156.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.5 AIF85137.1 - 2.4e-11 43.4 0.1 4e-10 39.5 0.0 2.8 3 0 0 3 3 3 1 Oligopeptidase F Peptidase_MA_2 PF13485.1 AIF85137.1 - 0.0033 17.4 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase MA superfamily B56 PF01603.15 AIF85137.1 - 0.049 12.2 0.0 0.082 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SBF PF01758.11 AIF85138.1 - 3.8e-15 55.7 15.5 3.8e-15 55.7 10.8 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family UNC-93 PF05978.11 AIF85138.1 - 0.068 12.6 0.2 0.068 12.6 0.1 2.5 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Fumarate_red_D PF02313.12 AIF85138.1 - 1.4 8.8 14.7 2 8.3 0.2 3.3 3 1 1 4 4 4 0 Fumarate reductase subunit D HpcH_HpaI PF03328.9 AIF85139.1 - 6.5e-50 169.0 2.3 8.6e-50 168.6 1.6 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 AIF85139.1 - 5.4e-17 61.6 0.2 5.8e-08 31.9 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 AIF85139.1 - 0.055 12.0 0.2 0.084 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ADH_zinc_N PF00107.21 AIF85140.1 - 4.4e-31 107.1 0.1 8.3e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIF85140.1 - 2e-27 95.0 0.0 4.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIF85140.1 - 1.1e-15 58.6 0.2 2.8e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 AIF85140.1 - 0.051 13.0 0.1 0.081 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase dsDNA_bind PF01984.15 AIF85141.1 - 8.3e-26 90.0 1.0 9.6e-26 89.8 0.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Tom5 PF10642.4 AIF85141.1 - 0.0023 17.5 0.3 0.01 15.4 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial import receptor subunit or translocase Ribosomal_S19e PF01090.14 AIF85142.1 - 1.1e-54 183.6 0.1 1.3e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.5 AIF85142.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain MarR PF01047.17 AIF85142.1 - 0.12 12.1 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 MarR family Rpr2 PF04032.11 AIF85143.1 - 1.9e-16 59.7 0.2 2.3e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_4 PF13717.1 AIF85143.1 - 0.0097 15.5 1.2 0.55 9.9 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain PapD-like PF14874.1 AIF85143.1 - 0.013 15.4 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 Flagellar-associated PapD-like zinc_ribbon_5 PF13719.1 AIF85143.1 - 0.014 15.0 1.2 0.65 9.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF4636 PF15468.1 AIF85143.1 - 0.015 14.7 0.2 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) IBR PF01485.16 AIF85143.1 - 0.037 13.8 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 IBR domain zf-Sec23_Sec24 PF04810.10 AIF85143.1 - 0.064 12.8 0.5 4.6 6.8 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger C1_1 PF00130.17 AIF85143.1 - 0.085 12.6 0.2 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF572 PF04502.8 AIF85143.1 - 0.089 11.9 1.4 0.1 11.7 1.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cys_rich_KTR PF14205.1 AIF85143.1 - 0.098 12.1 0.8 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich KTR Cript PF10235.4 AIF85143.1 - 0.1 12.9 0.8 0.47 10.8 0.6 1.9 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-DNL PF05180.7 AIF85143.1 - 0.52 10.0 2.9 0.51 10.0 0.2 2.0 2 0 0 2 2 2 0 DNL zinc finger EMG1 PF03587.9 AIF85144.1 - 4.9e-43 146.7 0.0 5.6e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UbiA PF01040.13 AIF85145.1 - 3.3e-33 115.0 22.6 4.4e-33 114.5 15.7 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Abhydrolase_2 PF02230.11 AIF85145.1 - 0.05 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SecE PF00584.15 AIF85145.1 - 1 8.9 9.2 1.2 8.8 0.6 3.1 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF1218 PF06749.7 AIF85145.1 - 1.1 9.7 5.0 0.39 11.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) AsnC_trans_reg PF01037.16 AIF85146.1 - 4e-15 55.2 0.1 6.7e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 AIF85146.1 - 8.3e-14 50.7 0.8 2e-13 49.4 0.6 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF85146.1 - 2e-09 36.8 0.0 3.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.17 AIF85146.1 - 1.9e-06 27.4 0.1 5.2e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AIF85146.1 - 8.5e-06 25.3 0.9 1.4e-05 24.6 0.1 1.8 2 0 0 2 2 1 1 Sugar-specific transcriptional regulator TrmB MotA_activ PF09114.5 AIF85146.1 - 6.2e-05 22.6 1.0 0.0001 22.0 0.6 1.5 1 1 0 1 1 1 1 Transcription factor MotA, activation domain B-block_TFIIIC PF04182.7 AIF85146.1 - 8.6e-05 22.3 0.8 0.00013 21.7 0.6 1.4 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_11 PF08279.7 AIF85146.1 - 0.00067 19.2 0.4 0.0015 18.0 0.3 1.6 1 0 0 1 1 1 1 HTH domain HTH_27 PF13463.1 AIF85146.1 - 0.0016 18.7 0.1 0.0063 16.8 0.0 1.9 2 1 1 3 3 3 1 Winged helix DNA-binding domain Ribosomal_S25 PF03297.10 AIF85146.1 - 0.002 18.1 2.5 0.0037 17.2 0.6 1.9 2 0 0 2 2 2 1 S25 ribosomal protein MarR_2 PF12802.2 AIF85146.1 - 0.0027 17.3 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 AIF85146.1 - 0.0042 16.8 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.15 AIF85146.1 - 0.0048 16.9 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_34 PF13601.1 AIF85146.1 - 0.0079 16.2 0.2 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.15 AIF85146.1 - 0.01 15.5 0.2 0.021 14.4 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Sulfolobus_pRN PF05584.6 AIF85146.1 - 0.015 15.2 0.2 0.043 13.7 0.1 1.7 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein HTH_45 PF14947.1 AIF85146.1 - 0.025 14.3 0.4 0.069 12.9 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix Linocin_M18 PF04454.7 AIF85146.1 - 0.038 12.9 0.2 0.05 12.4 0.1 1.1 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Mga PF05043.8 AIF85146.1 - 0.04 14.1 0.1 0.092 13.0 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain FeoC PF09012.5 AIF85146.1 - 0.044 13.4 0.2 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator Fe_dep_repress PF01325.14 AIF85146.1 - 0.12 12.3 0.2 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Semialdhyde_dhC PF02774.13 AIF85147.1 - 5.1e-38 130.7 0.0 7.6e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 AIF85147.1 - 1.6e-26 92.9 0.0 3.4e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 AIF85147.1 - 5e-05 22.8 0.1 0.02 14.3 0.0 2.6 3 0 0 3 3 3 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.15 AIF85147.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 AIF85147.1 - 0.056 12.6 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Ldh_1_N PF00056.18 AIF85147.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AIF85147.1 - 0.064 13.2 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding GFO_IDH_MocA PF01408.17 AIF85147.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Aminotran_1_2 PF00155.16 AIF85148.1 - 2.2e-44 151.8 0.0 2.9e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CbiA PF01656.18 AIF85149.1 - 8.5e-29 100.3 0.0 1e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 AIF85149.1 - 1.6e-17 63.8 0.0 3.5e-17 62.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AIF85149.1 - 5e-06 26.2 0.0 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AIF85149.1 - 0.00083 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 AIF85149.1 - 0.025 14.1 0.2 0.063 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AIF85149.1 - 0.039 14.7 0.0 0.37 11.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AIF85149.1 - 0.042 14.1 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 AIF85149.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain CobD_Cbib PF03186.8 AIF85150.1 - 9.9e-93 310.4 4.0 1.2e-92 310.0 2.8 1.0 1 0 0 1 1 1 1 CobD/Cbib protein CobS PF02654.10 AIF85151.1 - 4.7e-47 160.5 15.8 5.3e-47 160.3 10.9 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase NTP_transf_3 PF12804.2 AIF85152.1 - 2.7e-10 40.5 0.2 3e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AIF85152.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ribosomal_S27e PF01667.12 AIF85153.1 - 5.1e-16 57.9 1.4 5.6e-16 57.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 AIF85153.1 - 2.1e-05 23.7 0.2 3e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding DZR PF12773.2 AIF85153.1 - 0.0011 18.6 0.5 0.0014 18.4 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 AIF85153.1 - 0.0012 18.4 0.7 0.0015 18.1 0.5 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 AIF85153.1 - 0.015 15.2 1.3 0.023 14.6 0.9 1.3 1 0 0 1 1 1 0 Zinc ribbon domain DUF4206 PF13901.1 AIF85153.1 - 0.017 14.6 0.3 0.019 14.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zinc_ribbon_5 PF13719.1 AIF85153.1 - 0.036 13.6 3.9 1.4 8.5 2.9 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AIF85153.1 - 0.038 13.6 4.2 1.8 8.3 3.1 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF85153.1 - 0.046 12.9 2.7 0.23 10.7 1.9 1.9 1 1 1 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AIF85153.1 - 0.048 13.4 0.8 0.057 13.2 0.5 1.1 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_6 PF14599.1 AIF85153.1 - 0.063 13.0 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 Zinc-ribbon Lar_restr_allev PF14354.1 AIF85153.1 - 0.068 13.4 1.7 0.26 11.6 1.2 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar HypA PF01155.14 AIF85153.1 - 0.11 12.1 0.4 0.13 11.9 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 AIF85153.1 - 0.13 12.0 0.7 6.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_RNApol_7kD PF03604.8 AIF85153.1 - 0.14 11.6 5.7 0.46 10.0 0.2 2.1 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS91 PF14319.1 AIF85153.1 - 0.15 11.5 0.6 0.18 11.3 0.4 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain Stc1 PF12898.2 AIF85153.1 - 0.18 11.9 1.7 0.22 11.6 1.2 1.3 1 1 0 1 1 1 0 Stc1 domain Yippee-Mis18 PF03226.9 AIF85153.1 - 0.25 11.4 2.3 1.4 9.0 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TFIIS_C PF01096.13 AIF85153.1 - 0.28 10.8 3.4 4.9 6.8 2.3 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.1 AIF85153.1 - 0.35 10.4 4.1 1.1 8.7 0.1 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 AIF85153.1 - 0.36 9.9 1.7 3.3 6.8 1.2 2.0 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-C2H2_3 PF13878.1 AIF85153.1 - 0.48 10.0 2.3 11 5.6 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Elf1 PF05129.8 AIF85153.1 - 0.6 9.8 2.7 2 8.1 1.8 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-LSD1 PF06943.7 AIF85153.1 - 0.64 9.6 2.7 1.9 8.1 0.2 2.1 2 0 0 2 2 2 0 LSD1 zinc finger zf-C2HC_2 PF13913.1 AIF85153.1 - 3.6 7.3 6.0 10 5.9 0.8 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CCHC_6 PF15288.1 AIF85153.1 - 8 6.2 6.2 2.1 8.0 1.1 2.3 2 1 1 3 3 3 0 Zinc knuckle Ribosomal_L44 PF00935.14 AIF85154.1 - 9.2e-25 86.4 10.7 9.2e-25 86.4 7.4 1.4 2 0 0 2 2 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 AIF85154.1 - 0.00025 20.7 3.7 0.0015 18.3 0.1 2.2 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L33 PF00471.15 AIF85154.1 - 0.011 16.0 9.4 0.012 15.8 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein L33 Elf1 PF05129.8 AIF85154.1 - 0.045 13.4 3.2 1.7 8.4 0.4 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-ISL3 PF14690.1 AIF85154.1 - 0.056 13.4 4.7 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-FPG_IleRS PF06827.9 AIF85154.1 - 0.074 12.7 2.4 0.77 9.4 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Nudix_N_2 PF14803.1 AIF85154.1 - 0.076 12.7 2.7 4.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal Rpr2 PF04032.11 AIF85154.1 - 0.088 12.6 5.1 0.14 12.0 3.5 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.9 AIF85154.1 - 0.095 12.6 5.2 0.61 10.0 0.2 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_4 PF07975.7 AIF85154.1 - 0.13 12.3 2.9 0.43 10.6 0.2 2.1 2 0 0 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 AIF85154.1 - 0.14 12.1 1.7 5.2 7.1 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L37ae PF01780.14 AIF85154.1 - 0.23 11.3 8.0 2.1 8.2 1.5 2.2 1 1 1 2 2 2 0 Ribosomal L37ae protein family DZR PF12773.2 AIF85154.1 - 0.25 11.1 5.9 1.2 9.0 4.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 AIF85154.1 - 0.32 10.8 2.6 7.9 6.3 0.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-DNL PF05180.7 AIF85154.1 - 0.39 10.4 4.2 0.77 9.5 0.6 2.2 2 0 0 2 2 2 0 DNL zinc finger zf-Dof PF02701.10 AIF85154.1 - 0.74 9.7 4.8 1.9 8.4 0.2 2.3 2 1 0 2 2 2 0 Dof domain, zinc finger TFIIS_C PF01096.13 AIF85154.1 - 1 9.0 6.2 6 6.5 1.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1 PF03811.8 AIF85154.1 - 1.1 8.7 5.8 5.2 6.6 0.2 2.9 2 1 1 3 3 3 0 InsA N-terminal domain zf-AN1 PF01428.11 AIF85154.1 - 1.5 8.7 5.0 1.1 9.2 0.6 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger zf-HIT PF04438.11 AIF85154.1 - 4.6 6.9 8.3 9.2 6.0 1.1 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_6 PF13912.1 AIF85155.1 - 0.00016 21.4 3.3 0.038 13.9 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AIF85155.1 - 0.0009 19.4 12.0 0.011 15.9 1.7 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type XPA_N PF01286.13 AIF85155.1 - 0.0029 17.2 4.3 0.53 10.0 0.3 2.2 2 0 0 2 2 2 2 XPA protein N-terminal zinc_ribbon_4 PF13717.1 AIF85155.1 - 0.0036 16.9 1.7 0.87 9.3 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AIF85155.1 - 0.0044 16.5 2.0 0.91 9.1 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-DNA_Pol PF08996.5 AIF85155.1 - 0.01 15.2 0.5 0.011 15.1 0.4 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DZR PF12773.2 AIF85155.1 - 0.032 14.0 0.3 0.051 13.4 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Mut7-C PF01927.11 AIF85155.1 - 0.039 13.9 0.6 0.05 13.5 0.4 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-C2H2_4 PF13894.1 AIF85155.1 - 0.052 13.8 15.4 0.41 11.1 0.3 3.0 2 1 1 3 3 3 0 C2H2-type zinc finger zf-trcl PF13451.1 AIF85155.1 - 0.11 12.1 2.5 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain Lar_restr_allev PF14354.1 AIF85155.1 - 0.11 12.7 1.0 0.86 9.9 0.7 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.8 AIF85155.1 - 0.21 11.0 1.6 4.3 6.8 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FUR PF01475.14 AIF85155.1 - 0.22 11.4 8.8 0.26 11.2 6.1 1.3 1 1 0 1 1 1 0 Ferric uptake regulator family c-SKI_SMAD_bind PF08782.5 AIF85155.1 - 0.26 11.4 7.2 1.1 9.4 0.5 2.1 1 1 1 2 2 2 0 c-SKI Smad4 binding domain FYVE PF01363.16 AIF85155.1 - 2.6 8.0 10.4 6.6 6.7 7.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.5 AIF85155.1 - 2.7 8.0 6.2 17 5.4 0.4 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-LYAR PF08790.6 AIF85155.1 - 3 7.6 11.1 8.1 6.2 0.3 2.6 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_6 PF14599.1 AIF85155.1 - 4.3 7.2 6.4 3 7.7 0.5 2.2 1 1 1 2 2 2 0 Zinc-ribbon YhfH PF14149.1 AIF85155.1 - 4.3 7.2 6.0 6.3 6.6 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein 4HBT PF03061.17 AIF85156.1 - 0.021 14.9 0.0 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 Thioesterase superfamily Myosin_N PF02736.14 AIF85156.1 - 0.13 11.9 0.6 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Cpn60_TCP1 PF00118.19 AIF85157.1 - 1.6e-171 571.2 13.9 1.8e-171 571.0 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ustilago_mating PF05722.7 AIF85157.1 - 0.04 13.2 0.2 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Ustilago B locus mating-type protein PfkB PF00294.19 AIF85158.1 - 5.3e-17 61.8 0.5 7e-17 61.5 0.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pyr_redox PF00070.22 AIF85158.1 - 0.011 16.1 0.1 0.5 10.8 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Copper-bind PF00127.15 AIF85162.1 - 1.8e-09 37.7 1.4 4.1e-09 36.5 0.6 2.0 1 1 1 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF85162.1 - 0.007 16.2 1.1 0.019 14.8 0.1 2.0 2 1 0 2 2 2 1 Cupredoxin-like domain Thiolase_N PF00108.18 AIF85162.1 - 0.011 14.6 2.0 0.013 14.5 0.1 2.0 2 1 1 3 3 3 0 Thiolase, N-terminal domain DLH PF01738.13 AIF85163.1 - 2.9e-57 193.4 0.0 3.5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AIF85163.1 - 2.8e-15 56.3 1.3 3.1e-15 56.1 0.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AIF85163.1 - 4.4e-12 45.6 0.2 2.6e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 AIF85163.1 - 8.1e-10 38.7 1.1 0.0043 16.7 0.0 3.3 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 AIF85163.1 - 7.3e-07 29.2 0.1 0.018 14.9 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 AIF85163.1 - 8.3e-07 28.1 0.0 1.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 AIF85163.1 - 1e-05 24.5 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.7 AIF85163.1 - 0.0018 16.8 0.1 0.037 12.5 0.1 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 AIF85163.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase NAD_binding_2 PF03446.10 AIF85163.1 - 0.016 15.0 0.2 0.077 12.8 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_3 PF07859.8 AIF85163.1 - 0.02 14.4 1.2 1.2 8.6 0.0 2.7 2 2 0 3 3 3 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 AIF85163.1 - 0.026 12.8 0.0 0.41 8.8 0.0 2.0 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF3185 PF11381.3 AIF85163.1 - 0.13 12.0 1.1 3.5 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) BPD_transp_1 PF00528.17 AIF85164.1 - 1.6e-14 53.8 17.8 1.6e-14 53.8 12.3 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.22 AIF85165.1 - 1.1e-30 106.7 0.0 2.2e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AIF85165.1 - 2.8e-10 40.6 0.1 7.2e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AIF85165.1 - 8.7e-06 25.0 0.0 0.0038 16.3 0.1 2.2 1 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 AIF85165.1 - 1.7e-05 23.6 0.1 0.0041 15.7 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 AIF85165.1 - 3.8e-05 22.9 0.0 5.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 AIF85165.1 - 4.8e-05 22.6 0.6 0.083 12.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AIF85165.1 - 6.9e-05 22.9 0.3 0.00016 21.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 AIF85165.1 - 0.00075 18.3 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 AIF85165.1 - 0.0009 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 AIF85165.1 - 0.00095 18.6 0.0 0.0032 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AIF85165.1 - 0.001 19.2 0.5 0.015 15.4 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AIF85165.1 - 0.0036 17.4 0.1 0.029 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AIF85165.1 - 0.0041 17.9 0.6 0.0087 16.8 0.4 2.0 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AIF85165.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 AIF85165.1 - 0.02 14.7 0.4 0.11 12.3 0.3 2.5 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 AIF85165.1 - 0.028 14.3 0.2 0.15 12.0 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 AIF85165.1 - 0.029 14.6 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 AIF85165.1 - 0.029 13.2 0.0 0.063 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 AIF85165.1 - 0.03 14.2 0.2 0.098 12.6 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AIF85165.1 - 0.03 13.7 0.2 0.095 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 AIF85165.1 - 0.036 13.8 0.1 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 AIF85165.1 - 0.045 14.2 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 AIF85165.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AIF85165.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AIF85165.1 - 0.068 13.1 0.2 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 AIF85165.1 - 0.1 12.2 0.1 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AIF85165.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 AIF85165.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NMT1_2 PF13379.1 AIF85166.1 - 1.2e-29 103.4 0.1 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.6 AIF85166.1 - 8.7e-16 58.1 0.1 1.3e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 AIF85166.1 - 4.1e-11 42.7 0.0 1.4e-10 41.0 0.0 1.8 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 AIF85166.1 - 3.2e-06 26.5 0.0 0.0026 17.0 0.0 2.4 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 DUF4179 PF13786.1 AIF85166.1 - 0.14 12.3 0.6 0.45 10.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) ComA PF02679.10 AIF85167.1 - 2.2e-49 167.7 0.4 4.3e-49 166.7 0.1 1.5 2 0 0 2 2 2 1 (2R)-phospho-3-sulfolactate synthase (ComA) TrmB PF01978.14 AIF85167.1 - 0.00029 20.4 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.1 AIF85167.1 - 0.00047 20.2 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 AIF85167.1 - 0.00073 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_43 PF09904.4 AIF85167.1 - 0.0034 17.1 0.1 0.017 14.9 0.0 2.1 3 0 0 3 3 3 1 Winged helix-turn helix HTH_11 PF08279.7 AIF85167.1 - 0.016 14.8 0.1 0.056 13.1 0.0 1.9 2 0 0 2 2 2 0 HTH domain RNA_pol_Rpc34 PF05158.7 AIF85167.1 - 0.084 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF2296 PF10058.4 AIF85168.1 - 0.0018 18.0 1.7 0.0025 17.5 1.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF1272 PF06906.6 AIF85168.1 - 0.0087 15.8 4.0 0.012 15.4 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) DNA_ligase_ZBD PF03119.11 AIF85168.1 - 0.037 13.7 0.3 0.081 12.6 0.2 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain FYVE PF01363.16 AIF85169.1 - 0.00016 21.4 10.0 0.0007 19.4 2.3 2.1 1 1 1 2 2 2 2 FYVE zinc finger zf-HIT PF04438.11 AIF85169.1 - 0.002 17.7 1.8 0.002 17.7 1.2 2.1 2 0 0 2 2 2 1 HIT zinc finger zinc-ribbons_6 PF07191.7 AIF85169.1 - 0.0062 16.3 2.2 0.0077 16.0 1.5 1.2 1 0 0 1 1 1 1 zinc-ribbons RecR PF02132.10 AIF85169.1 - 0.0077 15.6 6.7 0.31 10.5 0.2 2.2 2 0 0 2 2 2 2 RecR protein ZZ PF00569.12 AIF85169.1 - 0.18 11.3 7.9 0.25 10.9 1.9 2.2 1 1 1 2 2 2 0 Zinc finger, ZZ type CpXC PF14353.1 AIF85169.1 - 0.3 11.0 5.3 0.58 10.1 0.7 2.0 1 1 1 2 2 2 0 CpXC protein Zn_ribbon_recom PF13408.1 AIF85169.1 - 0.33 11.2 2.7 0.51 10.6 1.8 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DZR PF12773.2 AIF85169.1 - 0.35 10.7 7.4 0.78 9.6 5.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 AIF85169.1 - 0.63 9.7 5.1 1.5 8.5 3.5 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 AIF85169.1 - 0.75 9.0 8.2 1.2 8.4 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 AIF85169.1 - 1.4 8.6 6.4 4 7.1 4.4 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like RNA_POL_M_15KD PF02150.11 AIF85169.1 - 1.9 8.2 5.6 10 5.8 0.1 2.9 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DUF2256 PF10013.4 AIF85169.1 - 2.1 8.1 8.8 4.6 7.0 2.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Rubredoxin PF00301.15 AIF85169.1 - 3.2 7.6 7.4 26 4.7 0.3 2.3 1 1 1 2 2 2 0 Rubredoxin DUF3279 PF11682.3 AIF85169.1 - 4.7 6.7 9.2 3.3 7.2 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) Zn-ribbon_8 PF09723.5 AIF85169.1 - 5.5 7.0 7.7 39 4.2 0.2 2.6 1 1 1 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AIF85169.1 - 8.8 6.0 7.2 18 5.0 5.0 1.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain AmoC PF04896.7 AIF85171.1 - 5.2e-14 51.8 4.7 6.3e-14 51.6 3.2 1.0 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C DUF2627 PF11118.3 AIF85172.1 - 0.067 13.2 0.6 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DUF3185 PF11381.3 AIF85172.1 - 0.16 11.7 1.9 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) TarH PF02203.10 AIF85172.1 - 0.17 11.7 0.3 0.24 11.2 0.2 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue Na_Pi_cotrans PF02690.10 AIF85172.1 - 0.19 11.4 1.9 0.47 10.1 1.2 1.8 1 1 0 1 1 1 0 Na+/Pi-cotransporter DUF3188 PF11384.3 AIF85172.1 - 3.2 7.4 6.7 1.8 8.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) zf-C2H2 PF00096.21 AIF85173.1 - 0.026 14.8 0.3 0.046 14.0 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF85173.1 - 0.049 13.9 0.4 0.093 13.1 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger SnoaL_2 PF12680.2 AIF85174.1 - 4.2e-08 33.5 0.0 4.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF1250 PF06855.7 AIF85174.1 - 0.023 14.1 0.2 0.055 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) DUF4440 PF14534.1 AIF85174.1 - 0.045 13.9 0.0 0.075 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 AIF85174.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like domain HTH_20 PF12840.2 AIF85175.1 - 1.1e-07 31.5 0.2 6.6e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 AIF85175.1 - 0.0017 17.9 1.2 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 AIF85175.1 - 0.015 15.5 0.3 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_24 PF13412.1 AIF85175.1 - 0.017 14.4 0.7 0.11 11.8 0.1 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PLDc_2 PF13091.1 AIF85175.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain ADH_zinc_N_2 PF13602.1 AIF85176.1 - 1.1e-24 87.7 0.8 3.5e-24 86.1 0.1 2.1 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AIF85176.1 - 1.3e-14 53.8 0.0 2.9e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIF85176.1 - 5.8e-13 48.5 0.0 2e-12 46.8 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain WASH-7_mid PF14744.1 AIF85176.1 - 0.03 13.1 0.1 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 HSP20 PF00011.16 AIF85178.1 - 1.8e-08 34.1 0.7 1.7e-06 27.8 0.5 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 AIF85178.1 - 8.8e-05 22.2 0.4 0.00013 21.6 0.3 1.4 1 1 0 1 1 1 1 GvpH CS PF04969.11 AIF85178.1 - 0.00021 21.7 0.0 0.00034 21.1 0.0 1.3 1 0 0 1 1 1 1 CS domain CTDII PF01556.13 AIF85179.1 - 1.4e-30 105.0 0.8 3.6e-22 78.0 0.1 3.2 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 AIF85179.1 - 3e-29 100.5 3.5 5.1e-29 99.8 2.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AIF85179.1 - 2.8e-13 49.7 14.4 4.6e-13 49.0 10.0 1.4 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 AIF85179.1 - 8.5 5.9 7.5 20 4.8 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain HSP70 PF00012.15 AIF85180.1 - 3.5e-215 715.4 15.7 3e-196 652.9 7.1 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 AIF85180.1 - 3.5e-16 58.6 4.4 1.1e-15 57.1 3.1 1.8 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 AIF85180.1 - 0.00038 20.1 0.1 0.00073 19.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 AIF85180.1 - 0.0023 16.9 0.3 0.0054 15.7 0.2 1.6 1 0 0 1 1 1 1 StbA protein DNA_pack_N PF02500.10 AIF85180.1 - 0.86 9.0 3.5 1.4 8.3 2.5 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Hydantoinase_A PF01968.13 AIF85180.1 - 1.5 7.8 10.0 0.44 9.5 0.3 3.6 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase GrpE PF01025.14 AIF85181.1 - 2.4e-40 137.7 7.1 3.2e-40 137.3 5.0 1.2 1 0 0 1 1 1 1 GrpE DUF3373 PF11853.3 AIF85181.1 - 0.0015 17.2 0.4 0.0015 17.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) DUF1633 PF07794.6 AIF85181.1 - 0.005 14.8 5.0 0.0061 14.5 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) DUF3584 PF12128.3 AIF85181.1 - 0.039 11.2 9.5 0.047 11.0 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Endotoxin_N PF03945.9 AIF85181.1 - 0.088 12.1 1.8 0.13 11.6 1.2 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF1451 PF07295.6 AIF85181.1 - 0.088 12.5 5.7 0.12 12.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) NCKAP5 PF15246.1 AIF85181.1 - 0.2 11.0 4.1 0.26 10.6 2.8 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Spc7 PF08317.6 AIF85181.1 - 0.41 9.2 6.8 0.54 8.8 4.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FadA PF09403.5 AIF85181.1 - 0.59 10.1 12.6 0.88 9.5 8.8 1.4 1 0 0 1 1 1 0 Adhesion protein FadA SspB PF04386.8 AIF85181.1 - 0.65 9.5 0.0 0.65 9.5 0.0 2.3 2 1 0 2 2 1 0 Stringent starvation protein B AAA_13 PF13166.1 AIF85181.1 - 0.88 7.9 6.8 1.1 7.6 4.7 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 AIF85181.1 - 1.1 6.6 3.6 1.5 6.2 2.5 1.0 1 0 0 1 1 1 0 Prominin OmpH PF03938.9 AIF85181.1 - 1.2 9.0 10.9 1.9 8.3 7.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HSP70 PF00012.15 AIF85181.1 - 10 3.9 10.5 14 3.4 7.3 1.1 1 0 0 1 1 1 0 Hsp70 protein Thioredoxin PF00085.15 AIF85182.1 - 1.1e-28 98.9 0.0 1.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AIF85182.1 - 2.8e-09 37.1 0.1 5.6e-08 32.9 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AIF85182.1 - 3.2e-07 30.3 0.0 1.7e-05 24.8 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 AIF85182.1 - 3.2e-05 23.4 0.0 0.00022 20.8 0.0 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 AIF85182.1 - 0.00042 19.8 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 AIF85182.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 AIF85182.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 AIF85182.1 - 0.021 14.6 0.4 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain AhpC-TSA PF00578.16 AIF85182.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family TraF PF13728.1 AIF85182.1 - 0.064 12.7 0.2 0.2 11.1 0.0 1.8 2 1 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 AIF85182.1 - 0.084 12.8 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin TrbC_Ftype PF09673.5 AIF85182.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Ribosomal_L35Ae PF01247.13 AIF85183.1 - 0.07 12.9 0.1 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L35Ae Phage_int_SAM_1 PF02899.12 AIF85184.1 - 0.086 12.9 0.0 41 4.4 0.0 3.0 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Fcf2 PF08698.6 AIF85184.1 - 0.13 12.2 0.7 0.57 10.2 0.2 2.2 2 1 0 2 2 2 0 Fcf2 pre-rRNA processing Desulfoferrod_N PF06397.7 AIF85185.1 - 0.0088 15.4 0.7 0.014 14.7 0.5 1.3 1 0 0 1 1 1 1 Desulfoferrodoxin, N-terminal domain DUF3505 PF12013.3 AIF85185.1 - 0.04 14.1 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) DUF2318 PF10080.4 AIF85185.1 - 0.077 12.7 0.4 0.091 12.5 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-C2H2_2 PF12756.2 AIF85185.1 - 0.096 12.8 0.8 0.13 12.4 0.5 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) eIF-5_eIF-2B PF01873.12 AIF85186.1 - 2.4e-29 101.5 0.0 2.9e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 AIF85186.1 - 2.3e-05 23.6 0.8 4.2e-05 22.7 0.5 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.1 AIF85186.1 - 0.00033 20.8 0.4 0.00054 20.1 0.3 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.7 AIF85186.1 - 0.024 14.7 0.8 0.063 13.3 0.6 1.7 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Cys_rich_KTR PF14205.1 AIF85186.1 - 0.024 14.0 2.1 0.46 9.9 0.1 2.6 2 1 1 3 3 3 0 Cysteine-rich KTR Elf1 PF05129.8 AIF85186.1 - 0.045 13.4 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SUI1 PF01253.17 AIF85186.1 - 0.13 12.1 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor SUI1 DZR PF12773.2 AIF85186.1 - 0.22 11.3 1.1 0.67 9.8 0.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF85186.1 - 0.23 10.6 3.9 2.2 7.6 2.8 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 AIF85186.1 - 0.85 9.4 3.3 3.5 7.4 0.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Glycos_transf_2 PF00535.21 AIF85187.1 - 4.3e-32 111.1 0.3 7.4e-32 110.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIF85187.1 - 2.8e-27 96.0 0.4 1.9e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 AIF85187.1 - 9.8e-19 67.1 1.1 1e-17 63.7 0.7 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 AIF85187.1 - 3.9e-14 52.8 6.2 3.9e-14 52.8 4.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 AIF85187.1 - 1.1e-06 28.1 0.1 0.0001 21.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF85187.1 - 0.00082 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AIF85187.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1936 PF09151.5 AIF85187.1 - 0.025 14.0 0.2 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Imm32 PF15579.1 AIF85187.1 - 0.091 12.3 0.2 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 32 Fringe PF02434.11 AIF85187.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Fringe-like UDPG_MGDP_dh PF00984.14 AIF85188.1 - 5.8e-19 68.1 0.1 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.9 AIF85188.1 - 7.1e-09 35.3 0.0 0.00063 19.1 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 AIF85188.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 AIF85188.1 - 0.00016 21.3 0.1 0.00038 20.1 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 AIF85188.1 - 0.0031 16.6 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPMT PF05724.6 AIF85188.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 AIF85188.1 - 0.036 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 AIF85188.1 - 0.085 12.8 0.3 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Coatomer_b_Cpla PF14806.1 AIF85188.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Antimicrobial20 PF08256.6 AIF85188.1 - 0.67 10.4 2.3 59 4.4 0.8 2.9 2 0 0 2 2 2 0 Aurein-like antibiotic peptide zf-C2H2_2 PF12756.2 AIF85189.1 - 0.014 15.4 0.1 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Glycos_transf_2 PF00535.21 AIF85190.1 - 8.2e-33 113.4 0.2 1.3e-32 112.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AIF85190.1 - 1.1e-30 107.1 0.3 1.1e-29 103.8 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 AIF85190.1 - 2.2e-18 65.9 0.4 5.5e-18 64.6 0.3 1.6 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 AIF85190.1 - 8.2e-15 55.0 6.9 8.2e-15 55.0 4.8 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 AIF85190.1 - 7.1e-08 31.9 0.4 1.4e-05 24.4 0.0 2.6 2 1 1 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AIF85190.1 - 1.2e-06 27.8 0.1 1.9e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AIF85190.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 TraP PF07296.6 AIF85190.1 - 0.082 11.8 2.1 0.61 9.0 0.4 2.2 2 0 0 2 2 2 0 TraP protein Polysacc_deac_1 PF01522.16 AIF85191.1 - 2e-14 53.2 0.0 2.9e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Cas_GSU0054 PF09609.5 AIF85191.1 - 0.041 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) UDPG_MGDP_dh PF00984.14 AIF85192.1 - 1.6e-18 66.7 0.0 2.9e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.9 AIF85192.1 - 1.5e-09 37.4 0.0 0.00012 21.5 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 AIF85192.1 - 0.00013 21.6 0.1 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AIF85192.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AIF85192.1 - 0.00068 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPMT PF05724.6 AIF85192.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 AIF85192.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 AIF85192.1 - 0.039 13.9 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_18 PF12847.2 AIF85192.1 - 0.048 14.2 0.0 0.29 11.7 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain NAD_binding_7 PF13241.1 AIF85192.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DegT_DnrJ_EryC1 PF01041.12 AIF85193.1 - 1.1e-121 406.3 0.6 1.2e-121 406.1 0.4 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AIF85193.1 - 4.1e-08 32.5 0.0 7.8e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AIF85193.1 - 1.8e-05 23.2 0.1 3.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 AIF85193.1 - 4.1e-05 22.8 2.6 8e-05 21.9 1.8 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 AIF85193.1 - 0.00061 18.4 0.0 0.00082 18.0 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain ComK PF06338.6 AIF85193.1 - 0.037 13.4 0.0 0.067 12.6 0.0 1.5 1 1 0 1 1 1 0 ComK protein Ammonium_transp PF00909.16 AIF85194.1 - 3e-111 371.7 29.8 3.4e-111 371.5 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ArsA_ATPase PF02374.10 AIF85195.1 - 4.3e-66 223.0 0.0 5.1e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 AIF85195.1 - 2.6e-11 43.2 0.3 3e-10 39.8 0.0 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AIF85195.1 - 1.4e-05 25.0 0.0 4.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 AIF85195.1 - 0.00044 19.5 0.0 0.00075 18.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family IstB_IS21 PF01695.12 AIF85195.1 - 0.037 13.4 0.2 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 AIF85195.1 - 0.043 13.5 1.3 0.099 12.4 0.9 1.6 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 AIF85195.1 - 0.079 11.7 0.1 0.18 10.5 0.0 1.5 2 0 0 2 2 2 0 ArgK protein Fer4 PF00037.22 AIF85196.1 - 3.9e-09 35.7 12.3 4.6e-06 25.9 1.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AIF85196.1 - 1.8e-08 34.6 29.3 1.8e-05 24.9 7.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF85196.1 - 9.7e-08 31.9 23.3 5.1e-05 23.2 5.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIF85196.1 - 8.6e-07 29.1 7.3 3.5e-06 27.1 5.0 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIF85196.1 - 9.5e-07 28.4 12.8 0.002 17.9 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 AIF85196.1 - 1.3e-06 27.9 11.5 0.0055 16.5 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AIF85196.1 - 2e-06 27.4 19.7 3.8e-05 23.4 6.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AIF85196.1 - 4.4e-06 26.9 9.6 0.00017 21.8 3.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 AIF85196.1 - 1.6e-05 25.1 8.2 9.1e-05 22.8 4.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 AIF85196.1 - 1.9e-05 24.4 7.9 0.00085 19.1 5.5 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIF85196.1 - 3.8e-05 23.6 6.6 0.027 14.7 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AIF85196.1 - 9.1e-05 22.9 7.7 0.094 13.2 1.6 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_16 PF13484.1 AIF85196.1 - 0.00011 22.8 7.3 0.004 17.8 5.8 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_13 PF13370.1 AIF85196.1 - 0.00086 19.6 8.7 0.12 12.7 0.3 2.8 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_11 PF13247.1 AIF85196.1 - 0.0047 16.7 0.7 2 8.3 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 AIF85196.1 - 0.055 14.0 16.2 0.2 12.2 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain NICE-3 PF07406.6 AIF85198.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NICE-3 protein TIG PF01833.19 AIF85200.1 - 5e-05 23.2 0.1 7.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 IPT/TIG domain A2M_N PF01835.14 AIF85200.1 - 0.00015 21.9 0.1 0.00025 21.2 0.1 1.6 1 1 0 1 1 1 1 MG2 domain Qn_am_d_aIII PF09099.5 AIF85200.1 - 0.00099 19.3 0.0 0.0028 17.9 0.0 1.7 1 1 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain III CarboxypepD_reg PF13620.1 AIF85200.1 - 0.0018 18.2 0.5 0.0035 17.3 0.4 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain BiPBP_C PF06832.7 AIF85200.1 - 0.0079 16.0 0.2 0.026 14.4 0.1 1.9 1 1 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family Big_3_4 PF13754.1 AIF85200.1 - 0.016 15.5 1.7 0.016 15.5 1.2 2.5 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF4625 PF15418.1 AIF85200.1 - 0.027 14.5 1.0 0.13 12.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4625) FliD_N PF02465.13 AIF85200.1 - 0.14 12.5 3.2 2.1 8.7 2.3 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus NPCBM_assoc PF10633.4 AIF85200.1 - 0.14 12.2 1.8 0.5 10.4 0.1 2.6 2 1 1 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase BNR_2 PF13088.1 AIF85202.1 - 1.7e-09 37.3 0.0 1.7e-06 27.5 0.0 3.3 2 1 1 3 3 3 2 BNR repeat-like domain BNR PF02012.15 AIF85202.1 - 0.21 11.5 12.6 2.7 8.1 0.0 6.3 7 0 0 7 7 7 0 BNR/Asp-box repeat DUF1697 PF08002.6 AIF85203.1 - 1.7e-39 134.9 0.0 2.1e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) 3-dmu-9_3-mt PF06983.8 AIF85204.1 - 4.8e-70 233.2 0.4 2.8e-44 150.1 0.1 2.0 2 0 0 2 2 2 2 3-demethylubiquinone-9 3-methyltransferase Glyoxalase_2 PF12681.2 AIF85204.1 - 1.1e-05 25.9 0.0 8.6e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 AIF85204.1 - 1.4e-05 25.1 0.0 0.00057 19.8 0.0 2.7 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tetraspannin PF00335.15 AIF85205.1 - 0.0037 16.5 0.1 0.0056 15.9 0.1 1.3 1 0 0 1 1 1 1 Tetraspanin family VKOR PF07884.9 AIF85205.1 - 0.042 13.6 3.3 0.091 12.6 1.0 1.9 2 0 0 2 2 2 0 Vitamin K epoxide reductase family DUF2593 PF10767.4 AIF85205.1 - 0.068 12.8 0.9 0.13 11.9 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) OppC_N PF12911.2 AIF85205.1 - 3.4 7.1 5.7 0.48 9.8 0.3 2.2 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Pyridox_oxidase PF01243.15 AIF85207.1 - 1.5e-12 47.3 0.0 2.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AIF85207.1 - 1.3e-11 44.5 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HypD PF01924.11 AIF85208.1 - 0.048 12.4 1.1 0.06 12.0 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family Bactofilin PF04519.8 AIF85211.1 - 0.011 15.6 0.4 0.47 10.5 0.0 2.3 2 1 0 2 2 2 0 Polymer-forming cytoskeletal zf-C2H2_4 PF13894.1 AIF85213.1 - 0.0035 17.5 0.3 0.0058 16.8 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger YtkA PF13115.1 AIF85214.1 - 0.0073 16.6 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 1 YtkA-like Big_1 PF02369.11 AIF85214.1 - 0.07 13.0 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) YtkA PF13115.1 AIF85215.1 - 0.017 15.4 0.0 8.6 6.8 0.0 2.2 2 0 0 2 2 2 0 YtkA-like CBS PF00571.23 AIF85216.1 - 1.3e-38 130.4 8.1 6.9e-11 41.7 0.2 4.3 4 0 0 4 4 4 4 CBS domain Ribosomal_S30AE PF02482.14 AIF85216.1 - 0.00012 22.4 1.8 0.00032 21.0 1.3 1.7 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein GSDH PF07995.6 AIF85217.1 - 5.5e-92 308.3 0.0 8.4e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.6 AIF85217.1 - 0.019 14.9 0.0 13 6.2 0.0 3.7 3 0 0 3 3 3 0 Two component regulator propeller adh_short PF00106.20 AIF85219.1 - 5.2e-29 101.3 1.0 7.3e-29 100.8 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AIF85219.1 - 6.6e-21 75.1 0.1 9.2e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AIF85219.1 - 1.6e-11 44.1 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 AIF85219.1 - 2e-07 30.4 0.0 2.8e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 AIF85219.1 - 0.0002 21.0 0.2 0.0009 18.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 AIF85219.1 - 0.0051 16.1 0.3 0.15 11.2 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Patatin PF01734.17 AIF85219.1 - 0.048 13.5 0.1 0.074 12.9 0.1 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase HHH_5 PF14520.1 AIF85219.1 - 0.073 13.2 0.2 0.52 10.5 0.1 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain MFS_1 PF07690.11 AIF85220.1 - 1.6e-48 165.1 71.6 3.4e-44 151.0 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AIF85220.1 - 3e-13 49.1 7.4 3e-13 49.1 5.2 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Cupredoxin_1 PF13473.1 AIF85221.1 - 1.8e-09 37.4 0.1 3.2e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 AIF85221.1 - 3.9e-08 33.4 0.0 6.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family HMG-CoA_red PF00368.13 AIF85223.1 - 1.9e-87 293.3 12.6 2.3e-87 293.0 8.7 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF3759 PF12585.3 AIF85223.1 - 0.16 11.8 2.8 0.78 9.6 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3759) HisG PF01634.13 AIF85224.1 - 5.6e-37 126.8 0.1 7.5e-37 126.4 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 AIF85224.1 - 1.4e-15 57.0 0.0 3e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain Histidinol_dh PF00815.15 AIF85225.1 - 1.1e-135 452.4 7.5 1.4e-135 452.1 5.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Aminotran_1_2 PF00155.16 AIF85226.1 - 1.8e-45 155.4 0.0 2.1e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 AIF85226.1 - 1.2e-08 33.9 0.0 2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.14 AIF85226.1 - 0.00037 19.3 0.0 0.0013 17.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V PC_rep PF01851.17 AIF85226.1 - 0.0069 16.5 0.0 0.027 14.7 0.0 2.1 1 0 0 1 1 1 1 Proteasome/cyclosome repeat DUF1919 PF08942.5 AIF85226.1 - 0.063 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) DDA1 PF10172.4 AIF85226.1 - 0.066 13.0 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase HAD_2 PF13419.1 AIF85227.1 - 1.1e-05 25.7 0.2 0.037 14.2 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AIF85227.1 - 3.3e-05 24.4 0.2 0.00024 21.5 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AIF85227.1 - 0.0006 19.4 0.2 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 AIF85227.1 - 0.0021 18.2 0.1 0.0037 17.4 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 AIF85227.1 - 0.064 12.7 0.2 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase OrfB_Zn_ribbon PF07282.6 AIF85228.1 - 2.6e-23 81.4 1.7 4.4e-23 80.7 1.2 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.14 AIF85228.1 - 3.4e-11 42.9 0.3 8.7e-11 41.6 0.2 1.7 1 1 0 1 1 1 1 Probable transposase Rep_fac-A_C PF08646.5 AIF85228.1 - 0.044 13.4 1.0 0.07 12.8 0.7 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Ribosomal_L37ae PF01780.14 AIF85228.1 - 0.088 12.6 1.2 0.2 11.5 0.8 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 AIF85228.1 - 0.089 12.6 3.3 0.17 11.7 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain IGPD PF00475.13 AIF85230.1 - 1.2e-45 154.9 1.6 1.8e-45 154.3 1.1 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase GATase PF00117.23 AIF85231.1 - 5.2e-33 114.1 0.0 5.9e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AIF85231.1 - 1.4e-09 37.7 0.0 5.1e-08 32.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 AIF85231.1 - 1.1e-08 34.8 0.0 1.6e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 AIF85231.1 - 6.9e-07 29.0 0.0 0.0024 17.5 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family His_biosynth PF00977.16 AIF85232.1 - 5.9e-68 228.5 5.4 6.6e-68 228.3 3.8 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 AIF85232.1 - 1.1e-09 37.8 4.1 1.4e-05 24.4 0.2 2.4 2 1 0 2 2 2 2 PcrB family Dus PF01207.12 AIF85232.1 - 3e-07 29.5 0.7 4.2e-05 22.5 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 AIF85232.1 - 4.6e-07 29.0 2.0 0.00028 19.9 1.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.13 AIF85232.1 - 0.00057 18.8 3.9 0.0044 15.9 0.3 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.9 AIF85232.1 - 0.0006 18.8 1.6 0.2 10.5 0.1 2.3 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 AIF85232.1 - 0.00062 18.8 0.4 0.91 8.5 0.0 2.5 2 1 0 2 2 2 2 Indole-3-glycerol phosphate synthase ThiG PF05690.9 AIF85232.1 - 0.0011 18.0 4.0 0.0049 15.9 0.2 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Oxidored_FMN PF00724.15 AIF85232.1 - 0.0017 17.4 0.1 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family IMPDH PF00478.20 AIF85232.1 - 0.0029 16.5 6.3 0.19 10.5 0.3 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 AIF85232.1 - 0.015 13.8 1.0 0.1 11.1 0.1 2.2 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Pterin_bind PF00809.17 AIF85232.1 - 0.019 14.3 0.7 0.031 13.6 0.5 1.4 1 1 0 1 1 1 0 Pterin binding enzyme CutC PF03932.9 AIF85232.1 - 0.032 13.4 0.7 3.6 6.7 0.0 2.7 2 1 1 3 3 3 0 CutC family QRPTase_C PF01729.14 AIF85232.1 - 0.034 13.6 1.0 0.4 10.1 0.2 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Endonuc-HincII PF09226.6 AIF85232.1 - 0.04 13.2 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease HincII DUF222 PF02720.12 AIF85232.1 - 0.086 11.9 2.4 0.1 11.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF222) DUF4406 PF14359.1 AIF85232.1 - 0.098 12.7 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) NMO PF03060.10 AIF85232.1 - 0.29 10.2 10.2 0.11 11.6 1.7 2.3 1 1 1 2 2 2 0 Nitronate monooxygenase DUF1471 PF07338.8 AIF85232.1 - 0.38 10.4 2.3 8.6 6.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1471) His_biosynth PF00977.16 AIF85233.1 - 3.3e-86 288.2 1.2 3.9e-86 288.0 0.9 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 AIF85233.1 - 6.8e-08 31.6 0.1 0.0004 19.3 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) PcrB PF01884.12 AIF85233.1 - 5.1e-06 25.9 2.0 4.6e-05 22.7 0.2 2.5 2 1 1 3 3 3 1 PcrB family ThiG PF05690.9 AIF85233.1 - 9.8e-06 24.8 0.9 0.041 12.9 0.2 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 AIF85233.1 - 2.7e-05 23.5 0.5 0.033 13.3 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.12 AIF85233.1 - 0.00027 20.1 0.3 0.45 9.6 0.0 2.4 3 0 0 3 3 3 2 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 AIF85233.1 - 0.0022 17.0 0.1 0.043 12.7 0.1 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Trp_syntA PF00290.15 AIF85233.1 - 0.054 12.0 0.2 0.099 11.1 0.1 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Acylphosphatase PF00708.13 AIF85235.1 - 8.1e-27 93.1 0.1 8.7e-27 93.0 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Orn_Arg_deC_N PF02784.11 AIF85236.1 - 1.2e-38 132.7 0.0 1.5e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 AIF85236.1 - 9.2e-09 35.0 0.1 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AAA PF00004.24 AIF85237.1 - 5.7e-100 330.7 0.2 4.7e-51 172.4 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AIF85237.1 - 5.1e-30 103.2 0.3 1.4e-29 101.8 0.2 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AIF85237.1 - 6.8e-18 65.1 0.0 3.3e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AIF85237.1 - 5.4e-15 55.0 0.0 3.6e-09 36.0 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AIF85237.1 - 4.6e-14 52.8 0.1 4.7e-07 29.9 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AIF85237.1 - 1.6e-13 50.9 0.1 1.4e-05 25.2 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AIF85237.1 - 1.6e-11 45.1 0.0 1.3e-05 25.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 AIF85237.1 - 4.7e-11 42.0 0.2 0.00012 20.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 AIF85237.1 - 6.4e-11 42.2 0.0 1.6e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AIF85237.1 - 7.6e-11 42.0 0.0 0.00051 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AIF85237.1 - 9e-11 41.6 0.9 0.00012 21.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AIF85237.1 - 3.8e-10 39.1 0.0 6.3e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 AIF85237.1 - 1.3e-08 34.4 0.2 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.12 AIF85237.1 - 4.9e-08 32.4 0.1 1.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activat PF00158.21 AIF85237.1 - 5.9e-08 32.3 0.4 0.027 13.9 0.0 3.6 3 1 0 3 3 3 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 AIF85237.1 - 5.7e-07 29.4 0.0 0.0011 18.6 0.0 2.7 2 0 0 2 2 2 2 Bacterial dnaA protein Arch_ATPase PF01637.13 AIF85237.1 - 5.7e-07 29.4 0.0 0.0014 18.3 0.1 3.8 2 2 2 4 4 4 2 Archaeal ATPase KaiC PF06745.8 AIF85237.1 - 7e-07 28.5 0.5 0.1 11.6 0.0 3.7 2 1 1 3 3 3 2 KaiC NACHT PF05729.7 AIF85237.1 - 9.6e-07 28.6 0.1 0.13 11.8 0.0 4.0 4 0 0 4 4 4 2 NACHT domain RNA_helicase PF00910.17 AIF85237.1 - 1.3e-06 28.5 0.0 0.035 14.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 AIF85237.1 - 1.4e-06 27.6 2.2 0.033 13.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AIF85237.1 - 1.6e-06 27.6 5.5 0.59 9.4 0.2 4.1 2 2 1 3 3 3 3 AAA domain AAA_28 PF13521.1 AIF85237.1 - 1.7e-06 28.1 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AIF85237.1 - 4e-06 26.4 4.4 0.0051 16.5 0.1 3.3 3 0 0 3 3 3 2 Part of AAA domain PhoH PF02562.11 AIF85237.1 - 1.1e-05 24.7 0.7 0.11 11.7 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_18 PF13238.1 AIF85237.1 - 2.1e-05 24.8 0.0 0.035 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AIF85237.1 - 2.7e-05 23.8 0.1 0.021 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 AIF85237.1 - 4.3e-05 23.5 0.0 0.097 12.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 AIF85237.1 - 6.9e-05 21.8 0.0 0.043 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 AIF85237.1 - 7e-05 21.8 0.1 0.091 11.6 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 AIF85237.1 - 8.5e-05 22.8 0.0 0.66 10.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.6 AIF85237.1 - 0.00058 19.4 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.11 AIF85237.1 - 0.00064 18.6 0.1 0.22 10.3 0.1 2.8 2 1 0 2 2 2 1 AFG1-like ATPase NTPase_1 PF03266.10 AIF85237.1 - 0.00068 19.3 0.3 4 7.1 0.0 3.6 2 1 1 3 3 3 0 NTPase SKI PF01202.17 AIF85237.1 - 0.00095 19.0 0.2 0.49 10.2 0.0 2.7 3 0 0 3 3 2 1 Shikimate kinase DUF2075 PF09848.4 AIF85237.1 - 0.0011 18.0 0.0 0.32 9.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 AIF85237.1 - 0.0014 17.5 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 AIF85237.1 - 0.0015 18.0 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 AIF85237.1 - 0.0017 17.3 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein UPF0079 PF02367.12 AIF85237.1 - 0.0018 17.9 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 AIF85237.1 - 0.0019 17.8 0.1 1.8 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AIF85237.1 - 0.0053 16.6 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Guanylate_kin PF00625.16 AIF85237.1 - 0.0057 16.1 0.2 4.2 6.7 0.0 3.4 2 1 1 3 3 3 0 Guanylate kinase AAA_11 PF13086.1 AIF85237.1 - 0.019 14.5 0.0 0.94 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 AIF85237.1 - 0.02 14.4 0.1 6.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 AIF85237.1 - 0.023 13.6 0.1 1.8 7.4 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain Viral_helicase1 PF01443.13 AIF85237.1 - 0.029 13.8 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 AIF85237.1 - 0.047 13.2 0.5 7.7 6.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CPT PF07931.7 AIF85237.1 - 0.05 13.2 0.0 5.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 AIF85237.1 - 0.068 12.6 0.4 13 5.1 0.0 3.2 2 2 0 2 2 2 0 AAA-like domain IPT PF01745.11 AIF85237.1 - 0.089 11.9 0.2 10 5.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase DUF258 PF03193.11 AIF85237.1 - 0.1 11.7 0.0 6.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 AIF85237.1 - 0.13 12.5 0.2 17 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 AIF85237.1 - 0.13 11.7 2.4 26 4.2 0.0 3.7 4 1 1 5 5 3 0 DEAD/DEAH box helicase PIF1 PF05970.9 AIF85237.1 - 0.15 10.9 0.0 16 4.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Torsin PF06309.6 AIF85237.1 - 0.24 11.3 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Torsin ECR1_N PF14382.1 AIF85238.1 - 2.5e-05 23.4 0.0 5.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 AIF85238.1 - 5.1e-05 23.1 0.2 0.00063 19.6 0.0 2.7 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 Prok-RING_1 PF14446.1 AIF85238.1 - 0.024 14.3 0.9 0.039 13.6 0.6 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PDT PF00800.13 AIF85239.1 - 7.8e-66 221.0 0.0 1.2e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 AIF85239.1 - 6.6e-08 31.8 0.0 1.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain CPSase_sm_chain PF00988.17 AIF85239.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain EMP24_GP25L PF01105.19 AIF85240.1 - 0.00018 21.2 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4330 PF14221.1 AIF85240.1 - 0.0074 16.1 0.9 0.013 15.3 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4330) A2M_N PF01835.14 AIF85240.1 - 0.0083 16.3 0.1 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 MG2 domain FixH PF05751.6 AIF85240.1 - 0.019 14.8 1.2 0.06 13.1 0.1 2.3 1 1 1 2 2 2 0 FixH PPC PF04151.10 AIF85240.1 - 0.041 14.8 0.3 0.078 13.9 0.2 1.5 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain IMPDH PF00478.20 AIF85241.1 - 1.1e-138 461.9 5.6 1.2e-138 461.7 3.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AIF85241.1 - 5.6e-27 93.2 0.4 1.9e-13 49.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 AIF85241.1 - 1.5e-15 57.2 9.2 2.4e-11 43.3 2.9 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 AIF85241.1 - 3.9e-07 29.2 11.8 3.2e-06 26.2 8.0 2.3 2 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 AIF85241.1 - 1e-06 28.2 3.1 0.00029 20.1 0.0 2.9 2 2 1 3 3 3 2 Histidine biosynthesis protein PEP_mutase PF13714.1 AIF85241.1 - 5.9e-05 22.4 1.0 0.022 13.9 0.1 2.5 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase DHO_dh PF01180.16 AIF85241.1 - 0.00029 19.8 4.1 0.00054 19.0 0.4 2.3 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase Radical_SAM PF04055.16 AIF85241.1 - 0.012 15.8 0.1 0.95 9.6 0.0 2.8 2 1 0 2 2 2 0 Radical SAM superfamily Glu_synthase PF01645.12 AIF85241.1 - 0.027 13.3 3.2 0.05 12.5 2.2 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase IGPS PF00218.16 AIF85241.1 - 0.038 13.0 0.0 6.7 5.6 0.0 2.5 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase ThiG PF05690.9 AIF85241.1 - 0.051 12.6 2.9 0.06 12.4 0.4 2.1 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.12 AIF85241.1 - 0.087 11.6 0.1 0.32 9.7 0.0 1.9 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Pterin_bind PF00809.17 AIF85242.1 - 1.6e-40 138.7 0.8 3.4e-39 134.3 0.6 2.2 1 1 0 1 1 1 1 Pterin binding enzyme PEP_mutase PF13714.1 AIF85242.1 - 0.028 13.6 2.4 0.23 10.6 1.7 2.1 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DUF374 PF04028.8 AIF85242.1 - 0.11 11.7 1.5 11 5.3 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF374) ADH_zinc_N PF00107.21 AIF85244.1 - 1.4e-34 118.4 2.7 2.7e-34 117.5 1.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AIF85244.1 - 2.7e-23 81.8 4.2 4.7e-23 81.0 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AIF85244.1 - 1.6e-22 80.7 0.4 3.2e-22 79.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 AIF85244.1 - 0.0068 15.5 1.6 0.016 14.3 1.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Eno-Rase_NADH_b PF12242.3 AIF85244.1 - 0.012 15.3 2.6 0.014 15.1 0.5 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase tRNA-synt_1 PF00133.17 AIF85245.1 - 2.1e-115 386.0 0.0 1.7e-114 383.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AIF85245.1 - 1.8e-32 112.2 0.3 4.5e-32 110.9 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AIF85245.1 - 2.6e-29 102.0 0.1 4.7e-15 55.1 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AIF85245.1 - 8.5e-05 21.9 0.0 0.047 12.9 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 DZR PF12773.2 AIF85245.1 - 0.0044 16.7 0.6 1.6 8.6 0.2 2.5 2 0 0 2 2 2 1 Double zinc ribbon tRNA-synt_1f PF01921.13 AIF85245.1 - 0.0048 15.6 0.0 0.95 8.0 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (K) zf-ribbon_3 PF13248.1 AIF85245.1 - 0.0078 15.3 6.2 0.77 9.0 1.2 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AIF85245.1 - 0.0083 15.5 4.8 0.91 9.1 1.1 2.7 2 1 0 2 2 2 2 zinc-ribbon domain zf-TFIIB PF13453.1 AIF85245.1 - 0.022 13.9 1.3 9.3 5.5 0.0 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.7 AIF85245.1 - 0.028 13.7 0.9 6 6.2 0.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding tRNA-synt_1e PF01406.14 AIF85245.1 - 0.033 13.3 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain UPF0547 PF10571.4 AIF85245.1 - 0.11 12.1 3.6 2.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF531 PF04407.7 AIF85245.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF531) Lar_restr_allev PF14354.1 AIF85245.1 - 0.28 11.5 2.9 4.3 7.7 0.3 3.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 AIF85245.1 - 1.4 8.8 5.5 6 6.9 0.4 3.3 3 0 0 3 3 3 0 Zinc ribbon domain MAF_flag10 PF01973.13 AIF85246.1 - 9e-40 135.9 0.1 1.3e-39 135.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPK_catalytic PF04263.11 AIF85246.1 - 4.5e-06 26.2 1.1 0.00091 18.7 0.2 2.3 1 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain THF_DHG_CYH_C PF02882.14 AIF85246.1 - 0.085 11.9 0.5 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Flavi_NS2B PF01002.14 AIF85247.1 - 0.04 13.5 0.0 0.043 13.3 0.0 1.0 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B DUF1443 PF07280.6 AIF85247.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) DUF945 PF06097.6 AIF85247.1 - 0.11 11.2 3.4 0.11 11.2 2.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) TrbC PF04956.8 AIF85247.1 - 1.3 9.0 6.4 1.4 8.9 4.4 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family Mito_fiss_reg PF05308.6 AIF85248.1 - 0.00012 21.5 2.0 0.00016 21.1 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF2360 PF10152.4 AIF85248.1 - 0.071 13.3 4.1 0.11 12.8 2.8 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) GATase PF00117.23 AIF85249.1 - 4.7e-45 153.3 0.0 7.9e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 AIF85249.1 - 5e-32 109.4 0.1 1.1e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 AIF85249.1 - 1.8e-11 43.4 0.2 3e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 AIF85249.1 - 8.4e-11 41.7 0.0 7.3e-10 38.6 0.0 2.5 2 1 0 2 2 2 1 Peptidase C26 Asn_synthase PF00733.16 AIF85249.1 - 9.1e-08 31.9 0.0 2.4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase ATP_bind_3 PF01171.15 AIF85249.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family QueC PF06508.8 AIF85249.1 - 4.2e-05 22.9 0.0 0.00067 18.9 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 AIF85249.1 - 0.00049 19.6 0.1 0.0051 16.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 AIF85249.1 - 0.0018 16.9 0.0 0.0068 15.0 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase Methyltransf_31 PF13847.1 AIF85250.1 - 2.9e-21 75.6 0.0 4.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF85250.1 - 1.8e-17 63.2 0.0 5.1e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AIF85250.1 - 6.3e-17 61.8 0.0 4.9e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF85250.1 - 1.5e-13 51.2 0.0 2.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF85250.1 - 8.7e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF85250.1 - 2.6e-10 40.2 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF85250.1 - 8.7e-09 35.4 0.0 1.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AIF85250.1 - 6.1e-08 32.0 0.0 8.6e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 AIF85250.1 - 1e-07 31.7 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 AIF85250.1 - 1.2e-07 32.0 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 AIF85250.1 - 3.6e-06 26.1 0.1 8.6e-06 24.9 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase MTS PF05175.9 AIF85250.1 - 1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 AIF85250.1 - 4e-05 23.2 0.0 7.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 AIF85250.1 - 0.00038 20.1 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_20 PF12147.3 AIF85250.1 - 0.0012 17.7 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 AIF85250.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 AIF85250.1 - 0.0038 16.7 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit GidB PF02527.10 AIF85250.1 - 0.0043 16.2 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G RrnaAD PF00398.15 AIF85250.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CheR PF01739.13 AIF85250.1 - 0.057 12.6 0.0 2.8 7.1 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain zf-C2H2 PF00096.21 AIF85251.1 - 7.5e-05 22.8 3.0 0.00014 21.9 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF85251.1 - 0.0014 18.7 1.9 0.0028 17.8 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger Chordopox_A33R PF05966.7 AIF85251.1 - 0.13 11.0 0.2 1.1 7.9 0.0 1.9 1 1 1 2 2 2 0 Chordopoxvirus A33R protein zf-H2C2_2 PF13465.1 AIF85251.1 - 0.39 11.0 7.2 4.9 7.6 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger double domain MEDS PF14417.1 AIF85252.1 - 0.019 14.0 0.1 0.053 12.5 0.1 1.7 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Nitroreductase PF00881.19 AIF85254.1 - 2.2e-25 89.4 0.0 2.7e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family HHH_5 PF14520.1 AIF85257.1 - 0.00019 21.5 0.4 0.00025 21.1 0.3 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 AIF85257.1 - 0.00028 20.2 0.0 0.00037 19.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH PF00633.18 AIF85257.1 - 0.093 12.4 0.1 0.45 10.3 0.0 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix motif TniQ PF06527.6 AIF85257.1 - 0.58 10.3 3.0 9.7 6.3 0.9 2.0 1 1 1 2 2 2 0 TniQ DUF4064 PF13273.1 AIF85258.1 - 0.0061 16.6 0.4 0.0095 16.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF1691 PF07950.6 AIF85258.1 - 0.009 15.9 0.3 0.29 11.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1691) Flavi_NS2B PF01002.14 AIF85258.1 - 0.23 11.0 1.5 1.5 8.3 0.1 2.0 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B Tetraspannin PF00335.15 AIF85258.1 - 2 7.6 7.5 5.2 6.2 4.1 1.9 1 1 1 2 2 2 0 Tetraspanin family RVP PF00077.15 AIF85259.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease Copper-bind PF00127.15 AIF85261.1 - 2.2e-08 34.2 0.3 0.0017 18.5 0.1 2.4 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF85261.1 - 9.7e-05 22.2 1.4 0.055 13.3 0.1 3.1 1 1 1 2 2 2 2 Cupredoxin-like domain RNA_pol_Rpc4 PF05132.9 AIF85261.1 - 0.098 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 MerR-DNA-bind PF09278.6 AIF85263.1 - 0.087 13.2 0.7 1.4 9.4 0.0 2.2 1 1 1 2 2 2 0 MerR, DNA binding CppA_N PF14506.1 AIF85264.1 - 0.012 15.3 0.1 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal Fe_dep_repr_C PF02742.10 AIF85268.1 - 1.5e-20 72.6 0.3 2.5e-20 71.9 0.2 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.14 AIF85268.1 - 2.4e-13 49.7 0.8 5.4e-13 48.6 0.5 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.2 AIF85268.1 - 0.00042 19.9 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.15 AIF85268.1 - 0.00057 19.4 0.2 0.0015 18.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family IF2_N PF04760.10 AIF85268.1 - 0.00078 19.0 0.7 0.0018 17.9 0.1 1.9 2 1 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Rrf2 PF02082.15 AIF85268.1 - 0.0013 18.8 0.2 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.17 AIF85268.1 - 0.0017 17.9 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.1 AIF85268.1 - 0.0027 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_27 PF13463.1 AIF85268.1 - 0.0034 17.6 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 AIF85268.1 - 0.0063 16.2 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 AIF85268.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_IclR PF09339.5 AIF85268.1 - 0.027 14.0 0.0 0.054 13.0 0.0 1.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2777 PF10949.3 AIF85268.1 - 0.11 12.2 0.2 0.29 10.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) HTH_1 PF00126.22 AIF85268.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family TFIIE_beta PF02186.10 AIF85268.1 - 0.17 11.8 0.6 0.35 10.8 0.1 1.7 2 0 0 2 2 2 0 TFIIE beta subunit core domain Ferritin PF00210.19 AIF85269.1 - 1.8e-17 63.4 3.3 2.1e-17 63.1 2.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AIF85269.1 - 9.7e-09 35.6 2.9 1.1e-08 35.4 2.0 1.1 1 0 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.1 AIF85269.1 - 6.3e-05 22.9 0.5 7.3e-05 22.7 0.4 1.1 1 0 0 1 1 1 1 Ferritin-like domain zinc_ribbon_2 PF13240.1 AIF85270.1 - 0.0022 17.4 3.9 0.019 14.4 2.7 2.0 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AIF85270.1 - 0.0038 17.0 2.7 0.012 15.4 1.9 1.7 1 1 0 1 1 1 1 Double zinc ribbon Cript PF10235.4 AIF85270.1 - 0.0039 17.5 2.0 0.0046 17.2 1.4 1.1 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT PAAR_motif PF05488.8 AIF85270.1 - 0.0046 16.9 0.2 0.0061 16.5 0.1 1.2 1 0 0 1 1 1 1 PAAR motif Med27 PF11571.3 AIF85270.1 - 0.012 15.7 1.8 0.22 11.6 0.0 2.0 1 1 1 2 2 2 0 Mediator complex subunit 27 Nudix_N_2 PF14803.1 AIF85270.1 - 0.028 14.1 1.4 0.49 10.1 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal DiS_P_DiS PF06750.8 AIF85270.1 - 0.033 13.9 0.1 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-ribbon_3 PF13248.1 AIF85270.1 - 0.033 13.3 1.6 1.6 8.0 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 AIF85270.1 - 0.073 12.4 0.7 0.078 12.3 0.5 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zinc-ribbons_6 PF07191.7 AIF85270.1 - 0.11 12.3 0.8 0.19 11.5 0.5 1.4 1 1 0 1 1 1 0 zinc-ribbons GFA PF04828.9 AIF85270.1 - 0.12 12.2 2.4 0.93 9.4 1.7 1.9 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme HypA PF01155.14 AIF85270.1 - 0.22 11.2 1.3 0.3 10.7 0.9 1.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 AIF85270.1 - 1.3 8.7 5.1 7.6 6.3 3.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AIF85270.1 - 1.5 8.3 6.7 2.9 7.4 0.1 2.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 AIF85270.1 - 1.6 8.3 5.3 11 5.6 3.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DUF4032 PF13224.1 AIF85271.1 - 0.0066 16.1 0.4 0.0066 16.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) Histone_HNS PF00816.16 AIF85271.1 - 0.032 14.7 1.5 0.038 14.4 1.0 1.1 1 0 0 1 1 1 0 H-NS histone family PKI PF02827.11 AIF85271.1 - 0.11 12.5 0.5 0.13 12.4 0.3 1.2 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF809 PF05663.6 AIF85271.1 - 4.2 7.2 7.5 4 7.3 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Jiraiya PF15038.1 AIF85272.1 - 0.025 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Jiraiya Lactamase_B PF00753.22 AIF85273.1 - 2.1e-07 30.7 0.1 3.4e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AIF85273.1 - 0.0031 17.1 0.0 0.0043 16.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AIF85273.1 - 0.08 12.6 0.0 0.43 10.2 0.0 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain CbiA PF01656.18 AIF85274.1 - 0.00013 21.4 0.2 0.00022 20.7 0.2 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 AIF85274.1 - 0.00015 21.4 0.2 0.00042 19.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF1611 PF07755.6 AIF85274.1 - 0.00017 20.3 0.1 0.00017 20.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1611) MobB PF03205.9 AIF85274.1 - 0.00062 19.4 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Alk_phosphatase PF00245.15 AIF85274.1 - 0.015 14.0 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase ABC_tran PF00005.22 AIF85275.1 - 2.3e-34 118.6 1.0 3.3e-34 118.1 0.0 1.8 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 AIF85275.1 - 6.4e-25 88.0 6.3 9.5e-25 87.5 4.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 AIF85275.1 - 9.9e-10 38.8 0.4 0.00021 21.3 0.0 2.5 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 AIF85275.1 - 1.5e-07 30.8 0.9 0.00064 19.0 0.0 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 AIF85275.1 - 1.4e-05 25.2 0.7 0.00044 20.3 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.1 AIF85275.1 - 0.00049 19.5 0.0 0.0013 18.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 AIF85275.1 - 0.00064 20.5 0.0 0.0014 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 AIF85275.1 - 0.0024 17.7 0.9 0.021 14.6 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 AIF85275.1 - 0.0034 17.1 0.2 0.017 14.8 0.0 2.3 3 0 0 3 3 1 1 Part of AAA domain AAA_25 PF13481.1 AIF85275.1 - 0.0053 16.1 0.0 0.034 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AIF85275.1 - 0.0059 16.9 0.2 0.028 14.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 AIF85275.1 - 0.0068 15.5 0.6 0.023 13.8 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 AIF85275.1 - 0.0098 15.3 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 AIF85275.1 - 0.016 15.2 3.5 0.023 14.6 0.9 2.5 2 1 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 AIF85275.1 - 0.024 13.3 0.1 0.044 12.4 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.1 AIF85275.1 - 0.028 13.9 0.5 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AIF85275.1 - 0.031 14.5 0.0 0.091 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 AIF85275.1 - 0.04 12.5 1.2 0.63 8.5 0.0 2.9 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Miro PF08477.8 AIF85275.1 - 0.045 14.2 0.2 0.87 10.1 0.0 2.9 3 0 0 3 3 3 0 Miro-like protein MMR_HSR1 PF01926.18 AIF85275.1 - 0.062 13.2 0.3 0.28 11.1 0.2 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.1 AIF85275.1 - 0.083 11.9 0.1 0.64 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_M14 PF00246.19 AIF85276.1 - 5.2e-18 65.6 0.0 9.4e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 AIF85276.1 - 0.0011 17.9 0.1 0.0018 17.2 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 AIF85276.1 - 0.0014 17.8 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Polysacc_deac_1 PF01522.16 AIF85277.1 - 4.6e-09 35.9 0.0 8.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4179 PF13786.1 AIF85278.1 - 0.0077 16.4 1.4 0.016 15.4 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) Trp_oprn_chp PF09534.5 AIF85278.1 - 0.025 14.1 0.3 0.04 13.5 0.2 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4367 PF14285.1 AIF85279.1 - 0.01 15.1 0.2 0.79 9.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4367) DUF2267 PF10025.4 AIF85280.1 - 7.2e-07 29.3 0.0 8.3e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) Bac_DNA_binding PF00216.16 AIF85280.1 - 0.0013 18.6 0.9 0.035 14.1 0.0 2.3 2 1 0 2 2 2 1 Bacterial DNA-binding protein Mmp37 PF09139.6 AIF85280.1 - 0.071 12.1 1.3 0.079 11.9 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 TPR_19 PF14559.1 AIF85280.1 - 0.089 13.1 0.5 0.74 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HMG_CoA_synt_C PF08540.5 AIF85280.1 - 0.16 11.4 1.4 1.4 8.3 0.0 2.0 1 1 1 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF4423 PF14394.1 AIF85280.1 - 0.16 11.4 1.2 0.25 10.8 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) YlbD_coat PF14071.1 AIF85280.1 - 0.41 10.7 3.7 4.2 7.4 0.1 2.2 1 1 1 2 2 2 0 Putative coat protein PepSY PF03413.14 AIF85281.1 - 0.0011 19.5 0.4 0.0023 18.5 0.3 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Med13_C PF06333.7 AIF85281.1 - 0.36 9.3 5.1 0.47 8.9 3.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF1510 PF07423.6 AIF85281.1 - 2 7.7 16.6 0.055 12.8 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 AIF85281.1 - 6.5 4.2 8.0 7.9 4.0 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 AIF85281.1 - 8.8 4.4 7.0 9.3 4.3 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Laminin_II PF06009.7 AIF85282.1 - 0.015 15.0 5.5 0.073 12.8 1.0 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF2884 PF11101.3 AIF85282.1 - 0.019 14.3 10.1 0.036 13.4 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) InvH PF04741.7 AIF85282.1 - 0.025 14.4 2.1 0.044 13.6 1.5 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Ferritin PF00210.19 AIF85282.1 - 0.031 14.0 1.2 0.059 13.1 0.2 1.8 2 0 0 2 2 2 0 Ferritin-like domain LMP PF04778.7 AIF85282.1 - 0.071 12.8 3.5 0.041 13.6 0.8 1.7 2 0 0 2 2 2 0 LMP repeated region Mitofilin PF09731.4 AIF85282.1 - 0.11 11.0 5.2 0.14 10.7 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Apolipoprotein PF01442.13 AIF85282.1 - 0.19 11.2 10.2 0.18 11.2 3.5 2.2 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phyto_Pns9_10 PF05878.6 AIF85282.1 - 0.22 10.4 4.5 0.17 10.8 2.0 1.6 1 1 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF883 PF05957.8 AIF85282.1 - 0.31 11.4 10.6 0.75 10.2 0.9 3.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) KTI12 PF08433.5 AIF85282.1 - 0.46 9.6 4.8 0.25 10.5 2.1 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Clathrin_lg_ch PF01086.12 AIF85282.1 - 0.74 9.6 10.2 0.15 11.9 4.6 1.7 2 1 0 2 2 2 0 Clathrin light chain HisKA_3 PF07730.8 AIF85282.1 - 0.8 10.0 8.7 3.4 8.0 1.1 3.3 2 1 1 3 3 3 0 Histidine kinase DUF1664 PF07889.7 AIF85282.1 - 1.2 8.9 4.7 0.77 9.5 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ApoO PF09769.4 AIF85282.1 - 1.6 8.4 6.2 0.69 9.5 2.3 1.9 2 1 0 2 2 2 0 Apolipoprotein O Phasin_2 PF09361.5 AIF85282.1 - 1.9 8.5 8.7 0.35 10.9 0.8 2.9 2 1 0 2 2 2 0 Phasin protein DUF2229 PF09989.4 AIF85282.1 - 2 7.8 5.0 0.53 9.6 0.6 1.9 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3391 PF11871.3 AIF85282.1 - 2.7 8.1 8.4 1 9.5 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF2564 PF10819.3 AIF85282.1 - 3.1 7.9 10.3 3.9 7.6 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) Troponin PF00992.15 AIF85282.1 - 3.2 7.8 9.0 0.27 11.2 2.9 1.8 2 0 0 2 2 2 0 Troponin TMEM51 PF15345.1 AIF85282.1 - 3.4 7.2 8.9 2.7 7.6 5.2 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 YtxH PF12732.2 AIF85282.1 - 7.8 6.9 6.9 27 5.2 1.7 2.8 2 1 0 2 2 2 0 YtxH-like protein Histone_HNS PF00816.16 AIF85282.1 - 9.9 6.7 9.2 2.6 8.6 3.4 2.2 2 1 0 2 2 2 0 H-NS histone family Cytomega_UL84 PF06284.6 AIF85283.1 - 0.15 10.4 0.1 0.27 9.5 0.1 1.5 1 1 0 1 1 1 0 Cytomegalovirus UL84 protein Pyridox_oxidase PF01243.15 AIF85284.1 - 6.7e-06 26.0 0.0 8.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF385 PF04075.9 AIF85284.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF385) Pyridox_ox_2 PF12900.2 AIF85284.1 - 0.017 14.9 0.0 0.027 14.3 0.0 1.4 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-C2H2_4 PF13894.1 AIF85285.1 - 0.0025 18.0 1.5 0.0038 17.4 1.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger CofC PF01983.11 AIF85285.1 - 0.013 14.5 0.0 0.014 14.3 0.0 1.0 1 0 0 1 1 1 0 Guanylyl transferase CofC like DUF3508 PF12018.3 AIF85285.1 - 0.056 12.4 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) YSIRK_signal PF04650.12 AIF85289.1 - 0.36 10.4 2.5 1 8.9 1.7 1.8 1 0 0 1 1 1 0 YSIRK type signal peptide Cation_efflux PF01545.16 AIF85290.1 - 1.5e-72 244.0 7.0 1.7e-72 243.9 4.8 1.0 1 0 0 1 1 1 1 Cation efflux family TrbC PF04956.8 AIF85291.1 - 0.014 15.3 2.2 0.017 15.1 1.6 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF4199 PF13858.1 AIF85291.1 - 1.7 8.5 5.9 3.2 7.6 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) N6_N4_Mtase PF01555.13 AIF85292.1 - 2.7e-40 138.3 0.0 3.2e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 AIF85292.1 - 6.6e-08 32.6 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.13 AIF85292.1 - 0.042 13.4 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 AIF85293.1 - 7.8e-18 65.0 0.1 1.1e-17 64.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AIF85293.1 - 1.8e-15 56.8 0.1 2.4e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AIF85293.1 - 8.5e-11 41.5 0.3 4.8e-10 39.0 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AIF85293.1 - 2.2e-10 40.8 0.1 4.8e-10 39.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AIF85293.1 - 2.8e-09 37.0 0.0 7.4e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AIF85293.1 - 6.2e-09 35.3 0.8 8e-09 35.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 AIF85293.1 - 8.8e-09 35.7 0.1 1.7e-08 34.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF85293.1 - 1.6e-08 34.9 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AIF85293.1 - 4e-08 33.0 0.2 4.8e-08 32.7 0.2 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 AIF85293.1 - 7.3e-07 28.5 0.1 1.2e-06 27.8 0.1 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AIF85293.1 - 7.6e-07 28.9 0.0 1.2e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AIF85293.1 - 1.5e-06 27.8 0.1 2.1e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 AIF85293.1 - 1.9e-06 28.6 0.0 2.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 AIF85293.1 - 1e-05 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 AIF85293.1 - 1.5e-05 24.2 0.3 2e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_5 PF01795.14 AIF85293.1 - 0.00013 21.4 0.0 0.00092 18.5 0.0 1.9 1 1 1 2 2 2 1 MraW methylase family Cons_hypoth95 PF03602.10 AIF85293.1 - 0.00015 21.1 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.11 AIF85293.1 - 0.00019 21.0 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 AIF85293.1 - 0.00045 19.3 0.0 0.00061 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Spermine_synth PF01564.12 AIF85293.1 - 0.00058 18.8 0.1 0.00093 18.2 0.1 1.3 1 1 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_4 PF02390.12 AIF85293.1 - 0.00081 18.4 0.1 0.013 14.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_3 PF01596.12 AIF85293.1 - 0.00096 18.2 0.3 0.0017 17.4 0.2 1.5 1 1 0 1 1 1 1 O-methyltransferase FmrO PF07091.6 AIF85293.1 - 0.0014 17.6 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 AIF85293.1 - 0.0017 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 AIF85293.1 - 0.0026 17.4 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF633 PF04816.7 AIF85293.1 - 0.0087 15.4 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) AviRa PF11599.3 AIF85293.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa POR PF01558.13 AIF85293.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DOT1 PF08123.8 AIF85293.1 - 0.025 13.8 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 FtsJ PF01728.14 AIF85293.1 - 0.031 14.2 0.1 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.12 AIF85293.1 - 0.032 13.1 0.1 0.39 9.6 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family NodS PF05401.6 AIF85293.1 - 0.034 13.5 0.1 0.069 12.5 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) TylF PF05711.6 AIF85293.1 - 0.034 13.2 0.1 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) GidB PF02527.10 AIF85293.1 - 0.043 12.9 0.1 0.063 12.4 0.1 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MetW PF07021.7 AIF85293.1 - 0.061 12.6 0.2 0.086 12.1 0.2 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW rRNA_methylase PF06962.7 AIF85293.1 - 0.097 12.3 0.1 5.5 6.6 0.0 2.3 1 1 1 2 2 2 0 Putative rRNA methylase TehB PF03848.9 AIF85293.1 - 0.099 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF475 PF04332.10 AIF85294.1 - 0.0018 17.9 0.4 0.0021 17.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF475) FUSC_2 PF13515.1 AIF85294.1 - 0.015 15.2 4.7 0.019 14.8 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein-like NnrS PF05940.7 AIF85294.1 - 0.016 14.1 0.8 0.023 13.6 0.6 1.3 1 1 0 1 1 1 0 NnrS protein MscS_TM PF12794.2 AIF85294.1 - 0.038 12.6 0.2 0.042 12.4 0.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Phage_holin_4 PF05105.7 AIF85294.1 - 0.1 12.2 2.8 0.075 12.7 1.0 1.4 1 1 0 1 1 1 0 Holin family IncA PF04156.9 AIF85294.1 - 0.11 12.0 1.1 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 IncA protein DUF3429 PF11911.3 AIF85294.1 - 0.19 11.6 3.8 7.3 6.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3429) DUF2178 PF09946.4 AIF85294.1 - 0.27 11.0 5.4 0.55 9.9 3.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2178) RseC_MucC PF04246.7 AIF85294.1 - 0.44 10.1 4.5 0.08 12.5 0.4 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Bacteriocin_IIc PF10439.4 AIF85294.1 - 0.87 9.7 4.3 1.3 9.1 3.0 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rab5ip PF07019.7 AIF85294.1 - 1.8 8.7 11.7 7.8 6.7 3.6 2.9 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) Yip1 PF04893.12 AIF85294.1 - 4.7 6.6 9.4 10 5.5 6.5 1.6 1 1 0 1 1 1 0 Yip1 domain Gly-zipper_YMGG PF13441.1 AIF85294.1 - 6.5 6.3 11.3 9.9 5.7 7.8 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF2273 PF10031.4 AIF85294.1 - 8.8 6.0 10.5 3.2 7.4 1.9 2.6 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF3682 PF12446.3 AIF85297.1 - 0.015 15.5 1.4 0.022 15.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3385 PF11865.3 AIF85297.1 - 0.061 13.2 0.1 0.081 12.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) NUT_C PF12882.2 AIF85297.1 - 0.13 11.8 1.1 0.29 10.7 0.7 1.6 1 1 1 2 2 2 0 NUT protein C terminal DUF4268 PF14088.1 AIF85298.1 - 0.0067 16.0 2.0 0.013 15.1 0.2 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4268) HSDR_N_2 PF13588.1 AIF85299.1 - 0.031 14.0 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF2597 PF10772.4 AIF85300.1 - 0.061 13.2 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2597) vATP-synt_AC39 PF01992.11 AIF85301.1 - 9.1e-40 136.7 7.9 1.1e-39 136.5 5.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit PP1_inhibitor PF05361.7 AIF85301.1 - 0.0054 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Zn_ribbon_2 PF12674.2 AIF85302.1 - 2.7e-22 78.9 0.0 3e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Putative zinc ribbon domain Sigma_reg_N PF13800.1 AIF85302.1 - 0.081 12.9 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal V_ATPase_I PF01496.14 AIF85303.1 - 3.3e-40 137.6 7.8 2.2e-39 134.9 5.4 2.1 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family PilN PF05137.8 AIF85303.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) DUF1192 PF06698.6 AIF85303.1 - 0.47 10.2 2.8 0.56 10.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ATP-synt_C PF00137.16 AIF85304.1 - 2.7e-18 65.6 18.1 2.7e-18 65.6 12.6 2.1 2 0 0 2 2 2 1 ATP synthase subunit C SepZ PF06066.6 AIF85304.1 - 0.087 12.8 7.4 0.15 12.0 4.8 1.7 1 1 1 2 2 2 0 SepZ Cyd_oper_YbgE PF09600.5 AIF85304.1 - 1.8 8.7 6.9 0.34 11.1 1.8 2.0 1 1 1 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF3693 PF12472.3 AIF85304.1 - 7.1 6.3 6.6 1.4 8.5 0.3 2.4 1 1 1 2 2 2 0 Phage related protein ATP-synt_B PF00430.13 AIF85305.1 - 0.039 13.7 2.6 0.038 13.7 1.8 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) VASP_tetra PF08776.6 AIF85305.1 - 0.15 11.3 1.6 0.17 11.2 1.1 1.4 1 1 0 1 1 1 0 VASP tetramerisation domain ATP-synt_D PF01813.12 AIF85306.1 - 1.8e-50 171.2 6.4 2.3e-50 170.8 4.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit D PerC PF06069.6 AIF85306.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 PerC transcriptional activator Skp1_POZ PF03931.10 AIF85306.1 - 0.091 12.8 0.3 4.6 7.4 0.0 2.6 2 1 1 3 3 3 0 Skp1 family, tetramerisation domain ATP-synt_ab PF00006.20 AIF85307.1 - 1.1e-62 211.4 0.0 1.7e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AIF85307.1 - 1.8e-12 47.6 0.0 3.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AIF85307.1 - 7.3e-07 29.3 0.6 1.9e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AIF85307.1 - 0.0034 17.2 0.4 0.018 14.8 0.2 2.2 2 0 0 2 2 2 1 HAS barrel domain ATP-synt_ab PF00006.20 AIF85308.1 - 3.7e-95 317.4 0.0 4.8e-95 317.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AIF85308.1 - 7e-18 65.1 0.8 1.7e-17 63.8 0.6 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AIF85308.1 - 1.7e-13 50.5 0.7 4.6e-13 49.1 0.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.1 AIF85308.1 - 0.0062 16.2 0.0 0.06 13.1 0.0 2.5 1 1 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AIF85308.1 - 0.039 14.0 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1409 PF07197.7 AIF85308.1 - 0.12 12.5 0.1 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) vATP-synt_E PF01991.13 AIF85309.1 - 8.2e-25 87.2 9.5 2e-24 85.9 5.7 1.8 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit Phage_antitermQ PF06530.7 AIF85309.1 - 0.00079 18.9 0.1 0.0042 16.6 0.0 1.9 2 0 0 2 2 2 1 Phage antitermination protein Q PEPcase PF00311.12 AIF85309.1 - 0.036 11.9 0.3 0.044 11.6 0.2 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DWNN PF08783.6 AIF85309.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 DWNN domain DUF4407 PF14362.1 AIF85309.1 - 0.19 10.6 4.8 0.25 10.2 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Lge1 PF11488.3 AIF85309.1 - 2 8.6 5.9 3.1 8.0 0.7 2.9 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 Phage_GP20 PF06810.6 AIF85309.1 - 4 6.8 8.2 1.3 8.4 1.6 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Mut7-C PF01927.11 AIF85310.1 - 1.6e-39 135.2 0.0 1.8e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain CBS PF00571.23 AIF85311.1 - 2.4e-26 91.2 3.0 9e-13 47.7 0.2 2.5 2 0 0 2 2 2 2 CBS domain TF_Zn_Ribbon PF08271.7 AIF85311.1 - 0.092 12.0 2.3 0.25 10.7 1.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding FbpA PF05833.6 AIF85312.1 - 3.8e-35 121.3 3.3 5.8e-35 120.7 2.3 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 AIF85312.1 - 2.7e-19 68.8 0.0 1e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Mod_r PF07200.8 AIF85312.1 - 0.57 10.0 4.9 0.27 11.1 1.0 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Trns_repr_metal PF02583.12 AIF85312.1 - 1.9 8.7 9.4 3.7 7.8 0.4 3.6 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor Polysacc_synt_3 PF13440.1 AIF85313.1 - 0.0024 17.3 1.0 0.0024 17.3 0.7 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein VIT1 PF01988.14 AIF85313.1 - 0.0098 15.4 0.2 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 VIT family G3P_acyltransf PF02660.10 AIF85313.1 - 0.03 13.8 2.5 0.035 13.6 1.8 1.0 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase DUF4131 PF13567.1 AIF85313.1 - 0.064 12.6 0.2 0.073 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) IncA PF04156.9 AIF85313.1 - 0.11 12.0 1.2 0.13 11.8 0.9 1.0 1 0 0 1 1 1 0 IncA protein AdoMet_Synthase PF01941.14 AIF85313.1 - 0.12 10.8 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DUF2798 PF11391.3 AIF85313.1 - 0.25 11.1 6.1 5.3 6.8 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) DUF2109 PF09882.4 AIF85313.1 - 3.4 7.6 9.1 4 7.4 3.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2109) Lactamase_B_2 PF12706.2 AIF85314.1 - 1.7e-06 27.7 0.0 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AIF85314.1 - 0.0011 18.7 0.0 0.0072 16.0 0.0 2.3 2 1 1 3 3 3 1 Beta-lactamase superfamily domain CDC48_N PF02359.13 AIF85315.1 - 3e-23 81.5 1.1 6.6e-23 80.4 0.8 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 AIF85315.1 - 5.5e-10 38.7 0.0 1.6e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 PUA PF01472.15 AIF85315.1 - 0.0003 20.4 0.5 5.3 6.8 0.0 4.1 2 1 2 4 4 4 2 PUA domain YCII PF03795.9 AIF85317.1 - 0.11 12.6 0.1 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 YCII-related domain HTH_34 PF13601.1 AIF85317.1 - 0.13 12.3 0.2 0.58 10.2 0.1 2.0 1 1 1 2 2 2 0 Winged helix DNA-binding domain PyrI PF01948.13 AIF85318.1 - 2.9e-36 123.3 2.0 2.9e-36 123.3 1.4 1.4 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.10 AIF85318.1 - 1.2e-16 59.9 1.0 2e-16 59.1 0.7 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.2 AIF85319.1 - 0.00038 20.2 6.8 0.0015 18.3 4.9 1.8 1 1 1 2 2 2 2 Double zinc ribbon Ribosomal_L37e PF01907.14 AIF85319.1 - 0.033 13.9 6.4 0.32 10.8 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e Ribosomal_S27 PF01599.14 AIF85319.1 - 0.092 12.5 0.4 0.092 12.5 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein S27a NMD3 PF04981.8 AIF85319.1 - 0.15 11.1 3.7 0.49 9.4 0.5 2.1 1 1 1 2 2 2 0 NMD3 family zinc_ribbon_2 PF13240.1 AIF85319.1 - 0.54 9.8 8.1 4.5 6.8 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain XPA_N PF01286.13 AIF85319.1 - 1.5 8.5 10.9 1.6 8.4 1.3 3.8 3 1 1 4 4 4 0 XPA protein N-terminal DnaJ_CXXCXGXG PF00684.14 AIF85319.1 - 1.7 8.7 12.0 63 3.7 8.6 2.4 1 1 1 2 2 2 0 DnaJ central domain zf-ribbon_3 PF13248.1 AIF85319.1 - 3.4 6.9 13.2 0.58 9.4 1.4 2.8 2 2 1 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 AIF85319.1 - 3.9 7.8 6.9 2.8e+02 1.9 4.8 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_3 PF14369.1 AIF85319.1 - 5.3 7.1 0.0 5.3 7.1 0.0 3.3 3 1 0 3 3 3 0 zinc-finger AhpC-TSA PF00578.16 AIF85320.1 - 4.2e-15 55.5 0.1 6.8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AIF85320.1 - 1.6e-14 53.6 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 AIF85320.1 - 2e-09 37.4 0.3 3.6e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin-like GSHPx PF00255.14 AIF85320.1 - 0.00049 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase SCO1-SenC PF02630.9 AIF85320.1 - 0.0062 16.1 0.2 0.37 10.3 0.0 2.2 1 1 1 2 2 2 1 SCO1/SenC Thioredoxin_2 PF13098.1 AIF85320.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.15 AIF85320.1 - 0.047 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DsbD PF02683.10 AIF85321.1 - 5.6e-46 156.7 18.3 2.6e-36 125.2 9.6 2.0 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 AIF85321.1 - 2.5e-07 30.6 18.8 3.5e-07 30.1 13.0 1.3 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2910 PF11139.3 AIF85321.1 - 0.14 11.2 15.4 0.4 9.7 10.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) MraY_sig1 PF10555.4 AIF85321.1 - 5.8 6.4 9.0 11 5.5 0.5 2.9 2 0 0 2 2 2 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 HTH_5 PF01022.15 AIF85323.1 - 1.7e-08 34.0 0.0 2.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.14 AIF85323.1 - 3.2e-05 23.5 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AIF85323.1 - 4.8e-05 23.0 0.0 6.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AIF85323.1 - 0.0022 17.3 0.1 0.0033 16.7 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding FaeA PF04703.7 AIF85323.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 FaeA-like protein HTH_34 PF13601.1 AIF85323.1 - 0.028 14.4 0.1 0.05 13.6 0.0 1.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.7 AIF85323.1 - 0.061 13.1 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_45 PF14947.1 AIF85323.1 - 0.065 13.0 0.1 0.093 12.5 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_11 PF08279.7 AIF85323.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 HTH domain MarR PF01047.17 AIF85323.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.2 AIF85323.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 MarR family CbiA PF01656.18 AIF85324.1 - 3.5e-24 85.2 0.0 5.1e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AIF85324.1 - 1.2e-14 54.5 0.0 8.7e-11 41.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain MipZ PF09140.6 AIF85324.1 - 8.6e-09 34.8 0.0 2e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.10 AIF85324.1 - 4.1e-05 22.7 0.0 0.00024 20.2 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.6 AIF85324.1 - 0.0002 20.4 0.8 0.00027 20.0 0.1 1.5 2 0 0 2 2 2 1 VirC1 protein SRP54 PF00448.17 AIF85324.1 - 0.0014 18.1 0.2 0.0059 16.0 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 AIF85324.1 - 0.0041 16.3 0.0 0.016 14.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 AIF85324.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.9 AIF85324.1 - 0.073 12.7 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 AIF85324.1 - 0.094 12.4 0.2 0.27 11.0 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain LpxK PF02606.9 AIF85324.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase YhjQ PF06564.7 AIF85324.1 - 0.14 11.4 0.0 2.3 7.4 0.0 2.0 2 0 0 2 2 2 0 YhjQ protein KaiC PF06745.8 AIF85325.1 - 9e-26 90.3 0.0 1.4e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AIF85325.1 - 9.1e-07 28.4 0.0 2.7e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AIF85325.1 - 5.5e-06 26.5 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Guanylate_cyc PF00211.15 AIF85325.1 - 1.9e-05 24.1 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_19 PF13245.1 AIF85325.1 - 3.7e-05 23.3 0.0 0.00016 21.3 0.0 2.2 1 1 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 AIF85325.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain GvpD PF07088.6 AIF85325.1 - 0.0021 16.4 0.0 0.0089 14.3 0.0 1.8 1 1 0 1 1 1 1 GvpD gas vesicle protein IstB_IS21 PF01695.12 AIF85325.1 - 0.0088 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 AIF85325.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 AIF85325.1 - 0.064 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MEDS PF14417.1 AIF85325.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_29 PF13555.1 AIF85325.1 - 0.099 12.1 0.8 0.64 9.5 0.0 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA PF00004.24 AIF85325.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AIF85325.1 - 0.15 11.4 0.0 0.32 10.4 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain Zot PF05707.7 AIF85325.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DEAD PF00270.24 AIF85326.1 - 2.5e-51 173.5 0.4 3.4e-49 166.5 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AIF85326.1 - 1.7e-27 95.0 0.4 1.9e-26 91.7 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AIF85326.1 - 3.4e-05 22.7 0.0 5.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_RecD PF05127.9 AIF85326.1 - 0.00035 20.2 0.1 0.0017 18.0 0.0 2.0 1 1 1 2 2 2 1 Helicase ResIII PF04851.10 AIF85326.1 - 0.00039 20.2 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AIF85326.1 - 0.00057 18.4 0.0 0.041 12.3 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 AIF85326.1 - 0.0034 16.4 0.9 0.0073 15.4 0.2 1.8 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 AIF85326.1 - 0.0053 16.5 0.2 0.57 9.9 0.1 2.6 2 1 0 2 2 2 1 Flavivirus DEAD domain AAA_30 PF13604.1 AIF85326.1 - 0.0058 16.2 0.5 0.079 12.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain LuxC PF05893.9 AIF85326.1 - 0.066 11.9 0.1 0.32 9.6 0.0 1.9 1 1 1 2 2 2 0 Acyl-CoA reductase (LuxC) zinc_ribbon_2 PF13240.1 AIF85327.1 - 9.5e-06 24.9 4.8 1.5e-05 24.3 3.3 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 AIF85327.1 - 1.9e-05 23.7 3.6 2.9e-05 23.1 2.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AIF85327.1 - 0.00015 21.4 0.7 0.00022 20.9 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon DUF2116 PF09889.4 AIF85327.1 - 0.0022 17.7 2.4 0.0043 16.8 1.6 1.5 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) UPF0547 PF10571.4 AIF85327.1 - 0.078 12.6 4.3 0.13 11.9 3.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 YhfH PF14149.1 AIF85327.1 - 0.54 10.1 4.2 7.6 6.4 0.0 2.3 1 1 1 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.1 AIF85328.1 - 1.2e-05 24.2 4.2 2.3e-05 23.4 2.9 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AIF85328.1 - 2.3e-05 24.1 1.0 3.7e-05 23.4 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 AIF85328.1 - 3.9e-05 22.9 10.5 0.0002 20.7 3.7 1.9 1 1 1 2 2 2 2 zinc-ribbon domain zf-DHHC PF01529.15 AIF85328.1 - 0.007 15.7 0.0 0.007 15.7 0.0 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Nudix_N_2 PF14803.1 AIF85328.1 - 0.018 14.7 5.3 0.83 9.4 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal RNA_POL_M_15KD PF02150.11 AIF85328.1 - 0.39 10.4 4.7 10 5.9 0.4 2.9 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.4 AIF85328.1 - 0.61 9.8 3.0 1.4 8.7 2.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 AIF85328.1 - 1.4 8.8 6.8 34 4.3 0.2 2.7 3 1 1 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like GFA PF04828.9 AIF85328.1 - 4.2 7.3 5.7 17 5.4 0.1 2.8 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Polyketide_cyc2 PF10604.4 AIF85329.1 - 2.2e-05 24.6 0.0 2.6e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COX7C PF02935.11 AIF85330.1 - 0.33 10.7 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Fil_haemagg PF05594.9 AIF85330.1 - 1.9 8.8 16.2 2.2e+02 2.2 11.0 3.3 1 1 0 1 1 1 0 Haemagluttinin repeat Spt4 PF06093.8 AIF85331.1 - 0.0052 16.6 1.6 0.0057 16.5 1.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF983 PF06170.7 AIF85331.1 - 0.033 14.2 0.7 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) GATA PF00320.22 AIF85331.1 - 0.052 12.9 3.1 0.21 10.9 0.2 2.1 2 0 0 2 2 2 0 GATA zinc finger TF_Zn_Ribbon PF08271.7 AIF85331.1 - 0.082 12.2 3.0 2.2 7.6 2.1 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding DUF35_N PF12172.3 AIF85331.1 - 0.23 11.4 0.1 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C2H2_3 PF13878.1 AIF85331.1 - 0.3 10.6 6.1 0.31 10.6 0.3 2.0 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Ribosomal_L40e PF01020.12 AIF85331.1 - 0.33 10.5 2.0 0.17 11.4 0.3 1.5 1 1 0 1 1 1 0 Ribosomal L40e family ADK_lid PF05191.9 AIF85331.1 - 1.1 8.9 4.7 6.1 6.5 3.2 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid AAA_18 PF13238.1 AIF85332.1 - 4.9e-12 46.2 0.1 6.7e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIF85332.1 - 4.1e-08 34.0 0.1 5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AIF85332.1 - 4.5e-05 23.6 0.1 0.00011 22.4 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AIF85332.1 - 0.00094 18.2 0.1 0.0018 17.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 AIF85332.1 - 0.0011 18.6 0.3 0.0067 16.1 0.0 2.2 1 1 0 1 1 1 1 NTPase AAA_22 PF13401.1 AIF85332.1 - 0.0056 16.8 0.1 0.026 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 AIF85332.1 - 0.0068 16.2 0.2 0.29 10.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_19 PF13245.1 AIF85332.1 - 0.0078 15.9 0.3 0.023 14.4 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain Cytidylate_kin2 PF13189.1 AIF85332.1 - 0.012 15.5 0.2 1.4 8.8 0.2 2.6 1 1 0 1 1 1 0 Cytidylate kinase-like family MobB PF03205.9 AIF85332.1 - 0.02 14.5 1.4 0.88 9.2 0.3 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 AIF85332.1 - 0.042 13.0 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ArgK PF03308.11 AIF85332.1 - 0.064 12.0 0.7 0.1 11.3 0.1 1.6 2 0 0 2 2 2 0 ArgK protein UPF0175 PF03683.8 AIF85332.1 - 0.11 12.0 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) DUF4177 PF13783.1 AIF85333.1 - 0.14 11.8 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) AHSA1 PF08327.6 AIF85334.1 - 0.04 14.0 0.0 0.044 13.8 0.0 1.0 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein DUF956 PF06115.6 AIF85334.1 - 0.061 12.9 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Lsm_C PF14894.1 AIF85335.1 - 7.2e-21 73.4 0.9 2.3e-20 71.8 0.1 1.9 2 0 0 2 2 2 1 Lsm C-terminal SM-ATX PF14438.1 AIF85335.1 - 1e-05 25.3 0.1 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 AIF85335.1 - 1.8e-05 24.2 0.2 2.9e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 AIF85335.1 - 0.00054 19.7 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 Scd6-like Sm domain TGT PF01702.13 AIF85336.1 - 6.2e-46 156.6 0.0 9.9e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Endonuclease_5 PF04493.9 AIF85337.1 - 5.7e-50 169.5 0.0 7.2e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 AIF85337.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 Fer4 PF00037.22 AIF85339.1 - 6.8e-13 47.6 10.8 1e-07 31.2 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 AIF85339.1 - 8.9e-11 41.1 10.2 1.3e-05 24.8 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AIF85339.1 - 3.7e-10 40.0 4.5 5.1e-10 39.5 3.1 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIF85339.1 - 4.7e-09 35.6 9.2 0.00028 20.6 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AIF85339.1 - 5.1e-09 35.7 3.5 7.6e-09 35.2 2.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AIF85339.1 - 7.7e-08 32.0 1.4 1.1e-07 31.5 1.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIF85339.1 - 1.3e-07 31.7 12.8 4e-06 26.9 4.1 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 AIF85339.1 - 5.4e-07 29.8 5.6 0.0038 17.5 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 AIF85339.1 - 6.7e-07 29.7 9.9 9.6e-05 22.8 1.0 2.4 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_4 PF12800.2 AIF85339.1 - 2.9e-06 27.1 8.6 0.01 16.1 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AIF85339.1 - 1.2e-05 25.2 3.6 2.4e-05 24.2 2.5 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 AIF85339.1 - 8.8e-05 23.1 1.8 0.21 12.3 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 AIF85339.1 - 0.00018 21.7 6.1 0.0045 17.2 4.2 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.2 AIF85339.1 - 0.00072 19.9 15.1 0.071 13.7 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 AIF85339.1 - 0.0036 17.6 7.1 0.23 11.9 1.8 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Methyltransf_23 PF13489.1 AIF85341.1 - 0.0036 17.0 0.0 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AIF85341.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.1 AIF85342.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 AIF85342.1 - 0.0071 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 AIF85342.1 - 0.033 13.7 0.0 0.072 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain BNR_2 PF13088.1 AIF85343.1 - 4.4e-05 22.9 0.0 0.0064 15.8 0.0 2.2 1 1 0 1 1 1 1 BNR repeat-like domain Parvo_coat_N PF08398.5 AIF85343.1 - 0.076 12.8 0.0 23 4.8 0.0 3.1 4 0 0 4 4 4 0 Parvovirus coat protein VP1 Beta-Casp PF10996.3 AIF85345.1 - 4.9e-19 68.5 0.0 1.5e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_2 PF12706.2 AIF85345.1 - 2.1e-12 46.9 0.0 4.3e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AIF85345.1 - 8e-11 41.9 0.0 1.2e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily RMMBL PF07521.7 AIF85345.1 - 9.9e-07 28.4 0.2 4.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AIF85345.1 - 8.9e-06 25.5 0.1 2.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CsgE PF10627.4 AIF85345.1 - 0.079 12.7 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Curli assembly protein CsgE DUF581 PF04570.9 AIF85346.1 - 0.14 11.4 1.1 0.22 10.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF581) DUF2039 PF10217.4 AIF85346.1 - 0.2 11.6 2.8 0.26 11.3 1.7 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Bactofilin PF04519.8 AIF85347.1 - 0.00089 19.2 7.7 0.07 13.1 1.4 2.1 1 1 1 2 2 2 2 Polymer-forming cytoskeletal GTP_EFTU_D4 PF14578.1 AIF85347.1 - 7 6.3 9.5 3.5 7.3 2.8 2.5 1 1 2 3 3 3 0 Elongation factor Tu domain 4 tRNA-synt_1e PF01406.14 AIF85348.1 - 6.1e-127 422.8 0.1 1e-126 422.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AIF85348.1 - 2.6e-15 56.0 1.5 1e-07 30.9 0.3 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AIF85348.1 - 3.2e-09 35.3 0.0 2.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 AIF85348.1 - 3.8e-08 33.4 2.0 3.8e-08 33.4 1.4 2.5 3 0 0 3 3 3 1 DALR domain tRNA-synt_1f PF01921.13 AIF85348.1 - 3.5e-07 29.2 0.1 0.003 16.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.14 AIF85348.1 - 0.0031 16.3 0.0 0.06 12.1 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 AIF85348.1 - 0.0044 15.7 0.7 0.4 9.3 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain Rieske PF00355.21 AIF85349.1 - 7.8e-14 51.0 0.0 8.2e-14 50.9 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AIF85349.1 - 2.4e-12 46.4 0.0 2.7e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain VIT1 PF01988.14 AIF85350.1 - 0.0042 16.6 5.1 0.16 11.4 1.0 2.1 2 0 0 2 2 2 2 VIT family ABC2_membrane_2 PF12679.2 AIF85350.1 - 0.062 12.1 0.5 0.086 11.6 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AdoHcyase_NAD PF00670.16 AIF85351.1 - 2.5e-51 173.7 0.1 5.6e-51 172.6 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 AIF85351.1 - 9.7e-51 172.2 0.0 1.1e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 AIF85351.1 - 6.1e-10 38.5 0.0 1.6e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AIF85351.1 - 2.7e-05 23.6 0.0 0.00016 21.0 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 AIF85351.1 - 0.0001 21.8 0.7 0.00031 20.3 0.5 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 AIF85351.1 - 0.0015 18.4 0.0 0.0046 16.9 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain PspA_IM30 PF04012.7 AIF85351.1 - 0.069 12.4 0.6 0.1 11.9 0.4 1.2 1 0 0 1 1 1 0 PspA/IM30 family tRNA-synt_1g PF09334.6 AIF85352.1 - 2.9e-132 441.0 0.0 3.6e-132 440.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AIF85352.1 - 1.3e-15 56.4 0.7 5.3e-06 24.7 0.0 3.8 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AIF85352.1 - 4.3e-14 52.5 0.1 6.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AIF85352.1 - 2.9e-10 39.7 0.1 0.00016 20.8 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 AIF85352.1 - 0.0025 16.5 0.0 0.098 11.3 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) zf-ribbon_3 PF13248.1 AIF85352.1 - 0.0061 15.7 5.0 0.53 9.5 3.5 2.4 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AIF85352.1 - 0.42 10.4 5.2 0.75 9.6 3.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_L37e PF01907.14 AIF85352.1 - 0.65 9.8 2.4 3.1 7.6 1.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e CTP_transf_2 PF01467.21 AIF85353.1 - 6e-15 55.6 0.0 8.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase HIGH_NTase1 PF05636.6 AIF85353.1 - 0.001 18.2 0.0 0.074 12.0 0.0 2.1 2 0 0 2 2 2 2 HIGH Nucleotidyl Transferase Citrate_ly_lig PF08218.6 AIF85353.1 - 0.0018 17.7 0.0 0.16 11.4 0.0 2.7 2 1 0 2 2 2 1 Citrate lyase ligase C-terminal domain ATP-sulfurylase PF01747.12 AIF85353.1 - 0.018 14.3 0.0 0.59 9.3 0.0 2.1 2 0 0 2 2 2 0 ATP-sulfurylase zf-CSL PF05207.8 AIF85354.1 - 2.6e-05 23.6 1.5 3.1e-05 23.3 1.0 1.2 1 0 0 1 1 1 1 CSL zinc finger Lar_restr_allev PF14354.1 AIF85354.1 - 0.00013 22.2 1.3 0.00015 21.9 0.9 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 AIF85354.1 - 0.0021 17.8 1.8 0.0027 17.4 1.2 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.8 AIF85354.1 - 0.014 15.1 1.4 0.014 15.0 1.0 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 AIF85354.1 - 0.022 14.3 1.5 0.037 13.6 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Cys_rich_CPXG PF14255.1 AIF85354.1 - 0.032 14.0 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich CPXCG zf-TFIIB PF13453.1 AIF85354.1 - 0.035 13.3 0.8 0.071 12.3 0.6 1.6 1 1 0 1 1 1 0 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.7 AIF85354.1 - 0.045 13.0 1.0 0.075 12.3 0.7 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding DUF2072 PF09845.4 AIF85354.1 - 0.08 12.8 0.6 0.11 12.4 0.4 1.3 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zinc_ribbon_4 PF13717.1 AIF85354.1 - 0.081 12.6 2.1 0.14 11.8 1.5 1.4 1 1 0 1 1 1 0 zinc-ribbon domain DUF845 PF05820.6 AIF85354.1 - 0.13 11.9 0.1 0.15 11.7 0.1 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF845) DZR PF12773.2 AIF85354.1 - 0.17 11.6 2.6 0.24 11.2 1.8 1.4 1 1 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 AIF85354.1 - 0.21 11.6 5.0 0.39 10.8 3.4 1.5 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-DNL PF05180.7 AIF85354.1 - 0.21 11.2 2.3 0.28 10.9 1.6 1.3 1 0 0 1 1 1 0 DNL zinc finger FdhE PF04216.7 AIF85354.1 - 0.27 10.9 1.7 0.27 10.9 1.2 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation TFIIS_C PF01096.13 AIF85354.1 - 0.35 10.5 2.1 3.9 7.1 1.4 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 AIF85354.1 - 0.8 9.7 5.1 1 9.3 0.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Sgf11 PF08209.6 AIF85354.1 - 7.4 5.9 7.3 0.84 9.0 0.1 2.3 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) MS_channel PF00924.13 AIF85355.1 - 1e-07 31.5 1.4 3.1e-07 29.9 0.9 1.7 1 1 0 1 1 1 1 Mechanosensitive ion channel Pirin PF02678.11 AIF85357.1 - 3.9e-34 116.7 0.8 7.7e-34 115.7 0.5 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 AIF85357.1 - 2.5e-07 30.7 0.1 2.9e-05 24.0 0.0 2.5 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 AIF85357.1 - 1e-06 28.0 0.5 1e-06 28.0 0.4 2.8 3 1 0 3 3 3 1 Cupin domain Gly_kinase PF02595.10 AIF85357.1 - 0.051 12.2 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycerate kinase family FMN_red PF03358.10 AIF85358.1 - 4.6e-29 100.8 0.1 5.5e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AIF85358.1 - 3.2e-09 36.6 0.0 4.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 AIF85358.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Usp PF00582.21 AIF85358.1 - 0.023 14.9 0.2 0.037 14.2 0.2 1.3 1 0 0 1 1 1 0 Universal stress protein family Trypsin_2 PF13365.1 AIF85359.1 - 1e-23 83.6 1.5 1e-23 83.6 1.0 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 AIF85359.1 - 3.6e-17 62.0 0.2 1.5e-15 56.7 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.21 AIF85359.1 - 1.9e-14 53.8 0.1 3.6e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Trypsin PDZ PF00595.19 AIF85359.1 - 2.2e-05 24.5 0.1 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 AIF85359.1 - 0.0029 16.1 0.8 0.6 8.4 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Tricorn_PDZ PF14685.1 AIF85359.1 - 0.0048 16.6 0.1 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Tricorn protease PDZ domain SUI1 PF01253.17 AIF85360.1 - 1.2e-17 63.4 0.5 1.5e-17 63.1 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.9 AIF85360.1 - 0.086 13.0 0.1 0.096 12.9 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) SRI PF08236.6 AIF85360.1 - 0.17 11.8 0.6 0.24 11.3 0.4 1.3 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain zf-met PF12874.2 AIF85361.1 - 0.00082 19.4 0.9 0.0013 18.8 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 AIF85361.1 - 0.0027 17.8 0.2 0.0035 17.5 0.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger DUF629 PF04780.7 AIF85361.1 - 0.0051 15.4 0.2 0.0051 15.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 AIF85361.1 - 0.012 15.9 0.2 0.015 15.6 0.2 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AIF85361.1 - 0.028 14.3 0.3 0.04 13.8 0.2 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AIF85361.1 - 0.029 14.5 1.4 0.058 13.5 1.0 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 AIF85361.1 - 1.1 9.3 3.6 6.9 6.8 2.6 1.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MarR PF01047.17 AIF85362.1 - 2.5e-06 27.1 0.1 4.9e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 MarR family DUF2250 PF10007.4 AIF85362.1 - 8.6e-06 25.5 0.0 0.00027 20.7 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) MarR_2 PF12802.2 AIF85362.1 - 4.9e-05 22.9 0.0 0.00014 21.4 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 AIF85362.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AIF85362.1 - 0.0022 17.7 0.1 0.0056 16.4 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain RPA_C PF08784.6 AIF85362.1 - 0.0025 18.1 1.9 0.0053 17.1 1.3 1.4 1 0 0 1 1 1 1 Replication protein A C terminal TrmB PF01978.14 AIF85362.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 AIF85362.1 - 0.0086 16.1 0.4 0.15 12.2 0.1 2.6 3 0 0 3 3 2 1 Transcriptional regulator HTH_5 PF01022.15 AIF85362.1 - 0.012 15.2 0.3 0.03 13.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family PaaX PF07848.7 AIF85362.1 - 0.018 15.0 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 PaaX-like protein HxlR PF01638.12 AIF85362.1 - 0.028 14.0 0.2 0.077 12.6 0.1 1.8 1 0 0 1 1 1 0 HxlR-like helix-turn-helix GntR PF00392.16 AIF85362.1 - 0.039 13.3 0.1 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.5 AIF85362.1 - 0.078 12.5 0.2 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.7 AIF85362.1 - 0.087 12.4 0.1 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 HTH domain FeoC PF09012.5 AIF85362.1 - 0.089 12.5 0.2 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator Proteasome PF00227.21 AIF85364.1 - 1.7e-48 164.4 0.4 2.1e-48 164.1 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 AIF85365.1 - 2e-41 141.4 0.0 2.4e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HxlR PF01638.12 AIF85366.1 - 7.3e-28 96.0 1.1 8.9e-28 95.7 0.7 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.9 AIF85366.1 - 0.0026 17.4 0.1 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.1 AIF85366.1 - 0.0062 16.5 0.1 0.0096 15.9 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 AIF85366.1 - 0.042 13.5 0.2 0.089 12.5 0.2 1.5 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.2 AIF85366.1 - 0.067 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 AIF85366.1 - 0.084 12.2 0.8 0.15 11.4 0.5 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF4231 PF14015.1 AIF85368.1 - 0.028 14.3 0.4 9 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Polysacc_synt_C PF14667.1 AIF85368.1 - 0.099 12.4 3.5 0.58 9.9 0.5 2.7 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF1081 PF06448.6 AIF85368.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) HTH_45 PF14947.1 AIF85369.1 - 6.8e-09 35.4 0.6 8.9e-09 35.0 0.4 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix PadR PF03551.9 AIF85369.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.1 AIF85369.1 - 0.0052 16.7 0.1 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 AIF85369.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 MarR family TrmB PF01978.14 AIF85369.1 - 0.029 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF3051 PF11252.3 AIF85369.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) PepSY PF03413.14 AIF85370.1 - 0.022 15.4 0.1 0.042 14.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DEK_C PF08766.6 AIF85372.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 DEK C terminal domain Ammonium_transp PF00909.16 AIF85373.1 - 2.4e-116 388.4 34.3 3.1e-116 388.1 23.7 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_hydro_57 PF03065.10 AIF85374.1 - 0.074 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 ResIII PF04851.10 AIF85375.1 - 8.2e-25 87.6 0.1 2.3e-23 82.9 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AIF85375.1 - 8.7e-14 51.1 0.0 2.3e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AIF85375.1 - 1.1e-10 41.2 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 AIF85375.1 - 0.00012 21.0 0.0 0.00047 19.0 0.0 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 AIF85375.1 - 0.098 12.8 0.0 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF790 PF05626.6 AIF85376.1 - 2.2e-91 306.2 0.0 1.6e-90 303.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF790) Phage_integrase PF00589.17 AIF85377.1 - 8.9e-17 61.2 0.1 1.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 AIF85377.1 - 0.0015 18.6 0.1 0.0098 16.0 0.0 2.5 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain OrfB_Zn_ribbon PF07282.6 AIF85377.1 - 0.0057 16.2 1.2 0.013 15.1 0.1 2.1 2 0 0 2 2 2 1 Putative transposase DNA-binding domain DZR PF12773.2 AIF85377.1 - 0.0063 16.3 2.4 0.091 12.5 0.4 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AIF85377.1 - 0.013 14.6 1.3 0.028 13.6 0.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Phage_int_SAM_4 PF13495.1 AIF85377.1 - 0.022 15.0 1.1 4 7.8 0.0 3.2 2 2 3 5 5 5 0 Phage integrase, N-terminal SAM-like domain zf-tcix PF14952.1 AIF85377.1 - 0.058 12.7 8.4 0.12 11.7 0.8 2.5 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zinc_ribbon_2 PF13240.1 AIF85377.1 - 0.087 12.3 2.9 0.2 11.2 2.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AIF85377.1 - 0.32 10.3 2.9 2.5 7.5 2.0 2.3 1 1 0 1 1 1 0 TFIIB zinc-binding YhfH PF14149.1 AIF85377.1 - 0.42 10.4 0.1 0.42 10.4 0.0 2.9 3 0 0 3 3 3 0 YhfH-like protein APG17 PF04108.7 AIF85378.1 - 0.067 11.9 0.4 0.062 12.0 0.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 ParG PF09274.5 AIF85379.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 ParG AAA_18 PF13238.1 AIF85380.1 - 4.9e-13 49.5 0.0 7.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AIF85380.1 - 1.2e-08 35.8 0.1 2.2e-08 34.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AIF85380.1 - 6.1e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AIF85380.1 - 1.3e-05 25.3 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AIF85380.1 - 0.00099 19.1 0.0 0.0014 18.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin2 PF13189.1 AIF85380.1 - 0.0024 17.8 0.0 0.93 9.3 0.0 2.1 2 0 0 2 2 2 2 Cytidylate kinase-like family CoaE PF01121.15 AIF85380.1 - 0.0044 16.4 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase Torsin PF06309.6 AIF85380.1 - 0.0061 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Torsin ADK PF00406.17 AIF85380.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase NB-ARC PF00931.17 AIF85380.1 - 0.017 14.0 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.17 AIF85380.1 - 0.024 14.4 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 AIF85380.1 - 0.029 14.0 0.0 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 NTPase MobB PF03205.9 AIF85380.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 AIF85380.1 - 0.034 13.2 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 AIF85380.1 - 0.035 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.15 AIF85380.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 AIF85380.1 - 0.079 11.9 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 AIF85380.1 - 0.093 12.2 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ASCH PF04266.9 AIF85381.1 - 2.5e-05 24.5 0.0 4.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ASCH domain N6-adenineMlase PF10237.4 AIF85382.1 - 0.0014 18.3 0.0 0.0048 16.5 0.0 1.8 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase Radical_SAM PF04055.16 AIF85383.1 - 1.8e-05 24.9 0.0 4.6e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 AIF85383.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.1 AIF85383.1 - 0.04 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF4186 PF13811.1 AIF85384.1 - 4.1e-27 94.0 0.0 7.3e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4186) GDNF PF02351.11 AIF85384.1 - 0.067 13.7 2.7 2.7 8.5 0.2 2.2 2 0 0 2 2 2 0 GDNF/GAS1 domain Cript PF10235.4 AIF85384.1 - 0.11 12.9 1.7 0.49 10.7 0.0 2.6 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT HTH_3 PF01381.17 AIF85385.1 - 1.6e-09 37.4 0.6 6.1e-09 35.6 0.6 2.0 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.2 AIF85385.1 - 1e-07 31.8 0.2 3.5e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain DUF955 PF06114.8 AIF85385.1 - 3e-07 30.1 0.0 1e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF955) HTH_31 PF13560.1 AIF85385.1 - 1.9e-06 27.9 0.2 5.6e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 AIF85385.1 - 0.00021 20.8 1.2 0.00045 19.7 0.3 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.1 AIF85385.1 - 0.00051 19.7 0.5 0.0025 17.6 0.5 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 AIF85385.1 - 0.00075 19.0 0.1 0.0026 17.3 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain Pou PF00157.12 AIF85385.1 - 0.0044 16.6 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Phage_terminase PF10668.4 AIF85385.1 - 0.025 14.3 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 Phage terminase small subunit Peptidase_U49 PF10463.4 AIF85385.1 - 0.027 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase U49 HTH_26 PF13443.1 AIF85385.1 - 0.03 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.1 AIF85385.1 - 0.045 13.7 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 AIF85385.1 - 0.093 12.6 0.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Transposase PepSY PF03413.14 AIF85387.1 - 0.0013 19.3 1.9 0.0027 18.2 1.3 1.8 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain CelD_N PF02927.9 AIF85388.1 - 0.07 13.3 0.2 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 N-terminal ig-like domain of cellulase BNR_2 PF13088.1 AIF85391.1 - 1e-09 38.1 11.8 9.2e-05 21.8 0.3 3.8 2 1 2 4 4 4 2 BNR repeat-like domain BNR PF02012.15 AIF85391.1 - 0.00015 21.1 31.0 0.24 11.3 0.4 6.8 6 0 0 6 6 6 4 BNR/Asp-box repeat Reprolysin_3 PF13582.1 AIF85394.1 - 0.0036 17.8 0.4 0.0036 17.8 0.3 2.1 1 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 AIF85394.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) CarboxypepD_reg PF13620.1 AIF85394.1 - 0.16 12.0 6.8 0.3 11.1 4.7 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Peptidase_A24 PF01478.13 AIF85396.1 - 0.95 9.6 12.4 4 7.6 8.6 2.0 1 1 0 1 1 1 0 Type IV leader peptidase family DUF1814 PF08843.6 AIF85398.1 - 9.9e-29 100.7 1.6 1.3e-28 100.4 1.1 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF4095 PF13338.1 AIF85399.1 - 8.6e-22 77.5 0.0 1.7e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4095) DUF91 PF01939.11 AIF85399.1 - 1.4e-06 27.6 1.7 1.6e-06 27.4 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF91 TrmB PF01978.14 AIF85399.1 - 5.3e-05 22.8 0.1 0.0016 18.0 0.1 2.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB CPSase_L_D2 PF02786.12 AIF85399.1 - 0.019 14.2 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TF_Zn_Ribbon PF08271.7 AIF85401.1 - 0.00047 19.4 0.2 0.00083 18.6 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 AIF85401.1 - 0.034 13.6 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-Mss51 PF13824.1 AIF85401.1 - 0.4 10.5 2.8 1.4 8.7 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 ParBc PF02195.13 AIF85402.1 - 6.3e-08 32.6 0.7 1.6e-07 31.2 0.5 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain DUF1456 PF07308.8 AIF85402.1 - 0.06 13.3 0.0 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) FcoT PF10862.3 AIF85403.1 - 0.094 12.2 0.2 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain PT-VENN PF04829.8 AIF85406.1 - 0.95 9.0 0.1 0.95 9.0 0.0 2.3 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif PrgI PF12666.2 AIF85407.1 - 0.00015 21.8 1.1 0.00042 20.3 0.8 1.7 1 1 0 1 1 1 1 PrgI family protein FUSC_2 PF13515.1 AIF85407.1 - 0.013 15.4 1.0 0.016 15.1 0.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein-like CAMSAP_CH PF11971.3 AIF85407.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain AAA_10 PF12846.2 AIF85408.1 - 3.1e-35 122.1 0.1 1e-24 87.5 0.0 2.2 1 1 1 2 2 2 2 AAA-like domain DUF87 PF01935.12 AIF85408.1 - 1.9e-09 37.6 0.0 4.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 AIF85408.1 - 0.00019 21.0 0.0 0.0048 16.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 AIF85408.1 - 0.0049 16.1 0.0 0.016 14.4 0.0 1.8 2 0 0 2 2 2 1 Poxvirus A32 protein ABC_tran PF00005.22 AIF85408.1 - 0.019 15.2 0.0 6.6 7.0 0.0 2.6 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 AIF85408.1 - 0.044 13.9 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase GerE PF00196.14 AIF85408.1 - 0.23 10.7 1.1 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family CarboxypepD_reg PF13620.1 AIF85410.1 - 4.7e-07 29.7 2.2 8.6e-07 28.9 1.5 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 AIF85410.1 - 0.00013 21.9 0.1 0.00021 21.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Peptidase_M54 PF07998.6 AIF85410.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF4198 PF10670.4 AIF85410.1 - 0.025 14.5 0.1 0.086 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) HxlR PF01638.12 AIF85412.1 - 0.00056 19.4 0.3 0.00099 18.6 0.2 1.5 1 1 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.17 AIF85412.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 MarR family Penicillinase_R PF03965.11 AIF85412.1 - 0.022 14.8 0.1 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor MarR_2 PF12802.2 AIF85412.1 - 0.048 13.3 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 MarR family Nic96 PF04097.9 AIF85413.1 - 0.01 13.9 0.0 0.016 13.3 0.0 1.2 1 0 0 1 1 1 0 Nup93/Nic96 DUF1778 PF08681.6 AIF85413.1 - 0.035 13.9 0.1 0.22 11.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1778) DUF2790 PF10976.3 AIF85413.1 - 0.095 12.5 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) HicB PF05534.7 AIF85417.1 - 0.0004 19.9 0.0 0.00075 19.0 0.0 1.5 1 0 0 1 1 1 1 HicB family RHH_1 PF01402.16 AIF85417.1 - 0.016 15.1 1.9 0.069 13.0 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family TRCF PF03461.10 AIF85418.1 - 0.0032 17.3 0.2 0.0042 17.0 0.1 1.4 1 1 0 1 1 1 1 TRCF domain DUF4164 PF13747.1 AIF85418.1 - 0.054 13.6 0.4 0.1 12.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) HTH_30 PF13556.1 AIF85418.1 - 0.09 12.3 0.5 0.21 11.1 0.1 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Mad3_BUB1_I PF08311.7 AIF85418.1 - 0.094 12.5 0.1 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 C1_1 PF00130.17 AIF85419.1 - 0.014 15.0 7.7 0.89 9.3 3.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.9 AIF85419.1 - 0.076 12.6 5.2 0.27 10.9 0.0 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid DZR PF12773.2 AIF85419.1 - 0.12 12.2 7.8 1.5 8.7 2.9 2.3 3 0 0 3 3 3 0 Double zinc ribbon GCS PF03074.11 AIF85419.1 - 0.14 11.1 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase OrfB_Zn_ribbon PF07282.6 AIF85419.1 - 4 7.1 8.0 3.2 7.4 2.6 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Sar8_2 PF03058.9 AIF85422.1 - 0.58 10.5 4.4 0.68 10.2 3.1 1.1 1 0 0 1 1 1 0 Sar8.2 family DUF4366 PF14283.1 AIF85423.1 - 0.0044 16.4 0.1 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF2834 PF11196.3 AIF85423.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) AAA_10 PF12846.2 AIF85426.1 - 1.4e-06 27.9 0.0 6e-06 25.9 0.0 1.8 1 1 1 2 2 2 1 AAA-like domain AAA_14 PF13173.1 AIF85426.1 - 0.084 12.7 0.0 1.7 8.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain zf-C2H2_2 PF12756.2 AIF85427.1 - 0.00062 19.8 0.0 0.00087 19.3 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AIF85427.1 - 0.00085 19.5 0.2 0.0013 18.9 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF85427.1 - 0.026 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 AIF85427.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.6 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 AIF85427.1 - 0.05 13.5 0.2 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AIF85427.1 - 0.18 12.1 0.3 0.18 12.1 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double domain Chlorosome_CsmC PF11098.3 AIF85429.1 - 0.051 13.2 3.8 0.16 11.6 0.8 2.2 2 0 0 2 2 2 0 Chlorosome envelope protein C Gate PF07670.9 AIF85429.1 - 0.088 12.7 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleoside recognition Coiled-coil_56 PF09813.4 AIF85429.1 - 0.14 12.1 0.3 0.29 11.1 0.1 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Saf-Nte_pilin PF09460.5 AIF85430.1 - 0.085 12.6 0.3 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Saf-pilin pilus formation protein F5_F8_type_C PF00754.20 AIF85432.1 - 7.1e-17 61.4 0.4 1.4e-16 60.4 0.3 1.5 1 0 0 1 1 1 1 F5/8 type C domain A2M_N_2 PF07703.9 AIF85432.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region bZIP_2 PF07716.10 AIF85433.1 - 0.03 14.1 0.2 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 AIF85433.1 - 0.048 13.6 0.3 0.048 13.6 0.2 1.1 1 0 0 1 1 1 0 bZIP transcription factor MerR-DNA-bind PF09278.6 AIF85433.1 - 0.65 10.4 3.4 1 9.8 2.4 1.4 1 1 0 1 1 1 0 MerR, DNA binding DUF2524 PF10732.4 AIF85436.1 - 1.7e-05 24.8 0.8 2.8e-05 24.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2524) CytochromB561_N PF09786.4 AIF85436.1 - 0.019 13.4 1.6 0.033 12.6 1.1 1.5 1 1 0 1 1 1 0 Cytochrome B561, N terminal ETRAMP PF09716.5 AIF85436.1 - 2.5 8.1 6.3 0.56 10.1 0.8 2.3 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Hemerythrin PF01814.18 AIF85438.1 - 2.7e-08 34.0 10.5 9.6e-08 32.2 7.3 1.9 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Arfaptin PF06456.8 AIF85438.1 - 0.046 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Arfaptin-like domain RHH_2 PF03693.9 AIF85438.1 - 0.062 13.4 0.6 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0156) HALZ PF02183.13 AIF85438.1 - 4.2 7.1 6.8 0.88 9.3 0.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fer4 PF00037.22 AIF85439.1 - 2.7e-11 42.5 10.2 7.2e-06 25.3 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AIF85439.1 - 3e-11 43.5 26.4 2.9e-07 30.7 6.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF85439.1 - 2.4e-09 36.8 2.3 0.00017 21.2 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIF85439.1 - 5.5e-09 35.5 10.5 2.2e-05 24.0 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AIF85439.1 - 6.4e-09 35.9 5.6 1.9e-08 34.4 3.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF85439.1 - 5e-08 32.8 22.3 1.3e-05 25.0 4.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 AIF85439.1 - 1.5e-07 30.9 8.7 0.00099 18.9 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 AIF85439.1 - 6.9e-07 29.9 4.9 0.00013 22.6 0.5 2.5 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 AIF85439.1 - 4.6e-06 26.3 7.4 0.00024 20.8 5.2 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AIF85439.1 - 8.6e-06 26.0 7.8 0.00021 21.6 4.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIF85439.1 - 1.5e-05 24.9 7.6 0.024 14.9 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AIF85439.1 - 1.9e-05 24.9 5.0 0.00046 20.4 4.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 AIF85439.1 - 2.3e-05 24.8 6.9 0.013 16.0 0.1 2.9 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 AIF85439.1 - 0.0013 19.1 14.1 0.14 12.7 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AIF85439.1 - 0.0054 17.0 13.8 0.047 14.0 0.2 3.0 3 1 0 3 3 3 2 4Fe-4S single cluster domain Fer4_11 PF13247.1 AIF85439.1 - 0.0092 15.8 0.8 1.9 8.4 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Hemerythrin PF01814.18 AIF85441.1 - 8.3e-11 42.1 11.0 8.2e-10 38.9 4.5 1.8 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Cas_Csa5 PF09702.5 AIF85441.1 - 0.02 14.9 0.4 0.029 14.4 0.3 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) DUF465 PF04325.8 AIF85441.1 - 0.029 14.0 0.3 0.066 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DCP2 PF05026.8 AIF85441.1 - 0.086 12.7 0.5 0.15 12.0 0.4 1.5 1 1 0 1 1 1 0 Dcp2, box A domain Glu_syn_central PF04898.9 AIF85441.1 - 0.13 11.5 1.8 0.14 11.4 1.2 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain DUF488 PF04343.8 AIF85442.1 - 3.1e-26 92.1 0.2 3.8e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF488 UvdE PF03851.9 AIF85444.1 - 0.0079 15.2 0.0 0.0082 15.2 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE Lge1 PF11488.3 AIF85446.1 - 0.034 14.3 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF4045 PF13254.1 AIF85447.1 - 0.024 13.9 6.1 0.028 13.7 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HEAT_2 PF13646.1 AIF85447.1 - 0.024 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 HEAT repeats Cid2 PF09774.4 AIF85447.1 - 1.1 9.3 4.8 2.4 8.2 2.8 1.8 1 1 0 1 1 1 0 Caffeine-induced death protein 2 TrmB PF01978.14 AIF85448.1 - 2.8e-07 30.1 1.4 0.11 12.1 0.0 3.7 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AIF85448.1 - 7e-06 25.7 0.0 0.96 9.2 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_11 PF08279.7 AIF85448.1 - 6.5e-05 22.5 0.7 0.23 11.1 0.0 2.8 2 0 0 2 2 2 2 HTH domain HTH_27 PF13463.1 AIF85448.1 - 0.00012 22.3 2.3 1.2 9.5 0.0 4.3 4 0 0 4 4 4 1 Winged helix DNA-binding domain Trp_repressor PF01371.14 AIF85448.1 - 0.00064 19.5 0.1 0.13 12.2 0.0 2.8 2 0 0 2 2 2 1 Trp repressor protein DUF4423 PF14394.1 AIF85448.1 - 0.0014 18.1 0.7 2.2 7.7 0.0 3.4 2 1 0 3 3 3 1 Domain of unknown function (DUF4423) Penicillinase_R PF03965.11 AIF85448.1 - 0.0017 18.4 0.7 0.062 13.3 0.1 2.9 2 1 0 2 2 2 1 Penicillinase repressor HTH_36 PF13730.1 AIF85448.1 - 0.0023 18.0 1.0 6.5 6.9 0.0 3.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 AIF85448.1 - 0.0026 17.1 0.6 0.32 10.3 0.0 3.5 4 1 0 4 4 4 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 AIF85448.1 - 0.0028 17.1 0.2 0.012 15.1 0.1 2.1 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain PaaX PF07848.7 AIF85448.1 - 0.0058 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 PaaX-like protein Cullin_Nedd8 PF10557.4 AIF85448.1 - 0.011 15.5 1.2 1.5 8.7 0.1 3.3 3 0 0 3 3 3 0 Cullin protein neddylation domain MarR_2 PF12802.2 AIF85448.1 - 0.011 15.3 0.1 1.6 8.4 0.0 3.4 3 0 0 3 3 3 0 MarR family HTH_12 PF08461.5 AIF85448.1 - 0.024 14.3 0.9 0.08 12.6 0.4 2.1 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain MarR PF01047.17 AIF85448.1 - 0.11 12.1 1.3 3.3 7.4 0.1 3.2 3 0 0 3 3 3 0 MarR family YjcQ PF09639.5 AIF85448.1 - 0.14 12.2 1.8 15 5.7 0.0 3.5 4 0 0 4 4 3 0 YjcQ protein PD40 PF07676.7 AIF85450.1 - 5.9e-08 32.2 14.9 0.035 13.7 0.2 5.6 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 AIF85450.1 - 0.00014 21.3 0.0 0.0014 18.0 0.0 2.5 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain DPPIV_N PF00930.16 AIF85450.1 - 0.00029 19.5 0.4 0.91 8.0 0.0 3.2 2 1 0 3 3 3 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.27 AIF85450.1 - 0.0069 16.2 1.2 0.62 10.0 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat CarboxypepD_reg PF13620.1 AIF85455.1 - 2.4e-16 59.5 17.0 6.5e-07 29.3 0.3 8.0 8 1 1 9 9 9 4 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 AIF85455.1 - 5e-08 32.8 0.2 0.0079 16.2 0.0 5.0 4 0 0 4 4 4 2 Domain of unknown function (DUF4480) Big_1 PF02369.11 AIF85455.1 - 0.006 16.4 16.8 0.0069 16.2 0.0 5.8 7 0 0 7 7 7 2 Bacterial Ig-like domain (group 1) Cna_B PF05738.8 AIF85455.1 - 0.21 11.3 9.4 20 5.0 0.0 5.5 6 0 0 6 6 6 0 Cna protein B-type domain PAP2_C PF14360.1 AIF85458.1 - 0.011 15.9 2.1 0.015 15.5 1.5 1.2 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Claudin_2 PF13903.1 AIF85458.1 - 0.023 14.3 2.9 0.026 14.2 2.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction GerA PF03323.8 AIF85458.1 - 0.042 12.0 0.5 0.048 11.7 0.3 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein PhaG_MnhG_YufB PF03334.9 AIF85458.1 - 0.093 12.7 4.4 0.13 12.3 2.7 1.4 1 1 0 1 1 1 0 Na+/H+ antiporter subunit DUF3953 PF13129.1 AIF85458.1 - 0.11 12.1 0.4 0.11 12.1 0.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) DUF3796 PF12676.2 AIF85458.1 - 0.13 12.4 1.5 0.16 12.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF2721 PF11026.3 AIF85458.1 - 0.2 11.2 4.8 0.084 12.5 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) PrgI PF12666.2 AIF85458.1 - 0.26 11.4 3.0 0.35 11.0 2.1 1.2 1 0 0 1 1 1 0 PrgI family protein DUF202 PF02656.10 AIF85458.1 - 1 9.6 5.4 2.1 8.6 3.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) CcoS PF03597.10 AIF85458.1 - 5.5 6.5 10.6 1.5 8.3 1.2 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF4149 PF13664.1 AIF85459.1 - 0.0054 16.7 1.6 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) TPT PF03151.11 AIF85459.1 - 0.01 15.4 3.3 0.016 14.8 2.2 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family Arteri_Gl PF00951.13 AIF85459.1 - 0.21 11.1 3.7 0.13 11.8 1.0 1.7 1 1 0 1 1 1 0 Arterivirus GL envelope glycoprotein Abi PF02517.11 AIF85459.1 - 1.3 9.2 6.4 0.37 10.9 2.4 1.6 2 0 0 2 2 2 0 CAAX protease self-immunity PadR PF03551.9 AIF85461.1 - 0.057 13.1 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RHH_1 PF01402.16 AIF85463.1 - 0.032 14.1 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family BRK PF07533.11 AIF85463.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 BRK domain Hemerythrin PF01814.18 AIF85465.1 - 0.00061 19.9 0.3 0.00061 19.9 0.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TOM_sub5 PF15178.1 AIF85465.1 - 0.023 14.3 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM5 homolog F-112 PF09645.5 AIF85465.1 - 0.091 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 F-112 protein CytadhesinP1 PF12378.3 AIF85465.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein DivIC PF04977.10 AIF85466.1 - 0.016 14.6 0.1 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Pox_A_type_inc PF04508.7 AIF85466.1 - 0.044 13.5 3.1 0.17 11.7 0.3 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DMPK_coil PF08826.5 AIF85466.1 - 0.086 12.7 0.4 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like bZIP_1 PF00170.16 AIF85466.1 - 0.61 10.0 2.8 0.59 10.1 0.7 1.8 2 1 0 2 2 2 0 bZIP transcription factor Aldedh PF00171.17 AIF85467.1 - 2.6e-152 507.3 2.3 2.9e-152 507.2 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AIF85467.1 - 0.0017 17.1 0.7 0.028 13.1 0.0 2.1 1 1 1 2 2 2 1 Acyl-CoA reductase (LuxC) UPF0231 PF06062.6 AIF85467.1 - 0.12 12.2 0.3 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) RNA_polI_A14 PF08203.6 AIF85467.1 - 0.16 12.2 0.4 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 ADH_N PF08240.7 AIF85468.1 - 8.5e-34 115.5 0.3 1.4e-33 114.9 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AIF85468.1 - 1.8e-31 108.3 0.6 1.1e-30 105.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AIF85468.1 - 1.7e-12 48.3 0.6 3.3e-12 47.4 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AIF85468.1 - 8.4e-05 22.2 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Hydant_A_N PF05378.8 AIF85468.1 - 0.0017 17.8 0.1 0.004 16.6 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Met_10 PF02475.11 AIF85468.1 - 0.014 14.9 0.1 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DapB_N PF01113.15 AIF85468.1 - 0.034 14.0 1.7 0.072 13.0 1.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_11 PF08241.7 AIF85468.1 - 0.034 14.6 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 AIF85468.1 - 0.041 13.8 0.2 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain PrmA PF06325.8 AIF85468.1 - 0.048 12.7 0.6 0.07 12.2 0.4 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AIF85468.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 AIF85468.1 - 0.12 11.9 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HhH-GPD PF00730.20 AIF85469.1 - 1.4e-17 63.8 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.1 AIF85469.1 - 0.011 15.9 0.0 8.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain OGG_N PF07934.7 AIF85469.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain DUF488 PF04343.8 AIF85470.1 - 6.3e-30 104.0 0.0 8e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF488 DBD_Tnp_Mut PF03108.10 AIF85470.1 - 0.019 14.5 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 MuDR family transposase Fer4_7 PF12838.2 AIF85471.1 - 8.7e-12 45.2 26.6 6e-07 29.7 6.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.22 AIF85471.1 - 1.8e-11 43.1 10.4 5.1e-06 25.8 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 AIF85471.1 - 2.1e-09 36.8 10.3 2e-05 24.2 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AIF85471.1 - 2.4e-09 36.8 3.0 0.00015 21.4 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF85471.1 - 3.8e-09 36.4 0.5 0.0013 18.7 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 AIF85471.1 - 2.8e-08 33.8 7.4 4.3e-07 30.0 5.1 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AIF85471.1 - 7e-08 32.2 1.7 0.00039 20.2 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 AIF85471.1 - 8.8e-08 32.7 3.1 8.4e-05 23.2 0.6 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.2 AIF85471.1 - 2.3e-07 30.3 8.7 0.00087 19.0 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 AIF85471.1 - 3.9e-06 27.2 8.7 7.5e-05 23.0 4.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIF85471.1 - 9.3e-06 25.5 7.6 0.021 15.1 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AIF85471.1 - 1.4e-05 25.5 6.4 0.016 15.7 0.2 2.9 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_17 PF13534.1 AIF85471.1 - 2.5e-05 24.5 4.9 0.00065 19.9 4.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.2 AIF85471.1 - 0.00074 19.9 14.3 0.089 13.4 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AIF85471.1 - 0.0028 18.0 12.4 0.058 13.7 0.2 2.8 3 1 0 3 3 3 2 4Fe-4S single cluster domain Fer4_11 PF13247.1 AIF85471.1 - 0.017 14.9 0.8 1.5 8.7 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Patatin PF01734.17 AIF85472.1 - 3.9e-18 66.1 0.0 1.6e-17 64.1 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3734 PF12536.3 AIF85472.1 - 0.0024 17.9 0.4 0.0062 16.6 0.2 1.8 1 1 0 1 1 1 1 Patatin phospholipase NAD_binding_1 PF00175.16 AIF85473.1 - 4.9e-20 72.1 0.0 8.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Rieske PF00355.21 AIF85473.1 - 2.5e-12 46.1 0.0 4.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_6 PF00970.19 AIF85473.1 - 2.5e-09 37.1 0.0 4.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AIF85473.1 - 0.001 18.9 0.0 0.062 13.2 0.0 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF3688 PF12461.3 AIF85473.1 - 0.035 14.5 0.5 0.073 13.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) CBS PF00571.23 AIF85475.1 - 6e-31 105.9 0.9 1.9e-14 53.1 0.1 2.1 2 0 0 2 2 2 2 CBS domain PigN PF04987.9 AIF85476.1 - 0.009 14.6 0.1 0.0093 14.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) HxlR PF01638.12 AIF85477.1 - 2.5e-21 75.0 0.0 3.5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.17 AIF85477.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_12 PF08461.5 AIF85477.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_24 PF13412.1 AIF85477.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AmoC PF04896.7 AIF85479.1 - 5.8e-16 58.2 4.3 7e-16 58.0 3.0 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C NMN_transporter PF04973.7 AIF85479.1 - 0.75 9.2 8.1 0.6 9.5 4.1 1.8 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter Fer4_7 PF12838.2 AIF85480.1 - 1.2e-10 41.5 25.9 3.1e-06 27.4 6.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.22 AIF85480.1 - 3.3e-10 39.1 11.6 3.1e-06 26.5 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AIF85480.1 - 1.6e-08 34.6 5.3 4.6e-08 33.1 3.6 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AIF85480.1 - 3.4e-08 33.3 22.7 1.7e-05 24.7 5.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.1 AIF85480.1 - 3.7e-08 33.0 19.2 3.5e-06 26.7 6.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AIF85480.1 - 4.3e-08 32.6 12.4 0.00064 19.4 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AIF85480.1 - 2.6e-07 31.0 3.2 0.0013 19.2 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_2 PF12797.2 AIF85480.1 - 3.1e-07 29.9 10.1 0.0025 17.6 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 AIF85480.1 - 2.3e-06 28.2 5.7 0.0012 19.4 0.8 2.6 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 AIF85480.1 - 2.4e-06 27.3 7.1 9.6e-05 22.1 5.0 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 AIF85480.1 - 1e-05 25.7 11.9 0.00015 22.0 4.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AIF85480.1 - 1.3e-05 25.1 5.9 0.023 14.9 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 AIF85480.1 - 1.7e-05 25.1 7.8 0.00011 22.5 4.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 AIF85480.1 - 7.1e-05 23.1 8.2 0.0097 16.2 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_11 PF13247.1 AIF85480.1 - 0.0043 16.9 1.1 2.2 8.2 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 AIF85480.1 - 0.016 15.6 14.8 0.092 13.3 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Abhydrolase_6 PF12697.2 AIF85481.1 - 2.2e-32 112.7 0.0 2.5e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AIF85481.1 - 7.8e-20 71.4 0.0 1.6e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AIF85481.1 - 2.1e-15 56.7 0.0 1.2e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 AIF85481.1 - 3.7e-14 51.8 0.0 4.6e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family DUF1057 PF06342.7 AIF85481.1 - 0.00028 19.7 0.0 0.00048 19.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 AIF85481.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.6 1 1 1 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 AIF85481.1 - 0.0019 17.8 0.0 0.007 15.9 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF3530 PF12048.3 AIF85481.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) UPF0227 PF05728.7 AIF85481.1 - 0.016 14.9 0.0 3.9 7.1 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 AIF85481.1 - 0.018 14.2 0.0 0.12 11.5 0.0 2.3 1 1 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 AIF85481.1 - 0.023 14.2 0.0 0.098 12.2 0.0 1.8 1 1 1 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.3 AIF85481.1 - 0.027 14.3 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 AIF85481.1 - 0.035 13.6 0.0 0.092 12.3 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 AIF85481.1 - 0.039 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Patatin PF01734.17 AIF85481.1 - 0.094 12.6 0.4 4.7 7.0 0.3 2.0 1 1 0 1 1 1 0 Patatin-like phospholipase Usp PF00582.21 AIF85482.1 - 3.3e-19 69.4 2.3 4.3e-19 69.1 1.6 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF3829 PF12889.2 AIF85482.1 - 0.016 14.4 0.2 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF4371 PF14291.1 AIF85482.1 - 0.052 13.0 0.1 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) Fcf1 PF04900.7 AIF85482.1 - 0.082 12.9 0.3 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Fcf1 Na_H_Exchanger PF00999.16 AIF85483.1 - 2.7e-57 194.0 51.6 3.4e-57 193.7 35.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GSDH PF07995.6 AIF85485.1 - 1.3e-71 241.4 0.1 1.5e-58 198.4 0.4 2.1 2 0 0 2 2 2 2 Glucose / Sorbosone dehydrogenase Tachylectin PF14517.1 AIF85485.1 - 0.0075 15.6 0.2 6.3 6.0 0.0 3.4 3 1 1 4 4 4 2 Tachylectin NHL PF01436.16 AIF85485.1 - 0.063 13.2 0.1 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 NHL repeat Reg_prop PF07494.6 AIF85485.1 - 0.11 12.5 0.0 32 5.0 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller FMN_red PF03358.10 AIF85486.1 - 4e-09 36.1 0.0 4.4e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase FMN_red PF03358.10 AIF85487.1 - 1.4e-11 44.1 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Usp PF00582.21 AIF85488.1 - 1.5e-32 112.6 1.4 1.8e-32 112.4 0.9 1.0 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.23 AIF85489.1 - 1e-45 153.2 4.0 2e-13 49.8 0.1 4.2 4 0 0 4 4 4 4 CBS domain SMC_hinge PF06470.8 AIF85489.1 - 0.008 16.1 0.1 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain DUF2577 PF10844.3 AIF85489.1 - 0.019 14.9 0.3 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Na_sulph_symp PF00939.14 AIF85491.1 - 5.7e-59 200.2 29.3 7.1e-59 199.9 20.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 AIF85491.1 - 3.4e-08 32.4 45.9 0.00036 19.2 6.9 3.2 2 1 1 3 3 3 3 Citrate transporter Patatin PF01734.17 AIF85492.1 - 3.9e-21 75.9 0.0 1.4e-20 74.0 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3734 PF12536.3 AIF85492.1 - 0.0007 19.6 1.2 0.0021 18.1 0.8 1.8 1 1 0 1 1 1 1 Patatin phospholipase FUSC-like PF12805.2 AIF85492.1 - 0.017 14.0 0.5 0.076 11.9 0.8 1.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS ATP-cone PF03477.11 AIF85493.1 - 5.8e-14 52.2 0.2 9.2e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 ATP cone domain N-SET PF11764.3 AIF85493.1 - 0.023 14.6 3.9 0.022 14.6 2.5 1.3 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N UPF0086 PF01868.11 AIF85494.1 - 0.0026 17.3 0.2 0.48 10.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function UPF0086 Kelch_2 PF07646.10 AIF85494.1 - 0.0089 15.7 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Metallophos_3 PF14582.1 AIF85494.1 - 0.057 12.5 0.0 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily zf-C2H2 PF00096.21 AIF85495.1 - 0.00018 21.6 0.2 0.00018 21.6 0.1 1.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AIF85495.1 - 0.00032 20.8 0.8 0.00053 20.1 0.6 1.5 1 1 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 AIF85495.1 - 0.00041 20.4 0.5 0.00041 20.4 0.3 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AIF85495.1 - 0.0089 16.1 0.5 0.0094 16.0 0.4 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AIF85495.1 - 0.035 14.2 0.2 0.035 14.2 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 AIF85495.1 - 0.043 14.1 1.6 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 AIF85495.1 - 0.058 13.3 2.5 0.2 11.5 1.7 1.8 1 1 0 1 1 1 0 C2H2-type zinc finger Cytochrome_C7 PF14522.1 AIF85495.1 - 0.13 11.8 0.3 0.17 11.5 0.2 1.3 1 1 0 1 1 1 0 Cytochrome c7 zf-DBF PF07535.7 AIF85495.1 - 0.14 11.8 1.7 0.18 11.4 1.2 1.2 1 0 0 1 1 1 0 DBF zinc finger Copper-bind PF00127.15 AIF85496.1 - 8.4e-13 48.4 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF85496.1 - 5.4e-07 29.4 0.0 1.4e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Cupredoxin-like domain C1-set PF07654.10 AIF85496.1 - 0.005 16.8 0.1 0.0082 16.1 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain DUF3937 PF13073.1 AIF85496.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) Usp PF00582.21 AIF85498.1 - 1.7e-29 102.8 0.1 3.7e-29 101.7 0.1 1.5 1 1 0 1 1 1 1 Universal stress protein family DUF3867 PF12983.2 AIF85498.1 - 0.065 13.1 0.6 0.14 12.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) Macoilin PF09726.4 AIF85500.1 - 0.7 8.0 14.5 0.86 7.8 10.0 1.1 1 0 0 1 1 1 0 Transmembrane protein FcoT PF10862.3 AIF85501.1 - 0.14 11.6 0.2 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 FcoT-like thioesterase domain Asn_synthase PF00733.16 AIF85502.1 - 1.6e-54 185.0 0.3 5.8e-54 183.2 0.0 1.9 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 AIF85502.1 - 5.8e-31 106.8 0.2 1.5e-28 99.0 0.3 2.8 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AIF85502.1 - 6.7e-27 94.0 0.1 1.4e-24 86.5 0.2 2.6 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AIF85502.1 - 2e-15 56.3 0.2 2.5e-09 36.3 0.0 2.9 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 AIF85502.1 - 3.6e-05 22.5 0.0 6.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HAUS-augmin3 PF14932.1 AIF85502.1 - 0.00054 19.2 5.7 0.00093 18.4 3.9 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 QueC PF06508.8 AIF85502.1 - 0.0069 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 AIF85502.1 - 0.015 15.1 0.2 0.072 12.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family NAD_synthase PF02540.12 AIF85502.1 - 0.026 13.4 1.1 0.037 12.9 0.0 1.8 2 0 0 2 2 2 0 NAD synthase TMC PF07810.8 AIF85503.1 - 0.025 14.9 0.1 0.026 14.9 0.1 1.1 1 0 0 1 1 1 0 TMC domain MS_channel PF00924.13 AIF85506.1 - 4.6e-48 163.2 0.2 4.6e-48 163.2 0.2 1.4 2 0 0 2 2 2 1 Mechanosensitive ion channel FtsX PF02687.16 AIF85506.1 - 0.91 9.2 11.3 3.6 7.3 1.1 2.3 1 1 0 2 2 2 0 FtsX-like permease family DUF1326 PF07040.6 AIF85507.1 - 9.5e-54 181.9 0.0 1.1e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1326) DUF95 PF01944.12 AIF85508.1 - 0.042 13.4 0.1 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF95 TrkH PF02386.11 AIF85509.1 - 2.5e-33 115.1 33.6 8.7e-32 110.0 16.7 2.7 2 2 0 2 2 2 2 Cation transport protein CBS PF00571.23 AIF85509.1 - 1.6e-17 63.0 1.9 3.3e-09 36.3 0.2 2.4 2 0 0 2 2 2 2 CBS domain DUF4367 PF14285.1 AIF85509.1 - 1.1 8.5 4.0 1.4 8.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4367) Band_7 PF01145.20 AIF85510.1 - 1.2e-28 100.1 9.2 1.9e-28 99.5 6.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family LMBR1 PF04791.11 AIF85510.1 - 0.19 10.2 3.0 0.29 9.6 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_C6 PF00851.13 AIF85510.1 - 0.5 8.9 4.8 0.7 8.4 3.3 1.1 1 0 0 1 1 1 0 Helper component proteinase Na_H_Exchanger PF00999.16 AIF85512.1 - 3.7e-64 216.6 49.2 4.8e-64 216.2 34.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Neur_chan_memb PF02932.11 AIF85513.1 - 2.4e-07 30.9 3.9 3.4e-07 30.3 2.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 AIF85513.1 - 0.047 12.8 0.0 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel ligand binding domain 60KD_IMP PF02096.15 AIF85513.1 - 0.09 12.4 4.0 0.16 11.6 2.7 1.4 1 1 0 1 1 1 0 60Kd inner membrane protein Usp PF00582.21 AIF85515.1 - 1.4e-06 28.5 0.1 2.2e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Universal stress protein family HTH_45 PF14947.1 AIF85519.1 - 1.6e-18 66.2 0.1 2.1e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AIF85519.1 - 0.012 15.1 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF3116 PF11313.3 AIF85519.1 - 0.04 13.5 0.8 0.53 9.9 0.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3116) DUF3987 PF13148.1 AIF85519.1 - 0.056 12.0 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Usp PF00582.21 AIF85521.1 - 2.5e-33 115.2 0.8 2.8e-33 115.0 0.5 1.0 1 0 0 1 1 1 1 Universal stress protein family DUF4079 PF13301.1 AIF85522.1 - 0.0098 15.9 0.9 0.015 15.3 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DmpG_comm PF07836.6 AIF85522.1 - 0.23 10.8 1.8 1.8 8.0 0.1 2.1 1 1 1 2 2 2 0 DmpG-like communication domain UCR_Fe-S_N PF10399.4 AIF85522.1 - 0.43 9.7 0.1 0.43 9.7 0.1 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF202 PF02656.10 AIF85523.1 - 2.1e-16 59.8 3.7 2.1e-16 59.8 2.6 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF4131 PF13567.1 AIF85523.1 - 0.035 13.5 1.6 0.049 13.0 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF996 PF06195.8 AIF85523.1 - 0.065 13.2 4.8 0.084 12.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF996) YtpI PF14007.1 AIF85523.1 - 0.12 12.3 2.4 0.39 10.6 0.1 2.5 2 1 0 2 2 2 0 YtpI-like protein TctB PF07331.6 AIF85523.1 - 0.49 10.0 6.7 0.13 11.9 0.7 2.3 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4199 PF13858.1 AIF85523.1 - 0.58 10.0 5.9 0.23 11.3 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF3185 PF11381.3 AIF85523.1 - 6.4 6.6 11.4 7.8 6.3 4.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) PepSY PF03413.14 AIF85524.1 - 2.6e-07 31.1 1.4 0.00017 22.1 0.2 2.3 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain PepSY_2 PF13670.1 AIF85524.1 - 0.012 15.5 0.3 2.7 7.9 0.0 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Transposase_31 PF04754.7 AIF85524.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative transposase, YhgA-like DUF4451 PF14616.1 AIF85525.1 - 0.01 15.5 0.5 3.5 7.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Cys_rich_CPCC PF14206.1 AIF85525.1 - 0.82 9.2 4.2 1.7 8.2 0.2 2.3 1 1 1 2 2 2 0 Cysteine-rich CPCC DUF2182 PF09948.4 AIF85527.1 - 1.7e-46 158.5 18.9 7.9e-40 136.8 8.6 2.2 2 0 0 2 2 2 2 Predicted metal-binding integral membrane protein (DUF2182) DUF872 PF05915.7 AIF85527.1 - 2 8.3 7.0 0.25 11.1 0.3 2.7 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF1326 PF07040.6 AIF85528.1 - 2.6e-50 170.7 0.0 3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1326) Methyltransf_31 PF13847.1 AIF85530.1 - 1.4e-22 79.9 0.0 1.5e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AIF85530.1 - 2.4e-21 76.0 0.0 3.9e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AIF85530.1 - 1.8e-16 60.2 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AIF85530.1 - 1.7e-15 57.6 0.0 2.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AIF85530.1 - 5.4e-13 49.1 0.0 9.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AIF85530.1 - 1.2e-11 44.8 0.0 2.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AIF85530.1 - 6.7e-11 41.7 0.0 8.6e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AIF85530.1 - 6.4e-09 35.8 0.2 3.6e-08 33.4 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AIF85530.1 - 1.2e-06 27.9 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 AIF85530.1 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AIF85530.1 - 4e-05 22.8 0.0 5.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 AIF85530.1 - 5.7e-05 22.2 0.0 0.00013 21.1 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 AIF85530.1 - 0.00017 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 AIF85530.1 - 0.00038 19.6 0.0 0.00053 19.2 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 AIF85530.1 - 0.00072 18.9 0.0 0.00088 18.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 AIF85530.1 - 0.0019 16.9 0.0 0.0024 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 AIF85530.1 - 0.0027 17.1 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 AIF85530.1 - 0.0042 16.1 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 AIF85530.1 - 0.0094 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_2 PF00891.13 AIF85530.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_29 PF03141.11 AIF85530.1 - 0.1 10.9 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FmrO PF07091.6 AIF85530.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ycf1 PF05758.7 AIF85531.1 - 0.51 7.9 6.3 0.77 7.3 4.4 1.4 1 1 0 1 1 1 0 Ycf1 Na_H_Exchanger PF00999.16 AIF85533.1 - 1.2e-64 218.2 47.6 1.4e-64 217.9 33.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FecCD PF01032.13 AIF85535.1 - 0.025 13.4 0.1 0.035 12.9 0.1 1.1 1 0 0 1 1 1 0 FecCD transport family MarR_2 PF12802.2 AIF85535.1 - 0.046 13.3 0.2 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 MarR family HicB PF05534.7 AIF85536.1 - 0.043 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 HicB family TetR_C_8 PF14278.1 AIF85536.1 - 0.089 13.1 0.9 0.19 12.1 0.6 1.5 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region Big_3_4 PF13754.1 AIF85537.1 - 0.00022 21.4 1.3 0.00022 21.4 0.9 2.1 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) Gmad2 PF10648.4 AIF85537.1 - 0.017 15.2 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination YPEB PF14620.1 AIF85537.1 - 0.11 11.4 0.1 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation TerC PF03741.11 AIF85538.1 - 5.2e-53 179.2 11.2 1.2e-52 178.0 7.8 1.6 1 0 0 1 1 1 1 Integral membrane protein TerC family PepSY PF03413.14 AIF85539.1 - 4.6e-07 30.3 0.6 9.4e-07 29.3 0.4 1.6 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.1 AIF85539.1 - 0.099 12.5 1.9 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Transposase_31 PF04754.7 AIF85539.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative transposase, YhgA-like Band_7 PF01145.20 AIF85541.1 - 5.2e-17 62.3 19.1 1.3e-16 61.0 13.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF4652 PF15525.1 AIF85541.1 - 0.0073 15.7 1.8 0.015 14.7 1.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4652) Adenylsucc_synt PF00709.16 AIF85541.1 - 0.018 13.7 1.5 0.022 13.4 1.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Band_7_1 PF13421.1 AIF85541.1 - 0.018 14.5 0.5 0.029 13.8 0.4 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family Myco_haema PF05692.7 AIF85541.1 - 0.019 13.6 0.1 0.033 12.8 0.1 1.3 1 1 0 1 1 1 0 Mycoplasma haemagglutinin Peptidase_C6 PF00851.13 AIF85541.1 - 0.46 9.0 3.9 0.58 8.7 2.7 1.1 1 0 0 1 1 1 0 Helper component proteinase Na_sulph_symp PF00939.14 AIF85542.1 - 4.3e-75 253.3 31.9 5.8e-75 252.9 22.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 AIF85542.1 - 8.3e-23 80.5 42.6 1.9e-15 56.3 11.4 2.5 2 1 0 2 2 2 2 Citrate transporter Wzy_C PF04932.10 AIF85542.1 - 0.00024 20.9 1.3 0.00024 20.9 0.9 2.9 3 0 0 3 3 3 1 O-Antigen ligase Usp PF00582.21 AIF85543.1 - 2e-18 66.9 0.3 2.3e-18 66.7 0.2 1.0 1 0 0 1 1 1 1 Universal stress protein family Band_7 PF01145.20 AIF85544.1 - 4.2e-32 111.4 1.2 4.2e-32 111.4 0.2 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 AIF85544.1 - 4e-05 23.2 0.0 8.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family NfeD PF01957.13 AIF85545.1 - 3.1e-22 79.2 2.1 3.1e-22 79.2 1.5 2.0 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding CLP_protease PF00574.18 AIF85545.1 - 2.5e-05 24.0 0.6 0.00012 21.8 0.2 2.1 2 0 0 2 2 2 1 Clp protease SDH_sah PF01972.11 AIF85545.1 - 0.0027 16.5 0.3 0.0043 15.8 0.2 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Copper-bind PF00127.15 AIF85548.1 - 0.055 13.7 0.3 0.89 9.8 0.1 2.7 2 1 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Usp PF00582.21 AIF85549.1 - 8.5e-09 35.7 0.1 9.1e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family UPF0060 PF02694.10 AIF85550.1 - 5.3e-16 58.5 3.9 6e-16 58.3 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Lactonase PF10282.4 AIF85551.1 - 1.7e-07 30.7 0.3 0.2 10.7 0.0 4.1 2 2 2 4 4 4 3 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.15 AIF85551.1 - 0.0013 18.6 1.9 29 4.7 0.1 4.4 2 1 2 4 4 4 1 Arylesterase Glyco_hydro_2_N PF02837.13 AIF85551.1 - 0.01 15.4 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain FlaG PF03646.10 AIF85551.1 - 0.085 13.0 4.1 39 4.4 0.0 4.0 4 0 0 4 4 4 0 FlaG protein Copper-bind PF00127.15 AIF85553.1 - 3.5e-09 36.7 0.0 5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF85553.1 - 8.5e-06 25.6 0.1 2e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Cupredoxin-like domain Aminotran_1_2 PF00155.16 AIF85555.1 - 8.1e-34 117.1 0.0 1.5e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Copper-bind PF00127.15 AIF85555.1 - 0.0036 17.5 0.0 0.017 15.3 0.0 2.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF85555.1 - 0.012 15.5 0.1 0.078 12.8 0.0 2.3 2 0 0 2 2 2 0 Cupredoxin-like domain DUF202 PF02656.10 AIF85556.1 - 5.3e-12 45.7 3.6 3.2e-11 43.2 2.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) PepSY_TM_1 PF13172.1 AIF85559.1 - 0.27 11.0 1.8 0.31 10.8 0.6 1.6 1 1 0 1 1 1 0 PepSY-associated TM helix PDZ_2 PF13180.1 AIF85560.1 - 0.034 14.0 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 PDZ domain FTO_CTD PF12934.2 AIF85561.1 - 0.0039 16.7 1.6 0.014 14.9 0.1 2.4 2 1 0 2 2 2 1 FTO C-terminal domain MCM_N PF14551.1 AIF85561.1 - 0.25 11.8 2.5 0.62 10.5 0.8 2.3 1 1 1 2 2 2 0 MCM N-terminal domain DUF3610 PF12272.3 AIF85561.1 - 0.27 10.8 2.4 2.9 7.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3610) Copper-bind PF00127.15 AIF85562.1 - 2.3e-07 30.9 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AIF85562.1 - 1.4e-06 28.1 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain PepSY PF03413.14 AIF85562.1 - 0.00015 22.3 0.1 0.0031 18.1 0.1 2.6 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain FtsQ PF03799.10 AIF85562.1 - 0.15 12.2 0.0 1.5 9.0 0.0 2.4 2 1 1 3 3 3 0 Cell division protein FtsQ Inositol_P PF00459.20 AIF85563.1 - 8.3e-30 103.9 0.3 9.8e-30 103.7 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 AIF85563.1 - 5e-05 22.2 0.0 0.00029 19.8 0.0 1.9 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase FBPase_glpX PF03320.8 AIF85563.1 - 0.027 13.1 0.1 0.051 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded HTH_24 PF13412.1 AIF85564.1 - 8.4e-22 76.3 3.6 1.6e-10 40.2 0.1 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AIF85564.1 - 3e-21 74.6 3.6 1.3e-09 37.3 0.0 3.0 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain MarR_2 PF12802.2 AIF85564.1 - 2e-09 36.9 0.3 4.5e-06 26.2 0.0 2.8 3 0 0 3 3 2 2 MarR family MarR PF01047.17 AIF85564.1 - 2.5e-07 30.2 0.2 8.7e-05 22.1 0.1 2.8 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.2 AIF85564.1 - 8.1e-06 25.5 0.2 0.0017 18.1 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Mga PF08280.6 AIF85564.1 - 1.4e-05 24.7 0.2 0.015 15.0 0.1 2.4 2 0 0 2 2 2 2 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.7 AIF85564.1 - 2.6e-05 23.7 0.2 8.6e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.5 AIF85564.1 - 7.7e-05 22.1 0.0 0.0007 19.1 0.1 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.15 AIF85564.1 - 9.8e-05 21.9 0.1 0.00021 20.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_23 PF13384.1 AIF85564.1 - 0.00013 21.4 0.1 0.00046 19.7 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.14 AIF85564.1 - 0.00056 19.5 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB EAP30 PF04157.11 AIF85564.1 - 0.00085 18.5 0.0 0.0022 17.1 0.0 1.6 1 1 1 2 2 2 1 EAP30/Vps36 family HTH_29 PF13551.1 AIF85564.1 - 0.00088 19.3 0.1 0.0026 17.8 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 AIF85564.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.1 AIF85564.1 - 0.0012 18.3 0.0 0.0034 16.9 0.0 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Sigma70_r4_2 PF08281.7 AIF85564.1 - 0.0013 18.1 0.8 0.016 14.6 0.1 2.6 3 0 0 3 3 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.1 AIF85564.1 - 0.0013 18.4 0.3 0.14 11.9 0.1 2.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Mga PF05043.8 AIF85564.1 - 0.0019 18.4 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 AIF85564.1 - 0.0026 16.8 0.0 0.0077 15.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 FeoC PF09012.5 AIF85564.1 - 0.005 16.5 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 FeoC like transcriptional regulator HTH_27 PF13463.1 AIF85564.1 - 0.0055 16.9 0.2 0.065 13.5 0.0 2.6 3 0 0 3 3 2 1 Winged helix DNA-binding domain HTH_10 PF04967.7 AIF85564.1 - 0.0079 15.7 0.2 0.03 13.8 0.1 1.9 2 0 0 2 2 2 1 HTH DNA binding domain GntR PF00392.16 AIF85564.1 - 0.01 15.2 0.3 0.085 12.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HxlR PF01638.12 AIF85564.1 - 0.012 15.2 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 HxlR-like helix-turn-helix GerE PF00196.14 AIF85564.1 - 0.013 14.8 0.5 0.32 10.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Fe_dep_repress PF01325.14 AIF85564.1 - 0.016 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF2089 PF09862.4 AIF85564.1 - 0.033 13.9 0.1 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) HTH_DeoR PF08220.7 AIF85564.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_7 PF02796.10 AIF85564.1 - 0.054 13.3 0.1 0.56 10.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase TNV_CP PF03898.8 AIF85564.1 - 0.061 12.3 0.5 0.13 11.2 0.3 1.5 1 1 0 1 1 1 0 Satellite tobacco necrosis virus coat protein TFIIE_alpha PF02002.12 AIF85564.1 - 0.061 12.8 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit YPEB PF14620.1 AIF85564.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation Sigma70_r4 PF04545.11 AIF85564.1 - 0.12 11.6 0.3 0.38 10.0 0.2 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 AIF85564.1 - 0.15 11.6 0.7 0.49 9.9 0.5 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain CMD PF02627.15 AIF85565.1 - 0.037 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Pro_dh PF01619.13 AIF85566.1 - 3.8e-39 134.5 0.0 1.1e-38 132.9 0.0 1.7 1 1 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.17 AIF85567.1 - 9.8e-150 498.8 0.3 1.3e-149 498.5 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AIF85567.1 - 4.6e-05 22.3 0.0 8.6e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Cupredoxin_1 PF13473.1 AIF85568.1 - 3.8e-08 33.1 0.1 5.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 AIF85568.1 - 0.003 17.7 0.5 0.0064 16.6 0.3 1.6 1 1 1 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Mmp37 PF09139.6 AIF85568.1 - 0.012 14.6 0.3 0.015 14.3 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 COX2 PF00116.15 AIF85568.1 - 0.054 13.3 0.1 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain RskA PF10099.4 AIF85568.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Peroxin-13_N PF04088.8 AIF85569.1 - 0.0086 16.0 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SLAC1 PF03595.12 AIF85569.1 - 0.018 13.6 0.7 0.023 13.3 0.5 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF4277 PF14104.1 AIF85569.1 - 0.019 15.1 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) Lipase_chap PF03280.9 AIF85569.1 - 0.088 12.3 1.9 0.3 10.5 1.1 1.8 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein DUF1049 PF06305.6 AIF85569.1 - 0.71 9.3 0.0 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) HTH_45 PF14947.1 AIF85570.1 - 9.3e-09 34.9 0.1 1.3e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix PadR PF03551.9 AIF85570.1 - 0.0099 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.17 AIF85570.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.1 AIF85570.1 - 0.057 13.4 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.1 AIF85570.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 AIF85570.1 - 0.092 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF505 PF04458.7 AIF85570.1 - 0.11 10.6 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) DUF1180 PF06679.7 AIF85571.1 - 0.012 15.5 2.2 0.012 15.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3357 PF11837.3 AIF85571.1 - 0.077 12.8 0.2 0.097 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3328 PF11807.3 AIF85571.1 - 0.08 12.6 0.1 0.08 12.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF2615 PF11027.3 AIF85571.1 - 0.14 12.0 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Myco_19_kDa PF05481.7 AIF85571.1 - 0.43 10.4 4.2 0.66 9.7 2.8 1.3 1 1 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen AAA_10 PF12846.2 AIF85572.1 - 1.3e-19 70.8 0.0 7.5e-19 68.2 0.0 2.1 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.12 AIF85572.1 - 8.2e-15 55.2 0.1 8.2e-15 55.2 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 DUF853 PF05872.7 AIF85572.1 - 1.5e-08 33.4 0.0 1.5e-08 33.4 0.0 3.3 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.13 AIF85572.1 - 2.8e-06 26.9 1.0 9.9e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 AIF85572.1 - 0.00051 18.7 0.0 0.0013 17.4 0.0 1.6 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 AIF85572.1 - 0.002 18.4 2.1 0.0026 18.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain CAP_assoc_N PF14504.1 AIF85572.1 - 0.021 14.5 0.9 1 9.0 0.0 2.6 3 0 0 3 3 3 0 CAP-associated N-terminal Sigma54_activat PF00158.21 AIF85572.1 - 0.063 12.7 0.8 1.4 8.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 AIF85572.1 - 0.083 13.7 2.9 0.2 12.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 AIF85572.1 - 0.43 10.8 0.0 0.43 10.8 0.0 3.1 3 1 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 AIF85572.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain RibD_C PF01872.12 AIF85573.1 - 5.1e-47 160.0 1.1 5.8e-47 159.9 0.8 1.0 1 0 0 1 1 1 1 RibD C-terminal domain His_biosynth PF00977.16 AIF85573.1 - 0.0026 17.0 0.9 0.93 8.7 0.0 2.1 1 1 1 2 2 2 2 Histidine biosynthesis protein Amidohydro_1 PF01979.15 AIF85574.1 - 7.3e-34 117.8 1.9 1.2e-33 117.1 1.3 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 AIF85574.1 - 5.8e-16 59.3 1.0 7.3e-15 55.7 0.7 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AIF85574.1 - 3.3e-12 46.3 7.0 6.8e-10 38.7 1.0 2.6 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 AIF85574.1 - 1.1e-09 37.9 0.1 4.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase GGDN PF05165.7 AIF85575.1 - 2.8e-57 193.5 0.8 3.1e-57 193.4 0.5 1.0 1 0 0 1 1 1 1 GGDN family Guanylate_cyc PF00211.15 AIF85575.1 - 0.0038 16.6 0.3 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DMRL_synthase PF00885.14 AIF85576.1 - 2.7e-38 130.8 0.7 3.3e-38 130.6 0.5 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ETF PF01012.16 AIF85576.1 - 0.0088 15.7 0.7 0.016 14.9 0.1 1.7 1 1 0 2 2 2 1 Electron transfer flavoprotein domain HSP70 PF00012.15 AIF85576.1 - 0.029 12.2 0.3 0.035 12.0 0.2 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF3866 PF12982.2 AIF85576.1 - 0.067 12.1 0.1 0.068 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DHBP_synthase PF00926.14 AIF85577.1 - 4e-64 215.4 0.6 4.6e-64 215.2 0.4 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Lum_binding PF00677.12 AIF85579.1 - 3.1e-47 158.3 0.3 4.5e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Antitoxin-MazE PF04014.13 AIF85579.1 - 0.017 14.8 1.1 4.4 7.1 0.0 3.2 3 0 0 3 3 3 0 Antidote-toxin recognition MazE Ldh_2 PF02615.9 AIF85579.1 - 0.089 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Hist_deacetyl PF00850.14 AIF85580.1 - 7.8e-73 245.4 0.1 9.4e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain SHMT PF00464.14 AIF85581.1 - 1.1e-72 244.5 0.1 1.7e-72 244.0 0.1 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 AIF85581.1 - 2.7e-06 26.7 0.0 4.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AIF85581.1 - 2.8e-05 23.2 0.0 7.9e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.8 AIF85581.1 - 0.00093 18.0 0.0 0.002 16.9 0.0 1.5 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Pyridoxal_deC PF00282.14 AIF85581.1 - 0.14 10.5 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Halo_GVPC PF05465.8 AIF85581.1 - 0.87 9.5 3.9 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF3150 PF11348.3 AIF85582.1 - 0.017 14.2 1.6 0.016 14.3 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Nucleopor_Nup85 PF07575.8 AIF85582.1 - 0.018 13.2 0.0 0.019 13.2 0.0 1.0 1 0 0 1 1 1 0 Nup85 Nucleoporin DUF2204 PF09970.4 AIF85583.1 - 0.033 13.6 0.2 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) AP2 PF00847.15 AIF85583.1 - 0.046 13.8 4.9 0.097 12.8 0.1 2.5 3 0 0 3 3 3 0 AP2 domain