# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Laminin_G_3 PF13385.1 AJW69701.1 - 8.4e-17 61.8 0.8 8.4e-17 61.8 0.5 4.9 4 1 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily YtkA PF13115.1 AJW69701.1 - 0.00074 19.8 0.0 0.78 10.1 0.0 3.3 3 0 0 3 3 3 2 YtkA-like Filamin PF00630.14 AJW69701.1 - 0.0024 18.3 0.3 0.044 14.3 0.0 3.2 3 0 0 3 3 3 1 Filamin/ABP280 repeat Atg14 PF10186.4 AJW69701.1 - 0.18 10.7 10.5 0.37 9.7 7.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4404 PF14357.1 AJW69701.1 - 1.2 9.5 9.5 0.9 9.9 4.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) LUC7 PF03194.10 AJW69701.1 - 2.4 7.6 6.8 5.1 6.5 4.7 1.5 1 0 0 1 1 1 0 LUC7 N_terminus Asp_Glu_race PF01177.17 AJW69702.1 - 7.9e-19 68.4 0.0 9.8e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Phi-29_GP4 PF05464.6 AJW69702.1 - 0.056 13.3 0.6 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Phi-29-like late genes activator (early protein GP4) Snf7 PF03357.16 AJW69703.1 - 0.0019 17.6 10.2 0.006 15.9 7.1 1.9 1 1 0 1 1 1 1 Snf7 DUF694 PF05107.7 AJW69703.1 - 0.0099 15.1 0.2 0.013 14.7 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF694) Baculo_PEP_C PF04513.7 AJW69703.1 - 0.015 15.1 3.0 0.53 10.1 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serine_rich PF08824.5 AJW69703.1 - 0.091 12.4 2.5 0.19 11.4 1.8 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain TMF_TATA_bd PF12325.3 AJW69703.1 - 0.13 11.9 3.7 0.36 10.5 2.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CCDC155 PF14662.1 AJW69703.1 - 0.2 11.2 5.7 0.13 11.8 2.5 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF1110 PF06533.7 AJW69703.1 - 0.22 11.3 2.3 0.3 10.8 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1110) Spc24 PF08286.6 AJW69703.1 - 0.32 10.7 4.1 0.28 10.8 0.4 2.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 AJW69703.1 - 0.9 9.8 5.4 7.8 6.8 0.6 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ALIX_LYPXL_bnd PF13949.1 AJW69703.1 - 1.1 8.1 6.9 6.1 5.7 4.8 2.4 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Flagellin_C PF00700.16 AJW69703.1 - 1.1 9.4 6.1 2.5 8.3 0.8 2.8 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF745 PF05335.8 AJW69703.1 - 5.1 6.5 9.4 4 6.9 1.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Glycos_transf_2 PF00535.21 AJW69704.1 - 7.2e-30 103.8 0.1 1.3e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.9 AJW69704.1 - 3.2e-19 69.0 10.9 1.2e-18 67.1 7.9 1.8 1 1 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.1 AJW69704.1 - 4.4e-09 36.4 0.0 6.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AJW69704.1 - 0.00038 19.6 0.3 0.0007 18.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.2 AJW69704.1 - 0.00092 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_transf_21 PF13506.1 AJW69704.1 - 0.0077 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1312 PF07009.6 AJW69706.1 - 0.027 14.2 0.2 0.029 14.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) UPF0180 PF03698.8 AJW69706.1 - 0.077 12.8 0.3 0.081 12.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) TP_methylase PF00590.15 AJW69708.1 - 5.2e-44 150.4 0.1 6.1e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PPR_1 PF12854.2 AJW69708.1 - 0.43 10.0 1.4 0.56 9.7 0.3 1.7 2 0 0 2 2 2 0 PPR repeat TP_methylase PF00590.15 AJW69709.1 - 4.9e-50 170.1 0.0 5.5e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Methyltransf_31 PF13847.1 AJW69710.1 - 2.1e-17 63.0 1.5 1.5e-16 60.2 0.3 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW69710.1 - 5.8e-17 62.2 0.1 8.4e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJW69710.1 - 1.3e-15 57.5 0.5 1.6e-15 57.1 0.3 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 AJW69710.1 - 1.7e-11 43.8 1.5 2.3e-11 43.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AJW69710.1 - 2.7e-11 43.1 0.1 8.3e-11 41.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 AJW69710.1 - 7.2e-09 35.1 0.2 9e-09 34.7 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 AJW69710.1 - 1.9e-08 34.0 0.1 5.1e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AJW69710.1 - 2.1e-07 30.9 0.0 4.4e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW69710.1 - 6e-07 29.7 0.0 2.4e-06 27.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 AJW69710.1 - 8e-07 28.3 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 AJW69710.1 - 1.1e-06 27.8 0.1 2.7e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase DUF633 PF04816.7 AJW69710.1 - 1.7e-06 27.5 1.1 2.1e-06 27.2 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) CMAS PF02353.15 AJW69710.1 - 2.7e-06 26.6 0.1 3.3e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 AJW69710.1 - 5.4e-06 25.9 0.0 8.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 AJW69710.1 - 2e-05 25.3 0.0 3.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW69710.1 - 2.5e-05 24.6 0.1 4.8e-05 23.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.11 AJW69710.1 - 2.6e-05 23.8 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein GCD14 PF08704.5 AJW69710.1 - 3.3e-05 23.5 0.0 5.1e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GidB PF02527.10 AJW69710.1 - 3.4e-05 23.0 0.3 4.4e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.7 AJW69710.1 - 6.7e-05 23.3 0.1 0.00021 21.7 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain RrnaAD PF00398.15 AJW69710.1 - 0.00031 19.8 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 AJW69710.1 - 0.00064 19.3 0.2 0.00096 18.7 0.1 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Nol1_Nop2_Fmu PF01189.12 AJW69710.1 - 0.0008 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_32 PF13679.1 AJW69710.1 - 0.001 18.7 0.1 0.003 17.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW69710.1 - 0.0022 17.7 0.0 0.003 17.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AJW69710.1 - 0.0036 17.2 0.1 0.04 13.9 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase NAC PF01849.13 AJW69710.1 - 0.0045 16.4 1.2 2.8 7.5 0.0 2.7 3 0 0 3 3 3 2 NAC domain MetW PF07021.7 AJW69710.1 - 0.0077 15.6 0.5 0.012 14.9 0.4 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 AJW69710.1 - 0.017 14.3 0.1 0.034 13.3 0.0 1.6 1 1 1 2 2 2 0 Tellurite resistance protein TehB AviRa PF11599.3 AJW69710.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DOT1 PF08123.8 AJW69710.1 - 0.021 14.1 0.2 0.037 13.3 0.1 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_5 PF01795.14 AJW69710.1 - 0.03 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family SIS PF01380.17 AJW69710.1 - 0.033 13.8 0.1 0.11 12.0 0.0 1.8 1 1 1 2 2 2 0 SIS domain FmrO PF07091.6 AJW69710.1 - 0.04 12.8 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) N6_Mtase PF02384.11 AJW69710.1 - 0.049 12.7 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Spermine_synth PF01564.12 AJW69710.1 - 0.14 11.1 1.7 0.41 9.5 0.1 1.9 1 1 1 2 2 2 0 Spermine/spermidine synthase Rab5ip PF07019.7 AJW69711.1 - 0.0031 17.5 5.8 0.0092 16.0 4.0 1.7 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) 7TM_GPCR_Srsx PF10320.4 AJW69711.1 - 0.0059 15.7 2.9 0.009 15.2 2.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4396 PF14342.1 AJW69711.1 - 0.013 15.5 1.5 3.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Herpes_UL43 PF05072.8 AJW69711.1 - 0.014 14.2 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein PBP1_TM PF14812.1 AJW69711.1 - 0.032 14.5 0.1 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_A4 PF01828.12 AJW69711.1 - 0.08 11.9 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase A4 family DUF543 PF04418.7 AJW69711.1 - 0.099 12.6 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF543) DUF1279 PF06916.8 AJW69711.1 - 0.14 12.4 0.7 2 8.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) ATP-synt_8 PF00895.15 AJW69711.1 - 0.54 10.5 0.1 0.54 10.5 0.1 2.7 3 1 1 4 4 4 0 ATP synthase protein 8 Fig1 PF12351.3 AJW69711.1 - 0.96 9.3 3.8 0.36 10.7 0.8 1.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF202 PF02656.10 AJW69711.1 - 7.2 6.9 6.1 31 4.8 4.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) FbpA PF05833.6 AJW69712.1 - 7.7e-45 153.2 10.3 9.8e-45 152.9 7.1 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 AJW69712.1 - 1.6e-15 56.7 0.0 4.1e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Tweety PF04906.8 AJW69712.1 - 0.3 9.4 7.2 1.3 7.3 0.6 2.2 1 1 1 2 2 2 0 Tweety DUF126 PF01989.11 AJW69713.1 - 1.3e-31 108.1 0.1 1.8e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF126 DUF521 PF04412.8 AJW69714.1 - 4.8e-101 338.1 0.1 9.1e-101 337.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF521) HhH-GPD PF00730.20 AJW69715.1 - 1.4e-23 83.2 0.1 2.1e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AJW69715.1 - 5.8e-09 35.1 0.0 2e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2400 PF09674.5 AJW69715.1 - 0.00036 20.2 0.1 0.0051 16.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_5 PF14520.1 AJW69715.1 - 0.023 14.8 0.2 0.15 12.2 0.1 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix domain DUF4028 PF13220.1 AJW69715.1 - 0.067 12.8 0.5 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) EndIII_4Fe-2S PF10576.4 AJW69715.1 - 0.94 9.7 4.5 1.8 8.8 3.1 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III ATP-sulfurylase PF01747.12 AJW69717.1 - 2.1e-88 295.2 0.0 4e-88 294.2 0.0 1.4 2 0 0 2 2 2 1 ATP-sulfurylase PUA_2 PF14306.1 AJW69717.1 - 1.4e-46 157.7 0.0 2.9e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.14 AJW69718.1 - 5.5e-45 153.3 0.0 6.5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glyco_trans_1_3 PF13528.1 AJW69720.1 - 3.6e-14 52.6 0.0 9.4e-10 38.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 Alg14 PF08660.6 AJW69720.1 - 0.0056 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Cas_Csa5 PF09702.5 AJW69720.1 - 0.11 12.6 0.5 0.73 9.9 0.1 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) KH_5 PF13184.1 AJW69720.1 - 0.28 11.0 2.0 1.2 9.0 0.4 2.9 3 0 0 3 3 3 0 NusA-like KH domain Ribosomal_L32p PF01783.18 AJW69721.1 - 0.015 15.4 0.0 0.015 15.4 0.0 2.3 3 0 0 3 3 3 0 Ribosomal L32p protein family OrfB_Zn_ribbon PF07282.6 AJW69721.1 - 0.021 14.4 0.9 0.52 9.9 0.1 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 AJW69721.1 - 0.035 13.4 0.5 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2296 PF10058.4 AJW69721.1 - 0.22 11.3 1.5 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) PhnA_Zn_Ribbon PF08274.7 AJW69721.1 - 0.3 10.8 2.5 2 8.2 0.7 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.2 AJW69721.1 - 0.79 9.5 5.0 12 5.8 0.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 AJW69721.1 - 0.8 9.3 3.3 6 6.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 AJW69721.1 - 0.88 9.5 3.3 19 5.2 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Nudix_N_2 PF14803.1 AJW69721.1 - 1.7 8.3 4.1 11 5.7 0.1 2.9 2 1 0 2 2 2 0 Nudix N-terminal Cna_B PF05738.8 AJW69722.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Cna protein B-type domain G10 PF01125.12 AJW69722.1 - 0.018 14.6 1.0 1.3 8.5 0.1 2.1 1 1 1 2 2 2 0 G10 protein adh_short PF00106.20 AJW69723.1 - 3.8e-36 124.5 0.0 4.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AJW69723.1 - 6.6e-14 51.9 0.0 1.5e-13 50.8 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 AJW69723.1 - 3.2e-13 50.0 0.3 4e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 AJW69723.1 - 2.9e-05 23.7 0.0 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 AJW69723.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AJW69723.1 - 0.0079 15.1 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 AJW69723.1 - 0.042 12.9 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 AJW69723.1 - 0.31 11.1 1.4 0.35 10.9 0.2 1.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UPF0104 PF03706.8 AJW69724.1 - 1.3e-24 87.0 18.5 1.7e-24 86.6 12.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) SIS PF01380.17 AJW69724.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 SIS domain DUF3353 PF11833.3 AJW69724.1 - 0.14 11.6 3.9 2.3 7.6 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) UPF0233 PF06781.7 AJW69724.1 - 0.33 10.5 8.0 3.4 7.3 0.3 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) DUF2627 PF11118.3 AJW69724.1 - 0.61 10.2 8.9 2.5 8.2 2.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) ATP_bind_1 PF03029.12 AJW69726.1 - 9.2e-57 192.3 0.0 1.1e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 AJW69726.1 - 0.00012 21.6 0.1 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 AJW69726.1 - 0.0002 21.4 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 AJW69726.1 - 0.00046 19.7 0.3 0.0013 18.2 0.2 1.9 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 AJW69726.1 - 0.00076 18.3 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein DUF2075 PF09848.4 AJW69726.1 - 0.0021 17.1 0.1 0.0044 16.0 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 AJW69726.1 - 0.0035 18.1 0.1 0.01 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 AJW69726.1 - 0.0037 16.7 0.3 0.11 11.9 0.2 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.4 AJW69726.1 - 0.014 14.0 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 AJW69726.1 - 0.032 14.3 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 AJW69726.1 - 0.04 14.2 0.1 0.096 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 AJW69726.1 - 0.049 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 AJW69726.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 AJW69726.1 - 0.058 12.8 0.2 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 AJW69726.1 - 0.058 13.0 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain PIF1 PF05970.9 AJW69726.1 - 0.084 11.7 0.1 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase T2SE PF00437.15 AJW69726.1 - 0.11 11.4 0.2 0.22 10.3 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 AJW69726.1 - 0.22 10.9 2.8 7 6.0 1.9 2.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GHMP_kinases_N PF00288.21 AJW69727.1 - 2.7e-16 59.3 2.4 6.1e-16 58.2 1.7 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJW69727.1 - 1.1e-07 31.9 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal QueC PF06508.8 AJW69728.1 - 4.1e-48 163.4 0.1 4.7e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 AJW69728.1 - 3.5e-05 23.0 0.1 4.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AJW69728.1 - 9.2e-05 22.0 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AJW69728.1 - 0.0077 15.1 0.1 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 NAD synthase GpcrRhopsn4 PF10192.4 AJW69729.1 - 0.06 12.5 0.3 0.077 12.1 0.2 1.2 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF4118 PF13493.1 AJW69729.1 - 0.13 12.5 0.9 0.18 12.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) GTP_cyclohydroI PF01227.17 AJW69730.1 - 2.6e-63 212.5 0.0 3e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AJW69730.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein PDEase_I PF00233.14 AJW69730.1 - 0.0057 16.4 0.1 0.014 15.1 0.0 1.6 1 1 1 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Fer4_14 PF13394.1 AJW69731.1 - 7e-16 58.3 0.9 2.2e-15 56.7 0.0 1.9 1 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJW69731.1 - 1.5e-14 54.2 1.6 7.3e-14 52.0 0.1 2.1 1 1 1 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 AJW69731.1 - 9e-11 42.2 0.1 1.2e-10 41.8 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily NfeD PF01957.13 AJW69732.1 - 0.019 15.0 2.6 0.021 14.9 1.8 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF981 PF06168.6 AJW69732.1 - 0.085 12.6 2.2 0.099 12.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) SKG6 PF08693.5 AJW69732.1 - 0.13 11.5 4.9 0.27 10.5 1.2 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Tetraspannin PF00335.15 AJW69732.1 - 0.28 10.4 4.2 0.33 10.1 2.9 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF3185 PF11381.3 AJW69732.1 - 8.1 6.2 8.6 2.7e+02 1.4 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) FliS PF02561.9 AJW69733.1 - 0.0041 16.9 0.3 0.0041 16.9 0.2 3.6 2 1 1 3 3 3 1 Flagellar protein FliS DUF4363 PF14276.1 AJW69733.1 - 0.026 14.2 16.7 3.1 7.5 0.0 5.4 3 2 2 5 5 5 0 Domain of unknown function (DUF4363) FCD PF07729.7 AJW69733.1 - 0.04 14.2 3.2 2.9 8.2 0.0 3.2 2 1 1 3 3 3 0 FCD domain DUF2267 PF10025.4 AJW69733.1 - 0.06 13.4 3.3 0.22 11.5 0.5 2.6 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) CPSase_L_D3 PF02787.14 AJW69733.1 - 0.08 12.7 9.6 1.2 8.9 2.9 3.5 2 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Ubiquitin_3 PF14836.1 AJW69733.1 - 0.11 12.2 1.4 0.28 10.8 0.2 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain DUF1741 PF08427.5 AJW69733.1 - 0.15 11.4 16.2 0.016 14.6 3.7 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF1741) Peptidase_M75 PF09375.5 AJW69733.1 - 0.25 10.6 9.0 4.1 6.6 0.0 3.2 2 1 0 3 3 3 0 Imelysin Ribosomal_L22 PF00237.14 AJW69733.1 - 0.72 9.8 4.7 1.2 9.1 0.1 3.1 2 2 1 3 3 3 0 Ribosomal protein L22p/L17e MerR-DNA-bind PF09278.6 AJW69733.1 - 0.9 9.9 15.2 1.9 8.9 0.2 3.9 4 1 0 4 4 3 0 MerR, DNA binding GTPase_Cys_C PF12631.2 AJW69733.1 - 3.2 8.2 10.8 15 6.0 0.4 4.1 3 2 1 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Prp18 PF02840.10 AJW69733.1 - 3.3 7.5 12.9 0.65 9.8 1.7 3.4 2 2 2 4 4 4 0 Prp18 domain ALMT PF11744.3 AJW69733.1 - 4.4 5.8 12.4 0.56 8.8 3.1 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter TPR_6 PF13174.1 AJW69733.1 - 8.5 7.0 7.6 47 4.7 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat HTH_24 PF13412.1 AJW69734.1 - 6.5e-05 22.2 0.1 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AJW69734.1 - 0.027 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 MarR family MarR PF01047.17 AJW69734.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 MarR family GntR PF00392.16 AJW69734.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_45 PF14947.1 AJW69735.1 - 2e-10 40.3 0.0 2.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 AJW69735.1 - 8.9e-06 25.2 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AJW69735.1 - 0.00026 21.2 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.1 AJW69735.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) RNA_pol_Rpc34 PF05158.7 AJW69735.1 - 0.049 12.8 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF2250 PF10007.4 AJW69735.1 - 0.05 13.5 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Mrr_N PF14338.1 AJW69735.1 - 0.056 13.5 0.0 0.6 10.2 0.0 2.0 1 1 1 2 2 2 0 Mrr N-terminal domain TrmB PF01978.14 AJW69735.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 AJW69735.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 MarR family RAG2_PHD PF13341.1 AJW69736.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 RAG2 PHD domain AAA_5 PF07728.9 AJW69737.1 - 0.0039 16.9 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF1664 PF07889.7 AJW69738.1 - 0.00018 21.3 6.3 0.00024 20.8 3.7 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF812 PF05667.6 AJW69738.1 - 0.00094 17.8 7.4 0.0011 17.6 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMF_DNA_bd PF12329.3 AJW69738.1 - 0.0011 18.7 10.1 0.0011 18.7 7.0 2.6 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 AJW69738.1 - 0.0015 17.7 0.6 0.0016 17.6 0.4 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Spc7 PF08317.6 AJW69738.1 - 0.0026 16.5 9.7 0.0026 16.5 6.7 1.6 1 1 1 2 2 2 2 Spc7 kinetochore protein Laminin_II PF06009.7 AJW69738.1 - 0.003 17.2 6.0 0.0047 16.6 4.2 1.4 1 0 0 1 1 1 1 Laminin Domain II AAA_13 PF13166.1 AJW69738.1 - 0.0048 15.4 8.7 0.0051 15.3 6.1 1.1 1 0 0 1 1 1 1 AAA domain Prefoldin PF02996.12 AJW69738.1 - 0.0049 16.4 8.0 0.026 14.1 1.5 2.6 1 1 1 2 2 2 1 Prefoldin subunit IncA PF04156.9 AJW69738.1 - 0.0074 15.9 9.1 0.0096 15.5 6.3 1.2 1 0 0 1 1 1 1 IncA protein Tropomyosin_1 PF12718.2 AJW69738.1 - 0.0094 15.8 16.7 0.033 14.0 11.2 2.2 1 1 0 1 1 1 1 Tropomyosin like Laminin_I PF06008.9 AJW69738.1 - 0.01 15.1 3.7 0.014 14.7 2.6 1.2 1 0 0 1 1 1 0 Laminin Domain I Baculo_PEP_C PF04513.7 AJW69738.1 - 0.023 14.5 0.1 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 AJW69738.1 - 0.026 14.3 3.8 0.21 11.4 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) YlbD_coat PF14071.1 AJW69738.1 - 0.028 14.4 4.7 3.4 7.7 0.1 2.7 1 1 0 2 2 2 0 Putative coat protein Flagellin_C PF00700.16 AJW69738.1 - 0.028 14.5 2.2 0.17 12.0 0.2 2.2 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DUF972 PF06156.8 AJW69738.1 - 0.034 14.5 2.9 0.034 14.5 2.0 2.4 1 1 2 3 3 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 AJW69738.1 - 0.036 13.9 7.9 0.61 9.9 5.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 AJW69738.1 - 0.041 13.1 5.0 1.4 8.1 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 AJW69738.1 - 0.054 11.8 9.3 0.068 11.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4618 PF15397.1 AJW69738.1 - 0.061 12.6 9.1 0.3 10.4 6.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4200 PF13863.1 AJW69738.1 - 0.065 13.1 12.2 0.045 13.6 5.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 AJW69738.1 - 0.082 11.8 5.7 0.1 11.5 3.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 AJW69738.1 - 0.091 13.0 5.8 0.31 11.3 3.3 2.1 1 1 0 1 1 1 0 Snapin/Pallidin DUF3552 PF12072.3 AJW69738.1 - 0.12 11.6 11.0 0.2 10.8 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ALIX_LYPXL_bnd PF13949.1 AJW69738.1 - 0.12 11.3 11.1 0.36 9.7 7.7 1.8 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV ArsR PF09824.4 AJW69738.1 - 0.14 11.4 2.9 0.13 11.5 1.1 1.7 1 1 1 2 2 2 0 ArsR transcriptional regulator FemAB PF02388.11 AJW69738.1 - 0.19 10.3 2.3 0.23 10.1 1.6 1.2 1 0 0 1 1 1 0 FemAB family Spectrin PF00435.16 AJW69738.1 - 0.2 11.9 6.3 0.76 10.0 3.2 2.4 1 1 1 2 2 2 0 Spectrin repeat Nup54 PF13874.1 AJW69738.1 - 0.2 11.3 3.4 0.3 10.7 2.3 1.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 End3 PF12761.2 AJW69738.1 - 0.21 11.2 6.2 0.1 12.2 2.6 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TBPIP PF07106.8 AJW69738.1 - 0.24 10.9 11.6 0.42 10.1 3.2 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 AJW69738.1 - 0.27 11.5 5.5 8.1 6.7 3.8 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cortex-I_coil PF09304.5 AJW69738.1 - 0.28 11.2 9.2 0.47 10.5 5.5 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil Prefoldin_2 PF01920.15 AJW69738.1 - 0.32 10.7 10.9 1.9 8.3 3.6 2.6 1 1 1 2 2 2 0 Prefoldin subunit APG6 PF04111.7 AJW69738.1 - 0.34 9.8 7.5 0.43 9.5 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 AJW69738.1 - 0.36 10.4 10.2 0.75 9.4 7.0 1.7 1 1 0 1 1 1 0 Mnd1 family GAS PF13851.1 AJW69738.1 - 0.42 9.7 11.7 0.54 9.4 7.7 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sipho_Gp157 PF05565.6 AJW69738.1 - 0.43 10.1 10.9 5.4 6.5 4.5 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 DUF745 PF05335.8 AJW69738.1 - 0.48 9.9 3.3 0.61 9.5 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) GldM_N PF12081.3 AJW69738.1 - 0.51 9.8 8.3 0.39 10.2 1.2 2.0 1 1 1 2 2 2 0 GldM N-terminal domain DUF2408 PF10303.4 AJW69738.1 - 0.54 10.3 6.3 0.15 12.2 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Syntaxin PF00804.20 AJW69738.1 - 0.54 10.4 11.3 0.66 10.1 5.1 2.2 1 1 1 2 2 2 0 Syntaxin BLOC1_2 PF10046.4 AJW69738.1 - 0.56 10.3 8.2 9.7 6.3 5.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YscO PF07321.7 AJW69738.1 - 0.57 9.9 6.3 0.92 9.3 2.3 1.9 1 1 1 2 2 2 0 Type III secretion protein YscO DUF4363 PF14276.1 AJW69738.1 - 0.75 9.5 6.3 0.96 9.1 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) COG2 PF06148.6 AJW69738.1 - 0.93 9.3 8.2 1.9 8.3 0.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec2p PF06428.6 AJW69738.1 - 0.96 9.3 13.0 2.8 7.8 0.4 3.0 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p CENP-Q PF13094.1 AJW69738.1 - 1.1 9.2 7.1 1.7 8.6 4.9 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMPIT PF07851.8 AJW69738.1 - 1.2 8.1 3.9 1.4 7.8 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein ATG16 PF08614.6 AJW69738.1 - 1.2 8.9 10.1 1.5 8.5 6.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 AJW69738.1 - 1.3 6.7 7.1 1.4 6.6 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF848 PF05852.6 AJW69738.1 - 1.4 8.8 8.3 1 9.2 4.4 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HR1 PF02185.11 AJW69738.1 - 1.4 8.7 10.3 2.4 7.9 6.3 2.1 1 1 1 2 2 2 0 Hr1 repeat TMCO5 PF14992.1 AJW69738.1 - 1.5 7.8 13.7 1.9 7.5 9.5 1.1 1 0 0 1 1 1 0 TMCO5 family Fib_alpha PF08702.5 AJW69738.1 - 1.6 8.8 8.0 3.4 7.7 3.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Macoilin PF09726.4 AJW69738.1 - 1.8 6.7 9.7 2.3 6.4 6.7 1.2 1 0 0 1 1 1 0 Transmembrane protein KH_5 PF13184.1 AJW69738.1 - 2 8.3 7.4 4.4 7.1 0.6 2.6 1 1 0 2 2 2 0 NusA-like KH domain DUF904 PF06005.7 AJW69738.1 - 2.3 8.5 10.1 20 5.5 7.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 AJW69738.1 - 2.4 7.7 10.3 1.4 8.5 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 AJW69738.1 - 3.4 7.6 11.0 3.9 7.4 2.2 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.4 AJW69738.1 - 4.6 7.4 5.9 3.3 7.9 2.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spc42p PF11544.3 AJW69738.1 - 4.9 7.1 9.9 0.58 10.1 0.2 2.8 1 1 1 2 2 2 0 Spindle pole body component Spc42p Bap31 PF05529.7 AJW69738.1 - 8.7 5.7 7.4 9.2 5.6 4.1 1.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Nup54 PF13874.1 AJW69739.1 - 0.0041 16.7 1.6 0.0075 15.9 1.1 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Snf7 PF03357.16 AJW69739.1 - 0.0042 16.4 3.3 0.0063 15.9 2.3 1.3 1 1 0 1 1 1 1 Snf7 ADIP PF11559.3 AJW69739.1 - 0.032 14.1 0.9 0.05 13.5 0.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GHMP_kinases_C PF08544.8 AJW69739.1 - 0.04 14.1 1.0 1.8 8.8 0.0 2.8 1 1 1 2 2 2 0 GHMP kinases C terminal DUF2806 PF10987.3 AJW69739.1 - 0.059 12.8 0.2 0.09 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) adh_short_C2 PF13561.1 AJW69741.1 - 3.3e-41 141.6 0.0 4e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AJW69741.1 - 2.6e-29 102.3 0.0 3.2e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AJW69741.1 - 8.6e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AJW69741.1 - 7.8e-05 22.2 0.3 0.00021 20.8 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AJW69741.1 - 0.013 14.5 0.1 0.025 13.6 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 AJW69741.1 - 0.07 13.1 0.2 0.083 12.8 0.1 1.3 1 1 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 AJW69741.1 - 0.089 12.8 0.2 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 AJW69741.1 - 0.17 11.5 0.6 0.34 10.5 0.4 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2842 PF11003.3 AJW69742.1 - 0.028 14.2 4.6 0.61 9.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) YesK PF14150.1 AJW69742.1 - 0.056 13.5 1.6 0.071 13.2 1.1 1.1 1 0 0 1 1 1 0 YesK-like protein Tetraspannin PF00335.15 AJW69742.1 - 0.18 11.0 1.5 0.21 10.8 1.0 1.0 1 0 0 1 1 1 0 Tetraspanin family SdpI PF13630.1 AJW69742.1 - 0.31 10.7 4.5 0.41 10.3 3.1 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Mem_trans PF03547.13 AJW69742.1 - 0.32 9.2 3.1 0.36 9.0 2.1 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF2953 PF11167.3 AJW69742.1 - 0.72 9.8 3.0 17 5.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2953) Inositol_P PF00459.20 AJW69743.1 - 2e-53 181.4 0.0 2.2e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 AJW69743.1 - 0.015 14.1 0.2 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase APS_kinase PF01583.15 AJW69744.1 - 3.8e-50 169.6 0.0 4.4e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 AJW69744.1 - 3.8e-08 33.3 0.0 4.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJW69744.1 - 4.5e-05 24.2 0.0 6.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AJW69744.1 - 0.00013 22.3 0.0 0.00043 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AJW69744.1 - 0.00023 20.3 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 AJW69744.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Ferrochelatase PF00762.14 AJW69744.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.4 1 1 1 2 2 2 0 Ferrochelatase CPT PF07931.7 AJW69744.1 - 0.053 13.1 0.0 2.1 7.9 0.0 2.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 AJW69744.1 - 0.064 13.2 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 AJW69744.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Hemerythrin PF01814.18 AJW69745.1 - 2.2e-12 47.2 1.7 2.3e-12 47.2 0.1 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain HSBP1 PF06825.7 AJW69745.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF1053 PF06327.9 AJW69745.1 - 0.085 13.2 0.3 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) TDH PF03347.8 AJW69745.1 - 0.088 12.3 0.2 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Vibrio thermostable direct hemolysin Na_H_Exchanger PF00999.16 AJW69746.1 - 9.6e-39 132.9 48.5 1.2e-38 132.6 33.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TFIIB PF00382.14 AJW69747.1 - 1e-33 114.9 7.1 1.6e-17 63.0 0.4 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW69747.1 - 2.4e-11 42.7 0.4 4e-11 42.0 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_11 PF08279.7 AJW69747.1 - 0.0036 16.9 0.1 0.06 12.9 0.0 2.5 2 0 0 2 2 2 1 HTH domain Sigma70_r4 PF04545.11 AJW69747.1 - 0.0064 15.7 0.0 0.017 14.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 zf-ribbon_3 PF13248.1 AJW69747.1 - 0.0071 15.5 1.0 0.015 14.4 0.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Cyclin_N PF00134.18 AJW69747.1 - 0.0086 15.6 0.2 0.047 13.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4_2 PF08281.7 AJW69747.1 - 0.018 14.4 0.3 0.22 11.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 AJW69747.1 - 0.026 14.0 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DZR PF12773.2 AJW69747.1 - 0.061 13.1 0.6 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon RPA_interact_C PF14768.1 AJW69747.1 - 0.069 13.5 0.8 0.15 12.4 0.1 1.9 2 0 0 2 2 1 0 Replication protein A interacting C-terminal zinc_ribbon_2 PF13240.1 AJW69747.1 - 0.07 12.6 2.4 0.12 11.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HTH_23 PF13384.1 AJW69747.1 - 0.094 12.3 2.1 0.17 11.5 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain Baculo_ME53 PF06061.6 AJW69747.1 - 0.11 11.5 0.2 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 CARDB PF07705.6 AJW69748.1 - 0.00074 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.4 AJW69748.1 - 0.057 13.4 0.0 0.52 10.4 0.0 2.4 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4508 PF14969.1 AJW69749.1 - 0.056 13.4 0.1 0.093 12.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) E2_bind PF08825.5 AJW69749.1 - 0.97 9.2 6.9 2.9 7.6 1.0 2.8 1 1 2 3 3 3 0 E2 binding domain JmjN PF02375.12 AJW69750.1 - 0.1 12.1 0.8 0.24 10.9 0.0 2.0 3 0 0 3 3 3 0 jmjN domain CRCB PF02537.10 AJW69752.1 - 3e-25 88.3 7.3 3.4e-25 88.1 5.1 1.0 1 0 0 1 1 1 1 CrcB-like protein DUF2104 PF09877.4 AJW69752.1 - 0.031 14.2 0.8 0.048 13.6 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) DUF1059 PF06348.6 AJW69753.1 - 3.3e-07 30.0 0.2 4.6e-07 29.5 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1059) TFIIB PF00382.14 AJW69754.1 - 1.5e-32 111.2 1.3 3.1e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW69754.1 - 3.7e-05 22.9 2.1 4.4e-05 22.7 0.2 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 AJW69754.1 - 0.00011 21.7 0.2 0.23 11.0 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain HTH_11 PF08279.7 AJW69754.1 - 0.096 12.3 0.8 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 HTH domain IncA PF04156.9 AJW69755.1 - 2.8e-07 30.3 0.5 4e-07 29.8 0.3 1.2 1 1 0 1 1 1 1 IncA protein Leu_zip PF15294.1 AJW69755.1 - 8.7e-05 21.7 6.2 0.00012 21.3 4.3 1.1 1 0 0 1 1 1 1 Leucine zipper TSC22 PF01166.13 AJW69755.1 - 0.00028 20.7 4.1 0.004 17.0 0.6 2.5 1 1 1 2 2 2 1 TSC-22/dip/bun family CENP-Q PF13094.1 AJW69755.1 - 0.00035 20.6 1.7 0.00042 20.3 1.2 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 AJW69755.1 - 0.00049 18.8 5.4 0.00064 18.4 3.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_1 PF00170.16 AJW69755.1 - 0.00058 19.7 6.0 0.0059 16.5 0.9 2.2 1 1 1 2 2 2 2 bZIP transcription factor Sipho_Gp157 PF05565.6 AJW69755.1 - 0.00065 19.3 2.3 0.00095 18.7 1.6 1.3 1 0 0 1 1 1 1 Siphovirus Gp157 APG6 PF04111.7 AJW69755.1 - 0.00067 18.8 1.4 0.00083 18.4 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 ADIP PF11559.3 AJW69755.1 - 0.00069 19.5 5.5 0.00088 19.1 3.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 AJW69755.1 - 0.00074 19.3 1.1 0.0011 18.8 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.16 AJW69755.1 - 0.0011 18.5 3.4 0.0013 18.2 2.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein HAP1_N PF04849.8 AJW69755.1 - 0.0012 17.8 0.6 0.0013 17.7 0.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region FlxA PF14282.1 AJW69755.1 - 0.0019 18.0 5.1 0.0029 17.5 3.5 1.3 1 0 0 1 1 1 1 FlxA-like protein Phage_GP20 PF06810.6 AJW69755.1 - 0.002 17.6 7.2 0.0028 17.1 5.0 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 RNA_pol_Rpb1_1 PF04997.7 AJW69755.1 - 0.0025 17.1 4.0 0.0032 16.7 2.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DivIC PF04977.10 AJW69755.1 - 0.0025 17.2 7.7 0.015 14.7 4.3 2.2 1 1 1 2 2 2 2 Septum formation initiator AAA_13 PF13166.1 AJW69755.1 - 0.0028 16.1 4.1 0.0034 15.9 2.9 1.0 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 AJW69755.1 - 0.0037 17.1 6.7 0.0062 16.3 4.6 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 AJW69755.1 - 0.0038 17.2 4.5 0.0062 16.5 3.1 1.3 1 0 0 1 1 1 1 DivIVA protein Atg14 PF10186.4 AJW69755.1 - 0.0038 16.2 0.1 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 AJW69755.1 - 0.0048 16.7 4.8 0.0065 16.3 3.3 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_2 PF07716.10 AJW69755.1 - 0.0048 16.6 7.2 0.075 12.8 0.6 2.4 1 1 1 2 2 2 2 Basic region leucine zipper DUF3450 PF11932.3 AJW69755.1 - 0.0051 16.1 3.2 0.0066 15.7 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF812 PF05667.6 AJW69755.1 - 0.0054 15.2 0.8 0.0056 15.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 AJW69755.1 - 0.0055 14.6 0.3 0.0055 14.6 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HALZ PF02183.13 AJW69755.1 - 0.0062 16.2 5.3 0.5 10.1 0.3 2.3 1 1 2 3 3 3 2 Homeobox associated leucine zipper CCDC155 PF14662.1 AJW69755.1 - 0.0063 16.1 6.7 0.0084 15.7 4.6 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 GOLGA2L5 PF15070.1 AJW69755.1 - 0.0064 15.0 0.9 0.0081 14.6 0.7 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 NTR2 PF15458.1 AJW69755.1 - 0.0081 15.4 3.8 0.01 15.1 2.6 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF4164 PF13747.1 AJW69755.1 - 0.0087 16.1 5.9 0.015 15.4 4.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) DUF342 PF03961.8 AJW69755.1 - 0.014 13.8 1.3 0.017 13.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 AJW69755.1 - 0.014 15.2 6.4 0.023 14.6 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Orthopox_A5L PF06193.6 AJW69755.1 - 0.015 15.2 6.0 0.023 14.6 4.2 1.3 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like HOOK PF05622.7 AJW69755.1 - 0.016 13.0 3.1 0.019 12.7 2.2 1.0 1 0 0 1 1 1 0 HOOK protein Bap31 PF05529.7 AJW69755.1 - 0.016 14.6 2.6 0.022 14.2 1.8 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like BRE1 PF08647.6 AJW69755.1 - 0.017 15.0 6.9 0.025 14.5 4.8 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase HeLo PF14479.1 AJW69755.1 - 0.018 14.7 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation Tektin PF03148.9 AJW69755.1 - 0.019 13.5 3.9 0.023 13.2 2.7 1.1 1 0 0 1 1 1 0 Tektin family EMP24_GP25L PF01105.19 AJW69755.1 - 0.02 14.6 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2968 PF11180.3 AJW69755.1 - 0.022 14.1 1.8 0.031 13.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3584 PF12128.3 AJW69755.1 - 0.023 12.0 3.3 0.028 11.7 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cep57_MT_bd PF06657.8 AJW69755.1 - 0.023 14.6 1.6 0.044 13.7 1.1 1.6 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Kinesin-relat_1 PF12711.2 AJW69755.1 - 0.024 15.0 1.3 0.041 14.2 0.9 1.4 1 0 0 1 1 1 0 Kinesin motor DUF904 PF06005.7 AJW69755.1 - 0.024 14.9 10.1 0.18 12.0 7.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TBPIP PF07106.8 AJW69755.1 - 0.025 14.1 6.2 0.033 13.7 4.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliD_C PF07195.7 AJW69755.1 - 0.026 13.8 1.6 0.035 13.4 1.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TMF_TATA_bd PF12325.3 AJW69755.1 - 0.029 14.1 5.9 0.11 12.2 4.0 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 AJW69755.1 - 0.031 14.0 3.7 0.031 14.0 2.6 1.9 1 1 1 2 2 2 0 Prefoldin subunit RmuC PF02646.11 AJW69755.1 - 0.031 13.1 1.5 0.043 12.6 1.0 1.2 1 0 0 1 1 1 0 RmuC family DUF2205 PF10224.4 AJW69755.1 - 0.033 13.7 6.9 0.16 11.5 0.5 2.6 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4140 PF13600.1 AJW69755.1 - 0.04 14.3 2.7 0.12 12.7 1.9 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Herpes_UL6 PF01763.11 AJW69755.1 - 0.041 12.0 0.4 0.047 11.8 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like AAA_27 PF13514.1 AJW69755.1 - 0.046 11.4 0.8 0.054 11.1 0.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3573 PF12097.3 AJW69755.1 - 0.046 12.3 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Striatin PF08232.7 AJW69755.1 - 0.047 14.0 2.2 0.071 13.4 1.5 1.4 1 0 0 1 1 1 0 Striatin family Tropomyosin_1 PF12718.2 AJW69755.1 - 0.049 13.4 5.7 0.065 13.0 4.0 1.2 1 0 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.4 AJW69755.1 - 0.053 13.6 6.4 0.071 13.2 4.4 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 AJW69755.1 - 0.058 12.5 6.9 0.099 11.8 4.4 1.4 1 1 1 2 2 1 0 Growth-arrest specific micro-tubule binding LURAP PF14854.1 AJW69755.1 - 0.063 13.0 1.2 0.084 12.5 0.8 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4515 PF14988.1 AJW69755.1 - 0.063 12.9 5.3 0.068 12.8 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) Corona_S2 PF01601.11 AJW69755.1 - 0.065 11.3 0.3 0.086 10.9 0.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TLE_N PF03920.10 AJW69755.1 - 0.069 12.9 0.7 0.13 12.0 0.2 1.5 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain RTBV_P46 PF06216.6 AJW69755.1 - 0.072 11.9 1.2 0.093 11.5 0.8 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF465 PF04325.8 AJW69755.1 - 0.075 12.7 6.7 0.39 10.4 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF465) DUF1465 PF07323.7 AJW69755.1 - 0.075 12.5 0.9 0.11 12.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF972 PF06156.8 AJW69755.1 - 0.078 13.3 3.8 0.12 12.7 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 AJW69755.1 - 0.089 11.9 0.5 0.13 11.4 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1180 PF06679.7 AJW69755.1 - 0.09 12.6 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Taxilin PF09728.4 AJW69755.1 - 0.093 11.7 7.4 0.14 11.2 5.1 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CALCOCO1 PF07888.6 AJW69755.1 - 0.098 10.9 5.9 0.13 10.5 4.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.3 AJW69755.1 - 0.1 12.3 11.1 0.19 11.5 6.7 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 AJW69755.1 - 0.13 11.8 8.3 0.89 9.2 0.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.6 AJW69755.1 - 0.13 11.9 6.8 0.2 11.3 4.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 K-box PF01486.12 AJW69755.1 - 0.15 11.8 5.6 1.4 8.7 3.9 2.0 1 1 0 1 1 1 0 K-box region Jnk-SapK_ap_N PF09744.4 AJW69755.1 - 0.15 12.0 4.1 0.23 11.4 2.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Herpes_BLRF2 PF05812.7 AJW69755.1 - 0.16 11.8 3.1 0.27 11.0 2.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF1515 PF07439.6 AJW69755.1 - 0.17 11.6 1.0 5.6 6.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF1664 PF07889.7 AJW69755.1 - 0.18 11.6 3.6 0.24 11.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tnp_P_element PF12017.3 AJW69755.1 - 0.19 10.9 3.3 0.27 10.4 2.3 1.2 1 0 0 1 1 1 0 Transposase protein Rootletin PF15035.1 AJW69755.1 - 0.2 11.5 4.9 0.27 11.1 3.4 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GrpE PF01025.14 AJW69755.1 - 0.21 11.1 3.0 0.31 10.5 2.1 1.3 1 0 0 1 1 1 0 GrpE TPR_MLP1_2 PF07926.7 AJW69755.1 - 0.21 11.3 6.7 0.37 10.5 0.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 AJW69755.1 - 0.22 11.3 2.7 6 6.9 0.1 3.4 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Img2 PF05046.9 AJW69755.1 - 0.22 11.7 1.4 0.3 11.3 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) FemAB PF02388.11 AJW69755.1 - 0.23 10.0 2.9 0.28 9.8 2.0 1.1 1 0 0 1 1 1 0 FemAB family DUF4407 PF14362.1 AJW69755.1 - 0.26 10.2 1.7 0.39 9.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GLE1 PF07817.8 AJW69755.1 - 0.27 10.1 2.8 0.34 9.8 1.9 1.1 1 0 0 1 1 1 0 GLE1-like protein Snapin_Pallidin PF14712.1 AJW69755.1 - 0.29 11.4 5.2 0.36 11.1 2.4 1.8 1 1 1 2 2 2 0 Snapin/Pallidin CtIP_N PF10482.4 AJW69755.1 - 0.29 10.9 5.0 0.76 9.5 3.5 1.6 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2935 PF11155.3 AJW69755.1 - 0.31 11.1 2.4 0.41 10.7 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Trypan_PARP PF05887.6 AJW69755.1 - 0.32 10.8 16.9 0.46 10.2 11.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NPV_P10 PF05531.7 AJW69755.1 - 0.32 11.2 4.8 0.69 10.2 3.3 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF713 PF05218.9 AJW69755.1 - 0.36 10.5 4.7 0.89 9.2 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF713) DASH_Dam1 PF08653.5 AJW69755.1 - 0.4 10.4 2.4 6.1 6.6 0.2 2.3 1 1 1 2 2 2 0 DASH complex subunit Dam1 Flagellin_C PF00700.16 AJW69755.1 - 0.44 10.7 4.6 2.3 8.4 0.2 2.1 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DUF4315 PF14193.1 AJW69755.1 - 0.45 10.4 6.1 0.82 9.6 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) Ax_dynein_light PF10211.4 AJW69755.1 - 0.48 10.2 5.6 0.76 9.5 3.9 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain TBCA PF02970.11 AJW69755.1 - 0.49 10.5 4.9 0.78 9.8 3.0 1.6 1 1 1 2 2 2 0 Tubulin binding cofactor A Mnd1 PF03962.10 AJW69755.1 - 0.51 9.9 4.9 1.1 8.9 3.4 1.5 1 1 0 1 1 1 0 Mnd1 family Cep57_CLD_2 PF14197.1 AJW69755.1 - 0.55 10.2 4.8 0.73 9.8 2.8 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Rho_Binding PF08912.6 AJW69755.1 - 0.74 10.1 7.3 0.16 12.2 0.7 2.2 1 1 1 2 2 2 0 Rho Binding ORF6C PF10552.4 AJW69755.1 - 0.74 9.5 4.8 1.1 9.0 2.2 1.8 1 1 1 2 2 2 0 ORF6C domain Mei5 PF10376.4 AJW69755.1 - 0.8 9.1 7.9 0.18 11.2 1.0 1.8 1 1 0 1 1 1 0 Double-strand recombination repair protein DUF3373 PF11853.3 AJW69755.1 - 0.82 8.1 3.3 0.99 7.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Kinetocho_Slk19 PF12709.2 AJW69755.1 - 1 9.4 4.5 1.5 8.9 2.5 1.7 1 1 1 2 2 2 0 Central kinetochore-associated Fzo_mitofusin PF04799.8 AJW69755.1 - 1 8.6 5.6 4.4 6.6 3.9 1.8 1 1 0 1 1 1 0 fzo-like conserved region DUF2312 PF10073.4 AJW69755.1 - 1.5 8.2 5.6 2.1 7.7 0.4 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Fib_alpha PF08702.5 AJW69755.1 - 1.6 8.8 6.0 3.9 7.5 4.1 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3530 PF12048.3 AJW69755.1 - 1.6 7.6 6.4 1.1 8.2 2.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) AKNA PF12443.3 AJW69755.1 - 3.1 7.8 6.4 14 5.7 0.2 2.6 2 1 1 3 3 2 0 AT-hook-containing transcription factor PspB PF06667.7 AJW69755.1 - 3.5 7.6 4.9 5.5 6.9 0.5 2.6 1 1 1 2 2 2 0 Phage shock protein B DUF3847 PF12958.2 AJW69755.1 - 3.9 7.2 8.2 4.8 7.0 2.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) SlyX PF04102.7 AJW69755.1 - 7 7.1 11.5 3.6 8.0 1.9 2.6 2 1 1 3 3 2 0 SlyX Evr1_Alr PF04777.8 AJW69756.1 - 0.0021 17.9 0.1 0.0021 17.9 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Pox_vIL-18BP PF05566.7 AJW69756.1 - 0.062 13.2 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein dCMP_cyt_deam_1 PF00383.17 AJW69756.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region AAA PF00004.24 AJW69757.1 - 6.1e-100 330.6 0.0 5.7e-50 168.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AJW69757.1 - 4.8e-21 74.5 0.1 1.4e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AJW69757.1 - 2.4e-17 63.3 0.3 5.5e-08 32.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AJW69757.1 - 2.6e-14 52.8 0.0 6e-08 32.0 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AJW69757.1 - 5.2e-14 52.1 1.1 5.7e-06 26.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 AJW69757.1 - 7.1e-14 52.6 0.0 2.6e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AJW69757.1 - 1.1e-13 51.6 0.0 2.4e-06 27.6 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AJW69757.1 - 1.8e-12 47.5 1.8 0.00099 19.2 0.2 4.4 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 AJW69757.1 - 7.6e-12 44.6 0.7 1.9e-11 43.3 0.5 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 AJW69757.1 - 1.4e-11 44.3 0.0 5.7e-05 23.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 AJW69757.1 - 4.5e-11 42.2 0.0 0.00027 20.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 AJW69757.1 - 1.7e-10 40.1 0.1 0.00026 19.8 0.0 2.8 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 AJW69757.1 - 2.4e-10 40.4 0.0 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AJW69757.1 - 4.5e-09 36.6 0.1 0.00027 21.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AJW69757.1 - 6.3e-09 35.4 0.1 0.0031 16.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 AJW69757.1 - 6.8e-09 35.3 1.8 0.0026 17.4 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 AJW69757.1 - 8e-08 31.6 0.2 0.011 14.8 0.0 2.8 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AJW69757.1 - 2.9e-07 30.1 0.3 0.12 11.8 0.0 4.1 2 2 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 AJW69757.1 - 9.8e-07 28.9 0.0 0.055 13.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.6 AJW69757.1 - 2.7e-06 27.0 0.0 0.024 14.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AJW69757.1 - 3.3e-06 27.1 0.1 0.091 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 AJW69757.1 - 5.3e-06 26.7 0.4 0.17 12.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_25 PF13481.1 AJW69757.1 - 1e-05 25.0 6.5 0.22 10.8 0.6 4.3 2 2 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 AJW69757.1 - 1.9e-05 24.7 0.0 0.19 11.7 0.0 3.0 3 0 0 3 3 2 2 Sigma-54 interaction domain NACHT PF05729.7 AJW69757.1 - 2.5e-05 23.9 1.0 1.5 8.4 0.0 4.1 3 1 1 4 4 4 1 NACHT domain PhoH PF02562.11 AJW69757.1 - 3.3e-05 23.2 0.3 0.29 10.3 0.1 2.7 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.8 AJW69757.1 - 4.2e-05 22.5 0.0 0.2 10.5 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.1 AJW69757.1 - 5.8e-05 22.7 0.0 0.085 12.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.1 AJW69757.1 - 6.7e-05 22.5 2.8 0.025 14.1 0.3 3.1 2 1 1 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 AJW69757.1 - 7.5e-05 21.7 0.3 0.16 10.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 AJW69757.1 - 0.00017 21.4 0.2 0.064 13.0 0.0 3.2 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 AJW69757.1 - 0.00017 21.2 0.1 0.16 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 AJW69757.1 - 0.00024 20.9 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase DUF2075 PF09848.4 AJW69757.1 - 0.00035 19.6 0.1 0.45 9.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 AJW69757.1 - 0.00036 20.3 0.2 0.06 13.0 0.0 3.4 2 2 1 3 3 3 1 Archaeal ATPase NTPase_1 PF03266.10 AJW69757.1 - 0.00044 20.0 1.6 1.6 8.4 0.0 4.0 2 1 1 3 3 3 1 NTPase NB-ARC PF00931.17 AJW69757.1 - 0.00076 18.4 0.1 0.82 8.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain T2SE PF00437.15 AJW69757.1 - 0.00095 18.1 0.0 0.95 8.3 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein KaiC PF06745.8 AJW69757.1 - 0.0013 17.8 4.7 0.62 9.1 0.0 4.0 3 1 1 4 4 4 1 KaiC UPF0079 PF02367.12 AJW69757.1 - 0.0025 17.4 1.5 1.7 8.3 0.1 3.1 2 1 1 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 AJW69757.1 - 0.0037 16.7 0.0 0.68 9.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 AJW69757.1 - 0.0052 16.4 0.1 0.24 11.0 0.0 2.7 2 1 0 3 3 2 1 Chloramphenicol phosphotransferase-like protein Vps4_C PF09336.5 AJW69757.1 - 0.01 15.7 0.7 0.39 10.6 0.1 3.0 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.13 AJW69757.1 - 0.011 15.3 0.0 1.2 8.7 0.0 3.0 2 1 0 2 2 2 0 Bacterial dnaA protein Viral_helicase1 PF01443.13 AJW69757.1 - 0.014 14.8 0.0 0.16 11.4 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 AJW69757.1 - 0.022 13.4 0.2 3.7 6.1 0.0 2.9 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein PIF1 PF05970.9 AJW69757.1 - 0.025 13.5 0.0 1.8 7.4 0.0 2.6 2 0 0 2 2 2 0 PIF1-like helicase UFD1 PF03152.9 AJW69757.1 - 0.033 13.3 1.0 0.056 12.5 0.1 1.8 2 0 0 2 2 1 0 Ubiquitin fusion degradation protein UFD1 IPT PF01745.11 AJW69757.1 - 0.035 13.2 0.4 5.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.6 AJW69757.1 - 0.041 13.7 0.1 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Torsin KTI12 PF08433.5 AJW69757.1 - 0.041 13.0 2.6 2.3 7.3 0.0 3.4 5 0 0 5 5 3 0 Chromatin associated protein KTI12 AFG1_ATPase PF03969.11 AJW69757.1 - 0.073 11.8 0.0 9.9 4.8 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase DUF2443 PF10398.4 AJW69757.1 - 0.14 12.0 3.4 0.23 11.3 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2443) PPV_E1_C PF00519.12 AJW69757.1 - 0.14 10.7 0.0 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase HSP20 PF00011.16 AJW69758.1 - 1.4e-07 31.2 6.7 1.9e-06 27.6 4.7 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 AJW69758.1 - 0.003 17.0 0.2 0.0036 16.7 0.1 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 AJW69758.1 - 0.012 16.1 2.9 0.019 15.5 2.0 1.2 1 0 0 1 1 1 0 CS domain HMA PF00403.21 AJW69758.1 - 0.4 10.8 3.9 0.71 10.0 2.7 1.4 1 0 0 1 1 1 0 Heavy-metal-associated domain ACT_7 PF13840.1 AJW69759.1 - 2.8e-08 33.1 0.2 5.5e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 ACT domain SecD-TM1 PF13721.1 AJW69759.1 - 0.016 15.4 0.1 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 SecD export protein N-terminal TM region DapH_N PF08503.5 AJW69759.1 - 0.75 9.9 3.4 0.52 10.4 0.1 2.3 3 0 0 3 3 3 0 Tetrahydrodipicolinate succinyltransferase N-terminal Pyr_redox_2 PF07992.9 AJW69760.1 - 1.3e-19 70.9 0.0 4.8e-19 69.0 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJW69760.1 - 2.2e-16 59.9 0.3 3.3e-11 43.4 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJW69760.1 - 5.6e-05 22.2 1.0 2.1 7.1 0.0 4.0 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AJW69760.1 - 6e-05 23.2 0.0 0.0044 17.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AJW69760.1 - 0.0022 17.7 0.3 5.2 6.8 0.0 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding GIDA PF01134.17 AJW69760.1 - 0.046 12.5 0.3 5.6 5.7 0.3 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AJW69760.1 - 0.052 13.5 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AJW69760.1 - 0.11 11.1 0.0 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 AJW69760.1 - 0.12 11.2 0.0 14 4.4 0.0 2.7 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 AJW69760.1 - 0.15 10.8 0.4 18 4.0 0.0 3.0 3 0 0 3 3 3 0 FAD binding domain Pro_isomerase PF00160.16 AJW69761.1 - 9e-45 152.6 0.1 1.5e-44 151.9 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbP PF01789.11 AJW69761.1 - 0.016 14.6 0.0 0.055 12.9 0.0 1.9 1 1 0 1 1 1 0 PsbP bPH_3 PF14470.1 AJW69762.1 - 0.00022 21.4 0.7 0.036 14.3 0.0 2.6 3 0 0 3 3 3 2 Bacterial PH domain TP_methylase PF00590.15 AJW69763.1 - 4.7e-35 121.2 0.0 5.3e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases GcpE PF04551.9 AJW69763.1 - 0.11 11.2 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 GcpE protein Copper-bind PF00127.15 AJW69764.1 - 1.5e-05 25.1 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family tRNA_anti-codon PF01336.20 AJW69764.1 - 0.092 12.6 0.3 9.3 6.1 0.1 2.9 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain DUF95 PF01944.12 AJW69765.1 - 4.5e-08 32.9 16.6 5.8e-08 32.5 11.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF95 DNA_pol_E_B PF04042.11 AJW69766.1 - 7.2e-23 80.9 0.0 1.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 AJW69766.1 - 5e-11 42.6 0.0 9.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AJW69766.1 - 8.4e-07 28.5 0.1 2.1e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2326 PF10088.4 AJW69766.1 - 0.038 13.5 0.8 0.089 12.4 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) Cdc6_C PF09079.6 AJW69767.1 - 2.8e-19 68.6 0.4 7.6e-19 67.2 0.3 1.7 1 0 0 1 1 1 1 CDC6, C terminal AAA_22 PF13401.1 AJW69767.1 - 3.2e-13 49.9 0.5 8.6e-13 48.5 0.0 1.9 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.1 AJW69767.1 - 2.6e-11 43.8 0.5 1.6e-10 41.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AJW69767.1 - 3.4e-10 40.2 0.1 1.4e-09 38.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AJW69767.1 - 2.9e-07 30.2 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 AJW69767.1 - 1.4e-06 28.1 1.7 1.4e-06 28.1 1.2 2.3 2 1 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 AJW69767.1 - 0.00012 21.0 0.0 0.00025 20.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.9 AJW69767.1 - 0.00069 19.3 0.2 0.0028 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 AJW69767.1 - 0.00084 18.4 0.1 0.001 18.1 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AJW69767.1 - 0.0024 17.5 0.0 0.0079 15.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 AJW69767.1 - 0.0029 16.3 0.0 0.0076 14.9 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 AJW69767.1 - 0.0046 17.1 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_32 PF13654.1 AJW69767.1 - 0.0064 15.2 0.5 0.16 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.9 AJW69767.1 - 0.0067 15.4 0.0 0.03 13.2 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase AAA_24 PF13479.1 AJW69767.1 - 0.013 15.1 0.0 0.037 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 AJW69767.1 - 0.014 14.4 0.1 2.8 6.8 0.0 2.6 2 1 0 3 3 3 0 KAP family P-loop domain DUF815 PF05673.8 AJW69767.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SE PF00437.15 AJW69767.1 - 0.016 14.0 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 AJW69767.1 - 0.019 14.8 0.0 0.068 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 AJW69767.1 - 0.019 14.2 0.1 0.31 10.2 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.10 AJW69767.1 - 0.021 14.5 0.3 0.26 10.9 0.2 2.5 1 1 0 1 1 1 0 NTPase KaiC PF06745.8 AJW69767.1 - 0.024 13.7 0.7 0.48 9.5 0.1 2.7 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.16 AJW69767.1 - 0.031 13.4 0.0 0.09 11.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 AJW69767.1 - 0.034 13.7 2.0 0.11 12.0 1.3 1.9 1 1 0 1 1 1 0 AAA domain DUF512 PF04459.7 AJW69767.1 - 0.038 13.0 0.9 0.39 9.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF512) Sigma54_activat PF00158.21 AJW69767.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.6 AJW69767.1 - 0.081 12.8 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Torsin T2SF PF00482.18 AJW69767.1 - 0.17 11.8 0.7 2.1 8.2 0.1 2.6 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Penicillinase_R PF03965.11 AJW69768.1 - 0.0045 17.0 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Penicillinase repressor Antitoxin-MazE PF04014.13 AJW69769.1 - 5.2e-07 29.2 0.1 6.2e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Antidote-toxin recognition MazE MraZ PF02381.13 AJW69769.1 - 0.08 12.7 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 MraZ protein eIF-1a PF01176.14 AJW69769.1 - 0.086 12.2 0.1 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 HTH_27 PF13463.1 AJW69770.1 - 1.4e-06 28.5 0.1 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 AJW69770.1 - 2.7e-06 27.0 0.1 6.4e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 AJW69770.1 - 0.00071 19.5 0.2 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 AJW69770.1 - 0.0017 18.0 0.1 0.0046 16.6 0.1 1.8 1 0 0 1 1 1 1 MarR family DUF3116 PF11313.3 AJW69770.1 - 0.0058 16.2 0.2 0.019 14.5 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3116) Replic_Relax PF13814.1 AJW69770.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Replication-relaxation HTH_45 PF14947.1 AJW69770.1 - 0.012 15.4 0.7 0.023 14.5 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix HTH_24 PF13412.1 AJW69770.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AJW69770.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 AJW69770.1 - 0.17 12.0 0.4 2.2 8.4 0.0 2.4 2 1 1 3 3 3 0 Transcriptional regulator DUF4163 PF13739.1 AJW69770.1 - 0.83 10.4 3.4 0.58 10.9 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) FliH PF02108.11 AJW69771.1 - 0.078 12.8 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Flagellar assembly protein FliH PcrB PF01884.12 AJW69772.1 - 3e-65 219.7 0.2 3.5e-65 219.5 0.2 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.16 AJW69772.1 - 7.2e-08 31.9 0.2 6.7e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.20 AJW69772.1 - 3.9e-06 26.0 0.3 1.9e-05 23.7 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain B12-binding PF02310.14 AJW69772.1 - 0.00074 19.3 0.6 1.4 8.7 0.0 3.6 3 1 0 3 3 3 1 B12 binding domain Trp_syntA PF00290.15 AJW69772.1 - 0.0026 16.3 1.5 0.015 13.8 0.1 2.3 2 1 1 3 3 3 1 Tryptophan synthase alpha chain ThiG PF05690.9 AJW69772.1 - 0.01 14.9 1.0 1 8.3 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IGPS PF00218.16 AJW69772.1 - 0.01 14.9 0.2 0.24 10.4 0.0 2.4 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase NanE PF04131.9 AJW69772.1 - 0.012 14.6 1.9 0.43 9.5 0.1 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase BtpA PF03437.10 AJW69772.1 - 0.012 14.9 1.3 0.58 9.3 0.1 2.2 2 0 0 2 2 2 0 BtpA family Ribul_P_3_epim PF00834.14 AJW69772.1 - 0.016 14.2 0.2 0.066 12.3 0.1 1.9 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 AJW69772.1 - 0.073 12.1 0.1 0.87 8.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Dus PF01207.12 AJW69772.1 - 0.076 11.8 0.1 0.5 9.1 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DeoC PF01791.4 AJW69772.1 - 0.082 12.1 0.4 0.27 10.5 0.1 1.8 2 0 0 2 2 2 0 DeoC/LacD family aldolase Peripla_BP_1 PF00532.16 AJW69772.1 - 0.1 11.8 0.2 0.42 9.7 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family PolC_DP2 PF03833.8 AJW69773.1 - 2.5e-265 882.5 0.2 1.1e-264 880.4 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase II large subunit DP2 DUF2296 PF10058.4 AJW69773.1 - 2.4 7.9 7.7 2 8.2 2.7 2.6 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-B_box PF00643.19 AJW69773.1 - 5.1 7.0 15.7 7.2 6.6 7.4 2.9 2 1 0 2 2 2 0 B-box zinc finger SHMT PF00464.14 AJW69774.1 - 7.7e-76 255.0 0.0 1e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 AJW69774.1 - 5.3e-07 28.9 0.1 2.6e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AJW69774.1 - 1.4e-06 27.6 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 AJW69774.1 - 0.00012 20.9 0.0 0.00021 20.1 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_5 PF00266.14 AJW69774.1 - 0.00075 18.3 0.2 0.0027 16.4 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 AJW69774.1 - 0.021 13.2 0.0 0.031 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cpn60_TCP1 PF00118.19 AJW69775.1 - 6.5e-167 556.0 16.8 7.4e-167 555.8 11.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF240 PF03086.9 AJW69775.1 - 0.082 12.5 1.1 2.3 7.8 0.4 2.5 2 0 0 2 2 2 0 MG032/MG096/MG288 family 2 Ustilago_mating PF05722.7 AJW69775.1 - 0.083 12.1 0.2 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Ustilago B locus mating-type protein Ribosomal_L22 PF00237.14 AJW69775.1 - 0.29 11.0 4.1 27 4.7 1.7 3.0 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e Bax1-I PF01027.15 AJW69776.1 - 0.091 12.3 8.5 0.09 12.3 5.9 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 RseC_MucC PF04246.7 AJW69776.1 - 1.6 8.2 4.4 0.93 9.0 1.9 1.4 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC RDD PF06271.7 AJW69776.1 - 2.6 7.9 6.7 8.8 6.2 4.2 1.8 1 1 1 2 2 2 0 RDD family Gln-synt_C PF00120.19 AJW69777.1 - 9.3e-88 293.7 0.0 1.2e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AJW69777.1 - 9e-26 89.2 0.0 1.8e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Peptidase_A3 PF02160.10 AJW69778.1 - 0.025 14.1 1.0 0.04 13.5 0.6 1.5 1 1 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) CLN6 PF15156.1 AJW69779.1 - 0.011 14.8 0.6 0.012 14.7 0.4 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 EmrE PF13536.1 AJW69779.1 - 0.013 15.6 4.9 0.018 15.2 3.4 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter B12D PF06522.6 AJW69779.1 - 0.052 13.2 0.4 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-AN1 PF01428.11 AJW69780.1 - 4e-13 49.0 6.0 5.1e-13 48.6 4.2 1.1 1 0 0 1 1 1 1 AN1-like Zinc finger UPF1_Zn_bind PF09416.5 AJW69780.1 - 0.1 12.1 1.3 0.11 12.0 0.9 1.2 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) RecR PF02132.10 AJW69780.1 - 0.21 11.0 2.3 0.41 10.1 1.6 1.4 1 0 0 1 1 1 0 RecR protein adh_short PF00106.20 AJW69781.1 - 2.7e-37 128.2 0.2 3.7e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AJW69781.1 - 1.2e-19 71.0 0.5 1.6e-19 70.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AJW69781.1 - 1.3e-13 51.0 0.1 1.7e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AJW69781.1 - 4.7e-05 23.4 0.9 0.00012 22.1 0.6 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AJW69781.1 - 0.00059 19.3 0.1 0.014 14.8 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AJW69781.1 - 0.0028 17.3 1.4 0.01 15.6 1.0 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TPM PF04536.9 AJW69781.1 - 0.092 12.6 0.1 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Pyr_redox_2 PF07992.9 AJW69782.1 - 3.9e-22 79.1 0.0 7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJW69782.1 - 4.4e-07 30.2 0.9 0.0018 18.6 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AJW69782.1 - 0.00035 20.5 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AJW69782.1 - 0.00074 18.5 0.0 0.01 14.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AJW69782.1 - 0.0011 18.7 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 AJW69782.1 - 0.0042 15.7 0.0 0.006 15.2 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.19 AJW69782.1 - 0.053 12.3 0.0 0.28 9.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 AJW69782.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 AJW69782.1 - 0.12 11.2 0.0 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pkinase PF00069.20 AJW69784.1 - 2.6e-05 23.4 1.4 2.6e-05 23.4 1.0 1.8 1 1 1 2 2 2 1 Protein kinase domain RIO1 PF01163.17 AJW69784.1 - 5.1e-05 22.6 1.3 6.2e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 AJW69784.1 - 0.00035 20.2 0.4 0.0019 17.8 0.3 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 AJW69784.1 - 0.057 12.4 6.2 0.03 13.3 0.6 2.1 1 1 0 2 2 2 0 Protein tyrosine kinase Cofilin_ADF PF00241.15 AJW69784.1 - 0.087 12.7 3.5 0.53 10.1 0.9 2.4 1 1 1 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein tRNA_NucTransf2 PF09249.6 AJW69785.1 - 1.2e-37 128.2 0.2 2.7e-37 127.1 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.18 AJW69785.1 - 8.6e-10 38.8 1.5 1.7e-09 37.9 0.4 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain DZF PF07528.9 AJW69785.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 DZF domain LigT_PEase PF02834.11 AJW69786.1 - 2.9e-27 94.4 0.0 2.6e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.4 AJW69786.1 - 2.6e-14 53.4 0.0 4.5e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 AJW69786.1 - 4.7e-09 36.1 0.0 5.4e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily HVSL PF09749.4 AJW69786.1 - 0.0082 15.1 0.0 0.061 12.3 0.0 1.9 1 1 1 2 2 2 1 Uncharacterised conserved protein Decorin_bind PF02352.10 AJW69786.1 - 0.044 13.7 0.2 3.5 7.6 0.1 2.6 2 0 0 2 2 2 0 Decorin binding protein AAA_18 PF13238.1 AJW69787.1 - 8.7e-15 55.1 0.1 1.2e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJW69787.1 - 3.3e-11 44.0 0.0 4.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AJW69787.1 - 6.3e-05 22.8 0.1 0.00019 21.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AJW69787.1 - 0.00037 20.4 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 AJW69787.1 - 0.0005 19.7 0.1 0.0047 16.5 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase CoaE PF01121.15 AJW69787.1 - 0.0019 17.6 0.0 0.0056 16.1 0.0 1.7 1 1 1 2 2 2 1 Dephospho-CoA kinase AAA_22 PF13401.1 AJW69787.1 - 0.0021 18.1 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 AJW69787.1 - 0.0053 15.5 0.1 0.0087 14.8 0.1 1.3 1 0 0 1 1 1 1 ArgK protein AAA PF00004.24 AJW69787.1 - 0.012 15.8 0.2 0.024 14.8 0.1 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ADK PF00406.17 AJW69787.1 - 0.02 14.7 0.2 0.027 14.3 0.1 1.3 1 1 0 1 1 1 0 Adenylate kinase KTI12 PF08433.5 AJW69787.1 - 0.023 13.8 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 AJW69787.1 - 0.03 14.2 0.3 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family Zeta_toxin PF06414.7 AJW69787.1 - 0.035 13.1 0.1 0.065 12.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 AJW69787.1 - 0.037 13.7 0.3 0.14 11.8 0.2 1.9 1 1 1 2 2 2 0 NTPase AAA_14 PF13173.1 AJW69787.1 - 0.048 13.5 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AJW69787.1 - 0.057 13.7 0.4 0.066 13.5 0.3 1.3 1 1 0 1 1 1 0 ABC transporter ATP_bind_2 PF03668.10 AJW69787.1 - 0.073 12.1 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family NB-ARC PF00931.17 AJW69787.1 - 0.075 11.8 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 AJW69787.1 - 0.077 12.7 0.2 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 AJW69787.1 - 0.082 13.2 1.0 0.12 12.6 0.7 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AJW69787.1 - 0.092 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 AJW69787.1 - 0.12 12.3 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain RNA_binding PF01877.12 AJW69788.1 - 3.2e-18 65.8 0.0 7.3e-18 64.7 0.0 1.5 1 1 0 1 1 1 1 RNA binding Mer2 PF09074.5 AJW69789.1 - 0.013 15.4 2.9 0.017 15.0 2.0 1.4 1 0 0 1 1 1 0 Mer2 ISG65-75 PF11727.3 AJW69789.1 - 0.019 14.0 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein MT0933_antitox PF14013.1 AJW69789.1 - 0.15 12.1 0.3 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 MT0933-like antitoxin protein HN PF00423.14 AJW69789.1 - 0.66 8.1 12.5 0.76 7.9 8.7 1.0 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase SIR2 PF02146.12 AJW69790.1 - 5.9e-55 185.7 0.0 7.6e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family RNA_POL_M_15KD PF02150.11 AJW69790.1 - 0.018 14.6 1.4 0.14 11.8 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Lactamase_B_2 PF12706.2 AJW69791.1 - 7.1e-26 90.9 0.0 9.5e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AJW69791.1 - 8.7e-07 28.7 0.0 5.5e-06 26.1 0.0 2.1 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily UPF0020 PF01170.13 AJW69792.1 - 8.5e-26 90.6 0.0 1.5e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AJW69792.1 - 3.1e-14 53.0 0.0 4.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 AJW69792.1 - 4e-13 49.3 0.0 3.7e-12 46.2 0.0 2.1 2 1 0 2 2 2 1 DNA methylase Methyltransf_31 PF13847.1 AJW69792.1 - 4e-11 42.7 0.1 8.8e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 AJW69792.1 - 2.5e-05 23.7 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.11 AJW69792.1 - 7.1e-05 22.0 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 AJW69792.1 - 9.2e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW69792.1 - 0.00038 21.0 0.0 0.00069 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJW69792.1 - 0.00043 19.7 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 AJW69792.1 - 0.00092 18.8 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 AJW69792.1 - 0.0016 17.6 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) THUMP PF02926.12 AJW69792.1 - 0.002 18.0 0.5 0.0082 16.0 0.1 2.2 2 1 0 2 2 1 1 THUMP domain Methyltransf_5 PF01795.14 AJW69792.1 - 0.0045 16.2 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family CMAS PF02353.15 AJW69792.1 - 0.0082 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MethyltransfD12 PF02086.10 AJW69792.1 - 0.0088 15.5 0.1 0.019 14.4 0.0 1.8 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_11 PF08241.7 AJW69792.1 - 0.01 16.3 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 AJW69792.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF718 PF05336.8 AJW69792.1 - 0.015 15.1 0.1 7 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF718) Pribosyltran_N PF13793.1 AJW69793.1 - 1.5e-25 89.1 0.6 1.3e-24 86.1 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AJW69793.1 - 2.1e-13 50.4 3.8 6.2e-13 48.8 0.5 2.8 2 2 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AJW69793.1 - 3.7e-12 46.0 2.0 9.9e-12 44.6 0.0 2.6 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AJW69793.1 - 0.00033 19.9 0.0 0.0006 19.0 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 AJW69793.1 - 0.0019 17.5 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase MS_channel PF00924.13 AJW69794.1 - 8e-32 110.2 0.4 1.4e-31 109.4 0.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel O-ag_pol_Wzy PF14296.1 AJW69794.1 - 0.09 11.3 5.9 0.41 9.1 3.6 1.9 1 1 1 2 2 2 0 O-antigen polysaccharide polymerase Wzy DUF1129 PF06570.6 AJW69794.1 - 0.87 8.8 5.6 0.17 11.1 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PepSY_TM_2 PF13703.1 AJW69794.1 - 5 7.3 6.9 0.89 9.7 0.8 2.2 2 0 0 2 2 2 0 PepSY-associated TM helix Fer4_14 PF13394.1 AJW69795.1 - 5.6e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 AJW69795.1 - 4.4e-05 23.7 0.2 0.00082 19.5 0.1 2.6 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 AJW69795.1 - 0.0002 21.4 0.2 0.0004 20.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain RVT_connect PF06815.8 AJW69795.1 - 0.054 13.3 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase connection domain AA_permease_2 PF13520.1 AJW69797.1 - 7.1e-47 159.8 60.7 9e-47 159.5 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AJW69797.1 - 5.7e-41 140.3 57.0 8.4e-41 139.8 39.5 1.3 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 AJW69797.1 - 2.5e-06 26.3 26.7 2.5e-06 26.3 18.5 2.6 1 1 0 2 2 2 1 Spore germination protein AA_permease_C PF13906.1 AJW69797.1 - 0.076 12.8 0.4 0.076 12.8 0.3 4.7 6 0 0 6 6 6 0 C-terminus of AA_permease VIT1 PF01988.14 AJW69798.1 - 1.2e-62 211.1 2.0 1.3e-62 211.0 1.4 1.0 1 0 0 1 1 1 1 VIT family PGG PF13962.1 AJW69798.1 - 0.022 14.3 4.2 0.058 13.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function Usp PF00582.21 AJW69799.1 - 1.4e-27 96.6 0.0 1.7e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family TGT PF01702.13 AJW69799.1 - 0.084 12.1 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase DnaJ PF00226.26 AJW69800.1 - 4.1e-11 42.4 0.1 9.1e-11 41.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Aha1_N PF09229.6 AJW69800.1 - 0.01 15.6 1.2 0.23 11.2 0.1 2.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal Urease_alpha PF00449.15 AJW69800.1 - 0.032 14.3 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain KIAA1430 PF13879.1 AJW69800.1 - 0.043 14.2 0.3 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 KIAA1430 homologue DUF4098 PF13345.1 AJW69800.1 - 0.045 13.7 0.9 2.8 7.9 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4098) HAMP PF00672.20 AJW69801.1 - 3.8e-18 65.4 0.1 3.9e-17 62.1 0.0 2.3 2 0 0 2 2 2 1 HAMP domain Guanylate_cyc PF00211.15 AJW69801.1 - 2.5e-15 56.3 0.2 5.6e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Copper-bind PF00127.15 AJW69802.1 - 1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Slp PF03843.8 AJW69802.1 - 0.0063 15.5 0.1 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 Outer membrane lipoprotein Slp family Fer4 PF00037.22 AJW69803.1 - 1.7e-11 43.2 10.5 4.3e-07 29.2 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AJW69803.1 - 1e-09 38.6 3.7 1.5e-09 38.1 2.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJW69803.1 - 1.6e-09 37.2 8.6 3.7e-05 23.4 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AJW69803.1 - 9.5e-08 31.7 3.3 1.6e-07 31.0 2.3 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJW69803.1 - 9.7e-08 31.7 1.6 1.4e-07 31.2 1.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJW69803.1 - 2.6e-07 30.1 8.9 0.0032 17.2 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AJW69803.1 - 1.6e-05 25.0 8.2 0.00017 21.7 5.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 AJW69803.1 - 1.8e-05 24.7 7.8 0.03 14.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 AJW69803.1 - 6.3e-05 23.6 1.0 0.17 12.6 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 AJW69803.1 - 7.7e-05 22.9 12.3 0.043 14.3 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AJW69803.1 - 8.6e-05 22.8 5.2 0.14 12.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_8 PF13183.1 AJW69803.1 - 0.0002 21.3 3.9 0.00055 19.9 2.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 AJW69803.1 - 0.00024 21.5 9.6 0.012 16.1 0.7 2.7 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 AJW69803.1 - 0.00057 20.2 6.2 0.041 14.3 1.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AJW69803.1 - 0.0026 18.0 5.6 0.056 13.7 3.8 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Aminotran_5 PF00266.14 AJW69804.1 - 2.2e-68 230.6 0.0 2.5e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AJW69804.1 - 6.8e-09 35.1 0.0 1.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II YgbB PF02542.11 AJW69804.1 - 0.0081 15.9 0.1 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 YgbB family Beta_elim_lyase PF01212.16 AJW69804.1 - 0.013 14.6 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AsnC_trans_reg PF01037.16 AJW69805.1 - 7.3e-08 32.0 0.2 8.1e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 AsnC family phage_tail_N PF08400.5 AJW69805.1 - 0.081 12.6 0.2 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Cyclase PF04199.8 AJW69806.1 - 3.3e-34 118.0 0.0 4.4e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase DSPc PF00782.15 AJW69807.1 - 4.7e-17 61.8 0.0 6.1e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AJW69807.1 - 4.2e-09 36.1 0.1 1.7e-08 34.0 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AJW69807.1 - 1.6e-06 28.2 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 AJW69807.1 - 0.00085 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 AJW69807.1 - 0.0073 16.5 0.1 0.021 15.0 0.1 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 AJW69807.1 - 0.01 15.2 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family RNA_pol_L_2 PF13656.1 AJW69811.1 - 6.8e-18 63.8 0.1 7.9e-18 63.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TFIIS_C PF01096.13 AJW69812.1 - 3e-19 68.3 6.7 3e-19 68.3 4.7 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 AJW69812.1 - 6.5e-06 25.8 6.3 0.0033 17.1 0.9 2.3 2 0 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.11 AJW69812.1 - 0.00048 19.7 14.1 0.042 13.5 4.1 4.1 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 AJW69812.1 - 0.003 17.2 5.2 0.15 11.7 0.1 2.2 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 AJW69812.1 - 0.0049 16.3 14.1 0.017 14.5 2.8 3.5 3 1 0 3 3 3 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AJW69812.1 - 0.0095 15.7 13.0 0.021 14.6 1.2 3.1 2 1 1 3 3 3 1 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 AJW69812.1 - 0.011 15.1 3.8 0.012 14.9 0.1 2.2 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger zinc-ribbons_6 PF07191.7 AJW69812.1 - 0.042 13.6 6.0 0.062 13.0 0.4 2.8 3 0 0 3 3 3 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 AJW69812.1 - 0.12 12.0 13.9 0.51 10.0 1.4 3.0 2 2 1 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.1 AJW69812.1 - 0.16 11.6 15.4 3.5 7.3 0.4 4.2 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AJW69812.1 - 0.26 11.2 16.9 1.5 8.8 0.0 4.2 3 1 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 AJW69812.1 - 0.29 10.7 15.5 4.1 7.0 0.4 4.2 3 1 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.1 AJW69812.1 - 0.48 10.1 9.3 0.16 11.7 1.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-Mss51 PF13824.1 AJW69812.1 - 1 9.2 7.4 0.78 9.6 0.1 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 AJW69812.1 - 1.2 9.0 9.9 1 9.3 0.6 2.5 2 0 0 2 2 2 0 MYND finger Cytochrom_CIII PF02085.11 AJW69812.1 - 1.3 9.1 7.3 10 6.2 1.0 2.4 1 1 0 2 2 2 0 Class III cytochrome C family C1_4 PF07975.7 AJW69812.1 - 1.3 9.0 9.1 1.6 8.7 0.1 3.2 3 1 0 3 3 3 0 TFIIH C1-like domain DUF3795 PF12675.2 AJW69812.1 - 1.5 9.0 10.4 0.37 11.0 4.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Ribosomal_L44 PF00935.14 AJW69812.1 - 1.5 8.8 15.8 5.6 7.0 2.2 3.2 2 1 1 3 3 3 0 Ribosomal protein L44 zf-ribbon_3 PF13248.1 AJW69812.1 - 1.6 8.0 14.8 1.6 8.0 0.6 3.8 3 1 0 4 4 4 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AJW69812.1 - 1.9 8.0 11.8 13 5.3 0.0 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain C1_1 PF00130.17 AJW69812.1 - 2.1 8.1 14.6 0.22 11.2 1.8 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_ME53 PF06061.6 AJW69812.1 - 2.6 6.9 10.7 0.29 10.0 1.0 2.7 1 1 2 3 3 3 0 Baculoviridae ME53 Yippee-Mis18 PF03226.9 AJW69812.1 - 4.5 7.3 9.8 2.7 8.1 0.4 3.1 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.7 AJW69812.1 - 4.9 6.5 12.1 29 4.1 0.4 3.6 2 2 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.14 AJW69812.1 - 5.2 6.7 12.0 9.3e+02 -0.5 8.3 2.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Nudix_N_2 PF14803.1 AJW69812.1 - 5.8 6.6 11.4 38 4.0 0.1 4.1 4 0 0 4 4 4 0 Nudix N-terminal Rpr2 PF04032.11 AJW69812.1 - 9.3 6.2 8.9 66 3.4 4.1 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PCNA_N PF00705.13 AJW69813.1 - 2e-19 69.3 0.1 3.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AJW69813.1 - 3.8e-16 59.1 0.9 4.2e-15 55.7 0.0 2.5 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 AJW69813.1 - 0.0046 16.1 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 Pox_A51 PF04948.8 AJW69813.1 - 0.035 12.7 0.7 0.044 12.4 0.2 1.4 2 0 0 2 2 2 0 Poxvirus A51 protein Receptor_2B4 PF11465.3 AJW69813.1 - 0.1 12.5 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 AA_kinase PF00696.23 AJW69814.1 - 3.1e-56 190.6 1.2 6.8e-56 189.5 0.8 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 AJW69814.1 - 2.1e-22 78.1 1.5 3.6e-10 39.1 0.0 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 AJW69814.1 - 3.3e-21 74.5 3.5 7.9e-12 44.5 0.1 2.6 2 0 0 2 2 2 2 ACT domain LytR_C PF13399.1 AJW69814.1 - 0.0073 16.6 0.2 0.48 10.8 0.0 3.0 2 1 1 3 3 3 1 LytR cell envelope-related transcriptional attenuator ACT_6 PF13740.1 AJW69814.1 - 0.0081 15.8 0.7 0.11 12.2 0.0 3.0 3 0 0 3 3 3 1 ACT domain Lant_dehyd_C PF04738.8 AJW69814.1 - 0.061 11.5 1.8 0.09 10.9 1.2 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus LsmAD PF06741.8 AJW69814.1 - 0.12 12.4 1.6 0.28 11.2 1.1 1.6 1 0 0 1 1 1 0 LsmAD domain TP_methylase PF00590.15 AJW69816.1 - 3.2e-35 121.7 0.0 3.8e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1522 PF07482.6 AJW69816.1 - 0.076 13.1 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) tRNA-synt_1b PF00579.20 AJW69817.1 - 9.8e-40 136.4 0.1 1.2e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) U3_snoRNA_assoc PF08297.6 AJW69818.1 - 0.091 13.0 0.2 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 U3 snoRNA associated zf-C2H2 PF00096.21 AJW69819.1 - 3.5e-09 36.4 8.4 0.00027 21.0 1.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AJW69819.1 - 2.2e-08 33.8 4.9 0.001 19.2 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger TF_Zn_Ribbon PF08271.7 AJW69819.1 - 0.00012 21.2 0.3 0.096 12.0 0.0 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 AJW69819.1 - 0.00055 19.3 0.2 0.0015 17.9 0.1 1.8 1 1 0 1 1 1 1 zinc-ribbon domain zf-C2H2_6 PF13912.1 AJW69819.1 - 0.00069 19.4 2.1 0.00069 19.4 1.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-FPG_IleRS PF06827.9 AJW69819.1 - 0.00074 19.0 0.9 1 9.0 0.0 2.3 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS Rubredoxin PF00301.15 AJW69819.1 - 0.006 16.4 0.3 2 8.3 0.0 2.2 2 0 0 2 2 2 1 Rubredoxin Ribosomal_S27e PF01667.12 AJW69819.1 - 0.0072 15.8 0.3 0.082 12.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S27 Prok-RING_1 PF14446.1 AJW69819.1 - 0.016 14.9 5.9 0.26 11.0 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 AJW69819.1 - 0.017 14.3 3.5 0.091 12.0 1.4 2.3 1 1 1 2 2 2 0 zinc-ribbon domain PHF5 PF03660.9 AJW69819.1 - 0.017 15.1 1.9 0.017 15.1 1.3 1.1 1 0 0 1 1 1 0 PHF5-like protein Rad50_zn_hook PF04423.9 AJW69819.1 - 0.019 14.4 7.6 0.031 13.7 1.9 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_5 PF13719.1 AJW69819.1 - 0.02 14.4 5.0 0.85 9.2 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 AJW69819.1 - 0.023 14.5 5.8 0.039 13.7 4.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.1 AJW69819.1 - 0.026 14.2 5.0 0.92 9.2 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 AJW69819.1 - 0.033 13.9 1.3 0.033 13.9 0.9 2.5 1 1 1 2 2 2 0 BED zinc finger RNA_POL_M_15KD PF02150.11 AJW69819.1 - 0.039 13.6 2.8 0.31 10.7 0.2 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2H2_2 PF12756.2 AJW69819.1 - 0.044 13.8 7.9 1.5 9.0 1.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Yippee-Mis18 PF03226.9 AJW69819.1 - 0.05 13.6 4.0 0.084 12.9 2.8 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PyrI_C PF02748.10 AJW69819.1 - 0.057 12.8 3.4 2.2 7.8 0.1 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ADK_lid PF05191.9 AJW69819.1 - 0.061 12.9 2.9 3.4 7.4 0.3 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.1 AJW69819.1 - 0.069 12.8 2.1 0.069 12.8 1.4 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FYVE PF01363.16 AJW69819.1 - 0.074 12.9 7.2 0.13 12.1 2.6 2.0 1 1 1 2 2 2 0 FYVE zinc finger C1_2 PF03107.11 AJW69819.1 - 0.16 12.1 3.2 1 9.5 0.2 2.2 2 0 0 2 2 2 0 C1 domain Bunya_G2 PF03563.8 AJW69819.1 - 0.16 10.8 2.0 0.96 8.2 1.4 1.8 1 1 0 1 1 1 0 Bunyavirus glycoprotein G2 Rpr2 PF04032.11 AJW69819.1 - 0.18 11.6 5.3 0.26 11.1 3.3 1.5 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Desulfoferrod_N PF06397.7 AJW69819.1 - 0.25 10.7 2.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-Di19 PF05605.7 AJW69819.1 - 0.33 11.0 3.2 0.75 9.9 2.2 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 AJW69819.1 - 0.33 11.3 11.9 0.69 10.3 2.5 3.0 3 0 0 3 3 3 0 Zinc-finger double domain GFA PF04828.9 AJW69819.1 - 0.35 10.8 4.8 0.94 9.4 1.9 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme LIM PF00412.17 AJW69819.1 - 0.41 10.7 8.5 0.5 10.4 5.9 1.1 1 0 0 1 1 1 0 LIM domain zf-Mss51 PF13824.1 AJW69819.1 - 0.45 10.4 4.4 0.27 11.1 1.5 1.8 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3795 PF12675.2 AJW69819.1 - 0.53 10.4 9.3 0.62 10.2 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) OrfB_Zn_ribbon PF07282.6 AJW69819.1 - 0.58 9.8 6.6 4.1 7.1 4.6 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain GCC2_GCC3 PF07699.8 AJW69819.1 - 0.67 9.5 8.1 4 7.0 0.2 2.2 1 1 1 2 2 2 0 GCC2 and GCC3 RNHCP PF12647.2 AJW69819.1 - 0.7 9.7 6.2 5.4 6.9 0.2 2.0 1 1 1 2 2 2 0 RNHCP domain Zn-ribbon_8 PF09723.5 AJW69819.1 - 0.75 9.7 7.2 10 6.1 3.0 2.3 1 1 1 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 AJW69819.1 - 0.85 9.1 6.5 3.1 7.3 0.1 2.5 3 0 0 3 3 2 0 A2L zinc ribbon domain XPA_N PF01286.13 AJW69819.1 - 0.87 9.3 5.3 4.4 7.0 0.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-CHY PF05495.7 AJW69819.1 - 0.89 9.7 10.4 3.1 8.0 7.2 1.7 1 1 0 1 1 1 0 CHY zinc finger HypA PF01155.14 AJW69819.1 - 1.4 8.6 6.0 4 7.1 1.1 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 AJW69819.1 - 1.4 8.6 7.4 0.4 10.4 1.1 2.3 2 1 0 2 2 1 0 Uncharacterised protein family UPF0547 YhfH PF14149.1 AJW69819.1 - 2.7 7.8 8.6 11 5.8 0.1 2.4 2 1 0 2 2 2 0 YhfH-like protein Cytochrome-c551 PF10643.4 AJW69819.1 - 4.1 6.6 8.3 7.1 5.8 1.0 2.0 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Ribosomal_L37e PF01907.14 AJW69819.1 - 4.7 7.0 10.3 5.6 6.8 3.0 2.4 1 1 1 2 2 2 0 Ribosomal protein L37e zf-C2H2_3 PF13878.1 AJW69819.1 - 9.9 5.8 11.2 18 5.0 2.4 2.6 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO PepSY_TM_2 PF13703.1 AJW69820.1 - 1.4 9.1 5.4 1.4 9.1 2.2 2.2 1 1 1 2 2 2 0 PepSY-associated TM helix DegT_DnrJ_EryC1 PF01041.12 AJW69821.1 - 2.6e-115 385.3 0.0 2.9e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AJW69821.1 - 1.1e-10 41.0 0.1 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AJW69821.1 - 1.1e-08 34.2 1.2 9.2e-08 31.2 0.2 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AJW69821.1 - 1.8e-07 29.7 0.3 2.4e-07 29.4 0.2 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 AJW69821.1 - 2.4e-07 30.1 0.0 5.6e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase ComK PF06338.6 AJW69821.1 - 0.0039 16.6 0.1 0.0075 15.7 0.1 1.5 1 0 0 1 1 1 1 ComK protein OKR_DC_1 PF01276.15 AJW69821.1 - 0.0067 15.0 0.1 0.011 14.2 0.1 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain PA28_alpha PF02251.13 AJW69821.1 - 0.018 15.2 0.4 0.37 10.9 0.2 2.4 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit MtrA PF04208.9 AJW69822.1 - 2.3e-26 92.3 0.1 3e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A dUTPase_2 PF08761.6 AJW69823.1 - 8.2e-20 71.5 6.9 7.6e-15 55.4 0.2 2.0 1 1 1 2 2 2 2 dUTPase DUF550 PF04447.7 AJW69823.1 - 0.015 14.8 1.8 0.024 14.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF550) PRA-PH PF01503.12 AJW69823.1 - 0.035 14.3 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase PfkB PF00294.19 AJW69824.1 - 1.4e-23 83.4 0.3 2.5e-23 82.6 0.2 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AJW69824.1 - 1.3e-05 24.5 0.2 2.9e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 AJW69824.1 - 0.0016 17.7 0.2 0.89 8.7 0.1 2.4 2 1 0 2 2 2 2 Carbohydrate kinase OstA_2 PF13100.1 AJW69824.1 - 0.037 13.3 0.1 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 OstA-like protein Tap-RNA_bind PF09162.5 AJW69826.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Tap, RNA-binding zf-CDGSH PF09360.5 AJW69827.1 - 0.92 9.3 3.8 1.4 8.8 2.7 1.6 1 1 0 1 1 1 0 Iron-binding zinc finger CDGSH type Pro_isomerase PF00160.16 AJW69829.1 - 1.2e-49 168.4 0.1 1.3e-49 168.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HTH_23 PF13384.1 AJW69830.1 - 0.0049 16.4 0.0 0.0086 15.6 0.0 1.6 1 1 0 1 1 1 1 Homeodomain-like domain GntR PF00392.16 AJW69830.1 - 0.073 12.5 0.1 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.5 AJW69830.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.14 AJW69830.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB ATG16 PF08614.6 AJW69832.1 - 0.00044 20.1 8.9 0.00053 19.8 6.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Bap31 PF05529.7 AJW69832.1 - 0.017 14.6 0.4 0.021 14.3 0.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Reo_sigmaC PF04582.7 AJW69832.1 - 0.029 13.5 3.7 0.036 13.2 2.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3450 PF11932.3 AJW69832.1 - 0.029 13.6 1.3 0.039 13.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF641 PF04859.7 AJW69832.1 - 0.077 12.7 1.5 0.13 12.0 1.1 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) RmuC PF02646.11 AJW69832.1 - 0.083 11.7 4.9 0.11 11.2 3.4 1.2 1 0 0 1 1 1 0 RmuC family Med9 PF07544.8 AJW69832.1 - 0.11 12.2 5.0 0.19 11.5 3.2 1.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TBPIP PF07106.8 AJW69832.1 - 0.22 11.0 7.0 0.23 11.0 4.4 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CheY-binding PF09078.6 AJW69832.1 - 0.49 10.4 2.8 1.5 8.8 0.7 2.6 1 1 2 3 3 3 0 CheY binding FlaC_arch PF05377.6 AJW69832.1 - 0.51 10.2 7.6 1.8 8.5 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Sec2p PF06428.6 AJW69832.1 - 0.83 9.5 6.8 2.4 8.0 4.1 2.1 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Pox_A_type_inc PF04508.7 AJW69832.1 - 1.1 9.2 3.4 34 4.5 0.0 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat IncA PF04156.9 AJW69832.1 - 8 6.0 14.0 0.11 12.0 5.0 1.4 2 0 0 2 2 2 0 IncA protein FMN_red PF03358.10 AJW69833.1 - 1.7e-23 82.8 0.0 2.2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AJW69833.1 - 3.2e-08 33.3 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF2283 PF10049.4 AJW69833.1 - 0.0011 18.7 0.2 0.22 11.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2283) Ribosomal_L11 PF00298.14 AJW69833.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Nitroreductase PF00881.19 AJW69834.1 - 3.6e-29 101.7 0.0 4.8e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF2393 PF09624.5 AJW69835.1 - 0.037 13.5 1.2 0.069 12.6 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) LEA_2 PF03168.8 AJW69835.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF3794 PF12673.2 AJW69835.1 - 0.068 13.3 0.1 1.5 8.9 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3794) CopD PF05425.8 AJW69836.1 - 7.3e-16 58.2 0.6 7.3e-16 58.2 0.4 1.6 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.4 AJW69836.1 - 9.5e-06 25.4 5.1 1.3e-05 25.0 3.5 1.1 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) UPF0093 PF03653.8 AJW69836.1 - 0.00091 19.2 7.1 0.0019 18.1 4.9 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0093) Aa_trans PF01490.13 AJW69836.1 - 0.0059 15.1 2.3 0.0059 15.1 1.6 2.0 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein 7TM_GPCR_Srv PF10323.4 AJW69836.1 - 0.036 13.2 2.4 0.04 13.0 1.1 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF989 PF06181.6 AJW69836.1 - 0.062 12.3 1.6 0.062 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF989) DUF4149 PF13664.1 AJW69836.1 - 0.078 13.0 7.2 0.09 12.8 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Ytp1 PF10355.4 AJW69836.1 - 0.11 11.6 2.5 0.13 11.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) DUF3278 PF11683.3 AJW69836.1 - 0.19 11.7 3.7 0.44 10.5 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) Brr6_like_C_C PF10104.4 AJW69836.1 - 1.8 8.1 8.4 0.068 12.6 0.9 2.2 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain RTC PF01137.16 AJW69837.1 - 3.7e-73 245.0 0.4 4.3e-73 244.8 0.3 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 AJW69837.1 - 0.0028 17.6 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain GCD14 PF08704.5 AJW69837.1 - 0.025 14.0 0.0 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Gryzun PF07919.7 AJW69837.1 - 0.045 12.0 0.0 0.063 11.5 0.0 1.2 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi CTP_transf_2 PF01467.21 AJW69838.1 - 4.6e-17 62.5 0.0 5.9e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Aminotran_5 PF00266.14 AJW69839.1 - 1.9e-32 112.4 0.0 2.3e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AJW69839.1 - 0.002 16.4 0.0 0.003 15.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FKBP_C PF00254.23 AJW69840.1 - 3.9e-12 46.0 0.3 1.7e-11 43.9 0.1 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PIF1 PF05970.9 AJW69840.1 - 0.075 11.9 0.4 0.11 11.4 0.3 1.2 1 0 0 1 1 1 0 PIF1-like helicase Fe-ADH_2 PF13685.1 AJW69841.1 - 9.6e-68 228.1 1.1 1.2e-67 227.8 0.8 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 AJW69841.1 - 1.7e-24 86.2 0.3 1.2e-23 83.3 0.2 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 AJW69841.1 - 2.5e-05 23.3 0.1 0.00023 20.1 0.1 2.2 1 1 0 1 1 1 1 3-dehydroquinate synthase Proteasome PF00227.21 AJW69842.1 - 5.8e-51 172.4 0.2 6.6e-51 172.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Beta-Casp PF10996.3 AJW69843.1 - 2.4e-31 108.3 0.0 4.3e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 AJW69843.1 - 2.4e-20 73.0 0.0 5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 AJW69843.1 - 2.2e-14 53.0 0.0 6.3e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 AJW69843.1 - 3.9e-12 46.1 0.0 2.8e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AJW69843.1 - 0.015 15.0 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FimP PF09766.4 AJW69843.1 - 0.11 11.6 0.4 0.16 10.9 0.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF552 PF04472.7 AJW69844.1 - 2.7e-16 59.2 1.1 3e-16 59.0 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF552) H_kinase_N PF12282.3 AJW69844.1 - 0.0062 16.1 0.1 0.0095 15.5 0.1 1.2 1 0 0 1 1 1 1 Signal transduction histidine kinase DUF4546 PF15079.1 AJW69844.1 - 0.034 13.2 0.5 0.038 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) ThiI PF02568.9 AJW69845.1 - 1.2e-13 50.9 0.0 2.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 AJW69845.1 - 3.3e-08 32.4 0.1 2.2e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase DUF814 PF05670.8 AJW69845.1 - 2.1e-06 27.5 0.1 4.6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Asn_synthase PF00733.16 AJW69845.1 - 0.00015 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJW69845.1 - 0.017 14.3 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 AJW69845.1 - 0.081 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Peptidase_M24 PF00557.19 AJW69846.1 - 1.4e-53 181.5 0.0 1.8e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AJW69846.1 - 1.4e-11 45.0 0.0 2.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Methyltransf_31 PF13847.1 AJW69848.1 - 4.3e-18 65.3 0.0 5.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AJW69848.1 - 7.5e-17 61.2 0.2 2.1e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AJW69848.1 - 6.2e-15 55.4 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW69848.1 - 5.3e-14 52.2 0.0 8.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW69848.1 - 3.4e-12 46.6 0.0 7.5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW69848.1 - 3.8e-12 46.7 0.0 1.6e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW69848.1 - 7.4e-12 45.6 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJW69848.1 - 5.2e-07 29.1 0.0 9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 AJW69848.1 - 9.2e-06 25.1 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 AJW69848.1 - 3.9e-05 22.8 0.0 8.3e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 AJW69848.1 - 0.00012 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 AJW69848.1 - 0.0002 21.3 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AJW69848.1 - 0.0016 17.5 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 AJW69848.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.8 AJW69848.1 - 0.0044 16.1 0.1 0.0077 15.3 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.13 AJW69848.1 - 0.0099 15.1 2.3 0.026 13.8 0.1 2.5 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain MetW PF07021.7 AJW69848.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.7 AJW69848.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_5 PF01795.14 AJW69848.1 - 0.13 11.4 0.4 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 MraW methylase family DUF2630 PF10944.3 AJW69849.1 - 0.0087 16.1 0.8 0.011 15.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) IMD PF08397.6 AJW69849.1 - 0.034 13.4 3.8 0.035 13.4 2.6 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain Carb_anhydrase PF00194.16 AJW69849.1 - 0.053 12.4 0.1 0.055 12.4 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase Tho2 PF11262.3 AJW69849.1 - 0.61 9.0 3.8 0.59 9.1 2.6 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ComC PF03047.9 AJW69849.1 - 0.89 9.0 6.3 1.3 8.4 0.2 2.5 1 1 1 2 2 2 0 COMC family DFP PF04127.10 AJW69850.1 - 4.7e-56 189.3 3.2 1.1e-53 181.6 1.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.14 AJW69850.1 - 5.2e-27 94.0 3.4 5.2e-27 94.0 0.1 2.3 2 1 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.1 AJW69850.1 - 0.0013 18.9 4.0 0.17 12.1 0.1 3.5 4 0 0 4 4 4 2 Putative NAD(P)-binding NAD_binding_10 PF13460.1 AJW69850.1 - 0.0015 18.5 0.0 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding YjeF_N PF03853.10 AJW69850.1 - 0.021 14.4 0.1 3 7.4 0.0 2.7 3 0 0 3 3 3 0 YjeF-related protein N-terminus BRCT PF00533.21 AJW69850.1 - 0.05 13.7 0.4 0.49 10.5 0.0 2.6 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Pantoate_transf PF02548.10 AJW69851.1 - 5e-108 360.1 2.6 5.6e-108 359.9 1.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 AJW69851.1 - 1.1e-05 24.8 0.3 3.7e-05 23.0 0.1 1.9 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase ORF6N PF10543.4 AJW69851.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 ORF6N domain Peptidase_U32 PF01136.14 AJW69851.1 - 0.049 12.5 0.1 0.95 8.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase family U32 DUF137 PF02006.11 AJW69852.1 - 2e-73 245.5 4.1 2.5e-73 245.2 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF137 Orexin_rec2 PF03827.8 AJW69852.1 - 0.12 12.4 0.7 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Orexin receptor type 2 GHMP_kinases_N PF00288.21 AJW69853.1 - 4e-11 42.8 0.1 7e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJW69853.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal PhoU PF01895.14 AJW69854.1 - 8.7e-10 38.9 5.1 9.6e-07 29.1 1.5 2.5 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 AJW69854.1 - 6.7e-08 32.0 0.1 1.8e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Antidote-toxin recognition MazE NUDIX PF00293.23 AJW69855.1 - 2.9e-18 65.7 0.0 3.7e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AF0941-like PF14591.1 AJW69855.1 - 0.085 12.9 0.4 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 AF0941-like HTH_24 PF13412.1 AJW69856.1 - 6.9e-20 70.1 9.6 2.1e-10 39.8 0.7 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AJW69856.1 - 1.7e-18 65.8 1.7 5.7e-10 38.5 0.1 2.3 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain TrmB PF01978.14 AJW69856.1 - 1.7e-07 30.8 0.1 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AJW69856.1 - 5.1e-06 26.0 0.4 0.0026 17.3 0.1 2.6 2 0 0 2 2 2 2 HTH domain MarR_2 PF12802.2 AJW69856.1 - 1.2e-05 24.8 0.0 0.0091 15.6 0.0 2.3 2 0 0 2 2 2 2 MarR family MarR PF01047.17 AJW69856.1 - 1.9e-05 24.2 2.1 0.0009 18.9 0.1 2.9 3 0 0 3 3 3 1 MarR family HTH_Mga PF08280.6 AJW69856.1 - 2.6e-05 23.8 4.2 9.1e-05 22.1 0.7 2.9 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_23 PF13384.1 AJW69856.1 - 0.0003 20.3 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain Trp_repressor PF01371.14 AJW69856.1 - 0.0017 18.2 1.0 0.0057 16.5 0.1 2.3 2 0 0 2 2 2 1 Trp repressor protein Mga PF05043.8 AJW69856.1 - 0.0025 18.0 0.8 0.11 12.8 0.1 3.1 3 0 0 3 3 3 1 Mga helix-turn-helix domain HTH_34 PF13601.1 AJW69856.1 - 0.0075 16.2 0.0 2.3 8.3 0.0 2.7 3 0 0 3 3 2 1 Winged helix DNA-binding domain GerE PF00196.14 AJW69856.1 - 0.015 14.6 4.7 0.14 11.5 0.2 3.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family HTH_DeoR PF08220.7 AJW69856.1 - 0.024 14.1 0.2 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_28 PF13518.1 AJW69856.1 - 0.029 14.3 0.0 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_45 PF14947.1 AJW69856.1 - 0.031 14.0 1.0 0.4 10.5 0.1 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix HTH_27 PF13463.1 AJW69856.1 - 0.031 14.5 0.1 0.95 9.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_36 PF13730.1 AJW69856.1 - 0.054 13.6 0.6 0.55 10.4 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.1 AJW69856.1 - 0.069 13.3 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix TFIIE_alpha PF02002.12 AJW69856.1 - 0.6 9.6 4.5 12 5.4 0.1 2.9 3 0 0 3 3 3 0 TFIIE alpha subunit MacB_PCD PF12704.2 AJW69857.1 - 1.7e-24 86.6 2.0 3.5e-24 85.6 1.4 1.5 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.16 AJW69857.1 - 3.1e-19 68.9 7.1 3.1e-19 68.9 4.9 1.9 2 0 0 2 2 2 1 FtsX-like permease family ABC_tran PF00005.22 AJW69858.1 - 1.3e-19 70.8 0.0 1.9e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJW69858.1 - 6.1e-05 23.1 0.1 8.4e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJW69858.1 - 6.6e-05 22.2 0.3 8.9e-05 21.8 0.2 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 AJW69858.1 - 0.0079 16.0 0.0 0.24 11.3 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 AJW69858.1 - 0.0086 14.5 0.1 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AviRa PF11599.3 AJW69858.1 - 0.0099 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa AAA_15 PF13175.1 AJW69858.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NPCBM_assoc PF10633.4 AJW69859.1 - 0.00073 19.5 0.6 1.2 9.1 0.0 4.1 3 2 1 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase Rib PF08428.5 AJW69859.1 - 0.03 14.0 0.1 0.089 12.5 0.1 1.8 1 0 0 1 1 1 0 Rib/alpha-like repeat Cast PF10174.4 AJW69860.1 - 4e-06 25.2 8.3 4.9e-06 24.9 5.8 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone MacB_PCD PF12704.2 AJW69860.1 - 0.00054 19.6 0.1 0.00058 19.5 0.0 1.1 1 0 0 1 1 1 1 MacB-like periplasmic core domain HemX PF04375.9 AJW69860.1 - 0.0053 15.4 0.4 0.0065 15.1 0.3 1.0 1 0 0 1 1 1 1 HemX DUF342 PF03961.8 AJW69860.1 - 0.0063 14.9 5.2 0.007 14.8 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF1041 PF06292.12 AJW69860.1 - 0.013 15.6 3.4 0.017 15.2 2.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) YlqD PF11068.3 AJW69860.1 - 0.014 15.4 4.6 0.017 15.1 3.2 1.1 1 0 0 1 1 1 0 YlqD protein Spc7 PF08317.6 AJW69860.1 - 0.024 13.2 9.7 0.029 13.0 6.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1043 PF06295.7 AJW69860.1 - 0.03 13.9 5.8 0.3 10.7 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Allexi_40kDa PF05549.6 AJW69860.1 - 0.045 13.0 2.4 0.048 12.9 1.7 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1186 PF06685.6 AJW69860.1 - 0.055 12.6 5.3 0.99 8.5 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1186) UPF0118 PF01594.11 AJW69860.1 - 0.056 12.4 0.3 0.061 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 FixH PF05751.6 AJW69860.1 - 0.067 13.0 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 FixH Ax_dynein_light PF10211.4 AJW69860.1 - 0.073 12.9 9.9 0.09 12.6 6.8 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain THUMP PF02926.12 AJW69860.1 - 0.083 12.7 2.0 0.11 12.3 1.4 1.1 1 0 0 1 1 1 0 THUMP domain BMFP PF04380.8 AJW69860.1 - 0.085 13.0 4.5 0.14 12.3 3.1 1.4 1 1 0 1 1 1 0 Membrane fusogenic activity TMCO5 PF14992.1 AJW69860.1 - 0.096 11.8 7.1 0.12 11.5 4.9 1.1 1 0 0 1 1 1 0 TMCO5 family HAND PF09110.6 AJW69860.1 - 0.11 12.9 5.6 0.14 12.5 3.9 1.1 1 0 0 1 1 1 0 HAND DUF4446 PF14584.1 AJW69860.1 - 0.11 12.3 3.8 0.19 11.5 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) CorA PF01544.13 AJW69860.1 - 0.14 11.1 5.3 0.21 10.5 3.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Stn1 PF10451.4 AJW69860.1 - 0.15 10.8 3.7 0.43 9.3 2.6 1.8 1 1 0 1 1 1 0 Telomere regulation protein Stn1 PKK PF12474.3 AJW69860.1 - 0.17 11.6 7.2 0.22 11.2 5.0 1.3 1 1 0 1 1 1 0 Polo kinase kinase P5-ATPase PF12409.3 AJW69860.1 - 0.18 11.6 1.5 0.22 11.3 1.0 1.2 1 0 0 1 1 1 0 P5-type ATPase cation transporter Psu PF07455.6 AJW69860.1 - 0.23 10.9 1.9 0.26 10.7 1.3 1.1 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) TMPIT PF07851.8 AJW69860.1 - 0.35 9.9 7.3 0.4 9.6 5.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3373 PF11853.3 AJW69860.1 - 0.37 9.2 1.8 0.37 9.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) COG2 PF06148.6 AJW69860.1 - 0.42 10.4 5.6 2.1 8.2 3.8 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.6 AJW69860.1 - 0.8 10.1 7.6 1.4 9.4 4.9 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Uds1 PF15456.1 AJW69860.1 - 1.4 8.9 5.7 2.9 7.9 4.0 1.4 1 1 0 1 1 1 0 Up-regulated During Septation pRN1_helical PF13010.1 AJW69860.1 - 1.4 8.5 6.1 1.8 8.1 4.2 1.1 1 0 0 1 1 1 0 Primase helical domain DUF3450 PF11932.3 AJW69860.1 - 1.4 8.0 9.3 4.7 6.3 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.6 AJW69860.1 - 1.5 8.7 11.6 16 5.3 8.0 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KNOX2 PF03791.8 AJW69860.1 - 1.5 8.1 4.4 0.64 9.3 0.8 2.1 2 1 0 2 2 2 0 KNOX2 domain DUF3847 PF12958.2 AJW69860.1 - 1.8 8.4 7.8 1.1 9.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Halogen_Hydrol PF10112.4 AJW69860.1 - 1.8 7.9 8.5 1.6 8.1 5.3 1.4 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Atg14 PF10186.4 AJW69860.1 - 2.2 7.1 6.6 2.9 6.7 4.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Streptin-Immun PF11083.3 AJW69860.1 - 2.3 8.2 10.0 26 4.8 6.5 2.0 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein FUN14 PF04930.10 AJW69860.1 - 4.1 7.7 6.6 22 5.3 4.6 2.0 1 1 0 1 1 1 0 FUN14 family Ribosomal_S13 PF00416.17 AJW69860.1 - 4.6 7.7 6.2 5.6 7.4 3.4 1.6 1 1 1 2 2 2 0 Ribosomal protein S13/S18 4HB_MCP_1 PF12729.2 AJW69860.1 - 5.7 6.2 13.3 14 4.9 9.2 1.7 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF4404 PF14357.1 AJW69860.1 - 6.7 7.2 7.5 2.7 8.4 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) zf-C4H2 PF10146.4 AJW69860.1 - 7.8 6.4 8.5 9.9 6.1 5.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein ABC2_membrane_5 PF13346.1 AJW69861.1 - 0.0022 17.3 1.2 0.0026 17.1 0.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF165 PF02592.10 AJW69861.1 - 0.0046 17.1 0.6 0.005 17.0 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YhhQ family COG1738 SdpI PF13630.1 AJW69861.1 - 0.0057 16.3 1.0 0.0071 16.0 0.7 1.1 1 0 0 1 1 1 1 SdpI/YhfL protein family DUF969 PF06149.7 AJW69861.1 - 0.039 13.1 0.2 0.043 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF969) DUF1119 PF06550.6 AJW69861.1 - 0.045 12.8 0.4 0.05 12.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) MatC_N PF07158.6 AJW69861.1 - 0.047 13.5 0.4 0.047 13.5 0.3 1.0 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus Class_IIIsignal PF04021.7 AJW69861.1 - 0.066 12.9 1.0 0.066 12.9 0.7 2.0 2 0 0 2 2 2 0 Class III signal peptide MpPF26 PF07666.6 AJW69861.1 - 1.9 8.4 5.3 2.8 7.8 0.3 2.0 1 1 1 2 2 2 0 M penetrans paralogue family 26 RRF_GI PF12614.3 AJW69862.1 - 0.024 14.4 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF1129 PF06570.6 AJW69862.1 - 0.099 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ABC1 PF03109.11 AJW69863.1 - 2.9e-24 85.3 0.0 1e-23 83.5 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 AJW69863.1 - 0.06 13.0 0.0 0.22 11.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family NAAA-beta PF15508.1 AJW69863.1 - 0.19 12.1 1.2 24 5.3 0.0 3.5 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HSP20 PF00011.16 AJW69864.1 - 2.8e-12 46.3 0.4 3.8e-12 45.9 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Staphostatin_A PF09022.5 AJW69864.1 - 0.1 12.4 1.4 0.16 11.8 0.9 1.4 1 0 0 1 1 1 0 Staphostatin A DUF217 PF02697.9 AJW69866.1 - 1.4 9.1 4.3 2.2 8.6 3.0 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, COG1753 SSP160 PF06933.6 AJW69867.1 - 0.35 8.7 2.0 0.35 8.7 1.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1272 PF06906.6 AJW69867.1 - 0.44 10.4 3.4 1.2 9.0 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-TFIIB PF13453.1 AJW69867.1 - 0.46 9.7 2.6 5.5 6.2 0.9 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-RING_4 PF14570.1 AJW69867.1 - 0.51 9.9 4.8 0.73 9.4 3.3 1.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TrmB PF01978.14 AJW69868.1 - 8e-05 22.2 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.6 AJW69868.1 - 0.057 13.0 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_20 PF12840.2 AJW69868.1 - 0.059 13.1 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.15 AJW69868.1 - 0.11 12.1 0.3 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AJW69868.1 - 0.12 11.7 0.3 0.33 10.3 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Intron_maturas2 PF01348.16 AJW69869.1 - 0.0078 16.1 0.0 0.0098 15.8 0.0 1.1 1 0 0 1 1 1 1 Type II intron maturase A_thal_3526 PF09713.5 AJW69869.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) NMT_C PF02799.10 AJW69869.1 - 0.084 12.2 0.1 0.11 11.8 0.1 1.2 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Thymidylate_kin PF02223.12 AJW69870.1 - 1.8e-37 128.4 0.7 2.1e-37 128.3 0.5 1.0 1 0 0 1 1 1 1 Thymidylate kinase PRK PF00485.13 AJW69870.1 - 0.018 14.6 0.0 0.061 12.8 0.0 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family dNK PF01712.14 AJW69870.1 - 0.042 13.7 1.1 0.074 12.9 0.7 1.4 1 1 0 1 1 1 0 Deoxynucleoside kinase HPIH PF13323.1 AJW69870.1 - 0.11 12.2 0.3 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain with HPIH motif DUF2183 PF09949.4 AJW69870.1 - 0.54 10.2 3.5 0.59 10.0 0.8 2.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2183) HD PF01966.17 AJW69871.1 - 2.9e-16 59.5 0.3 6.1e-16 58.5 0.2 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 AJW69871.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 HDOD domain AA_kinase PF00696.23 AJW69872.1 - 2.3e-32 112.4 1.4 2.9e-32 112.1 0.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family Vac7 PF12751.2 AJW69874.1 - 0.047 12.5 0.1 0.063 12.1 0.1 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Cas_Cas4 PF01930.12 AJW69876.1 - 6.9e-05 22.8 0.9 0.00014 21.7 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 AJW69876.1 - 0.021 14.2 1.3 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Peptidase_A24 PF01478.13 AJW69877.1 - 0.048 13.8 1.6 0.058 13.5 1.1 1.1 1 0 0 1 1 1 0 Type IV leader peptidase family vATP-synt_AC39 PF01992.11 AJW69878.1 - 1.6e-38 132.7 10.7 1.9e-38 132.4 7.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DNA_ligase_OB PF03120.11 AJW69878.1 - 0.15 11.6 0.2 36 4.1 0.0 3.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase OB-fold domain Ammonium_transp PF00909.16 AJW69880.1 - 3.5e-109 364.9 35.5 8e-109 363.7 24.6 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family TcdA_TcdB_pore PF12920.2 AJW69880.1 - 8.1 4.2 4.6 12 3.6 3.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Rhodanese PF00581.15 AJW69881.1 - 2.7e-41 140.4 0.1 8.9e-21 74.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain GOLD_2 PF13897.1 AJW69882.1 - 0.16 12.2 4.5 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking V_ATPase_I PF01496.14 AJW69883.1 - 4.8e-58 196.7 16.0 1.3e-57 195.2 11.1 1.5 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF948 PF06103.6 AJW69883.1 - 0.014 15.2 3.0 1.9 8.4 0.1 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) THOC7 PF05615.8 AJW69883.1 - 0.082 13.1 4.6 1.1 9.5 0.4 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 MerR-DNA-bind PF09278.6 AJW69883.1 - 0.1 12.9 0.1 1.1 9.7 0.2 2.2 2 0 0 2 2 2 0 MerR, DNA binding V-SNARE PF05008.10 AJW69883.1 - 2.6 8.2 8.6 14 5.9 1.0 3.5 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Kri1 PF05178.7 AJW69883.1 - 4.3 7.6 8.5 21 5.4 0.4 2.5 2 1 0 2 2 2 0 KRI1-like family vATP-synt_E PF01991.13 AJW69884.1 - 1.1e-20 73.8 7.9 1.3e-19 70.2 4.8 2.6 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit DUF3510 PF12022.3 AJW69884.1 - 0.046 13.8 1.1 0.086 12.9 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) YtzH PF14165.1 AJW69884.1 - 0.1 12.8 1.7 2.3 8.5 0.0 2.9 2 1 0 3 3 3 0 YtzH-like protein ATP-synt_B PF00430.13 AJW69884.1 - 0.11 12.3 5.1 0.19 11.5 3.5 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Prominin PF05478.6 AJW69884.1 - 0.17 9.3 0.9 0.21 9.0 0.6 1.1 1 0 0 1 1 1 0 Prominin ATP-synt_ab PF00006.20 AJW69885.1 - 1.9e-96 321.6 0.0 2.7e-96 321.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AJW69885.1 - 1.5e-14 54.4 1.2 3.1e-14 53.4 0.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AJW69885.1 - 8.8e-13 48.2 0.3 2e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.1 AJW69885.1 - 0.0022 17.6 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AJW69885.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.7 AJW69885.1 - 0.096 11.0 0.4 0.16 10.3 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ATP-synt_ab PF00006.20 AJW69886.1 - 3.3e-64 216.3 0.0 4.5e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AJW69886.1 - 9.5e-14 51.8 0.2 1.7e-13 50.9 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AJW69886.1 - 2.8e-11 43.4 1.8 6.6e-11 42.2 1.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AJW69886.1 - 2.2e-05 24.2 1.3 0.00011 22.0 0.6 2.2 2 0 0 2 2 2 1 HAS barrel domain ATP-synt_D PF01813.12 AJW69887.1 - 8.6e-52 175.5 6.8 9.7e-52 175.3 4.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit D PMC2NT PF08066.7 AJW69887.1 - 0.0043 17.3 0.3 1 9.6 0.0 2.6 2 1 0 2 2 2 1 PMC2NT (NUC016) domain PerC PF06069.6 AJW69887.1 - 0.061 13.3 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 PerC transcriptional activator Skp1_POZ PF03931.10 AJW69887.1 - 0.13 12.4 0.4 0.49 10.5 0.1 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain DUF1395 PF07160.7 AJW69887.1 - 0.17 11.3 6.2 1.2 8.5 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) DUF1019 PF06254.6 AJW69887.1 - 2.2 8.5 6.5 1.5 9.0 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1019) RICH PF05062.7 AJW69888.1 - 0.01 15.9 2.5 0.056 13.5 0.5 2.0 1 1 1 2 2 2 0 RICH domain MbeB_N PF04837.7 AJW69888.1 - 0.074 13.1 0.4 0.091 12.8 0.3 1.3 1 1 0 1 1 1 0 MbeB-like, N-term conserved region GrpE PF01025.14 AJW69888.1 - 0.09 12.3 1.2 0.099 12.1 0.8 1.0 1 0 0 1 1 1 0 GrpE ATP-synt_C PF00137.16 AJW69889.1 - 4.1e-20 71.4 17.0 4.1e-20 71.4 11.8 2.0 2 0 0 2 2 2 1 ATP synthase subunit C PyrI PF01948.13 AJW69890.1 - 2.5e-35 120.3 1.6 4.3e-35 119.6 1.1 1.4 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.10 AJW69890.1 - 7.6e-15 54.0 1.9 1.3e-14 53.3 1.3 1.4 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1936 PF09151.5 AJW69890.1 - 0.024 14.1 0.2 0.056 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) OTCace_N PF02729.16 AJW69891.1 - 7.4e-41 139.1 0.0 1.1e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AJW69891.1 - 2.2e-37 128.3 0.0 3.2e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LON PF02190.11 AJW69892.1 - 2.6e-17 63.2 0.2 3.8e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Cdc6_C PF09079.6 AJW69894.1 - 2.9e-07 30.1 0.0 9.1e-07 28.5 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal AAA PF00004.24 AJW69894.1 - 4.1e-07 30.2 0.0 1.4e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AJW69894.1 - 6.2e-07 29.5 0.0 4.7e-05 23.4 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 AJW69894.1 - 1.1e-06 28.4 3.0 7.2e-06 25.8 1.4 2.5 1 1 1 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 AJW69894.1 - 1.2e-06 28.7 0.0 4e-06 26.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AJW69894.1 - 1.5e-05 25.8 0.1 5.9e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 AJW69894.1 - 0.00023 20.1 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF815 PF05673.8 AJW69894.1 - 0.0026 16.7 0.0 0.023 13.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 AJW69894.1 - 0.0028 17.9 0.0 0.021 15.1 0.0 2.4 3 0 0 3 3 2 1 ABC transporter AAA_23 PF13476.1 AJW69894.1 - 0.0036 17.6 1.1 0.038 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AJW69894.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 AJW69894.1 - 0.0097 15.8 4.2 0.095 12.6 2.9 2.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AJW69894.1 - 0.013 15.6 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.1 AJW69894.1 - 0.024 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 AJW69894.1 - 0.054 13.3 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AJW69894.1 - 0.07 13.4 0.2 0.28 11.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AJW69894.1 - 0.093 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 AJW69894.1 - 0.099 11.8 0.1 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Cation_efflux PF01545.16 AJW69895.1 - 3.8e-18 65.5 12.9 6.9e-17 61.4 8.9 1.9 1 1 0 1 1 1 1 Cation efflux family IncA PF04156.9 AJW69895.1 - 1.8 8.1 7.3 10 5.6 1.3 2.4 2 0 0 2 2 2 0 IncA protein MethyTransf_Reg PF10119.4 AJW69896.1 - 0.036 14.5 6.8 30 5.1 0.0 5.0 4 1 1 5 5 5 0 Predicted methyltransferase regulatory domain PSII_BNR PF14870.1 AJW69897.1 - 1.8e-07 30.4 1.1 2.7e-05 23.3 0.1 2.6 1 1 1 2 2 2 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 AJW69897.1 - 7.2e-07 28.1 14.3 0.14 12.0 0.1 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat DUF4185 PF13810.1 AJW69897.1 - 0.0067 15.3 0.3 1.6 7.5 0.0 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4185) BNR_2 PF13088.1 AJW69897.1 - 0.011 15.0 0.1 0.051 12.8 0.1 2.1 1 1 0 1 1 1 0 BNR repeat-like domain SBBP PF06739.6 AJW69897.1 - 0.037 13.8 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Beta-propeller repeat Cation_efflux PF01545.16 AJW69900.1 - 1.7e-66 224.2 19.5 2e-66 223.9 13.6 1.0 1 0 0 1 1 1 1 Cation efflux family MerC PF03203.9 AJW69900.1 - 0.007 16.7 11.0 0.24 11.7 1.8 2.8 1 1 1 2 2 2 2 MerC mercury resistance protein WSN PF02206.13 AJW69900.1 - 0.057 13.1 0.2 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF4181 PF13789.1 AJW69900.1 - 1.9 8.4 14.7 0.079 12.8 0.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4181) SGL PF08450.7 AJW69901.1 - 8.7e-11 41.6 0.4 0.049 12.9 0.0 4.9 2 1 2 4 4 4 4 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 AJW69901.1 - 0.00014 21.6 0.6 0.074 13.0 0.0 3.9 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.6 AJW69901.1 - 0.00037 20.1 8.5 7.3 6.9 0.0 5.9 5 0 0 5 5 5 2 Two component regulator propeller HTH_24 PF13412.1 AJW69902.1 - 5.1e-12 44.9 0.3 8.7e-07 28.2 0.1 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AJW69902.1 - 1.3e-06 28.1 0.0 0.0008 19.1 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain TrmB PF01978.14 AJW69902.1 - 1.7e-06 27.6 0.2 0.0012 18.4 0.1 2.6 1 1 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AJW69902.1 - 0.0003 20.2 0.0 0.0069 15.9 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain FUR PF01475.14 AJW69902.1 - 0.0005 19.9 0.0 0.0012 18.7 0.0 1.8 1 1 1 2 2 2 1 Ferric uptake regulator family HTH_5 PF01022.15 AJW69902.1 - 0.0022 17.5 0.0 0.086 12.5 0.0 2.5 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.2 AJW69902.1 - 0.0031 17.1 0.0 0.77 9.4 0.0 3.0 2 1 0 3 3 3 1 MarR family HTH_34 PF13601.1 AJW69902.1 - 0.0055 16.7 0.0 4.2 7.4 0.0 2.4 2 1 0 2 2 2 2 Winged helix DNA-binding domain HTH_AsnC-type PF13404.1 AJW69902.1 - 0.009 15.5 0.1 0.066 12.7 0.1 2.3 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AJW69902.1 - 0.01 15.4 1.4 0.11 12.2 0.0 2.6 3 1 0 3 3 3 0 HTH domain HTH_23 PF13384.1 AJW69902.1 - 0.017 14.7 0.0 0.54 9.9 0.0 2.7 2 1 1 3 3 3 0 Homeodomain-like domain HTH_27 PF13463.1 AJW69902.1 - 0.028 14.7 0.0 3 8.2 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.13 AJW69902.1 - 0.059 13.4 0.5 0.21 11.6 0.1 2.2 2 1 0 2 2 2 0 Transposase DUF1143 PF06608.6 AJW69902.1 - 0.12 12.3 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) PadR PF03551.9 AJW69902.1 - 0.12 12.1 0.9 1.7 8.4 0.2 2.6 3 1 0 3 3 3 0 Transcriptional regulator PadR-like family DUF2250 PF10007.4 AJW69902.1 - 0.13 12.2 0.5 0.37 10.7 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) YiaAB PF05360.9 AJW69903.1 - 0.014 14.9 0.2 0.014 14.9 0.1 3.1 3 1 0 3 3 3 0 yiaA/B two helix domain DUF1129 PF06570.6 AJW69903.1 - 0.2 10.9 4.7 0.068 12.4 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3816 PF12822.2 AJW69903.1 - 0.35 10.7 11.3 0.59 9.9 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Copper-bind PF00127.15 AJW69904.1 - 3.5e-06 27.1 0.0 7.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW69904.1 - 0.019 14.8 0.0 0.12 12.2 0.0 2.4 1 1 0 1 1 1 0 Cupredoxin-like domain hSac2 PF12456.3 AJW69905.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol phosphatase LCAT PF02450.10 AJW69906.1 - 0.018 14.0 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GHL12 PF14882.1 AJW69907.1 - 5.1e-15 55.2 10.4 0.00034 20.6 0.3 3.5 3 0 0 3 3 3 3 Hypothetical glycosyl hydrolase 12 Inhibitor_I29 PF08246.7 AJW69907.1 - 0.0066 16.6 3.7 1.5 9.1 0.0 3.2 3 0 0 3 3 3 2 Cathepsin propeptide inhibitor domain (I29) DUF2717 PF10911.3 AJW69907.1 - 0.015 14.7 0.1 11 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2717) Hormone_2 PF00123.15 AJW69907.1 - 0.1 12.4 4.3 6.1 6.7 0.1 2.9 3 0 0 3 3 3 0 Peptide hormone Mso1_Sec1_bdg PF14475.1 AJW69907.1 - 6.7 6.2 6.9 8.1 5.9 0.2 2.9 3 0 0 3 3 3 0 Sec1-binding region of Mso1 Cu-oxidase_3 PF07732.10 AJW69908.1 - 1.3e-07 31.3 0.6 9.9e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AJW69908.1 - 0.0011 18.4 0.5 0.53 9.7 0.1 2.6 2 1 0 2 2 2 2 Multicopper oxidase DUF95 PF01944.12 AJW69909.1 - 5.4e-07 29.4 14.8 5.4e-07 29.4 10.3 1.4 1 1 1 2 2 2 2 Integral membrane protein DUF95 Thioredoxin_4 PF13462.1 AJW69910.1 - 6.5e-42 143.2 0.0 1e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJW69910.1 - 5.6e-22 78.2 0.1 1.1e-12 47.8 0.0 2.3 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJW69910.1 - 2e-10 40.8 0.0 6.3e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 AJW69910.1 - 0.0035 16.9 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HTH_AsnC-type PF13404.1 AJW69911.1 - 2.1e-14 52.7 0.2 2.9e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AJW69911.1 - 8.3e-12 44.2 0.2 1.2e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Arc_trans_TRASH PF08394.5 AJW69911.1 - 2e-07 31.0 5.8 3.6e-07 30.2 4.0 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain Sigma70_r4_2 PF08281.7 AJW69911.1 - 0.00037 19.8 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 TrmB PF01978.14 AJW69911.1 - 0.00046 19.8 0.0 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.1 AJW69911.1 - 0.00046 20.1 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 AJW69911.1 - 0.00052 19.5 0.0 0.00089 18.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 AJW69911.1 - 0.0013 17.8 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF2250 PF10007.4 AJW69911.1 - 0.002 17.9 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_5 PF01022.15 AJW69911.1 - 0.0039 16.8 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.17 AJW69911.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 1 1 MarR family FeoC PF09012.5 AJW69911.1 - 0.0064 16.1 0.1 0.0064 16.1 0.1 2.4 2 2 1 3 3 3 1 FeoC like transcriptional regulator GerE PF00196.14 AJW69911.1 - 0.011 14.9 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family MarR_2 PF12802.2 AJW69911.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.14 AJW69911.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain LexA_DNA_bind PF01726.11 AJW69911.1 - 0.037 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain DUF2089 PF09862.4 AJW69911.1 - 0.055 13.2 0.2 0.14 11.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2089) DUF4423 PF14394.1 AJW69911.1 - 0.057 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_38 PF13936.1 AJW69911.1 - 0.067 12.7 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.7 AJW69911.1 - 0.075 12.6 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_psq PF05225.11 AJW69911.1 - 0.11 12.1 0.2 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Rrf2 PF02082.15 AJW69911.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_7 PF02796.10 AJW69911.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_20 PF12840.2 AJW69911.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Trypsin_2 PF13365.1 AJW69912.1 - 9.8e-22 77.1 0.1 1.8e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 AJW69912.1 - 5.9e-14 51.7 0.3 1.7e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.21 AJW69912.1 - 6.4e-13 48.7 0.2 1.5e-12 47.5 0.1 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.8 AJW69912.1 - 0.0086 15.0 1.3 0.96 8.3 0.1 2.2 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.10 AJW69912.1 - 0.015 14.8 0.0 0.045 13.2 0.0 1.8 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.4 AJW69912.1 - 0.015 13.7 0.5 0.015 13.7 0.3 1.7 2 0 0 2 2 2 0 Peptidase S46 PDZ PF00595.19 AJW69912.1 - 0.022 14.9 1.2 23 5.2 0.1 3.5 3 0 0 3 3 3 0 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 AJW69912.1 - 0.052 12.9 0.6 0.14 11.5 0.4 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 AJW69912.1 - 0.18 11.0 4.3 14 4.8 0.0 3.0 2 1 0 2 2 2 0 Putative peptidase (DUF31) 3D PF06725.6 AJW69913.1 - 1.5e-07 31.2 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 3D domain Thioredoxin_3 PF13192.1 AJW69914.1 - 9.3e-14 51.0 0.2 1.1e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.19 AJW69914.1 - 4.3e-10 39.4 0.1 6.1e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 AJW69914.1 - 7.4e-06 26.1 0.1 8.1e-06 26.0 0.1 1.2 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) ArsC PF03960.10 AJW69914.1 - 0.00029 20.8 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 ArsC family KaiB PF07689.7 AJW69914.1 - 0.0022 17.4 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin PF00085.15 AJW69914.1 - 0.004 16.7 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin GST_N_3 PF13417.1 AJW69914.1 - 0.018 15.2 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 AJW69914.1 - 0.11 12.6 0.4 0.82 9.8 0.1 1.9 1 1 1 2 2 2 0 Thioredoxin-like domain YHS PF04945.8 AJW69915.1 - 5.2e-15 55.0 2.0 5.6e-15 54.9 1.4 1.1 1 0 0 1 1 1 1 YHS domain Arc_trans_TRASH PF08394.5 AJW69915.1 - 0.00014 21.9 1.1 0.00018 21.6 0.7 1.1 1 0 0 1 1 1 1 Archaeal TRASH domain zf-FCS PF06467.9 AJW69915.1 - 0.00077 19.0 2.9 0.00092 18.8 1.7 1.4 1 1 1 2 2 2 1 MYM-type Zinc finger with FCS sequence motif DUF581 PF04570.9 AJW69915.1 - 0.0026 17.0 1.0 0.0029 16.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF581) Shisa PF13908.1 AJW69915.1 - 0.28 11.3 2.2 0.32 11.1 1.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DsbD PF02683.10 AJW69916.1 - 9.7e-19 67.8 17.5 9.7e-19 67.8 12.1 2.1 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 AJW69916.1 - 1.6e-08 34.5 22.8 1.6e-08 34.5 15.8 2.3 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF2182 PF09948.4 AJW69916.1 - 0.0061 16.4 7.0 0.024 14.5 4.8 1.9 1 1 0 1 1 1 1 Predicted metal-binding integral membrane protein (DUF2182) DUF3953 PF13129.1 AJW69916.1 - 0.071 12.7 0.5 0.071 12.7 0.3 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3953) DUF872 PF05915.7 AJW69916.1 - 4.5 7.1 16.9 0.5 10.2 1.5 3.3 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Thioredoxin_4 PF13462.1 AJW69917.1 - 2.3e-35 122.0 0.0 2.8e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJW69917.1 - 4.9e-15 55.5 0.0 1.2e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJW69917.1 - 1.1e-08 35.2 0.1 3.1e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 AJW69917.1 - 0.0006 19.4 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AJW69917.1 - 0.0015 18.6 0.1 0.056 13.5 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 AJW69917.1 - 0.031 13.9 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin zf-H2C2_2 PF13465.1 AJW69917.1 - 0.13 12.6 0.2 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double domain Copper-bind PF00127.15 AJW69918.1 - 8.8e-07 29.0 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW69918.1 - 0.00044 20.0 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Rad50_zn_hook PF04423.9 AJW69920.1 - 0.01 15.2 3.5 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif MTHFR_C PF12225.3 AJW69920.1 - 0.075 12.5 5.0 0.052 13.0 2.8 1.3 1 1 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal C1_1 PF00130.17 AJW69920.1 - 0.45 10.2 6.4 0.95 9.2 4.5 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1007 PF06226.8 AJW69921.1 - 0.041 13.6 0.2 0.041 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) Lactonase PF10282.4 AJW69922.1 - 6.2e-13 48.5 0.7 2e-07 30.4 0.2 3.6 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 AJW69922.1 - 3e-09 35.6 0.0 8.8e-05 20.9 0.0 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain DUF4221 PF13970.1 AJW69922.1 - 0.0016 17.7 1.7 2.3 7.4 0.0 3.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4221) SGL PF08450.7 AJW69922.1 - 0.011 15.1 0.4 2.2 7.5 0.1 3.0 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DUF1513 PF07433.6 AJW69922.1 - 0.038 12.8 0.1 1.8 7.4 0.0 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) FlaG PF03646.10 AJW69922.1 - 0.57 10.3 4.1 9.9 6.3 0.5 3.2 3 0 0 3 3 3 0 FlaG protein Astro_capsid PF03115.9 AJW69925.1 - 1.5 6.9 11.4 1.9 6.6 7.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Lipase_chap PF03280.9 AJW69925.1 - 2 7.8 8.7 0.096 12.2 2.4 1.5 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein Cu-oxidase_3 PF07732.10 AJW69926.1 - 1.2e-31 108.8 1.3 1e-30 105.9 0.0 2.8 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AJW69926.1 - 3e-30 104.5 8.1 1.9e-22 79.2 2.9 4.6 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 AJW69926.1 - 5.9e-14 52.2 0.1 2.2e-09 37.3 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 AJW69926.1 - 0.0077 16.1 0.0 12 5.8 0.0 3.5 3 0 0 3 3 3 1 Cupredoxin-like domain PLAT PF01477.18 AJW69926.1 - 0.061 13.7 0.3 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 PLAT/LH2 domain SoxE PF06525.6 AJW69926.1 - 0.066 12.4 0.7 0.42 9.8 0.0 2.3 2 0 0 2 2 2 0 Sulfocyanin (SoxE) Ferric_reduct PF01794.14 AJW69927.1 - 7.7e-09 35.7 9.5 7.7e-09 35.7 6.6 2.6 2 1 1 3 3 3 2 Ferric reductase like transmembrane component Ost4 PF10215.4 AJW69927.1 - 0.0052 16.2 0.3 0.022 14.2 0.2 2.1 1 0 0 1 1 1 1 Oligosaccaryltransferase Spermine_synth PF01564.12 AJW69928.1 - 3.5e-15 55.6 0.0 6.7e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 AJW69928.1 - 2.5e-05 24.8 0.0 5.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 AJW69928.1 - 8.3e-05 22.2 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_3 PF01596.12 AJW69928.1 - 0.002 17.2 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 AJW69928.1 - 0.0029 18.4 0.0 0.0067 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW69928.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW69928.1 - 0.0083 16.5 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJW69928.1 - 0.03 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NikR_C PF08753.6 AJW69929.1 - 1.2e-10 41.1 2.5 1.8e-10 40.5 1.7 1.3 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.16 AJW69929.1 - 2.4e-05 23.9 0.1 3.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF2191 PF09957.4 AJW69929.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2191) DUF1387 PF07139.6 AJW69929.1 - 0.038 13.5 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TroA PF01297.12 AJW69930.1 - 4.5e-79 265.3 0.6 5.1e-79 265.1 0.4 1.0 1 0 0 1 1 1 1 Periplasmic solute binding protein family AP_endonuc_2 PF01261.19 AJW69930.1 - 0.073 12.3 0.0 0.73 9.0 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel ABC_tran PF00005.22 AJW69931.1 - 2.1e-35 122.0 0.0 7.4e-35 120.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 AJW69931.1 - 1.9e-14 54.2 5.2 7.1e-13 49.1 3.6 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJW69931.1 - 4.8e-06 25.9 1.3 8.9e-05 21.8 0.9 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AJW69931.1 - 7.3e-06 25.4 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 AJW69931.1 - 2.1e-05 23.7 4.1 0.0035 16.4 0.4 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AJW69931.1 - 6.5e-05 23.3 4.0 0.00012 22.5 2.8 1.6 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 AJW69931.1 - 0.0014 18.5 0.1 0.032 14.1 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 AJW69931.1 - 0.0035 15.8 1.9 0.27 9.6 0.4 2.1 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AJW69931.1 - 0.0049 16.2 0.5 2.9 7.2 0.1 2.7 3 1 0 3 3 3 2 IstB-like ATP binding protein MMR_HSR1 PF01926.18 AJW69931.1 - 0.006 16.5 0.2 0.0086 16.0 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AJW69931.1 - 0.009 15.2 0.0 0.018 14.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 AJW69931.1 - 0.024 14.4 0.0 0.14 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 AJW69931.1 - 0.025 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 AJW69931.1 - 0.045 13.4 0.2 0.078 12.6 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 AJW69931.1 - 0.084 12.7 0.5 1.7 8.5 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AJW69931.1 - 0.093 12.1 0.9 1.1 8.6 0.2 2.2 1 1 2 3 3 3 0 AAA-like domain AAA_16 PF13191.1 AJW69931.1 - 0.11 12.5 0.2 0.74 9.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 AJW69931.1 - 0.13 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 AJW69931.1 - 0.14 12.2 0.2 0.54 10.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AJW69931.1 - 0.17 12.7 0.3 2 9.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC-3 PF00950.12 AJW69932.1 - 1e-62 211.7 37.2 1.2e-62 211.6 25.8 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.13 AJW69932.1 - 7.4e-06 25.0 33.0 2.1e-05 23.5 22.9 1.7 1 1 0 1 1 1 1 FecCD transport family SGL PF08450.7 AJW69933.1 - 2.7e-13 49.8 0.3 0.038 13.3 0.0 5.3 1 1 3 5 5 5 5 SMP-30/Gluconolaconase/LRE-like region CopD PF05425.8 AJW69933.1 - 3.8e-12 46.3 1.0 3.8e-12 46.3 0.7 2.4 2 0 0 2 2 2 1 Copper resistance protein D CopC PF04234.7 AJW69933.1 - 5.9e-11 42.8 0.0 1.8e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 CopC domain Reg_prop PF07494.6 AJW69933.1 - 0.00037 20.1 12.3 14 6.1 0.0 7.4 9 0 0 9 9 9 2 Two component regulator propeller YtkA PF13115.1 AJW69933.1 - 0.00075 19.8 0.0 0.0021 18.3 0.0 1.8 2 0 0 2 2 2 1 YtkA-like Big_3_4 PF13754.1 AJW69933.1 - 0.07 13.4 0.2 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) PPC PF04151.10 AJW69933.1 - 4.1 8.4 6.6 3.4 8.7 0.5 3.2 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain FlxA PF14282.1 AJW69934.1 - 0.047 13.6 0.4 0.074 13.0 0.3 1.2 1 0 0 1 1 1 0 FlxA-like protein Cupredoxin_1 PF13473.1 AJW69935.1 - 0.0017 18.2 0.0 0.0069 16.2 0.0 2.0 2 1 0 2 2 2 1 Cupredoxin-like domain DUF3561 PF12084.3 AJW69940.1 - 0.05 13.4 7.1 0.045 13.6 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3561) Phage_holin_2 PF04550.7 AJW69940.1 - 0.18 11.9 4.7 0.28 11.3 2.9 1.7 1 1 1 2 2 2 0 Phage holin family 2 HTH_24 PF13412.1 AJW69941.1 - 1.6e-14 53.0 0.1 2.6e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 AJW69941.1 - 1.6e-12 46.8 0.1 2.8e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family TrmB PF01978.14 AJW69941.1 - 4.6e-08 32.6 0.3 0.00055 19.5 0.2 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 AJW69941.1 - 1e-07 31.6 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain MarR PF01047.17 AJW69941.1 - 1.4e-07 31.0 0.0 0.0005 19.7 0.0 2.3 2 0 0 2 2 2 2 MarR family MarR_2 PF12802.2 AJW69941.1 - 1.5e-07 30.9 0.1 0.00014 21.4 0.0 2.3 2 0 0 2 2 2 2 MarR family HTH_29 PF13551.1 AJW69941.1 - 1e-05 25.6 0.0 0.065 13.3 0.0 2.2 1 1 1 2 2 2 2 Winged helix-turn helix HTH_34 PF13601.1 AJW69941.1 - 1.6e-05 24.8 0.1 0.029 14.3 0.0 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain HTH_IclR PF09339.5 AJW69941.1 - 1.8e-05 24.2 0.0 0.074 12.6 0.0 2.2 2 0 0 2 2 2 2 IclR helix-turn-helix domain Rrf2 PF02082.15 AJW69941.1 - 3.5e-05 23.8 0.2 0.0041 17.1 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulator HTH_45 PF14947.1 AJW69941.1 - 0.00011 21.9 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix FeoC PF09012.5 AJW69941.1 - 0.0059 16.2 0.1 2.1 8.1 0.0 2.2 2 0 0 2 2 2 1 FeoC like transcriptional regulator Fe_dep_repress PF01325.14 AJW69941.1 - 0.0095 15.8 0.2 0.083 12.8 0.0 2.2 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_38 PF13936.1 AJW69941.1 - 0.014 14.9 0.0 0.15 11.6 0.0 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.11 AJW69941.1 - 0.015 14.8 0.1 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 LexA DNA binding domain HTH_40 PF14493.1 AJW69941.1 - 0.016 15.4 0.0 0.95 9.7 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain RP-C PF03428.8 AJW69941.1 - 0.062 12.7 0.0 0.14 11.6 0.0 1.6 1 1 1 2 2 2 0 Replication protein C N-terminal domain HTH_Crp_2 PF13545.1 AJW69941.1 - 0.08 12.7 0.0 14 5.5 0.0 2.5 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain DUF2250 PF10007.4 AJW69941.1 - 0.1 12.4 0.8 4.6 7.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) PCI PF01399.22 AJW69941.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 PCI domain RPA_C PF08784.6 AJW69941.1 - 0.13 12.6 0.1 19 5.7 0.0 2.2 2 0 0 2 2 2 0 Replication protein A C terminal AntA PF08346.7 AJW69942.1 - 0.06 13.5 1.0 0.12 12.5 0.2 1.8 1 1 0 1 1 1 0 AntA/AntB antirepressor CHRD PF07452.7 AJW69943.1 - 0.0004 20.9 0.0 0.00073 20.1 0.0 1.4 1 1 0 1 1 1 1 CHRD domain Ponericin PF07442.6 AJW69943.1 - 0.45 10.3 3.4 2.6 7.9 0.9 2.5 2 0 0 2 2 2 0 Ponericin Rhomboid PF01694.17 AJW69944.1 - 1.1e-30 106.6 18.0 1.1e-30 106.6 12.5 1.5 2 0 0 2 2 2 1 Rhomboid family Tautomerase PF01361.16 AJW69945.1 - 2.4e-14 52.6 0.0 2.5e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 AJW69945.1 - 1.7e-08 34.3 0.0 1.8e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme DUF1904 PF08921.6 AJW69945.1 - 0.0081 16.1 0.0 0.0081 16.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1904) Tautomerase_3 PF14832.1 AJW69945.1 - 0.02 14.9 0.0 0.021 14.8 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme DUF1906 PF08924.6 AJW69945.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) CN_hydrolase PF00795.17 AJW69946.1 - 1.7e-30 105.7 0.0 2.3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pox_D3 PF04580.8 AJW69946.1 - 0.023 13.9 1.8 0.038 13.1 1.3 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-C4_Topoisom PF01396.14 AJW69947.1 - 3e-07 29.8 7.6 3e-06 26.6 0.8 2.7 2 1 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.7 AJW69947.1 - 0.096 12.3 10.0 2.7 7.7 1.3 3.5 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.1 AJW69947.1 - 0.22 11.8 5.6 0.55 10.5 0.4 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Thiolase_C PF02803.13 AJW69948.1 - 3.5e-12 45.8 1.0 6e-10 38.6 0.0 3.3 2 2 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 AJW69948.1 - 1e-07 31.2 0.0 9e-07 28.1 0.0 2.3 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 AJW69948.1 - 0.0056 16.1 0.3 0.069 12.6 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AJW69948.1 - 0.027 14.1 0.2 2 8.1 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 AJW69948.1 - 0.037 13.8 2.2 1.7 8.5 0.0 3.5 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain DUF35 PF01796.12 AJW69949.1 - 3.7e-10 39.8 0.1 5.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain zinc_ribbon_2 PF13240.1 AJW69949.1 - 0.00046 19.5 3.5 0.00083 18.7 2.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DUF35_N PF12172.3 AJW69949.1 - 0.00051 19.8 0.1 0.00077 19.2 0.1 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2082 PF09855.4 AJW69949.1 - 0.027 14.3 0.5 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DZR PF12773.2 AJW69949.1 - 0.045 13.5 0.6 0.078 12.8 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon PHF5 PF03660.9 AJW69949.1 - 0.073 13.1 0.3 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 PHF5-like protein TFIIS_C PF01096.13 AJW69949.1 - 0.13 11.9 2.3 8 6.1 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Nudix_N_2 PF14803.1 AJW69949.1 - 0.58 9.9 3.0 14 5.4 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.1 AJW69949.1 - 0.63 9.3 2.9 2 7.7 2.0 1.9 1 1 1 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.6 AJW69949.1 - 0.69 10.0 5.3 12 6.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-CCHC_4 PF14392.1 AJW69949.1 - 3 7.5 5.1 17 5.1 0.5 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.1 AJW69950.1 - 0.00014 20.9 2.1 0.051 12.7 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJW69950.1 - 0.00042 19.7 3.9 0.043 13.3 0.2 2.2 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.2 AJW69950.1 - 0.00065 19.4 1.6 0.0011 18.7 1.1 1.4 1 1 0 1 1 1 1 Double zinc ribbon TF_Zn_Ribbon PF08271.7 AJW69950.1 - 0.00068 18.9 0.8 0.19 11.0 0.1 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding zf-DNA_Pol PF08996.5 AJW69950.1 - 0.0023 17.3 1.1 0.0023 17.3 0.8 1.0 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-C4_Topoisom PF01396.14 AJW69950.1 - 0.0046 16.4 3.6 0.12 11.8 0.2 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Chordopox_RPO7 PF05864.7 AJW69950.1 - 0.0061 16.6 0.5 0.1 12.7 0.4 2.1 1 1 1 2 2 2 2 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Prok-RING_1 PF14446.1 AJW69950.1 - 0.0061 16.2 1.2 0.38 10.5 0.1 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.3 AJW69950.1 - 0.0065 16.4 1.2 0.019 14.9 0.1 1.8 1 1 1 2 2 2 1 FANCL C-terminal domain zf-LITAF-like PF10601.4 AJW69950.1 - 0.008 16.0 2.1 0.23 11.3 0.1 2.2 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain zf-Di19 PF05605.7 AJW69950.1 - 0.0092 16.0 0.2 0.018 15.1 0.1 1.5 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-IS66 PF13005.2 AJW69950.1 - 0.0094 15.9 1.0 0.39 10.7 0.1 2.1 2 0 0 2 2 2 1 zinc-finger binding domain of transposase IS66 Zn-ribbon_8 PF09723.5 AJW69950.1 - 0.012 15.5 2.8 0.074 13.0 1.9 1.9 1 1 0 1 1 1 0 Zinc ribbon domain LIM PF00412.17 AJW69950.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 LIM domain zinc_ribbon_4 PF13717.1 AJW69950.1 - 0.013 15.1 2.2 0.73 9.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF4428 PF14471.1 AJW69950.1 - 0.013 15.2 3.7 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zinc_ribbon_5 PF13719.1 AJW69950.1 - 0.015 14.9 2.7 0.68 9.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.8 AJW69950.1 - 0.017 14.8 2.0 0.33 10.7 1.4 2.0 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.1 AJW69950.1 - 0.017 14.7 2.1 0.028 14.0 1.4 1.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIB PF13453.1 AJW69950.1 - 0.019 14.1 0.6 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C2H2 PF00096.21 AJW69950.1 - 0.019 15.2 2.1 2.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type HypA PF01155.14 AJW69950.1 - 0.034 13.8 0.6 0.049 13.3 0.4 1.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 AJW69950.1 - 0.035 13.9 1.3 0.63 9.8 0.0 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AJW69950.1 - 0.044 13.2 1.1 1.5 8.3 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ISL3 PF14690.1 AJW69950.1 - 0.049 13.6 1.0 5.6 7.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rad50_zn_hook PF04423.9 AJW69950.1 - 0.049 13.1 0.7 0.066 12.6 0.4 1.6 1 1 0 1 1 1 0 Rad50 zinc hook motif Sgf11 PF08209.6 AJW69950.1 - 0.064 12.5 0.9 2.5 7.5 0.1 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_4 PF13894.1 AJW69950.1 - 0.066 13.5 0.3 11 6.5 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger YhfH PF14149.1 AJW69950.1 - 0.068 12.9 5.3 2.8 7.8 0.8 2.2 2 0 0 2 2 2 0 YhfH-like protein Elf1 PF05129.8 AJW69950.1 - 0.075 12.7 2.1 3.2 7.5 0.2 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-dskA_traR PF01258.12 AJW69950.1 - 0.081 12.6 1.3 3.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger UPF0547 PF10571.4 AJW69950.1 - 0.091 12.4 0.4 0.76 9.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FpoO PF10621.4 AJW69950.1 - 0.092 12.8 0.5 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Nudix_N_2 PF14803.1 AJW69950.1 - 0.1 12.2 0.9 3.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Nudix N-terminal zf-FPG_IleRS PF06827.9 AJW69950.1 - 0.11 12.2 0.3 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DiS_P_DiS PF06750.8 AJW69950.1 - 0.11 12.3 1.0 0.53 10.1 0.7 1.8 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-CHY PF05495.7 AJW69950.1 - 0.11 12.6 0.9 0.14 12.3 0.6 1.1 1 0 0 1 1 1 0 CHY zinc finger DUF329 PF03884.9 AJW69950.1 - 0.11 12.0 0.9 1.9 8.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Lar_restr_allev PF14354.1 AJW69950.1 - 0.13 12.6 1.1 0.32 11.3 0.8 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar Stc1 PF12898.2 AJW69950.1 - 0.13 12.3 1.2 0.2 11.7 0.8 1.4 1 1 0 1 1 1 0 Stc1 domain TFIIS_C PF01096.13 AJW69950.1 - 0.14 11.8 2.9 5.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc-ribbons_6 PF07191.7 AJW69950.1 - 0.16 11.7 1.4 5.2 6.9 0.1 2.1 1 1 0 2 2 2 0 zinc-ribbons DNA_ligase_ZBD PF03119.11 AJW69950.1 - 0.16 11.6 0.4 0.16 11.6 0.3 1.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ogr_Delta PF04606.7 AJW69950.1 - 0.17 11.5 0.7 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1 PF03811.8 AJW69950.1 - 0.19 11.2 1.2 5.8 6.5 0.1 2.1 2 0 0 2 2 2 0 InsA N-terminal domain zf-NADH-PPase PF09297.6 AJW69950.1 - 0.23 10.9 4.5 3.6 7.1 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ADK_lid PF05191.9 AJW69950.1 - 0.32 10.6 5.2 5.4 6.7 3.6 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid T4_baseplate PF12322.3 AJW69950.1 - 0.35 10.0 2.8 2.6 7.2 0.1 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Zn_ribbon_recom PF13408.1 AJW69950.1 - 0.41 10.9 3.9 2.9 8.2 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain CpXC PF14353.1 AJW69950.1 - 0.46 10.4 2.5 19 5.2 1.8 2.1 1 1 0 1 1 1 0 CpXC protein OrfB_Zn_ribbon PF07282.6 AJW69950.1 - 0.55 9.9 3.9 2.8 7.6 0.2 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF1610 PF07754.6 AJW69950.1 - 4.1 7.6 6.0 12 6.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) NRDD PF13597.1 AJW69951.1 - 4.9e-21 74.4 0.0 1.4e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.2 AJW69951.1 - 8.3e-10 38.3 0.0 2.4e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.11 AJW69951.1 - 2.8e-07 30.8 3.8 2.9e-07 30.8 0.0 3.0 4 0 0 4 4 4 1 ATP cone domain zf-C3HC4_3 PF13920.1 AJW69951.1 - 0.18 11.4 0.2 0.33 10.6 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribonuc_red_lgC PF02867.10 AJW69952.1 - 3.1e-152 507.8 0.0 6e-152 506.9 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AJW69952.1 - 1.7e-31 107.8 0.0 4e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AJW69952.1 - 1.1e-23 83.4 0.6 2.8e-23 82.1 0.4 1.8 1 0 0 1 1 1 1 ATP cone domain Glyco_hydro_35 PF01301.14 AJW69953.1 - 0.00024 20.5 0.0 0.00082 18.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 AJW69953.1 - 0.0065 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 AJW69953.1 - 0.074 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 NapD PF03927.8 AJW69953.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 NapD protein EMG1 PF03587.9 AJW69954.1 - 2.6e-43 147.6 0.1 2.9e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Rpr2 PF04032.11 AJW69955.1 - 4e-18 65.0 1.4 4.7e-18 64.8 1.0 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Sec23_Sec24 PF04810.10 AJW69955.1 - 0.0089 15.5 1.6 1.1 8.9 0.1 2.2 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger C1_1 PF00130.17 AJW69955.1 - 0.086 12.5 0.7 0.15 11.8 0.5 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PapD-like PF14874.1 AJW69955.1 - 0.09 12.7 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 Flagellar-associated PapD-like Cys_rich_KTR PF14205.1 AJW69955.1 - 0.7 9.4 3.5 1.5 8.3 0.3 2.4 2 0 0 2 2 2 0 Cysteine-rich KTR HATPase_c PF02518.21 AJW69956.1 - 6.9e-20 70.8 0.2 1.3e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 AJW69956.1 - 3.7e-17 62.5 0.0 1.1e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain HAMP PF00672.20 AJW69956.1 - 5.5e-16 58.5 0.0 6.8e-15 55.0 0.0 2.7 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.1 AJW69956.1 - 3.1e-11 42.8 0.6 1.4e-10 40.7 0.4 2.1 1 0 0 1 1 1 1 GHKL domain HisKA PF00512.20 AJW69956.1 - 3.5e-11 42.9 0.4 1.3e-10 41.0 0.3 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 AJW69956.1 - 2.8e-09 36.7 0.0 6.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 AJW69956.1 - 1.9e-06 27.8 0.0 4.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 AJW69956.1 - 5.8e-05 22.7 0.3 0.00019 21.0 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW69956.1 - 0.0015 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_4 PF08448.5 AJW69956.1 - 0.0031 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 AJW69956.1 - 0.011 15.6 0.0 0.035 13.9 0.0 1.9 1 0 0 1 1 1 0 PAS domain 4HB_MCP_1 PF12729.2 AJW69956.1 - 0.32 10.3 23.3 0.0087 15.4 6.6 4.1 3 2 0 3 3 3 0 Four helix bundle sensory module for signal transduction Response_reg PF00072.19 AJW69957.1 - 2e-16 59.9 0.1 2.2e-16 59.8 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF3284 PF11687.3 AJW69957.1 - 0.054 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) Ribosomal_S19e PF01090.14 AJW69958.1 - 2.7e-50 169.4 0.0 3e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e dsDNA_bind PF01984.15 AJW69959.1 - 9e-24 83.5 1.1 1e-23 83.3 0.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain FliT PF05400.8 AJW69959.1 - 0.52 10.7 3.1 0.35 11.2 0.8 1.7 1 1 1 2 2 2 0 Flagellar protein FliT ADH_zinc_N PF00107.21 AJW69960.1 - 2.9e-29 101.2 0.0 7.2e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AJW69960.1 - 1.1e-21 76.5 0.1 1.8e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AJW69960.1 - 4.1e-17 63.2 0.0 8.9e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HpcH_HpaI PF03328.9 AJW69961.1 - 1.6e-47 161.2 0.0 1.9e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 AJW69961.1 - 1.5e-17 63.5 0.1 1.7e-08 33.7 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 AJW69961.1 - 0.0051 15.4 0.2 0.0065 15.1 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Ribosomal_S19e PF01090.14 AJW69961.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S19e Response_reg PF00072.19 AJW69962.1 - 1.9e-18 66.5 0.2 2.1e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF2608 PF11019.3 AJW69962.1 - 0.0043 16.0 0.1 0.058 12.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) TrkA_N PF02254.13 AJW69962.1 - 0.0092 15.9 0.8 0.47 10.4 0.6 2.9 1 1 0 1 1 1 1 TrkA-N domain B12-binding PF02310.14 AJW69962.1 - 0.043 13.6 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain NKWYS PF10364.4 AJW69962.1 - 0.048 13.3 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein DUF356 PF04009.7 AJW69962.1 - 0.049 13.6 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF356) DUF4415 PF14384.1 AJW69963.1 - 0.086 13.0 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4415) TPR_11 PF13414.1 AJW69964.1 - 5.7e-32 109.1 12.6 2.7e-13 49.3 0.1 3.7 1 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 AJW69964.1 - 2.9e-25 86.7 11.8 7.1e-08 31.7 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 AJW69964.1 - 4.3e-19 66.8 3.6 4.5e-06 26.1 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 AJW69964.1 - 1.4e-15 56.9 2.7 7e-06 25.8 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AJW69964.1 - 1.2e-13 50.0 7.9 4.4e-05 23.3 0.0 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 AJW69964.1 - 2.7e-13 49.2 0.0 0.056 14.0 0.0 5.2 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 AJW69964.1 - 1.6e-12 47.6 0.0 2.4e-06 28.0 0.0 3.2 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 AJW69964.1 - 1.4e-11 43.2 1.6 0.025 14.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AJW69964.1 - 1e-10 41.8 3.1 0.0001 22.5 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 AJW69964.1 - 2.7e-10 39.9 0.0 2.6e-05 23.9 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AJW69964.1 - 2.2e-08 33.2 17.4 0.2 11.5 0.1 5.9 3 1 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 AJW69964.1 - 7.9e-08 32.3 8.2 6.7e-05 22.9 0.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 AJW69964.1 - 2.5e-07 30.4 2.2 0.45 10.5 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJW69964.1 - 3.3e-06 26.8 8.8 0.97 9.3 0.1 5.1 2 2 2 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 AJW69964.1 - 7.8e-06 24.9 1.5 1.6e-05 23.9 0.1 1.9 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 AJW69964.1 - 0.00017 21.8 2.0 6.6 7.4 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 AJW69964.1 - 0.00024 20.9 1.8 0.085 12.7 0.0 3.9 2 1 2 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 AJW69964.1 - 0.00064 18.8 0.2 0.0024 16.9 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat PPTA PF01239.17 AJW69964.1 - 0.0019 17.4 0.6 0.22 10.9 0.0 2.7 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat TPR_20 PF14561.1 AJW69964.1 - 0.0029 17.6 0.2 4.6 7.4 0.1 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 AJW69964.1 - 0.0074 16.5 0.4 0.24 11.6 0.0 2.7 1 1 1 2 2 2 1 Alkyl sulfatase dimerisation Coatomer_E PF04733.9 AJW69964.1 - 0.013 14.7 4.4 0.29 10.2 0.1 2.2 1 1 1 2 2 2 0 Coatomer epsilon subunit DUF3856 PF12968.2 AJW69964.1 - 0.025 14.4 0.1 0.83 9.4 0.0 3.2 1 1 3 4 4 4 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 AJW69964.1 - 0.063 12.9 0.9 3.1 7.4 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF627) Cas_Cas02710 PF09670.5 AJW69964.1 - 0.082 11.5 1.3 0.14 10.7 0.8 1.4 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) TPR_3 PF07720.7 AJW69964.1 - 0.17 11.7 0.1 0.17 11.7 0.0 2.7 4 0 0 4 4 2 0 Tetratricopeptide repeat SPOB_a PF14689.1 AJW69964.1 - 0.66 9.5 8.5 6.5 6.4 0.2 4.0 4 1 1 5 5 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain CLTH PF10607.4 AJW69964.1 - 0.67 9.6 4.4 1 9.0 1.1 2.3 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Lum_binding PF00677.12 AJW69965.1 - 1.4e-46 156.2 12.9 8.1e-27 92.9 1.3 2.0 2 0 0 2 2 2 2 Lumazine binding domain DHBP_synthase PF00926.14 AJW69966.1 - 3.4e-69 231.9 0.0 3.8e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PAF-AH_p_II PF03403.8 AJW69966.1 - 0.075 11.3 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PCP_red PF08369.5 AJW69966.1 - 0.14 12.0 0.1 1 9.2 0.0 2.4 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit DMRL_synthase PF00885.14 AJW69967.1 - 2.5e-33 114.7 0.8 2.7e-33 114.6 0.5 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF3356 PF11836.3 AJW69967.1 - 0.059 13.1 0.1 2.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3356) Senescence PF06911.7 AJW69967.1 - 0.062 12.9 0.1 0.091 12.4 0.1 1.2 1 0 0 1 1 1 0 Senescence-associated protein GGDN PF05165.7 AJW69968.1 - 4.8e-48 163.3 0.0 6.2e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 GGDN family Guanylate_cyc PF00211.15 AJW69968.1 - 0.00056 19.3 0.1 0.0011 18.3 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NOG1 PF06858.9 AJW69968.1 - 0.073 12.9 0.4 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) UFC1 PF08694.6 AJW69968.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Amidohydro_1 PF01979.15 AJW69969.1 - 3.3e-29 102.6 0.2 2.5e-18 66.8 0.1 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 AJW69969.1 - 6.5e-11 41.8 0.1 2.2e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 AJW69969.1 - 1.1e-10 41.9 0.0 9.9e-05 22.4 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 AJW69969.1 - 8.4e-06 25.2 0.0 0.0036 16.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Orthopox_B11R PF07033.6 AJW69969.1 - 4 6.9 5.8 5.2 6.6 0.0 3.4 4 0 0 4 4 4 0 Orthopoxvirus B11R protein RibD_C PF01872.12 AJW69970.1 - 4.6e-50 170.0 0.1 5.1e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 RibD C-terminal domain SWIB PF02201.13 AJW69971.1 - 0.0068 16.0 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain Pox_Ag35 PF03286.9 AJW69971.1 - 0.86 9.0 6.7 0.86 9.0 4.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Glycoprotein_G PF00802.14 AJW69971.1 - 7.7 5.5 10.6 7.4 5.6 7.3 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Hemerythrin PF01814.18 AJW69972.1 - 1e-09 38.6 0.2 5.8e-09 36.2 0.0 2.2 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain IZUMO PF15005.1 AJW69972.1 - 0.04 13.9 2.5 0.21 11.6 0.4 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion Methyltransf_4 PF02390.12 AJW69972.1 - 0.066 12.2 1.5 0.083 11.9 0.5 1.6 2 0 0 2 2 2 0 Putative methyltransferase 4HB_MCP_1 PF12729.2 AJW69972.1 - 0.079 12.2 3.9 0.034 13.4 1.0 1.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Nucleoplasmin PF03066.10 AJW69973.1 - 1.4 8.4 6.4 1.2 8.6 4.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Aldedh PF00171.17 AJW69974.1 - 1.6e-144 481.7 0.1 1.8e-144 481.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2365 PF10157.4 AJW69975.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Pyridoxal_deC PF00282.14 AJW69975.1 - 0.083 11.3 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain TFIIE_alpha PF02002.12 AJW69976.1 - 1.6e-18 66.0 1.3 2.8e-18 65.3 0.9 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit SAM_decarbox PF01536.11 AJW69976.1 - 0.024 13.2 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase TrmB PF01978.14 AJW69976.1 - 0.034 13.8 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sushi_2 PF09014.5 AJW69976.1 - 0.057 13.1 0.5 0.094 12.4 0.3 1.4 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain RRN7 PF11781.3 AJW69976.1 - 0.091 12.2 0.4 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Sigma70_r3 PF04539.11 AJW69976.1 - 0.14 12.0 1.2 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 Phe_tRNA-synt_N PF02912.13 AJW69976.1 - 0.22 11.2 4.2 12 5.6 0.5 3.0 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Zn_ribbon_recom PF13408.1 AJW69976.1 - 0.3 11.3 0.1 0.3 11.3 0.1 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2346 PF09803.4 AJW69976.1 - 2 8.3 4.9 0.26 11.1 0.6 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) Trm56 PF01994.11 AJW69977.1 - 2.8e-50 169.1 0.4 4e-50 168.5 0.2 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SpoU_methylase PF00588.14 AJW69977.1 - 2e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.1 AJW69977.1 - 0.0085 15.2 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP ABC_transp_aux PF09822.4 AJW69977.1 - 0.04 13.3 0.0 0.063 12.7 0.0 1.4 1 1 0 1 1 1 0 ABC-type uncharacterized transport system Condensin2nSMC PF12422.3 AJW69977.1 - 0.063 13.0 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit MMR_HSR1 PF01926.18 AJW69978.1 - 9.3e-19 67.4 0.3 2.8e-18 65.9 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AJW69978.1 - 2e-09 36.8 0.9 3.6e-09 36.1 0.6 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP-bdg_N PF13167.1 AJW69978.1 - 9.2e-09 35.3 1.2 2.1e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 GTP-binding GTPase N-terminal GTP_EFTU PF00009.22 AJW69978.1 - 1.8e-06 27.5 3.6 4.3e-05 23.0 2.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 AJW69978.1 - 0.00013 21.3 3.0 0.00026 20.2 2.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 AJW69978.1 - 0.00013 22.4 0.3 0.0013 19.2 0.1 2.6 2 1 1 3 3 3 1 Miro-like protein PduV-EutP PF10662.4 AJW69978.1 - 0.00035 20.0 4.8 0.0045 16.4 3.4 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 AJW69978.1 - 0.00063 19.1 1.9 0.0023 17.3 1.3 1.9 1 1 0 1 1 1 1 Ras family DUF258 PF03193.11 AJW69978.1 - 0.0015 17.6 2.0 0.0048 16.1 0.3 2.4 1 1 1 2 2 2 1 Protein of unknown function, DUF258 Trans_reg_C PF00486.23 AJW69978.1 - 0.033 14.0 0.5 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal ATP_bind_1 PF03029.12 AJW69978.1 - 0.051 13.0 2.0 0.15 11.5 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 AJW69978.1 - 0.099 12.9 1.6 0.25 11.6 0.4 2.4 2 1 1 3 3 3 0 ABC transporter Dynamin_N PF00350.18 AJW69978.1 - 0.11 12.2 4.2 1.5 8.6 2.9 2.8 1 1 0 1 1 1 0 Dynamin family AAA PF00004.24 AJW69978.1 - 0.11 12.6 3.3 7.2 6.8 0.0 2.9 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 AJW69978.1 - 0.36 10.2 3.6 4.1 6.8 0.1 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Syntaxin PF00804.20 AJW69978.1 - 3.7 7.7 10.2 22 5.2 0.1 3.0 3 1 0 3 3 2 0 Syntaxin PhoU PF01895.14 AJW69979.1 - 3.7e-28 97.8 14.6 1.6e-19 70.0 1.2 2.5 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 AJW69979.1 - 4e-08 32.8 0.1 2.2e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Antidote-toxin recognition MazE YbjQ_1 PF01906.12 AJW69979.1 - 0.096 13.1 0.8 0.32 11.4 0.1 2.2 2 0 0 2 2 2 0 Putative heavy-metal-binding CorA PF01544.13 AJW69979.1 - 1.5 7.8 5.8 0.41 9.6 0.8 2.0 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein PUA PF01472.15 AJW69980.1 - 7.5e-10 38.3 0.2 2.4e-09 36.8 0.2 1.8 2 0 0 2 2 2 1 PUA domain TGT_C2 PF14810.1 AJW69980.1 - 3.9e-09 36.2 0.0 6.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase NAC PF01849.13 AJW69981.1 - 3e-15 55.4 1.4 5.2e-15 54.7 0.9 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 AJW69981.1 - 4.3e-06 26.3 0.3 4.3e-06 26.3 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 AJW69981.1 - 0.01 15.3 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain Cytidylate_kin2 PF13189.1 AJW69981.1 - 0.039 13.8 2.2 0.086 12.7 0.1 2.0 2 1 0 2 2 2 0 Cytidylate kinase-like family FdtA PF05523.6 AJW69981.1 - 0.059 12.8 0.1 0.088 12.3 0.1 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal Gpi16 PF04113.9 AJW69981.1 - 0.11 10.4 0.2 0.13 10.2 0.2 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component ATP-synt_DE PF00401.15 AJW69981.1 - 0.21 11.5 2.0 0.38 10.6 1.4 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Copper-bind PF00127.15 AJW69982.1 - 4.5e-05 23.5 0.1 4.5e-05 23.5 0.1 2.9 1 1 2 3 3 3 1 Copper binding proteins, plastocyanin/azurin family CP_ATPgrasp_1 PF04174.8 AJW69982.1 - 0.031 12.9 0.5 0.037 12.6 0.4 1.1 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Cupredoxin_1 PF13473.1 AJW69982.1 - 0.04 13.8 0.0 0.086 12.7 0.0 1.7 1 1 0 1 1 1 0 Cupredoxin-like domain COG6 PF06419.6 AJW69983.1 - 0.00039 18.6 4.9 0.00047 18.4 3.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 V-ATPase_G PF03179.10 AJW69983.1 - 0.0016 18.7 3.9 0.002 18.3 2.7 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Phage_Mu_Gam PF07352.7 AJW69983.1 - 0.0056 16.2 3.5 0.0073 15.8 2.4 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein EVC2_like PF12297.3 AJW69983.1 - 0.008 14.8 1.3 0.0085 14.7 0.9 1.1 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein Mitofilin PF09731.4 AJW69983.1 - 0.025 13.2 6.7 0.028 13.0 4.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CsoSCA PF08936.5 AJW69983.1 - 0.027 12.8 1.7 0.032 12.5 1.2 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase DUF883 PF05957.8 AJW69983.1 - 0.043 14.2 5.0 1.3 9.4 0.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 AJW69983.1 - 0.044 13.8 6.1 0.064 13.3 4.2 1.3 1 0 0 1 1 1 0 DivIVA protein DUF972 PF06156.8 AJW69983.1 - 0.052 13.9 4.2 0.071 13.4 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) RmuC PF02646.11 AJW69983.1 - 0.059 12.2 3.5 0.07 11.9 1.9 1.4 1 1 1 2 2 2 0 RmuC family DUF948 PF06103.6 AJW69983.1 - 0.061 13.1 3.8 0.15 11.9 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4071 PF13281.1 AJW69983.1 - 0.092 11.5 2.8 0.11 11.3 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Reo_sigmaC PF04582.7 AJW69983.1 - 0.094 11.8 5.6 0.11 11.6 3.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Phasin PF05597.6 AJW69983.1 - 0.13 12.0 7.2 1.7 8.4 1.9 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FlaC_arch PF05377.6 AJW69983.1 - 0.14 12.0 2.9 1.3 8.9 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 AJW69983.1 - 0.28 11.4 5.0 0.96 9.7 3.4 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ThylakoidFormat PF11264.3 AJW69983.1 - 0.34 10.5 4.3 0.34 10.4 3.0 1.0 1 0 0 1 1 1 0 Thylakoid formation protein Spc24 PF08286.6 AJW69983.1 - 0.34 10.6 7.3 1.3 8.7 5.1 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Sox_N PF12444.3 AJW69983.1 - 0.39 11.8 2.1 0.65 11.1 1.4 1.6 1 1 0 1 1 1 0 Sox developmental protein N terminal ATP-synt_B PF00430.13 AJW69983.1 - 0.81 9.4 9.6 1.5 8.6 6.7 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Pup PF05639.6 AJW69983.1 - 0.85 10.1 5.2 0.83 10.2 0.9 2.2 1 1 1 2 2 2 0 Pup-like protein Syntaxin PF00804.20 AJW69983.1 - 1.7 8.8 8.1 2.2 8.4 5.6 1.1 1 0 0 1 1 1 0 Syntaxin HSCB_C PF07743.8 AJW69983.1 - 3.5 8.1 6.7 13 6.3 0.9 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF460 PF04312.8 AJW69984.1 - 0.0055 16.2 0.0 0.0092 15.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF460) RPA_interact_C PF14768.1 AJW69985.1 - 0.095 13.1 5.6 7.6 7.0 1.0 2.6 1 1 1 2 2 2 0 Replication protein A interacting C-terminal Eapp_C PF10238.4 AJW69985.1 - 0.12 12.2 7.9 0.17 11.8 5.5 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Cys_rich_CPCC PF14206.1 AJW69985.1 - 0.12 11.9 2.8 0.18 11.4 0.2 2.4 2 0 0 2 2 2 0 Cysteine-rich CPCC C1_1 PF00130.17 AJW69985.1 - 0.25 11.1 10.8 0.57 9.9 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 AJW69985.1 - 0.58 10.0 6.3 3.1 7.6 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon Chlam_vir PF05475.6 AJW69986.1 - 0.084 11.9 0.1 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D UbiD PF01977.11 AJW69987.1 - 5e-103 344.6 0.0 5.7e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4HBT PF03061.17 AJW69988.1 - 4.8e-16 58.6 0.1 6.6e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 AJW69988.1 - 0.00086 18.6 0.1 0.0014 17.9 0.1 1.3 1 0 0 1 1 1 1 MaoC like domain DUF4442 PF14539.1 AJW69988.1 - 0.041 13.8 0.3 0.8 9.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4442) CTX_RstB PF07459.6 AJW69988.1 - 0.056 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 CTX phage RstB protein ERp29 PF07749.7 AJW69989.1 - 0.00012 22.6 2.1 0.43 11.2 0.0 2.2 2 0 0 2 2 2 2 Endoplasmic reticulum protein ERp29, C-terminal domain SnoaL PF07366.7 AJW69989.1 - 0.011 15.3 0.3 0.027 14.0 0.2 1.7 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase DDE_Tnp_ISL3 PF01610.12 AJW69989.1 - 0.016 14.8 7.1 0.29 10.6 0.3 2.3 1 1 1 2 2 2 0 Transposase Moulting_cycle PF04870.11 AJW69989.1 - 0.022 13.8 8.9 0.069 12.2 2.2 2.0 1 1 1 2 2 2 0 Moulting cycle CDC37_C PF08564.5 AJW69989.1 - 0.029 14.2 1.9 1.4 8.7 0.0 2.9 1 1 1 2 2 2 0 Cdc37 C terminal domain ATP-synt_G PF04718.10 AJW69989.1 - 0.067 13.8 3.3 0.12 13.0 0.7 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit YkyA PF10368.4 AJW69989.1 - 0.11 11.8 6.3 0.14 11.5 1.4 2.1 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein FragX_IP PF05994.6 AJW69989.1 - 0.13 10.0 3.3 0.15 9.8 2.3 1.2 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Transposase_mut PF00872.13 AJW69989.1 - 0.18 10.3 3.8 0.25 9.8 2.6 1.3 1 1 0 1 1 1 0 Transposase, Mutator family Phasin PF05597.6 AJW69989.1 - 0.22 11.2 2.8 0.3 10.8 0.9 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Phasin_2 PF09361.5 AJW69989.1 - 0.48 10.4 7.6 3 7.9 2.7 2.4 1 1 1 2 2 2 0 Phasin protein Sec10 PF07393.6 AJW69989.1 - 0.66 8.0 8.3 0.75 7.8 5.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Mating_N PF12731.2 AJW69989.1 - 0.71 9.7 5.9 2.3 8.1 1.5 2.9 1 1 1 2 2 2 0 Mating-type protein beta 1 DUF1104 PF06518.6 AJW69989.1 - 0.75 9.9 7.8 3.5 7.8 1.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1104) DASH_Dad2 PF08654.5 AJW69989.1 - 0.76 9.7 6.1 4.9 7.2 4.0 2.5 1 1 0 1 1 1 0 DASH complex subunit Dad2 U5_2-snRNA_bdg PF10597.4 AJW69989.1 - 1.3 8.5 5.7 1.2 8.7 1.3 2.0 1 1 1 2 2 2 0 U5-snRNA binding site 2 of PrP8 Tape_meas_lam_C PF09718.5 AJW69989.1 - 1.7 8.6 11.5 1.8 8.5 0.5 3.0 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CMAS PF02353.15 AJW69989.1 - 1.7 7.6 9.8 1.6 7.7 1.6 2.2 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase Colicin-DNase PF12639.2 AJW69989.1 - 2.2 8.5 6.1 15 5.8 4.2 2.2 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin MbeD_MobD PF04899.7 AJW69989.1 - 3.9 7.4 12.9 0.09 12.6 2.8 2.6 1 1 1 3 3 3 0 MbeD/MobD like PBD PF00786.23 AJW69989.1 - 4.5 7.7 9.7 9.5 6.7 0.4 3.7 1 1 2 3 3 3 0 P21-Rho-binding domain DUF2094 PF09867.4 AJW69989.1 - 4.8 7.0 7.6 7.8 6.3 1.3 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2094) DUF4298 PF14131.1 AJW69989.1 - 6.9 6.6 11.8 7.2 6.5 1.3 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4298) 4HB_MCP_1 PF12729.2 AJW69989.1 - 7.3 5.9 9.9 1.3 8.3 2.5 2.1 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DUF3080 PF11279.3 AJW69989.1 - 7.5 5.5 10.3 13 4.7 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) OppC_N PF12911.2 AJW69990.1 - 0.075 12.4 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2357 PF09823.4 AJW69991.1 - 0.012 14.7 3.4 0.014 14.5 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) LktC PF06261.6 AJW69991.1 - 0.025 14.2 1.8 0.029 14.0 0.6 1.5 1 1 1 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Phasin_2 PF09361.5 AJW69991.1 - 0.037 14.0 5.8 1.3 9.1 0.6 2.7 1 1 0 2 2 2 0 Phasin protein Gemini_C4 PF01492.12 AJW69991.1 - 0.048 13.3 0.7 0.1 12.3 0.2 1.8 1 1 0 1 1 1 0 Geminivirus C4 protein Symplekin_C PF12295.3 AJW69991.1 - 0.06 13.2 2.0 0.64 9.9 0.2 2.2 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal NMDAR2_C PF10565.4 AJW69991.1 - 0.11 11.2 1.2 0.12 10.9 0.8 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Img2 PF05046.9 AJW69991.1 - 0.15 12.3 1.1 0.23 11.7 0.7 1.5 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Topoisom_I PF01028.15 AJW69991.1 - 0.52 9.3 7.2 2.7 7.0 5.0 2.1 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core YtzH PF14165.1 AJW69991.1 - 0.71 10.1 4.5 0.28 11.4 0.5 2.1 2 1 0 2 2 2 0 YtzH-like protein V-SNARE_C PF12352.3 AJW69996.1 - 0.048 13.7 1.6 0.048 13.7 1.1 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF4375 PF14300.1 AJW69996.1 - 0.058 13.3 7.2 0.085 12.8 1.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) WXG100 PF06013.7 AJW69996.1 - 0.21 11.6 7.8 0.26 11.2 2.1 2.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF2317 PF10079.4 AJW69996.1 - 0.85 8.1 12.8 1.4 7.3 8.9 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PilJ PF13675.1 AJW69996.1 - 1 9.6 6.8 6.5 7.1 4.1 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3138 PF11336.3 AJW69996.1 - 1.3 7.0 5.1 2.3 6.2 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) FliJ PF02050.11 AJW69996.1 - 1.4 8.9 13.8 2.5 8.1 9.5 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein SNARE PF05739.14 AJW69996.1 - 1.5 8.5 12.0 1.6 8.4 0.1 3.4 3 0 0 3 3 3 0 SNARE domain DUF4509 PF14970.1 AJW69996.1 - 1.8 8.1 10.2 0.89 9.1 4.9 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4509) Stap_Strp_toxin PF01123.15 AJW69996.1 - 2.7 8.5 7.9 2.3 8.7 4.4 1.6 1 1 1 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF1974 PF09317.6 AJW69996.1 - 2.8 7.2 5.8 2.2 7.6 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1974) DUF848 PF05852.6 AJW69996.1 - 2.8 7.7 16.1 1.2 8.9 7.9 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 AJW69996.1 - 3.3 8.0 19.9 1.1 9.5 1.4 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 AJW69996.1 - 3.3 6.5 9.3 4.4 6.1 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.5 AJW69996.1 - 3.7 5.8 12.4 4 5.7 8.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MerR-DNA-bind PF09278.6 AJW69996.1 - 4.3 7.8 8.7 12 6.3 0.4 3.0 3 0 0 3 3 3 0 MerR, DNA binding YPEB PF14620.1 AJW69996.1 - 5.9 5.7 19.5 2.2 7.1 8.0 2.1 1 1 1 2 2 2 0 YpeB sporulation FlgN PF05130.7 AJW69996.1 - 6.5 6.9 18.4 13 6.0 12.6 1.6 1 1 0 1 1 1 0 FlgN protein Med9 PF07544.8 AJW69996.1 - 6.8 6.4 23.4 1.5 8.6 1.8 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LIF_OSM PF01291.12 AJW69996.1 - 7 6.5 9.7 8.7 6.2 0.5 2.8 1 1 1 3 3 3 0 LIF / OSM family DUF1725 PF08333.6 AJW69996.1 - 7.6 6.0 6.4 21 4.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Spectrin PF00435.16 AJW69996.1 - 8.4 6.7 14.3 4.7 7.5 6.0 2.2 1 1 1 2 2 2 0 Spectrin repeat AATF-Che1 PF13339.1 AJW69996.1 - 8.7 6.5 15.3 19 5.4 10.4 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Oxidored-like PF09791.4 AJW69997.1 - 0.19 11.1 1.7 5.3 6.5 0.6 2.7 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal PBP_GOBP PF01395.17 AJW69997.1 - 0.45 10.1 2.9 0.2 11.2 0.2 1.8 2 1 0 2 2 2 0 PBP/GOBP family Tropomyosin_1 PF12718.2 AJW69997.1 - 0.58 9.9 8.7 5.4 6.8 2.3 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF438 PF04282.8 AJW69998.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF438) End3 PF12761.2 AJW69999.1 - 0.048 13.3 2.9 0.048 13.3 2.0 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TMF_TATA_bd PF12325.3 AJW69999.1 - 0.083 12.6 3.1 0.096 12.4 1.8 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.8 AJW69999.1 - 0.1 12.5 1.3 0.17 11.8 0.7 1.6 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF1706 PF08020.6 AJW69999.1 - 0.12 11.9 2.5 0.13 11.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) Cas_Cas6 PF01881.11 AJW69999.1 - 0.48 10.6 2.4 0.55 10.4 1.7 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas6 Prefoldin_2 PF01920.15 AJW69999.1 - 1.5 8.5 7.0 0.23 11.2 1.4 1.9 1 1 1 2 2 2 0 Prefoldin subunit UbiA PF01040.13 AJW70001.1 - 9.1e-23 80.7 21.8 1.2e-22 80.3 15.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Defensin_big PF14862.1 AJW70001.1 - 7.6 6.6 5.6 13 5.9 0.1 2.8 2 1 1 3 3 3 0 Big defensin AsnC_trans_reg PF01037.16 AJW70002.1 - 6.5e-13 48.1 0.1 8.2e-13 47.8 0.1 1.1 1 0 0 1 1 1 1 AsnC family Semialdhyde_dhC PF02774.13 AJW70004.1 - 3.8e-32 111.6 0.0 6.5e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 AJW70004.1 - 2.7e-30 105.1 0.1 9.8e-30 103.3 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 AJW70004.1 - 0.0055 16.1 0.1 1.2 8.6 0.0 3.0 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.15 AJW70004.1 - 0.0069 16.2 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 AJW70004.1 - 0.0071 16.8 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Aminotran_1_2 PF00155.16 AJW70005.1 - 7.6e-52 176.4 0.1 8.5e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CbiA PF01656.18 AJW70006.1 - 2.6e-26 92.2 0.1 3.2e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 AJW70006.1 - 1.4e-18 67.2 0.0 5.2e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AJW70006.1 - 0.00017 21.2 0.0 0.021 14.5 0.0 2.7 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 AJW70006.1 - 0.0025 17.3 0.4 0.33 10.3 0.0 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Miro PF08477.8 AJW70006.1 - 0.0041 17.5 0.0 3.9 7.9 0.0 2.9 3 0 0 3 3 3 1 Miro-like protein AAA_23 PF13476.1 AJW70006.1 - 0.01 16.1 0.1 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AJW70006.1 - 0.01 16.6 0.1 0.11 13.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 AJW70006.1 - 0.027 13.9 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 AJW70006.1 - 0.047 13.2 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AJW70006.1 - 0.054 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 AJW70006.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain VirC1 PF07015.6 AJW70006.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein CobD_Cbib PF03186.8 AJW70007.1 - 1e-97 326.7 0.1 1.2e-97 326.5 0.1 1.0 1 0 0 1 1 1 1 CobD/Cbib protein CobS PF02654.10 AJW70008.1 - 1.1e-52 179.0 20.4 1.2e-52 178.8 14.1 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase NTP_transf_3 PF12804.2 AJW70009.1 - 5e-15 55.9 0.0 5.9e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJW70009.1 - 6.2e-09 35.7 0.0 7.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.18 AJW70009.1 - 5.1e-05 22.6 0.2 9.8e-05 21.7 0.1 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.14 AJW70009.1 - 0.00012 21.8 0.2 0.0019 17.8 0.1 2.0 1 1 0 1 1 1 1 Cytidylyltransferase Ribosomal_L44 PF00935.14 AJW70010.1 - 3.3e-26 91.0 9.1 3.3e-26 91.0 6.3 1.6 1 1 1 2 2 2 1 Ribosomal protein L44 C1_1 PF00130.17 AJW70010.1 - 0.055 13.2 0.8 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rdx PF10262.4 AJW70010.1 - 0.33 11.0 0.3 0.33 11.0 0.2 1.7 2 0 0 2 2 2 0 Rdx family Tnp_zf-ribbon_2 PF13842.1 AJW70010.1 - 5.3 7.5 9.2 10 6.6 2.3 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Adenine_deam_C PF13382.1 AJW70011.1 - 3.7e-49 166.1 0.1 1.4e-48 164.2 0.0 1.9 2 0 0 2 2 2 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.15 AJW70011.1 - 3.6e-19 69.6 0.0 4e-17 62.8 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AJW70011.1 - 1.4e-10 40.8 1.2 4e-10 39.3 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_4 PF13147.1 AJW70011.1 - 6.5e-05 23.0 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 AJW70011.1 - 0.0015 17.8 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Cpn60_TCP1 PF00118.19 AJW70012.1 - 1.2e-164 548.5 16.6 1.5e-164 548.1 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2024 PF09630.5 AJW70013.1 - 1.8e-35 120.5 2.1 1.9e-35 120.3 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Cytochrom_NNT PF03264.9 AJW70013.1 - 0.027 13.9 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region YccJ PF13993.1 AJW70014.1 - 0.037 14.0 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 YccJ-like protein GATase PF00117.23 AJW70015.1 - 3.6e-42 144.0 0.0 5.1e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 AJW70015.1 - 1.1e-31 108.3 0.0 2.6e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 AJW70015.1 - 1.1e-11 44.1 0.4 3.5e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 AJW70015.1 - 8.7e-08 31.8 0.0 3e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 AJW70015.1 - 9.9e-05 21.9 0.0 0.00024 20.7 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.11 AJW70015.1 - 0.00031 19.4 0.1 0.0065 15.0 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 AJW70015.1 - 0.00052 19.5 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 AJW70015.1 - 0.0026 17.0 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 AJW70015.1 - 0.094 12.2 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 PP-loop family IATP PF04568.7 AJW70016.1 - 0.0011 18.9 0.9 0.0022 17.9 0.6 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP MAF_flag10 PF01973.13 AJW70017.1 - 5.1e-41 139.9 0.8 7.8e-41 139.4 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 SBDS PF01172.13 AJW70017.1 - 0.015 15.0 0.3 0.057 13.2 0.0 2.1 2 0 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein TPK_catalytic PF04263.11 AJW70017.1 - 0.039 13.5 0.1 0.11 12.0 0.1 1.7 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain Pterin_bind PF00809.17 AJW70018.1 - 1.8e-37 128.7 0.3 5e-37 127.3 0.2 1.7 1 1 0 1 1 1 1 Pterin binding enzyme DUF1792 PF08759.6 AJW70018.1 - 0.043 13.4 0.4 2.3 7.7 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1792) IMPDH PF00478.20 AJW70019.1 - 7.5e-136 452.6 5.3 8.5e-136 452.4 3.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AJW70019.1 - 2e-23 81.8 0.8 3.6e-11 42.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 AJW70019.1 - 6.7e-10 38.6 9.2 0.00018 20.7 4.6 2.4 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 AJW70019.1 - 6.9e-08 31.7 5.5 4e-07 29.2 3.8 2.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 AJW70019.1 - 7.2e-07 28.7 1.1 0.012 14.9 0.1 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.16 AJW70019.1 - 0.0013 17.7 5.8 0.0043 16.0 0.7 2.4 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase PK PF00224.16 AJW70019.1 - 0.0023 16.5 0.2 0.026 13.1 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain NanE PF04131.9 AJW70019.1 - 0.0028 16.6 1.6 0.0028 16.6 1.1 2.3 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 AJW70019.1 - 0.018 14.0 2.1 0.036 13.1 0.5 2.1 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.1 AJW70019.1 - 0.034 13.3 0.1 0.077 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase B12-binding PF02310.14 AJW70019.1 - 0.034 14.0 0.2 0.079 12.8 0.2 1.6 1 0 0 1 1 1 0 B12 binding domain PcrB PF01884.12 AJW70019.1 - 0.14 11.3 7.3 2.6 7.2 0.3 3.5 2 1 1 4 4 4 0 PcrB family AIM24 PF01987.12 AJW70020.1 - 0.0083 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Beta-APP PF03494.8 AJW70020.1 - 0.049 13.1 0.5 0.12 11.8 0.4 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) PetM PF08041.6 AJW70020.1 - 0.069 12.6 0.1 0.069 12.6 0.1 2.0 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 PDT PF00800.13 AJW70021.1 - 6.9e-59 198.4 0.1 8.8e-59 198.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 AJW70021.1 - 1.4e-06 27.6 0.0 2.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ECR1_N PF14382.1 AJW70022.1 - 7.7e-07 28.2 0.0 3.2e-06 26.3 0.0 2.0 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region Prok-RING_1 PF14446.1 AJW70022.1 - 0.0024 17.5 1.3 0.0054 16.4 0.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 EXOSC1 PF10447.4 AJW70022.1 - 0.0056 16.6 0.6 0.21 11.5 0.2 2.5 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 DUF35_N PF12172.3 AJW70022.1 - 0.13 12.2 1.0 0.3 11.0 0.7 1.6 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DNA_RNApol_7kD PF03604.8 AJW70022.1 - 0.57 9.6 5.6 2.4 7.6 3.9 2.1 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit ADH_zinc_N PF00107.21 AJW70023.1 - 2.9e-29 101.2 0.0 5.9e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AJW70023.1 - 4.4e-26 90.7 0.3 7.2e-26 90.0 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AJW70023.1 - 1.5e-16 61.4 0.0 2.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KTI12 PF08433.5 AJW70023.1 - 0.058 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF773 PF05600.7 AJW70023.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) 6PF2K PF01591.13 AJW70023.1 - 0.15 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TPR_11 PF13414.1 AJW70024.1 - 5e-24 83.7 3.9 1.4e-10 40.6 0.1 3.2 1 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 AJW70024.1 - 3e-22 77.2 1.6 9.2e-08 31.3 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 AJW70024.1 - 3.3e-20 70.3 0.1 0.0001 21.9 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 AJW70024.1 - 2.4e-16 59.9 0.0 1e-05 26.0 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJW70024.1 - 1.2e-13 50.7 0.1 3.4e-05 23.7 0.1 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJW70024.1 - 1.8e-13 50.5 0.0 9.2e-07 29.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AJW70024.1 - 1.6e-11 44.2 9.8 4.1e-05 23.6 0.2 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AJW70024.1 - 8.8e-11 41.4 0.0 0.17 12.5 0.0 5.0 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AJW70024.1 - 2.2e-10 40.2 0.0 0.95 10.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 AJW70024.1 - 2.2e-09 36.4 5.7 0.00032 20.2 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJW70024.1 - 2.5e-07 30.3 6.1 0.04 14.1 0.4 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AJW70024.1 - 3e-07 29.7 0.1 0.026 14.3 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJW70024.1 - 3.7e-07 29.9 0.5 0.17 11.8 0.1 3.7 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 AJW70024.1 - 9.3e-07 28.4 2.2 0.23 11.5 0.0 4.7 5 0 0 5 5 4 2 PPR repeat TPR_10 PF13374.1 AJW70024.1 - 5.9e-05 22.8 0.0 0.94 9.5 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 AJW70024.1 - 0.0004 19.6 0.2 0.71 9.0 0.0 2.1 2 0 0 2 2 2 2 Coatomer epsilon subunit TPR_9 PF13371.1 AJW70024.1 - 0.00048 19.9 0.0 0.25 11.2 0.0 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.2 AJW70024.1 - 0.0016 18.4 0.0 1 9.3 0.0 2.5 2 1 0 2 2 2 1 Tetratrico peptide repeat DDT PF02791.12 AJW70024.1 - 0.016 14.9 0.1 0.61 9.9 0.0 2.9 2 1 1 3 3 3 0 DDT domain RepB PF07506.6 AJW70024.1 - 0.035 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein MIT PF04212.13 AJW70024.1 - 0.057 13.3 1.1 4.9 7.1 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 AJW70024.1 - 0.13 12.4 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Diphthamide_syn PF01866.12 AJW70025.1 - 7.4e-80 268.4 0.0 9.2e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein GSDH PF07995.6 AJW70026.1 - 9.7e-83 277.9 0.0 1.2e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 AJW70026.1 - 0.0017 18.1 0.0 2.3 8.3 0.0 3.6 3 0 0 3 3 3 2 NHL repeat Reg_prop PF07494.6 AJW70026.1 - 0.0033 17.2 2.1 19 5.6 0.0 4.8 4 0 0 4 4 4 1 Two component regulator propeller HMG-CoA_red PF00368.13 AJW70027.1 - 6.9e-82 275.0 6.8 8.5e-82 274.7 4.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HisG PF01634.13 AJW70028.1 - 4e-39 133.8 0.1 5.3e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 AJW70028.1 - 5.4e-14 51.8 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain Histidinol_dh PF00815.15 AJW70029.1 - 1.3e-130 435.7 0.4 1.6e-130 435.4 0.3 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase NBP1 PF08537.5 AJW70029.1 - 0.19 10.9 5.3 0.26 10.4 3.7 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 EIF_2_alpha PF07541.7 AJW70029.1 - 0.21 11.3 1.6 0.31 10.7 0.3 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit UBN_AB PF14075.1 AJW70029.1 - 1.1 8.9 5.5 0.87 9.2 1.6 2.0 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Aminotran_1_2 PF00155.16 AJW70030.1 - 7.7e-43 146.8 0.0 9e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 AJW70030.1 - 2.5e-06 26.4 0.0 3.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.14 AJW70030.1 - 0.061 12.0 0.0 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V DUF2232 PF09991.4 AJW70030.1 - 0.071 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) HAD_2 PF13419.1 AJW70031.1 - 7.6e-07 29.5 0.1 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AJW70031.1 - 3e-05 24.5 0.1 0.00037 20.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 AJW70031.1 - 0.0094 15.3 1.0 0.91 8.8 0.0 2.4 2 0 0 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) GerE PF00196.14 AJW70031.1 - 0.06 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HAD PF12710.2 AJW70031.1 - 0.079 13.1 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase IGPD PF00475.13 AJW70032.1 - 1.9e-49 167.2 0.5 2.6e-49 166.8 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Flagellin_IN PF07196.8 AJW70032.1 - 0.0068 16.3 2.1 0.05 13.5 1.2 2.4 2 0 0 2 2 2 1 Flagellin hook IN motif ANF_receptor PF01094.23 AJW70032.1 - 0.021 13.6 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region GATase PF00117.23 AJW70033.1 - 8.9e-34 116.6 0.0 1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJW70033.1 - 3.1e-05 23.5 0.5 0.00039 19.9 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 AJW70033.1 - 0.00011 21.8 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 AJW70033.1 - 0.0029 17.2 0.0 0.0053 16.3 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain WI12 PF07107.6 AJW70033.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Wound-induced protein WI12 His_biosynth PF00977.16 AJW70034.1 - 1.3e-71 240.4 0.8 1.5e-71 240.3 0.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 AJW70034.1 - 0.0016 17.7 0.8 0.29 10.3 0.1 2.2 2 0 0 2 2 2 2 PcrB family Syd PF07348.7 AJW70034.1 - 0.0071 15.6 0.1 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Syd protein (SUKH-2) IGPS PF00218.16 AJW70034.1 - 0.013 14.5 0.0 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Dus PF01207.12 AJW70034.1 - 0.039 12.7 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 AJW70035.1 - 6.4e-84 280.7 2.4 7.3e-84 280.5 1.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 AJW70035.1 - 8.7e-08 31.3 0.0 0.00053 18.9 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 AJW70035.1 - 1.9e-05 23.8 0.2 0.021 13.9 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI NMO PF03060.10 AJW70035.1 - 4.1e-05 22.8 0.3 0.034 13.2 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase PcrB PF01884.12 AJW70035.1 - 6.7e-05 22.2 0.8 0.00013 21.2 0.1 1.8 2 0 0 2 2 2 1 PcrB family ThiG PF05690.9 AJW70035.1 - 0.00045 19.3 0.3 0.27 10.2 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 AJW70035.1 - 0.0015 17.5 0.1 0.06 12.2 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 AJW70035.1 - 0.011 14.6 1.2 0.13 11.1 0.1 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 AJW70035.1 - 0.03 12.8 0.0 0.048 12.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain PRA-CH PF01502.13 AJW70036.1 - 2.5e-33 113.5 0.0 3e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase DUF4097 PF13349.1 AJW70037.1 - 0.037 13.5 0.2 0.053 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) IncA PF04156.9 AJW70037.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 IncA protein PALP PF00291.20 AJW70038.1 - 1.1e-61 208.7 0.5 1.3e-61 208.5 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme S4 PF01479.20 AJW70038.1 - 0.085 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 S4 domain ThiF PF00899.16 AJW70039.1 - 1.3e-44 151.2 1.3 2.5e-44 150.4 0.9 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AJW70039.1 - 8.7e-17 60.5 0.1 1.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain ThiS PF02597.15 AJW70039.1 - 2.6e-09 37.3 0.0 9.2e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 ThiS family Shikimate_DH PF01488.15 AJW70039.1 - 0.00069 19.7 0.3 0.0024 17.9 0.2 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 AJW70039.1 - 0.12 12.6 0.4 0.36 11.0 0.3 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding He_PIG PF05345.7 AJW70041.1 - 0.034 14.1 3.7 3.5 7.7 0.1 2.9 2 1 0 2 2 2 0 Putative Ig domain Peptidase_S8 PF00082.17 AJW70042.1 - 4.7e-31 107.9 0.2 1.5e-30 106.2 0.1 1.9 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 AJW70042.1 - 5.1e-06 26.8 3.1 0.0006 20.1 0.0 2.7 2 0 0 2 2 2 2 Fn3-like domain (DUF1034) DUF916 PF06030.7 AJW70042.1 - 0.00044 20.0 0.1 2.3 8.0 0.0 3.9 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF916) Rieske PF00355.21 AJW70043.1 - 3e-09 36.3 0.0 4.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_Fe-S_N PF10399.4 AJW70043.1 - 0.0015 17.6 0.1 0.0035 16.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 AJW70043.1 - 0.0018 18.1 0.9 0.0018 18.1 0.6 1.6 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Cytochrom_B_N_2 PF13631.1 AJW70044.1 - 5.4e-25 88.1 6.5 5.4e-25 88.1 4.5 3.7 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 AJW70044.1 - 1.5e-07 31.5 3.1 1.5e-07 31.5 2.2 3.3 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.1 AJW70044.1 - 0.0055 16.8 2.6 0.0055 16.8 1.8 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4405) TRIQK PF15168.1 AJW70044.1 - 1.1 9.2 5.9 0.59 10.0 0.7 3.1 2 1 1 3 3 3 0 Triple QxxK/R motif-containing protein family DUF1418 PF07214.7 AJW70044.1 - 7.1 6.3 7.8 0.8 9.3 1.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) Copper-bind PF00127.15 AJW70045.1 - 9.4e-06 25.7 0.1 1.4e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW70045.1 - 0.0012 18.7 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Cupredoxin-like domain CbiM PF01891.11 AJW70045.1 - 0.11 12.0 0.5 0.16 11.5 0.3 1.2 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region DoxA PF07680.6 AJW70046.1 - 0.03 13.9 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxA DUF4361 PF14274.1 AJW70046.1 - 0.089 12.4 0.4 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) OGG_N PF07934.7 AJW70047.1 - 1e-16 60.9 0.2 3.4e-15 56.0 0.2 2.5 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 AJW70047.1 - 1.2e-14 54.5 0.0 2.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AJW70047.1 - 0.017 14.8 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF512 PF04459.7 AJW70047.1 - 0.061 12.3 0.6 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Beta-Casp PF10996.3 AJW70048.1 - 2.3e-21 76.0 0.0 7.2e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_2 PF12706.2 AJW70048.1 - 2.9e-14 53.0 0.0 5.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AJW70048.1 - 5.4e-14 52.2 0.1 1.7e-13 50.6 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 AJW70048.1 - 3.5e-12 45.9 0.0 1.2e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AJW70048.1 - 1.1e-05 25.2 0.0 3.8e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2220 PF09983.4 AJW70048.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF3000 PF11452.3 AJW70049.1 - 0.08 12.1 0.3 0.078 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Fer4 PF00037.22 AJW70050.1 - 1.7e-11 43.1 10.3 6.6e-06 25.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 AJW70050.1 - 2.1e-10 40.0 7.5 3.6e-05 23.4 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AJW70050.1 - 1.2e-09 38.4 3.8 1.7e-09 37.8 2.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJW70050.1 - 5.7e-09 35.6 3.2 9.5e-09 34.9 2.3 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJW70050.1 - 8e-09 34.9 9.0 0.00011 21.9 1.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 AJW70050.1 - 4.2e-08 32.9 1.4 6.2e-08 32.3 1.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.1 AJW70050.1 - 2.4e-06 27.8 4.9 0.008 16.5 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 AJW70050.1 - 3.1e-06 27.6 8.7 0.00094 19.7 6.2 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_4 PF12800.2 AJW70050.1 - 1.7e-05 24.7 9.7 0.038 14.3 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AJW70050.1 - 3.2e-05 24.0 6.9 0.00015 21.9 5.0 1.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.1 AJW70050.1 - 8.1e-05 23.2 1.5 0.3 11.8 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 AJW70050.1 - 0.00015 21.6 5.0 0.00042 20.2 3.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 AJW70050.1 - 0.0002 21.6 11.3 0.044 14.3 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AJW70050.1 - 0.0023 18.2 6.4 0.05 13.9 4.4 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AJW70050.1 - 0.0037 17.6 6.8 0.19 12.1 1.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain TGT PF01702.13 AJW70051.1 - 3.2e-47 160.8 0.0 4.8e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PA28_alpha PF02251.13 AJW70051.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit AAA_18 PF13238.1 AJW70052.1 - 3.9e-16 59.5 0.6 3.9e-16 59.5 0.4 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AJW70052.1 - 1.2e-13 51.9 0.5 2.4e-13 50.9 0.3 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 AJW70052.1 - 3.6e-07 30.2 0.8 4.3e-06 26.7 0.5 2.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA PF00004.24 AJW70052.1 - 0.0001 22.4 0.2 0.0015 18.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CoaE PF01121.15 AJW70052.1 - 0.00043 19.7 0.6 0.0008 18.8 0.0 1.7 2 0 0 2 2 2 1 Dephospho-CoA kinase NTPase_1 PF03266.10 AJW70052.1 - 0.0012 18.5 3.1 0.0031 17.2 0.1 2.6 2 1 1 3 3 3 1 NTPase AAA_5 PF07728.9 AJW70052.1 - 0.0012 18.5 0.1 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) KTI12 PF08433.5 AJW70052.1 - 0.0015 17.8 0.1 0.0035 16.5 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SKI PF01202.17 AJW70052.1 - 0.0019 18.0 0.6 0.017 14.9 0.0 2.2 2 1 0 2 2 2 1 Shikimate kinase AAA_19 PF13245.1 AJW70052.1 - 0.0038 16.9 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 AJW70052.1 - 0.021 14.4 0.1 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AJW70052.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AJW70052.1 - 0.055 13.4 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AJW70052.1 - 0.069 13.0 0.0 0.087 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 AJW70052.1 - 0.095 11.7 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF2453 PF10507.4 AJW70052.1 - 0.095 12.5 0.2 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) Sigma54_activat PF00158.21 AJW70052.1 - 0.097 12.1 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 AJW70052.1 - 0.1 12.7 0.1 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase MMR_HSR1_C PF08438.5 AJW70053.1 - 4.9e-29 100.7 0.0 1.4e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AJW70053.1 - 2.5e-17 62.9 0.0 2.7e-16 59.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 AJW70053.1 - 6e-10 38.8 0.2 2.3e-09 36.9 0.1 2.1 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 AJW70053.1 - 4.9e-06 25.8 0.2 2.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Peptidase_M22 PF00814.20 AJW70054.1 - 3.9e-73 246.2 0.0 4.6e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF512 PF04459.7 AJW70054.1 - 0.015 14.4 0.0 0.031 13.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF512) CmcH_NodU PF02543.10 AJW70054.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase bPH_3 PF14470.1 AJW70055.1 - 0.045 14.0 1.1 0.4 10.9 0.7 2.0 1 1 0 1 1 1 0 Bacterial PH domain Pkinase PF00069.20 AJW70056.1 - 1.8e-12 47.0 0.2 2.3e-12 46.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 AJW70056.1 - 3.2e-08 33.1 0.2 4.3e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AJW70056.1 - 1.8e-07 30.4 0.0 8.2e-07 28.2 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 AJW70056.1 - 5.3e-06 25.7 0.1 1.2e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AJW70056.1 - 1.4e-05 24.9 0.0 0.0062 16.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 AJW70056.1 - 4e-05 22.9 0.6 5.2e-05 22.5 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Lipoprotein_8 PF02030.10 AJW70056.1 - 0.04 12.4 0.6 0.058 11.8 0.4 1.3 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Ham1p_like PF01725.11 AJW70057.1 - 8.1e-47 159.0 0.1 9.2e-47 158.8 0.1 1.0 1 0 0 1 1 1 1 Ham1 family Wyosine_form PF08608.7 AJW70058.1 - 2e-18 66.2 0.0 1e-17 63.9 0.0 2.2 2 1 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.16 AJW70058.1 - 3.8e-18 66.2 0.0 2e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Paf67 PF10255.4 AJW70058.1 - 0.00092 18.1 0.3 0.0016 17.3 0.2 1.5 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Fer4_14 PF13394.1 AJW70058.1 - 0.0056 16.6 0.2 0.05 13.6 0.1 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain SAS4 PF15460.1 AJW70058.1 - 0.029 14.2 0.7 0.069 13.0 0.1 2.0 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 TSP_3 PF02412.13 AJW70059.1 - 5.7e-44 147.2 260.1 0.00038 19.8 2.3 28.3 27 8 1 28 28 28 20 Thrombospondin type 3 repeat TSP_3 PF02412.13 AJW70060.1 - 8.5e-33 111.5 224.1 0.00029 20.2 1.2 27.2 24 7 6 30 30 30 18 Thrombospondin type 3 repeat TSP_3 PF02412.13 AJW70061.1 - 6.4e-30 102.3 210.2 0.0002 20.7 1.8 25.6 25 8 4 29 29 29 17 Thrombospondin type 3 repeat Dus PF01207.12 AJW70062.1 - 6.6e-76 255.0 0.0 7.8e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 AJW70062.1 - 2.4e-08 33.2 0.1 2.7e-06 26.5 0.1 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.15 AJW70062.1 - 5.1e-06 25.7 0.0 8.5e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NanE PF04131.9 AJW70062.1 - 0.00021 20.3 0.1 0.0015 17.5 0.0 2.2 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 AJW70062.1 - 0.00097 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein IMPDH PF00478.20 AJW70062.1 - 0.0087 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NIR_SIR_ferr PF03460.12 AJW70062.1 - 0.043 13.4 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain PcrB PF01884.12 AJW70062.1 - 0.045 12.9 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 PcrB family FMN_dh PF01070.13 AJW70062.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase AsnC_trans_reg PF01037.16 AJW70063.1 - 3.9e-13 48.8 0.0 4.6e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 AsnC family P-II PF00543.17 AJW70064.1 - 7.9e-11 42.3 2.1 9.4e-11 42.0 1.4 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II HTH_10 PF04967.7 AJW70065.1 - 0.0062 16.0 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 HTH DNA binding domain Ovate PF04844.8 AJW70065.1 - 0.02 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Transcriptional repressor, ovate Mga PF05043.8 AJW70065.1 - 0.059 13.6 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Mga helix-turn-helix domain zf-3CxxC PF13695.1 AJW70066.1 - 0.0077 16.4 0.1 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding domain I-set PF07679.11 AJW70066.1 - 0.032 14.0 0.1 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF2839 PF10999.3 AJW70066.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) CcdA PF07362.7 AJW70066.1 - 0.31 10.9 1.5 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA NERD PF08378.6 AJW70067.1 - 0.004 17.4 0.9 0.036 14.3 0.1 2.1 2 0 0 2 2 2 1 Nuclease-related domain Kinesin PF00225.18 AJW70067.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain TBP PF00352.16 AJW70069.1 - 4.6e-61 202.1 0.1 1.2e-30 104.7 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AJW70069.1 - 1e-05 25.4 0.0 0.0079 16.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ASCH PF04266.9 AJW70070.1 - 1.2e-11 44.8 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 ASCH domain DUF3850 PF12961.2 AJW70070.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3850) PALP PF00291.20 AJW70071.1 - 1.1e-22 80.6 0.2 1.5e-21 76.9 0.0 2.4 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme VWA PF00092.23 AJW70073.1 - 3.8e-07 29.9 0.4 1e-06 28.6 0.0 1.9 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.1 AJW70073.1 - 1.3e-06 28.6 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.9 AJW70074.1 - 2e-23 82.6 0.1 2.9e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AJW70074.1 - 6.2e-13 48.4 0.0 9e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AJW70074.1 - 1.9e-07 31.3 0.0 4.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AJW70074.1 - 2.1e-06 27.6 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 AJW70074.1 - 7.5e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 AJW70074.1 - 0.00023 20.2 0.1 0.0066 15.5 0.0 2.5 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus CbbQ_C PF08406.5 AJW70074.1 - 0.00038 20.4 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA_16 PF13191.1 AJW70074.1 - 0.00056 19.9 0.1 0.00086 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AJW70074.1 - 0.00066 19.8 0.0 0.0016 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 AJW70074.1 - 0.0008 19.8 0.1 0.0029 18.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Sigma54_activ_2 PF14532.1 AJW70074.1 - 0.0011 18.9 0.0 0.0047 16.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 AJW70074.1 - 0.0023 17.7 0.0 0.0043 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJW70074.1 - 0.0026 18.5 0.0 0.0053 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 AJW70074.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 AJW70074.1 - 0.0079 15.9 0.1 0.015 14.9 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase Mg_chelatase PF01078.16 AJW70074.1 - 0.01 14.9 0.1 0.8 8.8 0.0 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AJW70074.1 - 0.013 15.0 0.0 0.074 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 AJW70074.1 - 0.019 14.0 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 KaiC KAP_NTPase PF07693.9 AJW70074.1 - 0.025 13.5 0.0 0.034 13.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain T2SE PF00437.15 AJW70074.1 - 0.032 13.1 0.1 0.098 11.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 AJW70074.1 - 0.034 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 AJW70074.1 - 0.037 13.5 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 AJW70074.1 - 0.038 13.7 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 AJW70074.1 - 0.054 12.4 0.8 1.1 8.2 0.1 2.1 2 0 0 2 2 2 0 Septin DUF258 PF03193.11 AJW70074.1 - 0.061 12.5 0.1 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 AJW70074.1 - 0.064 12.6 0.1 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_35 PF14516.1 AJW70074.1 - 0.066 11.8 0.0 0.095 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 AJW70074.1 - 0.067 13.4 0.4 0.15 12.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AJW70074.1 - 0.077 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AJW70074.1 - 0.092 13.0 0.1 0.25 11.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 AJW70074.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAO PF01266.19 AJW70075.1 - 2.3e-05 23.4 0.0 0.078 11.8 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AJW70075.1 - 9.5e-05 21.4 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 AJW70075.1 - 0.002 17.1 0.0 0.0032 16.4 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 AJW70075.1 - 0.002 17.2 0.0 0.005 15.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AJW70075.1 - 0.0031 16.1 0.1 0.0069 15.0 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 AJW70075.1 - 0.01 14.3 0.1 0.35 9.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GDI PF00996.13 AJW70075.1 - 0.023 13.0 0.0 0.049 11.9 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 AJW70075.1 - 0.029 14.7 0.2 0.85 10.0 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AJW70075.1 - 0.083 11.9 0.2 0.38 9.7 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.13 AJW70075.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 AJW70075.1 - 0.22 11.3 2.9 0.93 9.3 2.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA_binding PF01877.12 AJW70076.1 - 2.6e-26 91.9 7.4 3.2e-26 91.6 5.1 1.1 1 0 0 1 1 1 1 RNA binding HD_3 PF13023.1 AJW70076.1 - 0.0049 16.6 1.1 0.006 16.3 0.8 1.2 1 0 0 1 1 1 1 HD domain IFN-gamma PF00714.12 AJW70076.1 - 2.5 7.9 9.0 0.52 10.1 3.6 1.8 2 1 1 3 3 3 0 Interferon gamma Ribosomal_S3Ae PF01015.13 AJW70077.1 - 9.1e-64 214.3 4.1 1e-63 214.2 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Band_7 PF01145.20 AJW70077.1 - 0.018 14.9 0.3 0.13 12.1 0.2 2.1 1 1 0 1 1 1 0 SPFH domain / Band 7 family DUF1062 PF06353.7 AJW70077.1 - 0.091 12.9 0.3 0.15 12.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1062) DUF4468 PF14730.1 AJW70077.1 - 0.093 12.4 0.2 0.26 10.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold tRNA-synt_2b PF00587.20 AJW70078.1 - 2e-36 125.1 0.1 3.4e-36 124.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AJW70078.1 - 1.2e-27 96.0 9.9 2.4e-27 95.0 6.8 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pcc1 PF09341.5 AJW70079.1 - 0.00093 19.1 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 DHHA1 PF02272.14 AJW70080.1 - 2.2e-10 40.0 0.4 1.9e-09 37.0 0.1 2.6 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.15 AJW70080.1 - 4e-08 33.0 0.1 7.1e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 DHH family Ribosomal_S13_N PF08069.7 AJW70081.1 - 6.7e-27 93.1 0.4 1.2e-26 92.2 0.3 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AJW70081.1 - 4.1e-19 68.1 0.4 7.7e-19 67.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DUF1469 PF07332.6 AJW70082.1 - 0.74 9.5 3.9 0.37 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) PRY PF13765.1 AJW70083.1 - 0.089 12.3 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 SPRY-associated domain FixQ PF05545.6 AJW70084.1 - 9.3 5.9 9.0 26 4.5 6.2 1.9 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Monooxygenase_B PF04744.7 AJW70087.1 - 1.5e-06 27.2 0.1 3.5e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Monooxygenase subunit B protein AmoC PF04896.7 AJW70088.1 - 2.3e-15 56.3 4.5 2.9e-15 55.9 3.1 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C TctB PF07331.6 AJW70089.1 - 0.35 10.5 5.3 0.49 10.0 3.7 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Archaeal_AmoA PF12942.2 AJW70090.1 - 2e-105 350.3 9.8 2.4e-105 350.1 6.8 1.0 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) MethyltransfD12 PF02086.10 AJW70091.1 - 8.2e-65 218.8 1.1 9.4e-65 218.6 0.8 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 AJW70091.1 - 0.0002 21.3 0.0 0.00036 20.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF2089 PF09862.4 AJW70091.1 - 0.0024 17.6 0.1 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) DNA_photolyase PF00875.13 AJW70091.1 - 0.011 15.4 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 DNA photolyase Cons_hypoth95 PF03602.10 AJW70091.1 - 0.017 14.4 0.0 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Minor_capsid_1 PF10665.4 AJW70091.1 - 0.042 13.6 0.1 9.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Minor capsid protein zf-Mss51 PF13824.1 AJW70092.1 - 0.025 14.4 0.1 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 LOH1CR12 PF10158.4 AJW70092.1 - 0.036 13.8 0.1 0.14 11.9 0.2 1.8 1 1 1 2 2 2 0 Tumour suppressor protein TcdA_TcdB PF12919.2 AJW70092.1 - 0.095 11.1 0.5 0.11 10.9 0.3 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF217 PF02697.9 AJW70092.1 - 0.26 11.5 1.7 2.3 8.5 0.5 2.5 2 1 0 2 2 2 0 Uncharacterized ACR, COG1753 Response_reg PF00072.19 AJW70093.1 - 8.5e-13 48.3 0.2 9.9e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_18 PF12847.2 AJW70093.1 - 0.019 15.5 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HTH_23 PF13384.1 AJW70094.1 - 4e-05 23.1 0.0 9.1e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain B12-binding_2 PF02607.12 AJW70094.1 - 0.00037 20.4 0.0 0.00071 19.5 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain HTH_24 PF13412.1 AJW70094.1 - 0.00057 19.2 0.4 0.0012 18.1 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 AJW70094.1 - 0.036 14.0 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3203 PF11462.3 AJW70094.1 - 0.042 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) HTH_36 PF13730.1 AJW70094.1 - 0.052 13.6 0.2 7 6.8 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_IclR PF09339.5 AJW70094.1 - 0.059 12.9 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_11 PF08279.7 AJW70094.1 - 0.086 12.4 0.9 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 HTH domain DUF3852 PF12963.2 AJW70094.1 - 0.096 12.7 0.0 0.76 9.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) AhpC-TSA PF00578.16 AJW70095.1 - 1.4e-22 79.6 0.1 1.9e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJW70095.1 - 4.7e-14 52.1 0.0 6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 AJW70095.1 - 8e-09 35.5 0.1 1.5e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AJW70095.1 - 8.6e-07 29.1 0.1 1.2e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 AJW70095.1 - 0.018 14.8 0.3 0.43 10.4 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin domain Thioredoxin PF00085.15 AJW70095.1 - 0.021 14.4 0.1 1.4 8.6 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin T4_deiodinase PF00837.12 AJW70095.1 - 0.045 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase BAR_2 PF10455.4 AJW70095.1 - 0.086 11.7 0.2 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Zn_dep_PLPC PF00882.13 AJW70095.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C UPF0180 PF03698.8 AJW70096.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) A2M_N PF01835.14 AJW70097.1 - 6.8e-06 26.2 0.1 9.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 MG2 domain CTP_transf_2 PF01467.21 AJW70098.1 - 2.1e-14 53.8 0.0 3.9e-13 49.7 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 AJW70098.1 - 0.036 13.7 0.2 0.053 13.1 0.2 1.7 1 1 0 1 1 1 0 FAD synthetase DUF3997 PF13162.1 AJW70099.1 - 0.065 13.0 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Lar_restr_allev PF14354.1 AJW70100.1 - 0.02 15.1 5.3 21 5.4 0.0 3.8 1 1 2 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.2 AJW70100.1 - 0.022 14.5 9.9 0.28 11.0 2.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 AJW70100.1 - 0.35 11.0 3.2 1.6 8.9 0.3 2.8 3 0 0 3 3 3 0 CHY zinc finger zf-UBR PF02207.15 AJW70100.1 - 0.8 9.4 5.8 0.46 10.2 0.7 2.6 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zinc_ribbon_6 PF14599.1 AJW70100.1 - 0.88 9.4 11.1 0.78 9.5 3.3 3.3 3 1 1 4 4 4 0 Zinc-ribbon zf-ribbon_3 PF13248.1 AJW70100.1 - 1.4 8.2 16.3 2.4 7.4 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Molybdop_Fe4S4 PF04879.11 AJW70100.1 - 1.7 8.5 6.8 0.53 10.1 1.5 2.3 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain LIM PF00412.17 AJW70100.1 - 4.3 7.4 7.6 0.52 10.4 1.3 2.3 3 0 0 3 3 3 0 LIM domain OrfB_Zn_ribbon PF07282.6 AJW70100.1 - 4.9 6.8 11.7 11 5.7 0.0 3.3 3 1 2 5 5 5 0 Putative transposase DNA-binding domain Polysacc_deac_1 PF01522.16 AJW70101.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide deacetylase tRNA-synt_1b PF00579.20 AJW70102.1 - 1.3e-30 106.5 0.0 2.2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 AJW70102.1 - 0.0079 14.9 0.0 0.053 12.1 0.0 2.1 1 1 1 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_2d PF01409.15 AJW70103.1 - 1.1e-85 286.7 0.1 1.4e-85 286.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 AJW70103.1 - 0.00015 21.3 0.1 0.00045 19.8 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 AJW70103.1 - 0.00023 20.0 0.3 0.0051 15.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) B5 PF03484.10 AJW70104.1 - 5.4e-22 77.4 0.0 1.6e-16 59.8 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.12 AJW70104.1 - 1.6e-11 43.9 0.3 3.1e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 B3/4 domain tRNA-synt_2d PF01409.15 AJW70104.1 - 0.027 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Neurensin PF14927.1 AJW70105.1 - 2e-05 23.9 0.2 2.3e-05 23.7 0.1 1.0 1 0 0 1 1 1 1 Neurensin DUF308 PF03729.8 AJW70105.1 - 0.0044 16.9 6.4 0.5 10.3 0.9 2.1 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) O-antigen_lig PF13425.1 AJW70105.1 - 0.012 15.5 2.2 0.019 14.9 1.5 1.3 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF3784 PF12650.2 AJW70105.1 - 0.017 15.0 2.5 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF4405 PF14358.1 AJW70105.1 - 0.073 13.2 3.2 3.9 7.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DUF4418 PF14387.1 AJW70105.1 - 0.078 12.7 1.1 0.76 9.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) SdpI PF13630.1 AJW70105.1 - 0.29 10.8 3.5 1.9 8.2 0.6 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family ABC2_membrane PF01061.19 AJW70105.1 - 0.3 10.1 3.6 0.48 9.5 2.5 1.3 1 1 0 1 1 1 0 ABC-2 type transporter Oxidored_q3 PF00499.15 AJW70105.1 - 0.36 10.6 5.1 0.41 10.4 3.5 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 7TM_GPCR_Srh PF10318.4 AJW70105.1 - 0.36 9.5 5.6 0.32 9.7 0.4 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh MMgT PF10270.4 AJW70105.1 - 0.49 10.8 4.9 1.8 9.0 0.2 2.1 1 1 1 2 2 2 0 Membrane magnesium transporter DUF3185 PF11381.3 AJW70105.1 - 1.9 8.3 11.2 0.41 10.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3953 PF13129.1 AJW70105.1 - 2 8.1 13.6 0.49 10.0 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DUF1700 PF08006.6 AJW70105.1 - 6.3 6.0 7.3 1.7 7.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) PGPGW PF09656.5 AJW70105.1 - 6.5 6.1 11.1 0.57 9.5 1.3 2.1 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) DUF3955 PF13127.1 AJW70105.1 - 9.2 5.8 9.4 12 5.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) DUF4064 PF13273.1 AJW70105.1 - 9.6 6.3 11.5 24 5.0 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) EVE PF01878.13 AJW70107.1 - 1.6e-39 135.2 0.5 1.8e-39 135.0 0.3 1.0 1 0 0 1 1 1 1 EVE domain AsnC_trans_reg PF01037.16 AJW70108.1 - 1.7e-11 43.6 0.0 2e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 AsnC family Aconitase PF00330.15 AJW70111.1 - 5.6e-150 499.8 0.1 7.1e-149 496.2 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AJW70111.1 - 7.3e-37 126.4 0.1 3.2e-36 124.3 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.8 AJW70111.1 - 0.014 14.0 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DUF1890 PF09001.6 AJW70112.1 - 0.038 13.9 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) DUF4367 PF14285.1 AJW70112.1 - 0.99 8.6 5.6 1.2 8.4 3.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4367) SOR_SNZ PF01680.12 AJW70113.1 - 2.4e-88 295.1 3.4 2.4e-88 295.1 2.4 1.3 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 AJW70113.1 - 3.8e-08 32.7 1.5 7.8e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 AJW70113.1 - 0.00035 19.9 1.7 0.07 12.3 0.1 3.2 2 1 0 2 2 2 1 Histidine biosynthesis protein OMPdecase PF00215.19 AJW70113.1 - 0.00048 19.5 0.3 0.15 11.4 0.0 2.6 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Dus PF01207.12 AJW70113.1 - 0.00061 18.7 0.3 0.36 9.5 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 AJW70113.1 - 0.00064 18.8 0.0 0.0072 15.4 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 AJW70113.1 - 0.0013 18.0 6.2 0.079 12.0 0.2 2.5 2 1 1 3 3 3 2 Nitronate monooxygenase NanE PF04131.9 AJW70113.1 - 0.092 11.7 3.4 0.59 9.0 0.0 3.0 2 2 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase SNO PF01174.14 AJW70114.1 - 5.4e-49 166.3 0.0 6.2e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase PF00117.23 AJW70114.1 - 1.3e-13 50.8 0.0 2.4e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 AJW70114.1 - 1.7e-13 50.4 0.1 5.2e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 AJW70114.1 - 1.7e-06 27.8 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.8 AJW70114.1 - 2.4e-06 27.1 0.0 2.9e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 AJW70114.1 - 0.00075 18.9 0.0 0.0046 16.4 0.0 2.0 1 1 1 2 2 2 1 DJ-1/PfpI family OmpH PF03938.9 AJW70115.1 - 0.0004 20.3 7.0 0.0004 20.3 4.9 2.5 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.7 AJW70115.1 - 0.09 12.6 4.4 0.093 12.5 0.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC2_membrane_3 PF12698.2 AJW70115.1 - 0.22 10.5 4.5 0.68 8.9 3.1 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Peptidase_S10 PF00450.17 AJW70115.1 - 4.6 6.2 9.3 6.8 5.7 6.5 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase Apolipoprotein PF01442.13 AJW70115.1 - 5 6.5 50.3 45 3.4 34.9 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain tRNA-synt_1 PF00133.17 AJW70117.1 - 1.9e-109 366.3 0.1 1.2e-108 363.6 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AJW70117.1 - 4.8e-31 107.5 2.1 4.8e-31 107.5 1.5 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AJW70117.1 - 3.5e-25 88.4 0.6 2.8e-13 49.2 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AJW70117.1 - 0.00018 20.8 0.0 0.1 11.8 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 PTPS PF01242.14 AJW70118.1 - 7e-20 70.9 0.1 1.9e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase Pterin_4a PF01329.14 AJW70119.1 - 6.5e-33 112.3 0.3 7e-33 112.2 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 AJW70119.1 - 0.013 15.3 0.1 0.025 14.4 0.0 1.6 1 1 1 2 2 2 0 Translation-initiation factor 2 Asn_synthase PF00733.16 AJW70120.1 - 1.9e-31 109.5 0.0 3.7e-31 108.5 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AJW70120.1 - 3.1e-07 29.5 0.2 1.5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 AJW70120.1 - 0.00058 19.2 0.0 0.0011 18.2 0.0 1.7 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF2683 PF10884.3 AJW70120.1 - 0.011 15.5 0.4 0.011 15.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) ATP_bind_3 PF01171.15 AJW70120.1 - 0.019 14.4 0.1 0.12 11.9 0.0 2.2 2 1 0 2 2 2 0 PP-loop family Lyase_1 PF00206.15 AJW70121.1 - 2.1e-48 165.1 1.6 3.1e-48 164.5 1.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 AJW70121.1 - 2.8e-19 68.8 0.0 6.6e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus UPF0542 PF15086.1 AJW70122.1 - 0.055 13.1 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CBS PF00571.23 AJW70123.1 - 3.8e-26 90.5 4.6 1.1e-13 50.6 0.1 2.1 2 0 0 2 2 2 2 CBS domain Apo-CII PF05355.6 AJW70123.1 - 0.14 12.0 0.4 0.46 10.3 0.1 2.0 2 0 0 2 2 2 0 Apolipoprotein C-II Usp PF00582.21 AJW70124.1 - 3.3e-31 108.3 0.0 3.7e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Cactin_mid PF10312.4 AJW70125.1 - 0.11 11.7 0.4 0.11 11.7 0.3 1.0 1 0 0 1 1 1 0 Conserved mid region of cactin MBF1 PF08523.5 AJW70126.1 - 0.022 14.7 9.0 0.027 14.5 6.2 1.3 1 0 0 1 1 1 0 Multiprotein bridging factor 1 DUF3972 PF13118.1 AJW70126.1 - 0.23 11.5 3.6 0.26 11.3 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Borrelia_P83 PF05262.6 AJW70126.1 - 0.51 8.5 12.5 0.53 8.4 8.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Lumazine_bd PF12870.2 AJW70126.1 - 0.64 10.0 6.4 0.79 9.7 4.4 1.0 1 0 0 1 1 1 0 Lumazine-binding domain Atg14 PF10186.4 AJW70126.1 - 4.9 6.0 7.4 5 5.9 5.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RtcB PF01139.12 AJW70127.1 - 4.2e-151 503.6 0.0 4.7e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Complex1_LYR PF05347.10 AJW70127.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF3492 PF11997.3 AJW70127.1 - 0.096 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) dsDNA_bind PF01984.15 AJW70128.1 - 8.6e-06 25.6 0.7 1.1e-05 25.3 0.5 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.4 AJW70128.1 - 0.0036 17.4 2.6 0.0036 17.4 1.8 1.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Spc24 PF08286.6 AJW70128.1 - 0.024 14.3 2.3 0.32 10.6 0.6 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 EcoEI_R_C PF08463.5 AJW70129.1 - 0.013 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal Ribosomal_S11 PF00411.14 AJW70130.1 - 2e-38 130.9 0.8 2.7e-38 130.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 AIRS PF00586.19 AJW70132.1 - 1.4e-11 44.4 0.0 2.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.17 AJW70132.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain TusA PF01206.12 AJW70132.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Sulfurtransferase TusA PGM_PMM_I PF02878.11 AJW70133.1 - 5.9e-24 84.1 0.0 1.6e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AJW70133.1 - 3.8e-14 52.6 0.0 7.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AJW70133.1 - 3.5e-12 46.5 0.0 7.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AJW70133.1 - 1.3e-08 34.7 0.1 4e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain B12-binding PF02310.14 AJW70133.1 - 0.017 15.0 0.0 0.35 10.7 0.0 2.4 1 1 0 1 1 1 0 B12 binding domain AgrB PF04647.10 AJW70137.1 - 0.071 12.1 0.6 0.093 11.7 0.4 1.2 1 0 0 1 1 1 0 Accessory gene regulator B DUF1129 PF06570.6 AJW70137.1 - 0.072 12.3 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) UPF0104 PF03706.8 AJW70137.1 - 0.084 12.1 0.0 0.084 12.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) ABC2_membrane_5 PF13346.1 AJW70137.1 - 0.1 11.8 4.2 0.41 9.9 3.5 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein O-antigen_lig PF13425.1 AJW70137.1 - 0.12 12.4 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4083 PF13314.1 AJW70137.1 - 0.24 11.2 1.7 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF2500 PF10694.4 AJW70137.1 - 0.51 10.3 2.4 0.81 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Ycf9 PF01737.12 AJW70137.1 - 1.4 8.3 4.2 2.4 7.6 3.0 1.6 1 1 0 1 1 1 0 YCF9 HTH_45 PF14947.1 AJW70138.1 - 3.2e-17 62.0 0.2 5.3e-17 61.4 0.1 1.4 2 0 0 2 2 2 1 Winged helix-turn-helix Mrr_N PF14338.1 AJW70138.1 - 0.00021 21.3 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 Mrr N-terminal domain HTH_34 PF13601.1 AJW70138.1 - 0.00039 20.3 0.1 0.00053 19.9 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Ribosomal_S19e PF01090.14 AJW70138.1 - 0.0011 18.3 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19e RNA_pol_Rpc34 PF05158.7 AJW70138.1 - 0.0013 18.0 0.1 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 AJW70138.1 - 0.0015 18.5 0.1 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator RPA_C PF08784.6 AJW70138.1 - 0.01 16.2 0.1 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 Replication protein A C terminal TrmB PF01978.14 AJW70138.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 AJW70138.1 - 0.027 14.2 0.1 0.071 12.8 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF4364 PF14277.1 AJW70138.1 - 0.031 13.8 0.1 0.052 13.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) NIT PF08376.5 AJW70138.1 - 0.096 12.1 0.1 1 8.8 0.1 1.9 2 0 0 2 2 2 0 Nitrate and nitrite sensing MarR PF01047.17 AJW70138.1 - 0.13 12.0 0.2 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 MarR family DUF4475 PF14753.1 AJW70139.1 - 0.0077 15.7 1.7 0.012 15.1 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) DUF4428 PF14471.1 AJW70140.1 - 0.0022 17.7 4.4 0.0076 15.9 3.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4428) Thg1C PF14413.1 AJW70140.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Thg1 C terminal domain DiS_P_DiS PF06750.8 AJW70140.1 - 0.27 11.0 1.7 0.39 10.5 0.4 1.6 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain AIPR PF10592.4 AJW70141.1 - 4.8e-65 219.8 8.4 4.8e-65 219.8 5.8 2.8 3 0 0 3 3 3 2 AIPR protein Copper-bind PF00127.15 AJW70142.1 - 6.3e-09 35.9 0.6 2.9e-08 33.8 0.1 2.1 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW70142.1 - 1.9e-07 30.9 0.0 8.2e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Cupredoxin-like domain ODV-E18 PF10717.4 AJW70142.1 - 0.097 12.1 1.1 0.19 11.1 0.8 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CBFD_NFYB_HMF PF00808.18 AJW70143.1 - 1.2e-13 50.8 0.2 1.3e-13 50.7 0.1 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AJW70143.1 - 2.8e-07 30.5 0.1 3.5e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AJW70143.1 - 2.7e-05 24.2 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 AJW70143.1 - 0.0027 17.4 0.0 0.0031 17.3 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 AJW70143.1 - 0.0041 16.8 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 AJW70143.1 - 0.0095 16.2 0.1 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAF PF02969.12 AJW70143.1 - 0.071 13.0 0.6 0.077 12.9 0.4 1.1 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TatD_DNase PF01026.16 AJW70144.1 - 1.6e-43 148.7 0.0 1.8e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Ribosomal_S17e PF00833.13 AJW70145.1 - 1.9e-20 72.8 4.8 1.9e-20 72.8 3.3 1.4 1 1 0 1 1 1 1 Ribosomal S17 Otopetrin PF03189.8 AJW70145.1 - 0.014 14.4 0.6 0.016 14.2 0.4 1.1 1 0 0 1 1 1 0 Otopetrin CBFD_NFYB_HMF PF00808.18 AJW70145.1 - 0.031 14.3 2.3 5.8 7.0 0.2 2.9 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CGI-121 PF08617.5 AJW70146.1 - 3.1e-08 33.4 6.1 4.1e-08 33.0 3.8 1.5 1 1 0 1 1 1 1 Kinase binding protein CGI-121 ThiS PF02597.15 AJW70146.1 - 1.2e-07 32.0 0.0 4.4e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 ThiS family Urm1 PF09138.6 AJW70146.1 - 0.0035 17.4 3.1 0.0053 16.8 0.7 2.5 2 1 0 2 2 2 1 Urm1 (Ubiquitin related modifier) THUMP PF02926.12 AJW70147.1 - 2.5e-13 50.1 3.3 2.9e-13 49.9 2.3 1.2 1 0 0 1 1 1 1 THUMP domain Ribosomal_S19e PF01090.14 AJW70147.1 - 0.19 11.1 0.9 2.7 7.4 0.0 2.6 1 1 2 3 3 3 0 Ribosomal protein S19e HSBP1 PF06825.7 AJW70147.1 - 0.64 9.6 3.6 0.77 9.3 0.2 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Sua5_yciO_yrdC PF01300.13 AJW70148.1 - 9e-50 168.3 0.0 1e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination YfhD PF14151.1 AJW70149.1 - 3.5 7.8 6.4 3.2 7.9 4.5 1.1 1 0 0 1 1 1 0 YfhD-like protein HTH_45 PF14947.1 AJW70150.1 - 3e-13 49.3 0.1 4e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 AJW70150.1 - 7.6e-08 31.9 0.0 1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AJW70150.1 - 3.6e-06 27.2 0.2 4.5e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.5 AJW70150.1 - 3.9e-05 23.1 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.14 AJW70150.1 - 4.2e-05 23.1 0.0 5.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 AJW70150.1 - 0.00012 21.3 0.1 0.0002 20.6 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.1 AJW70150.1 - 0.00053 19.9 0.0 0.00082 19.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.17 AJW70150.1 - 0.00075 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 MarR family Mrr_N PF14338.1 AJW70150.1 - 0.0014 18.6 0.0 0.002 18.2 0.0 1.3 1 1 0 1 1 1 1 Mrr N-terminal domain HTH_20 PF12840.2 AJW70150.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain RQC PF09382.5 AJW70150.1 - 0.0025 17.4 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 RQC domain RPA_C PF08784.6 AJW70150.1 - 0.0037 17.6 0.0 0.0057 17.0 0.0 1.3 1 1 0 1 1 1 1 Replication protein A C terminal DUF4194 PF13835.1 AJW70150.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Rrf2 PF02082.15 AJW70150.1 - 0.013 15.6 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR PF03551.9 AJW70150.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_Crp_2 PF13545.1 AJW70150.1 - 0.029 14.1 0.5 0.089 12.5 0.2 1.7 1 1 0 2 2 2 0 Crp-like helix-turn-helix domain DUF4364 PF14277.1 AJW70150.1 - 0.029 13.9 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) RNA_pol_Rpc34 PF05158.7 AJW70150.1 - 0.03 13.5 0.0 0.03 13.5 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_5 PF01022.15 AJW70150.1 - 0.043 13.4 0.1 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RP-C PF03428.8 AJW70150.1 - 0.057 12.8 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF2250 PF10007.4 AJW70150.1 - 0.065 13.1 0.1 0.16 11.9 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) FUR PF01475.14 AJW70150.1 - 0.1 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family Rio2_N PF09202.6 AJW70150.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Rio2, N-terminal HxlR PF01638.12 AJW70150.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PIRT PF15099.1 AJW70151.1 - 0.0073 15.5 0.6 0.0073 15.5 0.4 2.3 1 1 1 2 2 2 1 Phosphoinositide-interacting protein family zinc-ribbons_6 PF07191.7 AJW70152.1 - 0.02 14.6 0.5 0.026 14.2 0.4 1.2 1 0 0 1 1 1 0 zinc-ribbons Zn_Tnp_IS1 PF03811.8 AJW70152.1 - 0.032 13.7 0.5 0.9 9.0 0.1 2.3 2 0 0 2 2 2 0 InsA N-terminal domain zinc_ribbon_4 PF13717.1 AJW70152.1 - 0.043 13.4 6.0 0.76 9.5 4.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJW70152.1 - 0.047 13.2 6.1 0.73 9.4 4.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 AJW70152.1 - 0.057 13.2 0.7 0.078 12.7 0.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-TFIIB PF13453.1 AJW70152.1 - 0.075 12.2 1.0 0.25 10.5 0.8 1.8 2 1 0 2 2 2 0 Transcription factor zinc-finger RIG-I_C-RD PF11648.3 AJW70152.1 - 0.12 12.2 1.1 8.9 6.2 0.0 2.0 1 1 1 2 2 2 0 C-terminal domain of RIG-I Mu-like_Com PF10122.4 AJW70152.1 - 0.2 10.7 4.3 0.88 8.6 0.5 2.2 1 1 0 2 2 2 0 Mu-like prophage protein Com DUF329 PF03884.9 AJW70152.1 - 0.45 10.1 2.4 1.1 8.8 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF329) Ribosomal_S27e PF01667.12 AJW70152.1 - 0.45 10.1 5.3 3.8 7.1 3.7 2.1 1 1 0 1 1 1 0 Ribosomal protein S27 Lar_restr_allev PF14354.1 AJW70152.1 - 0.47 10.8 2.2 1.9 8.8 1.5 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 AJW70152.1 - 0.94 8.7 4.0 3.4 7.0 2.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-HIT PF04438.11 AJW70152.1 - 0.94 9.1 4.8 3.7 7.2 0.2 2.7 3 0 0 3 3 3 0 HIT zinc finger Iron_traffic PF04362.9 AJW70153.1 - 2.8e-08 33.0 2.5 3.6e-08 32.7 1.7 1.4 1 1 0 1 1 1 1 Bacterial Fe(2+) trafficking zinc_ribbon_2 PF13240.1 AJW70153.1 - 0.02 14.3 1.7 0.051 13.0 1.2 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Syd PF07348.7 AJW70153.1 - 0.086 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Syd protein (SUKH-2) Fcf2 PF08698.6 AJW70153.1 - 0.23 11.4 1.6 0.49 10.4 0.9 1.7 1 1 1 2 2 2 0 Fcf2 pre-rRNA processing Annexin PF00191.15 AJW70154.1 - 0.0044 16.8 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Annexin Adenylsucc_synt PF00709.16 AJW70155.1 - 8.1e-88 294.8 1.8 2e-42 145.3 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase OMPdecase PF00215.19 AJW70157.1 - 2.8e-27 95.5 0.0 3.5e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NUDIX PF00293.23 AJW70158.1 - 4e-17 62.1 0.0 5.1e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.1 AJW70158.1 - 0.0039 16.6 0.1 0.0051 16.3 0.1 1.2 1 0 0 1 1 1 1 DBC1 DUF2661 PF10860.3 AJW70158.1 - 0.054 13.6 0.9 0.085 13.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) Prenyltransf PF01255.14 AJW70159.1 - 4.3e-78 261.4 0.1 5.9e-78 261.0 0.1 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF373 PF04123.8 AJW70160.1 - 2.9e-107 358.6 9.6 3.3e-107 358.4 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF4229 PF14012.1 AJW70160.1 - 7.8 6.4 11.1 39 4.2 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) UPF0118 PF01594.11 AJW70161.1 - 0.021 13.8 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 Imm35 PF15581.1 AJW70161.1 - 0.059 13.3 0.7 0.12 12.4 0.2 1.7 2 0 0 2 2 2 0 Immunity protein 35 HypA PF01155.14 AJW70163.1 - 0.023 14.3 0.4 0.027 14.1 0.3 1.0 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Antiterm PF03589.8 AJW70163.1 - 0.029 14.4 0.5 0.033 14.2 0.3 1.1 1 0 0 1 1 1 0 Antitermination protein DZR PF12773.2 AJW70163.1 - 0.035 13.9 2.9 0.069 12.9 2.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon GFA PF04828.9 AJW70163.1 - 0.037 13.9 2.4 0.061 13.2 0.0 1.8 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 AJW70163.1 - 0.066 12.4 1.3 0.41 9.9 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF3795 PF12675.2 AJW70163.1 - 0.077 13.1 0.4 0.085 13.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) Auto_anti-p27 PF06677.7 AJW70163.1 - 0.11 12.3 1.5 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.1 AJW70163.1 - 0.13 11.7 1.3 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2072 PF09845.4 AJW70163.1 - 0.23 11.3 1.0 0.33 10.8 0.7 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-ISL3 PF14690.1 AJW70163.1 - 0.34 10.9 3.1 5.6 7.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC4_3 PF13920.1 AJW70163.1 - 0.4 10.3 3.1 2 8.1 2.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 AJW70163.1 - 0.82 9.6 2.9 4.5 7.3 2.0 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 AJW70163.1 - 0.86 9.3 6.5 4 7.2 4.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJW70163.1 - 1 9.0 6.7 4.8 6.8 4.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.12 AJW70164.1 - 1.3e-26 92.7 0.0 1.5e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 AJW70164.1 - 0.0047 16.2 0.6 0.0078 15.5 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2387 PF09526.5 AJW70164.1 - 0.023 14.6 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 AJW70164.1 - 0.027 14.1 0.3 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 AJW70164.1 - 0.05 13.9 0.3 0.078 13.2 0.2 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 AJW70164.1 - 0.18 11.8 1.8 3.2 7.8 0.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-TFIIB PF13453.1 AJW70164.1 - 0.53 9.5 2.6 0.62 9.2 0.8 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF424 PF04242.8 AJW70165.1 - 2.7e-23 81.8 0.3 3.1e-23 81.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) RIO1 PF01163.17 AJW70166.1 - 7.5e-54 181.9 0.0 9.8e-54 181.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 AJW70166.1 - 0.001 18.8 0.0 0.79 9.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AJW70166.1 - 0.0021 17.1 0.0 0.073 12.1 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family KH_1 PF00013.24 AJW70167.1 - 4.9e-15 54.9 8.3 2.3e-07 30.3 0.6 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 AJW70167.1 - 5.9e-06 25.8 8.4 0.016 14.8 1.4 3.0 2 1 1 3 3 3 2 KH domain KH_2 PF07650.12 AJW70167.1 - 0.027 14.0 5.5 1.4 8.4 0.6 2.5 2 0 0 2 2 2 0 KH domain Topo-VIb_trans PF09239.6 AJW70168.1 - 2.2e-57 193.0 0.0 4e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.21 AJW70168.1 - 3.3e-09 36.4 0.0 7.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AJW70168.1 - 6e-08 32.4 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GldM_C PF12080.3 AJW70168.1 - 0.02 14.8 1.3 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 GldM C-terminal domain TP6A_N PF04406.9 AJW70169.1 - 2.8e-19 68.5 0.1 5e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.17 AJW70169.1 - 0.031 14.2 0.4 0.072 13.0 0.0 1.8 2 0 0 2 2 2 0 Toprim domain DUF3169 PF11368.3 AJW70170.1 - 0.0082 15.3 3.1 0.011 15.0 1.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3169) GvpH PF05455.6 AJW70170.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 GvpH RseC_MucC PF04246.7 AJW70170.1 - 0.12 11.9 0.3 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC EII-Sor PF03609.9 AJW70171.1 - 0.053 12.7 3.6 0.094 11.9 2.6 1.4 1 1 0 1 1 1 0 PTS system sorbose-specific iic component DUF3754 PF12576.3 AJW70171.1 - 0.29 10.7 1.4 0.34 10.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) TrmB PF01978.14 AJW70172.1 - 2.6e-05 23.8 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB zf-met PF12874.2 AJW70173.1 - 0.059 13.5 0.4 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF2175 PF09943.4 AJW70173.1 - 3.3 7.8 5.9 14 5.8 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Lant_dehyd_C PF04738.8 AJW70174.1 - 0.054 11.7 0.1 0.13 10.4 0.0 1.5 1 1 1 2 2 2 0 Lantibiotic dehydratase, C terminus PNP_UDP_1 PF01048.15 AJW70175.1 - 2.2e-46 157.7 0.0 2.5e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pribosyltran PF00156.22 AJW70176.1 - 1.1e-18 67.1 0.2 1.3e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AJW70176.1 - 0.0024 17.1 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase A2M_N PF01835.14 AJW70177.1 - 2.2e-26 91.9 0.4 9.2e-07 29.0 0.0 6.1 7 0 0 7 7 7 5 MG2 domain FlgD_ig PF13860.1 AJW70177.1 - 2e-06 27.4 2.5 0.11 12.2 0.0 6.1 6 1 1 7 7 7 1 FlgD Ig-like domain DUF1973 PF09315.6 AJW70177.1 - 0.0015 18.0 0.0 0.016 14.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1973) DUF4384 PF14326.1 AJW70177.1 - 0.0084 15.9 0.0 9.8 6.0 0.0 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4384) A2M_N_2 PF07703.9 AJW70177.1 - 0.036 13.8 0.0 1.2 8.9 0.0 3.1 3 0 0 3 3 3 0 Alpha-2-macroglobulin family N-terminal region AAA_15 PF13175.1 AJW70178.1 - 1.5e-19 70.3 6.8 1.5e-19 70.3 4.7 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 AJW70178.1 - 1.9e-11 44.4 12.5 1.9e-11 44.4 8.7 4.2 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AJW70178.1 - 0.00086 19.6 13.1 0.00086 19.6 9.1 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AJW70178.1 - 0.0022 18.2 1.5 0.0067 16.7 0.0 2.4 2 1 0 2 2 2 1 ABC transporter DUF2813 PF11398.3 AJW70178.1 - 0.0033 16.5 0.1 0.55 9.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2813) AAA_29 PF13555.1 AJW70178.1 - 0.0036 16.7 0.1 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Glyco_hydro_42C PF08533.5 AJW70178.1 - 0.016 14.7 0.1 0.7 9.4 0.0 2.9 2 1 1 3 3 3 0 Beta-galactosidase C-terminal domain SMC_N PF02463.14 AJW70178.1 - 0.072 12.3 0.0 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 AJW70178.1 - 0.11 12.4 0.0 0.4 10.6 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Plasmodium_HRP PF05403.6 AJW70180.1 - 2.8e-05 23.8 1.3 3.8e-05 23.3 0.9 1.1 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) RNA_pol_Rpc34 PF05158.7 AJW70180.1 - 0.00069 18.9 13.7 0.0018 17.5 9.4 1.9 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit DUF4573 PF15140.1 AJW70180.1 - 0.0085 15.7 11.2 0.015 14.9 7.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) MarR PF01047.17 AJW70180.1 - 0.015 14.9 0.2 0.035 13.8 0.1 1.6 1 0 0 1 1 1 0 MarR family RPA_C PF08784.6 AJW70180.1 - 0.035 14.5 0.2 0.12 12.8 0.2 2.0 1 1 0 1 1 1 0 Replication protein A C terminal PLRV_ORF5 PF01690.12 AJW70180.1 - 9.3 5.2 20.0 11 5.0 13.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FtsJ PF01728.14 AJW70181.1 - 1.8e-51 174.7 0.0 2.1e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 AJW70181.1 - 0.0002 21.0 0.1 0.00086 18.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW70181.1 - 0.0049 16.6 0.0 0.0094 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW70181.1 - 0.01 16.1 0.1 0.025 14.9 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 AJW70181.1 - 0.023 15.2 0.0 0.036 14.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 AJW70181.1 - 0.038 13.3 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 NOL1/NOP2/sun family CMAS PF02353.15 AJW70181.1 - 0.042 12.9 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TRM PF02005.11 AJW70182.1 - 6e-80 268.9 0.0 6.9e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 AJW70182.1 - 0.0028 17.2 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 AJW70182.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RNase_HII PF01351.13 AJW70183.1 - 1.7e-44 151.8 0.3 2e-44 151.6 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease HII Fibrillarin PF01269.12 AJW70184.1 - 3.2e-85 284.6 0.3 3.2e-85 284.6 0.2 2.9 2 1 0 2 2 2 1 Fibrillarin Methyltransf_18 PF12847.2 AJW70184.1 - 0.019 15.5 4.0 0.026 15.1 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain DUF3540 PF12059.3 AJW70184.1 - 0.053 13.1 10.5 1.2 8.7 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) Nop PF01798.13 AJW70185.1 - 5.3e-50 168.6 0.8 9.1e-50 167.8 0.5 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AJW70185.1 - 5.7e-20 70.8 0.0 1.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain PX PF00787.19 AJW70185.1 - 0.13 12.0 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 PX domain DHO_dh PF01180.16 AJW70186.1 - 5.9e-56 189.5 0.5 6.7e-56 189.4 0.4 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 AJW70186.1 - 1.1e-05 24.7 0.2 0.0039 16.4 0.0 2.5 3 0 0 3 3 3 2 Histidine biosynthesis protein Dus PF01207.12 AJW70186.1 - 0.00014 20.8 0.0 0.013 14.3 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF561 PF04481.7 AJW70186.1 - 0.00048 19.1 5.4 0.00064 18.7 0.0 3.2 3 1 0 4 4 4 1 Protein of unknown function (DUF561) ThiG PF05690.9 AJW70186.1 - 0.0011 18.1 0.5 0.5 9.4 0.1 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 AJW70186.1 - 0.0012 18.1 0.1 0.003 16.7 0.0 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AJW70186.1 - 0.0036 16.2 0.0 0.0078 15.1 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 AJW70186.1 - 0.071 12.3 0.3 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 PcrB family NAD_binding_1 PF00175.16 AJW70187.1 - 2.6e-16 60.1 0.0 4.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.4 AJW70187.1 - 3.9e-11 42.2 8.4 7.5e-11 41.3 5.8 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.19 AJW70187.1 - 8.5e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AJW70187.1 - 0.042 13.7 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DMRL_synthase PF00885.14 AJW70187.1 - 0.13 11.9 0.1 18 5.0 0.0 2.2 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Radical_SAM PF04055.16 AJW70188.1 - 2.3e-09 37.6 0.0 5.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S30 PF04758.9 AJW70189.1 - 6.4e-08 32.2 6.3 1.6e-07 30.9 4.4 1.8 1 1 0 1 1 1 1 Ribosomal protein S30 Rad51 PF08423.6 AJW70191.1 - 1.3e-92 309.3 0.1 1.8e-92 308.8 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AJW70191.1 - 8.2e-11 41.6 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AJW70191.1 - 2e-09 36.8 0.0 3.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 AJW70191.1 - 6.2e-09 35.3 0.1 9.5e-09 34.7 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 AJW70191.1 - 9.8e-09 35.2 0.4 2.5e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ABC_tran PF00005.22 AJW70191.1 - 0.018 15.3 0.1 0.08 13.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_31 PF13614.1 AJW70191.1 - 0.023 14.6 0.0 0.056 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 AJW70191.1 - 0.12 12.1 0.3 1.4 8.5 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase Radical_SAM PF04055.16 AJW70192.1 - 9.8e-15 55.1 0.1 1.9e-13 50.9 0.0 2.1 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 AJW70192.1 - 0.00014 21.8 0.0 0.0004 20.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJW70192.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Ribosomal_L21e PF01157.13 AJW70193.1 - 1.3e-14 53.7 1.5 1.7e-14 53.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_pol_Rpb4 PF03874.11 AJW70194.1 - 7.8e-14 51.6 0.9 2e-13 50.3 0.6 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF655 PF04919.7 AJW70195.1 - 2.9e-52 177.0 0.3 3.2e-52 176.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.1 AJW70195.1 - 9.5e-05 22.3 0.0 0.00027 20.9 0.0 1.7 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.2 AJW70195.1 - 0.0014 18.4 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif RrnaAD PF00398.15 AJW70196.1 - 6.2e-42 143.4 1.5 7.3e-42 143.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AJW70196.1 - 3.2e-05 23.9 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW70196.1 - 0.00011 22.7 0.0 0.00027 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJW70196.1 - 0.00029 20.4 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AJW70196.1 - 0.00053 19.5 0.9 0.0019 17.7 0.3 1.9 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 AJW70196.1 - 0.005 16.2 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 AJW70196.1 - 0.0084 15.8 0.0 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW70196.1 - 0.043 14.2 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 AJW70196.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 AJW70196.1 - 0.051 12.6 0.1 0.095 11.8 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 AJW70196.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNase_H_2 PF13482.1 AJW70196.1 - 0.07 12.9 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 RNase_H superfamily DOT1 PF08123.8 AJW70196.1 - 1.5 8.0 5.5 0.73 9.1 0.1 2.3 1 1 1 2 2 2 0 Histone methylation protein DOT1 MTS PF05175.9 AJW70197.1 - 1.1e-09 37.9 0.0 1.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AJW70197.1 - 1.1e-08 34.7 0.9 2e-08 33.9 0.6 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW70197.1 - 6.2e-07 29.2 0.0 3.7e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AJW70197.1 - 3.9e-05 23.6 0.0 8e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJW70197.1 - 0.00012 22.4 0.1 0.00022 21.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AJW70197.1 - 0.00012 21.1 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 AJW70197.1 - 0.00026 21.5 0.0 0.00048 20.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJW70197.1 - 0.00073 19.1 0.0 0.0029 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 AJW70197.1 - 0.00097 18.0 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.7 AJW70197.1 - 0.0019 18.6 0.1 0.0034 17.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AJW70197.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW70197.1 - 0.027 14.8 0.1 0.11 12.8 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 AJW70197.1 - 0.028 13.1 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 AJW70197.1 - 0.053 12.6 0.1 0.096 11.7 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 AJW70197.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 FtsJ PF01728.14 AJW70197.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 AJW70197.1 - 0.11 11.5 0.2 0.21 10.6 0.1 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Iso_dh PF00180.15 AJW70198.1 - 1e-81 274.6 0.2 1.2e-81 274.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos_2 PF12850.2 AJW70199.1 - 7.1e-21 74.6 0.1 9.6e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AJW70199.1 - 1e-16 60.9 0.1 1.4e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2124 PF09897.4 AJW70199.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) Metallophos_3 PF14582.1 AJW70199.1 - 0.00094 18.4 0.2 0.0079 15.3 0.0 2.1 1 1 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily OrfB_Zn_ribbon PF07282.6 AJW70200.1 - 0.0017 17.9 0.4 0.0018 17.8 0.2 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-RING_4 PF14570.1 AJW70200.1 - 0.053 13.1 3.7 3.2 7.4 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 AJW70200.1 - 0.064 12.8 0.7 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF4451 PF14616.1 AJW70200.1 - 0.091 12.5 2.3 0.41 10.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) PhnA_Zn_Ribbon PF08274.7 AJW70200.1 - 0.1 12.4 0.9 0.65 9.8 0.1 2.0 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.1 AJW70200.1 - 0.11 12.2 1.0 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.16 AJW70200.1 - 0.12 12.3 1.5 0.23 11.3 1.0 1.4 1 1 0 1 1 1 0 IBR domain zf-DBF PF07535.7 AJW70200.1 - 0.21 11.2 2.2 0.51 10.0 0.4 1.9 2 0 0 2 2 2 0 DBF zinc finger DZR PF12773.2 AJW70200.1 - 0.25 11.1 2.2 0.43 10.4 1.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.9 AJW70200.1 - 0.29 10.8 1.7 2.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.1 AJW70200.1 - 0.31 10.8 2.8 3.3 7.4 0.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 AJW70200.1 - 0.5 10.2 2.2 14 5.5 0.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 AJW70200.1 - 0.52 10.0 3.3 5 6.9 0.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Zn-ribbon_8 PF09723.5 AJW70200.1 - 0.54 10.2 3.9 9.8 6.2 1.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 AJW70200.1 - 1.2 8.8 4.5 7.1 6.3 0.3 2.0 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.10 AJW70201.1 - 0.00026 20.3 0.8 0.00031 20.1 0.6 1.1 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.16 AJW70201.1 - 0.0066 16.3 1.0 0.01 15.7 0.5 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AJW70201.1 - 0.0075 16.0 0.6 0.01 15.6 0.2 1.4 2 0 0 2 2 2 1 Basic region leucine zipper TSC22 PF01166.13 AJW70201.1 - 0.034 14.0 0.6 0.058 13.3 0.4 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 AJW70201.1 - 0.047 14.0 0.2 0.049 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Mto2_bdg PF12808.2 AJW70201.1 - 0.053 13.6 0.2 0.072 13.1 0.2 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CCDC144C PF14915.1 AJW70201.1 - 0.057 12.3 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region HAP1_N PF04849.8 AJW70201.1 - 0.11 11.3 0.2 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Chibby PF14645.1 AJW70201.1 - 0.14 12.0 0.2 0.17 11.7 0.2 1.3 1 1 0 1 1 1 0 Chibby family Transglut_core2 PF13369.1 AJW70202.1 - 8.1e-41 139.0 0.0 1.1e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.1 AJW70202.1 - 1.9e-16 59.6 0.0 2.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJW70202.1 - 7.7e-05 22.5 0.2 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 AJW70202.1 - 0.00036 20.0 0.4 0.11 12.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AJW70202.1 - 0.012 15.4 0.0 0.95 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Focal_AT PF03623.8 AJW70202.1 - 0.02 14.3 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region YfzA PF14118.1 AJW70202.1 - 0.049 13.7 0.1 2.4 8.3 0.1 2.4 2 0 0 2 2 2 0 YfzA-like protein TPR_12 PF13424.1 AJW70202.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 AJW70202.1 - 0.074 12.7 0.1 0.49 10.0 0.0 2.0 1 1 0 1 1 1 0 TPR repeat Herpes_UL74 PF07982.7 AJW70203.1 - 0.036 12.7 1.6 0.068 11.8 0.0 1.9 2 1 0 2 2 2 0 Herpes UL74 glycoproteins Methyltransf_23 PF13489.1 AJW70204.1 - 5.3e-06 26.2 0.0 1.5e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJW70204.1 - 1.2e-05 25.7 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Trm112p PF03966.11 AJW70204.1 - 3e-05 24.2 0.6 0.0001 22.6 0.3 2.0 2 0 0 2 2 2 1 Trm112p-like protein Methyltransf_31 PF13847.1 AJW70204.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain zf-CSL PF05207.8 AJW70204.1 - 0.0016 17.8 0.7 0.0029 17.0 0.5 1.4 1 0 0 1 1 1 1 CSL zinc finger Methyltransf_25 PF13649.1 AJW70204.1 - 0.0099 16.2 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW70204.1 - 0.01 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Zn_Tnp_IS1595 PF12760.2 AJW70204.1 - 0.013 15.2 0.3 0.027 14.2 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.8 AJW70204.1 - 0.017 14.7 0.3 0.059 13.0 0.1 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Methyltransf_18 PF12847.2 AJW70204.1 - 0.027 15.0 0.0 0.046 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNA_POL_M_15KD PF02150.11 AJW70204.1 - 0.14 11.9 0.2 9.9 5.9 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_5 PF13719.1 AJW70204.1 - 0.28 10.7 1.6 0.6 9.7 1.1 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Cupredoxin_1 PF13473.1 AJW70205.1 - 4.7e-06 26.4 0.1 6.5e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Cupredoxin-like domain DUF929 PF06053.6 AJW70205.1 - 0.23 10.5 1.5 0.25 10.3 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF929) REJ PF02010.10 AJW70206.1 - 0.041 12.2 0.4 0.07 11.4 0.1 1.5 2 0 0 2 2 2 0 REJ domain Thioredoxin_3 PF13192.1 AJW70208.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain SCIMP PF15050.1 AJW70208.1 - 0.16 11.8 0.6 0.26 11.1 0.4 1.3 1 1 0 1 1 1 0 SCIMP protein Band_7 PF01145.20 AJW70209.1 - 2.8e-24 86.0 7.9 4.1e-24 85.4 5.4 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2250 PF10007.4 AJW70210.1 - 0.008 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HxlR PF01638.12 AJW70210.1 - 0.019 14.5 0.1 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix TrmB PF01978.14 AJW70210.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 AJW70210.1 - 0.035 13.6 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit TFIIB PF00382.14 AJW70211.1 - 1.6e-30 104.6 7.9 1.6e-17 63.0 1.3 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW70211.1 - 3.8e-08 32.5 0.4 6.1e-08 31.8 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_AsnC-type PF13404.1 AJW70211.1 - 0.0016 17.9 0.1 0.014 14.9 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.7 AJW70211.1 - 0.0035 16.9 0.7 0.082 12.5 0.0 2.5 2 0 0 2 2 2 1 HTH domain Sigma70_r4 PF04545.11 AJW70211.1 - 0.0061 15.8 0.0 0.31 10.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.18 AJW70211.1 - 0.0066 16.0 0.4 0.091 12.3 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TetR_N PF00440.18 AJW70211.1 - 0.014 14.9 0.3 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family LacI PF00356.16 AJW70211.1 - 0.019 14.6 4.1 2.6 7.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.1 AJW70211.1 - 0.025 14.2 0.7 0.32 10.7 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_31 PF13560.1 AJW70211.1 - 0.045 13.9 0.4 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain zf-ribbon_3 PF13248.1 AJW70211.1 - 0.047 12.9 0.3 0.092 11.9 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HTH_24 PF13412.1 AJW70211.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.7 AJW70211.1 - 0.12 11.8 1.1 0.76 9.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 HrcA_DNA-bdg PF03444.10 AJW70211.1 - 0.13 11.6 1.4 2.7 7.4 0.0 2.7 3 0 0 3 3 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding FaeA PF04703.7 AJW70211.1 - 0.14 12.3 0.7 0.77 9.9 0.0 2.3 2 1 0 2 2 2 0 FaeA-like protein A2L_zn_ribbon PF08792.5 AJW70214.1 - 0.09 12.2 1.1 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_4 PF13894.1 AJW70214.1 - 0.48 10.8 8.1 3.3 8.2 0.6 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger Metallophos PF00149.23 AJW70215.1 - 7e-07 28.8 0.2 2.1e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 AJW70215.1 - 1.2e-06 28.5 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Response_reg PF00072.19 AJW70216.1 - 2.5e-21 75.7 0.0 2.9e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF2608 PF11019.3 AJW70216.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DEAD PF00270.24 AJW70217.1 - 2.1e-27 95.6 0.0 4e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AJW70217.1 - 7.7e-13 48.1 0.1 5.4e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AJW70217.1 - 1.9e-06 27.8 0.5 8e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1998 PF09369.5 AJW70217.1 - 1.2e-05 25.7 0.2 4.2e-05 24.0 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) HTH_20 PF12840.2 AJW70218.1 - 2.8e-08 33.4 0.0 2.3e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 AJW70218.1 - 2.4e-07 30.3 0.0 6.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_45 PF14947.1 AJW70218.1 - 8.1e-05 22.3 0.8 0.0025 17.6 0.1 2.7 3 0 0 3 3 3 1 Winged helix-turn-helix HTH_24 PF13412.1 AJW70218.1 - 9.7e-05 21.6 0.4 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 AJW70218.1 - 0.00012 22.3 0.2 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain DUF4423 PF14394.1 AJW70218.1 - 0.00012 21.6 0.4 0.00034 20.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) TrmB PF01978.14 AJW70218.1 - 0.00019 21.0 0.1 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 AJW70218.1 - 0.00028 20.5 0.9 0.077 12.7 0.0 2.3 2 0 0 2 2 2 2 MarR family DUF2250 PF10007.4 AJW70218.1 - 0.00045 20.0 0.8 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) Phage_rep_org_N PF09681.5 AJW70218.1 - 0.0012 18.3 0.3 0.0041 16.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal phage replisome organiser (Phage_rep_org_N) HTH_5 PF01022.15 AJW70218.1 - 0.0021 17.6 0.8 0.0046 16.5 0.0 2.0 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family Sulfolobus_pRN PF05584.6 AJW70218.1 - 0.013 15.4 0.3 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein Mrr_N PF14338.1 AJW70218.1 - 0.07 13.2 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Mrr N-terminal domain B-block_TFIIIC PF04182.7 AJW70218.1 - 0.072 12.9 1.7 1.5 8.6 0.0 3.0 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC Nitroreductase PF00881.19 AJW70219.1 - 8.5e-29 100.4 0.0 1.4e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family DUF2603 PF10788.4 AJW70219.1 - 0.017 14.9 0.5 0.046 13.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) DCP1 PF06058.8 AJW70219.1 - 0.049 13.6 0.1 0.72 9.9 0.0 2.6 3 0 0 3 3 3 0 Dcp1-like decapping family DUF1515 PF07439.6 AJW70220.1 - 0.13 12.0 0.2 0.13 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Gln-synt_C PF00120.19 AJW70225.1 - 2.1e-84 282.7 0.0 2.6e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AJW70225.1 - 8e-23 79.8 0.1 1.6e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4377 PF14302.1 AJW70228.1 - 8.5e-24 83.2 0.0 1.4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4377) Kazal_1 PF00050.16 AJW70228.1 - 4.1e-09 36.3 2.5 5.6e-09 35.8 0.8 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 AJW70228.1 - 4.8e-06 26.3 1.0 1.5e-05 24.7 0.7 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 AJW70228.1 - 3.7 7.4 6.6 2.7 7.9 2.2 2.7 2 1 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain SnoaL_3 PF13474.1 AJW70230.1 - 0.00046 20.2 0.0 0.00091 19.2 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 AJW70230.1 - 0.0068 15.9 0.1 0.022 14.3 0.1 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase LEH PF07858.7 AJW70230.1 - 0.029 14.3 0.1 0.27 11.2 0.0 2.0 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain PAH PF02671.16 AJW70231.1 - 0.022 14.3 0.4 0.026 14.1 0.3 1.4 1 1 0 1 1 1 0 Paired amphipathic helix repeat PHA_synth_III_E PF09712.5 AJW70232.1 - 0.0071 15.7 0.2 0.0079 15.6 0.2 1.0 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) EcsC PF12787.2 AJW70232.1 - 0.073 12.4 0.7 0.085 12.2 0.5 1.2 1 0 0 1 1 1 0 EcsC protein family DegQ PF08181.6 AJW70232.1 - 0.24 11.1 4.9 9.2 6.0 0.1 3.3 3 0 0 3 3 3 0 DegQ (SacQ) family NPHI_C PF08469.5 AJW70232.1 - 0.48 10.3 4.3 0.39 10.6 1.2 1.8 1 1 1 2 2 2 0 Nucleoside triphosphatase I C-terminal Pox_A14 PF05767.7 AJW70233.1 - 0.066 13.1 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 TRAM PF01938.15 AJW70233.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 TRAM domain IncA PF04156.9 AJW70235.1 - 0.039 13.5 9.3 0.32 10.5 0.3 2.3 2 0 0 2 2 2 0 IncA protein DUF302 PF03625.9 AJW70236.1 - 1.3e-19 69.4 0.0 3.1e-19 68.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF302 BACK PF07707.10 AJW70236.1 - 0.057 13.2 0.1 0.36 10.6 0.0 1.9 1 1 1 2 2 2 0 BTB And C-terminal Kelch Rhodanese PF00581.15 AJW70237.1 - 1.1e-26 93.4 0.0 1e-14 54.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain YjeF_N PF03853.10 AJW70237.1 - 0.088 12.4 0.0 0.69 9.5 0.0 2.2 3 0 0 3 3 3 0 YjeF-related protein N-terminus HTH_20 PF12840.2 AJW70238.1 - 4.4e-08 32.8 0.0 6.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 AJW70238.1 - 0.002 17.6 0.0 0.003 17.0 0.0 1.4 1 1 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 AJW70238.1 - 0.0062 15.8 0.2 0.039 13.3 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding Pox_int_trans PF05718.7 AJW70238.1 - 0.012 14.1 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor TrmB PF01978.14 AJW70238.1 - 0.013 15.1 0.1 0.039 13.6 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB SUD-M PF11633.3 AJW70238.1 - 0.018 14.3 0.1 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain DUF742 PF05331.6 AJW70238.1 - 0.04 13.5 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF742) tRNA_anti-codon PF01336.20 AJW70238.1 - 0.12 12.2 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Rad50_zn_hook PF04423.9 AJW70239.1 - 0.0045 16.4 0.2 0.0087 15.5 0.1 1.5 1 0 0 1 1 1 1 Rad50 zinc hook motif zinc_ribbon_2 PF13240.1 AJW70239.1 - 2.2 7.8 6.9 0.86 9.1 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-LSD1 PF06943.7 AJW70239.1 - 2.7 7.6 8.9 1.3 8.6 1.3 2.5 3 0 0 3 3 3 0 LSD1 zinc finger Arginase PF00491.16 AJW70241.1 - 1.7e-60 204.6 0.0 1.9e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 AJW70241.1 - 0.013 15.7 0.2 0.048 13.8 0.0 1.8 1 1 1 2 2 2 0 UPF0489 domain Aldedh PF00171.17 AJW70242.1 - 9.2e-137 456.1 0.0 1.3e-136 455.6 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AJW70242.1 - 0.019 13.7 0.0 0.055 12.1 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Pro_dh PF01619.13 AJW70243.1 - 2e-39 135.4 0.2 3.4e-39 134.6 0.1 1.3 1 1 0 1 1 1 1 Proline dehydrogenase HAUS4 PF14735.1 AJW70243.1 - 0.053 12.8 0.6 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 BOFC_N PF08977.5 AJW70243.1 - 0.27 11.0 1.5 4.1 7.3 0.2 2.5 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal B2-adapt-app_C PF09066.5 AJW70245.1 - 0.1 12.4 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain EMP24_GP25L PF01105.19 AJW70247.1 - 3.4e-05 23.6 1.8 3.4e-05 23.6 1.2 1.6 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD CarboxypepD_reg PF13620.1 AJW70247.1 - 0.00015 21.7 0.2 0.00026 20.9 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4294 PF14127.1 AJW70248.1 - 0.0038 16.8 3.7 0.0063 16.1 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) Herpes_UL14 PF03580.9 AJW70248.1 - 0.014 15.2 0.8 0.027 14.2 0.6 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ALMT PF11744.3 AJW70248.1 - 0.025 13.2 2.2 0.027 13.1 1.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PEPcase PF00311.12 AJW70248.1 - 0.026 12.4 2.3 0.027 12.3 1.6 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF4065 PF13274.1 AJW70248.1 - 0.53 11.0 3.7 0.41 11.3 1.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) Med28 PF11594.3 AJW70248.1 - 0.55 10.4 8.5 0.73 10.0 4.0 2.1 1 1 1 2 2 2 0 Mediator complex subunit 28 ATP-synt_F6 PF05511.6 AJW70248.1 - 0.57 10.1 7.0 4.8 7.1 4.9 2.3 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Acetyltransf_11 PF13720.1 AJW70248.1 - 1.1 9.5 3.4 3.9 7.7 0.0 2.8 1 1 2 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 COX16 PF14138.1 AJW70248.1 - 1.3 9.2 5.9 1.1 9.4 2.6 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 RGS PF00615.14 AJW70248.1 - 4.6 7.3 10.3 22 5.1 0.1 2.3 1 1 0 2 2 2 0 Regulator of G protein signaling domain SurA_N_2 PF13623.1 AJW70248.1 - 4.8 7.1 11.1 6.2 6.7 5.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain A2M_N PF01835.14 AJW70249.1 - 3.2e-21 75.4 0.7 6.5e-05 23.1 0.0 4.4 4 0 0 4 4 4 4 MG2 domain FlgD_ig PF13860.1 AJW70249.1 - 1.3e-05 24.8 1.3 0.065 12.9 0.0 4.5 3 1 2 5 5 5 2 FlgD Ig-like domain Cna_B PF05738.8 AJW70249.1 - 0.00045 19.9 5.8 0.43 10.3 0.0 4.3 4 0 0 4 4 4 2 Cna protein B-type domain Wzt_C PF14524.1 AJW70249.1 - 0.0034 17.0 1.2 4 7.1 0.0 3.8 4 0 0 4 4 4 2 Wzt C-terminal domain DUF3244 PF11589.3 AJW70249.1 - 0.0037 16.9 5.8 0.88 9.3 0.1 4.4 2 1 3 5 5 5 2 Domain of unknown function (DUF3244) DUF4198 PF10670.4 AJW70249.1 - 0.0055 16.7 0.1 0.5 10.3 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4198) SLAC1 PF03595.12 AJW70250.1 - 0.02 13.5 2.2 0.022 13.4 1.5 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF373 PF04123.8 AJW70250.1 - 0.028 13.4 2.9 0.034 13.1 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF981 PF06168.6 AJW70250.1 - 0.053 13.3 2.2 0.075 12.7 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) ER_lumen_recept PF00810.13 AJW70250.1 - 0.087 13.3 2.3 0.12 12.8 1.6 1.2 1 0 0 1 1 1 0 ER lumen protein retaining receptor TrbE PF11100.3 AJW70250.1 - 3 7.7 6.8 6.4 6.7 0.2 2.6 1 1 2 3 3 3 0 Conjugal transfer protein TrbE HTH_24 PF13412.1 AJW70251.1 - 2.4e-19 68.4 2.0 2.4e-10 39.6 0.0 2.7 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 AJW70251.1 - 2.2e-14 52.8 1.3 5.2e-09 35.6 0.2 2.5 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJW70251.1 - 1.5e-13 50.3 0.0 6.2e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain TrmB PF01978.14 AJW70251.1 - 1.3e-12 47.2 0.1 4.4e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 AJW70251.1 - 2.8e-09 36.5 0.3 8.7e-05 22.1 0.1 2.3 2 0 0 2 2 2 2 MarR family MarR_2 PF12802.2 AJW70251.1 - 7.3e-09 35.1 0.0 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 2 MarR family HTH_34 PF13601.1 AJW70251.1 - 4e-08 33.1 0.2 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain HTH_11 PF08279.7 AJW70251.1 - 1.4e-07 31.0 0.0 0.00053 19.5 0.0 2.2 2 0 0 2 2 2 2 HTH domain FaeA PF04703.7 AJW70251.1 - 1.5e-07 31.4 0.1 0.00026 21.0 0.0 3.0 2 1 1 3 3 3 1 FaeA-like protein HTH_IclR PF09339.5 AJW70251.1 - 8.3e-07 28.5 0.0 0.0062 16.1 0.0 2.2 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_27 PF13463.1 AJW70251.1 - 6.4e-06 26.3 0.0 0.00055 20.2 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain LexA_DNA_bind PF01726.11 AJW70251.1 - 6.9e-06 25.5 0.6 0.12 11.9 0.0 3.2 3 2 1 4 4 3 2 LexA DNA binding domain GerE PF00196.14 AJW70251.1 - 6.6e-05 22.1 0.1 0.01 15.1 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family RepL PF05732.6 AJW70251.1 - 0.00013 21.2 0.0 0.015 14.5 0.0 2.3 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) HTH_Crp_2 PF13545.1 AJW70251.1 - 0.00023 20.8 0.0 0.0066 16.2 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Mga PF05043.8 AJW70251.1 - 0.00028 21.0 0.2 0.96 9.7 0.0 2.4 1 1 1 2 2 2 2 Mga helix-turn-helix domain HTH_10 PF04967.7 AJW70251.1 - 0.00029 20.3 0.1 0.088 12.4 0.0 2.9 3 0 0 3 3 2 1 HTH DNA binding domain HTH_36 PF13730.1 AJW70251.1 - 0.00034 20.6 0.4 0.18 11.9 0.0 2.7 3 0 0 3 3 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 AJW70251.1 - 0.00044 19.5 0.0 0.0014 17.8 0.0 1.8 2 0 0 2 2 1 1 Sigma-70, region 4 HTH_AsnC-type PF13404.1 AJW70251.1 - 0.0007 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_9 PF08221.6 AJW70251.1 - 0.00091 19.0 0.1 0.0047 16.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF4423 PF14394.1 AJW70251.1 - 0.00094 18.7 0.1 0.2 11.1 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4423) Penicillinase_R PF03965.11 AJW70251.1 - 0.0012 18.9 1.6 0.011 15.8 0.2 2.4 1 1 1 2 2 2 1 Penicillinase repressor Sigma70_r4_2 PF08281.7 AJW70251.1 - 0.0025 17.2 0.0 0.029 13.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Rrf2 PF02082.15 AJW70251.1 - 0.0033 17.5 0.2 0.09 12.9 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator HTH_23 PF13384.1 AJW70251.1 - 0.0033 17.0 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Mga PF08280.6 AJW70251.1 - 0.0037 16.9 0.1 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain Crp PF00325.15 AJW70251.1 - 0.004 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_40 PF14493.1 AJW70251.1 - 0.006 16.7 0.1 0.88 9.8 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 AJW70251.1 - 0.0077 15.7 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIE_alpha PF02002.12 AJW70251.1 - 0.012 15.0 0.5 4.1 6.9 0.1 2.5 1 1 1 2 2 2 0 TFIIE alpha subunit Fe_dep_repress PF01325.14 AJW70251.1 - 0.019 14.9 0.1 0.56 10.1 0.0 2.5 2 1 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_41 PF14502.1 AJW70251.1 - 0.019 14.5 0.0 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4364 PF14277.1 AJW70251.1 - 0.023 14.3 1.4 0.35 10.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) FUR PF01475.14 AJW70251.1 - 0.03 14.2 1.8 0.38 10.6 0.1 2.4 2 1 0 2 2 2 0 Ferric uptake regulator family HTH_45 PF14947.1 AJW70251.1 - 0.032 14.0 2.2 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix PaaX PF07848.7 AJW70251.1 - 0.035 14.1 0.0 5.9 6.9 0.0 2.4 2 1 0 2 2 2 0 PaaX-like protein LacI PF00356.16 AJW70251.1 - 0.035 13.7 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 1 0 Bacterial regulatory proteins, lacI family FeoC PF09012.5 AJW70251.1 - 0.041 13.5 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_29 PF13551.1 AJW70251.1 - 0.043 13.9 0.0 0.83 9.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix TetR_N PF00440.18 AJW70251.1 - 0.063 12.9 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Peptidase_C39 PF03412.10 AJW70251.1 - 0.068 12.9 0.2 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase C39 family MerR_1 PF13411.1 AJW70251.1 - 0.088 12.5 0.8 0.53 10.0 0.0 2.2 2 1 0 2 2 2 0 MerR HTH family regulatory protein DUF2250 PF10007.4 AJW70251.1 - 0.091 12.6 0.6 8.6 6.3 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) KorB PF08535.5 AJW70251.1 - 0.12 12.5 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 KorB domain Toxin_59 PF15537.1 AJW70251.1 - 0.14 12.1 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 59 TSP_3 PF02412.13 AJW70252.1 - 3.8e-11 42.2 39.6 8.9e-06 25.0 3.2 3.8 3 0 0 3 3 3 3 Thrombospondin type 3 repeat CorA PF01544.13 AJW70253.1 - 0.0067 15.5 2.8 0.01 14.8 1.9 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TRAP_alpha PF03896.11 AJW70253.1 - 0.0067 15.4 5.1 0.009 15.0 3.5 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit IncA PF04156.9 AJW70253.1 - 0.017 14.7 2.9 0.057 13.0 1.9 1.7 2 0 0 2 2 2 0 IncA protein DUF1510 PF07423.6 AJW70253.1 - 0.023 14.0 2.3 0.026 13.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pedibin PF08182.6 AJW70253.1 - 0.027 13.9 0.7 0.049 13.1 0.5 1.5 1 0 0 1 1 1 0 Pedibin/Hym-346 family DUF972 PF06156.8 AJW70253.1 - 0.064 13.6 1.3 0.095 13.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 AJW70253.1 - 0.068 12.6 3.8 0.12 11.8 2.6 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF2205 PF10224.4 AJW70253.1 - 0.093 12.3 2.4 0.25 10.9 1.6 1.7 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 AJW70253.1 - 0.16 11.7 4.2 0.3 10.9 2.9 1.6 1 1 0 1 1 1 0 Basic region leucine zipper Tetraspannin PF00335.15 AJW70253.1 - 0.24 10.6 0.8 0.51 9.5 0.5 1.7 1 1 0 1 1 1 0 Tetraspanin family Med4 PF10018.4 AJW70253.1 - 0.32 10.3 3.8 0.44 9.9 2.6 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 FlxA PF14282.1 AJW70253.1 - 0.95 9.4 6.4 1.7 8.6 4.5 1.5 1 0 0 1 1 1 0 FlxA-like protein CDC45 PF02724.9 AJW70253.1 - 4.1 5.3 15.0 4.8 5.0 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein UPF0060 PF02694.10 AJW70254.1 - 1.9e-37 127.5 7.2 2.1e-37 127.3 5.0 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EmrE PF13536.1 AJW70254.1 - 8.5e-06 25.9 5.2 2.4e-05 24.5 3.6 1.6 1 1 0 1 1 1 1 Multidrug resistance efflux transporter MFS_1 PF07690.11 AJW70254.1 - 0.0002 20.1 6.0 0.0022 16.7 0.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EamA PF00892.15 AJW70254.1 - 0.0013 18.7 6.4 0.0026 17.8 4.4 1.5 1 1 0 1 1 1 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.6 AJW70254.1 - 0.0072 16.0 6.2 0.023 14.4 4.3 1.7 1 1 0 1 1 1 1 7TM diverse intracellular signalling PMT_2 PF13231.1 AJW70254.1 - 0.011 15.6 3.3 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Acyl_transf_3 PF01757.17 AJW70254.1 - 0.092 11.5 6.8 0.12 11.2 4.7 1.1 1 0 0 1 1 1 0 Acyltransferase family Multi_Drug_Res PF00893.14 AJW70254.1 - 0.23 11.9 3.6 0.23 11.9 1.9 1.5 1 1 0 1 1 1 0 Small Multidrug Resistance protein UPF0060 PF02694.10 AJW70255.1 - 2.8e-40 136.6 9.5 3.3e-40 136.4 6.6 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.15 AJW70255.1 - 0.001 19.0 11.6 0.0022 17.9 8.0 1.6 1 1 0 1 1 1 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.6 AJW70255.1 - 0.005 16.5 5.0 0.0076 15.9 3.5 1.3 1 0 0 1 1 1 1 7TM diverse intracellular signalling EmrE PF13536.1 AJW70255.1 - 0.025 14.7 7.1 0.035 14.2 4.9 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Bax1-I PF01027.15 AJW70255.1 - 0.055 13.0 5.2 0.069 12.7 3.6 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 QCR10 PF09796.4 AJW70255.1 - 0.11 12.1 0.7 0.25 11.0 0.3 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Frag1 PF10277.4 AJW70255.1 - 0.41 10.0 7.4 0.72 9.2 5.1 1.7 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family MFS_1 PF07690.11 AJW70255.1 - 0.61 8.7 13.4 4.8 5.8 9.6 1.8 1 1 0 1 1 1 0 Major Facilitator Superfamily Multi_Drug_Res PF00893.14 AJW70255.1 - 0.73 10.3 6.7 0.58 10.6 3.7 1.5 1 1 1 2 2 2 0 Small Multidrug Resistance protein DUF3611 PF12263.3 AJW70255.1 - 8.6 5.7 6.5 11 5.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) HTH_AsnC-type PF13404.1 AJW70258.1 - 1e-11 44.1 0.1 1.5e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AJW70258.1 - 3.2e-11 42.4 0.3 6e-11 41.5 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 AJW70258.1 - 4.8e-05 22.9 0.0 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 AJW70258.1 - 0.00011 22.0 0.3 0.00059 19.6 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 AJW70258.1 - 0.00019 21.0 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 AJW70258.1 - 0.00028 20.5 1.5 0.00062 19.4 0.0 2.3 3 0 0 3 3 3 1 FeoC like transcriptional regulator HTH_27 PF13463.1 AJW70258.1 - 0.00055 20.1 0.1 0.0094 16.2 0.0 2.1 1 1 1 2 2 2 1 Winged helix DNA-binding domain DUF4423 PF14394.1 AJW70258.1 - 0.00071 19.1 0.2 0.00097 18.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_Tnp_ISL3 PF13542.1 AJW70258.1 - 0.00072 18.6 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Arc_trans_TRASH PF08394.5 AJW70258.1 - 0.0017 18.4 4.6 0.0031 17.6 3.2 1.5 1 0 0 1 1 1 1 Archaeal TRASH domain DUF2089 PF09862.4 AJW70258.1 - 0.0049 16.6 0.3 0.051 13.3 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2089) HTH_9 PF08221.6 AJW70258.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain MarR_2 PF12802.2 AJW70258.1 - 0.0065 16.1 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.1 AJW70258.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.17 AJW70258.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 MarR family ATPase-cat_bd PF12156.3 AJW70258.1 - 0.028 14.9 1.2 0.059 13.9 0.8 1.6 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-FCS PF06467.9 AJW70258.1 - 0.031 13.9 3.3 0.058 13.0 2.3 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HTH_34 PF13601.1 AJW70258.1 - 0.048 13.7 0.1 0.18 11.8 0.0 1.8 1 1 1 2 2 2 0 Winged helix DNA-binding domain NUMOD1 PF07453.8 AJW70258.1 - 0.091 12.6 0.4 2 8.3 0.0 2.5 2 0 0 2 2 2 0 NUMOD1 domain HTH_20 PF12840.2 AJW70258.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4396 PF14342.1 AJW70259.1 - 2.3e-27 95.8 4.6 2.7e-27 95.5 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF2269 PF10027.4 AJW70259.1 - 0.094 12.4 2.8 0.11 12.3 1.4 1.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DoxX PF07681.7 AJW70261.1 - 1.1e-08 35.4 1.9 1.1e-08 35.4 1.3 1.9 2 0 0 2 2 2 1 DoxX DoxD PF04173.8 AJW70261.1 - 3e-05 23.7 1.5 3e-05 23.7 1.0 1.6 2 0 0 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.1 AJW70261.1 - 0.18 11.8 2.4 0.37 10.7 1.6 1.7 1 1 0 1 1 1 0 DoxX-like family Dr_adhesin PF12393.3 AJW70261.1 - 5.3 7.2 5.8 0.41 10.7 0.5 1.9 2 0 0 2 2 2 0 Dr family adhesin DUF642 PF04862.7 AJW70263.1 - 8e-21 74.3 0.1 1.2e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF642) CBM_4_9 PF02018.12 AJW70263.1 - 0.00092 19.2 0.5 0.0024 17.8 0.4 1.7 1 1 0 1 1 1 1 Carbohydrate binding domain FG-GAP PF01839.18 AJW70263.1 - 0.041 13.5 5.6 0.12 12.1 2.5 2.7 1 1 1 2 2 2 0 FG-GAP repeat VCBS PF13517.1 AJW70263.1 - 0.08 13.3 1.0 0.21 11.9 0.2 2.2 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TSP_3 PF02412.13 AJW70264.1 - 8.8e-05 21.9 6.4 8.8e-05 21.9 4.5 3.5 3 1 0 3 3 3 2 Thrombospondin type 3 repeat VWA PF00092.23 AJW70265.1 - 9.3e-22 77.5 2.0 2.8e-21 76.0 0.3 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain HYR PF02494.11 AJW70265.1 - 1.1e-21 76.6 28.7 6.7e-11 42.0 1.6 4.3 4 0 0 4 4 4 3 HYR domain Big_3_4 PF13754.1 AJW70265.1 - 2.6e-06 27.6 38.9 0.027 14.7 6.6 5.1 4 0 0 4 4 4 3 Bacterial Ig-like domain (group 3) Big_3_2 PF12245.3 AJW70265.1 - 3.2e-05 23.4 2.8 0.1 12.1 0.0 3.8 3 0 0 3 3 3 2 Bacterial Ig-like domain (group 3) DUF4398 PF14346.1 AJW70265.1 - 0.0005 20.0 6.7 0.0005 20.0 4.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) DUF4175 PF13779.1 AJW70265.1 - 0.0054 14.5 0.7 0.0083 13.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) HrcA PF01628.16 AJW70265.1 - 0.032 13.8 0.3 0.066 12.7 0.2 1.5 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF2895 PF11444.3 AJW70267.1 - 0.026 13.7 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Branch PF02485.16 AJW70267.1 - 0.04 13.0 0.2 0.057 12.5 0.2 1.2 1 0 0 1 1 1 0 Core-2/I-Branching enzyme DHDPS PF00701.17 AJW70268.1 - 0.045 12.3 0.0 0.075 11.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family HTH_45 PF14947.1 AJW70270.1 - 1.9e-05 24.4 1.0 2.5e-05 23.9 0.7 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 AJW70270.1 - 0.046 13.4 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 AJW70270.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 MarR family RE_HaeII PF09554.5 AJW70270.1 - 0.092 11.7 0.1 0.091 11.7 0.1 1.0 1 0 0 1 1 1 0 HaeII restriction endonuclease SHOCT PF09851.4 AJW70271.1 - 0.00019 20.7 0.4 0.00043 19.6 0.3 1.6 1 0 0 1 1 1 1 Short C-terminal domain CcmH PF03918.9 AJW70271.1 - 0.016 14.2 0.0 0.026 13.4 0.0 1.4 1 1 0 1 1 1 0 Cytochrome C biogenesis protein DUF4199 PF13858.1 AJW70271.1 - 0.019 14.9 0.1 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) GvpG PF05120.7 AJW70271.1 - 0.033 13.9 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle protein G HJURP_C PF12347.3 AJW70271.1 - 0.15 11.6 6.2 0.42 10.2 0.4 2.6 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat DUF106 PF01956.11 AJW70271.1 - 0.18 11.3 4.2 0.77 9.2 0.7 2.2 2 1 0 2 2 2 0 Integral membrane protein DUF106 SecY PF00344.15 AJW70272.1 - 0.12 11.2 11.0 0.16 10.8 7.6 1.1 1 0 0 1 1 1 0 SecY translocase ATP_synt_I PF03899.10 AJW70272.1 - 2.3 8.4 10.7 0.75 9.9 4.8 1.9 1 1 1 2 2 2 0 ATP synthase I chain DUF2975 PF11188.3 AJW70272.1 - 2.7 7.7 9.3 0.49 10.1 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) SdpI PF13630.1 AJW70272.1 - 5.6 6.7 13.3 3.9 7.2 1.4 2.3 1 1 1 2 2 2 0 SdpI/YhfL protein family Cu-oxidase_3 PF07732.10 AJW70273.1 - 2.7e-24 85.1 4.0 6e-24 84.0 0.1 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AJW70273.1 - 4.3e-17 61.8 3.9 3.2e-06 26.6 0.0 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 AJW70273.1 - 1.5e-08 34.4 0.0 0.0019 18.0 0.0 3.5 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.15 AJW70273.1 - 2.5e-07 30.8 3.1 0.00014 22.0 0.5 3.5 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase PF00394.17 AJW70273.1 - 3.9e-05 23.5 0.1 0.00057 19.8 0.0 2.4 2 1 1 3 3 3 1 Multicopper oxidase Herpes_UL6 PF01763.11 AJW70274.1 - 0.037 12.2 0.0 0.043 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like HicB PF05534.7 AJW70274.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 HicB family EcoR124_C PF12008.3 AJW70275.1 - 0.092 11.9 1.6 0.39 9.8 0.1 2.1 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF3829 PF12889.2 AJW70275.1 - 0.11 11.6 0.1 0.13 11.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) AsnC_trans_reg PF01037.16 AJW70276.1 - 5.9e-09 35.5 0.0 7.1e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 AsnC family zf-C2H2_2 PF12756.2 AJW70277.1 - 9.1e-05 22.5 0.5 9.1e-05 22.5 0.4 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AJW70277.1 - 0.0015 18.7 0.8 0.0032 17.7 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AJW70277.1 - 0.0037 17.4 0.5 0.006 16.8 0.4 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.10 AJW70277.1 - 0.023 14.4 0.5 0.036 13.8 0.3 1.5 1 0 0 1 1 1 0 BED zinc finger zf-met PF12874.2 AJW70277.1 - 0.027 14.6 0.5 0.071 13.3 0.4 1.7 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_3 PF13878.1 AJW70277.1 - 0.049 13.2 0.2 0.074 12.6 0.2 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO zf-H2C2_2 PF13465.1 AJW70277.1 - 1.7 9.0 5.6 5.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain HTH_45 PF14947.1 AJW70278.1 - 2.1e-06 27.4 0.1 3.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 AJW70278.1 - 0.0003 20.4 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 AJW70278.1 - 0.024 14.6 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2513 PF10711.4 AJW70278.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_Crp_2 PF13545.1 AJW70278.1 - 0.13 12.0 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain IncA PF04156.9 AJW70283.1 - 0.015 14.9 3.5 0.015 14.9 2.4 1.7 2 0 0 2 2 2 0 IncA protein CorA PF01544.13 AJW70283.1 - 0.021 13.8 4.1 0.035 13.1 2.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1510 PF07423.6 AJW70283.1 - 0.03 13.6 6.4 0.051 12.9 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) bZIP_2 PF07716.10 AJW70283.1 - 0.062 13.1 2.7 0.12 12.1 1.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF972 PF06156.8 AJW70283.1 - 0.092 13.0 1.7 0.16 12.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 AJW70283.1 - 0.12 12.3 2.3 0.19 11.7 1.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor FlaC_arch PF05377.6 AJW70283.1 - 0.12 12.2 1.9 0.17 11.8 0.8 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) TPD52 PF04201.10 AJW70283.1 - 0.12 12.0 1.3 0.19 11.4 0.9 1.2 1 0 0 1 1 1 0 Tumour protein D52 family DivIC PF04977.10 AJW70283.1 - 0.18 11.3 3.5 0.37 10.3 2.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Cauli_AT PF03233.8 AJW70283.1 - 0.33 10.6 2.7 0.45 10.2 1.9 1.2 1 0 0 1 1 1 0 Aphid transmission protein TRAP_alpha PF03896.11 AJW70283.1 - 0.65 8.9 22.6 0.11 11.5 3.6 2.2 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FlxA PF14282.1 AJW70283.1 - 0.68 9.9 7.7 1.2 9.1 5.3 1.4 1 0 0 1 1 1 0 FlxA-like protein Tetraspannin PF00335.15 AJW70283.1 - 4.6 6.4 6.1 7.9 5.6 3.2 2.2 1 1 0 1 1 1 0 Tetraspanin family AsiA PF09010.5 AJW70285.1 - 0.05 13.4 0.7 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 Anti-Sigma Factor A DUF3279 PF11682.3 AJW70285.1 - 0.056 13.0 0.7 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3279) DUF718 PF05336.8 AJW70285.1 - 0.099 12.4 0.9 0.95 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF718) Cupredoxin_1 PF13473.1 AJW70286.1 - 0.00013 21.7 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 AJW70286.1 - 0.0021 18.2 0.1 0.01 16.0 0.0 2.2 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family MlrC_C PF07171.7 AJW70286.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 MlrC C-terminus BNR_2 PF13088.1 AJW70287.1 - 2.9e-08 33.3 0.1 0.00044 19.6 0.0 3.6 1 1 1 3 3 3 3 BNR repeat-like domain Glyco_hydro_43 PF04616.9 AJW70287.1 - 5.4e-06 25.6 4.2 0.00037 19.6 0.0 3.2 1 1 2 3 3 3 2 Glycosyl hydrolases family 43 BNR PF02012.15 AJW70287.1 - 0.68 9.9 22.7 17 5.7 0.1 7.3 7 0 0 7 7 7 0 BNR/Asp-box repeat DUF624 PF04854.9 AJW70289.1 - 0.065 13.1 1.3 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 VRP3 PF03536.10 AJW70289.1 - 0.072 12.2 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein zf-C2H2_4 PF13894.1 AJW70291.1 - 0.015 15.5 1.0 0.026 14.8 0.7 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 AJW70291.1 - 0.03 14.5 1.2 0.062 13.5 0.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain YokU PF14122.1 AJW70291.1 - 0.11 12.1 0.2 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 YokU-like protein DUF2065 PF09838.4 AJW70295.1 - 0.045 13.4 2.5 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) CcmD PF04995.9 AJW70295.1 - 0.15 11.8 0.6 0.15 11.8 0.4 2.2 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) RseC_MucC PF04246.7 AJW70295.1 - 1.5 8.4 4.7 30 4.1 3.2 2.2 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FixQ PF05545.6 AJW70295.1 - 3.1 7.5 6.6 5.7 6.6 0.9 2.8 2 1 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF2127 PF09900.4 AJW70295.1 - 6.1 6.8 11.3 1.7 8.6 5.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2127) SH PF01445.12 AJW70296.1 - 0.041 13.5 0.6 0.041 13.5 0.4 1.9 2 0 0 2 2 2 0 Viral small hydrophobic protein DUF3923 PF13061.1 AJW70296.1 - 0.072 12.9 2.7 2.3 8.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) ATP-synt_8 PF00895.15 AJW70296.1 - 1.8 8.8 5.8 0.51 10.5 1.6 1.9 1 1 1 2 2 2 0 ATP synthase protein 8 Phage_int_SAM_3 PF14659.1 AJW70298.1 - 0.023 14.9 0.4 0.051 13.8 0.3 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HTH_24 PF13412.1 AJW70298.1 - 0.084 12.2 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2608 PF11019.3 AJW70302.1 - 0.018 14.0 0.2 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) BNR PF02012.15 AJW70304.1 - 0.0074 15.9 0.9 18 5.6 0.0 4.2 3 0 0 3 3 3 2 BNR/Asp-box repeat Tetraspannin PF00335.15 AJW70305.1 - 0.054 12.7 1.1 0.064 12.5 0.1 1.5 2 0 0 2 2 2 0 Tetraspanin family zf-FCS PF06467.9 AJW70306.1 - 0.024 14.2 3.5 0.85 9.3 0.8 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.1 AJW70306.1 - 0.06 12.5 0.1 0.06 12.5 0.0 2.3 3 0 0 3 3 3 0 zinc-ribbon domain CsiD PF08943.5 AJW70306.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 CsiD zinc_ribbon_2 PF13240.1 AJW70306.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain RAMP PF04901.8 AJW70307.1 - 0.15 11.8 0.5 11 5.7 0.2 2.3 2 0 0 2 2 2 0 Receptor activity modifying family CcoS PF03597.10 AJW70307.1 - 0.46 9.9 2.3 0.86 9.1 1.6 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type CBM_14 PF01607.19 AJW70309.1 - 0.0018 18.1 8.9 0.58 10.1 0.3 3.7 1 1 2 3 3 3 3 Chitin binding Peritrophin-A domain DUF4215 PF13948.1 AJW70309.1 - 2.8 8.2 10.2 2.7 8.3 1.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) Tad PF13400.1 AJW70310.1 - 3.8 7.6 4.9 1.6 8.7 0.4 2.0 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF3430 PF11912.3 AJW70311.1 - 0.048 13.4 3.0 0.073 12.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Topoisom_I_N PF02919.10 AJW70312.1 - 1.2e-70 237.2 8.6 1.2e-70 237.2 5.9 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AJW70312.1 - 3.4e-64 216.1 14.1 3.4e-64 216.1 9.8 2.2 1 1 1 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 AJW70312.1 - 9.5e-22 76.4 1.3 9.5e-22 76.4 0.9 3.9 3 1 2 5 5 5 1 C-terminal topoisomerase domain Neur_chan_memb PF02932.11 AJW70312.1 - 3.3 7.5 9.3 0.38 10.6 3.2 1.8 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region adh_short PF00106.20 AJW70313.1 - 4.3e-29 101.5 0.0 5.3e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AJW70313.1 - 4.7e-21 75.6 0.0 5.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AJW70313.1 - 3.3e-10 39.9 0.0 4.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 AJW70313.1 - 7e-06 25.3 0.0 2.4e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 AJW70313.1 - 1.1e-05 24.8 0.1 0.0011 18.3 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family Eno-Rase_NADH_b PF12242.3 AJW70313.1 - 0.002 17.8 0.1 0.0045 16.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DHquinase_II PF01220.14 AJW70313.1 - 0.013 14.7 0.1 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Dehydroquinase class II DEAD PF00270.24 AJW70314.1 - 5.8e-32 110.4 0.2 2e-31 108.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AJW70314.1 - 2.8e-13 49.5 0.3 1.1e-11 44.3 0.1 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 AJW70314.1 - 2.9e-12 46.9 0.1 7.5e-12 45.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.10 AJW70314.1 - 3.8e-06 26.8 1.5 6e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AJW70314.1 - 0.0082 14.9 0.6 0.011 14.5 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain N6_N4_Mtase PF01555.13 AJW70315.1 - 1.6e-37 129.2 3.5 1.9e-37 129.0 2.4 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 AJW70315.1 - 3.3e-08 33.5 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.13 AJW70315.1 - 4.4e-05 23.1 0.0 0.16 11.5 0.0 2.3 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 AJW70315.1 - 0.0008 18.5 0.1 0.11 11.5 0.1 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase MethyltransfD12 PF02086.10 AJW70315.1 - 0.0026 17.2 0.2 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase MttA_Hcf106 PF02416.11 AJW70316.1 - 1.1e-09 37.1 0.8 1.8e-09 36.5 0.6 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family IFT20 PF14931.1 AJW70316.1 - 0.0019 18.1 0.7 0.0024 17.7 0.5 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF948 PF06103.6 AJW70316.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) VIT1 PF01988.14 AJW70316.1 - 0.061 12.8 0.1 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 VIT family TraG-D_C PF12696.2 AJW70316.1 - 0.1 12.4 0.5 1.6 8.5 0.2 2.1 1 1 1 2 2 2 0 TraM recognition site of TraD and TraG DUF972 PF06156.8 AJW70316.1 - 0.12 12.7 0.8 0.15 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PCYCGC PF13798.1 AJW70316.1 - 0.14 11.8 0.6 0.52 9.9 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function with PCYCGC motif P-II PF00543.17 AJW70317.1 - 1.1e-17 64.3 1.2 1.9e-17 63.6 0.8 1.4 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II CaM-KIIN PF15170.1 AJW70317.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor MFS_1 PF07690.11 AJW70318.1 - 2.1e-41 141.8 59.0 1.3e-33 116.2 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2985 PF11204.3 AJW70318.1 - 0.036 13.8 4.9 0.47 10.2 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) DUF1228 PF06779.9 AJW70318.1 - 0.27 11.2 11.6 0.078 13.0 0.9 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) YwiC PF14256.1 AJW70318.1 - 0.86 9.6 7.5 2.3 8.3 0.9 3.0 2 1 0 2 2 2 0 YwiC-like protein Ubie_methyltran PF01209.13 AJW70319.1 - 2.8e-18 65.8 0.0 3.5e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AJW70319.1 - 2.3e-13 50.4 0.0 3.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW70319.1 - 8.2e-08 32.8 0.0 1.3e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW70319.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW70319.1 - 2.4e-07 30.4 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW70319.1 - 1.4e-06 28.6 0.0 2.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW70319.1 - 3e-06 27.5 0.0 4.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AJW70319.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 AJW70319.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AJW70319.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 AJW70319.1 - 0.099 11.7 0.0 0.19 10.7 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Proteasome PF00227.21 AJW70320.1 - 1.8e-50 170.8 0.8 2.3e-50 170.5 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AJW70320.1 - 6.8e-13 47.6 1.5 3.1e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature SUKH-3 PF14433.1 AJW70320.1 - 0.041 13.6 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 SUKH-3 immunity protein HTH_5 PF01022.15 AJW70321.1 - 1.3e-10 40.7 0.2 3.5e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJW70321.1 - 1.7e-06 27.6 0.0 4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AJW70321.1 - 0.0013 18.0 0.1 0.0013 18.0 0.1 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding B-block_TFIIIC PF04182.7 AJW70321.1 - 0.0017 18.1 0.4 0.0029 17.4 0.1 1.6 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC TrmB PF01978.14 AJW70321.1 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.5 AJW70321.1 - 0.0049 16.5 0.1 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain MarR PF01047.17 AJW70321.1 - 0.0056 16.3 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_45 PF14947.1 AJW70321.1 - 0.0057 16.4 0.2 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 AJW70321.1 - 0.01 15.4 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 MarR family DUF4423 PF14394.1 AJW70321.1 - 0.014 14.9 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_Crp_2 PF13545.1 AJW70321.1 - 0.017 14.8 0.0 0.33 10.7 0.0 2.3 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Phage_rep_org_N PF09681.5 AJW70321.1 - 0.022 14.2 0.4 0.036 13.6 0.2 1.3 1 1 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) BLOC1_2 PF10046.4 AJW70321.1 - 0.054 13.6 1.7 0.097 12.8 1.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HTH_34 PF13601.1 AJW70321.1 - 0.059 13.4 0.2 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain HxlR PF01638.12 AJW70321.1 - 0.068 12.8 0.1 0.11 12.0 0.1 1.4 1 1 0 1 1 1 0 HxlR-like helix-turn-helix HTH_11 PF08279.7 AJW70321.1 - 0.09 12.4 0.2 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_23 PF13384.1 AJW70321.1 - 0.091 12.4 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Fe_dep_repress PF01325.14 AJW70321.1 - 0.13 12.2 0.0 4.2 7.3 0.0 2.1 1 1 1 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain ELFV_dehydrog PF00208.16 AJW70322.1 - 7.7e-69 231.9 2.5 1.1e-68 231.4 1.7 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 AJW70322.1 - 1.9e-46 156.8 0.0 3.5e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Carot_N PF09150.5 AJW70322.1 - 0.13 11.9 0.0 13 5.4 0.0 2.6 3 0 0 3 3 3 0 Orange carotenoid protein, N-terminal AlaDh_PNT_C PF01262.16 AJW70322.1 - 0.48 9.9 2.9 2.8 7.4 1.5 2.4 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Toprim PF01751.17 AJW70323.1 - 7.5e-05 22.6 0.1 0.00029 20.7 0.1 1.9 1 1 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 AJW70323.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.5 1 1 0 1 1 1 1 Toprim domain FCH PF00611.18 AJW70323.1 - 0.043 14.0 0.2 0.066 13.4 0.1 1.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Toprim_3 PF13362.1 AJW70323.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 Toprim domain GATase PF00117.23 AJW70324.1 - 2.9e-23 82.3 0.0 4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJW70324.1 - 2.2e-06 27.3 0.0 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 HTS PF04204.11 AJW70324.1 - 1.3e-05 24.1 0.0 8.4e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 Homoserine O-succinyltransferase DJ-1_PfpI PF01965.19 AJW70324.1 - 0.034 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.9 AJW70324.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Phage_integrase PF00589.17 AJW70325.1 - 5.2e-10 39.2 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family HxlR PF01638.12 AJW70326.1 - 1.8e-23 81.9 0.0 2.2e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.9 AJW70326.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.2 AJW70326.1 - 0.0043 16.8 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AJW70326.1 - 0.0082 15.5 0.1 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJW70326.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_12 PF08461.5 AJW70326.1 - 0.031 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Cas_VVA1548 PF09652.5 AJW70326.1 - 0.037 14.0 0.0 0.46 10.5 0.0 2.0 1 1 1 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) MtrA PF04208.9 AJW70326.1 - 0.051 13.0 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A HTH_27 PF13463.1 AJW70326.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain ADH_zinc_N PF00107.21 AJW70327.1 - 0.042 13.3 0.1 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF935 PF06074.7 AJW70327.1 - 0.061 12.0 0.1 0.062 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Atg14 PF10186.4 AJW70327.1 - 0.063 12.2 0.7 0.074 11.9 0.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 AJW70328.1 - 8.6e-07 28.8 1.0 0.0014 18.4 0.0 2.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 AJW70328.1 - 7.4e-06 26.0 11.7 0.1 12.8 8.3 3.6 1 1 2 3 3 3 2 Syntaxin Reo_sigmaC PF04582.7 AJW70328.1 - 0.00034 19.9 5.5 0.0013 17.9 2.2 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Spc7 PF08317.6 AJW70328.1 - 0.00056 18.6 6.2 0.00056 18.6 4.3 2.0 2 1 0 2 2 2 1 Spc7 kinetochore protein AAA_13 PF13166.1 AJW70328.1 - 0.002 16.6 10.1 0.0053 15.2 7.0 1.6 1 1 0 1 1 1 1 AAA domain TrbC PF04956.8 AJW70328.1 - 0.0025 17.7 0.2 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF1664 PF07889.7 AJW70328.1 - 0.0034 17.1 18.6 1.8 8.3 8.1 4.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Tweety PF04906.8 AJW70328.1 - 0.0039 15.6 0.3 0.006 15.0 0.2 1.2 1 0 0 1 1 1 1 Tweety IFT57 PF10498.4 AJW70328.1 - 0.0046 15.7 5.4 0.018 13.8 3.8 1.9 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DHC_N2 PF08393.8 AJW70328.1 - 0.0063 15.0 1.4 0.0063 15.0 0.2 1.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 FTR_C PF02741.10 AJW70328.1 - 0.0067 16.2 7.9 0.039 13.7 2.5 2.3 1 1 1 2 2 2 1 FTR, proximal lobe Syntaxin-6_N PF09177.6 AJW70328.1 - 0.013 15.9 11.3 1.2 9.5 2.4 3.4 2 1 2 4 4 3 0 Syntaxin 6, N-terminal DUF4618 PF15397.1 AJW70328.1 - 0.013 14.8 3.2 0.098 11.9 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) JHBP PF06585.6 AJW70328.1 - 0.014 14.1 1.6 0.32 9.7 0.0 2.7 1 1 1 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) Prominin PF05478.6 AJW70328.1 - 0.015 12.8 7.0 0.025 12.1 4.1 1.6 1 1 1 2 2 2 0 Prominin TMPIT PF07851.8 AJW70328.1 - 0.02 13.9 2.4 0.031 13.3 1.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF759 PF05537.6 AJW70328.1 - 0.021 13.6 10.6 0.53 8.9 0.2 2.3 1 1 1 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) DUF4083 PF13314.1 AJW70328.1 - 0.022 14.5 0.6 0.022 14.5 0.4 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4083) TACC PF05010.9 AJW70328.1 - 0.022 14.5 0.9 0.028 14.2 0.6 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) IMD PF08397.6 AJW70328.1 - 0.022 14.0 2.4 0.15 11.3 1.6 2.0 1 1 1 2 2 2 0 IRSp53/MIM homology domain Tho2 PF11262.3 AJW70328.1 - 0.025 13.6 2.6 17 4.3 4.2 2.5 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF1640 PF07798.6 AJW70328.1 - 0.037 14.0 6.1 0.24 11.4 4.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) TBPIP PF07106.8 AJW70328.1 - 0.052 13.0 11.4 1 8.8 3.1 2.5 2 1 1 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apolipoprotein PF01442.13 AJW70328.1 - 0.07 12.6 0.0 0.59 9.6 0.1 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Kinetocho_Slk19 PF12709.2 AJW70328.1 - 0.072 13.1 1.4 0.35 10.9 0.3 2.5 1 1 1 2 2 2 0 Central kinetochore-associated COG5 PF10392.4 AJW70328.1 - 0.09 12.7 6.0 1.9 8.4 0.3 3.0 2 1 1 3 3 2 0 Golgi transport complex subunit 5 FH2 PF02181.18 AJW70328.1 - 0.093 11.5 4.4 0.55 9.0 3.0 2.1 1 1 0 1 1 1 0 Formin Homology 2 Domain APG17 PF04108.7 AJW70328.1 - 0.095 11.4 7.2 0.73 8.5 0.1 2.2 1 1 2 3 3 3 0 Autophagy protein Apg17 AAA_32 PF13654.1 AJW70328.1 - 0.13 10.9 3.4 0.45 9.1 2.2 1.7 1 1 0 2 2 2 0 AAA domain Fib_alpha PF08702.5 AJW70328.1 - 0.17 12.0 10.8 0.18 11.9 4.6 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Lzipper-MIP1 PF14389.1 AJW70328.1 - 0.21 11.7 4.2 21 5.3 1.9 3.2 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF677 PF05055.7 AJW70328.1 - 0.23 10.0 15.3 0.26 9.9 9.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Lectin_N PF03954.9 AJW70328.1 - 0.26 10.6 1.8 1.1 8.5 1.2 2.2 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Phasin PF05597.6 AJW70328.1 - 0.28 10.9 7.8 1.7 8.4 3.7 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) COG7 PF10191.4 AJW70328.1 - 0.31 8.9 4.6 0.54 8.0 2.8 1.5 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) HsbA PF12296.3 AJW70328.1 - 0.32 10.8 9.3 15 5.4 5.7 3.2 2 1 0 2 2 1 0 Hydrophobic surface binding protein A GLTP PF08718.6 AJW70328.1 - 0.32 11.0 3.4 1.1 9.2 2.3 2.1 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) V_ATPase_I PF01496.14 AJW70328.1 - 0.35 8.6 5.6 0.3 8.8 3.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Cytochrom_B562 PF07361.6 AJW70328.1 - 0.35 11.2 3.0 0.63 10.4 0.8 2.1 1 1 1 2 2 2 0 Cytochrome b562 V-SNARE PF05008.10 AJW70328.1 - 0.44 10.7 3.6 2.4 8.3 0.8 2.9 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Sec5 PF15469.1 AJW70328.1 - 0.54 9.9 8.3 4.8 6.8 3.6 3.0 2 1 0 2 2 2 0 Exocyst complex component Sec5 Cauli_AT PF03233.8 AJW70328.1 - 0.54 9.9 13.5 1.1 8.9 6.2 2.5 1 1 2 3 3 3 0 Aphid transmission protein Zw10 PF06248.8 AJW70328.1 - 0.55 8.3 8.4 0.53 8.3 5.0 1.5 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 ISG65-75 PF11727.3 AJW70328.1 - 0.55 9.2 10.3 1.4 7.9 2.1 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1451 PF07295.6 AJW70328.1 - 0.58 9.9 2.8 2.2 8.0 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) GP41 PF00517.12 AJW70328.1 - 0.76 9.2 5.5 2.5 7.6 0.4 2.6 1 1 1 2 2 2 0 Retroviral envelope protein YlbD_coat PF14071.1 AJW70328.1 - 0.93 9.5 4.2 3.8 7.5 1.6 2.5 1 1 1 2 2 2 0 Putative coat protein DUF948 PF06103.6 AJW70328.1 - 1 9.2 15.4 5.7 6.8 5.8 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.6 AJW70328.1 - 1.1 8.4 4.2 2.3 7.4 2.9 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF2203 PF09969.4 AJW70328.1 - 1.2 9.3 4.0 4 7.6 2.5 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ACCA PF03255.9 AJW70328.1 - 1.4 8.5 4.9 24 4.4 0.0 2.7 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2130 PF09903.4 AJW70328.1 - 1.7 7.2 14.2 0.29 9.8 4.0 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) HN PF00423.14 AJW70328.1 - 2 6.5 6.6 1.1 7.4 2.6 1.9 2 0 0 2 2 2 0 Haemagglutinin-neuraminidase DUF2674 PF10879.3 AJW70328.1 - 2.1 8.1 8.3 3.5 7.4 0.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2674) MCPsignal PF00015.16 AJW70328.1 - 2.4 7.6 16.4 0.44 10.0 8.1 2.1 2 1 0 2 2 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MCP_N PF05581.7 AJW70328.1 - 4.3 7.5 11.1 1.4 9.1 0.1 3.2 1 1 2 3 3 3 0 Vibrio chemotaxis protein N terminus FlaC_arch PF05377.6 AJW70328.1 - 4.8 7.1 29.0 1.5 8.7 7.9 5.1 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 AJW70328.1 - 4.8 7.3 18.0 5.1 7.3 5.2 3.8 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.1 AJW70328.1 - 4.9 7.2 11.6 4.4 7.4 4.2 2.8 2 1 1 3 3 2 0 Syntaxin-like protein Laminin_I PF06008.9 AJW70328.1 - 5.3 6.2 8.5 1.3 8.2 2.3 2.2 2 1 0 2 2 2 0 Laminin Domain I CsbD PF05532.7 AJW70328.1 - 6.6 6.4 6.6 9.5 5.9 0.3 3.0 2 1 1 3 3 3 0 CsbD-like DUF730 PF05325.6 AJW70328.1 - 7.4 6.3 7.5 18 5.1 1.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF730) MtrG PF04210.8 AJW70328.1 - 9.7 5.9 15.0 0.31 10.7 2.5 3.5 1 1 2 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G zf-C4H2 PF10146.4 AJW70328.1 - 9.9 6.1 8.0 19 5.1 5.6 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein HTH_45 PF14947.1 AJW70332.1 - 7.1e-05 22.5 0.2 9.2e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.1 AJW70332.1 - 0.00017 20.9 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJW70332.1 - 0.0059 16.2 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 MarR family Peptidase_M10 PF00413.19 AJW70333.1 - 3.1e-06 26.9 0.1 3.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Matrixin Dak1_2 PF13684.1 AJW70334.1 - 0.049 12.5 2.2 0.04 12.8 0.4 1.6 2 0 0 2 2 2 0 Dihydroxyacetone kinase family DUF4307 PF14155.1 AJW70334.1 - 0.12 12.1 0.8 8.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Arch_flagellin PF01917.11 AJW70334.1 - 0.42 10.2 7.3 0.62 9.6 4.9 1.5 1 1 0 1 1 1 0 Archaebacterial flagellin P63C PF10546.4 AJW70336.1 - 0.12 12.2 0.6 0.22 11.4 0.1 1.6 2 0 0 2 2 2 0 P63C domain SRP-alpha_N PF04086.8 AJW70336.1 - 0.14 11.4 0.6 0.17 11.2 0.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PIG-Y PF15159.1 AJW70337.1 - 0.0011 19.1 3.1 0.0011 19.1 2.1 2.2 2 2 0 2 2 2 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y CBM_14 PF01607.19 AJW70341.1 - 0.00012 21.9 5.1 0.45 10.4 0.2 3.5 1 1 2 3 3 3 3 Chitin binding Peritrophin-A domain DUF4215 PF13948.1 AJW70341.1 - 0.21 11.8 5.8 0.44 10.8 2.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4215) Rer1 PF03248.8 AJW70342.1 - 0.011 15.3 0.1 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Rer1 family 7TM_GPCR_Srw PF10324.4 AJW70342.1 - 0.015 14.4 0.2 0.076 12.1 0.1 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw EphA2_TM PF14575.1 AJW70342.1 - 0.13 12.7 0.3 18 5.8 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3671 PF12420.3 AJW70342.1 - 2.1 8.3 5.5 25 4.9 3.8 2.5 1 1 0 1 1 1 0 Protein of unknown function CDC48_N PF02359.13 AJW70343.1 - 1.4e-06 28.1 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Molydop_binding PF01568.16 AJW70343.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Pik1 PF11522.3 AJW70343.1 - 0.069 12.9 0.2 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 ATP-grasp_5 PF13549.1 AJW70347.1 - 4.8e-69 231.9 0.3 7e-69 231.4 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 AJW70347.1 - 5.7e-48 162.0 0.2 1.4e-47 160.8 0.2 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AJW70347.1 - 6.1e-26 90.8 0.0 2.4e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.14 AJW70347.1 - 6.3e-10 39.4 0.5 2.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 AJW70347.1 - 2.3e-08 33.6 0.3 4.9e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AJW70347.1 - 0.0021 17.8 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain TPP_enzyme_M PF00205.17 AJW70347.1 - 0.0069 16.1 0.5 1.5 8.5 0.0 3.6 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, central domain ATP-grasp PF02222.17 AJW70347.1 - 0.031 13.6 0.0 0.069 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 AJW70347.1 - 0.046 13.1 0.1 0.16 11.4 0.1 1.9 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ECH PF00378.15 AJW70348.1 - 9.3e-73 244.3 1.2 1.1e-72 244.1 0.9 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AJW70348.1 - 0.0098 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Copper-bind PF00127.15 AJW70349.1 - 6.7e-09 35.8 0.0 1.5e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW70349.1 - 3.5e-06 26.8 0.0 8.5e-06 25.6 0.0 1.7 2 1 0 2 2 2 1 Cupredoxin-like domain DUF2431 PF10354.4 AJW70349.1 - 0.019 14.9 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) HTH_20 PF12840.2 AJW70350.1 - 3.2e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AJW70350.1 - 0.0002 20.9 0.1 0.00032 20.3 0.1 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FUR PF01475.14 AJW70350.1 - 0.0003 20.7 0.2 0.00036 20.4 0.1 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family Hpr_kinase_N PF02603.11 AJW70350.1 - 0.014 15.0 0.3 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 HPr Serine kinase N terminus HTH_IclR PF09339.5 AJW70350.1 - 0.015 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_40 PF14493.1 AJW70350.1 - 0.046 13.9 0.2 0.14 12.4 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain Fe-S_biosyn PF01521.15 AJW70351.1 - 2.1e-22 79.1 0.0 2.4e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0181 PF03701.9 AJW70351.1 - 0.11 11.7 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Toprim_4 PF13662.1 AJW70352.1 - 2.1e-06 27.6 0.2 4.7e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.17 AJW70352.1 - 0.0029 17.5 0.1 0.0076 16.2 0.1 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 AJW70352.1 - 0.041 14.1 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 Toprim-like Copper-fist PF00649.13 AJW70352.1 - 0.043 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain CTP-dep_RFKase PF01982.11 AJW70353.1 - 1.9e-43 146.9 0.0 3e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF120 HTH_36 PF13730.1 AJW70353.1 - 0.012 15.6 0.8 0.012 15.6 0.6 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain CTP_transf_2 PF01467.21 AJW70354.1 - 1.4e-13 51.2 0.1 2.9e-13 50.1 0.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase HTH_45 PF14947.1 AJW70354.1 - 6.3e-05 22.7 0.5 0.00012 21.8 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix FAD_syn PF06574.7 AJW70354.1 - 0.061 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 FAD synthetase TP_methylase PF00590.15 AJW70355.1 - 1.7e-18 67.0 0.0 1.8e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.8 AJW70355.1 - 2e-11 43.4 0.1 5.7e-11 41.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF357) Ala_racemase_C PF00842.16 AJW70355.1 - 0.036 13.4 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Peptidase_M20 PF01546.23 AJW70356.1 - 2.3e-31 108.7 0.1 2.9e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AJW70356.1 - 1.6e-13 50.3 0.2 3.5e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 AJW70356.1 - 1.1e-05 24.3 0.3 0.087 11.5 0.0 2.4 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase RimK PF08443.6 AJW70357.1 - 5.6e-43 146.6 0.0 7.5e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 AJW70357.1 - 3.9e-10 39.7 0.0 5.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.11 AJW70357.1 - 1.4e-07 30.8 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.9 AJW70357.1 - 5.1e-07 29.7 0.0 7.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AJW70357.1 - 1.4e-05 24.0 0.0 6.4e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 AJW70357.1 - 0.0048 16.2 0.0 0.0095 15.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 AJW70357.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.1 AJW70357.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain zinc_ribbon_5 PF13719.1 AJW70358.1 - 2.3e-07 30.2 3.0 0.00029 20.3 0.5 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJW70358.1 - 6.5e-07 28.9 4.1 0.00049 19.7 0.9 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 AJW70358.1 - 0.00039 19.5 0.3 0.017 14.3 0.0 2.1 2 0 0 2 2 2 1 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 AJW70358.1 - 0.00039 20.1 8.2 0.0028 17.3 2.5 1.9 1 1 1 2 2 2 2 PhnA Zinc-Ribbon Prok-RING_1 PF14446.1 AJW70358.1 - 0.00047 19.8 1.6 0.0011 18.6 1.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 AJW70358.1 - 0.00074 19.4 0.9 0.0011 18.9 0.6 1.2 1 0 0 1 1 1 1 zinc-finger zf-HYPF PF07503.7 AJW70358.1 - 0.00096 18.5 1.2 0.0072 15.7 0.8 1.9 1 1 0 1 1 1 1 HypF finger UPF0547 PF10571.4 AJW70358.1 - 0.0013 18.3 1.4 0.47 10.1 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zf-C4_Topoisom PF01396.14 AJW70358.1 - 0.0017 17.8 0.5 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger DNA_RNApol_7kD PF03604.8 AJW70358.1 - 0.0031 16.9 2.7 0.01 15.3 1.9 1.8 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 AJW70358.1 - 0.0092 15.4 1.5 0.076 12.4 0.1 2.0 2 0 0 2 2 2 1 A2L zinc ribbon domain DZR PF12773.2 AJW70358.1 - 0.012 15.4 1.1 0.022 14.5 0.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 AJW70358.1 - 0.013 15.1 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.14 AJW70358.1 - 0.014 15.0 0.4 0.015 14.9 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AJW70358.1 - 0.015 15.2 2.5 0.025 14.5 1.8 1.4 1 1 0 1 1 1 0 Zinc ribbon domain CpXC PF14353.1 AJW70358.1 - 0.019 14.9 0.5 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 CpXC protein zinc_ribbon_2 PF13240.1 AJW70358.1 - 0.02 14.3 3.1 0.25 10.8 2.1 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-CSL PF05207.8 AJW70358.1 - 0.026 14.0 2.1 0.033 13.6 1.3 1.4 1 1 0 1 1 1 0 CSL zinc finger RRN7 PF11781.3 AJW70358.1 - 0.032 13.7 2.3 0.038 13.5 0.1 1.9 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TerY-C PF15616.1 AJW70358.1 - 0.038 13.9 0.4 0.054 13.4 0.2 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain zf-C2H2_6 PF13912.1 AJW70358.1 - 0.053 13.4 1.1 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger BssC_TutF PF08201.6 AJW70358.1 - 0.06 12.8 0.1 6.1 6.4 0.0 2.0 2 0 0 2 2 2 0 BssC/TutF protein Lar_restr_allev PF14354.1 AJW70358.1 - 0.073 13.3 1.6 0.33 11.2 1.1 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF164 PF02591.10 AJW70358.1 - 0.12 12.1 3.0 0.79 9.5 2.1 2.0 1 1 0 1 1 1 0 Putative zinc ribbon domain COX5B PF01215.14 AJW70358.1 - 0.13 11.9 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb DUF35_N PF12172.3 AJW70358.1 - 0.14 12.1 0.6 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ogr_Delta PF04606.7 AJW70358.1 - 0.18 11.5 1.3 1.8 8.2 0.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger TF_Zn_Ribbon PF08271.7 AJW70358.1 - 0.18 11.1 3.0 0.36 10.1 2.1 1.5 1 1 1 2 2 2 0 TFIIB zinc-binding RNA_POL_M_15KD PF02150.11 AJW70358.1 - 0.23 11.1 1.9 1.7 8.4 1.3 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-IS66 PF13005.2 AJW70358.1 - 0.28 11.1 2.1 1.2 9.1 0.2 2.3 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF329 PF03884.9 AJW70358.1 - 0.34 10.4 1.7 0.77 9.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF329) DUF3797 PF12677.2 AJW70358.1 - 0.38 10.4 1.8 0.93 9.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-H2C2_2 PF13465.1 AJW70358.1 - 0.49 10.7 2.3 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain DUF1272 PF06906.6 AJW70358.1 - 1.8 8.5 4.5 6.2 6.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-dskA_traR PF01258.12 AJW70358.1 - 5.2 6.8 6.8 16 5.3 0.7 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger HMGL-like PF00682.14 AJW70359.1 - 4e-63 213.2 0.0 5.8e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like DUF1629 PF07791.6 AJW70359.1 - 0.12 12.2 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1629) HTH_AsnC-type PF13404.1 AJW70360.1 - 5.9e-13 48.1 0.0 1.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 AJW70360.1 - 1.2e-12 47.3 0.3 1.7e-12 46.8 0.2 1.2 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 AJW70360.1 - 7.9e-12 44.3 0.1 1.3e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding ACT_4 PF13291.1 AJW70360.1 - 0.0016 18.7 0.3 1.9 8.8 0.1 2.2 2 0 0 2 2 2 2 ACT domain HTH_11 PF08279.7 AJW70360.1 - 0.0058 16.2 0.4 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 HTH domain HTH_Tnp_ISL3 PF13542.1 AJW70360.1 - 0.0064 15.6 0.0 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Mga PF05043.8 AJW70360.1 - 0.0085 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Mga helix-turn-helix domain MarR_2 PF12802.2 AJW70360.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 MarR family Sigma70_r4 PF04545.11 AJW70360.1 - 0.012 14.9 0.0 0.032 13.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.14 AJW70360.1 - 0.012 15.2 0.9 0.17 11.6 0.1 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 AJW70360.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator NapD PF03927.8 AJW70360.1 - 0.017 14.9 0.8 0.027 14.2 0.5 1.3 1 0 0 1 1 1 0 NapD protein MarR PF01047.17 AJW70360.1 - 0.024 14.3 0.2 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_27 PF13463.1 AJW70360.1 - 0.026 14.8 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain DDRGK PF09756.4 AJW70360.1 - 0.033 13.5 0.8 0.076 12.4 0.1 1.8 2 0 0 2 2 2 0 DDRGK domain HTH_5 PF01022.15 AJW70360.1 - 0.039 13.6 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_IclR PF09339.5 AJW70360.1 - 0.048 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_9 PF08221.6 AJW70360.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF977 PF06163.6 AJW70360.1 - 0.085 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_DeoR PF08220.7 AJW70360.1 - 0.086 12.3 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Aminotran_3 PF00202.16 AJW70361.1 - 1.8e-105 352.5 0.1 2.2e-105 352.2 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AJW70361.1 - 0.00015 20.8 0.0 0.0017 17.3 0.0 1.9 1 1 1 2 2 2 1 Aminotransferase class I and II DUF2931 PF11153.3 AJW70361.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) Aminotran_5 PF00266.14 AJW70361.1 - 0.096 11.4 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V AA_kinase PF00696.23 AJW70362.1 - 8.3e-36 123.7 3.6 9.3e-36 123.5 2.5 1.0 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.19 AJW70363.1 - 6.4e-35 120.0 0.0 1e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 AJW70363.1 - 2.7e-17 63.2 0.0 5.3e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 AJW70363.1 - 9.2e-05 22.3 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 AJW70363.1 - 0.00047 19.2 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 AJW70363.1 - 0.00086 19.8 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.1 AJW70363.1 - 0.037 14.0 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding RimK PF08443.6 AJW70364.1 - 4.5e-44 150.1 0.0 5.8e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 AJW70364.1 - 1e-14 54.6 0.0 2.2e-14 53.5 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.11 AJW70364.1 - 4.8e-10 38.8 0.0 6.5e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_Ter PF15632.1 AJW70364.1 - 3.4e-09 35.9 0.0 5.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AJW70364.1 - 6.7e-08 32.5 0.0 1.8e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AJW70364.1 - 1.2e-07 31.2 0.0 7.1e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AJW70364.1 - 0.00021 20.8 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_YheCD PF14398.1 AJW70364.1 - 0.00025 19.9 0.0 0.029 13.1 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp CPSase_L_D2 PF02786.12 AJW70364.1 - 0.0016 17.7 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 AJW70364.1 - 0.0029 16.9 0.0 0.96 8.7 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 AJW70364.1 - 0.011 14.9 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.1 AJW70364.1 - 0.092 11.8 0.0 0.4 9.7 0.0 2.0 2 1 0 2 2 2 0 Sugar-transfer associated ATP-grasp zinc_ribbon_5 PF13719.1 AJW70365.1 - 2.5e-06 26.9 0.7 0.024 14.2 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJW70365.1 - 5e-06 26.1 0.7 0.043 13.5 0.0 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 AJW70365.1 - 0.00048 19.2 1.0 0.49 9.6 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AJW70365.1 - 0.00049 19.3 1.5 0.00078 18.7 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 AJW70365.1 - 0.00075 18.9 1.8 0.24 10.8 0.1 2.7 2 1 1 3 3 3 1 DNA directed RNA polymerase, 7 kDa subunit UPF0547 PF10571.4 AJW70365.1 - 0.0014 18.2 3.6 0.012 15.2 2.5 2.0 1 1 0 1 1 1 1 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.11 AJW70365.1 - 0.0033 17.0 0.4 0.0051 16.4 0.3 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit DNA_ligase_ZBD PF03119.11 AJW70365.1 - 0.0048 16.5 1.6 0.49 10.1 0.1 2.3 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain zf-HYPF PF07503.7 AJW70365.1 - 0.005 16.2 2.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 1 HypF finger zf-TFIIB PF13453.1 AJW70365.1 - 0.0058 15.7 1.8 0.12 11.5 2.2 1.9 1 1 1 2 2 2 2 Transcription factor zinc-finger DZR PF12773.2 AJW70365.1 - 0.0087 15.8 0.6 0.015 15.1 0.4 1.5 1 1 0 1 1 1 1 Double zinc ribbon Lar_restr_allev PF14354.1 AJW70365.1 - 0.0097 16.1 2.0 0.016 15.4 1.4 1.4 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-C4_Topoisom PF01396.14 AJW70365.1 - 0.0097 15.3 1.4 1.7 8.2 0.0 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger HypA PF01155.14 AJW70365.1 - 0.0097 15.5 0.3 0.011 15.4 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 AJW70365.1 - 0.01 15.5 4.1 0.027 14.2 2.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.5 AJW70365.1 - 0.011 15.1 1.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1 PF03811.8 AJW70365.1 - 0.015 14.8 1.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 InsA N-terminal domain zinc_ribbon_2 PF13240.1 AJW70365.1 - 0.015 14.7 0.4 0.087 12.3 0.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AJW70365.1 - 0.019 14.6 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 AJW70365.1 - 0.022 14.5 0.7 0.057 13.2 0.5 1.7 1 1 0 1 1 1 0 zinc-ribbons Ogr_Delta PF04606.7 AJW70365.1 - 0.022 14.3 0.5 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-IS66 PF13005.2 AJW70365.1 - 0.025 14.5 1.4 2.5 8.1 0.2 2.3 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-RING_3 PF14369.1 AJW70365.1 - 0.028 14.3 4.1 0.075 13.0 2.9 1.7 1 1 0 1 1 1 0 zinc-finger DUF2387 PF09526.5 AJW70365.1 - 0.03 14.2 0.3 0.036 13.9 0.2 1.2 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF164 PF02591.10 AJW70365.1 - 0.045 13.5 0.7 1.4 8.8 0.1 2.4 3 0 0 3 3 2 0 Putative zinc ribbon domain DUF329 PF03884.9 AJW70365.1 - 0.048 13.2 2.0 1.5 8.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF329) CpXC PF14353.1 AJW70365.1 - 0.071 13.0 0.2 3.1 7.7 0.0 2.1 2 0 0 2 2 2 0 CpXC protein ADK_lid PF05191.9 AJW70365.1 - 0.074 12.7 0.7 1.8 8.3 0.1 2.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-CSL PF05207.8 AJW70365.1 - 0.096 12.2 2.6 0.13 11.7 0.1 2.0 1 1 1 2 2 2 0 CSL zinc finger PAAR_motif PF05488.8 AJW70365.1 - 0.1 12.6 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 PAAR motif Zn-ribbon_8 PF09723.5 AJW70365.1 - 0.11 12.4 3.8 0.6 10.1 2.7 1.9 1 1 0 1 1 1 0 Zinc ribbon domain TerY-C PF15616.1 AJW70365.1 - 0.17 11.8 1.4 1.1 9.1 0.9 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain PhnA_Zn_Ribbon PF08274.7 AJW70365.1 - 0.21 11.4 3.9 3.2 7.6 0.0 2.2 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Rubredoxin PF00301.15 AJW70365.1 - 1.9 8.3 7.3 3.6 7.5 0.4 2.5 1 1 1 2 2 2 0 Rubredoxin Arginosuc_synth PF00764.14 AJW70366.1 - 6.8e-159 529.0 0.2 7.8e-159 528.8 0.1 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AJW70366.1 - 9.6e-07 28.5 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJW70366.1 - 0.00018 20.8 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 AJW70366.1 - 0.1 12.1 0.1 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PP-loop family NMT1_2 PF13379.1 AJW70367.1 - 4.2e-29 101.6 0.0 5.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.6 AJW70367.1 - 2.4e-13 50.1 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 AJW70367.1 - 2.6e-06 27.0 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein ABC_tran PF00005.22 AJW70368.1 - 3.2e-31 108.4 0.0 5.9e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJW70368.1 - 3.8e-11 43.4 0.0 2.6e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 AJW70368.1 - 0.0012 18.9 0.1 0.0025 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 AJW70368.1 - 0.0017 18.5 0.1 0.05 13.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AJW70368.1 - 0.0026 18.5 0.2 0.0053 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 AJW70368.1 - 0.0045 16.1 0.0 0.17 10.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 AJW70368.1 - 0.0063 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AJW70368.1 - 0.0065 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AJW70368.1 - 0.0097 16.0 0.0 0.042 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AJW70368.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AJW70368.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 AJW70368.1 - 0.016 14.4 0.4 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AJW70368.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 AJW70368.1 - 0.028 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 AJW70368.1 - 0.031 14.7 0.0 0.077 13.4 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein Rad17 PF03215.10 AJW70368.1 - 0.041 12.5 0.1 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 AJW70368.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AJW70368.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 AJW70368.1 - 0.074 12.7 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 AJW70368.1 - 0.11 11.9 0.2 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein UPF0079 PF02367.12 AJW70368.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 BPD_transp_1 PF00528.17 AJW70369.1 - 2.8e-21 75.8 16.7 5.3e-21 74.9 11.6 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Cu-oxidase_2 PF07731.9 AJW70371.1 - 1.9e-08 33.8 8.0 1.9e-07 30.6 4.3 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 AJW70371.1 - 0.11 12.2 6.1 0.025 14.2 0.7 2.4 2 0 0 2 2 2 0 Multicopper oxidase MFS_1 PF07690.11 AJW70372.1 - 3.2e-27 95.1 44.8 7.2e-25 87.4 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4094 PF13334.1 AJW70372.1 - 0.028 14.8 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) MTHFR PF02219.12 AJW70373.1 - 0.002 17.2 0.0 0.0025 16.9 0.0 1.3 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase NUDIX PF00293.23 AJW70374.1 - 6.9e-11 41.9 0.0 9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L39 PF00832.15 AJW70375.1 - 4e-19 67.8 6.9 4.6e-19 67.6 4.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.13 AJW70375.1 - 0.26 11.2 2.3 0.27 11.1 1.6 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ribosomal_L31e PF01198.14 AJW70376.1 - 2.6e-23 81.4 0.5 3.5e-23 81.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Tubulin PF00091.20 AJW70377.1 - 2.4e-13 50.4 0.2 2e-12 47.3 0.0 2.0 1 1 1 2 2 2 1 Tubulin/FtsZ family, GTPase domain TrkA_N PF02254.13 AJW70377.1 - 0.098 12.6 0.1 0.29 11.1 0.0 1.9 2 1 1 3 3 3 0 TrkA-N domain Radical_SAM PF04055.16 AJW70378.1 - 1.7e-19 70.5 0.1 2.5e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 AJW70378.1 - 1.8e-15 56.5 0.7 3.8e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Lyase_1 PF00206.15 AJW70379.1 - 1.3e-86 290.5 2.0 1.9e-86 290.1 1.4 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 AJW70379.1 - 8.6e-13 48.1 0.0 2.3e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Cu-oxidase_3 PF07732.10 AJW70380.1 - 1e-07 31.6 0.7 6.9e-07 29.0 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AJW70380.1 - 0.0014 18.0 0.9 0.26 10.7 0.2 2.5 2 0 0 2 2 2 2 Multicopper oxidase 2-Hacid_dh_C PF02826.14 AJW70381.1 - 4.1e-62 208.4 0.1 7.7e-62 207.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AJW70381.1 - 5.8e-29 100.2 0.3 6.7e-29 100.0 0.2 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AJW70381.1 - 0.00033 20.5 0.8 0.0009 19.1 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase LXG PF04740.7 AJW70381.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF3436 PF11918.3 AJW70381.1 - 0.069 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) Trypan_PARP PF05887.6 AJW70382.1 - 2.8 7.7 17.8 5 6.9 12.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 AJW70382.1 - 4.2 5.6 7.6 6 5.1 5.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Ribosomal_L15e PF00827.12 AJW70385.1 - 3.4e-46 157.1 2.2 3.9e-46 156.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L5_C PF00673.16 AJW70386.1 - 0.12 12.1 0.8 0.43 10.3 0.1 2.0 2 0 0 2 2 2 0 ribosomal L5P family C-terminus DUF2304 PF10066.4 AJW70386.1 - 0.23 11.3 1.3 5 7.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) AhpC-TSA PF00578.16 AJW70388.1 - 6.4e-09 35.5 0.5 3.4e-07 29.9 0.3 2.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJW70388.1 - 2.1e-07 30.6 0.1 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin_8 PF13905.1 AJW70388.1 - 0.0016 18.4 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AJW70388.1 - 0.002 18.3 0.6 0.028 14.6 0.4 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Response_reg PF00072.19 AJW70389.1 - 7e-24 83.9 0.1 8.2e-24 83.7 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HEAT_2 PF13646.1 AJW70390.1 - 5.5e-28 97.0 0.1 5.7e-20 71.4 0.1 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 AJW70390.1 - 1.4e-15 55.8 0.1 0.015 15.3 0.0 4.2 4 0 0 4 4 4 4 HEAT repeat HEAT_PBS PF03130.11 AJW70390.1 - 3.4e-13 48.6 0.0 7e-05 22.9 0.1 3.5 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 AJW70390.1 - 5e-13 49.1 0.0 0.006 17.0 0.0 3.9 4 0 0 4 4 4 3 HEAT-like repeat Adaptin_N PF01602.15 AJW70390.1 - 0.00018 20.0 0.0 0.00039 18.8 0.0 1.5 1 1 1 2 2 2 1 Adaptin N terminal region Arm PF00514.18 AJW70390.1 - 0.00026 20.6 0.0 0.54 10.1 0.0 3.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat ERAP1_C PF11838.3 AJW70390.1 - 0.027 13.7 0.0 0.061 12.5 0.0 1.6 1 1 0 1 1 1 0 ERAP1-like C-terminal domain Cnd1 PF12717.2 AJW70390.1 - 0.034 14.0 0.1 13 5.6 0.0 3.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Copper-bind PF00127.15 AJW70391.1 - 4.6e-18 65.2 2.4 6.9e-08 32.6 0.3 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW70391.1 - 1.1e-12 47.6 0.0 5.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain Kazal_1 PF00050.16 AJW70391.1 - 2.1e-10 40.4 0.5 6.7e-10 38.8 0.3 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 AJW70391.1 - 9.4e-10 38.2 0.9 2.1e-09 37.1 0.6 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Trypan_PARP PF05887.6 AJW70391.1 - 0.0012 18.7 21.6 0.0053 16.5 8.6 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) PKD PF00801.15 AJW70391.1 - 5.4 6.8 13.7 0.63 9.8 3.6 3.0 2 2 0 2 2 2 0 PKD domain FumaraseC_C PF10415.4 AJW70391.1 - 6.7 6.8 5.8 30 4.7 0.2 3.0 3 0 0 3 3 3 0 Fumarase C C-terminus SMC_N PF02463.14 AJW70392.1 - 2.7e-15 56.1 26.7 3.2e-09 36.3 0.9 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AJW70392.1 - 4.4e-14 53.2 42.8 4.4e-14 53.2 29.6 4.1 1 1 1 2 2 1 1 AAA domain AAA_29 PF13555.1 AJW70392.1 - 5.2e-09 35.4 0.2 1.1e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 AJW70392.1 - 1.1e-08 35.3 30.4 1.4e-05 25.2 0.5 3.8 1 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 AJW70392.1 - 1.5e-08 34.3 0.1 3.2e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 AJW70392.1 - 2.1e-05 23.7 64.3 0.049 12.6 15.6 2.7 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 AJW70392.1 - 0.0019 18.5 28.4 0.0076 16.5 0.1 5.4 2 1 0 2 2 1 1 ABC transporter DUF258 PF03193.11 AJW70392.1 - 0.0092 15.1 0.1 0.0092 15.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DNA_ligase_ZBD PF03119.11 AJW70392.1 - 0.044 13.4 0.6 0.097 12.3 0.4 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Reo_sigmaC PF04582.7 AJW70392.1 - 0.057 12.5 4.5 1 8.5 0.2 2.8 2 2 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AJW70392.1 - 0.075 11.4 67.5 0.065 11.6 15.8 4.5 1 1 3 4 4 4 0 AAA domain M_domain PF12938.2 AJW70392.1 - 1.4 8.6 8.4 0.59 9.8 0.2 2.9 3 0 0 3 3 3 0 M domain of GW182 Spc7 PF08317.6 AJW70392.1 - 5.3 5.6 58.0 2.2 6.8 8.3 4.1 1 1 2 4 4 3 0 Spc7 kinetochore protein NPV_P10 PF05531.7 AJW70392.1 - 9 6.6 21.4 0.8 10.0 0.4 5.0 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Metallophos_2 PF12850.2 AJW70393.1 - 4.3e-11 42.8 0.2 6.5e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AJW70393.1 - 3e-08 33.3 2.8 5.5e-08 32.4 1.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1798 PF08807.5 AJW70393.1 - 0.027 14.1 0.2 0.091 12.4 0.2 1.9 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF87 PF01935.12 AJW70394.1 - 5.9e-37 127.6 3.4 5.9e-37 127.6 2.4 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 AJW70394.1 - 2.2e-14 53.6 6.1 3.7e-10 39.7 1.5 2.1 1 1 0 2 2 2 2 AAA-like domain DUF853 PF05872.7 AJW70394.1 - 7e-05 21.3 0.1 0.025 12.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) HAS-barrel PF09378.5 AJW70394.1 - 0.00019 21.2 0.2 0.00052 19.8 0.2 1.9 1 1 0 1 1 1 1 HAS barrel domain TrwB_AAD_bind PF10412.4 AJW70394.1 - 0.0018 17.0 0.1 0.0045 15.6 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 AJW70394.1 - 0.074 13.3 1.4 0.17 12.1 1.0 1.7 1 1 0 1 1 1 0 ABC transporter NurA PF09376.5 AJW70395.1 - 4.2e-18 65.7 0.1 6.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 NurA domain OpuAC PF04069.7 AJW70395.1 - 0.04 13.2 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system DUF108 PF01958.13 AJW70398.1 - 3.9e-33 113.5 0.2 8.3e-33 112.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.11 AJW70398.1 - 1.5e-14 54.3 0.0 2.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 AJW70398.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AJW70398.1 - 0.0041 17.5 0.4 0.0095 16.3 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AJW70398.1 - 0.005 16.6 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 AJW70398.1 - 0.042 14.3 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 AJW70398.1 - 0.087 12.4 0.1 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NadA PF02445.11 AJW70399.1 - 3.5e-116 387.1 3.8 3.9e-116 386.9 2.7 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein TPR_1 PF00515.23 AJW70400.1 - 9.5e-14 50.3 1.7 4.3e-06 26.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 AJW70400.1 - 1.1e-12 47.3 0.4 5.4e-12 45.1 0.1 1.9 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 AJW70400.1 - 2.3e-11 42.6 0.2 2.6e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AJW70400.1 - 3.2e-11 42.9 0.8 3.2e-06 26.9 0.1 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AJW70400.1 - 3.1e-09 37.2 0.0 0.00032 21.2 0.0 2.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AJW70400.1 - 1.6e-08 34.7 0.0 9e-07 29.1 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AJW70400.1 - 1.6e-07 31.3 1.4 3.5e-07 30.2 0.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AJW70400.1 - 1.3e-06 27.7 1.9 0.013 15.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AJW70400.1 - 1.5e-06 27.5 0.1 0.012 15.3 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJW70400.1 - 1e-05 25.3 0.2 0.96 9.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJW70400.1 - 1.5e-05 24.7 2.2 0.0065 16.3 0.2 3.1 1 1 2 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AJW70400.1 - 0.0004 20.6 0.0 0.82 10.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJW70400.1 - 0.00069 20.0 0.0 0.28 11.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Tcf25 PF04910.9 AJW70400.1 - 0.0021 17.1 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_9 PF13371.1 AJW70400.1 - 0.0064 16.3 0.0 0.093 12.5 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat P4Ha_N PF08336.6 AJW70400.1 - 0.011 15.5 0.1 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NARP1 PF12569.3 AJW70400.1 - 0.017 13.9 0.6 0.021 13.6 0.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Prefoldin PF02996.12 AJW70400.1 - 0.019 14.5 2.7 0.036 13.7 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit Cas_Cas02710 PF09670.5 AJW70400.1 - 0.039 12.5 0.2 0.046 12.3 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) PARP_reg PF02877.9 AJW70400.1 - 0.057 13.0 0.5 0.12 12.0 0.1 1.7 1 1 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Pec_lyase PF09492.5 AJW70400.1 - 0.12 11.5 0.1 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Pectic acid lyase QRPTase_C PF01729.14 AJW70401.1 - 9.2e-56 187.9 1.7 1.2e-55 187.5 1.2 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 AJW70401.1 - 8.9e-28 95.9 0.0 1.8e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 AJW70401.1 - 0.00047 19.3 0.1 0.00096 18.3 0.1 1.5 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 AJW70401.1 - 0.0074 15.4 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Spt4 PF06093.8 AJW70402.1 - 6.9e-13 48.2 0.3 8.8e-13 47.9 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Laminin_EGF PF00053.19 AJW70402.1 - 0.07 13.0 0.8 0.094 12.6 0.6 1.2 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) RecR PF02132.10 AJW70402.1 - 0.085 12.2 0.7 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 RecR protein zf-RING_4 PF14570.1 AJW70402.1 - 0.21 11.1 2.2 0.33 10.5 1.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SHS2_Rpb7-N PF03876.12 AJW70403.1 - 5.4e-17 61.6 0.0 1.4e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AJW70403.1 - 2.7e-14 52.9 0.0 4.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.1 AJW70403.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 S1 domain BPL_C PF02237.12 AJW70403.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain ParA PF10609.4 AJW70404.1 - 8.7e-37 124.8 0.3 5.6e-36 122.2 0.3 2.1 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 AJW70404.1 - 2.6e-20 72.6 0.1 3.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 AJW70404.1 - 7.5e-18 64.2 2.0 2.5e-17 62.5 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF59 AAA_31 PF13614.1 AJW70404.1 - 2.9e-11 43.5 0.1 9.1e-11 41.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 AJW70404.1 - 6.4e-08 31.9 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 AJW70404.1 - 1.2e-06 27.9 0.0 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 AJW70404.1 - 2.2e-06 27.4 0.7 0.0093 15.5 0.0 2.5 3 0 0 3 3 3 2 AAA domain ArsA_ATPase PF02374.10 AJW70404.1 - 1.5e-05 24.2 2.1 1.9e-05 23.8 0.5 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.6 AJW70404.1 - 0.0031 16.6 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein ArgK PF03308.11 AJW70404.1 - 0.011 14.4 0.5 0.018 13.8 0.3 1.2 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 AJW70404.1 - 0.04 13.3 0.3 0.082 12.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AJW70404.1 - 0.13 11.9 0.1 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF359 PF04019.7 AJW70405.1 - 3.4e-35 120.0 0.0 4.2e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF359) DUF45 PF01863.12 AJW70406.1 - 0.0019 18.0 0.1 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 AJW70406.1 - 0.0034 17.0 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_M76 PF09768.4 AJW70406.1 - 0.081 12.3 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M76 family WLM PF08325.5 AJW70406.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 WLM domain H_PPase PF03030.11 AJW70407.1 - 4e-226 752.4 53.8 4.7e-226 752.2 37.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF3481 PF11980.3 AJW70407.1 - 0.092 12.5 2.0 0.92 9.3 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Adeno_E3_CR1 PF02440.10 AJW70408.1 - 0.1 12.0 1.5 0.13 11.7 1.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 UPF0262 PF06793.7 AJW70408.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) zf-CDGSH PF09360.5 AJW70408.1 - 0.94 9.3 3.2 1.9 8.3 2.2 1.5 1 1 0 1 1 1 0 Iron-binding zinc finger CDGSH type DUF2024 PF09630.5 AJW70409.1 - 1.7e-38 130.1 1.0 1.9e-38 130.0 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) CCG PF02754.11 AJW70409.1 - 0.081 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich domain Cyclophil_like PF04126.8 AJW70410.1 - 1.3e-39 134.4 0.0 1.5e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like DUF3830 PF12903.2 AJW70410.1 - 0.089 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) Prok-JAB PF14464.1 AJW70411.1 - 3.3e-17 61.9 0.0 4.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 AJW70411.1 - 6.6e-07 29.0 0.0 9.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Toxin-JAB1 PF15659.1 AJW70411.1 - 0.04 13.7 0.1 0.087 12.7 0.0 1.6 2 0 0 2 2 2 0 JAB-like toxin 1 DUF3447 PF11929.3 AJW70411.1 - 0.076 12.8 0.9 0.14 11.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Copper-bind PF00127.15 AJW70412.1 - 5.5e-14 52.1 0.1 1e-07 32.1 0.0 2.8 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW70412.1 - 1.4e-11 44.1 0.0 0.00019 21.2 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain UbiA PF01040.13 AJW70413.1 - 1.7e-27 96.3 22.1 2.1e-27 95.9 15.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family AAA PF00004.24 AJW70415.1 - 6.5e-89 294.9 0.0 4.4e-48 162.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AJW70415.1 - 3e-24 84.7 0.3 1.1e-23 82.9 0.2 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AJW70415.1 - 4.7e-15 55.2 0.1 7e-09 35.0 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AJW70415.1 - 2e-12 47.1 0.0 3.4e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AJW70415.1 - 4.6e-12 46.2 0.3 0.0018 18.3 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AJW70415.1 - 6.7e-12 45.7 0.0 0.0001 22.3 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 AJW70415.1 - 8.7e-12 45.2 0.0 8.1e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 AJW70415.1 - 7.3e-11 42.9 0.3 0.00025 21.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 AJW70415.1 - 1.3e-10 40.7 0.6 4e-10 39.1 0.2 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 Arch_ATPase PF01637.13 AJW70415.1 - 2.3e-10 40.6 0.1 0.00019 21.2 0.0 3.9 2 1 1 3 3 3 2 Archaeal ATPase AAA_5 PF07728.9 AJW70415.1 - 2.8e-10 40.0 0.7 8.6e-05 22.2 0.0 4.3 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AJW70415.1 - 8.6e-10 38.6 0.0 0.00045 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AJW70415.1 - 3.2e-08 33.6 0.0 0.0037 17.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 AJW70415.1 - 4.1e-08 32.8 4.2 0.31 10.4 0.1 4.3 2 2 0 4 4 4 3 AAA domain AAA_18 PF13238.1 AJW70415.1 - 1.4e-07 31.8 0.1 0.034 14.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 AJW70415.1 - 4e-07 30.4 0.0 0.014 15.7 0.0 2.9 2 1 0 3 3 2 2 ABC transporter IstB_IS21 PF01695.12 AJW70415.1 - 5.6e-07 29.1 0.0 0.03 13.7 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 AJW70415.1 - 9.4e-07 28.9 0.0 0.052 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AJW70415.1 - 9.5e-07 28.1 0.2 0.0048 16.0 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin KaiC PF06745.8 AJW70415.1 - 4.2e-06 26.0 1.1 0.12 11.4 0.0 3.7 3 1 1 4 4 4 2 KaiC Sigma54_activ_2 PF14532.1 AJW70415.1 - 6.1e-06 26.3 0.0 0.027 14.5 0.0 3.2 2 1 1 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 AJW70415.1 - 8.2e-06 25.1 1.0 0.015 14.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AJW70415.1 - 1.2e-05 25.0 0.4 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 AJW70415.1 - 2.1e-05 24.2 0.4 0.42 10.2 0.0 3.9 4 0 0 4 4 4 1 NACHT domain TIP49 PF06068.8 AJW70415.1 - 3.4e-05 22.7 0.1 0.12 11.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 AJW70415.1 - 0.00017 21.2 1.0 0.17 11.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 AJW70415.1 - 0.00037 19.3 0.0 0.43 9.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 AJW70415.1 - 0.00073 19.1 0.0 0.25 10.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 AJW70415.1 - 0.0008 18.9 0.0 0.68 9.3 0.0 3.6 3 1 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.11 AJW70415.1 - 0.00092 18.4 0.4 0.69 9.1 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein ATP-synt_ab PF00006.20 AJW70415.1 - 0.001 18.5 0.0 2.7 7.4 0.0 3.0 2 1 1 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 AJW70415.1 - 0.0013 17.8 0.0 1.2 8.0 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 AJW70415.1 - 0.0013 17.7 0.0 2.9 6.7 0.0 3.1 2 1 1 3 3 3 1 KAP family P-loop domain SKI PF01202.17 AJW70415.1 - 0.0014 18.4 0.1 0.81 9.5 0.0 3.0 3 0 0 3 3 3 1 Shikimate kinase SRPRB PF09439.5 AJW70415.1 - 0.0058 15.8 0.0 3.4 6.8 0.0 3.4 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit AAA_3 PF07726.6 AJW70415.1 - 0.0064 16.1 0.1 3.1 7.3 0.0 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 AJW70415.1 - 0.008 15.1 0.0 3.5 6.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF815) ResIII PF04851.10 AJW70415.1 - 0.012 15.4 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 AJW70415.1 - 0.013 14.9 0.6 13 5.0 0.0 3.8 2 2 2 4 4 4 0 AAA-like domain AAA_11 PF13086.1 AJW70415.1 - 0.014 14.9 0.0 2.7 7.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AJW70415.1 - 0.022 14.3 0.1 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DAP3 PF10236.4 AJW70415.1 - 0.029 13.2 0.1 1.9 7.3 0.0 2.6 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_21 PF13304.1 AJW70415.1 - 0.033 14.1 0.4 12 5.7 0.0 3.4 2 1 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 AJW70415.1 - 0.063 13.1 0.0 9.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family SPOUT_MTase PF02590.12 AJW70415.1 - 0.073 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Parvo_NS1 PF01057.12 AJW70415.1 - 0.076 11.8 0.1 3.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 AJW70415.1 - 0.16 10.8 1.3 3.1 6.5 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain EF1_GNE PF00736.14 AJW70416.1 - 7.7e-22 76.7 0.2 8.4e-22 76.6 0.1 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain FAD_binding_3 PF01494.14 AJW70417.1 - 1.1e-08 34.6 0.8 0.0031 16.6 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 AJW70417.1 - 3.6e-07 29.4 0.0 1.3e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 AJW70417.1 - 8.9e-06 25.0 0.1 7.7e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AJW70417.1 - 9.2e-06 24.3 0.9 0.00096 17.7 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 AJW70417.1 - 1.6e-05 24.8 0.0 0.00014 21.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AJW70417.1 - 6.7e-05 21.9 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 AJW70417.1 - 9.2e-05 21.6 0.7 9.2e-05 21.6 0.5 2.0 2 1 0 2 2 2 1 Thi4 family DAO PF01266.19 AJW70417.1 - 0.00024 20.1 3.2 0.0064 15.4 0.9 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AJW70417.1 - 0.00026 20.9 0.4 0.002 18.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Myosin_N PF02736.14 AJW70417.1 - 0.047 13.3 0.4 0.78 9.4 0.0 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Amino_oxidase PF01593.19 AJW70417.1 - 0.11 11.4 0.1 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 AJW70417.1 - 7.8 6.9 6.8 17 5.9 0.7 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PTH2 PF01981.11 AJW70418.1 - 1.2e-43 147.4 0.2 1.3e-43 147.3 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SGL PF08450.7 AJW70419.1 - 7.7e-06 25.4 2.5 0.9 8.8 0.0 4.3 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 AJW70419.1 - 0.017 15.0 2.1 11 6.2 0.0 4.3 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.6 AJW70419.1 - 0.049 13.6 10.9 6.1 7.2 0.2 5.1 6 0 0 6 6 6 0 Two component regulator propeller OLF PF02191.11 AJW70419.1 - 0.095 11.9 0.0 9.2 5.4 0.0 3.1 3 0 0 3 3 3 0 Olfactomedin-like domain AsnC_trans_reg PF01037.16 AJW70420.1 - 8.3e-11 41.4 0.0 8.7e-11 41.3 0.0 1.0 1 0 0 1 1 1 1 AsnC family DUF2530 PF10745.4 AJW70421.1 - 0.0053 16.7 3.6 1.1 9.3 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2530) EII-Sor PF03609.9 AJW70421.1 - 0.021 14.0 1.9 0.022 14.0 1.3 1.0 1 0 0 1 1 1 0 PTS system sorbose-specific iic component ABC2_membrane_4 PF12730.2 AJW70421.1 - 0.028 13.5 3.9 0.029 13.5 2.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein FtsX PF02687.16 AJW70421.1 - 0.038 13.7 7.2 0.044 13.5 5.0 1.1 1 0 0 1 1 1 0 FtsX-like permease family DUF2157 PF09925.4 AJW70421.1 - 0.24 10.9 1.7 4.8 6.7 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) ABC2_membrane_5 PF13346.1 AJW70421.1 - 1 8.6 7.1 1.1 8.4 4.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF973 PF06157.6 AJW70421.1 - 1.8 7.4 9.6 2.3 7.1 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Tetraspannin PF00335.15 AJW70421.1 - 2.1 7.5 5.8 2.6 7.2 4.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF1469 PF07332.6 AJW70421.1 - 2.6 7.8 6.4 0.53 10.0 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) DUF2177 PF09945.4 AJW70422.1 - 0.066 13.2 5.0 1.9 8.5 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) DUF1129 PF06570.6 AJW70422.1 - 2 7.6 10.6 0.72 9.1 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) zf-CHY PF05495.7 AJW70424.1 - 0.067 13.3 3.2 0.13 12.4 2.3 1.5 1 0 0 1 1 1 0 CHY zinc finger OrfB_Zn_ribbon PF07282.6 AJW70424.1 - 0.097 12.3 2.8 0.2 11.3 2.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Desulfoferrod_N PF06397.7 AJW70424.1 - 0.14 11.5 5.4 0.8 9.1 0.1 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain HypA PF01155.14 AJW70424.1 - 0.52 10.0 3.3 0.75 9.5 2.3 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 AJW70424.1 - 0.54 10.1 6.0 0.23 11.2 1.6 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cas_GSU0053 PF09617.5 AJW70425.1 - 0.074 12.8 0.1 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) zf-CHY PF05495.7 AJW70426.1 - 0.28 11.3 6.0 0.35 11.0 4.2 1.2 1 1 0 1 1 1 0 CHY zinc finger ADH_N PF08240.7 AJW70427.1 - 4.9e-29 100.2 0.5 8.9e-29 99.4 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJW70427.1 - 9.7e-15 54.2 0.4 1.6e-14 53.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AJW70427.1 - 0.00046 19.3 0.0 0.00096 18.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.14 AJW70427.1 - 0.019 15.4 5.9 0.088 13.3 2.4 3.0 2 1 1 3 3 3 0 CoA binding domain GFO_IDH_MocA PF01408.17 AJW70427.1 - 0.034 14.6 0.8 0.31 11.5 0.1 2.2 1 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N_2 PF13602.1 AJW70427.1 - 0.044 14.6 0.0 0.081 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 AJW70427.1 - 0.075 12.8 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_18 PF12847.2 AJW70427.1 - 0.12 12.9 0.1 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 AJW70427.1 - 0.12 11.9 1.4 0.37 10.3 0.9 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trns_repr_metal PF02583.12 AJW70428.1 - 0.069 13.3 0.3 0.087 13.0 0.2 1.2 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor DUF2951 PF11166.3 AJW70428.1 - 0.093 12.5 3.2 0.12 12.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF2265 PF10023.4 AJW70428.1 - 0.19 10.8 1.5 0.21 10.7 1.0 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Thioredox_DsbH PF03190.10 AJW70429.1 - 2.2e-76 255.1 0.1 3.6e-76 254.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 AJW70429.1 - 5.1e-14 52.0 0.0 1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 AJW70429.1 - 1.6e-07 30.8 1.7 0.032 13.5 0.1 3.8 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Thioredoxin_2 PF13098.1 AJW70429.1 - 7.6e-05 22.8 0.0 0.00025 21.2 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_88 PF07470.8 AJW70429.1 - 0.00018 20.6 0.2 0.12 11.3 0.0 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 LANC_like PF05147.8 AJW70429.1 - 0.00048 18.8 2.9 4.6 5.7 0.0 4.9 4 1 0 5 5 5 2 Lanthionine synthetase C-like protein GlcNAc_2-epim PF07221.6 AJW70429.1 - 0.0017 17.4 0.0 2.1 7.2 0.0 2.8 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1680 PF07944.7 AJW70429.1 - 0.0049 15.2 0.1 0.17 10.1 0.0 2.7 2 1 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 AJW70429.1 - 0.0052 16.2 0.1 0.23 10.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Pec_lyase PF09492.5 AJW70429.1 - 0.019 14.1 0.1 0.58 9.2 0.0 2.3 2 0 0 2 2 2 0 Pectic acid lyase Integrase_Zn PF02022.14 AJW70429.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain DUF816 PF05674.7 AJW70430.1 - 0.084 12.5 1.2 4.1 7.0 0.1 2.2 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF816) Activator-TraM PF11657.3 AJW70430.1 - 0.1 12.1 0.7 4.1 6.8 0.1 2.1 1 1 1 2 2 2 0 Transcriptional activator TraM DUF771 PF05595.6 AJW70431.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF771) Glycoprotein_G PF00802.14 AJW70432.1 - 0.049 12.7 0.8 0.05 12.7 0.5 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DASH_Duo1 PF08651.5 AJW70433.1 - 0.00035 20.0 0.4 0.00069 19.1 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 Chalcone PF02431.10 AJW70433.1 - 0.045 13.1 0.1 0.053 12.9 0.1 1.1 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Laminin_II PF06009.7 AJW70433.1 - 0.062 13.0 1.2 0.089 12.5 0.8 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF1732 PF08340.6 AJW70433.1 - 0.1 12.4 0.2 0.21 11.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Fusion_gly PF00523.13 AJW70433.1 - 0.12 10.4 0.1 0.14 10.1 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 UvsY PF11056.3 AJW70433.1 - 0.13 12.3 0.5 0.26 11.4 0.3 1.5 1 1 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF3426 PF11906.3 AJW70434.1 - 1e-06 28.4 0.1 0.0031 17.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3426) DUF2393 PF09624.5 AJW70434.1 - 0.0027 17.2 0.5 0.0027 17.2 0.3 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2393) 60KD_IMP PF02096.15 AJW70437.1 - 0.00028 20.6 0.3 0.00044 19.9 0.2 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3139 PF11337.3 AJW70437.1 - 0.0023 18.1 1.6 0.0055 16.9 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) Bac_small_YrzI PF09501.5 AJW70437.1 - 0.038 13.9 0.7 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Vpu PF00558.14 AJW70437.1 - 0.042 13.3 0.5 0.087 12.3 0.4 1.6 1 0 0 1 1 1 0 Vpu protein Vps5 PF09325.5 AJW70437.1 - 0.081 12.1 6.6 0.024 13.8 1.7 1.9 2 0 0 2 2 2 0 Vps5 C terminal like DUF4429 PF14472.1 AJW70437.1 - 0.15 12.4 0.4 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4429) Streptin-Immun PF11083.3 AJW70437.1 - 0.76 9.8 5.6 1.4 8.9 1.0 2.5 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein AsnC_trans_reg PF01037.16 AJW70439.1 - 3e-08 33.2 0.1 3e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AJW70439.1 - 0.00035 20.2 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 GYD domain Tet_JBP PF12851.2 AJW70439.1 - 0.025 13.8 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DEAD PF00270.24 AJW70440.1 - 1e-47 161.7 0.1 3e-45 153.7 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AJW70440.1 - 1e-26 92.5 0.0 2.2e-25 88.2 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 AJW70440.1 - 0.0017 17.9 0.1 0.0053 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 AJW70440.1 - 0.0029 16.4 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 AJW70440.1 - 0.0032 17.4 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain CMS1 PF14617.1 AJW70440.1 - 0.0056 15.7 0.3 0.026 13.5 0.0 2.1 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 AJW70440.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit His_Phos_1 PF00300.17 AJW70440.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Thioredoxin_4 PF13462.1 AJW70441.1 - 2.3e-41 141.5 0.0 3.9e-41 140.7 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.15 AJW70441.1 - 3.3e-17 62.6 0.1 3.1e-09 36.6 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJW70441.1 - 2.5e-08 34.0 0.0 5.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 AJW70441.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin NfeD PF01957.13 AJW70442.1 - 0.041 14.0 0.3 0.044 13.9 0.2 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding MerC PF03203.9 AJW70442.1 - 0.15 12.4 1.1 0.17 12.2 0.8 1.0 1 0 0 1 1 1 0 MerC mercury resistance protein PvlArgDC PF01862.11 AJW70443.1 - 1.5e-61 206.7 0.0 1.7e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF3753 PF12575.3 AJW70444.1 - 0.7 9.7 4.5 2.8 7.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) DUF4149 PF13664.1 AJW70445.1 - 4.6 7.3 15.9 3.8 7.6 5.9 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4149) Peptidase_M3 PF01432.15 AJW70446.1 - 2.9e-44 151.8 0.5 9e-44 150.2 0.3 1.8 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.5 AJW70446.1 - 9e-08 32.0 3.3 1.5e-07 31.3 0.1 3.0 3 0 0 3 3 3 1 Oligopeptidase F DUF955 PF06114.8 AJW70446.1 - 0.003 17.2 0.0 0.0079 15.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF955) Peptidase_MA_2 PF13485.1 AJW70446.1 - 0.01 15.8 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily NPV_P10 PF05531.7 AJW70446.1 - 0.032 14.4 2.0 0.15 12.3 0.2 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Zn_peptidase_2 PF04298.7 AJW70446.1 - 0.13 11.5 0.1 0.29 10.4 0.1 1.5 1 1 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF2762 PF10960.3 AJW70446.1 - 1.4 8.6 5.5 19 5.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) CoaE PF01121.15 AJW70447.1 - 0.025 13.9 0.1 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase zf-UBP PF02148.14 AJW70448.1 - 9.1e-12 44.9 8.1 1.7e-11 44.0 5.6 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein FYVE PF01363.16 AJW70448.1 - 0.8 9.6 7.1 0.96 9.3 4.9 1.3 1 0 0 1 1 1 0 FYVE zinc finger UPF0547 PF10571.4 AJW70448.1 - 2.6 7.8 9.4 0.92 9.2 3.1 2.5 2 1 1 3 3 3 0 Uncharacterised protein family UPF0547 zf-RING_UBOX PF13445.1 AJW70448.1 - 3.2 7.5 7.9 7.2 6.4 5.4 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C2HC5 PF06221.8 AJW70448.1 - 7.4 6.4 12.7 18 5.1 6.6 2.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Pyrophosphatase PF00719.14 AJW70449.1 - 3e-58 195.7 0.3 3.4e-58 195.5 0.2 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase FMN_red PF03358.10 AJW70450.1 - 9.4e-36 122.6 0.0 1.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AJW70450.1 - 7.2e-11 41.9 0.0 9.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold CoA_binding_2 PF13380.1 AJW70450.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain UPF0506 PF11703.3 AJW70452.1 - 0.053 13.4 1.1 0.083 12.8 0.7 1.5 1 1 0 1 1 1 0 UPF0506 DUF406 PF04175.7 AJW70452.1 - 0.14 12.6 0.2 0.15 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF406) C1_1 PF00130.17 AJW70452.1 - 0.19 11.4 1.4 0.71 9.6 1.0 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YhfH PF14149.1 AJW70452.1 - 1.4 8.7 4.1 0.39 10.5 0.8 1.7 2 1 0 2 2 2 0 YhfH-like protein Nab2 PF11517.3 AJW70453.1 - 0.07 13.2 1.1 0.23 11.5 0.1 1.9 1 1 1 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Response_reg PF00072.19 AJW70454.1 - 1.5e-19 70.0 0.1 1.7e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 AJW70454.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain A2M_N PF01835.14 AJW70456.1 - 3.7e-09 36.7 0.1 0.002 18.3 0.0 2.2 2 0 0 2 2 2 2 MG2 domain DUF3244 PF11589.3 AJW70456.1 - 0.064 12.9 8.1 0.073 12.7 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3244) TPR_14 PF13428.1 AJW70457.1 - 0.1 13.3 0.2 0.2 12.3 0.2 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat V-SNARE PF05008.10 AJW70457.1 - 0.5 10.5 2.4 15 5.8 0.1 2.4 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CoA_binding PF02629.14 AJW70458.1 - 6.2e-21 74.7 0.9 2e-20 73.0 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 AJW70458.1 - 3.5e-08 33.1 0.1 6.2e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.1 AJW70458.1 - 2.4e-05 24.4 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 AJW70458.1 - 0.00037 20.1 0.3 0.00065 19.3 0.0 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.17 AJW70458.1 - 0.0024 18.3 0.0 0.004 17.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ATP-grasp_2 PF08442.5 AJW70459.1 - 6.8e-46 156.2 2.0 1.2e-45 155.4 1.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 AJW70459.1 - 3e-15 56.1 1.2 4.9e-15 55.4 0.1 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 AJW70459.1 - 1.4e-13 50.6 0.3 4.5e-13 48.9 0.2 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJW70459.1 - 6.6e-06 25.5 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 AJW70459.1 - 5e-05 23.1 0.0 9e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AJW70459.1 - 0.016 14.5 0.2 0.041 13.2 0.1 1.6 1 1 0 1 1 1 0 ATP-grasp domain DUF362 PF04015.7 AJW70459.1 - 0.042 13.3 0.0 0.41 10.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF362) Motilin_ghrelin PF04644.7 AJW70459.1 - 0.11 12.3 0.5 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 Motilin/ghrelin TF_Zn_Ribbon PF08271.7 AJW70460.1 - 0.0039 16.4 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Ferritin PF00210.19 AJW70461.1 - 1.1e-18 67.3 0.1 1.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AJW70461.1 - 0.019 15.3 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 Rubrerythrin tRNA-synt_1 PF00133.17 AJW70462.1 - 1.8e-145 485.3 1.2 2.7e-145 484.7 0.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AJW70462.1 - 2.8e-30 105.1 1.2 6.5e-30 103.9 0.9 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AJW70462.1 - 3.1e-23 82.0 0.7 1e-08 34.2 0.0 4.4 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1f PF01921.13 AJW70462.1 - 4.2e-05 22.3 0.0 0.00011 21.0 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.14 AJW70462.1 - 6.2e-05 22.2 0.0 0.00073 18.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Zn-ribbon_8 PF09723.5 AJW70462.1 - 0.41 10.6 2.4 4.8 7.2 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain GARS_A PF01071.14 AJW70463.1 - 3.4e-79 264.9 0.2 4.4e-79 264.5 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 AJW70463.1 - 6.7e-34 116.3 0.1 1.9e-33 114.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 AJW70463.1 - 4.7e-30 103.5 0.0 9.4e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 AJW70463.1 - 2.6e-11 43.5 0.0 4.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AJW70463.1 - 1.2e-06 28.0 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AJW70463.1 - 1.6e-06 28.0 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AJW70463.1 - 4.1e-05 22.4 0.0 0.00052 18.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_2 PF08442.5 AJW70463.1 - 8.1e-05 22.0 0.1 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJW70463.1 - 0.0001 21.6 0.1 0.0002 20.7 0.1 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 AJW70463.1 - 0.00025 20.4 0.1 0.0004 19.8 0.1 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 AJW70463.1 - 0.0028 17.1 0.0 0.0073 15.7 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain 5-FTHF_cyc-lig PF01812.15 AJW70464.1 - 1.2e-39 136.0 0.0 1.4e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF3482 PF11981.3 AJW70464.1 - 0.08 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) THF_DHG_CYH_C PF02882.14 AJW70465.1 - 9.9e-61 203.5 0.7 1.4e-60 202.9 0.5 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AJW70465.1 - 3.1e-39 133.6 1.8 5.3e-39 132.8 0.6 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 AJW70465.1 - 0.0058 16.7 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 AJW70465.1 - 0.017 15.4 0.0 0.065 13.5 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1884 PF08967.5 AJW70465.1 - 0.055 13.5 0.7 0.27 11.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1884) ABM PF03992.11 AJW70466.1 - 3.1e-09 36.7 0.0 3.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cupin_2 PF07883.6 AJW70467.1 - 5.9e-11 41.7 0.1 1.1e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.3 AJW70467.1 - 1.8e-06 27.8 0.1 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.14 AJW70467.1 - 2.7e-05 23.8 0.0 3.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Pirin_C PF05726.8 AJW70467.1 - 0.0013 18.7 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Pirin C-terminal cupin domain ARD PF03079.9 AJW70467.1 - 0.07 13.0 0.9 0.1 12.5 0.6 1.6 1 1 0 1 1 1 0 ARD/ARD' family Formyl_trans_N PF00551.14 AJW70468.1 - 7.8e-45 152.6 0.0 8.8e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase RMMBL PF07521.7 AJW70469.1 - 0.0026 17.5 0.0 0.0072 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 AJW70469.1 - 0.013 15.0 0.7 0.86 9.1 0.6 2.7 2 1 0 2 2 2 0 Beta-lactamase superfamily domain DUF4147 PF13660.1 AJW70471.1 - 2.9e-72 242.6 0.0 4e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 AJW70471.1 - 1.7e-27 95.5 0.3 4.8e-27 94.1 0.2 1.8 1 0 0 1 1 1 1 MOFRL family Peptidase_C13 PF01650.13 AJW70471.1 - 0.077 12.2 0.0 0.21 10.8 0.0 1.5 1 1 0 1 1 1 0 Peptidase C13 family Fe-ADH PF00465.14 AJW70472.1 - 1.4e-50 171.9 0.0 3e-50 170.8 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 AJW70472.1 - 1.4e-17 63.8 0.0 1.9e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 AJW70472.1 - 2.7e-05 23.2 0.0 0.0033 16.3 0.0 2.1 2 0 0 2 2 2 2 3-dehydroquinate synthase Peripla_BP_6 PF13458.1 AJW70472.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 2 0 0 2 2 2 0 Periplasmic binding protein ABC_sub_bind PF04392.7 AJW70472.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein Bac_luciferase PF00296.15 AJW70473.1 - 7.9e-55 186.1 0.0 9.9e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1940 PF09155.5 AJW70474.1 - 0.0038 17.0 0.7 0.0041 16.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1940) Cep57_MT_bd PF06657.8 AJW70475.1 - 0.00046 20.0 4.3 0.00062 19.6 3.0 1.2 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 SNARE PF05739.14 AJW70475.1 - 0.0067 16.0 2.3 1.3 8.8 0.5 2.2 2 0 0 2 2 2 2 SNARE domain Glyco_hydro_26 PF02156.10 AJW70475.1 - 0.051 13.0 0.6 0.06 12.8 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Med28 PF11594.3 AJW70475.1 - 0.16 12.1 6.0 0.21 11.8 4.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 Allexi_40kDa PF05549.6 AJW70475.1 - 0.17 11.1 2.6 0.18 11.0 1.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2317 PF10079.4 AJW70475.1 - 0.2 10.2 5.9 0.22 10.1 4.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) HK97-gp10_like PF04883.7 AJW70475.1 - 0.33 11.9 5.9 0.63 11.0 4.1 1.5 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Borrelia_REV PF03978.8 AJW70475.1 - 0.5 10.0 12.5 0.64 9.7 8.7 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF4358 PF14270.1 AJW70475.1 - 0.65 9.8 6.9 0.8 9.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) Tho2 PF11262.3 AJW70475.1 - 0.9 8.5 11.3 1 8.3 7.9 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2935 PF11155.3 AJW70475.1 - 1.1 9.4 5.9 11 6.1 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) FlxA PF14282.1 AJW70475.1 - 1.2 9.0 14.9 2.3 8.1 10.3 1.5 1 1 0 1 1 1 0 FlxA-like protein TMPIT PF07851.8 AJW70475.1 - 3.2 6.7 8.8 3.4 6.6 6.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.8 AJW70475.1 - 5.1 7.4 7.7 6.4 7.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pyridox_ox_2 PF12900.2 AJW70476.1 - 7.8e-20 71.1 0.0 1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 AJW70476.1 - 5.6e-11 42.3 0.0 1e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1059 PF06348.6 AJW70477.1 - 1.9e-09 37.1 0.1 2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) UvrB PF12344.3 AJW70478.1 - 4.6e-21 74.0 4.5 4.6e-21 74.0 3.1 2.1 2 0 0 2 2 2 1 Ultra-violet resistance protein B Helicase_C PF00271.26 AJW70478.1 - 2.1e-15 56.3 0.6 8.2e-15 54.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UVR PF02151.14 AJW70478.1 - 4.5e-09 35.5 1.1 2.7e-08 33.0 0.8 2.5 1 0 0 1 1 1 1 UvrB/uvrC motif ResIII PF04851.10 AJW70478.1 - 1.3e-08 34.9 0.1 1.3e-08 34.9 0.1 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AJW70478.1 - 8e-08 31.9 0.3 6.8e-05 22.4 0.1 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 AJW70478.1 - 0.0007 19.3 0.1 0.045 13.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Met_synt_B12 PF02965.12 AJW70478.1 - 0.015 14.4 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain AAA_30 PF13604.1 AJW70478.1 - 0.044 13.3 0.1 0.38 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AJW70478.1 - 0.048 13.8 0.6 2.1 8.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain Tup_N PF08581.5 AJW70478.1 - 0.57 10.3 11.6 3.5 7.8 0.0 4.0 3 1 1 4 4 4 0 Tup N-terminal ABC_tran PF00005.22 AJW70479.1 - 1.8e-22 80.1 0.2 0.00022 21.5 0.0 4.6 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.14 AJW70479.1 - 5.8e-10 38.7 0.6 0.071 12.3 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AJW70479.1 - 2e-08 33.6 0.1 0.0047 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 AJW70479.1 - 1.6e-07 31.6 13.9 0.0037 17.2 0.1 5.1 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.1 AJW70479.1 - 5.2e-07 29.8 0.0 0.011 15.7 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 AJW70479.1 - 1.1e-06 28.6 0.1 0.052 13.4 0.0 3.6 3 1 1 4 4 4 2 AAA domain AAA_33 PF13671.1 AJW70479.1 - 3.2e-06 27.0 0.3 0.13 12.1 0.0 3.4 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 AJW70479.1 - 4.2e-06 26.0 0.3 0.057 12.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AJW70479.1 - 1.4e-05 25.2 1.9 0.29 11.2 0.0 4.0 5 0 0 5 5 5 2 AAA domain Arch_ATPase PF01637.13 AJW70479.1 - 1.6e-05 24.7 1.3 0.047 13.3 0.0 3.7 3 1 0 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 AJW70479.1 - 2.1e-05 23.9 0.0 0.068 12.5 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 AJW70479.1 - 2.3e-05 25.1 6.2 0.088 13.6 0.4 4.2 4 0 0 4 4 3 2 AAA domain NB-ARC PF00931.17 AJW70479.1 - 2.4e-05 23.3 0.1 0.71 8.6 0.0 3.7 4 0 0 4 4 4 1 NB-ARC domain AAA_18 PF13238.1 AJW70479.1 - 3.3e-05 24.1 0.0 0.35 11.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AJW70479.1 - 7.2e-05 23.2 0.2 7.2e-05 23.2 0.1 3.7 4 0 0 4 4 3 1 AAA domain APS_kinase PF01583.15 AJW70479.1 - 9.6e-05 22.0 0.1 0.28 10.8 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_10 PF12846.2 AJW70479.1 - 0.00013 21.5 0.1 0.43 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 AJW70479.1 - 0.00014 21.5 0.0 0.27 10.9 0.0 3.3 4 0 0 4 4 3 1 Part of AAA domain MobB PF03205.9 AJW70479.1 - 0.00038 20.1 0.4 0.25 11.0 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 AJW70479.1 - 0.00094 18.7 0.0 0.089 12.3 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 AJW70479.1 - 0.001 18.8 0.7 0.82 9.3 0.0 3.5 3 0 0 3 3 3 1 NTPase KaiC PF06745.8 AJW70479.1 - 0.0013 17.9 0.6 0.78 8.8 0.0 3.0 3 0 0 3 3 3 1 KaiC DUF2075 PF09848.4 AJW70479.1 - 0.0014 17.6 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 AJW70479.1 - 0.0018 17.1 0.0 0.35 9.6 0.0 2.6 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 AJW70479.1 - 0.0019 17.9 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain PRK PF00485.13 AJW70479.1 - 0.0021 17.6 0.0 0.22 11.0 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DnaJ_CXXCXGXG PF00684.14 AJW70479.1 - 0.0023 17.9 0.4 0.0023 17.9 0.3 4.4 4 1 1 5 5 4 1 DnaJ central domain MMR_HSR1 PF01926.18 AJW70479.1 - 0.0023 17.8 4.5 0.13 12.2 0.1 3.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase cobW PF02492.14 AJW70479.1 - 0.0024 17.3 0.4 0.68 9.3 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 AJW70479.1 - 0.0054 15.6 0.4 2 7.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 AJW70479.1 - 0.0067 15.9 0.2 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 AJW70479.1 - 0.013 15.6 0.2 3.4 7.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Miro PF08477.8 AJW70479.1 - 0.028 14.9 0.2 5.1 7.6 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 AJW70479.1 - 0.035 14.0 1.1 8.2 6.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AJW70479.1 - 0.078 12.5 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 AJW70479.1 - 0.088 11.2 0.0 11 4.4 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein ATP_bind_1 PF03029.12 AJW70479.1 - 0.14 11.6 0.5 4.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 AJW70479.1 - 0.15 11.1 0.0 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin zf-ribbon_3 PF13248.1 AJW70479.1 - 0.34 10.1 3.8 6.6 6.0 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJW70479.1 - 2.5 7.6 7.9 4.4 6.9 0.1 2.9 3 0 0 3 3 2 0 zinc-ribbon domain UvrC_HhH_N PF08459.6 AJW70480.1 - 1.1e-49 167.8 1.3 2.4e-49 166.8 0.0 2.3 3 0 0 3 3 3 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.19 AJW70480.1 - 4.5e-13 49.3 2.7 4.5e-13 49.3 1.9 2.6 3 0 0 3 3 3 1 GIY-YIG catalytic domain UVR PF02151.14 AJW70480.1 - 6.8e-09 34.9 0.4 2.2e-08 33.3 0.3 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif Copper-bind PF00127.15 AJW70481.1 - 1.2e-08 35.0 1.3 2.4e-08 34.1 0.0 2.1 2 2 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW70481.1 - 0.00073 19.4 0.0 0.0036 17.1 0.0 2.1 2 1 0 2 2 2 1 Cupredoxin-like domain Peptidase_S49_N PF08496.5 AJW70481.1 - 0.23 11.2 1.1 0.33 10.7 0.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PBP_sp32 PF07222.7 AJW70481.1 - 1.2 8.2 5.0 1.7 7.7 3.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Halo_GVPC PF05465.8 AJW70484.1 - 0.1 12.5 1.5 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF1799 PF08809.6 AJW70484.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) EndoU_bacteria PF14436.1 AJW70484.1 - 0.13 12.0 2.6 0.18 11.6 1.8 1.2 1 0 0 1 1 1 0 Bacterial EndoU nuclease OEP PF02321.13 AJW70484.1 - 1.1 8.7 4.8 2.8 7.5 3.4 1.6 1 1 0 1 1 1 0 Outer membrane efflux protein Pyr_redox_2 PF07992.9 AJW70485.1 - 8.8e-17 61.6 0.0 1.8e-16 60.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJW70485.1 - 9.4e-09 35.5 1.1 2.9e-06 27.6 0.7 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AJW70485.1 - 0.023 14.4 0.1 2.6 7.7 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 AJW70485.1 - 0.061 12.2 0.0 5.9 5.7 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 AJW70485.1 - 0.082 12.9 0.2 2.3 8.2 0.1 2.9 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SLA_LP_auto_ag PF05889.8 AJW70486.1 - 0.017 13.6 1.0 0.025 13.0 0.7 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Hemocyanin_M PF00372.14 AJW70486.1 - 0.032 13.5 1.4 0.039 13.2 1.0 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Usp PF00582.21 AJW70487.1 - 5e-20 72.1 0.0 6.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family APC10 PF03256.11 AJW70487.1 - 0.14 11.7 0.6 0.93 9.0 0.1 2.0 1 1 0 2 2 2 0 Anaphase-promoting complex, subunit 10 (APC10) Response_reg PF00072.19 AJW70488.1 - 2.1e-10 40.5 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain DUF1487 PF07368.6 AJW70488.1 - 0.0089 15.2 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) DUF3818 PF12825.2 AJW70488.1 - 0.013 14.1 0.3 0.02 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Response_reg PF00072.19 AJW70489.1 - 2.9e-21 75.5 0.2 3.3e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AJW70490.1 - 6.2e-22 77.4 0.0 1.5e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW70490.1 - 4.8e-09 36.0 0.0 1.7e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TarH PF02203.10 AJW70490.1 - 0.0042 16.9 0.2 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 Tar ligand binding domain homologue DUF3175 PF11373.3 AJW70490.1 - 0.063 13.2 0.4 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) DUF4362 PF14275.1 AJW70490.1 - 0.076 13.0 3.0 0.23 11.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4362) Sec20 PF03908.8 AJW70490.1 - 0.2 11.3 2.8 0.39 10.4 0.2 2.7 2 0 0 2 2 2 0 Sec20 ATP-synt_8 PF00895.15 AJW70490.1 - 5.5 7.2 6.2 1.8 8.8 1.2 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 Response_reg PF00072.19 AJW70491.1 - 1.5e-13 50.6 0.1 1.8e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain NHL PF01436.16 AJW70493.1 - 3.1e-15 55.2 1.8 0.02 14.8 0.0 8.0 7 2 2 9 9 9 4 NHL repeat Lactonase PF10282.4 AJW70493.1 - 1.1e-10 41.2 4.1 0.037 13.1 0.1 5.0 1 1 3 5 5 5 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 AJW70493.1 - 1.8e-06 26.5 5.7 0.00033 19.0 1.2 3.3 1 1 2 3 3 3 2 Cytochrome D1 heme domain Arylesterase PF01731.15 AJW70493.1 - 7.7e-06 25.8 14.4 1.5 8.8 0.1 5.4 4 1 1 5 5 5 4 Arylesterase SGL PF08450.7 AJW70493.1 - 0.0009 18.6 2.7 1 8.7 0.0 3.4 1 1 3 4 4 4 4 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 AJW70493.1 - 0.016 14.9 6.4 1.8 8.3 0.1 4.8 4 0 0 4 4 4 0 Beta-propeller repeat DUF2439 PF10382.4 AJW70493.1 - 1.4 9.2 5.3 0.47 10.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2439) Response_reg PF00072.19 AJW70494.1 - 6.4e-26 90.5 0.5 7.6e-26 90.3 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.13 AJW70495.1 - 7.6e-53 178.7 0.4 1.1e-52 178.2 0.3 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.10 AJW70495.1 - 2.5e-08 33.1 0.1 5.4e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_31 PF13847.1 AJW70495.1 - 2.7e-05 23.7 1.3 0.00077 19.0 0.3 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW70495.1 - 0.00043 20.7 0.1 0.0042 17.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain GnsAB PF08178.6 AJW70495.1 - 0.0063 16.1 3.5 0.037 13.6 0.9 3.2 3 0 0 3 3 3 1 GnsA/GnsB family Methyltransf_25 PF13649.1 AJW70495.1 - 0.049 13.9 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 AJW70495.1 - 0.084 13.3 0.0 0.69 10.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF4287 PF14117.1 AJW70495.1 - 0.13 12.0 0.0 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) CheC PF04509.7 AJW70496.1 - 3.4e-13 49.0 2.2 2e-11 43.4 0.0 3.0 3 0 0 3 3 3 2 CheC-like family CheX PF13690.1 AJW70496.1 - 2e-07 30.7 0.4 9.8e-07 28.5 0.0 2.1 1 1 1 2 2 2 1 Chemotaxis phosphatase CheX CheW PF01584.14 AJW70497.1 - 2.7e-23 81.9 0.1 5.4e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.21 AJW70497.1 - 2.1e-19 69.2 1.2 5.3e-19 67.9 0.8 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.18 AJW70497.1 - 5.4e-16 58.3 0.2 2.5e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Hpt domain H-kinase_dim PF02895.9 AJW70497.1 - 2.4e-11 43.8 4.0 2.4e-11 43.8 2.7 2.5 3 0 0 3 3 3 1 Signal transducing histidine kinase, homodimeric domain HATPase_c_3 PF13589.1 AJW70497.1 - 6.7e-05 22.5 0.5 0.00019 21.1 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW70497.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2730 PF10805.3 AJW70497.1 - 0.051 13.3 3.1 0.11 12.2 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FlgD_ig PF13860.1 AJW70497.1 - 0.13 12.0 0.7 0.74 9.5 0.2 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain ALMT PF11744.3 AJW70497.1 - 0.28 9.7 7.9 0.19 10.3 2.9 2.0 1 1 1 2 2 2 0 Aluminium activated malate transporter CheB_methylest PF01339.12 AJW70498.1 - 2.8e-62 209.3 0.2 7.3e-62 208.0 0.1 1.7 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.19 AJW70498.1 - 3.1e-20 72.2 0.3 1.2e-19 70.3 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain CheW PF01584.14 AJW70500.1 - 3.4e-32 110.7 0.1 5.1e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 CheW-like domain Rep-A_N PF04057.7 AJW70500.1 - 0.29 10.9 2.4 0.58 9.9 0.4 2.1 1 1 1 2 2 2 0 Replication factor-A protein 1, N-terminal domain MCPsignal PF00015.16 AJW70501.1 - 7.5e-44 149.8 46.9 3.6e-42 144.3 18.5 2.7 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.1 AJW70501.1 - 1.3e-11 44.8 0.2 7e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 AJW70501.1 - 8.2e-09 35.2 0.3 7.4e-08 32.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 AJW70501.1 - 3.3e-05 23.8 0.0 0.00018 21.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 AJW70501.1 - 0.00013 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Topoisom_I PF01028.15 AJW70501.1 - 0.0045 16.1 2.9 0.0045 16.1 2.0 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core APG17 PF04108.7 AJW70501.1 - 0.4 9.4 16.4 0.099 11.4 3.3 2.8 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF1759 PF03564.10 AJW70501.1 - 1.3 8.7 7.6 0.25 11.1 0.4 3.2 2 2 1 4 4 4 0 Protein of unknown function (DUF1759) Reo_sigmaC PF04582.7 AJW70501.1 - 1.8 7.6 33.6 0.11 11.6 7.1 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Laminin_I PF06008.9 AJW70501.1 - 2.4 7.3 22.6 0.031 13.5 2.0 2.8 2 1 0 2 2 2 0 Laminin Domain I DUF3271 PF11675.3 AJW70502.1 - 0.0055 15.8 0.5 0.011 14.8 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3271) YwiC PF14256.1 AJW70502.1 - 0.047 13.7 1.1 0.12 12.4 0.8 1.8 1 0 0 1 1 1 0 YwiC-like protein Glycoprotein_B PF00606.13 AJW70502.1 - 0.092 10.7 0.0 0.16 9.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF1419 PF07215.6 AJW70502.1 - 0.14 12.0 1.8 8 6.3 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1419) T2SE PF00437.15 AJW70503.1 - 5e-45 153.5 0.0 6.7e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 AJW70504.1 - 1.4e-19 70.1 0.7 1.7e-19 69.8 0.5 1.0 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AJW70504.1 - 1e-06 28.2 0.0 8.4e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain PAXNEB PF05625.6 AJW70504.1 - 4.2e-05 22.5 1.8 0.044 12.6 0.0 2.1 2 0 0 2 2 2 2 PAXNEB protein AAA_18 PF13238.1 AJW70504.1 - 0.00066 19.9 0.2 0.0056 16.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AJW70504.1 - 0.0017 18.2 1.0 0.011 15.6 0.7 2.1 1 1 0 1 1 1 1 AAA domain DUF835 PF05763.7 AJW70504.1 - 0.0064 16.0 0.6 0.01 15.4 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF835) Arch_ATPase PF01637.13 AJW70504.1 - 0.012 15.3 0.2 0.016 14.9 0.2 1.1 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 AJW70504.1 - 0.012 15.2 0.0 0.041 13.5 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Elong_Iki1 PF10483.4 AJW70504.1 - 0.013 14.9 0.2 0.016 14.6 0.2 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 Rad51 PF08423.6 AJW70504.1 - 0.017 14.0 0.1 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad51 DUF2075 PF09848.4 AJW70504.1 - 0.019 13.9 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 AJW70504.1 - 0.038 13.0 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 AJW70504.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 AJW70504.1 - 0.086 13.6 0.1 0.23 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AJW70504.1 - 0.089 12.4 0.1 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AF2331-like PF14556.1 AJW70504.1 - 0.1 12.9 0.2 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 AF2331-like ResIII PF04851.10 AJW70504.1 - 0.1 12.4 0.2 0.15 11.8 0.0 1.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 AJW70504.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Arch_flagellin PF01917.11 AJW70506.1 - 8.9e-06 25.4 6.0 5e-05 23.0 4.1 1.8 1 1 0 1 1 1 1 Archaebacterial flagellin DUF2393 PF09624.5 AJW70506.1 - 0.047 13.2 5.5 0.27 10.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) LPP PF04728.8 AJW70507.1 - 0.042 13.6 0.2 0.7 9.7 0.1 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 AJW70507.1 - 0.05 12.7 0.5 0.081 12.0 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ASFV_J13L PF05568.6 AJW70507.1 - 0.59 9.6 8.4 6.1 6.3 2.2 2.5 1 1 1 2 2 2 0 African swine fever virus J13L protein Cuticle_3 PF11018.3 AJW70507.1 - 4.3 7.4 12.4 30 4.7 8.6 2.0 1 1 0 1 1 1 0 Pupal cuticle protein C1 Arch_flagellin PF01917.11 AJW70508.1 - 9.3e-20 71.0 9.2 1.3e-19 70.6 6.4 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin DUF1628 PF07790.6 AJW70508.1 - 1.7 9.4 7.2 4.5 8.0 4.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1628) Arch_flagellin PF01917.11 AJW70509.1 - 8.1e-14 51.6 3.6 1.2e-13 51.1 2.5 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin Lum_binding PF00677.12 AJW70509.1 - 0.07 13.0 0.3 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Lumazine binding domain Arch_flagellin PF01917.11 AJW70510.1 - 6e-21 74.9 5.5 9.7e-21 74.2 3.8 1.3 1 1 0 1 1 1 1 Archaebacterial flagellin DUF1628 PF07790.6 AJW70510.1 - 7.3 7.4 8.0 9.1 7.1 4.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1628) Arch_flagellin PF01917.11 AJW70511.1 - 1.5e-18 67.0 7.1 2.1e-18 66.6 5.0 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin DUF1628 PF07790.6 AJW70511.1 - 3.4 8.4 7.0 12 6.7 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) Copper-bind PF00127.15 AJW70512.1 - 6.6e-05 23.0 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW70512.1 - 0.044 13.6 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain Arch_flagellin PF01917.11 AJW70513.1 - 2.9e-18 66.1 5.4 3.9e-18 65.7 3.7 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin TrmB PF01978.14 AJW70514.1 - 3.2e-15 55.5 0.0 1.2e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AJW70514.1 - 0.0002 20.4 0.1 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_24 PF13412.1 AJW70514.1 - 0.004 16.5 0.0 0.0081 15.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AJW70514.1 - 0.0065 16.0 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.15 AJW70514.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Anticodon_1 PF08264.8 AJW70514.1 - 0.019 14.7 0.2 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA HTH_Crp_2 PF13545.1 AJW70514.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TPR_2 PF07719.12 AJW70515.1 - 5.1e-53 172.7 16.2 9.9e-06 25.1 0.0 14.1 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_11 PF13414.1 AJW70515.1 - 1e-52 175.6 29.5 2.2e-11 43.2 0.3 8.5 3 2 6 10 10 10 9 TPR repeat TPR_19 PF14559.1 AJW70515.1 - 1.2e-47 160.1 7.4 1.5e-09 38.0 0.1 8.9 5 3 5 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.23 AJW70515.1 - 3.6e-46 152.9 34.0 1.2e-06 27.8 0.9 13.7 15 0 0 15 15 15 10 Tetratricopeptide repeat TPR_16 PF13432.1 AJW70515.1 - 1.1e-45 153.3 0.0 3.8e-08 33.8 0.0 8.7 4 1 7 11 11 11 9 Tetratricopeptide repeat TPR_14 PF13428.1 AJW70515.1 - 1.4e-35 118.4 0.0 5.1e-05 23.5 0.0 12.9 2 2 13 15 15 15 7 Tetratricopeptide repeat Apc3 PF12895.2 AJW70515.1 - 3.3e-34 116.8 25.7 1.4e-08 34.7 0.1 7.4 2 2 5 8 8 8 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AJW70515.1 - 3.3e-31 104.8 25.0 0.0017 18.4 0.2 12.2 14 0 0 14 14 12 8 Tetratricopeptide repeat TPR_6 PF13174.1 AJW70515.1 - 9.9e-31 104.0 10.5 0.0056 17.0 0.0 13.3 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_8 PF13181.1 AJW70515.1 - 3.2e-30 101.6 39.7 0.00011 21.6 0.0 13.1 14 1 1 15 15 14 8 Tetratricopeptide repeat TPR_7 PF13176.1 AJW70515.1 - 2.5e-29 98.7 10.5 0.0076 15.9 0.0 11.6 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_12 PF13424.1 AJW70515.1 - 6.9e-27 93.2 17.6 0.00021 21.1 0.0 9.3 4 3 5 9 9 9 6 Tetratricopeptide repeat TPR_9 PF13371.1 AJW70515.1 - 8.8e-19 67.1 0.0 0.0092 15.8 0.0 7.5 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_20 PF14561.1 AJW70515.1 - 8.8e-15 54.5 3.6 0.016 15.3 0.0 8.3 3 2 5 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.1 AJW70515.1 - 1.2e-09 37.7 1.7 3 7.8 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.3 AJW70515.1 - 1.5e-08 33.8 16.5 0.29 9.8 0.1 6.2 2 2 3 6 6 6 4 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 AJW70515.1 - 7.4e-08 32.1 14.1 2.1 8.3 0.0 9.9 5 3 7 12 12 11 2 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 AJW70515.1 - 2e-07 31.0 3.9 0.17 11.8 0.0 5.6 3 2 3 6 6 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.4 AJW70515.1 - 5.3e-06 26.1 0.7 1.7 8.4 0.0 5.6 3 2 3 6 6 6 2 Rapsyn N-terminal myristoylation and linker region Alkyl_sulf_dimr PF14863.1 AJW70515.1 - 0.00027 21.1 2.6 1.9 8.7 0.1 4.2 3 1 0 4 4 4 1 Alkyl sulfatase dimerisation TPR_15 PF13429.1 AJW70515.1 - 0.00064 18.8 1.5 0.22 10.5 0.0 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat YfiO PF13525.1 AJW70515.1 - 0.0087 15.5 8.8 0.089 12.2 0.1 3.9 2 1 2 4 4 4 1 Outer membrane lipoprotein Orthopox_F14 PF06076.7 AJW70515.1 - 0.012 15.6 0.3 0.042 13.9 0.2 1.9 1 0 0 1 1 1 0 Orthopoxvirus F14 protein TPR_3 PF07720.7 AJW70515.1 - 1.2 8.9 13.9 13 5.7 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Big_1 PF02369.11 AJW70516.1 - 0.051 13.4 10.6 0.35 10.8 0.0 4.5 5 1 0 5 5 5 0 Bacterial Ig-like domain (group 1) Big_2 PF02368.13 AJW70516.1 - 0.99 9.3 8.1 1.9 8.4 0.2 4.0 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 2) Acetone_carb_G PF08882.6 AJW70517.1 - 0.017 15.1 2.1 3.1 7.8 0.1 2.6 2 1 1 3 3 3 0 Acetone carboxylase gamma subunit Peptidase_M10 PF00413.19 AJW70518.1 - 6.1e-09 35.7 0.0 6.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 AJW70518.1 - 1.8e-06 27.4 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.1 AJW70518.1 - 0.0019 18.2 0.1 0.0043 17.1 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 AJW70518.1 - 0.0021 17.0 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin PF01421.14 AJW70518.1 - 0.0092 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 AJW70518.1 - 0.01 16.3 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 AJW70518.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 AJW70518.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AJW70518.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Response_reg PF00072.19 AJW70519.1 - 4.7e-13 49.1 0.0 6.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain FAM180 PF15173.1 AJW70519.1 - 0.08 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 FAM180 family ThiF PF00899.16 AJW70520.1 - 0.049 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 ThiF family Inos-1-P_synth PF01658.12 AJW70520.1 - 0.082 12.7 0.3 0.13 12.1 0.2 1.3 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase YbaJ PF10757.4 AJW70521.1 - 0.043 13.9 0.0 0.052 13.6 0.0 1.3 1 1 0 1 1 1 0 Biofilm formation regulator YbaJ EntA_Immun PF08951.5 AJW70521.1 - 0.05 13.7 1.8 0.066 13.3 1.2 1.3 1 0 0 1 1 1 0 Enterocin A Immunity HTH_Tnp_Tc3_1 PF11427.3 AJW70521.1 - 0.066 12.8 0.4 0.13 11.9 0.1 1.7 1 1 1 2 2 2 0 Tc3 transposase DUF4296 PF14129.1 AJW70521.1 - 0.071 13.2 0.8 0.092 12.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) DUF1059 PF06348.6 AJW70522.1 - 7.9e-08 32.0 0.0 8.2e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) HATPase_c PF02518.21 AJW70524.1 - 3.2e-19 68.6 0.0 6.5e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW70524.1 - 1.5e-07 31.2 1.7 2.2e-07 30.7 0.0 2.1 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW70524.1 - 2.2e-07 30.5 1.1 4.2e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 AJW70524.1 - 0.0093 15.6 0.0 0.032 13.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW70524.1 - 0.011 15.5 0.1 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain DUF1574 PF07611.6 AJW70524.1 - 0.034 13.0 9.1 0.068 12.0 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1574) DIT1_PvcA PF05141.7 AJW70524.1 - 0.14 11.4 12.7 0.031 13.5 6.2 1.6 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein EIAV_Rev PF11129.3 AJW70524.1 - 0.15 12.0 0.3 0.27 11.2 0.2 1.4 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus FRG1 PF06229.7 AJW70524.1 - 4.8 6.5 10.2 8.6 5.7 7.1 1.5 1 0 0 1 1 1 0 FRG1-like family Response_reg PF00072.19 AJW70525.1 - 5.5e-23 81.1 0.2 6.7e-23 80.8 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Cuticle_1 PF08140.6 AJW70526.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Crustacean cuticle protein repeat CopC PF04234.7 AJW70527.1 - 0.13 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 CopC domain Peptidase_S24 PF00717.18 AJW70530.1 - 1.6e-08 34.0 1.3 2.9e-08 33.2 0.9 1.4 1 0 0 1 1 1 1 Peptidase S24-like Cation_ATPase_C PF00689.16 AJW70530.1 - 0.0067 15.9 5.3 0.0067 15.9 3.7 1.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus DUF606 PF04657.8 AJW70530.1 - 0.011 15.8 0.7 0.025 14.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF606 EpsG PF14897.1 AJW70530.1 - 1.4 7.7 16.3 0.31 9.9 7.7 2.2 2 1 1 3 3 3 0 EpsG family DUF1980 PF09323.5 AJW70530.1 - 3.9 7.1 11.1 0.097 12.4 0.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) HATPase_c PF02518.21 AJW70532.1 - 1.7e-19 69.5 0.2 2.9e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 AJW70532.1 - 1.3e-10 40.8 2.9 1.4e-10 40.7 0.5 2.2 1 1 1 2 2 2 1 GHKL domain HisKA PF00512.20 AJW70532.1 - 4.3e-09 36.2 0.0 1.8e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AJW70532.1 - 0.00048 19.7 0.2 0.0016 18.0 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW70532.1 - 0.0038 17.0 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PhoU PF01895.14 AJW70532.1 - 1.4 9.4 14.3 12 6.4 3.4 3.8 2 1 1 3 3 3 0 PhoU domain DUF948 PF06103.6 AJW70532.1 - 6.2 6.7 9.6 0.96 9.3 1.7 3.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Citrate_synt PF00285.16 AJW70534.1 - 1.6e-141 471.2 0.1 1.7e-141 471.0 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase DUF1940 PF09155.5 AJW70534.1 - 0.011 15.6 1.3 0.02 14.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) Imm47 PF15586.1 AJW70534.1 - 0.018 14.8 0.2 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 47 UPF0146 PF03686.8 AJW70534.1 - 0.027 14.2 0.3 0.066 13.0 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0146) DHHA1 PF02272.14 AJW70536.1 - 8.5e-12 44.6 0.3 8.5e-12 44.6 0.2 2.2 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.15 AJW70536.1 - 6.7e-05 22.5 4.1 8.9e-05 22.1 1.9 1.9 2 1 0 2 2 2 1 DHH family YjgF_endoribonc PF14588.1 AJW70537.1 - 2e-32 112.1 0.0 2.2e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 AJW70537.1 - 1e-21 76.9 0.0 1.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.12 AJW70537.1 - 0.081 12.6 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 BON domain Response_reg PF00072.19 AJW70538.1 - 1e-20 73.7 0.3 1.1e-20 73.6 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TrmB PF01978.14 AJW70539.1 - 3.3e-17 61.9 1.0 2.2e-16 59.2 0.2 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AJW70539.1 - 0.00048 19.1 0.1 0.00089 18.2 0.1 1.4 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB Laminin_I PF06008.9 AJW70539.1 - 0.092 12.0 1.5 1.8 7.7 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain I DUF948 PF06103.6 AJW70541.1 - 0.022 14.6 1.2 0.046 13.5 0.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF869 PF05911.6 AJW70541.1 - 0.042 12.1 7.4 0.046 11.9 5.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Cytochrom_B562 PF07361.6 AJW70541.1 - 0.13 12.6 2.9 0.29 11.5 0.1 2.3 2 1 0 2 2 2 0 Cytochrome b562 DUF4351 PF14261.1 AJW70541.1 - 0.16 11.8 1.0 0.34 10.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) TORC_C PF12886.2 AJW70541.1 - 0.24 11.6 2.8 1.1 9.5 0.1 2.6 2 1 0 2 2 2 0 Transducer of regulated CREB activity, C terminus Cytokin_check_N PF10407.4 AJW70541.1 - 0.42 10.2 5.8 0.73 9.5 1.1 2.7 2 1 1 3 3 3 0 Cdc14 phosphatase binding protein N-terminus DUF1664 PF07889.7 AJW70541.1 - 3.4 7.4 6.9 1.7 8.4 1.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) AAA PF00004.24 AJW70542.1 - 1.7e-38 131.7 0.0 6.9e-38 129.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 AJW70542.1 - 7e-10 38.6 1.0 2.1e-09 37.1 0.3 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.9 AJW70542.1 - 1.6e-07 31.4 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AJW70542.1 - 1.2e-06 28.6 0.0 5.8e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AJW70542.1 - 1.4e-05 24.2 0.1 9.1e-05 21.6 0.0 2.3 2 1 0 2 2 2 1 Zeta toxin RuvB_N PF05496.7 AJW70542.1 - 2.5e-05 23.4 0.0 7e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 AJW70542.1 - 4.5e-05 23.2 0.1 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 AJW70542.1 - 7.1e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AJW70542.1 - 8e-05 22.1 0.2 0.0022 17.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 AJW70542.1 - 0.00017 21.4 0.0 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AJW70542.1 - 0.00031 20.7 0.1 0.028 14.4 0.0 3.0 1 1 2 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 AJW70542.1 - 0.00099 19.0 0.0 0.0026 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AJW70542.1 - 0.0021 18.8 0.0 0.0068 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AJW70542.1 - 0.0023 17.6 0.0 2.5 7.7 0.0 2.6 1 1 1 2 2 2 2 Archaeal ATPase AAA_5 PF07728.9 AJW70542.1 - 0.0031 17.2 0.1 0.016 14.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 AJW70542.1 - 0.0032 17.0 0.0 0.023 14.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AJW70542.1 - 0.0038 16.4 0.1 0.0088 15.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AJW70542.1 - 0.0044 16.7 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 AJW70542.1 - 0.0052 16.2 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 AJW70542.1 - 0.0087 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus KAP_NTPase PF07693.9 AJW70542.1 - 0.021 13.8 0.0 0.61 9.0 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain KaiC PF06745.8 AJW70542.1 - 0.04 13.0 0.1 1.6 7.7 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA-ATPase_like PF09820.4 AJW70542.1 - 0.04 13.0 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 Predicted AAA-ATPase AAA_10 PF12846.2 AJW70542.1 - 0.049 13.0 0.0 7.7 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain ResIII PF04851.10 AJW70542.1 - 0.051 13.4 0.1 0.34 10.7 0.0 2.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 AJW70542.1 - 0.054 13.8 0.5 0.24 11.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 AJW70542.1 - 0.076 13.1 0.1 0.33 11.1 0.0 2.2 3 0 0 3 3 1 0 RNA helicase NACHT PF05729.7 AJW70542.1 - 0.081 12.5 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 AJW70542.1 - 0.11 11.4 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 AJW70542.1 - 0.11 11.7 0.2 0.23 10.6 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 AJW70542.1 - 0.14 12.4 0.4 2.8 8.2 0.0 2.8 3 1 0 3 3 3 0 ABC transporter GATase PF00117.23 AJW70543.1 - 7.8e-44 149.4 0.1 1.1e-43 148.9 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 AJW70543.1 - 1.2e-36 125.1 0.0 3.6e-36 123.5 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 AJW70543.1 - 4.1e-08 32.9 0.4 3.4e-06 26.6 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 CARDB PF07705.6 AJW70543.1 - 0.071 13.1 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 CARDB DJ-1_PfpI PF01965.19 AJW70543.1 - 0.087 12.2 0.0 0.2 11.1 0.0 1.7 1 1 0 1 1 1 0 DJ-1/PfpI family TcdB_N PF12918.2 AJW70543.1 - 0.13 12.4 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain NeA_P2 PF12312.3 AJW70543.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CPSase_L_D2 PF02786.12 AJW70544.1 - 1.9e-100 334.4 0.1 3e-73 245.6 0.1 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 AJW70544.1 - 5.9e-39 132.6 0.1 1.3e-38 131.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AJW70544.1 - 2.3e-35 121.9 0.1 1.1e-16 61.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 AJW70544.1 - 7.9e-22 77.4 0.0 8.1e-15 54.8 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 AJW70544.1 - 3.9e-21 75.1 0.6 7.3e-11 41.3 0.0 4.1 3 2 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AJW70544.1 - 3.5e-18 65.5 0.4 2.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AJW70544.1 - 2.7e-13 49.7 1.0 4.1e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 AJW70544.1 - 7.1e-13 48.3 0.0 2.6e-12 46.5 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain GARS_A PF01071.14 AJW70544.1 - 5.7e-11 42.3 0.8 0.00013 21.5 0.0 2.7 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 AJW70544.1 - 2.6e-07 30.6 0.9 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.5 AJW70544.1 - 0.018 14.4 0.0 0.053 12.8 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Vps5 PF09325.5 AJW70544.1 - 0.053 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Vps5 C terminal like Metallophos PF00149.23 AJW70545.1 - 8.6e-09 35.0 1.2 1.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AJW70545.1 - 1.3e-07 31.5 0.2 2.2e-07 30.8 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 AJW70545.1 - 0.004 16.3 0.1 0.27 10.3 0.0 2.1 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily DNA_pol_E_B PF04042.11 AJW70545.1 - 0.051 12.8 0.1 0.16 11.1 0.0 1.8 2 1 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Epimerase_2 PF02350.14 AJW70545.1 - 0.068 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase SWIM PF04434.12 AJW70546.1 - 0.084 12.3 0.3 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 SWIM zinc finger RTC4 PF14474.1 AJW70547.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 RTC4-like domain RecX PF02631.11 AJW70548.1 - 0.023 14.9 0.0 0.064 13.4 0.0 1.7 2 0 0 2 2 2 0 RecX family ATP-synt_F PF01990.12 AJW70549.1 - 1e-14 54.6 0.0 1.1e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Trp_syntA PF00290.15 AJW70549.1 - 0.016 13.7 0.0 0.016 13.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DUF4350 PF14258.1 AJW70549.1 - 0.14 12.3 0.1 0.71 10.1 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4350) ADH_N PF08240.7 AJW70550.1 - 1.8e-24 85.6 1.9 3.2e-24 84.7 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJW70550.1 - 2.7e-20 72.2 0.0 3.6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AJW70550.1 - 4e-05 24.5 0.0 6.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoC PF01791.4 AJW70551.1 - 3.1e-21 75.7 0.0 4.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase ThiG PF05690.9 AJW70551.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG SnoaL_3 PF13474.1 AJW70552.1 - 4.9e-09 36.2 0.0 6.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AJW70552.1 - 9.6e-06 25.7 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 AJW70552.1 - 1.1e-05 25.2 0.1 3.3e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Lumazine_bd_2 PF12893.2 AJW70552.1 - 0.049 14.1 0.0 0.076 13.5 0.0 1.4 1 1 0 1 1 1 0 Putative lumazine-binding TPP_enzyme_N PF02776.13 AJW70553.1 - 1.9e-62 209.7 1.3 4.5e-60 202.0 0.2 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AJW70553.1 - 4.5e-47 159.4 0.8 2e-46 157.3 0.0 2.5 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AJW70553.1 - 4.4e-45 152.8 0.1 1.1e-44 151.5 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DnaA_N PF11638.3 AJW70553.1 - 0.084 12.4 0.6 0.18 11.4 0.4 1.5 1 0 0 1 1 1 0 DnaA N-terminal domain ALS_ss_C PF10369.4 AJW70554.1 - 3.6e-25 87.4 0.3 1.9e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.1 AJW70554.1 - 1.3e-16 60.1 0.0 2.9e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 AJW70554.1 - 4.8e-13 48.2 0.0 9.3e-13 47.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 AJW70554.1 - 0.00032 20.9 0.2 0.00079 19.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain Acylphosphatase PF00708.13 AJW70554.1 - 0.016 15.2 0.2 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Acylphosphatase DUF2344 PF10105.4 AJW70554.1 - 0.072 12.5 0.1 0.095 12.1 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) HMGL-like PF00682.14 AJW70555.1 - 3.4e-76 256.0 0.7 5.7e-76 255.2 0.5 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 AJW70555.1 - 2.6e-29 101.6 1.1 4.8e-29 100.8 0.7 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Glyco_hydro_97 PF10566.4 AJW70555.1 - 0.0025 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 DUF4147 PF13660.1 AJW70555.1 - 0.013 14.6 0.1 0.031 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Iso_dh PF00180.15 AJW70556.1 - 4.5e-103 344.8 0.4 5e-103 344.6 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 AJW70556.1 - 0.00064 19.0 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA DUF3139 PF11337.3 AJW70557.1 - 0.032 14.5 0.3 0.083 13.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) E1-E2_ATPase PF00122.15 AJW70558.1 - 0.0046 16.0 0.7 0.0055 15.7 0.5 1.0 1 0 0 1 1 1 1 E1-E2 ATPase PsbX PF06596.6 AJW70558.1 - 0.029 14.0 1.1 0.059 13.0 0.8 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) RDD PF06271.7 AJW70558.1 - 0.061 13.2 0.4 0.085 12.7 0.3 1.2 1 0 0 1 1 1 0 RDD family DUF4405 PF14358.1 AJW70558.1 - 0.31 11.1 2.3 0.47 10.6 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) tRNA-synt_2 PF00152.15 AJW70560.1 - 1.4e-88 296.8 0.1 2.6e-88 296.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AJW70560.1 - 3.1e-12 46.1 1.7 6e-12 45.2 1.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AJW70560.1 - 0.00057 19.1 0.1 0.1 11.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) KH_5 PF13184.1 AJW70561.1 - 3.9e-09 36.1 0.0 7.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 NusA-like KH domain Cys_rich_KTR PF14205.1 AJW70561.1 - 0.0093 15.4 0.8 3.3 7.2 0.1 2.5 2 0 0 2 2 2 2 Cysteine-rich KTR Ribosomal_S2 PF00318.15 AJW70561.1 - 0.021 14.0 1.0 0.034 13.3 0.1 1.6 1 1 0 2 2 2 0 Ribosomal protein S2 ABC_tran PF00005.22 AJW70562.1 - 3.5e-25 88.8 0.0 4.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 AJW70562.1 - 2.7e-18 66.0 0.3 4.2e-18 65.4 0.2 1.3 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 AJW70562.1 - 2.9e-10 40.5 5.4 1.5e-09 38.2 0.6 2.7 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.14 AJW70562.1 - 0.00072 18.8 1.1 0.0059 15.8 1.1 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 AJW70562.1 - 0.017 14.5 0.4 0.68 9.3 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 AJW70562.1 - 0.044 13.1 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 AJW70562.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 AJW70562.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain End3 PF12761.2 AJW70563.1 - 0.012 15.3 6.6 0.013 15.1 4.5 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Clathrin PF00637.15 AJW70563.1 - 0.016 14.8 1.4 0.016 14.8 0.9 1.7 1 1 0 1 1 1 0 Region in Clathrin and VPS SynMuv_product PF06047.6 AJW70563.1 - 0.02 14.6 4.9 0.023 14.4 3.4 1.1 1 0 0 1 1 1 0 Ras-induced vulval development antagonist TcdA_TcdB PF12919.2 AJW70563.1 - 0.18 10.2 7.4 0.21 10.0 5.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CENP-R PF06729.7 AJW70563.1 - 0.2 11.3 3.8 0.22 11.2 2.6 1.1 1 0 0 1 1 1 0 Kinetochore component, CENP-R WPP PF13943.1 AJW70563.1 - 0.45 10.7 3.0 0.57 10.4 2.1 1.1 1 0 0 1 1 1 0 WPP domain Mit_KHE1 PF10173.4 AJW70563.1 - 0.71 9.6 3.9 0.77 9.5 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Prp18 PF02840.10 AJW70563.1 - 0.74 9.6 6.1 0.86 9.4 4.2 1.0 1 0 0 1 1 1 0 Prp18 domain SNARE_assoc PF09335.6 AJW70565.1 - 1.3e-17 64.0 1.0 1.3e-17 64.0 0.7 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF1290 PF06947.7 AJW70565.1 - 5.6 6.9 6.5 0.63 9.9 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1290) Pur_DNA_glyco PF02245.11 AJW70566.1 - 2.7e-65 218.9 0.1 2.9e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) UDG PF03167.14 AJW70567.1 - 1.7e-36 124.9 0.0 2.2e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PmbA_TldD PF01523.11 AJW70568.1 - 3.1e-69 233.4 0.0 3.7e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Imm49 PF15660.1 AJW70568.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 49 DUF1953 PF09196.5 AJW70568.1 - 0.2 11.3 1.4 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1953) HATPase_c PF02518.21 AJW70570.1 - 2.4e-27 94.8 0.5 2.6e-26 91.5 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW70570.1 - 2.1e-14 53.2 0.0 6.2e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 AJW70570.1 - 7.1e-09 35.7 0.0 7.1e-09 35.7 0.0 2.7 3 0 0 3 3 3 1 HAMP domain HATPase_c_3 PF13589.1 AJW70570.1 - 1.6e-07 31.0 0.1 4.4e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW70570.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HopW1-1 PF15457.1 AJW70570.1 - 0.087 11.8 0.2 0.2 10.6 0.2 1.5 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Hpt PF01627.18 AJW70571.1 - 8.7e-09 35.2 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Hpt domain NAAA-beta PF15508.1 AJW70571.1 - 0.17 12.2 0.5 20 5.6 0.1 2.4 1 1 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Response_reg PF00072.19 AJW70572.1 - 2.9e-26 91.6 0.8 3.3e-26 91.4 0.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Abi_HHR PF07815.9 AJW70572.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Abl-interactor HHR T2SE PF00437.15 AJW70573.1 - 3.7e-12 45.7 0.0 6.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.24 AJW70573.1 - 5.1e-10 38.8 0.1 5.1e-10 38.8 0.1 2.9 3 0 0 3 3 2 1 KH domain KH_2 PF07650.12 AJW70573.1 - 4.5e-07 29.3 0.4 1.9e-06 27.3 0.1 2.3 2 0 0 2 2 1 1 KH domain KH_3 PF13014.1 AJW70573.1 - 5e-07 29.2 2.0 1.1e-06 28.1 0.1 2.7 2 0 0 2 2 2 1 KH domain KH_5 PF13184.1 AJW70573.1 - 6.7e-06 25.8 0.2 3.4e-05 23.5 0.2 2.3 1 0 0 1 1 1 1 NusA-like KH domain PIN_4 PF13638.1 AJW70573.1 - 1.2e-05 25.4 0.1 6.3e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 PIN domain AAA_14 PF13173.1 AJW70573.1 - 4.2e-05 23.4 0.0 0.00014 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJW70573.1 - 0.00019 22.2 0.0 0.00059 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 AJW70573.1 - 0.0004 19.2 0.0 0.00085 18.1 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 AJW70573.1 - 0.00041 20.6 0.1 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AJW70573.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AJW70573.1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 AJW70573.1 - 0.0022 18.2 0.2 0.025 14.8 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 AJW70573.1 - 0.0046 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AJW70573.1 - 0.0096 16.0 0.0 0.033 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AJW70573.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 AJW70573.1 - 0.02 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 AJW70573.1 - 0.023 14.2 0.1 0.065 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 AJW70573.1 - 0.024 14.4 0.4 0.09 12.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AJW70573.1 - 0.031 13.7 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain KTI12 PF08433.5 AJW70573.1 - 0.032 13.4 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 AJW70573.1 - 0.036 12.9 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 AJW70573.1 - 0.041 12.9 0.0 0.097 11.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 AJW70573.1 - 0.043 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AJW70573.1 - 0.053 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 AJW70573.1 - 0.077 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 AJW70573.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Fe_dep_repress PF01325.14 AJW70574.1 - 1.7e-18 66.3 0.3 2.8e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.10 AJW70574.1 - 3.7e-13 48.9 0.0 8e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain TrmB PF01978.14 AJW70574.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.1 AJW70574.1 - 0.00049 20.3 0.0 0.0028 17.9 0.0 2.1 2 1 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.1 AJW70574.1 - 0.0009 18.5 0.0 0.0022 17.3 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AJW70574.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 MarR family DUF2250 PF10007.4 AJW70574.1 - 0.0012 18.7 0.0 0.0023 17.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) LexA_DNA_bind PF01726.11 AJW70574.1 - 0.002 17.6 0.0 0.0078 15.7 0.0 2.0 3 0 0 3 3 2 1 LexA DNA binding domain MarR PF01047.17 AJW70574.1 - 0.0025 17.4 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.1 AJW70574.1 - 0.0038 17.1 0.0 0.098 12.6 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain DUF4423 PF14394.1 AJW70574.1 - 0.0047 16.4 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_45 PF14947.1 AJW70574.1 - 0.0059 16.4 0.5 0.016 15.0 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix HTH_12 PF08461.5 AJW70574.1 - 0.038 13.7 0.1 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_6 PF01418.12 AJW70574.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family PAX PF00292.13 AJW70574.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain HTH_Crp_2 PF13545.1 AJW70574.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain FeoC PF09012.5 AJW70574.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_23 PF13384.1 AJW70574.1 - 0.083 12.5 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.5 AJW70574.1 - 0.12 12.0 0.5 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Rrf2 PF02082.15 AJW70574.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DUF192 PF02643.10 AJW70577.1 - 2.6e-31 107.5 0.0 3.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 4HB_MCP_1 PF12729.2 AJW70578.1 - 0.094 12.0 3.1 0.052 12.8 0.6 1.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction ODV-E18 PF10717.4 AJW70578.1 - 0.13 11.7 2.4 0.21 11.0 1.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 TauE PF01925.14 AJW70579.1 - 7.5e-51 172.8 35.4 8.5e-51 172.7 24.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE SepZ PF06066.6 AJW70579.1 - 7 6.7 10.7 1.5 8.8 0.5 3.2 3 1 0 3 3 3 0 SepZ SnoaL_3 PF13474.1 AJW70580.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain adh_short PF00106.20 AJW70581.1 - 1.5e-28 99.7 0.0 1.7e-21 76.8 0.0 2.6 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 AJW70581.1 - 1.4e-15 57.7 0.1 6.1e-10 39.2 0.0 3.2 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AJW70581.1 - 2.9e-15 56.4 0.0 1.4e-09 37.8 0.0 2.7 2 1 0 2 2 2 2 KR domain Epimerase PF01370.16 AJW70581.1 - 1.7e-06 27.6 0.1 0.00024 20.6 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AJW70581.1 - 0.0015 18.9 2.1 0.0021 18.4 0.2 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 AJW70581.1 - 0.0019 17.1 0.2 0.0038 16.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 AJW70581.1 - 0.0097 15.5 0.1 0.026 14.1 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AJW70581.1 - 0.032 14.3 0.4 0.12 12.4 0.1 2.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 AJW70583.1 - 0.031 13.0 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family tRNA_int_endo PF01974.12 AJW70584.1 - 1e-26 92.5 0.0 1.6e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AJW70584.1 - 2.1e-18 65.6 0.0 3.7e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain PhoU_div PF01865.11 AJW70585.1 - 1.7e-19 69.8 11.2 2e-19 69.5 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 DUF677 PF05055.7 AJW70585.1 - 0.0039 15.9 0.7 0.0039 15.9 0.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF677) LXG PF04740.7 AJW70585.1 - 0.0043 16.8 6.6 0.017 14.9 0.2 2.6 1 1 1 2 2 2 1 LXG domain of WXG superfamily DUF458 PF04308.7 AJW70585.1 - 0.0081 15.8 4.8 0.16 11.6 0.7 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF458) Reo_sigmaC PF04582.7 AJW70585.1 - 0.075 12.1 3.9 0.19 10.8 2.5 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein ELL PF10390.4 AJW70585.1 - 0.19 10.9 1.3 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL PhoU PF01895.14 AJW70585.1 - 0.22 12.0 14.8 0.46 10.9 3.4 3.1 2 2 1 3 3 3 0 PhoU domain MCPsignal PF00015.16 AJW70585.1 - 0.38 10.2 11.4 6.7 6.1 6.5 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Pox_A_type_inc PF04508.7 AJW70585.1 - 1.3 8.9 5.1 3 7.8 0.5 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlxA PF14282.1 AJW70585.1 - 7.7 6.5 8.9 11 6.0 1.0 2.5 2 1 0 2 2 2 0 FlxA-like protein DNA_ligase_A_M PF01068.16 AJW70586.1 - 8.2e-57 191.8 2.4 1.4e-56 191.1 1.6 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AJW70586.1 - 5.2e-51 172.9 3.4 6.7e-51 172.5 1.3 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AJW70586.1 - 1.2e-21 76.9 0.0 2.4e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 AJW70586.1 - 0.079 12.6 0.3 0.37 10.4 0.0 2.2 3 0 0 3 3 3 0 DNA ligase OB-like domain KOW PF00467.24 AJW70587.1 - 0.004 16.8 0.8 0.0058 16.2 0.2 1.7 2 0 0 2 2 2 1 KOW motif DUF2373 PF10180.4 AJW70588.1 - 0.038 13.5 0.2 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) FBPase_3 PF01950.11 AJW70589.1 - 4.2e-158 526.1 0.1 4.7e-158 525.9 0.1 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase DUF1989 PF09347.5 AJW70589.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) GTP_EFTU PF00009.22 AJW70590.1 - 9.6e-49 165.3 0.1 1.4e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AJW70590.1 - 3.5e-31 107.2 0.8 9.8e-31 105.8 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AJW70590.1 - 7.5e-17 61.2 0.6 2.2e-16 59.7 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AJW70590.1 - 4e-06 26.3 0.7 8.2e-06 25.3 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AJW70590.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase NIF3 PF01784.13 AJW70590.1 - 0.11 12.0 0.3 0.24 10.9 0.1 1.7 2 0 0 2 2 2 0 NIF3 (NGG1p interacting factor 3) Ribosomal_S10 PF00338.17 AJW70591.1 - 2.2e-25 88.3 0.0 2.4e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DNA_RNApol_7kD PF03604.8 AJW70592.1 - 3.8e-05 23.0 1.4 6.4e-05 22.3 1.0 1.4 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-HIT PF04438.11 AJW70592.1 - 0.076 12.6 1.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2 PF00096.21 AJW70593.1 - 2.2e-10 40.2 8.2 2.1e-05 24.5 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AJW70593.1 - 4.3e-09 36.0 4.0 0.00058 20.0 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AJW70593.1 - 8.2e-08 32.1 10.3 0.00018 21.5 0.9 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 AJW70593.1 - 1.8e-06 27.8 10.4 0.00033 20.6 0.8 2.3 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-met PF12874.2 AJW70593.1 - 1e-05 25.5 5.3 0.017 15.2 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 AJW70593.1 - 5.1e-05 23.3 12.9 0.0048 17.1 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain DUF629 PF04780.7 AJW70593.1 - 6.1e-05 21.7 9.2 0.0097 14.4 1.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 AJW70593.1 - 0.00057 19.7 6.3 0.14 12.1 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AJW70593.1 - 0.0019 18.3 11.1 0.13 12.4 2.0 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Endonuclease_7 PF02945.10 AJW70593.1 - 0.0045 16.6 1.3 0.0059 16.2 0.9 1.2 1 0 0 1 1 1 1 Recombination endonuclease VII C1_4 PF07975.7 AJW70593.1 - 0.0064 16.4 2.4 0.009 16.0 1.7 1.3 1 0 0 1 1 1 1 TFIIH C1-like domain RIG-I_C-RD PF11648.3 AJW70593.1 - 0.013 15.3 1.9 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I PyrI_C PF02748.10 AJW70593.1 - 0.021 14.2 5.2 0.073 12.5 0.2 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Prok-RING_1 PF14446.1 AJW70593.1 - 0.027 14.2 4.3 0.3 10.8 0.5 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF866 PF05907.8 AJW70593.1 - 0.031 13.7 5.1 0.033 13.6 3.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Cor1 PF04803.7 AJW70593.1 - 0.035 13.8 4.8 0.039 13.7 3.3 1.1 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Zn-ribbon_8 PF09723.5 AJW70593.1 - 0.04 13.8 5.8 1.7 8.6 0.4 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-CHY PF05495.7 AJW70593.1 - 0.04 14.0 2.6 0.073 13.2 1.8 1.4 1 0 0 1 1 1 0 CHY zinc finger DUF3505 PF12013.3 AJW70593.1 - 0.042 14.0 2.9 0.073 13.3 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) Mu-like_Com PF10122.4 AJW70593.1 - 0.047 12.7 0.3 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-3CxxC PF13695.1 AJW70593.1 - 0.077 13.2 2.8 0.098 12.8 1.9 1.2 1 0 0 1 1 1 0 Zinc-binding domain zf-Di19 PF05605.7 AJW70593.1 - 0.094 12.8 5.4 0.94 9.6 0.3 1.9 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.1 AJW70593.1 - 0.1 12.3 3.0 0.25 11.0 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 AJW70593.1 - 0.11 12.3 9.6 0.34 10.6 1.2 2.4 1 1 1 2 2 2 0 BED zinc finger HypA PF01155.14 AJW70593.1 - 0.11 12.2 0.8 0.15 11.7 0.5 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-HIT PF04438.11 AJW70593.1 - 0.11 12.1 2.6 2.3 7.9 0.2 2.2 2 0 0 2 2 2 0 HIT zinc finger Cytochrom_CIII PF02085.11 AJW70593.1 - 0.12 12.5 5.0 0.13 12.3 3.4 1.2 1 0 0 1 1 1 0 Class III cytochrome C family zinc_ribbon_5 PF13719.1 AJW70593.1 - 0.14 11.7 3.3 0.25 10.9 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain SIR2 PF02146.12 AJW70593.1 - 0.17 11.5 3.6 0.71 9.5 1.9 1.9 1 1 1 2 2 2 0 Sir2 family Ribosomal_L44 PF00935.14 AJW70593.1 - 0.18 11.8 4.7 2.7 8.0 1.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L44 C1_2 PF03107.11 AJW70593.1 - 0.23 11.6 4.4 0.97 9.6 0.1 2.2 2 0 0 2 2 2 0 C1 domain Transpos_assoc PF13963.1 AJW70593.1 - 0.25 11.3 6.2 1.6 8.8 0.3 2.1 1 1 1 2 2 2 0 Transposase-associated domain Rep_fac-A_C PF08646.5 AJW70593.1 - 0.31 10.7 5.3 0.68 9.6 3.7 1.5 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-FCS PF06467.9 AJW70593.1 - 0.34 10.5 4.5 6.5 6.4 0.4 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc-ribbons_6 PF07191.7 AJW70593.1 - 0.48 10.2 4.8 2.5 7.9 3.3 1.9 1 1 1 2 2 2 0 zinc-ribbons DUF951 PF06107.6 AJW70593.1 - 0.55 9.7 5.2 3.9 7.0 0.7 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Evr1_Alr PF04777.8 AJW70593.1 - 0.99 9.3 6.7 2.5 8.0 0.8 2.0 1 1 1 2 2 2 0 Erv1 / Alr family SAE2 PF08573.5 AJW70593.1 - 1.5 9.5 6.5 57 4.5 4.5 2.1 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus XPA_N PF01286.13 AJW70593.1 - 3.6 7.3 8.1 0.97 9.1 1.6 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-AN1 PF01428.11 AJW70593.1 - 3.9 7.4 9.4 4.1 7.3 0.1 2.5 3 0 0 3 3 2 0 AN1-like Zinc finger zf-DBF PF07535.7 AJW70593.1 - 5.3 6.7 7.8 54 3.5 5.4 2.1 1 1 0 1 1 1 0 DBF zinc finger FYVE PF01363.16 AJW70593.1 - 6.4 6.7 7.2 29 4.6 0.7 2.0 1 1 1 2 2 2 0 FYVE zinc finger Ribosomal_S14 PF00253.16 AJW70594.1 - 0.0035 16.7 8.5 0.32 10.4 2.2 3.4 3 1 0 3 3 3 2 Ribosomal protein S14p/S29e FYVE PF01363.16 AJW70594.1 - 0.0058 16.5 14.2 23 4.9 9.9 2.9 1 1 0 1 1 1 0 FYVE zinc finger zf-C4pol PF14260.1 AJW70594.1 - 0.0087 16.0 10.6 1 9.3 0.6 3.3 2 1 0 2 2 2 2 C4-type zinc-finger of DNA polymerase delta zf-CHY PF05495.7 AJW70594.1 - 0.021 14.9 18.8 0.14 12.3 3.4 3.0 1 1 0 3 3 3 0 CHY zinc finger Cytochrome_C7 PF14522.1 AJW70594.1 - 0.16 11.6 18.6 0.067 12.8 3.2 3.0 1 1 2 3 3 3 0 Cytochrome c7 DUF4428 PF14471.1 AJW70594.1 - 0.17 11.6 21.8 0.2 11.4 0.6 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4428) C1_1 PF00130.17 AJW70594.1 - 0.27 10.9 18.5 0.14 11.8 1.4 3.3 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cytochrom_c3_2 PF14537.1 AJW70594.1 - 3.7 7.9 17.1 1.3e+02 2.9 11.9 3.0 1 1 0 1 1 1 0 Cytochrome c3 PHF5 PF03660.9 AJW70594.1 - 5.8 7.0 9.0 2.7 8.0 2.7 2.4 1 1 1 2 2 2 0 PHF5-like protein RHH_1 PF01402.16 AJW70595.1 - 0.13 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Lysine_decarbox PF03641.9 AJW70596.1 - 9.3e-06 25.4 0.4 5.4e-05 23.0 0.3 2.1 1 1 0 1 1 1 1 Possible lysine decarboxylase DNA_processg_A PF02481.10 AJW70596.1 - 0.00052 18.9 0.6 0.0085 15.0 0.1 2.2 2 1 0 2 2 2 1 DNA recombination-mediator protein A DAGK_cat PF00781.19 AJW70596.1 - 0.023 14.1 2.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Spermine_synth PF01564.12 AJW70596.1 - 0.58 9.0 3.3 0.89 8.4 0.1 2.2 2 1 1 3 3 2 0 Spermine/spermidine synthase 3HCDH_N PF02737.13 AJW70597.1 - 6.2e-66 221.4 0.9 6.2e-66 221.4 0.6 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AJW70597.1 - 7e-35 119.3 0.1 6.4e-26 90.6 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 AJW70597.1 - 7.6e-08 32.2 0.1 1.4e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 AJW70597.1 - 1.7e-06 27.9 0.0 3.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AJW70597.1 - 0.00022 21.6 0.1 0.00069 20.0 0.1 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 AJW70597.1 - 0.031 13.6 0.2 0.058 12.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4078 PF13300.1 AJW70597.1 - 0.044 13.9 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) IlvN PF07991.7 AJW70597.1 - 1.7 7.9 4.4 68 2.7 3.1 2.3 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain zf-BED PF02892.10 AJW70598.1 - 0.00013 21.6 0.8 0.00019 21.1 0.6 1.2 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.21 AJW70598.1 - 0.0035 17.5 1.0 0.0058 16.8 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type Rad50_zn_hook PF04423.9 AJW70598.1 - 0.0098 15.3 0.6 0.013 14.9 0.5 1.2 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-C2H2_2 PF12756.2 AJW70598.1 - 0.011 15.8 0.2 0.011 15.7 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 AJW70598.1 - 0.051 13.9 0.3 0.084 13.2 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 AJW70598.1 - 0.28 11.4 2.8 0.4 11.0 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain HIT PF01230.18 AJW70600.1 - 3.6e-23 81.9 1.0 4.5e-23 81.6 0.7 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AJW70600.1 - 3.8e-14 52.9 0.7 5.2e-14 52.4 0.5 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AJW70600.1 - 0.00021 20.9 0.2 0.00027 20.5 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.12 AJW70600.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Cas_NE0113 PF09623.5 AJW70600.1 - 0.086 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) DnaJ PF00226.26 AJW70601.1 - 2.2e-19 68.9 1.6 5.1e-19 67.7 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain Fer4_15 PF13459.1 AJW70601.1 - 4.5e-11 43.1 2.5 4.5e-11 43.1 1.8 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_13 PF13370.1 AJW70601.1 - 2.1e-10 40.8 3.0 2.1e-10 40.8 2.1 2.1 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_19 PF06902.6 AJW70601.1 - 0.0021 17.8 3.0 0.0069 16.1 2.1 1.8 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_7 PF12838.2 AJW70601.1 - 0.016 15.5 0.5 0.26 11.7 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain NUMOD1 PF07453.8 AJW70601.1 - 0.03 14.1 1.1 0.53 10.2 0.5 2.6 2 0 0 2 2 2 0 NUMOD1 domain RPT PF13446.1 AJW70601.1 - 0.036 13.4 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein Fer4 PF00037.22 AJW70601.1 - 0.11 12.1 10.9 0.31 10.7 4.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 AJW70601.1 - 0.13 12.2 4.2 0.28 11.1 2.9 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_18 PF13746.1 AJW70601.1 - 0.13 12.7 0.2 0.13 12.7 0.1 2.7 3 1 0 3 3 3 0 4Fe-4S dicluster domain Cupin_2 PF07883.6 AJW70602.1 - 1.7e-12 46.6 0.0 3.2e-12 45.7 0.0 1.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 AJW70602.1 - 1.3e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.13 AJW70602.1 - 2.6e-05 23.8 0.0 3.9e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.7 AJW70602.1 - 0.00014 21.1 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 AJW70602.1 - 0.00016 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Ectoine_synth PF06339.7 AJW70602.1 - 0.0027 17.6 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Ectoine synthase Cupin_5 PF06172.6 AJW70602.1 - 0.071 13.0 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Cupin superfamily (DUF985) GPI PF06560.6 AJW70602.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.6 AJW70603.1 - 1.6e-07 30.6 0.6 8.1e-07 28.4 0.4 1.9 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.11 AJW70603.1 - 2.3e-05 23.9 0.1 2.6e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Auxin binding protein Cupin_1 PF00190.17 AJW70603.1 - 0.00015 21.2 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 AJW70603.1 - 0.013 15.0 0.1 0.033 13.6 0.0 1.6 1 1 1 2 2 2 0 Cupin-like domain DUF4320 PF14208.1 AJW70603.1 - 0.042 13.8 0.3 0.087 12.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) AraC_binding PF02311.14 AJW70603.1 - 0.092 12.4 0.1 0.28 10.8 0.1 1.7 1 1 0 1 1 1 0 AraC-like ligand binding domain SHOCT PF09851.4 AJW70604.1 - 4.5e-08 32.2 3.4 4.5e-08 32.2 2.4 2.8 3 0 0 3 3 3 1 Short C-terminal domain ATP-synt_B PF00430.13 AJW70604.1 - 0.00067 19.4 9.5 0.001 18.8 6.6 1.3 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DUF1707 PF08044.6 AJW70604.1 - 0.038 13.7 0.2 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) DUF2680 PF10925.3 AJW70604.1 - 0.052 13.4 2.4 0.19 11.6 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2680) ApoLp-III PF07464.6 AJW70604.1 - 0.78 9.7 11.9 0.94 9.4 8.2 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_13 PF13166.1 AJW70604.1 - 1.2 7.4 12.6 1.5 7.2 8.7 1.0 1 0 0 1 1 1 0 AAA domain DMAP_binding PF06464.6 AJW70604.1 - 3.7 8.2 7.3 1.3 9.6 1.2 2.3 1 1 0 2 2 2 0 DMAP1-binding Domain LUC7 PF03194.10 AJW70604.1 - 6.4 6.2 8.0 12 5.3 5.6 1.6 1 1 0 1 1 1 0 LUC7 N_terminus Toprim_Crpt PF13342.1 AJW70605.1 - 0.0072 15.9 0.1 0.0072 15.9 0.1 2.1 2 0 0 2 2 2 1 C-terminal repeat of topoisomerase TPR_11 PF13414.1 AJW70606.1 - 2e-54 181.1 26.6 4.5e-15 55.0 0.9 4.5 1 1 5 6 6 6 6 TPR repeat TPR_1 PF00515.23 AJW70606.1 - 8.4e-39 129.6 18.9 7e-08 31.7 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 AJW70606.1 - 1.2e-37 124.7 9.0 1.8e-06 27.4 0.6 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 AJW70606.1 - 5.5e-32 107.2 9.3 3.1e-06 26.9 0.1 6.7 6 1 2 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 AJW70606.1 - 5.7e-29 100.1 0.0 1.1e-07 32.3 0.7 4.9 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 AJW70606.1 - 1.2e-27 95.5 9.7 3.8e-08 33.1 0.9 4.6 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 AJW70606.1 - 3e-25 86.4 0.0 0.0052 17.2 0.1 7.1 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.1 AJW70606.1 - 3e-24 83.7 3.0 0.0081 16.5 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 AJW70606.1 - 6.2e-21 72.5 12.8 0.00023 20.7 0.0 7.2 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJW70606.1 - 1.9e-20 72.9 5.8 1.3e-05 25.4 0.4 4.6 3 1 2 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 AJW70606.1 - 3.1e-15 56.0 4.4 6.1e-05 23.0 0.0 3.5 3 1 1 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AJW70606.1 - 7.6e-15 54.5 0.0 1.3e-06 28.2 0.0 4.2 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 AJW70606.1 - 9e-14 50.1 0.1 0.031 14.0 0.0 6.4 6 1 1 7 7 6 3 Tetratricopeptide repeat NARP1 PF12569.3 AJW70606.1 - 8.2e-12 44.6 5.3 8e-05 21.5 0.1 3.0 1 1 2 3 3 3 3 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 AJW70606.1 - 4.8e-07 29.8 4.9 0.12 12.5 0.1 4.5 1 1 4 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 AJW70606.1 - 8.3e-07 28.7 15.4 1.5 8.7 1.6 6.2 4 2 2 6 6 6 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 AJW70606.1 - 6.7e-06 25.8 11.1 0.24 11.3 0.0 6.2 4 3 3 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.9 AJW70606.1 - 7.7e-06 25.3 2.7 0.14 11.3 0.1 3.2 1 1 2 3 3 3 2 Coatomer epsilon subunit TPR_10 PF13374.1 AJW70606.1 - 0.00026 20.7 5.9 43 4.2 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 AJW70606.1 - 0.00034 20.3 1.0 2.9 8.0 0.0 5.1 5 0 0 5 5 5 1 PPR repeat DUF3856 PF12968.2 AJW70606.1 - 0.0008 19.2 0.3 23 4.7 0.0 4.4 2 2 3 5 5 5 0 Domain of Unknown Function (DUF3856) Rapsyn_N PF10579.4 AJW70606.1 - 0.001 18.7 0.1 2.3 8.0 0.0 4.2 1 1 2 4 4 4 1 Rapsyn N-terminal myristoylation and linker region BTAD PF03704.12 AJW70606.1 - 0.0034 17.6 0.0 2.2 8.5 0.0 3.5 2 1 2 4 4 4 1 Bacterial transcriptional activator domain Thioredoxin_6 PF13848.1 AJW70606.1 - 0.0047 16.7 1.1 0.41 10.4 0.1 3.1 3 1 0 3 3 3 1 Thioredoxin-like domain RPN7 PF10602.4 AJW70606.1 - 0.0098 15.2 0.4 0.76 9.1 0.1 3.3 1 1 2 3 3 3 1 26S proteasome subunit RPN7 FAT PF02259.18 AJW70606.1 - 0.036 13.0 0.6 0.25 10.2 0.0 2.2 1 1 0 2 2 2 0 FAT domain TOM20_plant PF06552.7 AJW70606.1 - 0.064 12.8 3.0 7.6 6.0 0.1 3.8 1 1 3 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Apc5 PF12862.2 AJW70606.1 - 0.071 12.9 1.1 0.62 9.9 0.2 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.7 AJW70606.1 - 0.12 12.1 3.6 55 3.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.15 AJW70606.1 - 0.41 10.2 5.0 8.5 5.9 1.4 3.6 1 1 2 3 3 3 0 Region in Clathrin and VPS DUF11 PF01345.13 AJW70608.1 - 4.2e-37 126.0 25.3 1e-16 60.7 3.0 9.9 10 1 0 10 10 10 3 Domain of unknown function DUF11 HYR PF02494.11 AJW70608.1 - 2.2e-35 120.5 79.9 1.7e-16 60.0 0.8 10.6 11 0 0 11 11 11 7 HYR domain Calx-beta PF03160.9 AJW70608.1 - 4.2e-09 36.2 0.7 4.2e-09 36.2 0.5 2.9 2 0 0 2 2 2 1 Calx-beta domain TRAP_beta PF05753.9 AJW70608.1 - 3.3e-07 29.6 1.2 0.16 11.0 0.0 3.7 3 0 0 3 3 3 2 Translocon-associated protein beta (TRAPB) CARDB PF07705.6 AJW70608.1 - 1.2e-06 28.4 24.9 0.012 15.6 3.1 6.9 5 1 0 5 5 5 3 CARDB Big_3_4 PF13754.1 AJW70608.1 - 0.00064 19.9 12.6 0.00064 19.9 8.8 15.6 13 4 0 13 13 13 6 Bacterial Ig-like domain (group 3) He_PIG PF05345.7 AJW70608.1 - 0.0019 18.1 4.2 0.0019 18.1 2.9 14.3 14 3 0 14 14 14 1 Putative Ig domain DUF4398 PF14346.1 AJW70608.1 - 0.25 11.3 12.5 0.018 15.0 4.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) HATPase_c PF02518.21 AJW70609.1 - 7e-23 80.4 0.7 6.9e-22 77.2 0.0 2.5 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW70609.1 - 3.6e-12 46.1 0.4 6.1e-12 45.3 0.1 1.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW70609.1 - 6.9e-11 41.7 0.3 2.4e-10 39.9 0.0 2.1 2 1 1 3 3 3 1 GHKL domain HATPase_c_3 PF13589.1 AJW70609.1 - 4e-06 26.5 1.6 4.3e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW70609.1 - 0.0035 17.1 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain AP4E_app_platf PF14807.1 AJW70609.1 - 0.074 13.2 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform FlaC_arch PF05377.6 AJW70609.1 - 0.67 9.8 0.1 0.67 9.8 0.1 3.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF2972 PF11186.3 AJW70609.1 - 5.3 6.8 9.9 25 4.6 6.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) Trypan_PARP PF05887.6 AJW70610.1 - 5.1 6.9 18.4 13 5.6 12.7 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Adeno_PIX PF03955.9 AJW70611.1 - 0.71 10.4 4.2 0.56 10.7 0.8 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Kinetocho_Slk19 PF12709.2 AJW70613.1 - 0.0077 16.2 4.1 0.019 15.0 2.8 1.6 1 1 0 1 1 1 1 Central kinetochore-associated MgsA_C PF12002.3 AJW70613.1 - 0.0087 15.7 0.1 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal DUF445 PF04286.7 AJW70613.1 - 0.024 14.1 0.2 0.024 14.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YpjP PF14005.1 AJW70613.1 - 0.035 13.8 0.6 1.4 8.7 0.1 2.0 1 1 1 2 2 2 0 YpjP-like protein DUF2294 PF10057.4 AJW70613.1 - 0.037 13.6 0.1 0.76 9.4 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) VEGF_C PF14554.1 AJW70614.1 - 0.14 12.0 0.1 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 VEGF heparin-binding domain Peptidase_M10 PF00413.19 AJW70615.1 - 5.2e-09 35.9 0.7 7.3e-09 35.5 0.5 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 AJW70615.1 - 2.4e-05 23.9 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 AJW70615.1 - 0.00077 19.1 3.2 0.0016 18.0 0.1 2.2 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 AJW70615.1 - 0.00091 19.7 0.1 0.0017 18.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 AJW70615.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 AJW70615.1 - 0.0016 17.7 0.6 0.0025 17.1 0.0 1.6 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.1 AJW70615.1 - 0.0032 17.4 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 AJW70615.1 - 0.0045 15.9 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 Astacin PF01400.19 AJW70615.1 - 0.0071 15.7 0.6 0.027 13.8 0.1 2.0 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Metallopep PF12044.3 AJW70615.1 - 0.0099 14.3 0.0 0.018 13.4 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M43 PF05572.8 AJW70615.1 - 0.05 13.1 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A HxlR PF01638.12 AJW70616.1 - 8.4e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 1 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.9 AJW70616.1 - 0.0054 16.4 0.0 0.024 14.3 0.0 1.9 1 1 1 2 2 2 1 Transcriptional regulator PadR-like family HTH_34 PF13601.1 AJW70616.1 - 0.033 14.2 0.0 0.33 10.9 0.0 2.1 1 1 1 2 2 2 0 Winged helix DNA-binding domain Melibiase PF02065.13 AJW70617.1 - 0.072 11.7 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Melibiase Aminotran_3 PF00202.16 AJW70619.1 - 4.3e-56 190.1 0.0 5.3e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUP PF00674.13 AJW70621.1 - 0.047 13.6 0.2 0.047 13.6 0.1 1.1 1 0 0 1 1 1 0 DUP family DUF2180 PF09947.4 AJW70623.1 - 0.095 12.4 4.2 0.17 11.6 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Tnp_zf-ribbon_2 PF13842.1 AJW70623.1 - 0.26 11.7 4.1 3.3 8.1 0.4 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.2 AJW70624.1 - 0.00018 21.2 0.5 0.00021 21.0 0.3 1.1 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 AJW70624.1 - 0.0017 18.0 0.6 0.0017 18.0 0.4 1.0 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-C2H2_6 PF13912.1 AJW70624.1 - 0.0028 17.4 2.7 0.076 12.9 0.1 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger RRN7 PF11781.3 AJW70624.1 - 0.0041 16.5 2.3 0.91 9.0 0.6 2.1 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 TFIIS_C PF01096.13 AJW70624.1 - 0.0042 16.6 3.1 0.013 15.1 0.3 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zinc-ribbons_6 PF07191.7 AJW70624.1 - 0.0083 15.8 0.5 0.009 15.7 0.3 1.1 1 0 0 1 1 1 1 zinc-ribbons FYVE PF01363.16 AJW70624.1 - 0.0088 15.9 0.5 0.0098 15.7 0.4 1.1 1 0 0 1 1 1 1 FYVE zinc finger TF_Zn_Ribbon PF08271.7 AJW70624.1 - 0.013 14.7 2.4 0.15 11.4 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 AJW70624.1 - 0.019 14.4 5.5 0.17 11.3 0.3 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 AJW70624.1 - 0.021 14.2 3.1 0.12 11.8 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 AJW70624.1 - 0.04 13.5 0.8 0.047 13.3 0.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 AJW70624.1 - 0.051 13.4 0.9 0.052 13.4 0.6 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 AJW70624.1 - 0.07 12.8 1.8 0.1 12.3 1.3 1.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 UPF0547 PF10571.4 AJW70624.1 - 0.1 12.3 3.5 0.22 11.2 0.2 2.0 1 1 1 2 2 1 0 Uncharacterised protein family UPF0547 zf-C2H2 PF00096.21 AJW70624.1 - 0.1 12.9 2.9 0.38 11.2 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2321 PF10083.4 AJW70624.1 - 0.1 12.0 0.8 0.12 11.8 0.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-B_box PF00643.19 AJW70624.1 - 0.11 12.4 2.9 0.34 10.8 2.0 1.7 1 1 0 1 1 1 0 B-box zinc finger zf-RING_5 PF14634.1 AJW70624.1 - 0.11 12.2 1.2 0.15 11.7 0.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.1 AJW70624.1 - 0.14 11.4 3.6 0.31 10.3 2.5 1.6 1 1 1 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 AJW70624.1 - 0.18 11.5 1.3 0.31 10.8 0.9 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_POL_M_15KD PF02150.11 AJW70624.1 - 0.2 11.3 2.6 0.63 9.7 0.1 2.1 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit DUF2318 PF10080.4 AJW70624.1 - 0.21 11.3 1.3 0.31 10.8 0.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-CHY PF05495.7 AJW70624.1 - 0.23 11.6 2.1 0.37 10.9 1.5 1.3 1 1 0 1 1 1 0 CHY zinc finger DNA_RNApol_7kD PF03604.8 AJW70624.1 - 0.25 10.8 3.0 0.6 9.6 2.1 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 AJW70624.1 - 0.35 10.8 3.0 2.9 7.9 2.1 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-trcl PF13451.1 AJW70624.1 - 0.47 10.1 4.0 1.3 8.7 0.3 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain zf-C2H2_4 PF13894.1 AJW70624.1 - 0.85 10.1 3.9 1.7 9.1 0.2 2.1 1 1 1 2 2 2 0 C2H2-type zinc finger Tnp_zf-ribbon_2 PF13842.1 AJW70624.1 - 0.9 10.0 7.6 8.4 6.8 0.4 2.1 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon ADK_lid PF05191.9 AJW70624.1 - 0.92 9.2 3.0 14 5.4 2.1 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-HIT PF04438.11 AJW70624.1 - 0.96 9.1 4.7 1.8 8.2 1.1 2.1 1 1 1 2 2 2 0 HIT zinc finger Nudix_N_2 PF14803.1 AJW70624.1 - 1.9 8.2 4.4 74 3.1 3.1 2.1 1 1 0 1 1 1 0 Nudix N-terminal Rpr2 PF04032.11 AJW70624.1 - 2.1 8.2 5.6 7.8 6.4 0.3 2.0 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_2 PF03107.11 AJW70624.1 - 3.7 7.7 7.1 4 7.6 0.8 2.1 1 1 0 2 2 2 0 C1 domain HATPase_c PF02518.21 AJW70626.1 - 1.2e-24 86.1 0.1 2.3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 AJW70626.1 - 2.7e-24 85.5 0.1 1.1e-23 83.5 0.1 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 AJW70626.1 - 1.4e-14 53.8 0.0 4.4e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 AJW70626.1 - 3.3e-10 39.9 0.0 6.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 AJW70626.1 - 4.7e-10 39.4 0.1 9.2e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.1 AJW70626.1 - 2.7e-09 36.6 0.1 8.2e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 GHKL domain HisKA PF00512.20 AJW70626.1 - 1.4e-08 34.5 0.0 3.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AJW70626.1 - 6.2e-05 22.6 0.1 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW70626.1 - 7.7e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_8 PF13188.1 AJW70626.1 - 0.011 15.6 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.2 AJW70626.1 - 0.039 13.9 0.0 0.37 10.8 0.0 2.5 1 1 1 2 2 2 0 PAS fold RDD PF06271.7 AJW70627.1 - 4.3e-22 78.4 2.2 5.1e-22 78.2 1.5 1.1 1 0 0 1 1 1 1 RDD family LIM PF00412.17 AJW70628.1 - 0.094 12.7 1.0 0.12 12.4 0.7 1.1 1 0 0 1 1 1 0 LIM domain Vps39_2 PF10367.4 AJW70628.1 - 0.11 12.6 0.2 0.11 12.6 0.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Methyltransf_11 PF08241.7 AJW70629.1 - 1.7e-10 41.2 0.0 3.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW70629.1 - 3.2e-07 30.2 0.0 6.5e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW70629.1 - 0.0022 17.5 0.0 0.0061 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AJW70629.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.7 AJW70629.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Baculo_Y142 PF04913.7 AJW70629.1 - 0.022 13.1 0.7 0.036 12.4 0.5 1.3 1 0 0 1 1 1 0 Baculovirus Y142 protein Robl_LC7 PF03259.12 AJW70631.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain A2M_N PF01835.14 AJW70632.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 MG2 domain PMSR PF01625.16 AJW70633.1 - 2e-66 222.6 0.9 2.4e-66 222.4 0.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.10 AJW70633.1 - 0.07 12.7 0.0 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Protocadherin PF08374.6 AJW70633.1 - 0.12 11.9 0.2 0.66 9.5 0.0 1.8 1 1 1 2 2 2 0 Protocadherin HMA PF00403.21 AJW70633.1 - 0.14 12.3 0.3 35 4.6 0.0 2.9 3 0 0 3 3 3 0 Heavy-metal-associated domain Abhydrolase_6 PF12697.2 AJW70635.1 - 8.1e-37 127.2 0.0 9.2e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AJW70635.1 - 7.5e-21 74.7 0.0 7.9e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AJW70635.1 - 9.3e-18 64.3 0.0 1.5e-17 63.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AJW70635.1 - 3.9e-06 26.6 0.0 1.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 AJW70635.1 - 9.5e-05 21.9 0.0 0.36 10.2 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 AJW70635.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.13 AJW70635.1 - 0.0037 16.5 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Ser_hydrolase PF06821.8 AJW70635.1 - 0.02 14.4 0.0 0.65 9.5 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase Peptidase_S9 PF00326.16 AJW70635.1 - 0.05 12.8 0.0 7.2 5.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.15 AJW70635.1 - 0.058 12.8 0.0 0.14 11.5 0.0 1.7 3 0 0 3 3 3 0 Putative esterase Ndr PF03096.9 AJW70635.1 - 0.15 10.4 0.0 0.18 10.2 0.0 1.3 1 1 0 1 1 1 0 Ndr family Antitoxin-MazE PF04014.13 AJW70636.1 - 0.00085 18.9 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE MraZ PF02381.13 AJW70636.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 MraZ protein DDE_Tnp_ISL3 PF01610.12 AJW70637.1 - 0.026 14.0 1.7 0.035 13.6 1.2 1.2 1 0 0 1 1 1 0 Transposase DUF2937 PF11157.3 AJW70637.1 - 0.079 12.2 0.8 3.8 6.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Fib_alpha PF08702.5 AJW70637.1 - 0.26 11.4 5.9 1.1 9.4 4.1 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 AJW70637.1 - 0.34 11.0 4.8 0.92 9.7 0.3 2.3 1 1 1 2 2 2 0 Syntaxin Wx5_PLAF3D7 PF09688.5 AJW70637.1 - 0.61 10.0 5.2 0.31 10.9 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Duffy_binding PF05424.6 AJW70637.1 - 0.73 9.6 4.1 3.4 7.4 0.2 2.1 1 1 1 2 2 2 0 Duffy binding domain Sec8_exocyst PF04048.9 AJW70637.1 - 1.6 8.3 7.9 3.1 7.4 0.9 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain PhaC_N PF07167.8 AJW70638.1 - 4.2e-11 42.5 0.1 8.6e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.15 AJW70638.1 - 3.3e-10 39.9 0.0 4.5e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AJW70638.1 - 2.5e-08 34.1 0.0 3.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3141 PF11339.3 AJW70638.1 - 3.3e-08 32.3 0.0 5.4e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) Abhydrolase_5 PF12695.2 AJW70638.1 - 3.9e-07 29.9 0.0 2.2e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PHB_depo_C PF06850.6 AJW70638.1 - 0.00045 19.5 0.0 0.0029 16.8 0.0 2.2 1 1 1 2 2 2 1 PHB de-polymerase C-terminus DLH PF01738.13 AJW70638.1 - 0.0013 18.0 0.0 0.0055 16.0 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 AJW70638.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 AJW70638.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase PHA_synth_III_E PF09712.5 AJW70639.1 - 2e-09 37.2 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) IFP_35_N PF07334.8 AJW70639.1 - 0.026 14.5 7.3 0.58 10.1 1.2 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4200 PF13863.1 AJW70639.1 - 0.075 12.9 0.1 0.075 12.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) MutS_IV PF05190.13 AJW70639.1 - 0.21 11.7 4.6 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 MutS family domain IV CCDC-167 PF15188.1 AJW70639.1 - 0.24 11.3 2.5 0.54 10.2 0.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Laminin_II PF06009.7 AJW70639.1 - 0.26 11.0 2.6 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 Laminin Domain II Seryl_tRNA_N PF02403.17 AJW70639.1 - 0.76 9.8 8.7 2.5 8.1 1.2 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TFIIB PF00382.14 AJW70642.1 - 8.3e-35 118.4 6.0 1.7e-18 66.1 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW70642.1 - 5.8e-14 51.1 1.0 1.1e-13 50.2 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AJW70642.1 - 7.9e-05 22.2 0.3 0.0012 18.3 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain A2L_zn_ribbon PF08792.5 AJW70642.1 - 0.00017 20.9 1.9 0.00033 20.0 1.3 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 AJW70642.1 - 0.0003 19.8 3.1 0.00055 19.0 2.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Ribosomal_S27e PF01667.12 AJW70642.1 - 0.0026 17.2 1.6 0.006 16.1 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S27 RRN7 PF11781.3 AJW70642.1 - 0.011 15.2 0.4 0.024 14.1 0.3 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Lar_restr_allev PF14354.1 AJW70642.1 - 0.014 15.7 1.2 0.034 14.4 0.3 2.0 2 0 0 2 2 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 AJW70642.1 - 0.02 14.7 0.2 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4503 PF14951.1 AJW70642.1 - 0.024 12.8 0.2 0.038 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) TerY-C PF15616.1 AJW70642.1 - 0.024 14.5 0.7 0.053 13.4 0.5 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain DZR PF12773.2 AJW70642.1 - 0.027 14.2 0.4 0.058 13.2 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 AJW70642.1 - 0.03 13.9 0.2 0.071 12.7 0.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Peptidase_M13_N PF05649.8 AJW70642.1 - 0.074 12.0 1.7 0.43 9.5 0.8 2.3 2 1 0 2 2 2 0 Peptidase family M13 DUF2387 PF09526.5 AJW70642.1 - 0.097 12.6 0.1 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF3797 PF12677.2 AJW70642.1 - 0.99 9.0 4.0 4.3 7.0 2.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3797) zinc_ribbon_2 PF13240.1 AJW70642.1 - 1.5 8.4 8.5 14 5.3 5.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain TPR_11 PF13414.1 AJW70643.1 - 3.2e-14 52.3 0.1 3.1e-06 26.7 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AJW70643.1 - 1.4e-13 49.8 0.0 0.00064 19.2 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AJW70643.1 - 1e-10 40.6 0.0 0.00036 20.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_M10 PF00413.19 AJW70643.1 - 8e-10 38.6 0.1 1.9e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Matrixin TPR_16 PF13432.1 AJW70643.1 - 2e-06 28.2 0.0 0.0064 17.1 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJW70643.1 - 3.5e-06 27.1 0.0 0.55 11.0 0.0 3.7 1 1 3 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AJW70643.1 - 5.4e-06 25.8 0.9 0.35 10.7 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 AJW70643.1 - 1.2e-05 25.1 0.1 0.13 12.1 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Reprolysin_2 PF13574.1 AJW70643.1 - 2.9e-05 24.1 0.2 6.7e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AJW70643.1 - 4.3e-05 23.5 0.2 0.0001 22.2 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 TPR_19 PF14559.1 AJW70643.1 - 5.8e-05 23.3 0.0 0.32 11.3 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJW70643.1 - 6.1e-05 22.9 0.0 0.097 12.9 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 AJW70643.1 - 0.0001 21.8 0.0 0.21 11.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AJW70643.1 - 0.00043 20.5 0.2 0.7 10.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJW70643.1 - 0.00088 19.1 0.0 0.58 10.0 0.0 3.2 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Peptidase_M57 PF12388.3 AJW70643.1 - 0.0014 17.9 0.2 0.0044 16.3 0.2 1.6 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Apc3 PF12895.2 AJW70643.1 - 0.0055 16.8 0.2 0.42 10.7 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Reprolysin_3 PF13582.1 AJW70643.1 - 0.0094 16.4 0.1 0.0094 16.4 0.1 2.1 3 0 0 3 3 2 1 Metallo-peptidase family M12B Reprolysin-like TPR_9 PF13371.1 AJW70643.1 - 0.015 15.1 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M66 PF10462.4 AJW70643.1 - 0.023 13.5 0.0 0.053 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 AJW70643.1 - 0.029 13.9 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 AJW70643.1 - 0.041 13.6 0.2 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin PF01421.14 AJW70643.1 - 0.049 13.1 1.2 0.069 12.7 0.0 1.8 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease MIT PF04212.13 AJW70643.1 - 0.12 12.2 0.4 4.2 7.3 0.0 2.6 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain AATF-Che1 PF13339.1 AJW70644.1 - 0.00014 22.0 5.0 0.00026 21.1 3.5 1.5 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor DUF342 PF03961.8 AJW70644.1 - 0.025 13.0 4.0 0.029 12.7 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4037 PF13228.1 AJW70644.1 - 0.035 14.3 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) Med29 PF11568.3 AJW70644.1 - 0.049 13.6 0.5 0.06 13.4 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF948 PF06103.6 AJW70644.1 - 0.061 13.1 0.3 4.5 7.2 0.1 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cauli_DNA-bind PF03310.8 AJW70644.1 - 0.066 13.0 2.8 0.2 11.5 0.8 1.9 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Acetate_kinase PF00871.12 AJW70644.1 - 0.069 11.6 0.2 0.073 11.6 0.2 1.1 1 0 0 1 1 1 0 Acetokinase family FliD_N PF02465.13 AJW70644.1 - 0.12 12.7 3.0 1.9 8.8 0.1 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 AJW70644.1 - 0.14 11.7 1.5 0.18 11.3 1.1 1.2 1 0 0 1 1 1 0 IncA protein PRANC PF09372.5 AJW70644.1 - 0.14 12.1 2.6 0.98 9.4 0.0 2.1 1 1 1 2 2 2 0 PRANC domain Reo_sigmaC PF04582.7 AJW70644.1 - 0.16 11.1 0.9 0.25 10.4 0.6 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein COMP PF11598.3 AJW70644.1 - 0.17 11.9 0.4 10 6.2 0.0 2.9 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein DivIVA PF05103.8 AJW70644.1 - 0.23 11.4 3.6 0.75 9.8 1.8 1.7 1 1 0 1 1 1 0 DivIVA protein SNARE PF05739.14 AJW70644.1 - 0.35 10.5 1.7 4.4 7.0 0.5 2.2 2 0 0 2 2 2 0 SNARE domain BPL_LplA_LipB PF03099.14 AJW70645.1 - 9.3e-20 70.9 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.7 AJW70645.1 - 8.9e-15 54.0 0.2 2.9e-14 52.4 0.1 2.0 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.12 AJW70645.1 - 2.6e-10 39.7 1.5 5.1e-10 38.8 1.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain UPF0122 PF04297.9 AJW70645.1 - 0.011 15.7 1.1 0.041 13.8 0.0 2.3 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.1 AJW70645.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_34 PF13601.1 AJW70646.1 - 0.0001 22.2 0.6 0.00017 21.5 0.4 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_45 PF14947.1 AJW70646.1 - 0.00034 20.3 0.4 0.00064 19.4 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.14 AJW70646.1 - 0.00046 19.8 0.1 0.00078 19.0 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.1 AJW70646.1 - 0.00066 19.2 0.4 0.001 18.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) DUF2250 PF10007.4 AJW70646.1 - 0.00073 19.3 1.4 0.0011 18.7 0.7 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) TFIIE_alpha PF02002.12 AJW70646.1 - 0.0034 16.8 1.0 0.0053 16.2 0.7 1.4 1 1 0 1 1 1 1 TFIIE alpha subunit Rio2_N PF09202.6 AJW70646.1 - 0.0087 16.1 0.1 0.043 13.8 0.0 2.0 2 0 0 2 2 2 1 Rio2, N-terminal HTH_27 PF13463.1 AJW70646.1 - 0.02 15.2 0.2 0.058 13.7 0.2 1.8 1 1 0 1 1 1 0 Winged helix DNA-binding domain RB_A PF01858.12 AJW70646.1 - 0.023 14.3 0.3 0.96 9.0 0.0 2.0 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain z-alpha PF02295.12 AJW70646.1 - 0.041 13.6 0.2 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain A_deaminase_N PF08451.6 AJW70646.1 - 0.058 13.4 4.8 2.3 8.3 3.2 2.2 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Rrf2 PF02082.15 AJW70646.1 - 0.071 13.2 0.1 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Ribosomal_S19e PF01090.14 AJW70646.1 - 0.094 12.1 0.3 0.16 11.3 0.2 1.4 1 1 0 1 1 1 0 Ribosomal protein S19e AphA_like PF14557.1 AJW70646.1 - 0.094 12.2 0.1 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator FeoC PF09012.5 AJW70646.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF3782 PF12644.2 AJW70646.1 - 0.12 12.1 3.9 0.21 11.4 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) M16C_assoc PF08367.6 AJW70646.1 - 0.17 10.7 0.1 0.17 10.7 0.1 2.3 1 1 2 3 3 3 0 Peptidase M16C associated Spectrin PF00435.16 AJW70646.1 - 0.54 10.5 4.3 3.2 8.1 3.0 2.0 1 1 0 1 1 1 0 Spectrin repeat CoA_binding_2 PF13380.1 AJW70647.1 - 5.7e-36 123.2 0.1 6.6e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 AJW70647.1 - 5.8e-09 36.3 0.0 9.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_57 PF03065.10 AJW70647.1 - 0.02 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Pterin_4a PF01329.14 AJW70648.1 - 0.011 15.5 0.3 0.021 14.5 0.1 1.7 2 1 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase Syntaxin-6_N PF09177.6 AJW70648.1 - 0.047 14.1 1.6 0.18 12.2 0.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Pox_VLTF3 PF04947.9 AJW70648.1 - 0.054 13.0 1.8 0.82 9.1 0.3 2.0 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like MMR_HSR1_C PF08438.5 AJW70649.1 - 1.6e-32 111.9 0.0 3.4e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AJW70649.1 - 1.8e-15 56.8 0.0 5.1e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 AJW70649.1 - 1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 AJW70649.1 - 1.7e-05 24.1 0.0 0.00098 18.4 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AJW70649.1 - 0.00091 19.0 1.0 0.12 12.1 0.0 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 AJW70649.1 - 0.0059 16.0 0.6 2.9 7.2 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain zf-FCS PF06467.9 AJW70650.1 - 0.047 13.3 6.9 0.62 9.7 0.7 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC_4 PF14392.1 AJW70650.1 - 0.062 12.9 0.2 0.062 12.9 0.1 1.6 2 0 0 2 2 2 0 Zinc knuckle A2L_zn_ribbon PF08792.5 AJW70651.1 - 4.2e-05 22.8 3.5 6.3e-05 22.3 2.4 1.3 1 0 0 1 1 1 1 A2L zinc ribbon domain UPF0547 PF10571.4 AJW70651.1 - 0.003 17.2 1.4 0.55 9.9 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 DZR PF12773.2 AJW70651.1 - 0.03 14.1 0.4 0.05 13.4 0.3 1.4 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 AJW70651.1 - 0.032 13.9 0.3 0.04 13.6 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 AJW70651.1 - 0.1 12.2 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C4 PF00105.13 AJW70651.1 - 0.11 12.7 2.1 0.14 12.3 1.4 1.1 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) zf-C2H2 PF00096.21 AJW70651.1 - 0.26 11.6 0.5 0.26 11.6 0.4 1.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-dskA_traR PF01258.12 AJW70651.1 - 0.92 9.3 7.0 3 7.6 0.4 2.2 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_2 PF13240.1 AJW70651.1 - 1.2 8.7 4.0 61 3.2 0.1 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Polyketide_cyc PF03364.15 AJW70653.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport NAD_binding_8 PF13450.1 AJW70654.1 - 7e-13 48.3 0.1 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 AJW70654.1 - 1.1e-10 41.2 0.0 3.1e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 AJW70654.1 - 2.4e-08 33.2 0.0 0.002 17.1 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AJW70654.1 - 7.5e-05 21.7 0.8 0.0032 16.3 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AJW70654.1 - 0.0001 20.9 0.0 0.14 10.6 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 AJW70654.1 - 0.00028 20.0 0.3 0.00044 19.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AJW70654.1 - 0.0003 21.1 0.5 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 AJW70654.1 - 0.00039 18.8 1.0 0.006 14.9 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor Thi4 PF01946.12 AJW70654.1 - 0.011 14.8 0.7 0.019 14.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 AJW70654.1 - 0.018 13.9 1.9 0.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Strep_67kDa_ant PF06100.6 AJW70654.1 - 0.056 11.7 0.2 0.22 9.8 0.2 1.9 1 1 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family B12-binding PF02310.14 AJW70655.1 - 3e-13 49.6 0.0 4.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.12 AJW70655.1 - 6e-11 42.2 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain RNA_pol_Rpb6 PF01192.17 AJW70655.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb6 IPPT PF01715.12 AJW70655.1 - 0.075 12.0 0.1 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 IPP transferase ParG PF09274.5 AJW70656.1 - 0.11 12.3 0.1 1.9 8.4 0.0 2.4 1 1 2 3 3 3 0 ParG DICT PF10069.4 AJW70658.1 - 0.00043 19.8 0.0 0.0046 16.4 0.0 2.0 2 0 0 2 2 2 1 Sensory domain found in DIguanylate Cyclases & Two-component systems FAD_binding_7 PF03441.9 AJW70659.1 - 1.2e-89 300.2 0.5 1.7e-89 299.7 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 AJW70659.1 - 2.7e-38 131.2 0.0 4.7e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase MinC_C PF03775.11 AJW70660.1 - 0.056 13.0 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain NAD_binding_10 PF13460.1 AJW70662.1 - 9.3e-19 68.1 0.0 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AJW70662.1 - 7.9e-13 48.1 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 AJW70662.1 - 9.8e-11 41.5 0.0 9.7e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJW70662.1 - 6.5e-10 38.1 0.0 1.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJW70662.1 - 0.0057 15.5 0.0 0.016 14.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 AJW70662.1 - 0.011 14.6 0.1 0.045 12.6 0.0 2.0 3 0 0 3 3 3 0 Male sterility protein Polysacc_synt_2 PF02719.10 AJW70662.1 - 0.14 11.0 0.9 1.2 8.0 0.6 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2OG-FeII_Oxy_3 PF13640.1 AJW70665.1 - 3.7e-06 27.3 0.0 5.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily JmjC PF02373.17 AJW70665.1 - 0.014 15.5 0.1 0.071 13.3 0.0 2.0 2 0 0 2 2 2 0 JmjC domain, hydroxylase PhyH PF05721.8 AJW70665.1 - 0.036 14.0 0.0 0.077 13.0 0.0 1.5 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Peripla_BP_2 PF01497.13 AJW70666.1 - 4e-41 140.7 0.0 4.7e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Ribosomal_L17 PF01196.14 AJW70666.1 - 0.025 15.1 0.8 0.051 14.1 0.6 1.6 1 1 0 1 1 1 0 Ribosomal protein L17 Octopine_DH PF02317.12 AJW70666.1 - 0.051 13.2 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Methyltransf_31 PF13847.1 AJW70666.1 - 0.097 12.2 0.5 0.19 11.3 0.4 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF650 PF04894.7 AJW70667.1 - 4.3e-88 295.3 0.0 6e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF650) DUF651 PF04895.7 AJW70667.1 - 3.1e-35 120.1 0.0 4.9e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF651) HTH_7 PF02796.10 AJW70667.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF1722 PF08349.6 AJW70668.1 - 5e-33 113.4 2.2 7.6e-33 112.8 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF1002 PF06207.6 AJW70668.1 - 0.045 13.0 0.6 0.11 11.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) GDPD PF03009.12 AJW70668.1 - 0.095 12.1 0.3 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF2846 PF11008.3 AJW70669.1 - 0.095 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) DUF432 PF04254.8 AJW70671.1 - 2.8e-29 101.5 0.0 4.4e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF432) MS_channel PF00924.13 AJW70672.1 - 1.5e-47 161.6 0.4 2.3e-47 161.0 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Tetraspannin PF00335.15 AJW70672.1 - 5.9 6.0 9.1 10 5.3 6.3 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF2976 PF11190.3 AJW70672.1 - 9.2 5.8 7.4 0.4 10.2 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Lipoprotein_1 PF00820.14 AJW70674.1 - 0.024 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein Pyridox_oxidase PF01243.15 AJW70676.1 - 5.4e-07 29.5 0.0 7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AJW70676.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1449 PF07290.6 AJW70677.1 - 0.063 12.6 0.2 0.068 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) tRNA-synt_1e PF01406.14 AJW70678.1 - 1.4e-124 415.1 1.2 1.4e-124 415.1 0.8 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AJW70678.1 - 1.5e-12 46.8 1.1 3.6e-06 25.8 0.6 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 AJW70678.1 - 1.3e-11 44.5 1.5 3.4e-11 43.2 1.1 1.7 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.13 AJW70678.1 - 1.6e-07 30.3 0.1 0.0029 16.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.17 AJW70678.1 - 2.3e-06 25.9 0.0 8e-06 24.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DUF1447 PF07288.6 AJW70678.1 - 1.1 9.0 7.6 12 5.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1447) NAD_synthase PF02540.12 AJW70679.1 - 5.1e-78 261.3 0.3 5.9e-78 261.1 0.2 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 AJW70679.1 - 3e-05 22.7 0.0 0.00073 18.1 0.0 2.2 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 AJW70679.1 - 0.002 17.4 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 AJW70679.1 - 0.0025 17.3 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 AJW70679.1 - 0.006 16.0 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.9 AJW70679.1 - 0.013 14.9 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) eRF1_2 PF03464.10 AJW70679.1 - 0.045 14.0 0.1 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 eRF1 domain 2 Clostridium_P47 PF06597.6 AJW70679.1 - 0.058 11.8 0.1 0.098 11.1 0.1 1.3 1 0 0 1 1 1 0 Clostridium P-47 protein SpoIIID PF12116.3 AJW70679.1 - 0.08 12.8 0.2 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Stage III sporulation protein D HTH_23 PF13384.1 AJW70679.1 - 0.12 12.1 0.0 2.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 AJW70679.1 - 0.13 11.7 0.2 2.5 7.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-70, region 4 Rieske PF00355.21 AJW70681.1 - 2.1e-14 52.8 0.0 2.3e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AJW70681.1 - 1.3e-12 47.3 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain AdoHcyase_NAD PF00670.16 AJW70682.1 - 4.4e-52 176.1 1.0 4.4e-52 176.1 0.7 2.0 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 AJW70682.1 - 2.3e-49 167.7 0.3 2.9e-49 167.4 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 AJW70682.1 - 6.6e-10 38.4 0.8 1.1e-09 37.7 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AJW70682.1 - 5.9e-07 28.9 0.2 1.2e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 AJW70682.1 - 0.00041 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 AJW70682.1 - 0.0025 17.8 0.8 0.018 15.1 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 AJW70682.1 - 0.0032 17.1 1.3 0.017 14.7 0.2 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AJW70682.1 - 0.0041 17.5 0.1 0.0099 16.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 AJW70682.1 - 0.0057 16.0 0.3 0.013 14.8 0.2 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 AJW70682.1 - 0.025 14.1 0.1 0.065 12.7 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF364 PF04016.7 AJW70682.1 - 0.039 13.2 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Pyr_redox PF00070.22 AJW70682.1 - 0.22 11.9 0.2 0.22 11.9 0.1 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1g PF09334.6 AJW70683.1 - 1.4e-136 455.1 1.2 1.7e-136 454.9 0.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AJW70683.1 - 7.7e-21 73.7 0.6 1.7e-07 29.6 0.0 4.1 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AJW70683.1 - 2.5e-13 49.8 0.3 3.3e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 AJW70683.1 - 2.7e-08 33.6 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 AJW70683.1 - 2.5e-06 26.4 0.1 0.0012 17.6 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (K) FhuF PF06276.7 AJW70683.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter tRNA-synt_1d PF00750.14 AJW70683.1 - 0.038 12.8 0.3 0.88 8.3 0.0 2.6 2 1 1 3 3 3 0 tRNA synthetases class I (R) zf-ribbon_3 PF13248.1 AJW70683.1 - 0.36 10.1 6.9 17 4.8 4.8 2.4 1 1 0 1 1 1 0 zinc-ribbon domain DUF726 PF05277.7 AJW70684.1 - 1.8e-09 36.9 0.0 2.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.7 AJW70684.1 - 3.8e-08 32.9 0.0 6.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 AJW70684.1 - 7.5e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 AJW70684.1 - 0.00013 21.3 0.6 0.0054 16.0 0.4 2.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 AJW70684.1 - 0.00029 20.6 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 AJW70684.1 - 0.0029 17.2 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 AJW70684.1 - 0.003 17.3 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF1749 PF08538.5 AJW70684.1 - 0.0045 15.9 0.0 0.0065 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF2305 PF10230.4 AJW70684.1 - 0.0054 16.1 0.1 0.0097 15.3 0.1 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF2424 PF10340.4 AJW70684.1 - 0.067 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) PGAP1 PF07819.8 AJW70684.1 - 0.12 11.9 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.7 AJW70684.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase Guanylate_cyc PF00211.15 AJW70685.1 - 0.00058 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 AJW70686.1 - 2.7e-15 56.2 0.0 3.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fer4_2 PF12797.2 AJW70686.1 - 1.6 8.8 5.2 2.1 8.4 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Peptidase_M10 PF00413.19 AJW70689.1 - 1.2e-13 51.0 0.6 1.5e-13 50.7 0.4 1.1 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.1 AJW70689.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.19 AJW70689.1 - 0.1 11.9 0.7 13 5.1 0.1 2.4 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.1 AJW70690.1 - 0.00016 21.8 0.1 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 AJW70690.1 - 0.0011 18.4 0.5 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AJW70690.1 - 0.0013 18.7 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 AJW70690.1 - 0.0015 17.4 0.7 0.0029 16.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 AJW70690.1 - 0.0016 18.9 0.1 0.0036 17.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 AJW70690.1 - 0.002 17.5 0.1 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin PF01421.14 AJW70690.1 - 0.0086 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.19 AJW70690.1 - 0.035 13.8 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Matrixin Astacin PF01400.19 AJW70690.1 - 0.1 11.9 0.0 0.3 10.4 0.0 1.8 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) TBP PF00352.16 AJW70692.1 - 3.4e-58 192.9 0.2 3.1e-28 96.9 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AJW70692.1 - 8.9e-06 25.6 0.0 0.0099 15.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) TFIIB PF00382.14 AJW70693.1 - 8.7e-36 121.5 3.3 5.3e-19 67.7 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW70693.1 - 3.3e-11 42.3 0.5 5.7e-11 41.5 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 AJW70693.1 - 8.1e-06 25.7 0.0 0.05 13.5 0.0 2.9 3 0 0 3 3 3 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 AJW70693.1 - 0.00082 18.6 0.0 0.04 13.2 0.0 2.9 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.18 AJW70693.1 - 0.0021 17.6 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 AJW70693.1 - 0.0023 17.0 1.5 0.0059 15.7 1.0 1.7 1 1 0 1 1 1 1 zinc-ribbon domain Ribosomal_L37e PF01907.14 AJW70693.1 - 0.0027 17.4 0.2 0.006 16.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 AJW70693.1 - 0.015 15.1 0.4 0.034 13.9 0.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF294_C PF10335.4 AJW70693.1 - 0.017 14.7 0.1 3.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Sigma70_r4_2 PF08281.7 AJW70693.1 - 0.018 14.4 0.9 0.35 10.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 HypA PF01155.14 AJW70693.1 - 0.027 14.1 0.2 0.099 12.3 0.2 1.9 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family HTH_11 PF08279.7 AJW70693.1 - 0.032 13.8 1.7 0.61 9.7 0.0 3.0 3 0 0 3 3 3 0 HTH domain HTH_23 PF13384.1 AJW70693.1 - 0.083 12.5 0.1 2 8.2 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain LacI PF00356.16 AJW70693.1 - 0.12 11.9 0.4 50 3.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family zinc_ribbon_2 PF13240.1 AJW70693.1 - 0.22 11.0 5.5 3.8 7.1 3.8 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Peptidase_M13_N PF05649.8 AJW70693.1 - 0.74 8.7 3.8 1.1 8.2 0.5 2.2 2 1 0 2 2 2 0 Peptidase family M13 GTP_EFTU_D2 PF03144.20 AJW70694.1 - 1.7e-07 31.2 0.1 4.9e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AJW70694.1 - 0.0065 16.0 0.1 0.019 14.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 CTP_transf_2 PF01467.21 AJW70695.1 - 4.6e-13 49.5 0.0 6.1e-13 49.1 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase Citrate_ly_lig PF08218.6 AJW70695.1 - 0.002 17.5 0.0 0.12 11.8 0.0 2.2 1 1 1 2 2 2 2 Citrate lyase ligase C-terminal domain NTNH_C PF08470.5 AJW70695.1 - 0.049 13.2 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal HIGH_NTase1 PF05636.6 AJW70695.1 - 0.057 12.4 0.0 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase FAD_syn PF06574.7 AJW70695.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 1 0 1 1 1 0 FAD synthetase IlvN PF07991.7 AJW70696.1 - 1.9e-65 219.2 0.4 2.6e-65 218.8 0.3 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 AJW70696.1 - 3.4e-48 163.2 0.2 5.1e-48 162.6 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 AJW70696.1 - 8e-06 25.1 0.1 1.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 AJW70696.1 - 0.0011 18.8 0.3 0.0073 16.1 0.1 2.2 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AJW70696.1 - 0.0019 18.5 0.2 0.0038 17.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 AJW70696.1 - 0.007 16.2 0.3 0.014 15.2 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain B12-binding PF02310.14 AJW70697.1 - 2.9e-20 72.3 0.1 3.6e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 B12 binding domain Glyco_transf_28 PF03033.15 AJW70697.1 - 0.05 13.3 0.1 0.071 12.8 0.1 1.3 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DUF457 PF04307.9 AJW70697.1 - 0.056 12.7 0.1 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) PcrB PF01884.12 AJW70697.1 - 0.068 12.4 1.2 0.16 11.1 0.1 1.8 1 1 1 2 2 2 0 PcrB family IMPDH PF00478.20 AJW70697.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DnaJ_CXXCXGXG PF00684.14 AJW70698.1 - 0.034 14.2 9.9 0.12 12.3 6.9 1.9 1 1 0 1 1 1 0 DnaJ central domain Ribosomal_L33 PF00471.15 AJW70698.1 - 0.2 11.9 2.2 0.47 10.7 1.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L33 A2L_zn_ribbon PF08792.5 AJW70698.1 - 0.39 10.2 0.1 0.39 10.2 0.1 3.4 4 1 0 4 4 4 0 A2L zinc ribbon domain Fer4_3 PF12798.2 AJW70698.1 - 0.7 10.6 4.9 72 4.3 0.0 2.7 2 2 0 2 2 2 0 4Fe-4S binding domain Antifungal_prot PF11402.3 AJW70698.1 - 1.7 8.8 12.3 14 5.9 8.5 2.1 1 1 0 1 1 1 0 Antifungal protein zf-nanos PF05741.8 AJW70698.1 - 2 8.4 11.6 1.8 8.5 5.2 2.3 2 1 0 2 2 2 0 Nanos RNA binding domain DUF3268 PF11672.3 AJW70698.1 - 9.7 6.3 9.2 18 5.4 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) zinc_ribbon_6 PF14599.1 AJW70699.1 - 0.0016 18.1 2.4 0.0027 17.4 1.7 1.5 1 1 0 1 1 1 1 Zinc-ribbon Zn-ribbon_8 PF09723.5 AJW70699.1 - 0.11 12.5 6.2 0.14 12.0 4.3 1.2 1 0 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AJW70699.1 - 0.13 11.8 3.0 0.16 11.6 2.1 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 AJW70699.1 - 0.71 9.3 6.9 2.4 7.6 4.8 2.0 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-Paramyx-P PF13008.2 AJW70699.1 - 0.71 9.1 4.9 1.2 8.4 0.4 2.1 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein zf-trcl PF13451.1 AJW70699.1 - 8.7 6.0 9.0 7 6.3 1.7 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain Alba PF01918.16 AJW70700.1 - 1.2e-08 34.4 0.2 1.6e-08 33.9 0.2 1.2 1 0 0 1 1 1 1 Alba TFIIB PF00382.14 AJW70701.1 - 2.2e-33 113.8 5.6 7.2e-19 67.3 0.6 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW70701.1 - 1.7e-10 40.0 0.7 2.8e-10 39.3 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AJW70701.1 - 0.00013 21.5 0.4 0.01 15.3 0.1 2.1 1 1 0 2 2 2 1 Cyclin, N-terminal domain HTH_AsnC-type PF13404.1 AJW70701.1 - 0.00029 20.3 0.1 0.0094 15.4 0.0 2.7 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain zf-ribbon_3 PF13248.1 AJW70701.1 - 0.00078 18.5 0.5 0.0013 17.8 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain HTH_11 PF08279.7 AJW70701.1 - 0.0018 17.8 0.8 0.074 12.7 0.0 3.0 3 0 0 3 3 3 1 HTH domain HTH_Crp_2 PF13545.1 AJW70701.1 - 0.0038 16.9 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 AJW70701.1 - 0.0093 15.2 0.0 3.7 6.9 0.0 3.0 4 0 0 4 4 4 1 Sigma-70, region 4 A2L_zn_ribbon PF08792.5 AJW70701.1 - 0.015 14.7 1.4 0.015 14.7 1.0 1.6 2 0 0 2 2 1 0 A2L zinc ribbon domain HTH_3 PF01381.17 AJW70701.1 - 0.019 14.8 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix Cyclin_C PF02984.14 AJW70701.1 - 0.03 14.2 0.2 3.6 7.5 0.1 2.3 1 1 0 2 2 2 0 Cyclin, C-terminal domain HTH_24 PF13412.1 AJW70701.1 - 0.032 13.6 0.1 0.45 9.9 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding LacI PF00356.16 AJW70701.1 - 0.052 13.1 2.4 7.1 6.3 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Ribosomal_L37e PF01907.14 AJW70701.1 - 0.087 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e TetR_N PF00440.18 AJW70701.1 - 0.096 12.3 0.2 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Peptidase_M13_N PF05649.8 AJW70701.1 - 0.1 11.5 0.7 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Peptidase family M13 zinc_ribbon_2 PF13240.1 AJW70701.1 - 0.14 11.7 2.5 2 7.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HTH_23 PF13384.1 AJW70701.1 - 0.26 11.0 1.5 3.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain TrmB PF01978.14 AJW70702.1 - 0.00097 18.7 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FUR PF01475.14 AJW70702.1 - 0.0012 18.7 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_IclR PF09339.5 AJW70702.1 - 0.0029 17.1 0.0 0.0071 15.9 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain DDRGK PF09756.4 AJW70702.1 - 0.0035 16.7 0.4 0.0037 16.7 0.3 1.1 1 0 0 1 1 1 1 DDRGK domain HTH_20 PF12840.2 AJW70702.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AJW70702.1 - 0.011 15.0 0.1 0.024 14.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Hpr_kinase_N PF02603.11 AJW70702.1 - 0.036 13.7 0.3 0.052 13.2 0.2 1.2 1 0 0 1 1 1 0 HPr Serine kinase N terminus HXXSHH PF07586.6 AJW70703.1 - 0.0063 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) HicB PF05534.7 AJW70703.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 HicB family NinF PF05810.7 AJW70704.1 - 0.056 13.2 0.3 0.065 13.0 0.2 1.2 1 0 0 1 1 1 0 NinF protein zf-ribbon_3 PF13248.1 AJW70704.1 - 0.093 11.9 0.5 0.14 11.4 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-FCS PF06467.9 AJW70704.1 - 0.24 11.0 4.6 7.6 6.2 3.2 2.2 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Peptidase_M1 PF01433.15 AJW70705.1 - 8.1e-140 466.3 1.7 1.2e-139 465.8 1.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AJW70705.1 - 2.1e-60 204.7 0.1 4.7e-60 203.5 0.0 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AJW70705.1 - 5.8e-19 68.3 0.1 1.2e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_2 PF13646.1 AJW70705.1 - 0.025 14.8 0.0 0.08 13.2 0.0 1.9 1 1 0 1 1 1 0 HEAT repeats DUF2265 PF10023.4 AJW70705.1 - 0.043 12.9 0.7 0.11 11.6 0.1 1.9 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) SprT-like PF10263.4 AJW70705.1 - 0.073 12.7 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 SprT-like family ArgK PF03308.11 AJW70707.1 - 8.2e-73 244.4 6.3 1e-72 244.1 4.3 1.1 1 0 0 1 1 1 1 ArgK protein KAP_NTPase PF07693.9 AJW70707.1 - 1.3e-07 30.9 0.0 3.8e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 KAP family P-loop domain cobW PF02492.14 AJW70707.1 - 1.8e-07 30.7 0.5 4.5e-07 29.4 0.1 1.9 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 AJW70707.1 - 1.5e-05 24.6 0.4 0.0074 15.8 0.1 2.6 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 AJW70707.1 - 8.8e-05 22.2 1.2 0.0038 16.9 0.1 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 AJW70707.1 - 0.00012 21.0 3.4 0.0026 16.6 0.4 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 AJW70707.1 - 0.00048 19.6 0.2 0.0011 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 AJW70707.1 - 0.00064 18.9 0.1 0.0014 17.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 AJW70707.1 - 0.0027 17.4 3.7 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase RNA12 PF10443.4 AJW70707.1 - 0.0069 14.9 1.2 0.009 14.5 0.0 1.7 2 0 0 2 2 2 1 RNA12 protein Zeta_toxin PF06414.7 AJW70707.1 - 0.0076 15.3 0.3 0.018 14.1 0.2 1.7 1 0 0 1 1 1 1 Zeta toxin Ubiq_cyt_C_chap PF03981.7 AJW70707.1 - 0.01 15.7 0.4 0.02 14.7 0.3 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone AAA_16 PF13191.1 AJW70707.1 - 0.015 15.3 0.0 0.06 13.3 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 AJW70707.1 - 0.018 15.8 1.7 0.028 15.2 0.2 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AJW70707.1 - 0.03 14.2 2.1 0.11 12.5 1.4 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase IIGP PF05049.8 AJW70707.1 - 0.032 13.0 0.7 0.032 13.0 0.5 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NTPase_1 PF03266.10 AJW70707.1 - 0.034 13.8 0.6 0.13 11.9 0.2 2.1 1 1 0 1 1 1 0 NTPase Miro PF08477.8 AJW70707.1 - 0.04 14.3 1.5 0.13 12.7 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 AJW70707.1 - 0.042 13.9 0.5 0.24 11.5 0.1 2.3 1 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AJW70707.1 - 0.053 13.0 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AJW70707.1 - 0.058 12.6 1.9 0.076 12.2 0.1 2.1 2 1 0 2 2 2 0 PhoH-like protein AAA_35 PF14516.1 AJW70707.1 - 0.069 11.7 0.9 0.13 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 AJW70707.1 - 0.076 13.3 3.9 0.089 13.0 0.4 2.3 2 1 0 2 2 2 0 ABC transporter PRK PF00485.13 AJW70707.1 - 0.082 12.4 3.5 0.12 11.8 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF4238 PF14022.1 AJW70707.1 - 0.082 12.1 1.1 0.13 11.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) AAA_29 PF13555.1 AJW70707.1 - 0.13 11.8 0.3 0.26 10.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 AJW70707.1 - 0.16 12.2 2.4 0.39 11.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 AJW70707.1 - 0.44 10.8 11.7 1.7 8.9 0.7 2.7 2 1 0 2 2 2 0 AAA domain MM_CoA_mutase PF01642.17 AJW70708.1 - 7.3e-188 624.8 0.1 8.4e-188 624.6 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase PAP_PilO PF06864.7 AJW70708.1 - 0.0046 15.3 0.0 0.018 13.3 0.0 1.8 2 0 0 2 2 2 1 Pilin accessory protein (PilO) DUF2136 PF09907.4 AJW70708.1 - 0.049 13.7 1.3 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2136) Methyltransf_23 PF13489.1 AJW70709.1 - 0.00055 19.6 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW70709.1 - 0.012 16.1 0.0 0.038 14.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AJW70709.1 - 0.018 14.6 0.4 0.18 11.3 0.4 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 AJW70709.1 - 0.15 12.4 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PuR_N PF09182.5 AJW70710.1 - 0.15 11.7 0.2 0.18 11.4 0.1 1.3 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal Glyoxalase_4 PF13669.1 AJW70711.1 - 3.6e-23 81.6 0.0 4.3e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 AJW70711.1 - 1.5e-13 50.8 0.0 1.6e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AJW70711.1 - 9.6e-12 45.1 0.0 1e-11 45.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.2 AJW70711.1 - 8.6e-08 32.7 0.0 1e-07 32.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain YecM PF06185.7 AJW70711.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 YecM protein zf-CCHC PF00098.18 AJW70712.1 - 0.0071 16.2 2.8 0.083 12.8 0.1 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-C4_ClpX PF06689.8 AJW70712.1 - 0.019 14.4 0.5 0.019 14.4 0.4 2.5 2 1 0 2 2 2 0 ClpX C4-type zinc finger Zn-ribbon_8 PF09723.5 AJW70712.1 - 0.024 14.5 1.2 0.024 14.5 0.9 2.5 2 1 0 2 2 2 0 Zinc ribbon domain C1_3 PF07649.7 AJW70712.1 - 0.029 14.4 2.4 0.029 14.4 1.7 2.7 3 0 0 3 3 3 0 C1-like domain DUF2039 PF10217.4 AJW70712.1 - 0.049 13.6 11.6 0.11 12.5 4.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) LIM PF00412.17 AJW70712.1 - 0.061 13.4 9.0 0.47 10.5 1.0 2.8 1 1 2 3 3 3 0 LIM domain zinc_ribbon_2 PF13240.1 AJW70712.1 - 0.066 12.7 9.8 0.12 11.9 0.9 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.1 AJW70712.1 - 0.088 12.5 10.7 0.25 11.0 0.7 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Elf1 PF05129.8 AJW70712.1 - 0.14 11.8 11.7 0.09 12.4 1.4 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.2 AJW70712.1 - 0.15 11.8 9.8 7.6 6.4 6.8 2.5 1 1 0 1 1 1 0 Double zinc ribbon UPF0167 PF03691.9 AJW70712.1 - 0.18 11.2 7.2 0.054 12.9 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) C1_1 PF00130.17 AJW70712.1 - 0.18 11.5 11.3 1.6 8.4 1.3 3.1 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 AJW70712.1 - 0.44 10.2 10.5 0.48 10.1 3.8 2.7 2 1 1 3 3 3 0 PHD-finger zf-RING_2 PF13639.1 AJW70712.1 - 0.49 10.2 8.5 1.7 8.5 0.4 2.5 3 0 0 3 3 2 0 Ring finger domain zf-CHY PF05495.7 AJW70712.1 - 0.82 9.8 11.4 4.2 7.5 1.5 2.4 1 1 1 2 2 2 0 CHY zinc finger zf-CCHC_3 PF13917.1 AJW70712.1 - 0.85 9.4 5.0 1.5 8.6 0.0 3.0 3 0 0 3 3 3 0 Zinc knuckle NOB1_Zn_bind PF08772.6 AJW70712.1 - 1.1 9.1 8.2 0.31 10.9 2.9 2.1 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF2703 PF10865.3 AJW70712.1 - 1.2 9.1 4.9 0.37 10.7 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) FYVE PF01363.16 AJW70712.1 - 1.3 8.9 8.1 3.5 7.5 5.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-Mss51 PF13824.1 AJW70712.1 - 1.6 8.6 5.0 0.35 10.7 1.1 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2616 PF11077.3 AJW70712.1 - 1.8 8.0 6.9 3.2 7.2 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) zf-AD PF07776.10 AJW70712.1 - 2.7 8.0 9.1 2.2 8.3 0.6 2.8 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-ribbon_3 PF13248.1 AJW70712.1 - 3 7.1 9.0 3.6 6.9 2.1 2.7 2 1 0 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.4 AJW70712.1 - 3.6 7.4 11.1 6.1 6.6 0.2 3.7 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Cytochrom_c3_2 PF14537.1 AJW70712.1 - 7 7.0 8.9 19 5.7 0.6 2.0 1 1 1 2 2 2 0 Cytochrome c3 DUF4428 PF14471.1 AJW70712.1 - 9.1 6.1 15.6 0.26 11.0 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC4_3 PF13920.1 AJW70712.1 - 9.4 6.0 14.4 28 4.4 5.6 3.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CBS PF00571.23 AJW70713.1 - 1.1e-14 53.9 0.2 3.3e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 CBS domain HTH_3 PF01381.17 AJW70713.1 - 3e-14 52.5 0.3 5.5e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 AJW70713.1 - 2e-10 40.5 0.2 4.6e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 AJW70713.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 AJW70713.1 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 AJW70713.1 - 0.0099 16.0 0.2 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.1 AJW70713.1 - 0.011 15.4 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 AJW70713.1 - 0.065 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.1 AJW70713.1 - 0.12 11.8 0.1 0.3 10.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 AJW70713.1 - 0.12 11.7 0.2 0.25 10.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1059 PF06348.6 AJW70714.1 - 6.9e-19 67.4 0.4 7.2e-19 67.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) JmjC PF02373.17 AJW70714.1 - 0.059 13.6 0.1 0.062 13.5 0.1 1.0 1 0 0 1 1 1 0 JmjC domain, hydroxylase PUL PF08324.6 AJW70714.1 - 0.12 11.1 0.1 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 PUL domain PEP-utilizers_C PF02896.13 AJW70715.1 - 1.1e-90 303.5 0.3 2e-90 302.6 0.2 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 AJW70715.1 - 5.3e-58 196.6 0.0 2.2e-57 194.5 0.0 1.9 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 AJW70715.1 - 1.4e-21 75.7 0.1 4e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain TIM PF00121.13 AJW70716.1 - 4.7e-27 94.6 6.1 5.1e-25 87.9 4.3 2.0 1 1 0 1 1 1 1 Triosephosphate isomerase ThiG PF05690.9 AJW70716.1 - 6.9e-06 25.3 0.1 1.1e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 AJW70716.1 - 0.00032 19.8 0.1 0.00053 19.1 0.1 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.13 AJW70716.1 - 0.0013 17.6 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Synuclein PF01387.12 AJW70716.1 - 0.036 13.9 0.3 0.079 12.8 0.2 1.5 1 0 0 1 1 1 0 Synuclein His_biosynth PF00977.16 AJW70716.1 - 0.047 12.9 0.3 0.099 11.8 0.2 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 AJW70716.1 - 0.076 12.1 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase PcrB PF01884.12 AJW70716.1 - 0.11 11.7 4.2 0.067 12.4 0.5 2.1 2 1 1 3 3 3 0 PcrB family Flavodoxin_NdrI PF07972.6 AJW70716.1 - 0.12 12.2 0.0 9.6 6.1 0.0 2.3 2 0 0 2 2 2 0 NrdI Flavodoxin like Glu_synthase PF01645.12 AJW70716.1 - 0.6 8.9 4.4 0.7 8.7 1.2 2.2 2 1 0 2 2 2 0 Conserved region in glutamate synthase MtN3_slv PF03083.11 AJW70717.1 - 5.5e-09 35.7 3.1 6.2e-09 35.6 2.1 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 AJW70717.1 - 0.00043 19.7 3.1 0.00076 18.9 2.1 1.5 1 0 0 1 1 1 1 PQ loop repeat Zip PF02535.17 AJW70717.1 - 0.067 12.1 0.3 0.067 12.1 0.2 1.5 1 1 1 2 2 2 0 ZIP Zinc transporter LAB_N PF07578.6 AJW70717.1 - 0.088 12.7 2.8 0.11 12.4 1.9 1.2 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF3784 PF12650.2 AJW70717.1 - 1.1 9.3 9.4 3.4 7.6 6.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DNA_pol_B PF00136.16 AJW70718.1 - 3.8e-87 293.0 6.1 5.6e-87 292.4 4.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AJW70718.1 - 2.9e-44 151.2 6.3 5.1e-44 150.4 4.4 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 AJW70718.1 - 2.8e-07 30.4 1.5 8e-07 29.0 1.0 1.7 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 AJW70718.1 - 3.7e-06 26.6 0.7 1.2e-05 25.0 0.5 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Rep_fac-A_C PF08646.5 AJW70718.1 - 0.094 12.4 5.2 0.69 9.6 0.9 2.7 1 1 1 2 2 2 0 Replication factor-A C terminal domain dCMP_cyt_deam_1 PF00383.17 AJW70719.1 - 4.4e-26 90.5 1.3 5.6e-26 90.1 0.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FAM75 PF14650.1 AJW70720.1 - 0.043 13.2 1.6 0.044 13.1 1.1 1.0 1 0 0 1 1 1 0 FAM75 family BpuSI_N PF15516.1 AJW70720.1 - 0.062 12.9 0.4 0.071 12.8 0.3 1.0 1 0 0 1 1 1 0 BpuSI N-terminal domain DUF1154 PF06631.6 AJW70720.1 - 0.16 11.6 7.7 0.083 12.5 4.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1154) DUF4473 PF14747.1 AJW70720.1 - 0.31 11.2 3.8 0.33 11.1 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) DEAD PF00270.24 AJW70721.1 - 2.4e-19 69.4 0.0 9.9e-19 67.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AJW70721.1 - 1.1e-17 64.4 0.0 5.6e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AJW70721.1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Flavi_DEAD PF07652.9 AJW70721.1 - 0.007 16.1 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Flavivirus DEAD domain DUF1250 PF06855.7 AJW70722.1 - 0.12 11.8 0.7 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Spore_GerAC PF05504.6 AJW70722.1 - 0.26 11.0 4.8 1.2 8.8 1.2 2.0 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal SapB_1 PF05184.10 AJW70722.1 - 2.7 7.9 4.1 1.4 8.8 0.2 2.4 3 2 0 3 3 3 0 Saposin-like type B, region 1 Lipocalin PF00061.18 AJW70723.1 - 0.051 13.5 0.2 0.059 13.3 0.2 1.1 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family COX16 PF14138.1 AJW70723.1 - 0.068 13.3 0.9 0.077 13.1 0.6 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Rotamase_3 PF13616.1 AJW70724.1 - 9.8e-26 90.3 0.1 1.2e-25 90.0 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 AJW70724.1 - 1.1e-25 90.1 0.3 1.4e-25 89.8 0.2 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 AJW70724.1 - 2.8e-10 40.8 0.0 3.2e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain NTPase_I-T PF01931.13 AJW70724.1 - 0.025 14.2 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 EamA PF00892.15 AJW70726.1 - 1.7e-28 99.1 31.6 4.3e-15 55.8 4.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 AJW70726.1 - 2.4e-09 37.3 30.8 1.6e-06 28.2 1.8 3.3 1 1 3 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 AJW70726.1 - 1.6e-08 34.3 5.1 1.6e-08 34.3 3.5 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF914 PF06027.7 AJW70726.1 - 6.7e-06 25.1 20.6 1e-05 24.5 14.3 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 AJW70726.1 - 0.00024 20.1 3.9 0.00024 20.1 2.7 2.5 1 1 2 3 3 3 1 UAA transporter family Sugar_transport PF06800.7 AJW70726.1 - 0.0013 17.8 4.8 0.0013 17.8 3.3 2.3 1 1 1 2 2 2 2 Sugar transport protein UPF0546 PF10639.4 AJW70726.1 - 0.0018 18.1 0.4 0.0018 18.1 0.3 3.3 3 1 0 3 3 3 1 Uncharacterised protein family UPF0546 Acyl_transf_3 PF01757.17 AJW70726.1 - 0.0018 17.1 18.8 0.01 14.6 7.2 2.5 2 1 1 3 3 3 2 Acyltransferase family DUF2614 PF11023.3 AJW70726.1 - 0.025 14.3 1.0 0.025 14.3 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2614) HEAT_2 PF13646.1 AJW70727.1 - 9.6e-12 45.0 0.4 7.5e-10 38.9 0.2 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 AJW70727.1 - 7.4e-07 28.7 0.5 0.35 11.0 0.0 3.6 4 0 0 4 4 4 3 HEAT repeat DUF1129 PF06570.6 AJW70728.1 - 7.1 5.8 10.8 6 6.1 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) TrmB PF01978.14 AJW70729.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AJW70729.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Response_reg PF00072.19 AJW70730.1 - 5.1e-22 77.9 0.3 5.8e-22 77.8 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain AAA_14 PF13173.1 AJW70730.1 - 0.038 13.8 0.1 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain PASTA PF03793.14 AJW70730.1 - 0.076 12.6 0.4 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 PASTA domain FAD_binding_4 PF01565.18 AJW70730.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 FAD binding domain Pyridox_oxidase PF01243.15 AJW70731.1 - 1.5e-11 44.1 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AJW70731.1 - 5.3e-07 29.5 0.0 6.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PDDEXK_4 PF14281.1 AJW70731.1 - 0.049 13.4 0.4 0.051 13.4 0.3 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF447 PF04289.7 AJW70731.1 - 0.073 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) DUF2203 PF09969.4 AJW70733.1 - 2.8e-37 127.6 0.2 3.1e-37 127.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) Laminin_I PF06008.9 AJW70733.1 - 0.015 14.6 0.5 0.023 14.0 0.4 1.3 1 1 0 1 1 1 0 Laminin Domain I His_binding PF02098.11 AJW70733.1 - 0.044 13.6 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Tick histamine binding protein Bet_v_1 PF00407.14 AJW70733.1 - 0.067 12.8 0.2 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 Pathogenesis-related protein Bet v I family TrmB PF01978.14 AJW70734.1 - 2.2e-13 49.7 0.1 6.1e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AJW70734.1 - 5.3e-07 29.2 0.1 1.2e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.17 AJW70734.1 - 0.00012 21.6 0.2 0.00032 20.3 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.2 AJW70734.1 - 0.00017 21.3 0.1 0.00038 20.2 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain Regulator_TrmB PF11495.3 AJW70734.1 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_24 PF13412.1 AJW70734.1 - 0.0054 16.0 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HHH_5 PF14520.1 AJW70734.1 - 0.035 14.2 0.1 11 6.2 0.1 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain HTH_27 PF13463.1 AJW70734.1 - 0.052 13.8 0.1 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Lant_dehyd_C PF04738.8 AJW70734.1 - 0.078 11.1 0.2 0.1 10.8 0.1 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus HTH_11 PF08279.7 AJW70734.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.5 3 0 0 3 3 3 0 HTH domain DUF3618 PF12277.3 AJW70734.1 - 0.14 12.1 0.5 0.14 12.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF1515 PF07439.6 AJW70734.1 - 0.23 11.2 1.2 10 5.9 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) T2SF PF00482.18 AJW70735.1 - 1e-15 57.7 1.7 1.5e-15 57.1 0.2 2.0 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F DUF3671 PF12420.3 AJW70735.1 - 0.00036 20.4 4.7 0.017 15.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function DDE_Tnp_1_assoc PF13808.1 AJW70735.1 - 0.099 12.3 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-associated DUF1129 PF06570.6 AJW70735.1 - 0.23 10.7 3.6 0.52 9.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) T2SF PF00482.18 AJW70736.1 - 8.3e-14 51.5 0.3 8.3e-14 51.5 0.2 3.3 4 0 0 4 4 4 1 Type II secretion system (T2SS), protein F NfeD PF01957.13 AJW70736.1 - 1.2 9.2 14.3 0.14 12.2 0.7 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Zn-ribbon_8 PF09723.5 AJW70737.1 - 0.0063 16.4 4.6 2.2 8.3 0.2 3.8 3 0 0 3 3 3 2 Zinc ribbon domain zf-LYAR PF08790.6 AJW70737.1 - 0.082 12.6 1.1 0.23 11.2 0.8 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Cys_rich_KTR PF14205.1 AJW70737.1 - 0.77 9.2 5.9 0.48 9.9 0.3 3.2 3 0 0 3 3 3 0 Cysteine-rich KTR zinc_ribbon_5 PF13719.1 AJW70737.1 - 1.5 8.4 7.1 3.7 7.1 2.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJW70737.1 - 2.1 7.9 7.0 13 5.4 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJW70737.1 - 6.4 6.5 7.0 16 5.3 2.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Adenylsucc_synt PF00709.16 AJW70738.1 - 0.027 13.1 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Fe-ADH_2 PF13685.1 AJW70738.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase NPCBM_assoc PF10633.4 AJW70740.1 - 0.0077 16.2 3.0 3.3 7.8 0.0 4.2 4 0 0 4 4 4 1 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF11 PF01345.13 AJW70740.1 - 0.76 9.8 9.7 11 6.1 0.3 3.3 2 0 0 2 2 2 0 Domain of unknown function DUF11 CBM_15 PF03426.9 AJW70741.1 - 0.023 14.0 1.1 0.047 13.0 0.2 1.9 1 1 1 2 2 2 0 Carbohydrate binding domain (family 15) DUF1628 PF07790.6 AJW70742.1 - 5.4e-05 23.8 3.4 7.5e-05 23.4 1.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1628) DUF3899 PF13038.1 AJW70742.1 - 0.086 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Spore_YhaL PF14147.1 AJW70743.1 - 0.13 11.6 1.6 0.25 10.8 1.1 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL RecR PF02132.10 AJW70744.1 - 0.091 12.2 3.5 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 RecR protein zinc_ribbon_2 PF13240.1 AJW70744.1 - 0.37 10.3 0.1 0.37 10.3 0.1 1.9 3 0 0 3 3 3 0 zinc-ribbon domain UbiA PF01040.13 AJW70745.1 - 1.6e-30 106.2 18.3 2.1e-30 105.8 12.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Phage_holin_2 PF04550.7 AJW70745.1 - 0.092 12.8 0.1 0.092 12.8 0.1 3.5 4 0 0 4 4 4 0 Phage holin family 2 DUF2484 PF10658.4 AJW70745.1 - 0.32 11.1 8.1 5.1 7.2 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) RseC_MucC PF04246.7 AJW70745.1 - 9.7 5.7 16.3 0.99 8.9 2.3 3.7 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Aldo_ket_red PF00248.16 AJW70746.1 - 2.3e-30 105.3 0.0 3.6e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family DUF321 PF03778.8 AJW70746.1 - 0.16 11.4 1.1 0.38 10.2 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF321) YHS PF04945.8 AJW70749.1 - 1.9e-12 46.8 0.1 2.3e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 YHS domain ATPase-cat_bd PF12156.3 AJW70749.1 - 8e-05 23.0 0.2 0.0001 22.7 0.2 1.1 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Arc_trans_TRASH PF08394.5 AJW70749.1 - 0.00024 21.1 1.4 0.00035 20.6 1.0 1.3 1 0 0 1 1 1 1 Archaeal TRASH domain zf-FCS PF06467.9 AJW70749.1 - 0.01 15.4 0.8 0.013 15.1 0.5 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Ta0938 PF11494.3 AJW70749.1 - 0.073 13.1 0.2 0.073 13.1 0.1 1.1 1 0 0 1 1 1 0 Ta0938 CAP_GLY PF01302.20 AJW70749.1 - 0.15 11.7 0.3 0.26 10.9 0.2 1.5 1 1 0 1 1 1 0 CAP-Gly domain Asn_synthase PF00733.16 AJW70750.1 - 2.1e-35 122.4 0.0 3.7e-34 118.3 0.0 2.0 1 1 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJW70750.1 - 1.9e-05 24.0 0.1 6.2e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 AJW70750.1 - 1.9e-05 23.6 0.1 3.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 NAD synthase ThiI PF02568.9 AJW70750.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) DUF815 PF05673.8 AJW70750.1 - 0.0022 16.9 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) tRNA_Me_trans PF03054.11 AJW70750.1 - 0.0025 16.4 0.0 0.0058 15.2 0.0 1.6 1 1 0 1 1 1 1 tRNA methyl transferase ATP_bind_3 PF01171.15 AJW70750.1 - 0.0025 17.3 0.0 0.0057 16.1 0.0 1.5 1 1 0 1 1 1 1 PP-loop family DZR PF12773.2 AJW70750.1 - 0.0062 16.3 2.6 0.061 13.1 1.2 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AJW70750.1 - 0.0076 15.4 5.7 0.0076 15.4 4.0 1.9 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJW70750.1 - 0.0097 15.3 2.7 0.036 13.5 1.9 2.0 1 1 0 1 1 1 1 zinc-ribbon domain DUF3903 PF13043.1 AJW70750.1 - 0.15 11.5 0.5 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) Cript PF10235.4 AJW70750.1 - 0.49 10.7 4.5 0.73 10.2 0.3 2.7 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT HTH_19 PF12844.2 AJW70751.1 - 1.1e-05 25.4 0.3 0.00013 21.9 0.2 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 AJW70751.1 - 2.8e-05 23.8 0.0 6.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.1 AJW70751.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.7 AJW70751.1 - 0.028 14.0 1.2 0.077 12.6 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_26 PF13443.1 AJW70751.1 - 0.088 13.0 0.1 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.1 AJW70751.1 - 0.1 12.3 0.1 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain DUF134 PF02001.11 AJW70751.1 - 0.15 11.9 0.1 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF134 Alba PF01918.16 AJW70752.1 - 1.8e-09 37.0 0.3 2.2e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 Alba RNA_pol_Rpb6 PF01192.17 AJW70753.1 - 1.7e-13 50.0 1.1 3e-13 49.3 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb6 Leu_zip PF15294.1 AJW70753.1 - 0.02 13.9 0.2 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Leucine zipper YqzH PF14164.1 AJW70753.1 - 0.11 12.4 0.4 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 YqzH-like protein Cyclophil_like PF04126.8 AJW70754.1 - 9.9e-10 38.0 0.0 1.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like Ribosomal_S25 PF03297.10 AJW70755.1 - 0.00011 22.2 4.0 0.00012 22.1 2.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.14 AJW70755.1 - 0.0043 16.7 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.6 AJW70755.1 - 0.053 13.2 0.1 0.066 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) SID-1_RNA_chan PF13965.1 AJW70755.1 - 0.064 11.4 0.8 0.069 11.3 0.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ureide_permease PF07168.6 AJW70755.1 - 0.12 11.0 0.2 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Ureide permease DS PF01916.12 AJW70757.1 - 3.5e-55 187.2 0.0 4.1e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Rootletin PF15035.1 AJW70761.1 - 0.042 13.8 2.6 0.047 13.6 1.8 1.0 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ATG13 PF10033.4 AJW70761.1 - 0.094 12.1 1.1 0.095 12.1 0.8 1.1 1 0 0 1 1 1 0 Autophagy-related protein 13 DUF1640 PF07798.6 AJW70761.1 - 0.14 12.1 3.5 0.15 12.0 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4163 PF13739.1 AJW70761.1 - 4.2 8.2 6.6 5.4 7.8 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Enterotoxin_ST PF02048.11 AJW70761.1 - 6.4 7.1 5.8 5 7.4 2.3 1.9 1 1 1 2 2 2 0 Heat-stable enterotoxin ST zf-MIZ PF02891.15 AJW70762.1 - 0.012 15.0 1.1 0.62 9.6 0.8 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger tRNA-Thr_ED PF08915.6 AJW70765.1 - 1.9e-48 163.9 0.1 3.3e-48 163.1 0.1 1.4 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase tRNA-synt_2b PF00587.20 AJW70765.1 - 2.9e-26 92.1 2.1 3.6e-26 91.7 0.6 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AJW70765.1 - 4.7e-25 87.3 0.5 9.8e-25 86.3 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain Arginase PF00491.16 AJW70766.1 - 1.6e-67 227.7 0.1 1.9e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family DZR PF12773.2 AJW70767.1 - 0.0027 17.5 1.8 0.0031 17.2 1.2 1.1 1 0 0 1 1 1 1 Double zinc ribbon GCC2_GCC3 PF07699.8 AJW70767.1 - 0.0047 16.4 2.8 0.0069 15.9 1.9 1.3 1 0 0 1 1 1 1 GCC2 and GCC3 HypA PF01155.14 AJW70767.1 - 0.0056 16.3 1.0 0.0059 16.2 0.7 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Rep_fac-A_C PF08646.5 AJW70767.1 - 0.015 15.0 2.1 0.016 14.8 1.4 1.0 1 0 0 1 1 1 0 Replication factor-A C terminal domain OrfB_Zn_ribbon PF07282.6 AJW70767.1 - 0.023 14.3 1.5 0.028 14.0 1.1 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain NMD3 PF04981.8 AJW70767.1 - 0.024 13.7 2.0 0.027 13.6 1.4 1.0 1 0 0 1 1 1 0 NMD3 family zf-C4pol PF14260.1 AJW70767.1 - 0.035 14.1 1.3 0.04 13.9 0.9 1.1 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Integrin_B_tail PF07965.7 AJW70767.1 - 0.036 14.4 2.8 0.04 14.3 1.9 1.1 1 0 0 1 1 1 0 Integrin beta tail domain NinF PF05810.7 AJW70767.1 - 0.043 13.6 0.6 0.047 13.4 0.4 1.2 1 0 0 1 1 1 0 NinF protein TF_Zn_Ribbon PF08271.7 AJW70767.1 - 0.053 12.8 2.6 0.068 12.4 1.8 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Prok-RING_1 PF14446.1 AJW70767.1 - 0.055 13.2 3.1 0.078 12.7 2.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2197 PF09963.4 AJW70767.1 - 0.064 13.2 2.2 0.11 12.4 1.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) NOB1_Zn_bind PF08772.6 AJW70767.1 - 0.092 12.5 0.5 0.097 12.5 0.3 1.1 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 AJW70767.1 - 0.22 11.0 3.2 0.33 10.4 1.5 1.8 2 1 0 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.1 AJW70767.1 - 0.62 9.7 4.0 5.1 6.8 0.2 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain ADK_lid PF05191.9 AJW70767.1 - 1.2 8.8 3.8 2.6 7.7 2.6 1.6 1 1 1 2 2 2 0 Adenylate kinase, active site lid YhfH PF14149.1 AJW70767.1 - 1.3 8.8 6.5 6.6 6.6 1.2 2.2 2 0 0 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.5 AJW70767.1 - 2 8.4 6.4 11 6.1 4.5 1.9 1 1 1 2 2 2 0 Zinc ribbon domain CDP-OH_P_transf PF01066.16 AJW70768.1 - 5.4e-17 61.9 9.8 3e-16 59.5 6.7 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4131 PF13567.1 AJW70768.1 - 6.2 6.1 6.9 3.7 6.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_S26e PF01283.14 AJW70769.1 - 6.4e-34 116.6 1.2 6.9e-34 116.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PHD PF00628.24 AJW70769.1 - 0.06 13.0 0.2 9.4 6.0 0.0 2.3 2 0 0 2 2 2 0 PHD-finger zf-ribbon_3 PF13248.1 AJW70769.1 - 0.066 12.4 0.3 0.066 12.4 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF3279 PF11682.3 AJW70769.1 - 0.14 11.7 1.4 0.68 9.5 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) zinc_ribbon_5 PF13719.1 AJW70769.1 - 0.15 11.6 2.4 0.4 10.3 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 AJW70769.1 - 0.15 11.7 0.7 0.99 9.1 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.1 AJW70769.1 - 0.15 11.7 2.1 0.42 10.3 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TrmB PF01978.14 AJW70770.1 - 4.9e-10 38.9 0.0 1.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 AJW70770.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.17 AJW70770.1 - 0.0056 16.3 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 MarR family TFIIE_alpha PF02002.12 AJW70770.1 - 0.0066 15.9 0.7 0.035 13.6 0.5 2.2 1 1 0 1 1 1 1 TFIIE alpha subunit HTH_27 PF13463.1 AJW70770.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.7 AJW70770.1 - 0.066 13.0 0.2 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC PfkB PF00294.19 AJW70772.1 - 6.5e-10 38.6 0.0 2.4e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AJW70772.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase tRNA_m1G_MT PF01746.16 AJW70772.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase NOB1_Zn_bind PF08772.6 AJW70772.1 - 0.16 11.8 3.8 0.3 10.9 1.5 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like YABBY PF04690.8 AJW70774.1 - 0.0077 16.4 0.4 0.012 15.8 0.3 1.3 1 0 0 1 1 1 1 YABBY protein zf-BED PF02892.10 AJW70774.1 - 0.012 15.3 0.4 0.024 14.3 0.3 1.6 1 0 0 1 1 1 0 BED zinc finger GPS PF01825.16 AJW70774.1 - 0.055 13.5 4.1 0.16 12.0 2.8 1.8 1 1 0 1 1 1 0 Latrophilin/CL-1-like GPS domain DUF3742 PF12553.3 AJW70775.1 - 0.0023 18.3 0.0 0.0063 16.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3742) DUF1312 PF07009.6 AJW70775.1 - 0.071 12.9 0.6 0.085 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) DUF3955 PF13127.1 AJW70775.1 - 0.082 12.4 1.8 0.11 11.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) DUF929 PF06053.6 AJW70775.1 - 0.094 11.7 0.3 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) tRNA_anti-like PF12869.2 AJW70775.1 - 0.095 12.1 0.1 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA_anti-like OppC_N PF12911.2 AJW70775.1 - 0.2 11.0 1.0 0.3 10.4 0.7 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF515 PF04415.7 AJW70775.1 - 0.22 9.7 1.6 0.23 9.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EzrA PF06160.7 AJW70775.1 - 0.33 9.0 1.3 0.37 8.9 0.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NAD_kinase PF01513.16 AJW70776.1 - 3.4e-32 111.3 0.2 6.7e-32 110.4 0.1 1.4 1 1 0 1 1 1 1 ATP-NAD kinase TrmB PF01978.14 AJW70776.1 - 1.1e-05 25.0 0.8 0.0011 18.6 0.2 2.9 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 AJW70776.1 - 3e-05 23.6 0.6 6.5e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 AJW70776.1 - 0.00017 20.9 0.6 0.00078 18.7 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 AJW70776.1 - 0.00021 21.5 0.3 0.00045 20.4 0.2 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain RNA_pol_Rpc34 PF05158.7 AJW70776.1 - 0.00028 20.1 0.4 0.00041 19.6 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.2 AJW70776.1 - 0.00063 19.3 0.1 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 MarR family FeoC PF09012.5 AJW70776.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator TFIIE_alpha PF02002.12 AJW70776.1 - 0.11 12.0 1.0 0.36 10.3 0.3 2.2 2 1 1 3 3 3 0 TFIIE alpha subunit CTP_synth_N PF06418.9 AJW70777.1 - 1.2e-121 405.0 0.2 1.9e-121 404.3 0.1 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AJW70777.1 - 2.2e-50 170.8 0.0 3.9e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJW70777.1 - 4.5e-12 45.8 0.0 3.4e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 AJW70777.1 - 8.7e-07 28.5 0.1 1.4e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Copper-bind PF00127.15 AJW70778.1 - 0.00013 22.1 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Class_IIIsignal PF04021.7 AJW70778.1 - 0.35 10.6 1.9 0.83 9.4 1.3 1.7 1 0 0 1 1 1 0 Class III signal peptide DUF2273 PF10031.4 AJW70778.1 - 0.74 9.4 3.0 1.6 8.3 2.1 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Trp_syntA PF00290.15 AJW70779.1 - 1.3e-84 282.7 0.8 1.6e-84 282.5 0.6 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain DHO_dh PF01180.16 AJW70779.1 - 1e-08 34.5 0.4 1.4e-08 34.0 0.3 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 AJW70779.1 - 1.1e-07 31.3 0.2 4e-07 29.5 0.1 1.9 3 0 0 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.13 AJW70779.1 - 1e-05 24.6 0.0 5.2e-05 22.2 0.0 2.0 1 1 1 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.12 AJW70779.1 - 8.6e-05 21.8 0.7 0.00015 21.0 0.2 1.8 2 0 0 2 2 2 1 PcrB family IMPDH PF00478.20 AJW70779.1 - 0.00038 19.4 1.1 0.00093 18.1 0.4 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 AJW70779.1 - 0.0017 17.4 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG BtpA PF03437.10 AJW70779.1 - 0.0056 15.9 0.7 0.69 9.1 0.6 2.2 1 1 1 2 2 2 1 BtpA family IGPS PF00218.16 AJW70779.1 - 0.0058 15.7 0.0 0.13 11.2 0.0 2.2 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 AJW70779.1 - 0.0087 15.0 0.3 0.023 13.6 0.1 1.9 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NIF3 PF01784.13 AJW70779.1 - 0.044 13.3 0.6 4.9 6.6 0.0 2.2 1 1 0 2 2 2 0 NIF3 (NGG1p interacting factor 3) TMP-TENI PF02581.12 AJW70779.1 - 0.044 12.8 0.6 0.092 11.8 0.3 1.9 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI TGT PF01702.13 AJW70779.1 - 0.078 12.2 0.0 0.33 10.1 0.0 2.0 2 1 0 2 2 2 0 Queuine tRNA-ribosyltransferase Ribul_P_3_epim PF00834.14 AJW70779.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PALP PF00291.20 AJW70780.1 - 4.8e-44 150.8 1.6 6.4e-44 150.4 1.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IGPS PF00218.16 AJW70781.1 - 4.6e-72 242.1 2.1 5.5e-72 241.8 1.4 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.14 AJW70781.1 - 1.4e-07 31.1 0.2 3.7e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 AJW70781.1 - 2.2e-05 23.5 0.9 5.1e-05 22.3 0.2 2.0 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 AJW70781.1 - 3.7e-05 22.7 0.0 0.00021 20.2 0.0 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DUF556 PF04476.8 AJW70781.1 - 0.0013 18.0 0.3 0.0079 15.4 0.1 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF556) His_biosynth PF00977.16 AJW70781.1 - 0.0013 18.0 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein AP_endonuc_2 PF01261.19 AJW70781.1 - 0.0058 15.9 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PcrB PF01884.12 AJW70781.1 - 0.016 14.4 0.1 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 PcrB family Glyco_hydro_97 PF10566.4 AJW70781.1 - 0.059 12.4 0.1 0.097 11.7 0.1 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 EAL PF00563.15 AJW70781.1 - 0.067 12.6 0.1 2.3 7.6 0.0 2.3 1 1 1 2 2 2 0 EAL domain Cellulase PF00150.13 AJW70781.1 - 0.079 12.1 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glycos_transf_3 PF00591.16 AJW70782.1 - 3.3e-79 265.8 0.5 5.5e-79 265.1 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 AJW70782.1 - 2.7e-15 55.7 0.7 5.1e-15 54.8 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain MCPsignal PF00015.16 AJW70782.1 - 0.27 10.7 2.9 7.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Orthopox_A49R PF06489.6 AJW70783.1 - 0.069 13.1 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Orthopoxvirus A49R protein GATase PF00117.23 AJW70784.1 - 1.6e-57 194.0 0.3 1.8e-57 193.8 0.2 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJW70784.1 - 2e-10 40.4 0.1 3.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 SNO PF01174.14 AJW70784.1 - 0.0001 21.9 0.2 0.00025 20.7 0.1 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family HTS PF04204.11 AJW70784.1 - 0.082 11.6 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Homoserine O-succinyltransferase Chorismate_bind PF00425.13 AJW70785.1 - 4.1e-91 304.8 0.0 2e-90 302.6 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 AJW70785.1 - 5.2e-23 81.5 0.2 6.1e-20 71.6 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region zf-HC5HC2H PF13771.1 AJW70786.1 - 0.036 14.2 1.6 0.039 14.0 0.9 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain Rad50_zn_hook PF04423.9 AJW70786.1 - 0.05 13.0 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif HATPase_c PF02518.21 AJW70788.1 - 1.5e-18 66.4 0.0 3.9e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.20 AJW70788.1 - 8.4e-13 48.3 0.4 1.1e-11 44.6 0.0 2.6 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.1 AJW70788.1 - 1.6e-10 40.5 0.8 5.6e-10 38.8 0.1 2.3 2 0 0 2 2 2 1 GHKL domain HisKA PF00512.20 AJW70788.1 - 2.4e-10 40.2 0.0 7.3e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Cluap1 PF10234.4 AJW70788.1 - 0.00059 19.1 1.3 0.0014 17.9 0.9 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF948 PF06103.6 AJW70788.1 - 0.0043 16.8 6.5 0.34 10.8 0.2 3.7 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF948) IncA PF04156.9 AJW70788.1 - 0.12 11.9 0.1 0.12 11.9 0.0 2.7 2 1 0 2 2 2 0 IncA protein DUF2120 PF09893.4 AJW70788.1 - 0.36 10.7 5.8 1 9.2 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1469 PF07332.6 AJW70788.1 - 0.85 9.3 4.1 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Response_reg PF00072.19 AJW70789.1 - 2.6e-20 72.4 0.3 2.9e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.6 AJW70789.1 - 0.011 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ DNA_gyraseA_C PF03989.8 AJW70790.1 - 0.0099 15.1 0.2 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase C-terminal domain, beta-propeller Gly_acyl_tr_C PF08444.5 AJW70790.1 - 0.12 12.3 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Sigma70_r4_2 PF08281.7 AJW70794.1 - 0.0084 15.5 0.1 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 AJW70794.1 - 0.048 13.0 0.3 0.11 11.9 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 AJW70794.1 - 0.065 12.9 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.1 AJW70794.1 - 0.08 12.7 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TBPIP PF07106.8 AJW70795.1 - 0.00034 20.1 8.2 0.0042 16.6 1.3 2.5 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 AJW70795.1 - 0.0033 16.4 2.5 0.73 8.7 0.2 2.5 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 CorA PF01544.13 AJW70795.1 - 0.004 16.2 0.7 0.25 10.3 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Lzipper-MIP1 PF14389.1 AJW70795.1 - 0.0044 17.0 5.4 4.5 7.4 0.0 3.8 3 1 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 FlxA PF14282.1 AJW70795.1 - 0.0087 16.0 9.2 0.12 12.3 1.1 2.9 2 0 0 2 2 2 2 FlxA-like protein IL3 PF02059.10 AJW70795.1 - 0.0088 16.0 0.4 0.34 10.9 0.0 2.6 2 0 0 2 2 2 1 Interleukin-3 IncA PF04156.9 AJW70795.1 - 0.01 15.4 8.2 0.39 10.2 0.2 2.8 3 0 0 3 3 3 0 IncA protein bZIP_1 PF00170.16 AJW70795.1 - 0.025 14.5 1.0 1.2 9.1 0.2 2.8 2 0 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 AJW70795.1 - 0.033 14.5 6.7 0.065 13.5 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF972) Med9 PF07544.8 AJW70795.1 - 0.062 13.0 4.1 1.2 8.9 0.1 2.9 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF603 PF04645.7 AJW70795.1 - 0.097 12.6 1.8 1 9.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF603 gpW PF02831.10 AJW70795.1 - 0.12 11.8 0.4 7.5 6.1 0.0 2.7 3 0 0 3 3 2 0 gpW Curto_V3 PF07436.6 AJW70795.1 - 0.13 12.4 2.3 9.6 6.4 0.0 2.9 3 0 0 3 3 2 0 Curtovirus V3 protein NPV_P10 PF05531.7 AJW70795.1 - 0.13 12.4 7.3 1.6 9.0 1.8 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.13 AJW70795.1 - 0.15 11.5 4.3 3.6 7.0 0.3 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 AJW70795.1 - 0.19 11.5 7.4 1.3 8.8 0.8 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 AJW70795.1 - 0.21 10.9 4.8 1.1 8.7 0.4 2.2 2 0 0 2 2 2 0 Intermediate filament protein Shugoshin_N PF07558.6 AJW70795.1 - 0.3 10.8 7.4 0.2 11.4 0.2 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Seryl_tRNA_N PF02403.17 AJW70795.1 - 0.32 11.0 12.3 4.4 7.3 2.2 3.9 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 AJW70795.1 - 0.48 10.2 4.8 11 5.7 0.5 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF848 PF05852.6 AJW70795.1 - 0.53 10.1 5.4 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Swi5 PF07061.6 AJW70795.1 - 0.67 9.7 4.4 0.4 10.4 0.6 2.4 3 0 0 3 3 3 0 Swi5 Ax_dynein_light PF10211.4 AJW70795.1 - 0.85 9.4 5.0 0.76 9.5 0.7 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Vps51 PF08700.6 AJW70795.1 - 1.1 9.1 4.6 1.9 8.3 0.2 3.1 3 0 0 3 3 2 0 Vps51/Vps67 Microtub_assoc PF07989.6 AJW70795.1 - 1.2 9.0 5.1 1.3 8.8 0.5 2.8 3 0 0 3 3 3 0 Microtubule associated AKNA PF12443.3 AJW70795.1 - 2.5 8.1 5.9 0.66 10.0 0.1 2.8 3 1 1 4 4 4 0 AT-hook-containing transcription factor FlaC_arch PF05377.6 AJW70795.1 - 2.8 7.9 11.3 5.7 6.9 2.4 3.6 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 AJW70795.1 - 3.5 7.3 12.3 0.78 9.4 1.0 3.2 3 2 0 3 3 2 0 Spc24 subunit of Ndc80 HR1 PF02185.11 AJW70795.1 - 6.6 6.5 12.3 0.83 9.4 0.1 3.7 4 0 0 4 4 3 0 Hr1 repeat CorA PF01544.13 AJW70796.1 - 9.2e-70 234.9 8.3 9.2e-70 234.9 5.7 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Herpes_UL92 PF03048.9 AJW70796.1 - 0.091 12.3 3.9 0.056 13.0 0.5 2.2 1 1 1 2 2 2 0 UL92 family DUF3311 PF11755.3 AJW70796.1 - 1 8.9 7.2 0.74 9.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Ion_trans PF00520.26 AJW70797.1 - 6.9e-21 74.4 9.4 6.9e-21 74.4 6.5 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 AJW70797.1 - 4.9e-13 48.6 4.9 4.9e-13 48.6 3.4 2.2 3 0 0 3 3 3 1 Ion channel zinc_ribbon_2 PF13240.1 AJW70797.1 - 0.05 13.1 0.4 0.081 12.4 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain PKD_channel PF08016.7 AJW70797.1 - 0.098 11.0 3.3 0.16 10.3 2.3 1.6 1 1 0 1 1 1 0 Polycystin cation channel Tetraspannin PF00335.15 AJW70797.1 - 3.6 6.8 5.3 17 4.5 0.8 2.7 2 1 0 2 2 2 0 Tetraspanin family IncA PF04156.9 AJW70798.1 - 0.00051 19.6 0.6 0.001 18.6 0.4 1.5 1 0 0 1 1 1 1 IncA protein DUF2678 PF10856.3 AJW70798.1 - 0.032 13.9 7.1 0.047 13.4 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF1664 PF07889.7 AJW70798.1 - 2.7 7.8 8.3 0.068 12.9 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TP53IP5 PF15331.1 AJW70799.1 - 0.12 12.3 5.1 0.16 11.8 3.5 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Ycf1 PF05758.7 AJW70800.1 - 0.0072 14.1 0.4 0.0086 13.8 0.3 1.1 1 0 0 1 1 1 1 Ycf1 DUF3748 PF12566.3 AJW70800.1 - 0.019 14.8 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3748) PD40 PF07676.7 AJW70800.1 - 0.052 13.2 0.3 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ATP-synt_E PF05680.7 AJW70800.1 - 0.089 12.7 4.0 0.16 11.9 2.8 1.3 1 0 0 1 1 1 0 ATP synthase E chain DUF2116 PF09889.4 AJW70802.1 - 0.0015 18.2 1.5 0.0019 17.9 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ecl1 PF12855.2 AJW70802.1 - 0.04 13.2 7.3 0.064 12.5 5.1 1.6 1 1 0 1 1 1 0 Life-span regulatory factor DZR PF12773.2 AJW70802.1 - 0.049 13.4 0.7 0.058 13.2 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AJW70802.1 - 0.11 11.7 0.4 0.15 11.2 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-MYND PF01753.13 AJW70802.1 - 0.13 12.1 3.7 0.16 11.8 2.6 1.3 1 1 0 1 1 1 0 MYND finger Acetyltransf_1 PF00583.19 AJW70804.1 - 1.8e-08 34.3 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AJW70804.1 - 3.7e-06 26.8 0.0 0.029 14.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AJW70804.1 - 0.0047 17.0 0.0 0.037 14.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Amidohydro_2 PF04909.9 AJW70805.1 - 2.5e-31 109.2 0.0 3.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 AJW70805.1 - 3.8e-05 23.0 0.0 5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_5 PF13594.1 AJW70805.1 - 0.13 12.1 0.1 6.2 6.7 0.0 2.5 2 1 0 2 2 2 0 Amidohydrolase FGase PF05013.7 AJW70807.1 - 7e-39 134.0 0.0 8.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase Na_H_Exchanger PF00999.16 AJW70808.1 - 1.6e-64 217.8 50.2 1.6e-64 217.8 34.8 2.3 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family SHOCT PF09851.4 AJW70809.1 - 3e-06 26.4 4.6 7.2e-06 25.2 3.2 1.7 1 1 0 1 1 1 1 Short C-terminal domain RNA_pol_A_CTD PF03118.10 AJW70809.1 - 0.04 13.3 0.6 0.11 11.8 0.4 1.8 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain GvpG PF05120.7 AJW70809.1 - 0.087 12.6 0.2 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Gas vesicle protein G CCDC32 PF14989.1 AJW70809.1 - 0.38 10.5 3.3 0.63 9.8 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 SMAP PF15477.1 AJW70809.1 - 0.47 10.7 2.5 0.41 10.9 0.5 1.8 2 0 0 2 2 2 0 Small acidic protein family DUF2484 PF10658.4 AJW70810.1 - 0.03 14.4 1.9 0.033 14.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) SHR3_chaperone PF08229.6 AJW70810.1 - 0.21 10.4 1.1 0.28 10.1 0.8 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 2TM PF13239.1 AJW70810.1 - 0.38 10.8 5.4 0.43 10.6 3.7 1.1 1 0 0 1 1 1 0 2TM domain LHC PF00556.15 AJW70810.1 - 6 6.8 6.4 0.43 10.4 0.9 1.7 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit ETRAMP PF09716.5 AJW70810.1 - 9.6 6.2 6.2 1.4 8.8 1.4 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PRC PF05239.11 AJW70811.1 - 9e-16 57.5 2.3 9.2e-07 28.6 0.8 2.1 2 0 0 2 2 2 2 PRC-barrel domain MCE PF02470.15 AJW70811.1 - 0.0007 19.5 0.5 0.032 14.2 0.2 2.2 1 1 1 2 2 2 1 mce related protein Tricorn_PDZ PF14685.1 AJW70811.1 - 0.0061 16.3 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain GTP_EFTU_D4 PF14578.1 AJW70811.1 - 0.015 14.9 0.9 0.14 11.7 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu domain 4 RNA_pol_Rpb2_6 PF00562.23 AJW70811.1 - 0.029 13.1 0.3 0.043 12.5 0.2 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 6 FerB PF08150.7 AJW70811.1 - 0.14 12.2 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 FerB (NUC096) domain AsnC_trans_reg PF01037.16 AJW70812.1 - 2.9e-10 39.7 0.0 3.3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 AJW70812.1 - 0.022 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 ACT domain Na_H_Exchanger PF00999.16 AJW70814.1 - 4.5e-59 199.8 52.0 5.9e-59 199.5 36.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CBS PF00571.23 AJW70814.1 - 2.8e-13 49.4 1.1 1.4e-09 37.5 0.1 2.7 2 0 0 2 2 2 2 CBS domain Acetyltransf_4 PF13420.1 AJW70814.1 - 0.004 17.1 0.4 0.0099 15.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SDF PF00375.13 AJW70815.1 - 6e-114 380.8 47.1 6.8e-114 380.6 32.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CDC24 PF06395.6 AJW70815.1 - 0.067 13.2 0.2 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 CDC24 Calponin Ion_trans_2 PF07885.11 AJW70816.1 - 2.1e-16 59.4 9.3 4e-16 58.5 6.4 1.5 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 AJW70816.1 - 9e-06 25.0 2.9 1.2e-05 24.6 2.0 1.2 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.21 AJW70816.1 - 1.3e-05 24.9 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel IRK PF01007.15 AJW70816.1 - 0.0041 15.9 0.1 0.0051 15.6 0.1 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel Flavi_NS2B PF01002.14 AJW70816.1 - 0.0096 15.5 0.4 0.022 14.3 0.3 1.6 1 0 0 1 1 1 1 Flavivirus non-structural protein NS2B CD20 PF04103.10 AJW70816.1 - 0.078 12.9 4.1 0.12 12.3 2.7 1.3 1 1 0 1 1 1 0 CD20-like family PetG PF02529.10 AJW70816.1 - 2.5 7.6 5.3 4.3 6.9 2.8 2.0 1 1 1 2 2 2 0 Cytochrome B6-F complex subunit 5 Usp PF00582.21 AJW70817.1 - 2.8e-30 105.3 0.0 3.3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Phage_Treg PF04761.7 AJW70817.1 - 0.011 15.4 0.5 3.6 7.4 0.0 2.4 1 1 1 2 2 2 0 Lactococcus bacteriophage putative transcription regulator NAD_binding_1 PF00175.16 AJW70817.1 - 0.019 15.5 0.1 0.038 14.5 0.1 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Bul1_C PF04426.7 AJW70817.1 - 0.021 14.0 1.6 0.027 13.6 1.1 1.2 1 0 0 1 1 1 0 Bul1 C terminus DUF4613 PF15390.1 AJW70817.1 - 0.024 12.8 0.0 0.027 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF21 PF01595.15 AJW70818.1 - 3.2e-47 160.1 0.4 4.2e-47 159.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AJW70818.1 - 1.1e-18 66.7 0.1 1.4e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain XPC-binding PF09280.6 AJW70820.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 XPC-binding domain Spore_GerAC PF05504.6 AJW70821.1 - 0.25 11.1 6.7 0.35 10.6 4.6 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Pex19 PF04614.7 AJW70821.1 - 0.54 9.8 4.2 0.71 9.4 2.9 1.2 1 0 0 1 1 1 0 Pex19 protein family PDDEXK_1 PF12705.2 AJW70823.1 - 5.3e-13 48.9 2.2 1.5e-11 44.1 1.5 2.1 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.3 AJW70823.1 - 0.0011 18.2 2.2 0.016 14.3 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2800) DUF3799 PF12684.2 AJW70823.1 - 0.0019 17.5 3.0 0.0034 16.7 1.6 1.7 1 1 0 1 1 1 1 PDDEXK-like domain of unknown function (DUF3799) CheZ PF04344.8 AJW70823.1 - 0.16 11.5 0.7 0.58 9.7 0.1 2.0 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ Dala_Dala_lig_C PF07478.8 AJW70824.1 - 7e-34 116.9 0.0 1.2e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 AJW70824.1 - 6.8e-18 65.0 0.0 1.7e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AJW70824.1 - 1.8e-11 44.1 0.1 3.6e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJW70824.1 - 2.1e-09 36.9 0.0 3.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 AJW70824.1 - 3e-09 36.0 0.0 1.8e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_M20 PF01546.23 AJW70824.1 - 4.3e-07 29.6 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RimK PF08443.6 AJW70824.1 - 4.7e-07 29.4 0.3 7e-06 25.6 0.2 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 AJW70824.1 - 0.0032 17.0 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_N PF01820.16 AJW70824.1 - 0.035 14.4 0.3 1.1 9.5 0.2 2.7 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Pyr_redox_2 PF07992.9 AJW70825.1 - 8.8e-15 55.1 0.0 2.9e-14 53.4 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJW70825.1 - 7.4e-07 29.4 1.1 8.7e-05 22.8 0.5 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_C PF09358.5 AJW70825.1 - 0.032 14.4 0.1 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Pyr_redox_3 PF13738.1 AJW70825.1 - 0.051 13.6 0.0 0.28 11.2 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AJW70825.1 - 0.2 11.4 0.3 3.7 7.3 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Hexapep PF00132.19 AJW70826.1 - 1.4e-16 59.1 14.2 2.8e-06 26.5 0.5 3.4 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJW70826.1 - 4.2e-05 22.9 19.0 0.0046 16.5 2.2 4.9 3 2 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 AJW70827.1 - 3.1e-21 73.8 18.0 1.8e-08 33.5 2.6 3.4 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJW70827.1 - 1.8e-12 46.5 11.9 2.5e-05 23.7 1.4 4.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase HDC PF02329.11 AJW70827.1 - 0.035 12.7 0.1 0.047 12.3 0.1 1.4 1 1 0 1 1 1 0 Histidine carboxylase PI chain Hexapep PF00132.19 AJW70828.1 - 1.9e-22 77.6 15.3 3.1e-08 32.7 1.1 3.2 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJW70828.1 - 6.5e-11 41.5 22.0 6.4e-06 25.6 4.8 4.4 2 2 3 5 5 5 3 Hexapeptide repeat of succinyl-transferase DUF3686 PF12458.3 AJW70828.1 - 0.19 9.9 1.5 1.3 7.2 0.1 1.9 1 1 1 2 2 2 0 ATPase involved in DNA repair S1-like PF14444.1 AJW70828.1 - 0.34 10.6 8.3 2.6 7.8 0.5 3.2 1 1 1 2 2 2 0 S1-like MxiM PF11441.3 AJW70828.1 - 1.1 9.3 4.5 2.5 8.1 3.1 1.7 1 1 0 1 1 1 0 Pilot protein MxiM DUF1416 PF07210.7 AJW70828.1 - 1.9 8.1 6.8 17 5.1 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1416) G_glu_transpept PF01019.16 AJW70829.1 - 4.5e-105 352.0 0.0 5.1e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.13 AJW70829.1 - 0.1 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Asparaginase GATA PF00320.22 AJW70830.1 - 0.024 13.9 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 GATA zinc finger PhnA_Zn_Ribbon PF08274.7 AJW70830.1 - 0.099 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-UBP PF02148.14 AJW70830.1 - 0.12 12.5 0.1 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein FKS1_dom1 PF14288.1 AJW70831.1 - 0.039 13.8 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 GDC-P PF02347.11 AJW70831.1 - 0.045 12.4 0.2 0.054 12.1 0.1 1.0 1 0 0 1 1 1 0 Glycine cleavage system P-protein Bac_DnaA_C PF08299.6 AJW70833.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix DUF4267 PF14087.1 AJW70835.1 - 0.027 14.0 1.3 2.7 7.6 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4267) Ribosomal_L18ae PF01775.12 AJW70837.1 - 0.036 13.9 0.1 0.87 9.4 0.0 1.9 1 1 1 2 2 2 0 Ribosomal L18ae/LX protein domain zf-C2H2_4 PF13894.1 AJW70838.1 - 0.0007 19.7 0.4 0.0014 18.8 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zinc-ribbons_6 PF07191.7 AJW70841.1 - 0.028 14.2 10.4 0.4 10.5 0.8 2.0 1 1 1 2 2 2 0 zinc-ribbons DUF329 PF03884.9 AJW70841.1 - 0.07 12.6 4.1 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-RING_4 PF14570.1 AJW70841.1 - 0.11 12.1 8.6 0.37 10.4 2.2 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C4_Topoisom PF01396.14 AJW70841.1 - 0.16 11.4 3.1 2.1 7.9 0.4 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Spt4 PF06093.8 AJW70841.1 - 0.25 11.2 9.7 3.6 7.5 3.4 2.1 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger zf-FCS PF06467.9 AJW70841.1 - 0.32 10.6 7.1 1 9.0 0.6 2.4 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FANCL_C PF11793.3 AJW70841.1 - 0.78 9.7 6.5 0.7 9.9 0.5 2.5 2 1 0 3 3 2 0 FANCL C-terminal domain PhnA_Zn_Ribbon PF08274.7 AJW70841.1 - 1.1 9.0 4.8 2.5 7.9 0.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon IBR PF01485.16 AJW70841.1 - 1.6 8.7 9.2 1e+02 2.8 6.4 2.1 1 1 0 1 1 1 0 IBR domain Thioredoxin_3 PF13192.1 AJW70841.1 - 1.7 8.5 6.0 8.4 6.2 0.3 2.2 1 1 1 2 2 2 0 Thioredoxin domain YdjO PF14169.1 AJW70841.1 - 1.9 8.0 7.8 1 8.8 1.0 2.2 1 1 1 2 2 2 0 Cold-inducible protein YdjO Sgf11 PF08209.6 AJW70841.1 - 2 7.8 6.0 1.6 8.0 0.2 2.7 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Mut7-C PF01927.11 AJW70841.1 - 2 8.3 5.3 2.2 8.2 3.6 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-TFIIB PF13453.1 AJW70841.1 - 2 7.6 9.0 1.3 8.2 0.4 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_2 PF13240.1 AJW70841.1 - 2.6 7.6 10.0 0.58 9.7 1.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 AJW70841.1 - 4.9 6.8 8.6 2 8.1 0.7 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-ISL3 PF14690.1 AJW70841.1 - 5.6 7.0 9.1 1.3 9.1 1.8 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 AJW70841.1 - 6.2 6.7 9.1 28 4.6 6.3 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 AJW70841.1 - 6.4 6.5 9.1 76 3.0 0.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-AN1 PF01428.11 AJW70842.1 - 0.11 12.3 0.6 0.11 12.3 0.4 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger zf-DNL PF05180.7 AJW70842.1 - 0.13 12.0 2.5 0.2 11.4 1.7 1.5 1 1 0 1 1 1 0 DNL zinc finger C1_4 PF07975.7 AJW70842.1 - 0.16 11.9 7.4 0.32 11.0 5.1 1.7 1 1 0 1 1 1 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.1 AJW70842.1 - 0.19 11.4 2.7 0.2 11.3 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJW70842.1 - 0.2 11.2 0.4 0.2 11.2 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.16 AJW70842.1 - 0.59 10.0 4.9 1.1 9.2 3.4 1.4 1 1 0 1 1 1 0 IBR domain Peptidase_M10 PF00413.19 AJW70843.1 - 3.7e-09 36.4 0.1 9e-09 35.2 0.1 1.6 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 AJW70843.1 - 0.0011 18.3 0.2 0.004 16.5 0.1 1.9 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 AJW70843.1 - 0.0044 15.9 0.3 0.0072 15.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_5 PF13688.1 AJW70843.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 AJW70843.1 - 0.028 14.4 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 AJW70843.1 - 0.03 13.9 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Metallopep PF12044.3 AJW70843.1 - 0.052 11.9 0.4 0.084 11.3 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase family SPAM PF02090.10 AJW70843.1 - 0.054 13.4 3.9 0.11 12.5 2.7 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Reprolysin_3 PF13582.1 AJW70843.1 - 0.072 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Syntaxin_2 PF14523.1 AJW70843.1 - 3.2 7.8 8.6 0.78 9.8 1.8 2.4 2 1 1 3 3 3 0 Syntaxin-like protein Zn_Tnp_IS1595 PF12760.2 AJW70845.1 - 0.0099 15.6 2.6 0.11 12.3 1.9 1.9 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.8 AJW70845.1 - 0.017 14.8 2.5 0.027 14.1 0.1 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 AJW70845.1 - 0.035 14.2 1.6 0.046 13.8 1.1 1.2 1 0 0 1 1 1 0 CHY zinc finger Rubredoxin PF00301.15 AJW70845.1 - 0.04 13.7 2.9 0.084 12.7 2.0 1.6 1 1 0 1 1 1 0 Rubredoxin Tnp_zf-ribbon_2 PF13842.1 AJW70845.1 - 0.042 14.2 6.5 0.2 12.0 0.6 2.1 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon PHD PF00628.24 AJW70845.1 - 0.093 12.4 4.2 0.25 11.0 2.9 1.7 1 1 0 1 1 1 0 PHD-finger DZR PF12773.2 AJW70845.1 - 0.096 12.5 3.2 0.19 11.6 2.2 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF2082 PF09855.4 AJW70845.1 - 0.15 11.9 3.2 0.42 10.4 0.2 2.1 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) HypA PF01155.14 AJW70845.1 - 0.23 11.1 1.1 0.25 11.0 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2296 PF10058.4 AJW70845.1 - 0.38 10.5 6.0 4.5 7.1 4.2 2.0 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-ribbon_3 PF13248.1 AJW70845.1 - 0.38 10.0 2.2 1.1 8.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 AJW70845.1 - 0.54 10.6 4.0 0.67 10.3 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-TFIIB PF13453.1 AJW70845.1 - 0.62 9.2 4.1 4.6 6.5 3.0 1.9 1 1 1 2 2 2 0 Transcription factor zinc-finger zf-LITAF-like PF10601.4 AJW70845.1 - 0.99 9.3 4.3 1.9 8.4 0.3 2.0 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zinc-ribbons_6 PF07191.7 AJW70845.1 - 1 9.2 3.8 3.2 7.6 2.6 1.8 1 1 0 1 1 1 0 zinc-ribbons zf-HIT PF04438.11 AJW70845.1 - 1 9.0 4.6 1.3 8.7 0.5 2.1 2 0 0 2 2 2 0 HIT zinc finger TFIIS_C PF01096.13 AJW70845.1 - 2.5 7.7 5.4 16 5.2 3.8 1.9 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) DUF1319 PF07028.6 AJW70848.1 - 0.078 13.1 1.0 0.092 12.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) zf-C2H2_2 PF12756.2 AJW70849.1 - 0.0042 17.1 1.8 0.0046 17.0 1.3 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 AJW70849.1 - 0.024 14.9 1.5 0.032 14.5 1.0 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AJW70849.1 - 0.027 14.8 1.1 0.037 14.3 0.8 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rop PF01815.11 AJW70849.1 - 0.059 12.8 1.1 0.079 12.4 0.7 1.3 1 0 0 1 1 1 0 Rop protein PyrI_C PF02748.10 AJW70849.1 - 0.27 10.6 3.3 0.18 11.3 1.0 1.7 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GIY-YIG PF01541.19 AJW70850.1 - 2.4e-08 34.2 0.3 3e-08 33.9 0.2 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain VPS28 PF03997.7 AJW70850.1 - 0.15 11.6 0.3 0.2 11.2 0.2 1.1 1 0 0 1 1 1 0 VPS28 protein Helicase_C_2 PF13307.1 AJW70851.1 - 2.1e-22 79.8 0.0 5.3e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 AJW70851.1 - 1.1e-08 35.1 2.1 1.1e-08 35.1 1.5 2.5 1 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 AJW70851.1 - 2e-06 27.3 1.7 2.5e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 AJW70851.1 - 0.00012 21.6 0.1 0.051 13.0 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Ribosomal_S25 PF03297.10 AJW70852.1 - 0.02 14.9 2.8 0.024 14.6 2.0 1.2 1 0 0 1 1 1 0 S25 ribosomal protein ILVD_EDD PF00920.16 AJW70853.1 - 1e-216 720.4 5.0 1.1e-216 720.2 3.4 1.0 1 0 0 1 1 1 1 Dehydratase family Lar_restr_allev PF14354.1 AJW70854.1 - 0.0011 19.2 0.2 0.0014 18.9 0.2 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar TFIIS_C PF01096.13 AJW70854.1 - 0.022 14.3 3.1 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2225 PF09986.4 AJW70854.1 - 0.028 13.8 3.2 0.078 12.4 2.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) HypA PF01155.14 AJW70854.1 - 0.031 13.9 1.5 0.41 10.3 0.1 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AJW70854.1 - 0.05 13.5 2.2 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.1 AJW70854.1 - 0.063 13.3 0.2 4.9 7.2 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Elf1 PF05129.8 AJW70854.1 - 0.064 12.9 1.5 0.14 11.8 1.0 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DNA_RNApol_7kD PF03604.8 AJW70854.1 - 0.075 12.5 0.3 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-H2C2_2 PF13465.1 AJW70854.1 - 0.11 12.8 1.7 6.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.7 AJW70854.1 - 0.11 11.8 3.7 0.58 9.5 2.6 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding zf-trcl PF13451.1 AJW70854.1 - 0.13 11.8 0.9 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain DUF2082 PF09855.4 AJW70854.1 - 0.14 12.0 3.1 0.26 11.1 2.2 1.5 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) CpXC PF14353.1 AJW70854.1 - 0.16 11.9 0.9 0.23 11.4 0.6 1.3 1 1 0 1 1 1 0 CpXC protein zf-RING_4 PF14570.1 AJW70854.1 - 0.21 11.2 2.1 7.2 6.2 0.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Opy2 PF09463.5 AJW70854.1 - 0.26 11.3 1.9 1.8 8.7 0.1 2.1 2 0 0 2 2 2 0 Opy2 protein Rubredoxin PF00301.15 AJW70854.1 - 0.3 11.0 1.7 13 5.7 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin zf-TFIIB PF13453.1 AJW70854.1 - 0.32 10.2 1.6 1.1 8.4 1.1 1.8 1 1 0 1 1 1 0 Transcription factor zinc-finger zf-Sec23_Sec24 PF04810.10 AJW70854.1 - 0.52 9.9 2.3 6.7 6.3 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zinc_ribbon_4 PF13717.1 AJW70854.1 - 1.1 9.0 4.2 2 8.1 0.1 2.2 1 1 2 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJW70854.1 - 1.6 8.3 4.5 2.2 7.9 0.1 2.2 1 1 2 3 3 3 0 zinc-ribbon domain HIT PF01230.18 AJW70856.1 - 9.2e-22 77.4 0.1 1.2e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AJW70856.1 - 1.6e-12 47.6 0.0 1.9e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AJW70856.1 - 0.014 15.0 0.1 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 eRF1_2 PF03464.10 AJW70857.1 - 2.2e-28 99.2 0.0 1.4e-27 96.6 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_1 PF03463.10 AJW70857.1 - 5.2e-20 71.3 0.2 2.1e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.10 AJW70857.1 - 6.3e-20 71.5 0.4 6.3e-19 68.3 0.1 2.2 2 0 0 2 2 2 1 eRF1 domain 3 SpoU_sub_bind PF08032.7 AJW70857.1 - 0.13 12.4 0.3 0.7 10.1 0.0 2.4 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Thioredoxin_4 PF13462.1 AJW70858.1 - 4.4e-35 121.1 0.0 5.1e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJW70858.1 - 2.7e-13 49.9 0.0 2.9e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJW70858.1 - 1e-07 32.1 0.3 7.7e-07 29.3 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 AJW70858.1 - 5.8e-06 25.9 0.0 9.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Ldr_toxin PF13940.1 AJW70858.1 - 0.017 14.8 1.1 0.037 13.8 0.8 1.5 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system DUF2899 PF11449.3 AJW70858.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) DUF4443 PF14544.1 AJW70859.1 - 1e-06 28.6 0.0 1.7e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4443) HTH_45 PF14947.1 AJW70859.1 - 0.001 18.8 0.2 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AJW70859.1 - 0.034 13.7 0.4 0.047 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) CbtB PF09489.5 AJW70860.1 - 2.4e-06 27.3 11.2 0.0002 21.1 7.8 2.1 1 1 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) CbtA PF09490.5 AJW70861.1 - 1.9e-17 63.3 0.1 2.5e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) DUF1624 PF07786.7 AJW70861.1 - 0.0036 16.6 1.1 0.0063 15.8 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1624) Patatin PF01734.17 AJW70861.1 - 0.11 12.3 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase DUF1113 PF06541.6 AJW70861.1 - 0.36 10.5 4.0 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1113) Acyl_transf_3 PF01757.17 AJW70861.1 - 0.42 9.3 9.6 1.7 7.4 6.7 2.0 1 1 0 1 1 1 0 Acyltransferase family Romo1 PF10247.4 AJW70861.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.7 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 5TM-5TMR_LYT PF07694.7 AJW70861.1 - 2.5 7.4 16.1 2.5 7.4 4.7 3.6 2 1 2 4 4 4 0 5TMR of 5TMR-LYT MFS_1 PF07690.11 AJW70861.1 - 3.2 6.3 18.2 0.043 12.5 4.1 2.7 2 1 1 3 3 3 0 Major Facilitator Superfamily DUF3816 PF12822.2 AJW70861.1 - 5.3 6.9 19.1 5 6.9 9.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) HTH_20 PF12840.2 AJW70862.1 - 2.7e-06 27.0 0.0 4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AJW70862.1 - 0.00017 21.2 0.5 0.00036 20.1 0.3 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 AJW70862.1 - 0.00032 20.1 0.2 0.00038 19.9 0.1 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit DUF742 PF05331.6 AJW70862.1 - 0.0015 18.0 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_IclR PF09339.5 AJW70862.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.2 AJW70862.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 AJW70862.1 - 0.18 11.2 0.7 0.45 9.9 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AJW70863.1 - 3.5e-05 23.5 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AJW70863.1 - 6.4e-05 22.5 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.10 AJW70863.1 - 0.00026 20.7 0.1 0.0005 19.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_5 PF01022.15 AJW70863.1 - 0.00046 19.7 0.1 0.00095 18.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF4423 PF14394.1 AJW70863.1 - 0.00047 19.7 0.1 0.00052 19.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_11 PF08279.7 AJW70863.1 - 0.00076 19.0 0.2 0.0014 18.2 0.1 1.5 1 1 0 1 1 1 1 HTH domain DUF1492 PF07374.6 AJW70863.1 - 0.0014 18.7 0.3 0.0019 18.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) FUR PF01475.14 AJW70863.1 - 0.0034 17.2 0.2 0.0051 16.7 0.1 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family Mga PF05043.8 AJW70863.1 - 0.0071 16.6 0.3 0.011 16.0 0.2 1.5 1 1 0 1 1 1 1 Mga helix-turn-helix domain HTH_23 PF13384.1 AJW70863.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 Homeodomain-like domain Fe_dep_repress PF01325.14 AJW70863.1 - 0.013 15.4 0.2 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_45 PF14947.1 AJW70863.1 - 0.027 14.3 0.4 0.1 12.3 0.1 2.0 1 1 1 2 2 2 0 Winged helix-turn-helix HTH_24 PF13412.1 AJW70863.1 - 0.032 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 AJW70863.1 - 0.042 13.4 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Antigen_Bd37 PF11641.3 AJW70863.1 - 0.043 13.0 0.2 0.062 12.5 0.1 1.3 1 1 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein N1221 PF07923.8 AJW70863.1 - 0.046 12.5 0.2 0.051 12.4 0.2 1.1 1 0 0 1 1 1 0 N1221-like protein DUF674 PF05056.7 AJW70863.1 - 0.048 12.2 0.1 0.055 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) RepL PF05732.6 AJW70863.1 - 0.051 12.7 0.1 0.081 12.1 0.0 1.4 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_22 PF13309.1 AJW70863.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.7 AJW70863.1 - 0.076 12.4 0.1 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Sigma-70, region 4 NB-ARC PF00931.17 AJW70863.1 - 0.085 11.7 0.3 0.1 11.4 0.2 1.1 1 0 0 1 1 1 0 NB-ARC domain HTH_28 PF13518.1 AJW70863.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_rep_org_N PF09681.5 AJW70863.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.5 1 1 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Phosphonate-bd PF12974.2 AJW70864.1 - 2.5e-46 158.0 0.2 3.2e-46 157.6 0.2 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Transferrin PF00405.12 AJW70864.1 - 9.3e-07 28.0 0.0 1.9e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Transferrin NMT1_2 PF13379.1 AJW70864.1 - 3.6e-05 23.2 0.1 0.00024 20.5 0.0 2.0 2 0 0 2 2 2 1 NMT1-like family SBP_bac_3 PF00497.15 AJW70864.1 - 4.9e-05 22.6 0.0 0.00015 21.0 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 AJW70864.1 - 0.00015 21.4 0.0 0.007 15.9 0.0 2.3 2 0 0 2 2 2 1 NMT1/THI5 like YhfZ_C PF14503.1 AJW70864.1 - 0.00088 18.6 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 YhfZ C-terminal domain ABC_tran PF00005.22 AJW70865.1 - 7.5e-34 116.9 0.2 1.1e-33 116.4 0.2 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJW70865.1 - 7.8e-10 39.1 2.3 4.8e-07 30.0 1.6 2.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJW70865.1 - 1.7e-07 30.6 4.4 1.4e-06 27.7 3.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AJW70865.1 - 1.4e-05 24.5 0.1 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 AJW70865.1 - 0.001 18.2 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 AJW70865.1 - 0.0016 17.6 0.1 0.0026 16.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 AJW70865.1 - 0.0041 17.4 0.9 0.0055 17.0 0.6 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AJW70865.1 - 0.0051 16.2 0.8 0.0051 16.2 0.6 1.8 1 1 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 AJW70865.1 - 0.0062 16.5 0.0 0.034 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 AJW70865.1 - 0.011 14.9 0.3 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.1 AJW70865.1 - 0.012 15.7 2.9 0.84 9.7 2.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AJW70865.1 - 0.016 14.6 0.1 0.052 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AJW70865.1 - 0.037 14.8 0.0 0.096 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AJW70865.1 - 0.051 14.0 0.2 0.14 12.6 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein G-alpha PF00503.15 AJW70865.1 - 0.074 11.7 0.9 0.12 11.0 0.2 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.18 AJW70865.1 - 0.086 12.6 1.5 3.1 7.6 0.2 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 AJW70865.1 - 0.12 12.6 0.6 0.24 11.7 0.1 1.9 2 1 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.17 AJW70866.1 - 5.5e-16 58.6 14.8 5.5e-16 58.6 10.3 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3154 PF11351.3 AJW70866.1 - 0.16 11.6 3.6 0.85 9.3 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) MotA_ExbB PF01618.11 AJW70866.1 - 0.23 11.0 0.2 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family PrgI PF12666.2 AJW70866.1 - 3.5 7.8 16.1 0.095 12.8 0.8 3.6 3 1 1 4 4 4 0 PrgI family protein DUF1297 PF06973.7 AJW70867.1 - 5e-74 247.7 0.1 6.5e-74 247.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 AJW70867.1 - 3.2e-47 159.3 0.0 5.2e-47 158.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_3 PF02655.9 AJW70867.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain tRNA-synt_2 PF00152.15 AJW70870.1 - 2e-85 286.5 0.6 5.7e-85 285.0 0.4 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AJW70870.1 - 2e-13 50.0 0.0 3.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AJW70870.1 - 0.0098 15.1 0.1 0.084 12.0 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) RE_NgoFVII PF09565.5 AJW70870.1 - 0.018 14.0 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Amidase PF01425.16 AJW70872.1 - 2.3e-132 442.0 0.0 2.6e-132 441.8 0.0 1.0 1 0 0 1 1 1 1 Amidase GatB_N PF02934.10 AJW70873.1 - 1.5e-98 329.2 0.4 1.5e-97 325.9 0.0 2.0 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AJW70873.1 - 2.6e-31 108.3 6.6 4.4e-31 107.6 4.6 1.3 1 0 0 1 1 1 1 GatB domain Glycos_trans_3N PF02885.12 AJW70873.1 - 1.4 8.5 3.8 22 4.7 0.0 3.1 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain AMP-binding PF00501.23 AJW70875.1 - 5e-80 268.9 0.0 6e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AJW70875.1 - 5.7e-15 56.0 0.0 1.2e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mycobact_memb PF05423.8 AJW70875.1 - 0.043 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Mycobacterium membrane protein SIMPL PF04402.9 AJW70875.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Aminotran_1_2 PF00155.16 AJW70876.1 - 1.9e-39 135.6 0.0 2.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AJW70876.1 - 0.00073 18.7 0.0 0.0015 17.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SHOCT PF09851.4 AJW70877.1 - 1.3e-05 24.5 1.8 1.4e-05 24.3 0.2 1.9 2 0 0 2 2 2 1 Short C-terminal domain TrmB PF01978.14 AJW70878.1 - 1.1e-12 47.4 0.0 2.3e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AJW70878.1 - 3.2e-05 23.4 0.0 5.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain z-alpha PF02295.12 AJW70878.1 - 0.00079 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Adenosine deaminase z-alpha domain HTH_24 PF13412.1 AJW70878.1 - 0.0016 17.7 0.3 0.0032 16.8 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 AJW70878.1 - 0.0038 17.3 0.0 0.0074 16.3 0.0 1.5 1 1 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.2 AJW70878.1 - 0.014 15.1 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_9 PF08221.6 AJW70878.1 - 0.016 15.0 0.1 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2250 PF10007.4 AJW70878.1 - 0.037 13.9 0.2 0.23 11.4 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_5 PF01022.15 AJW70878.1 - 0.062 12.9 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Arc_PepC_II PF06847.6 AJW70879.1 - 8e-10 39.0 0.2 2.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Archaeal Peptidase A24 C-terminus Type II Peptidase_A24 PF01478.13 AJW70879.1 - 5.1e-07 29.8 13.9 1.1e-06 28.8 9.6 1.5 1 0 0 1 1 1 1 Type IV leader peptidase family NMN_transporter PF04973.7 AJW70879.1 - 7.3e-05 22.2 5.3 0.00014 21.3 3.6 1.6 1 1 0 1 1 1 1 Nicotinamide mononucleotide transporter CbtA PF09490.5 AJW70879.1 - 0.24 10.6 4.8 1.2 8.3 3.3 2.2 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SPC12 PF06645.8 AJW70879.1 - 0.8 9.5 3.2 1.2 8.9 0.5 2.5 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NfeD PF01957.13 AJW70879.1 - 1.7 8.7 12.6 0.62 10.1 3.6 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding TrmB PF01978.14 AJW70880.1 - 2.4e-11 43.1 0.0 5.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 AJW70880.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain PhoQ_Sensor PF08918.5 AJW70880.1 - 0.042 13.3 0.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 PhoQ Sensor L27_2 PF09045.5 AJW70880.1 - 0.056 12.9 0.0 7.3 6.2 0.0 2.6 2 0 0 2 2 2 0 L27_2 HTH_9 PF08221.6 AJW70880.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain KaiC PF06745.8 AJW70881.1 - 9.7e-56 188.4 0.0 1.1e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 KaiC GvpD PF07088.6 AJW70881.1 - 4.6e-09 35.1 0.1 8.8e-09 34.2 0.1 1.4 1 1 0 1 1 1 1 GvpD gas vesicle protein AAA_25 PF13481.1 AJW70881.1 - 5.4e-08 32.4 0.1 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AJW70881.1 - 0.00081 19.0 0.2 0.0019 17.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RecA PF00154.16 AJW70881.1 - 0.0011 18.1 0.2 0.0018 17.4 0.0 1.5 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 AJW70881.1 - 0.0027 17.8 0.2 0.0058 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AJW70881.1 - 0.0034 17.2 0.0 0.0058 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 AJW70881.1 - 0.0097 14.8 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_18 PF13238.1 AJW70881.1 - 0.026 14.8 2.2 0.09 13.0 1.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AJW70881.1 - 0.034 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AJW70881.1 - 0.036 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 AJW70881.1 - 0.051 14.3 3.1 0.14 12.9 2.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AJW70881.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 AJW70881.1 - 0.083 12.4 0.5 0.19 11.3 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AJW70881.1 - 0.092 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 AJW70881.1 - 0.11 12.5 0.4 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 AJW70881.1 - 0.14 11.5 0.2 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 AJW70881.1 - 0.55 9.7 2.1 1.3 8.6 1.4 1.8 1 1 0 1 1 1 0 AAA domain Saccharop_dh_N PF04455.7 AJW70882.1 - 2e-36 124.2 0.5 4.7e-36 123.0 0.4 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region YhfZ_C PF14503.1 AJW70882.1 - 0.031 13.6 0.3 0.06 12.6 0.2 1.5 1 0 0 1 1 1 0 YhfZ C-terminal domain DUF4579 PF15158.1 AJW70885.1 - 0.02 14.4 0.1 0.022 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) Imm31 PF15595.1 AJW70885.1 - 0.069 12.9 0.4 0.099 12.4 0.2 1.3 1 1 0 1 1 1 0 Immunity protein 31 HD_3 PF13023.1 AJW70886.1 - 1.5e-38 132.1 2.9 1.7e-38 131.9 2.0 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 AJW70886.1 - 9.8e-06 25.5 0.1 3.8e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 HD domain CM_2 PF01817.16 AJW70886.1 - 0.018 15.1 0.5 0.082 13.0 0.1 2.1 2 0 0 2 2 2 0 Chorismate mutase type II Cytochrom_C_2 PF01322.15 AJW70886.1 - 0.053 14.0 1.4 0.33 11.4 0.3 2.5 1 1 1 2 2 2 0 Cytochrome C' TFIIS_M PF07500.9 AJW70886.1 - 1.2 9.2 7.4 2.5 8.2 0.5 2.3 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain Cob_adeno_trans PF01923.13 AJW70887.1 - 4.4e-58 195.6 0.0 5e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF1664 PF07889.7 AJW70888.1 - 0.014 15.1 4.3 0.015 15.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 AJW70888.1 - 0.023 14.8 8.2 0.027 14.6 5.7 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 AJW70888.1 - 0.025 14.1 8.9 0.033 13.7 6.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pyr_excise PF03013.9 AJW70888.1 - 0.039 13.7 1.4 0.044 13.5 1.0 1.0 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Fmp27_WPPW PF10359.4 AJW70888.1 - 0.054 11.9 4.9 0.063 11.6 3.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Syntaxin_2 PF14523.1 AJW70888.1 - 0.078 13.0 3.8 0.092 12.7 2.5 1.3 1 1 0 1 1 1 0 Syntaxin-like protein Vac_Fusion PF02346.11 AJW70888.1 - 0.11 11.9 2.5 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus fusion protein KH_5 PF13184.1 AJW70888.1 - 0.12 12.1 3.0 0.16 11.7 1.8 1.5 1 1 0 1 1 1 0 NusA-like KH domain APG6 PF04111.7 AJW70888.1 - 0.17 10.9 4.9 0.18 10.8 3.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 AJW70888.1 - 0.17 12.0 6.5 0.22 11.7 4.5 1.3 1 0 0 1 1 1 0 Syntaxin Uds1 PF15456.1 AJW70888.1 - 0.17 11.8 2.0 0.2 11.6 1.4 1.1 1 0 0 1 1 1 0 Up-regulated During Septation EMP24_GP25L PF01105.19 AJW70888.1 - 0.41 10.3 3.1 0.42 10.3 2.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF342 PF03961.8 AJW70888.1 - 0.54 8.6 9.5 0.58 8.5 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) XhlA PF10779.4 AJW70888.1 - 0.65 9.9 11.7 1.1 9.1 8.1 1.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF16 PF01519.11 AJW70888.1 - 0.65 10.2 5.4 0.83 9.9 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DASH_Dad3 PF08656.5 AJW70888.1 - 0.66 9.7 4.3 7.3 6.3 2.9 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad3 DUF3373 PF11853.3 AJW70888.1 - 0.87 8.0 3.4 0.9 7.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) V_ATPase_I PF01496.14 AJW70888.1 - 0.95 7.2 4.9 1 7.1 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 AJW70888.1 - 0.97 9.8 4.2 1.1 9.6 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 AJW70888.1 - 1 8.7 11.2 1.3 8.4 7.8 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4200 PF13863.1 AJW70888.1 - 1.2 9.1 10.5 1.9 8.4 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CCDC-167 PF15188.1 AJW70888.1 - 1.3 9.0 5.3 1.6 8.7 3.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Snf7 PF03357.16 AJW70888.1 - 1.3 8.3 8.8 2.7 7.3 2.6 2.0 1 1 1 2 2 2 0 Snf7 IncA PF04156.9 AJW70888.1 - 1.6 8.2 5.8 1.9 8.0 4.0 1.1 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 AJW70888.1 - 4 7.2 11.0 19 5.0 5.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit AAA_23 PF13476.1 AJW70888.1 - 4.7 7.4 12.8 5.5 7.2 8.9 1.1 1 0 0 1 1 1 0 AAA domain HATPase_c PF02518.21 AJW70889.1 - 3.7e-22 78.1 0.1 8.4e-22 76.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW70889.1 - 4e-07 29.9 0.2 8.2e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW70889.1 - 5.9e-07 29.1 0.0 5.9e-07 29.1 0.0 2.4 3 0 0 3 3 3 1 GHKL domain HATPase_c_3 PF13589.1 AJW70889.1 - 0.00086 18.9 0.0 0.00086 18.9 0.0 3.1 3 1 1 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW70889.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain GvpK PF05121.7 AJW70889.1 - 0.029 14.1 1.1 0.029 14.1 0.8 2.3 1 1 0 2 2 2 0 Gas vesicle protein K Response_reg PF00072.19 AJW70890.1 - 2.4e-24 85.5 0.1 3.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Cytomega_UL20A PF05984.7 AJW70891.1 - 0.13 12.4 4.9 0.16 12.2 3.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein RNA_pol_Rpc82 PF05645.8 AJW70891.1 - 0.15 11.5 8.6 0.17 11.4 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 CBFB_NFYA PF02045.10 AJW70891.1 - 1.1 9.8 0.0 1.1 9.8 0.0 2.4 2 1 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF2413 PF10310.4 AJW70891.1 - 2.6 6.7 12.2 2.5 6.8 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3464 PF11947.3 AJW70891.1 - 3.3 7.1 9.3 3.8 6.9 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Pneumo_att_G PF05539.6 AJW70891.1 - 4.6 6.5 11.9 5.3 6.3 8.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RNA_pol_Rpc4 PF05132.9 AJW70891.1 - 4.9 7.1 10.5 4 7.4 6.6 1.4 1 1 0 1 1 1 0 RNA polymerase III RPC4 DUF3807 PF12720.2 AJW70891.1 - 7.8 6.6 11.5 9.6 6.3 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AsnC_trans_reg PF01037.16 AJW70892.1 - 0.0023 17.5 0.5 0.0031 17.1 0.3 1.2 1 0 0 1 1 1 1 AsnC family PTPS PF01242.14 AJW70892.1 - 0.0074 15.9 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF503 PF04456.7 AJW70892.1 - 0.052 13.1 0.3 0.056 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF503) RC-P840_PscD PF10657.4 AJW70892.1 - 0.1 12.4 0.9 0.11 12.3 0.6 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD FAD_binding_4 PF01565.18 AJW70892.1 - 0.1 12.0 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain KH_5 PF13184.1 AJW70892.1 - 0.29 10.9 3.1 0.56 10.0 2.2 1.7 1 1 0 1 1 1 0 NusA-like KH domain AsnC_trans_reg PF01037.16 AJW70893.1 - 5.5e-06 25.9 0.1 6.7e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 AJW70893.1 - 0.023 14.4 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 GYD domain Glyoxalase_2 PF12681.2 AJW70894.1 - 9.7e-16 58.3 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AJW70894.1 - 2.5e-08 33.9 0.0 6.1e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 AJW70894.1 - 0.0035 17.3 0.0 0.15 12.0 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF212 PF02681.9 AJW70894.1 - 0.061 13.0 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Divergent PAP2 family VirDNA-topo-I_N PF09266.5 AJW70895.1 - 0.42 10.5 6.1 1.9 8.4 0.3 2.7 2 1 1 3 3 3 0 Viral DNA topoisomerase I, N-terminal Gly_acyl_tr_C PF08444.5 AJW70896.1 - 0.059 13.3 0.7 0.21 11.6 0.1 2.0 2 1 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DivIC PF04977.10 AJW70897.1 - 0.0043 16.4 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Septum formation initiator Prp19 PF08606.6 AJW70897.1 - 0.016 14.8 1.0 0.031 13.9 0.1 1.8 2 0 0 2 2 2 0 Prp19/Pso4-like HALZ PF02183.13 AJW70897.1 - 0.046 13.4 4.5 0.079 12.6 3.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2756 PF10956.3 AJW70897.1 - 0.052 13.7 4.6 0.11 12.7 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2756) bZIP_1 PF00170.16 AJW70897.1 - 0.36 10.8 5.0 0.61 10.0 3.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 AJW70897.1 - 0.37 10.6 5.4 0.5 10.1 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein zf-PARP PF00645.13 AJW70898.1 - 0.0033 17.6 1.4 0.0037 17.4 1.0 1.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Guanylate_cyc PF00211.15 AJW70899.1 - 4.1e-19 68.6 0.1 5.8e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TetR_C_8 PF14278.1 AJW70900.1 - 0.012 15.9 3.5 1.2 9.5 0.1 3.1 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region MRP-S23 PF10484.4 AJW70900.1 - 0.21 11.5 1.1 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 PALP PF00291.20 AJW70901.1 - 2.9e-80 269.7 0.8 5.3e-80 268.9 0.4 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.20 AJW70901.1 - 0.00063 19.1 0.1 0.0017 17.7 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 AJW70901.1 - 0.012 15.8 0.1 0.034 14.5 0.1 1.7 1 0 0 1 1 1 0 ACT domain AIRC PF00731.15 AJW70902.1 - 1.9e-57 192.7 0.8 2.5e-57 192.3 0.5 1.2 1 0 0 1 1 1 1 AIR carboxylase DUF719 PF05334.8 AJW70902.1 - 0.006 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF719) ATP-grasp PF02222.17 AJW70903.1 - 5.8e-58 195.0 0.0 8.5e-58 194.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AJW70903.1 - 6.9e-17 61.7 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AJW70903.1 - 8.9e-08 31.7 0.1 2.6e-07 30.2 0.1 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AJW70903.1 - 1.2e-05 24.2 0.0 6.6e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AJW70903.1 - 3.5e-05 23.7 0.1 7.9e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 AJW70903.1 - 0.0014 18.1 0.2 0.012 15.1 0.1 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain DUF1297 PF06973.7 AJW70903.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) IncA PF04156.9 AJW70904.1 - 0.042 13.4 3.0 0.042 13.4 2.0 2.3 2 0 0 2 2 2 0 IncA protein DUF4418 PF14387.1 AJW70904.1 - 0.2 11.4 3.8 0.4 10.4 2.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) DZR PF12773.2 AJW70905.1 - 0.38 10.6 3.4 0.76 9.6 2.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 AJW70905.1 - 1.2 8.9 6.0 7.5 6.4 4.1 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-dskA_traR PF01258.12 AJW70905.1 - 6.4 6.6 8.1 37 4.1 5.6 2.1 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger DUF4513 PF14983.1 AJW70906.1 - 0.11 12.2 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) NTP_transferase PF00483.18 AJW70907.1 - 2.3e-30 105.6 0.2 3.8e-30 105.0 0.2 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AJW70907.1 - 1.7e-11 44.4 0.0 2.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJW70907.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_trans_4_2 PF13477.1 AJW70907.1 - 0.035 13.9 0.6 0.051 13.4 0.4 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like Jacalin PF01419.12 AJW70907.1 - 0.1 12.4 1.9 0.17 11.8 1.3 1.3 1 0 0 1 1 1 0 Jacalin-like lectin domain Bac_luciferase PF00296.15 AJW70909.1 - 1.4e-52 178.7 0.0 1.5e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Thiolase_C PF02803.13 AJW70910.1 - 3.9e-12 45.6 0.1 1.1e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 AJW70910.1 - 0.00066 18.7 0.1 0.0017 17.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 AJW70910.1 - 0.025 14.2 0.0 0.075 12.6 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 AJW70910.1 - 0.071 12.5 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF35_N PF12172.3 AJW70911.1 - 0.024 14.5 0.1 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2185 PF09951.4 AJW70913.1 - 0.045 13.5 0.7 0.054 13.3 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) Hjc PF01870.13 AJW70914.1 - 0.00017 21.0 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) Pentapeptide PF00805.17 AJW70916.1 - 5.6e-36 121.2 25.5 1.2e-11 43.5 1.1 4.9 1 1 5 6 6 6 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 AJW70916.1 - 8.7e-16 57.5 1.1 1.7e-09 37.3 0.1 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 AJW70916.1 - 4.4e-13 48.8 1.2 4e-05 23.4 1.9 3.9 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Peptidase_S31 PF05578.7 AJW70916.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 Sec5 PF15469.1 AJW70918.1 - 0.0046 16.7 0.8 0.12 12.0 0.6 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec5 GIT1_C PF12205.3 AJW70918.1 - 0.027 14.2 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term IFT20 PF14931.1 AJW70918.1 - 0.046 13.6 0.4 5.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2383 PF09537.5 AJW70918.1 - 0.053 13.7 0.2 3.7 7.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) Antimicrobial_8 PF08103.6 AJW70919.1 - 0.058 13.3 0.3 0.09 12.7 0.2 1.4 1 0 0 1 1 1 0 Uperin family DNA_topoisoIV PF00521.15 AJW70920.1 - 0.12 11.1 3.1 0.13 11.0 2.2 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A ARID PF01388.16 AJW70920.1 - 0.16 11.8 0.9 0.72 9.7 0.6 1.9 1 1 0 1 1 1 0 ARID/BRIGHT DNA binding domain PALP PF00291.20 AJW70921.1 - 6.5e-41 140.5 0.0 8.6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF21 PF01595.15 AJW70922.1 - 1.3e-53 181.0 0.1 1.7e-53 180.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CorC_HlyC PF03471.12 AJW70922.1 - 4.3e-17 61.6 1.0 4.3e-17 61.6 0.7 2.3 1 1 1 2 2 2 1 Transporter associated domain CBS PF00571.23 AJW70922.1 - 2.7e-16 59.0 0.6 3.7e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain Gp_dh_N PF00044.19 AJW70923.1 - 1.3e-06 28.4 0.0 8.3e-05 22.5 0.0 2.6 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AJW70923.1 - 0.00074 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 AJW70923.1 - 0.0053 17.0 0.0 0.0099 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF999 PF06198.6 AJW70924.1 - 0.081 12.7 0.2 0.098 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF999) ATP-synt PF00231.14 AJW70924.1 - 0.12 11.7 0.1 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 ATP synthase DUF3386 PF11866.3 AJW70924.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) Glyco_tranf_2_3 PF13641.1 AJW70925.1 - 9.4e-38 130.2 0.0 1.3e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AJW70925.1 - 9.5e-35 119.7 0.2 2.1e-34 118.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 AJW70925.1 - 1.5e-27 96.6 0.1 1.5e-27 96.6 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 AJW70925.1 - 2.4e-14 52.6 1.0 6.2e-10 38.0 0.1 3.2 3 0 0 3 3 3 3 Chitin synthase Glyco_tranf_2_2 PF10111.4 AJW70925.1 - 2.1e-11 43.4 0.6 5e-11 42.1 0.4 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AJW70925.1 - 2.8e-10 39.7 0.0 4.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 AJW70925.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.1 AJW70925.1 - 0.035 13.3 1.6 0.15 11.2 0.2 2.2 1 1 1 2 2 2 0 Glycosyltransferase like family Polysacc_deac_1 PF01522.16 AJW70926.1 - 9.8e-11 41.3 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 AJW70926.1 - 8.6e-05 21.6 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CarboxypepD_reg PF13620.1 AJW70926.1 - 0.00038 20.4 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 AJW70926.1 - 0.025 14.4 0.1 0.091 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) Cna_B PF05738.8 AJW70926.1 - 0.065 13.0 2.0 1.2 8.8 0.2 3.5 2 2 0 2 2 2 0 Cna protein B-type domain Polysacc_deac_1 PF01522.16 AJW70927.1 - 0.00027 20.5 0.0 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase IucA_IucC PF04183.7 AJW70927.1 - 0.024 13.8 0.0 0.31 10.2 0.0 2.1 2 0 0 2 2 2 0 IucA / IucC family D-aminoacyl_C PF07908.7 AJW70927.1 - 0.22 10.8 0.1 20 4.5 0.0 2.3 2 0 0 2 2 2 0 D-aminoacylase, C-terminal region Response_reg PF00072.19 AJW70928.1 - 7.4e-17 61.3 0.2 1.2e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DZR PF12773.2 AJW70928.1 - 0.00086 19.0 12.7 0.029 14.1 0.6 2.8 2 1 0 2 2 2 2 Double zinc ribbon HTH_5 PF01022.15 AJW70928.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.14 AJW70928.1 - 0.0054 16.4 0.3 0.02 14.5 0.1 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 AJW70928.1 - 0.014 15.4 0.1 0.038 14.0 0.1 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain zf-Di19 PF05605.7 AJW70928.1 - 0.021 14.9 2.5 0.021 14.9 1.7 2.9 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding HTH_24 PF13412.1 AJW70928.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AJW70928.1 - 0.047 13.5 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zinc-ribbons_6 PF07191.7 AJW70928.1 - 0.083 12.6 18.5 0.19 11.5 5.3 3.1 1 1 2 3 3 3 0 zinc-ribbons AAA PF00004.24 AJW70928.1 - 0.11 12.6 1.5 0.41 10.8 0.6 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ZZ PF00569.12 AJW70928.1 - 0.75 9.3 15.6 2.7 7.6 2.3 3.5 3 0 0 3 3 3 0 Zinc finger, ZZ type DnaJ_CXXCXGXG PF00684.14 AJW70928.1 - 1.4 9.0 11.6 4.5 7.4 0.7 2.7 2 1 0 2 2 2 0 DnaJ central domain Zn-ribbon_8 PF09723.5 AJW70928.1 - 2.1 8.3 20.3 4.3 7.3 0.1 5.4 3 2 2 5 5 5 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 AJW70928.1 - 2.6 7.7 17.4 11 5.7 1.3 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 AJW70928.1 - 4.1 7.0 9.7 1.7 8.2 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Cytochrom_c3_2 PF14537.1 AJW70928.1 - 4.3 7.7 15.8 12 6.2 0.6 2.5 2 0 0 2 2 2 0 Cytochrome c3 zf-ribbon_3 PF13248.1 AJW70928.1 - 4.7 6.5 16.1 0.43 9.8 2.0 3.6 4 0 0 4 4 3 0 zinc-ribbon domain PHD PF00628.24 AJW70928.1 - 4.9 6.9 21.1 37 4.1 2.3 4.1 2 2 2 4 4 4 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 AJW70928.1 - 9.5 6.1 17.3 0.98 9.2 0.5 4.1 3 1 0 3 3 3 0 Transposase zinc-ribbon domain A2M_N PF01835.14 AJW70929.1 - 0.0033 17.6 0.3 0.0068 16.6 0.2 1.5 1 1 0 1 1 1 1 MG2 domain DUF4448 PF14610.1 AJW70929.1 - 0.05 13.0 1.3 0.067 12.6 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Thioredoxin_4 PF13462.1 AJW70930.1 - 4.6e-31 108.0 0.0 5.9e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJW70930.1 - 3.4e-17 62.6 0.1 6.5e-16 58.4 0.1 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJW70930.1 - 1.6e-07 31.5 0.0 8.5e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AJW70930.1 - 0.0098 15.9 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like HMG_CoA_synt_C PF08540.5 AJW70931.1 - 7.1e-33 114.2 0.2 1.1e-32 113.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 AJW70931.1 - 1.6e-30 105.9 0.1 2.9e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ParB PF08775.5 AJW70933.1 - 0.022 15.0 1.8 0.022 15.0 1.3 1.5 2 0 0 2 2 2 0 ParB family Methyltrans_RNA PF04452.9 AJW70933.1 - 0.2 10.7 2.0 0.32 10.1 1.4 1.3 1 0 0 1 1 1 0 RNA methyltransferase SDF PF00375.13 AJW70934.1 - 2.5e-112 375.4 44.0 2.9e-112 375.3 30.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family AAA_26 PF13500.1 AJW70935.1 - 2.4e-39 135.0 0.0 2.8e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 AJW70935.1 - 2.3e-10 40.2 0.2 2.9e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.6 AJW70935.1 - 0.0011 17.7 0.4 0.095 11.3 0.4 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1611) ParA PF10609.4 AJW70935.1 - 0.016 15.0 2.0 0.03 14.1 0.7 2.1 1 1 1 2 2 2 0 ParA/MinD ATPase like Secretin PF00263.16 AJW70935.1 - 0.063 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Aminotran_3 PF00202.16 AJW70936.1 - 5.5e-92 308.2 0.0 6.4e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 AJW70936.1 - 0.00078 18.6 0.0 0.0019 17.4 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase DUF16 PF01519.11 AJW70936.1 - 0.11 12.7 0.9 0.45 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 BATS PF06968.8 AJW70937.1 - 3.1e-20 71.8 0.0 8.7e-20 70.3 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 AJW70937.1 - 2.5e-19 70.0 0.7 5.4e-19 68.9 0.5 1.5 1 0 0 1 1 1 1 Radical SAM superfamily MRP-S28 PF10213.4 AJW70937.1 - 0.04 13.9 0.1 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein HhH-GPD PF00730.20 AJW70937.1 - 0.13 12.6 0.0 7.4 6.8 0.0 2.5 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein zf-HC5HC2H PF13771.1 AJW70937.1 - 1.9 8.7 4.8 6 7.0 0.2 2.6 3 0 0 3 3 3 0 PHD-like zinc-binding domain DsbD PF02683.10 AJW70938.1 - 1.3e-45 155.6 19.3 1.5e-45 155.4 13.4 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 AJW70938.1 - 3.9e-09 36.5 16.7 5.3e-09 36.1 11.6 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2910 PF11139.3 AJW70938.1 - 0.00023 20.3 8.4 0.00023 20.3 5.8 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2910) DUF4112 PF13430.1 AJW70938.1 - 0.68 9.8 4.7 0.25 11.2 0.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4112) Redoxin PF08534.5 AJW70939.1 - 4.7e-09 35.9 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 AJW70939.1 - 4.6e-08 32.7 0.0 8.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 AJW70939.1 - 0.0051 16.9 0.1 0.0099 15.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Snf7 PF03357.16 AJW70940.1 - 8.7e-08 31.7 0.4 1.4e-07 31.0 0.3 1.3 1 0 0 1 1 1 1 Snf7 Cu-oxidase_2 PF07731.9 AJW70941.1 - 3.4e-15 55.7 12.8 2.3e-10 40.1 4.9 3.7 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AJW70941.1 - 3.6e-10 39.5 6.9 8.5e-07 28.7 0.1 3.2 3 1 0 3 3 3 2 Multicopper oxidase Copper-bind PF00127.15 AJW70941.1 - 0.0038 17.4 0.5 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family WbqC PF08889.6 AJW70942.1 - 0.024 14.1 0.6 0.029 13.8 0.1 1.4 2 0 0 2 2 2 0 WbqC-like protein family Amidase02_C PF12123.3 AJW70942.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF371 PF04027.8 AJW70944.1 - 2.6e-42 143.6 0.0 2.8e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) DUF1628 PF07790.6 AJW70945.1 - 0.073 13.8 0.3 0.11 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF1517 PF07466.6 AJW70945.1 - 0.1 11.5 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Proteasome PF00227.21 AJW70946.1 - 4.1e-55 186.0 0.5 5.3e-55 185.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AJW70946.1 - 1.5e-14 52.9 0.6 5.1e-14 51.2 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltrn_RNA_3 PF02598.12 AJW70947.1 - 1.5e-52 178.8 0.1 1.7e-52 178.5 0.1 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 AJW70947.1 - 0.003 17.4 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family DDDD PF10161.4 AJW70948.1 - 0.073 12.7 0.1 0.084 12.5 0.0 1.0 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Ribosomal_L3 PF00297.17 AJW70949.1 - 3.7e-55 187.1 2.0 4.3e-55 186.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L4 PF00573.17 AJW70950.1 - 1.7e-43 148.2 0.1 2e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.15 AJW70951.1 - 4e-12 45.9 2.0 9.6e-12 44.6 1.4 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.14 AJW70951.1 - 0.002 17.5 0.1 0.0034 16.8 0.1 1.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain RRM_5 PF13893.1 AJW70951.1 - 0.0063 16.3 0.5 0.04 13.7 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AJW70951.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MRP-L27 PF09809.4 AJW70951.1 - 0.12 12.0 0.4 2.4 7.8 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L27 YcxB PF14317.1 AJW70951.1 - 0.14 11.3 0.1 0.44 9.8 0.0 1.7 2 0 0 2 2 2 0 YcxB-like protein Ribosomal_S19 PF00203.16 AJW70952.1 - 2.7e-24 84.5 0.5 3.6e-24 84.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L22 PF00237.14 AJW70953.1 - 5.6e-30 103.3 1.2 6.9e-30 103.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e BRX_N PF13713.1 AJW70953.1 - 0.072 12.5 0.2 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Ribosomal_S3_C PF00189.15 AJW70954.1 - 5.1e-14 52.2 0.2 1.2e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AJW70954.1 - 3.4e-13 48.9 0.3 1e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_4 PF13083.1 AJW70954.1 - 0.0089 15.6 0.0 0.03 13.9 0.0 1.9 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 AJW70954.1 - 0.019 14.6 0.3 0.14 11.7 0.1 2.5 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 AJW70954.1 - 0.2 11.3 1.1 0.51 10.0 0.3 2.0 2 0 0 2 2 2 0 KH domain Ribosomal_L29 PF00831.18 AJW70955.1 - 2.6e-14 52.6 5.2 3e-14 52.4 3.6 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein BLOC1_2 PF10046.4 AJW70955.1 - 0.015 15.4 0.8 0.02 15.0 0.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 AJW70955.1 - 0.088 12.4 2.1 0.098 12.2 1.4 1.1 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 AJW70955.1 - 0.11 12.3 0.3 0.13 12.1 0.2 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 AJW70955.1 - 1.9 7.3 5.1 2.1 7.2 3.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0086 PF01868.11 AJW70956.1 - 6.7e-26 89.7 0.1 7.3e-26 89.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF4430 PF14478.1 AJW70956.1 - 0.0077 16.2 0.5 0.0093 15.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Ribosomal_S17 PF00366.15 AJW70957.1 - 3.4e-16 59.0 0.6 4.4e-16 58.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.14 AJW70958.1 - 2.3e-33 114.5 0.4 2.5e-33 114.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e KOW PF00467.24 AJW70959.1 - 1.6e-06 27.5 1.7 4.6e-06 26.1 1.2 1.8 1 0 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.9 AJW70959.1 - 0.083 11.9 0.2 0.15 11.1 0.1 1.5 1 1 0 1 1 1 0 RNA methyltransferase Ribosomal_S4e PF00900.15 AJW70960.1 - 2.6e-23 81.4 0.5 5.5e-23 80.4 0.4 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 AJW70960.1 - 3.3e-13 49.2 3.6 5.3e-13 48.5 2.5 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 AJW70960.1 - 0.00047 19.5 0.1 0.0013 18.1 0.0 1.8 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 AJW70960.1 - 0.032 13.9 1.4 0.087 12.5 0.2 2.5 2 0 0 2 2 2 0 KOW motif Ribosomal_L5_C PF00673.16 AJW70961.1 - 9.1e-24 83.0 0.0 1.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AJW70961.1 - 2.8e-09 36.6 0.7 5.9e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Toxin_55 PF15606.1 AJW70961.1 - 0.099 12.6 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative toxin 55 Ribosomal_S14 PF00253.16 AJW70962.1 - 1.9e-15 55.9 3.8 2.2e-15 55.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.9 AJW70962.1 - 0.0089 15.6 2.0 0.017 14.7 1.2 1.6 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS DZR PF12773.2 AJW70962.1 - 0.098 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-dskA_traR PF01258.12 AJW70962.1 - 1.9 8.2 4.5 25 4.7 3.2 2.1 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Ribosomal_S8 PF00410.14 AJW70963.1 - 7e-22 77.6 0.0 8.8e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.18 AJW70964.1 - 3.8e-11 43.3 5.6 1.2e-05 25.6 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 S_layer_C PF05124.7 AJW70964.1 - 0.021 14.4 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region DZR PF12773.2 AJW70966.1 - 0.0035 17.1 0.2 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-IS66 PF13005.2 AJW70966.1 - 0.0091 15.9 0.4 1.2 9.2 0.1 2.5 2 0 0 2 2 2 1 zinc-finger binding domain of transposase IS66 C1_4 PF07975.7 AJW70966.1 - 0.013 15.5 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 AJW70966.1 - 0.018 15.2 0.1 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 AJW70966.1 - 0.035 14.0 0.3 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 AJW70966.1 - 0.065 12.7 2.0 1.9 8.0 0.3 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.7 AJW70966.1 - 0.083 12.3 1.1 3.3 7.1 0.1 2.4 2 0 0 2 2 2 0 HypF finger DUF35_N PF12172.3 AJW70966.1 - 0.12 12.3 1.9 3.2 7.7 0.2 2.2 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-LYAR PF08790.6 AJW70966.1 - 0.12 12.0 2.1 4.2 7.1 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-RING_3 PF14369.1 AJW70966.1 - 0.14 12.1 0.5 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 zinc-finger zf-C2H2 PF00096.21 AJW70966.1 - 0.18 12.2 1.2 2.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4257 PF14074.1 AJW70967.1 - 0.00029 20.4 0.4 0.00034 20.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) Tic20 PF09685.5 AJW70967.1 - 0.0044 16.9 0.3 0.0052 16.7 0.2 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF2207 PF09972.4 AJW70967.1 - 0.011 14.3 0.3 0.011 14.3 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3522 PF12036.3 AJW70967.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF973 PF06157.6 AJW70967.1 - 0.019 13.9 0.1 0.024 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2407_C PF13373.1 AJW70967.1 - 0.023 14.6 0.2 0.032 14.1 0.1 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain Bac_Ubq_Cox PF01654.12 AJW70967.1 - 0.041 12.2 0.1 0.046 12.1 0.0 1.0 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase Cyto_ox_2 PF02322.10 AJW70967.1 - 0.05 12.7 0.0 0.051 12.7 0.0 1.0 1 0 0 1 1 1 0 Cytochrome oxidase subunit II TctB PF07331.6 AJW70967.1 - 0.053 13.1 0.2 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family MFS_1 PF07690.11 AJW70967.1 - 0.055 12.1 1.9 0.067 11.9 1.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Yip1 PF04893.12 AJW70967.1 - 0.057 12.9 0.8 0.069 12.6 0.6 1.2 1 0 0 1 1 1 0 Yip1 domain Choline_transpo PF04515.7 AJW70967.1 - 0.059 12.1 0.1 0.066 11.9 0.1 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter HlyIII PF03006.15 AJW70967.1 - 0.077 12.3 0.0 0.088 12.2 0.0 1.0 1 0 0 1 1 1 0 Haemolysin-III related DUF3185 PF11381.3 AJW70967.1 - 0.079 12.7 0.8 0.079 12.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF4293 PF14126.1 AJW70967.1 - 0.12 12.3 0.5 0.14 12.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF4131 PF13567.1 AJW70967.1 - 0.14 11.5 0.4 0.15 11.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF308 PF03729.8 AJW70967.1 - 0.33 10.9 7.1 1.7 8.6 0.1 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF3899 PF13038.1 AJW70967.1 - 0.41 10.8 2.6 1.5 9.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4064 PF13273.1 AJW70967.1 - 0.64 10.1 9.2 2.5 8.2 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) SdpI PF13630.1 AJW70967.1 - 7.1 6.4 9.1 31 4.3 6.4 1.8 1 1 0 1 1 1 0 SdpI/YhfL protein family DUF2299 PF10061.4 AJW70968.1 - 6.9e-06 25.5 0.6 8.5e-06 25.2 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) FG-GAP PF01839.18 AJW70971.1 - 0.034 13.8 0.5 0.13 12.0 0.4 2.1 1 0 0 1 1 1 0 FG-GAP repeat Big_1 PF02369.11 AJW70971.1 - 2.6 8.0 9.3 3.8 7.4 0.9 2.3 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 1) DUF4352 PF11611.3 AJW70972.1 - 8.7e-13 48.4 1.5 1.1e-12 48.2 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) MacB_PCD PF12704.2 AJW70972.1 - 0.024 14.2 3.7 0.37 10.3 1.2 2.0 1 1 1 2 2 2 0 MacB-like periplasmic core domain tRNA_deacylase PF04414.7 AJW70972.1 - 0.029 13.4 0.1 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase S1FA PF04689.8 AJW70972.1 - 0.077 12.8 0.6 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Pyridox_oxidase PF01243.15 AJW70974.1 - 1.5e-15 56.9 0.0 2.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AJW70974.1 - 0.00024 20.9 0.0 0.00053 19.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HTH_20 PF12840.2 AJW70976.1 - 2.5e-09 36.7 0.2 4.3e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AJW70976.1 - 2e-06 27.3 0.4 1.7e-05 24.4 0.3 2.2 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.5 AJW70976.1 - 1.4e-05 24.6 0.3 2.7e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain FUR PF01475.14 AJW70976.1 - 0.00032 20.6 0.7 0.00064 19.6 0.5 1.6 1 1 0 1 1 1 1 Ferric uptake regulator family Replic_Relax PF13814.1 AJW70976.1 - 0.0018 18.1 0.1 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Replication-relaxation TFIIE_alpha PF02002.12 AJW70976.1 - 0.024 14.1 0.8 0.089 12.3 0.0 2.0 2 1 0 2 2 2 0 TFIIE alpha subunit DUF2004 PF09406.5 AJW70976.1 - 0.047 13.7 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) Rep_fac_C PF08542.6 AJW70976.1 - 0.053 13.4 1.3 1.4 8.9 0.2 2.6 2 1 0 2 2 2 0 Replication factor C C-terminal domain HTH_11 PF08279.7 AJW70976.1 - 0.11 12.1 0.6 0.97 9.1 0.4 2.2 1 1 0 1 1 1 0 HTH domain Response_reg PF00072.19 AJW70979.1 - 2.3e-20 72.6 0.1 2.6e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain eRF1_2 PF03464.10 AJW70979.1 - 0.1 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 eRF1 domain 2 HATPase_c PF02518.21 AJW70980.1 - 2.3e-27 94.9 0.1 4.5e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 AJW70980.1 - 3.4e-17 62.7 0.1 6.5e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 AJW70980.1 - 4.8e-13 48.9 0.0 3.4e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 AJW70980.1 - 4e-11 42.6 0.0 8.7e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 AJW70980.1 - 4.3e-06 26.7 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 AJW70980.1 - 6.9e-06 26.0 1.0 1.3e-05 25.2 0.2 1.9 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.1 AJW70980.1 - 9.8e-05 21.9 0.3 0.00029 20.5 0.2 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AJW70980.1 - 0.00022 20.8 0.2 0.00055 19.6 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.1 AJW70980.1 - 0.02 14.7 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain DUF427 PF04248.7 AJW70981.1 - 8.6e-30 102.2 0.5 9.4e-30 102.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DAHP_synth_1 PF00793.15 AJW70981.1 - 0.076 11.6 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family GATase_2 PF00310.16 AJW70982.1 - 1.5e-20 73.2 0.0 1e-14 54.0 0.0 3.2 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AJW70982.1 - 3.1e-17 62.7 0.0 9.9e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AJW70982.1 - 9.3e-15 54.4 0.0 8.1e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 AJW70982.1 - 5e-13 48.8 0.1 1.2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 AJW70982.1 - 2.9e-06 26.1 0.0 5.9e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_3 PF15610.1 AJW70982.1 - 0.059 12.2 0.1 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 PRTase ComF-like Pribosyltran_N PF13793.1 AJW70982.1 - 0.092 12.4 0.1 0.29 10.8 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase RQC PF09382.5 AJW70982.1 - 0.16 11.7 0.0 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 RQC domain AIRS_C PF02769.17 AJW70983.1 - 4e-44 150.3 0.7 6.6e-26 91.1 0.4 2.2 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AJW70983.1 - 6.3e-39 132.1 0.5 3.4e-21 75.3 0.3 2.5 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain GATase_5 PF13507.1 AJW70984.1 - 1.8e-42 145.0 0.0 4.8e-42 143.6 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 AJW70984.1 - 7.7e-10 38.5 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 AJW70984.1 - 1.4e-09 37.7 0.0 1.4e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 AJW70984.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 AJW70984.1 - 1.6e-05 24.2 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_C26 PF07722.8 AJW70984.1 - 0.0013 18.2 0.2 0.0044 16.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 AJW70984.1 - 0.035 13.7 0.0 0.074 12.6 0.0 1.5 2 0 0 2 2 2 0 SNO glutamine amidotransferase family PurS PF02700.9 AJW70985.1 - 3.6e-20 71.7 0.3 3.9e-20 71.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase TatC PF00902.13 AJW70989.1 - 1.2e-61 207.8 13.8 1.4e-61 207.6 9.6 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) MttA_Hcf106 PF02416.11 AJW70990.1 - 6.5e-09 34.7 6.8 3.6e-08 32.4 4.7 2.0 1 1 0 1 1 1 1 mttA/Hcf106 family DUF4179 PF13786.1 AJW70990.1 - 0.0066 16.6 0.4 0.0081 16.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) Polyketide_cyc PF03364.15 AJW70991.1 - 0.00019 21.3 0.0 0.00076 19.4 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 AJW70991.1 - 0.00091 19.4 0.0 0.0015 18.7 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Cytokin_check_N PF10407.4 AJW70991.1 - 0.18 11.4 0.8 4.7 6.9 0.0 2.7 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Flavoprotein PF02441.14 AJW70992.1 - 3.8e-31 107.4 0.5 5.1e-31 107.0 0.3 1.1 1 0 0 1 1 1 1 Flavoprotein DUF4366 PF14283.1 AJW70993.1 - 0.025 13.9 0.0 0.028 13.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1297 PF06973.7 AJW70994.1 - 1.1e-73 246.5 0.1 1.7e-73 245.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 AJW70994.1 - 1.6e-47 160.3 0.0 3.2e-47 159.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) zf-FPG_IleRS PF06827.9 AJW70996.1 - 0.0016 18.0 0.8 0.23 11.1 0.0 2.3 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS DUF2387 PF09526.5 AJW70996.1 - 0.0033 17.3 0.7 0.0045 16.8 0.5 1.3 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) zf-trcl PF13451.1 AJW70996.1 - 0.018 14.6 0.1 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain Lar_restr_allev PF14354.1 AJW70996.1 - 0.019 15.2 0.1 0.025 14.9 0.1 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.1 AJW70996.1 - 0.13 11.9 1.9 0.38 10.4 1.3 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 AJW70996.1 - 0.15 11.5 0.6 8.8 5.9 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain zinc_ribbon_5 PF13719.1 AJW70996.1 - 0.17 11.4 1.8 0.54 9.8 1.2 1.7 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 AJW70996.1 - 0.22 11.3 2.1 0.45 10.3 1.4 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 AJW70996.1 - 0.44 10.5 2.1 12 5.9 0.2 2.5 2 1 1 3 3 3 0 zinc-finger Lentiviral_Tat PF02998.9 AJW70997.1 - 0.058 13.2 0.3 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Lentiviral Tat protein DUF3444 PF11926.3 AJW70998.1 - 0.033 13.3 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) CARDB PF07705.6 AJW70998.1 - 0.071 13.1 0.7 0.096 12.7 0.5 1.1 1 0 0 1 1 1 0 CARDB TBPIP PF07106.8 AJW70999.1 - 0.0028 17.2 0.7 0.003 17.1 0.5 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CDT1 PF08839.6 AJW70999.1 - 0.035 14.0 0.6 0.042 13.7 0.4 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like TMF_DNA_bd PF12329.3 AJW70999.1 - 0.036 13.8 1.7 0.039 13.7 1.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 AJW70999.1 - 0.044 13.9 0.8 0.057 13.5 0.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YgaB PF14182.1 AJW70999.1 - 0.047 13.9 1.3 0.057 13.6 0.9 1.3 1 0 0 1 1 1 0 YgaB-like protein FlaC_arch PF05377.6 AJW70999.1 - 0.055 13.3 1.4 0.35 10.7 0.2 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Kinetocho_Slk19 PF12709.2 AJW70999.1 - 0.059 13.4 1.0 0.062 13.3 0.7 1.1 1 0 0 1 1 1 0 Central kinetochore-associated Mt_ATP-synt_D PF05873.7 AJW70999.1 - 0.065 12.8 0.9 0.075 12.6 0.6 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) HR1 PF02185.11 AJW70999.1 - 0.078 12.7 2.5 0.12 12.1 1.7 1.4 1 1 0 1 1 1 0 Hr1 repeat Bap31 PF05529.7 AJW70999.1 - 0.11 11.9 0.5 0.12 11.8 0.3 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FlxA PF14282.1 AJW70999.1 - 0.11 12.4 3.0 0.14 12.0 1.0 1.6 1 1 1 2 2 2 0 FlxA-like protein Toxin_52 PF15605.1 AJW70999.1 - 0.11 12.3 0.2 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 Putative toxin 52 DUF1192 PF06698.6 AJW70999.1 - 0.12 12.2 0.5 0.29 10.9 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Osmo_CC PF08946.5 AJW70999.1 - 2.7 8.0 5.6 1.3 9.0 1.4 2.0 1 1 1 2 2 2 0 Osmosensory transporter coiled coil DNase-RNase PF02577.9 AJW71001.1 - 1.1e-06 27.8 0.0 1.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease TrkH PF02386.11 AJW71002.1 - 3.3e-25 88.4 39.4 7.6e-23 80.6 16.7 3.6 1 1 1 3 3 3 2 Cation transport protein CBS PF00571.23 AJW71002.1 - 4.2e-19 68.0 4.6 3.8e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain Fun_ATP-synt_8 PF05933.8 AJW71003.1 - 0.056 13.4 0.3 0.056 13.4 0.2 3.5 4 0 0 4 4 4 0 Fungal ATP synthase protein 8 (A6L) Herpes_UL49_5 PF05702.6 AJW71003.1 - 6.3 6.7 7.0 1.1 9.2 0.1 2.8 2 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein DUF1825 PF08855.5 AJW71006.1 - 0.0041 17.0 2.7 0.017 15.0 0.3 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF1825) DUF2408 PF10303.4 AJW71006.1 - 0.0072 16.4 0.8 0.014 15.4 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) HTH_11 PF08279.7 AJW71006.1 - 0.0081 15.7 0.3 0.078 12.6 0.2 2.4 1 1 0 1 1 1 1 HTH domain Syntaxin-6_N PF09177.6 AJW71006.1 - 0.011 16.1 2.3 0.019 15.3 1.3 1.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FUR PF01475.14 AJW71006.1 - 0.02 14.8 2.8 0.098 12.5 2.0 2.0 1 1 0 1 1 1 0 Ferric uptake regulator family V_ATPase_I PF01496.14 AJW71006.1 - 0.021 12.6 5.1 0.029 12.2 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HTH_24 PF13412.1 AJW71006.1 - 0.044 13.1 2.2 0.08 12.3 0.2 2.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DASH_Dad3 PF08656.5 AJW71006.1 - 0.046 13.4 1.2 0.2 11.3 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Prefoldin_2 PF01920.15 AJW71006.1 - 0.078 12.7 3.7 0.76 9.5 1.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit MitMem_reg PF13012.1 AJW71006.1 - 0.12 12.4 3.0 0.25 11.4 1.7 1.9 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Mut7-C PF01927.11 AJW71007.1 - 2.3e-08 34.1 0.1 2.5e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain PIN PF01850.16 AJW71007.1 - 0.0031 17.8 0.0 0.007 16.6 0.0 1.6 1 1 1 2 2 2 1 PIN domain Fcf1 PF04900.7 AJW71007.1 - 0.0043 17.1 0.0 0.0049 16.9 0.0 1.1 1 0 0 1 1 1 1 Fcf1 DUF4411 PF14367.1 AJW71007.1 - 0.016 14.8 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) DUF562 PF04763.7 AJW71007.1 - 0.036 13.3 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF562) UPF0180 PF03698.8 AJW71007.1 - 0.053 13.3 0.1 0.096 12.5 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0180) RNase_Zc3h12a PF11977.3 AJW71007.1 - 0.08 12.7 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain PTS_IIB PF02302.12 AJW71007.1 - 0.1 13.0 0.1 1.3 9.5 0.0 2.1 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Spermine_synth PF01564.12 AJW71008.1 - 0.0096 14.8 0.9 0.011 14.6 0.6 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase DUF3599 PF12206.3 AJW71008.1 - 0.024 14.9 0.4 0.027 14.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) DUF4164 PF13747.1 AJW71008.1 - 0.03 14.4 0.8 0.037 14.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Unstab_antitox PF09720.5 AJW71008.1 - 0.053 13.2 0.4 0.08 12.6 0.3 1.3 1 0 0 1 1 1 0 Putative addiction module component DUF507 PF04368.8 AJW71008.1 - 0.054 13.1 6.9 0.074 12.6 4.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF507) FCH PF00611.18 AJW71008.1 - 0.077 13.1 2.0 0.091 12.9 1.4 1.2 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1911 PF08929.5 AJW71008.1 - 0.083 13.5 1.2 0.094 13.4 0.8 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1911) RepC PF06504.6 AJW71008.1 - 0.12 11.2 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Replication protein C (RepC) DUF1053 PF06327.9 AJW71008.1 - 0.86 9.9 5.0 1 9.7 3.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Wbp11 PF09429.5 AJW71008.1 - 1.1 9.2 7.0 1.5 8.8 4.9 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 PRP1_N PF06424.7 AJW71008.1 - 4 7.7 6.8 4.8 7.5 4.7 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Histone_HNS PF00816.16 AJW71008.1 - 6.7 7.3 7.8 1.2 9.6 3.0 1.6 2 1 0 2 2 1 0 H-NS histone family Orbi_VP5 PF00901.12 AJW71009.1 - 0.026 12.7 2.1 0.03 12.5 1.5 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Rho_GDI PF02115.12 AJW71009.1 - 0.058 12.8 0.5 0.057 12.8 0.4 1.0 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor NRDE-2 PF08424.5 AJW71009.1 - 0.068 12.0 0.7 0.067 12.0 0.5 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference RE_Alw26IDE PF09665.5 AJW71009.1 - 0.11 11.2 1.9 0.11 11.1 1.3 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Glyco_hydro_72 PF03198.9 AJW71009.1 - 0.11 11.4 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Glucanosyltransferase DUF946 PF06101.6 AJW71009.1 - 0.12 10.2 0.1 0.13 10.2 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) DUF1664 PF07889.7 AJW71009.1 - 0.3 10.8 1.8 0.36 10.6 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Swi5 PF07061.6 AJW71009.1 - 0.98 9.2 4.8 1.9 8.3 0.6 2.0 1 1 1 2 2 2 0 Swi5 PV-1 PF06637.6 AJW71010.1 - 0.017 13.7 0.1 0.021 13.4 0.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) G-alpha PF00503.15 AJW71010.1 - 0.059 12.0 1.3 0.066 11.8 0.9 1.0 1 0 0 1 1 1 0 G-protein alpha subunit AvrL567-A PF11529.3 AJW71011.1 - 0.066 13.2 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A Methyltransf_3 PF01596.12 AJW71012.1 - 3e-33 114.6 0.6 3.4e-33 114.4 0.4 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 AJW71012.1 - 1e-13 51.9 0.0 1.5e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJW71012.1 - 1.7e-08 34.2 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AJW71012.1 - 2.8e-08 34.3 0.0 4.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW71012.1 - 5.8e-06 25.9 0.6 7.9e-06 25.5 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 AJW71012.1 - 0.0037 16.5 0.2 0.005 16.1 0.1 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_4 PF02390.12 AJW71012.1 - 0.0068 15.4 0.9 0.052 12.5 0.2 2.2 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 AJW71012.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PTase_Orf2 PF11468.3 AJW71012.1 - 0.033 13.3 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 Methyltransf_15 PF09445.5 AJW71012.1 - 0.037 13.5 0.1 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TrkA_N PF02254.13 AJW71012.1 - 0.098 12.6 0.0 5.9 6.9 0.0 2.5 1 1 1 2 2 2 0 TrkA-N domain UPF0020 PF01170.13 AJW71012.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Acyl_transf_3 PF01757.17 AJW71014.1 - 0.035 12.9 0.1 0.038 12.8 0.1 1.0 1 0 0 1 1 1 0 Acyltransferase family PepSY_TM_3 PF13706.1 AJW71014.1 - 0.051 12.9 1.8 0.61 9.5 0.4 2.1 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2964 PF11177.3 AJW71014.1 - 0.52 10.2 0.2 0.52 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) COPI_assoc PF08507.5 AJW71014.1 - 0.66 9.6 4.5 6.1 6.5 0.1 2.0 1 1 1 2 2 2 0 COPI associated protein IncA PF04156.9 AJW71014.1 - 2.8 7.5 4.4 19 4.8 0.9 2.0 1 1 1 2 2 2 0 IncA protein Uteroglobin PF01099.12 AJW71015.1 - 0.0024 17.6 0.1 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Uteroglobin family Erp_C PF06780.6 AJW71015.1 - 0.039 13.8 1.7 1.7 8.4 0.5 2.1 1 1 1 2 2 2 0 Erp protein C-terminus Cob_adeno_trans PF01923.13 AJW71015.1 - 0.042 13.6 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF2262 PF10020.4 AJW71015.1 - 0.082 13.1 0.7 0.12 12.5 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Glycoprotein_B PF00606.13 AJW71017.1 - 0.11 10.5 0.0 0.12 10.3 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Penicillinase_R PF03965.11 AJW71018.1 - 0.0022 18.0 0.7 0.01 15.9 0.1 1.9 1 1 1 2 2 2 1 Penicillinase repressor Response_reg PF00072.19 AJW71019.1 - 2.6e-10 40.3 0.0 5.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain FeoC PF09012.5 AJW71019.1 - 1.9e-05 24.2 1.3 0.00055 19.5 0.6 2.8 2 0 0 2 2 2 1 FeoC like transcriptional regulator zf-Di19 PF05605.7 AJW71019.1 - 0.00048 20.2 2.4 0.0011 19.0 0.4 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding HTH_24 PF13412.1 AJW71019.1 - 0.0037 16.6 1.4 0.012 14.9 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DZR PF12773.2 AJW71019.1 - 0.0083 15.9 15.1 0.56 10.0 1.7 3.0 1 1 2 3 3 3 3 Double zinc ribbon zf-C3HC4_3 PF13920.1 AJW71019.1 - 0.016 14.8 10.8 1.6 8.4 0.3 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FaeA PF04703.7 AJW71019.1 - 0.017 15.3 0.1 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 FaeA-like protein Zn_Tnp_IS1595 PF12760.2 AJW71019.1 - 0.079 12.7 10.2 1.2 8.9 0.1 3.8 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Spt4 PF06093.8 AJW71019.1 - 0.093 12.6 4.8 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger HTH_45 PF14947.1 AJW71019.1 - 0.14 12.0 3.5 0.14 11.9 0.1 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix zinc-ribbons_6 PF07191.7 AJW71019.1 - 0.33 10.7 13.6 0.043 13.6 1.3 3.1 1 1 2 3 3 3 0 zinc-ribbons HypA PF01155.14 AJW71019.1 - 0.57 9.8 13.6 0.27 10.9 0.2 3.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 AJW71019.1 - 2.1 8.4 10.7 10 6.2 3.5 2.5 1 1 1 2 2 2 0 Stc1 domain Pox_vIL-18BP PF05566.7 AJW71019.1 - 2.1 8.3 6.4 37 4.3 0.8 3.2 1 1 2 3 3 3 0 Orthopoxvirus interleukin 18 binding protein Prok-RING_1 PF14446.1 AJW71019.1 - 4.3 7.1 10.4 21 4.9 0.4 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Endonuclease_7 PF02945.10 AJW71019.1 - 7 6.4 7.0 96 2.7 4.9 2.5 1 1 0 1 1 1 0 Recombination endonuclease VII Leu_zip PF15294.1 AJW71020.1 - 0.00084 18.5 4.2 0.00084 18.5 2.9 1.0 1 0 0 1 1 1 1 Leucine zipper FlaC_arch PF05377.6 AJW71020.1 - 0.0024 17.7 2.5 0.0028 17.5 1.7 1.2 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 AJW71020.1 - 0.0039 16.9 6.5 0.0041 16.9 4.5 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding BMFP PF04380.8 AJW71020.1 - 0.0061 16.6 2.1 0.0061 16.6 1.4 1.1 1 0 0 1 1 1 1 Membrane fusogenic activity IFP_35_N PF07334.8 AJW71020.1 - 0.0087 16.0 4.3 0.01 15.7 3.0 1.1 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 PF07716.10 AJW71020.1 - 0.012 15.4 5.2 0.06 13.1 3.6 1.9 1 1 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 AJW71020.1 - 0.015 14.9 1.5 0.018 14.7 0.3 1.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain CENP-F_N PF10481.4 AJW71020.1 - 0.019 14.3 3.0 0.018 14.4 2.1 1.0 1 0 0 1 1 1 0 Cenp-F N-terminal domain DivIC PF04977.10 AJW71020.1 - 0.023 14.1 5.3 0.026 13.9 3.6 1.2 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 AJW71020.1 - 0.027 14.2 2.6 0.033 13.9 1.8 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4200 PF13863.1 AJW71020.1 - 0.03 14.2 4.4 0.032 14.1 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Rho_Binding PF08912.6 AJW71020.1 - 0.031 14.5 4.3 0.035 14.4 3.0 1.1 1 0 0 1 1 1 0 Rho Binding ATG16 PF08614.6 AJW71020.1 - 0.035 13.9 5.0 0.036 13.8 3.4 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DASH_Spc34 PF08657.5 AJW71020.1 - 0.035 13.7 2.9 0.037 13.6 2.0 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 BLOC1_2 PF10046.4 AJW71020.1 - 0.036 14.1 1.7 0.037 14.1 1.2 1.0 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 AJW71020.1 - 0.04 13.8 4.8 0.041 13.8 3.3 1.1 1 0 0 1 1 1 0 bZIP transcription factor PspA_IM30 PF04012.7 AJW71020.1 - 0.042 13.2 1.9 0.043 13.1 1.3 1.0 1 0 0 1 1 1 0 PspA/IM30 family CCDC92 PF14916.1 AJW71020.1 - 0.047 13.2 3.6 0.13 11.8 2.5 1.7 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Shugoshin_N PF07558.6 AJW71020.1 - 0.047 13.4 3.8 0.16 11.6 0.4 2.1 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF4618 PF15397.1 AJW71020.1 - 0.058 12.7 3.1 0.055 12.7 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Microtub_assoc PF07989.6 AJW71020.1 - 0.064 13.0 3.7 0.073 12.9 2.5 1.1 1 0 0 1 1 1 0 Microtubule associated Snapin_Pallidin PF14712.1 AJW71020.1 - 0.068 13.4 1.5 0.074 13.3 1.1 1.0 1 0 0 1 1 1 0 Snapin/Pallidin DUF2968 PF11180.3 AJW71020.1 - 0.07 12.5 1.6 0.073 12.4 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PspB PF06667.7 AJW71020.1 - 0.072 13.0 2.2 0.11 12.4 1.6 1.3 1 1 0 1 1 1 0 Phage shock protein B DivIVA PF05103.8 AJW71020.1 - 0.079 13.0 3.0 0.082 12.9 2.1 1.1 1 0 0 1 1 1 0 DivIVA protein IncA PF04156.9 AJW71020.1 - 0.083 12.4 4.3 0.088 12.4 3.0 1.0 1 0 0 1 1 1 0 IncA protein Ax_dynein_light PF10211.4 AJW71020.1 - 0.092 12.5 3.7 0.089 12.6 2.6 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain DUF2353 PF09789.4 AJW71020.1 - 0.092 11.9 3.3 0.09 12.0 2.3 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Dor1 PF04124.7 AJW71020.1 - 0.096 11.1 2.0 0.099 11.0 1.4 1.0 1 0 0 1 1 1 0 Dor1-like family TBPIP PF07106.8 AJW71020.1 - 0.11 12.0 3.7 0.11 12.0 2.6 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cep57_CLD_2 PF14197.1 AJW71020.1 - 0.11 12.4 4.1 0.096 12.6 1.3 1.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 NBP1 PF08537.5 AJW71020.1 - 0.11 11.6 2.5 0.12 11.5 1.7 1.0 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 MerR-DNA-bind PF09278.6 AJW71020.1 - 0.13 12.6 2.0 0.21 11.9 1.4 1.4 1 1 0 1 1 1 0 MerR, DNA binding Ead_Ea22 PF13935.1 AJW71020.1 - 0.17 12.2 3.0 0.17 12.2 2.1 1.0 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF972 PF06156.8 AJW71020.1 - 0.2 11.9 3.2 0.2 12.0 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) FliD_C PF07195.7 AJW71020.1 - 0.21 10.8 1.1 0.2 10.8 0.8 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus SYCE1 PF15233.1 AJW71020.1 - 0.24 11.3 5.0 0.23 11.3 3.5 1.0 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Fib_alpha PF08702.5 AJW71020.1 - 0.3 11.1 2.1 0.3 11.1 1.4 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 AJW71020.1 - 0.32 11.4 2.4 0.97 9.8 1.6 1.7 1 1 0 1 1 1 0 SlyX PhoU PF01895.14 AJW71020.1 - 0.34 11.3 2.2 0.35 11.3 1.5 1.1 1 0 0 1 1 1 0 PhoU domain CCDC-167 PF15188.1 AJW71020.1 - 0.43 10.5 4.1 0.46 10.4 2.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spc24 PF08286.6 AJW71020.1 - 0.49 10.1 3.2 0.51 10.0 2.2 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Herpes_UL6 PF01763.11 AJW71020.1 - 0.53 8.4 2.7 0.54 8.3 1.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like CALCOCO1 PF07888.6 AJW71020.1 - 0.53 8.5 3.8 0.53 8.5 2.7 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF904 PF06005.7 AJW71020.1 - 0.59 10.4 7.3 0.74 10.1 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 AJW71020.1 - 0.97 9.4 5.8 1.8 8.6 4.0 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF3373 PF11853.3 AJW71020.1 - 1.3 7.4 4.0 1.2 7.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Osmo_CC PF08946.5 AJW71020.1 - 1.3 9.0 7.4 2.2 8.3 5.1 1.5 1 1 0 1 1 1 0 Osmosensory transporter coiled coil Pox_A_type_inc PF04508.7 AJW71020.1 - 5.2 7.1 7.8 1.6e+02 2.4 4.8 3.0 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat Thioredoxin_9 PF14595.1 AJW71022.1 - 0.11 12.0 0.8 0.13 11.8 0.5 1.1 1 0 0 1 1 1 0 Thioredoxin 3D PF06725.6 AJW71023.1 - 8.5e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 3D domain Pox_polyA_pol_C PF12629.2 AJW71023.1 - 0.037 13.7 0.2 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain Omega-toxin PF06357.6 AJW71024.1 - 0.0032 16.9 0.4 0.0049 16.4 0.3 1.2 1 0 0 1 1 1 1 Omega-atracotoxin RST PF12174.3 AJW71024.1 - 0.053 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DNA_primase_lrg PF04104.9 AJW71025.1 - 3.7e-05 23.1 0.6 4.4e-05 22.8 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit OmpH PF03938.9 AJW71025.1 - 0.0083 16.0 1.9 0.01 15.7 1.3 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF1389 PF07146.6 AJW71025.1 - 0.018 14.0 1.1 0.026 13.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1389) DUF2140 PF09911.4 AJW71025.1 - 0.058 12.5 1.4 0.1 11.7 0.4 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) ABC2_membrane_3 PF12698.2 AJW71025.1 - 0.086 11.8 2.6 0.5 9.3 1.8 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein COMPASS-Shg1 PF05205.7 AJW71025.1 - 0.17 12.2 3.9 0.25 11.6 2.3 1.6 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 APP_E2 PF12925.2 AJW71025.1 - 0.26 10.8 4.3 0.34 10.4 2.9 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Tup_N PF08581.5 AJW71025.1 - 0.42 10.8 8.7 0.35 11.0 4.9 1.8 1 1 0 1 1 1 0 Tup N-terminal HMG_box PF00505.14 AJW71025.1 - 1.1 9.5 6.9 0.27 11.5 0.5 2.3 1 1 1 2 2 2 0 HMG (high mobility group) box CPDase PF07823.6 AJW71026.1 - 1.1e-15 57.6 2.9 1.5e-15 57.2 2.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 AJW71026.1 - 0.00061 19.5 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Met_gamma_lyase PF06838.6 AJW71026.1 - 0.014 13.7 0.0 0.014 13.7 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SnoaL_2 PF12680.2 AJW71028.1 - 1.2e-12 48.0 0.0 1.5e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AJW71028.1 - 1.1e-07 31.9 0.0 1.4e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 AJW71028.1 - 1.2e-06 28.0 0.3 3.4e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase LEH PF07858.7 AJW71028.1 - 5.8e-05 23.0 0.1 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_3 PF13474.1 AJW71028.1 - 0.099 12.6 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF897 PF05982.7 AJW71029.1 - 0.036 12.8 0.1 2.8 6.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF897) Cas_Cas1 PF01867.11 AJW71030.1 - 2.6e-44 151.4 0.4 2.6e-43 148.1 0.3 2.0 1 1 0 1 1 1 1 CRISPR associated protein Cas1 DUF3698 PF12479.3 AJW71031.1 - 0.11 12.5 2.1 0.24 11.5 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) YopJ PF03421.11 AJW71032.1 - 0.06 13.2 0.4 0.06 13.2 0.3 1.9 3 0 0 3 3 3 0 YopJ Serine/Threonine acetyltransferase DUF2004 PF09406.5 AJW71032.1 - 0.075 13.0 1.4 2 8.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2004) Phage_RpbA PF10789.4 AJW71034.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA DUF2536 PF10750.4 AJW71035.1 - 0.22 11.1 1.0 0.33 10.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) HxlR PF01638.12 AJW71036.1 - 0.021 14.4 0.2 0.054 13.1 0.1 1.7 2 0 0 2 2 2 0 HxlR-like helix-turn-helix EHN PF06441.7 AJW71036.1 - 0.064 13.1 0.7 0.2 11.5 0.3 2.0 1 1 0 1 1 1 0 Epoxide hydrolase N terminus DUF1436 PF07262.6 AJW71039.1 - 0.00061 19.2 2.8 0.00075 19.0 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1436) GspL_C PF12693.2 AJW71039.1 - 0.0096 15.6 0.7 0.041 13.6 0.0 1.9 1 1 1 2 2 2 1 GspL periplasmic domain DUF3646 PF12362.3 AJW71039.1 - 0.056 13.3 0.7 0.15 11.9 0.5 1.7 1 1 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Vps39_2 PF10367.4 AJW71039.1 - 0.16 12.1 2.6 0.17 12.0 1.3 1.5 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 VWD PF00094.20 AJW71039.1 - 0.28 11.3 1.3 0.51 10.5 0.3 1.5 1 1 0 1 1 1 0 von Willebrand factor type D domain Sipho_Gp157 PF05565.6 AJW71039.1 - 0.53 9.8 7.0 0.28 10.7 2.9 1.8 1 1 0 1 1 1 0 Siphovirus Gp157 SapB_1 PF05184.10 AJW71039.1 - 1.2 9.0 3.3 14 5.6 0.5 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 TPX2 PF06886.6 AJW71039.1 - 2.7 8.0 6.1 4.4 7.4 0.9 2.4 2 1 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Tox-REase-3 PF15647.1 AJW71039.1 - 8.9 6.1 8.2 2 8.2 1.0 2.2 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 3 DNA_pol_B_2 PF03175.8 AJW71040.1 - 3.8e-20 72.0 13.0 5.9e-20 71.3 9.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Mtp PF03821.11 AJW71041.1 - 0.12 11.7 4.3 0.19 11.1 3.0 1.5 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Tmemb_18A PF09771.4 AJW71041.1 - 1.1 9.2 10.4 0.44 10.5 4.3 2.2 1 1 1 2 2 2 0 Transmembrane protein 188 DUF4234 PF14018.1 AJW71041.1 - 1.8 8.3 15.4 0.76 9.5 4.8 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) AAA_21 PF13304.1 AJW71042.1 - 3.4e-17 63.3 40.9 5.7e-14 52.7 6.4 3.4 2 2 1 3 3 3 2 AAA domain AAA_15 PF13175.1 AJW71042.1 - 1.3e-12 47.4 38.5 1.3e-12 47.4 26.7 3.8 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 AJW71042.1 - 5.8e-11 42.0 0.2 3e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AJW71042.1 - 3.8e-06 27.3 42.8 1.1e-05 25.8 18.6 3.7 2 2 0 2 2 2 1 AAA domain HNH PF01844.18 AJW71043.1 - 7.5e-11 41.7 5.7 1.7e-10 40.5 3.9 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.1 AJW71043.1 - 7.2e-07 28.7 0.6 5.8e-06 25.8 0.2 2.6 2 0 0 2 2 2 1 HNH endonuclease HNH_2 PF13391.1 AJW71043.1 - 4.9e-05 23.0 1.2 0.00011 21.8 0.8 1.6 1 0 0 1 1 1 1 HNH endonuclease RgpF PF05045.7 AJW71043.1 - 0.0065 15.0 1.0 0.011 14.3 0.7 1.4 1 0 0 1 1 1 1 Rhamnan synthesis protein F Auto_anti-p27 PF06677.7 AJW71043.1 - 0.039 13.7 2.1 0.043 13.5 0.1 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NERD PF08378.6 AJW71045.1 - 2e-13 50.5 0.4 4.5e-13 49.4 0.0 1.9 2 1 0 2 2 2 1 Nuclease-related domain Imm45 PF15603.1 AJW71045.1 - 0.0054 16.8 0.7 0.0054 16.8 0.5 2.5 3 1 0 3 3 3 1 Immunity protein 45 DUF4143 PF13635.1 AJW71045.1 - 0.011 15.8 1.9 0.034 14.3 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4143) SAS4 PF15460.1 AJW71045.1 - 3.4 7.6 7.0 2.4 8.0 2.0 2.3 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 HTH_45 PF14947.1 AJW71046.1 - 0.0099 15.6 0.6 0.0099 15.6 0.4 2.7 3 0 0 3 3 3 1 Winged helix-turn-helix zf-FCS PF06467.9 AJW71047.1 - 0.019 14.6 2.3 0.86 9.2 0.1 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif PyrI_C PF02748.10 AJW71047.1 - 0.03 13.7 2.1 0.32 10.4 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.1 AJW71047.1 - 0.04 13.5 2.5 5.6 6.7 0.0 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.2 AJW71047.1 - 0.071 12.9 0.4 7 6.5 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon DiS_P_DiS PF06750.8 AJW71047.1 - 0.081 12.7 1.0 9.4 6.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Thioredoxin_3 PF13192.1 AJW71047.1 - 0.087 12.6 0.5 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain DUF2024 PF09630.5 AJW71047.1 - 0.18 11.5 1.7 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Sgf11 PF08209.6 AJW71047.1 - 0.34 10.2 9.7 1.6 8.0 0.2 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-HC5HC2H PF13771.1 AJW71047.1 - 0.41 10.8 5.1 0.41 10.8 0.6 2.4 2 1 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 AJW71047.1 - 0.59 9.9 5.2 11 5.8 0.5 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.1 AJW71047.1 - 0.78 9.4 4.5 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain zinc_ribbon_5 PF13719.1 AJW71047.1 - 1.5 8.5 8.6 0.62 9.6 0.9 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJW71047.1 - 3.7 7.3 9.1 1.4 8.6 1.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 AJW71047.1 - 6.1 6.6 8.5 7.2 6.4 0.4 2.9 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 Pentapeptide_3 PF13576.1 AJW71048.1 - 2.7e-09 36.7 32.6 3.9e-05 23.4 4.3 5.4 2 1 3 5 5 5 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 AJW71048.1 - 0.00068 19.3 16.6 0.018 14.8 2.1 3.6 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 AJW71048.1 - 0.0043 16.2 1.8 0.92 8.8 0.2 4.5 4 2 0 4 4 4 1 Pentapeptide repeats (8 copies) Phage_integrase PF00589.17 AJW71049.1 - 7.2e-15 55.0 1.0 1.1e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family DZR PF12773.2 AJW71049.1 - 0.024 14.4 0.7 0.068 12.9 0.2 1.8 2 0 0 2 2 2 0 Double zinc ribbon NUC130_3NT PF08158.7 AJW71049.1 - 0.09 13.0 0.1 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 NUC130/3NT domain CitX PF03802.9 AJW71049.1 - 0.14 11.5 5.0 0.67 9.3 1.6 2.2 2 0 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DUF2309 PF10070.4 AJW71049.1 - 0.17 9.9 2.4 0.13 10.3 0.8 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF1672 PF07901.6 AJW71049.1 - 3.9 6.3 9.2 3.2 6.6 5.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) DUF1816 PF08846.5 AJW71051.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) zf-B_box PF00643.19 AJW71051.1 - 0.32 10.9 0.1 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 B-box zinc finger AMNp_N PF10423.4 AJW71052.1 - 0.043 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Sec23_helical PF04815.10 AJW71052.1 - 0.17 11.3 0.6 0.42 10.0 0.1 1.9 2 0 0 2 2 2 0 Sec23/Sec24 helical domain ALIX_LYPXL_bnd PF13949.1 AJW71053.1 - 0.00081 18.4 1.7 0.0012 17.9 1.2 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1469 PF07332.6 AJW71053.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) OMS28_porin PF03532.8 AJW71053.1 - 0.04 13.0 0.5 0.28 10.1 0.0 2.0 2 0 0 2 2 2 0 OMS28 porin DUF2140 PF09911.4 AJW71053.1 - 0.07 12.2 0.4 0.16 11.0 0.1 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF4375 PF14300.1 AJW71053.1 - 0.12 12.3 1.4 0.25 11.3 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) BenE PF03594.8 AJW71053.1 - 0.15 10.6 1.8 0.21 10.0 1.3 1.1 1 0 0 1 1 1 0 Benzoate membrane transport protein Orbi_VP5 PF00901.12 AJW71053.1 - 0.21 9.7 3.2 0.27 9.3 2.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF3464 PF11947.3 AJW71053.1 - 0.45 9.9 4.9 0.52 9.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Rho_Binding PF08912.6 AJW71053.1 - 0.95 9.8 0.1 0.95 9.8 0.1 2.3 2 0 0 2 2 2 0 Rho Binding 4HB_MCP_1 PF12729.2 AJW71053.1 - 2.2 7.6 8.5 8.4 5.7 0.1 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DNA_pol_B_2 PF03175.8 AJW71054.1 - 6.6e-14 51.4 15.1 2.5e-13 49.4 10.5 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 AJW71054.1 - 0.63 9.8 5.3 2.4 7.9 3.7 2.0 1 1 0 1 1 1 0 RNase_H superfamily GspL_C PF12693.2 AJW71055.1 - 0.00045 20.0 0.2 0.00056 19.7 0.1 1.1 1 0 0 1 1 1 1 GspL periplasmic domain Helicase_IV_N PF12462.3 AJW71055.1 - 0.013 15.1 1.5 0.016 14.8 1.0 1.3 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Nup84_Nup100 PF04121.8 AJW71055.1 - 0.024 12.3 0.4 0.026 12.2 0.3 1.0 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 DUF1390 PF07150.6 AJW71055.1 - 0.058 12.7 2.4 0.066 12.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Vps39_2 PF10367.4 AJW71055.1 - 0.067 13.3 4.4 0.3 11.2 1.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 RasGAP_C PF03836.10 AJW71055.1 - 0.11 12.1 10.0 3 7.5 6.9 2.1 1 1 0 1 1 1 0 RasGAP C-terminus Myb_DNA-bind_3 PF12776.2 AJW71055.1 - 0.34 11.5 3.8 0.59 10.8 2.6 1.4 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF2458 PF10454.4 AJW71055.1 - 0.41 10.5 6.6 0.52 10.1 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF1280 PF06918.9 AJW71055.1 - 0.67 9.1 4.6 0.78 8.9 2.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1280) DUF342 PF03961.8 AJW71055.1 - 2 6.7 7.4 2.2 6.5 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LepA_C PF06421.7 AJW71055.1 - 4.1 7.3 9.2 3 7.7 5.3 1.6 1 1 0 1 1 1 0 GTP-binding protein LepA C-terminus RBDV_coat PF06593.6 AJW71057.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein Mrr_N PF14338.1 AJW71058.1 - 3.8e-20 71.7 0.4 1.2e-19 70.1 0.3 1.9 1 0 0 1 1 1 1 Mrr N-terminal domain HTH_45 PF14947.1 AJW71058.1 - 0.062 13.1 3.0 0.15 11.9 0.3 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix N6_N4_Mtase PF01555.13 AJW71059.1 - 1.2e-28 100.2 0.2 8.1e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Methyltransf_26 PF13659.1 AJW71059.1 - 2.1e-14 53.5 0.0 3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 AJW71059.1 - 4.9e-05 22.7 0.0 7.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 AJW71059.1 - 5.4e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW71059.1 - 0.0014 19.2 0.0 0.0043 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 AJW71059.1 - 0.0044 16.6 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 AJW71059.1 - 0.066 13.7 0.0 19 5.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.5 AJW71059.1 - 0.082 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF911 PF06023.7 AJW71060.1 - 3.1e-09 36.4 0.0 3.4e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) DUF911 PF06023.7 AJW71061.1 - 9.5e-29 100.5 0.0 1.2e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) DUF1091 PF06477.8 AJW71061.1 - 0.015 15.7 1.3 0.095 13.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) DUF3135 PF11333.3 AJW71062.1 - 0.051 13.7 1.3 3.1 8.0 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) HTH_22 PF13309.1 AJW71062.1 - 0.088 12.5 0.0 0.29 10.9 0.0 2.0 1 0 0 1 1 1 0 HTH domain DUF2791 PF10923.3 AJW71063.1 - 7.8e-07 28.0 0.5 0.0081 14.8 0.1 2.2 2 0 0 2 2 2 2 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.1 AJW71063.1 - 1.2e-06 28.7 0.1 5.4e-05 23.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AJW71063.1 - 5.6e-06 26.2 2.2 8e-06 25.7 1.6 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 AJW71063.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 AJW71063.1 - 0.0026 16.6 0.3 0.0053 15.6 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 AJW71063.1 - 0.0034 16.4 0.3 0.0069 15.4 0.1 1.5 1 1 0 1 1 1 1 KAP family P-loop domain Bac_DnaA PF00308.13 AJW71063.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein Kinesin PF00225.18 AJW71063.1 - 0.011 14.5 0.0 0.035 12.7 0.0 1.8 2 0 0 2 2 2 0 Kinesin motor domain YppF PF14178.1 AJW71063.1 - 0.076 12.5 4.2 1.3 8.5 0.6 2.9 2 1 1 3 3 3 0 YppF-like protein Cas_Cas1 PF01867.11 AJW71065.1 - 7.7e-50 169.5 0.3 1e-49 169.1 0.2 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 AnfG_VnfG PF03139.10 AJW71065.1 - 0.058 13.1 0.5 0.17 11.6 0.2 1.8 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit V-ATPase_G PF03179.10 AJW71066.1 - 0.04 14.1 0.3 0.044 14.0 0.2 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Erp_C PF06780.6 AJW71066.1 - 0.082 12.7 0.6 0.098 12.4 0.4 1.1 1 0 0 1 1 1 0 Erp protein C-terminus GrpE PF01025.14 AJW71066.1 - 0.16 11.5 1.1 0.19 11.2 0.7 1.1 1 0 0 1 1 1 0 GrpE DUF3373 PF11853.3 AJW71066.1 - 0.19 10.2 1.4 0.2 10.1 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) GTP_EFTU PF00009.22 AJW71067.1 - 3.7e-57 192.8 0.6 6.2e-57 192.0 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AJW71067.1 - 1.7e-27 95.3 0.1 7.3e-27 93.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 AJW71067.1 - 1.8e-20 72.5 0.0 6.6e-20 70.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 AJW71067.1 - 1.9e-20 72.4 0.3 6.9e-20 70.6 0.2 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AJW71067.1 - 1.2e-13 50.9 0.1 4.3e-13 49.1 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 AJW71067.1 - 0.044 13.0 0.0 0.16 11.1 0.0 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit RNR_N PF08343.5 AJW71067.1 - 0.15 11.9 0.1 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal SIS PF01380.17 AJW71068.1 - 3.3e-07 29.9 2.6 0.0037 16.8 0.0 3.1 2 1 0 2 2 2 2 SIS domain DUF3028 PF11229.3 AJW71069.1 - 0.11 10.7 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) DUF4345 PF14248.1 AJW71070.1 - 0.00013 21.3 0.2 0.00017 21.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) TMEM51 PF15345.1 AJW71070.1 - 0.00041 20.1 0.1 0.00046 19.9 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 Tetraspannin PF00335.15 AJW71070.1 - 0.019 14.2 1.5 0.024 13.9 1.1 1.0 1 0 0 1 1 1 0 Tetraspanin family Rnf-Nqr PF02508.9 AJW71070.1 - 0.023 14.3 0.2 0.043 13.4 0.0 1.5 2 0 0 2 2 2 0 Rnf-Nqr subunit, membrane protein NfeD PF01957.13 AJW71070.1 - 0.025 14.7 1.7 0.092 12.8 1.2 1.7 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF1049 PF06305.6 AJW71070.1 - 0.027 13.9 0.0 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) UPF0104 PF03706.8 AJW71070.1 - 0.032 13.5 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF4064 PF13273.1 AJW71070.1 - 0.037 14.1 1.9 0.05 13.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3098 PF11297.3 AJW71070.1 - 0.05 13.3 0.8 2.7 7.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Gram_pos_anchor PF00746.16 AJW71070.1 - 0.053 13.3 2.2 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Gram positive anchor DUF2910 PF11139.3 AJW71070.1 - 0.07 12.2 0.3 0.1 11.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) Neurensin PF14927.1 AJW71070.1 - 0.13 11.6 0.2 0.18 11.1 0.1 1.3 1 1 0 1 1 1 0 Neurensin DUF4097 PF13349.1 AJW71070.1 - 0.2 11.1 3.7 4.9 6.6 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4097) EphA2_TM PF14575.1 AJW71070.1 - 0.24 11.8 0.7 2.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 AJW71070.1 - 0.33 11.1 1.9 18 5.6 0.0 2.2 2 0 0 2 2 2 0 Virus attachment protein p12 family SdpI PF13630.1 AJW71070.1 - 5.9 6.6 5.8 27 4.5 4.0 1.8 1 1 0 1 1 1 0 SdpI/YhfL protein family DUF77 PF01910.12 AJW71073.1 - 6.6e-25 86.6 1.9 7.4e-25 86.4 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 NanE PF04131.9 AJW71073.1 - 0.06 12.3 1.1 0.068 12.1 0.8 1.1 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Radical_SAM PF04055.16 AJW71074.1 - 9.4e-16 58.4 0.0 2.1e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 AJW71074.1 - 0.032 14.3 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_14 PF13394.1 AJW71074.1 - 0.045 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain TPR_11 PF13414.1 AJW71075.1 - 4.2e-29 100.0 10.8 3.8e-12 45.6 2.3 2.7 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 AJW71075.1 - 8.1e-27 91.7 12.1 3.3e-07 29.6 0.7 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 AJW71075.1 - 4.2e-24 84.2 15.4 1.2e-08 34.6 1.4 3.0 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 AJW71075.1 - 2.7e-23 79.9 8.0 3.4e-05 23.4 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 AJW71075.1 - 4.8e-18 65.3 1.8 3.8e-09 36.9 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJW71075.1 - 4.6e-15 54.7 2.4 0.0041 17.6 0.0 4.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AJW71075.1 - 8.9e-14 50.4 5.7 8.6e-05 22.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 AJW71075.1 - 6.9e-13 47.3 1.9 0.0033 17.1 0.1 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 AJW71075.1 - 1.7e-11 44.2 9.3 2.5e-06 27.7 0.5 3.4 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 AJW71075.1 - 1.2e-10 40.3 10.5 0.11 12.3 0.5 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 AJW71075.1 - 3.6e-10 39.5 0.1 6.1e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AJW71075.1 - 1.9e-09 37.5 8.4 2.7e-06 27.3 0.4 2.2 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 AJW71075.1 - 7.7e-09 35.3 3.2 0.97 9.3 0.0 4.2 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 AJW71075.1 - 9.7e-09 34.8 7.6 0.044 13.6 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 AJW71075.1 - 3.7e-06 26.6 1.1 0.074 13.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AJW71075.1 - 1.1e-05 25.5 10.6 3.6 8.2 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 AJW71075.1 - 2.9e-05 23.9 0.1 1.8 8.3 0.0 3.5 2 2 1 3 3 3 2 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 AJW71075.1 - 0.0001 22.2 0.4 0.095 12.7 0.0 2.8 1 1 1 2 2 2 2 Tetratrico peptide repeat Fis1_TPR_C PF14853.1 AJW71075.1 - 0.00057 19.7 5.1 0.9 9.4 0.0 4.4 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 AJW71075.1 - 0.00063 18.6 1.5 0.11 11.2 0.0 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 PPR_2 PF13041.1 AJW71075.1 - 0.013 15.4 0.3 15 5.6 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family BRO1 PF03097.13 AJW71075.1 - 0.014 14.1 0.6 0.019 13.7 0.4 1.3 1 0 0 1 1 1 0 BRO1-like domain TOM20_plant PF06552.7 AJW71075.1 - 0.027 14.0 0.9 6.5 6.2 0.0 2.7 1 1 2 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 4HB_MCP_1 PF12729.2 AJW71075.1 - 0.027 13.8 0.3 0.027 13.8 0.2 2.2 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction SPO22 PF08631.5 AJW71075.1 - 0.049 12.7 2.2 2.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like PPR PF01535.15 AJW71075.1 - 0.054 13.4 1.8 3.9 7.6 0.0 3.6 5 0 0 5 5 3 0 PPR repeat PSD5 PF07637.6 AJW71075.1 - 0.068 13.2 0.1 0.7 9.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1595) PPR_1 PF12854.2 AJW71075.1 - 0.23 10.9 0.7 5.9 6.4 0.0 3.0 3 0 0 3 3 3 0 PPR repeat SHNi-TPR PF10516.4 AJW71075.1 - 3.2 7.0 6.0 33 3.8 0.1 3.9 4 1 0 4 4 4 0 SHNi-TPR TPR_1 PF00515.23 AJW71076.1 - 2.3e-19 68.0 0.1 8.2e-10 37.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 AJW71076.1 - 4.1e-18 64.7 0.0 4.9e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 AJW71076.1 - 6.8e-18 63.0 0.0 1.6e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AJW71076.1 - 2.8e-13 48.6 0.1 2e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 AJW71076.1 - 6.3e-10 38.4 1.4 1.7e-06 27.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 AJW71076.1 - 9.8e-10 38.1 0.0 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 AJW71076.1 - 2.6e-09 36.1 0.0 0.0026 17.4 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 AJW71076.1 - 6.6e-09 35.5 0.0 0.00034 20.4 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 AJW71076.1 - 7.5e-09 36.0 0.0 9.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 AJW71076.1 - 8e-09 35.3 0.0 0.00035 20.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AJW71076.1 - 1e-07 32.1 0.0 1.2e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 AJW71076.1 - 0.0028 17.5 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AJW71076.1 - 0.0031 17.6 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AJW71076.1 - 0.0079 16.5 0.0 4.7 7.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 AJW71076.1 - 0.013 15.6 0.0 0.015 15.5 0.0 1.0 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation PPR PF01535.15 AJW71076.1 - 0.014 15.3 0.2 4 7.6 0.0 2.5 2 0 0 2 2 2 0 PPR repeat DUF3856 PF12968.2 AJW71076.1 - 0.017 14.9 0.0 0.079 12.7 0.0 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 AJW71076.1 - 0.031 14.3 0.0 1.7 8.7 0.0 2.0 1 1 0 2 2 2 0 Tetratrico peptide repeat Fis1_TPR_C PF14853.1 AJW71076.1 - 0.034 14.0 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 AJW71076.1 - 0.037 14.3 0.0 0.17 12.1 0.0 1.7 1 1 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.13 AJW71076.1 - 0.044 13.6 0.0 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.3 AJW71076.1 - 0.078 11.7 0.0 0.092 11.4 0.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MAS20 PF02064.10 AJW71076.1 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 MAS20 protein import receptor HTH_AsnC-type PF13404.1 AJW71077.1 - 7.6e-12 44.5 1.3 1.2e-11 43.9 0.9 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AJW71077.1 - 1.5e-11 43.5 3.1 3e-11 42.5 1.4 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 AJW71077.1 - 1.3e-10 40.7 0.3 2.2e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 AsnC family HTH_11 PF08279.7 AJW71077.1 - 9.4e-05 21.9 1.4 0.00015 21.3 0.7 1.6 1 1 0 1 1 1 1 HTH domain HTH_20 PF12840.2 AJW71077.1 - 0.0039 16.9 0.1 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DDRGK PF09756.4 AJW71077.1 - 0.0081 15.5 0.5 0.019 14.3 0.1 1.7 1 1 1 2 2 2 1 DDRGK domain MarR_2 PF12802.2 AJW71077.1 - 0.018 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 AJW71077.1 - 0.022 14.5 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF294_C PF10335.4 AJW71077.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain MarR PF01047.17 AJW71077.1 - 0.038 13.6 0.3 0.071 12.8 0.2 1.5 1 0 0 1 1 1 0 MarR family HxlR PF01638.12 AJW71077.1 - 0.046 13.3 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_10 PF04967.7 AJW71077.1 - 0.068 12.7 0.8 0.14 11.7 0.2 1.8 2 0 0 2 2 2 0 HTH DNA binding domain DnaJ PF00226.26 AJW71078.1 - 2.4e-23 81.6 1.9 5.4e-23 80.5 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain O-ag_pol_Wzy PF14296.1 AJW71078.1 - 0.062 11.8 0.5 0.088 11.3 0.4 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF2899 PF11449.3 AJW71078.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) YMF19 PF02326.10 AJW71078.1 - 0.22 12.1 1.3 9.2 6.9 0.1 2.4 1 1 0 2 2 2 0 Plant ATP synthase F0 HD PF01966.17 AJW71080.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 HD domain PDEase_I PF00233.14 AJW71080.1 - 0.027 14.2 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase UPF0565 PF10561.4 AJW71080.1 - 0.033 13.0 0.1 0.093 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 FAD-oxidase_C PF02913.14 AJW71081.1 - 2.8e-40 138.2 0.0 3.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AJW71081.1 - 4.2e-30 104.0 0.0 8.8e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Cytokin-bind PF09265.5 AJW71081.1 - 0.012 14.7 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF1425 PF07233.7 AJW71082.1 - 0.024 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) Transglut_C PF00927.17 AJW71082.1 - 0.052 13.5 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain GFA PF04828.9 AJW71083.1 - 0.3 11.0 2.4 1.7 8.6 1.7 1.8 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.1 AJW71083.1 - 0.52 10.0 3.8 1.8 8.2 2.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.1 AJW71083.1 - 1 9.1 3.7 7 6.4 2.5 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJW71083.1 - 1.3 8.7 3.6 9.7 5.8 2.5 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-CHY PF05495.7 AJW71085.1 - 0.022 14.9 0.7 0.024 14.7 0.5 1.0 1 0 0 1 1 1 0 CHY zinc finger XPA_N PF01286.13 AJW71085.1 - 0.022 14.4 3.7 0.44 10.2 2.7 2.0 1 1 0 1 1 1 0 XPA protein N-terminal LIM PF00412.17 AJW71085.1 - 0.051 13.6 1.9 0.062 13.3 1.3 1.2 1 0 0 1 1 1 0 LIM domain DZR PF12773.2 AJW71085.1 - 0.058 13.2 0.8 0.072 12.9 0.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 AJW71085.1 - 0.071 12.7 0.1 0.094 12.3 0.0 1.3 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 AJW71085.1 - 0.19 11.6 2.2 0.3 11.0 1.6 1.3 1 1 0 1 1 1 0 Zinc ribbon domain DUF2082 PF09855.4 AJW71085.1 - 1 9.2 4.0 2.3 8.1 0.2 2.0 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TFIIS_C PF01096.13 AJW71085.1 - 1.1 8.9 3.4 15 5.2 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CCHC PF00098.18 AJW71085.1 - 1.3 9.0 4.0 1.2 9.1 0.3 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.1 AJW71086.1 - 1.1e-05 24.4 0.7 3e-05 23.0 0.5 1.8 1 0 0 1 1 1 1 zinc-ribbon domain CBM_14 PF01607.19 AJW71086.1 - 4.1e-05 23.4 0.7 0.28 11.1 0.0 2.4 1 1 1 2 2 2 2 Chitin binding Peritrophin-A domain DZR PF12773.2 AJW71086.1 - 0.0001 22.0 0.4 0.00024 20.8 0.3 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 AJW71086.1 - 0.00012 21.4 1.2 0.00012 21.4 0.8 2.1 3 0 0 3 3 3 1 zinc-ribbon domain COX16 PF14138.1 AJW71086.1 - 0.015 15.4 0.1 0.076 13.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Pacifastin_I PF05375.8 AJW71086.1 - 0.025 14.0 1.0 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) zf-DHHC PF01529.15 AJW71086.1 - 0.052 12.9 0.4 0.092 12.1 0.3 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1980 PF09323.5 AJW71086.1 - 0.053 13.2 0.4 0.053 13.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2592 PF10766.4 AJW71086.1 - 0.074 12.4 2.8 0.13 11.5 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) UPF0547 PF10571.4 AJW71086.1 - 0.16 11.6 1.1 0.37 10.5 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Response_reg PF00072.19 AJW71087.1 - 6.8e-16 58.2 0.2 9.4e-16 57.8 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain 2-Hacid_dh_C PF02826.14 AJW71087.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Response_reg PF00072.19 AJW71089.1 - 1e-15 57.6 0.1 1.2e-15 57.5 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 AJW71089.1 - 0.0065 16.3 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain AFOR_C PF01314.13 AJW71089.1 - 0.081 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 DUF1176 PF06674.6 AJW71092.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Sod_Fe_C PF02777.13 AJW71093.1 - 2.3e-40 136.7 2.0 3.8e-40 136.0 1.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AJW71093.1 - 5.1e-23 81.1 1.2 6.7e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HTH_20 PF12840.2 AJW71094.1 - 0.0026 17.5 0.0 0.0083 15.9 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 AJW71094.1 - 0.0053 16.3 0.4 0.03 13.9 0.2 2.3 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family PadR PF03551.9 AJW71094.1 - 0.01 15.5 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family TrmB PF01978.14 AJW71094.1 - 0.037 13.7 0.4 0.67 9.6 0.1 2.7 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 AJW71094.1 - 0.07 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain cwf21 PF08312.7 AJW71094.1 - 0.23 11.3 4.1 3.4 7.5 0.0 2.7 2 1 0 2 2 2 0 cwf21 domain HTH_24 PF13412.1 AJW71094.1 - 0.32 10.4 4.0 11 5.5 1.9 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF310 PF03750.8 AJW71094.1 - 2 8.6 4.7 2.3 8.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF310) SNF2_N PF00176.18 AJW71095.1 - 1.4e-39 135.7 0.1 2.4e-39 134.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AJW71095.1 - 1.6e-08 34.3 0.1 6.3e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AJW71095.1 - 1.4e-07 31.1 0.0 5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AJW71095.1 - 1.8e-06 27.8 3.2 6.6e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3380 PF11860.3 AJW71095.1 - 0.086 12.8 0.5 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3380) HGD-D PF06050.8 AJW71095.1 - 0.12 11.1 1.4 1.3 7.7 0.0 2.3 2 1 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component PTPlike_phytase PF14566.1 AJW71095.1 - 0.2 11.7 1.0 0.47 10.4 0.7 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Hyccin PF09790.4 AJW71096.1 - 0.012 14.4 0.2 0.017 14.0 0.1 1.1 1 0 0 1 1 1 0 Hyccin CarboxypepD_reg PF13620.1 AJW71097.1 - 0.00021 21.2 0.1 0.00042 20.3 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain UVR PF02151.14 AJW71097.1 - 0.03 13.8 0.2 0.03 13.8 0.1 2.5 3 0 0 3 3 3 0 UvrB/uvrC motif ArsC PF03960.10 AJW71098.1 - 2.4e-23 82.3 0.4 2.5e-23 82.2 0.3 1.0 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.19 AJW71098.1 - 0.0019 18.1 0.9 0.013 15.5 0.2 2.0 1 1 1 2 2 2 1 Glutaredoxin SapB_1 PF05184.10 AJW71098.1 - 0.16 11.8 0.5 4.1 7.3 0.1 2.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 Pox_VLTF3 PF04947.9 AJW71100.1 - 0.039 13.4 1.7 0.042 13.3 0.2 1.6 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Orthopox_A36R PF05950.6 AJW71100.1 - 0.06 13.2 3.3 1.7 8.5 0.3 2.2 1 1 1 2 2 2 0 Orthopoxvirus A36R protein DUF2196 PF09962.4 AJW71101.1 - 1.4e-29 101.6 1.6 1.5e-29 101.5 1.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Molybdop_Fe4S4 PF04879.11 AJW71102.1 - 0.018 14.8 7.8 0.42 10.4 0.6 2.2 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain DNA_RNApol_7kD PF03604.8 AJW71102.1 - 0.03 13.7 17.1 0.45 10.0 2.9 2.9 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 AJW71102.1 - 0.064 13.0 13.8 0.51 10.2 2.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF4001 PF13165.1 AJW71102.1 - 0.11 12.1 8.9 1.2 8.8 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4001) zinc_ribbon_6 PF14599.1 AJW71102.1 - 0.14 12.0 11.9 0.36 10.6 1.3 2.9 2 2 1 3 3 3 0 Zinc-ribbon Stig1 PF04885.8 AJW71102.1 - 0.18 12.0 4.7 6.8 6.8 0.3 2.5 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 LIM PF00412.17 AJW71102.1 - 0.28 11.2 13.4 1.8 8.7 2.1 2.2 2 0 0 2 2 2 0 LIM domain DUF1059 PF06348.6 AJW71102.1 - 0.37 10.6 3.9 3.5 7.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Zn-ribbon_8 PF09723.5 AJW71102.1 - 0.87 9.5 17.7 1.3 8.9 3.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.17 AJW71102.1 - 1.4 8.7 11.5 3.1 7.5 1.5 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 AJW71102.1 - 2.7 7.7 10.3 2.6 7.7 0.3 3.0 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like HypA PF01155.14 AJW71102.1 - 6.6 6.4 10.1 3.8 7.2 0.8 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-UBR PF02207.15 AJW71102.1 - 6.7 6.5 16.6 8.7 6.1 3.1 2.5 2 2 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ZZ PF00569.12 AJW71102.1 - 9.5 5.8 17.3 3.8 7.1 0.2 3.9 4 0 0 4 4 4 0 Zinc finger, ZZ type BPD_transp_1 PF00528.17 AJW71103.1 - 1.9e-35 122.0 22.0 1.9e-35 122.0 15.2 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Claudin_2 PF13903.1 AJW71103.1 - 7.4 6.2 8.6 0.069 12.8 0.2 2.0 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction BPD_transp_1 PF00528.17 AJW71104.1 - 2.4e-25 89.1 9.6 2.4e-25 89.1 6.7 2.3 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.2 AJW71104.1 - 6.2e-06 25.4 0.1 2.5e-05 23.5 0.1 2.0 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C zf-NADH-PPase PF09297.6 AJW71106.1 - 0.013 14.9 3.1 0.041 13.4 0.5 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF2422 PF10337.4 AJW71106.1 - 0.055 12.2 0.2 0.067 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Peptidase_C74 PF12387.3 AJW71106.1 - 0.062 12.4 1.3 0.086 11.9 0.9 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase TF_Zn_Ribbon PF08271.7 AJW71106.1 - 0.41 10.0 2.2 1.1 8.5 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 AJW71106.1 - 0.77 10.0 5.2 5.5 7.3 3.6 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 AJW71106.1 - 0.95 9.4 4.1 4 7.4 2.8 1.9 1 1 0 1 1 1 0 Zinc ribbon domain TFIIS_C PF01096.13 AJW71106.1 - 1.4 8.6 3.7 19 4.9 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-HIT PF04438.11 AJW71106.1 - 1.6 8.4 4.9 3.3 7.4 3.4 1.5 1 1 0 1 1 1 0 HIT zinc finger Prok-JAB PF14464.1 AJW71107.1 - 4.6e-12 45.4 0.0 6.2e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 AJW71107.1 - 0.00044 19.9 0.1 0.0023 17.6 0.0 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.10 AJW71107.1 - 0.015 14.9 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain APG6 PF04111.7 AJW71108.1 - 3.8e-05 22.8 27.7 0.00012 21.1 11.4 2.3 2 0 0 2 2 2 2 Autophagy protein Apg6 Laminin_II PF06009.7 AJW71108.1 - 0.0096 15.6 1.4 0.0096 15.6 1.0 4.7 2 1 3 5 5 5 1 Laminin Domain II Hemerythrin PF01814.18 AJW71108.1 - 0.027 14.6 0.2 0.76 9.9 0.0 2.7 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain AAA_13 PF13166.1 AJW71108.1 - 0.03 12.8 43.7 0.043 12.2 10.9 2.1 1 1 1 2 2 2 0 AAA domain DUF342 PF03961.8 AJW71108.1 - 0.099 11.0 30.2 0.44 8.8 11.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.2 AJW71108.1 - 0.13 12.1 27.7 0.36 10.6 9.7 2.9 2 1 0 2 2 2 0 Tropomyosin like Laminin_I PF06008.9 AJW71108.1 - 0.16 11.2 28.9 0.017 14.4 1.6 3.2 3 1 0 3 3 3 0 Laminin Domain I Mod_r PF07200.8 AJW71108.1 - 0.17 11.8 26.1 0.15 11.9 9.4 3.8 3 2 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.3 AJW71108.1 - 0.87 8.7 21.7 0.5 9.5 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 AJW71108.1 - 0.9 8.1 35.4 0.25 9.9 11.2 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF745 PF05335.8 AJW71108.1 - 5.1 6.5 13.2 1.5 8.2 3.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF745) TMF_DNA_bd PF12329.3 AJW71108.1 - 5.2 6.9 33.8 0.021 14.6 8.4 4.9 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF1212 PF06738.7 AJW71108.1 - 6.4 6.1 5.5 6.5 6.1 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1212) NPV_P10 PF05531.7 AJW71108.1 - 8 6.7 33.2 0.77 10.0 0.3 6.1 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DMPK_coil PF08826.5 AJW71108.1 - 9.5 6.2 16.8 1.7 8.6 3.2 3.5 3 0 0 3 3 3 0 DMPK coiled coil domain like Reo_sigmaC PF04582.7 AJW71108.1 - 9.6 5.2 22.0 7.9 5.5 3.2 3.6 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Polyketide_cyc2 PF10604.4 AJW71109.1 - 1.3e-14 54.5 0.0 1.5e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AJW71109.1 - 0.0032 17.4 0.0 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COX6A PF02046.10 AJW71109.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa DUF1206 PF06724.6 AJW71110.1 - 0.32 10.7 0.2 0.32 10.7 0.1 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) Phi-29_GP3 PF05435.6 AJW71113.1 - 0.1 11.8 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 AsnC_trans_reg PF01037.16 AJW71114.1 - 1.4e-10 40.7 0.2 1.7e-10 40.4 0.1 1.0 1 0 0 1 1 1 1 AsnC family LAGLIDADG_WhiA PF14527.1 AJW71114.1 - 0.058 13.2 0.2 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Nitroreductase PF00881.19 AJW71115.1 - 1.5e-30 106.1 0.0 2.6e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family A2L_zn_ribbon PF08792.5 AJW71116.1 - 0.3 10.5 0.4 0.3 10.5 0.3 2.1 2 1 0 2 2 2 0 A2L zinc ribbon domain zf-primase PF09329.6 AJW71116.1 - 0.49 10.0 7.0 0.75 9.4 0.3 2.2 1 1 1 2 2 2 0 Primase zinc finger Apo-CIII PF05778.7 AJW71119.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) SAC3 PF12209.3 AJW71120.1 - 0.0008 19.4 0.5 0.0084 16.2 0.1 2.1 1 1 1 2 2 2 1 Leucine permease transcriptional regulator helical domain Cauli_AT PF03233.8 AJW71120.1 - 0.02 14.6 1.2 0.022 14.4 0.8 1.2 1 0 0 1 1 1 0 Aphid transmission protein PTPA PF03095.10 AJW71120.1 - 0.04 13.0 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein XPG_I PF00867.13 AJW71121.1 - 3e-22 78.4 0.0 6.7e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AJW71121.1 - 1.8e-21 76.2 0.0 8.5e-21 74.1 0.0 2.0 1 1 1 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 AJW71121.1 - 0.00016 21.8 0.0 0.00045 20.3 0.0 1.8 1 1 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Mg296 PF09644.5 AJW71121.1 - 0.13 12.1 2.3 0.28 11.0 1.6 1.5 1 0 0 1 1 1 0 Mg296 protein PAS_9 PF13426.1 AJW71122.1 - 3.3e-11 43.4 0.0 4.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 AJW71122.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 AJW71122.1 - 0.00017 21.6 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 AJW71122.1 - 0.00049 20.1 0.0 0.00062 19.7 0.0 1.1 1 0 0 1 1 1 1 PAS fold MRP-S27 PF10037.4 AJW71122.1 - 0.023 13.6 0.6 0.023 13.6 0.4 1.5 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 DUF552 PF04472.7 AJW71122.1 - 0.047 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Herpes_UL46 PF03387.9 AJW71122.1 - 0.057 11.6 0.0 0.064 11.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL46 protein Iron_traffic PF04362.9 AJW71122.1 - 0.076 12.4 0.0 0.22 10.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking AMP-binding PF00501.23 AJW71123.1 - 1.6e-96 323.2 0.0 2.1e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AJW71123.1 - 5.8e-21 75.2 0.1 1.2e-20 74.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBFD_NFYB_HMF PF00808.18 AJW71124.1 - 0.0098 15.9 0.6 0.022 14.7 0.4 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Baculo_PEP_C PF04513.7 AJW71124.1 - 0.014 15.1 1.5 0.035 13.9 1.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC155 PF14662.1 AJW71124.1 - 0.21 11.1 9.7 0.96 9.0 6.7 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 FliT PF05400.8 AJW71124.1 - 0.47 10.8 6.2 1.5 9.2 3.9 2.1 2 0 0 2 2 2 0 Flagellar protein FliT Thy1 PF02511.10 AJW71126.1 - 1.1e-29 103.1 2.8 3.8e-16 59.0 1.0 2.5 2 0 0 2 2 2 2 Thymidylate synthase complementing protein SelR PF01641.13 AJW71127.1 - 1.9e-50 169.7 0.5 2.1e-50 169.5 0.4 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 AJW71127.1 - 0.016 15.2 3.1 0.073 13.1 2.2 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.8 AJW71127.1 - 0.047 13.3 0.6 3.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RIG-I_C-RD PF11648.3 AJW71127.1 - 0.063 13.1 0.6 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I DZR PF12773.2 AJW71127.1 - 0.17 11.7 4.4 4.5 7.1 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.14 AJW71127.1 - 0.17 11.6 2.6 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e HECT_2 PF09814.4 AJW71127.1 - 0.19 10.4 1.5 0.29 9.7 0.1 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-ribbon_3 PF13248.1 AJW71127.1 - 4.5 6.6 9.3 5.3 6.3 1.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain CodY PF06018.9 AJW71128.1 - 0.11 11.7 0.2 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 CodY GAF-like domain Homoserine_dh PF00742.14 AJW71129.1 - 8.7e-55 185.1 0.1 1.3e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 AJW71129.1 - 1.5e-05 25.3 0.0 3.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 AJW71129.1 - 1.7e-05 24.5 0.2 3.7e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PUA PF01472.15 AJW71130.1 - 1.8e-18 66.0 0.2 2.6e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 PUA domain Mut7-C PF01927.11 AJW71131.1 - 1.1e-41 142.2 0.2 1.2e-41 142.0 0.1 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain zf-DNA_Pol PF08996.5 AJW71131.1 - 0.021 14.2 0.4 0.026 13.8 0.3 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger FemAB PF02388.11 AJW71131.1 - 0.028 13.1 0.1 0.044 12.4 0.1 1.3 1 0 0 1 1 1 0 FemAB family Zn-ribbon_8 PF09723.5 AJW71131.1 - 0.066 13.1 0.2 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 AJW71131.1 - 0.068 12.9 1.8 0.16 11.8 1.2 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain UPF0278 PF08745.6 AJW71131.1 - 0.078 12.2 0.4 0.14 11.3 0.1 1.6 1 1 1 2 2 2 0 UPF0278 family SprT-like PF10263.4 AJW71131.1 - 0.098 12.3 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 SprT-like family Proteasome PF00227.21 AJW71132.1 - 8.7e-46 155.6 0.0 1.1e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DoxX PF07681.7 AJW71134.1 - 5.6e-15 55.5 6.4 5.6e-15 55.5 4.4 1.6 1 1 1 2 2 2 2 DoxX DoxD PF04173.8 AJW71134.1 - 2.3e-05 24.1 4.5 4.1e-05 23.3 3.1 1.4 1 1 0 1 1 1 1 TQO small subunit DoxD DoxX_2 PF13564.1 AJW71134.1 - 8.1e-05 22.5 6.6 0.00014 21.8 4.5 1.5 1 1 0 1 1 1 1 DoxX-like family Calici_PP_N PF08405.6 AJW71134.1 - 0.24 10.1 2.1 0.3 9.8 1.5 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal Peptidase_M20 PF01546.23 AJW71135.1 - 5.7e-30 104.2 0.0 7.5e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AJW71135.1 - 3e-14 52.7 0.0 5.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Tox-PL-2 PF15643.1 AJW71135.1 - 0.02 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 2 WG_beta_rep PF14903.1 AJW71135.1 - 0.06 13.6 0.1 0.87 9.9 0.0 2.5 2 0 0 2 2 2 0 WG containing repeat Carb_kinase PF01256.12 AJW71136.1 - 3.4e-47 160.7 0.2 3.9e-47 160.5 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 AJW71136.1 - 2.3e-09 36.7 0.0 3.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 AJW71136.1 - 6.9e-07 28.7 0.0 9.9e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase GCD14 PF08704.5 AJW71137.1 - 5.8e-34 117.6 0.0 1.2e-33 116.6 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 AJW71137.1 - 1.4e-10 41.0 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJW71137.1 - 7e-10 38.7 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AJW71137.1 - 1.4e-08 35.2 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AJW71137.1 - 1.1e-07 31.9 0.0 2e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 AJW71137.1 - 3.9e-07 30.8 0.0 1.3e-06 29.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AJW71137.1 - 2.5e-06 26.7 0.0 4.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AJW71137.1 - 6.8e-06 26.4 0.0 1.7e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AJW71137.1 - 8.5e-06 24.9 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 AJW71137.1 - 1.2e-05 25.6 0.0 3.9e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 AJW71137.1 - 3.7e-05 22.8 0.0 6.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 AJW71137.1 - 5.8e-05 22.5 0.0 0.00032 20.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Fibrillarin PF01269.12 AJW71137.1 - 0.00014 20.8 0.0 0.00024 20.0 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin PrmA PF06325.8 AJW71137.1 - 0.00024 20.3 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 AJW71137.1 - 0.0021 18.4 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AJW71137.1 - 0.0033 16.8 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 AJW71137.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 AJW71137.1 - 0.035 13.8 0.0 0.065 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.1 AJW71137.1 - 0.065 12.8 0.2 0.94 9.1 0.0 2.4 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_32 PF13679.1 AJW71137.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 AJW71137.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 AJW71137.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) zinc-ribbons_6 PF07191.7 AJW71138.1 - 0.014 15.1 0.2 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbons RRN7 PF11781.3 AJW71138.1 - 0.041 13.3 0.9 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HIT PF04438.11 AJW71138.1 - 0.072 12.7 1.5 0.95 9.1 0.1 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-RING_3 PF14369.1 AJW71138.1 - 0.099 12.6 0.5 6.7 6.7 0.0 2.3 2 0 0 2 2 2 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 AJW71138.1 - 0.11 12.2 0.8 0.24 11.2 0.5 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AJW71138.1 - 0.14 11.4 1.2 0.34 10.2 0.8 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.2 AJW71138.1 - 0.25 11.1 2.5 0.97 9.3 1.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 AJW71138.1 - 0.26 10.7 3.2 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_6 PF13912.1 AJW71138.1 - 0.74 9.8 4.8 3.1 7.8 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger HNH_5 PF14279.1 AJW71138.1 - 1.4 9.0 5.5 7.8 6.5 0.6 2.8 1 1 0 2 2 2 0 HNH endonuclease Laminin_EGF PF00053.19 AJW71140.1 - 0.013 15.4 0.8 0.014 15.3 0.5 1.1 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) PolC_DP2 PF03833.8 AJW71140.1 - 0.013 13.2 0.1 0.013 13.2 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1610 PF07754.6 AJW71140.1 - 0.049 13.7 5.7 0.082 13.0 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) T4_baseplate PF12322.3 AJW71140.1 - 0.13 11.4 0.8 0.13 11.4 0.6 1.0 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-HIT PF04438.11 AJW71140.1 - 0.21 11.2 1.8 0.31 10.7 1.3 1.3 1 0 0 1 1 1 0 HIT zinc finger Zn_Tnp_IS1595 PF12760.2 AJW71140.1 - 0.95 9.3 5.2 0.49 10.2 0.4 2.0 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 AJW71140.1 - 2.4 7.7 4.9 11 5.6 0.1 2.1 1 1 1 2 2 2 0 InsA N-terminal domain DUF1216 PF06746.6 AJW71141.1 - 0.00014 21.6 1.3 0.00033 20.4 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1216) DUF3025 PF11227.3 AJW71141.1 - 0.0021 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3025) DUF505 PF04458.7 AJW71141.1 - 0.03 12.4 7.0 0.66 8.0 1.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF505) HTH_12 PF08461.5 AJW71141.1 - 0.066 12.9 0.9 0.52 10.0 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Lip_prot_lig_C PF10437.4 AJW71141.1 - 0.32 10.7 5.2 16 5.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus TrmB PF01978.14 AJW71141.1 - 0.32 10.7 3.9 2.8 7.6 0.0 3.0 3 1 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB D5_N PF08706.6 AJW71141.1 - 0.94 9.5 4.4 33 4.5 3.1 2.8 1 1 0 1 1 1 0 D5 N terminal like Spore_IV_A PF09547.5 AJW71141.1 - 1.4 7.5 8.8 0.74 8.4 1.9 2.2 1 1 1 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) Duffy_binding PF05424.6 AJW71141.1 - 4.5 7.0 12.7 1.6 8.4 5.8 2.1 1 1 2 3 3 3 0 Duffy binding domain MCPsignal PF00015.16 AJW71142.1 - 6e-21 74.9 6.8 2e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_I PF06008.9 AJW71142.1 - 0.16 11.2 6.2 0.34 10.2 0.7 2.3 2 0 0 2 2 2 0 Laminin Domain I Pyridox_oxidase PF01243.15 AJW71143.1 - 4.5e-12 45.8 0.0 5.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AJW71143.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PAC2 PF09754.4 AJW71144.1 - 2.7e-24 86.2 0.0 3.3e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 PAC2 family HGD-D PF06050.8 AJW71144.1 - 0.0051 15.6 0.1 0.0084 14.9 0.1 1.2 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component CBS PF00571.23 AJW71145.1 - 0.006 16.3 0.8 0.29 10.9 0.0 3.6 5 0 0 5 5 5 1 CBS domain Malic_M PF03949.10 AJW71146.1 - 8.7e-57 192.5 2.7 1.2e-56 192.1 1.8 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AJW71146.1 - 1.1e-22 80.5 3.4 1.2e-19 70.5 0.2 3.0 2 1 1 3 3 3 2 Malic enzyme, N-terminal domain Shikimate_DH PF01488.15 AJW71146.1 - 3e-07 30.6 1.2 9.9e-07 28.9 0.8 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 AJW71146.1 - 5.2e-07 29.4 0.3 1e-06 28.5 0.1 1.6 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.16 AJW71146.1 - 7.7e-06 25.8 2.5 3.7e-05 23.6 0.5 2.5 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.9 AJW71146.1 - 0.00042 20.2 0.1 0.00087 19.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 AJW71146.1 - 0.00066 19.5 0.7 0.0024 17.7 0.5 2.1 1 1 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.16 AJW71146.1 - 0.0049 16.4 0.5 0.017 14.7 0.4 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 AJW71146.1 - 0.0064 15.5 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 AJW71146.1 - 0.014 14.5 1.9 0.026 13.6 0.2 2.2 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 AJW71146.1 - 0.016 15.1 0.2 0.059 13.3 0.1 2.1 1 1 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 AJW71146.1 - 0.018 14.5 0.1 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pribosyltran_N PF13793.1 AJW71146.1 - 0.02 14.6 0.2 0.067 12.9 0.1 1.9 1 1 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase THF_DHG_CYH_C PF02882.14 AJW71146.1 - 0.029 13.4 0.6 0.26 10.3 0.2 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RNA_bind_2 PF10133.4 AJW71146.1 - 0.25 11.4 3.8 5.1 7.1 0.1 3.4 3 0 0 3 3 3 0 Predicted RNA-binding protein tRNA-synt_1d PF00750.14 AJW71147.1 - 2.6e-36 125.1 3.7 1.8e-29 102.6 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 AJW71147.1 - 3e-29 101.4 1.5 7.9e-29 100.0 0.0 2.5 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AJW71147.1 - 3.5e-16 59.5 0.2 1.1e-15 57.9 0.1 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 AJW71147.1 - 0.00037 19.7 0.2 0.001 18.2 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AJW71147.1 - 0.0035 16.0 0.1 0.013 14.2 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (M) RTX_C PF08339.5 AJW71147.1 - 0.039 13.6 0.9 0.24 11.1 0.4 2.5 1 1 1 2 2 2 0 RTX C-terminal domain Amidase_6 PF12671.2 AJW71147.1 - 0.12 12.3 0.3 0.47 10.4 0.1 2.0 2 0 0 2 2 2 0 Putative amidase domain Hydrolase_3 PF08282.7 AJW71148.1 - 1.6e-30 106.5 5.6 1.2e-21 77.4 1.2 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AJW71148.1 - 3.7e-07 29.6 0.1 0.001 18.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 AJW71148.1 - 4.7e-07 30.1 1.8 3.9e-05 23.8 0.1 2.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AJW71148.1 - 6.4e-05 23.4 0.7 0.032 14.6 0.4 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 AJW71148.1 - 6.8e-05 21.8 0.1 0.034 13.0 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_6 PF13344.1 AJW71148.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 AJW71148.1 - 0.033 13.5 0.9 9.6 5.4 0.0 3.0 2 1 1 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) RRM_4 PF10598.4 AJW71148.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif of the spliceosomal PrP8 DUF1469 PF07332.6 AJW71149.1 - 2.2 8.0 0.0 2.2 8.0 0.0 3.2 5 1 0 5 5 5 0 Protein of unknown function (DUF1469) TGS PF02824.16 AJW71151.1 - 1.9e-20 72.4 0.0 4.7e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AJW71151.1 - 8.8e-20 70.8 0.3 2.5e-19 69.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AJW71151.1 - 1.6e-15 56.7 2.5 1.3e-13 50.5 0.0 2.4 1 1 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 AJW71151.1 - 6.3e-05 22.8 0.4 0.3 10.9 0.2 2.7 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.11 AJW71151.1 - 0.00039 19.5 0.0 0.00076 18.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 AJW71151.1 - 0.0052 17.2 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 AJW71151.1 - 0.0075 15.4 0.3 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 AJW71151.1 - 0.0078 15.6 3.1 0.14 11.5 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 AJW71151.1 - 0.009 15.2 1.9 0.083 12.1 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family ArgK PF03308.11 AJW71151.1 - 0.028 13.1 0.2 0.16 10.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Baculo_FP PF03258.9 AJW71151.1 - 0.045 12.8 4.5 2.1 7.3 0.1 2.6 2 1 0 2 2 2 0 Baculovirus FP protein SRPRB PF09439.5 AJW71151.1 - 0.053 12.7 0.1 0.053 12.7 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AJW71151.1 - 0.095 12.8 0.7 1.7 8.8 0.0 2.8 1 1 2 3 3 3 0 AAA domain AAA_28 PF13521.1 AJW71151.1 - 0.16 11.9 0.2 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Collagen PF01391.13 AJW71153.1 - 6.1e-61 201.8 227.9 4.1e-09 35.8 22.6 7.6 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) TPR_11 PF13414.1 AJW71154.1 - 1.9e-24 85.0 0.6 6.2e-13 48.1 0.0 2.6 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 AJW71154.1 - 2.8e-24 83.6 1.1 1.2e-06 27.8 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 AJW71154.1 - 1.9e-23 80.4 1.7 5.1e-06 25.9 0.0 5.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 AJW71154.1 - 4.1e-18 65.5 0.0 1.1e-06 29.1 0.0 3.0 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJW71154.1 - 2.4e-17 63.0 0.3 4.8e-06 26.8 0.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AJW71154.1 - 1.3e-15 56.2 0.1 2.1e-05 24.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJW71154.1 - 9.2e-13 47.9 0.1 7.3e-06 25.8 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJW71154.1 - 1.1e-11 44.2 0.3 0.017 15.7 0.0 5.0 4 1 2 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 AJW71154.1 - 7.1e-11 41.0 4.3 0.0086 15.7 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 AJW71154.1 - 1.8e-08 34.4 0.1 0.00042 20.4 0.1 2.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AJW71154.1 - 2.5e-08 33.6 0.0 0.00022 21.0 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJW71154.1 - 8.8e-05 22.3 0.0 0.51 10.2 0.0 3.8 1 1 2 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AJW71154.1 - 9e-05 22.6 0.2 29 5.4 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat HTH_27 PF13463.1 AJW71154.1 - 0.00019 21.7 0.5 0.00087 19.5 0.1 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain NARP1 PF12569.3 AJW71154.1 - 0.00036 19.4 1.7 0.036 12.8 0.0 2.4 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 AJW71154.1 - 0.00087 18.9 0.3 27 4.8 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 AJW71154.1 - 0.0042 16.9 0.0 9.7 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 AJW71154.1 - 0.0091 16.0 0.3 2.1 8.5 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat FAM180 PF15173.1 AJW71154.1 - 0.021 14.6 0.3 2.9 7.6 0.0 2.8 3 0 0 3 3 3 0 FAM180 family Rapsyn_N PF10579.4 AJW71154.1 - 0.052 13.3 0.0 3 7.7 0.0 2.8 1 1 1 2 2 2 0 Rapsyn N-terminal myristoylation and linker region MarR_2 PF12802.2 AJW71154.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 MarR family Rhodanese PF00581.15 AJW71155.1 - 1.4e-35 122.0 0.0 1.2e-16 61.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NIR_SIR PF01077.17 AJW71156.1 - 5.7e-41 139.5 0.0 2.1e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 AJW71156.1 - 1.7e-30 104.4 0.0 1.7e-15 56.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF2023 PF09633.5 AJW71156.1 - 0.1 12.5 0.1 2.6 8.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2023) Thi4 PF01946.12 AJW71157.1 - 9.2e-65 217.9 0.1 1.1e-64 217.6 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 AJW71157.1 - 3.1e-14 52.6 0.2 4.5e-07 29.0 0.0 3.0 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 AJW71157.1 - 4.7e-10 39.1 0.0 7.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AJW71157.1 - 3.9e-09 35.8 0.2 2e-05 23.6 0.0 2.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AJW71157.1 - 2.6e-08 33.7 0.0 5.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 AJW71157.1 - 2.8e-07 29.9 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AJW71157.1 - 3.5e-07 30.2 0.1 5.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AJW71157.1 - 5.6e-07 28.3 0.0 8.2e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 AJW71157.1 - 8.9e-06 24.8 0.1 7.5e-05 21.8 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 AJW71157.1 - 0.00011 21.1 0.1 0.00018 20.4 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 AJW71157.1 - 0.00012 22.1 0.1 0.00021 21.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AJW71157.1 - 0.0054 15.4 0.0 0.73 8.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 AJW71157.1 - 0.0056 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 AJW71157.1 - 0.011 16.0 0.1 0.039 14.3 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 AJW71157.1 - 0.015 13.6 0.0 0.023 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Amino_oxidase PF01593.19 AJW71157.1 - 0.023 13.7 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase TrkA_N PF02254.13 AJW71157.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 AJW71157.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 AJW71157.1 - 0.13 12.4 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Ldh_1_C PF02866.13 AJW71159.1 - 1.2e-24 87.0 0.9 1.6e-24 86.5 0.1 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AJW71159.1 - 2.8e-22 79.0 0.0 4.5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 AJW71159.1 - 3.4e-05 23.2 0.0 8.6e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Family 4 glycosyl hydrolase Shikimate_DH PF01488.15 AJW71159.1 - 0.0076 16.3 0.2 0.026 14.6 0.0 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 AJW71159.1 - 0.022 14.1 2.5 0.35 10.2 1.7 2.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Usp PF00582.21 AJW71160.1 - 3.2e-29 101.9 0.0 3.6e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family SRP54 PF00448.17 AJW71160.1 - 0.01 15.3 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Glu_synthase PF01645.12 AJW71160.1 - 0.026 13.4 0.4 0.032 13.1 0.2 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase GARS_N PF02844.10 AJW71160.1 - 0.063 13.7 1.0 0.47 10.9 0.6 2.1 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain VirE PF05272.6 AJW71160.1 - 0.073 12.5 0.3 0.089 12.2 0.2 1.1 1 0 0 1 1 1 0 Virulence-associated protein E ImmE5 PF11480.3 AJW71160.1 - 0.094 12.5 0.2 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Colicin-E5 Imm protein Ribosomal_S30AE PF02482.14 AJW71161.1 - 0.00014 22.1 0.2 0.00018 21.8 0.1 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein CBS PF00571.23 AJW71162.1 - 5.4e-48 160.5 10.0 2.3e-15 56.1 0.3 4.1 4 0 0 4 4 4 4 CBS domain Usp PF00582.21 AJW71163.1 - 1.2e-28 99.9 0.0 1.4e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family MreC PF04085.9 AJW71163.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 rod shape-determining protein MreC Usp PF00582.21 AJW71164.1 - 1.6e-27 96.4 0.0 1.9e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.23 AJW71165.1 - 1.4e-28 98.4 1.3 7.9e-14 51.1 0.1 2.1 2 0 0 2 2 2 2 CBS domain Pyr_redox_2 PF07992.9 AJW71166.1 - 5.2e-30 104.8 7.3 1.6e-28 100.0 5.1 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJW71166.1 - 6.3e-19 68.1 2.0 1.2e-17 64.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AJW71166.1 - 5.9e-16 59.1 0.3 2.3e-10 40.9 0.0 3.1 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJW71166.1 - 9.8e-08 31.2 6.2 0.0029 16.5 0.0 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.17 AJW71166.1 - 1e-06 27.9 6.5 0.0039 16.1 0.0 4.6 4 1 1 5 5 5 1 Glucose inhibited division protein A K_oxygenase PF13434.1 AJW71166.1 - 1.7e-06 27.1 0.1 0.0097 14.8 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 AJW71166.1 - 2e-06 27.0 0.5 0.0013 17.8 0.0 2.5 2 1 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 AJW71166.1 - 2.8e-06 26.4 4.5 0.00045 19.1 0.1 3.5 2 1 2 4 4 4 2 FAD binding domain FAD_binding_3 PF01494.14 AJW71166.1 - 5.6e-06 25.6 1.1 0.013 14.5 0.0 3.0 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 AJW71166.1 - 5.7e-05 23.0 0.1 0.012 15.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AJW71166.1 - 0.00018 20.1 4.0 0.024 13.1 0.1 3.9 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.1 AJW71166.1 - 0.00039 20.6 0.8 0.0026 17.9 0.3 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 AJW71166.1 - 0.00068 18.8 0.3 0.0052 15.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AJW71166.1 - 0.0017 18.1 2.7 1.3 8.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.10 AJW71166.1 - 0.014 13.6 0.9 0.12 10.5 0.1 2.4 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 AJW71166.1 - 0.017 14.0 1.5 9.9 4.9 0.0 3.4 3 1 1 4 4 4 0 Lycopene cyclase protein XdhC_C PF13478.1 AJW71166.1 - 0.13 12.5 0.1 0.37 11.1 0.0 1.9 2 1 0 2 2 2 0 XdhC Rossmann domain Trp_halogenase PF04820.9 AJW71166.1 - 0.17 10.5 1.2 2 6.9 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase EMP70 PF02990.11 AJW71167.1 - 0.045 12.2 0.2 0.041 12.3 0.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 STN1_2 PF09170.5 AJW71167.1 - 0.058 13.1 2.6 0.095 12.4 1.8 1.4 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Tox-REase-7 PF15649.1 AJW71167.1 - 0.068 13.3 3.3 0.069 13.2 0.2 2.3 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 7 PALP PF00291.20 AJW71168.1 - 7.4e-55 186.3 0.0 9.4e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TusA PF01206.12 AJW71169.1 - 5.5e-22 77.1 0.0 6.2e-22 76.9 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA PHP_C PF13263.1 AJW71170.1 - 8.7e-12 44.3 0.0 1.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 PHP-associated PHP PF02811.14 AJW71170.1 - 6.9e-07 29.2 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 PHP domain CNPase PF05881.7 AJW71170.1 - 0.0034 16.8 0.0 0.0081 15.5 0.0 1.6 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) F420_ligase PF01996.11 AJW71171.1 - 5.2e-65 218.6 0.3 5.9e-65 218.5 0.2 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Hydrolase PF00702.21 AJW71172.1 - 1.8e-08 35.0 0.1 1.5e-07 32.0 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AJW71172.1 - 4.3e-07 30.2 0.1 5.9e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AJW71172.1 - 1.7e-06 28.4 0.0 2.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AJW71172.1 - 7.1e-05 22.5 0.1 0.0022 17.6 0.1 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HGTP_anticodon PF03129.15 AJW71174.1 - 7.8e-22 77.0 0.6 2.8e-21 75.2 0.4 2.0 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 AJW71174.1 - 4.9e-21 74.4 2.6 9.1e-21 73.5 0.5 2.4 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 AJW71174.1 - 1.9e-17 63.3 0.1 4.5e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RPA_interact_M PF14767.1 AJW71174.1 - 5.4 7.8 11.0 1 10.1 1.6 2.7 3 0 0 3 3 3 0 Replication protein A interacting middle FGE-sulfatase PF03781.11 AJW71175.1 - 7.6e-51 172.9 3.4 1.7e-50 171.7 2.3 1.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 AJW71175.1 - 1.5e-11 44.7 0.0 4.3e-11 43.2 0.0 1.8 2 1 0 2 2 2 1 DinB superfamily DinB PF05163.7 AJW71175.1 - 0.064 12.9 0.5 0.21 11.2 0.1 1.9 1 1 1 2 2 2 0 DinB family Corona_6B_7B PF03262.8 AJW71175.1 - 0.9 8.7 4.1 0.19 10.9 0.4 1.7 2 0 0 2 2 2 0 Coronavirus 6B/7B protein ABC_tran PF00005.22 AJW71176.1 - 1.5e-32 112.7 0.0 2.2e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 AJW71176.1 - 2.4e-17 63.0 0.2 4.7e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 AJW71176.1 - 1.4e-08 35.0 1.9 3.9e-06 27.0 1.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 AJW71176.1 - 7.5e-07 28.5 2.5 0.011 14.8 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AJW71176.1 - 4.1e-05 23.7 0.4 0.0009 19.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AJW71176.1 - 4.1e-05 23.6 0.0 7.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 AJW71176.1 - 8.6e-05 22.1 0.1 0.015 14.7 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain SMC_N PF02463.14 AJW71176.1 - 0.00026 20.2 1.1 0.0018 17.5 0.7 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 AJW71176.1 - 0.00026 21.1 0.3 0.0057 16.8 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AJW71176.1 - 0.00041 19.5 0.0 0.0009 18.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AJW71176.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 AJW71176.1 - 0.0014 18.8 0.1 0.0031 17.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AJW71176.1 - 0.0017 17.4 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 AJW71176.1 - 0.0039 17.9 0.3 0.016 16.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 AJW71176.1 - 0.005 16.4 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 AJW71176.1 - 0.0061 15.9 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 AJW71176.1 - 0.0081 14.6 0.0 0.51 8.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AJW71176.1 - 0.0092 14.9 0.0 0.019 13.8 0.0 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 AJW71176.1 - 0.028 14.1 0.7 0.13 11.9 0.5 2.0 1 1 0 1 1 1 0 Archaeal ATPase Sigma54_activat PF00158.21 AJW71176.1 - 0.03 13.8 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 AJW71176.1 - 0.035 14.2 0.1 0.082 13.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 AJW71176.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF87 PF01935.12 AJW71176.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Gtr1_RagA PF04670.7 AJW71176.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 AJW71176.1 - 0.064 12.9 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AJW71176.1 - 0.065 13.0 0.0 0.34 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AJW71176.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_23 PF13476.1 AJW71176.1 - 0.085 13.1 0.9 0.19 12.0 0.6 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AJW71176.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 AJW71176.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain CN_hydrolase PF00795.17 AJW71179.1 - 1.2e-15 57.3 0.0 4.3e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_binding_5 PF07994.7 AJW71180.1 - 1.7e-41 142.6 0.0 1.1e-40 139.9 0.0 1.9 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 AJW71180.1 - 5.4e-30 103.5 0.1 3e-29 101.0 0.0 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase AMP-binding_C_2 PF14535.1 AJW71180.1 - 0.077 13.0 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DS PF01916.12 AJW71181.1 - 1.2e-72 244.5 0.3 1.5e-72 244.2 0.2 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PAC2 PF09754.4 AJW71182.1 - 1.1e-22 80.9 0.0 1.4e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 PAC2 family LysE PF01810.13 AJW71183.1 - 1.9e-29 102.3 15.4 2.2e-29 102.1 10.7 1.0 1 0 0 1 1 1 1 LysE type translocator GWT1 PF06423.7 AJW71183.1 - 2 8.4 7.3 21 5.1 5.1 2.2 1 1 0 1 1 1 0 GWT1 DUF1980 PF09323.5 AJW71183.1 - 5.5 6.6 7.6 0.39 10.4 0.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) Alba PF01918.16 AJW71185.1 - 2.3e-10 39.9 0.5 3e-10 39.5 0.3 1.2 1 0 0 1 1 1 1 Alba Trypan_PARP PF05887.6 AJW71185.1 - 3.3e-05 23.7 86.9 18 5.0 60.3 2.2 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Prosystemin PF07376.6 AJW71186.1 - 0.053 12.8 2.3 0.072 12.4 1.6 1.4 1 1 0 1 1 1 0 Prosystemin IMS PF00817.15 AJW71187.1 - 2.7e-41 140.8 0.4 2e-40 138.0 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 AJW71187.1 - 1.6e-16 60.4 0.8 3.3e-16 59.3 0.5 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AJW71187.1 - 2.2e-08 33.6 0.0 5.4e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif TfoX_C PF04994.8 AJW71187.1 - 0.0018 18.1 1.2 1.4 8.8 0.0 3.6 3 1 1 4 4 4 2 TfoX C-terminal domain Cdd1 PF11731.3 AJW71187.1 - 0.0034 17.2 0.2 0.019 14.8 0.0 2.3 2 2 0 2 2 2 1 Pathogenicity locus DNA_pol_lambd_f PF10391.4 AJW71187.1 - 0.0047 16.4 0.1 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 AJW71187.1 - 0.0093 16.1 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Exosortase_EpsH PF09721.5 AJW71188.1 - 1.2e-06 27.9 27.6 3.1e-06 26.6 19.1 1.6 1 1 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF998 PF06197.8 AJW71188.1 - 9.5 5.4 24.9 0.43 9.8 8.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF998) Thioredoxin_4 PF13462.1 AJW71190.1 - 1.1e-32 113.3 0.0 1.3e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AJW71190.1 - 3.7e-16 59.2 0.1 5.1e-14 52.2 0.1 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 AJW71190.1 - 1.1e-05 25.5 0.0 3e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AJW71190.1 - 0.057 13.5 0.0 0.83 9.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_5 PF13743.1 AJW71190.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Ephrin_lbd PF01404.14 AJW71190.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain DUF4184 PF13803.1 AJW71191.1 - 0.082 12.2 0.0 0.082 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) zf-C2H2 PF00096.21 AJW71193.1 - 0.0004 20.5 0.9 0.00081 19.5 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 AJW71193.1 - 0.021 15.0 1.0 0.021 15.0 0.7 1.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 AJW71193.1 - 0.038 14.3 0.7 0.086 13.2 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AJW71193.1 - 1 9.8 3.9 3.7 8.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DNA_Packaging_2 PF11123.3 AJW71194.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 DNA packaging protein NAD_binding_2 PF03446.10 AJW71195.1 - 2.5e-41 141.2 1.7 6.1e-41 139.9 0.5 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AJW71195.1 - 1.1e-20 73.9 0.2 1.8e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 AJW71195.1 - 4.8e-08 33.3 2.1 5.6e-08 33.0 0.5 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AJW71195.1 - 1.1e-07 31.2 0.4 2e-07 30.3 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AJW71195.1 - 1.5e-07 30.9 1.0 3.8e-07 29.6 0.2 2.0 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 AJW71195.1 - 2.9e-07 30.6 0.3 5.4e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 AJW71195.1 - 2.8e-06 26.8 0.1 5.5e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 AJW71195.1 - 9.9e-06 25.3 0.8 0.00012 21.8 0.5 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 AJW71195.1 - 0.0001 22.0 0.7 0.0001 22.0 0.5 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AJW71195.1 - 0.00066 19.0 2.5 0.015 14.6 0.1 2.6 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 AJW71195.1 - 0.00096 19.3 0.5 0.0034 17.6 0.2 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Rossmann-like PF10727.4 AJW71195.1 - 0.0013 18.4 0.3 0.012 15.2 0.2 2.1 1 1 0 2 2 2 1 Rossmann-like domain Saccharop_dh PF03435.13 AJW71195.1 - 0.0036 16.3 0.2 0.0051 15.8 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox_2 PF07992.9 AJW71195.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AJW71195.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_C PF03720.10 AJW71195.1 - 0.019 15.1 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.13 AJW71195.1 - 0.034 14.1 0.2 0.13 12.3 0.1 2.1 1 1 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 AJW71195.1 - 0.048 14.1 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.1 AJW71195.1 - 0.073 13.0 0.2 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding adh_short_C2 PF13561.1 AJW71196.1 - 1.2e-37 130.0 0.4 1.5e-37 129.6 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AJW71196.1 - 1.7e-32 112.6 0.1 2.2e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AJW71196.1 - 9.3e-09 35.1 0.2 1.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AJW71196.1 - 5.3e-08 33.0 0.1 7.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AJW71196.1 - 5.8e-07 29.1 0.1 9.6e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AJW71196.1 - 0.00072 19.9 1.0 0.0018 18.6 0.7 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 AJW71196.1 - 0.0012 17.8 2.6 0.0016 17.3 1.8 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 AJW71196.1 - 0.0016 18.0 0.3 0.003 17.2 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AJW71196.1 - 0.0047 15.6 0.4 0.0063 15.2 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 AJW71196.1 - 0.065 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.5 AJW71196.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF99 PF01949.11 AJW71197.1 - 4.1e-55 185.7 0.0 4.9e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 DUF3185 PF11381.3 AJW71198.1 - 0.023 14.4 0.4 0.027 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) DUF3797 PF12677.2 AJW71199.1 - 0.013 15.1 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) GFA PF04828.9 AJW71199.1 - 0.044 13.7 0.5 0.31 11.0 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 AJW71199.1 - 0.14 11.3 0.7 0.33 10.2 0.5 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-Mss51 PF13824.1 AJW71199.1 - 0.22 11.3 0.2 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 FAD_oxidored PF12831.2 AJW71200.1 - 1.2e-16 60.8 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 AJW71200.1 - 8.5e-15 54.5 0.5 2.2e-07 30.1 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AJW71200.1 - 2.2e-11 43.2 0.2 4.9e-08 32.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 AJW71200.1 - 6.2e-11 41.9 0.0 1.4e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 AJW71200.1 - 6.1e-10 38.3 0.0 0.00014 20.6 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 AJW71200.1 - 1e-08 34.1 0.4 5.7e-08 31.6 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 AJW71200.1 - 1.5e-07 30.7 1.6 9.4e-07 28.1 1.1 2.1 1 1 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 AJW71200.1 - 1.7e-07 31.3 2.2 3.5e-07 30.2 1.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AJW71200.1 - 2.1e-07 30.1 1.4 2.7e-07 29.7 0.5 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 AJW71200.1 - 5.3e-07 28.8 0.0 9.9e-07 27.9 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 AJW71200.1 - 2.2e-06 27.6 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AJW71200.1 - 4e-06 27.0 0.0 6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AJW71200.1 - 0.0018 18.6 1.1 0.026 14.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AJW71200.1 - 0.0092 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 AJW71200.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4363 PF14276.1 AJW71201.1 - 0.00016 21.3 0.8 0.26 10.9 0.0 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4363) A2M_N PF01835.14 AJW71201.1 - 0.0036 17.5 0.0 1.5 9.1 0.0 3.3 3 0 0 3 3 3 1 MG2 domain FlgD_ig PF13860.1 AJW71201.1 - 0.012 15.3 0.0 0.18 11.5 0.0 2.7 3 0 0 3 3 3 0 FlgD Ig-like domain Methyltransf_23 PF13489.1 AJW71202.1 - 9e-20 71.0 0.0 1.1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW71202.1 - 1.3e-19 70.3 0.5 1.6e-19 69.9 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJW71202.1 - 4e-19 68.9 0.0 9.2e-19 67.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW71202.1 - 3.3e-12 46.7 0.0 5.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW71202.1 - 6e-12 46.1 0.0 9.4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW71202.1 - 6e-11 42.6 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AJW71202.1 - 6.3e-10 38.2 0.0 9.6e-10 37.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 AJW71202.1 - 6.9e-09 35.1 1.7 1e-08 34.6 0.5 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 AJW71202.1 - 1.2e-08 34.5 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 AJW71202.1 - 5e-08 32.2 1.1 1.6e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 Putative methyltransferase DOT1 PF08123.8 AJW71202.1 - 5.1e-07 29.2 0.4 5.1e-06 25.9 0.3 2.1 1 1 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 AJW71202.1 - 7.9e-07 28.6 0.0 1.7e-06 27.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 AJW71202.1 - 5.8e-05 22.3 1.2 8.2e-05 21.8 0.8 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 AJW71202.1 - 9e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 AJW71202.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 AJW71202.1 - 0.00031 20.3 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 AJW71202.1 - 0.00038 19.6 0.1 0.00049 19.3 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 AJW71202.1 - 0.00051 19.7 0.0 0.00068 19.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AJW71202.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 AJW71202.1 - 0.002 17.2 0.1 0.0033 16.5 0.1 1.4 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_5 PF01795.14 AJW71202.1 - 0.023 13.9 0.0 0.16 11.1 0.0 2.0 1 1 1 2 2 2 0 MraW methylase family DREV PF05219.7 AJW71202.1 - 0.047 12.5 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_2 PF00891.13 AJW71202.1 - 0.047 12.8 0.1 0.12 11.5 0.0 1.8 2 1 0 2 2 2 0 O-methyltransferase DUF268 PF03269.9 AJW71202.1 - 0.057 13.0 2.1 0.092 12.3 1.0 1.8 1 1 1 2 2 2 0 Caenorhabditis protein of unknown function, DUF268 UPF0052 PF01933.13 AJW71205.1 - 2.4e-48 164.9 0.0 3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CofC PF01983.11 AJW71206.1 - 2.9e-21 75.4 5.3 3.7e-21 75.1 3.7 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.2 AJW71206.1 - 0.0028 17.7 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4284 PF14112.1 AJW71206.1 - 0.016 15.6 3.8 0.041 14.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4284) TFIIB PF00382.14 AJW71207.1 - 3.7e-37 125.9 5.3 5.4e-18 64.5 0.7 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW71207.1 - 2.2e-12 46.1 2.9 3.7e-12 45.3 2.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 AJW71207.1 - 0.00018 20.5 3.1 0.00038 19.5 2.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Sigma70_r4 PF04545.11 AJW71207.1 - 0.0002 20.6 0.0 0.082 12.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.18 AJW71207.1 - 0.0029 17.1 0.1 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AJW71207.1 - 0.0053 16.6 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain HTH_AsnC-type PF13404.1 AJW71207.1 - 0.0059 16.1 0.1 0.26 10.8 0.0 2.8 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain DZR PF12773.2 AJW71207.1 - 0.015 15.1 2.3 0.03 14.1 1.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.1 AJW71207.1 - 0.029 14.6 1.3 0.062 13.6 0.5 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar HTH_23 PF13384.1 AJW71207.1 - 0.052 13.2 0.3 0.41 10.3 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Ribosomal_S27 PF01599.14 AJW71207.1 - 0.058 13.2 2.1 0.13 12.1 1.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a HypA PF01155.14 AJW71207.1 - 0.14 11.8 0.6 2.7 7.7 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family LacI PF00356.16 AJW71207.1 - 0.22 11.1 1.4 1.6 8.4 0.1 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family zf-NADH-PPase PF09297.6 AJW71207.1 - 0.54 9.8 8.4 0.84 9.1 0.4 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 AJW71207.1 - 0.65 9.5 9.2 7.2 6.2 6.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 AJW71207.1 - 5.5 6.8 5.7 28 4.6 0.2 2.5 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Abi PF02517.11 AJW71208.1 - 1.1e-10 41.4 15.6 1.1e-10 41.4 10.8 2.5 2 1 0 2 2 2 1 CAAX protease self-immunity SUI1 PF01253.17 AJW71209.1 - 2.4e-21 75.3 0.2 2.9e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Auto_anti-p27 PF06677.7 AJW71210.1 - 1.7e-08 34.0 1.9 2.4e-08 33.5 1.3 1.2 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.1 AJW71210.1 - 0.16 11.5 1.9 9.6 5.8 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain DUF3160 PF11369.3 AJW71210.1 - 0.43 8.8 3.4 0.49 8.6 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Sec61_beta PF03911.11 AJW71211.1 - 1.4e-13 50.4 0.3 1.5e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family DUF2070 PF09843.4 AJW71212.1 - 7.7e-45 152.5 0.0 1.4e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) TraG-D_C PF12696.2 AJW71212.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG NB PF04159.8 AJW71212.1 - 0.068 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 NB glycoprotein Mrr_cat PF04471.7 AJW71213.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Hjc PF01870.13 AJW71213.1 - 0.011 15.2 0.1 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) NERD PF08378.6 AJW71213.1 - 0.028 14.6 0.1 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Nuclease-related domain SBP_bac_5 PF00496.17 AJW71214.1 - 2.9e-26 92.1 11.4 1.9e-22 79.6 0.0 3.2 3 1 0 3 3 3 2 Bacterial extracellular solute-binding proteins, family 5 Middle DUF367 PF04034.8 AJW71215.1 - 1.5e-35 121.5 0.0 1.9e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AJW71215.1 - 1.9e-07 30.5 0.2 2.8e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI WavE PF07507.6 AJW71215.1 - 0.078 11.8 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis A2M_N PF01835.14 AJW71216.1 - 3.8e-31 107.2 15.9 1.9e-07 31.2 0.0 9.5 8 3 0 8 8 8 6 MG2 domain LTD PF00932.14 AJW71216.1 - 7.9e-13 48.5 0.9 7.9e-13 48.5 0.6 3.5 4 0 0 4 4 4 1 Lamin Tail Domain Reeler PF02014.11 AJW71216.1 - 0.063 13.5 1.4 5 7.3 0.0 4.3 5 0 0 5 5 5 0 Reeler domain PG_binding_1 PF01471.13 AJW71221.1 - 0.07 13.1 0.0 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DnaJ PF00226.26 AJW71222.1 - 2.1e-16 59.4 0.5 5.6e-16 58.0 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain DUF4428 PF14471.1 AJW71222.1 - 2.8 7.7 8.4 4.8 7.0 1.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) 2_5_RNA_ligase2 PF13563.1 AJW71223.1 - 9.1e-16 57.9 0.0 1.6e-15 57.1 0.0 1.3 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.4 AJW71223.1 - 0.0002 21.1 0.3 0.00034 20.3 0.2 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain CAP PF00188.21 AJW71224.1 - 9.4e-17 61.6 3.4 9.4e-17 61.6 2.4 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family FUN14 PF04930.10 AJW71224.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 FUN14 family A2L_zn_ribbon PF08792.5 AJW71224.1 - 0.044 13.2 1.4 0.044 13.2 0.9 2.4 3 0 0 3 3 3 0 A2L zinc ribbon domain PP-binding PF00550.20 AJW71224.1 - 0.14 12.4 0.1 22 5.4 0.0 2.4 2 0 0 2 2 2 0 Phosphopantetheine attachment site Reprolysin_4 PF13583.1 AJW71225.1 - 1.1e-05 25.0 0.2 0.00016 21.2 0.0 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like TSP_3 PF02412.13 AJW71225.1 - 0.00012 21.4 9.2 0.0047 16.3 0.3 2.9 3 0 0 3 3 3 2 Thrombospondin type 3 repeat Peptidase_M10 PF00413.19 AJW71225.1 - 0.0004 20.1 1.0 0.013 15.2 0.0 3.2 2 1 0 2 2 2 1 Matrixin Reprolysin_2 PF13574.1 AJW71225.1 - 0.0026 17.8 0.1 0.03 14.3 0.0 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AJW71225.1 - 0.014 15.2 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 AATF-Che1 PF13339.1 AJW71225.1 - 0.028 14.5 2.4 0.029 14.5 0.4 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Rapamycin_bind PF08771.6 AJW71225.1 - 0.036 14.1 0.3 0.13 12.3 0.2 2.0 1 0 0 1 1 1 0 Rapamycin binding domain Reprolysin_3 PF13582.1 AJW71225.1 - 0.047 14.2 0.3 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 AJW71225.1 - 0.22 11.1 4.0 0.27 10.8 0.1 2.9 3 1 0 3 3 3 0 Pregnancy-associated plasma protein-A Ead_Ea22 PF13935.1 AJW71226.1 - 0.23 11.7 0.1 0.23 11.7 0.1 1.9 2 1 0 2 2 2 0 Ead/Ea22-like protein DUF3732 PF12532.3 AJW71228.1 - 2.1e-51 174.2 1.3 2.1e-51 174.2 0.9 2.9 2 1 0 3 3 3 1 Protein of unknown function (DUF3732) AAA_23 PF13476.1 AJW71228.1 - 5.5e-07 30.1 2.0 5.5e-07 30.1 1.4 3.7 2 1 2 4 4 4 1 AAA domain SMC_N PF02463.14 AJW71228.1 - 6.3e-06 25.5 2.4 2.5e-05 23.6 0.1 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AJW71228.1 - 0.00025 20.5 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 AJW71228.1 - 0.00043 19.5 0.5 0.0011 18.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 CENP-F_leu_zip PF10473.4 AJW71228.1 - 0.002 17.9 5.0 0.002 17.9 3.5 4.2 2 2 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_21 PF13304.1 AJW71228.1 - 0.011 15.7 0.5 0.011 15.7 0.4 3.7 1 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 AJW71228.1 - 0.047 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain GAS PF13851.1 AJW71228.1 - 0.065 12.4 24.6 0.016 14.4 3.3 3.4 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 AJW71228.1 - 0.15 11.9 4.5 0.95 9.3 0.3 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_16 PF13191.1 AJW71228.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.6 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 AJW71228.1 - 0.63 10.3 14.7 0.21 11.8 3.2 3.6 2 2 0 2 2 2 0 ABC transporter Baculo_PEP_C PF04513.7 AJW71228.1 - 1 9.2 6.7 0.66 9.8 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.4 AJW71228.1 - 7.6 6.7 10.1 19 5.5 1.7 3.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Myb_DNA-bind_2 PF08914.6 AJW71230.1 - 0.039 13.7 0.3 0.07 12.9 0.2 1.5 1 0 0 1 1 1 0 Rap1 Myb domain DUF2492 PF10678.4 AJW71230.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) IL22 PF14565.1 AJW71230.1 - 0.12 12.3 0.1 0.13 12.3 0.1 1.0 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Phage_integrase PF00589.17 AJW71232.1 - 6.5e-14 51.9 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family MMtag PF10159.4 AJW71232.1 - 5.5 7.1 6.7 0.94 9.5 0.5 2.8 3 1 0 3 3 3 0 Kinase phosphorylation protein DZR PF12773.2 AJW71233.1 - 0.0036 17.0 1.5 0.0041 16.8 1.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF1272 PF06906.6 AJW71233.1 - 0.014 15.2 2.0 0.019 14.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PolC_DP2 PF03833.8 AJW71233.1 - 0.03 12.0 0.2 0.03 12.0 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF910 PF06014.6 AJW71233.1 - 0.043 13.7 0.2 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) zf-C3HC4_3 PF13920.1 AJW71233.1 - 0.048 13.3 1.6 0.064 12.9 1.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 AJW71233.1 - 0.23 10.8 3.4 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 AJW71233.1 - 0.49 9.6 5.2 1.9 7.8 1.0 2.1 1 1 2 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJW71233.1 - 0.49 9.9 3.3 13 5.3 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 AJW71233.1 - 1.2 8.8 6.0 1 9.1 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Peptidase_S8 PF00082.17 AJW71235.1 - 1.7e-21 76.6 6.7 3.2e-18 65.8 0.5 4.1 3 1 0 3 3 3 2 Subtilase family HATPase_c PF02518.21 AJW71236.1 - 3.3e-22 78.3 0.0 5.9e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.20 AJW71236.1 - 6e-13 48.7 0.8 7e-12 45.3 0.0 3.0 3 0 0 3 3 3 1 HAMP domain 4HB_MCP_1 PF12729.2 AJW71236.1 - 6.9e-12 45.0 11.3 6.9e-12 45.0 7.8 2.4 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction HisKA PF00512.20 AJW71236.1 - 2e-09 37.2 2.8 5.4e-08 32.7 0.0 3.7 3 2 2 5 5 5 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW71236.1 - 2.3e-08 33.6 0.1 1.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 AJW71236.1 - 0.0018 17.9 0.2 0.0046 16.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW71236.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain TarH PF02203.10 AJW71236.1 - 0.045 13.5 2.9 0.12 12.1 2.0 1.8 1 1 0 1 1 1 0 Tar ligand binding domain homologue Response_reg PF00072.19 AJW71237.1 - 7.7e-22 77.4 0.5 2.3e-21 75.8 0.3 1.9 1 0 0 1 1 1 1 Response regulator receiver domain TrmB PF01978.14 AJW71237.1 - 5.4e-14 51.6 0.0 1.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB B12-binding PF02310.14 AJW71237.1 - 0.0075 16.1 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 2 B12 binding domain Regulator_TrmB PF11495.3 AJW71237.1 - 0.024 13.5 1.2 0.033 13.1 0.3 1.6 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Peptidase_M24 PF00557.19 AJW71239.1 - 9.9e-38 129.7 0.7 2.6e-37 128.4 0.5 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 Tn7_Tnp_TnsA_C PF08721.6 AJW71239.1 - 0.062 13.3 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 TnsA endonuclease C terminal CARD PF00619.16 AJW71239.1 - 0.072 12.9 0.1 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 Caspase recruitment domain FAR1 PF03101.10 AJW71240.1 - 0.032 14.7 1.6 0.035 14.6 1.1 1.1 1 0 0 1 1 1 0 FAR1 DNA-binding domain SIR2 PF02146.12 AJW71240.1 - 0.032 13.9 1.4 0.036 13.7 1.0 1.0 1 0 0 1 1 1 0 Sir2 family DUF2318 PF10080.4 AJW71240.1 - 0.16 11.7 2.0 0.19 11.5 1.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-TFIIB PF13453.1 AJW71240.1 - 0.39 9.9 4.1 1.8 7.8 2.9 1.9 1 1 0 1 1 1 0 Transcription factor zinc-finger zinc_ribbon_2 PF13240.1 AJW71240.1 - 0.41 10.1 3.9 3.5 7.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Nop10p PF04135.7 AJW71240.1 - 0.43 10.3 1.9 0.51 10.1 0.2 1.9 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family DnaJ_CXXCXGXG PF00684.14 AJW71240.1 - 0.44 10.6 5.5 0.63 10.1 3.8 1.3 1 1 0 1 1 1 0 DnaJ central domain OrfB_Zn_ribbon PF07282.6 AJW71240.1 - 0.8 9.4 6.7 1.2 8.8 4.6 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 AJW71240.1 - 0.99 9.4 5.5 1.8 8.6 3.8 1.5 1 1 0 1 1 1 0 Zinc ribbon domain TNFR_c6 PF00020.13 AJW71240.1 - 1.4 9.0 7.8 0.2 11.7 0.9 2.1 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region TFIIS_C PF01096.13 AJW71240.1 - 1.5 8.5 6.1 58 3.4 4.2 2.3 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 AJW71240.1 - 1.8 8.8 4.5 14 6.0 3.2 1.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF1512 PF07431.7 AJW71241.1 - 1.4e-102 343.0 4.4 1.7e-102 342.8 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) V-SNARE PF05008.10 AJW71241.1 - 0.052 13.7 3.6 18 5.6 0.1 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TBP PF00352.16 AJW71242.1 - 2.4e-61 203.0 0.0 3.9e-30 103.0 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AJW71242.1 - 4.3e-07 29.8 0.0 0.00036 20.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) BRCT PF00533.21 AJW71242.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain tRNA_bind PF01588.15 AJW71243.1 - 2.2e-22 78.7 0.0 2.4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain Helicase_C PF00271.26 AJW71245.1 - 0.092 12.6 0.0 0.092 12.6 0.0 1.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Polyketide_cyc2 PF10604.4 AJW71246.1 - 2.3e-11 44.0 0.0 2.5e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 AJW71246.1 - 1.4e-06 28.2 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.6 AJW71246.1 - 0.009 15.6 0.0 0.0098 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) AHSA1 PF08327.6 AJW71246.1 - 0.021 14.9 0.1 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.6 AJW71246.1 - 0.047 13.5 0.7 0.087 12.6 0.5 1.5 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal COXG PF06240.8 AJW71246.1 - 0.082 12.5 1.0 0.36 10.4 0.7 1.9 1 1 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Glycos_transf_2 PF00535.21 AJW71247.1 - 3.5e-30 104.9 0.0 4.9e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AJW71247.1 - 4.9e-18 65.7 0.0 6.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AJW71247.1 - 1.1e-09 37.7 0.0 2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AJW71247.1 - 6.8e-08 31.9 0.1 9e-08 31.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AJW71247.1 - 0.00022 21.4 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.9 AJW71247.1 - 0.074 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Anp1 Trypsin_2 PF13365.1 AJW71248.1 - 2.8e-21 75.7 0.3 5.6e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 AJW71248.1 - 2.4e-13 50.1 0.1 5.6e-13 48.9 0.1 1.6 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 AJW71248.1 - 4.8e-12 45.5 2.5 5.5e-12 45.4 0.6 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 AJW71248.1 - 0.009 16.1 4.1 1.8 8.8 0.1 3.5 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S29 PF02907.10 AJW71248.1 - 0.01 15.3 0.1 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.4 AJW71248.1 - 0.12 10.7 3.0 0.24 9.7 0.5 1.9 2 0 0 2 2 2 0 Peptidase S46 CBM_15 PF03426.9 AJW71248.1 - 0.14 11.5 1.8 3.5 6.9 0.1 2.5 1 1 1 2 2 2 0 Carbohydrate binding domain (family 15) DUF2178 PF09946.4 AJW71248.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.5 3 1 1 4 4 4 0 Predicted membrane protein (DUF2178) Radical_SAM PF04055.16 AJW71249.1 - 5.5e-13 49.4 0.0 9.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.8 AJW71249.1 - 0.03 14.1 0.1 0.093 12.5 0.1 1.8 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain DUF633 PF04816.7 AJW71249.1 - 0.12 11.7 1.0 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF633) Radical_SAM PF04055.16 AJW71250.1 - 3.6e-21 76.0 0.3 7.7e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily PmbA_TldD PF01523.11 AJW71251.1 - 4.7e-51 173.8 0.1 6.1e-51 173.4 0.1 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Na_Ca_ex PF01699.19 AJW71252.1 - 7.4e-44 148.7 37.3 1.2e-23 83.2 11.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3754 PF12576.3 AJW71252.1 - 1.7 8.2 5.7 0.21 11.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Zea_mays_MuDR PF05928.6 AJW71253.1 - 0.051 12.9 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Ammonium_transp PF00909.16 AJW71254.1 - 1.5e-114 382.6 33.9 1.7e-114 382.4 23.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family P-II PF00543.17 AJW71255.1 - 3.3e-12 46.7 0.4 4e-12 46.4 0.3 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Fst_toxin PF13955.1 AJW71256.1 - 5.8 6.7 6.4 8.7 6.1 4.4 1.3 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system P-II PF00543.17 AJW71258.1 - 4.2e-09 36.8 2.6 9.1e-09 35.7 1.8 1.6 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II HTH_45 PF14947.1 AJW71259.1 - 0.0071 16.1 0.2 0.0098 15.6 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 AJW71259.1 - 0.03 13.9 0.1 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) PAC2 PF09754.4 AJW71260.1 - 1.6e-39 136.0 0.0 2e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 PAC2 family AIRS_C PF02769.17 AJW71261.1 - 1.9e-22 79.9 0.0 3.5e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AJW71261.1 - 6.7e-17 61.5 1.1 1.4e-16 60.4 0.7 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain TRAM PF01938.15 AJW71262.1 - 0.034 13.9 0.1 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 TRAM domain Gram_pos_anchor PF00746.16 AJW71262.1 - 0.12 12.1 2.1 0.19 11.5 1.5 1.3 1 0 0 1 1 1 0 Gram positive anchor Na_H_Exchanger PF00999.16 AJW71263.1 - 2.3e-65 220.5 53.7 3e-65 220.2 37.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PspB PF06667.7 AJW71263.1 - 0.022 14.6 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B MFS_1_like PF12832.2 AJW71263.1 - 0.093 12.5 0.4 0.093 12.5 0.3 3.5 4 0 0 4 4 4 0 MFS_1 like family HC2 PF07382.6 AJW71264.1 - 1.6e-08 34.6 117.2 1.6e-08 34.6 81.2 2.3 2 1 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Radical_SAM PF04055.16 AJW71265.1 - 3.6e-20 72.7 0.0 9.2e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AJW71265.1 - 1.4e-06 28.2 0.1 4.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJW71265.1 - 0.012 15.7 0.1 0.086 13.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UCR_UQCRX_QCR9 PF05365.7 AJW71265.1 - 0.017 14.7 0.0 0.066 12.8 0.0 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like tRNA-synt_1f PF01921.13 AJW71266.1 - 6.5e-109 363.8 0.0 9.6e-109 363.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.6 AJW71266.1 - 0.0078 14.9 0.2 0.028 13.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) PolyA_pol_RNAbd PF12627.2 AJW71266.1 - 0.011 15.2 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A tRNA-synt_1e PF01406.14 AJW71266.1 - 0.027 13.5 0.1 0.11 11.6 0.0 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 AJW71266.1 - 0.068 11.1 0.0 0.11 10.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Thioredoxin_3 PF13192.1 AJW71266.1 - 0.15 11.8 0.3 0.61 9.9 0.2 2.0 1 0 0 1 1 1 0 Thioredoxin domain NfeD PF01957.13 AJW71267.1 - 0.12 12.5 0.3 0.14 12.2 0.2 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Gram_pos_anchor PF00746.16 AJW71267.1 - 0.75 9.6 5.1 8.7 6.2 0.1 2.2 2 0 0 2 2 2 0 Gram positive anchor DUF1049 PF06305.6 AJW71267.1 - 3.1 7.3 5.1 0.7 9.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) WEMBL PF05701.6 AJW71268.1 - 0.00027 19.5 48.8 0.015 13.8 2.8 2.8 2 1 1 3 3 3 3 Weak chloroplast movement under blue light Snapin_Pallidin PF14712.1 AJW71268.1 - 0.0022 18.2 8.8 0.0022 18.2 6.1 3.6 2 1 0 3 3 3 1 Snapin/Pallidin DUF904 PF06005.7 AJW71268.1 - 0.041 14.1 6.1 0.041 14.1 4.2 5.2 3 1 1 4 4 3 0 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 AJW71268.1 - 0.35 10.7 59.3 0.12 12.2 4.3 3.7 2 1 1 3 3 3 0 Tropomyosin like Prefoldin_3 PF13758.1 AJW71268.1 - 0.62 9.8 27.9 0.89 9.3 3.5 4.1 2 2 2 4 4 4 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 AJW71268.1 - 0.72 9.5 54.5 3.6 7.3 13.6 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 AJW71268.1 - 1.2 6.3 42.6 2.1 5.6 29.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin PF00261.15 AJW71268.1 - 1.3 8.1 57.4 0.82 8.7 11.6 3.1 1 1 2 3 3 3 0 Tropomyosin Mnd1 PF03962.10 AJW71268.1 - 1.5 8.4 48.0 0.27 10.8 10.6 3.2 2 1 1 3 3 3 0 Mnd1 family EzrA PF06160.7 AJW71268.1 - 1.6 6.8 43.9 0.49 8.5 11.2 2.9 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Laminin_II PF06009.7 AJW71268.1 - 1.6 8.5 31.0 3.9 7.2 1.2 3.5 2 1 1 3 3 3 0 Laminin Domain II TFR_dimer PF04253.10 AJW71268.1 - 3.5 7.2 7.5 1.1 8.7 0.8 3.1 2 2 1 3 3 3 0 Transferrin receptor-like dimerisation domain CENP-F_leu_zip PF10473.4 AJW71268.1 - 6.3 6.6 58.2 8.6 6.2 13.5 3.4 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 AJW71268.1 - 7 5.5 53.8 0.41 9.6 18.3 3.0 2 1 1 3 3 3 0 Autophagy protein Apg6 TMPIT PF07851.8 AJW71268.1 - 9.4 5.2 36.1 0.15 11.1 9.2 2.9 2 1 1 3 3 3 0 TMPIT-like protein Pyridox_oxidase PF01243.15 AJW71269.1 - 1.5e-15 57.0 0.0 1.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.7 AJW71269.1 - 0.028 14.0 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) NfeD PF01957.13 AJW71271.1 - 0.011 15.8 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF3990 PF13151.1 AJW71272.1 - 0.0028 17.0 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Metallothio_Euk PF12749.2 AJW71273.1 - 0.073 13.1 7.9 0.086 12.8 5.5 1.1 1 0 0 1 1 1 0 Eukaryotic metallothionein Peptidase_S28 PF05577.7 AJW71274.1 - 0.019 13.5 0.1 0.02 13.4 0.1 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ferritin PF00210.19 AJW71275.1 - 2.9e-36 124.3 2.8 3.4e-36 124.1 1.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 AJW71275.1 - 0.00013 22.2 2.2 0.00019 21.7 1.5 1.3 1 0 0 1 1 1 1 Rubrerythrin DUF2400 PF09674.5 AJW71275.1 - 0.028 14.1 0.3 0.036 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) adh_short PF00106.20 AJW71275.1 - 0.06 13.2 0.1 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Apc5 PF12862.2 AJW71275.1 - 0.1 12.4 0.8 0.18 11.6 0.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF1477 PF07346.6 AJW71275.1 - 0.1 12.6 0.2 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) Lipoprotein_10 PF03202.8 AJW71275.1 - 0.11 12.5 0.4 0.24 11.4 0.2 1.6 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region Pro_CA PF00484.14 AJW71277.1 - 0.0063 16.5 3.0 0.04 13.9 1.7 2.3 1 1 0 1 1 1 1 Carbonic anhydrase Adenine_glyco PF03352.8 AJW71278.1 - 1.4e-81 272.3 0.5 1.5e-81 272.1 0.4 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase YqzM PF14141.1 AJW71279.1 - 0.026 14.3 0.7 0.12 12.1 0.5 2.1 1 0 0 1 1 1 0 YqzM-like protein CBS PF00571.23 AJW71280.1 - 4.6e-28 96.7 0.1 2.7e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 CBS domain Ribosomal_L9_C PF03948.9 AJW71280.1 - 0.1 12.6 0.6 9.5 6.3 0.0 2.4 2 1 0 2 2 2 0 Ribosomal protein L9, C-terminal domain DUF2066 PF09839.4 AJW71280.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) DLH PF01738.13 AJW71281.1 - 2.2e-09 36.9 0.0 2.2e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.13 AJW71282.1 - 8.4e-32 110.2 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AJW71282.1 - 8.1e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 AJW71282.1 - 1.2e-06 27.5 0.0 1.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 AJW71282.1 - 4.2e-06 25.8 0.0 5.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 AJW71282.1 - 4.4e-05 23.4 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 AJW71282.1 - 0.0003 20.5 0.1 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal SHOCT PF09851.4 AJW71283.1 - 8.4e-05 21.8 3.1 8.4e-05 21.8 2.1 2.3 3 0 0 3 3 3 1 Short C-terminal domain RdgC PF04381.7 AJW71283.1 - 0.0096 14.9 1.0 0.014 14.3 0.7 1.2 1 0 0 1 1 1 1 Putative exonuclease, RdgC Lsr2 PF11774.3 AJW71283.1 - 0.029 14.3 2.1 0.048 13.5 1.4 1.3 1 0 0 1 1 1 0 Lsr2 Nif11 PF07862.6 AJW71283.1 - 0.063 13.2 0.2 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function ATP-synt_B PF00430.13 AJW71283.1 - 0.11 12.2 5.5 0.31 10.8 3.8 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) TA0956 PF11513.3 AJW71283.1 - 0.38 10.8 2.9 0.61 10.1 1.8 1.5 1 1 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 CDT1 PF08839.6 AJW71284.1 - 0.069 13.0 0.4 0.81 9.6 0.3 2.2 1 1 0 1 1 1 0 DNA replication factor CDT1 like Baculo_gp41 PF04700.7 AJW71284.1 - 0.082 12.3 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Structural glycoprotein p40/gp41 conserved region DUF3969 PF13108.1 AJW71284.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) CBS PF00571.23 AJW71285.1 - 3e-42 142.1 3.7 6.4e-12 45.0 0.1 4.2 4 0 0 4 4 4 4 CBS domain PduV-EutP PF10662.4 AJW71285.1 - 0.093 12.2 1.4 1.4 8.3 0.1 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CBS PF00571.23 AJW71286.1 - 3.6e-06 26.6 0.1 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CBS domain Aminotran_1_2 PF00155.16 AJW71287.1 - 1.7e-40 139.1 0.0 3.2e-40 138.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AJW71287.1 - 0.0021 17.2 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AJW71287.1 - 0.062 11.5 0.0 0.13 10.4 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AJW71287.1 - 0.13 11.0 0.0 0.92 8.1 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V HATPase_c PF02518.21 AJW71289.1 - 1e-18 67.0 0.0 2.6e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW71289.1 - 2.9e-08 33.5 0.0 5.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW71289.1 - 1.2e-05 24.9 0.0 1.2e-05 24.9 0.0 2.4 3 1 0 3 3 3 1 GHKL domain HATPase_c_3 PF13589.1 AJW71289.1 - 0.035 13.7 0.1 0.089 12.4 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DivIC PF04977.10 AJW71289.1 - 0.038 13.4 0.4 0.038 13.4 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Mer2 PF09074.5 AJW71289.1 - 0.82 9.5 17.9 1.1 9.2 5.2 2.3 1 1 1 2 2 2 0 Mer2 THOC7 PF05615.8 AJW71289.1 - 0.85 9.8 7.6 0.61 10.3 0.4 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4419 PF14388.1 AJW71289.1 - 3.1 6.9 6.7 0.37 9.9 1.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4419) Kinetocho_Slk19 PF12709.2 AJW71289.1 - 7.3 6.7 8.7 2.1 8.4 2.5 2.4 2 1 0 2 2 2 0 Central kinetochore-associated Response_reg PF00072.19 AJW71290.1 - 7.1e-19 67.8 0.3 7.9e-19 67.7 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TIR-like PF10137.4 AJW71290.1 - 0.067 12.8 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain FleQ PF06490.6 AJW71290.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.3 1 1 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c PF02518.21 AJW71291.1 - 5.8e-31 106.4 0.3 1.2e-30 105.5 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW71291.1 - 4.6e-16 58.5 0.1 2.1e-15 56.4 0.0 2.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF3068 PF11271.3 AJW71291.1 - 3e-14 52.7 1.3 2.8e-13 49.5 0.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3068) HATPase_c_3 PF13589.1 AJW71291.1 - 0.0031 17.1 0.1 0.0066 16.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW71291.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ABC_sub_bind PF04392.7 AJW71292.1 - 1.8e-44 151.8 10.9 2.1e-44 151.6 7.6 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein Adeno_PV PF03910.8 AJW71292.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus minor core protein PV HATPase_c PF02518.21 AJW71293.1 - 1.5e-22 79.4 0.0 3.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW71293.1 - 7.1e-11 41.9 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW71293.1 - 3.4e-06 26.6 0.0 1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.1 AJW71293.1 - 0.0001 22.0 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF3377 PF11857.3 AJW71293.1 - 0.0036 16.8 0.9 0.11 12.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3377) HATPase_c_3 PF13589.1 AJW71293.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ykof PF07615.6 AJW71293.1 - 0.04 14.0 0.2 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 YKOF-related Family Lipoprotein_17 PF04200.7 AJW71293.1 - 0.11 12.6 3.7 0.54 10.4 2.6 2.2 1 0 0 1 1 1 0 Lipoprotein associated domain GCC2_GCC3 PF07699.8 AJW71294.1 - 0.00091 18.7 0.6 0.001 18.6 0.4 1.2 1 0 0 1 1 1 1 GCC2 and GCC3 DnaJ_CXXCXGXG PF00684.14 AJW71294.1 - 0.021 14.8 4.2 0.064 13.3 2.9 1.7 1 1 0 1 1 1 0 DnaJ central domain PADR1 PF08063.7 AJW71294.1 - 0.46 9.9 3.0 0.33 10.3 0.3 1.8 1 1 1 2 2 2 0 PADR1 (NUC008) domain zf-RanBP PF00641.13 AJW71294.1 - 0.78 8.9 3.8 3 7.0 0.1 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others EVI2A PF05399.6 AJW71295.1 - 0.94 8.6 3.9 1.1 8.4 2.7 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) zf-C2H2_4 PF13894.1 AJW71296.1 - 2e-07 30.8 7.2 0.0017 18.5 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AJW71296.1 - 1.7e-06 28.0 8.8 0.00085 19.5 0.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zinc_ribbon_5 PF13719.1 AJW71296.1 - 0.00032 20.2 4.1 0.054 13.0 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2H2_6 PF13912.1 AJW71296.1 - 0.00054 19.7 2.2 0.00054 19.7 1.5 2.9 2 1 0 2 2 2 1 C2H2-type zinc finger DUF678 PF05077.7 AJW71296.1 - 0.0026 17.6 1.5 0.99 9.4 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF678) zf-trcl PF13451.1 AJW71296.1 - 0.0029 17.2 1.0 1.6 8.4 0.2 2.3 2 0 0 2 2 2 2 Probable zinc-binding domain RNA_POL_M_15KD PF02150.11 AJW71296.1 - 0.0036 16.9 2.1 0.17 11.5 0.2 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-C2H2_3 PF13878.1 AJW71296.1 - 0.004 16.6 7.1 0.25 10.9 2.6 2.4 2 1 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zinc_ribbon_4 PF13717.1 AJW71296.1 - 0.0041 16.7 6.3 0.21 11.2 0.4 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Prok-RING_1 PF14446.1 AJW71296.1 - 0.0053 16.4 5.7 0.23 11.2 1.0 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 zf-CSL PF05207.8 AJW71296.1 - 0.0066 15.9 3.5 0.77 9.3 0.3 2.1 1 1 1 2 2 2 2 CSL zinc finger ADK_lid PF05191.9 AJW71296.1 - 0.0084 15.7 2.1 0.58 9.8 0.4 2.3 2 0 0 2 2 2 1 Adenylate kinase, active site lid zf-H2C2_2 PF13465.1 AJW71296.1 - 0.013 15.7 13.6 0.46 10.8 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain FYVE PF01363.16 AJW71296.1 - 0.02 14.7 9.6 0.18 11.7 6.6 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-DNA_Pol PF08996.5 AJW71296.1 - 0.023 14.0 4.0 0.026 13.8 2.7 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger HypA PF01155.14 AJW71296.1 - 0.035 13.7 5.6 0.047 13.3 1.9 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 AJW71296.1 - 0.038 13.6 1.9 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.1 AJW71296.1 - 0.053 12.7 2.9 1.9 7.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 AJW71296.1 - 0.062 13.1 6.9 0.11 12.3 4.8 1.5 1 1 0 1 1 1 0 Double zinc ribbon IBD PF10416.4 AJW71296.1 - 0.066 13.0 0.9 0.071 12.9 0.6 1.1 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD zf-C2H2_2 PF12756.2 AJW71296.1 - 0.073 13.1 6.3 2.3 8.3 1.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DNA_RNApol_7kD PF03604.8 AJW71296.1 - 0.1 12.0 7.3 0.11 12.0 0.1 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit RRN7 PF11781.3 AJW71296.1 - 0.1 12.1 2.6 3.2 7.3 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 PhnA_Zn_Ribbon PF08274.7 AJW71296.1 - 0.13 12.0 1.2 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-Sec23_Sec24 PF04810.10 AJW71296.1 - 0.14 11.7 0.7 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger XPA_N PF01286.13 AJW71296.1 - 0.16 11.7 6.1 1.2 8.8 0.1 2.5 3 0 0 3 3 2 0 XPA protein N-terminal zinc_ribbon_2 PF13240.1 AJW71296.1 - 0.21 11.1 2.2 10 5.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.7 AJW71296.1 - 0.22 10.9 3.7 5.6 6.4 0.2 2.3 2 0 0 2 2 2 0 HypF finger Zn-ribbon_8 PF09723.5 AJW71296.1 - 0.23 11.4 8.2 1.5 8.8 4.0 2.3 1 1 1 2 2 2 0 Zinc ribbon domain GATA PF00320.22 AJW71296.1 - 0.24 10.7 4.8 1.7 8.0 0.1 2.7 2 1 0 2 2 2 0 GATA zinc finger C1_1 PF00130.17 AJW71296.1 - 0.25 11.0 5.8 0.84 9.4 4.0 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 AJW71296.1 - 0.32 10.7 6.7 4 7.1 4.7 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 AJW71296.1 - 0.34 11.2 2.5 3 8.1 1.7 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar GCC2_GCC3 PF07699.8 AJW71296.1 - 0.35 10.4 7.9 12 5.5 5.5 2.1 1 1 0 1 1 1 0 GCC2 and GCC3 TF_Zn_Ribbon PF08271.7 AJW71296.1 - 0.36 10.1 3.2 4.9 6.5 0.3 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding SprT-like PF10263.4 AJW71296.1 - 0.43 10.2 6.3 1.7 8.3 4.3 1.8 1 1 0 1 1 1 0 SprT-like family LEA_1 PF03760.10 AJW71296.1 - 0.58 10.3 5.6 0.83 9.8 3.9 1.5 1 1 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Ogr_Delta PF04606.7 AJW71296.1 - 0.71 9.5 7.0 2.7 7.7 1.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF983 PF06170.7 AJW71296.1 - 0.76 9.9 2.2 4.1 7.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) NinG PF05766.7 AJW71296.1 - 0.86 9.3 11.1 0.36 10.5 2.5 2.0 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein zf-CHY PF05495.7 AJW71296.1 - 0.92 9.7 8.4 4.3 7.5 5.9 1.8 1 1 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.1 AJW71296.1 - 1.1 9.0 17.6 8.4 6.1 5.3 2.8 1 1 1 2 2 2 0 zinc-finger of a C2HC-type Zn_ribbon_recom PF13408.1 AJW71296.1 - 1.2 9.4 8.3 8.1 6.7 5.8 2.0 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain COX5B PF01215.14 AJW71296.1 - 1.4 8.6 5.3 7 6.3 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Vb Fer4 PF00037.22 AJW71296.1 - 1.6 8.4 4.7 6.4 6.5 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4379 PF14311.1 AJW71296.1 - 1.7 8.5 7.9 6.2 6.7 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4379) zf-CCHC PF00098.18 AJW71296.1 - 1.8 8.6 8.9 3.3 7.8 0.2 2.6 3 0 0 3 3 2 0 Zinc knuckle ZZ PF00569.12 AJW71296.1 - 1.9 8.0 5.7 1.4 8.4 0.1 2.4 2 1 0 2 2 2 0 Zinc finger, ZZ type zf-CHCC PF10276.4 AJW71296.1 - 2 8.3 4.4 13 5.6 0.1 2.5 3 0 0 3 3 2 0 Zinc-finger domain zf-BED PF02892.10 AJW71296.1 - 2.2 8.1 14.5 1.2 8.9 1.5 2.4 1 1 1 2 2 2 0 BED zinc finger zf-CCHC_6 PF15288.1 AJW71296.1 - 3.7 7.2 14.9 0.47 10.1 1.9 2.7 2 1 1 3 3 3 0 Zinc knuckle DM PF00751.13 AJW71296.1 - 6.5 6.3 15.8 2.1 7.9 3.6 2.2 2 0 0 2 2 2 0 DM DNA binding domain RibD_C PF01872.12 AJW71297.1 - 1.8e-14 53.8 0.2 3.2e-12 46.4 0.1 2.1 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.14 AJW71297.1 - 2e-09 37.2 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase MMS19_C PF12460.3 AJW71299.1 - 0.0011 17.7 6.9 0.0013 17.5 4.8 1.0 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal TrbC_Ftype PF09673.5 AJW71299.1 - 0.036 13.6 0.5 4.5 6.9 0.1 2.5 1 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein TSA PF03249.8 AJW71299.1 - 0.041 12.4 1.3 0.049 12.1 0.9 1.1 1 0 0 1 1 1 0 Type specific antigen DUF445 PF04286.7 AJW71299.1 - 0.041 13.4 5.4 0.051 13.0 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YpjP PF14005.1 AJW71299.1 - 0.048 13.4 3.4 0.057 13.1 2.0 1.5 1 1 0 1 1 1 0 YpjP-like protein HDAC4_Gln PF12203.3 AJW71299.1 - 0.079 12.9 3.6 0.14 12.0 2.5 1.4 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 Inhibitor_I34 PF10466.4 AJW71299.1 - 0.26 11.3 5.3 6.8 6.8 1.4 3.0 2 1 0 2 2 2 0 Saccharopepsin inhibitor I34 BLOC1_2 PF10046.4 AJW71299.1 - 0.4 10.8 12.3 0.22 11.6 1.5 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad3 PF08656.5 AJW71299.1 - 1.2 8.8 6.4 3.6 7.3 0.4 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad3 Noelin-1 PF12308.3 AJW71299.1 - 3.6 7.4 6.1 8.3 6.2 1.1 2.3 1 1 2 3 3 3 0 Neurogenesis glycoprotein Sec20 PF03908.8 AJW71299.1 - 5 6.9 10.1 0.51 10.0 1.4 2.2 2 0 0 2 2 2 0 Sec20 CENP-H PF05837.7 AJW71299.1 - 9 6.5 10.5 6.9 6.9 5.2 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) MIP PF00230.15 AJW71300.1 - 1.7e-53 181.4 19.1 2e-53 181.1 13.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ldr_toxin PF13940.1 AJW71300.1 - 0.0033 17.1 1.4 0.0033 17.1 1.0 2.1 2 0 0 2 2 2 1 Toxin Ldr, type I toxin-antitoxin system AhpC-TSA PF00578.16 AJW71301.1 - 1.3e-42 144.3 0.2 1.5e-42 144.1 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJW71301.1 - 1e-26 93.2 0.1 1.1e-26 93.1 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 AJW71301.1 - 2.1e-07 30.8 0.0 4.3e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 AJW71301.1 - 2.3e-06 27.2 0.0 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.9 AJW71301.1 - 0.00041 20.0 0.8 0.0016 18.0 0.5 1.8 1 1 0 1 1 1 1 SCO1/SenC GSHPx PF00255.14 AJW71301.1 - 0.033 13.5 0.0 0.082 12.2 0.0 1.7 1 1 1 2 2 2 0 Glutathione peroxidase UbiD PF01977.11 AJW71303.1 - 1e-156 521.4 0.0 1.2e-156 521.2 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF501 PF04417.7 AJW71303.1 - 0.13 12.0 0.4 0.72 9.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF501) DNA_methylase PF00145.12 AJW71303.1 - 0.14 11.2 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Radical_SAM PF04055.16 AJW71304.1 - 3.7e-16 59.7 0.0 6.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DeoC PF01791.4 AJW71305.1 - 1.4e-46 158.7 0.0 1.7e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHQS PF01959.11 AJW71306.1 - 1.3e-114 382.6 0.4 1.5e-114 382.4 0.3 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase (EC 4.6.1.3) GxDLY PF14607.1 AJW71306.1 - 0.12 11.8 0.0 0.4 10.1 0.0 1.9 2 1 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type DHquinase_I PF01487.10 AJW71307.1 - 6.9e-56 189.4 0.1 7.7e-56 189.2 0.1 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase Ribosomal_S24e PF01282.14 AJW71307.1 - 0.024 14.4 0.1 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S24e CTP_transf_2 PF01467.21 AJW71307.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Shikimate_dh_N PF08501.6 AJW71308.1 - 3.5e-27 94.2 0.0 9.5e-27 92.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AJW71308.1 - 7.5e-17 61.6 1.4 1.2e-16 61.0 1.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AJW71308.1 - 3.2e-05 23.0 0.2 3.9e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 AJW71308.1 - 0.0013 18.9 0.2 0.0022 18.2 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.12 AJW71308.1 - 0.0054 17.1 0.5 0.009 16.4 0.4 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GARS_N PF02844.10 AJW71308.1 - 0.034 14.6 0.3 0.077 13.4 0.2 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain WD40_alt PF14077.1 AJW71308.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif GHMP_kinases_N PF00288.21 AJW71309.1 - 4.8e-11 42.5 0.4 1.1e-10 41.3 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJW71309.1 - 6.3e-05 23.0 0.0 0.00043 20.4 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal RNase_PH PF01138.16 AJW71309.1 - 0.095 13.0 1.1 0.67 10.2 0.6 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 EPSP_synthase PF00275.15 AJW71310.1 - 1.8e-98 329.7 0.0 2.2e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HATPase_c PF02518.21 AJW71311.1 - 3.2e-20 71.8 0.1 3.6e-20 71.7 0.1 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 AJW71311.1 - 1.6e-08 34.1 0.0 1.8e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AJW71311.1 - 2.6e-06 27.1 0.1 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW71311.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_9 PF13426.1 AJW71312.1 - 1.2e-17 64.1 0.0 3.5e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 AJW71312.1 - 4.8e-10 39.2 0.2 1.4e-09 37.7 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 AJW71312.1 - 7.4e-10 38.6 0.0 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 AJW71312.1 - 8.2e-06 25.8 0.3 3.4e-05 23.8 0.2 2.1 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.5 AJW71312.1 - 1.5e-05 25.0 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 AJW71312.1 - 0.00079 19.2 0.0 0.0024 17.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain Bacillus_HBL PF05791.6 AJW71312.1 - 0.0014 18.0 6.7 0.0044 16.3 0.1 3.0 2 2 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) HAMP PF00672.20 AJW71312.1 - 0.0053 16.9 0.9 0.029 14.5 0.0 2.6 2 1 1 3 3 3 1 HAMP domain 4HB_MCP_1 PF12729.2 AJW71312.1 - 0.01 15.2 0.5 0.01 15.2 0.3 3.5 2 1 1 4 4 4 0 Four helix bundle sensory module for signal transduction ODV-E18 PF10717.4 AJW71312.1 - 0.023 14.0 3.9 0.068 12.6 2.7 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Syntaxin PF00804.20 AJW71312.1 - 0.034 14.3 0.8 0.034 14.3 0.6 2.6 2 0 0 2 2 2 0 Syntaxin GrpE PF01025.14 AJW71312.1 - 0.054 13.0 3.6 0.9 9.0 0.1 2.5 2 0 0 2 2 2 0 GrpE PhaP_Bmeg PF09602.5 AJW71312.1 - 0.29 10.9 5.6 1.9 8.2 0.6 2.3 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Syntaxin-6_N PF09177.6 AJW71312.1 - 3.2 8.2 7.9 1.9 8.9 0.5 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Chorismate_synt PF01264.16 AJW71313.1 - 2.4e-139 463.6 0.3 2.8e-139 463.4 0.2 1.0 1 0 0 1 1 1 1 Chorismate synthase EAF PF09816.4 AJW71313.1 - 0.14 12.1 0.0 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription elongation factor Aminotran_1_2 PF00155.16 AJW71314.1 - 4.4e-57 193.6 0.0 5.8e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.16 AJW71314.1 - 5.6e-12 45.5 0.4 1.3e-11 44.3 0.3 1.7 1 0 0 1 1 1 1 Chorismate mutase type II Aminotran_5 PF00266.14 AJW71314.1 - 6e-06 25.2 0.0 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AJW71314.1 - 3.3e-05 22.3 0.1 5.1e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AJW71314.1 - 0.00012 21.3 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AJW71314.1 - 0.00053 19.2 0.0 0.00082 18.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF1396 PF07161.8 AJW71314.1 - 0.0052 16.4 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1396) PDH PF02153.12 AJW71315.1 - 1.7e-24 86.1 0.3 2e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 AJW71315.1 - 8.2e-06 25.7 0.6 3.2e-05 23.8 0.0 2.1 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AJW71315.1 - 1.1e-05 24.6 0.0 2.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AJW71315.1 - 0.00022 20.9 0.3 0.00076 19.1 0.0 2.1 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AJW71315.1 - 0.0015 18.2 1.0 1.2 8.8 0.0 3.1 2 1 1 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 AJW71315.1 - 0.0018 18.6 0.4 0.011 16.0 0.0 2.6 3 1 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent Phage-tail_1 PF09097.5 AJW71315.1 - 0.012 15.1 0.8 0.027 14.0 0.4 1.5 1 1 0 1 1 1 0 Baseplate structural protein, domain 1 DapB_N PF01113.15 AJW71315.1 - 0.013 15.4 0.1 0.059 13.2 0.0 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 AJW71315.1 - 0.015 15.1 0.1 1.5 8.6 0.0 2.8 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain YqhG PF11079.3 AJW71315.1 - 0.024 13.4 0.8 0.038 12.8 0.2 1.5 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function Semialdhyde_dh PF01118.19 AJW71315.1 - 0.053 13.8 0.0 0.7 10.2 0.0 2.6 2 2 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.7 AJW71315.1 - 0.059 12.7 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 AJW71315.1 - 0.069 12.9 0.3 12 5.7 0.0 2.8 2 1 1 3 3 3 0 ThiF family NAD_binding_10 PF13460.1 AJW71315.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding NUDIX PF00293.23 AJW71316.1 - 1.6e-11 44.0 0.0 1.8e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 AJW71316.1 - 4.9e-05 22.7 0.1 0.00014 21.2 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain ThiC PF01964.13 AJW71317.1 - 5.7e-176 585.1 0.9 6.7e-176 584.9 0.6 1.0 1 0 0 1 1 1 1 ThiC family DUF2205 PF10224.4 AJW71318.1 - 0.0033 16.9 4.4 0.73 9.4 0.2 3.0 1 1 2 3 3 3 1 Predicted coiled-coil protein (DUF2205) HALZ PF02183.13 AJW71318.1 - 0.01 15.5 2.6 0.044 13.4 0.1 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3450 PF11932.3 AJW71318.1 - 0.037 13.2 0.5 0.04 13.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 AJW71318.1 - 0.068 12.7 3.1 0.078 12.5 2.2 1.2 1 0 0 1 1 1 0 IncA protein KLRAQ PF10205.4 AJW71318.1 - 0.072 13.1 1.0 0.073 13.1 0.5 1.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Phlebovirus_NSM PF07246.6 AJW71318.1 - 0.15 11.2 2.5 0.16 11.0 1.8 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FlxA PF14282.1 AJW71318.1 - 0.23 11.4 4.5 0.31 11.0 3.1 1.5 1 1 0 1 1 1 0 FlxA-like protein Shugoshin_N PF07558.6 AJW71318.1 - 0.31 10.7 0.3 0.31 10.7 0.2 2.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 AJW71318.1 - 0.33 10.7 0.2 0.33 10.7 0.1 2.5 2 1 1 3 3 3 0 Basic region leucine zipper DivIC PF04977.10 AJW71318.1 - 0.36 10.3 4.8 0.26 10.7 1.3 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF2681 PF10883.3 AJW71318.1 - 0.45 10.7 2.1 0.39 10.9 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) FlaC_arch PF05377.6 AJW71318.1 - 0.51 10.2 5.7 4.1 7.3 2.0 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 AJW71318.1 - 0.53 10.2 5.0 0.33 10.9 1.1 2.3 2 1 0 2 2 2 0 bZIP transcription factor IFP_35_N PF07334.8 AJW71318.1 - 1.1 9.2 4.4 0.44 10.5 0.9 1.8 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Phos_pyr_kin PF08543.7 AJW71319.1 - 1.6e-71 240.3 4.1 1.6e-71 240.3 2.8 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Aldolase_2 PF10120.4 AJW71319.1 - 9.8e-57 191.0 0.4 1.7e-56 190.2 0.2 1.4 1 0 0 1 1 1 1 Putative aldolase PfkB PF00294.19 AJW71319.1 - 1.9e-12 46.9 0.0 2.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 AJW71319.1 - 6.1e-05 22.4 0.3 0.00013 21.3 0.2 1.6 1 1 0 1 1 1 1 Carbohydrate kinase Bac_small_YrzI PF09501.5 AJW71319.1 - 0.23 11.3 3.5 0.17 11.7 0.5 2.3 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) NTP_transferase PF00483.18 AJW71320.1 - 2.8e-37 128.3 0.0 3.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AJW71320.1 - 5.6e-10 39.5 0.0 6.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AJW71320.1 - 0.027 14.0 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TPP_enzyme_C PF02775.16 AJW71320.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CTP_transf_3 PF02348.14 AJW71320.1 - 0.096 12.2 0.0 0.32 10.5 0.0 1.8 1 1 0 1 1 1 0 Cytidylyltransferase Acetyltransf_1 PF00583.19 AJW71321.1 - 6e-16 58.2 0.0 7.9e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJW71321.1 - 6.1e-16 58.3 0.0 8.3e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AJW71321.1 - 1.8e-08 34.5 0.0 2.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AJW71321.1 - 4.8e-08 32.9 0.0 5.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AJW71321.1 - 0.00028 20.8 0.1 0.00036 20.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AJW71321.1 - 0.035 13.8 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein MFS_1 PF07690.11 AJW71322.1 - 0.014 14.1 3.5 0.028 13.1 2.4 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily NfeD PF01957.13 AJW71322.1 - 0.025 14.6 0.9 0.047 13.8 0.2 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2162 PF09930.4 AJW71322.1 - 0.037 13.1 0.2 0.037 13.1 0.1 1.4 2 0 0 2 2 2 0 Predicted transporter (DUF2162) DUF4064 PF13273.1 AJW71322.1 - 0.043 13.9 7.1 0.71 10.0 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF1980 PF09323.5 AJW71322.1 - 0.17 11.6 6.0 1.2 8.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) DUF3784 PF12650.2 AJW71322.1 - 0.58 10.1 4.8 0.59 10.1 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) Tetraspannin PF00335.15 AJW71322.1 - 0.66 9.2 4.2 12 5.0 0.0 2.6 2 1 0 2 2 2 0 Tetraspanin family OppC_N PF12911.2 AJW71322.1 - 0.85 9.0 0.0 0.85 9.0 0.0 2.6 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF975 PF06161.6 AJW71322.1 - 7.8 6.1 9.3 1 9.0 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF975) GalP_UDP_transf PF01087.17 AJW71323.1 - 2e-10 41.0 0.0 7.6e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 AJW71323.1 - 2.2e-05 24.9 0.0 0.00045 20.6 0.0 2.3 2 0 0 2 2 2 1 HIT domain GalP_UDP_tr_C PF02744.12 AJW71323.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain PhosphMutase PF10143.4 AJW71324.1 - 5.3e-47 159.6 0.0 9.2e-47 158.8 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 AJW71324.1 - 1.5e-29 103.1 0.7 2.3e-29 102.5 0.5 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 AJW71324.1 - 0.0037 16.6 0.0 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Peptidase_S8 PF00082.17 AJW71324.1 - 0.063 12.4 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Subtilase family DUF309 PF03745.9 AJW71325.1 - 1.9e-18 65.6 0.5 3e-18 65.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) Ribosomal_S24e PF01282.14 AJW71326.1 - 0.00036 20.2 0.3 0.00072 19.2 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S27 PF01599.14 AJW71327.1 - 7e-21 73.7 5.3 8.7e-21 73.4 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a GCC2_GCC3 PF07699.8 AJW71327.1 - 0.00037 20.0 0.6 0.00048 19.6 0.4 1.2 1 0 0 1 1 1 1 GCC2 and GCC3 Ribosomal_L37e PF01907.14 AJW71327.1 - 0.0012 18.5 2.2 0.0019 17.9 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e G5 PF07501.7 AJW71327.1 - 0.0015 18.4 0.2 0.0018 18.1 0.2 1.1 1 0 0 1 1 1 1 G5 domain GFA PF04828.9 AJW71327.1 - 0.0039 17.0 2.3 0.032 14.1 0.1 2.0 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 AJW71327.1 - 0.0074 16.0 0.6 0.01 15.6 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 AJW71327.1 - 0.0082 15.5 1.0 0.015 14.7 0.7 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 AJW71327.1 - 0.014 15.0 2.1 0.019 14.6 1.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 AJW71327.1 - 0.038 13.4 1.4 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1451 PF07295.6 AJW71327.1 - 0.042 13.6 0.6 0.042 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) NCD3G PF07562.9 AJW71327.1 - 0.052 13.2 0.6 0.074 12.7 0.4 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR zf-ribbon_3 PF13248.1 AJW71327.1 - 0.076 12.2 3.4 0.21 10.8 2.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF1936 PF09151.5 AJW71327.1 - 0.076 12.5 3.2 4 7.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Nudix_N_2 PF14803.1 AJW71327.1 - 0.079 12.6 7.0 0.79 9.4 4.2 2.3 1 1 1 2 2 2 0 Nudix N-terminal SprT-like PF10263.4 AJW71327.1 - 0.082 12.5 0.7 0.085 12.5 0.5 1.0 1 0 0 1 1 1 0 SprT-like family HypA PF01155.14 AJW71327.1 - 0.091 12.4 0.8 0.1 12.3 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-NADH-PPase PF09297.6 AJW71327.1 - 0.21 11.1 2.6 2.4 7.7 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DNA_RNApol_7kD PF03604.8 AJW71327.1 - 0.53 9.7 4.4 1.2 8.6 3.0 1.6 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DUF2082 PF09855.4 AJW71327.1 - 0.76 9.6 3.5 5.8 6.8 0.1 2.1 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C2H2_3 PF13878.1 AJW71327.1 - 0.87 9.2 4.4 3.9 7.1 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_6 PF13912.1 AJW71327.1 - 3.5 7.6 7.5 6 6.9 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PhoU_div PF01865.11 AJW71328.1 - 0.0021 17.2 0.8 0.12 11.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF47 DUF4046 PF13255.1 AJW71328.1 - 0.037 12.7 0.3 0.048 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) Ada3 PF10198.4 AJW71329.1 - 0.062 13.0 0.4 0.068 12.9 0.3 1.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF4415 PF14384.1 AJW71329.1 - 0.062 13.4 0.4 0.069 13.3 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4415) Tox-ART-HYE1 PF15634.1 AJW71329.1 - 0.063 12.2 0.1 0.063 12.2 0.1 1.0 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase HMA PF00403.21 AJW71329.1 - 0.11 12.7 1.0 0.15 12.2 0.7 1.4 1 1 0 1 1 1 0 Heavy-metal-associated domain HTH_45 PF14947.1 AJW71330.1 - 3.6e-13 49.1 3.6 5.8e-13 48.4 2.5 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.1 AJW71330.1 - 0.031 14.6 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HSP33 PF01430.14 AJW71330.1 - 0.045 12.8 0.3 0.051 12.7 0.2 1.1 1 0 0 1 1 1 0 Hsp33 protein HemN_C PF06969.11 AJW71330.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 HemN C-terminal domain Rrf2 PF02082.15 AJW71330.1 - 0.12 12.5 0.1 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator MEDS PF14417.1 AJW71331.1 - 7.9e-12 44.6 0.3 9.8e-12 44.3 0.2 1.1 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HAD PF12710.2 AJW71331.1 - 0.035 14.2 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase KaiC PF06745.8 AJW71331.1 - 0.044 12.8 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 KaiC THUMP PF02926.12 AJW71332.1 - 0.00095 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 THUMP domain DUF2703 PF10865.3 AJW71332.1 - 0.092 12.6 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) zf-FCS PF06467.9 AJW71332.1 - 0.12 12.0 5.7 0.5 10.0 0.2 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif SRP54 PF00448.17 AJW71333.1 - 3.3e-69 232.2 0.1 6.4e-69 231.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AJW71333.1 - 1.5e-29 102.3 5.1 3.5e-29 101.1 1.2 2.8 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 AJW71333.1 - 2.4e-15 56.3 1.5 2.4e-15 56.3 1.0 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 AJW71333.1 - 1.4e-09 37.6 0.6 6.6e-09 35.4 0.4 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AJW71333.1 - 2.1e-05 24.4 0.1 0.0026 17.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 AJW71333.1 - 2.6e-05 25.0 0.6 0.00019 22.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 AJW71333.1 - 2.9e-05 23.5 1.5 8.6e-05 22.0 0.4 2.2 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 AJW71333.1 - 3.3e-05 23.6 0.4 7.9e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 AJW71333.1 - 8.4e-05 21.4 0.1 0.0017 17.1 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 AJW71333.1 - 0.00026 21.1 0.2 0.001 19.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 AJW71333.1 - 0.00032 20.3 0.5 0.001 18.7 0.0 2.1 3 0 0 3 3 1 1 Adenylylsulphate kinase KTI12 PF08433.5 AJW71333.1 - 0.00037 19.7 0.0 0.00087 18.5 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 PduV-EutP PF10662.4 AJW71333.1 - 0.00067 19.1 0.8 1 8.8 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 AJW71333.1 - 0.00094 19.3 0.0 0.0057 16.8 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AJW71333.1 - 0.0011 19.3 4.6 0.0012 19.1 0.2 3.0 3 2 0 3 3 2 1 AAA domain AAA_16 PF13191.1 AJW71333.1 - 0.0013 18.7 0.1 0.0053 16.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 AJW71333.1 - 0.0026 17.1 0.2 0.0069 15.7 0.2 1.7 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 AJW71333.1 - 0.0032 17.3 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 AJW71333.1 - 0.0048 15.9 0.0 0.0087 15.1 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase NTPase_1 PF03266.10 AJW71333.1 - 0.0056 16.4 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_10 PF12846.2 AJW71333.1 - 0.007 15.8 0.4 0.013 14.9 0.1 1.7 1 1 1 2 2 2 1 AAA-like domain AAA_5 PF07728.9 AJW71333.1 - 0.0084 15.8 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LpxK PF02606.9 AJW71333.1 - 0.0089 15.0 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase AAA_26 PF13500.1 AJW71333.1 - 0.011 15.4 0.1 0.16 11.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AJW71333.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 AJW71333.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MipZ PF09140.6 AJW71333.1 - 0.013 14.5 0.3 0.24 10.4 0.2 2.2 1 1 0 1 1 1 0 ATPase MipZ ABC_tran PF00005.22 AJW71333.1 - 0.016 15.4 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 AJW71333.1 - 0.019 14.4 1.4 0.17 11.2 1.0 2.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 AJW71333.1 - 0.019 14.1 0.3 0.22 10.7 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 AJW71333.1 - 0.023 14.4 0.1 0.065 12.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 AJW71333.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.12 AJW71333.1 - 0.026 14.0 0.1 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 AJW71333.1 - 0.032 13.6 0.2 0.094 12.1 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 AJW71333.1 - 0.034 14.1 0.2 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AJW71333.1 - 0.039 13.7 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit LytR_C PF13399.1 AJW71333.1 - 0.04 14.2 0.1 0.098 13.0 0.1 1.7 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator SpoVIF PF14069.1 AJW71333.1 - 0.046 13.4 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 Stage VI sporulation protein F VirC1 PF07015.6 AJW71333.1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein EIF_2_alpha PF07541.7 AJW71333.1 - 0.067 12.9 0.1 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Cytidylate_kin2 PF13189.1 AJW71333.1 - 0.095 12.5 0.9 13 5.6 0.1 3.2 3 1 0 3 3 3 0 Cytidylate kinase-like family Mur_ligase_M PF08245.7 AJW71333.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Mur ligase middle domain DUF3562 PF12085.3 AJW71333.1 - 0.11 12.3 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) AAA_24 PF13479.1 AJW71333.1 - 0.13 11.8 1.2 0.3 10.6 0.3 2.1 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 AJW71333.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.7 AJW71333.1 - 0.28 10.8 2.2 0.25 11.0 0.3 1.8 2 0 0 2 2 1 0 NACHT domain ATP_bind_4 PF01902.12 AJW71334.1 - 2.8e-55 187.0 0.0 3.4e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 ATP-binding region Asn_synthase PF00733.16 AJW71334.1 - 1.3e-05 24.7 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AJW71334.1 - 0.0014 17.9 0.0 0.003 16.8 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AJW71334.1 - 0.029 12.9 0.0 0.057 11.9 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase TGT PF01702.13 AJW71334.1 - 0.073 12.3 0.0 0.095 11.9 0.0 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase PAPS_reduct PF01507.14 AJW71334.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family eIF-5a PF01287.15 AJW71335.1 - 7.2e-14 51.4 3.0 9.5e-14 51.0 2.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 AJW71335.1 - 1.8e-05 24.5 0.1 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 AJW71335.1 - 0.017 14.8 0.3 0.59 9.9 0.0 2.6 2 0 0 2 2 2 0 KOW motif PI3_PI4_kinase PF00454.22 AJW71336.1 - 0.044 13.2 0.8 6.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase CSD PF00313.17 AJW71337.1 - 1.7e-21 75.7 3.9 2.1e-21 75.4 2.7 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 AJW71337.1 - 9.9e-07 28.1 1.2 1e-06 28.1 0.8 1.1 1 0 0 1 1 1 1 Ribonuclease B OB domain Antitoxin-MazE PF04014.13 AJW71337.1 - 0.2 11.3 0.9 0.5 10.1 0.6 1.8 1 1 0 1 1 1 0 Antidote-toxin recognition MazE eIF-1a PF01176.14 AJW71338.1 - 1.5e-20 72.3 1.5 1.9e-20 72.0 1.0 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CxxCxxCC PF03692.10 AJW71339.1 - 1.7e-10 41.2 1.1 4e-10 40.0 0.7 1.7 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain HTH_AsnC-type PF13404.1 AJW71340.1 - 1.5e-09 37.1 0.8 1.6e-08 33.9 0.6 2.4 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AJW71340.1 - 1.8e-09 36.8 1.5 1.8e-09 36.8 1.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_12 PF08461.5 AJW71340.1 - 9.5e-08 31.6 0.5 2.3e-07 30.4 0.2 1.7 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_11 PF08279.7 AJW71340.1 - 3e-06 26.7 0.7 1.4e-05 24.6 0.5 2.1 1 1 0 1 1 1 1 HTH domain HTH_Tnp_Tc3_2 PF01498.13 AJW71340.1 - 2.7e-05 24.1 0.2 9e-05 22.4 0.1 1.9 2 0 0 2 2 1 1 Transposase HTH_20 PF12840.2 AJW71340.1 - 0.00016 21.4 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Penicillinase_R PF03965.11 AJW71340.1 - 0.00017 21.6 0.3 0.00061 19.8 0.0 1.9 2 0 0 2 2 2 1 Penicillinase repressor HTH_DeoR PF08220.7 AJW71340.1 - 0.0018 17.7 0.1 0.0055 16.2 0.1 1.8 1 1 0 1 1 1 1 DeoR-like helix-turn-helix domain Myb_DNA-bind_4 PF13837.1 AJW71340.1 - 0.0074 16.3 0.1 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain FUR PF01475.14 AJW71340.1 - 0.018 14.9 0.3 0.035 14.0 0.0 1.5 2 0 0 2 2 1 0 Ferric uptake regulator family HTH_32 PF13565.1 AJW71340.1 - 0.02 15.6 0.0 0.083 13.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Arg_repressor PF01316.16 AJW71340.1 - 0.021 14.3 0.1 0.054 13.0 0.1 1.7 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain RPA_C PF08784.6 AJW71340.1 - 0.025 14.9 0.1 0.085 13.2 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal COG5 PF10392.4 AJW71340.1 - 0.047 13.6 0.4 0.097 12.6 0.3 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3783 PF12646.2 AJW71340.1 - 0.055 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Sigma70_r4_2 PF08281.7 AJW71340.1 - 0.063 12.7 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2203 PF09969.4 AJW71340.1 - 0.066 13.4 0.5 0.2 11.8 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4358 PF14270.1 AJW71340.1 - 0.079 12.8 1.1 0.32 10.8 0.1 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4358) DUF3658 PF12395.3 AJW71340.1 - 0.098 12.2 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function Rrf2 PF02082.15 AJW71340.1 - 0.11 12.6 0.1 0.94 9.6 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator DUF2862 PF11061.3 AJW71340.1 - 3 7.6 7.6 1.5 8.5 0.2 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2862) Response_reg PF00072.19 AJW71341.1 - 1e-16 60.9 0.1 1.5e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain TPR_2 PF07719.12 AJW71341.1 - 0.00013 21.6 0.3 0.0021 17.8 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AJW71341.1 - 0.00043 20.3 8.2 0.032 14.3 0.4 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AJW71341.1 - 0.00056 19.4 0.6 0.0033 16.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AJW71341.1 - 0.00082 18.9 0.3 0.0069 16.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AJW71341.1 - 0.0019 18.0 1.1 0.051 13.5 0.0 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat tRNA_synt_1c_R1 PF04558.10 AJW71341.1 - 0.019 14.4 0.3 0.045 13.2 0.2 1.6 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 TPR_11 PF13414.1 AJW71341.1 - 0.048 13.2 2.6 2.4 7.8 0.1 2.5 1 1 0 2 2 2 0 TPR repeat TPR_19 PF14559.1 AJW71341.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SCO1-SenC PF02630.9 AJW71341.1 - 0.24 11.0 5.6 5.2 6.6 0.1 2.5 2 1 0 2 2 2 0 SCO1/SenC TPR_6 PF13174.1 AJW71341.1 - 0.41 11.2 1.5 2 9.0 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ADH_N PF08240.7 AJW71342.1 - 8.8e-33 112.3 0.3 1.5e-32 111.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJW71342.1 - 5.3e-30 103.6 0.4 7.6e-30 103.1 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AJW71342.1 - 9.2e-10 39.5 0.1 1.8e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AJW71342.1 - 0.0039 16.7 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 AJW71342.1 - 0.02 14.9 0.2 0.064 13.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain SDH_sah PF01972.11 AJW71342.1 - 0.087 11.5 0.1 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ScpA_ScpB PF02616.9 AJW71343.1 - 1.9e-13 50.5 3.3 8.5e-07 28.8 0.5 2.1 2 0 0 2 2 2 2 ScpA/B protein DUF387 PF04079.11 AJW71344.1 - 4.4e-35 120.4 0.4 5.3e-35 120.1 0.3 1.1 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) HHH_3 PF12836.2 AJW71344.1 - 0.046 13.6 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix motif HTH_20 PF12840.2 AJW71344.1 - 0.11 12.3 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S8e PF01201.17 AJW71345.1 - 4.5e-24 85.0 4.0 4.9e-24 84.9 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L22 PF00237.14 AJW71345.1 - 0.074 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e PHB_acc_N PF07879.6 AJW71345.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain SRP19 PF01922.12 AJW71346.1 - 4.5e-16 59.2 0.0 5.2e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 SRP19 protein Ku PF02735.11 AJW71346.1 - 0.014 14.8 0.1 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain Streptin-Immun PF11083.3 AJW71346.1 - 0.068 13.1 0.1 7.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Gar1 PF04410.9 AJW71347.1 - 1.6e-08 34.1 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region TFIIB PF00382.14 AJW71348.1 - 1e-24 86.0 2.3 1e-11 44.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW71348.1 - 1.5e-11 43.3 2.6 1.5e-11 43.3 1.8 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RPA_interact_C PF14768.1 AJW71348.1 - 0.021 15.2 1.7 1.3 9.4 0.0 2.8 2 1 0 2 2 2 0 Replication protein A interacting C-terminal Cys_knot PF00007.17 AJW71348.1 - 0.059 13.4 0.9 0.059 13.4 0.6 2.2 2 0 0 2 2 2 0 Cystine-knot domain zinc-ribbons_6 PF07191.7 AJW71348.1 - 0.073 12.8 2.7 0.23 11.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 AJW71348.1 - 0.1 12.2 2.0 0.16 11.6 0.4 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 AJW71348.1 - 0.29 10.9 4.2 0.24 11.2 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.7 AJW71348.1 - 1.7 8.4 6.1 0.24 11.1 1.0 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Spt4 PF06093.8 AJW71348.1 - 2.2 8.2 8.7 1.6 8.6 0.8 3.3 3 2 0 3 3 3 0 Spt4/RpoE2 zinc finger ABC_tran PF00005.22 AJW71349.1 - 2.9e-20 72.9 0.0 4.3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJW71349.1 - 6.2e-11 42.7 0.1 1.1e-09 38.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AJW71349.1 - 7.2e-11 41.7 0.4 5.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AJW71349.1 - 0.0002 20.8 0.5 0.0012 18.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AJW71349.1 - 0.00032 20.6 0.0 0.00044 20.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AJW71349.1 - 0.00081 19.4 0.1 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 AJW71349.1 - 0.00097 18.6 1.1 0.0012 18.2 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 AJW71349.1 - 0.0024 17.7 0.0 0.0085 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 AJW71349.1 - 0.0034 15.9 0.3 0.12 10.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AJW71349.1 - 0.0057 16.8 0.3 0.13 12.4 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MutS_V PF00488.16 AJW71349.1 - 0.0064 15.9 0.1 2.6 7.3 0.0 2.1 2 0 0 2 2 2 2 MutS domain V AAA_23 PF13476.1 AJW71349.1 - 0.0068 16.7 0.8 0.025 14.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AJW71349.1 - 0.011 16.0 1.2 0.88 9.8 0.9 2.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AJW71349.1 - 0.015 16.1 0.3 0.037 14.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AJW71349.1 - 0.016 15.1 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 AJW71349.1 - 0.021 14.5 0.6 0.17 11.5 0.1 2.0 1 1 1 2 2 2 0 Archaeal ATPase ArgK PF03308.11 AJW71349.1 - 0.04 12.6 0.1 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_22 PF13401.1 AJW71349.1 - 0.07 13.2 0.1 0.15 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AJW71349.1 - 0.075 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 AJW71349.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA helicase DUF167 PF02594.11 AJW71350.1 - 3.4e-14 52.5 2.4 3.7e-14 52.3 1.7 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 SUI1 PF01253.17 AJW71350.1 - 0.035 13.8 1.5 0.053 13.3 1.0 1.5 1 1 0 1 1 1 0 Translation initiation factor SUI1 SpoIIID PF12116.3 AJW71350.1 - 0.076 12.9 0.2 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_7 PF02796.10 AJW71350.1 - 0.12 12.3 0.3 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase Chlor_dismutase PF06778.7 AJW71351.1 - 3.1e-51 173.8 0.5 3.7e-51 173.6 0.3 1.0 1 0 0 1 1 1 1 Chlorite dismutase AsnC_trans_reg PF01037.16 AJW71351.1 - 0.11 12.1 1.7 11 5.8 0.0 2.5 2 1 0 2 2 2 0 AsnC family Aldo_ket_red PF00248.16 AJW71352.1 - 2.4e-49 167.6 0.1 2.7e-49 167.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FB_lectin PF07367.6 AJW71353.1 - 0.027 14.0 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 Fungal fruit body lectin zf-B_box PF00643.19 AJW71353.1 - 0.036 13.9 2.1 0.051 13.4 1.5 1.3 1 0 0 1 1 1 0 B-box zinc finger HTH_AsnC-type PF13404.1 AJW71354.1 - 0.00021 20.7 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 AJW71354.1 - 0.0012 18.1 0.2 0.011 15.1 0.1 2.4 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 AJW71354.1 - 0.0091 15.6 0.0 2.4 7.9 0.0 3.4 3 1 0 3 3 3 1 AsnC family DUF2316 PF10078.4 AJW71354.1 - 0.011 15.7 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF262 PF03235.9 AJW71354.1 - 0.047 13.6 0.7 0.07 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF262 NAD_binding_7 PF13241.1 AJW71355.1 - 5.2e-21 74.8 2.7 2.8e-20 72.4 0.2 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 AJW71355.1 - 1.5e-05 25.0 1.4 1.6e-05 24.9 0.2 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 AJW71355.1 - 0.0061 16.9 0.8 0.022 15.1 0.2 2.3 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sirohm_synth_M PF14824.1 AJW71355.1 - 0.0085 15.0 0.0 0.035 13.0 0.0 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 AJW71355.1 - 0.021 14.8 0.6 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain THF_DHG_CYH_C PF02882.14 AJW71355.1 - 0.03 13.3 0.1 0.054 12.5 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 AJW71355.1 - 0.058 12.0 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase RibD_C PF01872.12 AJW71355.1 - 0.065 12.8 0.2 0.098 12.2 0.1 1.4 1 1 0 1 1 1 0 RibD C-terminal domain CysG_dimeriser PF10414.4 AJW71355.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region ELFV_dehydrog PF00208.16 AJW71355.1 - 0.18 11.3 0.1 0.18 11.3 0.0 1.7 2 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2775 PF10950.3 AJW71355.1 - 2.6 8.3 9.8 2.5 8.3 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2775) GlutR_N PF05201.10 AJW71356.1 - 2.3e-41 140.9 1.6 2.5e-41 140.7 0.2 1.7 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 AJW71356.1 - 1.2e-22 80.5 0.0 3.5e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.15 AJW71356.1 - 5.9e-21 74.3 2.6 1.2e-20 73.2 1.8 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain 2-Hacid_dh_C PF02826.14 AJW71356.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LVIVD PF08309.6 AJW71356.1 - 0.15 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 LVIVD repeat DUF1664 PF07889.7 AJW71356.1 - 1.3 8.8 12.0 6.2 6.6 0.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ALAD PF00490.16 AJW71357.1 - 5.1e-134 446.2 1.1 5.8e-134 446.0 0.8 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF2070 PF09843.4 AJW71357.1 - 1.5e-06 27.7 0.1 3.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) JmjN PF02375.12 AJW71358.1 - 0.02 14.4 7.8 0.07 12.6 2.1 2.3 1 1 1 2 2 2 0 jmjN domain DUF4546 PF15079.1 AJW71358.1 - 0.8 8.8 3.4 0.96 8.5 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) SNARE_assoc PF09335.6 AJW71359.1 - 6.9e-05 23.0 7.1 0.00013 22.1 4.9 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF751 PF05421.6 AJW71359.1 - 0.45 10.8 0.1 0.45 10.8 0.0 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF751) 7tm_4 PF13853.1 AJW71361.1 - 0.077 12.7 0.3 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Olfactory receptor DUF2371 PF10177.4 AJW71361.1 - 0.54 10.1 2.0 1.9 8.3 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF2618 PF10940.3 AJW71361.1 - 0.58 9.9 2.2 0.57 9.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) SHP PF03579.8 AJW71361.1 - 6.6 6.1 8.9 1.5 8.2 0.6 2.4 2 0 0 2 2 2 0 Small hydrophobic protein HC2 PF07382.6 AJW71363.1 - 9.7e-14 51.6 123.1 9.7e-14 51.6 85.4 1.6 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 MscS_porin PF12795.2 AJW71364.1 - 0.00047 19.5 22.6 0.00063 19.1 15.7 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 AJW71364.1 - 0.0016 16.9 23.7 0.0029 16.1 16.4 1.3 1 1 0 1 1 1 1 AAA domain Tropomyosin PF00261.15 AJW71364.1 - 0.012 14.7 27.0 0.015 14.3 18.7 1.2 1 0 0 1 1 1 0 Tropomyosin DUF745 PF05335.8 AJW71364.1 - 0.016 14.7 20.3 0.014 14.9 7.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CorA PF01544.13 AJW71364.1 - 0.027 13.4 8.3 0.037 13.0 5.7 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein COG2 PF06148.6 AJW71364.1 - 0.03 14.1 18.5 0.06 13.2 4.8 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FliJ PF02050.11 AJW71364.1 - 0.031 14.3 1.0 0.031 14.3 0.7 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein MCPsignal PF00015.16 AJW71364.1 - 0.039 13.4 16.7 0.035 13.6 4.4 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.7 AJW71364.1 - 0.053 13.3 5.3 0.055 13.2 2.7 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 AJW71364.1 - 0.078 12.5 29.6 5.3 6.5 20.5 2.1 1 1 0 1 1 1 0 IncA protein DASH_Duo1 PF08651.5 AJW71364.1 - 0.16 11.5 12.3 0.83 9.2 0.2 3.2 2 1 2 4 4 4 0 DASH complex subunit Duo1 Reo_sigmaC PF04582.7 AJW71364.1 - 0.29 10.2 7.9 1.4 7.9 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 AJW71364.1 - 0.35 9.4 29.8 0.39 9.3 13.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein HAUS5 PF14817.1 AJW71364.1 - 0.44 9.0 18.5 0.59 8.6 12.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF1664 PF07889.7 AJW71364.1 - 0.45 10.3 17.4 4.5 7.1 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 AJW71364.1 - 0.46 10.7 12.7 0.4 10.9 1.5 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Hex_IIIa PF02455.11 AJW71364.1 - 0.51 8.9 11.4 0.59 8.7 7.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Tropomyosin_1 PF12718.2 AJW71364.1 - 0.75 9.6 30.9 1.4 8.7 14.5 2.3 1 1 1 2 2 2 0 Tropomyosin like HHA PF05321.6 AJW71364.1 - 0.9 9.7 4.3 6.3 7.0 0.2 3.0 2 1 1 3 3 3 0 Haemolysin expression modulating protein Flagellin_C PF00700.16 AJW71364.1 - 1.2 9.3 6.0 0.65 10.2 1.6 2.2 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region zf-C4H2 PF10146.4 AJW71364.1 - 1.2 9.0 23.1 3.3 7.6 8.8 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Allexi_40kDa PF05549.6 AJW71364.1 - 1.4 8.1 16.2 0.93 8.7 3.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein ATG16 PF08614.6 AJW71364.1 - 1.5 8.6 25.8 6.1 6.6 17.9 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 AJW71364.1 - 1.5 6.0 26.0 2.6 5.2 18.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin_2 PF14523.1 AJW71364.1 - 1.5 8.8 20.7 18 5.4 3.7 3.0 1 1 1 2 2 2 0 Syntaxin-like protein FIST_C PF10442.4 AJW71364.1 - 1.8 8.5 4.4 2.2 8.2 1.0 2.1 1 1 1 2 2 2 0 FIST C domain CDC37_N PF03234.9 AJW71364.1 - 2.5 8.3 22.8 4.3 7.6 15.5 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF883 PF05957.8 AJW71364.1 - 2.9 8.3 19.3 2.4 8.6 2.4 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TMF_DNA_bd PF12329.3 AJW71364.1 - 3.1 7.6 33.6 0.32 10.8 6.6 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 AJW71364.1 - 3.3 7.8 19.9 2.3 8.3 8.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3552 PF12072.3 AJW71364.1 - 4.8 6.3 30.4 1.2 8.3 13.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF641 PF04859.7 AJW71364.1 - 5.2 6.8 22.6 2 8.1 2.3 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) CP12 PF02672.10 AJW71364.1 - 6 7.4 16.9 0.2 12.1 3.8 3.0 2 1 1 3 3 3 0 CP12 domain DUF812 PF05667.6 AJW71364.1 - 6 5.2 25.6 10 4.5 17.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4460 PF14687.1 AJW71364.1 - 7.3 6.3 11.2 0.3 10.8 0.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4460) PAP2 PF01569.16 AJW71366.1 - 1.2e-21 76.7 0.7 1.2e-21 76.7 0.5 2.0 1 1 1 2 2 2 2 PAP2 superfamily PAP2_C PF14360.1 AJW71366.1 - 5.1e-05 23.4 0.2 5.1e-05 23.4 0.1 2.8 3 1 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 AJW71366.1 - 0.00011 21.7 2.8 0.00011 21.7 2.0 2.1 1 1 0 1 1 1 1 PAP2 superfamily PGK PF00162.14 AJW71367.1 - 8.2e-110 366.9 0.2 9.4e-110 366.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF218 PF02698.12 AJW71367.1 - 0.0038 16.7 0.2 0.74 9.2 0.0 2.4 2 0 0 2 2 2 2 DUF218 domain CbiA PF01656.18 AJW71367.1 - 0.0042 16.5 0.1 0.79 9.0 0.0 2.3 1 1 1 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1033 PF06279.6 AJW71368.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) PqqD PF05402.7 AJW71368.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) NifU_N PF01592.11 AJW71369.1 - 4.2e-30 104.3 0.1 4.8e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Aminotran_5 PF00266.14 AJW71370.1 - 8.7e-149 495.2 0.7 9.8e-149 495.1 0.5 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AJW71370.1 - 2.8e-06 26.5 0.1 4.5e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AJW71370.1 - 0.00021 20.5 0.1 0.00031 20.0 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase DUF4582 PF15189.1 AJW71370.1 - 0.043 13.0 1.4 2.4 7.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) Rieske PF00355.21 AJW71371.1 - 4.5e-17 61.3 0.0 5.1e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AJW71371.1 - 2.1e-12 46.6 0.0 2.4e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0051 PF01458.12 AJW71372.1 - 8.7e-66 221.6 1.5 1.4e-65 221.0 1.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF2152 PF10222.4 AJW71372.1 - 0.0033 15.7 0.0 0.0058 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) UPF0051 PF01458.12 AJW71373.1 - 3.7e-70 235.9 0.2 4.9e-70 235.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF1307 PF06998.6 AJW71373.1 - 0.28 11.2 3.0 4.8 7.2 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1307) HEM4 PF02602.10 AJW71374.1 - 2.8e-42 144.5 0.0 3.2e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TP_methylase PF00590.15 AJW71375.1 - 1.8e-48 165.0 0.0 2.1e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA_int_endo PF01974.12 AJW71375.1 - 0.047 13.4 0.1 0.26 11.1 0.1 2.2 1 1 1 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain Aminotran_3 PF00202.16 AJW71376.1 - 7e-71 238.8 0.1 8.5e-71 238.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AJW71376.1 - 5.8e-06 25.5 0.0 9.1e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1_N PF03709.10 AJW71376.1 - 0.094 12.7 0.0 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain z-alpha PF02295.12 AJW71376.1 - 0.098 12.4 0.4 0.32 10.7 0.1 2.1 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain zf-ribbon_3 PF13248.1 AJW71378.1 - 3.2e-05 22.9 3.9 0.003 16.6 0.3 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-MYND PF01753.13 AJW71378.1 - 0.063 13.1 0.6 0.16 11.8 0.4 1.6 1 1 0 1 1 1 0 MYND finger Zn-ribbon_8 PF09723.5 AJW71378.1 - 0.094 12.6 3.3 0.11 12.4 2.3 1.2 1 0 0 1 1 1 0 Zinc ribbon domain zf-FPG_IleRS PF06827.9 AJW71378.1 - 0.33 10.6 4.9 1.2 8.8 0.2 2.7 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS eIF-5_eIF-2B PF01873.12 AJW71378.1 - 0.41 10.3 3.2 0.47 10.1 2.2 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 DZR PF12773.2 AJW71378.1 - 1.2 8.9 5.7 5.9 6.7 3.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 AJW71378.1 - 6.5 6.3 13.7 13 5.4 0.8 3.0 2 1 0 2 2 2 0 zinc-ribbon domain PyrI_C PF02748.10 AJW71378.1 - 6.5 6.2 7.3 3.8 7.0 1.2 2.4 1 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain MIP PF00230.15 AJW71380.1 - 1.3e-36 126.2 20.0 1.6e-36 125.8 13.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phenol_MetA_deg PF13557.1 AJW71380.1 - 0.35 10.6 2.3 0.44 10.3 0.8 1.7 1 1 0 1 1 1 0 Putative MetA-pathway of phenol degradation LMWPc PF01451.16 AJW71381.1 - 1.3e-16 61.2 0.1 1.8e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase HTH_5 PF01022.15 AJW71382.1 - 5.2e-16 58.0 0.2 9.5e-16 57.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJW71382.1 - 1.5e-09 37.4 0.0 2.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AJW71382.1 - 6.1e-07 28.7 0.2 2e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJW71382.1 - 6.4e-05 22.5 0.3 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.1 AJW71382.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.3 1 1 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 AJW71382.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TBPIP PF07106.8 AJW71382.1 - 0.0069 15.9 0.3 0.0079 15.7 0.2 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TFIIE_alpha PF02002.12 AJW71382.1 - 0.0077 15.7 0.2 0.0099 15.3 0.2 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit DUF483 PF04467.7 AJW71382.1 - 0.023 14.7 0.2 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF483) Penicillinase_R PF03965.11 AJW71382.1 - 0.027 14.5 0.2 0.037 14.1 0.1 1.3 1 0 0 1 1 1 0 Penicillinase repressor MarR_2 PF12802.2 AJW71382.1 - 0.035 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 MarR family DltD_M PF04918.7 AJW71382.1 - 0.079 13.1 0.2 0.091 12.9 0.1 1.0 1 0 0 1 1 1 0 DltD central region Rrf2 PF02082.15 AJW71382.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Transcriptional regulator Cdc6_C PF09079.6 AJW71382.1 - 0.11 12.2 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal HTH_IclR PF09339.5 AJW71382.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain Arg_repressor PF01316.16 AJW71382.1 - 0.13 11.8 0.2 0.33 10.5 0.1 1.8 1 1 0 1 1 1 0 Arginine repressor, DNA binding domain P-II PF00543.17 AJW71383.1 - 0.00015 22.2 0.4 0.00019 21.8 0.3 1.3 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.3 AJW71383.1 - 0.00084 19.2 0.2 0.0027 17.6 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3240) DUF190 PF02641.10 AJW71383.1 - 0.043 13.6 0.6 0.053 13.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 PurS PF02700.9 AJW71383.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Rad1 PF02144.11 AJW71383.1 - 0.094 11.4 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 DUF897 PF05982.7 AJW71384.1 - 3.3e-91 305.4 21.9 4e-91 305.2 15.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF897) NHL PF01436.16 AJW71386.1 - 9.1e-39 129.4 0.9 2.4e-09 36.6 0.0 7.0 7 0 0 7 7 7 6 NHL repeat SGL PF08450.7 AJW71386.1 - 8.7e-14 51.4 0.9 1.8e-05 24.2 0.1 3.9 2 2 1 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 AJW71386.1 - 3.3e-07 29.9 18.1 0.00099 18.8 0.4 5.8 6 0 0 6 6 6 3 Beta-propeller repeat HYR PF02494.11 AJW71386.1 - 1.8e-05 24.6 0.0 6.4e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 HYR domain HemolysinCabind PF00353.14 AJW71386.1 - 0.00058 19.9 46.8 0.013 15.8 6.0 6.1 3 1 2 6 6 6 4 Hemolysin-type calcium-binding repeat (2 copies) Str_synth PF03088.11 AJW71386.1 - 0.00093 19.1 0.1 2.5 8.2 0.0 4.1 4 0 0 4 4 4 1 Strictosidine synthase LVIVD PF08309.6 AJW71386.1 - 0.0074 15.2 0.1 0.0074 15.2 0.1 3.5 4 0 0 4 4 4 1 LVIVD repeat PQQ_3 PF13570.1 AJW71386.1 - 0.0097 16.1 9.1 3.2 8.1 0.0 5.5 6 0 0 6 6 6 1 PQQ-like domain Big_3_4 PF13754.1 AJW71386.1 - 0.028 14.7 0.1 0.13 12.6 0.1 2.2 2 0 0 2 2 1 0 Bacterial Ig-like domain (group 3) Ldl_recept_b PF00058.12 AJW71386.1 - 0.048 13.9 0.0 58 4.1 0.0 4.2 3 2 0 3 3 3 0 Low-density lipoprotein receptor repeat class B Big_3_2 PF12245.3 AJW71386.1 - 0.055 13.0 0.8 0.59 9.7 0.0 3.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ABC2_membrane PF01061.19 AJW71387.1 - 4.9e-34 117.3 17.6 4.9e-34 117.3 12.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AJW71387.1 - 3.6e-16 59.1 29.9 4.5e-16 58.8 20.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 AJW71387.1 - 3.4e-10 39.4 23.6 4.1e-10 39.2 16.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 AJW71387.1 - 7.9e-07 28.2 23.2 1.6e-06 27.1 16.1 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 AJW71388.1 - 8.2e-31 107.1 0.0 1.8e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJW71388.1 - 6e-11 42.8 6.5 6.4e-08 32.9 0.2 2.7 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.1 AJW71388.1 - 0.0002 20.5 0.1 0.0002 20.5 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.1 AJW71388.1 - 0.00023 21.5 0.4 0.00052 20.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_29 PF13555.1 AJW71388.1 - 0.0008 18.8 0.2 0.0017 17.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 AJW71388.1 - 0.0077 15.4 0.2 0.027 13.7 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AJW71388.1 - 0.018 15.3 8.7 0.11 12.7 6.0 2.4 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 AJW71388.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 AJW71388.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRC PF05239.11 AJW71389.1 - 7.1e-11 41.8 1.0 0.00024 20.9 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain MCE PF02470.15 AJW71389.1 - 0.00031 20.7 0.1 0.32 11.0 0.0 2.2 2 0 0 2 2 2 2 mce related protein DUF3659 PF12396.3 AJW71389.1 - 0.098 12.3 0.2 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) DUF385 PF04075.9 AJW71390.1 - 4.8e-10 39.4 0.0 5.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF385) DUF2255 PF10012.4 AJW71390.1 - 0.00027 20.8 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) Pyridox_oxidase PF01243.15 AJW71390.1 - 0.0055 16.7 0.1 0.031 14.2 0.1 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HTH_5 PF01022.15 AJW71391.1 - 1.6e-08 34.0 0.3 3.7e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 AJW71391.1 - 2.7e-08 33.0 0.4 6.1e-08 31.9 0.3 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 AJW71391.1 - 4.1e-08 32.8 0.0 6.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 AJW71391.1 - 2.4e-05 23.9 0.1 5.8e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 AJW71391.1 - 7.2e-05 22.3 2.5 0.00047 19.7 0.7 2.5 2 0 0 2 2 2 1 HTH domain TFIIE_alpha PF02002.12 AJW71391.1 - 0.0001 21.7 1.7 0.00014 21.2 0.4 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_34 PF13601.1 AJW71391.1 - 0.005 16.8 1.3 0.013 15.5 0.9 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain Sigma70_r4 PF04545.11 AJW71391.1 - 0.0091 15.2 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.2 AJW71391.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_9 PF08221.6 AJW71391.1 - 0.017 14.9 0.1 0.042 13.7 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_45 PF14947.1 AJW71391.1 - 0.024 14.4 1.3 0.046 13.5 0.9 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix Sigma70_r4_2 PF08281.7 AJW71391.1 - 0.028 13.8 0.1 0.069 12.6 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_27 PF13463.1 AJW71391.1 - 0.056 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2250 PF10007.4 AJW71391.1 - 0.069 13.0 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Rrf2 PF02082.15 AJW71391.1 - 0.088 12.9 0.9 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator B-block_TFIIIC PF04182.7 AJW71391.1 - 0.19 11.6 3.9 0.15 11.8 1.4 1.9 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Beta_propel PF09826.4 AJW71392.1 - 4.2e-169 563.2 11.9 5.2e-169 562.9 8.2 1.1 1 0 0 1 1 1 1 Beta propeller domain LVIVD PF08309.6 AJW71392.1 - 0.12 11.3 2.9 5.4 6.0 0.1 3.3 3 0 0 3 3 3 0 LVIVD repeat Glyco_transf_90 PF05686.7 AJW71393.1 - 0.065 11.9 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Toxin_64 PF15542.1 AJW71394.1 - 0.0069 16.9 0.8 2.1 8.9 0.0 2.1 1 1 1 2 2 2 2 Putative toxin 64 HTH_Tnp_Tc5 PF03221.11 AJW71394.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain TPR_11 PF13414.1 AJW71395.1 - 5.6e-15 54.7 0.3 1.1e-06 28.1 0.0 2.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 AJW71395.1 - 1.2e-12 46.8 2.0 3.4e-05 23.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AJW71395.1 - 6.4e-12 44.4 0.4 0.0013 18.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AJW71395.1 - 3.6e-11 42.8 0.1 8.5e-05 22.4 0.0 2.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 AJW71395.1 - 4.5e-10 39.7 0.2 3.7e-07 30.3 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AJW71395.1 - 4.6e-09 35.4 0.0 0.00097 18.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AJW71395.1 - 8.3e-09 35.3 0.0 0.0026 18.2 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AJW71395.1 - 6e-08 31.9 0.1 0.12 12.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AJW71395.1 - 1.1e-07 31.8 0.1 2e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AJW71395.1 - 2e-07 30.6 0.4 0.053 13.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 AJW71395.1 - 2e-06 28.3 0.0 0.012 16.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 AJW71395.1 - 0.0022 17.1 0.0 0.015 14.3 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AJW71395.1 - 0.0024 17.6 1.2 0.048 13.5 0.2 2.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 AJW71395.1 - 0.0079 16.5 0.0 19 5.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 AJW71395.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.13 AJW71395.1 - 0.027 14.3 0.5 0.056 13.3 0.1 1.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Metallothio PF00131.15 AJW71398.1 - 0.01 15.6 14.0 0.01 15.6 9.7 1.9 1 1 1 2 2 2 0 Metallothionein VESA1_N PF12785.2 AJW71398.1 - 1.1 8.1 14.6 1.1 8.1 10.1 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 DUF325 PF03804.8 AJW71400.1 - 0.051 13.2 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Viral domain of unknown function Med2 PF11214.3 AJW71400.1 - 0.089 12.8 1.0 0.19 11.7 0.4 1.8 1 1 1 2 2 2 0 Mediator complex subunit 2 tRNA_int_endo PF01974.12 AJW71401.1 - 1.4e-19 69.6 0.2 4.6e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AJW71401.1 - 1.2e-10 40.7 2.6 2.9e-09 36.3 0.2 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Ribosomal_L16 PF00252.13 AJW71402.1 - 2.1e-22 79.2 1.3 2.7e-22 78.9 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ssDNA-exonuc_C PF10141.4 AJW71403.1 - 0.027 13.9 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain Dioxygenase_N PF04444.9 AJW71403.1 - 0.069 13.1 0.1 7.9 6.5 0.0 2.1 1 1 1 2 2 2 0 Catechol dioxygenase N terminus YmgB PF10798.3 AJW71403.1 - 0.11 12.3 0.8 0.21 11.4 0.5 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR JmjN PF02375.12 AJW71403.1 - 0.15 11.6 0.3 0.35 10.4 0.2 1.6 1 0 0 1 1 1 0 jmjN domain Na_H_Exchanger PF00999.16 AJW71405.1 - 1.3e-56 191.7 57.9 1.7e-56 191.4 40.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YabQ PF09578.5 AJW71405.1 - 0.061 13.2 0.2 0.061 13.2 0.2 4.0 4 2 0 4 4 4 0 Spore cortex protein YabQ (Spore_YabQ) DUF1664 PF07889.7 AJW71406.1 - 0.001 18.8 38.5 0.011 15.4 1.0 5.3 1 1 4 5 5 5 3 Protein of unknown function (DUF1664) MCPsignal PF00015.16 AJW71406.1 - 0.051 13.1 42.5 0.23 10.9 4.1 4.9 1 1 4 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 AJW71406.1 - 0.074 13.3 0.5 0.074 13.3 0.4 7.0 2 1 6 8 8 8 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 AJW71406.1 - 0.18 11.5 39.3 0.28 10.9 1.8 4.6 1 1 4 6 6 6 0 Laminin Domain II DUF869 PF05911.6 AJW71406.1 - 0.18 9.9 43.3 0.41 8.8 23.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF948 PF06103.6 AJW71406.1 - 0.28 11.0 32.4 0.77 9.6 0.1 6.0 2 2 4 6 6 6 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.3 AJW71406.1 - 0.3 11.1 18.7 0.52 10.3 1.8 5.2 1 1 4 6 6 6 0 AT-hook-containing transcription factor Spc7 PF08317.6 AJW71406.1 - 0.54 8.8 47.2 0.37 9.4 4.8 3.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Allexi_40kDa PF05549.6 AJW71406.1 - 2.1 7.5 32.2 0.2 10.9 4.8 4.5 1 1 5 6 6 6 0 Allexivirus 40kDa protein Occludin_ELL PF07303.8 AJW71406.1 - 3 8.6 21.4 4.4 8.1 0.2 4.9 1 1 3 5 5 5 0 Occludin homology domain Cauli_AT PF03233.8 AJW71406.1 - 5.8 6.5 41.9 0.081 12.6 1.1 5.0 1 1 4 6 6 6 0 Aphid transmission protein Glyco_tranf_2_3 PF13641.1 AJW71407.1 - 1.7e-35 122.8 0.0 2.4e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AJW71407.1 - 1.4e-21 77.1 0.3 3.1e-21 75.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 AJW71407.1 - 1.6e-15 57.1 0.1 2.7e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AJW71407.1 - 2.6e-13 49.6 0.1 4.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 AJW71407.1 - 0.00084 18.5 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AJW71407.1 - 0.091 13.0 0.2 1 9.7 0.3 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Fer4 PF00037.22 AJW71409.1 - 4.4e-08 32.3 16.0 0.00014 21.3 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AJW71409.1 - 1.2e-06 28.6 5.0 2.5e-06 27.6 3.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 AJW71409.1 - 1.2e-06 28.7 3.6 2.9e-06 27.5 2.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJW71409.1 - 6.6e-06 25.8 5.7 1.4e-05 24.7 3.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJW71409.1 - 8e-05 22.4 3.4 0.00012 21.7 2.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJW71409.1 - 0.00022 20.9 13.1 0.0035 17.1 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 AJW71409.1 - 0.0009 19.6 2.1 0.62 10.5 0.4 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 AJW71409.1 - 0.0027 17.7 4.6 0.023 14.7 3.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AJW71409.1 - 0.0049 17.1 1.3 2.3 8.6 0.0 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJW71409.1 - 0.0078 16.0 11.0 0.077 12.9 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 AJW71409.1 - 0.053 13.8 5.1 4.1 7.9 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.2 AJW71409.1 - 0.12 12.9 15.1 0.22 12.1 1.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 AJW71409.1 - 0.3 11.6 9.7 0.4 11.2 0.4 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 AJW71409.1 - 0.38 11.5 6.6 4.6 8.0 1.3 2.6 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_13 PF13370.1 AJW71409.1 - 0.67 10.3 8.7 0.75 10.2 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Meth_synt_2 PF01717.13 AJW71410.1 - 0.12 11.2 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Rhodanese PF00581.15 AJW71411.1 - 2.1e-38 131.1 0.1 2.6e-23 82.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NAD_kinase PF01513.16 AJW71412.1 - 1.7e-34 118.9 2.5 2.2e-34 118.5 1.7 1.2 1 0 0 1 1 1 1 ATP-NAD kinase CoA_binding_2 PF13380.1 AJW71412.1 - 0.00072 19.7 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain DAGK_cat PF00781.19 AJW71412.1 - 0.0018 17.7 0.1 0.0036 16.7 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PIN PF01850.16 AJW71413.1 - 3.9e-08 33.6 0.1 5.1e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 PIN domain UPF0278 PF08745.6 AJW71413.1 - 6.3e-06 25.5 0.0 0.00073 18.8 0.0 2.1 2 0 0 2 2 2 2 UPF0278 family DZR PF12773.2 AJW71413.1 - 0.012 15.3 0.9 0.023 14.5 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF4411 PF14367.1 AJW71413.1 - 0.033 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) zf-ribbon_3 PF13248.1 AJW71413.1 - 0.046 12.9 4.8 0.083 12.1 3.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Sar8_2 PF03058.9 AJW71413.1 - 0.048 14.0 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 Sar8.2 family DNA_ligase_ZBD PF03119.11 AJW71413.1 - 0.061 13.0 2.3 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain PIN_2 PF10130.4 AJW71413.1 - 0.11 12.5 0.1 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 PIN domain zinc_ribbon_2 PF13240.1 AJW71413.1 - 2.4 7.7 5.4 45 3.7 3.7 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Rhodanese PF00581.15 AJW71414.1 - 4.7e-31 107.4 0.0 1.5e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain CHASE4 PF05228.8 AJW71414.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 CHASE4 domain ERCC4 PF02732.10 AJW71415.1 - 3.1e-25 88.6 0.0 6.5e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 ERCC4 domain HHH PF00633.18 AJW71415.1 - 3.2e-08 32.8 0.1 0.001 18.6 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 AJW71415.1 - 3.8e-08 33.3 0.0 9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 AJW71415.1 - 6.3e-06 25.9 0.0 6e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.2 AJW71415.1 - 0.00025 20.9 0.0 0.045 13.6 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.1 AJW71415.1 - 0.01 15.9 0.1 1 9.6 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain Prefoldin_2 PF01920.15 AJW71416.1 - 6.8e-21 74.0 22.0 7.6e-21 73.8 15.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit D5_N PF08706.6 AJW71416.1 - 0.0033 17.5 1.5 0.004 17.2 1.1 1.1 1 0 0 1 1 1 1 D5 N terminal like KSR1-SAM PF13543.1 AJW71416.1 - 0.12 12.2 4.2 1.9 8.2 0.5 2.1 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Formyl_trans_N PF00551.14 AJW71416.1 - 0.53 9.7 3.5 4.2 6.8 2.5 1.9 1 1 1 2 2 2 0 Formyl transferase AF0941-like PF14591.1 AJW71416.1 - 0.54 10.3 11.7 4.9 7.2 4.2 2.1 1 1 1 2 2 2 0 AF0941-like NPV_P10 PF05531.7 AJW71416.1 - 0.73 10.1 5.8 1.7 8.9 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3053 PF11254.3 AJW71416.1 - 1.2 8.3 8.4 1.5 8.0 5.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Bac_DNA_binding PF00216.16 AJW71416.1 - 1.2 9.1 7.3 1.7 8.7 1.1 2.2 2 0 0 2 2 2 0 Bacterial DNA-binding protein TPR_MLP1_2 PF07926.7 AJW71416.1 - 1.3 8.8 16.3 2.2 8.0 3.7 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein M_domain PF12938.2 AJW71416.1 - 2 8.1 9.8 2.8 7.7 6.8 1.4 1 1 0 1 1 1 0 M domain of GW182 V_ATPase_I PF01496.14 AJW71416.1 - 4 5.1 7.7 5 4.8 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4559 PF15112.1 AJW71416.1 - 5.7 6.0 10.7 7.4 5.6 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF342 PF03961.8 AJW71416.1 - 5.8 5.2 13.5 7.2 4.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sld5 PF05916.6 AJW71416.1 - 6.6 7.0 6.4 13 6.1 4.4 1.7 1 1 0 1 1 1 0 GINS complex protein Sec16 PF12932.2 AJW71416.1 - 8.2 6.4 7.4 22 5.0 0.7 2.2 1 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region CDC37_N PF03234.9 AJW71416.1 - 8.6 6.6 16.4 1.1e+02 2.9 11.5 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Pcc1 PF09341.5 AJW71417.1 - 0.00017 21.5 0.1 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DpnD-PcfM PF14207.1 AJW71417.1 - 0.065 12.9 0.1 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 DpnD/PcfM-like protein GED PF02212.13 AJW71417.1 - 0.089 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Dynamin GTPase effector domain Aminotran_3 PF00202.16 AJW71417.1 - 0.12 11.1 0.1 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class-III Flagellin_IN PF07196.8 AJW71417.1 - 0.52 10.3 3.6 2 8.4 1.1 2.1 2 0 0 2 2 2 0 Flagellin hook IN motif Ribosomal_L37ae PF01780.14 AJW71418.1 - 3.7e-20 71.5 3.0 3.9e-20 71.5 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 AJW71418.1 - 0.00031 20.4 2.8 0.00056 19.6 2.0 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DZR PF12773.2 AJW71418.1 - 0.0026 17.5 0.4 0.0039 16.9 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.17 AJW71418.1 - 0.0045 16.6 1.5 0.0064 16.1 1.1 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 AJW71418.1 - 0.011 15.3 3.5 0.021 14.4 2.4 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DNA_ligase_ZBD PF03119.11 AJW71418.1 - 0.021 14.4 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain GCC2_GCC3 PF07699.8 AJW71418.1 - 0.036 13.6 1.0 0.048 13.2 0.7 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 Fusion_gly_K PF01621.12 AJW71418.1 - 0.042 12.8 0.0 0.047 12.7 0.0 1.0 1 0 0 1 1 1 0 Cell fusion glycoprotein K TF_Zn_Ribbon PF08271.7 AJW71418.1 - 0.051 12.8 2.8 0.1 11.9 1.9 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 AJW71418.1 - 0.055 13.4 1.6 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Rubredoxin PF00301.15 AJW71418.1 - 0.086 12.7 0.9 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin DNA_RNApol_7kD PF03604.8 AJW71418.1 - 0.087 12.3 0.7 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.1 AJW71418.1 - 0.094 12.4 1.1 0.17 11.6 0.8 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 AJW71418.1 - 0.11 12.0 1.8 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AJW71418.1 - 0.11 11.9 2.9 2 7.9 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 AJW71418.1 - 0.11 11.6 4.7 0.79 9.0 3.3 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Rep_fac-A_C PF08646.5 AJW71418.1 - 0.12 12.0 0.9 0.12 12.0 0.6 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain GFA PF04828.9 AJW71418.1 - 0.13 12.2 1.7 0.37 10.7 0.1 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ISL3 PF14690.1 AJW71418.1 - 0.2 11.7 3.5 0.27 11.2 0.1 2.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 NOB1_Zn_bind PF08772.6 AJW71418.1 - 0.24 11.2 2.8 0.4 10.5 1.5 1.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_S27 PF01599.14 AJW71418.1 - 0.27 11.0 2.2 0.43 10.4 1.5 1.4 1 1 0 1 1 1 0 Ribosomal protein S27a DUF1451 PF07295.6 AJW71418.1 - 0.35 10.6 1.6 1.9 8.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) zf-H2C2_2 PF13465.1 AJW71418.1 - 0.43 10.9 4.8 1.4 9.3 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Prim_Zn_Ribbon PF08273.7 AJW71418.1 - 0.48 10.5 4.1 1.3 9.2 2.9 1.7 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase RNA_POL_M_15KD PF02150.11 AJW71418.1 - 0.57 9.9 2.6 2 8.1 1.7 1.8 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit DUF2039 PF10217.4 AJW71418.1 - 0.84 9.6 4.4 1.8 8.6 3.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF2082 PF09855.4 AJW71418.1 - 1.1 9.1 4.3 3.6 7.5 0.0 2.3 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 AJW71418.1 - 1.4 8.6 5.4 6.6 6.5 3.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 zf-RanBP PF00641.13 AJW71418.1 - 2.9 7.0 6.4 1 8.5 0.7 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RNase_PH PF01138.16 AJW71419.1 - 6.8e-22 78.1 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AJW71419.1 - 1.4e-13 50.5 0.1 4.6e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 AJW71420.1 - 8.7e-35 119.9 0.0 1.2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AJW71420.1 - 2.2e-14 53.1 0.4 5.3e-14 51.8 0.3 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.24 AJW71421.1 - 5.8e-11 41.8 0.1 1.6e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AJW71421.1 - 0.0001 21.8 0.0 0.00026 20.5 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 AJW71421.1 - 0.0038 16.7 0.0 0.009 15.5 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 AJW71421.1 - 0.075 12.6 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 KH domain SBDS PF01172.13 AJW71422.1 - 8.1e-27 92.8 0.1 1.4e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 AJW71422.1 - 1.3e-21 76.6 0.3 1.9e-21 76.0 0.2 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain EFG_C PF00679.19 AJW71422.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G C-terminus RNA_pol_A_bac PF01000.21 AJW71423.1 - 2.3e-25 88.9 0.0 4.5e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AJW71423.1 - 1.3e-11 43.4 0.0 1.6e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L18e PF00828.14 AJW71424.1 - 6.4e-07 29.7 0.1 7.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L13 PF00572.13 AJW71425.1 - 1.9e-24 86.1 0.1 2.6e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 NCD1 PF04904.8 AJW71425.1 - 0.052 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Ribosomal_S9 PF00380.14 AJW71426.1 - 5.8e-34 116.9 0.5 6.7e-34 116.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NTP_transferase PF00483.18 AJW71427.1 - 2.1e-17 63.2 0.0 2.5e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AJW71427.1 - 5.3e-11 42.8 0.0 6.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 AJW71427.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 AJW71427.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Aconitase_C PF00694.14 AJW71428.1 - 2.2e-39 134.5 0.0 4e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 AJW71428.1 - 6.1e-05 22.5 0.1 0.0011 18.4 0.1 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus FAD_syn PF06574.7 AJW71428.1 - 0.00038 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 FAD synthetase Aconitase PF00330.15 AJW71429.1 - 3.3e-165 550.0 0.0 3.7e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AJW71430.1 - 3.2e-21 75.8 0.1 1.1e-19 70.8 0.1 2.2 1 1 1 2 2 2 2 Aconitase C-terminal domain Aconitase_2_N PF06434.8 AJW71430.1 - 0.0035 16.7 0.2 0.036 13.4 0.1 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Antitoxin-MazE PF04014.13 AJW71430.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Aconitase PF00330.15 AJW71431.1 - 2.7e-81 273.4 3.1 2.4e-56 191.1 0.4 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) eRF1_2 PF03464.10 AJW71433.1 - 3.9e-13 49.8 0.9 3.9e-13 49.8 0.6 2.2 2 1 1 3 3 3 1 eRF1 domain 2 DUF3834 PF12916.2 AJW71433.1 - 0.01 14.8 0.1 0.022 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) eRF1_3 PF03465.10 AJW71433.1 - 0.012 15.8 0.2 0.055 13.7 0.1 2.2 1 1 0 1 1 1 0 eRF1 domain 3 PG_binding_3 PF09374.5 AJW71433.1 - 0.092 12.7 0.3 23 5.0 0.0 2.8 2 1 0 2 2 2 0 Predicted Peptidoglycan domain DUF2115 PF09888.4 AJW71433.1 - 0.16 12.0 2.4 0.37 10.8 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) F420_ligase PF01996.11 AJW71434.1 - 3.5e-52 176.7 0.1 4e-52 176.5 0.1 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase DUF684 PF05075.9 AJW71435.1 - 0.0055 15.3 0.3 0.01 14.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF684) Nsp1_C PF05064.8 AJW71438.1 - 0.035 13.7 0.2 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Prefoldin PF02996.12 AJW71438.1 - 0.062 12.9 0.2 0.4 10.3 0.2 1.9 2 0 0 2 2 2 0 Prefoldin subunit DUF2854 PF11016.3 AJW71438.1 - 0.09 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) TPP_enzyme_C PF02775.16 AJW71439.1 - 1.4e-28 99.4 0.3 2e-28 98.8 0.2 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.3 AJW71439.1 - 1.1e-06 28.4 0.2 0.0003 20.6 0.2 3.0 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.14 AJW71440.1 - 5.4e-56 189.6 0.0 7.8e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 AJW71440.1 - 4.3e-29 101.6 0.0 8.1e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 AJW71440.1 - 1.3e-06 28.3 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.13 AJW71440.1 - 0.0007 19.1 0.3 0.0013 18.2 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain zf-ribbon_3 PF13248.1 AJW71441.1 - 0.023 13.8 5.7 0.37 10.0 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 AJW71441.1 - 0.2 11.3 0.2 0.2 11.3 0.1 2.5 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.1 AJW71441.1 - 0.67 9.5 12.0 2.1 7.9 8.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain DUF2387 PF09526.5 AJW71441.1 - 1.7 8.6 11.5 6.1 6.8 0.2 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) 2-Hacid_dh_C PF02826.14 AJW71442.1 - 1.2e-64 216.6 0.1 1.7e-64 216.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AJW71442.1 - 3.7e-32 110.5 0.0 4.2e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AJW71442.1 - 8.4e-09 35.4 0.2 1.8e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 AJW71442.1 - 9.1e-07 28.3 0.3 2.3e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 AJW71442.1 - 0.00056 20.2 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 AJW71442.1 - 0.0024 17.8 0.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain AdoHcyase_NAD PF00670.16 AJW71442.1 - 0.0044 16.8 0.1 0.0088 15.8 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ChuX_HutX PF06228.8 AJW71443.1 - 6.9e-11 41.6 0.0 8.4e-11 41.4 0.0 1.0 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX HemS PF05171.7 AJW71443.1 - 1.4e-08 34.5 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Haemin-degrading HemS.ChuX domain DAO PF01266.19 AJW71445.1 - 2.4e-41 141.8 0.0 3.5e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 AJW71445.1 - 6.8e-12 44.3 0.0 5.8e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 AJW71445.1 - 4.1e-06 26.8 0.4 0.00073 19.4 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AJW71445.1 - 5.2e-06 26.6 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AJW71445.1 - 6.2e-05 22.0 0.0 0.068 12.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 AJW71445.1 - 8.1e-05 22.9 2.7 0.11 12.9 0.1 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AJW71445.1 - 0.0017 18.3 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AJW71445.1 - 0.017 13.6 0.0 0.24 9.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 AJW71445.1 - 0.09 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 AJW71445.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 AJW71445.1 - 0.14 11.1 0.0 0.99 8.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 AJW71445.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Usp PF00582.21 AJW71446.1 - 0.00012 22.2 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family MAD PF05557.8 AJW71446.1 - 0.0038 15.4 0.1 0.0044 15.1 0.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Med10 PF09748.4 AJW71446.1 - 0.042 13.6 0.2 0.052 13.3 0.1 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Filament PF00038.16 AJW71448.1 - 0.016 14.7 9.6 0.018 14.5 6.6 1.0 1 0 0 1 1 1 0 Intermediate filament protein Nairo_nucleo PF02477.10 AJW71448.1 - 0.29 9.7 6.5 0.33 9.5 4.5 1.0 1 0 0 1 1 1 0 Nucleocapsid N protein GBP_C PF02841.9 AJW71448.1 - 0.73 8.9 15.9 0.85 8.7 11.0 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TMPIT PF07851.8 AJW71448.1 - 0.87 8.5 9.2 0.96 8.4 6.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein DivIVA PF05103.8 AJW71448.1 - 0.95 9.5 20.0 1.7 8.6 4.1 2.0 1 1 1 2 2 2 0 DivIVA protein Caudo_TAP PF02413.12 AJW71448.1 - 1.1 9.4 8.6 1.4 9.0 5.9 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF948 PF06103.6 AJW71448.1 - 1.8 8.5 5.4 1.9 8.3 3.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 AJW71448.1 - 1.9 8.5 9.9 3.4 7.7 6.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YgaB PF14182.1 AJW71448.1 - 2.7 8.2 6.9 1.3 9.3 2.6 2.1 1 1 1 2 2 2 0 YgaB-like protein DUF724 PF05266.9 AJW71448.1 - 3 7.4 14.0 3.7 7.1 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin PF02996.12 AJW71448.1 - 3 7.5 11.0 1.6 8.3 2.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit MDFI PF15316.1 AJW71448.1 - 3.9 7.4 10.8 4.7 7.1 7.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Translin PF01997.11 AJW71448.1 - 3.9 7.0 10.5 6.2 6.3 7.3 1.3 1 1 0 1 1 1 0 Translin family AAA_13 PF13166.1 AJW71448.1 - 4.1 5.7 14.5 4.5 5.6 10.0 1.1 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.9 AJW71448.1 - 4.8 6.8 10.6 7.8 6.1 2.8 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF444 PF04285.7 AJW71448.1 - 4.9 5.6 13.1 5.6 5.4 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) V_ATPase_I PF01496.14 AJW71448.1 - 5 4.8 9.4 5.6 4.6 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FTCD_C PF04961.7 AJW71448.1 - 6.3 6.1 10.8 7.2 5.9 7.0 1.3 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Effector_1 PF04518.7 AJW71448.1 - 6.9 5.5 10.8 7.4 5.4 7.5 1.1 1 0 0 1 1 1 0 Effector from type III secretion system ISG65-75 PF11727.3 AJW71448.1 - 7.7 5.4 18.1 12 4.8 12.6 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Prominin PF05478.6 AJW71448.1 - 9.7 3.5 8.7 4.7 4.6 3.3 1.6 1 1 1 2 2 2 0 Prominin TB PF00683.12 AJW71449.1 - 0.095 12.2 3.8 0.18 11.4 2.6 1.4 1 0 0 1 1 1 0 TB domain FlgD_ig PF13860.1 AJW71450.1 - 0.00015 21.4 0.1 0.00026 20.6 0.0 1.6 1 1 0 1 1 1 1 FlgD Ig-like domain Cupredoxin_1 PF13473.1 AJW71450.1 - 0.062 13.1 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain Iron_permease PF04120.7 AJW71450.1 - 0.42 10.1 1.9 0.72 9.4 0.1 2.0 2 0 0 2 2 2 0 Low affinity iron permease TruB_N PF01509.13 AJW71451.1 - 2.8e-24 85.9 2.9 2.4e-14 53.7 0.0 3.5 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AJW71451.1 - 5.3e-18 64.5 0.4 1e-17 63.6 0.3 1.5 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.7 AJW71451.1 - 9.3e-11 41.5 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 DKCLD (NUC011) domain Cytidylate_kin2 PF13189.1 AJW71452.1 - 5.5e-15 55.7 0.0 6.9e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 AJW71452.1 - 1.1e-14 54.8 0.0 1.7e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJW71452.1 - 3.4e-11 44.0 0.2 8e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 AJW71452.1 - 1.4e-07 31.5 0.1 3.3e-07 30.2 0.1 1.6 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 AJW71452.1 - 8.3e-06 25.7 0.0 0.00043 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 AJW71452.1 - 4.1e-05 23.5 0.1 0.00013 21.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA PF00004.24 AJW71452.1 - 0.00018 21.6 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 AJW71452.1 - 0.00026 21.0 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AJW71452.1 - 0.00092 18.4 0.0 0.0017 17.5 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 AJW71452.1 - 0.004 17.2 0.0 0.0091 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AJW71452.1 - 0.0069 16.2 0.1 0.016 15.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 AJW71452.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 AJW71452.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 AJW71452.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.7 AJW71452.1 - 0.017 14.1 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 AJW71452.1 - 0.027 13.5 0.3 0.072 12.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 AJW71452.1 - 0.04 13.9 0.0 0.063 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Guanylate_kin PF00625.16 AJW71452.1 - 0.041 13.3 0.2 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase DUF106 PF01956.11 AJW71453.1 - 2.1e-14 53.3 12.0 2.1e-13 50.1 3.6 2.0 2 0 0 2 2 2 2 Integral membrane protein DUF106 AAA_18 PF13238.1 AJW71454.1 - 9.8e-13 48.5 0.1 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AJW71454.1 - 9.2e-08 32.9 0.0 1.5e-07 32.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 AJW71454.1 - 2.1e-07 30.5 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KTI12 PF08433.5 AJW71454.1 - 8.9e-07 28.3 0.0 1.3e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 AJW71454.1 - 2.6e-05 24.2 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AJW71454.1 - 5e-05 23.0 1.8 0.00017 21.3 0.6 2.0 1 1 1 2 2 2 1 NTPase MMR_HSR1 PF01926.18 AJW71454.1 - 0.00022 21.1 0.1 0.00034 20.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 AJW71454.1 - 0.00023 21.0 0.0 0.0003 20.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AJW71454.1 - 0.00025 20.7 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AJW71454.1 - 0.00027 20.6 0.2 0.00061 19.5 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AJW71454.1 - 0.00047 20.0 0.1 0.001 18.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 AJW71454.1 - 0.00047 19.7 0.1 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 AJW71454.1 - 0.00065 19.8 0.1 0.0014 18.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AJW71454.1 - 0.00069 19.3 0.1 0.0011 18.6 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 AJW71454.1 - 0.0016 18.6 0.1 0.0047 17.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AJW71454.1 - 0.002 17.8 0.2 0.0051 16.5 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain Arch_ATPase PF01637.13 AJW71454.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase 6PF2K PF01591.13 AJW71454.1 - 0.0024 16.9 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.14 AJW71454.1 - 0.0028 17.1 0.5 0.0078 15.6 0.2 1.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 AJW71454.1 - 0.0033 16.5 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 AJW71454.1 - 0.0041 15.9 0.2 0.0071 15.1 0.1 1.3 1 0 0 1 1 1 1 ArgK protein Thymidylate_kin PF02223.12 AJW71454.1 - 0.0042 16.4 0.1 0.01 15.2 0.1 1.7 1 1 0 1 1 1 1 Thymidylate kinase ABC_tran PF00005.22 AJW71454.1 - 0.0046 17.2 0.4 0.0055 17.0 0.3 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 AJW71454.1 - 0.0054 16.7 0.0 0.0092 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 AJW71454.1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 AJW71454.1 - 0.0086 15.1 0.1 0.015 14.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 AJW71454.1 - 0.0087 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Miro PF08477.8 AJW71454.1 - 0.0087 16.5 0.3 0.02 15.4 0.2 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 AJW71454.1 - 0.014 14.6 1.3 0.041 13.1 0.3 2.1 2 1 0 2 2 2 0 ADP-ribosylation factor family KdpD PF02702.12 AJW71454.1 - 0.015 14.4 0.2 0.023 13.8 0.1 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain UPF0079 PF02367.12 AJW71454.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 AJW71454.1 - 0.031 13.7 1.0 0.12 11.8 0.1 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 AJW71454.1 - 0.033 13.6 0.2 0.075 12.4 0.1 1.7 1 1 1 2 2 2 0 AAA-like domain DUF2075 PF09848.4 AJW71454.1 - 0.039 12.9 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 AJW71454.1 - 0.039 12.8 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain APS_kinase PF01583.15 AJW71454.1 - 0.039 13.5 0.1 0.21 11.2 0.0 2.0 1 1 1 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.17 AJW71454.1 - 0.042 12.6 0.2 0.061 12.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.18 AJW71454.1 - 0.06 12.1 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family KAP_NTPase PF07693.9 AJW71454.1 - 0.066 12.1 0.1 0.13 11.2 0.0 1.4 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 AJW71454.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 AJW71454.1 - 0.074 12.6 0.9 0.23 11.0 0.6 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AJW71454.1 - 0.078 12.1 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pox_A32 PF04665.7 AJW71454.1 - 0.092 12.0 0.3 0.24 10.6 0.1 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein Guanylate_kin PF00625.16 AJW71454.1 - 0.15 11.4 0.8 0.27 10.6 0.1 1.8 2 1 0 2 2 2 0 Guanylate kinase SecY PF00344.15 AJW71455.1 - 9.1e-83 278.0 22.7 1.1e-82 277.7 15.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AJW71455.1 - 8.7e-11 41.1 1.6 3.1e-10 39.3 1.1 2.1 1 0 0 1 1 1 1 Plug domain of Sec61p Ribosomal_L18e PF00828.14 AJW71456.1 - 1.5e-20 73.9 0.6 2e-20 73.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L30 PF00327.15 AJW71457.1 - 8.6e-14 50.8 0.0 1.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.15 AJW71458.1 - 2.3e-19 68.9 0.3 3.6e-19 68.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AJW71458.1 - 3.8e-15 54.9 0.1 6.6e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DOMON PF03351.12 AJW71458.1 - 0.11 12.4 0.1 1.9 8.4 0.1 2.3 3 0 0 3 3 3 0 DOMON domain Ribosomal_L18p PF00861.17 AJW71459.1 - 5.4e-20 71.7 1.2 7.3e-20 71.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L18p/L5e family OTCace_N PF02729.16 AJW71460.1 - 4e-51 172.4 0.0 5.6e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 AJW71460.1 - 1.1e-46 158.5 0.0 2.1e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SRP54 PF00448.17 AJW71461.1 - 3.8e-69 232.0 0.9 6e-69 231.4 0.6 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 AJW71461.1 - 9.8e-11 41.6 7.9 2.3e-10 40.4 5.5 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 AJW71461.1 - 2e-07 30.8 0.1 3.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 AJW71461.1 - 1.9e-05 24.1 0.1 3.8e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Trypan_PARP PF05887.6 AJW71461.1 - 3.5e-05 23.6 119.4 4.4e-05 23.3 42.8 2.9 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) AAA_22 PF13401.1 AJW71461.1 - 4.1e-05 23.7 0.0 9.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AJW71461.1 - 9.6e-05 21.5 0.2 0.00017 20.7 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.14 AJW71461.1 - 0.00014 21.3 0.8 0.00046 19.6 0.6 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 AJW71461.1 - 0.00031 20.4 0.1 0.00058 19.5 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AJW71461.1 - 0.00043 20.3 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 AJW71461.1 - 0.0012 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AJW71461.1 - 0.0014 18.3 0.2 0.006 16.2 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 AJW71461.1 - 0.0016 17.4 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase KTI12 PF08433.5 AJW71461.1 - 0.0021 17.3 0.0 0.0047 16.1 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 AJW71461.1 - 0.0041 17.4 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.12 AJW71461.1 - 0.0064 15.8 0.3 0.022 14.1 0.0 2.1 3 0 0 3 3 2 1 Thymidylate kinase AAA PF00004.24 AJW71461.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) B12-binding PF02310.14 AJW71461.1 - 0.018 14.9 0.5 0.29 11.0 0.4 2.3 1 1 1 2 2 2 0 B12 binding domain AAA_28 PF13521.1 AJW71461.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AJW71461.1 - 0.029 14.0 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase TPP_enzyme_M PF00205.17 AJW71461.1 - 0.037 13.8 0.6 0.39 10.4 0.0 2.7 4 0 0 4 4 3 0 Thiamine pyrophosphate enzyme, central domain AAA_5 PF07728.9 AJW71461.1 - 0.042 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 AJW71461.1 - 0.043 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 AJW71461.1 - 0.046 12.5 0.1 0.17 10.6 0.1 1.9 1 1 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 AJW71461.1 - 0.058 13.1 0.4 1.4 8.6 0.1 2.3 1 1 1 2 2 2 0 NTPase DAP3 PF10236.4 AJW71461.1 - 0.063 12.2 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TK PF00265.13 AJW71461.1 - 0.072 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase PAT1 PF09770.4 AJW71461.1 - 4.1 5.5 11.9 5.2 5.1 8.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Prefoldin PF02996.12 AJW71462.1 - 5.5e-18 64.7 4.5 5.5e-17 61.5 3.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 AJW71462.1 - 0.003 17.2 6.0 0.0036 17.0 0.1 2.3 2 1 0 2 2 2 1 Prefoldin subunit DUF724 PF05266.9 AJW71462.1 - 0.16 11.5 4.8 0.068 12.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 AJW71462.1 - 0.19 11.5 5.6 0.52 10.1 0.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 AJW71462.1 - 0.24 11.1 4.6 1.5 8.5 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sipho_Gp157 PF05565.6 AJW71462.1 - 0.34 10.4 3.8 0.21 11.1 0.8 1.8 2 0 0 2 2 2 0 Siphovirus Gp157 FliD_C PF07195.7 AJW71462.1 - 0.34 10.1 5.8 0.57 9.4 4.0 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus PilO PF04350.8 AJW71462.1 - 1.7 8.5 7.2 0.46 10.3 2.0 1.9 2 0 0 2 2 2 0 Pilus assembly protein, PilO Sod_Fe_C PF02777.13 AJW71463.1 - 1.1e-43 147.3 0.2 1.8e-43 146.6 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AJW71463.1 - 3.9e-29 100.7 0.4 7.5e-29 99.8 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_S8 PF00082.17 AJW71464.1 - 2.6e-61 207.2 0.6 3.7e-61 206.7 0.4 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 AJW71464.1 - 1.2e-11 44.1 0.0 5.2e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 PA domain PEPCK_ATP PF01293.15 AJW71465.1 - 8.8e-216 716.8 0.0 1e-215 716.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 AJW71465.1 - 0.15 11.6 0.1 0.4 10.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32e PF01655.13 AJW71466.1 - 4.9e-37 126.3 0.3 6.1e-37 126.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L19e PF01280.15 AJW71467.1 - 4.3e-43 146.6 8.7 5.1e-43 146.3 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e Fe_hyd_SSU PF02256.12 AJW71467.1 - 0.0035 17.3 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit DNA_binding_1 PF01035.15 AJW71468.1 - 1.4e-28 98.4 0.0 1.6e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain IceA2 PF05862.6 AJW71468.1 - 0.32 10.7 2.4 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein tRNA_deacylase PF04414.7 AJW71469.1 - 1.1e-62 210.9 0.0 1.4e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase MbeD_MobD PF04899.7 AJW71469.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 MbeD/MobD like SecE PF00584.15 AJW71470.1 - 0.00051 19.5 0.0 0.00058 19.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Spt5-NGN PF03439.8 AJW71471.1 - 2.6e-20 71.9 0.0 4.2e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 AJW71471.1 - 6.8e-07 28.7 0.3 1.5e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 KOW motif NusG PF02357.14 AJW71471.1 - 0.01 16.0 0.0 0.044 14.0 0.0 2.0 1 1 0 1 1 1 0 Transcription termination factor nusG Ribosomal_L11_N PF03946.9 AJW71472.1 - 2.9e-24 84.2 0.6 5.5e-24 83.3 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AJW71472.1 - 6.1e-19 67.9 1.7 1e-18 67.2 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Bac_Ubq_Cox PF01654.12 AJW71473.1 - 0.0026 16.2 0.3 0.0032 15.9 0.2 1.0 1 0 0 1 1 1 1 Bacterial Cytochrome Ubiquinol Oxidase Yip1 PF04893.12 AJW71473.1 - 0.039 13.4 0.7 0.057 12.9 0.5 1.2 1 0 0 1 1 1 0 Yip1 domain DUF1469 PF07332.6 AJW71473.1 - 0.072 12.8 0.6 8.4 6.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF308 PF03729.8 AJW71473.1 - 0.14 12.2 4.3 3.1 7.8 0.1 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) HATPase_c PF02518.21 AJW71474.1 - 1.4e-22 79.5 0.5 1.4e-21 76.2 0.1 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW71474.1 - 8.4e-11 41.7 0.2 4.2e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 AJW71474.1 - 4.2e-08 32.9 1.1 3.1e-07 30.1 0.1 2.3 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.20 AJW71474.1 - 1.8e-07 31.2 3.6 2.3e-07 30.8 0.0 2.7 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.1 AJW71474.1 - 1.7e-05 24.4 0.3 5.2e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 GHKL domain DUF4600 PF15372.1 AJW71474.1 - 0.077 13.2 5.9 0.15 12.3 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Phosphonate-bd PF12974.2 AJW71475.1 - 1.4e-45 155.6 0.0 1.6e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein tRNA_anti-like PF12869.2 AJW71475.1 - 0.12 11.8 0.4 0.33 10.4 0.1 1.8 2 0 0 2 2 2 0 tRNA_anti-like Response_reg PF00072.19 AJW71476.1 - 1.1e-22 80.1 0.2 1.2e-22 80.0 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 AJW71476.1 - 0.00053 19.8 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain potato_inhibit PF00280.13 AJW71476.1 - 0.043 13.9 0.2 7.5 6.7 0.0 2.3 1 1 1 2 2 2 0 Potato inhibitor I family Saccharop_dh_N PF04455.7 AJW71476.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region TPP_enzyme_N PF02776.13 AJW71477.1 - 2.5e-61 206.1 0.0 2.2e-60 203.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AJW71477.1 - 2.5e-37 127.8 0.0 7.3e-37 126.2 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AJW71477.1 - 4.7e-31 107.3 0.1 1.1e-30 106.1 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 AJW71477.1 - 0.002 17.7 0.0 0.0063 16.0 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit AsnC_trans_reg PF01037.16 AJW71480.1 - 1.5e-16 59.8 0.1 2.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 AJW71480.1 - 8.7e-08 31.4 0.2 1.4e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AJW71480.1 - 0.00048 19.6 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain B-block_TFIIIC PF04182.7 AJW71480.1 - 0.00051 19.8 0.1 0.00081 19.1 0.1 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.17 AJW71480.1 - 0.0024 17.5 0.1 0.004 16.8 0.1 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 AJW71480.1 - 0.0045 16.6 0.1 0.0087 15.7 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_psq PF05225.11 AJW71480.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain MarR_2 PF12802.2 AJW71480.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 MarR family Ribosomal_S25 PF03297.10 AJW71480.1 - 0.018 15.0 0.7 0.031 14.3 0.1 1.6 2 0 0 2 2 2 0 S25 ribosomal protein HTH_11 PF08279.7 AJW71480.1 - 0.024 14.2 0.4 0.068 12.8 0.1 1.8 2 0 0 2 2 2 0 HTH domain HTH_27 PF13463.1 AJW71480.1 - 0.079 13.2 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Ribosomal_L1 PF00687.16 AJW71481.1 - 8.9e-46 155.9 2.3 1.1e-45 155.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L10 PF00466.15 AJW71482.1 - 3.2e-17 62.2 1.1 7.6e-17 61.0 0.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AJW71482.1 - 0.033 14.5 1.7 0.047 14.0 0.4 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein HPHLAWLY PF14925.1 AJW71482.1 - 0.039 11.9 1.3 0.43 8.5 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function Amidase_3 PF01520.13 AJW71482.1 - 0.093 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF4407 PF14362.1 AJW71483.1 - 0.0074 15.2 2.6 0.011 14.7 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Cache_3 PF14827.1 AJW71483.1 - 0.009 15.9 0.0 1.6 8.6 0.0 2.8 2 1 0 2 2 2 2 Sensory domain of two-component sensor kinase DUF4064 PF13273.1 AJW71483.1 - 0.38 10.8 5.3 0.95 9.6 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) HATPase_c PF02518.21 AJW71484.1 - 3.1e-18 65.5 0.1 5.5e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 AJW71484.1 - 2.8e-10 39.7 0.7 4.2e-10 39.2 0.1 1.6 2 0 0 2 2 2 1 GHKL domain HisKA PF00512.20 AJW71484.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HMA PF00403.21 AJW71484.1 - 0.023 14.8 1.6 0.19 11.8 0.2 3.0 3 1 1 4 4 4 0 Heavy-metal-associated domain RNA_pol_A_CTD PF03118.10 AJW71484.1 - 0.097 12.1 1.1 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain FixG_C PF11614.3 AJW71484.1 - 0.18 11.9 3.7 0.15 12.1 1.4 1.7 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Response_reg PF00072.19 AJW71485.1 - 6.4e-24 84.1 0.0 7.1e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Peptidase_S48 PF03574.10 AJW71486.1 - 0.086 12.8 0.1 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S48 DUF4369 PF14289.1 AJW71488.1 - 0.04 13.9 0.1 0.08 12.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) DUF3823 PF12866.2 AJW71488.1 - 0.064 12.7 0.1 0.21 11.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3823) DUF432 PF04254.8 AJW71489.1 - 2.7e-25 88.6 0.0 4.4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF432) MS_channel PF00924.13 AJW71490.1 - 8.4e-47 159.1 4.6 1.2e-46 158.6 3.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel Ribosomal_S21 PF01165.15 AJW71490.1 - 0.012 15.0 0.0 0.042 13.2 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S21 FecCD PF01032.13 AJW71490.1 - 0.025 13.4 9.5 0.015 14.1 4.9 1.7 1 1 0 1 1 1 0 FecCD transport family NnrS PF05940.7 AJW71490.1 - 0.057 12.3 4.6 0.072 11.9 3.2 1.1 1 0 0 1 1 1 0 NnrS protein End_beta_propel PF12217.3 AJW71490.1 - 0.083 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase HATPase_c PF02518.21 AJW71491.1 - 1.7e-22 79.2 0.3 4.7e-22 77.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 AJW71491.1 - 2.2e-13 50.6 0.0 3.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 AJW71491.1 - 2.1e-08 34.0 0.5 5.4e-08 32.7 0.3 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW71491.1 - 2.4e-06 27.1 2.5 1.6e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 GHKL domain GAF_3 PF13492.1 AJW71491.1 - 1.8e-05 24.8 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 AJW71491.1 - 0.00084 19.0 1.2 0.0016 18.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW71491.1 - 0.036 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain GAF_2 PF13185.1 AJW71491.1 - 0.048 14.1 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 GAF domain Mitofilin PF09731.4 AJW71491.1 - 0.075 11.6 11.3 0.1 11.2 7.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DM13 PF10517.4 AJW71492.1 - 1.7e-27 95.9 0.0 2.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 VCX_VCY PF15231.1 AJW71492.1 - 8.7 6.7 10.9 32 4.8 7.6 1.8 1 1 0 1 1 1 0 Variable charge X/Y family HATPase_c PF02518.21 AJW71493.1 - 5.1e-20 71.2 0.2 8.6e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 AJW71493.1 - 1.6e-07 30.9 0.1 1.6e-07 30.9 0.1 1.8 2 1 1 3 3 3 1 GHKL domain HATPase_c_3 PF13589.1 AJW71493.1 - 3.1e-05 23.6 0.0 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP-synt_ab_C PF00306.22 AJW71493.1 - 2.1 8.8 4.7 13 6.2 3.2 2.2 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain Glyoxalase_2 PF12681.2 AJW71494.1 - 1.7e-15 57.5 0.0 2e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AJW71494.1 - 2e-15 56.9 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 AJW71494.1 - 5.6e-09 35.9 0.0 3.8e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AJW71494.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 2 0 0 2 2 2 0 Glyoxalase-like domain Med29 PF11568.3 AJW71495.1 - 0.093 12.7 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 29 Cupin_2 PF07883.6 AJW71496.1 - 7.1e-10 38.2 0.6 1.1e-09 37.6 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 AJW71496.1 - 0.00057 19.2 0.1 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 AJW71496.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.14 AJW71496.1 - 0.0087 15.7 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 AJW71496.1 - 0.013 15.0 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase ARD PF03079.9 AJW71496.1 - 0.056 13.3 0.1 0.15 11.9 0.0 1.7 1 1 1 2 2 2 0 ARD/ARD' family Cupin_6 PF12852.2 AJW71496.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Cupin zf-CDGSH PF09360.5 AJW71497.1 - 9.4e-12 44.5 0.2 1.4e-11 44.0 0.2 1.3 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type CFC PF09443.5 AJW71497.1 - 2.4 7.8 5.3 1.3 8.7 2.3 1.6 1 1 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Rhodanese PF00581.15 AJW71499.1 - 5.3e-26 91.1 0.0 2e-12 47.4 0.0 2.8 3 0 0 3 3 3 2 Rhodanese-like domain Lactamase_B PF00753.22 AJW71499.1 - 3.3e-25 88.8 2.4 5.7e-25 88.1 1.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AJW71499.1 - 0.007 15.9 0.7 0.019 14.5 0.5 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.1 AJW71499.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Rhodanese PF00581.15 AJW71500.1 - 3.1e-13 50.0 0.0 3.6e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF4179 PF13786.1 AJW71501.1 - 0.05 13.8 0.4 0.05 13.8 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) HU-DNA_bdg PF14848.1 AJW71501.1 - 0.18 11.5 8.5 1.2 8.9 0.2 2.5 1 1 1 2 2 2 0 DNA-binding domain DUF778 PF05608.7 AJW71501.1 - 0.61 10.0 9.1 7.5 6.4 6.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF778) TryThrA_C PF12319.3 AJW71501.1 - 0.67 9.1 20.3 1.4 8.0 14.1 1.5 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Tape_meas_lam_C PF09718.5 AJW71501.1 - 0.86 9.5 5.1 7 6.6 0.1 3.2 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF1789 PF08748.6 AJW71501.1 - 4.5 7.3 13.6 24 5.0 9.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1789) V-ATPase_G PF03179.10 AJW71501.1 - 7.5 6.9 28.8 1.1e+02 3.1 14.9 3.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit KfrA_N PF11740.3 AJW71501.1 - 7.5 7.0 11.1 4.3 7.7 1.2 2.8 1 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term Sec20 PF03908.8 AJW71501.1 - 8.8 6.1 8.6 5.3 6.8 0.2 3.4 1 1 4 5 5 5 0 Sec20 DUF4220 PF13968.1 AJW71501.1 - 9.5 5.2 8.3 4.6 6.2 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) Phage_int_SAM_4 PF13495.1 AJW71502.1 - 0.085 13.1 0.7 0.14 12.4 0.5 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DICT PF10069.4 AJW71504.1 - 0.0027 17.2 0.0 0.0045 16.5 0.0 1.3 1 1 0 1 1 1 1 Sensory domain found in DIguanylate Cyclases & Two-component systems Sec34 PF04136.10 AJW71504.1 - 0.2 11.3 1.9 0.14 11.9 0.3 1.4 2 0 0 2 2 2 0 Sec34-like family Epimerase PF01370.16 AJW71506.1 - 9.8e-25 87.3 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AJW71506.1 - 4.3e-15 56.1 0.0 5.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 AJW71506.1 - 7.4e-15 54.5 0.0 2.8e-07 29.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 AJW71506.1 - 1.7e-14 53.2 0.0 7.9e-14 51.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJW71506.1 - 7.1e-12 44.8 0.0 3e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AJW71506.1 - 1.4e-07 30.7 0.0 1.4e-05 24.1 0.0 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 AJW71506.1 - 2.6e-05 23.6 0.1 7e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 AJW71506.1 - 0.0049 16.8 0.0 0.04 13.8 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 AJW71506.1 - 0.13 12.6 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF389 PF04087.9 AJW71507.1 - 1.6e-30 105.8 15.8 1.6e-30 105.8 10.9 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF389) DUF1461 PF07314.6 AJW71507.1 - 1.9 8.2 10.2 1.7 8.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Usp PF00582.21 AJW71508.1 - 5.8e-31 107.5 0.0 6.5e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Arg_tRNA_synt_N PF03485.11 AJW71508.1 - 0.044 14.3 0.9 0.49 10.9 0.6 2.2 1 1 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF424 PF04242.8 AJW71508.1 - 0.12 12.4 0.7 0.2 11.7 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF424) VanZ PF04892.7 AJW71509.1 - 0.005 16.7 0.7 0.0091 15.9 0.5 1.6 1 1 0 1 1 1 1 VanZ like family Transport_MerF PF11431.3 AJW71509.1 - 0.072 12.7 4.0 0.63 9.7 0.3 2.8 2 0 0 2 2 2 0 Membrane transport protein MerF DUF3796 PF12676.2 AJW71509.1 - 0.75 10.0 0.1 0.75 10.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) DUF3392 PF11872.3 AJW71509.1 - 9.7 6.2 9.3 1.5 8.7 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) DUF3179 PF11376.3 AJW71510.1 - 3.2e-97 324.8 0.0 3.7e-97 324.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3179) DUF4097 PF13349.1 AJW71510.1 - 0.061 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PBP_like_2 PF12849.2 AJW71511.1 - 4e-50 170.8 2.8 5.1e-50 170.5 2.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.20 AJW71511.1 - 1.9e-14 54.1 0.4 1.9e-14 54.1 0.3 1.7 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.2 AJW71511.1 - 4.7e-07 28.9 0.0 2e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 PBP superfamily domain PhoU PF01895.14 AJW71512.1 - 3.6e-18 65.7 15.0 8.7e-15 54.9 0.7 2.9 3 0 0 3 3 3 2 PhoU domain Antitoxin-MazE PF04014.13 AJW71512.1 - 0.00034 20.2 0.0 0.00091 18.9 0.0 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE G-alpha PF00503.15 AJW71512.1 - 0.76 8.3 8.8 5 5.7 6.1 2.0 1 1 0 1 1 1 0 G-protein alpha subunit BPD_transp_1 PF00528.17 AJW71513.1 - 3.7e-18 65.6 17.2 3.7e-18 65.6 11.9 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2583 PF10762.4 AJW71513.1 - 5.6 7.1 6.3 14 5.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2583) BPD_transp_1 PF00528.17 AJW71514.1 - 1.4e-18 67.0 23.5 1.9e-18 66.6 10.6 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.22 AJW71515.1 - 7e-30 104.1 0.0 1e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJW71515.1 - 3.1e-15 56.8 0.0 6e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 AJW71515.1 - 1.8e-10 40.4 0.1 4.2e-10 39.2 0.1 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AJW71515.1 - 2.4e-06 26.8 1.6 0.016 14.2 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AJW71515.1 - 1.7e-05 24.9 0.0 7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 AJW71515.1 - 0.0001 22.6 1.5 0.00035 20.9 1.1 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AJW71515.1 - 0.00046 19.4 0.0 0.00088 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 AJW71515.1 - 0.0018 18.0 0.4 0.07 12.8 0.3 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 AJW71515.1 - 0.0019 17.7 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 AJW71515.1 - 0.0043 16.5 0.3 0.12 11.8 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_16 PF13191.1 AJW71515.1 - 0.0044 17.0 0.1 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 AJW71515.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 AJW71515.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 AJW71515.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AJW71515.1 - 0.019 15.8 0.2 0.049 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AJW71515.1 - 0.024 14.0 0.0 0.058 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 AJW71515.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 AJW71515.1 - 0.047 13.3 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 AJW71515.1 - 0.051 13.7 3.1 0.49 10.6 0.1 3.0 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AJW71515.1 - 0.053 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 AJW71515.1 - 0.057 13.3 0.6 0.21 11.4 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AJW71515.1 - 0.059 13.1 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 AJW71515.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 AJW71515.1 - 0.083 11.9 1.3 0.26 10.3 0.1 2.2 2 1 1 3 3 3 0 KaiC G-alpha PF00503.15 AJW71515.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.1 AJW71515.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoU PF01895.14 AJW71516.1 - 1.1e-20 73.8 8.1 4e-10 40.0 1.5 2.4 3 0 0 3 3 3 2 PhoU domain DUF2116 PF09889.4 AJW71517.1 - 0.00046 19.9 0.7 0.00074 19.2 0.5 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1064 PF06356.6 AJW71517.1 - 0.0012 18.8 0.4 0.0014 18.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1064) zf-ribbon_3 PF13248.1 AJW71517.1 - 0.0061 15.7 0.4 0.01 15.0 0.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain FIBP PF05427.6 AJW71517.1 - 0.018 14.2 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) zinc_ribbon_2 PF13240.1 AJW71517.1 - 0.026 13.9 1.1 0.026 13.9 0.8 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Ecl1 PF12855.2 AJW71517.1 - 0.028 13.7 2.5 0.046 13.0 1.7 1.3 1 0 0 1 1 1 0 Life-span regulatory factor DUF2113 PF09886.4 AJW71517.1 - 0.044 12.9 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Prok-RING_1 PF14446.1 AJW71517.1 - 0.07 12.8 1.6 0.1 12.3 1.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RHH_1 PF01402.16 AJW71517.1 - 0.076 12.9 0.3 0.19 11.6 0.2 1.8 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family AMP-binding_C_2 PF14535.1 AJW71517.1 - 0.12 12.4 0.4 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF329 PF03884.9 AJW71517.1 - 0.22 11.1 1.4 0.35 10.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF329) Ribosomal_L24e PF01246.15 AJW71517.1 - 0.34 10.7 2.6 4.8 7.1 1.8 2.2 1 1 0 1 1 1 0 Ribosomal protein L24e zf-BED PF02892.10 AJW71517.1 - 0.85 9.4 7.5 1.9 8.3 5.2 1.9 1 1 0 1 1 1 0 BED zinc finger zf-FCS PF06467.9 AJW71517.1 - 9.4 5.9 8.7 1.6e+02 2.0 6.0 2.4 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Response_reg PF00072.19 AJW71518.1 - 1.1e-18 67.2 1.3 1.4e-18 66.9 0.9 1.1 1 0 0 1 1 1 1 Response regulator receiver domain PHA-1 PF06542.6 AJW71519.1 - 0.081 11.6 0.4 0.095 11.4 0.3 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 Hexapep PF00132.19 AJW71520.1 - 9.9e-19 65.9 21.0 1.4e-08 33.8 1.8 3.4 1 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJW71520.1 - 3e-05 23.4 27.7 0.0074 15.8 5.0 5.3 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF1069 PF06370.6 AJW71520.1 - 0.3 10.4 2.1 0.37 10.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Tup_N PF08581.5 AJW71521.1 - 0.16 12.2 2.2 0.15 12.2 1.2 1.3 1 1 0 1 1 1 0 Tup N-terminal P-II PF00543.17 AJW71522.1 - 1.2e-21 77.0 1.0 1.4e-21 76.8 0.7 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Sod_Fe_C PF02777.13 AJW71523.1 - 1.2e-43 147.2 0.8 1.8e-43 146.7 0.2 1.4 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AJW71523.1 - 8.1e-28 96.5 0.4 1.4e-27 95.7 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Usp PF00582.21 AJW71524.1 - 1.2e-18 67.6 0.0 1.5e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF1744 PF08490.7 AJW71524.1 - 0.071 11.6 0.7 0.088 11.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Usp PF00582.21 AJW71525.1 - 1.6e-09 38.1 0.0 1.7e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family XendoU PF09412.5 AJW71525.1 - 0.032 13.2 2.3 0.036 13.1 1.6 1.1 1 0 0 1 1 1 0 Endoribonuclease XendoU Methyltransf_24 PF13578.1 AJW71525.1 - 0.099 13.4 0.2 0.16 12.8 0.1 1.3 1 1 0 1 1 1 0 Methyltransferase domain DUF3334 PF11813.3 AJW71525.1 - 0.11 12.0 2.3 0.11 11.9 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3334) N6-adenineMlase PF10237.4 AJW71525.1 - 0.12 12.0 2.1 0.16 11.6 1.4 1.3 1 1 0 1 1 1 0 Probable N6-adenine methyltransferase DUF2465 PF10239.4 AJW71525.1 - 0.14 11.2 2.1 0.18 10.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) AAA_22 PF13401.1 AJW71525.1 - 0.15 12.2 0.3 0.22 11.6 0.2 1.3 1 1 0 1 1 1 0 AAA domain DOPA_dioxygen PF08883.6 AJW71525.1 - 0.18 11.8 1.4 0.51 10.4 0.6 2.0 1 1 1 2 2 2 0 Dopa 4,5-dioxygenase family TM_helix PF05552.7 AJW71526.1 - 2.3e-13 49.6 6.6 6.1e-07 29.0 0.3 3.2 2 0 0 2 2 2 2 Conserved TM helix MS_channel PF00924.13 AJW71526.1 - 1.1e-07 31.4 9.4 1.1e-07 31.4 6.5 2.3 2 0 0 2 2 2 1 Mechanosensitive ion channel TM1506 PF08973.5 AJW71526.1 - 0.027 14.0 0.4 0.056 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1893) TMEM237 PF15383.1 AJW71526.1 - 0.082 12.0 6.1 0.35 9.9 0.4 2.4 2 1 1 3 3 3 0 Transmembrane protein 237 ATPase_gene1 PF09527.5 AJW71526.1 - 0.097 12.4 0.5 0.097 12.4 0.4 3.8 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) NPCC PF08058.6 AJW71526.1 - 0.37 10.6 5.5 0.68 9.7 0.4 2.6 1 1 0 2 2 2 0 Nuclear pore complex component DUF3353 PF11833.3 AJW71526.1 - 1.6 8.1 7.9 3 7.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) UPF0154 PF03672.8 AJW71526.1 - 1.8 8.2 6.2 3.3 7.3 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Colicin_V PF02674.11 AJW71526.1 - 2.3 8.0 27.0 0.2 11.5 6.2 3.4 2 2 1 3 3 3 0 Colicin V production protein PDEase_I PF00233.14 AJW71528.1 - 0.026 14.2 1.9 0.053 13.2 1.3 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Acetyltransf_7 PF13508.1 AJW71528.1 - 0.031 14.4 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AJW71528.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Guanylate_cyc PF00211.15 AJW71529.1 - 1.1e-20 73.7 0.1 1.7e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MS_channel PF00924.13 AJW71530.1 - 2.4e-26 92.3 9.1 7.4e-26 90.7 6.3 1.8 1 1 0 1 1 1 1 Mechanosensitive ion channel Arc_PepC PF06819.6 AJW71531.1 - 0.57 10.1 2.4 0.59 10.0 1.7 1.0 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain TFIIB PF00382.14 AJW71532.1 - 9e-25 86.2 0.1 6e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AJW71532.1 - 5.8e-06 25.5 1.7 1.2e-05 24.4 1.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AJW71532.1 - 0.00065 19.2 0.1 0.002 17.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_10 PF04967.7 AJW71532.1 - 0.047 13.2 0.4 21 4.7 0.0 3.6 4 0 0 4 4 4 0 HTH DNA binding domain Orexin_rec2 PF03827.8 AJW71532.1 - 2.2 8.4 5.1 16 5.6 0.3 3.1 2 1 0 2 2 2 0 Orexin receptor type 2 HSP20 PF00011.16 AJW71533.1 - 7.9e-11 41.7 1.0 1.2e-09 37.9 0.7 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PIH1 PF08190.7 AJW71533.1 - 1.8e-05 24.3 0.1 2.1e-05 24.1 0.1 1.0 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 AJW71533.1 - 0.026 15.0 0.3 0.043 14.3 0.2 1.4 1 1 0 1 1 1 0 CS domain zf-C3HC4_3 PF13920.1 AJW71534.1 - 0.0031 17.1 1.5 0.0031 17.1 1.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 AJW71534.1 - 0.011 15.6 6.7 0.014 15.3 4.6 1.2 1 0 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 AJW71534.1 - 0.02 14.7 8.3 0.053 13.3 5.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 AJW71534.1 - 0.27 10.9 5.5 0.93 9.1 2.9 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-HC5HC2H_2 PF13832.1 AJW71534.1 - 0.28 11.2 8.4 0.37 10.8 5.8 1.3 1 1 0 1 1 1 0 PHD-zinc-finger like domain zinc_ribbon_2 PF13240.1 AJW71534.1 - 0.81 9.2 9.2 2.2 7.8 3.2 3.0 2 1 1 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 AJW71534.1 - 1.2 9.0 7.6 2 8.2 3.8 2.0 1 1 1 2 2 2 0 zinc-ribbons DUF2039 PF10217.4 AJW71534.1 - 2.4 8.2 7.0 2.2 8.3 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) DnaJ_CXXCXGXG PF00684.14 AJW71534.1 - 2.8 8.0 9.1 0.54 10.3 1.3 2.0 1 1 1 2 2 2 0 DnaJ central domain Usp PF00582.21 AJW71535.1 - 2e-23 83.1 0.0 2.5e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family DUF4415 PF14384.1 AJW71536.1 - 0.014 15.5 0.2 0.021 14.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) RHH_3 PF12651.2 AJW71536.1 - 0.052 13.2 0.2 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain DoxX PF07681.7 AJW71537.1 - 1e-10 41.8 1.8 1e-10 41.8 1.3 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.8 AJW71537.1 - 2.2e-06 27.4 1.0 3.9e-06 26.6 0.7 1.3 1 0 0 1 1 1 1 TQO small subunit DoxD DoxX_2 PF13564.1 AJW71537.1 - 0.0027 17.6 4.8 0.0052 16.7 3.3 1.6 1 1 0 1 1 1 1 DoxX-like family C1_1 PF00130.17 AJW71538.1 - 0.061 13.0 3.0 0.12 12.1 2.1 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Usp PF00582.21 AJW71539.1 - 3.5e-28 98.5 1.0 4.1e-28 98.3 0.7 1.1 1 0 0 1 1 1 1 Universal stress protein family Pro_dh PF01619.13 AJW71539.1 - 0.024 13.6 0.6 0.029 13.3 0.4 1.1 1 0 0 1 1 1 0 Proline dehydrogenase Lipoprotein_6 PF01441.14 AJW71539.1 - 0.036 13.8 2.6 0.078 12.8 1.6 1.7 1 1 0 1 1 1 0 Lipoprotein Sec23_trunk PF04811.10 AJW71539.1 - 0.055 12.8 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain TatD_DNase PF01026.16 AJW71539.1 - 0.1 11.7 0.5 0.4 9.8 0.1 1.7 1 1 1 2 2 2 0 TatD related DNase Fcf1 PF04900.7 AJW71539.1 - 0.1 12.6 0.3 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Fcf1 FliT PF05400.8 AJW71539.1 - 0.11 12.9 0.3 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 Flagellar protein FliT HTH_40 PF14493.1 AJW71539.1 - 0.13 12.5 1.0 1.8 8.8 0.7 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S30AE PF02482.14 AJW71539.1 - 0.27 11.6 2.4 0.62 10.5 0.4 2.0 1 1 1 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Spore_YabQ PF09578.5 AJW71541.1 - 0.39 10.7 8.1 0.067 13.1 2.3 2.2 1 1 2 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) Na_Ca_ex PF01699.19 AJW71542.1 - 1.5e-55 186.6 38.7 5.8e-29 100.4 10.4 2.3 2 1 0 2 2 2 2 Sodium/calcium exchanger protein TMEM61 PF15105.1 AJW71542.1 - 0.021 14.3 0.1 1.6 8.1 0.1 2.4 2 0 0 2 2 2 0 TMEM61 protein family PepSY_TM_2 PF13703.1 AJW71542.1 - 0.021 14.9 4.9 0.69 10.1 0.1 3.9 3 2 0 3 3 3 0 PepSY-associated TM helix Zn-ribbon_8 PF09723.5 AJW71543.1 - 0.00024 20.9 1.9 0.00032 20.5 1.3 1.2 1 0 0 1 1 1 1 Zinc ribbon domain RNA_POL_M_15KD PF02150.11 AJW71543.1 - 0.0018 17.9 0.4 0.0026 17.4 0.3 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit zf-C2HC5 PF06221.8 AJW71543.1 - 0.003 17.2 0.5 0.0034 17.1 0.3 1.1 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type RRN7 PF11781.3 AJW71543.1 - 0.0031 16.9 0.8 2.1 7.9 0.1 2.2 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Prok-RING_1 PF14446.1 AJW71543.1 - 0.0068 16.1 1.2 0.0095 15.6 0.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DUF1451 PF07295.6 AJW71543.1 - 0.0081 15.9 0.7 0.0085 15.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1451) RecR PF02132.10 AJW71543.1 - 0.0092 15.4 3.6 0.61 9.5 0.2 2.1 1 1 1 2 2 2 2 RecR protein DZR PF12773.2 AJW71543.1 - 0.0095 15.7 2.5 0.014 15.2 1.7 1.3 1 1 0 1 1 1 1 Double zinc ribbon TF_Zn_Ribbon PF08271.7 AJW71543.1 - 0.0099 15.1 2.2 0.3 10.4 0.1 2.2 1 1 1 2 2 2 1 TFIIB zinc-binding HypA PF01155.14 AJW71543.1 - 0.013 15.2 0.5 0.014 15.1 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 AJW71543.1 - 0.014 14.6 0.7 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.16 AJW71543.1 - 0.033 14.0 0.9 0.036 13.9 0.6 1.1 1 0 0 1 1 1 0 IBR domain zf-C2H2_6 PF13912.1 AJW71543.1 - 0.034 14.0 3.4 1.7 8.6 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger UPF0547 PF10571.4 AJW71543.1 - 0.036 13.7 1.9 4.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ribosomal_L32p PF01783.18 AJW71543.1 - 0.038 14.1 2.2 0.6 10.3 0.1 2.1 1 1 2 3 3 3 0 Ribosomal L32p protein family RNHCP PF12647.2 AJW71543.1 - 0.038 13.8 0.2 0.039 13.7 0.2 1.1 1 0 0 1 1 1 0 RNHCP domain Mu-like_Com PF10122.4 AJW71543.1 - 0.048 12.7 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage protein Com A2L_zn_ribbon PF08792.5 AJW71543.1 - 0.077 12.4 1.3 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Rtf2 PF04641.7 AJW71543.1 - 0.1 11.8 0.2 0.087 12.0 0.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger C1_1 PF00130.17 AJW71543.1 - 0.12 12.0 0.8 0.15 11.8 0.5 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GATA PF00320.22 AJW71543.1 - 0.13 11.6 1.3 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 GATA zinc finger zf-NADH-PPase PF09297.6 AJW71543.1 - 0.13 11.8 2.5 3.1 7.4 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-MYND PF01753.13 AJW71543.1 - 0.14 12.0 2.5 0.24 11.3 1.8 1.3 1 1 0 1 1 1 0 MYND finger Rubredoxin PF00301.15 AJW71543.1 - 0.14 12.0 2.8 5.1 7.0 1.9 2.3 1 1 0 1 1 1 0 Rubredoxin TFIIS_C PF01096.13 AJW71543.1 - 0.16 11.6 1.6 9.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2321 PF10083.4 AJW71543.1 - 0.17 11.3 1.4 0.27 10.7 1.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-BED PF02892.10 AJW71543.1 - 0.19 11.4 0.7 0.27 11.0 0.5 1.3 1 0 0 1 1 1 0 BED zinc finger zinc_ribbon_5 PF13719.1 AJW71543.1 - 0.23 11.0 6.2 1.7 8.3 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AJW71543.1 - 0.24 11.2 3.1 3.9 7.3 0.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJW71543.1 - 0.26 11.0 6.0 2.2 8.0 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.9 AJW71543.1 - 0.28 10.8 2.8 1.1 8.9 0.2 2.1 1 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2 PF00096.21 AJW71543.1 - 0.35 11.2 2.0 3.2 8.2 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type FYVE PF01363.16 AJW71543.1 - 0.65 9.9 3.9 44 4.0 0.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-trcl PF13451.1 AJW71543.1 - 0.9 9.2 3.2 28 4.4 2.2 2.1 1 1 0 1 1 1 0 Probable zinc-binding domain Auto_anti-p27 PF06677.7 AJW71543.1 - 1.2 8.9 3.4 10 6.0 0.1 2.1 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-AN1 PF01428.11 AJW71543.1 - 2.2 8.2 4.8 6.1 6.8 0.3 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger DUF3797 PF12677.2 AJW71543.1 - 3.9 7.1 5.5 15 5.3 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zinc_ribbon_2 PF13240.1 AJW71543.1 - 5.4 6.6 7.5 1e+02 2.5 5.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain HTH_6 PF01418.12 AJW71544.1 - 0.047 13.4 0.6 2.1 8.1 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family DUF2682 PF10909.3 AJW71544.1 - 0.078 13.2 0.1 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) KAR PF15222.1 AJW71544.1 - 0.12 12.4 0.1 0.43 10.7 0.0 1.7 2 0 0 2 2 2 0 Kidney androgen-regulated Cor1 PF04803.7 AJW71545.1 - 0.0073 16.0 2.0 0.0083 15.8 0.8 1.5 1 1 1 2 2 2 1 Cor1/Xlr/Xmr conserved region Retrotrans_gag PF03732.12 AJW71545.1 - 0.13 12.3 0.7 0.48 10.5 0.4 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein DUF1059 PF06348.6 AJW71546.1 - 6e-07 29.1 0.0 7.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) DUF4451 PF14616.1 AJW71546.1 - 0.032 13.9 0.1 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) AsnC_trans_reg PF01037.16 AJW71547.1 - 2.3e-19 68.8 0.5 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 AsnC family GYD PF08734.6 AJW71547.1 - 0.001 18.7 0.0 0.39 10.4 0.0 2.2 2 0 0 2 2 2 2 GYD domain DUF1479 PF07350.7 AJW71547.1 - 0.025 13.0 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) HMA PF00403.21 AJW71547.1 - 0.074 13.2 1.9 0.81 9.8 0.2 2.8 2 1 1 3 3 3 0 Heavy-metal-associated domain DUF2209 PF09974.4 AJW71547.1 - 0.081 13.0 0.2 0.31 11.1 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) DUF2129 PF09902.4 AJW71547.1 - 0.095 12.5 0.0 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) GCC2_GCC3 PF07699.8 AJW71548.1 - 0.052 13.1 1.0 0.068 12.7 0.7 1.2 1 0 0 1 1 1 0 GCC2 and GCC3 DUF2318 PF10080.4 AJW71548.1 - 0.25 11.1 1.9 0.24 11.1 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Pr_beta_C PF12465.3 AJW71549.1 - 0.39 10.0 1.9 7.6 5.8 0.1 2.1 2 0 0 2 2 2 0 Proteasome beta subunits C terminal UPF0126 PF03458.8 AJW71550.1 - 1.9e-42 142.7 30.0 2.9e-23 81.2 5.0 2.4 3 0 0 3 3 3 2 UPF0126 domain PEN-2 PF10251.4 AJW71550.1 - 0.74 10.0 4.6 1.4 9.1 0.8 2.5 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Ribosomal_60s PF00428.14 AJW71551.1 - 2.4e-13 50.2 19.8 2.9e-13 50.0 13.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 AJW71551.1 - 0.058 13.3 5.5 0.51 10.2 2.2 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain HATPase_c PF02518.21 AJW71553.1 - 1.7e-22 79.2 0.0 4.5e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW71553.1 - 1.3e-07 31.4 0.3 2.8e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW71553.1 - 6.5e-07 28.9 0.1 3.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 AJW71553.1 - 3.4e-06 26.7 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AJW71553.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain TAFII55_N PF04658.8 AJW71553.1 - 0.023 14.1 1.3 4.2 6.8 0.1 2.5 2 0 0 2 2 2 0 TAFII55 protein conserved region DUF1053 PF06327.9 AJW71553.1 - 0.12 12.7 2.3 0.2 11.9 0.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) tRNA-synt_2c PF01411.14 AJW71554.1 - 7.4e-80 268.7 0.1 7.4e-80 268.7 0.1 1.8 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 AJW71554.1 - 7.7e-15 54.5 1.0 7.7e-15 54.5 0.7 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AJW71554.1 - 1e-05 25.0 3.7 2.9e-05 23.6 2.6 1.8 1 0 0 1 1 1 1 DHHA1 domain YolD PF08863.5 AJW71554.1 - 0.00063 19.5 0.1 0.016 15.0 0.1 2.8 2 0 0 2 2 2 1 YolD-like protein tRNA-synt_1 PF00133.17 AJW71555.1 - 1.4e-60 204.9 1.1 1.5e-59 201.6 0.8 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AJW71555.1 - 9.9e-25 87.0 0.5 3e-12 45.8 0.0 3.3 2 1 1 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AJW71555.1 - 6.6e-23 81.1 0.3 1.4e-22 80.1 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AJW71555.1 - 8.2e-12 44.8 4.1 1.5e-07 30.8 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 AJW71555.1 - 9.3e-08 31.5 0.2 4.9e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 DUF3652 PF12372.3 AJW71555.1 - 0.23 11.1 0.0 0.52 9.9 0.0 1.5 1 0 0 1 1 1 0 Huntingtin protein region FoP_duplication PF13865.1 AJW71556.1 - 6.1 7.3 9.9 6.9 7.1 6.9 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 UVR PF02151.14 AJW71558.1 - 0.0033 16.8 0.1 0.0092 15.4 0.0 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif Peripla_BP_2 PF01497.13 AJW71558.1 - 0.0094 15.0 0.1 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein DUF3422 PF11902.3 AJW71558.1 - 0.039 12.8 0.1 0.06 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Matrilin_ccoil PF10393.4 AJW71558.1 - 0.067 12.5 0.2 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CorA PF01544.13 AJW71558.1 - 0.088 11.8 0.5 0.12 11.3 0.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4320 PF14208.1 AJW71558.1 - 0.17 11.8 0.7 1.8 8.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) Val_tRNA-synt_C PF10458.4 AJW71558.1 - 0.44 10.6 2.6 0.42 10.7 0.5 2.0 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm HSCB_C PF07743.8 AJW71558.1 - 0.67 10.4 4.4 4.7 7.7 1.8 2.5 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain zinc_ribbon_4 PF13717.1 AJW71559.1 - 0.0014 18.2 2.0 0.64 9.7 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJW71559.1 - 0.0021 17.6 2.7 0.8 9.3 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AJW71559.1 - 0.049 13.1 3.6 2.8 7.4 2.5 2.2 1 1 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 AJW71559.1 - 0.059 13.1 1.5 0.079 12.7 1.0 1.2 1 0 0 1 1 1 0 Double zinc ribbon CbiN PF02553.10 AJW71559.1 - 0.061 13.3 0.1 0.061 13.3 0.1 2.0 1 1 1 2 2 2 0 Cobalt transport protein component CbiN IncA PF04156.9 AJW71559.1 - 0.078 12.5 2.5 0.094 12.3 1.8 1.1 1 0 0 1 1 1 0 IncA protein zf-H2C2_2 PF13465.1 AJW71559.1 - 0.11 12.7 2.7 0.67 10.3 0.5 2.1 2 0 0 2 2 2 0 Zinc-finger double domain PolC_DP2 PF03833.8 AJW71559.1 - 0.13 9.9 0.3 0.14 9.8 0.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-NADH-PPase PF09297.6 AJW71559.1 - 0.17 11.3 4.5 0.97 9.0 0.2 2.1 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ninjurin PF04923.7 AJW71559.1 - 0.19 11.5 2.1 0.24 11.1 1.5 1.3 1 1 0 1 1 1 0 Ninjurin CitMHS PF03600.11 AJW71559.1 - 0.26 9.8 7.7 0.29 9.6 5.3 1.0 1 0 0 1 1 1 0 Citrate transporter YdfA_immunity PF12127.3 AJW71559.1 - 0.32 9.8 5.4 0.36 9.6 3.7 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial TF_Zn_Ribbon PF08271.7 AJW71559.1 - 0.39 10.0 5.2 4.8 6.5 0.5 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DUF3487 PF11990.3 AJW71559.1 - 0.44 9.9 4.8 0.48 9.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) P12 PF12669.2 AJW71559.1 - 0.46 10.7 9.0 3.1 8.0 6.2 2.0 1 1 0 1 1 1 0 Virus attachment protein p12 family zf-C2H2 PF00096.21 AJW71559.1 - 1.1 9.7 5.5 2.3 8.7 0.4 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.1 AJW71559.1 - 1.3 8.3 6.2 6.1 6.2 4.3 1.9 1 1 0 1 1 1 0 zinc-ribbon domain DUF2207 PF09972.4 AJW71559.1 - 1.3 7.5 4.2 1.3 7.4 2.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-AN1 PF01428.11 AJW71559.1 - 1.3 8.9 4.6 13 5.7 3.8 1.9 1 1 1 2 2 2 0 AN1-like Zinc finger O-antigen_lig PF13425.1 AJW71559.1 - 1.4 8.8 6.7 1.6 8.7 4.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein EcsB PF05975.7 AJW71559.1 - 2 6.7 9.0 2.2 6.6 6.3 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB zinc_ribbon_2 PF13240.1 AJW71559.1 - 2.2 7.8 6.5 5.5 6.6 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon domain VirB3 PF05101.8 AJW71559.1 - 2.3 8.2 7.0 2.9 7.9 4.9 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF3099 PF11298.3 AJW71559.1 - 2.4 7.9 9.4 2.8 7.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) zf-C2HC_2 PF13913.1 AJW71559.1 - 3.2 7.5 6.0 1.8 8.3 0.5 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF4191 PF13829.1 AJW71559.1 - 4.5 6.3 6.0 4.5 6.3 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tic20 PF09685.5 AJW71559.1 - 4.8 7.2 11.1 5.7 6.9 7.7 1.1 1 0 0 1 1 1 0 Tic20-like protein DUF2244 PF10003.4 AJW71559.1 - 5.8 6.2 8.0 6.4 6.1 5.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Usp PF00582.21 AJW71561.1 - 2.7e-31 108.6 0.0 3.1e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Pro_Al_protease PF02983.9 AJW71561.1 - 0.00088 19.1 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-lytic protease prodomain CamS PF07537.6 AJW71561.1 - 0.02 13.9 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor ATP-grasp_5 PF13549.1 AJW71561.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain Usp PF00582.21 AJW71562.1 - 1.1e-26 93.7 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family dTMP_synthase PF02593.9 AJW71562.1 - 0.088 12.1 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase HTH_3 PF01381.17 AJW71562.1 - 0.09 12.6 0.2 0.28 11.0 0.1 1.9 2 1 0 2 2 2 0 Helix-turn-helix LEA_2 PF03168.8 AJW71564.1 - 0.00094 19.5 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF4307 PF14155.1 AJW71564.1 - 0.0065 16.2 0.4 0.013 15.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) TarH PF02203.10 AJW71564.1 - 0.19 11.5 0.4 0.33 10.7 0.3 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue NVEALA PF14055.1 AJW71564.1 - 0.2 11.3 0.7 0.45 10.2 0.5 1.6 1 0 0 1 1 1 0 NVEALA protein Response_reg PF00072.19 AJW71565.1 - 1.8e-22 79.4 0.2 2.2e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain PE-PPE PF08237.6 AJW71565.1 - 0.033 13.6 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain CoA_binding PF02629.14 AJW71565.1 - 0.036 14.5 0.1 0.056 13.9 0.1 1.4 1 0 0 1 1 1 0 CoA binding domain Rad50_zn_hook PF04423.9 AJW71566.1 - 0.16 11.4 0.4 0.16 11.4 0.3 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.1 AJW71566.1 - 0.3 10.3 3.4 9.9 5.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-IS66 PF13005.2 AJW71566.1 - 0.81 9.7 7.5 3.8 7.5 0.4 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DZR PF12773.2 AJW71566.1 - 2 8.2 7.0 4.2 7.2 4.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-ISL3 PF14690.1 AJW71566.1 - 4.6 7.3 8.1 2.3 8.3 0.5 2.7 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RHH_3 PF12651.2 AJW71568.1 - 0.0065 16.1 1.0 0.57 9.9 0.1 2.1 1 1 1 2 2 2 2 Ribbon-helix-helix domain zinc-ribbons_6 PF07191.7 AJW71569.1 - 0.19 11.5 0.9 0.41 10.4 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbons HNH_5 PF14279.1 AJW71569.1 - 0.2 11.6 1.6 0.41 10.6 1.1 1.9 1 1 0 1 1 1 0 HNH endonuclease PhnA_Zn_Ribbon PF08274.7 AJW71569.1 - 0.66 9.8 2.6 2.2 8.1 1.8 1.7 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-AD PF07776.10 AJW71569.1 - 2.3 8.3 4.6 5.2 7.1 0.2 2.4 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) Gin PF10764.4 AJW71569.1 - 2.6 7.8 4.7 10 5.8 3.2 2.0 1 1 0 1 1 1 0 Inhibitor of sigma-G Gin FYVE_2 PF02318.11 AJW71569.1 - 7.2 6.5 6.4 4.9 7.0 0.8 2.1 1 1 0 2 2 2 0 FYVE-type zinc finger DUF948 PF06103.6 AJW71570.1 - 0.044 13.6 2.0 0.079 12.8 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nitroreductase PF00881.19 AJW71571.1 - 1.2e-38 132.5 0.0 2.1e-38 131.7 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.1 AJW71571.1 - 0.042 13.0 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative TM nitroreductase Geminin PF07412.7 AJW71571.1 - 0.051 13.2 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Geminin PhnH PF05845.7 AJW71571.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) Trp_halogenase PF04820.9 AJW71572.1 - 2.7e-05 23.0 0.0 9.1e-05 21.2 0.0 1.7 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_2 PF03446.10 AJW71572.1 - 0.00039 20.2 0.1 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 AJW71572.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 AJW71572.1 - 0.044 13.7 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 AJW71572.1 - 0.078 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AJW71572.1 - 0.13 11.6 0.0 0.65 9.3 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CxxCxxCC PF03692.10 AJW71573.1 - 2.1e-08 34.5 0.7 7.2e-08 32.7 0.5 1.9 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Ribosomal_S7 PF00177.16 AJW71575.1 - 2.2e-36 124.6 0.5 3.3e-36 124.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.20 AJW71576.1 - 1.3e-38 131.1 0.4 1.6e-38 130.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KH_2 PF07650.12 AJW71577.1 - 1.1e-19 69.7 4.7 2.4e-13 49.4 0.3 2.1 1 1 1 2 2 2 2 KH domain KH_4 PF13083.1 AJW71577.1 - 8.5e-12 44.5 0.8 1.7e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 AJW71577.1 - 1.5e-08 34.3 3.6 3.5e-08 33.1 0.3 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.24 AJW71577.1 - 2.2e-06 27.1 0.8 0.0022 17.6 0.0 2.6 2 0 0 2 2 2 2 KH domain Ribosomal_L7Ae PF01248.21 AJW71578.1 - 3.6e-14 52.0 0.2 4.4e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pox_VLTF3 PF04947.9 AJW71578.1 - 0.057 12.9 0.5 0.069 12.6 0.4 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like A2M_N PF01835.14 AJW71579.1 - 0.0059 16.8 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 2 MG2 domain LSM PF01423.17 AJW71580.1 - 2.5e-18 65.3 1.7 3e-18 65.1 1.2 1.0 1 0 0 1 1 1 1 LSM domain RNA_pol_Rpb1_5 PF04998.12 AJW71581.1 - 1.5e-84 283.5 2.5 3.3e-84 282.4 1.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AJW71581.1 - 1.2e-82 277.9 3.4 1.1e-81 274.7 0.2 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AJW71581.1 - 1.2e-69 233.4 0.0 3e-69 232.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AJW71581.1 - 3.7e-33 114.5 0.0 9.3e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AJW71581.1 - 2.3e-24 85.1 1.2 4.8e-23 80.9 0.2 3.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Lumazine_bd PF12870.2 AJW71581.1 - 0.031 14.3 0.5 0.094 12.7 0.4 1.8 1 0 0 1 1 1 0 Lumazine-binding domain Spore_III_AF PF09581.5 AJW71581.1 - 0.04 13.7 5.7 0.037 13.8 2.3 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) UPF0547 PF10571.4 AJW71581.1 - 0.11 12.1 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 RNA_pol_Rpb2_6 PF00562.23 AJW71582.1 - 1.9e-122 408.7 0.0 2.9e-122 408.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AJW71582.1 - 3.6e-55 186.0 0.0 5.3e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AJW71582.1 - 1e-29 102.5 0.0 2.4e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 AJW71582.1 - 7.9e-27 92.8 0.1 1.9e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 AJW71582.1 - 1.5e-24 86.4 0.0 4.1e-24 85.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 AJW71582.1 - 7e-14 51.3 0.1 2.2e-13 49.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 AJW71582.1 - 9.6e-12 44.6 0.5 2e-11 43.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 AJW71582.1 - 0.056 13.2 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37e PF01907.14 AJW71582.1 - 0.19 11.5 0.7 0.47 10.2 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e OrfB_Zn_ribbon PF07282.6 AJW71582.1 - 0.23 11.1 0.9 0.75 9.4 0.6 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RNA_pol_Rpb5_C PF01191.14 AJW71583.1 - 4.6e-29 99.8 0.1 5.3e-29 99.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain A2M_N PF01835.14 AJW71584.1 - 7.2e-06 26.1 0.1 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 MG2 domain Big_3_4 PF13754.1 AJW71584.1 - 0.018 15.3 1.9 0.69 10.2 0.1 3.2 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) Cbl_N3 PF02762.9 AJW71584.1 - 0.15 11.6 0.0 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Big_2 PF02368.13 AJW71584.1 - 5.4 6.9 8.6 12 5.8 4.4 2.5 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 2) A2M_N PF01835.14 AJW71585.1 - 0.00021 21.4 0.6 0.34 11.1 0.1 2.4 2 0 0 2 2 2 2 MG2 domain Gmad2 PF10648.4 AJW71585.1 - 0.0036 17.4 2.5 0.26 11.4 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin-like domain of bacterial spore germination FlgD_ig PF13860.1 AJW71585.1 - 0.0055 16.4 4.7 0.059 13.1 0.2 2.8 2 1 0 2 2 2 1 FlgD Ig-like domain DUF4369 PF14289.1 AJW71585.1 - 0.084 12.8 3.7 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) CBM_6 PF03422.10 AJW71585.1 - 0.75 9.9 5.2 1.7 8.7 1.2 2.2 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) TrbC PF04956.8 AJW71585.1 - 7.5 6.6 10.5 0.46 10.5 1.7 2.3 2 0 0 2 2 2 0 TrbC/VIRB2 family He_PIG PF05345.7 AJW71586.1 - 0.15 12.1 6.0 0.27 11.2 0.0 3.2 3 0 0 3 3 3 0 Putative Ig domain Saf-Nte_pilin PF09460.5 AJW71586.1 - 2.1 8.1 6.9 4.1 7.1 2.7 2.5 2 1 1 3 3 3 0 Saf-pilin pilus formation protein Big_3_4 PF13754.1 AJW71586.1 - 6.4 7.1 10.0 4.1 7.8 0.5 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Aminotran_5 PF00266.14 AJW71588.1 - 1.4e-89 300.4 0.0 1.8e-89 300.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AJW71588.1 - 7.5e-07 28.5 0.0 8.7e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AJW71588.1 - 4.3e-06 25.9 0.0 9.5e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AJW71588.1 - 0.0001 20.7 0.0 0.0002 19.7 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AJW71588.1 - 0.00014 20.9 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AJW71588.1 - 0.01 14.3 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.16 AJW71588.1 - 0.037 12.8 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class-III QueC PF06508.8 AJW71589.1 - 1.3e-07 31.1 0.0 7.9e-07 28.5 0.0 2.1 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 AJW71589.1 - 1.8e-07 30.3 0.0 2.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.15 AJW71589.1 - 5.4e-07 29.2 0.0 5.2e-06 26.0 0.1 2.2 2 1 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.11 AJW71589.1 - 1.7e-06 26.8 0.1 4.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 AJW71589.1 - 3.5e-06 26.7 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 AJW71589.1 - 7.2e-05 22.3 0.0 0.00019 20.9 0.0 1.8 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) DUF111 PF01969.12 AJW71590.1 - 5.2e-111 371.1 0.2 5.9e-111 370.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 Ldh_1_N PF00056.18 AJW71591.1 - 1.8e-37 128.2 0.5 4e-37 127.1 0.3 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AJW71591.1 - 1.1e-30 106.6 0.0 1.7e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AIRC PF00731.15 AJW71592.1 - 1.4e-20 73.1 2.8 2.5e-20 72.2 1.9 1.4 1 0 0 1 1 1 1 AIR carboxylase NAD_kinase PF01513.16 AJW71592.1 - 0.0019 17.0 0.1 0.0034 16.2 0.1 1.6 1 1 0 1 1 1 1 ATP-NAD kinase Hpr_kinase_N PF02603.11 AJW71592.1 - 0.0091 15.6 2.6 0.42 10.2 0.4 2.3 2 0 0 2 2 2 2 HPr Serine kinase N terminus Radical_SAM PF04055.16 AJW71593.1 - 2.5e-12 47.3 0.0 4.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.14 AJW71593.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Trypan_PARP PF05887.6 AJW71595.1 - 5e-09 36.1 36.4 1.1e-08 35.0 25.2 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RseC_MucC PF04246.7 AJW71595.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC NESP55 PF06390.7 AJW71595.1 - 1.2 8.4 11.2 1.8 7.9 7.7 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Neisseria_TspB PF05616.8 AJW71595.1 - 2.5 6.3 18.1 3.5 5.8 12.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein A2M_N PF01835.14 AJW71596.1 - 0.0021 18.3 0.0 0.041 14.1 0.0 3.3 2 0 0 2 2 2 1 MG2 domain Zip PF02535.17 AJW71597.1 - 4.6e-07 29.1 15.2 4.6e-07 29.1 10.5 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter Cu-oxidase_3 PF07732.10 AJW71598.1 - 1.5e-23 82.7 6.5 2.4e-20 72.4 0.5 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AJW71598.1 - 1.2e-18 67.0 8.8 3.1e-08 33.2 0.3 3.3 3 0 0 3 3 3 3 Multicopper oxidase EMP24_GP25L PF01105.19 AJW71599.1 - 0.035 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 AJW71599.1 - 7.4 6.1 9.2 0.87 9.1 0.3 2.2 2 0 0 2 2 2 0 IncA protein HTH_20 PF12840.2 AJW71600.1 - 0.056 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HsdM_N PF12161.3 AJW71600.1 - 0.057 13.8 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain HTH_45 PF14947.1 AJW71600.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DUF4423 PF14394.1 AJW71600.1 - 0.12 11.8 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Ribosomal_S13 PF00416.17 AJW71601.1 - 2.2e-28 98.8 0.0 2.7e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 AJW71601.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif S4 PF01479.20 AJW71602.1 - 8.8e-10 37.8 1.3 2.3e-09 36.5 0.0 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.14 AJW71602.1 - 4.4e-05 23.7 1.2 6.8e-05 23.1 0.7 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SIS PF01380.17 AJW71603.1 - 2.2e-50 169.6 2.9 4.2e-28 97.5 0.9 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 AJW71603.1 - 1.1e-24 86.8 0.0 2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AJW71603.1 - 2.9e-20 72.2 0.1 3.6e-16 58.8 0.0 2.7 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 AJW71603.1 - 1.2e-19 70.2 0.1 3.6e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS_2 PF13580.1 AJW71603.1 - 2.4e-10 40.2 3.5 6.2e-05 22.7 0.5 4.1 3 1 1 4 4 4 2 SIS domain GATase_4 PF13230.1 AJW71603.1 - 2.8e-09 36.0 0.2 4.8e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DBI_PRT PF02277.12 AJW71604.1 - 7.9e-25 87.6 0.1 1.1e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyltransferase Lactamase_B PF00753.22 AJW71605.1 - 1e-26 93.8 0.5 1.3e-26 93.4 0.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AJW71605.1 - 6.2e-06 25.8 0.6 1.2e-05 24.9 0.4 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain KAR PF15222.1 AJW71605.1 - 0.011 15.8 0.0 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 Kidney androgen-regulated YjeF_N PF03853.10 AJW71606.1 - 1.2e-47 161.6 0.0 1.5e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF1126 PF06565.7 AJW71607.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1126) fn3 PF00041.16 AJW71608.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Translin PF01997.11 AJW71609.1 - 1.8e-31 109.3 2.4 2.8e-31 108.7 1.7 1.3 1 0 0 1 1 1 1 Translin family Ribonuc_red_lgN PF00317.16 AJW71609.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain RNA_pol_N PF01194.12 AJW71610.1 - 5.8e-29 99.9 0.5 7.2e-29 99.5 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit PhaP_Bmeg PF09602.5 AJW71610.1 - 0.034 13.9 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Chordopox_RPO7 PF05864.7 AJW71610.1 - 0.23 11.5 1.6 0.61 10.2 1.1 1.7 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Enolase_C PF00113.17 AJW71611.1 - 3.7e-55 186.9 0.4 5.9e-55 186.3 0.0 1.4 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AJW71611.1 - 2.7e-26 92.0 0.0 6.1e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain CW_binding_2 PF04122.7 AJW71611.1 - 0.00057 20.0 1.8 0.0018 18.4 0.4 2.3 3 0 0 3 3 3 1 Putative cell wall binding repeat 2 Ribosomal_S2 PF00318.15 AJW71612.1 - 6.3e-35 120.3 1.2 9.8e-17 60.8 0.6 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 AP_endonuc_2 PF01261.19 AJW71612.1 - 0.037 13.3 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel GHMP_kinases_N PF00288.21 AJW71613.1 - 1.7e-21 76.0 0.5 3.3e-21 75.1 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AJW71613.1 - 9.2e-14 51.4 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 AJW71613.1 - 0.058 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature AA_kinase PF00696.23 AJW71614.1 - 1.6e-25 90.1 0.0 1.8e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF1967 PF09269.6 AJW71614.1 - 0.0089 15.6 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) NUDIX PF00293.23 AJW71615.1 - 3.3e-12 46.2 0.0 4.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain polyprenyl_synt PF00348.12 AJW71616.1 - 1.2e-70 237.3 0.0 1.4e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 AJW71616.1 - 0.037 13.2 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain tRNA-synt_1c PF00749.16 AJW71617.1 - 1.1e-74 250.9 0.0 1.5e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AJW71617.1 - 1.6e-25 89.8 2.7 4.3e-25 88.3 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain FAA_hydrolase PF01557.13 AJW71618.1 - 2.4e-67 226.6 0.0 3e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 AJW71618.1 - 0.0019 18.5 0.0 0.0058 16.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) Acetyltransf_1 PF00583.19 AJW71619.1 - 7.6e-07 29.0 0.0 1.9e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJW71619.1 - 0.0003 20.8 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 AJW71619.1 - 0.078 13.0 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Rieske PF00355.21 AJW71620.1 - 1.3e-18 66.3 0.0 1.5e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AJW71620.1 - 9.6e-10 38.1 0.0 1.1e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0147 PF03685.8 AJW71621.1 - 1.7e-32 111.1 2.6 1.9e-32 110.9 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) DUF1840 PF08895.6 AJW71621.1 - 0.015 15.2 0.5 0.021 14.8 0.2 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) UvrB PF12344.3 AJW71621.1 - 0.021 14.3 1.4 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B DUF3461 PF11944.3 AJW71621.1 - 0.036 13.9 0.1 0.27 11.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) UPF0253 PF06786.7 AJW71621.1 - 0.042 13.9 0.1 5.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0253) Vip3A_N PF12495.3 AJW71621.1 - 0.077 12.6 0.4 0.082 12.5 0.2 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal LepA_C PF06421.7 AJW71621.1 - 0.11 12.4 0.1 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus Methyltransf_25 PF13649.1 AJW71622.1 - 1.2e-05 25.6 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW71622.1 - 2.6e-05 23.8 2.0 4.2e-05 23.1 1.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJW71622.1 - 0.00028 21.3 0.0 0.00063 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 AJW71622.1 - 0.00029 20.2 1.2 0.016 14.5 0.4 2.5 2 1 0 2 2 2 1 Histone methylation protein DOT1 CUB PF00431.15 AJW71622.1 - 0.0078 16.2 0.5 2.7 8.1 0.0 2.3 2 0 0 2 2 2 2 CUB domain Methyltransf_18 PF12847.2 AJW71622.1 - 0.029 14.9 0.1 0.057 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 AJW71622.1 - 0.053 12.6 0.1 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 AJW71622.1 - 0.078 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.9 AJW71622.1 - 0.11 11.8 0.1 0.41 9.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain CorA PF01544.13 AJW71624.1 - 5.4e-69 232.4 1.3 6.2e-69 232.2 0.9 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1351 PF07083.6 AJW71624.1 - 0.0014 18.2 2.1 0.0019 17.8 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1351) Anti-adapt_IraP PF10796.4 AJW71624.1 - 0.082 13.2 0.2 7.6 6.9 0.0 3.0 2 1 1 3 3 3 0 Sigma-S stabilisation anti-adaptor protein DUF4319 PF14203.1 AJW71624.1 - 0.094 12.2 1.5 2.4 7.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) DUF1664 PF07889.7 AJW71624.1 - 0.12 12.2 0.8 0.3 10.8 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Snf7 PF03357.16 AJW71624.1 - 0.21 10.9 1.0 0.78 9.0 0.7 1.8 1 1 0 1 1 1 0 Snf7 DUF2746 PF10874.3 AJW71624.1 - 7.3 6.8 13.3 4.5 7.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) DUF4023 PF13215.1 AJW71625.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4023) Transaldolase PF00923.14 AJW71626.1 - 2.6e-61 207.2 0.0 1.5e-60 204.8 0.0 2.0 1 1 0 1 1 1 1 Transaldolase Transket_pyr PF02779.19 AJW71627.1 - 9e-32 109.9 0.0 1.4e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AJW71627.1 - 7.7e-29 100.1 0.0 1.4e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 AJW71628.1 - 9.5e-64 215.3 0.6 3.6e-62 210.1 0.4 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Ribul_P_3_epim PF00834.14 AJW71628.1 - 1.9e-51 174.0 0.3 3e-51 173.4 0.2 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DXP_synthase_N PF13292.1 AJW71628.1 - 9.8e-06 24.6 0.1 0.00019 20.4 0.1 2.6 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 AJW71628.1 - 1.5e-05 24.6 0.1 3.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 AJW71628.1 - 1.5e-05 23.8 0.0 2.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component XFP_N PF09364.5 AJW71628.1 - 0.00024 19.8 0.8 0.0024 16.5 0.1 2.3 2 0 0 2 2 2 1 XFP N-terminal domain DUF393 PF04134.7 AJW71629.1 - 0.0081 17.2 0.0 0.011 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Peptidase_M17 PF00883.16 AJW71630.1 - 3.2e-114 381.0 0.5 4.3e-114 380.5 0.4 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 AJW71630.1 - 4.6e-18 65.1 0.1 1.3e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain zf-Di19 PF05605.7 AJW71631.1 - 0.03 14.4 0.0 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ABC_tran PF00005.22 AJW71632.1 - 1.1e-39 135.9 1.4 1.5e-18 67.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 AJW71632.1 - 1.2e-10 40.8 1.4 1.2e-10 40.8 1.0 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 AJW71632.1 - 3e-09 36.0 12.1 7.7e-09 34.7 4.4 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.14 AJW71632.1 - 6.5e-09 35.3 6.3 0.00024 20.3 0.3 2.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4_6 PF12837.2 AJW71632.1 - 1.5e-08 34.0 16.5 1.6e-07 30.9 3.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain AAA_21 PF13304.1 AJW71632.1 - 3.9e-07 30.3 11.8 0.28 11.0 0.0 4.9 3 2 1 4 4 4 3 AAA domain Fer4_7 PF12838.2 AJW71632.1 - 4.5e-06 26.9 11.8 2.9e-05 24.3 8.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJW71632.1 - 4.9e-06 26.1 12.4 1e-05 25.1 2.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 AJW71632.1 - 1.3e-05 24.9 13.2 2.3e-05 24.1 9.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain DUF258 PF03193.11 AJW71632.1 - 4.7e-05 22.6 0.4 0.014 14.5 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Fer4_10 PF13237.1 AJW71632.1 - 9.8e-05 22.0 25.9 0.00071 19.3 2.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_15 PF13175.1 AJW71632.1 - 0.00022 20.3 2.5 2.3 7.1 0.0 4.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 AJW71632.1 - 0.00041 19.8 0.5 0.076 12.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4_3 PF12798.2 AJW71632.1 - 0.0027 18.1 5.4 0.0027 18.1 3.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Miro PF08477.8 AJW71632.1 - 0.0027 18.1 0.1 0.52 10.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 AJW71632.1 - 0.0028 17.5 0.3 3.2 7.7 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 AJW71632.1 - 0.01 16.5 11.9 0.1 13.3 7.1 2.5 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 AJW71632.1 - 0.011 16.0 3.1 0.011 16.0 2.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 AJW71632.1 - 0.017 15.4 12.4 0.05 13.8 8.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_16 PF13191.1 AJW71632.1 - 0.018 14.9 2.0 0.08 12.9 0.1 2.7 3 1 0 3 3 2 0 AAA ATPase domain NB-ARC PF00931.17 AJW71632.1 - 0.033 13.0 0.1 2.7 6.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Fer4_8 PF13183.1 AJW71632.1 - 0.047 13.7 0.9 0.047 13.7 0.6 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain RuvB_N PF05496.7 AJW71632.1 - 0.078 12.0 0.2 2.9 6.8 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AJW71632.1 - 0.093 12.9 0.4 2.6 8.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AJW71632.1 - 0.094 12.6 0.6 4.3 7.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.18 AJW71632.1 - 0.13 12.2 2.1 0.67 9.9 0.2 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.1 AJW71632.1 - 0.23 10.8 0.5 13 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 AJW71632.1 - 2.4 8.5 10.0 0.29 11.4 0.8 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 AJW71632.1 - 3 8.4 13.1 0.11 13.0 2.9 2.6 1 1 0 1 1 1 0 4Fe-4S single cluster domain AAA_23 PF13476.1 AJW71632.1 - 8.8 6.5 11.2 13 5.9 0.6 3.3 2 2 0 2 2 2 0 AAA domain DUF1469 PF07332.6 AJW71633.1 - 0.0088 15.7 0.8 0.011 15.4 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) DUF1011 PF06237.7 AJW71633.1 - 0.23 11.3 2.0 1.6 8.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1011) DUF1049 PF06305.6 AJW71633.1 - 4.4 6.8 7.1 1.3 8.5 3.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) Acetyltransf_1 PF00583.19 AJW71634.1 - 1.4e-16 60.2 0.2 2.1e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AJW71634.1 - 2.9e-09 37.0 0.0 4.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AJW71634.1 - 6.9e-09 35.7 0.4 1e-08 35.1 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AJW71634.1 - 7.6e-09 35.2 0.1 3.5e-08 33.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 AJW71634.1 - 1.8e-06 27.8 0.0 3.3e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AJW71634.1 - 0.00019 21.4 0.2 0.00027 20.9 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AJW71634.1 - 0.0018 18.1 0.0 0.0055 16.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AJW71634.1 - 0.0022 18.1 0.1 0.0033 17.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AJW71634.1 - 0.088 12.7 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M50 PF02163.17 AJW71635.1 - 1.1e-16 60.3 8.5 1.5e-15 56.6 4.6 2.8 2 1 0 2 2 2 1 Peptidase family M50 Pribosyltran PF00156.22 AJW71637.1 - 1.1e-14 54.1 0.3 2.1e-14 53.3 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 AJW71637.1 - 0.00016 21.0 0.2 0.00074 18.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.1 AJW71637.1 - 0.00037 19.7 0.1 0.00049 19.3 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SmpB PF01668.13 AJW71637.1 - 0.097 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 SmpB protein TENA_THI-4 PF03070.11 AJW71638.1 - 1.8e-16 60.5 0.2 2.1e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.1 AJW71638.1 - 6.5e-08 32.6 0.0 2.8e-07 30.6 0.0 1.9 1 1 1 2 2 2 1 Iron-containing redox enzyme DUF2153 PF09921.4 AJW71638.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) polyprenyl_synt PF00348.12 AJW71639.1 - 2.5e-43 147.8 0.1 3.7e-43 147.2 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Oxidored_q1 PF00361.15 AJW71640.1 - 7.5e-61 205.7 22.2 7.5e-61 205.7 15.4 2.8 2 1 0 2 2 2 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1 PF00361.15 AJW71641.1 - 8.8e-55 185.8 21.3 2.3e-50 171.3 14.3 3.5 4 0 0 4 4 4 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 AJW71641.1 - 6.6e-12 44.8 2.2 3e-11 42.6 1.5 2.2 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q1_C PF01010.14 AJW71641.1 - 0.0017 17.9 0.3 0.019 14.4 0.1 2.2 1 1 1 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Oxidored_q2 PF00420.19 AJW71641.1 - 0.011 15.3 1.8 0.011 15.3 1.3 4.7 5 1 0 5 5 5 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Oxidored_q1 PF00361.15 AJW71642.1 - 7.4e-63 212.3 23.9 7.4e-63 212.3 16.6 2.3 2 0 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q2 PF00420.19 AJW71643.1 - 8.6e-23 79.7 4.4 1e-22 79.5 3.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Oxidored_q3 PF00499.15 AJW71644.1 - 2e-20 73.0 7.3 2.6e-20 72.6 5.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MIG-14_Wnt-bd PF06664.7 AJW71644.1 - 0.0025 16.7 0.5 0.0032 16.3 0.4 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF4040 PF13244.1 AJW71644.1 - 0.014 15.3 9.9 0.014 15.3 6.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) NfeD PF01957.13 AJW71644.1 - 0.99 9.5 14.2 0.14 12.2 6.1 2.1 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4389 PF14333.1 AJW71644.1 - 2.2 8.0 6.7 20 4.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) UPF0104 PF03706.8 AJW71644.1 - 2.2 7.4 16.2 0.27 10.4 6.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) DUF4131 PF13567.1 AJW71644.1 - 4 6.8 7.2 6.7 6.0 3.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HlyIII PF03006.15 AJW71644.1 - 6.5 6.0 10.1 0.39 10.0 3.4 1.5 2 0 0 2 2 2 0 Haemolysin-III related Fer4 PF00037.22 AJW71645.1 - 6.3e-12 44.5 10.8 2.6e-09 36.2 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AJW71645.1 - 4.1e-10 39.3 17.9 3.1e-07 30.0 6.9 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 AJW71645.1 - 1.2e-09 38.4 9.5 1.9e-09 37.7 6.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJW71645.1 - 1.1e-08 34.8 20.2 3.5e-06 26.7 7.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJW71645.1 - 2.5e-08 33.3 10.5 6.8e-05 22.5 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 AJW71645.1 - 4.9e-07 29.9 8.9 8.5e-07 29.1 6.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AJW71645.1 - 4.4e-06 26.6 18.3 0.00014 21.7 7.1 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJW71645.1 - 5.1e-06 26.1 1.8 5.1e-06 26.1 1.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.1 AJW71645.1 - 5.3e-06 26.6 7.4 0.0031 17.8 0.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 AJW71645.1 - 1.2e-05 25.8 17.4 0.00053 20.6 6.7 1.8 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 AJW71645.1 - 1.8e-05 24.6 8.5 0.0026 17.9 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AJW71645.1 - 0.00036 21.0 4.4 0.093 13.3 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 AJW71645.1 - 0.0028 17.9 4.9 0.25 11.7 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 AJW71645.1 - 0.0031 17.9 17.3 0.0057 17.1 2.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.1 AJW71645.1 - 0.0031 17.9 11.5 0.0061 16.9 0.8 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain DUF2607 PF10795.4 AJW71645.1 - 0.042 13.6 0.2 0.071 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) NADHdh PF00146.16 AJW71646.1 - 1.5e-78 264.0 16.1 2.5e-78 263.2 11.2 1.3 1 0 0 1 1 1 1 NADH dehydrogenase Oxidored_q6 PF01058.17 AJW71647.1 - 4.7e-25 87.7 0.1 6.5e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.14 AJW71648.1 - 2.1e-15 56.4 1.5 3.3e-15 55.7 1.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 AhpC-TSA PF00578.16 AJW71649.1 - 4.4e-33 113.6 0.0 5e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJW71649.1 - 2.4e-23 82.3 0.0 2.7e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 AJW71649.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.4 2 0 0 2 2 2 0 SCO1/SenC AhpC-TSA_2 PF13911.1 AJW71649.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme DUF3823 PF12866.2 AJW71649.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) Biotin_lipoyl PF00364.17 AJW71650.1 - 2.4e-18 65.5 5.1 2.4e-18 65.5 3.5 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 AJW71650.1 - 2.9e-15 55.6 2.0 2.1e-10 40.1 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 AJW71650.1 - 2.8e-07 30.1 0.7 0.00022 20.6 0.0 2.1 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 AJW71650.1 - 3.2e-06 27.4 0.3 0.04 14.2 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 AJW71650.1 - 0.00014 21.1 6.4 0.0027 16.9 0.1 2.9 2 1 1 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.1 AJW71650.1 - 0.00024 20.7 1.6 0.00044 19.9 1.1 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 AJW71650.1 - 0.00067 19.3 0.4 0.00067 19.3 0.3 1.9 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M23 PF01551.17 AJW71650.1 - 0.0043 17.0 0.9 0.38 10.8 0.0 2.8 2 1 1 3 3 3 1 Peptidase family M23 QRPTase_N PF02749.11 AJW71650.1 - 0.0067 16.2 0.1 0.087 12.6 0.0 2.2 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.14 AJW71650.1 - 0.0068 16.0 3.2 0.0076 15.9 1.1 2.0 2 1 0 2 2 2 1 Glycine cleavage H-protein PYNP_C PF07831.8 AJW71650.1 - 0.025 14.0 0.2 0.4 10.1 0.1 2.2 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain NQRA PF05896.6 AJW71650.1 - 0.055 12.6 0.7 0.081 12.1 0.5 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF3862 PF12978.2 AJW71650.1 - 0.1 12.2 0.4 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3862) DUF3627 PF12299.3 AJW71650.1 - 0.1 12.6 0.6 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) CPSase_L_D2 PF02786.12 AJW71651.1 - 3.1e-71 239.0 0.1 4.7e-71 238.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AJW71651.1 - 1.2e-43 147.6 0.1 3e-43 146.4 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AJW71651.1 - 3.8e-32 110.4 0.0 7.2e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 AJW71651.1 - 1.9e-19 70.1 0.1 4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AJW71651.1 - 6.1e-15 54.7 0.0 3.4e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AJW71651.1 - 2.1e-11 43.4 0.2 4.8e-11 42.2 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 AJW71651.1 - 6.4e-10 38.8 0.0 3.7e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 AJW71651.1 - 1.9e-09 37.1 0.4 5.4e-09 35.7 0.3 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AJW71651.1 - 5.5e-08 32.8 0.1 9.7e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF3182 PF11379.3 AJW71651.1 - 0.046 12.4 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) ATP-grasp_5 PF13549.1 AJW71651.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Carboxyl_trans PF01039.17 AJW71652.1 - 2.9e-188 626.2 0.1 3.3e-188 626.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 AJW71652.1 - 3.2e-06 26.5 0.0 7.3e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) DUF4428 PF14471.1 AJW71653.1 - 3.7 7.3 18.8 5.6 6.7 0.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) AAA PF00004.24 AJW71654.1 - 7.9e-13 48.7 0.0 2.1e-12 47.4 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AJW71654.1 - 3.8e-10 39.0 1.6 3.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 AJW71654.1 - 9.4e-08 31.3 0.0 1.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AJW71654.1 - 1.2e-05 26.1 0.1 3.9e-05 24.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 AJW71654.1 - 8.7e-05 21.3 0.0 0.00019 20.2 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 AJW71654.1 - 0.00015 21.6 0.0 0.00054 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AJW71654.1 - 0.0019 18.0 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AJW71654.1 - 0.002 18.2 0.0 0.044 13.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 AJW71654.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AJW71654.1 - 0.0027 17.3 0.0 0.0056 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AJW71654.1 - 0.0041 16.8 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AJW71654.1 - 0.0047 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 AJW71654.1 - 0.0056 15.8 0.1 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AJW71654.1 - 0.006 16.8 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AJW71654.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 AJW71654.1 - 0.0078 15.6 0.1 0.025 13.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.10 AJW71654.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 AJW71654.1 - 0.012 14.5 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 AJW71654.1 - 0.017 15.0 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AJW71654.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 AJW71654.1 - 0.022 14.9 0.0 0.061 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 AJW71654.1 - 0.031 14.5 0.1 0.17 12.1 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 AJW71654.1 - 0.035 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 AJW71654.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Inositol_P PF00459.20 AJW71656.1 - 3.5e-30 105.2 0.0 4.1e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 AJW71656.1 - 6.7e-06 25.1 0.0 1.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase NAD_binding_1 PF00175.16 AJW71657.1 - 1.9e-12 47.6 0.0 4.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AJW71657.1 - 3.3e-11 43.1 0.0 5.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AJW71657.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain DUF3115 PF11312.3 AJW71657.1 - 0.13 11.0 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) DUF1059 PF06348.6 AJW71658.1 - 3.8e-06 26.6 0.3 4.1e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) GlutR_N PF05201.10 AJW71659.1 - 1.3e-30 105.9 0.0 1.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 AJW71659.1 - 1.8e-13 50.7 0.0 3.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 AJW71659.1 - 0.00098 19.5 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ABC_tran_2 PF12848.2 AJW71660.1 - 0.04 13.7 0.1 0.04 13.7 0.1 3.4 2 1 2 4 4 4 0 ABC transporter Lyase_1 PF00206.15 AJW71661.1 - 5.4e-51 173.6 0.0 3.1e-50 171.1 0.0 1.9 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.1 AJW71661.1 - 5.7e-15 55.1 0.0 1.2e-13 50.9 0.0 2.8 3 0 0 3 3 3 1 Argininosuccinate lyase C-terminal UPF0449 PF15136.1 AJW71661.1 - 0.1 12.8 0.3 0.4 10.9 0.2 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF59 PF01883.14 AJW71662.1 - 8.5e-15 54.4 0.1 1.2e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF59 HMA PF00403.21 AJW71662.1 - 0.15 12.2 0.7 0.76 9.9 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain DUF3908 PF13048.1 AJW71662.1 - 0.18 11.7 2.6 0.16 11.9 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3908) Fer2_3 PF13085.1 AJW71663.1 - 1.1e-30 105.6 0.0 2.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 AJW71663.1 - 3.8e-12 46.0 4.7 8.4e-12 44.9 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AJW71663.1 - 2.4e-10 40.6 6.1 9.5e-09 35.5 0.2 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 AJW71663.1 - 1e-08 35.3 1.5 1e-08 35.3 1.1 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AJW71663.1 - 1.2e-08 35.1 2.4 1.2e-08 35.1 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJW71663.1 - 2.2e-08 33.7 2.5 2.2e-08 33.7 1.8 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 AJW71663.1 - 2.4e-08 34.2 14.0 7.1e-07 29.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 AJW71663.1 - 0.00013 21.6 1.2 0.00022 20.9 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 AJW71663.1 - 0.00014 21.3 1.6 0.00014 21.3 1.1 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.2 AJW71663.1 - 0.00015 21.4 13.2 0.00018 21.2 1.2 3.3 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_16 PF13484.1 AJW71663.1 - 0.00086 20.0 4.3 0.00086 20.0 3.0 2.3 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.2 AJW71663.1 - 0.0059 16.4 2.1 0.0059 16.4 1.4 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_4 PF12800.2 AJW71663.1 - 0.077 13.3 1.9 0.077 13.3 1.3 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.2 AJW71663.1 - 0.15 12.6 0.9 0.15 12.6 0.6 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_21 PF14697.1 AJW71663.1 - 1.2 9.0 15.4 0.19 11.6 5.4 3.0 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 AJW71663.1 - 2.5 8.7 8.4 0.65 10.6 0.2 2.9 3 0 0 3 3 2 0 4Fe-4S single cluster domain Sdh_cyt PF01127.17 AJW71664.1 - 5.1e-08 32.7 4.2 6.4e-08 32.4 2.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.14 AJW71664.1 - 0.2 11.7 3.5 0.23 11.5 2.4 1.3 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF4405 PF14358.1 AJW71664.1 - 0.55 10.4 5.2 0.51 10.5 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Sdh_cyt PF01127.17 AJW71665.1 - 8e-09 35.3 3.3 1.4e-08 34.5 2.1 1.5 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DDE_Tnp_1_2 PF13586.1 AJW71665.1 - 0.19 11.9 1.8 1 9.5 0.0 2.5 3 0 0 3 3 3 0 Transposase DDE domain Flavi_M PF01004.14 AJW71665.1 - 0.52 9.7 0.0 0.52 9.7 0.0 2.0 3 0 0 3 3 3 0 Flavivirus envelope glycoprotein M DUF2196 PF09962.4 AJW71665.1 - 0.74 9.6 2.6 6.6 6.6 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2196) FAD_binding_2 PF00890.19 AJW71666.1 - 8e-98 328.0 0.1 1.1e-97 327.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AJW71666.1 - 3.4e-38 130.4 1.1 5.5e-38 129.7 0.7 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 AJW71666.1 - 3.9e-07 30.1 1.2 0.00073 19.4 0.5 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AJW71666.1 - 0.00036 19.7 0.5 0.003 16.6 0.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AJW71666.1 - 0.0016 17.4 0.1 0.06 12.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 AJW71666.1 - 0.01 14.7 0.0 0.22 10.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 AJW71666.1 - 0.016 13.6 0.1 1 7.7 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 AJW71666.1 - 0.026 13.6 1.0 0.065 12.3 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 AJW71666.1 - 0.035 13.0 0.2 0.076 11.9 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein PadR PF03551.9 AJW71667.1 - 5.2e-11 42.1 0.2 1e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.1 AJW71667.1 - 5.5e-06 26.1 0.2 2.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix Mrr_N PF14338.1 AJW71667.1 - 0.00038 20.4 0.0 0.04 13.9 0.0 2.5 2 0 0 2 2 2 1 Mrr N-terminal domain Rota_NSP4 PF01452.11 AJW71667.1 - 0.036 13.3 1.1 0.049 12.9 0.7 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein Stork_head PF10264.4 AJW71667.1 - 0.084 13.0 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain AphA_like PF14557.1 AJW71667.1 - 0.087 12.3 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF1451 PF07295.6 AJW71667.1 - 0.62 9.8 3.4 1.1 8.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Lactamase_B PF00753.22 AJW71668.1 - 7.6e-13 48.5 2.8 1e-12 48.1 1.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AJW71668.1 - 0.0015 18.1 0.1 0.0023 17.5 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PEP_mutase PF13714.1 AJW71669.1 - 1e-54 185.2 0.0 1.2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 AJW71669.1 - 2.6e-17 62.2 0.0 4.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 AJW71669.1 - 0.0097 15.0 0.1 0.38 9.8 0.0 2.8 2 1 1 3 3 3 1 Ketopantoate hydroxymethyltransferase HisG_C PF08029.6 AJW71669.1 - 0.071 13.0 0.0 0.55 10.2 0.0 2.4 3 0 0 3 3 3 0 HisG, C-terminal domain Alba PF01918.16 AJW71670.1 - 9.8e-10 37.8 0.1 1.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 AJW71670.1 - 0.044 13.4 0.6 2.3 7.8 0.0 2.1 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P PepSY_2 PF13670.1 AJW71670.1 - 0.081 12.8 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain HEAT_2 PF13646.1 AJW71671.1 - 2.2e-15 56.7 0.1 4.5e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 AJW71671.1 - 2.1e-11 42.9 0.0 0.08 13.0 0.0 4.2 4 0 0 4 4 4 4 HEAT repeat HEAT_EZ PF13513.1 AJW71671.1 - 1.7e-09 37.8 0.0 0.074 13.5 0.0 3.9 3 1 1 4 4 4 3 HEAT-like repeat Cohesin_HEAT PF12765.2 AJW71671.1 - 0.00025 20.9 0.8 0.54 10.2 0.0 2.9 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 AJW71671.1 - 0.033 14.1 0.3 2.1 8.3 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2435) YopD PF05844.7 AJW71671.1 - 0.046 12.7 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 YopD protein Arm PF00514.18 AJW71671.1 - 0.12 12.2 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat NAD_binding_1 PF00175.16 AJW71672.1 - 1.4e-13 51.3 0.0 3.2e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AJW71672.1 - 3.3e-10 39.9 0.0 4.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AJW71672.1 - 0.14 12.0 0.2 0.56 10.1 0.1 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain CTP_transf_2 PF01467.21 AJW71673.1 - 0.00012 22.1 0.0 0.00034 20.6 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase Aminotran_4 PF01063.14 AJW71674.1 - 5.9e-41 140.4 0.0 7.2e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV GFO_IDH_MocA PF01408.17 AJW71675.1 - 4.3e-25 88.5 0.0 8.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AJW71675.1 - 1.6e-08 34.3 0.0 3.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.14 AJW71675.1 - 0.0065 15.6 0.0 0.016 14.3 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M73 PF12389.3 AJW71675.1 - 0.0076 15.7 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Camelysin metallo-endopeptidase Semialdhyde_dh PF01118.19 AJW71675.1 - 0.098 12.9 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Trm112p PF03966.11 AJW71676.1 - 7.4e-09 35.8 0.2 2.1e-08 34.3 0.1 1.8 1 1 0 1 1 1 1 Trm112p-like protein Hexapep PF00132.19 AJW71677.1 - 7.4e-27 91.6 17.6 9.7e-11 40.6 0.8 4.2 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJW71677.1 - 2.6e-16 58.8 15.1 9.7e-11 41.0 1.7 4.7 4 1 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase Urease_alpha PF00449.15 AJW71677.1 - 0.5 10.5 5.2 1.2 9.2 3.6 1.8 1 1 0 1 1 1 0 Urease alpha-subunit, N-terminal domain DUF1980 PF09323.5 AJW71678.1 - 0.025 14.3 4.1 0.032 13.9 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) NfeD PF01957.13 AJW71678.1 - 0.48 10.5 6.9 0.53 10.4 4.8 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Vpu PF00558.14 AJW71678.1 - 3 7.4 5.3 4.4 6.9 3.7 1.3 1 0 0 1 1 1 0 Vpu protein Glycos_transf_4 PF00953.16 AJW71679.1 - 6.2e-26 91.0 17.0 6.2e-26 91.0 11.8 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 Big_3_3 PF13750.1 AJW71679.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DEAD PF00270.24 AJW71680.1 - 2.3e-28 98.8 0.1 1e-27 96.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HHH_5 PF14520.1 AJW71680.1 - 1.4e-10 41.1 1.1 4.4e-10 39.5 0.8 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.26 AJW71680.1 - 2.7e-10 39.9 0.0 6.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AJW71680.1 - 1.2e-07 31.6 0.1 7.7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sec63 PF02889.11 AJW71680.1 - 2.7e-06 26.8 1.4 3e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 Sec63 Brl domain HHH_2 PF12826.2 AJW71680.1 - 4.7e-06 26.3 0.4 3.1e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.4 AJW71680.1 - 0.00022 20.7 0.0 0.00092 18.7 0.0 2.1 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Arch_ATPase PF01637.13 AJW71680.1 - 0.012 15.3 0.2 0.012 15.3 0.1 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 AJW71680.1 - 0.018 14.4 0.0 0.11 11.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain KIP1 PF07765.7 AJW71680.1 - 0.12 12.1 1.4 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 KIP1-like protein MCM PF00493.18 AJW71681.1 - 7.5e-123 409.5 0.3 1e-122 409.1 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AJW71681.1 - 1.5e-15 57.7 1.7 4e-15 56.3 0.2 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AJW71681.1 - 3.1e-06 26.5 0.0 0.00025 20.2 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AJW71681.1 - 3.8e-06 26.6 0.1 0.0002 21.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AJW71681.1 - 0.0018 17.8 0.0 0.0059 16.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sld5 PF05916.6 AJW71682.1 - 4.8e-08 33.2 0.4 6.8e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein NADPH_Ox PF08414.5 AJW71682.1 - 0.018 15.0 0.3 1.3 9.1 0.3 2.2 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase His_kinase PF06580.8 AJW71682.1 - 0.026 14.4 0.2 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase DNA_pol3_delta2 PF13177.1 AJW71683.1 - 1.3e-15 57.4 0.2 3.2e-13 49.6 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AJW71683.1 - 9.6e-13 48.4 0.6 4e-12 46.4 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 AJW71683.1 - 1.4e-12 47.4 2.9 3.8e-12 46.0 0.4 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.8 AJW71683.1 - 1.1e-07 31.5 0.1 2.4e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 AJW71683.1 - 1.4e-07 30.6 0.1 0.0092 14.7 0.0 2.5 1 1 2 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 AJW71683.1 - 3.3e-06 26.3 0.0 3.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AJW71683.1 - 6.1e-06 26.4 0.2 0.1 12.7 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.6 AJW71683.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 AJW71683.1 - 0.0026 17.2 0.7 0.33 10.4 0.0 2.5 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 AJW71683.1 - 0.011 15.6 0.0 0.78 9.7 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 AJW71683.1 - 0.011 15.1 4.1 1 8.7 2.9 2.5 1 1 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 AJW71683.1 - 0.016 14.0 0.1 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.11 AJW71683.1 - 0.018 14.2 0.2 4.1 6.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 AJW71683.1 - 0.02 15.1 3.4 0.067 13.5 0.6 2.7 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 AJW71683.1 - 0.023 13.8 0.1 2.7 7.0 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 AJW71683.1 - 0.035 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 AJW71683.1 - 0.042 13.9 0.1 0.96 9.4 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 AJW71683.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 AJW71683.1 - 0.12 12.0 0.4 1.3 8.7 0.3 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 AJW71683.1 - 0.13 12.0 0.6 1.6 8.5 0.4 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 AJW71683.1 - 0.16 11.3 0.5 0.57 9.5 0.3 2.1 1 1 0 1 1 1 0 AAA domain RHH_1 PF01402.16 AJW71683.1 - 0.28 11.1 3.8 18 5.3 0.0 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Fer4_7 PF12838.2 AJW71684.1 - 2.5e-09 37.3 4.7 0.00043 20.5 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 AJW71684.1 - 3e-09 36.0 9.6 0.00011 21.6 2.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AJW71684.1 - 1.3e-08 34.7 5.8 3.5e-08 33.3 4.1 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJW71684.1 - 3e-08 33.3 3.6 0.001 18.8 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 AJW71684.1 - 2e-07 31.6 2.8 0.00045 20.8 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 AJW71684.1 - 2e-07 31.1 6.9 6.6e-07 29.5 4.8 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 AJW71684.1 - 7.7e-07 29.3 3.5 1.5e-06 28.4 2.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJW71684.1 - 1e-06 28.4 8.0 1.7e-05 24.4 6.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJW71684.1 - 4.6e-06 26.2 11.0 0.0013 18.4 3.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 AJW71684.1 - 0.00035 20.9 9.3 0.0011 19.3 4.9 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 AJW71684.1 - 0.00044 20.0 10.2 0.035 14.0 0.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AJW71684.1 - 0.00053 20.4 6.4 0.1 13.1 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_4 PF12800.2 AJW71684.1 - 0.0077 16.4 10.6 0.16 12.3 0.9 2.7 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AJW71684.1 - 0.011 16.0 8.9 1.3 9.4 2.3 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 AJW71684.1 - 0.012 16.1 15.6 0.22 12.1 4.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2761 PF10959.3 AJW71684.1 - 0.12 12.0 0.2 0.25 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2761) Fer4 PF00037.22 AJW71685.1 - 6.6e-10 38.1 11.9 5e-06 25.8 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AJW71685.1 - 1.4e-09 38.1 4.4 0.00026 21.2 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 AJW71685.1 - 1.5e-08 34.4 0.7 0.0021 18.0 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 AJW71685.1 - 8.2e-08 32.4 6.7 5.5e-07 29.7 4.6 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AJW71685.1 - 2e-07 30.7 2.4 0.0009 19.0 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 AJW71685.1 - 4.3e-07 29.6 19.7 2.5e-05 23.9 6.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AJW71685.1 - 4.5e-07 29.4 12.5 0.00066 19.4 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 AJW71685.1 - 3.5e-06 26.6 11.7 0.0058 16.4 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 AJW71685.1 - 5.3e-06 26.9 5.7 0.0047 17.4 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_16 PF13484.1 AJW71685.1 - 8.7e-06 26.3 7.1 0.0019 18.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 AJW71685.1 - 2.7e-05 24.4 8.6 0.00011 22.5 4.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 AJW71685.1 - 3.3e-05 24.1 5.3 0.03 14.7 0.1 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_4 PF12800.2 AJW71685.1 - 4.9e-05 23.3 7.1 0.037 14.3 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AJW71685.1 - 0.0001 22.5 4.7 0.0017 18.6 4.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain BCA_ABC_TP_C PF12399.3 AJW71685.1 - 0.00059 19.4 0.1 0.0013 18.3 0.1 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter Fer4_11 PF13247.1 AJW71685.1 - 0.0048 16.7 1.7 2.1 8.2 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 AJW71685.1 - 0.049 14.1 16.2 0.19 12.3 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain eIF-6 PF01912.13 AJW71686.1 - 4.5e-68 228.2 1.1 5.7e-68 227.9 0.8 1.1 1 0 0 1 1 1 1 eIF-6 family PrpR_N PF06506.6 AJW71686.1 - 0.061 12.7 0.0 9.9 5.5 0.0 2.2 1 1 1 2 2 2 0 Propionate catabolism activator tRNA-synt_His PF13393.1 AJW71687.1 - 4.3e-48 163.9 0.0 6.4e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AJW71687.1 - 4.9e-16 58.7 0.0 9.1e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AJW71687.1 - 7e-11 41.9 0.1 3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.15 AJW71687.1 - 0.00032 19.9 0.0 0.00066 18.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) RPT PF13446.1 AJW71687.1 - 0.0014 17.9 0.2 0.003 16.9 0.1 1.6 1 0 0 1 1 1 1 A repeated domain in UCH-protein Aldo_ket_red PF00248.16 AJW71688.1 - 7.4e-50 169.3 0.0 8.4e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Excalibur PF05901.6 AJW71689.1 - 0.0023 18.2 0.7 0.0061 16.8 0.5 1.7 1 0 0 1 1 1 1 Excalibur calcium-binding domain SNase PF00565.12 AJW71689.1 - 0.023 14.9 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal nuclease homologue Gmad2 PF10648.4 AJW71689.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination IpaB_EvcA PF03278.8 AJW71690.1 - 0.46 9.7 11.7 0.014 14.6 2.0 2.8 3 1 2 5 5 5 0 IpaB/EvcA family AsiA PF09010.5 AJW71690.1 - 0.66 9.8 8.1 18 5.3 0.6 3.9 4 0 0 4 4 4 0 Anti-Sigma Factor A SieB PF14163.1 AJW71690.1 - 3.2 7.2 5.7 0.87 9.1 0.4 2.3 1 1 1 2 2 2 0 Superinfection exclusion protein B OmpH PF03938.9 AJW71690.1 - 6.9 6.5 15.8 44 3.9 0.0 3.4 2 2 0 2 2 2 0 Outer membrane protein (OmpH-like) UDG PF03167.14 AJW71691.1 - 8e-28 96.8 0.0 1e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Imm5 PF14423.1 AJW71691.1 - 0.057 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 HD_3 PF13023.1 AJW71693.1 - 0.076 12.7 0.1 0.081 12.6 0.0 1.0 1 0 0 1 1 1 0 HD domain GSDH PF07995.6 AJW71694.1 - 5.5e-92 308.3 0.0 6.7e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 AJW71694.1 - 0.086 12.8 0.0 6.8 6.8 0.0 3.5 4 0 0 4 4 4 0 NHL repeat DUF72 PF01904.13 AJW71695.1 - 1.9e-50 171.7 0.0 2.2e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 SNARE_assoc PF09335.6 AJW71696.1 - 1.6e-19 70.3 6.5 1.8e-19 70.1 4.0 1.4 1 1 0 1 1 1 1 SNARE associated Golgi protein ADH_N PF08240.7 AJW71698.1 - 2.3e-23 82.0 0.3 3.6e-23 81.4 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AJW71698.1 - 0.00016 21.2 0.0 0.0008 18.9 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 AJW71698.1 - 0.00064 19.8 0.0 0.00099 19.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 AJW71698.1 - 0.037 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyoxalase_2 PF12681.2 AJW71699.1 - 7.5e-10 39.3 0.0 1.1e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AJW71699.1 - 0.00055 19.9 0.0 0.00056 19.8 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HD_4 PF13328.1 AJW71700.1 - 3.7e-19 68.9 0.1 4.9e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 HD domain RSS_P20 PF11757.3 AJW71700.1 - 0.036 14.2 2.2 0.26 11.3 0.3 2.7 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like Archease PF01951.11 AJW71701.1 - 1e-33 116.2 0.5 1.1e-33 116.0 0.3 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) DUF3888 PF13027.1 AJW71701.1 - 0.035 13.9 0.4 0.93 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) DUF1410 PF07198.6 AJW71701.1 - 0.11 12.8 0.0 1.4 9.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1410) He_PIG PF05345.7 AJW71702.1 - 0.0013 18.7 1.0 0.0032 17.4 0.1 2.1 2 0 0 2 2 2 1 Putative Ig domain Occludin_ELL PF07303.8 AJW71702.1 - 5.3 7.8 9.4 11 6.8 0.2 2.8 3 0 0 3 3 3 0 Occludin homology domain fn3 PF00041.16 AJW71703.1 - 1.2e-39 134.3 14.1 1.2e-15 57.4 2.1 4.7 4 1 0 4 4 4 4 Fibronectin type III domain NHL PF01436.16 AJW71703.1 - 7.7e-30 101.3 6.4 3.9e-07 29.6 0.0 6.4 6 0 0 6 6 6 5 NHL repeat Lactonase PF10282.4 AJW71703.1 - 2.7e-09 36.5 5.5 0.047 12.7 0.1 5.3 4 1 1 5 5 5 4 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.15 AJW71703.1 - 3.6e-08 33.2 0.0 1.9 8.4 0.0 5.4 5 0 0 5 5 5 1 Arylesterase SGL PF08450.7 AJW71703.1 - 3.2e-07 29.9 5.5 0.11 11.8 0.0 5.0 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region He_PIG PF05345.7 AJW71703.1 - 0.00015 21.6 3.9 0.01 15.8 0.1 3.9 3 0 0 3 3 3 1 Putative Ig domain SusE PF14292.1 AJW71703.1 - 0.00093 19.0 3.6 0.05 13.4 1.3 3.7 3 0 0 3 3 3 1 SusE outer membrane protein DUF1900 PF08954.6 AJW71703.1 - 0.032 13.7 0.1 3 7.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) MRJP PF03022.11 AJW71703.1 - 0.073 12.2 0.8 3.5 6.7 0.1 3.0 3 1 0 3 3 3 0 Major royal jelly protein Secretin_N PF03958.12 AJW71703.1 - 0.12 12.5 1.7 7.6 6.7 0.0 3.3 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain Occludin_ELL PF07303.8 AJW71703.1 - 0.41 11.4 3.6 21 5.9 0.2 2.5 2 0 0 2 2 2 0 Occludin homology domain TF_Zn_Ribbon PF08271.7 AJW71704.1 - 0.0073 15.6 1.2 0.56 9.5 0.1 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 AJW71704.1 - 0.025 14.0 1.1 0.073 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF1451 PF07295.6 AJW71704.1 - 0.035 13.8 0.2 0.041 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) zf-C2H2_6 PF13912.1 AJW71704.1 - 0.06 13.2 1.3 0.67 9.9 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 AJW71704.1 - 0.069 12.8 0.5 0.093 12.4 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.2 AJW71704.1 - 0.11 12.2 0.9 4.8 7.0 0.1 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-RING_5 PF14634.1 AJW71704.1 - 0.15 11.7 1.1 0.22 11.2 0.7 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-C2H2 PF00096.21 AJW71704.1 - 0.18 12.2 1.7 8.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_3 PF13878.1 AJW71704.1 - 0.43 10.1 1.8 0.54 9.8 0.1 1.9 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Thioredoxin PF00085.15 AJW71705.1 - 5.7e-30 103.0 0.0 7.9e-30 102.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AJW71705.1 - 8.2e-10 38.6 0.6 6.1e-08 32.6 0.0 2.5 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AJW71705.1 - 1.8e-09 37.7 0.7 1.2e-08 35.0 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 AJW71705.1 - 5.1e-07 29.3 0.1 1.5e-06 27.8 0.1 1.7 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 AJW71705.1 - 3.3e-06 26.7 0.1 6.1e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 AJW71705.1 - 4.8e-05 22.2 0.0 5.3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.1 AJW71705.1 - 0.00012 21.9 0.5 0.00029 20.7 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 AJW71705.1 - 0.00038 20.1 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 AJW71705.1 - 0.002 17.8 0.1 0.0048 16.5 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.1 AJW71705.1 - 0.002 17.9 0.1 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 AJW71705.1 - 0.0094 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE TraF PF13728.1 AJW71705.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF836 PF05768.9 AJW71705.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 AJW71705.1 - 0.087 12.8 0.0 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin Toxin-deaminase PF14424.1 AJW71705.1 - 0.088 12.7 0.1 0.11 12.4 0.1 1.4 1 1 0 1 1 1 0 The BURPS668_1122 family of deaminases GTP_EFTU PF00009.22 AJW71706.1 - 2.2e-33 115.2 0.0 5.4e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AJW71706.1 - 1.2e-23 83.0 0.8 3.4e-23 81.5 0.6 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.1 AJW71706.1 - 2.2e-08 33.6 0.0 2.2e-08 33.6 0.0 2.5 4 0 0 4 4 4 1 Elongation factor Tu domain 4 Miro PF08477.8 AJW71706.1 - 9.7e-08 32.5 0.1 6.2e-07 29.9 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 AJW71706.1 - 1.5e-07 31.3 0.1 6.3e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AJW71706.1 - 2.7e-05 23.8 0.0 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU_D2 PF03144.20 AJW71706.1 - 6.1e-05 23.0 0.1 0.0005 20.1 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 AJW71706.1 - 0.00018 21.3 0.2 0.052 13.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Ras PF00071.17 AJW71706.1 - 0.0027 17.1 0.0 0.014 14.7 0.0 2.1 1 1 0 1 1 1 1 Ras family cobW PF02492.14 AJW71706.1 - 0.02 14.3 0.2 2 7.8 0.1 2.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NDK PF00334.14 AJW71707.1 - 6.4e-50 168.4 0.0 7.1e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ribosomal_S28e PF01200.13 AJW71708.1 - 8.9e-29 99.0 6.0 9.5e-29 98.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L7Ae PF01248.21 AJW71709.1 - 2e-25 88.1 0.1 2.4e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 AJW71709.1 - 0.028 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF3055 PF11256.3 AJW71709.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3055) PGM_PMM_I PF02878.11 AJW71710.1 - 1.2e-35 122.0 0.0 2e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AJW71710.1 - 1.8e-23 82.8 0.0 6.1e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 AJW71710.1 - 4.3e-20 71.8 0.0 7.1e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 AJW71710.1 - 1.9e-12 46.9 0.0 4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF387 PF04079.11 AJW71710.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Formyl_trans_N PF00551.14 AJW71711.1 - 5.4e-42 143.3 0.1 9e-42 142.6 0.0 1.4 2 0 0 2 2 2 1 Formyl transferase ACT_6 PF13740.1 AJW71711.1 - 3.5e-09 36.2 0.0 9e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 AJW71711.1 - 0.021 15.1 1.1 0.055 13.8 0.0 2.3 3 0 0 3 3 3 0 ACT domain ACT PF01842.20 AJW71711.1 - 0.027 13.9 0.2 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 ACT domain DUF4411 PF14367.1 AJW71711.1 - 0.031 13.9 0.1 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Creatininase PF02633.9 AJW71712.1 - 6.5e-56 189.0 0.0 8e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Flagellin_C PF00700.16 AJW71713.1 - 0.011 15.8 0.5 0.011 15.8 0.3 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region But2 PF09792.4 AJW71713.1 - 0.18 11.5 1.6 2.4 7.9 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain Rib_5-P_isom_A PF06026.9 AJW71714.1 - 4.6e-53 179.0 0.1 5.7e-53 178.7 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 AJW71714.1 - 7e-05 22.5 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 2 DeoR C terminal sensor domain Yqai PF09466.5 AJW71714.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein Yqai PCMT PF01135.14 AJW71715.1 - 1.6e-63 214.0 0.0 2e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AJW71715.1 - 2.3e-11 43.4 0.1 4.8e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW71715.1 - 1.6e-10 41.5 0.0 2.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 AJW71715.1 - 2.5e-07 29.9 0.0 3.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 AJW71715.1 - 7.9e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 AJW71715.1 - 1.4e-06 27.8 0.0 3.6e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain GidB PF02527.10 AJW71715.1 - 0.00014 21.0 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.8 AJW71715.1 - 0.00043 19.4 0.0 0.00061 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 AJW71715.1 - 0.0025 16.9 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Fibrillarin PF01269.12 AJW71715.1 - 0.0034 16.3 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin Methyltransf_26 PF13659.1 AJW71715.1 - 0.0034 17.4 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJW71715.1 - 0.0053 17.2 0.0 0.0096 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW71715.1 - 0.06 13.0 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 AJW71715.1 - 0.066 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 AJW71715.1 - 0.096 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SATase_N PF06426.9 AJW71716.1 - 0.46 10.7 2.6 28 5.0 0.0 3.1 2 1 1 3 3 3 0 Serine acetyltransferase, N-terminal Amidohydro_4 PF13147.1 AJW71717.1 - 4e-20 72.9 0.0 3.5e-19 69.9 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 AJW71717.1 - 3.5e-09 36.7 2.0 1.6e-07 31.3 1.4 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AJW71717.1 - 9.8e-09 34.9 3.4 2.1e-08 33.8 1.6 2.2 2 0 0 2 2 2 1 Amidohydrolase TatD_DNase PF01026.16 AJW71717.1 - 4.4e-05 22.8 0.5 0.00012 21.4 0.1 1.9 2 1 0 2 2 2 1 TatD related DNase Amidohydro_3 PF07969.6 AJW71717.1 - 0.00028 20.2 0.2 0.011 14.9 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family SecG PF03840.9 AJW71718.1 - 0.81 9.4 5.3 0.49 10.1 1.4 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit zinc_ribbon_2 PF13240.1 AJW71719.1 - 1.7e-09 36.8 11.2 2.8e-07 29.8 3.4 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 AJW71719.1 - 1.6e-08 33.4 3.3 2.7e-08 32.7 2.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AJW71719.1 - 3.2e-06 26.8 2.0 4.8e-06 26.2 1.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 AJW71719.1 - 6.1e-05 22.6 2.8 0.0003 20.4 2.1 1.9 1 1 1 2 2 2 2 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 AJW71719.1 - 0.00029 20.4 4.7 0.058 13.0 0.2 2.4 2 0 0 2 2 2 2 Nudix N-terminal RNA_POL_M_15KD PF02150.11 AJW71719.1 - 0.0054 16.4 2.8 1.8 8.3 0.1 2.3 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit GFA PF04828.9 AJW71719.1 - 0.044 13.7 3.9 0.96 9.4 0.1 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 AJW71719.1 - 0.049 13.1 5.8 5.4 6.6 4.0 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Prok-RING_1 PF14446.1 AJW71719.1 - 0.058 13.1 1.3 0.081 12.6 0.9 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 AJW71719.1 - 0.13 11.9 1.2 0.19 11.5 0.8 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 AJW71719.1 - 0.14 11.6 4.9 3.2 7.3 0.4 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 AJW71719.1 - 0.42 9.9 3.1 6 6.2 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding NOB1_Zn_bind PF08772.6 AJW71719.1 - 0.42 10.4 7.6 2.4 8.0 0.6 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like YhfH PF14149.1 AJW71719.1 - 0.46 10.3 3.8 5.1 6.9 0.1 2.2 1 1 1 2 2 2 0 YhfH-like protein zf-tcix PF14952.1 AJW71719.1 - 1.1 8.5 3.9 2.7 7.4 0.4 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Auto_anti-p27 PF06677.7 AJW71719.1 - 1.2 9.0 4.2 5.4 6.8 0.2 2.2 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.1 AJW71720.1 - 1.1e-06 27.9 2.2 1.7e-06 27.3 1.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 AJW71720.1 - 8.5e-06 24.8 4.9 1.5e-05 24.0 3.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 AJW71720.1 - 9.9e-05 22.0 1.7 0.00015 21.5 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon PAH PF02671.16 AJW71720.1 - 0.00097 18.7 0.2 0.0019 17.7 0.1 1.5 1 0 0 1 1 1 1 Paired amphipathic helix repeat zf-NADH-PPase PF09297.6 AJW71720.1 - 0.82 9.2 4.3 34 4.0 3.0 2.3 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 AJW71720.1 - 1.2 8.8 5.2 5.5 6.7 0.5 2.2 2 0 0 2 2 2 0 Nudix N-terminal Thioredoxin PF00085.15 AJW71721.1 - 3.9e-31 106.7 0.1 4.4e-31 106.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AJW71721.1 - 5.3e-12 45.6 0.2 8.1e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AJW71721.1 - 7.7e-11 42.1 0.0 2.6e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AJW71721.1 - 8.2e-07 28.9 0.1 1.2e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AJW71721.1 - 4.3e-06 26.3 0.1 5.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 AJW71721.1 - 1.5e-05 24.7 0.1 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 AJW71721.1 - 2.9e-05 23.7 0.0 3.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AJW71721.1 - 5.9e-05 22.6 0.1 8.1e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Redoxin HyaE PF07449.6 AJW71721.1 - 0.00056 19.7 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 AJW71721.1 - 0.0028 17.7 0.1 0.13 12.3 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.1 AJW71721.1 - 0.0035 16.8 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF953 PF06110.6 AJW71721.1 - 0.0051 16.2 0.5 0.015 14.7 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_6 PF13848.1 AJW71721.1 - 0.033 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 AJW71721.1 - 0.041 14.1 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GLTP PF08718.6 AJW71721.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DSBA PF01323.15 AJW71721.1 - 0.14 11.7 0.0 2.2 7.7 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DZR PF12773.2 AJW71722.1 - 1.2e-06 28.2 8.8 0.00044 20.0 1.7 2.4 2 0 0 2 2 2 2 Double zinc ribbon PRC PF05239.11 AJW71722.1 - 2e-05 24.3 0.4 3.9e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 PRC-barrel domain zf-ribbon_3 PF13248.1 AJW71722.1 - 2.3e-05 23.4 7.2 2.3e-05 23.4 5.0 2.8 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AJW71722.1 - 8.9e-05 21.8 8.9 8.9e-05 21.8 6.1 2.7 3 0 0 3 3 3 1 zinc-ribbon domain DUF3279 PF11682.3 AJW71722.1 - 0.026 14.0 1.5 8.1 6.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) Cript PF10235.4 AJW71722.1 - 0.14 12.5 2.0 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT RRN7 PF11781.3 AJW71722.1 - 0.22 11.0 11.5 3.2 7.3 2.2 3.4 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-B_box PF00643.19 AJW71722.1 - 0.24 11.3 9.6 1.4 8.8 0.5 3.1 3 0 0 3 3 3 0 B-box zinc finger A2L_zn_ribbon PF08792.5 AJW71722.1 - 0.24 10.8 0.1 0.24 10.8 0.1 4.1 3 1 0 3 3 3 0 A2L zinc ribbon domain zf-AD PF07776.10 AJW71722.1 - 0.5 10.3 0.1 0.5 10.3 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Prim_Zn_Ribbon PF08273.7 AJW71722.1 - 3.1 7.9 13.1 13 5.9 0.0 4.2 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase GFA PF04828.9 AJW71722.1 - 5.4 7.0 11.3 9.1 6.3 0.1 3.6 2 2 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Peptidase_S24 PF00717.18 AJW71723.1 - 7.2e-08 31.9 2.2 2e-07 30.5 0.3 2.2 2 0 0 2 2 2 1 Peptidase S24-like MscL PF01741.13 AJW71723.1 - 0.0036 17.4 0.9 0.0062 16.6 0.0 1.9 2 0 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL HpaB_N PF11794.3 AJW71724.1 - 4.5e-89 298.3 0.0 1.1e-88 297.0 0.0 1.6 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.8 AJW71724.1 - 2.9e-72 241.8 0.1 3.9e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Bt_P21 PF05560.6 AJW71724.1 - 0.054 12.8 0.2 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein ATP-grasp_5 PF13549.1 AJW71725.1 - 3.1e-78 262.0 0.8 7.2e-78 260.8 0.5 1.7 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 AJW71725.1 - 2.9e-52 175.9 0.7 7.9e-52 174.5 0.5 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AJW71725.1 - 5.4e-24 84.6 1.2 1.6e-23 83.0 0.1 2.4 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.14 AJW71725.1 - 8.7e-10 38.9 3.1 6.5e-09 36.1 0.5 2.8 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 AJW71725.1 - 5.8e-06 25.8 2.7 1.3e-05 24.6 1.9 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AJW71725.1 - 0.00023 20.9 0.0 0.00057 19.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AJW71725.1 - 0.00072 18.8 0.2 0.0016 17.7 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 AJW71725.1 - 0.041 13.2 0.3 0.19 11.0 0.2 2.1 1 1 0 1 1 1 0 ATP-grasp domain RNase_H PF00075.19 AJW71726.1 - 5.1e-16 59.2 0.0 5.9e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 AJW71726.1 - 1.4e-11 44.0 0.1 1.9e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like Hex_IIIa PF02455.11 AJW71726.1 - 0.013 14.1 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) VKG_Carbox PF05090.9 AJW71726.1 - 0.058 12.2 0.1 0.07 11.9 0.1 1.0 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF3493 PF11998.3 AJW71727.1 - 0.0051 16.6 1.3 0.095 12.6 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3493) DUF3270 PF11674.3 AJW71727.1 - 0.016 15.1 3.0 0.35 10.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) DUF443 PF04276.7 AJW71727.1 - 0.034 13.5 6.4 0.045 13.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Thia_YuaJ PF09515.5 AJW71727.1 - 0.043 13.5 6.4 0.062 13.0 4.5 1.2 1 0 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) MARVEL PF01284.18 AJW71727.1 - 0.075 12.8 4.3 5 6.9 1.9 2.1 2 0 0 2 2 2 0 Membrane-associating domain DUF3278 PF11683.3 AJW71727.1 - 0.15 12.0 3.6 0.095 12.6 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) Trep_Strep PF09605.5 AJW71727.1 - 0.63 9.6 8.3 0.083 12.5 1.6 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) MnhB PF04039.8 AJW71727.1 - 0.96 9.5 4.7 1 9.4 0.4 2.0 1 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF3784 PF12650.2 AJW71727.1 - 0.96 9.4 9.7 1.6 8.7 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) SPC25 PF06703.6 AJW71727.1 - 1.7 8.2 6.8 0.14 11.6 0.8 1.7 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Flavi_NS2B PF01002.14 AJW71728.1 - 0.08 12.5 1.4 0.12 11.9 1.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Tmemb_14 PF03647.8 AJW71728.1 - 0.089 13.1 0.7 0.089 13.1 0.5 1.8 2 0 0 2 2 2 0 Transmembrane proteins 14C HTH_5 PF01022.15 AJW71729.1 - 1.2e-08 34.5 0.1 5.7e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 AJW71729.1 - 3.1e-06 26.9 0.0 5.8e-06 26.0 0.0 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.14 AJW71729.1 - 0.0002 20.9 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 AJW71729.1 - 0.0003 20.5 0.1 0.00042 20.0 0.1 1.1 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_45 PF14947.1 AJW71729.1 - 0.00039 20.1 0.5 0.00048 19.8 0.4 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.1 AJW71729.1 - 0.00048 19.4 0.2 0.00068 18.9 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 AJW71729.1 - 0.0031 17.1 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_12 PF08461.5 AJW71729.1 - 0.0033 17.1 0.1 0.0053 16.4 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_34 PF13601.1 AJW71729.1 - 0.0049 16.8 0.2 0.0088 16.0 0.0 1.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain Rrf2 PF02082.15 AJW71729.1 - 0.037 14.1 0.1 0.061 13.4 0.1 1.5 1 1 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 AJW71729.1 - 0.039 13.6 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 MarR family DUF4423 PF14394.1 AJW71729.1 - 0.05 13.1 0.5 0.18 11.3 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4423) MarR PF01047.17 AJW71729.1 - 0.052 13.2 0.1 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_10 PF04967.7 AJW71729.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Phage_rep_O PF04492.8 AJW71729.1 - 0.11 12.7 0.1 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication protein O Lipid_bd PF12888.2 AJW71729.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipid-binding putative hydrolase Radical_SAM PF04055.16 AJW71730.1 - 2e-15 57.3 0.1 4e-15 56.3 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 AJW71730.1 - 0.00038 20.4 0.1 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Ammonium_transp PF00909.16 AJW71733.1 - 0.006 15.0 7.1 0.006 15.0 4.9 1.7 1 1 0 1 1 1 1 Ammonium Transporter Family Caveolin PF01146.12 AJW71733.1 - 1.1 8.8 4.4 0.66 9.5 1.6 1.7 1 1 1 2 2 2 0 Caveolin FtsX PF02687.16 AJW71733.1 - 5.7 6.7 16.8 0.026 14.2 4.5 2.1 2 1 0 2 2 2 0 FtsX-like permease family Acetyltransf_1 PF00583.19 AJW71734.1 - 7e-15 54.8 0.0 9.6e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AJW71734.1 - 1.8e-10 40.8 0.2 2.5e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AJW71734.1 - 1.3e-08 34.8 0.1 1.7e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AJW71734.1 - 6.8e-08 32.6 0.0 7.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AJW71734.1 - 0.00034 20.5 0.0 0.00057 19.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AJW71734.1 - 0.0021 17.7 0.0 0.0048 16.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 AJW71734.1 - 0.0046 16.5 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AJW71734.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Staphostatin_A PF09022.5 AJW71734.1 - 0.052 13.3 0.8 0.09 12.6 0.6 1.4 1 0 0 1 1 1 0 Staphostatin A Response_reg PF00072.19 AJW71735.1 - 4e-24 84.7 0.3 4.5e-24 84.6 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.6 AJW71735.1 - 0.0031 17.6 0.1 0.0036 17.4 0.1 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Glu_syn_central PF04898.9 AJW71735.1 - 0.059 12.6 0.2 0.091 12.0 0.1 1.3 1 1 0 1 1 1 0 Glutamate synthase central domain HATPase_c PF02518.21 AJW71736.1 - 4.5e-21 74.6 0.1 8.3e-21 73.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AJW71736.1 - 6.6e-09 35.6 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 AJW71736.1 - 6.3e-07 29.0 0.1 1.6e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 AJW71736.1 - 0.00016 21.3 1.3 0.0003 20.4 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPC25 PF06703.6 AJW71736.1 - 0.14 11.7 1.0 0.48 10.0 0.1 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1510 PF07423.6 AJW71736.1 - 3.5 6.9 5.7 0.66 9.3 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4446 PF14584.1 AJW71736.1 - 8.6 6.1 9.6 0.14 11.9 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Methyltransf_11 PF08241.7 AJW71737.1 - 1.6e-16 60.6 0.0 2.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW71737.1 - 2.5e-14 53.4 0.0 4.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW71737.1 - 1e-13 51.1 0.3 1.3e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW71737.1 - 2.4e-09 37.1 0.1 2.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW71737.1 - 2.9e-09 37.3 0.0 6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW71737.1 - 1.7e-06 28.5 0.0 2.3e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AJW71737.1 - 2.2e-06 27.6 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AJW71737.1 - 9.2e-06 24.9 0.1 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 AJW71737.1 - 0.00014 21.0 0.6 0.00033 19.8 0.4 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 AJW71737.1 - 0.0012 18.2 0.0 0.0052 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 AJW71737.1 - 0.0028 17.0 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 AJW71737.1 - 0.019 14.2 0.7 6 6.1 0.0 3.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PSI_PsaH PF03244.9 AJW71737.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Aminotran_4 PF01063.14 AJW71738.1 - 2e-44 151.7 0.0 2.3e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV AA_kinase PF00696.23 AJW71740.1 - 2.6e-28 99.1 0.6 6.4e-28 97.9 0.4 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 AJW71740.1 - 0.023 14.1 0.8 0.023 14.1 0.6 2.2 2 0 0 2 2 2 0 ACT domain YajC PF02699.10 AJW71740.1 - 0.078 12.6 0.4 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit Glyco_trans_1_3 PF13528.1 AJW71741.1 - 6.8e-18 64.9 0.0 9.8e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 AJW71741.1 - 4.4e-12 45.9 0.1 1e-11 44.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.1 AJW71741.1 - 0.0001 22.4 0.0 0.00066 19.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 TEBP_beta PF07404.6 AJW71741.1 - 0.094 11.8 0.1 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Phage_integrase PF00589.17 AJW71742.1 - 0.024 14.3 0.0 0.17 11.5 0.0 2.2 1 1 0 1 1 1 0 Phage integrase family DUF217 PF02697.9 AJW71743.1 - 0.015 15.5 0.2 0.016 15.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized ACR, COG1753 HNH PF01844.18 AJW71745.1 - 0.0044 16.8 6.1 0.0083 15.9 4.2 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF3072 PF11272.3 AJW71745.1 - 0.089 12.4 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) HNH_4 PF13395.1 AJW71745.1 - 5.1 6.8 7.8 0.14 11.7 0.7 2.0 2 0 0 2 2 2 0 HNH endonuclease DUF2254 PF10011.4 AJW71746.1 - 0.029 12.8 0.6 0.029 12.8 0.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) YlaC PF10777.4 AJW71746.1 - 3.5 7.1 8.3 8 6.0 0.9 2.9 3 1 1 4 4 4 0 Inner membrane protein YlaC PHD PF00628.24 AJW71747.1 - 0.036 13.7 1.1 0.064 12.9 0.8 1.4 1 0 0 1 1 1 0 PHD-finger NUMOD1 PF07453.8 AJW71747.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 NUMOD1 domain DUF1887 PF09002.6 AJW71747.1 - 0.12 10.7 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) TrmB PF01978.14 AJW71749.1 - 0.025 14.2 0.4 0.35 10.6 0.0 2.1 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB EAP30 PF04157.11 AJW71749.1 - 0.036 13.2 0.1 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family FBD PF08387.5 AJW71749.1 - 0.038 13.4 0.2 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 FBD PadR PF03551.9 AJW71749.1 - 0.043 13.5 0.1 0.083 12.6 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family DUF294_C PF10335.4 AJW71749.1 - 0.045 13.4 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Ribosomal_S19e PF01090.14 AJW71749.1 - 0.062 12.7 0.2 0.077 12.4 0.1 1.3 1 1 0 1 1 1 0 Ribosomal protein S19e TfuA PF07812.7 AJW71750.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 TfuA-like protein Multi_ubiq PF14452.1 AJW71751.1 - 2.5e-15 56.1 0.1 2.9e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Multiubiquitin CAP PF00188.21 AJW71755.1 - 4.7e-20 72.3 0.6 4.7e-20 72.3 0.4 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family THP2 PF09432.5 AJW71755.1 - 0.0063 16.3 1.4 2.4 8.0 0.1 2.3 1 1 1 2 2 2 2 Tho complex subunit THP2 A2L_zn_ribbon PF08792.5 AJW71755.1 - 0.023 14.1 1.4 0.049 13.0 0.9 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF2232 PF09991.4 AJW71755.1 - 0.038 12.9 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Prominin PF05478.6 AJW71755.1 - 0.045 11.3 0.0 0.056 10.9 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF948 PF06103.6 AJW71755.1 - 0.076 12.8 0.5 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) 2_5_RNA_ligase2 PF13563.1 AJW71756.1 - 1.4e-17 63.8 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 AJW71756.1 - 0.011 15.7 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase A2M_N PF01835.14 AJW71758.1 - 9.7e-06 25.7 0.1 7.8e-05 22.8 0.0 2.3 1 1 0 2 2 2 1 MG2 domain Copper-bind PF00127.15 AJW71758.1 - 5.3e-05 23.3 0.2 0.18 12.0 0.0 2.9 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 AJW71758.1 - 5.5e-05 22.9 0.0 0.074 12.9 0.0 3.6 3 0 0 3 3 3 1 Cupredoxin-like domain A2M_N_2 PF07703.9 AJW71758.1 - 0.0053 16.5 0.4 0.016 15.0 0.1 1.8 2 0 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region CopC PF04234.7 AJW71758.1 - 0.076 13.6 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 CopC domain A2M_N PF01835.14 AJW71759.1 - 1.7e-10 41.0 0.2 3.4e-10 40.0 0.1 1.5 2 0 0 2 2 2 1 MG2 domain FlgD_ig PF13860.1 AJW71759.1 - 0.032 13.9 0.8 0.068 12.9 0.5 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain PAS_7 PF12860.2 AJW71759.1 - 0.033 14.2 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold Response_reg PF00072.19 AJW71760.1 - 3.4e-29 101.1 0.2 3.8e-29 100.9 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF1307 PF06998.6 AJW71760.1 - 0.0071 16.3 0.6 0.0092 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1307) Response_reg PF00072.19 AJW71761.1 - 4.7e-18 65.2 0.1 5.7e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Phage_30_3 PF08010.6 AJW71761.1 - 0.06 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Response_reg PF00072.19 AJW71762.1 - 1.7e-20 73.0 0.0 1.9e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 AJW71762.1 - 0.0009 19.0 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 B12 binding domain DUF2608 PF11019.3 AJW71762.1 - 0.035 13.0 0.1 0.076 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) 2-Hacid_dh_C PF02826.14 AJW71762.1 - 0.14 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HisKA PF00512.20 AJW71763.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF4600 PF15372.1 AJW71763.1 - 0.044 13.9 0.2 0.048 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Polyketide_cyc2 PF10604.4 AJW71765.1 - 1.5e-07 31.7 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 AJW71765.1 - 3.5e-07 30.3 0.0 5.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.15 AJW71765.1 - 1.9e-06 27.8 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Col_cuticle_N PF01484.12 AJW71766.1 - 0.25 11.0 8.2 0.24 11.1 0.9 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain COX15-CtaA PF02628.10 AJW71767.1 - 2.1e-24 85.9 10.5 2.7e-24 85.5 7.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF4418 PF14387.1 AJW71767.1 - 3.1 7.5 9.1 0.29 10.8 0.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4418) Copper-bind PF00127.15 AJW71768.1 - 1.3e-14 54.2 0.2 9.9e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.10 AJW71768.1 - 9.6e-14 51.1 0.7 9.3e-06 25.3 0.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu_bind_like PF02298.12 AJW71768.1 - 9.5e-08 31.7 0.2 0.023 14.4 0.1 3.0 2 1 0 2 2 2 2 Plastocyanin-like domain Cupredoxin_1 PF13473.1 AJW71768.1 - 2.3e-07 30.6 0.0 0.0082 16.0 0.0 2.6 2 0 0 2 2 2 2 Cupredoxin-like domain SoxE PF06525.6 AJW71768.1 - 7.8e-07 28.5 1.2 0.03 13.6 0.0 2.9 2 1 0 2 2 2 2 Sulfocyanin (SoxE) Cu-oxidase_2 PF07731.9 AJW71768.1 - 1.2e-06 28.0 0.0 0.046 13.2 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase COX2 PF00116.15 AJW71768.1 - 0.0052 16.5 0.1 1.6 8.5 0.0 2.8 2 1 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain CHU_C PF13585.1 AJW71768.1 - 0.026 14.3 0.3 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of CHU protein family PPC PF04151.10 AJW71768.1 - 5 8.1 12.2 0.66 10.9 1.2 3.2 2 2 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain COX1 PF00115.15 AJW71769.1 - 1.5e-141 472.1 58.8 1.9e-141 471.7 40.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.15 AJW71770.1 - 3.9e-21 75.0 1.0 6e-19 68.0 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.1 AJW71770.1 - 6.4e-05 22.7 0.0 7.5e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Cupredoxin-like domain BPD_transp_2 PF02653.11 AJW71771.1 - 0.055 12.4 0.5 0.072 12.0 0.3 1.3 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF2567 PF10821.3 AJW71771.1 - 0.48 9.9 4.0 0.85 9.1 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2567) His_Phos_1 PF00300.17 AJW71772.1 - 3.6e-34 118.1 0.0 4.2e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lipase_GDSL_3 PF14606.1 AJW71772.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CRM1_C PF08767.6 AJW71772.1 - 0.056 12.3 0.1 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal F420_oxidored PF03807.12 AJW71773.1 - 2e-15 56.9 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 AJW71773.1 - 0.036 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 AJW71773.1 - 0.046 13.5 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.12 AJW71773.1 - 0.062 12.1 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase DapB_N PF01113.15 AJW71773.1 - 0.077 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 AJW71773.1 - 0.11 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF308 PF03729.8 AJW71774.1 - 0.00062 19.6 1.2 0.17 11.9 0.1 2.2 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) MerC PF03203.9 AJW71774.1 - 0.12 12.7 0.2 0.27 11.5 0.2 1.6 1 1 1 2 2 2 0 MerC mercury resistance protein DctQ PF04290.7 AJW71774.1 - 0.18 11.5 1.3 0.27 10.9 0.9 1.3 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Pyridox_oxidase PF01243.15 AJW71775.1 - 1.3e-15 57.1 0.0 2.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AJW71775.1 - 1e-10 41.6 0.0 1.3e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PPTA PF01239.17 AJW71775.1 - 0.025 13.9 0.0 0.075 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Aminotran_1_2 PF00155.16 AJW71776.1 - 1e-59 202.3 0.0 1.2e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AJW71776.1 - 3.9e-08 32.4 0.0 7.9e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AJW71776.1 - 1.4e-06 27.5 0.0 2.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AJW71776.1 - 0.0034 16.5 0.0 0.0067 15.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AJW71776.1 - 0.0055 15.0 0.0 0.0079 14.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 AJW71776.1 - 0.024 13.1 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase HRDC PF00570.18 AJW71776.1 - 0.047 13.4 0.2 19 5.0 0.0 3.3 3 1 1 4 4 4 0 HRDC domain DUF2653 PF10850.3 AJW71778.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) adh_short_C2 PF13561.1 AJW71779.1 - 2e-07 31.0 0.0 6.1e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AJW71779.1 - 2.6e-06 27.4 0.0 0.018 14.9 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 AJW71779.1 - 0.0027 16.6 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AJW71779.1 - 0.0048 16.3 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AJW71779.1 - 0.083 12.8 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 AJW71779.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 AJW71780.1 - 2.2e-08 34.4 0.0 8.6e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW71780.1 - 6.1e-08 32.5 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW71780.1 - 0.092 13.1 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AJW71780.1 - 0.11 13.0 0.1 0.37 11.2 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AJW71780.1 - 0.11 12.1 0.1 0.48 9.9 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain GRAS PF03514.9 AJW71780.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 GRAS domain family Polysacc_deac_1 PF01522.16 AJW71781.1 - 5.7e-16 58.2 0.0 9.4e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Hexokinase_1 PF00349.16 AJW71781.1 - 0.078 12.3 0.8 1.1 8.5 0.1 2.8 2 1 2 4 4 4 0 Hexokinase Sulfotransfer_1 PF00685.22 AJW71782.1 - 4.3e-16 58.9 0.3 5.4e-16 58.6 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 AJW71782.1 - 1.9e-06 28.9 0.0 3.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 AJW71782.1 - 0.00052 19.7 1.6 0.0015 18.2 1.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family DUF4051 PF13260.1 AJW71782.1 - 0.15 11.3 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF59 PF01883.14 AJW71783.1 - 4.5e-16 58.5 0.3 9.6e-16 57.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 PqqD PF05402.7 AJW71783.1 - 4.9e-09 36.0 0.1 8.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) MukE PF04288.8 AJW71783.1 - 0.057 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 MukE-like family IF-2B PF01008.12 AJW71785.1 - 1e-86 290.4 2.0 1.2e-86 290.1 1.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RRM_1 PF00076.17 AJW71785.1 - 0.0027 17.3 0.0 0.029 14.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serine_rich PF08824.5 AJW71785.1 - 0.0073 16.0 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Serine rich protein interaction domain YokU PF14122.1 AJW71785.1 - 0.08 12.6 0.5 5 6.9 0.1 2.5 2 1 0 2 2 2 0 YokU-like protein bact-PGI_C PF10432.4 AJW71786.1 - 1.1e-34 119.4 0.0 2.6e-34 118.1 0.0 1.6 2 0 0 2 2 2 1 Bacterial phospho-glucose isomerase C-terminal region SIS PF01380.17 AJW71786.1 - 6.6e-09 35.4 0.1 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 SIS domain Tn7_Tnp_TnsA_N PF08722.6 AJW71786.1 - 0.015 15.3 0.3 0.031 14.2 0.2 1.6 1 0 0 1 1 1 0 TnsA endonuclease N terminal PGI PF00342.14 AJW71786.1 - 0.036 12.5 0.1 0.055 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucose isomerase SIS_2 PF13580.1 AJW71786.1 - 0.082 12.6 0.2 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 SIS domain Epimerase PF01370.16 AJW71787.1 - 2.7e-59 200.4 0.1 3.3e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJW71787.1 - 1.6e-33 115.6 3.0 2e-33 115.2 2.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJW71787.1 - 9.8e-27 93.5 0.0 1.2e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AJW71787.1 - 2.6e-22 79.0 8.2 2.3e-21 75.9 5.7 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AJW71787.1 - 2.5e-21 75.7 0.6 9e-20 70.6 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AJW71787.1 - 5.4e-18 65.6 0.0 7.2e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AJW71787.1 - 6.4e-11 41.9 3.8 1e-10 41.2 2.7 1.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 AJW71787.1 - 5.5e-06 26.3 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AJW71787.1 - 3.9e-05 23.3 0.0 7.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase_Csub PF13950.1 AJW71787.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit SpoU_sub_bind PF08032.7 AJW71787.1 - 0.0061 16.6 3.7 0.72 10.0 0.1 2.9 3 0 0 3 3 3 2 RNA 2'-O ribose methyltransferase substrate binding DapH_N PF08503.5 AJW71787.1 - 0.0088 16.1 7.3 2.1 8.5 0.2 3.4 2 1 1 3 3 3 2 Tetrahydrodipicolinate succinyltransferase N-terminal DapB_N PF01113.15 AJW71787.1 - 0.016 15.0 0.3 0.06 13.2 0.2 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 AJW71787.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1506 PF07405.6 AJW71787.1 - 0.028 14.3 0.3 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) CTP_transf_3 PF02348.14 AJW71788.1 - 1.3e-28 100.0 1.0 1.6e-28 99.8 0.7 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Agenet PF05641.7 AJW71788.1 - 0.031 14.4 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Agenet domain DegT_DnrJ_EryC1 PF01041.12 AJW71789.1 - 2.8e-94 316.1 0.0 3.2e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AJW71789.1 - 7e-09 35.2 0.0 1.5e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 AJW71789.1 - 1.7e-08 33.3 0.1 2.1e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_1_2 PF00155.16 AJW71789.1 - 2e-08 33.5 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AJW71789.1 - 4.4e-06 25.2 0.0 8.1e-06 24.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NeuB PF03102.9 AJW71790.1 - 2.6e-36 125.0 0.6 5.6e-36 123.8 0.4 1.5 1 1 0 1 1 1 1 NeuB family AP_endonuc_2 PF01261.19 AJW71790.1 - 0.062 12.5 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acetyltransf_3 PF13302.1 AJW71791.1 - 2.7e-11 43.8 0.0 3.1e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AJW71791.1 - 8.4e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AJW71791.1 - 5.5e-06 26.4 0.2 8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AJW71791.1 - 3.1e-05 23.8 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AJW71791.1 - 0.00025 21.0 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AJW71791.1 - 0.00036 20.2 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AJW71791.1 - 0.0043 17.1 0.0 0.0049 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Polysacc_synt_2 PF02719.10 AJW71792.1 - 1.1e-95 320.0 0.1 1.3e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 AJW71792.1 - 6.7e-28 97.7 0.2 1.2e-26 93.6 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJW71792.1 - 1.5e-24 86.2 0.1 4.4e-22 78.0 0.0 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJW71792.1 - 4.2e-15 55.4 0.0 2.6e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 AJW71792.1 - 3.8e-11 42.3 0.9 9.6e-09 34.5 0.2 2.7 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 AJW71792.1 - 1.8e-09 37.8 0.0 2.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AJW71792.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 AJW71792.1 - 8.4e-06 25.1 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 AJW71792.1 - 0.00037 20.1 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 AJW71792.1 - 0.00083 19.6 0.0 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AJW71792.1 - 0.012 15.7 0.6 0.033 14.2 0.0 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 AJW71792.1 - 0.018 15.4 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 AJW71792.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 AJW71792.1 - 0.14 11.1 0.0 0.39 9.6 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase Zn_ribbon_2 PF12674.2 AJW71793.1 - 0.017 15.4 2.2 0.1 12.9 0.8 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain Glyphos_transf PF04464.9 AJW71794.1 - 5.9e-10 38.4 7.3 1.3e-09 37.3 5.1 1.6 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Capsule_synth PF05159.9 AJW71794.1 - 0.00042 19.8 0.3 0.0073 15.8 0.2 2.3 1 1 0 1 1 1 1 Capsule polysaccharide biosynthesis protein Epimerase_2 PF02350.14 AJW71794.1 - 0.00099 17.9 0.2 0.0016 17.3 0.1 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Methyltransf_31 PF13847.1 AJW71795.1 - 2.5e-22 79.0 2.7 5.9e-22 77.8 1.6 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AJW71795.1 - 3.2e-15 56.4 0.1 7.2e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AJW71795.1 - 3e-14 53.5 0.0 7.8e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AJW71795.1 - 1.6e-12 47.7 0.0 3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AJW71795.1 - 2.8e-12 46.8 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AJW71795.1 - 1.6e-11 44.1 0.0 3.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AJW71795.1 - 5.6e-10 38.4 0.1 8.9e-10 37.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 AJW71795.1 - 6.2e-08 31.9 0.1 1.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AJW71795.1 - 7.4e-07 29.2 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AJW71795.1 - 1.3e-06 27.9 0.1 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 AJW71795.1 - 1.4e-05 24.0 0.1 3.3e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 DREV methyltransferase CheR PF01739.13 AJW71795.1 - 1.7e-05 24.2 0.3 0.00022 20.5 0.1 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain GidB PF02527.10 AJW71795.1 - 0.00093 18.3 0.4 0.0016 17.5 0.3 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.13 AJW71795.1 - 0.0017 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 AJW71795.1 - 0.0026 16.9 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 AJW71795.1 - 0.0049 16.1 0.0 0.0098 15.2 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 NodS PF05401.6 AJW71795.1 - 0.0071 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Rsm22 PF09243.5 AJW71795.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_2 PF00891.13 AJW71795.1 - 0.029 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 AJW71795.1 - 0.038 13.6 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 AJW71795.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) NAD_synthase PF02540.12 AJW71796.1 - 6.3e-58 195.5 1.9 6.9e-33 113.5 0.2 2.0 1 1 1 2 2 2 2 NAD synthase QueC PF06508.8 AJW71796.1 - 4.1e-06 26.2 0.3 0.0001 21.6 0.0 2.8 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AJW71796.1 - 1.7e-05 23.5 0.1 4.4e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 AJW71796.1 - 0.031 13.7 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase DUF416 PF04222.7 AJW71796.1 - 0.04 13.0 0.4 0.13 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Glycos_transf_2 PF00535.21 AJW71797.1 - 2.2e-28 99.0 0.0 4e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AJW71797.1 - 3.6e-16 59.6 0.0 4.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AJW71797.1 - 0.0008 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 AJW71797.1 - 0.00093 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.1 AJW71797.1 - 0.01 15.0 0.0 4.9 6.3 0.0 2.9 2 1 1 3 3 3 0 Glycosyltransferase like family ACPS PF01648.15 AJW71798.1 - 7.1e-15 54.8 0.0 9.3e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NTPase_I-T PF01931.13 AJW71798.1 - 0.058 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 3-dmu-9_3-mt PF06983.8 AJW71798.1 - 0.062 13.6 1.5 0.081 13.2 0.9 1.3 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase AMP-binding PF00501.23 AJW71800.1 - 6.4e-72 242.2 0.0 7.4e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AJW71800.1 - 2.2e-08 34.9 0.0 3.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 AJW71800.1 - 0.03 12.8 0.0 0.76 8.2 0.0 2.3 2 1 0 2 2 2 0 GH3 auxin-responsive promoter LpxD PF04613.9 AJW71800.1 - 0.037 13.5 0.0 1.3 8.5 0.0 2.8 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep PF00132.19 AJW71801.1 - 3.1e-11 42.2 19.3 5e-06 25.7 5.8 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AJW71801.1 - 9.9e-10 37.8 13.4 0.0013 18.2 6.7 3.6 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF2613 PF11021.3 AJW71801.1 - 0.29 10.8 2.5 0.5 10.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Cpn60_TCP1 PF00118.19 AJW71802.1 - 0.067 11.8 0.5 0.094 11.3 0.3 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family MBOAT PF03062.14 AJW71803.1 - 1.4e-52 178.8 9.5 1.4e-52 178.8 6.6 3.1 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AJW71803.1 - 2.2e-05 24.4 1.0 2.2e-05 24.4 0.7 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family dTDP_sugar_isom PF00908.12 AJW71804.1 - 4.3e-68 228.1 0.1 4.8e-68 227.9 0.1 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Epimerase PF01370.16 AJW71805.1 - 3.3e-59 200.2 0.0 4e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJW71805.1 - 1.8e-19 69.5 0.0 2.2e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJW71805.1 - 4.9e-19 68.3 0.0 6.3e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 AJW71805.1 - 1.3e-16 60.2 0.0 1.2e-14 53.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 AJW71805.1 - 3.5e-15 55.6 0.1 1.9e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AJW71805.1 - 0.00017 21.6 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 AJW71805.1 - 0.0029 16.6 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase_Csub PF13950.1 AJW71805.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NmrA PF05368.8 AJW71805.1 - 0.081 12.1 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 AJW71805.1 - 0.089 12.7 0.1 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Glyco_trans_1_3 PF13528.1 AJW71805.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 RmlD_sub_bind PF04321.12 AJW71806.1 - 6.6e-68 228.6 0.0 7.4e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AJW71806.1 - 4.3e-23 81.9 0.0 7.9e-23 81.1 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AJW71806.1 - 2.2e-09 36.6 0.0 2.4e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 AJW71806.1 - 8.3e-09 34.7 2.6 3.6e-07 29.3 1.8 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AJW71806.1 - 3.1e-07 29.3 0.1 4.9e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 AJW71806.1 - 8.4e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 AJW71806.1 - 0.1 12.5 0.1 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Glycos_transf_2 PF00535.21 AJW71807.1 - 2.9e-23 82.3 0.1 4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AJW71807.1 - 0.00011 22.1 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RseC_MucC PF04246.7 AJW71807.1 - 0.064 12.8 0.4 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Capsule_synth PF05159.9 AJW71808.1 - 3.2e-05 23.5 0.1 7.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein Sec-ASP3 PF15432.1 AJW71808.1 - 1.5 8.7 9.0 1.2 9.1 0.8 3.1 3 0 0 3 3 3 0 Accessory Sec secretory system ASP3 Polysacc_synt_3 PF13440.1 AJW71809.1 - 1.5e-08 34.4 39.5 3.1e-05 23.5 20.0 2.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.1 AJW71809.1 - 1.7e-07 31.1 3.5 1.7e-07 31.1 2.4 4.8 2 1 2 4 4 4 3 Polysaccharide biosynthesis C-terminal domain Methyltransf_24 PF13578.1 AJW71810.1 - 2e-19 70.3 0.0 2.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AJW71810.1 - 4.2e-08 32.9 0.0 7.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 AJW71810.1 - 1.5e-07 30.6 0.0 2.5e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase CmcI PF04989.7 AJW71810.1 - 3.5e-07 29.7 0.1 1.3e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.2 AJW71810.1 - 3.8e-07 30.6 0.0 5.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AJW71810.1 - 0.046 13.2 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 AJW71810.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YfhO PF09586.5 AJW71811.1 - 0.0003 18.9 1.8 0.00032 18.9 1.2 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Glyco_transf_22 PF03901.12 AJW71811.1 - 0.0021 17.1 3.1 0.0027 16.7 2.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Vpu PF00558.14 AJW71811.1 - 0.019 14.4 0.3 0.066 12.7 0.1 1.9 2 0 0 2 2 2 0 Vpu protein MFS_1 PF07690.11 AJW71811.1 - 0.042 12.5 2.6 0.059 12.0 1.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily PrgI PF12666.2 AJW71811.1 - 0.078 13.1 2.8 0.097 12.8 0.5 2.0 1 1 1 2 2 2 0 PrgI family protein DUF202 PF02656.10 AJW71811.1 - 0.16 12.2 0.2 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Wzy_C PF04932.10 AJW71811.1 - 0.16 11.7 4.1 0.35 10.6 0.8 2.2 1 1 1 2 2 2 0 O-Antigen ligase O-antigen_lig PF13425.1 AJW71811.1 - 0.24 11.3 7.8 0.39 10.6 3.8 2.0 1 1 1 2 2 2 0 O-antigen ligase like membrane protein VIT1 PF01988.14 AJW71811.1 - 3.3 7.1 5.4 7.3 6.0 3.8 1.5 1 0 0 1 1 1 0 VIT family DUF2207 PF09972.4 AJW71812.1 - 0.0065 15.1 1.0 0.0074 14.9 0.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4010 PF13194.1 AJW71812.1 - 0.043 13.1 0.3 0.054 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Neur_chan_memb PF02932.11 AJW71812.1 - 0.099 12.5 1.2 0.12 12.2 0.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF805 PF05656.9 AJW71813.1 - 0.00085 19.1 2.9 0.0012 18.6 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DUF2207 PF09972.4 AJW71813.1 - 3.8 5.9 7.2 4.5 5.7 5.0 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) NTP_transferase PF00483.18 AJW71814.1 - 1.3e-54 185.0 0.0 1.7e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 AJW71814.1 - 3.7e-10 38.8 13.3 2.7e-06 26.6 1.7 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AJW71814.1 - 7.3e-10 39.1 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 AJW71814.1 - 3.6e-07 29.6 7.4 6.1e-07 28.8 1.5 3.1 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 AJW71814.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase Capsule_synth PF05159.9 AJW71815.1 - 4.3e-13 49.3 1.9 7.1e-13 48.6 1.3 1.3 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein Glyco_trans_1_4 PF13692.1 AJW71816.1 - 1.1e-14 54.7 0.0 1.8e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AJW71816.1 - 4.6e-06 26.8 0.0 2.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 AJW71816.1 - 0.002 17.5 0.0 0.0064 15.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 BRCT PF00533.21 AJW71816.1 - 0.0029 17.7 0.2 0.0089 16.1 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Glyco_trans_4_2 PF13477.1 AJW71816.1 - 0.017 14.9 0.3 0.077 12.8 0.1 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like GFO_IDH_MocA PF01408.17 AJW71817.1 - 2.2e-22 79.7 0.0 3.4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 AJW71817.1 - 0.014 15.7 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Cupin_2 PF07883.6 AJW71818.1 - 1.4e-07 30.8 0.1 2.3e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AJW71818.1 - 8.4e-05 22.0 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Cupin FdtA PF05523.6 AJW71818.1 - 0.00028 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 WxcM-like, C-terminal Cupin_3 PF05899.7 AJW71818.1 - 0.056 12.8 0.2 1.9 7.9 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF861) ARD PF03079.9 AJW71818.1 - 0.061 13.2 0.1 0.088 12.7 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family 3-HAO PF06052.7 AJW71818.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Epimerase PF01370.16 AJW71819.1 - 1.7e-44 152.0 0.0 2.1e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AJW71819.1 - 2.8e-23 82.2 0.0 3.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 AJW71819.1 - 3.3e-14 52.4 0.5 3.9e-10 39.0 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 AJW71819.1 - 1.6e-12 46.7 0.2 2.6e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 AJW71819.1 - 1.3e-11 43.9 2.4 1.6e-09 37.0 1.7 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AJW71819.1 - 0.00039 20.4 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase_Csub PF13950.1 AJW71819.1 - 0.029 14.2 0.0 0.079 12.9 0.0 1.7 1 1 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit DXP_reductoisom PF02670.11 AJW71819.1 - 0.14 12.6 0.1 28 5.2 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Epimerase PF01370.16 AJW71820.1 - 3e-54 183.9 0.0 3.9e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AJW71820.1 - 3.4e-07 29.4 0.0 6.2e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 AJW71820.1 - 2.5e-05 23.1 0.0 3.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase_Csub PF13950.1 AJW71820.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NmrA PF05368.8 AJW71820.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 AJW71820.1 - 0.015 14.1 0.0 0.038 12.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein BHD_2 PF10404.4 AJW71820.1 - 0.027 14.7 0.0 0.067 13.5 0.0 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 GFO_IDH_MocA PF01408.17 AJW71821.1 - 1.9e-14 54.2 0.0 3.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AJW71821.1 - 1.8e-05 24.5 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IlvN PF07991.7 AJW71821.1 - 0.0064 15.8 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Gp_dh_N PF00044.19 AJW71821.1 - 0.014 15.3 0.1 0.054 13.4 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CoA_binding PF02629.14 AJW71821.1 - 0.033 14.6 0.2 0.074 13.5 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain 2-Hacid_dh_C PF02826.14 AJW71821.1 - 0.066 12.3 0.0 0.43 9.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AJW71821.1 - 0.072 13.3 0.1 0.17 12.1 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 AJW71822.1 - 0.013 15.1 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 AJW71822.1 - 0.016 15.2 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 AJW71822.1 - 0.037 13.3 0.1 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 AJW71822.1 - 0.045 12.9 0.0 0.046 12.8 0.0 1.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 AJW71822.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.1 AJW71823.1 - 7.7e-12 45.4 0.1 1.3e-11 44.7 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AJW71823.1 - 1.6e-07 31.4 0.1 9e-07 28.9 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase CTP_transf_3 PF02348.14 AJW71824.1 - 2.8e-27 95.7 0.0 3.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.2 AJW71824.1 - 0.00068 19.7 0.0 0.00078 19.5 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Polysacc_synt_2 PF02719.10 AJW71825.1 - 4.3e-72 242.5 0.2 5e-72 242.2 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 AJW71825.1 - 7.6e-22 77.9 0.0 7.3e-21 74.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AJW71825.1 - 2.9e-19 68.8 0.1 4.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AJW71825.1 - 6.3e-12 44.9 0.4 1.5e-10 40.4 0.3 2.5 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 AJW71825.1 - 5.2e-08 32.9 0.0 7.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 AJW71825.1 - 3.4e-07 29.4 0.0 9e-06 24.7 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 AJW71825.1 - 2e-05 24.6 0.0 2.8e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AJW71825.1 - 0.0012 18.1 0.1 0.0024 17.1 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family ThiF PF00899.16 AJW71825.1 - 0.0067 16.2 0.0 0.022 14.5 0.0 1.9 1 1 1 2 2 2 1 ThiF family TrkA_N PF02254.13 AJW71825.1 - 0.0078 16.2 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 AJW71825.1 - 0.027 13.4 0.5 0.049 12.6 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase MTS PF05175.9 AJW71825.1 - 0.032 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain 2-Hacid_dh_C PF02826.14 AJW71825.1 - 0.071 12.2 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AJW71825.1 - 0.089 12.8 1.4 0.1 12.6 0.2 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 AJW71825.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Toprim PF01751.17 AJW71825.1 - 0.18 11.8 1.1 0.93 9.5 0.0 2.4 1 1 1 2 2 2 0 Toprim domain NeuB PF03102.9 AJW71826.1 - 4.8e-81 271.4 0.7 7.4e-81 270.8 0.5 1.3 1 0 0 1 1 1 1 NeuB family SAF PF08666.7 AJW71826.1 - 4.9e-08 33.2 0.0 1.6e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 SAF domain SAF_2 PF13144.1 AJW71826.1 - 0.067 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 SAF-like Epimerase_2 PF02350.14 AJW71827.1 - 5.1e-81 272.1 2.0 5.8e-81 271.9 1.4 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase MGDG_synth PF06925.6 AJW71827.1 - 8.5e-05 22.5 0.2 0.013 15.4 0.0 2.6 3 0 0 3 3 3 1 Monogalactosyldiacylglycerol (MGDG) synthase SurE PF01975.12 AJW71827.1 - 0.021 14.1 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Survival protein SurE DUF563 PF04577.9 AJW71827.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Lip_prot_lig_C PF10437.4 AJW71827.1 - 1.2 8.8 7.1 0.23 11.1 0.4 3.0 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus MBOAT PF03062.14 AJW71828.1 - 1.5e-52 178.7 9.2 1.5e-52 178.7 6.4 3.2 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AJW71828.1 - 2.6e-05 24.1 1.9 2.6e-05 24.1 1.3 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family DUF3149 PF11346.3 AJW71828.1 - 0.014 14.9 0.5 0.014 14.9 0.4 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3149) DltD_C PF04914.7 AJW71829.1 - 0.0052 16.6 0.7 0.037 13.8 0.1 2.2 2 0 0 2 2 2 1 DltD C-terminal region Glycos_transf_1 PF00534.15 AJW71830.1 - 1.6e-34 118.7 0.2 2.8e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AJW71830.1 - 1.5e-16 60.8 0.0 3.3e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AJW71830.1 - 2.4e-13 50.1 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 AJW71830.1 - 3e-11 43.4 0.0 5.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 AJW71830.1 - 1.9e-07 31.0 0.9 4.5e-06 26.5 0.3 3.0 3 1 0 3 3 3 1 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.1 AJW71830.1 - 2.9e-07 30.7 0.0 8.6e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 AJW71830.1 - 0.0014 18.1 0.2 0.022 14.2 0.0 2.3 1 1 1 2 2 2 1 Starch synthase catalytic domain Radical_SAM PF04055.16 AJW71831.1 - 4.2e-15 56.2 0.2 4.2e-15 56.2 0.1 2.7 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.1 AJW71831.1 - 9.2e-08 32.1 0.0 9.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 AJW71831.1 - 2.8e-07 30.7 0.0 1e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain TrmB PF01978.14 AJW71832.1 - 4.6e-22 77.4 0.0 1.3e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 AJW71832.1 - 8.1e-06 24.9 0.0 9.8e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.5 AJW71832.1 - 7.6e-05 22.2 0.0 0.00087 18.8 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.1 AJW71832.1 - 0.00022 20.5 0.0 0.00049 19.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 AJW71832.1 - 0.0032 17.1 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 MarR family Penicillinase_R PF03965.11 AJW71832.1 - 0.023 14.7 0.0 0.075 13.1 0.0 1.9 2 0 0 2 2 2 0 Penicillinase repressor HTH_27 PF13463.1 AJW71832.1 - 0.026 14.8 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_9 PF08221.6 AJW71832.1 - 0.057 13.2 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain MarR_2 PF12802.2 AJW71832.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 AJW71832.1 - 0.077 13.1 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator YflT PF11181.3 AJW71832.1 - 0.1 12.7 0.1 16 5.7 0.0 2.7 3 0 0 3 3 3 0 Heat induced stress protein YflT Fe_dep_repr_C PF02742.10 AJW71833.1 - 5e-20 70.9 0.2 5e-20 70.9 0.1 1.6 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.14 AJW71833.1 - 4.4e-15 55.3 0.1 7.2e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.17 AJW71833.1 - 8.2e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 AJW71833.1 - 0.00012 22.1 0.1 0.00025 21.1 0.1 1.6 2 0 0 2 2 1 1 Transcriptional regulator MarR_2 PF12802.2 AJW71833.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 AJW71833.1 - 0.00019 21.6 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 AJW71833.1 - 0.00096 18.8 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 AJW71833.1 - 0.0015 18.3 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_Crp_2 PF13545.1 AJW71833.1 - 0.0023 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_1 PF00126.22 AJW71833.1 - 0.0092 15.7 0.0 0.024 14.3 0.0 1.7 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.15 AJW71833.1 - 0.017 14.7 0.1 0.067 12.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family TFIIE_beta PF02186.10 AJW71833.1 - 0.026 14.4 0.2 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain DUF2250 PF10007.4 AJW71833.1 - 0.046 13.6 0.3 0.071 13.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) ANT PF03374.9 AJW71833.1 - 0.06 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain NLPC_P60 PF00877.14 AJW71833.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 NlpC/P60 family HTH_6 PF01418.12 AJW71833.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_11 PF08279.7 AJW71833.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 HTH domain IF2_N PF04760.10 AJW71833.1 - 0.22 11.2 0.1 0.22 11.2 0.1 2.3 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region DUF2387 PF09526.5 AJW71834.1 - 0.0029 17.5 0.4 0.0032 17.3 0.3 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) UPF0047 PF01894.12 AJW71835.1 - 2e-37 127.6 0.0 2.3e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 eRF1_1 PF03463.10 AJW71837.1 - 4.2e-19 68.4 1.2 7.2e-19 67.6 0.8 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 AJW71837.1 - 2.8e-10 40.6 1.8 3.8e-10 40.2 0.2 2.0 2 1 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 AJW71837.1 - 1.5e-09 38.1 0.3 6.3e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 eRF1 domain 3 CutA1 PF03091.10 AJW71838.1 - 1e-28 98.9 4.3 1.1e-28 98.8 3.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF4227 PF14004.1 AJW71838.1 - 0.073 12.9 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4227) Peptidase_M50 PF02163.17 AJW71839.1 - 2.7e-25 88.4 0.3 1.7e-24 85.8 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M50 PDZ_2 PF13180.1 AJW71839.1 - 1.4e-09 37.7 0.0 2.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 AJW71839.1 - 0.0031 17.6 0.3 0.0082 16.3 0.1 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) ATP_bind_3 PF01171.15 AJW71840.1 - 2.1e-21 76.2 0.0 3.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 AJW71840.1 - 8.6e-05 21.2 0.0 0.00014 20.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.14 AJW71840.1 - 0.00041 20.2 0.0 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 AJW71840.1 - 0.047 14.0 0.1 0.15 12.4 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) OrfB_Zn_ribbon PF07282.6 AJW71840.1 - 0.055 13.1 0.7 0.055 13.1 0.5 3.0 3 1 0 3 3 3 0 Putative transposase DNA-binding domain Acylphosphatase PF00708.13 AJW71842.1 - 6e-28 96.7 0.6 6.5e-28 96.6 0.4 1.0 1 0 0 1 1 1 1 Acylphosphatase LuxE PF04443.7 AJW71842.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE Ribosomal_L2_C PF03947.13 AJW71843.1 - 6.7e-34 116.4 1.7 1.7e-33 115.1 1.3 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AJW71843.1 - 1.9e-08 34.1 0.0 4.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain AAA PF00004.24 AJW71844.1 - 1.1e-99 329.8 0.0 2.6e-49 166.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AJW71844.1 - 1.4e-28 98.6 0.2 4.6e-28 96.9 0.1 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AJW71844.1 - 6.1e-16 58.7 0.0 4e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AJW71844.1 - 2.9e-14 52.6 0.0 8.9e-09 34.7 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AJW71844.1 - 3e-14 53.4 0.1 3.6e-06 27.0 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 AJW71844.1 - 4.2e-13 49.5 0.1 4e-05 23.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AJW71844.1 - 1.9e-11 44.8 0.1 3.4e-05 24.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AJW71844.1 - 2.1e-10 40.6 0.0 0.00061 19.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 AJW71844.1 - 2.7e-10 39.5 1.2 0.00011 21.0 0.0 2.7 3 0 0 3 3 2 2 TIP49 C-terminus AAA_14 PF13173.1 AJW71844.1 - 5.8e-10 39.1 0.0 0.00017 21.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 AJW71844.1 - 8.1e-10 38.5 0.9 0.00088 19.0 0.1 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AJW71844.1 - 4e-09 35.8 0.3 6.6e-05 22.0 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.12 AJW71844.1 - 6.4e-09 35.4 0.3 0.0033 16.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 AJW71844.1 - 1e-07 31.9 0.0 0.0044 16.7 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 AJW71844.1 - 1.3e-07 31.2 4.1 0.0051 16.5 0.1 3.5 3 0 0 3 3 3 2 Part of AAA domain CDC48_2 PF02933.12 AJW71844.1 - 1.4e-07 31.0 0.1 3.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activat PF00158.21 AJW71844.1 - 1.8e-07 30.8 0.1 0.033 13.6 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 AJW71844.1 - 9.1e-07 28.9 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AJW71844.1 - 1.3e-06 28.5 0.0 0.037 14.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 AJW71844.1 - 1.4e-06 28.6 0.0 0.021 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 AJW71844.1 - 3.4e-06 26.3 2.1 0.098 11.7 0.0 3.9 3 1 1 4 4 4 2 KaiC PhoH PF02562.11 AJW71844.1 - 5.3e-06 25.8 0.2 0.068 12.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 AJW71844.1 - 5.7e-06 26.0 0.0 0.4 10.3 0.0 3.8 4 0 0 4 4 4 2 NACHT domain AAA_25 PF13481.1 AJW71844.1 - 5.9e-06 25.8 6.2 0.62 9.4 0.2 4.3 2 2 1 4 4 4 2 AAA domain Bac_DnaA PF00308.13 AJW71844.1 - 6e-06 26.0 0.0 0.0083 15.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein Mg_chelatase PF01078.16 AJW71844.1 - 6.8e-06 25.3 1.0 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 AJW71844.1 - 9.7e-06 25.6 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 AJW71844.1 - 4.5e-05 23.1 0.7 0.026 14.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 AJW71844.1 - 5.2e-05 22.2 0.0 0.095 11.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 AJW71844.1 - 7.3e-05 23.0 0.0 0.66 10.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.8 AJW71844.1 - 0.00012 21.0 0.0 0.085 11.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.6 AJW71844.1 - 0.00036 20.1 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 AJW71844.1 - 0.0004 20.1 0.4 3.5 7.3 0.0 3.9 2 1 1 3 3 3 0 NTPase DUF2075 PF09848.4 AJW71844.1 - 0.00063 18.8 0.0 0.32 9.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 AJW71844.1 - 0.0009 18.8 0.1 1.1 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 AJW71844.1 - 0.0012 18.4 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 AJW71844.1 - 0.0012 18.4 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 AJW71844.1 - 0.0012 17.7 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 SKI PF01202.17 AJW71844.1 - 0.0017 18.2 0.0 0.74 9.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase ResIII PF04851.10 AJW71844.1 - 0.0024 17.7 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AJW71844.1 - 0.0029 16.5 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein CPT PF07931.7 AJW71844.1 - 0.0081 15.8 0.0 0.86 9.2 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 AJW71844.1 - 0.0093 15.5 0.0 1.5 8.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Guanylate_kin PF00625.16 AJW71844.1 - 0.011 15.2 0.1 7.7 5.9 0.0 3.5 2 1 1 3 3 3 0 Guanylate kinase AAA_10 PF12846.2 AJW71844.1 - 0.013 14.9 0.5 1.8 7.9 0.0 3.2 2 2 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 AJW71844.1 - 0.017 14.6 0.2 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AFG1_ATPase PF03969.11 AJW71844.1 - 0.018 13.8 0.0 2.8 6.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Viral_helicase1 PF01443.13 AJW71844.1 - 0.042 13.3 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 AJW71844.1 - 0.052 13.0 0.0 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PIF1 PF05970.9 AJW71844.1 - 0.071 12.0 0.0 7.7 5.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase KAP_NTPase PF07693.9 AJW71844.1 - 0.079 11.9 0.0 6.6 5.6 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain IPT PF01745.11 AJW71844.1 - 0.14 11.2 0.2 10 5.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase DUF258 PF03193.11 AJW71844.1 - 0.15 11.2 0.0 8 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Torsin PF06309.6 AJW71844.1 - 0.18 11.6 0.1 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Torsin GatB_N PF02934.10 AJW71845.1 - 1e-74 251.0 0.1 1.8e-74 250.2 0.1 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AJW71845.1 - 8.5e-20 70.9 10.7 2.2e-19 69.6 7.4 1.8 1 0 0 1 1 1 1 GatB domain DUF2202 PF09968.4 AJW71845.1 - 1.2 8.7 8.0 0.34 10.5 1.8 2.6 2 1 1 3 3 3 0 Uncharacterized protein domain (DUF2202) Imm5 PF14423.1 AJW71846.1 - 0.033 13.8 0.3 0.033 13.8 0.2 1.0 1 0 0 1 1 1 0 Immunity protein Imm5 Yippee-Mis18 PF03226.9 AJW71846.1 - 0.084 12.9 0.5 0.12 12.4 0.3 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF844 PF05815.6 AJW71846.1 - 0.17 10.7 1.2 0.17 10.6 0.8 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) NT5C PF06941.7 AJW71847.1 - 2.4e-12 46.7 1.7 3.1e-12 46.3 1.2 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DnaJ PF00226.26 AJW71848.1 - 5.3e-27 93.3 2.2 8.4e-27 92.7 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AJW71848.1 - 1.4e-26 92.1 8.8 4.9e-21 74.4 1.0 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AJW71848.1 - 7.7e-15 54.7 21.4 1.7e-14 53.5 14.8 1.6 1 0 0 1 1 1 1 DnaJ central domain Cdc6_C PF09079.6 AJW71848.1 - 0.11 12.2 0.6 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 CDC6, C terminal HSP70 PF00012.15 AJW71849.1 - 3.1e-215 715.6 17.8 3.3e-212 705.6 12.3 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AJW71849.1 - 8.6e-18 64.0 5.3 8.6e-18 64.0 3.7 2.4 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AJW71849.1 - 0.00045 19.9 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GrpE PF01025.14 AJW71850.1 - 6.4e-40 136.4 2.3 7.6e-40 136.1 1.6 1.0 1 0 0 1 1 1 1 GrpE Exo70 PF03081.10 AJW71850.1 - 0.0095 14.7 0.3 0.012 14.4 0.2 1.1 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF4404 PF14357.1 AJW71850.1 - 0.015 15.7 2.0 0.03 14.7 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Retrotrans_gag PF03732.12 AJW71850.1 - 0.033 14.2 0.3 0.052 13.6 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Apolipoprotein PF01442.13 AJW71850.1 - 0.036 13.5 0.3 0.052 13.0 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TBPIP PF07106.8 AJW71850.1 - 0.038 13.5 4.4 0.075 12.5 3.1 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GP41 PF00517.12 AJW71850.1 - 0.079 12.5 1.1 0.13 11.7 0.6 1.4 1 1 0 1 1 1 0 Retroviral envelope protein Ribosomal_S6 PF01250.12 AJW71850.1 - 0.095 12.5 1.9 0.59 10.0 0.4 2.6 3 1 0 3 3 3 0 Ribosomal protein S6 Fib_alpha PF08702.5 AJW71850.1 - 0.26 11.3 2.9 0.37 10.8 1.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family 3HCDH_N PF02737.13 AJW71851.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF354 PF04007.7 AJW71852.1 - 2.1e-48 164.9 11.8 2.3e-48 164.7 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) LpxB PF02684.10 AJW71852.1 - 0.0018 16.9 0.4 0.0025 16.4 0.3 1.3 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.14 AJW71852.1 - 0.011 14.5 1.1 0.015 14.0 0.7 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF4174 PF13778.1 AJW71852.1 - 0.015 15.3 0.1 0.044 13.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) ABC2_membrane PF01061.19 AJW71853.1 - 6.7e-20 71.1 21.0 6.7e-20 71.1 14.6 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 AJW71853.1 - 8e-14 51.4 26.3 8e-14 51.4 18.2 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 AJW71853.1 - 1e-09 37.9 32.2 1.3e-09 37.5 22.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.1 AJW71853.1 - 0.27 10.4 32.2 2.4 7.3 22.3 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3493 PF11998.3 AJW71853.1 - 0.38 10.6 0.0 0.38 10.6 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3493) ABC_tran PF00005.22 AJW71854.1 - 2.2e-28 99.2 0.0 3.6e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AJW71854.1 - 7.7e-12 45.7 5.2 8.3e-10 39.0 0.5 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 AJW71854.1 - 1.3e-06 27.6 1.6 7.1e-06 25.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 AJW71854.1 - 0.0015 18.0 0.3 0.0027 17.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 AJW71854.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.16 AJW71854.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 AJW71854.1 - 0.079 11.7 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 AJW71854.1 - 0.12 11.5 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 AJW71854.1 - 0.14 12.4 7.9 0.92 9.7 5.5 2.2 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 AJW71854.1 - 0.18 11.0 1.4 12 5.0 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 AJW71854.1 - 0.33 10.7 5.2 4.4 7.0 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 tRNA_anti-codon PF01336.20 AJW71855.1 - 7e-15 54.6 0.1 0.00076 19.2 0.0 3.6 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain DUF3460 PF11943.3 AJW71855.1 - 0.18 11.9 0.4 0.96 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) DEAD PF00270.24 AJW71856.1 - 1e-38 132.5 0.2 4.6e-38 130.3 0.1 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase DEAD_assoc PF08494.6 AJW71856.1 - 5.7e-34 117.4 0.0 1.6e-33 116.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/H associated Helicase_C PF00271.26 AJW71856.1 - 6.2e-18 64.4 0.2 2e-15 56.4 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 AJW71856.1 - 1.5e-09 37.9 2.0 1.5e-09 37.9 0.4 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AJW71856.1 - 4.1e-07 29.1 0.0 8.3e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain MH1 PF03165.11 AJW71856.1 - 0.065 13.2 1.4 0.23 11.4 0.3 2.3 2 0 0 2 2 2 0 MH1 domain Ion_trans PF00520.26 AJW71857.1 - 0.045 13.0 0.0 0.047 12.9 0.0 1.0 1 0 0 1 1 1 0 Ion transport protein FixQ PF05545.6 AJW71857.1 - 0.049 13.2 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ VPEP PF07589.6 AJW71857.1 - 0.086 12.7 0.1 0.086 12.7 0.1 1.4 2 0 0 2 2 2 0 PEP-CTERM motif Rad51 PF08423.6 AJW71858.1 - 5.5e-30 104.1 0.0 6.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 AJW71858.1 - 1.4e-13 50.5 2.3 1.1e-12 47.5 1.6 2.0 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 AJW71858.1 - 7.6e-10 38.5 0.0 1.7e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 AJW71858.1 - 1.4e-08 34.2 0.0 1.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.24 AJW71858.1 - 0.00011 22.4 0.1 0.00017 21.7 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AJW71858.1 - 0.00019 21.1 0.8 0.00036 20.3 0.6 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 AJW71858.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AJW71858.1 - 0.00066 19.2 0.1 0.00081 18.9 0.1 1.1 1 0 0 1 1 1 1 AAA-like domain Zot PF05707.7 AJW71858.1 - 0.00071 19.1 0.1 0.00083 18.8 0.1 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) ABC_tran PF00005.22 AJW71858.1 - 0.0014 18.9 1.7 0.0017 18.6 1.0 1.5 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 AJW71858.1 - 0.0037 16.1 0.4 0.0074 15.1 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.12 AJW71858.1 - 0.0041 16.5 0.1 0.011 15.1 0.0 1.7 1 1 1 2 2 2 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 AJW71858.1 - 0.0043 15.7 0.1 0.0068 15.0 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 AJW71858.1 - 0.012 15.7 1.5 0.051 13.7 1.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AJW71858.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 AJW71858.1 - 0.05 14.0 3.8 5.6 7.4 0.0 3.4 2 2 2 4 4 4 0 Miro-like protein UvrD-helicase PF00580.16 AJW71858.1 - 0.064 12.5 2.0 0.39 9.9 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain ATP-synt_ab PF00006.20 AJW71858.1 - 0.076 12.4 0.1 0.091 12.2 0.1 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PAXNEB PF05625.6 AJW71858.1 - 0.11 11.2 5.1 0.16 10.7 0.6 2.1 2 0 0 2 2 2 0 PAXNEB protein Pox_polyA_pol_N PF12630.2 AJW71858.1 - 4.1 7.5 11.2 1.4 9.0 4.6 2.2 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain LSM PF01423.17 AJW71859.1 - 1.5e-18 66.1 1.5 1.7e-18 65.9 1.0 1.0 1 0 0 1 1 1 1 LSM domain Pox_A31 PF05771.6 AJW71859.1 - 0.042 13.6 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A31 protein S-AdoMet_synt_C PF02773.11 AJW71860.1 - 1.3e-71 238.7 0.0 2.3e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AJW71860.1 - 4.4e-50 168.6 0.4 3.3e-49 165.8 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AJW71860.1 - 3.5e-41 139.4 0.5 1.3e-40 137.6 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.14 AJW71860.1 - 0.00035 19.1 2.6 0.024 13.1 0.3 2.2 1 1 1 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) DUF3819 PF12842.2 AJW71860.1 - 0.019 14.6 0.0 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) NAD_binding_10 PF13460.1 AJW71861.1 - 1.2e-16 61.2 0.0 1.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AJW71861.1 - 5.2e-13 48.9 0.1 9.1e-12 44.9 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AJW71861.1 - 1.7e-09 37.3 4.1 2.6e-09 36.6 2.8 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 AJW71861.1 - 5.6e-09 35.1 1.1 5.5e-07 28.5 0.6 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AJW71861.1 - 8.6e-07 28.1 0.0 0.024 13.5 0.0 2.3 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 AJW71861.1 - 2.9e-06 26.3 0.3 0.0043 15.9 0.0 3.0 1 1 2 3 3 3 2 Male sterility protein PyocinActivator PF11112.3 AJW71861.1 - 0.033 14.0 1.7 44 4.0 0.0 4.0 4 1 0 4 4 4 0 Pyocin activator protein PrtN CbiD PF01888.12 AJW71862.1 - 2.2e-85 285.7 4.8 3.1e-85 285.2 3.3 1.2 1 0 0 1 1 1 1 CbiD DUF3042 PF11240.3 AJW71862.1 - 0.25 11.1 3.2 0.85 9.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) CbiG_N PF11760.3 AJW71863.1 - 2.6e-32 110.3 0.3 4.1e-32 109.7 0.2 1.3 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.11 AJW71863.1 - 1.6e-29 102.6 0.3 2.9e-29 101.7 0.0 1.6 2 0 0 2 2 2 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.3 AJW71863.1 - 7e-11 42.2 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis central region SpoU_sub_bind PF08032.7 AJW71863.1 - 0.00068 19.7 0.0 0.0028 17.7 0.0 2.1 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding CbiX PF01903.12 AJW71864.1 - 2.5e-33 114.3 0.0 2.6e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.6 AJW71864.1 - 1.1e-06 28.0 0.9 1.3e-06 27.6 0.6 1.3 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.14 AJW71864.1 - 3.3e-05 23.0 0.0 0.0025 16.8 0.0 2.0 1 1 0 1 1 1 1 Ferrochelatase CbiC PF02570.10 AJW71865.1 - 5e-72 241.5 0.8 5.6e-72 241.3 0.6 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase MCR_C PF04609.7 AJW71865.1 - 0.044 12.5 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C DUF3892 PF13031.1 AJW71865.1 - 0.13 12.7 0.4 1.7 9.1 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3892) GATase_3 PF07685.9 AJW71866.1 - 5.3e-33 113.8 0.2 8e-33 113.2 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.18 AJW71866.1 - 2.3e-23 82.6 0.0 5.6e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 AJW71866.1 - 7.1e-14 51.8 1.5 6.1e-09 35.7 0.0 2.7 2 1 1 3 3 3 2 AAA domain SNO PF01174.14 AJW71866.1 - 1.5e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase PF00117.23 AJW71866.1 - 0.0068 15.8 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.9 AJW71866.1 - 0.0086 15.1 1.3 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 CTP synthase N-terminus DUF2435 PF10363.4 AJW71866.1 - 0.095 12.6 0.1 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) CobA_CobO_BtuR PF02572.10 AJW71867.1 - 9.9e-63 210.8 0.2 1.1e-62 210.6 0.1 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_22 PF13401.1 AJW71867.1 - 0.0088 16.1 1.2 0.029 14.5 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AJW71867.1 - 0.011 15.6 1.0 0.022 14.6 0.7 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AJW71867.1 - 0.022 14.1 0.7 0.076 12.4 0.5 1.9 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 AJW71867.1 - 0.028 13.8 0.5 0.055 12.8 0.3 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.12 AJW71867.1 - 0.04 13.3 1.3 1.3 8.4 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 AJW71867.1 - 0.071 13.3 0.8 0.13 12.4 0.5 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AJW71867.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain ArsA_ATPase PF02374.10 AJW71867.1 - 0.14 11.1 0.7 2.1 7.2 0.2 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase EIF_2_alpha PF07541.7 AJW71868.1 - 5.5e-23 80.8 3.1 7.3e-23 80.4 0.4 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AJW71868.1 - 1.1e-10 41.4 0.6 3.3e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 S1 RNA binding domain MBT PF02820.13 AJW71868.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 mbt repeat NOP5NT PF08156.8 AJW71868.1 - 7.5 6.7 7.1 3.4 7.8 2.0 2.6 2 1 1 3 3 3 0 NOP5NT (NUC127) domain Nop10p PF04135.7 AJW71869.1 - 2.7e-25 87.8 3.2 2.8e-25 87.7 2.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Fer4_2 PF12797.2 AJW71869.1 - 0.06 13.2 1.8 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.22 AJW71869.1 - 0.11 12.0 1.8 6.8 6.4 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain PolC_DP2 PF03833.8 AJW71869.1 - 0.16 9.5 0.7 0.15 9.7 0.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.19 AJW71869.1 - 1.1 9.2 5.2 1.5 8.7 3.6 1.3 1 0 0 1 1 1 0 B-box zinc finger GCC2_GCC3 PF07699.8 AJW71869.1 - 1.5 8.4 7.3 38 3.9 5.0 2.1 1 1 0 1 1 1 0 GCC2 and GCC3 STT3 PF02516.9 AJW71870.1 - 3e-38 132.0 34.6 4.7e-38 131.3 24.0 1.3 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PBP PF01161.15 AJW71871.1 - 9e-37 126.1 0.1 1e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fcf1 PF04900.7 AJW71872.1 - 3.6e-08 33.4 0.0 4.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Fcf1 PIN_4 PF13638.1 AJW71872.1 - 0.00039 20.5 0.3 0.00048 20.2 0.2 1.2 1 0 0 1 1 1 1 PIN domain NEAT PF05031.7 AJW71872.1 - 0.087 12.8 0.8 0.16 11.9 0.3 1.6 1 1 0 1 1 1 0 Iron Transport-associated domain Recep_L_domain PF01030.19 AJW71872.1 - 0.1 12.5 1.3 0.17 11.8 0.8 1.6 1 1 0 1 1 1 0 Receptor L domain GTP_EFTU PF00009.22 AJW71873.1 - 9.4e-41 139.3 0.0 1.5e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AJW71873.1 - 9.5e-25 86.4 2.7 1.4e-24 85.9 0.1 2.5 3 0 0 3 3 3 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AJW71873.1 - 5.1e-05 23.3 0.3 0.00029 20.8 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AJW71873.1 - 0.00064 19.6 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOB1_Zn_bind PF08772.6 AJW71873.1 - 0.0084 15.9 0.2 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like FeoB_N PF02421.13 AJW71873.1 - 0.024 13.9 0.2 1.5 8.0 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Ribosomal_S6e PF01092.14 AJW71874.1 - 1.1e-20 73.5 0.3 1.3e-20 73.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e zinc_ribbon_4 PF13717.1 AJW71875.1 - 0.00034 20.2 3.2 0.0011 18.5 2.2 1.8 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AJW71875.1 - 0.00043 19.8 3.2 0.0012 18.3 2.2 1.7 1 1 0 1 1 1 1 zinc-ribbon domain IBR PF01485.16 AJW71875.1 - 0.0011 18.7 1.1 0.0017 18.1 0.8 1.3 1 0 0 1 1 1 1 IBR domain CpXC PF14353.1 AJW71875.1 - 0.0043 17.0 3.0 0.011 15.7 0.0 2.0 1 1 1 2 2 2 1 CpXC protein UPF0547 PF10571.4 AJW71875.1 - 0.0053 16.4 7.0 0.016 14.8 4.8 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 AJW71875.1 - 0.0054 16.3 0.8 0.0076 15.8 0.6 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 AJW71875.1 - 0.0057 15.8 4.2 0.11 11.7 3.6 2.0 1 1 1 2 2 2 2 zinc-ribbon domain zf-ISL3 PF14690.1 AJW71875.1 - 0.0081 16.1 0.8 0.91 9.6 0.1 2.1 1 1 1 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1 PF03811.8 AJW71875.1 - 0.011 15.1 2.1 0.81 9.2 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain Ribosomal_S27e PF01667.12 AJW71875.1 - 0.021 14.3 4.0 0.41 10.2 3.1 2.0 1 1 1 2 2 2 0 Ribosomal protein S27 DUF329 PF03884.9 AJW71875.1 - 0.026 14.0 3.3 2 8.0 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF329) Zn_Tnp_IS1595 PF12760.2 AJW71875.1 - 0.042 13.6 0.3 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Prok-RING_1 PF14446.1 AJW71875.1 - 0.051 13.3 3.1 0.067 12.9 2.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2387 PF09526.5 AJW71875.1 - 0.053 13.4 2.7 0.086 12.7 1.8 1.4 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 AJW71875.1 - 0.07 12.9 1.6 0.14 11.9 1.1 1.5 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 AJW71875.1 - 0.08 12.6 0.2 0.081 12.6 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS91 PF14319.1 AJW71875.1 - 0.083 12.4 0.1 0.083 12.4 0.1 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain PhnA_Zn_Ribbon PF08274.7 AJW71875.1 - 0.083 12.6 0.2 0.083 12.6 0.2 2.2 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf-C4_Topoisom PF01396.14 AJW71875.1 - 0.18 11.3 3.1 6 6.4 0.1 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Rota_NS26 PF01525.11 AJW71875.1 - 0.22 11.3 1.6 0.23 11.1 1.1 1.1 1 0 0 1 1 1 0 Rotavirus NS26 zf-H2C2_2 PF13465.1 AJW71875.1 - 0.28 11.5 4.6 3.8 7.9 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zinc-ribbons_6 PF07191.7 AJW71875.1 - 0.3 10.9 2.5 0.46 10.2 1.7 1.4 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_4 PF13894.1 AJW71875.1 - 0.31 11.4 1.9 3.9 8.0 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 AJW71875.1 - 0.33 11.2 0.4 0.33 11.2 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-RING_3 PF14369.1 AJW71875.1 - 0.34 10.9 6.7 0.49 10.4 0.4 2.2 1 1 1 2 2 2 0 zinc-finger Auto_anti-p27 PF06677.7 AJW71875.1 - 0.36 10.6 2.2 0.58 9.9 1.5 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.5 AJW71875.1 - 0.7 9.9 6.4 15 5.6 0.7 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 AJW71875.1 - 0.99 9.5 4.9 1.5 9.0 0.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.7 AJW71875.1 - 1.5 8.5 4.0 7.5 6.3 0.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-RING_4 PF14570.1 AJW71875.1 - 3.3 7.3 6.6 35 4.1 0.8 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.7 AJW71875.1 - 6.8 6.1 7.9 35 3.8 0.9 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding TPR_11 PF13414.1 AJW71876.1 - 2.6e-19 68.5 5.9 3.3e-13 49.0 2.9 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AJW71876.1 - 1.1e-17 62.7 14.9 1.8e-09 36.7 0.6 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 AJW71876.1 - 6.5e-16 56.9 7.3 8e-08 31.6 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 AJW71876.1 - 4.8e-13 48.1 6.0 0.00082 19.3 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AJW71876.1 - 1.9e-11 43.6 4.2 2.6e-06 27.2 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 AJW71876.1 - 1e-08 34.9 0.0 1e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AJW71876.1 - 3.7e-08 33.5 0.4 0.0036 17.5 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AJW71876.1 - 5.3e-08 32.8 0.0 0.0077 16.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AJW71876.1 - 8.6e-08 32.6 0.0 0.00019 22.0 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AJW71876.1 - 4.7e-07 29.1 0.5 0.00073 19.1 0.0 3.5 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AJW71876.1 - 2.5e-06 26.8 19.7 3.4e-05 23.3 0.6 5.0 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 AJW71876.1 - 4.4e-05 23.2 0.0 0.0016 18.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AJW71876.1 - 0.00021 21.5 2.4 0.44 11.1 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_C39_2 PF13529.1 AJW71876.1 - 0.00064 20.1 0.1 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase_C39 like family Fis1_TPR_C PF14853.1 AJW71876.1 - 0.21 11.5 2.2 6.6 6.6 0.1 2.9 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 AJW71876.1 - 0.34 11.0 6.4 2.1 8.5 4.4 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 GATase PF00117.23 AJW71877.1 - 5.4e-21 74.9 0.0 6.3e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AJW71877.1 - 8.4e-10 38.4 0.0 1.8e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 AJW71877.1 - 0.019 14.5 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 SNO glutamine amidotransferase family UPF0182 PF03699.8 AJW71878.1 - 1.3e-29 102.7 12.9 1.7e-28 99.0 9.0 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) DNA_primase_S PF01896.14 AJW71879.1 - 7e-16 58.3 0.7 6.7e-15 55.1 0.5 2.1 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit NRDD PF13597.1 AJW71879.1 - 0.0011 17.2 1.8 0.002 16.3 1.3 1.4 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase stn_TNFRSF12A PF12191.3 AJW71879.1 - 0.16 12.0 3.2 0.27 11.2 2.2 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PolC_DP2 PF03833.8 AJW71879.1 - 0.17 9.5 3.4 0.24 9.0 2.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DNA_primase_lrg PF04104.9 AJW71880.1 - 1.5e-25 89.9 0.0 3.4e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit AP_endonuc_2 PF01261.19 AJW71881.1 - 3.5e-31 108.1 0.0 6e-31 107.3 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel tRNA-synt_2b PF00587.20 AJW71882.1 - 8.7e-47 158.9 0.0 2.2e-46 157.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AJW71882.1 - 2e-17 62.8 0.4 7.7e-17 61.0 0.2 2.0 2 0 0 2 2 2 1 Anticodon binding domain Zn-ribbon_8 PF09723.5 AJW71882.1 - 0.021 14.7 0.3 7.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 AJW71882.1 - 0.042 13.4 3.6 1.9 8.1 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AJW71882.1 - 0.072 12.7 3.6 3.4 7.4 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain PA14 PF07691.7 AJW71883.1 - 4.1e-11 42.7 0.0 1.1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 PA14 domain HemolysinCabind PF00353.14 AJW71883.1 - 2.7e-08 33.4 100.6 0.0034 17.6 2.7 12.0 4 1 10 15 15 15 10 Hemolysin-type calcium-binding repeat (2 copies) DUF1250 PF06855.7 AJW71884.1 - 1e-10 40.9 0.1 22 4.6 0.0 7.0 7 0 0 7 7 7 6 Protein of unknown function (DUF1250) ESCRT-II PF05871.7 AJW71884.1 - 1.8e-08 34.3 8.6 2.3 8.1 0.1 6.3 1 1 6 7 7 7 6 ESCRT-II complex subunit Complex1_30kDa PF00329.14 AJW71884.1 - 0.00037 20.6 0.1 16 5.7 0.0 3.3 1 1 4 5 5 5 4 Respiratory-chain NADH dehydrogenase, 30 Kd subunit EF-hand_6 PF13405.1 AJW71884.1 - 0.39 10.7 21.5 1.5e+02 2.6 0.0 7.9 8 0 0 8 8 8 0 EF-hand domain Phage-tail_3 PF13550.1 AJW71884.1 - 0.41 10.4 16.9 10 5.8 0.8 3.9 1 1 4 5 5 5 0 Putative phage tail protein