# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Laminin_G_3 PF13385.6 AJW69701.1 - 1.8e-13 50.9 12.6 6.6e-13 49.1 2.2 4.4 3 1 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily SpaA PF17802.1 AJW69701.1 - 1.2e-05 25.5 6.8 6.6e-05 23.2 0.1 4.1 3 0 0 3 3 3 1 Prealbumin-like fold domain YtkA PF13115.6 AJW69701.1 - 0.00046 20.7 0.0 0.86 10.3 0.0 3.3 2 0 0 2 2 2 2 YtkA-like Filamin PF00630.19 AJW69701.1 - 0.01 16.6 1.1 0.12 13.3 0.0 3.2 3 0 0 3 3 3 0 Filamin/ABP280 repeat MG2 PF01835.19 AJW69701.1 - 0.047 14.1 0.9 5.4 7.5 0.0 4.4 5 0 0 5 5 5 0 MG2 domain DUF724 PF05266.14 AJW69701.1 - 5.9 6.7 12.3 14 5.4 12.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Asp_Glu_race PF01177.22 AJW69702.1 - 3.7e-11 43.3 0.0 4.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase HEPN_AbiV PF18728.1 AJW69702.1 - 0.0092 16.2 0.9 0.16 12.1 0.1 2.2 2 0 0 2 2 2 1 AbiV Snf7 PF03357.21 AJW69703.1 - 0.00049 19.7 8.3 0.0013 18.4 8.4 1.7 1 1 0 1 1 1 1 Snf7 KASH_CCD PF14662.6 AJW69703.1 - 0.0013 18.6 3.2 0.0013 18.6 3.2 1.6 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH BLOC1S3 PF15753.5 AJW69703.1 - 0.013 15.7 0.9 0.013 15.7 0.9 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Baculo_PEP_C PF04513.12 AJW69703.1 - 0.018 15.1 3.0 0.64 10.1 0.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 AJW69703.1 - 0.035 13.2 1.3 0.05 12.7 1.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2806 PF10987.8 AJW69703.1 - 0.035 14.0 0.2 0.048 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) Cas_Cas7 PF05107.12 AJW69703.1 - 0.042 13.4 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 Prominin PF05478.11 AJW69703.1 - 0.051 11.5 3.4 0.89 7.4 0.1 2.0 1 1 1 2 2 2 0 Prominin DASH_Duo1 PF08651.10 AJW69703.1 - 0.057 13.2 1.2 0.42 10.4 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Serine_rich PF08824.10 AJW69703.1 - 0.058 13.4 4.4 0.057 13.4 2.7 1.7 1 1 0 2 2 2 0 Serine rich protein interaction domain AAA_6 PF12774.7 AJW69703.1 - 0.071 12.1 1.0 0.11 11.5 1.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Flagellin_C PF00700.21 AJW69703.1 - 0.099 13.0 4.3 1.5 9.3 1.2 2.9 2 2 0 2 2 2 0 Bacterial flagellin C-terminal helical region FUSC PF04632.12 AJW69703.1 - 0.1 11.1 1.5 0.13 10.8 1.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rx_N PF18052.1 AJW69703.1 - 0.12 12.6 1.2 1 9.7 0.1 2.4 1 1 1 2 2 2 0 Rx N-terminal domain ATG16 PF08614.11 AJW69703.1 - 0.12 12.5 5.1 0.033 14.4 2.0 1.6 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 AJW69703.1 - 0.47 10.7 4.9 11 6.4 1.7 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 AJW69703.1 - 1.1 9.8 5.4 9.4 6.8 0.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.13 AJW69703.1 - 7 6.3 9.1 4.4 7.0 4.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Glycos_transf_2 PF00535.26 AJW69704.1 - 2.1e-31 109.1 0.0 3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 AJW69704.1 - 2.2e-20 73.0 8.5 4.7e-20 72.0 8.5 1.6 1 0 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.6 AJW69704.1 - 1.5e-09 38.1 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AJW69704.1 - 0.0046 16.5 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 NTP_transf_3 PF12804.7 AJW69704.1 - 0.0073 16.7 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF956 PF06115.11 AJW69705.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF956) TP_methylase PF00590.20 AJW69708.1 - 1.2e-47 162.6 0.1 1.4e-47 162.4 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PPR_1 PF12854.7 AJW69708.1 - 0.11 12.2 0.8 0.18 11.5 0.2 1.7 2 0 0 2 2 2 0 PPR repeat TP_methylase PF00590.20 AJW69709.1 - 6.5e-55 186.4 0.0 7.3e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PCMT PF01135.19 AJW69710.1 - 1.5e-15 57.5 0.5 2e-15 57.1 0.5 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AJW69710.1 - 2.7e-15 56.5 0.6 2e-14 53.7 0.2 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 AJW69710.1 - 7.3e-12 45.5 0.9 9.1e-12 45.1 0.9 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AJW69710.1 - 3.2e-11 43.2 1.5 4.3e-11 42.8 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AJW69710.1 - 5.2e-09 35.9 0.1 1.2e-08 34.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 AJW69710.1 - 8.7e-09 35.1 0.2 1.1e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AJW69710.1 - 1.1e-08 35.6 0.1 2.8e-08 34.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AJW69710.1 - 2.3e-06 27.2 0.1 9.1e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_3 PF01596.17 AJW69710.1 - 2.4e-06 26.9 0.1 3.1e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.20 AJW69710.1 - 2.6e-06 26.9 0.1 3.1e-06 26.7 0.1 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TrmK PF04816.12 AJW69710.1 - 9e-06 25.4 1.2 1.3e-05 24.9 1.2 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase UPF0020 PF01170.18 AJW69710.1 - 1.1e-05 25.2 0.2 6.3e-05 22.7 0.1 2.1 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 AJW69710.1 - 1.1e-05 25.1 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 AJW69710.1 - 1.9e-05 25.3 0.2 3.7e-05 24.4 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain GCD14 PF08704.10 AJW69710.1 - 3.7e-05 23.5 0.0 6.3e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.6 AJW69710.1 - 4.6e-05 24.4 0.0 6.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AJW69710.1 - 4.7e-05 23.2 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 AJW69710.1 - 5.2e-05 23.8 0.0 0.00013 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AJW69710.1 - 5.9e-05 22.8 0.0 0.00035 20.3 0.0 1.9 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F GidB PF02527.15 AJW69710.1 - 8e-05 22.0 0.1 0.00012 21.4 0.1 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G AviRa PF11599.8 AJW69710.1 - 0.00016 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_15 PF09445.10 AJW69710.1 - 0.0004 20.0 0.2 0.0006 19.4 0.2 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TehB PF03848.14 AJW69710.1 - 0.00062 19.2 0.2 0.002 17.6 0.0 1.7 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 AJW69710.1 - 0.0011 19.0 0.1 0.0022 18.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 AJW69710.1 - 0.0026 17.9 0.0 0.049 13.8 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase RrnaAD PF00398.20 AJW69710.1 - 0.0033 16.5 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 AJW69710.1 - 0.0092 15.6 0.5 0.015 14.9 0.5 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NAC PF01849.18 AJW69710.1 - 0.011 15.6 0.9 6.3 6.9 0.1 3.0 3 0 0 3 3 3 0 NAC domain Methyltransf_23 PF13489.6 AJW69710.1 - 0.018 14.9 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 AJW69710.1 - 0.025 14.1 0.2 0.045 13.3 0.2 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 SIS PF01380.22 AJW69710.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 1 1 1 2 2 2 0 SIS domain Spermine_synth PF01564.17 AJW69710.1 - 0.058 12.8 1.4 0.53 9.7 0.1 2.1 1 1 1 2 2 2 0 Spermine/spermidine synthase domain N6_Mtase PF02384.16 AJW69710.1 - 0.062 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_5 PF01795.19 AJW69710.1 - 0.064 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family CheR PF01739.18 AJW69710.1 - 0.11 12.0 0.0 0.62 9.5 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain PhoLip_ATPase_C PF16212.5 AJW69711.1 - 0.0035 17.1 0.1 0.0038 17.0 0.1 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal NMN_transporter PF04973.12 AJW69711.1 - 0.0054 16.7 0.3 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Nicotinamide mononucleotide transporter 7TM_GPCR_Srsx PF10320.9 AJW69711.1 - 0.0072 15.7 2.9 0.011 15.2 2.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4366 PF14283.6 AJW69711.1 - 0.019 15.0 0.1 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Keratin_assoc PF09775.9 AJW69711.1 - 0.048 13.3 1.0 0.076 12.7 1.0 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 DUF21 PF01595.20 AJW69711.1 - 0.052 13.3 0.1 0.078 12.7 0.1 1.3 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain NrsF PF06532.11 AJW69711.1 - 0.055 13.2 0.2 0.07 12.8 0.2 1.2 1 0 0 1 1 1 0 Negative regulator of sigma F DUF543 PF04418.12 AJW69711.1 - 0.056 13.4 0.0 0.091 12.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF543) Fig1 PF12351.8 AJW69711.1 - 0.14 12.0 4.5 0.063 13.2 1.7 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF202 PF02656.15 AJW69711.1 - 0.38 11.2 4.0 0.77 10.2 4.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF5379 PF17350.2 AJW69711.1 - 0.43 10.9 4.8 0.9 9.8 4.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5379) ATP_synt_H PF05493.13 AJW69711.1 - 0.85 10.1 5.8 0.26 11.8 2.5 1.8 1 1 1 2 2 2 0 ATP synthase subunit H FbpA PF05833.11 AJW69712.1 - 1.9e-41 142.3 10.2 2.4e-41 142.0 10.2 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 AJW69712.1 - 2.3e-21 76.5 0.0 7.2e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain PKcGMP_CC PF16808.5 AJW69712.1 - 0.049 13.5 2.8 0.22 11.4 2.8 2.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tweety PF04906.13 AJW69712.1 - 0.17 10.5 7.4 1.2 7.7 0.9 2.2 1 1 1 2 2 2 0 Tweety DUF126 PF01989.16 AJW69713.1 - 1.1e-30 105.3 0.1 1.7e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Aconitase X swivel domain DUF521 PF04412.13 AJW69714.1 - 5.6e-111 371.1 0.1 6.9e-111 370.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) HhH-GPD PF00730.25 AJW69715.1 - 1.7e-24 86.4 0.1 2.7e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AJW69715.1 - 2.8e-09 36.4 0.0 7.8e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif AGOG PF09171.10 AJW69715.1 - 0.0011 18.4 0.5 0.0046 16.3 0.0 1.9 2 0 0 2 2 2 1 N-glycosylase/DNA lyase DUF2400 PF09674.10 AJW69715.1 - 0.0039 17.2 0.1 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_5 PF14520.6 AJW69715.1 - 0.0041 17.7 0.8 0.17 12.6 0.1 2.4 1 1 1 2 2 2 1 Helix-hairpin-helix domain ATP-sulfurylase PF01747.17 AJW69717.1 - 8.4e-84 280.3 0.0 1.2e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 AJW69717.1 - 2.6e-46 157.2 0.0 5.2e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.19 AJW69718.1 - 6.6e-45 153.3 0.0 7.9e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Peptidase_S8_N PF16361.5 AJW69718.1 - 0.098 13.1 0.0 0.18 12.3 0.0 1.5 1 1 0 1 1 1 0 N-terminal of Subtilase family Peroxin-22 PF12827.7 AJW69719.1 - 0.14 12.1 2.1 0.16 11.9 0.4 2.1 2 1 0 2 2 2 0 Peroxisomal biogenesis protein family Glyco_trans_1_3 PF13528.6 AJW69720.1 - 2.7e-05 23.6 0.0 0.072 12.3 0.0 2.4 2 1 0 2 2 2 2 Glycosyl transferase family 1 Ribosomal_L32p PF01783.23 AJW69721.1 - 0.011 16.0 0.1 0.011 16.0 0.1 2.4 3 0 0 3 3 3 0 Ribosomal L32p protein family TF_Zn_Ribbon PF08271.12 AJW69721.1 - 0.021 14.3 0.6 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 AJW69721.1 - 0.028 14.3 0.9 0.86 9.6 0.1 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.12 AJW69721.1 - 0.19 11.7 1.8 2.2 8.3 1.0 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 AJW69721.1 - 0.98 9.5 5.2 9.5 6.3 5.2 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain G10 PF01125.17 AJW69722.1 - 0.0017 18.1 1.5 0.87 9.3 0.1 2.1 1 1 1 2 2 2 2 G10 protein adh_short PF00106.25 AJW69723.1 - 1.4e-57 194.3 0.1 1.8e-57 194.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJW69723.1 - 5.2e-38 130.9 0.0 6.4e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJW69723.1 - 1.6e-14 54.2 0.2 2.5e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AJW69723.1 - 0.0085 15.3 0.1 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 AJW69723.1 - 0.052 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 AJW69723.1 - 0.057 12.8 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AJW69723.1 - 0.072 12.5 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LPG_synthase_TM PF03706.13 AJW69724.1 - 6.2e-22 78.5 15.2 8.3e-22 78.1 15.2 1.2 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region CPP1-like PF11833.8 AJW69724.1 - 0.19 11.4 5.5 1.5 8.4 5.3 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SWIRM-assoc_1 PF16495.5 AJW69725.1 - 0.047 13.6 2.4 0.057 13.4 2.4 1.3 1 1 0 1 1 1 0 SWIRM-associated region 1 ATP_bind_1 PF03029.17 AJW69726.1 - 1.7e-56 191.7 0.0 2e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 AJW69726.1 - 0.00017 22.0 0.0 0.00059 20.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 AJW69726.1 - 0.0019 17.3 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 AJW69726.1 - 0.003 17.4 0.1 0.24 11.2 0.1 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF2075 PF09848.9 AJW69726.1 - 0.0062 15.8 0.1 0.012 14.9 0.1 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) GTP_EFTU PF00009.27 AJW69726.1 - 0.0064 16.1 0.1 0.75 9.3 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ParA PF10609.9 AJW69726.1 - 0.011 15.2 0.4 0.098 12.1 0.4 2.1 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RsgA_GTPase PF03193.16 AJW69726.1 - 0.013 15.4 0.5 1.9 8.4 0.1 3.0 3 0 0 3 3 3 0 RsgA GTPase Imm61 PF15598.6 AJW69726.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.7 1 1 1 2 2 2 0 Immunity protein 61 CbiA PF01656.23 AJW69726.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 AJW69726.1 - 0.039 14.3 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 AJW69726.1 - 0.043 13.0 0.0 0.062 12.5 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 AJW69726.1 - 0.064 13.2 0.1 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 AJW69726.1 - 0.071 12.7 0.2 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AJW69726.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 AJW69726.1 - 0.088 12.4 2.9 1.4 8.5 0.1 2.2 1 1 0 2 2 2 0 AAA domain ATPase PF06745.13 AJW69726.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 KaiC T2SSE PF00437.20 AJW69726.1 - 0.1 11.6 0.1 0.23 10.5 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 AJW69726.1 - 0.12 12.0 1.0 4.3 6.9 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AJW69726.1 - 0.17 12.4 0.1 0.31 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain GHMP_kinases_N PF00288.26 AJW69727.1 - 1.9e-13 50.4 2.2 4e-13 49.4 2.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJW69727.1 - 1e-07 32.2 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal QueC PF06508.13 AJW69728.1 - 1e-47 162.4 0.0 1.2e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 AJW69728.1 - 6.2e-05 22.5 0.0 7.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 AJW69728.1 - 7.4e-05 22.6 0.1 0.0001 22.1 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 AJW69728.1 - 0.013 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD synthase GTP_cyclohydroI PF01227.22 AJW69730.1 - 1.2e-63 213.8 0.0 1.3e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 AJW69730.1 - 0.0086 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein OST-HTH PF12872.7 AJW69730.1 - 0.053 13.3 0.1 1.4 8.8 0.0 2.4 3 0 0 3 3 3 0 OST-HTH/LOTUS domain Fer4_12 PF13353.6 AJW69731.1 - 1.6e-13 51.1 0.9 7.5e-13 48.9 0.1 2.0 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AJW69731.1 - 7.4e-13 48.7 0.9 2.6e-12 46.9 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AJW69731.1 - 1.9e-09 38.2 0.1 2.3e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily SKG6 PF08693.10 AJW69732.1 - 0.0085 15.5 4.4 0.033 13.6 1.6 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 AJW69732.1 - 0.87 9.4 6.8 2.2 8.1 2.0 2.0 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Saf_2TM PF18303.1 AJW69732.1 - 3.6 7.2 7.8 2.5 7.7 1.5 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain SMBP PF16785.5 AJW69733.1 - 0.00065 19.9 5.4 0.066 13.4 0.1 3.1 3 0 0 3 3 3 2 Small metal-binding protein FliS PF02561.14 AJW69733.1 - 0.024 14.9 0.2 0.024 14.9 0.2 3.8 3 1 1 4 4 4 0 Flagellar protein FliS FCD PF07729.12 AJW69733.1 - 0.074 13.5 2.5 12 6.3 0.0 3.1 2 1 1 3 3 3 0 FCD domain CPSase_L_D3 PF02787.19 AJW69733.1 - 0.33 11.3 9.7 1.1 9.7 4.6 3.0 2 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Ubiquitin_3 PF14836.6 AJW69733.1 - 1.1 9.2 5.3 0.39 10.7 0.3 2.6 2 1 1 3 3 3 0 Ubiquitin-like domain Alkyl_sulf_dimr PF14863.6 AJW69733.1 - 1.2 9.5 5.0 0.77 10.2 0.5 2.7 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation MAS20 PF02064.15 AJW69733.1 - 1.7 8.7 7.5 0.52 10.4 0.2 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor TPR_6 PF13174.6 AJW69733.1 - 4.8 8.0 7.4 24 5.8 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Lipoprotein_10 PF03202.13 AJW69733.1 - 4.9 7.6 12.8 5.9 7.4 2.8 2.5 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region ERp29 PF07749.12 AJW69733.1 - 5.5 8.0 16.3 32 5.5 8.1 3.8 1 1 2 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain HTH_24 PF13412.6 AJW69734.1 - 0.00019 20.9 0.1 0.0012 18.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_micro PF17007.5 AJW69734.1 - 0.0047 15.8 0.6 0.0066 15.3 0.6 1.3 1 0 0 1 1 1 1 HTH-like MarR_2 PF12802.7 AJW69734.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_45 PF14947.6 AJW69735.1 - 3.5e-10 39.7 0.0 4.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 AJW69735.1 - 1.4e-05 24.9 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AJW69735.1 - 0.00036 21.0 0.0 0.00052 20.5 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.6 AJW69735.1 - 0.0026 17.5 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) RNA_pol_Rpc34 PF05158.12 AJW69735.1 - 0.0039 16.6 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Mrr_N PF14338.6 AJW69735.1 - 0.0059 16.7 0.0 0.036 14.2 0.0 1.9 1 1 1 2 2 2 1 Mrr N-terminal domain DUF1495 PF07381.11 AJW69735.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.6 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) HTH_20 PF12840.7 AJW69735.1 - 0.041 14.0 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AJW69735.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 AJW69735.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) MarR PF01047.22 AJW69735.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family DDRGK PF09756.9 AJW69735.1 - 0.12 11.9 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 DDRGK domain AAA_5 PF07728.14 AJW69737.1 - 0.0083 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HMMR_N PF15905.5 AJW69738.1 - 2.3e-05 24.1 11.7 2.3e-05 24.1 11.7 1.3 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 AJW69738.1 - 0.0004 20.4 6.8 0.00052 20.0 5.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 AJW69738.1 - 0.0013 17.7 11.3 0.0016 17.4 11.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 AJW69738.1 - 0.0015 18.7 12.3 0.0015 18.7 12.3 2.1 1 1 1 2 2 2 2 Tropomyosin like CREPT PF16566.5 AJW69738.1 - 0.0018 18.5 3.7 0.0022 18.2 3.7 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour TMF_DNA_bd PF12329.8 AJW69738.1 - 0.0051 16.8 10.0 0.0051 16.8 10.0 2.7 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 AJW69738.1 - 0.0061 16.6 6.6 0.0094 16.0 6.6 1.4 1 0 0 1 1 1 1 Laminin Domain II Prefoldin PF02996.17 AJW69738.1 - 0.0068 16.3 7.8 0.046 13.6 2.1 2.6 1 1 1 2 2 2 1 Prefoldin subunit DUF812 PF05667.11 AJW69738.1 - 0.011 14.7 8.8 0.013 14.4 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) OmpH PF03938.14 AJW69738.1 - 0.013 15.8 3.2 0.02 15.3 3.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 AJW69738.1 - 0.014 14.1 7.1 0.016 13.9 7.1 1.1 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 AJW69738.1 - 0.015 15.1 7.7 0.015 15.1 7.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prominin PF05478.11 AJW69738.1 - 0.021 12.8 4.8 0.024 12.6 4.8 1.0 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 AJW69738.1 - 0.027 14.5 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Taxilin PF09728.9 AJW69738.1 - 0.029 13.6 9.5 0.034 13.3 9.2 1.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein MitMem_reg PF13012.6 AJW69738.1 - 0.031 14.7 0.4 0.043 14.2 0.4 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Rx_N PF18052.1 AJW69738.1 - 0.034 14.4 3.9 0.056 13.7 3.9 1.4 1 0 0 1 1 1 0 Rx N-terminal domain Flagellin_C PF00700.21 AJW69738.1 - 0.035 14.5 1.7 0.37 11.2 0.2 2.2 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Baculo_F PF12259.8 AJW69738.1 - 0.035 12.6 5.1 0.05 12.1 5.1 1.2 1 0 0 1 1 1 0 Baculovirus F protein FemAB PF02388.16 AJW69738.1 - 0.038 12.9 1.6 0.05 12.5 1.6 1.2 1 0 0 1 1 1 0 FemAB family DUF16 PF01519.16 AJW69738.1 - 0.045 14.2 12.4 0.2 12.2 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 AJW69738.1 - 0.047 12.9 2.4 0.059 12.6 2.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein IFT57 PF10498.9 AJW69738.1 - 0.048 12.6 7.6 0.059 12.3 7.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mei5 PF10376.9 AJW69738.1 - 0.066 13.1 10.0 0.087 12.7 9.2 1.6 1 1 0 1 1 1 0 Double-strand recombination repair protein DUF3450 PF11932.8 AJW69738.1 - 0.078 12.3 7.3 0.11 11.7 5.5 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ADIP PF11559.8 AJW69738.1 - 0.082 13.0 7.4 2.5 8.2 7.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2009 PF09418.10 AJW69738.1 - 0.085 11.9 2.5 0.099 11.7 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF4763 PF15960.5 AJW69738.1 - 0.1 11.9 4.7 0.13 11.5 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) THOC7 PF05615.13 AJW69738.1 - 0.12 12.6 7.2 2 8.7 7.0 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 DHR10 PF18595.1 AJW69738.1 - 0.13 12.3 8.7 0.11 12.6 7.4 1.6 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Spectrin PF00435.21 AJW69738.1 - 0.13 12.7 5.9 0.68 10.4 4.5 2.4 1 1 1 2 2 2 0 Spectrin repeat Nas2_N PF18265.1 AJW69738.1 - 0.14 12.1 7.0 3 7.8 0.1 3.3 3 1 0 3 3 3 0 Nas2 N_terminal domain DUF948 PF06103.11 AJW69738.1 - 0.16 12.2 3.7 3.1 8.1 0.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 AJW69738.1 - 0.25 11.8 5.3 2.5 8.6 2.1 2.3 1 1 1 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.12 AJW69738.1 - 0.32 11.5 5.5 9.7 6.7 5.5 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SPAM PF02090.15 AJW69738.1 - 0.34 10.7 7.8 5.3 6.8 7.7 2.0 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein SOAR PF16533.5 AJW69738.1 - 0.36 10.8 4.8 3.9 7.5 1.2 2.6 1 1 1 2 2 2 0 STIM1 Orai1-activating region SlyX PF04102.12 AJW69738.1 - 0.39 11.4 2.9 2.8 8.6 2.9 2.3 1 1 0 1 1 1 0 SlyX Fmp27_WPPW PF10359.9 AJW69738.1 - 0.4 9.5 8.6 0.19 10.6 4.5 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Prefoldin_2 PF01920.20 AJW69738.1 - 0.45 10.5 10.6 3.6 7.6 5.4 2.7 1 1 1 2 2 2 0 Prefoldin subunit GldM_N PF12081.8 AJW69738.1 - 0.46 10.5 7.9 0.18 11.8 2.7 2.1 1 1 1 2 2 2 0 GldM N-terminal domain CortBP2 PF09727.9 AJW69738.1 - 0.5 10.2 11.5 0.13 12.2 4.8 2.0 1 1 1 2 2 2 0 Cortactin-binding protein-2 PLA2G12 PF06951.11 AJW69738.1 - 0.52 10.2 2.3 12 5.7 0.3 2.2 1 1 1 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Syntaxin_2 PF14523.6 AJW69738.1 - 0.63 10.4 7.6 16 5.9 7.3 2.6 1 1 0 1 1 1 0 Syntaxin-like protein UPF0242 PF06785.11 AJW69738.1 - 0.64 10.1 9.0 0.91 9.6 9.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 AJW69738.1 - 0.76 9.9 6.3 0.73 9.9 4.6 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FAM76 PF16046.5 AJW69738.1 - 0.8 9.0 8.7 0.94 8.8 8.7 1.1 1 0 0 1 1 1 0 FAM76 protein CC2-LZ PF16516.5 AJW69738.1 - 0.89 10.0 9.3 2.6 8.5 2.8 2.9 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Atg14 PF10186.9 AJW69738.1 - 0.98 8.4 9.7 1.4 8.0 9.7 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 AJW69738.1 - 0.99 10.1 7.1 0.52 11.0 1.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF4250 PF14056.6 AJW69738.1 - 1.2 9.2 3.4 12 5.9 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Fib_alpha PF08702.10 AJW69738.1 - 1.2 9.3 8.0 1.8 8.7 6.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 AJW69738.1 - 1.4 9.2 7.1 2 8.8 3.0 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) KH_5 PF13184.6 AJW69738.1 - 1.6 8.9 5.8 9.9 6.3 0.3 3.0 3 1 0 3 3 2 0 NusA-like KH domain DUF4200 PF13863.6 AJW69738.1 - 2.1 8.8 11.9 18 5.7 10.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) XhlA PF10779.9 AJW69738.1 - 7.1 6.9 14.2 5.3 7.3 5.0 2.8 1 1 2 3 3 3 0 Haemolysin XhlA YtxH PF12732.7 AJW69738.1 - 7.9 7.1 7.4 94 3.6 7.4 2.7 1 1 0 1 1 1 0 YtxH-like protein Snf7 PF03357.21 AJW69739.1 - 0.00032 20.3 1.6 0.00049 19.8 1.6 1.3 1 1 0 1 1 1 1 Snf7 Flagellin_N PF00669.20 AJW69739.1 - 0.018 15.2 0.4 0.043 13.9 0.4 1.7 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF2806 PF10987.8 AJW69739.1 - 0.04 13.8 0.2 0.063 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) ATG16 PF08614.11 AJW69739.1 - 1.8 8.7 5.6 0.14 12.4 0.8 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) adh_short_C2 PF13561.6 AJW69741.1 - 2.3e-72 243.3 0.0 2.8e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AJW69741.1 - 1.1e-60 204.5 0.1 1.3e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AJW69741.1 - 2.2e-08 34.2 0.0 3.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AJW69741.1 - 0.0022 17.5 0.4 0.0053 16.3 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AJW69741.1 - 0.016 14.5 0.1 0.034 13.5 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HRG PF16954.5 AJW69742.1 - 0.11 12.9 3.4 0.2 12.1 0.2 2.2 1 1 1 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF2953 PF11167.8 AJW69742.1 - 0.35 11.0 2.8 15 5.8 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2953) DUF4064 PF13273.6 AJW69742.1 - 1 9.7 7.2 13 6.1 6.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Inositol_P PF00459.25 AJW69743.1 - 1.8e-51 175.3 0.1 2e-51 175.1 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AJW69743.1 - 0.011 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain APS_kinase PF01583.20 AJW69744.1 - 7.3e-51 172.2 0.0 8.6e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AJW69744.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AJW69744.1 - 0.00022 20.6 0.0 0.00037 19.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 AJW69744.1 - 0.00045 20.8 0.0 0.00085 19.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 AJW69744.1 - 0.0039 16.7 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 AJW69744.1 - 0.0047 17.4 0.0 0.0086 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain Ferrochelatase PF00762.19 AJW69744.1 - 0.013 14.6 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 Ferrochelatase AAA_28 PF13521.6 AJW69744.1 - 0.027 14.7 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 AJW69744.1 - 0.064 13.1 0.0 2.6 7.9 0.0 2.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arf PF00025.21 AJW69744.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Hemerythrin PF01814.23 AJW69745.1 - 7.5e-11 42.8 0.4 1.2e-10 42.1 0.1 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain HSBP1 PF06825.12 AJW69745.1 - 0.11 12.4 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Na_H_Exchanger PF00999.21 AJW69746.1 - 2.5e-36 125.3 48.1 3.2e-36 124.9 48.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TFIIB PF00382.19 AJW69747.1 - 1.4e-32 111.5 6.7 9.6e-16 57.6 0.5 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW69747.1 - 2.7e-09 36.4 0.4 4.5e-09 35.7 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_11 PF08279.12 AJW69747.1 - 0.0052 16.7 0.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 HTH domain RPA_interact_C PF14768.6 AJW69747.1 - 0.011 16.3 0.0 0.038 14.6 0.0 2.0 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Sigma70_r4 PF04545.16 AJW69747.1 - 0.011 15.2 0.0 0.031 13.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 zinc_ribbon_2 PF13240.6 AJW69747.1 - 0.014 15.1 1.4 0.062 13.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Sigma70_r4_2 PF08281.12 AJW69747.1 - 0.022 14.4 0.3 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 AJW69747.1 - 0.023 14.5 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cyclin_C PF02984.19 AJW69747.1 - 0.025 14.6 0.1 3.4 7.8 0.0 2.3 1 1 1 2 2 2 0 Cyclin, C-terminal domain Cyclin_N PF00134.23 AJW69747.1 - 0.027 14.2 0.4 0.066 13.0 0.1 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain Phage_terminase PF10668.9 AJW69747.1 - 0.048 13.7 0.3 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Phage terminase small subunit RB_B PF01857.20 AJW69747.1 - 0.057 13.5 0.2 0.1 12.6 0.2 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-FPG_IleRS PF06827.14 AJW69747.1 - 0.11 12.4 0.2 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HTH_23 PF13384.6 AJW69747.1 - 0.12 12.2 1.4 0.47 10.3 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain zf-ribbon_3 PF13248.6 AJW69747.1 - 0.17 11.3 1.3 0.87 9.1 1.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 AJW69747.1 - 0.26 11.1 1.0 0.5 10.2 1.0 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain Auto_anti-p27 PF06677.12 AJW69747.1 - 0.3 11.3 1.5 0.56 10.4 1.5 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CARDB PF07705.11 AJW69748.1 - 0.00027 21.2 0.0 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.9 AJW69748.1 - 0.088 13.1 0.0 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4508 PF14969.6 AJW69749.1 - 0.023 14.9 0.1 0.039 14.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) CRCB PF02537.15 AJW69752.1 - 1.5e-19 70.1 5.1 1.8e-19 69.8 5.1 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF2104 PF09877.9 AJW69752.1 - 0.0051 17.0 1.0 0.0085 16.3 0.4 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2104) DUF1059 PF06348.11 AJW69753.1 - 9.8e-07 28.9 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) AAA_lid_9 PF17871.1 AJW69753.1 - 0.0025 17.7 0.0 0.0031 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA lid domain TFIIB PF00382.19 AJW69754.1 - 4.8e-32 109.8 1.3 1.1e-15 57.5 0.3 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW69754.1 - 5.9e-05 22.5 0.2 0.00015 21.2 0.2 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 AJW69754.1 - 0.0045 16.7 0.1 2.4 7.9 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain HTH_11 PF08279.12 AJW69754.1 - 0.059 13.3 0.5 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 HTH domain UPF0242 PF06785.11 AJW69755.1 - 7.7e-06 26.1 0.2 9.6e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 AJW69755.1 - 1.8e-05 24.4 3.1 2.3e-05 24.0 3.1 1.1 1 0 0 1 1 1 1 Leucine zipper ATG16 PF08614.11 AJW69755.1 - 4.5e-05 23.8 0.2 5.5e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 AJW69755.1 - 6.2e-05 22.0 5.3 8.1e-05 21.6 5.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6_N PF17675.1 AJW69755.1 - 0.0002 21.9 1.6 0.00021 21.8 1.6 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Phage_GP20 PF06810.11 AJW69755.1 - 0.00034 20.5 5.8 0.00049 19.9 5.8 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF5082 PF16888.5 AJW69755.1 - 0.00034 20.9 6.6 0.00049 20.4 6.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) TonB_N PF16031.5 AJW69755.1 - 0.00044 20.8 9.0 0.00051 20.6 9.0 1.1 1 0 0 1 1 1 1 TonB polyproline region TSC22 PF01166.18 AJW69755.1 - 0.00044 20.5 4.4 0.0053 17.0 1.2 2.6 1 1 1 2 2 2 1 TSC-22/dip/bun family DUF4763 PF15960.5 AJW69755.1 - 0.00047 19.6 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) bZIP_1 PF00170.21 AJW69755.1 - 0.00068 19.7 11.0 0.0068 16.5 1.7 2.2 1 1 1 2 2 2 2 bZIP transcription factor CENP-F_leu_zip PF10473.9 AJW69755.1 - 0.00077 19.5 6.3 0.0012 18.9 6.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 AJW69755.1 - 0.00081 18.8 4.5 0.0011 18.4 4.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ZapB PF06005.12 AJW69755.1 - 0.0014 19.1 8.5 0.004 17.6 6.1 2.1 1 1 0 1 1 1 1 Cell division protein ZapB LRRFIP PF09738.9 AJW69755.1 - 0.0014 18.2 0.2 0.0017 17.9 0.2 1.3 1 0 0 1 1 1 1 LRRFIP family HALZ PF02183.18 AJW69755.1 - 0.0014 18.8 5.6 0.032 14.4 5.6 2.2 1 1 0 1 1 1 1 Homeobox associated leucine zipper ADIP PF11559.8 AJW69755.1 - 0.0018 18.4 5.6 0.0022 18.1 5.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 AJW69755.1 - 0.0019 18.1 7.8 0.0025 17.7 7.8 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4988 PF16378.5 AJW69755.1 - 0.002 17.8 1.8 0.002 17.8 1.8 1.6 1 1 1 2 2 2 1 Domain of unknown function RNA_pol_Rpb1_1 PF04997.12 AJW69755.1 - 0.002 17.5 3.5 0.0026 17.1 3.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DivIC PF04977.15 AJW69755.1 - 0.0022 17.7 7.7 0.02 14.7 6.6 2.2 1 1 1 2 2 2 2 Septum formation initiator BRE1 PF08647.11 AJW69755.1 - 0.0023 18.0 7.7 0.0032 17.5 7.7 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 AJW69755.1 - 0.0026 17.1 5.0 0.0034 16.7 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DivIVA PF05103.13 AJW69755.1 - 0.0036 17.4 5.0 0.0052 16.9 5.0 1.1 1 0 0 1 1 1 1 DivIVA protein DUF812 PF05667.11 AJW69755.1 - 0.0037 16.2 0.6 0.0038 16.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4795 PF16043.5 AJW69755.1 - 0.0039 16.8 0.2 0.0043 16.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) HMMR_C PF15908.5 AJW69755.1 - 0.0045 17.3 2.0 0.0063 16.8 2.0 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal Baculo_PEP_C PF04513.12 AJW69755.1 - 0.0058 16.7 4.8 0.0078 16.3 4.8 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Sipho_Gp157 PF05565.11 AJW69755.1 - 0.0067 16.5 2.4 0.01 15.9 2.4 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 CENP-Q PF13094.6 AJW69755.1 - 0.0087 16.3 1.1 0.01 16.0 1.1 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit GIT_CC PF16559.5 AJW69755.1 - 0.0093 15.8 3.1 0.017 14.9 2.5 1.7 1 1 1 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor Spc29 PF17082.5 AJW69755.1 - 0.011 15.6 0.5 0.015 15.2 0.5 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 EMP24_GP25L PF01105.24 AJW69755.1 - 0.013 15.4 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Mei5 PF10376.9 AJW69755.1 - 0.015 15.2 6.1 0.024 14.5 6.1 1.5 1 1 0 1 1 1 0 Double-strand recombination repair protein DUF1465 PF07323.12 AJW69755.1 - 0.016 15.0 1.6 0.022 14.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) FapA PF03961.13 AJW69755.1 - 0.017 13.7 1.5 0.022 13.4 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAP1_N PF04849.13 AJW69755.1 - 0.018 14.3 6.2 0.025 13.8 6.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region LPP PF04728.13 AJW69755.1 - 0.018 15.4 1.8 0.54 10.7 1.8 2.1 1 1 0 1 1 1 0 Lipoprotein leucine-zipper XhlA PF10779.9 AJW69755.1 - 0.021 15.0 7.9 0.091 13.0 7.9 2.0 1 1 0 1 1 1 0 Haemolysin XhlA DUF4164 PF13747.6 AJW69755.1 - 0.022 15.0 5.2 0.036 14.3 5.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Csm1_N PF18504.1 AJW69755.1 - 0.024 15.0 5.0 0.039 14.3 5.0 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF4407 PF14362.6 AJW69755.1 - 0.025 14.0 1.1 0.035 13.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2353 PF09789.9 AJW69755.1 - 0.027 13.9 4.1 0.033 13.6 4.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GOLGA2L5 PF15070.6 AJW69755.1 - 0.027 13.1 3.4 0.036 12.7 3.4 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 SKA2 PF16740.5 AJW69755.1 - 0.029 14.2 1.4 0.054 13.3 1.4 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Atg14 PF10186.9 AJW69755.1 - 0.029 13.5 3.3 0.036 13.2 3.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 AJW69755.1 - 0.029 14.4 4.0 0.04 13.9 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Wtap PF17098.5 AJW69755.1 - 0.029 14.3 3.0 0.041 13.8 3.0 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family Cep57_MT_bd PF06657.13 AJW69755.1 - 0.029 14.8 2.5 0.062 13.8 2.5 1.6 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Filament PF00038.21 AJW69755.1 - 0.029 13.9 4.5 0.038 13.6 4.5 1.1 1 0 0 1 1 1 0 Intermediate filament protein Tho2 PF11262.8 AJW69755.1 - 0.032 13.5 2.7 0.041 13.1 2.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Jnk-SapK_ap_N PF09744.9 AJW69755.1 - 0.033 14.4 4.1 0.045 14.0 4.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 AJW69755.1 - 0.034 14.6 5.2 0.046 14.1 3.8 1.8 1 1 1 2 2 2 0 Snapin/Pallidin HemX PF04375.14 AJW69755.1 - 0.039 13.2 2.7 0.049 12.9 2.7 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4686 PF15742.5 AJW69755.1 - 0.04 13.0 7.2 0.049 12.8 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF2968 PF11180.8 AJW69755.1 - 0.041 13.5 1.4 0.062 12.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4515 PF14988.6 AJW69755.1 - 0.042 13.7 5.4 0.046 13.6 4.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) bZIP_2 PF07716.15 AJW69755.1 - 0.047 13.8 7.9 0.11 12.7 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TLE_N PF03920.15 AJW69755.1 - 0.055 13.6 1.6 0.094 12.8 1.6 1.4 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain AAA_13 PF13166.6 AJW69755.1 - 0.058 12.0 4.3 0.07 11.8 4.3 1.0 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 AJW69755.1 - 0.061 10.8 3.7 0.073 10.6 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cep57_CLD_2 PF14197.6 AJW69755.1 - 0.061 13.4 3.2 0.11 12.6 3.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Taxilin PF09728.9 AJW69755.1 - 0.064 12.4 8.3 0.085 12.0 8.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CENP-H PF05837.12 AJW69755.1 - 0.066 13.6 4.6 0.094 13.1 4.6 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 AJW69755.1 - 0.069 13.5 3.9 0.08 13.4 2.5 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Sec34 PF04136.15 AJW69755.1 - 0.07 13.0 3.4 0.091 12.6 3.4 1.1 1 0 0 1 1 1 0 Sec34-like family DUF2205 PF10224.9 AJW69755.1 - 0.071 13.1 5.3 1 9.4 0.3 2.3 1 1 1 2 2 2 0 Short coiled-coil protein Lge1 PF11488.8 AJW69755.1 - 0.08 13.1 6.1 0.13 12.4 5.6 1.6 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 FlxA PF14282.6 AJW69755.1 - 0.083 12.9 8.5 0.18 11.8 8.5 1.5 1 1 0 1 1 1 0 FlxA-like protein Prominin PF05478.11 AJW69755.1 - 0.086 10.8 2.6 0.11 10.4 2.6 1.1 1 0 0 1 1 1 0 Prominin DHR10 PF18595.1 AJW69755.1 - 0.1 12.6 6.0 0.15 12.1 6.0 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF4200 PF13863.6 AJW69755.1 - 0.11 12.9 5.6 0.17 12.3 5.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) GrpE PF01025.19 AJW69755.1 - 0.11 12.2 4.6 0.15 11.7 4.6 1.2 1 0 0 1 1 1 0 GrpE Prefoldin_2 PF01920.20 AJW69755.1 - 0.11 12.5 8.2 0.041 13.8 4.1 1.9 1 1 1 2 2 2 0 Prefoldin subunit Fungal_TACC PF12709.7 AJW69755.1 - 0.12 12.9 6.3 0.089 13.3 3.7 1.9 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Ax_dynein_light PF10211.9 AJW69755.1 - 0.13 12.2 6.6 0.22 11.5 6.6 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain Cortex-I_coil PF09304.10 AJW69755.1 - 0.15 12.3 5.2 0.21 11.8 5.2 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil TMF_TATA_bd PF12325.8 AJW69755.1 - 0.15 12.3 6.5 0.32 11.2 6.2 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Trypan_PARP PF05887.11 AJW69755.1 - 0.16 12.0 14.8 0.24 11.4 14.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMPIT PF07851.13 AJW69755.1 - 0.16 11.2 3.2 0.23 10.7 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 AJW69755.1 - 0.16 12.4 3.7 0.37 11.3 3.7 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.17 AJW69755.1 - 0.18 11.7 8.2 1 9.3 1.7 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF16 PF01519.16 AJW69755.1 - 0.2 12.2 5.5 0.34 11.4 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 USP8_interact PF08941.10 AJW69755.1 - 0.2 11.5 1.5 0.26 11.1 1.5 1.1 1 0 0 1 1 1 0 USP8 interacting Paralemmin PF03285.15 AJW69755.1 - 0.2 11.2 4.1 0.3 10.6 4.1 1.3 1 0 0 1 1 1 0 Paralemmin Spc24 PF08286.11 AJW69755.1 - 0.2 11.9 5.7 0.33 11.2 5.7 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 GLE1 PF07817.13 AJW69755.1 - 0.22 10.7 1.4 0.32 10.2 1.4 1.2 1 0 0 1 1 1 0 GLE1-like protein DUF724 PF05266.14 AJW69755.1 - 0.23 11.3 3.9 0.31 10.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LURAP PF14854.6 AJW69755.1 - 0.25 11.3 1.8 0.32 10.9 1.8 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein Flagellin_C PF00700.21 AJW69755.1 - 0.27 11.6 3.8 1.9 8.9 0.2 2.1 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region SlyX PF04102.12 AJW69755.1 - 0.29 11.8 13.1 0.32 11.6 3.1 2.6 2 1 1 3 3 2 0 SlyX YabA PF06156.13 AJW69755.1 - 0.3 11.7 3.8 0.52 11.0 3.8 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TolA_bind_tri PF16331.5 AJW69755.1 - 0.38 10.9 6.0 1.2 9.2 5.9 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation NPV_P10 PF05531.12 AJW69755.1 - 0.38 11.2 4.8 0.83 10.2 4.8 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Rho_Binding PF08912.11 AJW69755.1 - 0.45 11.4 6.6 7 7.6 6.6 2.2 1 1 0 1 1 1 0 Rho Binding CtIP_N PF10482.9 AJW69755.1 - 0.48 10.5 6.3 5.9 7.0 5.6 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF2312 PF10073.9 AJW69755.1 - 0.6 9.8 4.7 2.3 7.9 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TMF_DNA_bd PF12329.8 AJW69755.1 - 0.66 10.0 13.0 1.9 8.6 2.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FemAB PF02388.16 AJW69755.1 - 0.78 8.5 2.9 0.96 8.2 2.9 1.1 1 0 0 1 1 1 0 FemAB family DUF3972 PF13118.6 AJW69755.1 - 0.92 10.0 8.8 2.1 8.8 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) Swi5 PF07061.11 AJW69755.1 - 1.2 9.3 6.0 4.2 7.5 5.9 1.9 1 1 0 1 1 1 0 Swi5 Terminase_3 PF04466.13 AJW69756.1 - 0.0026 17.3 0.2 0.0027 17.3 0.2 1.0 1 0 0 1 1 1 1 Phage terminase large subunit Evr1_Alr PF04777.13 AJW69756.1 - 0.0056 17.1 0.1 0.0061 17.0 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Pox_vIL-18BP PF05566.12 AJW69756.1 - 0.044 14.0 0.0 0.049 13.9 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein AAA PF00004.29 AJW69757.1 - 1.1e-99 330.0 0.0 8.2e-50 168.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AJW69757.1 - 3.3e-24 84.4 5.0 7.3e-13 48.1 0.2 3.0 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 AJW69757.1 - 5.1e-22 77.8 0.1 1.4e-21 76.4 0.1 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 AJW69757.1 - 2.9e-17 63.3 0.4 6.2e-08 32.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AJW69757.1 - 1.7e-15 57.8 0.0 5.8e-07 30.0 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 AJW69757.1 - 1.5e-14 54.1 0.0 6.5e-08 32.5 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AJW69757.1 - 1.1e-13 51.4 1.0 9.1e-06 25.7 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 AJW69757.1 - 1.5e-11 43.9 0.5 4.1e-11 42.5 0.5 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 AJW69757.1 - 1.2e-10 41.7 0.0 0.00012 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 AJW69757.1 - 3e-10 39.8 0.7 0.00042 19.6 0.0 2.9 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_22 PF13401.6 AJW69757.1 - 4e-10 40.1 2.5 0.0083 16.4 0.0 4.2 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.6 AJW69757.1 - 1.6e-09 37.8 0.0 0.00058 19.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 AJW69757.1 - 2.6e-08 34.5 0.0 0.0015 19.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 AJW69757.1 - 7.6e-08 32.3 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 AJW69757.1 - 9.6e-08 31.6 0.3 0.013 14.9 0.0 2.8 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AJW69757.1 - 4.6e-07 29.7 0.4 0.14 11.9 0.0 4.1 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 AJW69757.1 - 6.7e-07 29.2 0.0 0.0063 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 AJW69757.1 - 1.2e-06 28.9 0.0 0.066 13.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 AJW69757.1 - 2.4e-06 27.0 0.1 0.017 14.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 AJW69757.1 - 2.5e-06 27.1 0.0 0.071 12.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 AJW69757.1 - 3.8e-06 26.8 0.0 0.036 13.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AJW69757.1 - 6.4e-06 26.7 0.4 0.2 12.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_28 PF13521.6 AJW69757.1 - 9.1e-06 26.0 0.1 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 AJW69757.1 - 2.9e-05 24.1 1.1 0.69 9.9 0.1 3.2 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 AJW69757.1 - 5.1e-05 23.2 0.4 0.09 12.5 0.1 2.5 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 AJW69757.1 - 6.4e-05 22.2 0.0 0.28 10.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.6 AJW69757.1 - 7e-05 22.6 0.2 0.13 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 AJW69757.1 - 9e-05 21.7 0.3 0.2 10.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 AJW69757.1 - 0.00012 21.8 3.7 1.2 8.7 0.2 3.5 2 2 1 3 3 3 2 AAA domain PhoH PF02562.16 AJW69757.1 - 0.00015 21.3 0.3 0.53 9.7 0.1 2.7 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 AJW69757.1 - 0.00018 21.4 1.2 2.6 7.9 0.1 3.9 3 1 1 4 4 3 1 NACHT domain Vps4_C PF09336.10 AJW69757.1 - 0.00031 20.7 0.9 0.051 13.6 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain UFD1 PF03152.14 AJW69757.1 - 0.00087 18.8 0.2 0.0019 17.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Sigma54_activ_2 PF14532.6 AJW69757.1 - 0.00088 19.4 0.0 0.81 9.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 AJW69757.1 - 0.00091 18.6 0.0 0.96 8.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 AJW69757.1 - 0.0021 17.4 5.1 0.65 9.3 0.1 3.9 3 1 0 4 4 4 1 KaiC AAA_17 PF13207.6 AJW69757.1 - 0.0022 18.4 0.0 2.2 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AJW69757.1 - 0.0039 16.6 0.0 1.5 8.2 0.0 3.1 3 0 0 3 3 2 1 Bacterial TniB protein AAA_19 PF13245.6 AJW69757.1 - 0.004 17.5 3.5 1.4 9.3 0.0 3.4 4 0 0 4 4 2 1 AAA domain NB-ARC PF00931.22 AJW69757.1 - 0.0048 16.1 0.1 3.9 6.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 AJW69757.1 - 0.0055 16.6 1.8 3.1 7.7 0.0 3.8 2 1 1 3 3 3 0 NTPase ResIII PF04851.15 AJW69757.1 - 0.0057 16.7 0.1 0.77 9.7 0.0 3.0 2 1 0 3 3 2 1 Type III restriction enzyme, res subunit CPT PF07931.12 AJW69757.1 - 0.0063 16.4 0.1 0.29 11.0 0.0 2.7 2 1 0 3 3 2 1 Chloramphenicol phosphotransferase-like protein Bac_DnaA PF00308.18 AJW69757.1 - 0.0073 16.2 0.0 2.1 8.1 0.0 3.2 2 1 1 3 3 3 1 Bacterial dnaA protein T2SSE PF00437.20 AJW69757.1 - 0.0082 15.2 0.0 2.4 7.1 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Hydin_ADK PF17213.3 AJW69757.1 - 0.013 15.7 1.0 0.16 12.2 0.0 2.6 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 AJW69757.1 - 0.014 15.1 1.0 5 6.8 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase Viral_helicase1 PF01443.18 AJW69757.1 - 0.017 14.8 0.0 0.19 11.4 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase LID PF17916.1 AJW69757.1 - 0.018 14.6 0.2 0.041 13.5 0.2 1.5 1 0 0 1 1 1 0 LIM interaction domain (LID) Guanylate_kin PF00625.21 AJW69757.1 - 0.024 14.3 0.6 21 4.7 0.0 4.0 3 1 1 4 4 4 0 Guanylate kinase SKI PF01202.22 AJW69757.1 - 0.029 14.5 0.1 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.15 AJW69757.1 - 0.03 14.2 1.8 1.2 9.0 0.0 3.1 3 2 0 3 3 2 0 Rad17 P-loop domain PIF1 PF05970.14 AJW69757.1 - 0.03 13.5 0.0 2.1 7.4 0.0 2.6 2 0 0 2 2 2 0 PIF1-like helicase DUF4894 PF16235.5 AJW69757.1 - 0.037 14.4 0.4 0.093 13.1 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4894) AFG1_ATPase PF03969.16 AJW69757.1 - 0.039 12.8 0.0 7.8 5.3 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase ATPase_2 PF01637.18 AJW69757.1 - 0.042 13.8 0.4 2 8.3 0.1 3.3 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea IPT PF01745.16 AJW69757.1 - 0.042 13.2 0.4 6.4 6.1 0.1 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.11 AJW69757.1 - 0.05 13.7 0.1 2 8.5 0.0 2.7 2 0 0 2 2 2 0 Torsin KTI12 PF08433.10 AJW69757.1 - 0.86 9.0 3.5 9.2 5.6 0.0 3.4 5 0 0 5 5 2 0 Chromatin associated protein KTI12 HSP20 PF00011.21 AJW69758.1 - 7.2e-07 29.3 6.2 1.4e-05 25.2 6.2 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AJW69758.1 - 1.2e-05 24.8 0.1 1.9e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 AJW69758.1 - 0.00057 20.3 0.2 0.00085 19.7 0.2 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain DUF1207 PF06727.11 AJW69758.1 - 0.12 11.3 0.4 0.17 10.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) HMA PF00403.26 AJW69758.1 - 0.16 12.5 3.0 0.3 11.6 3.0 1.5 1 0 0 1 1 1 0 Heavy-metal-associated domain ACT_7 PF13840.6 AJW69759.1 - 5.8e-08 32.4 0.2 1.1e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 ACT domain SecD-TM1 PF13721.6 AJW69759.1 - 0.0077 16.7 0.2 0.024 15.1 0.0 1.8 2 0 0 2 2 2 1 SecD export protein N-terminal TM region Pyr_redox_2 PF07992.14 AJW69760.1 - 2.6e-49 168.0 0.0 3.3e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJW69760.1 - 4.4e-15 56.0 0.4 9.1e-10 39.0 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJW69760.1 - 3.4e-06 26.9 0.0 5.2 6.5 0.0 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AJW69760.1 - 0.0013 18.1 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AJW69760.1 - 0.015 15.3 0.0 9.3 6.2 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 AJW69760.1 - 0.056 12.5 0.3 6.8 5.7 0.5 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AJW69760.1 - 0.07 13.4 0.0 12 6.2 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AJW69760.1 - 0.13 11.1 0.0 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 AJW69760.1 - 0.14 11.4 0.0 8.4 5.6 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 AJW69760.1 - 0.15 11.1 0.0 13 4.7 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 AJW69760.1 - 0.28 10.2 0.4 27 3.7 0.0 3.0 3 0 0 3 3 3 0 FAD binding domain Pro_isomerase PF00160.21 AJW69761.1 - 1.2e-46 158.9 0.1 2e-46 158.1 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbP PF01789.16 AJW69761.1 - 0.00014 22.0 0.2 0.00029 21.0 0.2 1.6 1 1 0 1 1 1 1 PsbP bPH_3 PF14470.6 AJW69762.1 - 0.023 15.0 0.1 1.5 9.3 0.0 2.4 2 1 0 2 2 2 0 Bacterial PH domain Hint PF01079.20 AJW69762.1 - 0.13 11.8 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Hint module HEPN_RES_NTD1 PF18870.1 AJW69762.1 - 0.41 10.8 6.0 31 4.8 5.9 2.2 1 1 0 1 1 1 0 HEPN/RES N-terminal domain 1 TP_methylase PF00590.20 AJW69763.1 - 6.9e-33 114.4 0.0 7.9e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MMR_HSR1_Xtn PF16897.5 AJW69763.1 - 0.047 13.7 0.9 0.13 12.3 0.9 1.8 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GcpE PF04551.14 AJW69763.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 GcpE protein Copper-bind PF00127.20 AJW69764.1 - 1.8e-05 25.1 0.0 3.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family tRNA_anti-codon PF01336.25 AJW69764.1 - 0.12 12.4 0.2 11 6.1 0.1 2.9 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain SpoIIM PF01944.17 AJW69765.1 - 7.1e-06 26.1 16.6 1e-05 25.6 16.6 1.2 1 0 0 1 1 1 1 Stage II sporulation protein M DNA_pol_E_B PF04042.16 AJW69766.1 - 5e-22 78.3 0.0 9.3e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 AJW69766.1 - 2.3e-13 51.1 0.0 4.1e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJW69766.1 - 1.9e-08 34.6 0.0 9.1e-08 32.5 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DNA_pol_D_N PF18018.1 AJW69766.1 - 0.17 12.0 0.4 0.63 10.1 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase delta subunit OB-fold domain Cdc6_C PF09079.11 AJW69767.1 - 5.7e-15 55.1 0.3 1.5e-14 53.8 0.3 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 AJW69767.1 - 7e-13 49.0 0.3 2e-12 47.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AJW69767.1 - 2.3e-10 41.1 0.5 1.8e-09 38.2 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AJW69767.1 - 4.6e-10 40.0 0.1 1.7e-09 38.2 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AJW69767.1 - 2.3e-07 30.9 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 AJW69767.1 - 3.5e-07 29.8 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein ATPase_2 PF01637.18 AJW69767.1 - 2.1e-06 27.8 1.4 2.1e-06 27.8 1.4 2.4 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 AJW69767.1 - 0.00034 19.9 0.0 0.00099 18.4 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 AJW69767.1 - 0.00073 19.6 0.2 0.0031 17.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 AJW69767.1 - 0.00081 18.7 0.1 0.0011 18.3 0.0 1.4 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 AJW69767.1 - 0.001 19.4 0.0 0.0029 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 AJW69767.1 - 0.0015 18.8 0.3 0.0046 17.3 0.3 1.8 1 0 0 1 1 1 1 AAA C-terminal domain TIP49_C PF17856.1 AJW69767.1 - 0.0021 18.1 0.1 0.0064 16.6 0.1 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain DUF512 PF04459.12 AJW69767.1 - 0.0054 16.0 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF512) KAP_NTPase PF07693.14 AJW69767.1 - 0.0055 16.0 0.0 1.2 8.4 0.0 2.5 1 1 0 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.22 AJW69767.1 - 0.0055 17.1 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 AJW69767.1 - 0.0065 16.3 0.4 0.046 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_32 PF13654.6 AJW69767.1 - 0.0074 15.1 0.4 0.45 9.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 AJW69767.1 - 0.0081 15.4 0.0 0.037 13.2 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase HTH_36 PF13730.6 AJW69767.1 - 0.015 15.2 0.0 0.061 13.3 0.0 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain DUF815 PF05673.13 AJW69767.1 - 0.017 14.3 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 AJW69767.1 - 0.018 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 AJW69767.1 - 0.02 14.8 0.3 0.2 11.6 0.3 2.4 1 1 0 1 1 1 0 NTPase UvrD-helicase PF00580.21 AJW69767.1 - 0.023 14.2 0.1 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.9 AJW69767.1 - 0.028 13.3 0.0 0.075 11.9 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 AJW69767.1 - 0.038 14.0 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 AJW69767.1 - 0.039 13.7 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 AJW69767.1 - 0.042 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 AJW69767.1 - 0.043 13.8 0.0 2.1 8.3 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 AJW69767.1 - 0.05 13.8 0.0 0.19 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AJW69767.1 - 0.063 12.6 0.1 0.24 10.6 0.0 1.9 3 0 0 3 3 3 0 Zeta toxin Herpes_U26 PF07402.11 AJW69767.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Human herpesvirus U26 protein Torsin PF06309.11 AJW69767.1 - 0.098 12.8 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.6 AJW69767.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Penicillinase_R PF03965.16 AJW69768.1 - 0.004 17.5 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 Penicillinase repressor HTH_ABP1_N PF18107.1 AJW69768.1 - 0.027 14.2 0.6 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain MazE_antitoxin PF04014.18 AJW69769.1 - 9.4e-07 28.6 0.1 1.1e-06 28.4 0.1 1.1 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin Rubredoxin_C PF18267.1 AJW69769.1 - 0.0062 16.4 0.1 0.0081 16.1 0.1 1.1 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain eIF-1a PF01176.19 AJW69769.1 - 0.014 15.2 0.1 0.024 14.5 0.1 1.5 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 AbrB-like PF14250.6 AJW69769.1 - 0.09 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 AbrB-like transcriptional regulator MraZ PF02381.18 AJW69769.1 - 0.17 11.9 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like TrmB PF01978.19 AJW69770.1 - 1.6e-05 24.7 0.1 3.4e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AJW69770.1 - 3.5e-05 24.2 0.1 5.8e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AJW69770.1 - 0.0023 17.8 0.1 0.0071 16.2 0.1 1.9 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 AJW69770.1 - 0.0034 17.5 0.2 0.0066 16.6 0.2 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Replic_Relax PF13814.6 AJW69770.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation HTH_45 PF14947.6 AJW69770.1 - 0.013 15.5 0.5 0.036 14.1 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DUF4364 PF14277.6 AJW69770.1 - 0.044 13.5 2.1 0.064 13.0 0.0 2.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4364) PspB PF06667.12 AJW69770.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B HTH_Crp_2 PF13545.6 AJW69770.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AJW69770.1 - 0.18 12.2 0.4 2.2 8.7 0.0 2.5 2 1 1 3 3 3 0 Transcriptional regulator FliH PF02108.16 AJW69771.1 - 0.073 13.1 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Flagellar assembly protein FliH PcrB PF01884.17 AJW69772.1 - 1.1e-51 175.5 0.1 1.4e-51 175.1 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 AJW69772.1 - 3.6e-08 33.2 0.3 4.1e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.25 AJW69772.1 - 1.2e-07 31.1 0.1 1.5e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain B12-binding PF02310.19 AJW69772.1 - 0.00035 20.6 0.5 1.2 9.2 0.0 3.7 3 1 0 3 3 3 1 B12 binding domain ThiG PF05690.14 AJW69772.1 - 0.0083 15.5 0.5 1.1 8.5 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 AJW69772.1 - 0.0097 15.0 0.1 0.33 10.0 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NanE PF04131.14 AJW69772.1 - 0.014 14.6 1.9 0.52 9.5 0.1 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Ribul_P_3_epim PF00834.19 AJW69772.1 - 0.019 14.4 0.3 0.082 12.3 0.1 1.9 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Trp_syntA PF00290.20 AJW69772.1 - 0.049 12.5 1.2 0.25 10.2 0.2 2.2 2 1 1 3 3 3 0 Tryptophan synthase alpha chain IGPS PF00218.21 AJW69772.1 - 0.052 12.7 0.2 0.77 8.9 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 AJW69772.1 - 0.066 12.5 0.1 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase DpaA_N PF16924.5 AJW69772.1 - 0.079 13.0 0.4 0.57 10.3 0.1 2.1 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Peripla_BP_1 PF00532.21 AJW69772.1 - 0.12 11.8 0.2 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family G3P_antiterm PF04309.12 AJW69772.1 - 0.16 11.3 1.3 0.48 9.8 0.1 2.3 2 1 1 3 3 3 0 Glycerol-3-phosphate responsive antiterminator PolC_DP2 PF03833.13 AJW69773.1 - 0 1038.0 0.0 0 1037.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 AJW69773.1 - 3.8 7.6 15.0 14 5.7 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_10 PF10058.9 AJW69773.1 - 3.9 7.3 8.3 4.2 7.2 4.3 2.6 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein SHMT PF00464.19 AJW69774.1 - 7.7e-76 255.2 0.0 1e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AJW69774.1 - 6.4e-07 28.9 0.1 3.4e-06 26.5 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AJW69774.1 - 8e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 AJW69774.1 - 0.00033 19.8 0.0 0.00052 19.1 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_5 PF00266.19 AJW69774.1 - 0.00043 19.4 0.2 0.0012 17.9 0.2 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cpn60_TCP1 PF00118.24 AJW69775.1 - 1.6e-182 607.5 20.4 1.9e-182 607.3 20.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.17 AJW69775.1 - 0.003 17.5 4.7 0.2 11.6 1.8 2.5 2 0 0 2 2 2 2 DAK2 domain Ustilago_mating PF05722.12 AJW69775.1 - 0.1 12.1 0.2 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Ustilago B locus mating-type protein ADK PF00406.22 AJW69775.1 - 0.11 12.5 0.7 2.4 8.3 0.7 2.6 1 1 0 1 1 1 0 Adenylate kinase DUF240 PF03086.14 AJW69775.1 - 0.13 12.2 1.1 3.1 7.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF240) Cytadhesin_P30 PF07271.11 AJW69775.1 - 0.95 9.0 9.6 1.6 8.2 9.6 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 RseC_MucC PF04246.12 AJW69776.1 - 2.6 8.0 5.1 1.3 9.0 3.1 1.5 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Gln-synt_C PF00120.24 AJW69777.1 - 8.2e-115 383.5 0.0 9.7e-115 383.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AJW69777.1 - 2.6e-27 94.4 0.0 5.5e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Npun_R1517 PF18068.1 AJW69778.1 - 0.001 19.3 2.4 0.0017 18.7 0.3 2.1 2 1 0 2 2 2 1 Npun R1517 Ca_bind_SSO6904 PF18249.1 AJW69778.1 - 0.16 12.3 4.2 0.19 12.1 0.7 2.6 1 1 1 3 3 3 0 Calcium binding protein SSO6904 CLN6 PF15156.6 AJW69779.1 - 0.0045 16.3 0.3 0.0051 16.1 0.3 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 B12D PF06522.11 AJW69779.1 - 0.039 13.8 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-AN1 PF01428.16 AJW69780.1 - 6.2e-12 45.5 8.1 8.2e-12 45.1 8.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger RecR PF02132.15 AJW69780.1 - 0.048 13.2 1.5 0.086 12.4 1.5 1.4 1 0 0 1 1 1 0 RecR protein PSI_integrin PF17205.3 AJW69780.1 - 0.052 13.3 6.0 3.7 7.4 6.0 2.2 1 1 0 1 1 1 0 Integrin plexin domain Transp_Tc5_C PF04236.15 AJW69780.1 - 0.089 13.2 3.8 0.16 12.4 3.8 1.4 1 1 0 1 1 1 0 Tc5 transposase C-terminal domain zf-C2H2_4 PF13894.6 AJW69780.1 - 2.5 9.2 6.9 0.68 10.9 2.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.25 AJW69781.1 - 2.1e-62 210.0 0.7 2.6e-62 209.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJW69781.1 - 1.8e-46 158.6 0.8 2.2e-46 158.3 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJW69781.1 - 2.8e-13 50.2 0.3 3.7e-13 49.8 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AJW69781.1 - 0.0019 17.7 0.2 0.22 11.0 0.2 2.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 AJW69781.1 - 0.15 11.8 1.0 0.36 10.6 1.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_2 PF07992.14 AJW69782.1 - 2.4e-25 89.4 0.0 3.5e-24 85.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJW69782.1 - 1.9e-07 31.5 1.1 0.0013 19.3 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AJW69782.1 - 0.00042 20.0 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AJW69782.1 - 0.00074 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AJW69782.1 - 0.003 17.6 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 AJW69782.1 - 0.005 15.7 0.0 0.0073 15.2 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 AJW69782.1 - 0.075 12.1 0.0 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 AJW69782.1 - 0.23 10.7 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain His_Me_b4a2 PF18275.1 AJW69783.1 - 0.0068 16.5 3.1 0.0068 16.5 3.1 1.8 1 1 0 1 1 1 1 His-Me finger endonuclease beta4-alpha2 domain RIO1 PF01163.22 AJW69784.1 - 3.4e-05 23.5 1.4 3.9e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 AJW69784.1 - 4.8e-05 22.8 1.6 4.8e-05 22.8 1.6 2.0 1 1 1 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 AJW69784.1 - 0.005 16.5 1.2 0.036 13.7 1.2 2.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase SAM_Exu PF18609.1 AJW69784.1 - 0.058 13.5 1.4 0.16 12.1 1.4 1.8 1 0 0 1 1 1 0 Exuperantia SAM-like domain tRNA_NucTransf2 PF09249.11 AJW69785.1 - 6.1e-36 123.1 0.1 1.3e-35 122.1 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.23 AJW69785.1 - 6.5e-11 42.4 0.5 2.2e-10 40.7 0.5 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AJW69785.1 - 8e-05 22.7 0.2 0.00026 21.0 0.2 1.9 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase SMODS PF18144.1 AJW69785.1 - 0.00015 22.0 1.1 0.00035 20.8 1.1 1.6 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DZF PF07528.14 AJW69785.1 - 0.022 14.4 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 DZF domain AMP-binding_C PF13193.6 AJW69785.1 - 0.041 14.9 0.0 0.087 13.8 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain LigT_PEase PF02834.16 AJW69786.1 - 3.5e-27 94.4 0.0 3.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 AJW69786.1 - 7.2e-14 52.2 0.1 2.7e-13 50.3 0.1 1.8 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 AJW69786.1 - 8.2e-09 35.5 0.0 9.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AAA_17 PF13207.6 AJW69787.1 - 3.7e-14 53.3 0.2 4.9e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJW69787.1 - 6.4e-13 49.4 0.1 9.4e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AJW69787.1 - 2.2e-05 24.7 0.1 4.5e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AJW69787.1 - 0.00042 20.6 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AJW69787.1 - 0.0007 19.5 0.1 0.0069 16.3 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase CoaE PF01121.20 AJW69787.1 - 0.0015 18.3 0.1 0.0049 16.6 0.0 1.8 1 1 1 2 2 2 1 Dephospho-CoA kinase MeaB PF03308.16 AJW69787.1 - 0.013 14.5 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytidylate_kin2 PF13189.6 AJW69787.1 - 0.015 15.5 0.3 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family ADK PF00406.22 AJW69787.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase AAA PF00004.29 AJW69787.1 - 0.019 15.4 0.2 0.039 14.4 0.2 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AJW69787.1 - 0.02 14.2 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 AJW69787.1 - 0.027 13.7 0.2 0.042 13.0 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 AJW69787.1 - 0.043 13.3 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 AJW69787.1 - 0.044 14.1 0.1 0.072 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AJW69787.1 - 0.048 13.6 0.2 0.16 11.8 0.2 1.9 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 AJW69787.1 - 0.069 13.7 0.4 0.08 13.5 0.4 1.3 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 AJW69787.1 - 0.082 12.6 0.2 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain ATP_bind_2 PF03668.15 AJW69787.1 - 0.088 12.1 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_5 PF07728.14 AJW69787.1 - 0.097 12.7 0.2 0.19 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UPF0180 PF03698.13 AJW69787.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) RNA_binding PF01877.17 AJW69788.1 - 3.2e-13 50.0 0.1 6.5e-13 49.0 0.1 1.4 1 1 0 1 1 1 1 RNA binding EspB PF05802.11 AJW69789.1 - 0.024 14.6 0.7 0.031 14.3 0.7 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF5065 PF16723.5 AJW69789.1 - 0.039 14.0 0.4 0.17 12.0 0.0 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5065) Cnd1 PF12717.7 AJW69789.1 - 0.087 12.9 0.8 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FAM25 PF15825.5 AJW69789.1 - 0.33 11.3 1.2 2.3 8.6 0.2 2.4 1 1 1 2 2 2 0 FAM25 family DUF4692 PF15763.5 AJW69789.1 - 2.2 8.8 10.9 0.63 10.5 7.8 1.7 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SIR2 PF02146.17 AJW69790.1 - 2.2e-55 187.3 0.0 2.8e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 AJW69790.1 - 0.018 14.7 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain RNA_POL_M_15KD PF02150.16 AJW69790.1 - 0.022 14.6 1.4 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Smim3 PF17307.2 AJW69790.1 - 0.06 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 Lactamase_B_2 PF12706.7 AJW69791.1 - 1.6e-15 57.2 0.0 7.9e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AJW69791.1 - 1.6e-06 28.3 0.0 6.6e-06 26.3 0.0 1.9 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily NAD_binding_10 PF13460.6 AJW69791.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Lactamase_B_4 PF13691.6 AJW69791.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNase Z endonuclease Cucumo_coat PF00760.18 AJW69791.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Cucumovirus coat protein UPF0020 PF01170.18 AJW69792.1 - 2.7e-20 72.9 0.0 1.5e-19 70.5 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 AJW69792.1 - 4.8e-13 49.3 0.0 4.5e-12 46.2 0.0 2.1 2 1 0 2 2 2 1 DNA methylase Methyltransf_31 PF13847.6 AJW69792.1 - 2.3e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW69792.1 - 1.2e-06 29.1 0.0 2.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AJW69792.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 AJW69792.1 - 3.4e-05 23.3 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase AviRa PF11599.8 AJW69792.1 - 0.00034 20.2 0.0 0.024 14.1 0.0 2.3 1 1 1 2 2 2 1 RRNA methyltransferase AviRa MTS PF05175.14 AJW69792.1 - 0.00098 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AJW69792.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) THUMP PF02926.17 AJW69792.1 - 0.0024 18.0 0.5 0.0095 16.0 0.1 2.2 2 1 0 2 2 2 1 THUMP domain Methyltransf_5 PF01795.19 AJW69792.1 - 0.0025 17.4 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_11 PF08241.12 AJW69792.1 - 0.0061 17.2 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AJW69792.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MethyltransfD12 PF02086.15 AJW69792.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.8 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 AJW69792.1 - 0.029 14.0 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 AJW69792.1 - 0.044 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Pribosyltran_N PF13793.6 AJW69793.1 - 3.2e-26 91.5 0.6 6.9e-25 87.3 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 AJW69793.1 - 6.3e-16 58.3 1.0 9.9e-16 57.7 0.3 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 AJW69793.1 - 1.6e-13 51.1 3.6 6.7e-13 49.1 0.7 2.8 2 2 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 AJW69793.1 - 0.00034 20.1 0.0 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AJW69793.1 - 0.0015 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase Asp_Glu_race PF01177.22 AJW69793.1 - 0.017 15.0 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase MS_channel PF00924.18 AJW69794.1 - 2.3e-31 109.0 0.4 4.1e-31 108.1 0.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF1461 PF07314.11 AJW69794.1 - 0.18 11.7 1.8 0.37 10.7 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF2208 PF09973.9 AJW69794.1 - 0.4 10.3 7.0 0.032 13.9 1.8 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF1129 PF06570.11 AJW69794.1 - 2.5 7.5 5.4 0.56 9.6 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Sulf_transp PF04143.14 AJW69794.1 - 4.2 6.8 6.9 12 5.3 0.1 2.2 2 0 0 2 2 2 0 Sulphur transport Fer4_12 PF13353.6 AJW69795.1 - 0.00011 22.5 0.3 0.00025 21.3 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AJW69795.1 - 0.00019 21.6 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AJW69795.1 - 0.00029 21.3 0.1 0.002 18.5 0.1 2.4 2 1 0 2 2 2 1 Radical SAM superfamily RVT_connect PF06815.13 AJW69795.1 - 0.047 13.9 0.1 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase connection domain AA_permease_2 PF13520.6 AJW69797.1 - 2e-46 158.7 59.2 2.4e-46 158.4 59.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AJW69797.1 - 2.5e-40 138.5 50.4 3.7e-40 137.9 50.4 1.3 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AJW69797.1 - 3.9e-06 25.9 25.5 3.9e-06 25.9 25.5 2.7 1 1 1 3 3 3 1 Spore germination protein AA_permease_C PF13906.6 AJW69797.1 - 0.073 13.2 0.5 0.073 13.2 0.5 4.8 7 1 0 7 7 7 0 C-terminus of AA_permease DUF4536 PF15055.6 AJW69797.1 - 1.4 9.3 6.4 3.9 7.8 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) VIT1 PF01988.19 AJW69798.1 - 2e-55 188.0 0.6 2.3e-55 187.8 0.6 1.0 1 0 0 1 1 1 1 VIT family PGG PF13962.6 AJW69798.1 - 0.018 14.8 4.2 0.018 14.8 4.2 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF4271 PF14093.6 AJW69798.1 - 0.02 14.8 2.0 0.02 14.8 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Usp PF00582.26 AJW69799.1 - 8.2e-27 94.4 0.0 9.7e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF3880 PF12996.7 AJW69799.1 - 0.049 13.7 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) DnaJ PF00226.31 AJW69800.1 - 4.8e-10 39.4 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain FLgD_tudor PF13861.6 AJW69800.1 - 0.036 14.3 0.2 0.54 10.5 0.1 2.3 2 0 0 2 2 2 0 FlgD Tudor-like domain Urease_alpha PF00449.20 AJW69800.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain HAMP PF00672.25 AJW69801.1 - 1.6e-15 57.2 0.0 3.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 HAMP domain Guanylate_cyc PF00211.20 AJW69801.1 - 2.9e-13 49.9 0.3 6.7e-13 48.7 0.3 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain dCache_1 PF02743.18 AJW69801.1 - 3.4e-11 43.4 0.8 6.2e-11 42.6 0.8 1.6 1 1 0 1 1 1 1 Cache domain Copper-bind PF00127.20 AJW69802.1 - 1.2e-06 28.8 0.0 2.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Slp PF03843.13 AJW69802.1 - 0.02 14.3 0.4 0.051 12.9 0.0 1.8 3 0 0 3 3 3 0 Outer membrane lipoprotein Slp family Fer4 PF00037.27 AJW69803.1 - 2e-11 43.2 10.6 5.1e-07 29.3 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJW69803.1 - 6.9e-09 36.2 3.7 9.8e-09 35.7 3.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJW69803.1 - 3.5e-08 33.2 8.1 0.0013 18.7 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AJW69803.1 - 4.5e-08 33.1 1.8 6.4e-08 32.6 1.8 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJW69803.1 - 4.4e-06 26.8 4.1 1.8e-05 24.8 4.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AJW69803.1 - 1.5e-05 24.8 7.8 0.018 15.1 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJW69803.1 - 7.9e-05 23.1 4.2 0.12 12.9 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 AJW69803.1 - 0.00014 21.9 8.3 0.0054 16.8 9.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJW69803.1 - 0.00025 21.3 6.9 0.081 13.5 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AJW69803.1 - 0.00027 21.8 5.4 0.075 14.0 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 AJW69803.1 - 0.0013 19.5 11.2 0.097 13.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 AJW69803.1 - 0.0019 19.0 3.8 0.3 12.0 0.9 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJW69803.1 - 0.0052 17.2 5.8 0.048 14.1 5.8 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AJW69803.1 - 0.031 14.8 6.7 1 9.9 6.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJW69803.1 - 0.08 13.7 10.7 0.51 11.1 2.1 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AJW69803.1 - 0.7 10.1 10.3 1.8 8.8 3.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Aminotran_5 PF00266.19 AJW69804.1 - 8.6e-66 222.4 0.0 1e-65 222.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AJW69804.1 - 8.5e-09 35.0 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AJW69804.1 - 0.0025 17.1 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase YgbB PF02542.16 AJW69804.1 - 0.025 14.9 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 YgbB family AsnC_trans_reg PF01037.21 AJW69805.1 - 8.4e-08 32.1 0.1 9.3e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain phage_tail_N PF08400.10 AJW69805.1 - 0.054 13.5 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Cyclase PF04199.13 AJW69806.1 - 9.1e-31 106.9 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase DSPc PF00782.20 AJW69807.1 - 3e-16 59.4 0.0 4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AJW69807.1 - 1.7e-08 34.3 0.0 4.3e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 AJW69807.1 - 2.6e-06 27.6 0.0 3.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 AJW69807.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 AJW69807.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 AJW69807.1 - 0.021 14.8 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family GDH_N PF12466.8 AJW69807.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal RNA_pol_L_2 PF13656.6 AJW69811.1 - 5.6e-13 48.5 0.0 6.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TFIIS_C PF01096.18 AJW69812.1 - 2.6e-19 68.7 6.9 2.6e-19 68.7 6.9 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 AJW69812.1 - 2.7e-05 23.9 15.5 0.021 14.7 6.7 4.1 3 1 0 3 3 3 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 AJW69812.1 - 0.0033 17.4 11.1 0.014 15.4 2.1 2.7 1 1 1 2 2 2 2 Double zinc ribbon Elf1 PF05129.13 AJW69812.1 - 0.0077 16.2 4.8 0.36 10.9 0.1 2.2 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 AJW69812.1 - 0.021 14.7 14.9 3.6 7.6 0.5 4.1 3 1 0 3 3 3 0 zinc-ribbon domain Baculo_LEF5_C PF11792.8 AJW69812.1 - 0.049 13.3 0.9 0.049 13.3 0.9 3.1 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.10 AJW69812.1 - 0.1 12.8 11.7 6.1 7.0 0.0 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 AJW69812.1 - 0.1 12.4 16.3 1 9.2 6.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AJW69812.1 - 0.1 12.5 12.6 0.52 10.3 1.5 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Ribosomal_L44 PF00935.19 AJW69812.1 - 0.2 12.1 9.7 7.3 7.1 3.0 3.2 3 0 0 3 3 3 0 Ribosomal protein L44 UPF0547 PF10571.9 AJW69812.1 - 0.29 11.3 13.5 0.18 11.9 4.7 3.4 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 AJW69812.1 - 0.53 10.3 11.8 0.28 11.2 1.4 2.6 2 1 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 AJW69812.1 - 0.54 10.3 16.0 1.6 8.7 4.9 3.1 2 2 1 3 3 3 0 Transposase zinc-ribbon domain C1_1 PF00130.22 AJW69812.1 - 0.65 9.9 13.7 0.15 12.0 2.3 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.6 AJW69812.1 - 1.1 9.2 12.2 21 5.1 0.5 4.0 3 1 0 3 3 3 0 Nudix N-terminal zinc_ribbon_15 PF17032.5 AJW69812.1 - 1.2 9.9 13.3 1.6e+02 3.1 13.3 2.9 1 1 0 1 1 1 0 zinc-ribbon family Cytochrom_CIII PF02085.16 AJW69812.1 - 1.7 9.0 7.2 24 5.3 1.5 2.4 1 1 1 2 2 2 0 Class III cytochrome C family A2L_zn_ribbon PF08792.10 AJW69812.1 - 4 7.3 14.4 22 4.9 0.1 4.0 3 1 0 3 3 3 0 A2L zinc ribbon domain Rubredoxin_2 PF18073.1 AJW69812.1 - 4.1 7.2 21.1 2.7 7.8 0.5 3.9 4 0 0 4 4 4 0 Rubredoxin metal binding domain TackOD1 PF18551.1 AJW69812.1 - 4.1 7.0 10.5 1.2e+02 2.2 10.8 2.7 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 HypA PF01155.19 AJW69812.1 - 5.2 7.1 11.2 12 6.0 2.5 2.6 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_2 PF03107.16 AJW69812.1 - 5.3 7.5 13.7 15 6.0 5.1 2.9 2 1 0 2 2 2 0 C1 domain zinc_ribbon_13 PF09855.9 AJW69812.1 - 5.4 7.3 16.2 5.3 7.3 0.1 3.9 3 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Ribosomal_L33 PF00471.20 AJW69812.1 - 9.4 6.8 10.8 20 5.7 0.2 3.5 3 1 0 3 3 3 0 Ribosomal protein L33 PCNA_N PF00705.18 AJW69813.1 - 4.1e-19 68.5 0.0 7.5e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 AJW69813.1 - 9.1e-17 61.4 0.8 2.9e-15 56.5 0.0 2.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 AJW69813.1 - 1.6e-07 30.7 0.0 0.0013 17.9 0.0 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 AJW69813.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Rad9 Receptor_2B4 PF11465.8 AJW69813.1 - 0.056 13.7 0.1 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 AA_kinase PF00696.28 AJW69814.1 - 3.1e-53 180.8 0.8 3.1e-53 180.8 0.8 1.9 2 1 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 AJW69814.1 - 5.8e-21 74.0 3.3 1.5e-11 43.9 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AJW69814.1 - 9.1e-21 73.3 1.7 3.8e-09 36.1 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.6 AJW69814.1 - 0.0077 16.2 0.2 0.23 11.5 0.0 2.9 2 0 0 2 2 2 1 ACT domain FIST PF08495.10 AJW69814.1 - 0.028 14.4 0.0 0.12 12.4 0.0 2.1 1 1 0 1 1 1 0 FIST N domain RNA_pol_Rpb1_1 PF04997.12 AJW69814.1 - 0.046 13.0 2.3 0.1 11.9 2.3 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Syntaxin_2 PF14523.6 AJW69814.1 - 0.065 13.6 10.5 0.18 12.2 9.9 2.1 2 0 0 2 2 2 0 Syntaxin-like protein PD40 PF07676.12 AJW69815.1 - 0.031 14.2 0.4 7.8 6.6 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lipoprotein_15 PF03640.15 AJW69815.1 - 0.51 9.9 1.7 22 4.7 0.4 2.3 2 0 0 2 2 2 0 Secreted repeat of unknown function TP_methylase PF00590.20 AJW69816.1 - 4.9e-38 131.2 0.0 5.9e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1522 PF07482.11 AJW69816.1 - 0.043 14.1 0.0 0.83 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) tRNA-synt_1b PF00579.25 AJW69817.1 - 3.4e-40 138.2 0.1 4.4e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RsbU_N PF08673.10 AJW69818.1 - 0.024 14.7 0.1 0.028 14.5 0.1 1.3 1 1 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain zf-C2H2 PF00096.26 AJW69819.1 - 3.1e-09 36.8 5.5 0.00069 19.9 0.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJW69819.1 - 2.6e-08 34.0 7.7 0.00086 20.0 1.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 AJW69819.1 - 4.5e-05 22.9 0.4 0.042 13.4 0.0 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding zf-C2H2_6 PF13912.6 AJW69819.1 - 0.00018 21.4 1.7 0.00018 21.4 1.7 2.6 2 1 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 AJW69819.1 - 0.00038 21.2 5.7 0.0004 21.1 5.7 1.2 1 0 0 1 1 1 1 zinc-ribbon family zf-C2H2_11 PF16622.5 AJW69819.1 - 0.0015 18.3 0.8 0.61 9.9 0.0 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zinc_ribbon_2 PF13240.6 AJW69819.1 - 0.0028 17.3 3.0 0.12 12.1 0.1 2.6 2 1 0 2 2 2 1 zinc-ribbon domain zf-C2H2_3rep PF18868.1 AJW69819.1 - 0.003 18.2 2.4 0.0093 16.6 2.4 1.7 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Prok-RING_1 PF14446.6 AJW69819.1 - 0.0054 16.6 3.5 0.087 12.8 0.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-FPG_IleRS PF06827.14 AJW69819.1 - 0.0063 16.4 3.3 0.56 10.1 0.2 2.4 2 1 0 2 2 2 2 Zinc finger found in FPG and IleRS Ribosomal_S27e PF01667.17 AJW69819.1 - 0.01 15.5 0.5 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 A2L_zn_ribbon PF08792.10 AJW69819.1 - 0.014 15.1 1.5 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 AJW69819.1 - 0.02 14.9 7.4 0.041 13.9 0.9 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.6 AJW69819.1 - 0.025 14.5 2.4 0.025 14.5 2.4 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_C2H2_ZHX PF18387.1 AJW69819.1 - 0.029 14.0 3.0 0.24 11.0 0.3 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-ribbon_3 PF13248.6 AJW69819.1 - 0.033 13.6 3.9 0.24 10.9 0.1 2.4 3 0 0 3 3 2 0 zinc-ribbon domain DZR PF12773.7 AJW69819.1 - 0.042 13.9 5.7 0.079 13.0 5.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.14 AJW69819.1 - 0.047 13.7 3.1 0.11 12.4 3.0 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid RNA_POL_M_15KD PF02150.16 AJW69819.1 - 0.048 13.5 3.2 0.69 9.8 0.7 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-Sec23_Sec24 PF04810.15 AJW69819.1 - 0.053 13.6 0.9 0.42 10.7 0.9 2.1 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 AJW69819.1 - 0.054 13.8 7.8 1.6 9.1 1.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 AJW69819.1 - 0.057 13.3 5.5 0.62 10.0 0.1 2.5 2 1 1 3 3 3 0 zinc-ribbon domain zf_UBZ PF18439.1 AJW69819.1 - 0.074 12.7 2.7 0.67 9.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 AJW69819.1 - 0.078 13.1 6.5 0.12 12.5 3.1 2.0 1 1 1 2 2 2 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 AJW69819.1 - 0.086 13.0 6.8 0.74 10.0 6.8 2.1 1 1 0 1 1 1 0 Zinc ribbon domain UPF0547 PF10571.9 AJW69819.1 - 0.12 12.5 5.1 0.73 10.0 0.1 2.5 3 0 0 3 3 2 0 Uncharacterised protein family UPF0547 Gal_GalNac_35kD PF17337.2 AJW69819.1 - 0.12 12.4 2.3 0.13 12.3 2.3 1.0 1 0 0 1 1 1 0 Galactose-inhibitable lectin 35 kDa subunit DUF983 PF06170.12 AJW69819.1 - 0.14 12.6 1.9 1.5 9.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-Mss51 PF13824.6 AJW69819.1 - 0.26 11.4 5.3 0.2 11.8 1.5 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF35_N PF12172.8 AJW69819.1 - 0.33 10.9 2.2 4.1 7.4 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-H2C2_2 PF13465.6 AJW69819.1 - 6.8 7.3 11.6 3.9 8.1 2.9 3.0 3 0 0 3 3 3 0 Zinc-finger double domain DegT_DnrJ_EryC1 PF01041.17 AJW69821.1 - 3.8e-115 385.0 0.1 4.3e-115 384.9 0.1 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AJW69821.1 - 1.3e-10 41.1 0.1 2e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AJW69821.1 - 1.4e-08 34.1 2.6 3.9e-08 32.7 0.5 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJW69821.1 - 9.9e-08 30.9 0.5 1.6e-07 30.2 0.3 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AJW69821.1 - 6.4e-06 25.7 0.1 1.6e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase ComK PF06338.11 AJW69821.1 - 0.00054 19.6 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 ComK protein OKR_DC_1 PF01276.20 AJW69821.1 - 0.0082 14.9 0.1 0.014 14.1 0.1 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain PA28_alpha PF02251.18 AJW69821.1 - 0.012 15.7 0.8 4.7 7.3 0.3 2.6 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit MtrA PF04208.14 AJW69822.1 - 1.1e-24 87.0 0.1 1.4e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A Pox_G5 PF04599.12 AJW69822.1 - 0.0098 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus G5 protein dUTPase_2 PF08761.11 AJW69823.1 - 4.2e-19 69.3 6.0 6.3e-14 52.5 0.3 2.0 1 1 1 2 2 2 2 dUTPase PRA-PH PF01503.17 AJW69823.1 - 0.00025 21.4 0.0 0.00032 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase DUF550 PF04447.12 AJW69823.1 - 0.082 13.0 1.2 0.23 11.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF550) PfkB PF00294.24 AJW69824.1 - 1.8e-24 86.6 0.1 2.9e-24 85.9 0.1 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AJW69824.1 - 8.5e-05 22.0 0.2 0.00019 20.9 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 AJW69824.1 - 0.002 17.7 0.2 1.1 8.7 0.1 2.4 2 1 0 2 2 2 2 Carbohydrate kinase OstA_2 PF13100.6 AJW69824.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 OstA-like protein Pro_isomerase PF00160.21 AJW69829.1 - 1.3e-51 175.0 0.1 1.5e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HTH_23 PF13384.6 AJW69830.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain CC190 PF15768.5 AJW69830.1 - 0.0091 16.1 0.1 0.0097 16.0 0.1 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 190 DUF5388 PF17363.2 AJW69830.1 - 0.06 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5388) GntR PF00392.21 AJW69830.1 - 0.088 12.5 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.10 AJW69830.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF3450 PF11932.8 AJW69832.1 - 0.00044 19.6 1.8 0.00057 19.3 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF2730 PF10805.8 AJW69832.1 - 0.0032 17.5 1.6 0.0072 16.4 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Yuri_gagarin PF15934.5 AJW69832.1 - 0.0043 16.9 0.9 0.0048 16.8 0.9 1.1 1 0 0 1 1 1 1 Yuri gagarin VGPC1_C PF16799.5 AJW69832.1 - 0.069 13.1 4.0 0.099 12.6 3.0 1.7 1 1 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF641 PF04859.12 AJW69832.1 - 0.12 12.8 3.1 0.21 11.9 3.1 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Fzo_mitofusin PF04799.13 AJW69832.1 - 0.13 11.8 4.0 0.16 11.5 4.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region MLANA PF14991.6 AJW69832.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A FlaC_arch PF05377.11 AJW69832.1 - 0.56 10.6 8.0 2.7 8.5 1.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 AJW69832.1 - 3.2 7.0 8.1 5.1 6.4 8.1 1.3 1 1 0 1 1 1 0 FAM76 protein FMN_red PF03358.15 AJW69833.1 - 5.8e-23 81.3 0.0 7.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AJW69833.1 - 4.4e-08 33.1 0.0 5.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold SAPI PF16560.5 AJW69833.1 - 0.0044 16.6 0.1 0.005 16.4 0.1 1.2 1 0 0 1 1 1 1 Putative mobile pathogenicity island DUF2283 PF10049.9 AJW69833.1 - 0.0081 16.4 0.1 0.87 9.9 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2283) Nitroreductase PF00881.24 AJW69834.1 - 2.5e-27 96.0 0.0 4.2e-27 95.3 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AJW69834.1 - 0.0011 18.5 0.6 0.21 11.1 0.0 2.9 1 1 1 2 2 2 2 Putative TM nitroreductase DUF5067 PF16729.5 AJW69835.1 - 0.019 14.9 0.2 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) DUF4878 PF12870.7 AJW69835.1 - 0.05 13.9 0.4 0.085 13.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) CopD PF05425.13 AJW69836.1 - 7.8e-15 55.2 0.7 7.8e-15 55.2 0.7 1.5 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 AJW69836.1 - 0.00012 22.2 5.9 0.00016 21.8 5.9 1.1 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) UPF0093 PF03653.13 AJW69836.1 - 0.0029 17.8 7.5 0.0069 16.6 7.5 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0093) Aa_trans PF01490.18 AJW69836.1 - 0.0076 15.0 2.3 0.0076 15.0 2.3 2.0 1 1 0 2 2 2 1 Transmembrane amino acid transporter protein SieB PF14163.6 AJW69836.1 - 0.013 15.0 8.9 0.022 14.3 2.8 2.4 2 1 0 2 2 2 0 Super-infection exclusion protein B UPF0154 PF03672.13 AJW69836.1 - 0.023 14.7 1.4 0.082 12.9 0.4 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0154) PEMT PF04191.13 AJW69836.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.1 2 1 0 2 2 2 0 Phospholipid methyltransferase DUF4149 PF13664.6 AJW69836.1 - 0.15 12.4 6.2 0.064 13.6 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Urate_ox_N PF06181.11 AJW69836.1 - 0.22 10.9 4.5 0.063 12.6 0.8 1.8 1 1 0 2 2 2 0 Urate oxidase N-terminal Brr6_like_C_C PF10104.9 AJW69836.1 - 1.4 8.7 5.0 0.3 10.9 0.7 2.1 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DHHC PF01529.20 AJW69836.1 - 7.8 6.6 6.1 4.5 7.4 0.8 2.2 2 1 0 2 2 2 0 DHHC palmitoyltransferase RTC PF01137.21 AJW69837.1 - 4.4e-75 251.7 0.1 5.1e-75 251.5 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase GCD14 PF08704.10 AJW69837.1 - 0.022 14.4 0.0 5.5 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit SPATA1_C PF15743.5 AJW69837.1 - 0.1 12.7 0.8 0.18 11.8 0.8 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus CTP_transf_like PF01467.26 AJW69838.1 - 9.7e-13 48.5 0.1 7.3e-12 45.7 0.1 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like Aminotran_5 PF00266.19 AJW69839.1 - 4.6e-32 111.4 0.0 5.6e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AJW69839.1 - 0.0038 15.8 0.0 0.0056 15.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FKBP26_C PF18046.1 AJW69840.1 - 7.8e-12 45.1 1.2 2.2e-11 43.7 1.2 1.8 1 0 0 1 1 1 1 FKBP26_C-terminal FKBP_C PF00254.28 AJW69840.1 - 4.5e-11 42.9 0.1 2.4e-10 40.6 0.1 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase CAP_GLY PF01302.25 AJW69840.1 - 0.0021 18.0 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Fe-ADH_2 PF13685.6 AJW69841.1 - 5.6e-71 239.2 0.9 7.3e-71 238.8 0.9 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AJW69841.1 - 5.9e-23 81.3 0.2 5.8e-21 74.7 0.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AJW69841.1 - 0.00057 19.1 0.1 0.0083 15.3 0.1 2.4 1 1 0 1 1 1 1 3-dehydroquinate synthase Proteasome PF00227.26 AJW69842.1 - 6.9e-51 172.4 0.2 7.9e-51 172.2 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Beta-Casp PF10996.8 AJW69843.1 - 2e-22 79.6 0.0 3.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain KH_7 PF17214.3 AJW69843.1 - 1e-21 76.7 1.5 7.5e-21 73.9 0.7 2.7 3 0 0 3 3 3 1 KH domain RMMBL PF07521.12 AJW69843.1 - 1.1e-15 57.2 0.0 2.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AJW69843.1 - 3.4e-13 49.5 0.0 6.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 AJW69843.1 - 3.4e-12 46.8 0.2 9.3e-11 42.1 0.2 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJW69843.1 - 6.5e-10 38.9 0.0 2.4e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AJW69843.1 - 0.033 14.1 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain SepF PF04472.12 AJW69844.1 - 1e-12 48.1 1.0 1.2e-12 48.0 1.0 1.0 1 0 0 1 1 1 1 Cell division protein SepF H_kinase_N PF12282.8 AJW69844.1 - 0.0095 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal transduction histidine kinase Herpes_IE68 PF02479.16 AJW69844.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus immediate early protein SporV_AA PF12164.8 AJW69844.1 - 0.023 15.0 0.6 0.034 14.5 0.6 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AA Tsc35 PF15079.6 AJW69844.1 - 0.081 12.5 0.2 0.091 12.3 0.2 1.1 1 0 0 1 1 1 0 Testis-specific protein 35 NFACT-R_2 PF18297.1 AJW69845.1 - 3.4e-23 81.8 0.1 7.2e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain ThiI PF02568.14 AJW69845.1 - 5.6e-12 45.6 0.0 1.5e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 AJW69845.1 - 7.4e-09 34.9 0.1 4.2e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AJW69845.1 - 0.015 14.8 0.1 0.037 13.5 0.1 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NFACT-R_1 PF05670.13 AJW69845.1 - 0.038 14.6 0.0 0.074 13.7 0.0 1.4 1 0 0 1 1 1 0 NFACT protein RNA binding domain Asn_synthase PF00733.21 AJW69845.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.17 AJW69845.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Peptidase_M24 PF00557.24 AJW69846.1 - 1.3e-56 191.7 0.0 1.6e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AJW69846.1 - 4.4e-12 46.8 0.0 7.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Phage_HK97_TLTM PF06120.11 AJW69846.1 - 0.99 8.5 4.1 0.43 9.7 1.0 1.8 2 0 0 2 2 2 0 Tail length tape measure protein Methyltransf_25 PF13649.6 AJW69848.1 - 8.2e-18 64.9 0.0 1.7e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJW69848.1 - 9.5e-17 61.1 0.2 2.7e-16 59.6 0.1 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AJW69848.1 - 2.1e-16 60.1 0.1 3.5e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJW69848.1 - 1.7e-15 57.4 0.0 3.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW69848.1 - 3.1e-13 49.9 0.0 5.3e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW69848.1 - 1.6e-11 44.8 0.0 3.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJW69848.1 - 2.3e-06 27.3 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AJW69848.1 - 1.2e-05 25.0 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 AJW69848.1 - 3.6e-05 23.2 0.0 7.1e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 AJW69848.1 - 0.00014 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 AJW69848.1 - 0.00068 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 AJW69848.1 - 0.0028 17.2 0.3 0.017 14.6 0.1 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.13 AJW69848.1 - 0.004 16.6 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 AJW69848.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 AJW69848.1 - 0.021 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 AJW69848.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Carb_anhydrase PF00194.21 AJW69849.1 - 0.012 15.2 0.2 0.013 15.1 0.2 1.0 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase DUF2630 PF10944.8 AJW69849.1 - 0.094 13.2 0.7 0.12 12.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DFP PF04127.15 AJW69850.1 - 2.8e-55 187.0 3.6 5.3e-53 179.6 1.3 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AJW69850.1 - 1e-35 122.8 2.1 1.5e-35 122.3 0.2 2.1 2 1 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.6 AJW69850.1 - 0.0009 19.6 2.8 0.16 12.4 0.1 3.3 4 0 0 4 4 4 2 Putative NAD(P)-binding F420_oxidored PF03807.17 AJW69850.1 - 0.016 15.8 0.1 0.065 13.8 0.1 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 AJW69850.1 - 0.031 14.2 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus Shikimate_DH PF01488.20 AJW69850.1 - 0.065 13.3 1.1 0.15 12.1 0.1 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pantoate_transf PF02548.15 AJW69851.1 - 4.6e-107 357.2 1.8 5.2e-107 357.0 1.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 AJW69851.1 - 0.00014 21.4 0.2 0.00043 19.8 0.2 1.9 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 AJW69851.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase PPS_PS PF02006.16 AJW69852.1 - 3.6e-71 238.3 4.0 4.5e-71 238.0 4.0 1.1 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase HicB_lk_antitox PF15919.5 AJW69852.1 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Orexin_rec2 PF03827.13 AJW69852.1 - 0.14 12.1 0.2 28 4.8 0.1 2.4 2 0 0 2 2 2 0 Orexin receptor type 2 GHMP_kinases_N PF00288.26 AJW69853.1 - 1.8e-12 47.3 0.1 3.4e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain mTERF PF02536.14 AJW69853.1 - 0.0037 16.2 0.3 0.0054 15.7 0.3 1.1 1 0 0 1 1 1 1 mTERF PhoU PF01895.19 AJW69854.1 - 3.7e-08 33.7 5.5 2.8e-06 27.7 2.1 2.6 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 AJW69854.1 - 8.8e-06 25.5 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin NUDIX PF00293.28 AJW69855.1 - 8.3e-18 64.7 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain TetR_C_10 PF16295.5 AJW69855.1 - 0.028 14.7 0.1 0.046 14.0 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_24 PF13412.6 AJW69856.1 - 2.3e-19 68.7 9.5 2.2e-09 36.7 2.1 2.6 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJW69856.1 - 2.5e-18 65.6 1.4 7.9e-10 38.4 0.1 2.3 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 AJW69856.1 - 6.4e-06 26.0 0.3 0.0044 16.9 0.1 2.7 2 0 0 2 2 2 2 HTH domain MarR PF01047.22 AJW69856.1 - 9.2e-06 25.5 2.1 0.00061 19.7 0.2 2.9 3 0 0 3 3 3 1 MarR family HTH_Mga PF08280.11 AJW69856.1 - 3.1e-05 23.9 4.3 0.00016 21.6 1.1 2.9 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain MarR_2 PF12802.7 AJW69856.1 - 3.2e-05 23.7 0.0 0.043 13.7 0.0 2.3 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 AJW69856.1 - 3.8e-05 23.5 0.0 0.021 14.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Trp_repressor PF01371.19 AJW69856.1 - 0.002 18.2 1.0 0.0067 16.5 0.2 2.3 2 0 0 2 2 2 1 Trp repressor protein HTH_28 PF13518.6 AJW69856.1 - 0.0089 16.1 0.0 0.87 9.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Mga PF05043.13 AJW69856.1 - 0.0098 16.5 1.8 0.17 12.5 0.1 3.1 3 1 0 3 3 3 1 Mga helix-turn-helix domain GerE PF00196.19 AJW69856.1 - 0.011 15.3 3.8 0.16 11.5 0.2 3.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AJW69856.1 - 0.014 15.1 0.0 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_DeoR PF08220.12 AJW69856.1 - 0.029 14.1 0.2 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 AJW69856.1 - 0.055 13.4 0.3 3.5 7.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_29 PF13551.6 AJW69856.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Rnk_N PF14760.6 AJW69856.1 - 0.092 13.2 0.6 14 6.3 0.1 2.5 2 0 0 2 2 2 0 Rnk N-terminus HTH_41 PF14502.6 AJW69856.1 - 0.1 12.3 1.5 4.1 7.2 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_36 PF13730.6 AJW69856.1 - 0.12 12.4 0.2 0.34 10.9 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain RuvB_C PF05491.13 AJW69856.1 - 0.58 10.1 4.4 0.97 9.4 0.2 2.8 3 1 0 3 3 3 0 RuvB C-terminal winged helix domain MacB_PCD PF12704.7 AJW69857.1 - 1.5e-16 61.3 3.2 2.5e-16 60.6 3.2 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 AJW69857.1 - 1.4e-14 54.4 1.6 1.4e-14 54.4 1.6 2.2 2 0 0 2 2 2 1 FtsX-like permease family ABC_tran PF00005.27 AJW69858.1 - 1.6e-19 70.8 0.0 2.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AJW69858.1 - 7e-05 22.4 0.3 0.00011 21.7 0.2 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AJW69858.1 - 0.0085 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain IL23 PF16649.5 AJW69858.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Interleukin 23 subunit alpha CRISPR_Cas9_WED PF18061.1 AJW69858.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain NPCBM_assoc PF10633.9 AJW69859.1 - 0.00046 20.4 0.9 1.3 9.3 0.0 4.2 3 2 1 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF11 PF01345.18 AJW69859.1 - 0.086 13.1 2.1 1.7 9.0 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF11 DUF4832 PF16116.5 AJW69859.1 - 0.099 12.5 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) Spc7 PF08317.11 AJW69860.1 - 0.00037 19.5 8.0 0.00046 19.2 8.0 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein HemX PF04375.14 AJW69860.1 - 0.0004 19.8 2.5 0.00047 19.6 2.5 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase SOAR PF16533.5 AJW69860.1 - 0.001 19.0 3.3 0.0013 18.7 3.3 1.2 1 0 0 1 1 1 1 STIM1 Orai1-activating region BAR PF03114.18 AJW69860.1 - 0.0026 17.5 1.2 0.0027 17.4 1.2 1.0 1 0 0 1 1 1 1 BAR domain FapA PF03961.13 AJW69860.1 - 0.0066 15.1 5.3 0.0074 14.9 5.3 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF1043 PF06295.12 AJW69860.1 - 0.019 15.0 5.4 0.17 11.9 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF948 PF06103.11 AJW69860.1 - 0.019 15.2 5.5 0.044 14.0 5.6 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FixH PF05751.11 AJW69860.1 - 0.023 14.7 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 FixH MacB_PCD PF12704.7 AJW69860.1 - 0.039 14.3 0.0 0.042 14.2 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain CorA PF01544.18 AJW69860.1 - 0.045 13.1 4.9 0.065 12.5 4.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Allexi_40kDa PF05549.11 AJW69860.1 - 0.055 13.0 2.4 0.058 12.9 2.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Stn1 PF10451.9 AJW69860.1 - 0.08 11.9 3.3 0.2 10.6 3.3 1.7 1 1 0 1 1 1 0 Telomere regulation protein Stn1 XhlA PF10779.9 AJW69860.1 - 0.084 13.1 11.9 0.11 12.7 1.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF668 PF05003.12 AJW69860.1 - 0.099 13.1 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF668) AI-2E_transport PF01594.16 AJW69860.1 - 0.15 11.1 0.2 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 AI-2E family transporter ISG65-75 PF11727.8 AJW69860.1 - 0.18 11.0 3.8 0.21 10.8 3.8 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein CdvA PF18822.1 AJW69860.1 - 0.2 11.5 10.9 0.23 11.3 0.7 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain COG2 PF06148.11 AJW69860.1 - 0.22 11.6 6.1 3 7.9 5.9 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 AJW69860.1 - 0.4 11.3 6.3 2.2 8.9 5.0 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMPIT PF07851.13 AJW69860.1 - 0.68 9.1 4.4 0.82 8.9 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 AJW69860.1 - 0.81 8.9 11.2 0.85 8.9 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3040 PF11239.8 AJW69860.1 - 1.9 8.8 4.9 7.3 6.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Atg14 PF10186.9 AJW69860.1 - 2.4 7.2 9.3 3.7 6.5 9.3 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_holin_2_3 PF16080.5 AJW69861.1 - 0.0048 16.6 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 1 Bacteriophage holin family HP1 SPP PF06550.11 AJW69861.1 - 0.019 14.4 0.4 0.022 14.2 0.4 1.0 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease DUF1129 PF06570.11 AJW69862.1 - 0.088 12.3 0.0 0.094 12.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ABC1 PF03109.16 AJW69863.1 - 2.4e-24 85.8 0.1 7.8e-24 84.1 0.0 1.9 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 AJW69863.1 - 0.015 14.6 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein kinase domain DUF4795 PF16043.5 AJW69863.1 - 0.032 13.9 0.2 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) APH PF01636.23 AJW69863.1 - 0.078 12.9 0.0 0.22 11.4 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSP20 PF00011.21 AJW69864.1 - 3.4e-11 43.2 0.4 4.2e-11 42.9 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AJW69864.1 - 1.5e-09 37.3 0.0 6.6e-09 35.2 0.0 2.1 2 1 0 2 2 2 1 HSP20-like domain found in ArsA GUCT PF08152.12 AJW69864.1 - 0.14 12.5 0.1 0.3 11.4 0.1 1.7 1 1 0 1 1 1 0 GUCT (NUC152) domain RHH_5 PF07878.11 AJW69866.1 - 0.062 13.2 0.3 0.12 12.3 0.3 1.7 1 1 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 TrmB PF01978.19 AJW69868.1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.11 AJW69868.1 - 0.07 13.0 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_5 PF01022.20 AJW69868.1 - 0.087 12.7 0.4 0.15 11.9 0.4 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Intron_maturas2 PF01348.21 AJW69869.1 - 0.0012 18.8 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 Type II intron maturase Thymidylate_kin PF02223.17 AJW69870.1 - 2.4e-37 128.4 0.6 2.7e-37 128.2 0.6 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 AJW69870.1 - 0.012 15.5 4.5 0.11 12.3 4.5 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase PutA_N PF18083.1 AJW69870.1 - 0.055 13.5 0.3 0.18 11.9 0.0 1.9 2 1 0 2 2 2 0 Proline utilization A N-terminal domain RNase_J_C PF17770.1 AJW69870.1 - 0.69 11.0 5.2 1.3 10.1 2.7 2.3 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DUF2183 PF09949.9 AJW69870.1 - 0.99 9.8 4.3 0.79 10.1 1.2 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) HD PF01966.22 AJW69871.1 - 1.9e-16 60.4 0.3 3.9e-16 59.4 0.3 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AJW69871.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 HDOD domain AA_kinase PF00696.28 AJW69872.1 - 2e-31 109.4 1.2 3e-31 108.9 1.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family DUF4307 PF14155.6 AJW69874.1 - 0.027 14.3 0.2 0.28 11.0 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4307) LGT PF01790.18 AJW69875.1 - 0.031 13.5 0.6 0.031 13.5 0.6 1.0 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase Cas_Cas4 PF01930.17 AJW69876.1 - 0.00028 21.0 1.0 0.00053 20.1 1.0 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 AJW69876.1 - 0.015 15.2 0.8 1.7 8.5 0.1 2.1 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF2207 PF09972.9 AJW69877.1 - 8.6 5.0 7.1 9.6 4.8 7.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TraG_N PF07916.11 AJW69877.1 - 9.7 4.9 7.0 11 4.8 7.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region vATP-synt_AC39 PF01992.16 AJW69878.1 - 5.1e-53 180.7 9.5 6.6e-53 180.4 9.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF5126 PF17166.4 AJW69878.1 - 0.054 13.4 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) MutS_III PF05192.18 AJW69878.1 - 0.55 10.4 3.2 1.3 9.2 3.2 1.7 1 1 0 1 1 1 0 MutS domain III Ammonium_transp PF00909.21 AJW69880.1 - 4.2e-109 364.9 35.5 9.7e-109 363.7 35.5 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family Rhodanese PF00581.20 AJW69881.1 - 1.2e-39 135.1 0.1 4.8e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain GOLD_2 PF13897.6 AJW69882.1 - 0.14 12.7 3.3 3.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking V_ATPase_I PF01496.19 AJW69883.1 - 8.8e-27 93.4 14.8 6.6e-22 77.3 0.1 3.3 3 1 0 3 3 3 3 V-type ATPase 116kDa subunit family RasGEF_N_2 PF14663.6 AJW69883.1 - 0.041 14.3 0.1 1.6 9.2 0.0 2.8 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1931 PF09123.11 AJW69883.1 - 0.076 13.1 0.5 0.21 11.7 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Kri1 PF05178.12 AJW69883.1 - 0.1 13.2 5.7 1.8 9.2 0.4 2.7 2 1 0 2 2 2 0 KRI1-like family DivIVA PF05103.13 AJW69883.1 - 0.16 12.0 2.1 0.53 10.4 0.5 2.1 2 0 0 2 2 2 0 DivIVA protein Spore_GerAC PF05504.11 AJW69883.1 - 0.8 9.9 4.7 0.56 10.4 0.3 2.3 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal CCDC-167 PF15188.6 AJW69883.1 - 0.96 9.8 7.7 36 4.8 0.5 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 V-SNARE PF05008.15 AJW69883.1 - 5.4 7.5 8.3 12 6.3 1.2 3.4 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Swi5 PF07061.11 AJW69883.1 - 5.7 7.1 9.2 11 6.2 1.2 2.5 2 0 0 2 2 2 0 Swi5 vATP-synt_E PF01991.18 AJW69884.1 - 8.5e-17 61.2 7.7 6e-16 58.5 5.4 2.6 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit Flu_PB1 PF00602.17 AJW69884.1 - 0.022 12.9 0.6 0.045 11.9 0.3 1.6 2 0 0 2 2 2 0 Influenza RNA-dependent RNA polymerase subunit PB1 TROVE PF05731.11 AJW69884.1 - 0.045 12.8 0.1 0.059 12.4 0.1 1.1 1 0 0 1 1 1 0 TROVE domain ParB PF08775.10 AJW69884.1 - 0.083 13.4 3.4 0.11 13.0 2.4 1.7 1 1 0 1 1 1 0 ParB family Hamartin PF04388.12 AJW69884.1 - 0.13 10.9 0.8 0.16 10.6 0.8 1.0 1 0 0 1 1 1 0 Hamartin protein CBP_BcsQ PF06564.12 AJW69884.1 - 0.14 11.7 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ YkyA PF10368.9 AJW69884.1 - 0.74 9.5 8.4 1.5 8.4 6.8 1.9 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF5446 PF17522.2 AJW69884.1 - 1.3 9.2 4.7 0.73 10.0 1.1 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5446) ATP-synt_ab PF00006.25 AJW69885.1 - 9.4e-94 313.0 0.0 1.3e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 AJW69885.1 - 3.6e-41 139.8 0.0 6.5e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 AJW69885.1 - 4.7e-14 52.7 0.3 1.1e-13 51.5 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 AJW69885.1 - 0.032 14.5 0.2 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 AJW69885.1 - 0.11 11.1 0.2 0.18 10.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ATP-synt_ab PF00006.25 AJW69886.1 - 7.9e-70 234.8 0.0 1.1e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AJW69886.1 - 7.9e-12 45.5 1.9 1.9e-11 44.3 1.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AJW69886.1 - 0.00028 21.0 1.0 0.0014 18.7 0.5 2.3 2 0 0 2 2 2 1 HAS barrel domain T3SS_ATPase_C PF18269.1 AJW69886.1 - 0.14 12.0 0.6 7.2 6.5 0.1 2.6 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain ATP-synt_D PF01813.17 AJW69887.1 - 3.2e-48 164.2 6.5 3.6e-48 164.0 6.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit D STAT_alpha PF01017.20 AJW69887.1 - 0.055 13.4 2.2 0.27 11.1 0.2 2.3 2 0 0 2 2 2 0 STAT protein, all-alpha domain PerC PF06069.11 AJW69887.1 - 0.074 13.3 0.1 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 PerC transcriptional activator RICH PF05062.12 AJW69888.1 - 0.01 16.2 2.4 0.066 13.6 0.7 2.0 1 1 1 2 2 2 0 RICH domain RNase_J_C PF17770.1 AJW69888.1 - 0.041 14.9 0.3 0.046 14.8 0.3 1.0 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain ATP-synt_C PF00137.21 AJW69889.1 - 1.6e-16 60.4 16.0 1.6e-16 60.4 16.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PyrI PF01948.18 AJW69890.1 - 2e-31 108.1 2.2 3e-31 107.5 2.2 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 AJW69890.1 - 1.9e-14 53.3 1.9 5.1e-14 51.9 1.9 1.7 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1936 PF09151.10 AJW69890.1 - 0.05 13.5 0.4 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) OTCace_N PF02729.21 AJW69891.1 - 7.6e-41 139.6 0.0 1.2e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AJW69891.1 - 3.6e-30 105.1 0.0 5.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LON_substr_bdg PF02190.16 AJW69892.1 - 5.7e-15 55.8 0.1 7.4e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain SLBP_RNA_bind PF15247.6 AJW69892.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain Cdc6_C PF09079.11 AJW69894.1 - 5.9e-08 32.6 0.0 1.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 AJW69894.1 - 1.1e-07 32.4 0.2 5.3e-06 26.9 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AJW69894.1 - 4.1e-07 30.5 0.0 1.3e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AJW69894.1 - 4.5e-05 23.5 3.5 0.00069 19.6 2.4 2.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AJW69894.1 - 0.00011 22.5 0.0 0.00032 21.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 AJW69894.1 - 0.0033 16.6 0.0 0.024 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 AJW69894.1 - 0.0034 17.9 0.0 0.025 15.1 0.0 2.4 3 0 0 3 3 2 1 ABC transporter AAA_23 PF13476.6 AJW69894.1 - 0.0064 17.0 1.2 0.027 15.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 AJW69894.1 - 0.0072 15.5 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 AJW69894.1 - 0.016 15.6 0.0 0.44 11.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 AJW69894.1 - 0.031 14.0 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PAS_6 PF08348.11 AJW69894.1 - 0.037 13.9 0.8 2 8.3 0.1 3.1 3 0 0 3 3 3 0 YheO-like PAS domain AAA_assoc_2 PF16193.5 AJW69894.1 - 0.066 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 AJW69894.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AJW69894.1 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NTPase OST-HTH PF12872.7 AJW69894.1 - 0.095 12.5 0.0 0.44 10.4 0.0 2.2 1 0 0 1 1 1 0 OST-HTH/LOTUS domain NACHT PF05729.12 AJW69894.1 - 0.1 12.5 0.1 0.53 10.2 0.1 2.2 2 1 0 2 2 2 0 NACHT domain Cation_efflux PF01545.21 AJW69895.1 - 2.7e-17 63.2 13.7 1.4e-15 57.6 13.7 2.0 1 1 0 1 1 1 1 Cation efflux family TetR_C_11 PF16859.5 AJW69896.1 - 0.00025 21.3 0.3 19 5.6 0.0 4.7 3 2 2 5 5 5 2 Tetracyclin repressor-like, C-terminal domain Bep_C_terminal PF17841.1 AJW69896.1 - 0.00082 19.5 21.8 0.93 9.7 0.1 6.2 3 2 4 7 7 7 2 BID domain of Bartonella effector protein (Bep) MethyTransf_Reg PF10119.9 AJW69896.1 - 0.0042 17.8 13.0 3.5 8.4 0.0 5.5 4 2 1 5 5 5 2 Predicted methyltransferase regulatory domain TetR_C_28 PF17937.1 AJW69896.1 - 0.017 15.5 15.1 0.074 13.5 0.5 5.5 3 2 2 5 5 5 0 Tetracyclin repressor-like, C-terminal domain SATase_N PF06426.14 AJW69896.1 - 0.26 11.7 5.3 20 5.6 0.1 4.3 3 2 2 5 5 5 0 Serine acetyltransferase, N-terminal HD_assoc PF13286.6 AJW69896.1 - 1.8 9.1 20.8 0.42 11.2 0.8 4.9 4 2 1 5 5 5 0 Phosphohydrolase-associated domain Sortilin-Vps10 PF15902.5 AJW69897.1 - 1.1e-08 34.3 0.0 8.1e-08 31.5 0.0 1.9 1 1 1 2 2 2 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 AJW69897.1 - 7.9e-08 31.9 0.9 3.2e-06 26.6 0.2 2.3 1 1 1 2 2 2 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 AJW69897.1 - 0.0011 18.7 16.9 0.22 11.7 0.2 4.8 4 0 0 4 4 4 2 BNR/Asp-box repeat Reg_prop PF07494.11 AJW69897.1 - 0.043 14.0 0.0 26 5.5 0.0 4.1 5 0 0 5 5 5 0 Two component regulator propeller SBBP PF06739.11 AJW69897.1 - 0.044 13.8 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Beta-propeller repeat DUF4185 PF13810.6 AJW69897.1 - 0.083 12.1 0.6 6.6 5.9 0.0 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4185) DUF3029 PF11230.8 AJW69899.1 - 0.14 10.5 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Cation_efflux PF01545.21 AJW69900.1 - 4.5e-40 137.5 25.5 5.9e-40 137.1 25.5 1.1 1 0 0 1 1 1 1 Cation efflux family SGL PF08450.12 AJW69901.1 - 1.1e-10 41.6 0.4 0.078 12.6 0.0 4.9 2 1 3 5 5 5 4 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AJW69901.1 - 2.8e-05 23.9 0.5 0.018 15.1 0.0 3.9 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.11 AJW69901.1 - 0.0014 18.6 9.7 8.6 7.0 0.0 5.8 5 1 0 5 5 5 2 Two component regulator propeller Peptidase_C69 PF03577.15 AJW69901.1 - 0.019 13.9 1.6 0.052 12.5 0.4 2.2 2 0 0 2 2 2 0 Peptidase family C69 HTH_24 PF13412.6 AJW69902.1 - 2.9e-12 46.0 0.3 7.5e-08 31.8 0.1 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AJW69902.1 - 3.1e-06 27.0 0.2 0.00097 19.0 0.1 2.6 2 1 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AJW69902.1 - 0.00014 21.6 0.0 0.0053 16.5 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AJW69902.1 - 0.0005 19.9 0.0 0.09 12.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family FUR PF01475.19 AJW69902.1 - 0.00063 19.9 0.1 0.0018 18.4 0.0 1.8 1 1 1 2 2 2 1 Ferric uptake regulator family HTH_20 PF12840.7 AJW69902.1 - 0.0013 18.7 0.0 0.0084 16.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AJW69902.1 - 0.011 15.6 0.0 1.3 8.9 0.0 2.9 3 1 1 4 4 4 0 MarR family HTH_11 PF08279.12 AJW69902.1 - 0.013 15.5 0.7 0.17 11.8 0.0 2.5 3 0 0 3 3 3 0 HTH domain HTH_AsnC-type PF13404.6 AJW69902.1 - 0.013 15.3 0.1 0.12 12.2 0.1 2.4 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain DUF1143 PF06608.11 AJW69902.1 - 0.037 14.1 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) HTH_34 PF13601.6 AJW69902.1 - 0.04 14.1 0.0 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_23 PF13384.6 AJW69902.1 - 0.064 13.1 0.1 0.8 9.6 0.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain TssN PF17555.2 AJW69903.1 - 0.0012 18.3 8.4 0.0013 18.2 8.4 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssN YiaAB PF05360.14 AJW69903.1 - 0.0019 18.4 0.3 0.0019 18.4 0.3 2.7 3 0 0 3 3 3 1 yiaA/B two helix domain DUF3742 PF12553.8 AJW69903.1 - 0.042 14.0 0.2 0.061 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF2663 PF10864.8 AJW69903.1 - 0.9 10.0 2.8 19 5.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2663) Copper-bind PF00127.20 AJW69904.1 - 4.3e-06 27.1 0.0 9.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW69904.1 - 0.025 14.7 0.0 0.16 12.1 0.0 2.4 1 1 0 1 1 1 0 Cupredoxin-like domain PsbP PF01789.16 AJW69905.1 - 0.0015 18.6 0.4 0.02 15.1 0.1 2.1 1 1 0 2 2 2 1 PsbP DcrB PF08786.11 AJW69905.1 - 0.092 12.8 0.1 0.31 11.1 0.1 2.0 1 1 0 1 1 1 0 DcrB DUF2271 PF10029.9 AJW69906.1 - 0.15 11.7 0.6 2.2 7.9 0.0 2.9 3 1 1 4 4 4 0 Predicted periplasmic protein (DUF2271) PHINT_rpt PF14882.6 AJW69907.1 - 1.9e-13 50.5 7.7 0.00076 19.7 0.2 3.4 3 0 0 3 3 3 3 Phage-integrase repeat unit DUF3757 PF12582.8 AJW69907.1 - 0.00011 22.5 0.7 0.063 13.7 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3757) Inhibitor_I29 PF08246.12 AJW69907.1 - 0.0099 16.3 4.7 1.9 9.0 0.1 3.3 3 0 0 3 3 3 2 Cathepsin propeptide inhibitor domain (I29) DUF2717 PF10911.8 AJW69907.1 - 0.018 14.7 0.1 13 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2717) Cu-oxidase_3 PF07732.15 AJW69908.1 - 2.1e-08 34.2 0.4 2.5e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AJW69908.1 - 0.058 13.1 1.7 9.6 5.9 0.0 2.9 2 1 1 3 3 3 0 Multicopper oxidase SpoIIM PF01944.17 AJW69909.1 - 2.8e-06 27.5 15.2 2.9e-06 27.4 14.5 1.4 1 1 0 1 1 1 1 Stage II sporulation protein M Thioredoxin_4 PF13462.6 AJW69910.1 - 2.4e-40 138.4 0.0 4e-40 137.7 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 AJW69910.1 - 6.7e-22 78.2 0.1 1.4e-12 47.8 0.0 2.3 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJW69910.1 - 3.2e-11 43.6 0.0 9.5e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJW69910.1 - 0.0077 15.9 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HTH_AsnC-type PF13404.6 AJW69911.1 - 1e-14 54.1 0.2 1.4e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJW69911.1 - 3.4e-12 45.7 0.3 5.3e-12 45.1 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Arc_trans_TRASH PF08394.10 AJW69911.1 - 4.6e-08 33.3 5.9 8.8e-08 32.4 5.9 1.5 1 0 0 1 1 1 1 Archaeal TRASH domain HTH_Tnp_ISL3 PF13542.6 AJW69911.1 - 8.9e-05 21.8 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 AJW69911.1 - 0.00045 19.8 0.0 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AJW69911.1 - 0.00048 19.8 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.19 AJW69911.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AJW69911.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 AJW69911.1 - 0.002 18.2 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AJW69911.1 - 0.0031 17.3 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AJW69911.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.5 2 0 0 2 2 1 1 MarR family GerE PF00196.19 AJW69911.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF2250 PF10007.9 AJW69911.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_38 PF13936.6 AJW69911.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AJW69911.1 - 0.031 14.5 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain LexA_DNA_bind PF01726.16 AJW69911.1 - 0.045 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Rrf2 PF02082.20 AJW69911.1 - 0.13 12.6 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Trypsin_2 PF13365.6 AJW69912.1 - 1.1e-33 117.3 0.1 1.7e-33 116.6 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AJW69912.1 - 1.5e-13 50.9 0.2 3.6e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 AJW69912.1 - 3.7e-12 46.5 0.2 9.1e-12 45.3 0.2 1.6 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 AJW69912.1 - 4.8e-05 23.1 0.2 0.039 13.8 0.2 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AJW69912.1 - 0.01 16.2 1.0 18 5.8 0.2 3.5 3 0 0 3 3 3 0 PDZ domain Peptidase_S32 PF05579.13 AJW69912.1 - 0.01 15.0 1.3 1.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.15 AJW69912.1 - 0.018 14.8 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 AJW69912.1 - 0.02 13.6 0.4 0.02 13.6 0.4 1.6 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.21 AJW69912.1 - 0.049 13.5 0.5 0.14 12.0 0.5 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 AJW69912.1 - 0.2 11.2 3.9 14 5.1 0.0 3.0 2 1 0 2 2 2 0 Putative peptidase (DUF31) 3D PF06725.11 AJW69913.1 - 1.8e-07 31.2 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 3D domain Thioredoxin_3 PF13192.6 AJW69914.1 - 2.9e-13 49.6 0.1 3.3e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 AJW69914.1 - 6.2e-10 39.2 0.1 8.3e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 AJW69914.1 - 4.9e-05 23.7 0.1 5.5e-05 23.5 0.1 1.2 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 AJW69914.1 - 0.0051 17.2 0.0 0.0068 16.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain KaiB PF07689.12 AJW69914.1 - 0.0094 15.7 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin PF00085.20 AJW69914.1 - 0.012 15.6 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 AJW69914.1 - 0.11 12.9 0.5 13 6.3 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin-like domain YHS PF04945.13 AJW69915.1 - 4e-15 55.7 2.3 4.2e-15 55.6 2.3 1.0 1 0 0 1 1 1 1 YHS domain Arc_trans_TRASH PF08394.10 AJW69915.1 - 8.1e-05 22.9 1.0 0.0001 22.5 1.0 1.1 1 0 0 1 1 1 1 Archaeal TRASH domain zf-FCS PF06467.14 AJW69915.1 - 0.0011 18.9 2.6 0.0015 18.4 2.1 1.5 1 1 1 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-FLZ PF04570.14 AJW69915.1 - 0.0017 17.8 1.4 0.002 17.5 1.4 1.1 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 DsbD PF02683.15 AJW69916.1 - 2.5e-17 63.5 17.4 2.5e-17 63.5 17.4 2.2 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AJW69916.1 - 8.9e-07 29.0 24.2 1.3e-06 28.5 9.6 2.4 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF3185 PF11381.8 AJW69916.1 - 0.31 11.1 17.9 1.1 9.3 2.2 4.7 4 2 1 5 5 5 0 Protein of unknown function (DUF3185) EamA PF00892.20 AJW69916.1 - 3 8.0 27.7 7 6.8 7.7 4.1 4 1 0 4 4 4 0 EamA-like transporter family DUF2157 PF09925.9 AJW69916.1 - 4.3 7.1 16.7 1.4 8.7 0.9 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) Thioredoxin_4 PF13462.6 AJW69917.1 - 1.3e-32 113.3 0.0 1.5e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJW69917.1 - 5.9e-15 55.5 0.0 1.4e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJW69917.1 - 1.2e-08 35.4 0.0 1.8e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJW69917.1 - 0.00061 19.5 0.0 0.00076 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AJW69917.1 - 0.033 14.5 0.0 4 7.8 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin PF00085.20 AJW69917.1 - 0.047 13.7 0.1 0.92 9.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin zf-H2C2_2 PF13465.6 AJW69917.1 - 0.086 13.3 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double domain Copper-bind PF00127.20 AJW69918.1 - 1.1e-06 29.0 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW69918.1 - 0.00042 20.4 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Cupredoxin-like domain zf-C2H2_9 PF16293.5 AJW69920.1 - 0.3 11.0 2.1 6.7 6.6 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Lactonase PF10282.9 AJW69922.1 - 1.1e-12 47.9 0.7 3.4e-06 26.5 0.3 3.5 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AJW69922.1 - 2.3e-08 33.0 0.0 0.00033 19.3 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain DUF4221 PF13970.6 AJW69922.1 - 0.0011 18.6 1.0 5.6 6.4 0.0 3.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4221) SGL PF08450.12 AJW69922.1 - 0.011 15.3 0.4 2.4 7.6 0.1 3.0 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF1513 PF07433.11 AJW69922.1 - 0.073 12.1 0.0 3.5 6.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) FlaG PF03646.15 AJW69922.1 - 0.097 12.9 4.3 12 6.1 0.6 3.6 3 0 0 3 3 3 0 FlaG protein CdiI_2 PF18593.1 AJW69925.1 - 0.09 13.4 3.6 0.11 13.1 2.1 1.9 1 1 1 2 2 2 0 CdiI immunity protein Sensor PF13796.6 AJW69925.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative sensor Cu-oxidase_3 PF07732.15 AJW69926.1 - 4.3e-31 107.4 1.8 1.1e-30 106.1 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AJW69926.1 - 5.3e-27 94.2 7.4 1.6e-22 79.7 0.6 4.4 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 AJW69926.1 - 7.2e-14 52.2 0.1 2.7e-09 37.3 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 AJW69926.1 - 0.0089 16.1 0.0 13 5.9 0.0 3.5 3 0 0 3 3 3 1 Cupredoxin-like domain SoxE PF06525.11 AJW69926.1 - 0.029 13.8 0.1 0.27 10.7 0.0 2.5 2 0 0 2 2 2 0 Sulfocyanin (SoxE) domain DUF1741 PF08427.10 AJW69926.1 - 0.047 13.3 0.2 0.072 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Ferric_reduct PF01794.19 AJW69927.1 - 2.5e-08 34.1 11.1 2.5e-08 34.1 11.1 2.6 2 1 1 3 3 3 2 Ferric reductase like transmembrane component Ost4 PF10215.9 AJW69927.1 - 0.04 13.7 1.1 0.19 11.6 1.1 2.2 1 0 0 1 1 1 0 Oligosaccaryltransferase Spermine_synth PF01564.17 AJW69928.1 - 8.3e-16 57.9 0.0 2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 AJW69928.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Tom6 PF17112.5 AJW69928.1 - 0.0007 19.0 4.5 0.4 10.2 1.0 2.8 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom6, fungal Methyltransf_3 PF01596.17 AJW69928.1 - 0.00095 18.4 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.12 AJW69928.1 - 0.0046 17.7 0.0 0.0083 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW69928.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 AJW69928.1 - 0.014 16.4 0.0 0.03 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 AJW69928.1 - 0.11 11.9 0.0 0.64 9.5 0.0 1.9 2 0 0 2 2 2 0 MraW methylase family PIRT PF15099.6 AJW69928.1 - 0.18 11.4 1.7 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family tRNA_bind_2 PF13725.6 AJW69928.1 - 0.24 11.1 0.7 0.38 10.4 0.7 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain NikR_C PF08753.11 AJW69929.1 - 2e-11 43.9 2.1 3.4e-11 43.1 2.1 1.4 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 AJW69929.1 - 6.7e-07 29.0 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family VapB_antitoxin PF09957.9 AJW69929.1 - 0.004 17.0 0.0 0.0083 16.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB ZnuA PF01297.17 AJW69930.1 - 1.6e-70 237.5 0.7 1.8e-70 237.3 0.7 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic OTCace_N PF02729.21 AJW69930.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ABC_tran PF00005.27 AJW69931.1 - 2.5e-35 122.0 0.0 8.9e-35 120.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AJW69931.1 - 1.4e-11 44.7 3.3 2.7e-05 24.1 0.9 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJW69931.1 - 4.3e-06 26.3 1.3 7.4e-05 22.3 1.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AJW69931.1 - 8.5e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AJW69931.1 - 5.6e-05 23.7 2.5 0.00011 22.8 2.5 1.7 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AJW69931.1 - 0.0068 16.6 0.0 0.28 11.4 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 AJW69931.1 - 0.007 16.1 0.4 6.2 6.5 0.0 2.9 3 1 0 3 3 3 2 IstB-like ATP binding protein AAA_27 PF13514.6 AJW69931.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AJW69931.1 - 0.01 15.8 0.0 0.037 13.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 AJW69931.1 - 0.021 15.0 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AJW69931.1 - 0.03 14.4 0.2 0.042 13.9 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 AJW69931.1 - 0.03 13.5 0.2 0.089 12.0 0.2 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.6 AJW69931.1 - 0.081 11.6 3.4 3.4 6.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AJW69931.1 - 0.083 12.6 4.4 0.046 13.4 1.5 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 AJW69931.1 - 0.098 12.9 0.1 0.22 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC-3 PF00950.17 AJW69932.1 - 4.9e-62 209.7 36.9 6e-62 209.5 36.9 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AJW69932.1 - 5.2e-07 29.0 29.8 5.2e-07 29.0 29.8 1.7 1 1 1 2 2 2 1 FecCD transport family CopD PF05425.13 AJW69933.1 - 4.3e-14 52.8 4.6 2e-13 50.6 1.3 2.6 2 0 0 2 2 2 1 Copper resistance protein D SGL PF08450.12 AJW69933.1 - 6.3e-13 48.9 0.2 0.12 11.9 0.0 5.3 1 1 3 5 5 5 5 SMP-30/Gluconolactonase/LRE-like region CopC PF04234.12 AJW69933.1 - 1.6e-07 32.3 0.1 7.2e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 CopC domain Reg_prop PF07494.11 AJW69933.1 - 0.00081 19.3 12.5 21 5.8 0.0 7.3 9 0 0 9 9 9 2 Two component regulator propeller DUF4149 PF13664.6 AJW69933.1 - 4.3 7.7 9.8 0.16 12.3 1.7 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) PPC PF04151.15 AJW69933.1 - 5.4 8.2 6.5 4.7 8.4 0.8 3.2 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Cupredoxin_1 PF13473.6 AJW69935.1 - 0.002 18.2 0.0 0.0078 16.3 0.0 2.0 2 0 0 2 2 2 1 Cupredoxin-like domain Sharpin_PH PF16764.5 AJW69935.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Sharpin PH domain DUF3561 PF12084.8 AJW69940.1 - 0.054 13.5 6.0 0.06 13.4 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) Bac_export_2 PF01312.19 AJW69940.1 - 0.37 10.0 2.6 4 6.6 0.5 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family HTH_24 PF13412.6 AJW69941.1 - 3.9e-17 61.5 0.1 8e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AJW69941.1 - 5.9e-13 48.5 0.1 1.3e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AJW69941.1 - 4.8e-09 36.0 0.0 6.6e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 AJW69941.1 - 6.4e-08 32.4 0.3 0.00041 20.2 0.3 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AJW69941.1 - 1.1e-07 31.7 0.0 0.00066 19.5 0.0 2.4 2 0 0 2 2 2 2 MarR family HTH_IclR PF09339.10 AJW69941.1 - 4.6e-06 26.3 0.0 0.035 13.9 0.0 2.2 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_20 PF12840.7 AJW69941.1 - 2.3e-05 24.4 0.0 0.03 14.4 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain Rrf2 PF02082.20 AJW69941.1 - 3.4e-05 24.1 0.2 0.0043 17.4 0.1 2.3 2 0 0 2 2 2 1 Transcriptional regulator HTH_34 PF13601.6 AJW69941.1 - 3.9e-05 23.7 0.0 0.085 13.0 0.0 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain HTH_45 PF14947.6 AJW69941.1 - 0.00019 21.4 0.1 0.64 10.1 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn-helix HTH_40 PF14493.6 AJW69941.1 - 0.0013 19.1 0.0 0.19 12.2 0.0 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AJW69941.1 - 0.0073 16.3 0.1 4 7.5 0.0 2.6 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 AJW69941.1 - 0.012 15.8 0.2 0.1 12.8 0.1 2.2 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain LexA_DNA_bind PF01726.16 AJW69941.1 - 0.018 14.8 0.1 0.58 10.0 0.0 2.5 2 0 0 2 2 2 0 LexA DNA binding domain DprA_WH PF17782.1 AJW69941.1 - 0.057 13.5 0.0 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 DprA winged helix domain RP-C PF03428.13 AJW69941.1 - 0.091 12.4 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Replication protein C N-terminal domain HTH_29 PF13551.6 AJW69941.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix RMMBL PF07521.12 AJW69942.1 - 0.17 11.9 0.1 4.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Zn-dependent metallo-hydrolase RNA specificity domain CtsR_C PF17727.1 AJW69942.1 - 0.27 11.4 0.4 6.7 6.9 0.2 2.3 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain CHRD PF07452.12 AJW69943.1 - 2.5e-05 25.2 0.0 3.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 CHRD domain Rhomboid PF01694.22 AJW69944.1 - 1.8e-33 115.7 17.4 1.8e-33 115.7 17.4 1.4 2 0 0 2 2 2 1 Rhomboid family Tautomerase PF01361.21 AJW69945.1 - 2.2e-15 56.3 0.0 2.4e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 AJW69945.1 - 8.6e-07 29.0 0.0 8.9e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.6 AJW69945.1 - 0.028 14.7 0.0 0.029 14.6 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme CN_hydrolase PF00795.22 AJW69946.1 - 8.9e-56 189.1 0.0 1e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-C4_Topoisom PF01396.19 AJW69947.1 - 9.2e-07 28.5 8.2 3.3e-06 26.8 1.0 2.7 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 AJW69947.1 - 0.91 10.1 5.8 2 9.0 0.6 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ogr_Delta PF04606.12 AJW69947.1 - 1.1 9.2 15.5 1.4 8.9 1.5 3.6 3 2 0 3 3 3 0 Ogr/Delta-like zinc finger Thiolase_N PF00108.23 AJW69948.1 - 3e-22 79.2 0.1 1.5e-21 76.9 0.1 2.1 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AJW69948.1 - 2.6e-12 46.5 0.5 8.3e-10 38.4 0.0 3.4 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AJW69948.1 - 0.00083 19.0 0.1 0.05 13.2 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AJW69948.1 - 0.053 13.5 2.2 2.9 7.9 0.1 3.5 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain OB_aCoA_assoc PF01796.17 AJW69949.1 - 5.5e-10 39.1 0.1 7.8e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 AJW69949.1 - 7.2e-06 25.8 0.3 1e-05 25.3 0.3 1.2 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 AJW69949.1 - 0.00021 20.9 2.6 0.00037 20.1 2.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain TackOD1 PF18551.1 AJW69949.1 - 0.0049 16.6 0.2 0.0061 16.2 0.2 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 PHF5 PF03660.14 AJW69949.1 - 0.0089 16.2 0.4 0.013 15.7 0.4 1.3 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.7 AJW69949.1 - 0.026 14.5 0.3 0.04 13.9 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.18 AJW69949.1 - 0.31 10.9 2.1 9.6 6.2 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DZR PF12773.7 AJW69950.1 - 8.7e-05 22.5 0.5 0.00011 22.1 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AJW69950.1 - 0.00043 19.6 3.6 0.075 12.5 0.4 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AJW69950.1 - 0.00094 18.8 4.4 0.13 12.1 0.3 2.2 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJW69950.1 - 0.0015 18.0 0.9 0.31 10.6 0.1 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zf_UBZ PF18439.1 AJW69950.1 - 0.0018 17.8 1.0 0.95 9.1 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 AJW69950.1 - 0.0019 18.4 0.6 0.55 10.5 0.1 2.2 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain Chordopox_RPO7 PF05864.12 AJW69950.1 - 0.0058 16.9 0.5 0.059 13.6 0.4 2.1 1 1 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Zn-ribbon_8 PF09723.10 AJW69950.1 - 0.0063 16.6 1.7 0.017 15.2 1.7 1.7 1 1 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 AJW69950.1 - 0.0063 16.5 0.4 0.0071 16.4 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 AJW69950.1 - 0.0067 15.7 1.0 0.03 13.6 0.2 2.0 2 0 0 2 2 2 1 Transcription factor zinc-finger FANCL_C PF11793.8 AJW69950.1 - 0.0076 16.4 1.1 0.033 14.3 1.1 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain DUF4428 PF14471.6 AJW69950.1 - 0.0084 16.0 4.1 0.95 9.4 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) zf-Di19 PF05605.12 AJW69950.1 - 0.01 16.1 0.1 0.022 15.0 0.1 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C4_Topoisom PF01396.19 AJW69950.1 - 0.01 15.6 3.4 0.25 11.2 0.3 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-ACC PF17848.1 AJW69950.1 - 0.011 15.7 2.5 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_4 PF13717.6 AJW69950.1 - 0.013 15.4 2.0 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 AJW69950.1 - 0.014 15.4 4.4 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein LIM PF00412.22 AJW69950.1 - 0.018 15.3 0.1 0.029 14.6 0.1 1.4 1 1 0 1 1 1 0 LIM domain zf-DNA_Pol PF08996.10 AJW69950.1 - 0.026 14.3 0.8 0.026 14.3 0.8 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DiS_P_DiS PF06750.13 AJW69950.1 - 0.027 14.6 0.7 0.091 12.9 0.7 1.7 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-ISL3 PF14690.6 AJW69950.1 - 0.028 15.1 0.4 4.6 8.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc-ribbons_6 PF07191.12 AJW69950.1 - 0.034 14.1 1.2 0.42 10.6 1.2 2.0 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_15 PF17032.5 AJW69950.1 - 0.038 14.7 0.9 0.047 14.4 0.9 1.1 1 0 0 1 1 1 0 zinc-ribbon family Prok-RING_1 PF14446.6 AJW69950.1 - 0.045 13.7 0.8 0.94 9.5 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Sgf11 PF08209.11 AJW69950.1 - 0.052 13.1 0.8 2.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_3 PF13920.6 AJW69950.1 - 0.063 13.2 1.5 0.32 10.9 1.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 AJW69950.1 - 0.07 13.6 2.0 4.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-IS66 PF13005.7 AJW69950.1 - 0.075 13.5 0.7 2.9 8.4 0.1 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-C2HC5 PF06221.13 AJW69950.1 - 0.075 13.0 2.9 0.22 11.6 2.9 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type PknG_rubred PF16919.5 AJW69950.1 - 0.078 13.1 0.2 0.097 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain DUF983 PF06170.12 AJW69950.1 - 0.086 13.3 0.2 4.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Rad50_zn_hook PF04423.14 AJW69950.1 - 0.098 12.5 0.5 0.098 12.5 0.5 1.7 1 1 1 2 2 2 0 Rad50 zinc hook motif Zn_Tnp_IS1595 PF12760.7 AJW69950.1 - 0.11 12.5 1.3 0.71 9.9 0.0 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 AJW69950.1 - 0.11 12.3 2.3 6.5 6.7 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Fer2_BFD PF04324.15 AJW69950.1 - 0.15 12.4 3.5 2.5 8.5 0.1 2.2 1 1 1 2 2 2 0 BFD-like [2Fe-2S] binding domain Nudix_N_2 PF14803.6 AJW69950.1 - 0.16 11.9 1.9 3.3 7.7 0.2 2.1 2 0 0 2 2 2 0 Nudix N-terminal CpXC PF14353.6 AJW69950.1 - 0.18 11.8 2.6 5.2 7.2 0.2 2.1 1 1 1 2 2 2 0 CpXC protein OrfB_Zn_ribbon PF07282.11 AJW69950.1 - 0.28 11.1 3.5 2 8.4 0.2 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 AJW69950.1 - 0.29 11.1 2.1 4.7 7.2 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-NADH-PPase PF09297.11 AJW69950.1 - 0.31 10.8 4.3 5 6.9 0.3 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf_C2H2_10 PF18414.1 AJW69950.1 - 0.31 10.6 1.7 6.8 6.3 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger ADK_lid PF05191.14 AJW69950.1 - 0.39 10.7 5.6 1.8 8.6 5.5 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid T4_baseplate PF12322.8 AJW69950.1 - 0.42 10.0 2.8 3.2 7.2 0.2 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Rubredoxin_2 PF18073.1 AJW69950.1 - 0.91 9.3 5.7 0.85 9.4 1.1 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain NRDD PF13597.6 AJW69951.1 - 3.4e-26 92.2 0.0 1.5e-18 67.0 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.7 AJW69951.1 - 5.3e-10 39.2 0.0 1.3e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.16 AJW69951.1 - 4.9e-06 27.0 0.0 4.9e-06 27.0 0.0 3.1 3 1 0 3 3 3 1 ATP cone domain TackOD1 PF18551.1 AJW69951.1 - 0.009 15.7 0.8 0.022 14.4 0.1 1.9 2 0 0 2 2 2 1 Thaumarchaeal output domain 1 Lig_C PF18330.1 AJW69951.1 - 0.022 14.8 0.8 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region Ribonuc_red_lgC PF02867.15 AJW69952.1 - 2.5e-181 603.8 0.0 4e-181 603.1 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AJW69952.1 - 9.9e-32 108.8 0.0 2.4e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 AJW69952.1 - 1.6e-21 76.7 0.5 4.6e-21 75.2 0.5 1.9 1 0 0 1 1 1 1 ATP cone domain Glyco_hydro_35 PF01301.19 AJW69953.1 - 0.00048 19.9 0.1 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 AJW69953.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.20 AJW69953.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 EMG1 PF03587.14 AJW69954.1 - 4.3e-40 137.5 0.2 4.8e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF3258 PF11646.8 AJW69954.1 - 0.0067 16.5 1.3 0.013 15.6 1.1 1.6 1 1 1 2 2 2 1 Protein of unknown function DUF3258 Rpr2 PF04032.16 AJW69955.1 - 6.1e-14 52.1 0.9 7.5e-14 51.8 0.9 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_1 PF00130.22 AJW69955.1 - 0.081 12.8 1.0 0.14 12.0 1.0 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.15 AJW69955.1 - 0.093 12.8 2.5 0.42 10.7 2.5 1.9 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger PapD-like PF14874.6 AJW69955.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 1 0 1 1 1 0 Flagellar-associated PapD-like AAA_assoc PF14363.6 AJW69955.1 - 0.15 12.4 0.1 0.38 11.1 0.1 1.5 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA HATPase_c PF02518.26 AJW69956.1 - 6.7e-19 68.5 0.6 1.5e-18 67.4 0.6 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AJW69956.1 - 1.2e-15 57.7 0.1 5.3e-15 55.6 0.1 2.1 1 0 0 1 1 1 1 PAS domain HAMP PF00672.25 AJW69956.1 - 1.9e-12 47.3 0.0 1.4e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AJW69956.1 - 9.8e-11 41.5 0.6 9.8e-11 41.5 0.6 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW69956.1 - 3.8e-10 39.6 0.5 3.8e-10 39.6 0.5 2.2 2 0 0 2 2 2 1 GHKL domain PAS PF00989.25 AJW69956.1 - 3.3e-09 36.7 0.0 7.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AJW69956.1 - 8.3e-08 32.4 0.0 2.2e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AJW69956.1 - 0.00028 20.7 0.2 0.00091 19.1 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW69956.1 - 0.00039 20.4 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_4 PF08448.10 AJW69956.1 - 0.0038 17.5 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold DUF948 PF06103.11 AJW69956.1 - 0.012 15.9 0.5 4.7 7.5 0.0 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PAS_8 PF13188.7 AJW69956.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain LAGLIDADG_1 PF00961.19 AJW69956.1 - 0.18 12.8 0.2 0.18 12.8 0.2 3.8 4 0 0 4 4 4 0 LAGLIDADG endonuclease 4HB_MCP_1 PF12729.7 AJW69956.1 - 5.5 6.5 22.8 0.073 12.6 8.2 4.2 3 2 0 3 3 3 0 Four helix bundle sensory module for signal transduction Response_reg PF00072.24 AJW69957.1 - 6.5e-19 68.1 0.2 7.2e-19 68.0 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Ribosomal_S19e PF01090.19 AJW69958.1 - 1.4e-49 167.4 0.0 1.5e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e dsDNA_bind PF01984.20 AJW69959.1 - 1.1e-23 83.6 0.7 1.2e-23 83.5 0.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ADH_zinc_N PF00107.26 AJW69960.1 - 7.7e-26 90.6 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AJW69960.1 - 1.4e-20 73.2 0.1 2.2e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AJW69960.1 - 2.6e-18 67.3 0.1 5.2e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AJW69960.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HpcH_HpaI PF03328.14 AJW69961.1 - 1.5e-47 161.5 0.0 1.8e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AJW69961.1 - 1.8e-17 63.5 0.1 2.4e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 AJW69961.1 - 0.0062 15.5 0.4 0.0079 15.1 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Ribosomal_S19e PF01090.19 AJW69961.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S19e Response_reg PF00072.24 AJW69962.1 - 6.6e-21 74.6 0.3 7.3e-21 74.4 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TrkA_N PF02254.18 AJW69962.1 - 0.0024 18.1 1.1 0.093 13.0 1.1 3.0 1 1 0 1 1 1 1 TrkA-N domain NKWYS PF10364.9 AJW69962.1 - 0.056 13.6 0.1 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative capsular polysaccharide synthesis protein 3HCDH_RFF PF18321.1 AJW69962.1 - 0.11 13.0 0.0 0.53 10.8 0.0 2.0 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF3173 PF11372.8 AJW69962.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) B12-binding PF02310.19 AJW69962.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain TPR_1 PF00515.28 AJW69964.1 - 2.7e-25 87.1 11.9 8e-08 31.8 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJW69964.1 - 4e-19 67.1 3.8 5.2e-06 26.2 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 AJW69964.1 - 2.9e-14 53.1 1.4 1.5e-05 25.2 0.0 3.7 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJW69964.1 - 1.1e-13 50.7 0.0 0.037 14.9 0.0 5.2 1 1 5 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJW69964.1 - 1.4e-13 49.9 10.6 0.0026 17.8 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 AJW69964.1 - 1e-11 43.9 3.1 0.014 15.4 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 AJW69964.1 - 2.4e-11 43.2 9.7 7.2e-06 26.0 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 AJW69964.1 - 3.3e-11 43.2 0.0 7.7e-07 29.2 0.0 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJW69964.1 - 4.9e-11 43.0 2.3 3.2e-05 24.4 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 AJW69964.1 - 3.4e-10 39.5 2.5 0.083 12.8 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AJW69964.1 - 6.3e-08 33.1 0.0 2.9e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AJW69964.1 - 9.1e-08 31.7 5.1 0.002 17.7 0.0 4.5 2 1 2 4 4 4 2 TPR repeat ANAPC3 PF12895.7 AJW69964.1 - 2.3e-06 27.7 7.1 0.0028 17.8 1.6 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AJW69964.1 - 2.9e-06 27.6 2.2 2 9.2 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJW69964.1 - 7.5e-06 25.9 9.5 1.1 9.4 0.2 5.1 2 2 2 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 AJW69964.1 - 1.8e-05 23.9 1.9 2.5e-05 23.4 0.2 1.8 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 DUF4919 PF16266.5 AJW69964.1 - 3.3e-05 23.9 3.3 0.26 11.2 0.1 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4919) TPR_15 PF13429.6 AJW69964.1 - 0.00091 18.5 0.2 0.0019 17.4 0.2 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 AJW69964.1 - 0.0011 18.9 6.1 1.2 9.2 4.5 2.8 1 1 0 2 2 2 2 Putative TPR-like repeat MIT PF04212.18 AJW69964.1 - 0.0031 17.5 10.3 0.05 13.7 0.0 4.3 3 1 2 5 5 4 1 MIT (microtubule interacting and transport) domain PPTA PF01239.22 AJW69964.1 - 0.0086 15.8 1.7 0.42 10.4 0.1 3.2 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat Alkyl_sulf_dimr PF14863.6 AJW69964.1 - 0.0088 16.5 0.5 1.1 9.7 0.0 2.8 1 1 2 3 3 3 1 Alkyl sulfatase dimerisation TPR_20 PF14561.6 AJW69964.1 - 0.011 16.0 0.3 6.2 7.2 0.2 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 AJW69964.1 - 0.015 14.7 4.4 0.35 10.2 0.1 2.2 1 1 1 2 2 2 0 Coatomer epsilon subunit DUF3856 PF12968.7 AJW69964.1 - 0.016 15.3 0.0 0.93 9.6 0.0 3.3 1 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) SPOB_a PF14689.6 AJW69964.1 - 0.018 14.7 3.6 3.2 7.5 0.1 3.8 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain CHASE7 PF17151.4 AJW69964.1 - 0.022 14.4 0.4 0.08 12.5 0.1 1.8 2 0 0 2 2 2 0 Periplasmic sensor domain Tsi6 PF18660.1 AJW69964.1 - 0.032 14.3 0.8 1.7 8.8 0.4 2.4 1 1 1 2 2 2 0 Tsi6 Daxx PF03344.15 AJW69964.1 - 0.063 13.4 0.7 1.8 8.7 0.1 2.7 1 1 1 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain Type_III_YscG PF09477.10 AJW69964.1 - 0.14 12.3 1.8 4.5 7.4 0.1 2.9 1 1 2 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Lum_binding PF00677.17 AJW69965.1 - 3.3e-44 148.8 8.0 3.1e-24 84.8 0.3 2.0 2 0 0 2 2 2 2 Lumazine binding domain DHBP_synthase PF00926.19 AJW69966.1 - 6.1e-61 205.3 0.0 7e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PAF-AH_p_II PF03403.13 AJW69966.1 - 0.091 11.3 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PEP-utilizers PF00391.23 AJW69966.1 - 0.15 11.8 0.1 14 5.5 0.0 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain DMRL_synthase PF00885.19 AJW69967.1 - 1.1e-31 109.5 0.7 1.2e-31 109.4 0.7 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Metallophos_3 PF14582.6 AJW69967.1 - 0.085 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily GCH_III PF05165.12 AJW69968.1 - 5.8e-48 163.3 0.0 7.4e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase III mCpol PF18182.1 AJW69968.1 - 6.7e-06 26.4 0.7 0.0091 16.3 0.1 2.2 2 0 0 2 2 2 2 minimal CRISPR polymerase domain Guanylate_cyc PF00211.20 AJW69968.1 - 0.00014 21.6 0.1 0.00026 20.7 0.1 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain F420H2_quin_red PF04075.14 AJW69968.1 - 0.0097 16.0 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 1 F420H(2)-dependent quinone reductase NOG1 PF06858.14 AJW69968.1 - 0.036 13.9 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Amidohydro_1 PF01979.20 AJW69969.1 - 1.2e-38 133.4 0.8 1.4e-38 133.1 0.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJW69969.1 - 1.8e-14 54.1 0.2 3.3e-09 36.8 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Orthopox_B11R PF07033.11 AJW69969.1 - 0.79 9.6 3.8 6.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Orthopoxvirus B11R protein RibD_C PF01872.17 AJW69970.1 - 5.6e-50 170.0 0.1 6.2e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 RibD C-terminal domain SWIB PF02201.18 AJW69971.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 SWIB/MDM2 domain Pox_Ag35 PF03286.14 AJW69971.1 - 0.11 12.2 6.3 0.11 12.2 6.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hemerythrin PF01814.23 AJW69972.1 - 1.8e-11 44.8 0.3 2e-10 41.4 0.0 2.4 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain Prominin PF05478.11 AJW69972.1 - 0.00056 18.0 0.1 0.00081 17.5 0.1 1.2 1 0 0 1 1 1 1 Prominin 4HB_MCP_1 PF12729.7 AJW69972.1 - 0.013 15.1 1.5 0.026 14.1 1.5 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction IZUMO PF15005.6 AJW69972.1 - 0.034 14.7 1.6 0.055 14.0 0.5 1.9 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Spore_YtfJ PF09579.10 AJW69972.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) UPF0113_N PF17833.1 AJW69972.1 - 0.093 13.3 0.1 0.32 11.6 0.1 2.0 1 1 0 1 1 1 0 UPF0113 Pre-PUA domain Aldedh PF00171.22 AJW69974.1 - 9.8e-145 482.6 0.1 1.1e-144 482.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNAD3 PF18749.1 AJW69974.1 - 0.0073 15.5 0.3 0.016 14.4 0.3 1.5 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 3 RRF PF01765.19 AJW69974.1 - 0.099 12.6 0.4 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Dynactin_p22 PF07426.11 AJW69975.1 - 0.0054 16.6 0.2 0.0068 16.3 0.2 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 EIF_2_alpha PF07541.12 AJW69975.1 - 0.013 15.6 1.3 0.039 14.0 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit BORCS6 PF10157.9 AJW69975.1 - 0.068 13.4 0.0 0.089 13.0 0.0 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 TFIIE_alpha PF02002.17 AJW69976.1 - 1.1e-15 57.3 1.3 1.1e-15 57.3 1.3 1.5 2 0 0 2 2 2 1 TFIIE alpha subunit Sushi_2 PF09014.10 AJW69976.1 - 0.032 14.1 1.1 0.052 13.4 1.1 1.3 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain zf-RRN7 PF11781.8 AJW69976.1 - 0.04 13.6 0.4 0.061 13.0 0.4 1.3 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Sigma70_r3 PF04539.16 AJW69976.1 - 0.07 13.2 0.7 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 TrmB PF01978.19 AJW69976.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB zf-ACC PF17848.1 AJW69976.1 - 0.091 12.9 0.2 0.25 11.4 0.2 1.8 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain IBR PF01485.21 AJW69976.1 - 0.092 13.0 0.9 0.15 12.3 0.9 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 AJW69976.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf_CopZ PF18423.1 AJW69976.1 - 0.25 11.3 0.3 0.25 11.3 0.3 2.3 1 1 1 2 2 2 0 Zinc binding domain Zn_ribbon_recom PF13408.6 AJW69976.1 - 0.4 11.2 0.1 0.4 11.2 0.1 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Trm56 PF01994.16 AJW69977.1 - 4.7e-50 168.5 0.2 6.8e-50 168.0 0.2 1.2 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SpoU_methylase PF00588.19 AJW69977.1 - 6.2e-06 26.4 0.0 9.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.6 AJW69977.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP CsgE PF10627.9 AJW69977.1 - 0.0069 16.6 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 Curli assembly protein CsgE GTP-bdg_N PF13167.6 AJW69978.1 - 2.1e-18 66.7 0.0 1e-17 64.6 0.0 2.1 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 AJW69978.1 - 7.7e-18 64.6 0.2 2.4e-17 63.0 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 AJW69978.1 - 1.7e-16 60.5 2.8 4.3e-16 59.3 2.8 1.7 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region FeoB_N PF02421.18 AJW69978.1 - 2.7e-09 36.7 0.8 4.5e-09 36.0 0.8 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AJW69978.1 - 1.7e-07 31.3 6.0 0.0019 18.1 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 AJW69978.1 - 0.00015 21.4 2.3 0.0051 16.4 2.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 AJW69978.1 - 0.00015 21.3 3.0 0.00031 20.2 2.9 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MnmE_helical PF12631.7 AJW69978.1 - 0.0002 21.6 0.2 0.00041 20.6 0.2 1.4 1 0 0 1 1 1 1 MnmE helical domain Ras PF00071.22 AJW69978.1 - 0.00077 19.1 2.1 0.0028 17.3 2.1 1.9 1 1 0 1 1 1 1 Ras family PduV-EutP PF10662.9 AJW69978.1 - 0.01 15.6 6.2 0.054 13.2 4.4 2.7 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 AJW69978.1 - 0.015 15.3 2.3 0.026 14.5 1.3 1.8 2 0 0 2 2 1 0 C-terminal region of MMR_HSR1 domain Trans_reg_C PF00486.28 AJW69978.1 - 0.028 14.5 0.2 3.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal AAA PF00004.29 AJW69978.1 - 0.031 14.7 1.1 8.9 6.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 AJW69978.1 - 0.036 14.3 1.5 0.83 9.9 1.0 2.9 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 AJW69978.1 - 0.043 13.4 3.3 1.4 8.5 0.1 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AJW69978.1 - 0.044 13.6 2.0 0.14 11.9 0.3 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AJW69978.1 - 0.12 12.9 1.6 0.3 11.6 0.6 2.4 2 1 1 3 3 2 0 ABC transporter Dynamin_N PF00350.23 AJW69978.1 - 0.13 12.3 2.7 0.91 9.6 2.7 2.6 1 1 0 1 1 1 0 Dynamin family DUF2408 PF10303.9 AJW69978.1 - 1.6 9.3 6.0 8 7.0 2.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PhoU PF01895.19 AJW69979.1 - 3.2e-24 85.2 14.2 3.5e-17 62.6 1.5 2.4 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 AJW69979.1 - 7.5e-08 32.1 0.1 3.9e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin UBA PF00627.31 AJW69979.1 - 0.066 13.1 0.2 0.84 9.6 0.1 2.7 2 0 0 2 2 2 0 UBA/TS-N domain PUA PF01472.20 AJW69980.1 - 2.1e-09 37.2 0.3 5.1e-09 36.0 0.3 1.7 2 0 0 2 2 2 1 PUA domain TGT_C2 PF14810.6 AJW69980.1 - 2.5e-07 30.7 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase DUF3228 PF11539.8 AJW69980.1 - 0.11 12.0 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) NAC PF01849.18 AJW69981.1 - 7.8e-14 51.4 1.2 1.5e-13 50.5 1.2 1.4 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 AJW69981.1 - 0.012 15.5 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain Copper-bind PF00127.20 AJW69982.1 - 5.5e-05 23.5 0.1 5.5e-05 23.5 0.1 2.9 1 1 2 3 3 3 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW69982.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 Cupredoxin-like domain Bep_C_terminal PF17841.1 AJW69982.1 - 0.57 10.4 6.0 12 6.2 0.5 3.0 2 1 1 3 3 3 0 BID domain of Bartonella effector protein (Bep) Com_YlbF PF06133.11 AJW69982.1 - 0.6 10.7 12.9 0.12 13.0 9.0 1.8 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Rieske_3 PF18465.1 AJW69982.1 - 0.87 9.9 6.4 0.51 10.6 2.1 2.4 1 1 2 3 3 3 0 Rieske 3Fe-4S STI1 PF17830.1 AJW69982.1 - 2.3 8.2 59.9 0.26 11.2 24.2 3.7 1 1 2 3 3 3 0 STI1 domain COG6 PF06419.11 AJW69983.1 - 0.0002 19.7 4.4 0.00024 19.5 4.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 V-ATPase_G PF03179.15 AJW69983.1 - 0.0021 18.5 4.5 0.0026 18.3 4.5 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3723 PF12520.8 AJW69983.1 - 0.0069 15.1 0.2 0.0084 14.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Apolipoprotein PF01442.18 AJW69983.1 - 0.011 15.6 5.1 0.02 14.8 5.1 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CsoSCA PF08936.10 AJW69983.1 - 0.013 14.2 1.1 0.015 13.9 1.1 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Phage_Mu_Gam PF07352.12 AJW69983.1 - 0.017 15.0 6.3 0.058 13.3 0.7 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein V-ATPase_G_2 PF16999.5 AJW69983.1 - 0.033 14.6 7.4 0.44 11.0 7.4 2.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Muted PF14942.6 AJW69983.1 - 0.051 13.9 4.4 0.081 13.3 4.4 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF883 PF05957.13 AJW69983.1 - 0.066 13.8 5.0 1.8 9.2 1.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.13 AJW69983.1 - 0.084 13.0 7.8 0.14 12.2 7.8 1.4 1 1 0 1 1 1 0 DivIVA protein YabA PF06156.13 AJW69983.1 - 0.089 13.4 2.3 0.13 12.9 2.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Prominin PF05478.11 AJW69983.1 - 0.13 10.2 2.6 0.17 9.8 2.6 1.1 1 0 0 1 1 1 0 Prominin Spc24 PF08286.11 AJW69983.1 - 0.27 11.5 6.7 0.91 9.8 6.7 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 AJW69983.1 - 0.34 11.4 5.0 1.2 9.7 5.0 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4972 PF16342.5 AJW69983.1 - 0.36 10.5 5.8 0.69 9.6 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) Pup PF05639.11 AJW69983.1 - 1.1 10.2 6.8 0.73 10.8 1.4 2.4 1 1 1 2 2 2 0 Pup-like protein YtxH PF12732.7 AJW69983.1 - 4.6 7.8 9.8 15 6.2 2.0 2.2 1 1 1 2 2 2 0 YtxH-like protein DUF460 PF04312.13 AJW69984.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) RPA_interact_C PF14768.6 AJW69985.1 - 0.0063 17.1 5.6 0.6 10.7 5.6 2.6 1 1 0 1 1 1 1 Replication protein A interacting C-terminal C1_1 PF00130.22 AJW69985.1 - 0.2 11.6 10.4 0.48 10.3 0.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Jas PF16135.5 AJW69985.1 - 0.38 10.9 8.1 3.9 7.7 2.2 2.4 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling PAC4 PF16093.5 AJW69986.1 - 4.8e-06 26.7 0.0 6.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF4128 PF13554.6 AJW69986.1 - 0.0032 17.5 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage related domain of unknown function Chlam_vir PF05475.11 AJW69986.1 - 0.043 13.6 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Pgp3 C-terminal domain UbiD PF01977.16 AJW69987.1 - 3.3e-91 306.2 0.0 3.8e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PGP_phosphatase PF09419.10 AJW69987.1 - 0.055 13.1 0.5 0.43 10.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase 4HBT PF03061.22 AJW69988.1 - 6.4e-16 58.5 0.1 8.9e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AJW69988.1 - 0.00069 19.2 0.2 0.0011 18.5 0.2 1.3 1 0 0 1 1 1 1 MaoC like domain RlmM_FDX PF18125.1 AJW69988.1 - 0.09 13.3 0.0 0.3 11.6 0.0 1.8 1 1 1 2 2 2 0 RlmM ferredoxin-like domain ERp29 PF07749.12 AJW69989.1 - 0.0053 17.6 2.9 1.5 9.7 0.3 2.3 1 1 1 2 2 2 2 Endoplasmic reticulum protein ERp29, C-terminal domain DDE_Tnp_ISL3 PF01610.17 AJW69989.1 - 0.0073 16.1 8.7 0.15 11.7 0.4 2.1 1 1 1 2 2 2 2 Transposase CDC37_C PF08564.10 AJW69989.1 - 0.012 15.7 2.5 2.5 8.3 0.0 3.0 1 1 2 3 3 3 0 Cdc37 C terminal domain SnoaL PF07366.12 AJW69989.1 - 0.013 15.3 0.3 0.032 14.0 0.3 1.7 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase DUF4446 PF14584.6 AJW69989.1 - 0.015 15.3 4.6 1.6 8.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) HNOB PF07700.15 AJW69989.1 - 0.037 14.0 3.3 0.042 13.8 2.8 1.4 1 1 0 1 1 1 0 Haem-NO-binding Phasin_2 PF09361.10 AJW69989.1 - 0.055 13.7 9.4 1.5 9.2 5.1 2.4 1 1 1 2 2 2 0 Phasin protein YkyA PF10368.9 AJW69989.1 - 0.09 12.4 6.8 0.18 11.5 1.6 2.3 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF3080 PF11279.8 AJW69989.1 - 0.11 11.7 10.9 0.43 9.8 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) DUF5486 PF17588.2 AJW69989.1 - 0.11 12.4 1.1 7.7 6.5 0.0 3.2 2 1 2 4 4 4 0 Family of unknown function (DUF5486) ACP PF06857.11 AJW69989.1 - 0.27 11.5 2.2 9.2 6.6 0.2 3.0 1 1 3 4 4 4 0 Malonate decarboxylase delta subunit (MdcD) OmpH PF03938.14 AJW69989.1 - 0.43 10.9 5.7 1.4 9.2 5.8 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DASH_Dad2 PF08654.10 AJW69989.1 - 0.57 10.6 7.6 0.47 10.9 1.2 2.7 1 1 1 2 2 2 0 DASH complex subunit Dad2 YtxH PF12732.7 AJW69989.1 - 0.69 10.5 2.6 5.2 7.7 2.6 2.3 1 1 0 1 1 1 0 YtxH-like protein Sec10 PF07393.11 AJW69989.1 - 0.78 8.1 8.4 0.89 7.9 8.4 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 ECH_1 PF00378.20 AJW69989.1 - 1.2 8.4 5.4 1.6 8.0 2.0 1.9 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase Spore_III_AB PF09548.10 AJW69989.1 - 3.3 7.8 6.6 11 6.1 6.6 1.8 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4298 PF14131.6 AJW69989.1 - 3.3 7.7 11.9 3.8 7.5 2.8 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4298) MbeD_MobD PF04899.12 AJW69989.1 - 4.7 7.4 12.9 0.11 12.6 4.0 2.6 1 1 1 3 3 3 0 MbeD/MobD like FAA_hydro_N_2 PF18288.1 AJW69989.1 - 5.3 7.5 8.1 1.4 9.4 0.6 3.1 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 NYD-SP28 PF14772.6 AJW69989.1 - 6.2 6.9 12.7 19 5.4 4.9 2.7 1 1 1 2 2 2 0 Sperm tail Gln-synt_C-ter PF18318.1 AJW69989.1 - 7.1 6.5 8.0 8.4 6.3 0.2 2.9 1 1 2 3 3 3 0 Glutamine synthetase C-terminal domain YpmT PF17431.2 AJW69990.1 - 0.0038 17.2 0.5 0.0041 17.1 0.5 1.2 1 0 0 1 1 1 1 Uncharacterized YmpT-like DUF4745 PF15923.5 AJW69991.1 - 0.0073 16.3 3.9 0.0088 16.0 2.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4745) Phasin_2 PF09361.10 AJW69991.1 - 0.0076 16.5 5.4 0.082 13.2 1.0 2.3 1 1 0 2 2 2 2 Phasin protein Pox_A12 PF04651.13 AJW69991.1 - 0.017 15.2 5.0 0.32 11.0 2.6 2.1 1 1 1 2 2 2 0 Poxvirus A12 protein LktC PF06261.11 AJW69991.1 - 0.03 14.2 1.8 0.035 14.0 0.9 1.5 1 1 1 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC TAF6_C PF07571.13 AJW69991.1 - 0.063 13.6 0.0 0.7 10.3 0.0 2.1 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain RNase_J_C PF17770.1 AJW69991.1 - 3.2 8.9 7.8 3.7 8.7 0.7 3.2 1 1 3 4 4 4 0 Ribonuclease J C-terminal domain DUF3892 PF13031.6 AJW69995.1 - 0.0073 16.9 0.4 0.011 16.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3892) T4SS PF07996.11 AJW69996.1 - 0.02 15.3 12.5 0.03 14.7 12.5 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins Exonuc_VII_L PF02601.15 AJW69996.1 - 0.023 14.3 9.5 0.029 14.0 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_CP76 PF06892.11 AJW69996.1 - 0.042 13.4 2.6 0.059 12.9 2.6 1.2 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) WXG100 PF06013.12 AJW69996.1 - 0.044 14.0 5.9 0.053 13.8 1.7 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG V-SNARE_C PF12352.8 AJW69996.1 - 0.058 13.7 1.6 0.058 13.7 1.6 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus PriC PF07445.12 AJW69996.1 - 0.17 11.8 13.8 0.21 11.5 13.0 1.6 1 1 1 2 2 2 0 Primosomal replication protein priC HIGH_NTase1 PF05636.11 AJW69996.1 - 1 8.5 13.4 1.9 7.6 12.5 1.8 1 1 0 1 1 1 0 HIGH Nucleotidyl Transferase 5_nucleotid PF05761.14 AJW69996.1 - 1.1 8.1 9.6 2.3 7.0 9.4 1.6 1 1 0 1 1 1 0 5' nucleotidase family DUF2524 PF10732.9 AJW69996.1 - 1.8 8.9 11.2 2 8.8 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) DELLA PF12041.8 AJW69996.1 - 2.1 8.3 5.0 11 6.0 0.3 2.9 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal PIN_8 PF18476.1 AJW69996.1 - 2.3 8.0 16.0 1.3 8.8 12.1 1.8 1 1 1 2 2 2 0 PIN like domain Prominin PF05478.11 AJW69996.1 - 2.4 6.0 16.9 2.7 5.8 10.5 1.9 1 1 1 2 2 2 0 Prominin CorA PF01544.18 AJW69996.1 - 2.4 7.4 7.6 5.5 6.2 7.6 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ATP-cone PF03477.16 AJW69996.1 - 2.6 8.7 7.1 0.57 10.8 1.4 2.4 2 1 0 2 2 2 0 ATP cone domain BshC PF10079.9 AJW69996.1 - 2.8 6.6 15.4 7.4 5.2 15.4 1.7 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC AAA_9 PF12781.7 AJW69996.1 - 2.8 7.0 20.2 0.31 10.1 8.3 2.3 1 1 1 2 2 2 0 ATP-binding dynein motor region NPV_P10 PF05531.12 AJW69996.1 - 4 8.0 19.9 1.3 9.5 2.0 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1492 PF07374.11 AJW69996.1 - 4 7.7 15.5 1 9.6 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1492) MatP PF06303.12 AJW69996.1 - 7.5 7.2 9.0 1 9.9 0.4 3.0 1 1 2 3 3 3 0 MatP N-terminal domain LMBR1 PF04791.16 AJW69996.1 - 8.5 5.2 12.3 9.7 5.0 12.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF16 PF01519.16 AJW69996.1 - 9.1 6.8 17.6 4.8e+02 1.3 16.6 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 HEPN_Toprim_N PF18871.1 AJW69997.1 - 0.023 14.7 1.8 0.035 14.1 1.4 1.5 1 1 1 2 2 2 0 HEPN/Toprim N-terminal domain 1 CCDC106 PF15794.5 AJW69997.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 UPF0061 PF02696.14 AJW69997.1 - 0.2 10.4 5.2 0.31 9.8 5.2 1.3 1 1 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family ApoLp-III PF07464.11 AJW69997.1 - 0.24 11.5 9.1 0.13 12.4 5.7 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Oxidored-like PF09791.9 AJW69997.1 - 0.34 10.6 1.4 11 5.8 0.6 2.8 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal TPR_11 PF13414.6 AJW69997.1 - 0.37 10.5 4.7 9.1 6.1 0.2 3.2 2 1 1 3 3 3 0 TPR repeat BAR_3 PF16746.5 AJW69997.1 - 0.42 10.3 6.3 1.3 8.7 6.1 1.8 1 1 0 1 1 1 0 BAR domain of APPL family RPAP3_C PF13877.6 AJW69997.1 - 0.68 10.5 4.6 21 5.8 4.3 2.9 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 BAR PF03114.18 AJW69997.1 - 1.3 8.6 10.9 0.53 9.9 4.0 2.5 1 1 1 2 2 2 0 BAR domain CTK3_C PF12350.8 AJW69997.1 - 3.1 8.0 8.7 15 5.8 0.7 2.8 1 1 1 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus DDE_Tnp_ISL3 PF01610.17 AJW69997.1 - 8.2 6.1 10.5 10 5.8 8.6 1.8 1 1 1 2 2 2 0 Transposase Syntaxin_2 PF14523.6 AJW69999.1 - 0.014 15.7 2.6 0.014 15.7 2.6 1.4 1 1 0 1 1 1 0 Syntaxin-like protein PaaX_C PF08223.11 AJW69999.1 - 0.2 12.0 0.6 0.71 10.2 0.1 1.8 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain IZUMO PF15005.6 AJW69999.1 - 0.34 11.4 2.8 0.38 11.3 2.8 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated UbiA PF01040.18 AJW70001.1 - 7.5e-39 133.5 21.1 9.4e-39 133.2 21.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family AsnC_trans_reg PF01037.21 AJW70002.1 - 1.5e-12 47.3 0.1 1.9e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain Semialdhyde_dhC PF02774.18 AJW70004.1 - 4.6e-32 111.6 0.0 7.9e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AJW70004.1 - 5.7e-30 104.2 0.1 1.2e-29 103.2 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 AJW70004.1 - 0.0088 15.7 0.1 0.95 9.0 0.0 2.9 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.20 AJW70004.1 - 0.022 14.9 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 AJW70004.1 - 0.042 14.7 0.0 0.07 14.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Aminotran_1_2 PF00155.21 AJW70005.1 - 9.1e-52 176.4 0.1 1e-51 176.3 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CbiA PF01656.23 AJW70006.1 - 1.2e-19 70.6 0.0 2.3e-19 69.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AJW70006.1 - 3.3e-19 69.5 0.1 8.6e-18 64.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AJW70006.1 - 0.00022 21.1 0.0 0.0063 16.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 AJW70006.1 - 0.0039 16.8 0.5 0.5 10.0 0.1 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_16 PF13191.6 AJW70006.1 - 0.011 16.2 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CBP_BcsQ PF06564.12 AJW70006.1 - 0.012 15.0 0.1 0.058 12.9 0.1 2.0 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NTPase_1 PF03266.15 AJW70006.1 - 0.034 14.0 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 AJW70006.1 - 0.037 13.8 0.1 0.18 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AJW70006.1 - 0.04 13.5 0.2 2 7.9 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2846 PF11008.8 AJW70006.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) AAA_23 PF13476.6 AJW70006.1 - 0.1 13.1 1.2 0.29 11.6 1.2 2.1 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 AJW70006.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein CobD_Cbib PF03186.13 AJW70007.1 - 2.3e-87 292.7 0.1 2.8e-87 292.4 0.1 1.1 1 0 0 1 1 1 1 CobD/Cbib protein Phage_holin_3_6 PF07332.11 AJW70007.1 - 0.27 11.3 2.7 0.84 9.7 0.1 2.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III CobS PF02654.15 AJW70008.1 - 3.4e-41 141.7 18.1 3.9e-41 141.5 18.1 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase RseC_MucC PF04246.12 AJW70008.1 - 7.1 6.6 17.0 0.23 11.4 1.3 3.1 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC NTP_transf_3 PF12804.7 AJW70009.1 - 2.9e-14 53.7 0.0 3.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJW70009.1 - 7.5e-09 35.7 0.0 9.4e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AJW70009.1 - 2.7e-05 24.2 0.2 0.00025 21.1 0.2 2.0 1 1 0 1 1 1 1 Cytidylyltransferase NTP_transferase PF00483.23 AJW70009.1 - 7.4e-05 22.4 0.2 0.00017 21.3 0.2 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase Mic1 PF07035.12 AJW70009.1 - 0.035 13.8 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Ribosomal_L44 PF00935.19 AJW70010.1 - 1.1e-24 86.7 9.5 1.1e-24 86.7 9.5 1.6 1 1 1 2 2 2 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 AJW70010.1 - 0.0099 16.3 6.5 0.22 12.0 1.7 2.5 2 0 0 2 2 2 2 Ribosomal protein L33 Adenine_deam_C PF13382.6 AJW70011.1 - 1.7e-47 161.0 0.1 4.7e-47 159.5 0.0 1.8 2 0 0 2 2 2 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 AJW70011.1 - 2.1e-18 66.7 0.0 2.1e-17 63.5 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJW70011.1 - 3.6e-09 36.6 0.0 0.00024 20.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Cpn60_TCP1 PF00118.24 AJW70012.1 - 9.5e-180 598.4 19.3 1.2e-179 598.1 19.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2024 PF09630.10 AJW70013.1 - 8.9e-35 118.4 2.0 9.8e-35 118.3 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) DUF3788 PF12663.7 AJW70014.1 - 0.00062 19.7 0.1 0.00074 19.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3788) GATase PF00117.28 AJW70015.1 - 2.4e-42 144.9 0.0 3.4e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 AJW70015.1 - 3.9e-34 116.6 0.0 8.7e-34 115.5 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 AJW70015.1 - 4.1e-11 42.5 0.3 6.3e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AJW70015.1 - 9.7e-08 32.0 0.1 3.8e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.14 AJW70015.1 - 0.00031 20.4 0.0 0.0095 15.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 AJW70015.1 - 0.00057 18.8 0.0 0.012 14.4 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AJW70015.1 - 0.0029 17.1 0.0 0.068 12.6 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AJW70015.1 - 0.063 13.0 0.1 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 PP-loop family Asn_synthase PF00733.21 AJW70015.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase BLOC1_2 PF10046.9 AJW70016.1 - 0.055 13.8 0.5 0.055 13.8 0.5 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Imm6 PF14434.6 AJW70016.1 - 0.088 12.8 2.9 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Immunity protein Imm6 MAF_flag10 PF01973.18 AJW70017.1 - 1.6e-37 128.8 0.8 2.4e-37 128.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPK_catalytic PF04263.16 AJW70017.1 - 0.012 15.7 0.1 0.031 14.3 0.0 1.7 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain Pterin_bind PF00809.22 AJW70018.1 - 2.3e-51 174.8 0.0 4.2e-51 174.0 0.0 1.4 1 1 0 1 1 1 1 Pterin binding enzyme IMPDH PF00478.25 AJW70019.1 - 8.9e-148 491.9 7.2 1e-147 491.7 7.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AJW70019.1 - 7.1e-21 74.4 2.0 7.9e-10 39.0 0.1 3.3 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 AJW70019.1 - 2.9e-10 40.0 6.4 1.8e-05 24.3 3.9 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 AJW70019.1 - 3.6e-07 29.9 1.1 0.01 15.3 0.1 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein FMN_dh PF01070.18 AJW70019.1 - 5.7e-07 28.9 8.1 2.8e-06 26.6 8.1 2.2 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 AJW70019.1 - 0.0027 17.0 6.1 0.0051 16.1 1.1 2.5 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.14 AJW70019.1 - 0.0034 16.6 1.6 0.0034 16.6 1.6 2.3 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase PK PF00224.21 AJW70019.1 - 0.0048 15.8 0.1 0.04 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain ThiG PF05690.14 AJW70019.1 - 0.023 14.0 1.7 0.049 12.9 0.6 2.1 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.6 AJW70019.1 - 0.042 13.3 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Radical_SAM PF04055.21 AJW70019.1 - 0.057 13.8 0.0 4.7 7.6 0.0 2.4 1 1 0 1 1 1 0 Radical SAM superfamily G3P_antiterm PF04309.12 AJW70019.1 - 0.17 11.3 3.3 5.2 6.4 0.1 3.1 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator AIM24 PF01987.17 AJW70020.1 - 0.027 14.2 0.1 0.055 13.3 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial biogenesis AIM24 Beta-APP PF03494.13 AJW70020.1 - 0.059 13.2 0.5 0.14 12.0 0.5 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) PDT PF00800.18 AJW70021.1 - 1e-58 198.2 0.1 1.3e-58 197.8 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 AJW70021.1 - 3.6e-07 29.8 0.0 6.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain ECR1_N PF14382.6 AJW70022.1 - 5.1e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Zn_ribbon_SprT PF17283.2 AJW70022.1 - 0.27 11.2 2.7 0.62 10.0 0.9 2.3 2 1 0 2 2 2 0 SprT-like zinc ribbon domain DNA_RNApol_7kD PF03604.13 AJW70022.1 - 2 8.2 7.4 28 4.5 7.4 2.5 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit ADH_N PF08240.12 AJW70023.1 - 3.2e-25 88.1 0.3 5.1e-25 87.5 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJW70023.1 - 1.3e-24 86.7 0.0 2.3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AJW70023.1 - 8.8e-18 65.6 0.0 1.5e-17 64.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Big_3_4 PF13754.6 AJW70023.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function KTI12 PF08433.10 AJW70023.1 - 0.069 12.6 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 6PF2K PF01591.18 AJW70023.1 - 0.18 11.1 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TPR_1 PF00515.28 AJW70024.1 - 3.8e-22 77.1 1.6 9.8e-08 31.5 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJW70024.1 - 3.4e-20 70.5 0.2 0.00013 21.8 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJW70024.1 - 1.2e-13 50.1 4.2 1.3e-06 28.2 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJW70024.1 - 4.5e-12 46.3 0.0 4.1e-05 24.0 0.0 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 AJW70024.1 - 2.5e-11 43.7 0.0 0.043 14.1 0.0 4.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJW70024.1 - 5.3e-10 39.3 0.0 0.2 12.6 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 AJW70024.1 - 1.7e-09 37.7 0.0 0.87 10.4 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AJW70024.1 - 4.8e-09 36.3 6.9 0.00028 21.1 0.3 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AJW70024.1 - 5.6e-08 32.4 0.0 0.012 15.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 AJW70024.1 - 1.8e-07 30.9 1.1 0.14 12.5 0.0 4.7 5 0 0 5 5 4 2 PPR repeat TPR_16 PF13432.6 AJW70024.1 - 2.3e-07 31.4 0.0 0.00093 19.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJW70024.1 - 2.8e-07 30.5 0.7 0.16 12.1 0.1 3.7 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 AJW70024.1 - 4.4e-07 29.5 0.1 0.069 13.2 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 AJW70024.1 - 2.2e-06 27.7 6.6 0.049 14.0 0.6 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 AJW70024.1 - 1.9e-05 24.2 2.0 0.27 11.0 0.0 4.9 4 3 1 5 5 5 1 TPR repeat DUF4919 PF16266.5 AJW70024.1 - 0.00032 20.7 0.3 0.0034 17.4 0.1 2.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4919) Coatomer_E PF04733.14 AJW70024.1 - 0.00049 19.6 0.2 0.86 9.0 0.0 2.1 2 0 0 2 2 2 2 Coatomer epsilon subunit ATP13 PF12921.7 AJW70024.1 - 0.01 15.7 0.7 1.9 8.3 0.1 3.4 1 1 2 3 3 3 0 Mitochondrial ATPase expression TPR_9 PF13371.6 AJW70024.1 - 0.016 15.3 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 AJW70024.1 - 0.03 14.6 0.0 7.4 6.8 0.0 2.4 2 1 0 2 2 2 0 Tetratrico peptide repeat RepB PF07506.11 AJW70024.1 - 0.042 13.9 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein TPR_20 PF14561.6 AJW70024.1 - 0.12 12.7 0.0 0.68 10.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Diphthamide_syn PF01866.17 AJW70025.1 - 4.1e-64 216.9 0.0 4.8e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein GSDH PF07995.11 AJW70026.1 - 2.3e-82 277.0 0.0 3.2e-82 276.5 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 AJW70026.1 - 0.0051 16.9 2.0 24 5.6 0.1 4.8 4 0 0 4 4 4 1 Two component regulator propeller Tudor_2 PF18104.1 AJW70026.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain HMG-CoA_red PF00368.18 AJW70027.1 - 4.3e-103 345.2 7.7 5.2e-103 344.9 7.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase CAMSAP_CH PF11971.8 AJW70027.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain HisG PF01634.18 AJW70028.1 - 5.4e-45 153.2 0.1 7.2e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 AJW70028.1 - 5.4e-15 55.3 0.0 1.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain Histidinol_dh PF00815.20 AJW70029.1 - 3.5e-139 464.3 0.1 4.3e-139 464.0 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Fib_alpha PF08702.10 AJW70029.1 - 0.056 13.6 3.2 0.05 13.8 1.4 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Aminotran_1_2 PF00155.21 AJW70030.1 - 9.7e-43 146.7 0.0 1.1e-42 146.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AJW70030.1 - 3e-06 26.4 0.0 4.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.19 AJW70030.1 - 0.062 12.2 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V HAD_2 PF13419.6 AJW70031.1 - 1.7e-08 34.8 6.3 6.9e-07 29.5 6.3 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AJW70031.1 - 5.6e-08 33.3 0.1 0.00058 20.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 AJW70031.1 - 0.011 15.3 1.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_like PF13242.6 AJW70031.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like GerE PF00196.19 AJW70031.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family IGPD PF00475.18 AJW70032.1 - 7.3e-47 159.3 0.2 9.6e-47 158.9 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase ANF_receptor PF01094.28 AJW70032.1 - 0.0094 15.1 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region Flagellin_IN PF07196.13 AJW70032.1 - 0.0098 16.1 2.3 0.058 13.6 1.7 2.4 2 0 0 2 2 2 1 Flagellin hook IN motif Binary_toxB_3 PF17476.2 AJW70032.1 - 0.088 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 GATase PF00117.28 AJW70033.1 - 2.8e-24 85.9 0.0 3.4e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 AJW70033.1 - 0.00014 21.8 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 AJW70033.1 - 0.0013 18.5 1.1 1.4 8.6 0.5 2.8 2 1 0 2 2 2 2 Peptidase C26 WI12 PF07107.11 AJW70033.1 - 0.0063 16.6 0.0 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 Wound-induced protein WI12 GATase_3 PF07685.14 AJW70033.1 - 0.0072 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain His_biosynth PF00977.21 AJW70034.1 - 3.4e-71 239.3 0.5 3.9e-71 239.2 0.5 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 AJW70034.1 - 0.0018 17.8 0.4 0.15 11.5 0.1 2.1 2 0 0 2 2 2 2 PcrB family IGPS PF00218.21 AJW70034.1 - 0.0028 16.9 0.0 0.085 12.0 0.0 2.1 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Syd PF07348.12 AJW70034.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Syd protein (SUKH-2) Dus PF01207.17 AJW70034.1 - 0.012 14.7 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AJW70035.1 - 1.4e-84 283.1 2.1 1.7e-84 282.9 2.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AJW70035.1 - 2.7e-08 33.3 0.1 0.00025 20.2 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AJW70035.1 - 1.2e-06 28.1 0.8 0.007 15.8 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 AJW70035.1 - 1.7e-05 24.2 0.2 0.024 14.0 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase ThiG PF05690.14 AJW70035.1 - 0.00077 18.8 0.2 0.43 9.8 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 AJW70035.1 - 0.0018 17.5 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 AJW70035.1 - 0.0096 15.3 0.1 0.83 9.0 0.0 2.4 2 1 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator Trp_syntA PF00290.20 AJW70035.1 - 0.012 14.4 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain IMPDH PF00478.25 AJW70035.1 - 0.026 13.6 2.7 0.079 11.9 0.2 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain PcrB PF01884.17 AJW70035.1 - 0.035 13.6 0.2 0.083 12.3 0.1 1.6 2 0 0 2 2 2 0 PcrB family PRA-CH PF01502.18 AJW70036.1 - 3.2e-31 107.0 0.0 3.9e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PALP PF00291.25 AJW70038.1 - 4.9e-66 223.1 0.3 5.7e-66 222.9 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme C1_2 PF03107.16 AJW70038.1 - 0.036 14.4 1.4 0.073 13.4 1.4 1.4 1 0 0 1 1 1 0 C1 domain S4 PF01479.25 AJW70038.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 S4 domain ThiF PF00899.21 AJW70039.1 - 6.7e-64 215.6 0.4 1e-63 215.0 0.4 1.1 1 0 0 1 1 1 1 ThiF family ThiS PF02597.20 AJW70039.1 - 3.2e-09 37.3 0.0 1.1e-08 35.6 0.0 1.9 2 0 0 2 2 2 1 ThiS family Sacchrp_dh_NADP PF03435.18 AJW70039.1 - 6.9e-06 26.4 1.4 1.8e-05 25.0 1.4 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AJW70039.1 - 0.0061 16.6 0.3 0.016 15.3 0.1 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 AJW70039.1 - 0.15 12.5 0.4 0.45 11.0 0.4 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding He_PIG PF05345.12 AJW70041.1 - 0.046 13.9 3.7 4 7.7 0.2 2.8 2 1 0 2 2 2 0 Putative Ig domain Peptidase_S8 PF00082.22 AJW70042.1 - 3.8e-33 115.0 0.0 8.2e-33 113.9 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 AJW70042.1 - 7.9e-06 26.5 2.6 0.00096 19.8 0.0 2.7 2 0 0 2 2 2 2 Fn3-like domain DUF916 PF06030.12 AJW70042.1 - 5.2e-05 23.3 0.2 0.69 10.0 0.0 3.6 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF916) Romo1 PF10247.9 AJW70042.1 - 0.031 14.7 0.9 0.15 12.5 0.3 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 EF-hand_6 PF13405.6 AJW70042.1 - 5.3 7.2 4.9 8.5 6.6 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain Rieske PF00355.26 AJW70043.1 - 7.5e-07 29.0 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 AJW70043.1 - 2.8e-05 23.8 1.0 5.2e-05 22.9 1.0 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AJW70043.1 - 0.0014 17.9 0.1 0.0034 16.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cytochrome_B PF00033.19 AJW70044.1 - 2.6e-29 102.4 10.4 2.6e-29 102.4 10.4 2.8 3 0 0 3 3 3 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 AJW70044.1 - 8.2e-26 91.0 6.2 8.2e-26 91.0 6.2 3.1 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 AJW70044.1 - 3e-08 33.9 2.9 3e-08 33.9 2.9 3.1 4 0 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.6 AJW70044.1 - 0.00021 21.8 3.0 0.00021 21.8 3.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4405) DUF4079 PF13301.6 AJW70044.1 - 0.098 12.8 5.2 6.7 6.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) Copper-bind PF00127.20 AJW70045.1 - 1.1e-05 25.7 0.1 1.6e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Lipase_C PF18067.1 AJW70045.1 - 0.00086 19.8 0.0 0.0012 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipase C-terminal domain Cupredoxin_1 PF13473.6 AJW70045.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Cupredoxin-like domain CbiM PF01891.16 AJW70045.1 - 0.087 12.6 0.6 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region GatD_N PF18195.1 AJW70046.1 - 0.12 11.8 1.2 0.24 10.7 0.9 1.8 2 1 0 2 2 2 0 GatD N-terminal domain HhH-GPD PF00730.25 AJW70047.1 - 4.9e-14 52.7 0.0 8.3e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 AJW70047.1 - 3.8e-11 43.1 0.1 7.7e-08 32.5 0.1 2.7 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain DUF4974 PF16344.5 AJW70047.1 - 0.0041 17.1 6.5 6.2 6.9 0.6 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4974) HHH PF00633.23 AJW70047.1 - 0.0076 16.1 0.0 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Beta-Casp PF10996.8 AJW70048.1 - 3.5e-15 56.2 0.0 6.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 AJW70048.1 - 5e-15 55.2 0.0 1.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AJW70048.1 - 3.9e-11 42.7 0.0 1.2e-10 41.2 0.0 1.8 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AJW70048.1 - 5.3e-11 42.4 0.0 9.9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AJW70048.1 - 4.6e-09 36.6 1.3 4.2e-08 33.4 1.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AJW70048.1 - 4e-06 26.8 0.0 2e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 AJW70048.1 - 0.0009 18.5 0.0 0.0022 17.3 0.0 1.7 1 1 0 1 1 1 1 Putative beta-lactamase-like family DUF2220 PF09983.9 AJW70048.1 - 0.039 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Fer4 PF00037.27 AJW70050.1 - 2e-11 43.2 10.3 7.8e-06 25.5 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJW70050.1 - 4.5e-09 36.7 3.2 6.5e-09 36.2 3.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJW70050.1 - 8.1e-09 35.2 7.3 7.8e-05 22.6 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AJW70050.1 - 1.2e-08 34.9 1.5 1.7e-08 34.4 1.5 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AJW70050.1 - 1.2e-06 28.2 8.3 0.0014 18.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJW70050.1 - 2.7e-06 27.8 4.5 0.0042 17.6 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 AJW70050.1 - 1.2e-05 25.3 8.0 0.00027 21.0 8.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJW70050.1 - 1.5e-05 25.0 4.6 8.9e-05 22.6 4.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJW70050.1 - 8.6e-05 22.7 7.5 0.022 15.2 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AJW70050.1 - 0.00016 22.5 3.4 0.28 12.1 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AJW70050.1 - 0.00092 20.0 2.4 0.43 11.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJW70050.1 - 0.0019 18.9 10.5 0.0072 17.0 2.6 2.3 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_8 PF13183.6 AJW70050.1 - 0.0023 18.3 5.7 0.025 15.0 5.9 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJW70050.1 - 0.0032 18.3 10.4 0.098 13.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AJW70050.1 - 0.028 15.0 7.5 1.2 9.7 7.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJW70050.1 - 0.59 10.4 9.7 1.4 9.2 2.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain TGT PF01702.18 AJW70051.1 - 1.3e-67 228.4 0.0 1.9e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 AJW70051.1 - 5.2e-09 36.1 0.1 9e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) DUF3879 PF12995.7 AJW70051.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) AAA_18 PF13238.6 AJW70052.1 - 5.1e-12 46.5 1.1 8e-12 45.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 AJW70052.1 - 9.4e-07 29.1 0.2 2.1e-05 24.8 0.2 2.4 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 AJW70052.1 - 9.3e-06 26.1 0.5 2.2e-05 24.9 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 AJW70052.1 - 0.00013 22.4 0.2 0.0017 18.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CoaE PF01121.20 AJW70052.1 - 0.00051 19.8 0.8 0.00088 19.0 0.0 1.8 2 0 0 2 2 2 1 Dephospho-CoA kinase NTPase_1 PF03266.15 AJW70052.1 - 0.00082 19.3 3.9 0.0024 17.8 0.1 2.7 2 1 1 3 3 3 1 NTPase AAA_5 PF07728.14 AJW70052.1 - 0.0021 18.0 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 AJW70052.1 - 0.0031 17.3 0.1 0.0087 15.8 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase SKI PF01202.22 AJW70052.1 - 0.0033 17.6 0.1 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase KTI12 PF08433.10 AJW70052.1 - 0.0049 16.4 0.1 0.01 15.3 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_3 PF07726.11 AJW70052.1 - 0.031 14.1 0.1 3 7.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AJW70052.1 - 0.053 13.3 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AJW70052.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 AJW70052.1 - 0.097 12.4 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 AJW70052.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1_C PF08438.10 AJW70053.1 - 1.1e-27 96.8 0.0 3.7e-27 95.1 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AJW70053.1 - 1.5e-20 73.4 0.1 8.5e-19 67.7 0.0 2.8 2 1 1 3 3 3 1 50S ribosome-binding GTPase TGS PF02824.21 AJW70053.1 - 4.9e-10 39.3 0.1 1.7e-09 37.6 0.1 2.0 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJW70053.1 - 5.4e-06 26.0 0.2 2.6e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.13 AJW70053.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Peptidase_M22 PF00814.25 AJW70054.1 - 3.4e-74 249.9 0.0 4e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family GP57 PF17594.2 AJW70055.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 Pkinase PF00069.25 AJW70056.1 - 9.1e-10 38.3 0.8 1.1e-09 38.1 0.8 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 AJW70056.1 - 5.8e-08 32.5 0.2 8.1e-08 32.1 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 AJW70056.1 - 1.1e-07 31.4 0.1 7.3e-07 28.8 0.1 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 AJW70056.1 - 6.4e-06 25.6 0.1 1.5e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AJW70056.1 - 1.2e-05 25.4 0.0 0.0037 17.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 AJW70056.1 - 0.00015 21.5 0.3 0.0002 21.1 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Ham1p_like PF01725.16 AJW70057.1 - 3.6e-42 144.4 0.0 4e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Baculo_LEF5_C PF11792.8 AJW70057.1 - 0.11 12.2 0.2 8.7 6.1 0.1 2.3 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Wyosine_form PF08608.12 AJW70058.1 - 7.1e-20 71.1 0.0 4.7e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.21 AJW70058.1 - 9.2e-19 68.4 0.0 3.4e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Paf67 PF10255.9 AJW70058.1 - 0.0053 15.8 0.1 0.008 15.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 IMP_cyclohyd PF07826.11 AJW70058.1 - 0.057 13.0 0.1 0.096 12.3 0.1 1.6 1 1 0 1 1 1 0 IMP cyclohydrolase-like protein Fer4_14 PF13394.6 AJW70058.1 - 0.14 12.3 1.7 2.8 8.1 0.8 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain TSP_3 PF02412.18 AJW70059.1 - 6.9e-44 147.2 260.1 0.00047 19.8 3.4 28.3 27 8 1 28 28 28 20 Thrombospondin type 3 repeat Laterosporulin PF17861.1 AJW70059.1 - 0.25 11.8 1.5 59 4.2 0.0 4.2 4 0 0 4 4 4 0 Laterosporulin defensin-like peptide TSP_3 PF02412.18 AJW70060.1 - 1e-32 111.5 224.1 0.00035 20.2 1.8 27.2 24 7 6 30 30 30 17 Thrombospondin type 3 repeat MRP-S26 PF14943.6 AJW70060.1 - 0.17 11.8 0.5 9.4 6.1 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 NOPS PF08075.11 AJW70060.1 - 2.2 8.5 18.0 1.5e+02 2.6 0.0 8.6 9 1 0 9 9 9 0 NOPS (NUC059) domain TSP_3 PF02412.18 AJW70061.1 - 7.7e-30 102.3 210.2 0.00024 20.7 2.6 25.6 25 8 4 29 29 29 17 Thrombospondin type 3 repeat MRP-S26 PF14943.6 AJW70061.1 - 0.0052 16.7 4.7 2.8 7.8 0.0 4.2 5 0 0 5 5 5 2 Mitochondrial ribosome subunit S26 Dus PF01207.17 AJW70062.1 - 1.5e-75 254.2 0.0 1.7e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 AJW70062.1 - 3.1e-08 33.2 0.1 4.3e-06 26.1 0.1 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 AJW70062.1 - 0.00025 20.3 0.1 0.0018 17.5 0.0 2.2 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Oxidored_FMN PF00724.20 AJW70062.1 - 0.00042 19.7 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 AJW70062.1 - 0.0014 18.1 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein MR_MLE_C PF13378.6 AJW70062.1 - 0.01 15.4 0.0 0.028 14.0 0.0 1.7 1 1 1 2 2 2 0 Enolase C-terminal domain-like FMN_dh PF01070.18 AJW70062.1 - 0.048 12.7 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NIR_SIR_ferr PF03460.17 AJW70062.1 - 0.049 13.5 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Trp_DMAT PF11991.8 AJW70062.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase B12-binding PF02310.19 AJW70062.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain AsnC_trans_reg PF01037.21 AJW70063.1 - 2.5e-12 46.6 0.0 2.9e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJW70063.1 - 0.0011 18.9 0.1 0.0013 18.7 0.1 1.1 1 0 0 1 1 1 1 NapD protein P-II PF00543.22 AJW70064.1 - 3.2e-11 43.7 2.2 3.7e-11 43.5 2.2 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF5112 PF17139.4 AJW70065.1 - 0.0032 17.0 0.0 0.0037 16.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5112) HTH_10 PF04967.12 AJW70065.1 - 0.0061 16.3 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 HTH DNA binding domain Ovate PF04844.13 AJW70065.1 - 0.017 15.1 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 Transcriptional repressor, ovate Mga PF05043.13 AJW70065.1 - 0.036 14.6 0.0 0.039 14.5 0.0 1.2 1 0 0 1 1 1 0 Mga helix-turn-helix domain I-set PF07679.16 AJW70066.1 - 0.039 14.0 0.1 0.089 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF3244 PF11589.8 AJW70066.1 - 0.38 10.9 4.4 0.12 12.4 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) APC_u15 PF16636.5 AJW70066.1 - 0.72 10.3 3.8 0.73 10.3 0.1 2.4 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 NERD PF08378.11 AJW70067.1 - 0.021 15.3 0.7 0.085 13.3 0.1 2.0 2 0 0 2 2 2 0 Nuclease-related domain TBP PF00352.21 AJW70069.1 - 1.7e-54 181.7 0.0 1.4e-27 95.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJW70069.1 - 3e-06 27.3 0.0 0.044 13.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) PAS_11 PF14598.6 AJW70069.1 - 0.058 13.5 0.0 13 6.0 0.0 2.2 2 0 0 2 2 2 0 PAS domain ASCH PF04266.14 AJW70070.1 - 1.1e-11 45.2 0.0 1.5e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 ASCH domain DUF3850 PF12961.7 AJW70070.1 - 0.0082 16.2 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3850) PALP PF00291.25 AJW70071.1 - 4.2e-22 78.9 0.5 3.2e-19 69.4 0.1 3.2 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme VWA PF00092.28 AJW70073.1 - 2.4e-05 24.6 0.1 6.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 AJW70073.1 - 0.0025 18.4 0.0 0.015 16.0 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_5 PF07728.14 AJW70074.1 - 2.9e-23 82.4 0.1 4.4e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AJW70074.1 - 5.1e-13 49.0 0.0 7.4e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 AJW70074.1 - 2.5e-07 31.2 0.0 5.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AJW70074.1 - 2.4e-06 27.2 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 AJW70074.1 - 9.1e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 AJW70074.1 - 9.9e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 AJW70074.1 - 0.00043 20.7 0.0 0.00091 19.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 AJW70074.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbbQ_C PF08406.10 AJW70074.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Sigma54_activ_2 PF14532.6 AJW70074.1 - 0.0014 18.7 0.0 0.0048 17.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_6 PF12774.7 AJW70074.1 - 0.0015 17.6 0.0 0.0057 15.7 0.0 1.8 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RuvB_N PF05496.12 AJW70074.1 - 0.0016 18.2 0.3 0.082 12.6 0.2 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AJW70074.1 - 0.0017 18.9 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AJW70074.1 - 0.0035 17.6 0.0 0.0077 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 AJW70074.1 - 0.0075 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AJW70074.1 - 0.011 15.4 0.1 0.055 13.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 AJW70074.1 - 0.013 14.9 0.1 0.98 8.8 0.0 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 AJW70074.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 AJW70074.1 - 0.026 13.8 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_35 PF14516.6 AJW70074.1 - 0.027 13.3 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Rad17 PF03215.15 AJW70074.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 AJW70074.1 - 0.041 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 AJW70074.1 - 0.044 13.7 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 AJW70074.1 - 0.048 13.9 0.1 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 AJW70074.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AJW70074.1 - 0.078 12.7 0.4 0.4 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 AJW70074.1 - 0.096 11.9 0.8 1.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 AJW70074.1 - 0.11 13.0 0.1 0.3 11.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 AJW70074.1 - 0.11 11.8 0.1 0.38 10.1 0.0 1.8 3 0 0 3 3 2 0 Bacterial TniB protein AAA_28 PF13521.6 AJW70074.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.24 AJW70075.1 - 7.6e-05 22.0 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 AJW70075.1 - 0.0006 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AJW70075.1 - 0.001 18.7 0.1 0.95 9.0 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AJW70075.1 - 0.0032 16.7 0.3 0.084 12.1 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AJW70075.1 - 0.0038 16.1 0.1 0.0084 15.0 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 AJW70075.1 - 0.012 14.3 0.0 0.42 9.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GDI PF00996.18 AJW70075.1 - 0.048 12.2 0.0 0.1 11.1 0.0 1.5 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.18 AJW70075.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 AJW70075.1 - 0.13 12.9 0.3 2 9.0 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AJW70075.1 - 0.2 10.9 0.2 0.75 9.0 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain RNA_binding PF01877.17 AJW70076.1 - 8.1e-28 97.1 8.6 9.9e-28 96.8 8.6 1.1 1 0 0 1 1 1 1 RNA binding HD_3 PF13023.6 AJW70076.1 - 0.013 15.5 1.7 0.016 15.1 1.6 1.3 1 1 0 1 1 1 0 HD domain Ribosomal_S3Ae PF01015.18 AJW70077.1 - 3.5e-58 196.5 3.2 3.9e-58 196.4 3.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Band_7 PF01145.25 AJW70077.1 - 0.077 13.0 0.2 0.51 10.3 0.2 2.1 1 1 0 1 1 1 0 SPFH domain / Band 7 family tRNA-synt_2b PF00587.25 AJW70078.1 - 9.9e-39 133.1 0.3 2e-38 132.2 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AJW70078.1 - 1.1e-27 96.4 9.6 2.2e-27 95.4 9.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TSP_NTD PF17804.1 AJW70078.1 - 0.67 10.2 7.2 0.13 12.5 3.3 2.0 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Pcc1 PF09341.10 AJW70079.1 - 0.00021 21.3 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DHHA1 PF02272.19 AJW70080.1 - 2.8e-12 47.2 0.0 7.6e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 AJW70080.1 - 0.003 17.8 0.2 0.0059 16.8 0.2 1.4 1 0 0 1 1 1 1 DHH family Ribosomal_S13_N PF08069.12 AJW70081.1 - 7e-27 93.2 0.5 1.2e-26 92.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 AJW70081.1 - 1.3e-11 44.5 0.3 2.2e-11 43.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 FixQ PF05545.11 AJW70084.1 - 0.058 13.4 1.5 0.093 12.7 1.5 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Monooxygenase_B PF04744.12 AJW70087.1 - 5.2e-08 32.1 0.0 1.5e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Monooxygenase subunit B protein AmoC PF04896.12 AJW70088.1 - 2.7e-13 49.8 6.2 3.3e-13 49.5 6.2 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C RTA1 PF04479.13 AJW70088.1 - 0.0042 16.7 0.2 0.0065 16.1 0.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Gram_pos_anchor PF00746.21 AJW70089.1 - 2.4 8.2 4.6 2.2 8.3 0.7 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Archaeal_AmoA PF12942.7 AJW70090.1 - 3e-116 385.6 16.0 3.6e-116 385.3 16.0 1.1 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) MethyltransfD12 PF02086.15 AJW70091.1 - 9.9e-65 218.8 1.1 1.1e-64 218.6 1.1 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF2089 PF09862.9 AJW70091.1 - 0.0014 18.6 0.4 0.0033 17.5 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) DNA_photolyase PF00875.18 AJW70091.1 - 0.013 15.5 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 DNA photolyase Cons_hypoth95 PF03602.15 AJW70091.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Lectin_like PF18560.1 AJW70092.1 - 0.02 15.0 0.1 0.025 14.7 0.1 1.1 1 0 0 1 1 1 0 Lectin like domain LOH1CR12 PF10158.9 AJW70092.1 - 0.041 13.9 0.1 0.45 10.5 0.1 1.9 1 1 1 2 2 2 0 Tumour suppressor protein Response_reg PF00072.24 AJW70093.1 - 4.3e-15 55.8 0.2 5.3e-15 55.6 0.2 1.1 1 0 0 1 1 1 1 Response regulator receiver domain BRCT_3 PF18428.1 AJW70093.1 - 0.041 13.9 0.0 0.087 12.9 0.0 1.7 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain B12-binding_2 PF02607.17 AJW70094.1 - 0.00013 22.4 0.0 0.00031 21.1 0.0 1.6 2 0 0 2 2 2 1 B12 binding domain HTH_23 PF13384.6 AJW70094.1 - 0.00052 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF3203 PF11462.8 AJW70094.1 - 0.0059 16.8 0.1 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3203) Mnd1 PF03962.15 AJW70094.1 - 0.0081 16.4 0.6 0.86 9.9 0.0 2.8 3 0 0 3 3 3 1 Mnd1 HTH domain HTH_24 PF13412.6 AJW70094.1 - 0.047 13.3 0.2 0.11 12.0 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AJW70094.1 - 0.072 13.1 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain CtsR_C PF17727.1 AJW70094.1 - 0.085 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain HTH_29 PF13551.6 AJW70094.1 - 0.094 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 AJW70094.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain AhpC-TSA PF00578.21 AJW70095.1 - 6.9e-22 77.7 0.1 8.9e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJW70095.1 - 2.4e-14 53.3 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AJW70095.1 - 1.1e-06 28.9 0.1 1.9e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AJW70095.1 - 0.00072 20.0 0.1 0.0012 19.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain T4_deiodinase PF00837.17 AJW70095.1 - 0.016 14.5 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_3 PF13192.6 AJW70095.1 - 0.022 14.8 0.3 0.19 11.8 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin domain Thioredoxin PF00085.20 AJW70095.1 - 0.043 13.8 0.1 1.4 8.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.6 AJW70095.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 F plasmid transfer operon protein SCO1-SenC PF02630.14 AJW70095.1 - 0.1 12.5 0.1 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 SCO1/SenC Zn_dep_PLPC PF00882.18 AJW70095.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C UPF0180 PF03698.13 AJW70096.1 - 0.019 15.2 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) MG2 PF01835.19 AJW70097.1 - 0.042 14.3 0.0 0.062 13.8 0.0 1.4 1 0 0 1 1 1 0 MG2 domain DUF5484 PF17583.2 AJW70097.1 - 0.11 12.1 0.4 0.11 12.1 0.4 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5484) DUF5129 PF17173.4 AJW70097.1 - 0.16 11.1 1.9 7.2 5.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) CTP_transf_like PF01467.26 AJW70098.1 - 2e-13 50.8 0.0 2.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 AJW70098.1 - 0.055 13.3 0.3 0.13 12.2 0.2 1.7 2 1 0 2 2 2 0 FAD synthetase zinc_ribbon_6 PF14599.6 AJW70100.1 - 0.44 10.6 10.9 1.1 9.4 5.1 3.4 3 1 1 4 4 4 0 Zinc-ribbon Lar_restr_allev PF14354.6 AJW70100.1 - 1.1 9.7 5.6 14 6.1 1.7 3.4 2 2 0 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 AJW70100.1 - 2.2 8.2 12.4 6 6.9 0.0 3.3 3 1 1 4 4 4 0 Putative transposase DNA-binding domain DUF1655 PF07868.11 AJW70101.1 - 0.077 13.1 1.8 0.44 10.6 1.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1655) Sial-lect-inser PF09264.10 AJW70101.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion tRNA-synt_1b PF00579.25 AJW70102.1 - 6.7e-30 104.4 0.0 1.2e-29 103.5 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 AJW70102.1 - 0.018 14.0 0.0 0.094 11.6 0.0 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_2d PF01409.20 AJW70103.1 - 5.3e-84 281.5 0.1 7e-84 281.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 AJW70103.1 - 1.1e-06 28.2 0.0 5.3e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 AJW70103.1 - 0.0021 18.0 0.1 0.015 15.3 0.1 2.1 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 AJW70103.1 - 0.037 13.1 0.2 0.094 11.8 0.1 1.7 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 AJW70104.1 - 1.2e-34 119.6 0.0 6.8e-34 117.2 0.0 1.9 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 AJW70104.1 - 5.1e-19 68.3 0.0 2.6e-12 46.8 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.17 AJW70104.1 - 2.2e-11 43.7 0.3 4.1e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 B3/4 domain tRNA-synt_2d PF01409.20 AJW70104.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Neurensin PF14927.6 AJW70105.1 - 0.00014 21.6 0.2 0.00016 21.4 0.2 1.0 1 0 0 1 1 1 1 Neurensin DUF898 PF05987.13 AJW70105.1 - 0.019 14.0 0.1 0.021 13.9 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) COPI_assoc PF08507.10 AJW70105.1 - 0.021 14.9 3.3 1.7 8.7 0.6 2.0 2 0 0 2 2 2 0 COPI associated protein DUF3185 PF11381.8 AJW70105.1 - 0.026 14.5 7.7 0.59 10.2 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Tetraspanin PF00335.20 AJW70105.1 - 0.03 14.0 0.7 0.036 13.8 0.7 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4418 PF14387.6 AJW70105.1 - 0.1 12.8 1.3 1 9.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) DUF2371 PF10177.9 AJW70105.1 - 0.24 11.6 3.2 0.91 9.7 3.2 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) PIRT PF15099.6 AJW70105.1 - 0.32 10.6 4.2 0.71 9.5 0.1 2.0 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family 7TM_GPCR_Srh PF10318.9 AJW70105.1 - 0.41 9.6 5.8 0.43 9.6 0.7 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh MLANA PF14991.6 AJW70105.1 - 1.3 9.3 4.9 18 5.6 1.9 2.1 2 0 0 2 2 2 0 Protein melan-A DUF3188 PF11384.8 AJW70105.1 - 4.8 7.0 10.4 1.8 8.3 1.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) Saf_2TM PF18303.1 AJW70105.1 - 6.6 6.3 10.1 5.2 6.7 3.1 2.0 1 1 0 2 2 2 0 SAVED-fused 2TM effector domain EVE PF01878.18 AJW70107.1 - 7.7e-40 136.2 0.3 8.7e-40 136.1 0.3 1.0 1 0 0 1 1 1 1 EVE domain HP1451_C PF18472.1 AJW70107.1 - 0.075 13.0 0.1 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 HP1451 C-terminal domain ATG11 PF10377.9 AJW70107.1 - 0.096 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 AsnC_trans_reg PF01037.21 AJW70108.1 - 5.3e-11 42.3 0.0 6.2e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJW70108.1 - 0.00066 19.7 0.0 0.00077 19.5 0.0 1.1 1 0 0 1 1 1 1 NapD protein Swi3 PF07962.12 AJW70109.1 - 0.16 12.0 1.4 12 6.0 0.1 2.8 2 1 1 3 3 3 0 Replication Fork Protection Component Swi3 F-box-like_2 PF13013.6 AJW70110.1 - 0.019 14.9 0.4 0.33 10.9 0.4 2.1 1 1 0 1 1 1 0 F-box-like domain Aconitase PF00330.20 AJW70111.1 - 2e-143 478.7 0.0 2.9e-143 478.2 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AJW70111.1 - 8.5e-36 123.2 0.1 5e-35 120.7 0.0 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.13 AJW70111.1 - 0.0093 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) UPF0228 PF05727.11 AJW70111.1 - 0.063 13.1 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) SOR_SNZ PF01680.17 AJW70113.1 - 7.5e-95 316.6 3.8 7.5e-95 316.6 3.8 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 AJW70113.1 - 5.2e-08 32.5 1.4 1.2e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AJW70113.1 - 0.00024 20.6 1.3 0.057 12.9 0.1 3.2 2 1 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 AJW70113.1 - 0.00086 18.5 0.4 0.6 9.1 0.1 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) OMPdecase PF00215.24 AJW70113.1 - 0.0011 18.6 0.4 0.22 11.1 0.0 2.6 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.15 AJW70113.1 - 0.0012 18.4 5.7 0.14 11.5 0.2 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 AJW70113.1 - 0.0029 16.8 0.0 0.068 12.3 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PA PF02225.22 AJW70113.1 - 0.089 12.8 0.3 3.4 7.7 0.1 2.4 2 0 0 2 2 2 0 PA domain Peptidase_S66C PF17676.1 AJW70113.1 - 0.091 13.3 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain NanE PF04131.14 AJW70113.1 - 0.11 11.7 3.4 0.71 9.0 0.0 3.0 2 2 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase SNO PF01174.19 AJW70114.1 - 6.5e-49 166.3 0.0 7.4e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AJW70114.1 - 1.1e-12 47.9 0.0 2.2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AJW70114.1 - 2.6e-12 46.9 0.1 2.3e-11 43.8 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 AJW70114.1 - 8.3e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.13 AJW70114.1 - 3e-05 23.9 0.0 0.00085 19.1 0.0 2.3 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 AJW70114.1 - 5.8e-05 23.0 0.0 0.00015 21.6 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family Caldesmon PF02029.15 AJW70115.1 - 3.2e-05 22.9 46.0 4e-05 22.6 46.0 1.1 1 0 0 1 1 1 1 Caldesmon OmpH PF03938.14 AJW70115.1 - 0.0043 17.4 16.8 0.0043 17.4 16.8 2.7 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 AJW70115.1 - 0.11 12.6 4.4 0.11 12.5 1.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 AJW70115.1 - 0.18 11.6 53.7 0.19 11.6 45.2 2.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain AAA_15 PF13175.6 AJW70115.1 - 0.29 10.8 38.7 0.43 10.2 38.7 1.3 1 0 0 1 1 1 0 AAA ATPase domain MRP-L51 PF10244.9 AJW70116.1 - 0.12 12.6 0.3 0.22 11.7 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit tRNA-synt_1 PF00133.22 AJW70117.1 - 2.1e-107 359.8 0.2 3.5e-106 355.8 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJW70117.1 - 1e-30 106.7 2.3 1e-30 106.7 2.3 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJW70117.1 - 1.1e-21 77.0 1.0 4.2e-12 45.5 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AJW70117.1 - 0.00066 19.2 0.0 0.16 11.5 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 PTPS PF01242.19 AJW70118.1 - 3.2e-19 69.1 0.1 9.4e-19 67.6 0.0 1.7 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase Pterin_4a PF01329.19 AJW70119.1 - 4.6e-32 110.0 0.3 5e-32 109.9 0.3 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 AJW70119.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Translation-initiation factor 2 Asn_synthase PF00733.21 AJW70120.1 - 1e-26 94.4 0.0 9.9e-20 71.5 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase NAD_synthase PF02540.17 AJW70120.1 - 1.6e-06 27.5 0.1 6.4e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 AJW70120.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.6 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AJW70120.1 - 0.035 13.9 0.3 0.18 11.5 0.3 2.3 1 1 0 1 1 1 0 PP-loop family Lyase_1 PF00206.20 AJW70121.1 - 1.4e-47 162.7 1.6 2.1e-47 162.0 1.6 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AJW70121.1 - 8.9e-14 51.8 0.0 2.1e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 AJW70121.1 - 0.0055 16.8 0.1 0.017 15.2 0.1 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal DUF3464 PF11947.8 AJW70122.1 - 0.26 11.0 0.3 0.25 11.1 0.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CBS PF00571.28 AJW70123.1 - 5.1e-25 87.7 6.2 3.2e-13 49.9 0.4 2.2 2 0 0 2 2 2 2 CBS domain Usp PF00582.26 AJW70124.1 - 4.8e-31 108.2 0.0 5.4e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Cactin_mid PF10312.9 AJW70125.1 - 0.062 13.0 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Conserved mid region of cactin MBF1 PF08523.10 AJW70126.1 - 0.0028 18.1 10.0 0.0036 17.7 10.0 1.2 1 0 0 1 1 1 1 Multiprotein bridging factor 1 Borrelia_P83 PF05262.11 AJW70126.1 - 0.62 8.5 12.5 0.64 8.4 12.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RtcB PF01139.17 AJW70127.1 - 1.3e-165 551.6 0.1 1.5e-165 551.4 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Complex1_LYR PF05347.15 AJW70127.1 - 0.077 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) dsDNA_bind PF01984.20 AJW70128.1 - 9.3e-09 35.5 0.7 1.2e-08 35.3 0.7 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.9 AJW70128.1 - 0.0033 17.9 2.7 0.0033 17.9 2.7 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_S11 PF00411.19 AJW70130.1 - 5e-42 142.8 2.1 6.9e-42 142.3 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 AJW70130.1 - 0.0038 17.5 0.1 0.0075 16.5 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) DUF4034 PF13226.6 AJW70131.1 - 0.22 10.8 0.0 0.24 10.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) AIRS PF00586.24 AJW70132.1 - 1.6e-12 47.9 0.0 2.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain TusA PF01206.17 AJW70132.1 - 0.089 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Sulfurtransferase TusA AIRS_C PF02769.22 AJW70132.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 AIR synthase related protein, C-terminal domain PGM_PMM_I PF02878.16 AJW70133.1 - 1.5e-23 83.1 0.0 3.8e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AJW70133.1 - 5.7e-14 52.3 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AJW70133.1 - 1.3e-11 45.0 0.0 2.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AJW70133.1 - 2.6e-07 30.7 0.0 7.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain B12-binding PF02310.19 AJW70133.1 - 0.027 14.5 0.0 1 9.4 0.0 2.4 1 1 0 1 1 1 0 B12 binding domain XK-related PF09815.9 AJW70137.1 - 0.09 11.8 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 XK-related protein Chordopox_A13L PF05961.11 AJW70137.1 - 0.17 12.1 0.1 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein FeoB_associated PF12669.7 AJW70137.1 - 0.42 11.1 0.4 0.42 11.1 0.4 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein TMEM154 PF15102.6 AJW70137.1 - 1.9 8.4 3.4 3.5 7.5 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family HTH_45 PF14947.6 AJW70138.1 - 3.7e-16 58.9 0.3 5.9e-16 58.2 0.1 1.4 2 0 0 2 2 2 1 Winged helix-turn-helix HTH_34 PF13601.6 AJW70138.1 - 0.00044 20.4 0.1 0.00063 19.9 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain RNA_pol_Rpc34 PF05158.12 AJW70138.1 - 0.00064 19.2 0.1 0.00075 19.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit DUF4364 PF14277.6 AJW70138.1 - 0.00084 19.1 0.1 0.0016 18.2 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4364) Rrf2 PF02082.20 AJW70138.1 - 0.002 18.4 0.1 0.0033 17.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator DUF505 PF04458.12 AJW70138.1 - 0.01 14.3 0.0 0.01 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Mrr_N PF14338.6 AJW70138.1 - 0.018 15.2 0.0 0.026 14.7 0.0 1.4 1 1 0 1 1 1 0 Mrr N-terminal domain Ribosomal_S19e PF01090.19 AJW70138.1 - 0.025 14.3 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e TrmB PF01978.19 AJW70138.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB dCache_3 PF14827.6 AJW70138.1 - 0.03 14.0 0.1 0.037 13.7 0.1 1.0 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase PadR PF03551.14 AJW70138.1 - 0.039 13.9 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family RPA_C PF08784.11 AJW70138.1 - 0.049 14.3 0.1 0.065 13.9 0.1 1.1 1 0 0 1 1 1 0 Replication protein A C terminal HTH_27 PF13463.6 AJW70138.1 - 0.083 13.4 0.0 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.22 AJW70138.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 MarR family FAM221 PF14753.6 AJW70139.1 - 0.00068 19.3 2.5 0.00095 18.8 2.5 1.2 1 0 0 1 1 1 1 Protein FAM221A/B DUF4428 PF14471.6 AJW70140.1 - 0.0034 17.3 4.3 0.0099 15.8 4.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4428) DiS_P_DiS PF06750.13 AJW70140.1 - 0.25 11.5 1.4 0.56 10.4 0.5 1.5 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain AIPR PF10592.9 AJW70141.1 - 1.2e-62 212.2 7.0 1.2e-62 212.2 7.0 2.2 2 1 0 2 2 2 1 AIPR protein Copper-bind PF00127.20 AJW70142.1 - 7.6e-09 35.9 0.6 3.5e-08 33.8 0.2 2.1 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW70142.1 - 2.5e-07 30.7 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Cupredoxin-like domain CBFD_NFYB_HMF PF00808.23 AJW70143.1 - 2.9e-13 49.9 0.2 3.4e-13 49.7 0.2 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 AJW70143.1 - 5.4e-05 23.5 0.0 6.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 AJW70143.1 - 0.00018 21.6 0.1 0.00021 21.4 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 AJW70143.1 - 0.0022 18.3 0.1 0.0027 18.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 AJW70143.1 - 0.0036 17.3 0.0 0.0043 17.1 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 AJW70143.1 - 0.0054 16.7 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 AJW70143.1 - 0.011 16.2 0.1 0.013 16.0 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF2120 PF09893.9 AJW70143.1 - 0.066 13.3 0.2 0.086 13.0 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) TatD_DNase PF01026.21 AJW70144.1 - 1.1e-43 149.5 0.0 1.2e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Ribosomal_S17e PF00833.18 AJW70145.1 - 2.4e-17 63.0 4.2 2.4e-17 63.0 4.2 1.3 1 1 0 1 1 1 1 Ribosomal S17 Osteoregulin PF07175.11 AJW70145.1 - 0.55 10.4 5.2 2.4 8.3 0.8 2.3 1 1 1 2 2 2 0 Osteoregulin LMBR1 PF04791.16 AJW70145.1 - 1.7 7.4 2.8 1.9 7.3 2.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein AIF-MLS PF14962.6 AJW70145.1 - 3 7.8 23.8 4 7.4 23.8 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence HSP9_HSP12 PF04119.12 AJW70145.1 - 5.1 7.6 6.4 19 5.7 1.1 2.9 1 1 0 2 2 2 0 Heat shock protein 9/12 ThiS PF02597.20 AJW70146.1 - 1.5e-07 32.0 0.0 5.3e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 ThiS family CGI-121 PF08617.10 AJW70146.1 - 0.00022 21.4 4.5 0.0004 20.6 4.5 1.5 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Urm1 PF09138.11 AJW70146.1 - 0.0037 17.6 2.7 0.0064 16.8 0.9 2.4 2 1 0 2 2 2 1 Urm1 (Ubiquitin related modifier) THUMP PF02926.17 AJW70147.1 - 3.5e-13 49.9 3.2 4e-13 49.7 3.2 1.2 1 0 0 1 1 1 1 THUMP domain DrrA_P4M PF14860.6 AJW70147.1 - 0.085 12.7 3.2 0.78 9.6 0.0 2.7 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Phos_pyr_kin PF08543.12 AJW70147.1 - 0.094 12.1 0.3 0.14 11.5 0.3 1.4 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase Sua5_yciO_yrdC PF01300.18 AJW70148.1 - 7.1e-49 165.7 0.0 8.1e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination FlbT PF07378.11 AJW70148.1 - 0.074 13.1 0.2 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Flagellar protein FlbT Carbam_trans_C PF16861.5 AJW70148.1 - 0.081 12.5 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus HTH_45 PF14947.6 AJW70150.1 - 5.7e-12 45.4 0.1 7.4e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 AJW70150.1 - 6.5e-08 32.4 0.0 8.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AJW70150.1 - 3.4e-05 23.6 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AJW70150.1 - 6.6e-05 22.7 0.0 8.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AJW70150.1 - 0.00047 19.7 0.1 0.00081 18.9 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJW70150.1 - 0.00089 19.1 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AJW70150.1 - 0.0009 19.7 0.1 0.0011 19.4 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.6 AJW70150.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Dimerisation2 PF16864.5 AJW70150.1 - 0.002 18.1 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Dimerisation domain RQC PF09382.10 AJW70150.1 - 0.0021 17.8 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 RQC domain DUF4194 PF13835.6 AJW70150.1 - 0.0037 17.0 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) DUF1495 PF07381.11 AJW70150.1 - 0.0048 16.7 0.0 0.006 16.4 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) HTH_20 PF12840.7 AJW70150.1 - 0.0087 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain RP-C PF03428.13 AJW70150.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain PadR PF03551.14 AJW70150.1 - 0.013 15.5 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Mrr_N PF14338.6 AJW70150.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.3 1 1 0 1 1 1 0 Mrr N-terminal domain Rrf2 PF02082.20 AJW70150.1 - 0.014 15.7 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 AJW70150.1 - 0.016 15.1 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RPA_C PF08784.11 AJW70150.1 - 0.02 15.6 0.0 0.034 14.8 0.0 1.4 1 1 0 1 1 1 0 Replication protein A C terminal Replic_Relax PF13814.6 AJW70150.1 - 0.022 14.8 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation HTH_34 PF13601.6 AJW70150.1 - 0.027 14.6 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Linker_histone PF00538.19 AJW70150.1 - 0.035 14.5 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family Ribosomal_S25 PF03297.15 AJW70150.1 - 0.053 13.7 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 S25 ribosomal protein B-block_TFIIIC PF04182.12 AJW70150.1 - 0.063 13.4 0.1 0.086 13.0 0.1 1.1 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.12 AJW70150.1 - 0.067 12.6 0.0 0.067 12.6 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Rio2_N PF09202.11 AJW70150.1 - 0.08 13.2 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 Rio2, N-terminal HxlR PF01638.17 AJW70150.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix FUR PF01475.19 AJW70150.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family DUF2250 PF10007.9 AJW70150.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_46 PF15977.5 AJW70150.1 - 0.12 12.3 0.7 0.19 11.8 0.6 1.4 1 1 0 1 1 1 0 Winged helix-turn-helix DNA binding DUF3021 PF11457.8 AJW70151.1 - 5 7.5 20.8 3.3 8.1 9.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) zf-TFIIB PF13453.6 AJW70152.1 - 0.019 14.3 0.5 0.14 11.5 1.5 1.9 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 AJW70152.1 - 0.037 13.9 5.4 0.53 10.2 5.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 AJW70152.1 - 0.061 13.3 0.4 0.072 13.1 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_6 PF14599.6 AJW70152.1 - 0.067 13.2 1.2 0.095 12.7 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon Mu-like_Com PF10122.9 AJW70152.1 - 0.085 12.3 1.0 6.7 6.2 0.7 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com Ribosomal_S27e PF01667.17 AJW70152.1 - 0.56 10.0 5.3 4.4 7.1 5.3 2.0 1 1 0 1 1 1 0 Ribosomal protein S27 zinc_ribbon_5 PF13719.6 AJW70152.1 - 2.5 8.0 5.9 13 5.6 5.9 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Iron_traffic PF04362.14 AJW70153.1 - 2.7e-07 30.2 0.2 3.7e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking OSTMP1 PF09777.9 AJW70153.1 - 0.032 13.6 0.5 0.037 13.4 0.5 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf_UBZ PF18439.1 AJW70153.1 - 0.26 10.9 2.5 0.54 9.9 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Annexin PF00191.20 AJW70154.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Annexin Adenylsucc_synt PF00709.21 AJW70155.1 - 1.4e-83 281.2 1.2 4.9e-41 141.0 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase OMPdecase PF00215.24 AJW70157.1 - 2e-25 89.8 0.0 2.4e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NUDIX PF00293.28 AJW70158.1 - 6.8e-20 71.4 0.3 7.9e-20 71.2 0.3 1.0 1 0 0 1 1 1 1 NUDIX domain Prenyltransf PF01255.19 AJW70159.1 - 4.6e-70 235.6 0.0 5.3e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF373 PF04123.13 AJW70160.1 - 7.8e-93 311.6 9.4 9.1e-93 311.3 9.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF4984 PF16372.5 AJW70160.1 - 0.0098 15.8 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4984) DUF4229 PF14012.6 AJW70160.1 - 6.7 6.9 7.1 21 5.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) AI-2E_transport PF01594.16 AJW70161.1 - 0.061 12.5 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 AI-2E family transporter Rol_Rep_N PF18106.1 AJW70162.1 - 0.0063 16.8 0.5 0.009 16.3 0.5 1.4 1 0 0 1 1 1 1 Rolling Circle replication initiation protein N-terminal domain DZR PF12773.7 AJW70163.1 - 0.027 14.5 2.0 0.044 13.8 2.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 AJW70163.1 - 0.047 13.7 0.4 0.052 13.6 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GFA PF04828.14 AJW70163.1 - 0.11 12.8 2.4 0.4 11.0 2.4 1.8 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 AJW70163.1 - 0.14 12.4 2.9 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_4 PF13717.6 AJW70163.1 - 0.55 10.2 6.3 2.9 7.9 6.2 1.9 1 1 0 1 1 1 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 AJW70164.1 - 2e-29 101.8 0.0 2.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 AJW70164.1 - 0.0016 18.7 0.3 0.0023 18.3 0.3 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 AJW70164.1 - 0.0029 17.1 0.6 0.005 16.3 0.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 AJW70164.1 - 0.013 15.6 0.2 0.022 14.8 0.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PDCD2_C PF04194.13 AJW70164.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain DUF295 PF03478.18 AJW70164.1 - 0.15 11.6 0.0 0.39 10.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF295) zf-TFIIB PF13453.6 AJW70164.1 - 0.68 9.3 4.2 0.24 10.8 1.6 1.6 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF424 PF04242.13 AJW70165.1 - 3.3e-23 81.8 0.3 3.7e-23 81.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) RIO1 PF01163.22 AJW70166.1 - 2.3e-53 180.6 0.0 3e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AJW70166.1 - 0.0043 17.0 0.0 2.8 7.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 AJW70166.1 - 0.0046 16.3 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 AJW70166.1 - 0.042 12.6 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase KH_1 PF00013.29 AJW70167.1 - 3e-11 43.0 6.4 5e-05 23.1 0.8 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 AJW70167.1 - 0.031 14.1 5.4 0.84 9.5 0.3 2.4 2 0 0 2 2 2 0 KH domain Topo-VIb_trans PF09239.11 AJW70168.1 - 3.5e-54 182.9 0.0 7e-54 182.0 0.0 1.5 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 AJW70168.1 - 1e-08 35.6 0.0 2.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AJW70168.1 - 2.9e-05 23.9 0.0 6.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TP6A_N PF04406.14 AJW70169.1 - 2.6e-14 52.9 0.0 4.5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.22 AJW70169.1 - 0.021 15.1 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 Toprim domain DUF2207 PF09972.9 AJW70170.1 - 0.023 13.5 0.4 0.029 13.1 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RseC_MucC PF04246.12 AJW70170.1 - 0.039 13.9 0.4 0.055 13.4 0.4 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Shisa PF13908.6 AJW70170.1 - 0.25 11.5 0.0 0.41 10.9 0.0 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator BaxI_1 PF12811.7 AJW70171.1 - 0.008 15.8 1.2 0.0087 15.6 1.2 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like Oleosin PF01277.17 AJW70171.1 - 0.012 15.3 2.4 0.012 15.4 2.4 1.1 1 0 0 1 1 1 0 Oleosin TrmB PF01978.19 AJW70172.1 - 2.2e-05 24.2 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MRF_C2 PF13888.6 AJW70173.1 - 0.0021 18.0 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 UBA_2 PF08587.11 AJW70174.1 - 0.016 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Rx_N PF18052.1 AJW70174.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Rx N-terminal domain PNP_UDP_1 PF01048.20 AJW70175.1 - 1.1e-46 158.9 0.0 1.3e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pribosyltran PF00156.27 AJW70176.1 - 6.3e-17 61.5 0.0 7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AJW70176.1 - 0.0034 16.9 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase MG2 PF01835.19 AJW70177.1 - 1e-22 80.4 0.0 3.1e-05 24.3 0.0 5.7 6 0 0 6 6 6 4 MG2 domain FlgD_ig PF13860.6 AJW70177.1 - 7e-06 25.8 3.3 2.9 7.8 0.0 6.2 7 1 0 7 7 7 2 FlgD Ig-like domain DUF4384 PF14326.6 AJW70177.1 - 0.00031 20.8 0.0 0.81 9.8 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4384) Big_6 PF17936.1 AJW70177.1 - 0.00067 19.9 0.1 0.25 11.7 0.0 4.3 4 0 0 4 4 4 1 Bacterial Ig domain Invasin_D3 PF09134.10 AJW70177.1 - 0.00089 19.5 2.2 0.95 9.8 0.8 4.4 4 1 1 5 5 5 1 Invasin, domain 3 bMG3 PF11974.8 AJW70177.1 - 0.059 13.4 0.0 10 6.2 0.0 3.7 4 0 0 4 4 4 0 Bacterial alpha-2-macroglobulin MG3 domain AAA_15 PF13175.6 AJW70178.1 - 4.8e-24 85.8 6.1 4.8e-24 85.8 6.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AJW70178.1 - 2.8e-14 53.6 6.5 2e-08 34.4 0.5 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AJW70178.1 - 0.0027 18.2 1.5 0.0082 16.7 0.0 2.4 2 1 0 2 2 2 1 ABC transporter DUF2813 PF11398.8 AJW70178.1 - 0.0043 16.4 0.1 0.92 8.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2813) AAA_29 PF13555.6 AJW70178.1 - 0.0078 15.9 0.1 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AJW70178.1 - 0.01 15.5 0.1 0.032 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Glyco_hydro_42C PF08533.10 AJW70178.1 - 0.019 14.7 0.1 0.84 9.4 0.0 2.9 2 1 1 3 3 3 0 Beta-galactosidase C-terminal domain SMC_N PF02463.19 AJW70178.1 - 0.072 12.5 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJW70178.1 - 1.1 9.7 25.3 0.38 11.2 15.1 4.1 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 AJW70178.1 - 1.4 8.0 10.9 0.7 9.0 3.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit Plasmodium_HRP PF05403.11 AJW70180.1 - 3.4e-05 23.8 1.3 4.6e-05 23.3 1.3 1.1 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) RNA_pol_Rpc34 PF05158.12 AJW70180.1 - 0.013 14.9 13.1 0.045 13.1 13.1 2.1 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF4573 PF15140.6 AJW70180.1 - 0.034 13.9 13.0 0.068 13.0 12.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) MarR PF01047.22 AJW70180.1 - 0.045 13.7 1.1 0.055 13.4 0.2 1.6 2 0 0 2 2 2 0 MarR family RPA_C PF08784.11 AJW70180.1 - 0.17 12.5 0.5 0.87 10.3 0.5 2.2 1 1 0 1 1 1 0 Replication protein A C terminal Ndc1_Nup PF09531.10 AJW70180.1 - 1.3 7.6 13.5 1.4 7.5 13.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC27 PF09507.10 AJW70180.1 - 2.2 7.6 48.4 2.7 7.3 48.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3807 PF12720.7 AJW70180.1 - 3.4 7.9 27.5 8 6.7 27.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) FtsJ PF01728.19 AJW70181.1 - 1.7e-51 174.8 0.0 2e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 AJW70181.1 - 0.00013 22.6 0.1 0.00066 20.3 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJW70181.1 - 0.00022 21.0 0.1 0.00056 19.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW70181.1 - 0.0039 17.1 0.0 0.0087 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AJW70181.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 AJW70181.1 - 0.048 13.0 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TRM PF02005.16 AJW70182.1 - 9.8e-80 268.5 0.0 1.1e-79 268.3 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 AJW70182.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Vps39_2 PF10367.9 AJW70182.1 - 0.1 13.0 0.8 0.42 11.1 0.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_3 PF13920.6 AJW70182.1 - 0.14 12.1 1.6 0.27 11.1 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNase_HII PF01351.18 AJW70183.1 - 5.6e-45 153.6 0.3 6.3e-45 153.4 0.3 1.0 1 0 0 1 1 1 1 Ribonuclease HII DUF2853 PF11015.8 AJW70183.1 - 0.21 12.3 2.7 0.18 12.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) Fibrillarin PF01269.17 AJW70184.1 - 5e-87 290.8 0.4 5e-87 290.8 0.4 3.0 2 1 0 2 2 2 1 Fibrillarin Methyltransf_25 PF13649.6 AJW70184.1 - 0.06 14.1 0.3 0.63 10.8 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain Nop PF01798.18 AJW70185.1 - 1.3e-64 217.8 0.0 1.7e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DHO_dh PF01180.21 AJW70186.1 - 1.5e-54 185.2 0.4 1.7e-54 185.0 0.4 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 AJW70186.1 - 5.5e-06 25.7 0.1 0.0015 17.7 0.1 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AJW70186.1 - 2.2e-05 24.0 0.2 0.0057 16.1 0.0 2.5 3 0 0 3 3 3 2 Histidine biosynthesis protein NMO PF03060.15 AJW70186.1 - 0.00017 21.1 0.2 0.00057 19.4 0.2 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase DUF561 PF04481.12 AJW70186.1 - 0.00058 19.1 5.4 0.00077 18.7 0.0 3.2 3 1 0 4 4 4 1 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 AJW70186.1 - 0.0011 18.4 0.5 0.68 9.3 0.0 2.5 3 0 0 3 3 3 2 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 AJW70186.1 - 0.0023 17.3 1.7 0.62 9.3 0.5 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 AJW70186.1 - 0.0024 16.9 0.3 0.0067 15.5 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NAD_binding_1 PF00175.21 AJW70187.1 - 3.9e-10 40.3 0.0 1.8e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 AJW70187.1 - 2.3e-08 33.7 8.3 5.3e-08 32.5 8.3 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 AJW70187.1 - 0.015 15.6 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AJW70187.1 - 0.051 13.7 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain SH3_17 PF18350.1 AJW70187.1 - 0.083 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease SH3 domain Radical_SAM PF04055.21 AJW70188.1 - 4.8e-10 40.1 0.0 9.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S30 PF04758.14 AJW70189.1 - 5.2e-11 42.6 3.6 7.9e-11 42.0 3.6 1.3 1 1 0 1 1 1 1 Ribosomal protein S30 Rad51 PF08423.11 AJW70191.1 - 7.3e-88 294.1 0.0 9.5e-88 293.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 AJW70191.1 - 5.2e-10 39.2 0.1 8e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 AJW70191.1 - 1.3e-09 38.5 0.1 4e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 AJW70191.1 - 1.1e-08 34.7 0.1 2.4e-08 33.6 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 AJW70191.1 - 3.3e-06 26.8 0.0 7.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AJW70191.1 - 0.0024 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AJW70191.1 - 0.022 15.3 0.1 0.097 13.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Radical_SAM PF04055.21 AJW70192.1 - 9.8e-19 68.3 0.1 2e-17 64.1 0.1 2.1 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 AJW70192.1 - 0.00062 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Ribosomal_L21e PF01157.18 AJW70193.1 - 3.7e-20 71.7 1.5 5.2e-20 71.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_pol_Rpb4 PF03874.16 AJW70194.1 - 9.4e-09 35.7 1.3 1.8e-08 34.7 1.3 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF4844 PF16133.5 AJW70194.1 - 0.0069 16.9 0.3 0.012 16.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4844) Integrase_Zn PF02022.19 AJW70194.1 - 0.17 11.9 0.0 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain DUF655 PF04919.12 AJW70195.1 - 1.7e-50 171.5 0.3 1.9e-50 171.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.6 AJW70195.1 - 7.2e-05 23.0 0.0 0.00017 21.8 0.0 1.7 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AJW70195.1 - 0.0045 17.2 0.0 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif RrnaAD PF00398.20 AJW70196.1 - 2e-40 138.5 3.6 2.8e-40 138.1 3.6 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 AJW70196.1 - 0.00035 20.4 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AJW70196.1 - 0.0018 19.0 0.0 0.0047 17.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJW70196.1 - 0.025 15.2 0.0 0.053 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 AJW70196.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 AJW70196.1 - 0.037 14.8 0.0 0.19 12.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 AJW70196.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AJW70196.1 - 0.04 13.8 0.0 0.053 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain RNase_H_2 PF13482.6 AJW70196.1 - 0.047 13.7 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 RNase_H superfamily DUF4919 PF16266.5 AJW70196.1 - 0.052 13.5 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) DUF5638 PF18688.1 AJW70196.1 - 0.12 12.7 2.5 0.14 12.5 0.4 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5638) Methyltransf_31 PF13847.6 AJW70197.1 - 2.6e-07 30.6 0.5 4.5e-07 29.8 0.5 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AJW70197.1 - 4.8e-07 29.5 0.0 1.5e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AJW70197.1 - 9.5e-07 28.8 0.0 4.1e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJW70197.1 - 8e-05 23.2 0.0 0.00014 22.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW70197.1 - 0.00044 20.9 0.1 0.0013 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AJW70197.1 - 0.00089 19.1 0.0 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 AJW70197.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.12 AJW70197.1 - 0.0014 19.4 0.1 0.0024 18.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AJW70197.1 - 0.0052 15.9 0.0 0.042 12.9 0.0 2.1 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 AJW70197.1 - 0.0052 16.8 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AJW70197.1 - 0.034 13.1 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 AJW70197.1 - 0.064 12.6 0.1 0.12 11.7 0.1 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 AJW70197.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 AJW70197.1 - 0.15 11.4 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Iso_dh PF00180.20 AJW70198.1 - 8.4e-83 278.4 0.2 9.9e-83 278.2 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.28 AJW70199.1 - 4e-18 66.7 0.2 6.1e-18 66.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJW70199.1 - 7.8e-16 58.7 0.0 1.2e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AJW70199.1 - 2e-05 24.1 0.3 0.0012 18.2 0.0 2.2 1 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily DUF2124 PF09897.9 AJW70199.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) OrfB_Zn_ribbon PF07282.11 AJW70200.1 - 0.0097 15.8 0.4 0.01 15.7 0.4 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-RING_4 PF14570.6 AJW70200.1 - 0.064 13.1 3.5 3.5 7.5 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_3 PF13878.6 AJW70200.1 - 0.21 11.4 1.3 1.5 8.7 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn-ribbon_8 PF09723.10 AJW70200.1 - 0.23 11.6 3.8 10 6.4 1.4 2.2 2 0 0 2 2 2 0 Zinc ribbon domain DivIC PF04977.15 AJW70201.1 - 0.00019 21.1 0.8 0.00022 20.9 0.8 1.1 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 AJW70201.1 - 0.0036 17.4 0.6 0.0053 16.8 0.5 1.4 1 1 0 1 1 1 1 bZIP transcription factor CCD48 PF15799.5 AJW70201.1 - 0.017 13.4 0.0 0.017 13.4 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 bZIP_2 PF07716.15 AJW70201.1 - 0.019 15.1 0.6 0.026 14.6 0.3 1.4 2 0 0 2 2 2 0 Basic region leucine zipper HAP1_N PF04849.13 AJW70201.1 - 0.023 13.9 0.2 0.023 13.9 0.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Mto2_bdg PF12808.7 AJW70201.1 - 0.028 14.7 0.3 0.039 14.3 0.3 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TSC22 PF01166.18 AJW70201.1 - 0.058 13.7 0.4 0.075 13.4 0.4 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family YabA PF06156.13 AJW70201.1 - 0.079 13.6 0.2 0.079 13.6 0.2 1.0 1 0 0 1 1 1 0 Initiation control protein YabA Transglut_core2 PF13369.6 AJW70202.1 - 1.5e-41 141.6 0.0 1.9e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 AJW70202.1 - 2.5e-15 56.4 0.0 3.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJW70202.1 - 0.00012 22.0 0.2 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 AJW70202.1 - 0.00043 20.0 0.4 0.13 12.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AJW70202.1 - 0.014 15.5 0.0 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat YfzA PF14118.6 AJW70202.1 - 0.07 13.5 0.0 2.3 8.7 0.1 2.3 2 0 0 2 2 2 0 YfzA-like protein NADPH_Ox PF08414.10 AJW70203.1 - 0.39 11.1 2.2 3.2 8.1 0.2 2.8 2 1 0 3 3 3 0 Respiratory burst NADPH oxidase Methyltransf_25 PF13649.6 AJW70204.1 - 6.5e-07 30.0 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJW70204.1 - 1.4e-05 25.6 0.0 2.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Trm112p PF03966.16 AJW70204.1 - 3.6e-05 24.2 0.6 0.00012 22.6 0.5 2.0 2 0 0 2 2 2 1 Trm112p-like protein Methyltransf_23 PF13489.6 AJW70204.1 - 0.00036 20.4 0.0 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Zn_Tnp_IS1595 PF12760.7 AJW70204.1 - 0.019 14.9 0.3 0.047 13.7 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CSL PF05207.13 AJW70204.1 - 0.02 14.6 0.6 0.037 13.8 0.6 1.4 1 0 0 1 1 1 0 CSL zinc finger RNA_POL_M_15KD PF02150.16 AJW70204.1 - 0.053 13.4 0.3 5.9 6.9 0.0 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Elf1 PF05129.13 AJW70204.1 - 0.054 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.6 AJW70204.1 - 0.064 13.0 1.2 0.13 12.0 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJW70204.1 - 0.26 10.8 0.2 0.26 10.8 0.2 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 AJW70204.1 - 0.48 10.4 2.0 1.2 9.1 2.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Cupredoxin_1 PF13473.6 AJW70205.1 - 5e-06 26.6 0.1 1e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Cupredoxin-like domain PKD PF00801.20 AJW70206.1 - 0.0076 16.1 0.3 0.0076 16.1 0.3 2.6 3 1 0 3 3 3 1 PKD domain Thioredoxin_3 PF13192.6 AJW70208.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Tmemb_9 PF05434.11 AJW70208.1 - 0.047 13.6 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 TMEM9 Band_7 PF01145.25 AJW70209.1 - 2.7e-23 82.9 7.1 4.1e-23 82.3 7.1 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family HxlR PF01638.17 AJW70210.1 - 0.013 15.3 0.1 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF2250 PF10007.9 AJW70210.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Cullin PF00888.22 AJW70210.1 - 0.037 12.7 0.0 0.041 12.5 0.0 1.0 1 0 0 1 1 1 0 Cullin family DUF4423 PF14394.6 AJW70210.1 - 0.039 13.7 0.1 0.091 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) TFIIE_alpha PF02002.17 AJW70210.1 - 0.049 13.5 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit DUF2830 PF11125.8 AJW70210.1 - 0.29 11.2 0.9 0.66 10.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) TFIIB PF00382.19 AJW70211.1 - 4e-29 100.5 7.5 1.3e-15 57.2 1.6 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW70211.1 - 6e-08 32.1 0.6 1.1e-07 31.3 0.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_AsnC-type PF13404.6 AJW70211.1 - 0.002 17.9 0.1 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain LacI PF00356.21 AJW70211.1 - 0.0032 17.2 1.7 2.4 8.0 0.1 3.2 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family Cyclin_N PF00134.23 AJW70211.1 - 0.0059 16.4 0.5 0.13 12.0 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.16 AJW70211.1 - 0.0063 16.0 0.0 0.29 10.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 AJW70211.1 - 0.007 16.3 0.8 0.15 12.0 0.0 2.6 2 0 0 2 2 2 1 HTH domain TetR_N PF00440.23 AJW70211.1 - 0.0073 16.1 0.3 0.28 11.0 0.1 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family RB_B PF01857.20 AJW70211.1 - 0.038 14.0 0.2 0.087 12.9 0.1 1.6 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_23 PF13384.6 AJW70211.1 - 0.049 13.4 0.4 1 9.3 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_31 PF13560.6 AJW70211.1 - 0.13 12.6 0.2 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AJW70211.1 - 0.14 11.8 1.1 0.91 9.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 FaeA PF04703.12 AJW70211.1 - 0.16 12.3 0.7 0.93 9.9 0.1 2.3 2 1 0 2 2 2 0 FaeA-like protein HrcA_DNA-bdg PF03444.15 AJW70211.1 - 0.18 11.5 1.4 3.6 7.3 0.0 2.7 3 0 0 3 3 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_Tnp_ISL3 PF13542.6 AJW70211.1 - 0.19 11.1 2.4 12 5.4 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 zinc_ribbon_2 PF13240.6 AJW70211.1 - 1.1 9.1 3.6 0.27 11.0 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 AJW70214.1 - 0.021 14.5 1.0 0.54 10.0 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain 5_nucleotid_C PF02872.18 AJW70215.1 - 5.5e-08 33.2 0.0 1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 AJW70215.1 - 7.7e-07 29.8 0.3 2.6e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF2971 PF11185.8 AJW70215.1 - 0.21 12.8 4.4 1.3 10.2 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2971) Response_reg PF00072.24 AJW70216.1 - 1.6e-23 83.0 0.1 1.9e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DEAD PF00270.29 AJW70217.1 - 6.9e-28 97.6 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AJW70217.1 - 2.3e-16 60.1 1.5 9.8e-15 54.9 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJW70217.1 - 1.1e-07 32.0 1.8 3e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1998 PF09369.10 AJW70217.1 - 1.2e-05 25.9 0.1 4.1e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) AAA_10 PF12846.7 AJW70217.1 - 0.042 12.8 0.1 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain MarR_2 PF12802.7 AJW70218.1 - 4.7e-07 29.6 0.0 9.6e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AJW70218.1 - 1e-06 28.7 0.0 6.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4423 PF14394.6 AJW70218.1 - 8.7e-06 25.5 0.5 2.9e-05 23.8 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4423) DUF505 PF04458.12 AJW70218.1 - 0.00031 19.3 0.0 0.00047 18.7 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF505) MarR PF01047.22 AJW70218.1 - 0.00033 20.5 1.0 0.082 12.8 0.1 2.3 2 0 0 2 2 2 2 MarR family HTH_45 PF14947.6 AJW70218.1 - 0.00034 20.5 0.5 0.0079 16.2 0.1 2.7 3 0 0 3 3 3 1 Winged helix-turn-helix TrmB PF01978.19 AJW70218.1 - 0.00041 20.2 0.1 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AJW70218.1 - 0.0005 20.0 0.2 0.0053 16.7 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AJW70218.1 - 0.0008 19.2 0.5 0.0022 17.8 0.0 2.1 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.9 AJW70218.1 - 0.0024 17.9 1.0 0.066 13.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_24 PF13412.6 AJW70218.1 - 0.0054 16.3 0.2 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 AJW70218.1 - 0.02 15.4 0.1 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 AJW70218.1 - 0.06 13.5 0.3 0.81 9.9 0.0 2.5 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC DUF3449 PF11931.8 AJW70218.1 - 0.061 13.1 0.4 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Mrr_N PF14338.6 AJW70218.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Mrr N-terminal domain Nitroreductase PF00881.24 AJW70219.1 - 2.1e-25 89.8 0.1 2.6e-13 50.4 0.0 2.6 2 1 1 3 3 3 2 Nitroreductase family TM1586_NiRdase PF14512.6 AJW70219.1 - 8.5e-08 32.0 0.3 0.0048 16.5 0.0 2.8 2 1 0 2 2 2 2 Putative TM nitroreductase DCP1 PF06058.13 AJW70219.1 - 0.0015 18.4 0.1 0.0081 16.1 0.1 2.2 2 0 0 2 2 2 1 Dcp1-like decapping family DUF1515 PF07439.11 AJW70220.1 - 0.16 12.0 0.2 0.16 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) MobA_MobL PF03389.15 AJW70222.1 - 0.2 11.4 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 MobA/MobL family HECT_2 PF09814.9 AJW70223.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Gln-synt_C PF00120.24 AJW70225.1 - 1.1e-117 393.0 0.0 1.4e-117 392.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AJW70225.1 - 2.4e-23 81.7 0.1 5.1e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4377 PF14302.6 AJW70228.1 - 1.8e-24 85.6 0.2 3.3e-24 84.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4377) Kazal_1 PF00050.21 AJW70228.1 - 2.7e-09 36.9 2.6 4e-09 36.4 1.2 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 AJW70228.1 - 3.6e-05 23.8 0.7 3.6e-05 23.8 0.7 2.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain O-ag_pol_Wzy PF14296.6 AJW70228.1 - 0.018 13.7 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy FOLN PF09289.10 AJW70228.1 - 0.42 10.8 0.1 0.42 10.8 0.1 2.9 2 1 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain DUF2674 PF10879.8 AJW70229.1 - 0.042 13.4 0.5 0.077 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) MetOD2 PF18548.1 AJW70229.1 - 0.077 13.1 0.5 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 Metanogen output domain 2 SnoaL_3 PF13474.6 AJW70230.1 - 0.00083 19.6 0.0 0.0016 18.7 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AJW70230.1 - 0.0083 15.9 0.1 0.026 14.3 0.1 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF2553 PF10830.8 AJW70230.1 - 0.029 15.2 0.6 2.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) DUF4867 PF16161.5 AJW70230.1 - 0.033 13.6 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4867) PAH PF02671.21 AJW70231.1 - 0.09 12.9 0.1 0.099 12.8 0.1 1.2 1 1 0 1 1 1 0 Paired amphipathic helix repeat SF-assemblin PF06705.11 AJW70232.1 - 0.047 13.0 1.7 3.5 6.9 0.6 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF2990 PF11693.8 AJW70232.1 - 0.1 12.7 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) ApoLp-III PF07464.11 AJW70232.1 - 0.33 11.0 4.0 1.1 9.3 0.1 2.2 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DegQ PF08181.11 AJW70232.1 - 0.41 10.8 5.6 10 6.3 0.3 3.3 3 0 0 3 3 3 0 DegQ (SacQ) family FidL_like PF15941.5 AJW70232.1 - 2.3 8.7 8.0 0.49 10.9 0.9 2.6 1 1 2 3 3 3 0 FidL-like putative membrane protein DUF302 PF03625.14 AJW70236.1 - 4e-18 65.1 0.0 7.4e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF302 BACK PF07707.15 AJW70236.1 - 0.16 12.1 0.1 0.95 9.6 0.0 1.9 2 0 0 2 2 2 0 BTB And C-terminal Kelch Rhodanese PF00581.20 AJW70237.1 - 2e-23 82.9 0.0 5.1e-13 49.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain HTH_20 PF12840.7 AJW70238.1 - 4.5e-07 29.8 0.0 5.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AJW70238.1 - 0.006 16.4 0.0 0.0089 15.8 0.0 1.4 1 1 0 1 1 1 1 IclR helix-turn-helix domain Pox_int_trans PF05718.12 AJW70238.1 - 0.021 13.6 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor TrmB PF01978.19 AJW70238.1 - 0.026 14.4 0.1 0.081 12.8 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.11 AJW70238.1 - 0.049 13.4 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF742) tRNA_anti-codon PF01336.25 AJW70238.1 - 0.056 13.4 0.1 0.067 13.2 0.1 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain UPF0444 PF15475.6 AJW70240.1 - 0.042 14.1 7.8 1.4 9.2 0.5 2.5 2 1 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 MFS18 PF17352.2 AJW70240.1 - 4.2 7.8 16.2 0.42 11.0 11.0 2.0 2 0 0 2 2 2 0 Male Flower Specific protein 18 Arginase PF00491.21 AJW70241.1 - 3.8e-60 203.8 0.0 4.8e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 AJW70241.1 - 0.003 17.8 0.1 0.0069 16.6 0.1 1.7 1 1 0 1 1 1 1 UPF0489 domain Urocanase_C PF17392.2 AJW70241.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Urocanase C-terminal domain Aldedh PF00171.22 AJW70242.1 - 3.7e-139 464.2 0.0 5.8e-139 463.6 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 AJW70243.1 - 1.4e-26 93.7 0.0 2.1e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase FeoB_associated PF12669.7 AJW70245.1 - 0.11 12.9 0.6 0.2 12.1 0.6 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein B2-adapt-app_C PF09066.10 AJW70245.1 - 0.14 12.3 0.0 5.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain CarboxypepD_reg PF13620.6 AJW70247.1 - 0.00029 21.0 0.1 0.00051 20.3 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SLC12 PF03522.15 AJW70247.1 - 0.47 9.4 10.5 0.67 8.9 10.5 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF4294 PF14127.6 AJW70248.1 - 0.015 15.2 4.2 0.025 14.5 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) His_Phos_2 PF00328.22 AJW70248.1 - 0.035 13.5 6.5 0.046 13.1 6.5 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) ALMT PF11744.8 AJW70248.1 - 0.13 11.1 3.5 0.14 10.9 3.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1474 PF07342.11 AJW70248.1 - 0.16 12.5 5.4 0.27 11.8 3.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1474) Cys_rich_CPCC PF14206.6 AJW70248.1 - 0.16 11.8 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 Cysteine-rich CPCC RGS PF00615.19 AJW70248.1 - 2.2 8.6 10.4 16 5.8 0.1 2.3 1 1 0 2 2 2 0 Regulator of G protein signaling domain LMBR1 PF04791.16 AJW70248.1 - 3.2 6.6 4.2 4.1 6.2 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MG2 PF01835.19 AJW70249.1 - 9.8e-19 67.6 0.1 0.00071 20.0 0.0 4.6 4 1 0 4 4 4 4 MG2 domain FlgD_ig PF13860.6 AJW70249.1 - 3.6e-05 23.6 0.4 0.083 12.8 0.0 4.2 3 1 0 4 4 4 2 FlgD Ig-like domain DUF4791 PF16039.5 AJW70250.1 - 0.014 15.0 0.3 0.017 14.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) DUF4199 PF13858.6 AJW70250.1 - 0.019 15.4 5.1 0.73 10.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Ndc1_Nup PF09531.10 AJW70250.1 - 0.032 12.9 1.5 0.036 12.8 1.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HRG PF16954.5 AJW70250.1 - 0.17 12.3 11.1 0.039 14.4 5.4 2.5 1 1 1 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF3989 PF13150.6 AJW70250.1 - 0.39 10.5 2.5 6.9 6.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3989) DUF2157 PF09925.9 AJW70250.1 - 0.55 10.0 5.1 0.71 9.6 5.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) HTH_24 PF13412.6 AJW70251.1 - 1.3e-18 66.3 0.3 4.2e-11 42.2 0.0 2.5 3 0 0 3 3 2 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AJW70251.1 - 4.8e-14 52.0 1.1 1.1e-08 34.8 0.3 2.5 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family TrmB PF01978.19 AJW70251.1 - 2.2e-11 43.5 0.0 8.3e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AJW70251.1 - 4.7e-11 42.6 0.0 8.8e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain MarR PF01047.22 AJW70251.1 - 3.7e-09 36.4 0.3 3.9e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 MarR family MarR_2 PF12802.7 AJW70251.1 - 1e-07 31.7 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 2 MarR family FaeA PF04703.12 AJW70251.1 - 1.8e-07 31.4 0.1 0.00032 21.0 0.0 3.0 2 1 1 3 3 3 1 FaeA-like protein HTH_11 PF08279.12 AJW70251.1 - 2.1e-07 30.8 0.0 0.00073 19.4 0.0 2.2 2 0 0 2 2 2 2 HTH domain HTH_IclR PF09339.10 AJW70251.1 - 6.6e-07 29.0 0.0 0.0059 16.4 0.0 2.2 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_34 PF13601.6 AJW70251.1 - 6.7e-07 29.4 0.4 0.0025 18.0 0.1 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AJW70251.1 - 8.4e-06 25.5 0.6 0.14 11.9 0.1 3.2 3 2 1 4 4 3 2 LexA DNA binding domain HTH_40 PF14493.6 AJW70251.1 - 3.6e-05 24.1 0.0 0.035 14.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AJW70251.1 - 5.1e-05 23.2 0.0 0.00064 19.6 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_27 PF13463.6 AJW70251.1 - 0.00011 22.7 0.0 0.0084 16.6 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain Sigma70_r4 PF04545.16 AJW70251.1 - 0.00015 21.2 0.0 0.00058 19.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 AJW70251.1 - 0.00016 21.5 0.0 0.00057 19.7 0.0 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain RepL PF05732.11 AJW70251.1 - 0.00016 21.2 0.0 0.018 14.5 0.0 2.3 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) GerE PF00196.19 AJW70251.1 - 0.00017 21.0 0.0 0.014 15.0 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Mga PF05043.13 AJW70251.1 - 0.00031 21.3 0.2 1.1 9.9 0.0 2.5 1 1 1 2 2 2 2 Mga helix-turn-helix domain Penicillinase_R PF03965.16 AJW70251.1 - 0.00092 19.5 1.7 0.0093 16.3 0.2 2.4 1 1 1 2 2 2 1 Penicillinase repressor HTH_9 PF08221.11 AJW70251.1 - 0.0012 18.9 0.1 0.0044 17.1 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_10 PF04967.12 AJW70251.1 - 0.0013 18.5 0.1 0.25 11.2 0.0 3.0 3 0 0 3 3 2 1 HTH DNA binding domain DprA_WH PF17782.1 AJW70251.1 - 0.0013 18.8 0.0 0.072 13.2 0.0 2.2 2 0 0 2 2 2 1 DprA winged helix domain Rrf2 PF02082.20 AJW70251.1 - 0.002 18.4 0.2 0.074 13.4 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator Sigma70_r4_2 PF08281.12 AJW70251.1 - 0.003 17.2 0.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_41 PF14502.6 AJW70251.1 - 0.0063 16.2 0.0 0.031 14.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Mga PF08280.11 AJW70251.1 - 0.0066 16.5 0.0 0.91 9.6 0.0 2.6 3 0 0 3 3 2 1 M protein trans-acting positive regulator (MGA) HTH domain BLACT_WH PF17778.1 AJW70251.1 - 0.0093 15.9 0.0 0.41 10.7 0.0 2.7 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain HTH_36 PF13730.6 AJW70251.1 - 0.0098 15.8 0.0 0.8 9.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Crp PF00325.20 AJW70251.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family LacI PF00356.21 AJW70251.1 - 0.019 14.7 0.0 0.063 13.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Dimerisation2 PF16864.5 AJW70251.1 - 0.019 14.9 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain Fe_dep_repress PF01325.19 AJW70251.1 - 0.022 14.9 0.2 0.78 10.0 0.0 2.5 2 1 1 3 3 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_38 PF13936.6 AJW70251.1 - 0.022 14.5 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain FUR PF01475.19 AJW70251.1 - 0.024 14.8 1.3 0.44 10.7 0.1 2.5 2 1 0 2 2 2 0 Ferric uptake regulator family HTH_45 PF14947.6 AJW70251.1 - 0.026 14.5 2.7 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix PaaX PF07848.12 AJW70251.1 - 0.029 14.6 0.0 5.7 7.2 0.0 2.4 2 1 0 2 2 2 0 PaaX-like protein HTH_29 PF13551.6 AJW70251.1 - 0.048 13.7 0.0 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_50 PF18024.1 AJW70251.1 - 0.091 12.4 0.0 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AJW70251.1 - 0.1 12.7 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix domain TetR_N PF00440.23 AJW70251.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Lip_prot_lig_C PF10437.9 AJW70251.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Rio2_N PF09202.11 AJW70251.1 - 0.17 12.1 1.2 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Rio2, N-terminal TSP_3 PF02412.18 AJW70252.1 - 4.7e-11 42.2 39.6 1.1e-05 25.0 4.6 3.8 3 0 0 3 3 3 3 Thrombospondin type 3 repeat DUF4763 PF15960.5 AJW70253.1 - 0.00036 19.9 0.9 0.00048 19.5 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) CorA PF01544.18 AJW70253.1 - 0.013 14.9 2.5 0.021 14.1 2.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2205 PF10224.9 AJW70253.1 - 0.058 13.4 2.6 0.18 11.8 2.6 1.8 1 1 0 1 1 1 0 Short coiled-coil protein DivIC PF04977.15 AJW70253.1 - 0.12 12.2 3.8 0.21 11.4 3.8 1.5 1 0 0 1 1 1 0 Septum formation initiator DNA_pol_phi PF04931.13 AJW70253.1 - 0.14 10.2 16.4 0.16 10.1 16.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 AJW70253.1 - 0.15 10.3 12.5 0.17 10.1 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family Med4 PF10018.9 AJW70253.1 - 0.16 11.7 3.8 0.2 11.3 3.8 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_2 PF07716.15 AJW70253.1 - 0.2 11.8 4.2 0.36 11.0 4.0 1.6 1 1 0 1 1 1 0 Basic region leucine zipper CDC45 PF02724.14 AJW70253.1 - 2.9 6.1 13.7 3.4 5.9 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein UPF0060 PF02694.15 AJW70254.1 - 2.3e-37 127.5 7.2 2.6e-37 127.3 7.2 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family MFS_1 PF07690.16 AJW70254.1 - 0.00019 20.5 5.9 0.0016 17.4 0.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PMT_2 PF13231.6 AJW70254.1 - 0.0043 17.3 0.3 0.16 12.1 0.1 2.1 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase EamA PF00892.20 AJW70254.1 - 0.0062 16.7 6.6 0.014 15.5 6.6 1.6 1 1 0 1 1 1 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 AJW70254.1 - 0.0098 15.8 6.0 0.029 14.3 6.0 1.7 1 1 0 1 1 1 1 7TM diverse intracellular signalling COX14 PF14880.6 AJW70254.1 - 0.21 11.5 0.6 0.48 10.3 0.6 1.8 1 1 0 1 1 1 0 Cytochrome oxidase c assembly DUF202 PF02656.15 AJW70254.1 - 0.24 11.9 3.9 29 5.2 3.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) UPF0060 PF02694.15 AJW70255.1 - 3.4e-40 136.6 9.5 4e-40 136.4 9.5 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Phage_holin_2_4 PF16082.5 AJW70255.1 - 0.0019 17.9 1.2 0.0019 17.9 1.2 1.6 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like EamA PF00892.20 AJW70255.1 - 0.0045 17.2 12.0 0.017 15.3 12.1 1.9 1 1 0 1 1 1 1 EamA-like transporter family BaxI_1 PF12811.7 AJW70255.1 - 0.021 14.4 4.3 0.026 14.1 4.3 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like MFS_1 PF07690.16 AJW70255.1 - 0.82 8.5 13.6 4.2 6.2 13.0 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF3611 PF12263.8 AJW70255.1 - 1.9 8.3 6.1 5.9 6.8 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) MaAIMP_sms PF16951.5 AJW70256.1 - 0.064 13.0 0.6 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit HTH_AsnC-type PF13404.6 AJW70258.1 - 4.9e-12 45.5 0.1 7e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJW70258.1 - 1.2e-11 44.0 0.3 2.1e-11 43.2 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AJW70258.1 - 5.4e-05 23.0 0.0 0.0003 20.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 AJW70258.1 - 0.00022 20.5 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF2250 PF10007.9 AJW70258.1 - 0.00096 19.2 0.2 0.0058 16.7 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.19 AJW70258.1 - 0.0011 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 AJW70258.1 - 0.0016 18.2 0.2 0.0021 17.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 AJW70258.1 - 0.0021 17.9 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AJW70258.1 - 0.0025 18.2 0.1 0.043 14.3 0.0 2.1 1 1 1 2 2 2 1 Winged helix DNA-binding domain Arc_trans_TRASH PF08394.10 AJW70258.1 - 0.0029 17.9 5.0 0.005 17.2 5.0 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain HTH_9 PF08221.11 AJW70258.1 - 0.0074 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2089 PF09862.9 AJW70258.1 - 0.0084 16.1 0.3 0.089 12.8 0.0 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF2089) FeoC PF09012.10 AJW70258.1 - 0.022 14.8 0.0 0.022 14.8 0.0 2.5 2 1 0 2 2 2 0 FeoC like transcriptional regulator MarR PF01047.22 AJW70258.1 - 0.03 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 AJW70258.1 - 0.056 13.3 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain zf-FCS PF06467.14 AJW70258.1 - 0.083 12.8 4.4 0.14 12.1 4.4 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HTH_38 PF13936.6 AJW70258.1 - 0.085 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AJW70258.1 - 0.089 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.19 AJW70258.1 - 0.14 11.8 1.0 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family DUF4396 PF14342.6 AJW70259.1 - 1.9e-31 109.3 4.8 2.4e-31 109.0 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF2062 PF09835.9 AJW70259.1 - 0.044 13.6 8.0 0.17 11.8 1.0 2.9 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) DoxX PF07681.12 AJW70261.1 - 3.8e-08 33.8 1.9 3.8e-08 33.8 1.9 2.0 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 AJW70261.1 - 2.2e-05 24.4 1.6 2.2e-05 24.4 1.6 1.6 2 0 0 2 2 2 1 TQO small subunit DoxD CitMHS PF03600.16 AJW70261.1 - 0.02 14.1 3.4 0.027 13.7 3.4 1.3 1 1 0 1 1 1 0 Citrate transporter DuoxA PF10204.9 AJW70261.1 - 0.024 13.7 1.3 0.035 13.1 1.3 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor VKG_Carbox PF05090.14 AJW70261.1 - 0.16 10.8 2.9 0.48 9.2 2.9 1.9 1 1 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF642 PF04862.12 AJW70263.1 - 2.2e-23 82.8 0.2 3.3e-23 82.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF642) CBM_4_9 PF02018.17 AJW70263.1 - 0.014 15.7 0.5 0.04 14.2 0.5 1.8 1 1 0 1 1 1 0 Carbohydrate binding domain FG-GAP PF01839.23 AJW70263.1 - 0.015 15.5 1.0 0.052 13.7 1.0 2.0 1 0 0 1 1 1 0 FG-GAP repeat Big_9 PF17963.1 AJW70264.1 - 2.6e-22 79.4 34.6 7.2e-19 68.3 12.1 4.5 2 2 1 3 3 3 2 Bacterial Ig domain Cadherin_5 PF17892.1 AJW70264.1 - 2.8e-17 62.5 17.8 8.1e-15 54.6 8.0 3.5 3 1 0 3 3 3 2 Cadherin-like domain Cadherin_4 PF17803.1 AJW70264.1 - 1.9e-16 60.5 32.1 3.3e-13 50.0 9.5 4.2 3 2 0 3 3 3 2 Bacterial cadherin-like domain TSP_3 PF02412.18 AJW70264.1 - 0.00011 21.9 6.4 0.00011 21.9 6.4 3.5 3 1 0 3 3 3 2 Thrombospondin type 3 repeat Cadherin_3 PF16184.5 AJW70264.1 - 0.00023 21.1 1.6 0.58 10.2 0.1 2.6 2 0 0 2 2 2 2 Cadherin-like HYR PF02494.16 AJW70265.1 - 3.4e-22 78.6 30.6 6.4e-11 42.4 2.6 4.5 4 0 0 4 4 4 3 HYR domain VWA PF00092.28 AJW70265.1 - 3.6e-19 69.7 5.2 3.6e-19 69.7 0.2 2.9 2 1 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 AJW70265.1 - 3.4e-13 50.1 5.3 1.9e-12 47.7 0.3 3.4 2 1 1 3 3 3 1 von Willebrand factor type A domain DUF4175 PF13779.6 AJW70265.1 - 0.0039 15.2 0.9 0.0068 14.4 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF4398 PF14346.6 AJW70265.1 - 0.17 12.5 8.2 0.067 13.8 5.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) DUF1837 PF08878.11 AJW70265.1 - 1.3 8.8 9.3 2.5 7.8 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) AAA_23 PF13476.6 AJW70265.1 - 1.6 9.2 6.2 3.3 8.2 6.2 1.4 1 0 0 1 1 1 0 AAA domain DUF2408 PF10303.9 AJW70265.1 - 5 7.7 8.6 1.4 9.5 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Sensor PF13796.6 AJW70267.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative sensor DHDPS PF00701.22 AJW70268.1 - 0.035 12.8 0.0 0.062 12.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family HTH_45 PF14947.6 AJW70270.1 - 0.00035 20.5 1.2 0.00043 20.2 1.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.22 AJW70270.1 - 0.039 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 MarR family SHOCT PF09851.9 AJW70271.1 - 0.0002 21.0 0.3 0.0004 20.0 0.3 1.6 1 0 0 1 1 1 1 Short C-terminal domain CcmH PF03918.14 AJW70271.1 - 0.025 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein GvpG PF05120.12 AJW70271.1 - 0.032 14.2 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 Gas vesicle protein G CemA PF03040.14 AJW70271.1 - 0.063 13.2 0.7 0.63 9.9 0.3 2.0 2 0 0 2 2 2 0 CemA family EMC3_TMCO1 PF01956.16 AJW70271.1 - 0.34 10.6 6.5 0.52 10.0 1.6 2.2 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SdpI PF13630.6 AJW70272.1 - 2.3 8.4 13.6 6.1 7.0 4.0 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family Cu-oxidase_3 PF07732.15 AJW70273.1 - 1.2e-24 86.5 3.3 3.1e-24 85.3 0.1 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AJW70273.1 - 1.2e-17 64.0 3.2 1.8e-05 24.5 0.0 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 AJW70273.1 - 1.3e-08 34.9 0.0 0.002 18.2 0.0 3.5 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.20 AJW70273.1 - 3e-07 30.8 3.1 0.00017 22.0 0.8 3.5 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase PF00394.22 AJW70273.1 - 4.7e-05 23.5 0.1 0.00069 19.8 0.0 2.4 2 1 1 3 3 3 1 Multicopper oxidase CopG_antitoxin PF12441.8 AJW70274.1 - 0.004 17.7 0.3 0.032 14.8 0.0 2.5 2 1 1 3 3 3 1 CopG antitoxin of type II toxin-antitoxin system RE_BstXI PF09552.10 AJW70274.1 - 0.021 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease HicB PF05534.12 AJW70274.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 HicB family HisKA_3 PF07730.13 AJW70275.1 - 0.19 12.2 0.0 1.3 9.6 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase AsnC_trans_reg PF01037.21 AJW70276.1 - 1.6e-08 34.4 0.0 2e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AJW70276.1 - 0.0021 18.1 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 NapD protein zf-C2H2_2 PF12756.7 AJW70277.1 - 9.5e-05 22.7 0.5 9.5e-05 22.7 0.5 1.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 AJW70277.1 - 0.00068 20.0 0.8 0.0013 19.0 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJW70277.1 - 0.0036 18.0 0.4 0.0072 17.1 0.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 AJW70277.1 - 0.018 15.4 0.2 0.043 14.2 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF629 PF04780.12 AJW70277.1 - 0.03 12.9 0.3 0.03 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) DUF2690 PF10901.8 AJW70277.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) zf-BED PF02892.15 AJW70277.1 - 0.12 12.4 1.8 0.2 11.7 1.8 1.5 1 1 0 1 1 1 0 BED zinc finger HTH_45 PF14947.6 AJW70278.1 - 1.1e-05 25.3 0.1 1.6e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.22 AJW70278.1 - 0.0003 20.6 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 AJW70278.1 - 0.053 13.7 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain SDA1 PF05285.12 AJW70283.1 - 0.0015 18.0 17.0 0.0018 17.7 17.0 1.0 1 0 0 1 1 1 1 SDA1 DUF4763 PF15960.5 AJW70283.1 - 0.0033 16.8 1.3 0.0047 16.3 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) CorA PF01544.18 AJW70283.1 - 0.025 13.9 4.1 0.046 13.0 4.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein bZIP_1 PF00170.21 AJW70283.1 - 0.06 13.4 2.7 0.1 12.7 2.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor AAA_11 PF13086.6 AJW70283.1 - 0.063 13.0 0.1 0.069 12.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.15 AJW70283.1 - 0.079 13.1 2.5 0.15 12.2 2.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper FlaC_arch PF05377.11 AJW70283.1 - 0.091 13.2 2.0 0.12 12.8 1.4 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Med4 PF10018.9 AJW70283.1 - 0.12 12.0 4.6 0.18 11.5 4.6 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIC PF04977.15 AJW70283.1 - 0.17 11.7 3.7 0.36 10.6 3.7 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF1818 PF08848.11 AJW70283.1 - 0.48 10.5 3.2 0.71 10.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) UPF0242 PF06785.11 AJW70283.1 - 4.4 7.4 10.4 8.9 6.4 10.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 AJW70284.1 - 0.027 14.5 8.1 2.3 8.3 0.5 3.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 AJW70284.1 - 0.46 8.4 9.5 0.026 12.5 3.9 1.6 2 0 0 2 2 2 0 Prominin Cupredoxin_1 PF13473.6 AJW70286.1 - 0.00012 22.2 0.0 0.00029 20.9 0.0 1.7 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 AJW70286.1 - 0.0025 18.2 0.1 0.012 16.0 0.1 2.2 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family EcpB_C PF18649.1 AJW70286.1 - 0.016 15.2 0.1 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 EcpB C-terminal domain BNR_2 PF13088.6 AJW70287.1 - 2e-07 30.6 0.1 0.013 14.8 0.1 4.4 1 1 2 3 3 3 3 BNR repeat-like domain Glyco_hydro_43 PF04616.14 AJW70287.1 - 2.3e-05 23.9 3.3 0.00025 20.4 0.1 2.8 2 1 1 3 3 3 2 Glycosyl hydrolases family 43 BNR PF02012.20 AJW70287.1 - 0.24 11.6 20.1 12 6.4 0.1 7.2 6 0 0 6 6 6 0 BNR/Asp-box repeat DUF624 PF04854.14 AJW70289.1 - 0.036 14.2 0.9 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 zf_C2H2_ZHX PF18387.1 AJW70291.1 - 0.0081 15.8 0.3 0.015 15.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_13 PF09855.9 AJW70291.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-H2C2_5 PF13909.6 AJW70291.1 - 0.027 14.2 0.4 0.052 13.3 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 AJW70291.1 - 0.042 14.7 1.2 0.095 13.6 1.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Phage_TAC_8 PF10666.9 AJW70291.1 - 0.053 13.8 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 zf-C2H2 PF00096.26 AJW70291.1 - 0.054 14.0 1.4 0.11 13.0 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type CCDC84 PF14968.6 AJW70293.1 - 0.15 11.7 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 FixQ PF05545.11 AJW70295.1 - 0.04 13.9 0.8 8 6.5 0.4 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CcmD PF04995.14 AJW70295.1 - 0.35 11.0 2.8 0.32 11.1 0.8 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2127 PF09900.9 AJW70295.1 - 3.8 7.8 13.8 0.51 10.6 8.8 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2127) RseC_MucC PF04246.12 AJW70295.1 - 5.7 6.9 7.7 7 6.6 1.9 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EIIBC-GUT_C PF07663.11 AJW70296.1 - 0.0056 16.8 0.5 0.0065 16.6 0.5 1.1 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II C-terminus SH PF01445.17 AJW70296.1 - 0.017 15.1 1.0 0.017 15.1 1.0 2.0 2 0 0 2 2 2 0 Viral small hydrophobic protein DUF4713 PF15831.5 AJW70296.1 - 0.23 11.9 1.8 0.26 11.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Diphthami_syn_2 PF01902.17 AJW70300.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Diphthamide synthase DUF1132 PF06575.12 AJW70302.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) BNR_6 PF15899.5 AJW70304.1 - 0.082 13.0 1.6 2.4 8.5 0.1 3.0 2 0 0 2 2 2 0 BNR-Asp box repeat BNR PF02012.20 AJW70304.1 - 0.17 12.0 4.1 12 6.3 0.0 4.2 4 0 0 4 4 4 0 BNR/Asp-box repeat zf-FCS PF06467.14 AJW70306.1 - 0.38 10.7 5.4 4 7.5 1.7 2.7 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif CBM_14 PF01607.24 AJW70309.1 - 0.0023 18.1 8.6 0.76 10.0 0.4 3.6 1 1 2 3 3 3 3 Chitin binding Peritrophin-A domain DUF4215 PF13948.6 AJW70309.1 - 5.1 7.6 10.4 7.3 7.1 2.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) Topoisom_I PF01028.20 AJW70312.1 - 2.8e-69 232.9 13.8 2.8e-69 232.9 13.8 2.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 AJW70312.1 - 3.7e-69 232.5 7.9 3.7e-69 232.5 7.9 3.0 2 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 AJW70312.1 - 2e-19 69.3 2.0 2e-19 69.3 2.0 4.4 3 2 0 4 4 4 1 C-terminal topoisomerase domain ketoacyl-synt PF00109.26 AJW70312.1 - 0.67 9.5 1.6 1.5 8.4 1.6 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain HD_assoc PF13286.6 AJW70312.1 - 0.82 10.2 5.0 0.27 11.8 0.6 2.4 2 0 0 2 2 2 0 Phosphohydrolase-associated domain FokI_N PF02981.15 AJW70312.1 - 5.9 7.1 7.7 1.4 9.1 0.1 2.9 3 0 0 3 3 3 0 Restriction endonuclease FokI, recognition domain adh_short PF00106.25 AJW70313.1 - 2.6e-53 180.4 0.0 3.2e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AJW70313.1 - 1e-38 133.2 0.0 1.4e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJW70313.1 - 1.1e-09 38.5 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AJW70313.1 - 8.7e-06 25.3 0.0 2.4e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 AJW70313.1 - 1.1e-05 25.2 0.1 0.0008 19.0 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family DHquinase_II PF01220.19 AJW70313.1 - 0.03 14.0 0.1 0.063 12.9 0.1 1.6 2 0 0 2 2 2 0 Dehydroquinase class II Eno-Rase_NADH_b PF12242.8 AJW70313.1 - 0.039 13.7 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DcuA_DcuB PF03605.14 AJW70313.1 - 0.07 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter NAD_binding_10 PF13460.6 AJW70313.1 - 0.18 11.7 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding DEAD PF00270.29 AJW70314.1 - 2.3e-34 118.7 0.4 6.7e-34 117.2 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AJW70314.1 - 7.2e-17 61.7 3.5 2.4e-14 53.6 0.6 4.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 AJW70314.1 - 7.2e-11 42.7 0.1 2.9e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) SNF2_N PF00176.23 AJW70314.1 - 0.024 13.4 0.0 0.044 12.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Citrate_bind PF16114.5 AJW70314.1 - 0.15 11.6 1.5 0.78 9.2 0.0 2.7 3 0 0 3 3 3 0 ATP citrate lyase citrate-binding N6_N4_Mtase PF01555.18 AJW70315.1 - 1.9e-37 129.2 3.5 2.3e-37 129.0 3.5 1.1 1 0 0 1 1 1 1 DNA methylase UPF0020 PF01170.18 AJW70315.1 - 0.001 18.8 0.0 0.12 12.1 0.0 2.4 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.15 AJW70315.1 - 0.0032 17.2 0.2 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase N6-adenineMlase PF10237.9 AJW70315.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase MT-A70 PF05063.14 AJW70315.1 - 0.063 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 MT-A70 MttA_Hcf106 PF02416.16 AJW70316.1 - 1.8e-09 36.8 1.0 2.9e-09 36.1 1.0 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family IFT20 PF14931.6 AJW70316.1 - 0.0033 17.6 0.5 0.0043 17.2 0.5 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF228 PF02989.14 AJW70316.1 - 0.0051 16.7 0.4 0.0057 16.5 0.4 1.1 1 0 0 1 1 1 1 Lyme disease proteins of unknown function DUF948 PF06103.11 AJW70316.1 - 0.0078 16.4 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF4389 PF14333.6 AJW70316.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) P-II PF00543.22 AJW70317.1 - 1.1e-16 61.2 3.3 2.8e-16 60.0 3.3 1.6 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II MFS_1 PF07690.16 AJW70318.1 - 1.3e-38 132.9 59.1 6.9e-31 107.5 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AJW70318.1 - 7.5e-12 45.2 20.0 1e-11 44.7 20.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Phage_holin_8 PF16931.5 AJW70318.1 - 0.00012 22.0 0.2 0.00012 22.0 0.2 2.2 2 1 1 3 3 3 1 Putative phage holin OATP PF03137.20 AJW70318.1 - 0.0078 14.5 14.1 0.36 9.1 4.0 3.5 1 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MASE2 PF05230.11 AJW70318.1 - 0.061 13.4 0.1 0.061 13.4 0.1 3.0 4 0 0 4 4 4 0 MASE2 domain GPI2 PF06432.11 AJW70318.1 - 0.42 10.0 6.8 0.84 9.0 3.1 2.7 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase YwiC PF14256.6 AJW70318.1 - 3.9 7.8 9.4 1.4 9.2 1.6 3.2 2 2 1 3 3 3 0 YwiC-like protein Ubie_methyltran PF01209.18 AJW70319.1 - 3.4e-18 65.8 0.0 4.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AJW70319.1 - 6.3e-13 49.2 0.0 9.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW70319.1 - 8.9e-11 42.4 0.0 1.3e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJW70319.1 - 3.5e-07 30.2 0.0 6.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW70319.1 - 5.9e-06 27.0 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW70319.1 - 2.6e-05 24.1 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AJW70319.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 AJW70319.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Proteasome PF00227.26 AJW70320.1 - 3.3e-50 170.2 0.9 4.3e-50 169.9 0.9 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AJW70320.1 - 2.1e-12 46.5 1.7 1.3e-10 40.8 0.2 2.5 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature HTH_5 PF01022.20 AJW70321.1 - 1.7e-10 40.6 1.0 2.7e-10 39.9 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AJW70321.1 - 3e-05 24.0 0.0 7.2e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_45 PF14947.6 AJW70321.1 - 0.004 17.1 0.2 0.008 16.1 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.22 AJW70321.1 - 0.006 16.5 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AJW70321.1 - 0.0064 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 AJW70321.1 - 0.0084 16.0 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain B-block_TFIIIC PF04182.12 AJW70321.1 - 0.01 16.0 0.3 0.018 15.2 0.1 1.6 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC MarR_2 PF12802.7 AJW70321.1 - 0.013 15.3 0.0 0.073 13.0 0.0 1.9 2 0 0 2 2 2 0 MarR family Phage_rep_org_N PF09681.10 AJW70321.1 - 0.023 14.6 0.4 0.035 14.0 0.4 1.3 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) HTH_24 PF13412.6 AJW70321.1 - 0.026 14.1 0.1 0.026 14.1 0.1 2.4 3 1 0 3 3 3 0 Winged helix-turn-helix DNA-binding BLOC1_2 PF10046.9 AJW70321.1 - 0.035 14.4 1.0 0.078 13.3 1.0 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ELFV_dehydrog PF00208.21 AJW70322.1 - 6e-69 232.5 2.2 8.4e-69 232.0 2.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AJW70322.1 - 3.2e-48 162.9 0.0 5.9e-48 162.0 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HTH_17 PF12728.7 AJW70322.1 - 0.11 12.7 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Toprim_4 PF13662.6 AJW70323.1 - 0.00018 21.9 0.0 0.0038 17.7 0.0 2.2 1 1 0 1 1 1 1 Toprim domain Toprim PF01751.22 AJW70323.1 - 0.00067 19.8 0.1 0.0024 18.1 0.1 1.8 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AJW70323.1 - 0.046 14.2 0.0 0.068 13.6 0.0 1.4 1 1 0 1 1 1 0 Toprim-like GATase PF00117.28 AJW70324.1 - 3.7e-20 72.5 0.0 5.3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJW70324.1 - 1.5e-06 28.1 0.0 4e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 HTS PF04204.16 AJW70324.1 - 2.1e-05 23.6 0.0 0.00012 21.1 0.0 1.8 2 0 0 2 2 2 1 Homoserine O-succinyltransferase GATase_3 PF07685.14 AJW70324.1 - 0.0096 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AJW70324.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Phage_integrase PF00589.22 AJW70325.1 - 1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family DUF16 PF01519.16 AJW70325.1 - 0.099 13.1 2.3 0.13 12.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 HxlR PF01638.17 AJW70326.1 - 3.3e-22 78.2 0.0 4.1e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AJW70326.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AJW70326.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_12 PF08461.10 AJW70326.1 - 0.027 14.4 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_24 PF13412.6 AJW70326.1 - 0.034 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJW70326.1 - 0.036 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 MarR family Replic_Relax PF13814.6 AJW70326.1 - 0.078 13.0 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation MtrA PF04208.14 AJW70326.1 - 0.13 11.9 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A HTH_Crp_2 PF13545.6 AJW70326.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF1788 PF08747.11 AJW70327.1 - 0.14 12.1 0.2 0.19 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) Baculo_PEP_C PF04513.12 AJW70328.1 - 1e-06 28.8 1.0 0.0017 18.4 0.1 2.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 AJW70328.1 - 9.4e-06 23.9 6.1 2.3e-05 22.6 5.6 1.7 1 1 1 2 2 2 1 Prominin CdvA PF18822.1 AJW70328.1 - 0.00015 21.6 9.1 0.066 13.0 2.6 3.0 2 1 0 3 3 2 2 CdvA-like coiled-coil domain AAA_13 PF13166.6 AJW70328.1 - 0.00016 20.5 3.5 0.00023 20.0 3.5 1.2 1 0 0 1 1 1 1 AAA domain DUF1640 PF07798.11 AJW70328.1 - 0.00074 19.6 6.4 0.0024 18.0 2.6 2.5 2 1 1 3 3 2 1 Protein of unknown function (DUF1640) TMPIT PF07851.13 AJW70328.1 - 0.0021 17.4 1.3 0.0035 16.6 1.3 1.4 1 0 0 1 1 1 1 TMPIT-like protein FTR_C PF02741.15 AJW70328.1 - 0.0021 18.1 7.4 0.027 14.5 3.6 2.3 1 1 0 2 2 2 1 FTR, proximal lobe Apolipoprotein PF01442.18 AJW70328.1 - 0.0029 17.5 0.0 0.0085 16.0 0.0 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF5082 PF16888.5 AJW70328.1 - 0.0032 17.7 12.5 1.8 8.9 7.6 4.1 2 1 2 4 4 3 1 Domain of unknown function (DUF5082) Tweety PF04906.13 AJW70328.1 - 0.0032 16.2 0.3 0.0051 15.5 0.3 1.2 1 0 0 1 1 1 1 Tweety TrbC PF04956.13 AJW70328.1 - 0.0043 17.3 0.1 5.1 7.4 0.0 2.6 2 0 0 2 2 2 0 TrbC/VIRB2 family Syntaxin-6_N PF09177.11 AJW70328.1 - 0.0056 17.2 10.4 1.2 9.8 4.9 3.4 2 1 1 3 3 2 1 Syntaxin 6, N-terminal SKA1 PF07160.12 AJW70328.1 - 0.0093 15.8 4.3 0.096 12.5 2.4 2.4 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 KxDL PF10241.9 AJW70328.1 - 0.0099 16.1 3.2 16 5.9 0.0 4.0 1 1 1 3 3 3 0 Uncharacterized conserved protein Fzo_mitofusin PF04799.13 AJW70328.1 - 0.015 14.9 1.3 4.4 6.8 2.8 2.6 1 1 1 2 2 2 0 fzo-like conserved region Fungal_trans_2 PF11951.8 AJW70328.1 - 0.017 14.0 0.1 0.024 13.5 0.1 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain HMMR_N PF15905.5 AJW70328.1 - 0.025 14.1 6.1 0.13 11.7 6.1 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3958 PF13125.6 AJW70328.1 - 0.028 14.6 3.8 0.036 14.3 0.7 2.5 3 1 0 3 3 2 0 Protein of unknown function (DUF3958) MtrG PF04210.13 AJW70328.1 - 0.03 14.2 2.3 0.03 14.2 2.3 3.0 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G ApoLp-III PF07464.11 AJW70328.1 - 0.039 14.0 10.5 0.12 12.5 0.4 2.6 2 1 1 3 3 2 0 Apolipophorin-III precursor (apoLp-III) APG17 PF04108.12 AJW70328.1 - 0.041 13.0 3.4 0.8 8.7 3.4 2.6 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF3450 PF11932.8 AJW70328.1 - 0.042 13.2 1.5 0.099 11.9 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 AJW70328.1 - 0.057 12.3 8.0 0.07 12.0 5.1 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein Img2 PF05046.14 AJW70328.1 - 0.063 13.6 9.1 1.6 9.1 0.9 3.6 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) PSS PF03034.15 AJW70328.1 - 0.063 13.0 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphatidyl serine synthase CHDCT2 PF08074.11 AJW70328.1 - 0.064 13.4 1.0 19 5.4 0.1 3.0 1 1 2 3 3 3 0 CHDCT2 (NUC038) domain GP41 PF00517.17 AJW70328.1 - 0.075 12.9 4.1 0.14 12.1 2.8 2.0 1 1 1 2 2 2 0 Retroviral envelope protein COG5 PF10392.9 AJW70328.1 - 0.11 12.7 6.0 2.3 8.4 0.5 3.0 2 1 1 3 3 2 0 Golgi transport complex subunit 5 LMBR1 PF04791.16 AJW70328.1 - 0.11 11.4 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 AJW70328.1 - 0.12 12.4 24.0 0.37 10.9 1.2 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) AAA_32 PF13654.6 AJW70328.1 - 0.14 10.9 5.8 0.37 9.5 5.3 1.7 1 1 1 2 2 2 0 AAA domain DUF948 PF06103.11 AJW70328.1 - 0.14 12.4 12.4 2.6 8.4 4.4 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 AJW70328.1 - 0.14 12.7 0.0 1.4 9.5 0.0 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) IMD PF08397.11 AJW70328.1 - 0.15 11.5 2.4 0.45 9.8 1.3 2.0 1 1 1 2 2 2 0 IRSp53/MIM homology domain Phage_lysis PF03245.13 AJW70328.1 - 0.17 12.1 0.9 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein HsbA PF12296.8 AJW70328.1 - 0.17 12.3 5.4 2.7 8.4 0.8 3.1 1 1 3 4 4 4 0 Hydrophobic surface binding protein A DASH_Dad1 PF08649.10 AJW70328.1 - 0.21 11.8 3.0 0.77 10.0 0.1 2.9 1 1 0 2 2 2 0 DASH complex subunit Dad1 Occludin_ELL PF07303.13 AJW70328.1 - 0.21 12.3 0.9 0.78 10.5 0.5 2.1 1 1 1 2 2 2 0 Occludin homology domain Fib_alpha PF08702.10 AJW70328.1 - 0.24 11.6 11.7 0.15 12.3 7.2 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family LPP PF04728.13 AJW70328.1 - 0.27 11.6 8.9 3.3e+02 1.7 8.6 4.2 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF677 PF05055.12 AJW70328.1 - 0.28 10.0 15.3 0.31 9.9 13.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF677) DUF4618 PF15397.6 AJW70328.1 - 0.3 10.5 0.0 0.3 10.5 0.0 2.6 2 1 0 3 3 2 0 Domain of unknown function (DUF4618) FAM76 PF16046.5 AJW70328.1 - 0.41 9.9 2.8 1.6 8.0 1.1 2.0 1 1 0 2 2 2 0 FAM76 protein Rx_N PF18052.1 AJW70328.1 - 0.45 10.8 5.5 11 6.4 1.2 3.5 2 1 0 3 3 2 0 Rx N-terminal domain REF PF05755.12 AJW70328.1 - 0.52 10.1 3.6 0.38 10.5 1.2 1.9 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) DUF2730 PF10805.8 AJW70328.1 - 0.54 10.4 9.6 1.6 8.9 1.1 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Phasin PF05597.11 AJW70328.1 - 0.59 10.1 7.6 12 5.9 5.3 2.8 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GLTP PF08718.11 AJW70328.1 - 0.6 10.4 1.8 3 8.1 1.8 2.3 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) TBCC_N PF16752.5 AJW70328.1 - 0.6 10.6 4.3 0.3 11.5 1.6 1.9 2 1 0 2 2 1 0 Tubulin-specific chaperone C N-terminal domain Cauli_AT PF03233.13 AJW70328.1 - 0.65 9.9 13.5 1.3 8.9 8.9 2.5 1 1 2 3 3 3 0 Aphid transmission protein Syntaxin PF00804.25 AJW70328.1 - 0.66 9.6 11.5 2.3 7.8 7.7 3.0 2 1 1 3 3 3 0 Syntaxin Cluap1 PF10234.9 AJW70328.1 - 0.78 9.1 4.8 2.2 7.6 4.8 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 YgaB PF14182.6 AJW70328.1 - 0.79 10.1 6.4 1.3 9.5 3.8 2.6 1 1 1 2 2 2 0 YgaB-like protein ISG65-75 PF11727.8 AJW70328.1 - 0.84 8.8 7.0 20 4.3 5.2 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein Mt_ATP-synt_D PF05873.12 AJW70328.1 - 0.99 9.2 5.9 11 5.8 5.5 2.6 1 1 2 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) ACCA PF03255.14 AJW70328.1 - 1.2 9.0 4.1 36 4.2 4.1 2.5 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Allexi_40kDa PF05549.11 AJW70328.1 - 1.3 8.4 4.2 2.7 7.4 4.1 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein End3 PF12761.7 AJW70328.1 - 1.9 8.6 7.2 37 4.4 7.0 3.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 HN PF00423.19 AJW70328.1 - 2.3 6.9 9.6 0.041 12.7 2.2 1.9 3 0 0 3 3 2 0 Haemagglutinin-neuraminidase BORCS7 PF16088.5 AJW70328.1 - 2.3 8.5 11.0 0.1 12.8 4.9 1.9 3 0 0 3 3 1 0 BLOC-1-related complex sub-unit 7 DUF724 PF05266.14 AJW70328.1 - 2.4 7.9 6.6 10 5.9 6.1 2.1 2 1 1 3 3 2 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 AJW70328.1 - 2.9 8.2 16.5 4.4 7.7 6.2 3.8 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 AJW70328.1 - 3.2 8.5 5.8 2.7 8.7 3.5 2.2 2 1 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) LXG PF04740.12 AJW70328.1 - 3.2 7.4 11.3 2 8.1 7.4 2.4 2 1 0 2 2 2 0 LXG domain of WXG superfamily zf-C4H2 PF10146.9 AJW70328.1 - 5.4 7.3 9.1 9.8 6.4 8.6 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein DUF3818 PF12825.7 AJW70328.1 - 7.5 5.5 9.6 5.4 5.9 2.5 2.4 1 1 1 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) DUF3852 PF12963.7 AJW70328.1 - 8.3 6.8 10.2 3.9 7.9 0.1 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF3852) FlaC_arch PF05377.11 AJW70328.1 - 8.7 6.8 27.0 46 4.5 10.6 5.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) NOP19 PF10863.8 AJW70331.1 - 0.028 14.3 0.4 0.039 13.8 0.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 19 HTH_45 PF14947.6 AJW70332.1 - 0.00013 21.9 0.3 0.00017 21.5 0.3 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.6 AJW70332.1 - 0.00075 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJW70332.1 - 0.0053 16.7 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 MarR family Peptidase_M10 PF00413.24 AJW70333.1 - 6.5e-05 22.8 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin DUF4784 PF16023.5 AJW70334.1 - 0.0014 17.6 0.2 0.0021 17.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4784) Mycobact_memb PF05423.13 AJW70334.1 - 0.43 10.5 2.5 2.8 7.9 0.2 2.2 1 1 1 2 2 2 0 Mycobacterium membrane protein DUF3139 PF11337.8 AJW70336.1 - 0.048 14.3 2.4 0.083 13.5 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) PIG-Y PF15159.6 AJW70337.1 - 0.007 17.3 0.3 0.007 17.3 0.3 2.0 2 1 0 2 2 2 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF4179 PF13786.6 AJW70339.1 - 0.18 12.3 1.3 0.67 10.5 1.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) CBM_14 PF01607.24 AJW70341.1 - 6.5e-05 23.0 4.7 0.46 10.7 0.3 3.5 1 1 2 3 3 3 3 Chitin binding Peritrophin-A domain DUF4215 PF13948.6 AJW70341.1 - 0.65 10.5 5.3 3.5 8.2 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4215) DUF3139 PF11337.8 AJW70342.1 - 0.022 15.4 1.2 0.32 11.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) 7TM_GPCR_Srw PF10324.9 AJW70342.1 - 0.022 14.0 0.2 0.16 11.3 0.1 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Rer1 PF03248.13 AJW70342.1 - 0.048 13.4 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 Rer1 family DUF5643 PF18705.1 AJW70343.1 - 2.3e-07 30.8 0.1 5.2e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5643) CDC48_N PF02359.18 AJW70343.1 - 1.1e-06 28.7 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Molydop_binding PF01568.21 AJW70343.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Pik1 PF11522.8 AJW70343.1 - 0.13 12.3 0.3 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Gag_p10 PF02337.17 AJW70344.1 - 0.023 14.6 0.0 0.085 12.8 0.0 1.8 1 1 1 2 2 2 0 Retroviral GAG p10 protein ATP-grasp_5 PF13549.6 AJW70347.1 - 1.2e-67 227.6 0.4 1.8e-67 227.1 0.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AJW70347.1 - 1.5e-48 164.1 0.3 3.9e-48 162.7 0.3 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJW70347.1 - 1e-25 90.5 0.0 4.2e-25 88.5 0.0 2.1 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.10 AJW70347.1 - 2.4e-08 33.8 0.4 5.1e-08 32.7 0.4 1.7 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 AJW70347.1 - 4e-08 33.8 0.4 1.8e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 CoA binding domain ATP-grasp PF02222.22 AJW70347.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain TPP_enzyme_M PF00205.22 AJW70347.1 - 0.056 13.2 0.4 1.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain GFO_IDH_MocA PF01408.22 AJW70347.1 - 0.11 13.3 0.0 0.28 12.0 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ECH_1 PF00378.20 AJW70348.1 - 2.5e-68 230.1 0.7 2.8e-68 229.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AJW70348.1 - 1.1e-39 136.9 0.3 9.7e-37 127.2 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Copper-bind PF00127.20 AJW70349.1 - 8e-09 35.8 0.0 1.8e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW70349.1 - 4.8e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 2 1 0 2 2 2 1 Cupredoxin-like domain HTH_20 PF12840.7 AJW70350.1 - 0.00023 21.1 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain FUR PF01475.19 AJW70350.1 - 0.00036 20.7 0.2 0.00044 20.4 0.2 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 AJW70350.1 - 0.0015 18.3 0.1 0.0027 17.5 0.1 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Hpr_kinase_N PF02603.16 AJW70350.1 - 0.0072 16.4 0.3 0.0099 15.9 0.3 1.2 1 0 0 1 1 1 1 HPr Serine kinase N terminus HTH_IclR PF09339.10 AJW70350.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain RP-C PF03428.13 AJW70350.1 - 0.094 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain Fe-S_biosyn PF01521.20 AJW70351.1 - 6.6e-23 81.0 0.0 7.4e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Toprim_4 PF13662.6 AJW70352.1 - 4.3e-07 30.3 0.2 9.4e-07 29.2 0.2 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AJW70352.1 - 6.9e-05 23.2 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 AJW70352.1 - 0.0091 16.2 0.1 0.024 14.8 0.1 1.8 1 0 0 1 1 1 1 Toprim domain CTP-dep_RFKase PF01982.16 AJW70353.1 - 1.3e-41 141.5 0.0 2e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF120 HTH_36 PF13730.6 AJW70353.1 - 0.055 13.4 1.9 0.069 13.1 0.7 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_rep_O PF04492.13 AJW70353.1 - 0.059 14.0 1.5 2.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage replication protein O CTP_transf_like PF01467.26 AJW70354.1 - 9.7e-13 48.5 0.0 1.8e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HTH_45 PF14947.6 AJW70354.1 - 0.00016 21.6 0.4 0.0003 20.7 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix TP_methylase PF00590.20 AJW70355.1 - 3.9e-18 66.2 0.0 2.3e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.13 AJW70355.1 - 1.9e-14 53.5 0.1 4.9e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF357) Ala_racemase_C PF00842.21 AJW70355.1 - 0.087 12.6 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain Peptidase_M20 PF01546.28 AJW70356.1 - 5.6e-29 101.3 0.1 9.2e-29 100.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AJW70356.1 - 9e-14 51.3 0.2 1.9e-13 50.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 AJW70356.1 - 3.5e-05 23.0 0.3 0.18 10.8 0.1 2.3 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase RimK PF08443.11 AJW70357.1 - 2.9e-27 95.5 0.0 3.9e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AJW70357.1 - 6.1e-07 29.6 0.0 9.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.16 AJW70357.1 - 1.7e-06 27.5 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AJW70357.1 - 7.9e-05 22.0 0.1 0.1 11.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.17 AJW70357.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AJW70357.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 AJW70357.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain zinc_ribbon_4 PF13717.6 AJW70358.1 - 5.5e-07 29.4 3.3 0.00098 19.0 0.9 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zf-RING_7 PF02591.15 AJW70358.1 - 0.00012 22.2 0.9 0.0032 17.6 0.1 2.2 2 0 0 2 2 2 1 C4-type zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 AJW70358.1 - 0.00017 21.4 8.6 0.0017 18.3 4.2 1.9 1 1 1 2 2 2 2 PhnA Zinc-Ribbon zf_UBZ PF18439.1 AJW70358.1 - 0.00029 20.4 2.7 0.24 11.0 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 AJW70358.1 - 0.00054 19.8 2.2 0.00091 19.1 2.2 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zinc_ribbon_5 PF13719.6 AJW70358.1 - 0.0006 19.5 0.5 0.048 13.4 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AJW70358.1 - 0.0011 19.0 1.7 0.0017 18.5 1.7 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_9 PF14369.6 AJW70358.1 - 0.0014 18.8 0.9 0.0021 18.3 0.9 1.2 1 0 0 1 1 1 1 zinc-ribbon zf-HYPF PF07503.12 AJW70358.1 - 0.0035 17.1 1.8 0.023 14.4 1.8 1.9 1 1 0 1 1 1 1 HypF finger zf-C4_Topoisom PF01396.19 AJW70358.1 - 0.0039 16.9 1.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger BssC_TutF PF08201.11 AJW70358.1 - 0.0049 16.9 0.6 0.14 12.2 0.1 2.0 2 0 0 2 2 2 1 BssC/TutF protein zf-ribbon_3 PF13248.6 AJW70358.1 - 0.0065 15.8 0.5 0.13 11.7 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 AJW70358.1 - 0.0092 16.0 0.5 0.013 15.5 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 AJW70358.1 - 0.0099 15.9 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 AJW70358.1 - 0.013 15.2 0.6 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.13 AJW70358.1 - 0.016 14.9 2.4 0.053 13.2 2.4 1.8 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit UPF0547 PF10571.9 AJW70358.1 - 0.023 14.7 3.9 1.5 8.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ADK_lid PF05191.14 AJW70358.1 - 0.029 14.4 0.2 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid CpXC PF14353.6 AJW70358.1 - 0.033 14.2 1.3 0.42 10.7 0.1 2.0 1 1 1 2 2 2 0 CpXC protein zinc-ribbons_6 PF07191.12 AJW70358.1 - 0.055 13.5 0.8 0.093 12.7 0.8 1.4 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_2 PF13240.6 AJW70358.1 - 0.059 13.1 3.1 0.91 9.3 3.1 2.2 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AJW70358.1 - 0.12 12.3 0.3 0.16 11.9 0.3 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CSL PF05207.13 AJW70358.1 - 0.14 11.9 2.1 0.23 11.2 2.0 1.5 1 1 1 2 2 2 0 CSL zinc finger DUF983 PF06170.12 AJW70358.1 - 0.14 12.6 0.4 2.7 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF1451 PF07295.11 AJW70358.1 - 0.14 12.2 0.8 0.18 11.8 0.8 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-C2H2 PF00096.26 AJW70358.1 - 0.22 12.1 0.6 4 8.1 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type PADR1 PF08063.12 AJW70358.1 - 0.26 11.1 3.2 0.95 9.3 0.1 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain zf-C2H2_4 PF13894.6 AJW70358.1 - 0.29 12.1 1.2 2.3 9.3 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 AJW70358.1 - 0.6 10.2 0.2 0.6 10.2 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ACC PF17848.1 AJW70358.1 - 0.72 10.0 7.1 6.1 7.0 0.4 2.4 3 0 0 3 3 2 0 Acetyl-coA carboxylase zinc finger domain zf-H2C2_2 PF13465.6 AJW70358.1 - 0.87 10.1 2.7 2.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain HMGL-like PF00682.19 AJW70359.1 - 3.2e-67 226.9 0.0 4.4e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 HMGL-like DUF5486 PF17588.2 AJW70359.1 - 0.12 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) HTH_AsnC-type PF13404.6 AJW70360.1 - 5.3e-13 48.6 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 AJW70360.1 - 6.8e-12 45.2 0.2 9.6e-12 44.7 0.2 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJW70360.1 - 8.5e-12 44.4 0.1 1.4e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding NapD PF03927.13 AJW70360.1 - 0.002 18.1 0.8 0.0036 17.3 0.8 1.5 1 0 0 1 1 1 1 NapD protein MarR_2 PF12802.7 AJW70360.1 - 0.0049 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 MarR family ACT_4 PF13291.6 AJW70360.1 - 0.0062 17.1 0.1 5.3 7.7 0.1 2.2 2 0 0 2 2 2 2 ACT domain Sigma70_r4 PF04545.16 AJW70360.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_11 PF08279.12 AJW70360.1 - 0.016 15.1 0.5 0.038 13.9 0.1 1.9 2 0 0 2 2 2 0 HTH domain Mga PF05043.13 AJW70360.1 - 0.018 15.6 0.0 0.032 14.8 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_5 PF01022.20 AJW70360.1 - 0.024 14.5 0.0 0.097 12.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR PF01047.22 AJW70360.1 - 0.025 14.5 0.2 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 AJW70360.1 - 0.052 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_9 PF08221.11 AJW70360.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.19 AJW70360.1 - 0.063 13.2 1.0 0.87 9.5 0.1 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB DDRGK PF09756.9 AJW70360.1 - 0.083 12.5 1.0 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 DDRGK domain HTH_Tnp_ISL3 PF13542.6 AJW70360.1 - 0.087 12.3 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 SCO1-SenC PF02630.14 AJW70360.1 - 0.087 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 SCO1/SenC HTH_DeoR PF08220.12 AJW70360.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain FeoC PF09012.10 AJW70360.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator Aminotran_3 PF00202.21 AJW70361.1 - 2.1e-117 392.3 0.0 2.4e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AJW70361.1 - 0.0002 20.7 0.0 0.0022 17.2 0.0 1.9 1 1 1 2 2 2 1 Aminotransferase class I and II DUF2931 PF11153.8 AJW70361.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) AA_kinase PF00696.28 AJW70362.1 - 1.7e-38 132.6 3.4 1.9e-38 132.4 3.4 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF4947 PF16305.5 AJW70362.1 - 0.053 13.5 0.1 0.089 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Semialdhyde_dh PF01118.24 AJW70363.1 - 6e-35 120.3 0.0 9.5e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AJW70363.1 - 3.3e-17 63.2 0.0 6.4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Sacchrp_dh_NADP PF03435.18 AJW70363.1 - 0.00015 22.1 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 AJW70363.1 - 0.00034 20.7 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 AJW70363.1 - 0.0026 18.5 0.0 0.0049 17.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RimK PF08443.11 AJW70364.1 - 1.5e-31 109.5 0.0 2e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 AJW70364.1 - 4.5e-10 39.2 0.1 2.4e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 AJW70364.1 - 1.3e-08 34.4 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp PF02222.22 AJW70364.1 - 9.7e-08 31.8 0.0 8.7e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AJW70364.1 - 3.4e-07 30.5 0.1 1.2e-06 28.7 0.1 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AJW70364.1 - 2.6e-06 26.9 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp GARS_A PF01071.19 AJW70364.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 AJW70364.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 AJW70364.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 AJW70364.1 - 0.023 14.1 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJW70364.1 - 0.023 14.2 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus zinc_ribbon_4 PF13717.6 AJW70365.1 - 9.2e-06 25.5 0.4 0.04 13.9 0.0 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.6 AJW70365.1 - 8.2e-05 22.3 0.4 0.044 13.5 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-TFIIB PF13453.6 AJW70365.1 - 0.00031 20.0 0.6 0.11 11.8 0.1 2.1 2 0 0 2 2 2 2 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 AJW70365.1 - 0.00041 19.6 1.5 0.39 10.2 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 AJW70365.1 - 0.00095 19.0 0.4 0.0014 18.4 0.4 1.2 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 AJW70365.1 - 0.00099 18.6 2.2 0.0012 18.3 2.2 1.4 1 1 0 1 1 1 1 TFIIB zinc-binding UPF0547 PF10571.9 AJW70365.1 - 0.0011 19.0 2.8 0.19 11.9 0.3 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zf-RING_7 PF02591.15 AJW70365.1 - 0.0054 16.9 1.8 0.15 12.2 0.1 2.3 2 0 0 2 2 2 1 C4-type zinc ribbon domain YacG PF03884.14 AJW70365.1 - 0.0056 16.4 0.6 0.8 9.5 0.0 2.2 2 0 0 2 2 2 1 DNA gyrase inhibitor YacG HypA PF01155.19 AJW70365.1 - 0.0059 16.6 0.3 0.0065 16.5 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ogr_Delta PF04606.12 AJW70365.1 - 0.0079 16.2 0.3 1.1 9.3 0.0 2.1 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger zf_UBZ PF18439.1 AJW70365.1 - 0.0091 15.6 1.6 1.1 8.9 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C4_Topoisom PF01396.19 AJW70365.1 - 0.0094 15.7 1.3 2 8.3 0.1 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Lar_restr_allev PF14354.6 AJW70365.1 - 0.012 16.0 0.4 0.015 15.7 0.4 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.13 AJW70365.1 - 0.013 15.1 2.8 0.64 9.8 0.2 2.7 1 1 2 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.10 AJW70365.1 - 0.015 15.0 1.6 2 8.2 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 AJW70365.1 - 0.018 15.0 0.5 0.059 13.4 0.5 1.8 1 1 0 1 1 1 0 zinc-ribbons Zn_Tnp_IS1 PF03811.13 AJW70365.1 - 0.018 14.7 0.5 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain zf-HYPF PF07503.12 AJW70365.1 - 0.021 14.6 1.6 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 HypF finger DZR PF12773.7 AJW70365.1 - 0.022 14.8 0.3 0.032 14.3 0.3 1.3 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 AJW70365.1 - 0.025 14.8 3.5 0.07 13.4 3.5 1.7 1 1 0 1 1 1 0 zinc-ribbon CpXC PF14353.6 AJW70365.1 - 0.032 14.3 0.4 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 AJW70365.1 - 0.032 14.3 3.4 0.72 10.0 0.2 2.0 1 1 0 2 2 2 0 Zinc ribbon domain Cys_rich_CPXG PF14255.6 AJW70365.1 - 0.038 13.9 0.4 4.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG DNA_ligase_ZBD PF03119.16 AJW70365.1 - 0.039 14.0 3.1 4.9 7.3 0.1 2.6 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Prok-RING_1 PF14446.6 AJW70365.1 - 0.047 13.6 5.5 0.1 12.5 5.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.21 AJW70365.1 - 0.066 13.5 0.3 0.081 13.2 0.3 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Anti-TRAP PF15777.5 AJW70365.1 - 0.1 12.6 1.7 0.21 11.6 1.7 1.6 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-ACC PF17848.1 AJW70365.1 - 0.12 12.5 3.0 4.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF1451 PF07295.11 AJW70365.1 - 0.13 12.3 0.3 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-C2H2_4 PF13894.6 AJW70365.1 - 0.15 12.9 0.4 7 7.8 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger PhnA_Zn_Ribbon PF08274.12 AJW70365.1 - 0.16 12.0 3.8 3.5 7.7 0.1 2.2 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf-IS66 PF13005.7 AJW70365.1 - 0.2 12.1 2.7 4.3 7.8 0.3 2.3 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 PADR1 PF08063.12 AJW70365.1 - 0.52 10.1 3.0 2 8.3 0.1 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain DUF983 PF06170.12 AJW70365.1 - 1.4 9.4 2.6 5.8 7.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Rubredoxin PF00301.20 AJW70365.1 - 1.9 8.6 5.9 6.9 6.8 0.5 2.4 1 1 1 2 2 2 0 Rubredoxin Arginosuc_synth PF00764.19 AJW70366.1 - 5.3e-159 529.7 0.2 6e-159 529.5 0.2 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 AJW70366.1 - 1.8e-05 24.6 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AJW70366.1 - 0.00033 20.2 0.1 0.00058 19.4 0.1 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AJW70366.1 - 0.12 12.1 0.1 0.28 10.9 0.1 1.5 1 1 0 1 1 1 0 PP-loop family NMT1_2 PF13379.6 AJW70367.1 - 3.4e-28 99.0 0.0 4.9e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AJW70367.1 - 2.4e-11 44.0 0.0 3.4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AJW70367.1 - 4.4e-06 26.5 0.0 6.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein ABC_tran PF00005.27 AJW70368.1 - 3.9e-31 108.4 0.0 7.2e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJW70368.1 - 9.7e-09 35.4 0.0 0.0042 16.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AJW70368.1 - 0.002 18.6 0.4 0.021 15.2 0.4 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AJW70368.1 - 0.0092 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AJW70368.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 AJW70368.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 AJW70368.1 - 0.017 14.8 0.0 0.18 11.5 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 AJW70368.1 - 0.018 14.5 0.4 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AJW70368.1 - 0.028 14.7 0.0 0.087 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AJW70368.1 - 0.034 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AJW70368.1 - 0.04 14.3 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AJW70368.1 - 0.045 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AJW70368.1 - 0.054 13.2 0.2 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 AJW70368.1 - 0.064 13.0 0.0 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AJW70368.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AJW70368.1 - 0.065 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AJW70368.1 - 0.066 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain VASP_tetra PF08776.11 AJW70368.1 - 0.074 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 VASP tetramerisation domain RNA_helicase PF00910.22 AJW70368.1 - 0.079 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 AJW70368.1 - 0.098 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AJW70368.1 - 0.1 12.5 0.1 0.36 10.7 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 AJW70368.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AJW70368.1 - 0.17 12.1 0.1 0.36 11.1 0.0 1.9 2 1 0 2 2 1 0 AAA domain BPD_transp_1 PF00528.22 AJW70369.1 - 3.6e-21 75.7 16.7 6.7e-21 74.9 16.7 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Phage_holin_2_1 PF04971.12 AJW70369.1 - 0.015 15.3 1.2 0.015 15.3 1.2 2.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S Mso1_Sec1_bdg PF14475.6 AJW70370.1 - 0.094 12.3 0.4 0.16 11.6 0.4 1.4 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Cu-oxidase_2 PF07731.14 AJW70371.1 - 8.1e-08 32.1 7.5 5.6e-07 29.4 6.1 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 AJW70371.1 - 0.081 12.9 5.0 0.061 13.3 0.7 2.5 2 0 0 2 2 2 0 Multicopper oxidase MFS_1 PF07690.16 AJW70372.1 - 8.8e-27 93.9 44.9 1.4e-24 86.7 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AJW70372.1 - 0.0031 16.4 34.3 0.0042 16.0 30.7 2.5 1 1 1 2 2 2 1 MFS_1 like family DUF4094 PF13334.6 AJW70372.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) MTHFR PF02219.17 AJW70373.1 - 0.0028 17.0 0.0 0.0035 16.7 0.0 1.3 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase NUDIX PF00293.28 AJW70374.1 - 2.1e-11 44.0 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_L39 PF00832.20 AJW70375.1 - 2.7e-18 65.3 6.9 3.1e-18 65.1 6.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.18 AJW70375.1 - 0.087 12.9 1.1 0.097 12.7 1.1 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ribosomal_L31e PF01198.19 AJW70376.1 - 2.2e-17 63.1 0.5 3.1e-17 62.6 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CBM_4_9 PF02018.17 AJW70376.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain Tubulin PF00091.25 AJW70377.1 - 2.2e-15 57.4 1.2 1.8e-14 54.4 0.1 2.3 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Radical_SAM PF04055.21 AJW70378.1 - 2.6e-19 70.2 0.0 3.8e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 AJW70378.1 - 1.1e-15 57.4 0.9 1.6e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 zf-PARP PF00645.18 AJW70378.1 - 0.0047 17.8 0.4 0.013 16.4 0.4 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Levi_coat PF01819.17 AJW70378.1 - 0.0049 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Levivirus coat protein Lyase_1 PF00206.20 AJW70379.1 - 3.6e-85 286.1 1.7 5e-85 285.6 1.7 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AJW70379.1 - 5.8e-14 52.3 0.0 1.3e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus DUF1062 PF06353.12 AJW70379.1 - 0.14 13.0 0.1 0.7 10.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1062) Cu-oxidase_3 PF07732.15 AJW70380.1 - 1.3e-08 34.8 0.6 1.3e-07 31.6 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase E1-E2_ATPase PF00122.20 AJW70380.1 - 0.043 13.3 0.4 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 E1-E2 ATPase 2-Hacid_dh_C PF02826.19 AJW70381.1 - 2.9e-62 209.2 0.1 5.6e-62 208.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AJW70381.1 - 5.3e-30 103.8 0.3 6e-30 103.6 0.3 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AJW70381.1 - 0.00046 20.4 0.5 0.0027 17.9 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase LXG PF04740.12 AJW70381.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 LXG domain of WXG superfamily DUF5305 PF17231.2 AJW70382.1 - 0.077 12.4 2.5 5.7 6.3 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Ribosomal_L15e PF00827.17 AJW70385.1 - 8.6e-46 156.1 2.6 1e-45 155.8 2.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Gram_pos_anchor PF00746.21 AJW70386.1 - 5.4 7.1 6.3 0.58 10.2 0.6 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif AhpC-TSA PF00578.21 AJW70388.1 - 3.1e-08 33.6 0.2 8.1e-06 25.8 0.0 2.4 2 2 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 AJW70388.1 - 9.3e-07 28.7 0.1 0.00041 20.1 0.0 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin_8 PF13905.6 AJW70388.1 - 0.014 15.7 0.3 4.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 AJW70388.1 - 0.073 13.5 0.2 0.53 10.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain AbiJ_NTD5 PF18865.1 AJW70388.1 - 0.09 12.6 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Response_reg PF00072.24 AJW70389.1 - 6.1e-24 84.3 0.2 7.2e-24 84.1 0.2 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HEAT_2 PF13646.6 AJW70390.1 - 6.2e-25 87.4 0.0 6.6e-14 52.1 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 AJW70390.1 - 7e-16 57.0 0.1 0.0055 16.8 0.0 4.2 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.16 AJW70390.1 - 4.2e-13 48.6 0.0 8.5e-05 22.9 0.1 3.5 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 AJW70390.1 - 2.3e-10 40.7 0.0 0.038 14.5 0.0 4.0 4 0 0 4 4 4 3 HEAT-like repeat Cnd1 PF12717.7 AJW70390.1 - 1.1e-07 32.0 0.1 6.3e-05 23.1 0.0 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 AJW70390.1 - 0.00037 19.2 0.0 0.00084 18.0 0.0 1.5 1 1 1 2 2 2 1 Adaptin N terminal region Arm PF00514.23 AJW70390.1 - 0.0013 18.7 0.0 0.64 10.1 0.0 3.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF2019 PF09450.10 AJW70390.1 - 0.0034 17.3 0.1 0.46 10.4 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF2019) Copper-bind PF00127.20 AJW70391.1 - 5.6e-18 65.2 2.4 8.3e-08 32.6 0.4 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW70391.1 - 1.6e-12 47.5 0.0 7.3e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain Kazal_1 PF00050.21 AJW70391.1 - 2.4e-10 40.3 0.4 8.5e-10 38.5 0.4 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 AJW70391.1 - 3.4e-06 27.1 0.5 8.1e-06 25.9 0.5 1.7 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Trypan_PARP PF05887.11 AJW70391.1 - 0.00057 19.9 23.3 0.0016 18.4 12.9 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) PKD PF00801.20 AJW70391.1 - 0.37 10.7 6.7 1.1 9.1 2.3 2.8 2 1 0 2 2 2 0 PKD domain TonB_N PF16031.5 AJW70391.1 - 4.8 7.7 24.9 2.6 8.5 2.2 2.3 2 0 0 2 2 2 0 TonB polyproline region SMC_N PF02463.19 AJW70392.1 - 2.5e-15 56.5 26.8 4.1e-09 36.2 1.3 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AJW70392.1 - 3.8e-15 56.5 51.2 2.2e-11 44.1 24.3 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AJW70392.1 - 5.1e-14 53.2 40.9 5.1e-14 53.2 40.9 4.3 1 1 2 3 3 1 1 AAA domain AAA_21 PF13304.6 AJW70392.1 - 3.4e-10 40.2 10.7 7.5e-06 26.0 0.3 2.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AJW70392.1 - 3.2e-09 36.4 0.2 6.4e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 AJW70392.1 - 5.6e-06 26.5 0.1 1.2e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 AJW70392.1 - 1.1e-05 25.2 1.6 1.1e-05 25.2 1.6 2.6 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 AJW70392.1 - 0.0022 18.5 28.4 0.0092 16.5 0.1 5.4 2 1 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 AJW70392.1 - 0.018 14.9 0.1 0.018 14.9 0.1 3.5 3 0 0 3 3 3 0 RsgA GTPase DNA_ligase_ZBD PF03119.16 AJW70392.1 - 0.039 14.0 0.1 0.091 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Sec23_trunk PF04811.15 AJW70392.1 - 0.042 13.4 0.8 0.14 11.7 0.4 2.0 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain MukB PF04310.12 AJW70392.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.0 3 1 1 4 4 4 0 MukB N-terminal MMR_HSR1 PF01926.23 AJW70392.1 - 5.9 7.0 6.6 0.77 9.9 0.1 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF948 PF06103.11 AJW70392.1 - 8 6.8 11.8 25 5.2 0.2 4.2 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) Metallophos_2 PF12850.7 AJW70393.1 - 5e-09 36.6 0.1 8.6e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AJW70393.1 - 3.5e-08 34.2 2.1 6e-08 33.4 2.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1798 PF08807.10 AJW70393.1 - 0.014 15.6 0.2 0.037 14.2 0.2 1.7 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF87 PF01935.17 AJW70394.1 - 4.9e-37 128.2 3.4 4.9e-37 128.2 3.4 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain DUF853 PF05872.12 AJW70394.1 - 6.6e-05 21.7 0.1 0.026 13.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) HAS-barrel PF09378.10 AJW70394.1 - 0.00067 19.8 0.1 0.002 18.2 0.1 1.9 1 0 0 1 1 1 1 HAS barrel domain TrwB_AAD_bind PF10412.9 AJW70394.1 - 0.024 13.6 0.7 0.056 12.3 0.1 1.9 2 1 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 AJW70394.1 - 0.039 14.3 0.0 0.13 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF4709 PF15821.5 AJW70394.1 - 0.047 14.0 0.9 0.16 12.3 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) ABC_tran PF00005.27 AJW70394.1 - 0.089 13.3 1.4 0.21 12.1 1.4 1.7 1 1 0 1 1 1 0 ABC transporter Baculo_RING PF05883.11 AJW70394.1 - 0.092 12.7 0.1 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain NurA PF09376.10 AJW70395.1 - 4.3e-17 62.6 0.1 5.8e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 NurA domain OpuAC PF04069.12 AJW70395.1 - 0.055 13.0 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system DUF108 PF01958.18 AJW70398.1 - 6.4e-32 109.8 0.8 1.1e-31 109.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 AJW70398.1 - 3.1e-14 53.6 0.0 4.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AJW70398.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AJW70398.1 - 0.0028 18.2 0.1 0.0078 16.8 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AJW70398.1 - 0.027 14.7 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 AJW70398.1 - 0.044 14.6 0.0 0.18 12.7 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 AJW70398.1 - 0.068 13.1 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NadA PF02445.16 AJW70399.1 - 1.4e-113 379.0 3.6 1.6e-113 378.8 3.6 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein TPR_1 PF00515.28 AJW70400.1 - 1.1e-13 50.4 1.7 5.3e-06 26.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AJW70400.1 - 3e-11 42.5 0.2 2.8e-05 23.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AJW70400.1 - 3.3e-11 43.2 7.9 2.5e-06 27.6 1.2 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AJW70400.1 - 2.6e-09 36.5 3.6 0.0012 18.8 0.1 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJW70400.1 - 8.5e-07 29.4 0.0 1.7e-05 25.2 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJW70400.1 - 1.3e-06 28.0 0.0 0.0089 16.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJW70400.1 - 4.6e-05 23.4 3.3 0.007 16.4 0.3 3.1 1 1 2 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 AJW70400.1 - 7.3e-05 23.3 0.0 0.00057 20.5 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AJW70400.1 - 0.00011 22.4 0.0 0.0035 17.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 AJW70400.1 - 0.0002 21.5 0.2 1.5 9.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AJW70400.1 - 0.00098 19.7 0.0 0.47 11.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 AJW70400.1 - 0.0012 19.4 0.0 2.3 9.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4919 PF16266.5 AJW70400.1 - 0.0015 18.5 1.4 0.012 15.6 0.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4919) TPR_11 PF13414.6 AJW70400.1 - 0.019 14.6 0.8 0.019 14.6 0.8 2.4 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 AJW70400.1 - 0.021 15.0 0.0 0.37 11.0 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Prefoldin PF02996.17 AJW70400.1 - 0.026 14.4 2.6 0.055 13.4 0.3 2.0 1 1 1 2 2 2 0 Prefoldin subunit Pec_lyase PF09492.10 AJW70400.1 - 0.034 13.5 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Pectic acid lyase YfiO PF13525.6 AJW70400.1 - 0.063 13.0 0.7 1.2 8.9 0.0 2.0 1 1 1 2 2 2 0 Outer membrane lipoprotein QRPTase_C PF01729.19 AJW70401.1 - 7.5e-55 185.3 1.6 1e-54 184.9 1.6 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AJW70401.1 - 2.3e-28 98.1 0.0 5e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 AJW70401.1 - 0.00097 18.6 0.1 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 AJW70401.1 - 0.008 15.5 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Spt4 PF06093.13 AJW70402.1 - 7.6e-13 48.4 0.3 9.6e-13 48.0 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.15 AJW70402.1 - 0.037 13.6 0.7 0.05 13.2 0.7 1.2 1 0 0 1 1 1 0 RecR protein TackOD1 PF18551.1 AJW70402.1 - 0.05 13.3 0.4 0.063 13.0 0.4 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 SHS2_Rpb7-N PF03876.17 AJW70403.1 - 6.5e-17 61.7 0.0 1.5e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 AJW70403.1 - 4.2e-14 52.7 0.0 7.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 AJW70403.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 S1 domain BPL_C PF02237.17 AJW70403.1 - 0.03 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain ParA PF10609.9 AJW70404.1 - 5.1e-100 334.0 0.1 6.5e-100 333.6 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 AJW70404.1 - 3.5e-18 65.5 0.9 1.9e-17 63.2 0.0 2.5 3 0 0 3 3 3 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 AJW70404.1 - 2.8e-13 50.0 0.0 1e-12 48.2 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AJW70404.1 - 2.5e-09 37.3 1.6 9.2e-08 32.2 1.6 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 AJW70404.1 - 3.5e-07 29.8 0.0 5.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AJW70404.1 - 3.6e-07 29.9 0.0 0.00049 19.6 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 AJW70404.1 - 8e-06 25.8 1.1 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 AJW70404.1 - 1.3e-05 24.6 2.2 2.7e-05 23.5 0.5 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase VirC1 PF07015.11 AJW70404.1 - 0.0037 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 AJW70404.1 - 0.0075 15.8 0.0 0.016 14.7 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 AJW70404.1 - 0.012 14.7 0.4 0.018 14.1 0.4 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 AJW70404.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF1610 PF07754.11 AJW70404.1 - 0.035 14.1 0.5 0.066 13.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) AAA_25 PF13481.6 AJW70404.1 - 0.05 13.2 0.5 0.09 12.3 0.5 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AJW70404.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF359 PF04019.12 AJW70405.1 - 8.1e-36 122.4 0.1 1e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF359) SprT-like PF10263.9 AJW70406.1 - 0.0017 18.2 0.2 0.0027 17.5 0.2 1.4 1 1 0 1 1 1 1 SprT-like family DUF45 PF01863.17 AJW70406.1 - 0.0067 16.5 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_M76 PF09768.9 AJW70406.1 - 0.039 13.7 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family H_PPase PF03030.16 AJW70407.1 - 4.8e-224 745.8 52.7 5.6e-224 745.6 52.7 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF2024 PF09630.10 AJW70409.1 - 5.2e-37 125.6 1.4 5.7e-37 125.4 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Cyclophil_like PF04126.13 AJW70410.1 - 9.2e-39 132.0 0.0 1.1e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 AJW70410.1 - 1.4e-07 31.5 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like family Prok-JAB PF14464.6 AJW70411.1 - 1.5e-18 66.7 0.0 1.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 AJW70411.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Toxin-JAB1 PF15659.6 AJW70411.1 - 0.00036 20.8 0.0 0.00046 20.5 0.0 1.3 1 0 0 1 1 1 1 JAB-like toxin 1 DUF3447 PF11929.8 AJW70411.1 - 0.076 13.0 0.8 0.14 12.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Copper-bind PF00127.20 AJW70412.1 - 6.7e-14 52.1 0.1 1.2e-07 32.1 0.0 2.8 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW70412.1 - 1.6e-11 44.2 0.0 0.00024 21.1 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain UbiA PF01040.18 AJW70413.1 - 6.4e-50 169.8 21.0 8.4e-50 169.4 21.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FA_desaturase PF00487.24 AJW70413.1 - 0.33 10.7 0.0 0.33 10.7 0.0 3.5 1 1 3 4 4 4 0 Fatty acid desaturase AAA PF00004.29 AJW70415.1 - 8.3e-89 294.8 0.0 5.3e-48 162.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AJW70415.1 - 6.6e-31 105.9 1.4 7.6e-16 57.7 0.3 2.5 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 AJW70415.1 - 3.2e-25 88.1 0.3 1.4e-24 86.1 0.3 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 AJW70415.1 - 8e-16 58.2 0.2 5.3e-09 36.0 0.0 3.5 2 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AJW70415.1 - 7.1e-12 46.0 0.1 0.0026 18.2 0.0 4.6 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 AJW70415.1 - 9.3e-12 45.4 0.0 9.5e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 AJW70415.1 - 2.6e-11 43.1 0.5 1e-10 41.2 0.2 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 AJW70415.1 - 2.6e-11 43.6 0.0 2.7e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AJW70415.1 - 6.2e-10 39.5 0.8 0.034 14.4 0.0 4.3 2 2 1 4 4 4 2 AAA domain AAA_5 PF07728.14 AJW70415.1 - 1e-09 38.5 0.6 0.00021 21.3 0.0 4.3 4 2 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AJW70415.1 - 4.4e-09 36.6 0.0 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 AJW70415.1 - 6.6e-09 36.0 0.0 0.0012 18.8 0.0 3.8 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AJW70415.1 - 2.3e-08 33.9 0.3 0.31 10.6 0.0 4.3 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 AJW70415.1 - 3.9e-08 33.6 0.0 0.0045 17.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 AJW70415.1 - 4.8e-07 30.4 0.0 0.017 15.7 0.0 2.9 2 1 0 3 3 2 2 ABC transporter IstB_IS21 PF01695.17 AJW70415.1 - 1.6e-06 28.0 0.0 0.025 14.3 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 AJW70415.1 - 1.7e-06 28.6 0.0 0.11 13.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 AJW70415.1 - 3.4e-06 27.1 0.5 0.17 11.8 0.0 3.6 3 2 1 4 4 3 2 Rad17 P-loop domain AAA_28 PF13521.6 AJW70415.1 - 4.8e-06 26.9 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 AJW70415.1 - 8.1e-06 25.3 1.7 0.15 11.3 0.1 3.6 3 1 0 4 4 3 2 KaiC AAA_24 PF13479.6 AJW70415.1 - 8.2e-06 25.7 0.0 0.06 13.1 0.0 3.2 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 AJW70415.1 - 9.1e-06 25.2 1.0 0.018 14.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 AJW70415.1 - 5.2e-05 22.6 0.1 0.17 11.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 AJW70415.1 - 0.00014 21.8 0.5 1.2 9.0 0.0 3.6 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 AJW70415.1 - 0.00032 20.7 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 AJW70415.1 - 0.00049 20.2 0.0 0.85 9.7 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 AJW70415.1 - 0.00069 19.4 0.0 0.7 9.6 0.0 3.6 3 1 0 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 AJW70415.1 - 0.00088 19.1 0.0 0.31 10.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 AJW70415.1 - 0.001 18.4 0.0 1 8.5 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 AJW70415.1 - 0.0012 18.2 0.0 2 7.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 AJW70415.1 - 0.0019 17.8 0.1 0.41 10.1 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region PhoH PF02562.16 AJW70415.1 - 0.0023 17.4 0.7 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein Vps4_C PF09336.10 AJW70415.1 - 0.0032 17.4 0.4 3.2 7.8 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_11 PF13086.6 AJW70415.1 - 0.0041 17.0 0.1 2.4 7.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 AJW70415.1 - 0.006 15.8 0.0 3.8 6.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF815) SRPRB PF09439.10 AJW70415.1 - 0.0072 15.8 0.0 4.1 6.8 0.0 3.4 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 AJW70415.1 - 0.0072 16.8 0.0 4.3 7.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 AJW70415.1 - 0.0094 15.8 0.0 4.2 7.2 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) UFD1 PF03152.14 AJW70415.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Adeno_IVa2 PF02456.15 AJW70415.1 - 0.018 13.9 0.1 5.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.22 AJW70415.1 - 0.019 14.2 0.4 1.6 7.9 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain KAP_NTPase PF07693.14 AJW70415.1 - 0.019 14.2 0.0 4.4 6.4 0.0 3.0 2 1 0 2 2 2 0 KAP family P-loop domain SKI PF01202.22 AJW70415.1 - 0.029 14.5 0.1 3 8.0 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase DAP3 PF10236.9 AJW70415.1 - 0.051 12.7 0.0 6.6 5.8 0.0 3.0 3 1 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 HEPN_SAV_6107 PF18726.1 AJW70415.1 - 0.052 14.1 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 SAV_6107-like HEPN dNK PF01712.19 AJW70415.1 - 0.06 13.2 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Parvo_NS1 PF01057.17 AJW70415.1 - 0.092 11.8 0.1 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_8 PF12780.7 AJW70415.1 - 0.16 11.2 0.0 0.57 9.5 0.0 1.9 2 0 0 2 2 1 0 P-loop containing dynein motor region D4 AAA_19 PF13245.6 AJW70415.1 - 0.25 11.7 1.1 20 5.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain EF1_GNE PF00736.19 AJW70416.1 - 3.2e-18 65.7 0.1 3.5e-18 65.5 0.1 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain FAD_binding_3 PF01494.19 AJW70417.1 - 6.6e-09 35.5 0.6 0.0023 17.2 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 AJW70417.1 - 2.2e-06 27.0 0.0 0.00012 21.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 AJW70417.1 - 1e-05 24.5 0.9 0.0011 17.7 0.1 2.4 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 AJW70417.1 - 3.2e-05 23.7 0.4 0.0059 16.2 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AJW70417.1 - 6.3e-05 22.2 0.0 9.8e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AJW70417.1 - 0.00016 21.0 3.1 0.0014 17.9 2.3 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AJW70417.1 - 0.00019 20.9 0.1 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AJW70417.1 - 0.00023 20.5 0.3 0.00023 20.5 0.3 1.8 2 1 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 AJW70417.1 - 0.00077 19.6 0.2 0.0066 16.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Peptidase_C6 PF00851.18 AJW70417.1 - 0.043 12.7 0.2 0.065 12.1 0.2 1.2 1 0 0 1 1 1 0 Helper component proteinase Amino_oxidase PF01593.24 AJW70417.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase YqzH PF14164.6 AJW70417.1 - 0.16 12.0 0.7 0.68 10.0 0.2 2.2 1 1 1 2 2 2 0 YqzH-like protein PTH2 PF01981.16 AJW70418.1 - 7.5e-40 135.9 0.1 8.3e-40 135.7 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SGL PF08450.12 AJW70419.1 - 6.5e-06 25.9 2.2 1.1 8.7 0.0 4.3 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 AJW70419.1 - 3e-05 24.0 0.7 0.076 13.1 0.0 4.1 3 2 1 4 4 4 2 Domain of unknown function (DUF5074) Reg_prop PF07494.11 AJW70419.1 - 0.055 13.7 10.3 7.6 7.1 0.2 5.1 6 0 0 6 6 6 0 Two component regulator propeller NHL PF01436.21 AJW70419.1 - 0.3 11.2 1.6 7.3 6.8 0.0 3.6 4 0 0 4 4 4 0 NHL repeat AsnC_trans_reg PF01037.21 AJW70420.1 - 1.5e-10 40.9 0.0 1.6e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain ACT_5 PF13710.6 AJW70420.1 - 0.1 12.4 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 ACT domain FtsX PF02687.21 AJW70421.1 - 0.016 15.7 6.6 0.019 15.4 6.6 1.0 1 0 0 1 1 1 0 FtsX-like permease family DUF2530 PF10745.9 AJW70421.1 - 0.045 14.0 2.8 3.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF973 PF06157.11 AJW70421.1 - 0.079 12.0 8.5 0.095 11.7 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2157 PF09925.9 AJW70421.1 - 0.11 12.3 0.9 1.5 8.6 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) PIRT PF15099.6 AJW70421.1 - 0.58 9.7 5.4 0.53 9.9 4.3 1.4 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family DUF202 PF02656.15 AJW70421.1 - 0.84 10.1 2.9 1.4 9.4 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) HRG PF16954.5 AJW70421.1 - 1.6 9.2 7.2 4.6 7.7 0.4 2.3 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF2207 PF09972.9 AJW70421.1 - 2.1 7.0 4.7 2.5 6.8 4.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4083 PF13314.6 AJW70421.1 - 2.4 8.2 7.6 1.2 9.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF3671 PF12420.8 AJW70421.1 - 3.5 7.7 6.3 7 6.8 6.3 1.5 1 1 0 1 1 1 0 Protein of unknown function B12D PF06522.11 AJW70422.1 - 0.2 11.5 0.8 12 5.8 0.2 2.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF2177 PF09945.9 AJW70422.1 - 0.21 11.7 5.6 1.8 8.7 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) DUF1129 PF06570.11 AJW70422.1 - 0.88 9.0 9.5 0.71 9.3 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TMEM208_SND2 PF05620.11 AJW70422.1 - 2.5 7.9 5.6 0.37 10.6 0.3 2.1 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 RDD PF06271.12 AJW70422.1 - 2.8 8.1 12.6 4 7.6 4.4 3.0 2 1 0 2 2 2 0 RDD family HypA PF01155.19 AJW70424.1 - 0.16 12.0 3.5 0.23 11.5 3.5 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Desulfoferrod_N PF06397.12 AJW70424.1 - 0.17 11.5 5.4 1 9.1 0.1 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 AJW70424.1 - 1.5 8.8 6.2 1.1 9.3 2.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Calc_CGRP_IAPP PF00214.19 AJW70426.1 - 0.048 14.0 0.4 0.048 14.0 0.4 1.0 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family ADH_N PF08240.12 AJW70427.1 - 2.5e-28 98.1 0.5 4.4e-28 97.3 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJW70427.1 - 3.3e-16 59.5 0.4 5.1e-16 58.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AJW70427.1 - 4.8e-05 22.8 0.5 6.7e-05 22.3 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AJW70427.1 - 0.00053 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4443 PF14544.6 AJW70427.1 - 0.0082 16.3 0.2 0.024 14.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4443) CoA_binding PF02629.19 AJW70427.1 - 0.09 13.5 6.7 0.19 12.5 3.5 2.9 2 1 1 3 3 3 0 CoA binding domain ADH_zinc_N_2 PF13602.6 AJW70427.1 - 0.13 13.3 0.0 0.24 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GFO_IDH_MocA PF01408.22 AJW70427.1 - 0.21 12.4 0.9 1 10.2 0.1 2.1 1 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Thioredox_DsbH PF03190.15 AJW70429.1 - 2.7e-76 255.1 0.1 4.3e-76 254.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 AJW70429.1 - 9.8e-11 41.7 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 AJW70429.1 - 3.9e-07 29.8 1.1 0.044 13.3 0.1 3.5 3 1 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 AJW70429.1 - 8.2e-05 21.8 0.3 0.085 11.9 0.0 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 AJW70429.1 - 0.0013 18.1 0.0 1.2 8.3 0.0 2.8 2 1 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pec_lyase PF09492.10 AJW70429.1 - 0.0018 17.7 1.2 0.67 9.2 0.1 2.3 2 0 0 2 2 2 2 Pectic acid lyase Glyco_hydro_127 PF07944.12 AJW70429.1 - 0.0055 15.3 0.1 0.28 9.7 0.0 2.6 1 1 2 3 3 3 2 Beta-L-arabinofuranosidase, GH127 LANC_like PF05147.13 AJW70429.1 - 0.02 13.5 3.7 5.9 5.4 0.0 4.3 5 1 0 5 5 5 0 Lanthionine synthetase C-like protein Thioredoxin_2 PF13098.6 AJW70429.1 - 0.023 15.2 0.0 0.064 13.7 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Integrase_Zn PF02022.19 AJW70429.1 - 0.028 14.4 0.0 0.082 12.9 0.0 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain Arcadin_1 PF18653.1 AJW70430.1 - 0.00013 22.0 1.3 0.00018 21.5 1.3 1.2 1 0 0 1 1 1 1 Arcadin 1 Glycoprotein_G PF00802.19 AJW70432.1 - 0.059 12.7 0.8 0.061 12.7 0.8 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DASH_Duo1 PF08651.10 AJW70433.1 - 0.0077 16.0 0.5 0.017 14.8 0.5 1.6 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF5497 PF17601.2 AJW70433.1 - 0.01 16.1 0.0 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5497) Fusion_gly PF00523.18 AJW70433.1 - 0.09 11.0 0.2 0.11 10.8 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Laminin_II PF06009.12 AJW70433.1 - 0.12 12.4 1.1 0.17 11.9 1.1 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF3426 PF11906.8 AJW70434.1 - 9.1e-09 35.6 0.0 9.4e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3426) DUF2393 PF09624.10 AJW70434.1 - 0.00084 19.4 7.6 0.096 12.7 0.2 2.9 2 2 0 2 2 2 2 Protein of unknown function (DUF2393) CTC1_2 PF15491.6 AJW70436.1 - 0.2 10.9 2.2 0.87 8.8 1.0 1.9 1 1 1 2 2 2 0 CST, telomere maintenance, complex subunit CTC1 60KD_IMP PF02096.20 AJW70437.1 - 0.00038 20.4 0.2 0.00061 19.7 0.2 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Vpu PF00558.19 AJW70437.1 - 0.051 13.3 0.5 0.11 12.3 0.5 1.6 1 0 0 1 1 1 0 Vpu protein DUF4298 PF14131.6 AJW70437.1 - 0.054 13.5 4.3 0.29 11.1 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Bac_small_YrzI PF09501.10 AJW70437.1 - 0.11 12.7 0.2 0.11 12.7 0.2 3.0 4 0 0 4 4 4 0 Probable sporulation protein (Bac_small_yrzI) DUF4429 PF14472.6 AJW70437.1 - 0.13 12.8 0.3 1.1 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4429) DUF2681 PF10883.8 AJW70437.1 - 0.67 10.4 4.0 1.8 9.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF465 PF04325.13 AJW70438.1 - 0.11 12.5 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF465) AsnC_trans_reg PF01037.21 AJW70439.1 - 2.7e-08 33.6 0.1 2.8e-08 33.6 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 AJW70439.1 - 0.00026 20.9 0.1 0.00028 20.8 0.1 1.1 1 0 0 1 1 1 1 GYD domain DEAD PF00270.29 AJW70440.1 - 9.5e-51 172.0 0.0 1.5e-49 168.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AJW70440.1 - 5e-32 110.6 0.1 3.3e-30 104.7 0.1 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 AJW70440.1 - 4.2e-05 22.9 0.1 6.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 AJW70440.1 - 0.00046 20.2 0.0 0.00083 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AJW70440.1 - 0.00063 19.5 0.1 0.0016 18.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 AJW70440.1 - 0.0054 16.1 0.3 0.022 14.1 0.0 2.1 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.6 AJW70440.1 - 0.057 13.6 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Helicase_RecD PF05127.14 AJW70440.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Helicase Thioredoxin_4 PF13462.6 AJW70441.1 - 1.8e-40 138.9 0.0 4.1e-40 137.7 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin DSBA PF01323.20 AJW70441.1 - 4e-17 62.6 0.1 3.7e-09 36.6 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJW70441.1 - 2e-10 41.1 0.0 3.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJW70441.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin SurA_N_3 PF13624.6 AJW70441.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain COPI_assoc PF08507.10 AJW70442.1 - 0.0042 17.1 0.5 0.0047 17.0 0.5 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3487 PF11990.8 AJW70442.1 - 0.097 12.6 1.6 0.11 12.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) RELT PF12606.8 AJW70442.1 - 1.7 7.7 6.5 0.24 10.4 2.4 1.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 HRG PF16954.5 AJW70442.1 - 3.2 8.2 8.8 12 6.4 1.3 2.3 1 1 1 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene PvlArgDC PF01862.16 AJW70443.1 - 1.1e-56 191.1 0.0 1.2e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Sh_2 PF17512.2 AJW70444.1 - 0.069 12.9 0.4 0.16 11.7 0.4 1.7 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein YlaC PF10777.9 AJW70445.1 - 1.4 8.7 4.0 0.51 10.2 1.1 1.7 1 1 1 2 2 2 0 Inner membrane protein YlaC Peptidase_M3 PF01432.20 AJW70446.1 - 3.5e-44 151.8 0.5 1.1e-43 150.2 0.5 1.8 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 AJW70446.1 - 0.0009 19.5 5.5 0.001 19.3 0.1 3.6 3 1 0 3 3 3 1 Oligopeptidase F Peptidase_M78 PF06114.13 AJW70446.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 IrrE N-terminal-like domain NPV_P10 PF05531.12 AJW70446.1 - 0.039 14.4 2.0 0.18 12.3 0.2 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF840 PF05801.11 AJW70446.1 - 0.084 13.0 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) Suppressor_APC PF11414.8 AJW70446.1 - 0.13 12.4 0.9 2.5 8.2 0.9 2.4 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CoaE PF01121.20 AJW70447.1 - 0.038 13.7 0.1 0.04 13.6 0.1 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase zf-UBP PF02148.19 AJW70448.1 - 2.1e-11 44.0 8.1 3.7e-11 43.2 8.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 AJW70448.1 - 0.0045 16.7 0.7 0.0072 16.1 0.7 1.4 1 0 0 1 1 1 1 Variant UBP zinc finger Pyrophosphatase PF00719.19 AJW70449.1 - 1.1e-55 187.9 0.3 1.3e-55 187.6 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase S-layer PF07752.11 AJW70449.1 - 0.0072 15.4 0.1 0.015 14.4 0.1 1.6 1 0 0 1 1 1 1 S-layer protein FMN_red PF03358.15 AJW70450.1 - 9.5e-33 113.1 0.0 1.1e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AJW70450.1 - 1.2e-10 41.4 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF5615 PF18480.1 AJW70450.1 - 0.074 12.8 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) DUF5325 PF17259.2 AJW70451.1 - 0.16 11.9 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Nab2 PF11517.8 AJW70453.1 - 0.1 12.9 1.4 0.42 10.9 0.2 2.0 1 1 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Response_reg PF00072.24 AJW70454.1 - 2.9e-21 75.7 0.1 3.3e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain MG2 PF01835.19 AJW70456.1 - 2e-05 24.9 0.0 0.31 11.5 0.0 2.2 2 0 0 2 2 2 2 MG2 domain HTH_52 PF18576.1 AJW70456.1 - 0.12 12.6 0.1 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3244 PF11589.8 AJW70456.1 - 0.25 11.5 6.2 0.3 11.2 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3244) TPR_14 PF13428.6 AJW70457.1 - 0.092 13.6 0.2 0.18 12.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat V-SNARE PF05008.15 AJW70457.1 - 0.31 11.4 2.4 19 5.8 0.1 2.5 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CoA_binding PF02629.19 AJW70458.1 - 2.2e-21 76.3 0.5 4.9e-21 75.2 0.2 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AJW70458.1 - 4.3e-08 33.1 0.1 7.5e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.6 AJW70458.1 - 2.4e-05 24.8 0.0 3.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 AJW70458.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 AJW70458.1 - 0.067 14.0 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ATP-grasp_2 PF08442.10 AJW70459.1 - 3.7e-45 154.0 2.1 6.4e-45 153.2 2.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AJW70459.1 - 3.7e-15 56.1 1.2 5.9e-15 55.4 0.2 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 AJW70459.1 - 1.1e-13 51.2 0.2 3.3e-13 49.6 0.2 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJW70459.1 - 8.3e-06 25.4 0.0 1.3e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AJW70459.1 - 0.011 15.3 0.2 0.025 14.1 0.2 1.7 1 1 0 1 1 1 0 ATP-grasp domain Motilin_ghrelin PF04644.12 AJW70459.1 - 0.14 12.0 0.4 0.33 10.8 0.4 1.6 1 0 0 1 1 1 0 Motilin/ghrelin PH_18 PF18469.1 AJW70460.1 - 0.018 15.0 0.2 0.058 13.4 0.2 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain tRNA_bind PF01588.20 AJW70460.1 - 0.1 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative tRNA binding domain Ferritin PF00210.24 AJW70461.1 - 8.7e-22 77.6 0.0 1.1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain tRNA-synt_1 PF00133.22 AJW70462.1 - 4.5e-139 464.5 1.6 6.7e-139 463.9 1.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJW70462.1 - 4.1e-30 104.8 1.3 9.4e-30 103.6 1.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJW70462.1 - 8.3e-23 80.8 0.0 3.7e-09 35.8 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AJW70462.1 - 5.3e-05 22.7 0.0 0.00086 18.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AJW70462.1 - 0.00011 21.3 0.0 0.0003 19.8 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (K) GARS_A PF01071.19 AJW70463.1 - 1.1e-78 263.5 0.2 1.4e-78 263.1 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AJW70463.1 - 3.2e-33 114.4 0.0 9.1e-33 112.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AJW70463.1 - 1.5e-29 102.1 0.0 3.4e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 AJW70463.1 - 8.7e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AJW70463.1 - 3.8e-06 27.0 0.0 6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 AJW70463.1 - 7.9e-05 22.3 0.9 8.7e-05 22.2 0.1 1.4 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJW70463.1 - 0.00013 21.6 0.1 0.00024 20.7 0.1 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 AJW70463.1 - 0.0019 17.8 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 AJW70463.1 - 0.0027 17.4 0.0 0.0064 16.1 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 AJW70463.1 - 0.026 13.8 0.0 0.12 11.6 0.1 2.1 2 1 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 AJW70463.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 AJW70463.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain 5-FTHF_cyc-lig PF01812.20 AJW70464.1 - 1.9e-39 135.5 0.0 2.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family THF_DHG_CYH_C PF02882.19 AJW70465.1 - 1.2e-60 203.5 0.7 1.7e-60 202.9 0.7 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AJW70465.1 - 2.3e-37 127.8 0.4 4.1e-37 127.0 0.4 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 AJW70465.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 AJW70465.1 - 0.0071 16.8 0.0 0.016 15.7 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF5424 PF17462.2 AJW70465.1 - 0.012 15.5 0.8 0.081 12.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5424) Hydrolase PF00702.26 AJW70465.1 - 0.044 14.1 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sacchrp_dh_NADP PF03435.18 AJW70465.1 - 0.074 13.3 0.2 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ABM PF03992.16 AJW70466.1 - 1.6e-07 31.3 0.0 2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase T3SS_TC PF06511.11 AJW70466.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.0 1 0 0 1 1 1 0 Type III secretion systems tip complex components Cupin_2 PF07883.11 AJW70467.1 - 7.1e-11 41.7 0.1 1.4e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 Cupin domain CENP-C_C PF11699.8 AJW70467.1 - 4.4e-07 30.0 0.1 5.5e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 AJW70467.1 - 3.3e-05 23.8 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Pirin_C PF05726.13 AJW70467.1 - 0.0015 18.9 0.0 0.002 18.5 0.0 1.1 1 0 0 1 1 1 1 Pirin C-terminal cupin domain DMSP_lyase PF16867.5 AJW70467.1 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase ARD PF03079.14 AJW70467.1 - 0.076 13.2 0.9 0.12 12.6 0.9 1.6 1 1 0 1 1 1 0 ARD/ARD' family Formyl_trans_N PF00551.19 AJW70468.1 - 8.7e-47 159.2 0.0 1e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase RMMBL PF07521.12 AJW70469.1 - 0.0051 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Cofac_haem_bdg PF04187.13 AJW70470.1 - 0.11 12.4 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF4147 PF13660.6 AJW70471.1 - 3.3e-68 229.7 0.0 4.4e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AJW70471.1 - 3.3e-29 101.3 0.6 1.6e-28 99.1 0.1 2.1 2 0 0 2 2 2 1 MOFRL family Peptidase_C13 PF01650.18 AJW70471.1 - 0.093 12.2 0.0 0.26 10.7 0.0 1.5 1 1 0 1 1 1 0 Peptidase C13 family Fe-ADH PF00465.19 AJW70472.1 - 5.8e-49 166.8 0.0 8.7e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AJW70472.1 - 5e-16 59.2 0.0 6.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 AJW70472.1 - 8.4e-06 25.1 0.0 0.0038 16.4 0.0 2.1 2 0 0 2 2 2 2 3-dehydroquinate synthase Peripla_BP_6 PF13458.6 AJW70472.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Bac_luciferase PF00296.20 AJW70473.1 - 1.3e-54 185.7 0.0 1.7e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1940 PF09155.10 AJW70474.1 - 0.0072 16.4 0.6 0.0081 16.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1940) FlxA PF14282.6 AJW70475.1 - 0.0053 16.7 10.4 0.0064 16.5 10.4 1.1 1 0 0 1 1 1 1 FlxA-like protein Phage_Gp19 PF09355.10 AJW70475.1 - 0.046 14.1 0.5 0.053 14.0 0.5 1.1 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 HK97-gp10_like PF04883.12 AJW70475.1 - 0.17 12.9 6.2 0.21 12.6 6.2 1.2 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Exonuc_VII_L PF02601.15 AJW70475.1 - 0.23 11.0 5.6 0.23 11.0 5.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 AJW70475.1 - 1.5 8.0 9.5 1.7 7.8 9.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein YtxH PF12732.7 AJW70475.1 - 1.9 9.1 9.4 0.096 13.2 2.0 1.9 1 1 1 2 2 2 0 YtxH-like protein Pyridox_ox_2 PF12900.7 AJW70476.1 - 5.3e-19 68.6 0.0 6.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 AJW70476.1 - 3.2e-09 36.9 0.0 8e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF1059 PF06348.11 AJW70477.1 - 4.1e-10 39.7 0.0 4.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) UvrB_inter PF17757.1 AJW70478.1 - 1.3e-28 99.0 1.4 4.7e-28 97.2 0.8 2.3 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 AJW70478.1 - 3.9e-21 74.6 5.0 1.2e-20 73.1 5.0 1.9 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AJW70478.1 - 8.8e-19 67.9 1.1 3.1e-18 66.1 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UVR PF02151.19 AJW70478.1 - 3.4e-09 36.2 1.1 2.1e-08 33.6 1.1 2.5 1 0 0 1 1 1 1 UvrB/uvrC motif ResIII PF04851.15 AJW70478.1 - 1e-08 35.4 0.3 1.4e-07 31.7 0.1 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJW70478.1 - 1.8e-06 27.9 0.3 0.00029 20.6 0.1 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AJW70478.1 - 0.0014 18.4 0.0 0.018 14.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain Rhomboid_N PF12122.8 AJW70478.1 - 0.017 15.3 0.0 5.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease AAA_19 PF13245.6 AJW70478.1 - 0.17 12.2 3.5 9.7 6.5 0.2 2.8 2 1 0 2 2 2 0 AAA domain Tup_N PF08581.10 AJW70478.1 - 2.6 8.4 17.0 3.6 8.0 0.1 4.0 4 0 0 4 4 4 0 Tup N-terminal UvrA_inter PF17760.1 AJW70479.1 - 4.8e-36 123.2 1.0 1.4e-35 121.7 0.5 2.1 2 0 0 2 2 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AJW70479.1 - 3.7e-33 114.2 0.1 1.7e-30 105.6 0.0 3.4 3 0 0 3 3 3 1 UvrA DNA-binding domain ABC_tran PF00005.27 AJW70479.1 - 2.2e-22 80.1 0.2 0.00026 21.5 0.0 4.6 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 AJW70479.1 - 2.4e-10 40.2 0.2 0.059 12.8 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AJW70479.1 - 4.9e-09 36.4 2.4 0.049 13.4 0.0 4.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AJW70479.1 - 4.4e-08 32.7 0.2 0.0095 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AJW70479.1 - 9.5e-08 32.6 0.0 0.043 14.2 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 AJW70479.1 - 2.8e-06 27.3 0.3 0.062 13.2 0.2 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 AJW70479.1 - 1e-05 25.8 1.1 0.32 11.3 0.0 3.9 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.6 AJW70479.1 - 1.5e-05 25.0 0.0 0.2 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 AJW70479.1 - 1.7e-05 24.2 0.1 0.12 11.5 0.0 3.8 4 0 0 4 4 4 1 NB-ARC domain AAA_33 PF13671.6 AJW70479.1 - 2.8e-05 24.3 0.1 0.22 11.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 AJW70479.1 - 3.3e-05 23.9 0.4 0.3 10.9 0.0 3.5 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AJW70479.1 - 7.8e-05 23.3 6.0 0.00066 20.2 0.1 3.2 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 AJW70479.1 - 0.0001 21.9 0.0 0.16 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AJW70479.1 - 0.0001 22.2 0.1 0.36 10.7 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_15 PF13175.6 AJW70479.1 - 0.00017 21.4 9.3 0.17 11.6 0.1 4.8 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 AJW70479.1 - 0.00018 22.1 0.1 1 9.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 AJW70479.1 - 0.00061 19.4 0.5 0.4 10.3 0.1 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain DnaJ_CXXCXGXG PF00684.19 AJW70479.1 - 0.00085 19.6 11.4 0.018 15.4 0.3 4.1 3 1 1 4 4 4 1 DnaJ central domain DUF2075 PF09848.9 AJW70479.1 - 0.0011 18.4 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AJW70479.1 - 0.0011 18.7 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 AJW70479.1 - 0.0019 17.6 0.1 0.95 8.8 0.0 2.7 2 0 0 2 2 2 1 KaiC NTPase_1 PF03266.15 AJW70479.1 - 0.002 18.1 0.8 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 NTPase NACHT PF05729.12 AJW70479.1 - 0.0021 18.0 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 AJW70479.1 - 0.0033 16.9 0.1 0.91 9.0 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region MeaB PF03308.16 AJW70479.1 - 0.0039 16.2 0.0 0.46 9.4 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 AJW70479.1 - 0.0058 16.7 0.4 0.9 9.6 0.1 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 AJW70479.1 - 0.0059 15.7 0.3 2.6 7.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.22 AJW70479.1 - 0.016 15.6 0.2 4.1 7.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase PRK PF00485.18 AJW70479.1 - 0.025 14.3 0.0 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 AJW70479.1 - 0.029 14.1 0.1 11 5.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 AJW70479.1 - 0.045 14.0 0.1 9.5 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RACo_linker PF17650.1 AJW70479.1 - 0.051 13.4 0.1 6 6.8 0.0 3.2 3 0 0 3 3 3 0 RACo linker region AAA_24 PF13479.6 AJW70479.1 - 0.056 13.1 4.6 14 5.4 0.1 4.1 4 0 0 4 4 4 0 AAA domain MobB PF03205.14 AJW70479.1 - 0.073 13.0 0.0 9.1 6.2 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 AJW70479.1 - 0.078 12.2 0.0 6.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 AJW70479.1 - 0.18 11.5 0.6 5.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein zinc_ribbon_2 PF13240.6 AJW70479.1 - 0.83 9.5 8.4 1.8 8.4 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJW70479.1 - 9.3 5.8 8.8 0.94 9.0 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain UvrC_HhH_N PF08459.11 AJW70480.1 - 4e-47 160.0 0.0 1.1e-46 158.5 0.0 1.8 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 AJW70480.1 - 5e-11 42.7 1.6 5e-11 42.7 1.6 2.3 3 0 0 3 3 3 1 GIY-YIG catalytic domain UVR PF02151.19 AJW70480.1 - 7.2e-09 35.1 0.4 2.3e-08 33.5 0.4 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif LIN52 PF10044.9 AJW70480.1 - 0.19 12.5 1.6 2.3 9.0 0.7 2.7 3 0 0 3 3 3 0 Retinal tissue protein Copper-bind PF00127.20 AJW70481.1 - 1.4e-08 35.0 1.3 2.9e-08 34.1 0.0 2.1 2 2 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW70481.1 - 0.00089 19.3 0.0 0.0045 17.1 0.0 2.1 2 1 0 2 2 2 1 Cupredoxin-like domain Peptidase_S49_N PF08496.10 AJW70481.1 - 0.082 13.0 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PA26 PF04636.13 AJW70481.1 - 0.22 10.4 0.1 0.29 10.0 0.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4678 PF15727.5 AJW70481.1 - 0.4 9.9 4.8 0.55 9.5 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) O-antigen_lig PF13425.6 AJW70484.1 - 0.43 9.3 3.5 0.47 9.2 3.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pyr_redox_2 PF07992.14 AJW70485.1 - 3.8e-43 147.8 0.0 4.7e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJW70485.1 - 5.3e-09 36.5 1.0 3.1e-06 27.7 0.6 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 AJW70485.1 - 0.047 14.0 0.4 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 AJW70485.1 - 0.07 13.1 0.2 7.7 6.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 AJW70485.1 - 0.076 12.2 0.0 6.7 5.7 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) SepSecS PF05889.13 AJW70486.1 - 0.02 13.6 1.0 0.03 13.0 1.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Phasin PF05597.11 AJW70486.1 - 0.22 11.5 0.5 0.88 9.6 0.1 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Usp PF00582.26 AJW70487.1 - 1.9e-20 73.8 0.0 2.3e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family CW_7 PF08230.11 AJW70487.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 CW_7 repeat Response_reg PF00072.24 AJW70488.1 - 7.9e-13 48.6 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain DUF1487 PF07368.11 AJW70488.1 - 0.011 15.2 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) PPP1R35_C PF15503.6 AJW70488.1 - 0.083 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Response_reg PF00072.24 AJW70489.1 - 2.2e-23 82.5 0.4 2.5e-23 82.4 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF948 PF06103.11 AJW70489.1 - 0.1 12.9 0.3 0.15 12.3 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HATPase_c PF02518.26 AJW70490.1 - 1.2e-19 70.9 1.6 1.4e-19 70.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW70490.1 - 4e-07 30.0 0.9 1.6e-06 28.0 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Wzy_C PF04932.15 AJW70490.1 - 0.0092 15.6 0.8 0.041 13.5 0.1 2.1 2 0 0 2 2 2 1 O-Antigen ligase Gag_p10 PF02337.17 AJW70490.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral GAG p10 protein LapA_dom PF06305.11 AJW70490.1 - 0.042 13.7 0.2 0.042 13.7 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3175 PF11373.8 AJW70490.1 - 0.053 13.7 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) Sec20 PF03908.13 AJW70490.1 - 0.24 11.3 2.8 0.47 10.4 0.3 2.7 2 0 0 2 2 2 0 Sec20 DUF948 PF06103.11 AJW70490.1 - 0.41 10.9 3.1 0.8 10.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4559 PF15112.6 AJW70490.1 - 0.54 9.9 7.1 0.15 11.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) TMF_DNA_bd PF12329.8 AJW70490.1 - 2.9 8.0 14.2 0.14 12.2 7.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Response_reg PF00072.24 AJW70491.1 - 7.5e-15 55.1 0.2 8.8e-15 54.9 0.2 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Prenyltransf PF01255.19 AJW70491.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 1 1 2 2 2 0 Putative undecaprenyl diphosphate synthase DUF5441 PF17513.2 AJW70491.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5441) NHL PF01436.21 AJW70493.1 - 6e-12 45.0 3.6 0.22 11.6 0.0 7.5 7 2 2 9 9 9 4 NHL repeat Lactonase PF10282.9 AJW70493.1 - 2.1e-11 43.7 3.2 0.03 13.6 0.2 5.0 1 1 4 5 5 5 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AJW70493.1 - 1.7e-06 26.8 4.6 0.00038 19.1 0.8 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain Glu_cyclase_2 PF05096.12 AJW70493.1 - 3.8e-06 26.5 1.5 3.8e-05 23.2 0.4 2.6 1 1 2 3 3 3 2 Glutamine cyclotransferase Arylesterase PF01731.20 AJW70493.1 - 9.3e-06 25.8 14.4 1.9 8.8 0.2 5.4 4 1 1 5 5 5 3 Arylesterase SBBP PF06739.11 AJW70493.1 - 0.019 14.9 6.4 2.2 8.3 0.1 4.8 4 0 0 4 4 4 0 Beta-propeller repeat DUF5074 PF16819.5 AJW70493.1 - 0.045 13.8 7.0 0.17 11.9 0.0 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF5074) HPS3_N PF14761.6 AJW70493.1 - 0.062 12.8 1.1 5.5 6.5 0.2 2.3 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 BBS1 PF14779.6 AJW70493.1 - 0.088 12.2 1.6 3.5 7.0 0.0 3.1 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 1 DUF5128 PF17170.4 AJW70493.1 - 0.33 10.1 10.2 0.51 9.4 3.1 2.7 1 1 1 2 2 2 0 6-bladed beta-propeller Response_reg PF00072.24 AJW70494.1 - 1.2e-27 96.3 0.6 1.4e-27 96.1 0.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain GATase1_like PF07090.11 AJW70494.1 - 0.15 11.5 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Putative glutamine amidotransferase SAP PF02037.27 AJW70494.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 SAP domain CheR PF01739.18 AJW70495.1 - 1.2e-51 175.0 0.4 1.9e-51 174.4 0.4 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AJW70495.1 - 5.7e-08 32.4 0.1 1.2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_31 PF13847.6 AJW70495.1 - 0.00037 20.3 0.4 0.0024 17.7 0.2 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW70495.1 - 0.0012 19.6 0.1 0.009 16.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain GnsAB_toxin PF08178.11 AJW70495.1 - 0.0023 17.8 2.1 0.018 14.9 0.9 2.9 3 0 0 3 3 3 1 GnsA/GnsB toxin of bacterial toxin-antitoxin system Methyltransf_25 PF13649.6 AJW70495.1 - 0.004 17.8 0.0 0.19 12.4 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain ComR_TPR PF18710.1 AJW70495.1 - 0.0044 16.6 5.9 0.45 10.0 0.2 2.4 2 0 0 2 2 2 2 ComR tetratricopeptide Methyltransf_11 PF08241.12 AJW70495.1 - 0.014 16.0 0.0 0.13 13.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF4287 PF14117.6 AJW70495.1 - 0.036 14.2 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) CheC PF04509.12 AJW70496.1 - 4e-12 45.8 1.3 6.5e-11 41.9 0.0 2.7 3 0 0 3 3 3 1 CheC-like family CheX PF13690.6 AJW70496.1 - 4.5e-07 30.0 0.3 2.1e-06 27.8 0.1 2.1 1 1 1 2 2 2 1 Chemotaxis phosphatase CheX CheW PF01584.19 AJW70497.1 - 2.1e-23 82.5 0.2 4.1e-23 81.6 0.2 1.5 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.26 AJW70497.1 - 1.1e-15 58.1 1.6 1.1e-15 58.1 1.6 2.0 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 AJW70497.1 - 6.7e-13 48.7 0.1 2.7e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Hpt domain H-kinase_dim PF02895.14 AJW70497.1 - 1.8e-10 41.0 3.8 6.3e-10 39.3 3.8 2.0 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c_3 PF13589.6 AJW70497.1 - 0.0017 18.2 0.6 0.0017 18.2 0.6 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW70497.1 - 0.01 15.8 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Alpha-E PF04168.12 AJW70497.1 - 0.057 13.2 1.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. DUF2730 PF10805.8 AJW70497.1 - 0.21 11.7 4.2 1.4 9.1 0.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Arch_flagellin PF01917.16 AJW70497.1 - 0.33 11.1 4.5 0.24 11.6 1.4 2.4 2 1 0 2 2 2 0 Archaebacterial flagellin ALMT PF11744.8 AJW70497.1 - 0.41 9.4 8.3 0.18 10.6 2.3 2.2 1 1 1 2 2 2 0 Aluminium activated malate transporter F_actin_bind PF08919.10 AJW70497.1 - 0.63 10.2 4.4 1.9 8.6 2.5 2.4 2 0 0 2 2 2 0 F-actin binding CsgF PF10614.9 AJW70497.1 - 0.94 9.7 4.5 2.9 8.1 0.1 2.4 1 1 1 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein GramPos_pilinD3 PF16570.5 AJW70497.1 - 1.3 9.8 5.5 0.41 11.4 2.2 1.8 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain CheB_methylest PF01339.17 AJW70498.1 - 5.2e-57 192.3 0.2 1.2e-56 191.1 0.1 1.6 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AJW70498.1 - 5.5e-20 71.6 0.4 1.5e-19 70.2 0.2 1.8 2 0 0 2 2 2 1 Response regulator receiver domain LLGL PF08366.13 AJW70498.1 - 0.087 13.2 0.2 8 6.9 0.0 2.5 2 1 0 2 2 2 0 LLGL2 CheW PF01584.19 AJW70500.1 - 2.6e-32 111.3 0.1 3.9e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 CheW-like domain Aha1_N PF09229.11 AJW70500.1 - 0.0003 21.0 3.2 0.0016 18.6 3.2 1.9 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF1292 PF06949.11 AJW70500.1 - 0.14 13.1 2.9 0.24 12.4 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) MCPsignal PF00015.21 AJW70501.1 - 4.7e-38 130.7 44.2 4.4e-37 127.5 22.2 3.8 1 1 3 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.7 AJW70501.1 - 3.7e-11 43.2 0.2 1.9e-10 40.9 0.1 2.3 1 1 1 2 2 2 1 PAS domain PAS PF00989.25 AJW70501.1 - 9.5e-09 35.3 0.3 8.7e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AJW70501.1 - 3.5e-06 27.2 0.1 7.1e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AJW70501.1 - 4e-05 23.8 0.0 0.00022 21.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold Topoisom_I PF01028.20 AJW70501.1 - 0.00016 21.0 3.0 0.00052 19.3 3.0 1.9 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core SLED PF12140.8 AJW70501.1 - 0.4 11.2 5.1 2.8 8.5 0.9 3.3 2 1 1 3 3 3 0 SLED domain Cor1 PF04803.12 AJW70501.1 - 0.67 10.2 7.3 0.93 9.7 2.2 3.3 2 2 1 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1759 PF03564.15 AJW70501.1 - 1 9.3 6.0 0.66 9.9 0.3 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1759) Fib_alpha PF08702.10 AJW70501.1 - 1.3 9.2 22.9 3.2 7.9 8.0 3.7 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4904 PF16247.5 AJW70501.1 - 1.7 8.4 5.2 1.1 9.0 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4904) Nup88 PF10168.9 AJW70501.1 - 2.4 5.8 17.1 0.13 10.1 1.5 2.1 2 0 0 2 2 2 0 Nuclear pore component T7SS_ESX_EspC PF10824.8 AJW70501.1 - 3.6 8.1 17.2 1.9 9.0 0.1 4.0 3 1 1 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm eIF3_N PF09440.10 AJW70501.1 - 4.3 7.8 17.6 4.2 7.8 0.7 4.1 1 1 3 4 4 4 0 eIF3 subunit 6 N terminal domain APG17 PF04108.12 AJW70501.1 - 6.4 5.8 17.7 3.7 6.6 2.4 2.8 1 1 0 2 2 2 0 Autophagy protein Apg17 dCache_1 PF02743.18 AJW70501.1 - 8.1 6.1 14.2 0.23 11.2 1.0 3.7 1 1 0 2 2 2 0 Cache domain DUF948 PF06103.11 AJW70501.1 - 8.6 6.7 29.1 48 4.3 2.9 5.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) T2SSF PF00482.23 AJW70502.1 - 0.00038 20.4 0.2 0.033 14.1 0.1 3.9 3 1 1 4 4 4 2 Type II secretion system (T2SS), protein F DUF3271 PF11675.8 AJW70502.1 - 0.015 14.6 1.1 0.033 13.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3271) DUF1419 PF07215.11 AJW70502.1 - 0.26 11.4 2.2 15 5.8 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1419) T2SSE PF00437.20 AJW70503.1 - 9.5e-43 146.2 0.0 1.3e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein SoxE PF06525.11 AJW70503.1 - 0.065 12.7 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain ATPase PF06745.13 AJW70504.1 - 5e-19 68.6 0.7 5.9e-19 68.3 0.7 1.0 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.11 AJW70504.1 - 1.9e-05 24.0 0.8 0.049 12.8 0.0 2.1 1 1 0 2 2 2 2 PAXNEB protein AAA_25 PF13481.6 AJW70504.1 - 0.00019 21.1 0.1 0.0044 16.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.11 AJW70504.1 - 0.00019 20.8 0.1 0.00044 19.6 0.1 1.5 1 0 0 1 1 1 1 Rad51 DUF835 PF05763.12 AJW70504.1 - 0.00055 19.7 1.7 0.0012 18.6 1.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF835) Elong_Iki1 PF10483.9 AJW70504.1 - 0.0093 15.5 0.6 0.011 15.3 0.6 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 AAA_14 PF13173.6 AJW70504.1 - 0.01 15.9 1.4 0.14 12.2 1.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AJW70504.1 - 0.017 15.5 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 AJW70504.1 - 0.026 15.1 0.3 0.33 11.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AJW70504.1 - 0.03 13.6 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 AJW70504.1 - 0.053 13.5 0.8 0.083 12.9 0.8 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AJW70504.1 - 0.056 13.4 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 AJW70504.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_flagellin PF01917.16 AJW70506.1 - 9.6e-11 42.1 3.2 1.2e-10 41.8 3.2 1.0 1 0 0 1 1 1 1 Archaebacterial flagellin LPP PF04728.13 AJW70507.1 - 0.027 14.8 0.2 0.089 13.2 0.2 2.0 1 0 0 1 1 1 0 Lipoprotein leucine-zipper ASFV_J13L PF05568.11 AJW70507.1 - 0.72 9.6 8.4 7.4 6.3 3.2 2.5 1 1 1 2 2 2 0 African swine fever virus J13L protein DUF1664 PF07889.12 AJW70507.1 - 0.96 9.5 4.4 0.34 11.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) VCX_VCY PF15231.6 AJW70507.1 - 2 9.1 29.2 2.1 9.1 9.4 2.8 2 1 1 3 3 3 0 Variable charge X/Y family Arch_flagellin PF01917.16 AJW70508.1 - 1.4e-24 87.1 8.3 2.3e-24 86.5 8.3 1.3 1 0 0 1 1 1 1 Archaebacterial flagellin DUF5325 PF17259.2 AJW70508.1 - 0.1 12.5 2.6 0.21 11.5 2.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Pilin_N PF07790.11 AJW70508.1 - 4 8.4 7.8 11 7.0 6.6 2.3 2 1 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Arch_flagellin PF01917.16 AJW70509.1 - 1e-18 68.0 3.3 1.6e-18 67.4 3.3 1.3 1 1 0 1 1 1 1 Archaebacterial flagellin Arch_flagellin PF01917.16 AJW70510.1 - 4.3e-25 88.8 5.8 5.4e-25 88.5 5.8 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin DUF5325 PF17259.2 AJW70510.1 - 0.11 12.4 2.8 0.25 11.3 2.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Arch_flagellin PF01917.16 AJW70511.1 - 1.8e-21 77.0 7.9 2.3e-21 76.7 7.9 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin DUF5325 PF17259.2 AJW70511.1 - 0.1 12.5 3.3 0.25 11.3 2.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Copper-bind PF00127.20 AJW70512.1 - 8e-05 23.0 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AJW70512.1 - 0.05 13.7 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain Arch_flagellin PF01917.16 AJW70513.1 - 4.6e-22 78.9 5.2 5.7e-22 78.6 5.2 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin DUF5325 PF17259.2 AJW70513.1 - 0.12 12.3 2.3 0.26 11.2 2.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) TrmB PF01978.19 AJW70514.1 - 1.2e-15 57.2 0.0 5e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 AJW70514.1 - 0.00011 21.5 0.1 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_5 PF01022.20 AJW70514.1 - 0.0048 16.7 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Bacillus_HBL PF05791.11 AJW70514.1 - 0.0087 15.9 0.3 0.015 15.1 0.3 1.4 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) HTH_11 PF08279.12 AJW70514.1 - 0.0088 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 HTH domain Anticodon_1 PF08264.13 AJW70514.1 - 0.032 14.2 0.2 0.098 12.6 0.0 1.8 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA HTH_24 PF13412.6 AJW70514.1 - 0.033 13.8 0.1 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Ribosomal_S25 PF03297.15 AJW70514.1 - 0.037 14.2 0.2 0.12 12.6 0.0 1.9 2 1 0 2 2 2 0 S25 ribosomal protein HTH_Crp_2 PF13545.6 AJW70514.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TPR_2 PF07719.17 AJW70515.1 - 1.2e-52 171.8 16.8 1.1e-05 25.2 0.0 14.1 15 0 0 15 15 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 AJW70515.1 - 8.3e-47 157.6 8.6 1.6e-09 38.1 0.1 8.6 4 2 4 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 AJW70515.1 - 3.9e-46 153.1 33.9 1.5e-06 27.7 1.3 13.7 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_16 PF13432.6 AJW70515.1 - 3.4e-39 133.2 0.0 6.5e-07 29.9 0.0 9.0 5 1 2 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 AJW70515.1 - 1.5e-37 124.7 30.1 3.7e-05 23.6 0.0 13.0 12 1 1 13 13 13 8 Tetratricopeptide repeat ANAPC3 PF12895.7 AJW70515.1 - 5.4e-36 122.7 18.9 1.1e-08 35.2 0.1 7.8 2 2 8 10 10 10 9 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AJW70515.1 - 1.5e-34 115.7 0.0 9.8e-05 22.9 0.0 12.5 3 3 11 14 14 14 7 Tetratricopeptide repeat TPR_6 PF13174.6 AJW70515.1 - 2.5e-30 103.1 5.4 0.048 14.3 0.0 13.0 15 0 0 15 15 13 5 Tetratricopeptide repeat TPR_7 PF13176.6 AJW70515.1 - 1.1e-27 94.0 8.1 0.011 15.7 0.0 11.3 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_17 PF13431.6 AJW70515.1 - 1.2e-26 91.2 23.4 0.0044 17.3 0.0 11.7 13 0 0 13 13 12 8 Tetratricopeptide repeat TPR_12 PF13424.6 AJW70515.1 - 1.3e-26 92.6 8.9 0.00032 20.9 0.0 9.5 7 3 2 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 AJW70515.1 - 2e-26 91.4 20.2 9.9e-08 31.5 0.3 9.9 7 3 4 11 11 10 6 TPR repeat TPR_9 PF13371.6 AJW70515.1 - 8.1e-17 61.2 0.0 0.018 15.2 0.0 7.1 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_20 PF14561.6 AJW70515.1 - 1.7e-14 53.9 3.3 0.036 14.4 0.0 8.2 3 2 5 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 AJW70515.1 - 1.4e-09 37.5 5.7 3.9 7.5 0.0 9.5 9 1 0 10 10 9 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 AJW70515.1 - 4.6e-08 33.1 21.2 0.057 13.4 1.0 5.7 2 2 3 5 5 5 4 Putative TPR-like repeat Fis1_TPR_C PF14853.6 AJW70515.1 - 6.3e-08 32.6 13.7 1.5 9.0 0.0 9.9 5 3 7 12 12 11 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 AJW70515.1 - 8.8e-07 28.2 18.8 1.1 8.1 0.0 6.4 1 1 4 7 7 7 3 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 AJW70515.1 - 9.7e-06 24.5 0.0 0.49 9.1 0.0 3.4 3 1 0 3 3 3 2 Protein kinase G tetratricopeptide repeat Rapsyn_N PF10579.9 AJW70515.1 - 1.1e-05 25.4 1.6 1.9 8.7 0.0 5.4 4 2 2 6 6 6 2 Rapsyn N-terminal myristoylation and linker region HrpB1_HrpK PF09613.10 AJW70515.1 - 4e-05 23.3 0.0 5.2 6.7 0.0 5.2 3 3 2 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 AJW70515.1 - 6.4e-05 22.5 12.6 0.016 14.6 0.8 4.3 1 1 3 4 4 4 2 Coatomer epsilon subunit TPR_21 PF09976.9 AJW70515.1 - 0.00012 21.9 6.9 1.8 8.2 0.1 4.9 2 1 3 5 5 5 1 Tetratricopeptide repeat-like domain YfiO PF13525.6 AJW70515.1 - 0.00022 21.0 7.4 0.014 15.2 0.1 4.1 2 1 2 4 4 4 1 Outer membrane lipoprotein Alkyl_sulf_dimr PF14863.6 AJW70515.1 - 0.00051 20.5 4.8 0.58 10.6 0.1 4.7 3 3 3 6 6 6 1 Alkyl sulfatase dimerisation PPR PF01535.20 AJW70515.1 - 0.0023 18.1 3.8 32 5.1 0.0 7.2 9 0 0 9 9 8 0 PPR repeat Orthopox_F14 PF06076.12 AJW70515.1 - 0.015 15.6 0.3 0.05 13.9 0.3 1.9 1 0 0 1 1 1 0 Orthopoxvirus F14 protein DUF5625 PF18539.1 AJW70515.1 - 0.15 12.4 3.6 0.14 12.4 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5625) DUF5099 PF17025.5 AJW70515.1 - 1.7 9.1 9.6 0.19 12.2 1.2 3.6 3 2 1 4 4 3 0 Domain of unknown function (DUF5099) MIT PF04212.18 AJW70515.1 - 3.1 8.0 17.9 13 6.0 0.1 8.3 9 1 1 10 10 10 0 MIT (microtubule interacting and transport) domain TPPII_N PF12583.8 AJW70515.1 - 7.6 7.1 5.9 51 4.4 0.1 3.1 2 1 0 3 3 3 0 Tripeptidyl peptidase II N terminal Big_1 PF02369.16 AJW70516.1 - 2.7e-06 27.3 0.0 2.7e-06 27.3 0.0 4.9 6 1 0 6 6 6 1 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 AJW70516.1 - 0.0031 17.8 8.0 1.2 9.5 0.1 4.6 5 0 0 5 5 5 3 Invasin, domain 3 Acetone_carb_G PF08882.11 AJW70517.1 - 0.025 14.7 2.1 3.4 7.9 0.2 2.6 2 1 1 3 3 3 0 Acetone carboxylase gamma subunit Peptidase_M10 PF00413.24 AJW70518.1 - 2.5e-09 37.2 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 AJW70518.1 - 0.0002 21.1 0.1 0.00029 20.5 0.1 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 AJW70518.1 - 0.003 16.5 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 AJW70518.1 - 0.0045 17.5 0.0 0.0074 16.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 AJW70518.1 - 0.069 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 AJW70518.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Response_reg PF00072.24 AJW70519.1 - 1.9e-13 50.5 0.0 3.4e-13 49.7 0.0 1.4 1 1 0 1 1 1 1 Response regulator receiver domain ThiF PF00899.21 AJW70520.1 - 0.027 13.8 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 ThiF family DUF3289 PF11692.8 AJW70521.1 - 0.041 13.5 0.0 0.041 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) HTH_Tnp_Tc3_1 PF11427.8 AJW70521.1 - 0.08 12.8 0.4 0.15 11.9 0.2 1.7 1 1 1 2 2 2 0 Tc3 transposase DUF1059 PF06348.11 AJW70522.1 - 1.6e-08 34.7 0.0 1.6e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) HATPase_c PF02518.26 AJW70524.1 - 1.4e-16 60.9 0.0 4.3e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW70524.1 - 8.8e-08 32.1 2.8 1e-07 31.9 0.1 2.4 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW70524.1 - 2.5e-07 30.5 1.1 5.7e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 GHKL domain DUF1574 PF07611.11 AJW70524.1 - 0.0016 17.9 7.8 0.0022 17.4 7.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1574) HATPase_c_2 PF13581.6 AJW70524.1 - 0.0068 16.4 0.1 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AJW70524.1 - 0.039 13.8 1.0 0.082 12.7 0.0 2.0 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DIT1_PvcA PF05141.12 AJW70524.1 - 0.1 12.1 9.5 0.19 11.2 9.5 1.4 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein EIAV_Rev PF11129.8 AJW70524.1 - 0.18 12.0 0.3 0.33 11.2 0.3 1.4 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus DUF5401 PF17380.2 AJW70524.1 - 0.24 9.4 13.5 0.28 9.2 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4250 PF14056.6 AJW70524.1 - 0.37 10.8 3.6 0.25 11.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) CCD48 PF15799.5 AJW70524.1 - 3.6 5.8 7.1 4.6 5.4 6.4 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF4962 PF16332.5 AJW70524.1 - 8.7 4.7 9.2 14 4.1 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Response_reg PF00072.24 AJW70525.1 - 4.8e-23 81.5 0.8 5.9e-23 81.2 0.8 1.1 1 0 0 1 1 1 1 Response regulator receiver domain SpoU_sub_bind PF08032.12 AJW70525.1 - 0.076 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Titin_Ig-rpts PF06582.12 AJW70526.1 - 0.053 13.5 0.4 0.34 10.9 0.4 2.5 1 0 0 1 1 1 0 Titin repeat Cuticle_1 PF08140.11 AJW70526.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Pneumo_M2 PF07380.11 AJW70526.1 - 9.4 6.6 10.1 15 6.0 0.5 4.8 3 2 2 5 5 5 0 Pneumovirus M2 protein DUF4562 PF15123.6 AJW70528.1 - 0.16 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) Peptidase_S24 PF00717.23 AJW70530.1 - 1.4e-08 34.6 1.1 2.5e-08 33.8 1.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Tetraspanin PF00335.20 AJW70530.1 - 0.033 13.9 1.4 0.041 13.6 0.3 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF4059 PF13268.6 AJW70530.1 - 0.074 13.5 0.4 0.074 13.5 0.4 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF4059) Cation_ATPase_C PF00689.21 AJW70530.1 - 0.085 12.6 5.0 0.17 11.6 5.0 1.5 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus TctB PF07331.11 AJW70530.1 - 0.11 12.8 5.8 2.6 8.3 4.9 2.9 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family 7TM-7TMR_HD PF07698.11 AJW70530.1 - 0.11 12.2 11.2 0.068 12.9 1.8 2.5 2 1 1 3 3 3 0 7TM receptor with intracellular HD hydrolase DUF1980 PF09323.10 AJW70530.1 - 0.79 9.6 5.7 0.32 10.9 2.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) DHHC PF01529.20 AJW70530.1 - 7.5 6.7 9.1 8.8 6.4 0.3 2.7 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF4884 PF16225.5 AJW70531.1 - 0.16 12.1 1.4 0.3 11.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4884) HATPase_c PF02518.26 AJW70532.1 - 3.1e-18 66.3 0.5 6.1e-18 65.4 0.5 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AJW70532.1 - 3.1e-10 39.9 0.4 3.1e-10 39.9 0.4 2.0 2 0 0 2 2 2 1 GHKL domain HisKA PF00512.25 AJW70532.1 - 6.2e-10 39.0 0.8 7.8e-09 35.5 0.0 2.8 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AJW70532.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AJW70532.1 - 0.019 14.8 0.1 0.054 13.3 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PIN_8 PF18476.1 AJW70532.1 - 0.72 9.7 13.9 0.46 10.3 6.4 2.5 1 1 1 2 2 2 0 PIN like domain PhoU PF01895.19 AJW70532.1 - 0.93 10.0 13.1 7.7 7.1 3.4 3.8 3 1 0 3 3 3 0 PhoU domain Citrate_synt PF00285.21 AJW70534.1 - 2e-133 445.0 0.1 2.2e-133 444.8 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF5446 PF17522.2 AJW70534.1 - 0.013 15.7 1.1 0.038 14.2 1.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF4924 PF16271.5 AJW70534.1 - 0.018 15.1 1.1 0.072 13.1 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4924) UPF0146 PF03686.13 AJW70534.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DHHA1 PF02272.19 AJW70536.1 - 6.7e-16 59.0 0.7 6.7e-16 59.0 0.7 2.3 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.20 AJW70536.1 - 5.4e-05 23.4 1.7 0.00013 22.2 1.7 1.6 1 0 0 1 1 1 1 DHH family DUF1829 PF08862.10 AJW70536.1 - 0.45 11.0 3.5 1.1 9.8 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF1829 YjgF_endoribonc PF14588.6 AJW70537.1 - 2.4e-32 112.1 0.0 2.6e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 AJW70537.1 - 5.9e-22 77.9 0.0 7.3e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Response_reg PF00072.24 AJW70538.1 - 3.4e-22 78.7 0.4 3.7e-22 78.6 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TrmB PF01978.19 AJW70539.1 - 2.1e-16 59.5 1.3 2.4e-15 56.2 0.2 2.5 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 AJW70539.1 - 0.0073 15.5 0.2 0.014 14.6 0.2 1.4 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB Agarase_CBM PF17992.1 AJW70540.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Agarase CBM like domain DUF948 PF06103.11 AJW70541.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Cytochrom_B562 PF07361.11 AJW70541.1 - 0.021 15.4 0.9 0.076 13.7 0.1 2.1 2 1 0 2 2 2 0 Cytochrome b562 MukB PF04310.12 AJW70541.1 - 0.054 13.3 0.4 0.068 13.0 0.4 1.2 1 0 0 1 1 1 0 MukB N-terminal DcpS_C PF11969.8 AJW70541.1 - 0.077 13.5 1.4 0.12 12.8 0.9 1.7 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding DUF1664 PF07889.12 AJW70541.1 - 0.83 9.7 5.6 0.58 10.2 1.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) AAA PF00004.29 AJW70542.1 - 3e-38 131.2 0.0 1.1e-37 129.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 AJW70542.1 - 2.1e-09 37.3 0.2 4.4e-09 36.3 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.14 AJW70542.1 - 1.9e-07 31.4 0.0 4.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 AJW70542.1 - 4.2e-07 29.9 0.2 9.2e-06 25.6 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 AJW70542.1 - 6.3e-06 26.5 0.0 0.00049 20.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 AJW70542.1 - 6.5e-06 25.8 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 AJW70542.1 - 1.3e-05 25.7 0.0 0.0065 16.9 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 AJW70542.1 - 9.5e-05 22.2 0.0 0.00027 20.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 AJW70542.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AJW70542.1 - 0.00028 21.1 0.1 0.034 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AJW70542.1 - 0.00085 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 AJW70542.1 - 0.0021 18.1 0.1 0.018 15.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AJW70542.1 - 0.0037 17.2 0.0 1.6 8.6 0.0 2.5 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 AJW70542.1 - 0.005 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 AJW70542.1 - 0.0095 15.5 0.0 0.031 13.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 AJW70542.1 - 0.01 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 AJW70542.1 - 0.013 14.8 0.1 0.066 12.5 0.0 2.2 2 1 0 2 2 1 0 Zeta toxin IstB_IS21 PF01695.17 AJW70542.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 AJW70542.1 - 0.023 14.7 0.1 0.067 13.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 AJW70542.1 - 0.031 14.1 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AJW70542.1 - 0.04 13.3 0.1 1.9 7.8 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 AJW70542.1 - 0.092 13.1 0.1 0.4 11.1 0.0 2.2 3 0 0 3 3 1 0 RNA helicase KAP_NTPase PF07693.14 AJW70542.1 - 0.093 12.0 0.0 1.5 8.0 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Parvo_NS1 PF01057.17 AJW70542.1 - 0.13 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 AJW70542.1 - 0.15 11.9 0.0 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 AJW70542.1 - 0.16 12.4 0.4 3.3 8.2 0.0 2.8 3 1 0 3 3 3 0 ABC transporter AAA_30 PF13604.6 AJW70542.1 - 0.17 11.6 0.1 0.52 10.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 AJW70542.1 - 0.17 11.3 0.3 0.36 10.2 0.3 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 AJW70542.1 - 0.19 12.1 0.4 3.5 8.0 0.3 2.7 2 1 1 3 3 3 0 AAA domain GATase PF00117.28 AJW70543.1 - 4.8e-45 153.7 0.1 6.6e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 AJW70543.1 - 7e-37 126.1 0.0 2.3e-36 124.4 0.0 1.9 2 1 1 3 3 3 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 AJW70543.1 - 1e-07 32.0 0.5 3e-05 23.9 0.5 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AJW70543.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family TcdB_N PF12918.7 AJW70543.1 - 0.15 12.4 0.1 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain NeA_P2 PF12312.8 AJW70543.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein CPSase_L_D2 PF02786.17 AJW70544.1 - 1.1e-100 335.4 0.1 2.4e-73 246.1 0.1 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AJW70544.1 - 1.1e-35 122.6 0.0 2.4e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 AJW70544.1 - 2e-18 66.6 0.5 9.6e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJW70544.1 - 5e-15 55.6 1.4 1.3e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 AJW70544.1 - 5.8e-13 48.8 0.0 2.2e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain GARS_A PF01071.19 AJW70544.1 - 7.3e-12 45.5 0.8 4.3e-05 23.4 0.0 2.7 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 AJW70544.1 - 4.8e-11 42.5 0.0 1.6e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 AJW70544.1 - 6.7e-07 29.5 1.1 0.00084 19.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.10 AJW70544.1 - 0.014 15.0 0.0 0.042 13.4 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Vps5 PF09325.10 AJW70544.1 - 0.039 13.5 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 Vps5 C terminal like TrkA_N PF02254.18 AJW70544.1 - 0.076 13.3 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Metallophos PF00149.28 AJW70545.1 - 1.8e-09 38.4 0.5 8.2e-09 36.2 0.5 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AJW70545.1 - 2.1e-07 31.3 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AJW70545.1 - 0.034 13.5 0.1 0.92 8.8 0.1 2.2 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Epimerase_2 PF02350.19 AJW70545.1 - 0.046 12.6 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase RecX PF02631.16 AJW70548.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 RecX family ATP-synt_F PF01990.17 AJW70549.1 - 5.8e-13 49.0 0.1 6.1e-13 48.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Trp_syntA PF00290.20 AJW70549.1 - 0.044 12.6 0.0 0.044 12.6 0.0 1.0 1 0 0 1 1 1 0 Tryptophan synthase alpha chain LUD_dom PF02589.15 AJW70549.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 LUD domain ADH_N PF08240.12 AJW70550.1 - 2e-23 82.4 2.1 3.6e-23 81.5 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJW70550.1 - 4.5e-18 65.5 0.0 6.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AJW70550.1 - 4.9e-12 45.8 0.0 7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 AJW70550.1 - 1.8e-07 32.3 0.0 3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoC PF01791.9 AJW70551.1 - 4e-21 75.7 0.0 5.2e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase ThiG PF05690.14 AJW70551.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG SnoaL_3 PF13474.6 AJW70552.1 - 8.4e-09 35.7 0.0 1.1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AJW70552.1 - 2.2e-06 28.0 0.0 2.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.10 AJW70552.1 - 8.9e-06 25.9 0.1 2.7e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain TPP_enzyme_N PF02776.18 AJW70553.1 - 1.9e-61 206.6 0.8 7.8e-59 198.1 0.3 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AJW70553.1 - 2.3e-47 160.2 0.1 4.8e-47 159.1 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AJW70553.1 - 5.4e-47 159.4 0.8 2.5e-46 157.3 0.1 2.5 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 AJW70553.1 - 0.0065 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Middle domain of thiamine pyrophosphate ALS_ss_C PF10369.9 AJW70554.1 - 2.5e-23 82.1 0.5 5.4e-22 77.8 0.0 2.3 2 1 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 AJW70554.1 - 2.5e-14 52.8 0.0 4.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AJW70554.1 - 2.3e-13 49.6 0.2 7.2e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AJW70554.1 - 0.0021 18.6 0.2 0.0058 17.2 0.2 1.8 1 0 0 1 1 1 1 ACT domain DUF2344 PF10105.9 AJW70554.1 - 0.036 13.9 0.1 0.044 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) SLS PF14611.6 AJW70554.1 - 0.038 13.8 0.2 0.042 13.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator TipAS PF07739.13 AJW70554.1 - 0.044 14.3 0.1 0.058 14.0 0.1 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain BMF PF15185.6 AJW70554.1 - 0.13 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis HMGL-like PF00682.19 AJW70555.1 - 4e-87 292.1 0.5 6.3e-87 291.5 0.5 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AJW70555.1 - 3.3e-29 101.4 1.1 6.1e-29 100.6 1.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4147 PF13660.6 AJW70555.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Iso_dh PF00180.20 AJW70556.1 - 7.5e-103 344.3 0.4 8.4e-103 344.2 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 AJW70556.1 - 0.00064 19.2 0.1 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal phosphate biosynthetic protein PdxA SeqA_N PF17206.3 AJW70556.1 - 0.083 12.2 0.1 0.7 9.3 0.0 2.5 2 0 0 2 2 2 0 SeqA protein N-terminal domain E1-E2_ATPase PF00122.20 AJW70558.1 - 0.018 14.6 0.6 0.021 14.4 0.6 1.0 1 0 0 1 1 1 0 E1-E2 ATPase nlz1 PF12402.8 AJW70558.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 PsbX PF06596.11 AJW70558.1 - 0.097 12.7 1.1 0.19 11.7 1.1 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF2207 PF09972.9 AJW70558.1 - 0.13 11.0 0.2 0.14 10.9 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_trans_2_3 PF13632.6 AJW70558.1 - 0.25 11.3 1.1 0.31 10.9 1.1 1.0 1 0 0 1 1 1 0 Glycosyl transferase family group 2 NAPRTase PF04095.16 AJW70559.1 - 0.059 13.0 0.1 0.064 12.9 0.1 1.0 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Swi3 PF07962.12 AJW70559.1 - 0.12 12.4 0.1 0.12 12.4 0.1 1.2 1 1 0 1 1 1 0 Replication Fork Protection Component Swi3 tRNA-synt_2 PF00152.20 AJW70560.1 - 1.4e-87 293.7 0.0 1.9e-87 293.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AJW70560.1 - 4.3e-12 45.9 1.7 8.1e-12 45.0 1.7 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AJW70560.1 - 0.00087 18.8 0.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) KH_5 PF13184.6 AJW70561.1 - 0.0056 16.7 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 NusA-like KH domain Zn_Tnp_IS1595 PF12760.7 AJW70561.1 - 0.16 12.0 0.1 1.2 9.1 0.1 2.3 2 1 0 2 2 2 0 Transposase zinc-ribbon domain ABC_tran PF00005.27 AJW70562.1 - 4.2e-25 88.8 0.0 5.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AJW70562.1 - 4.8e-18 65.4 0.2 7.4e-18 64.8 0.2 1.3 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AJW70562.1 - 1.3e-05 25.2 2.2 6e-05 23.0 0.4 2.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJW70562.1 - 0.0012 18.3 2.0 0.011 15.1 2.4 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain PRK PF00485.18 AJW70562.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Nkap_C PF06047.11 AJW70563.1 - 0.079 13.1 4.2 0.092 12.9 4.2 1.2 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain MMtag PF10159.9 AJW70563.1 - 0.22 11.9 3.7 9.6 6.6 0.1 2.1 1 1 1 2 2 2 0 Multiple myeloma tumor-associated SNARE_assoc PF09335.11 AJW70565.1 - 1.1e-16 61.5 1.3 1.1e-16 61.5 1.3 2.0 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF1418 PF07214.12 AJW70565.1 - 0.034 14.0 2.1 0.16 11.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Pur_DNA_glyco PF02245.16 AJW70566.1 - 6.2e-64 214.6 0.0 6.9e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) DUF2141 PF09912.9 AJW70566.1 - 0.045 13.7 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) UDG PF03167.19 AJW70567.1 - 3.1e-41 141.0 0.0 3.8e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Lipase_GDSL PF00657.22 AJW70567.1 - 0.12 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase PmbA_TldD PF01523.16 AJW70568.1 - 2.9e-55 188.1 0.0 3.5e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Imm75 PF15660.6 AJW70568.1 - 0.17 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative Immunity protein 75 HATPase_c PF02518.26 AJW70570.1 - 1.1e-24 87.0 0.1 1.1e-24 87.0 0.1 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW70570.1 - 2.3e-14 53.1 0.4 7.7e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AJW70570.1 - 4.2e-08 33.5 0.0 1.6e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 AJW70570.1 - 1.2e-06 28.4 0.1 3.2e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW70570.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HopW1-1 PF15457.6 AJW70570.1 - 0.11 11.8 0.2 0.24 10.6 0.2 1.5 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Tetraspanin PF00335.20 AJW70570.1 - 0.12 12.1 0.5 0.23 11.2 0.1 1.7 2 0 0 2 2 2 0 Tetraspanin family DUF1582 PF07621.11 AJW70570.1 - 0.23 11.4 0.1 0.42 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) Hpt PF01627.23 AJW70571.1 - 7.7e-07 29.3 0.0 9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Hpt domain Response_reg PF00072.24 AJW70572.1 - 1.4e-27 96.1 1.0 1.6e-27 95.9 1.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain 3HCDH_RFF PF18321.1 AJW70572.1 - 0.037 14.5 0.0 0.072 13.5 0.0 1.5 1 1 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain T2SSE PF00437.20 AJW70573.1 - 4.3e-11 42.4 0.0 7.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.29 AJW70573.1 - 1.3e-09 37.7 0.1 8.3e-09 35.2 0.1 2.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 AJW70573.1 - 1.3e-06 28.1 0.6 6.8e-06 25.8 0.1 2.4 2 0 0 2 2 2 1 KH domain KH_5 PF13184.6 AJW70573.1 - 3.3e-05 23.9 0.1 0.00014 21.8 0.1 2.2 1 0 0 1 1 1 1 NusA-like KH domain AAA_16 PF13191.6 AJW70573.1 - 7.4e-05 23.2 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PIN_4 PF13638.6 AJW70573.1 - 0.00011 22.5 0.1 0.00036 20.8 0.1 1.9 1 1 0 1 1 1 1 PIN domain AAA_14 PF13173.6 AJW70573.1 - 0.0011 19.0 0.0 0.0034 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AJW70573.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 AJW70573.1 - 0.0013 17.8 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 AJW70573.1 - 0.0016 19.0 0.1 0.0085 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AJW70573.1 - 0.0027 18.2 0.2 0.03 14.8 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 AJW70573.1 - 0.0061 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AJW70573.1 - 0.011 16.0 0.2 0.066 13.5 0.0 2.3 3 0 0 3 3 2 0 AAA domain PIN_9 PF18477.1 AJW70573.1 - 0.014 15.7 0.7 0.44 10.9 0.2 2.8 2 1 0 2 2 1 0 PIN like domain AAA_30 PF13604.6 AJW70573.1 - 0.017 14.9 0.1 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AJW70573.1 - 0.023 14.0 0.0 0.06 12.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 AJW70573.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 AJW70573.1 - 0.024 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 AJW70573.1 - 0.037 13.2 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 AJW70573.1 - 0.041 13.8 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 AJW70573.1 - 0.051 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AJW70573.1 - 0.055 13.6 0.2 0.22 11.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 AJW70573.1 - 0.061 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 AJW70573.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 AJW70573.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Baculo_LEF-10 PF07206.11 AJW70573.1 - 0.15 12.2 0.0 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) Fe_dep_repress PF01325.19 AJW70574.1 - 1.1e-18 67.1 0.3 1.9e-18 66.4 0.3 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 AJW70574.1 - 3.5e-14 52.6 0.0 6.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain DUF4423 PF14394.6 AJW70574.1 - 0.00021 21.1 0.0 0.0016 18.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) TrmB PF01978.19 AJW70574.1 - 0.00074 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AJW70574.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 MarR family LexA_DNA_bind PF01726.16 AJW70574.1 - 0.0024 17.6 0.0 0.0094 15.7 0.0 2.0 3 0 0 3 3 2 1 LexA DNA binding domain MarR PF01047.22 AJW70574.1 - 0.0032 17.3 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 MarR family DUF2250 PF10007.9 AJW70574.1 - 0.0041 17.2 0.1 0.0094 16.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HipN PF18253.1 AJW70574.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain HTH_45 PF14947.6 AJW70574.1 - 0.01 15.8 0.4 0.029 14.4 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix HTH_Crp_2 PF13545.6 AJW70574.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_27 PF13463.6 AJW70574.1 - 0.015 15.7 0.0 0.088 13.3 0.0 2.2 2 1 0 2 2 2 0 Winged helix DNA-binding domain HTH_24 PF13412.6 AJW70574.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 AJW70574.1 - 0.021 14.8 0.0 0.09 12.8 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_12 PF08461.10 AJW70574.1 - 0.026 14.4 0.1 0.074 13.0 0.1 1.8 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain WYL_3 PF18488.1 AJW70574.1 - 0.034 14.5 0.2 0.12 12.7 0.0 2.0 2 1 0 2 2 2 0 WYL domain HTH_IclR PF09339.10 AJW70574.1 - 0.065 13.0 0.4 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HemN_C PF06969.16 AJW70574.1 - 0.11 12.6 0.0 3.4 7.8 0.0 2.4 1 1 1 2 2 2 0 HemN C-terminal domain Rrf2 PF02082.20 AJW70574.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 AJW70574.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 AJW70574.1 - 0.13 12.1 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.18 AJW70574.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain DUF192 PF02643.15 AJW70577.1 - 1.3e-30 105.4 0.0 1.8e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 TauE PF01925.19 AJW70579.1 - 6.6e-54 183.0 34.6 7.8e-54 182.8 34.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF5423 PF17461.2 AJW70579.1 - 2 7.2 4.0 0.43 9.4 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5423) SepZ PF06066.11 AJW70579.1 - 8.4 6.7 10.7 1.8 8.8 0.7 3.2 3 1 0 3 3 3 0 SepZ SnoaL_3 PF13474.6 AJW70580.1 - 0.06 13.6 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Gal4_dimer PF03902.13 AJW70580.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 1 1 2 2 2 0 Gal4-like dimerisation domain adh_short PF00106.25 AJW70581.1 - 1.8e-41 141.7 0.1 3.2e-34 118.1 0.0 3.0 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 AJW70581.1 - 6.8e-37 127.3 0.0 8.6e-26 90.9 0.0 3.5 3 1 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AJW70581.1 - 7e-16 58.6 0.1 4.3e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 AJW70581.1 - 8.8e-06 25.4 0.1 7.6e-05 22.3 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 AJW70581.1 - 0.00058 20.4 0.3 0.0033 18.0 0.2 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 AJW70581.1 - 0.00088 18.5 0.2 0.0022 17.2 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 AJW70581.1 - 0.002 17.6 0.1 0.01 15.2 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Zw10 PF06248.13 AJW70581.1 - 0.016 13.8 0.8 0.022 13.3 0.3 1.4 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 3HCDH_N PF02737.18 AJW70581.1 - 0.018 14.9 1.1 0.027 14.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA_int_endo PF01974.17 AJW70584.1 - 4.2e-27 94.0 0.0 6.4e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 AJW70584.1 - 3.6e-19 68.2 0.0 6.5e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain PhoU_div PF01865.16 AJW70585.1 - 5.9e-19 68.3 10.0 7e-19 68.0 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 DUF677 PF05055.12 AJW70585.1 - 0.0047 15.9 0.7 0.0047 15.9 0.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF677) PhoU PF01895.19 AJW70585.1 - 0.013 16.0 12.3 0.055 13.9 2.8 3.0 2 1 1 3 3 3 0 PhoU domain RNaseH_like PF04308.12 AJW70585.1 - 0.046 13.6 6.1 2.6 8.0 0.0 3.0 1 1 1 3 3 3 0 Ribonuclease H-like WD40_alt PF14077.6 AJW70585.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.4 3 0 0 3 3 3 0 Alternative WD40 repeat motif COG2 PF06148.11 AJW70585.1 - 0.41 10.7 8.1 2.1 8.4 0.1 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 AJW70585.1 - 0.47 10.8 7.5 1.8 8.9 0.2 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 AJW70585.1 - 0.55 9.4 3.7 0.23 10.7 0.4 1.8 2 0 0 2 2 2 0 Invariant surface glycoprotein MCPsignal PF00015.21 AJW70585.1 - 0.75 9.6 10.9 1.8 8.4 8.4 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PCRF PF03462.18 AJW70585.1 - 1.4 8.8 4.7 2.6 7.9 0.5 2.2 2 0 0 2 2 2 0 PCRF domain DUF2203 PF09969.9 AJW70585.1 - 1.5 9.6 6.5 3.6 8.3 1.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Lzipper-MIP1 PF14389.6 AJW70585.1 - 3.7 7.9 9.5 1.8 8.9 1.8 2.9 2 2 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DNA_ligase_A_M PF01068.21 AJW70586.1 - 3.7e-60 203.1 1.8 7.1e-60 202.2 1.8 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 AJW70586.1 - 1.4e-36 126.4 1.2 1.4e-36 126.4 1.2 1.6 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 AJW70586.1 - 4.3e-21 75.4 0.0 8.4e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 AJW70586.1 - 2.5e-06 27.9 0.5 4.8e-06 27.0 0.3 1.6 2 0 0 2 2 2 1 RNA ligase MASE3 PF17159.4 AJW70588.1 - 0.0049 16.5 0.1 0.0074 15.9 0.1 1.2 1 0 0 1 1 1 1 Membrane-associated sensor domain FBPase_3 PF01950.16 AJW70589.1 - 2e-150 501.0 0.1 2.3e-150 500.8 0.1 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase GTP_EFTU PF00009.27 AJW70590.1 - 9.5e-47 159.1 0.1 1.4e-46 158.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AJW70590.1 - 6.7e-37 126.2 0.4 1.6e-36 125.0 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AJW70590.1 - 2e-15 56.9 2.2 2.8e-15 56.4 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 AJW70590.1 - 0.00026 20.8 1.0 0.00061 19.6 1.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 NIF3 PF01784.18 AJW70590.1 - 0.095 12.3 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) FAM25 PF15825.5 AJW70590.1 - 5.1 7.5 6.4 0.6 10.5 0.4 2.5 3 0 0 3 3 3 0 FAM25 family Ribosomal_S10 PF00338.22 AJW70591.1 - 2.7e-22 78.8 0.0 3e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CTX_RstB PF07459.11 AJW70591.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 CTX phage RstB protein DNA_RNApol_7kD PF03604.13 AJW70592.1 - 0.00029 20.5 1.2 0.00049 19.7 1.2 1.4 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 AJW70592.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 AJW70593.1 - 6.4e-11 42.1 7.5 1.5e-05 25.2 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJW70593.1 - 1.6e-08 34.7 5.7 0.0019 18.9 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 AJW70593.1 - 2.8e-08 33.9 10.9 6.2e-05 23.2 1.2 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 AJW70593.1 - 8.4e-06 25.8 5.2 0.002 18.2 0.3 2.1 1 1 1 2 2 2 2 Zic proteins zinc finger domain zf-met PF12874.7 AJW70593.1 - 1.3e-05 25.4 5.8 0.01 16.2 0.5 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 AJW70593.1 - 1.5e-05 24.9 5.9 0.026 14.5 0.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF629 PF04780.12 AJW70593.1 - 8.4e-05 21.3 7.9 0.012 14.2 1.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf_UBZ PF18439.1 AJW70593.1 - 0.00022 20.7 4.6 0.11 12.2 1.0 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 AJW70593.1 - 0.00023 21.8 0.9 0.0017 19.0 1.0 1.8 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 AJW70593.1 - 0.00044 20.5 12.5 0.023 15.1 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 AJW70593.1 - 0.001 18.7 1.2 0.017 14.8 0.1 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-BED PF02892.15 AJW70593.1 - 0.0012 18.8 7.1 0.23 11.5 1.1 2.2 1 1 1 2 2 2 2 BED zinc finger zf-C2HE PF16278.5 AJW70593.1 - 0.0023 18.3 1.8 0.0023 18.3 1.8 2.0 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 AJW70593.1 - 0.0027 18.0 10.9 0.19 12.0 2.8 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Endonuclease_7 PF02945.15 AJW70593.1 - 0.0054 16.6 1.3 0.0071 16.2 1.3 1.2 1 0 0 1 1 1 1 Recombination endonuclease VII FOXP-CC PF16159.5 AJW70593.1 - 0.013 16.1 4.2 0.69 10.6 0.3 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain CpXC PF14353.6 AJW70593.1 - 0.027 14.5 2.3 1.4 9.0 0.2 2.0 1 1 1 2 2 2 0 CpXC protein zinc-ribbons_6 PF07191.12 AJW70593.1 - 0.084 12.9 4.7 0.18 11.8 4.6 1.6 1 1 0 1 1 1 0 zinc-ribbons zf-Di19 PF05605.12 AJW70593.1 - 0.1 12.9 5.6 0.35 11.2 5.4 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding SIR2 PF02146.17 AJW70593.1 - 0.12 12.3 3.0 4.5 7.2 0.2 1.9 1 1 1 2 2 2 0 Sir2 family OrsD PF12013.8 AJW70593.1 - 0.13 12.7 4.1 0.44 11.0 4.1 1.7 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Zn-ribbon_8 PF09723.10 AJW70593.1 - 0.15 12.2 8.8 1.9 8.7 1.1 2.1 1 1 1 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 AJW70593.1 - 0.15 12.3 4.8 0.27 11.5 4.8 1.4 1 1 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_8 PF15909.5 AJW70593.1 - 0.2 12.0 2.5 7.1 7.0 0.2 1.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon Sprouty PF05210.13 AJW70593.1 - 0.23 11.8 3.6 7.2 7.0 0.2 2.0 2 0 0 2 2 2 0 Sprouty protein (Spry) PyrI_C PF02748.15 AJW70593.1 - 0.29 11.1 7.6 0.28 11.1 0.4 2.3 1 1 2 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C4pol PF14260.6 AJW70594.1 - 0.001 19.5 8.9 0.33 11.5 0.5 3.2 2 1 1 3 3 3 2 C4-type zinc-finger of DNA polymerase delta Ribosomal_S14 PF00253.21 AJW70594.1 - 0.077 12.8 2.6 7.2 6.5 0.0 2.9 2 1 0 2 2 2 0 Ribosomal protein S14p/S29e DUF4428 PF14471.6 AJW70594.1 - 0.5 10.3 22.5 0.18 11.7 0.9 4.5 3 2 0 3 3 3 0 Domain of unknown function (DUF4428) Cytochrome_C7 PF14522.6 AJW70594.1 - 0.54 10.3 16.4 1 9.4 4.3 3.0 2 1 1 3 3 3 0 Cytochrome c7 and related cytochrome c C1_1 PF00130.22 AJW70594.1 - 1.6 8.7 18.2 2 8.3 5.0 3.4 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.6 AJW70594.1 - 2.2 8.2 22.1 0.94 9.4 2.4 4.5 4 1 1 5 5 5 0 Prokaryotic RING finger family 4 Cytochrom_c3_2 PF14537.6 AJW70594.1 - 3 8.4 17.3 3.2e+02 1.9 17.3 3.2 1 1 0 1 1 1 0 Cytochrome c3 LDcluster4 PF18306.1 AJW70596.1 - 4.7e-45 153.0 1.9 5.5e-45 152.8 1.9 1.1 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 AJW70596.1 - 0.00047 20.3 0.5 0.0029 17.7 0.5 2.2 1 1 0 1 1 1 1 Possible lysine decarboxylase DNA_processg_A PF02481.15 AJW70596.1 - 0.0013 18.0 1.0 0.01 15.1 0.2 2.2 2 1 0 2 2 2 1 DNA recombination-mediator protein A DAGK_cat PF00781.24 AJW70596.1 - 0.005 16.4 1.3 0.4 10.3 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain 3HCDH_N PF02737.18 AJW70597.1 - 1.9e-66 223.4 1.0 1.9e-66 223.4 1.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AJW70597.1 - 5.8e-35 119.8 0.1 4.5e-26 91.3 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AJW70597.1 - 3.1e-06 27.4 0.0 6.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AJW70597.1 - 7.6e-06 26.0 0.3 2.3e-05 24.4 0.3 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AJW70597.1 - 0.0016 19.0 0.2 0.0052 17.3 0.2 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF4078 PF13300.6 AJW70597.1 - 0.032 14.5 0.1 0.055 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) AlaDh_PNT_C PF01262.21 AJW70597.1 - 0.044 13.1 0.5 0.12 11.6 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AJW70597.1 - 0.081 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1803 PF08820.10 AJW70597.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) IlvN PF07991.12 AJW70597.1 - 1.8 8.1 4.3 83 2.7 4.3 2.4 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain zf-C2H2_4 PF13894.6 AJW70598.1 - 0.00014 22.4 0.7 0.0002 21.9 0.7 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.15 AJW70598.1 - 0.001 19.0 0.3 0.0017 18.4 0.3 1.3 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.26 AJW70598.1 - 0.002 18.5 1.1 0.0031 17.9 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 AJW70598.1 - 0.012 15.9 0.2 0.013 15.9 0.2 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-CpG_bind_C PF12269.8 AJW70598.1 - 0.06 13.1 0.2 0.066 13.0 0.2 1.0 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain zf-C2H2_12 PF18658.1 AJW70598.1 - 0.094 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type Actin_micro PF17003.5 AJW70598.1 - 0.13 11.4 0.4 0.15 11.2 0.4 1.0 1 0 0 1 1 1 0 Putative actin-like family HIT PF01230.23 AJW70600.1 - 6.3e-23 81.4 0.9 7.8e-23 81.1 0.9 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AJW70600.1 - 4.6e-13 49.6 0.6 6.5e-13 49.2 0.6 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 AJW70600.1 - 0.00025 20.9 0.2 0.00033 20.5 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 AJW70600.1 - 0.0036 17.1 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DnaJ PF00226.31 AJW70601.1 - 2e-19 69.5 1.9 5.3e-19 68.1 1.9 1.7 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 AJW70601.1 - 3.1e-10 40.4 3.3 3.1e-10 40.4 3.3 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AJW70601.1 - 1.8e-06 28.6 4.4 8.9e-06 26.4 4.4 2.1 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 AJW70601.1 - 0.066 13.3 3.1 0.22 11.6 3.1 1.9 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 AJW70601.1 - 0.12 12.2 10.9 0.36 10.7 6.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Cupin_2 PF07883.11 AJW70602.1 - 2.1e-12 46.6 0.0 3.9e-12 45.7 0.0 1.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 AJW70602.1 - 4.5e-05 23.1 0.0 5.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 AJW70602.1 - 5.1e-05 22.9 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 AJW70602.1 - 0.00019 21.4 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 AJW70602.1 - 0.00048 20.1 0.0 0.00058 19.8 0.0 1.2 1 1 0 1 1 1 1 Mannose-6-phosphate isomerase Ectoine_synth PF06339.12 AJW70602.1 - 0.00097 19.3 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.11 AJW70603.1 - 2e-07 30.6 0.6 9.8e-07 28.4 0.6 1.9 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 AJW70603.1 - 1.8e-05 24.5 0.1 2e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Auxin binding protein Cupin_1 PF00190.22 AJW70603.1 - 1.9e-05 24.3 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 AJW70603.1 - 0.11 12.4 0.1 0.34 10.8 0.1 1.7 1 1 0 1 1 1 0 AraC-like ligand binding domain SHOCT PF09851.9 AJW70604.1 - 1.2e-06 28.1 5.2 1.2e-06 28.1 5.2 2.7 3 0 0 3 3 3 1 Short C-terminal domain ApoLp-III PF07464.11 AJW70604.1 - 0.064 13.3 5.6 0.088 12.9 5.6 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) REF PF05755.12 AJW70604.1 - 0.078 12.8 0.6 0.094 12.5 0.6 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Toprim_Crpt PF13342.6 AJW70605.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase TPR_1 PF00515.28 AJW70606.1 - 1.3e-38 129.2 18.8 9.3e-08 31.6 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 AJW70606.1 - 1.2e-37 125.0 9.3 2e-06 27.5 0.9 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 AJW70606.1 - 7.4e-30 102.4 11.0 8.4e-08 31.8 0.3 6.9 3 2 4 7 7 7 6 TPR repeat TPR_17 PF13431.6 AJW70606.1 - 6.7e-27 91.9 10.5 6e-06 26.3 0.1 6.6 8 1 1 9 9 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 AJW70606.1 - 6.8e-25 87.5 0.0 1.5e-07 31.9 0.0 5.0 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 AJW70606.1 - 1.2e-23 81.7 0.0 0.022 15.6 0.0 7.1 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 AJW70606.1 - 2.9e-23 80.9 2.1 0.01 16.4 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 AJW70606.1 - 4.4e-23 79.5 12.3 8.5e-06 25.6 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 AJW70606.1 - 9.4e-20 70.9 3.4 5.1e-05 23.7 0.0 4.2 3 1 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AJW70606.1 - 4.8e-17 61.9 2.7 6e-05 23.2 0.3 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AJW70606.1 - 4.1e-15 55.8 5.3 4.8e-05 23.6 1.7 5.5 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 AJW70606.1 - 3.2e-13 48.7 0.0 0.095 12.8 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 AJW70606.1 - 5.7e-13 48.8 0.0 5.3e-07 29.7 0.0 3.5 1 1 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 AJW70606.1 - 7.2e-11 41.7 5.8 0.00048 19.2 0.7 3.1 1 1 2 3 3 3 3 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 AJW70606.1 - 1.5e-08 34.2 7.4 0.035 14.0 0.7 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 AJW70606.1 - 1.7e-07 31.5 4.3 0.083 13.2 0.1 4.4 1 1 3 5 5 5 2 Tetratricopeptide repeat MIT PF04212.18 AJW70606.1 - 1.8e-06 27.9 13.3 0.22 11.6 0.1 6.3 4 2 3 7 7 7 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 AJW70606.1 - 4.5e-06 26.6 10.8 0.21 11.7 0.0 6.2 3 2 4 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 AJW70606.1 - 9.3e-06 25.3 2.7 0.16 11.3 0.2 3.2 1 1 2 3 3 3 2 Coatomer epsilon subunit DUF3856 PF12968.7 AJW70606.1 - 0.00018 21.6 0.4 8.5 6.4 0.0 4.4 1 1 3 4 4 4 0 Domain of Unknown Function (DUF3856) SRP_TPR_like PF17004.5 AJW70606.1 - 0.00029 20.8 4.5 0.26 11.3 0.6 3.4 1 1 2 4 4 4 2 Putative TPR-like repeat PPR PF01535.20 AJW70606.1 - 0.00031 20.8 1.1 3.1 8.3 0.0 5.2 5 0 0 5 5 4 1 PPR repeat Rapsyn_N PF10579.9 AJW70606.1 - 0.00098 19.2 0.1 1.4 9.1 0.0 4.0 2 2 2 4 4 4 1 Rapsyn N-terminal myristoylation and linker region BTAD PF03704.17 AJW70606.1 - 0.0011 19.4 0.2 0.16 12.4 0.0 3.4 1 1 2 3 3 3 1 Bacterial transcriptional activator domain Thioredoxin_6 PF13848.6 AJW70606.1 - 0.003 17.5 1.2 0.25 11.2 0.2 3.1 3 1 0 3 3 3 1 Thioredoxin-like domain HrpB1_HrpK PF09613.10 AJW70606.1 - 0.0044 16.6 0.0 0.23 11.1 0.0 2.7 2 2 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) Alkyl_sulf_dimr PF14863.6 AJW70606.1 - 0.0093 16.4 1.1 5.8 7.4 0.0 3.4 1 1 0 3 3 3 0 Alkyl sulfatase dimerisation RPN7 PF10602.9 AJW70606.1 - 0.011 15.4 0.4 0.97 9.1 0.3 3.2 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 AJW70606.1 - 0.019 14.7 1.4 0.17 11.6 0.3 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain DUF627 PF04781.12 AJW70606.1 - 0.019 15.0 1.2 6.8 6.8 0.1 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF627) DUF247 PF03140.15 AJW70606.1 - 0.048 12.9 0.3 1.1 8.4 0.1 2.7 2 1 1 3 3 3 0 Plant protein of unknown function HPS6 PF15702.5 AJW70606.1 - 0.053 11.5 0.0 0.07 11.1 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein TOM20_plant PF06552.12 AJW70606.1 - 0.067 12.9 3.6 7.3 6.3 0.4 4.0 1 1 2 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 RAP-1 PF03085.15 AJW70606.1 - 0.072 12.8 0.3 0.072 12.8 0.3 1.9 2 1 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) ANAPC5 PF12862.7 AJW70606.1 - 0.081 13.0 1.1 0.76 9.9 0.3 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 Clathrin PF00637.20 AJW70606.1 - 0.64 9.9 4.4 6.5 6.6 0.5 3.6 1 1 2 3 3 3 0 Region in Clathrin and VPS DUF11 PF01345.18 AJW70608.1 - 5.3e-40 135.6 16.2 1.3e-16 60.6 3.2 9.0 7 2 1 8 8 6 3 Domain of unknown function DUF11 HYR PF02494.16 AJW70608.1 - 7.2e-35 119.2 82.3 3.3e-16 59.4 1.2 10.6 11 1 0 11 11 11 6 HYR domain Big_9 PF17963.1 AJW70608.1 - 8.1e-15 55.3 23.6 4.9e-14 52.8 9.1 16.5 7 4 5 13 13 5 2 Bacterial Ig domain Calx-beta PF03160.14 AJW70608.1 - 5.1e-09 36.2 0.7 5.1e-09 36.2 0.7 2.9 2 0 0 2 2 2 1 Calx-beta domain Cadherin_5 PF17892.1 AJW70608.1 - 6.7e-09 35.6 2.4 6.7e-09 35.6 2.4 7.9 7 1 1 8 8 8 1 Cadherin-like domain TRAP_beta PF05753.14 AJW70608.1 - 5.9e-06 25.8 3.3 0.38 10.1 0.3 3.8 3 0 0 3 3 3 2 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 AJW70608.1 - 0.00021 21.5 26.5 0.11 12.8 4.7 8.0 5 3 0 5 5 5 3 CARDB He_PIG PF05345.12 AJW70608.1 - 0.0023 18.1 4.1 0.0023 18.1 4.1 13.8 12 2 1 13 13 12 1 Putative Ig domain Big_3_5 PF16640.5 AJW70608.1 - 0.0031 17.7 3.6 0.0031 17.7 3.6 13.2 8 4 6 16 16 9 1 Bacterial Ig-like domain (group 3) bMG10 PF17973.1 AJW70608.1 - 0.016 15.4 4.1 0.69 10.1 0.0 4.7 5 0 0 5 5 5 0 Bacterial Alpha-2-macroglobulin MG10 domain Chlam_OMP6 PF03504.13 AJW70608.1 - 0.027 14.8 6.6 13 6.1 0.1 5.0 5 0 0 5 5 5 0 Chlamydia cysteine-rich outer membrane protein 6 NPCBM_assoc PF10633.9 AJW70608.1 - 0.037 14.3 0.1 0.037 14.3 0.1 8.1 10 0 0 10 10 8 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4398 PF14346.6 AJW70608.1 - 0.28 11.8 6.2 0.62 10.7 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) HATPase_c PF02518.26 AJW70609.1 - 3.4e-21 75.9 3.3 2e-20 73.3 0.1 2.6 1 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW70609.1 - 2.1e-11 43.7 0.1 4.7e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW70609.1 - 2.2e-10 40.3 0.4 1.4e-09 37.8 0.0 2.4 2 1 1 3 3 3 1 GHKL domain HATPase_c_3 PF13589.6 AJW70609.1 - 0.00052 19.9 0.4 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW70609.1 - 0.0042 17.0 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain FlaC_arch PF05377.11 AJW70609.1 - 0.43 11.0 3.3 0.72 10.3 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Trypan_PARP PF05887.11 AJW70610.1 - 1.7 8.6 16.5 4.4 7.3 16.3 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Fungal_TACC PF12709.7 AJW70613.1 - 0.0043 17.5 5.0 0.01 16.2 5.0 1.6 1 1 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins DUF445 PF04286.12 AJW70613.1 - 0.029 14.2 0.2 0.029 14.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2294 PF10057.9 AJW70613.1 - 0.05 13.7 0.2 2.8 8.1 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) DnaB_2 PF07261.11 AJW70613.1 - 0.05 13.3 0.6 0.73 9.6 0.5 2.2 1 1 0 1 1 1 0 Replication initiation and membrane attachment Peptidase_M10 PF00413.24 AJW70615.1 - 1.7e-09 37.7 0.3 2.7e-09 37.1 0.3 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 AJW70615.1 - 0.0037 17.5 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 AJW70615.1 - 0.0044 16.7 0.7 0.03 13.9 0.1 2.2 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 AJW70615.1 - 0.0048 17.4 0.6 0.013 16.0 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 AJW70615.1 - 0.0087 16.0 1.4 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease DUF4953 PF16313.5 AJW70615.1 - 0.01 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 AJW70615.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 AJW70615.1 - 0.012 15.2 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 AJW70615.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 AJW70615.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like HxlR PF01638.17 AJW70616.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.5 1 1 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 AJW70616.1 - 0.05 13.6 0.0 0.18 11.8 0.0 1.8 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family ADK PF00406.22 AJW70616.1 - 0.064 13.4 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Adenylate kinase Melibiase PF02065.18 AJW70617.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Melibiase Aminotran_3 PF00202.21 AJW70619.1 - 5.5e-58 196.5 0.0 7.5e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF4499 PF14934.6 AJW70620.1 - 0.027 14.8 0.0 0.028 14.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) DUF2180 PF09947.9 AJW70623.1 - 0.091 12.7 3.7 0.18 11.8 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) TackOD1 PF18551.1 AJW70624.1 - 0.001 18.8 0.5 0.001 18.8 0.5 1.0 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 DZR PF12773.7 AJW70624.1 - 0.0017 18.3 0.5 0.0022 18.0 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn_ribbon_SprT PF17283.2 AJW70624.1 - 0.0023 17.8 2.2 0.37 10.7 2.9 2.1 1 1 1 2 2 2 2 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 AJW70624.1 - 0.0023 17.9 0.4 0.0026 17.7 0.4 1.1 1 0 0 1 1 1 1 zinc-ribbons A2L_zn_ribbon PF08792.10 AJW70624.1 - 0.0036 17.0 3.9 0.092 12.5 0.3 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain TFIIS_C PF01096.18 AJW70624.1 - 0.0089 15.9 3.1 0.018 14.9 0.4 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) FYVE PF01363.21 AJW70624.1 - 0.01 16.0 0.5 0.011 15.8 0.5 1.1 1 0 0 1 1 1 0 FYVE zinc finger HypA PF01155.19 AJW70624.1 - 0.01 15.8 0.8 0.011 15.7 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AJW70624.1 - 0.012 15.7 2.2 0.029 14.5 2.2 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 AJW70624.1 - 0.021 14.6 2.3 0.053 13.3 0.1 2.0 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_UBZ PF18439.1 AJW70624.1 - 0.023 14.3 2.3 0.036 13.7 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger FYVE_2 PF02318.16 AJW70624.1 - 0.047 13.9 0.8 0.047 13.9 0.8 1.0 1 0 0 1 1 1 0 FYVE-type zinc finger zf-Dof PF02701.15 AJW70624.1 - 0.049 13.8 1.5 0.3 11.3 1.5 1.9 1 1 0 1 1 1 0 Dof domain, zinc finger zf-RRN7 PF11781.8 AJW70624.1 - 0.071 12.8 3.3 0.14 11.9 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_4 PF13894.6 AJW70624.1 - 0.083 13.8 1.9 1.8 9.6 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 AJW70624.1 - 0.092 12.2 2.8 1.1 8.8 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 AJW70624.1 - 0.11 12.4 3.3 0.31 10.9 0.3 2.1 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 AJW70624.1 - 0.14 11.7 5.8 0.39 10.3 0.5 2.0 1 1 2 3 3 3 0 TFIIB zinc-binding zf-B_box PF00643.24 AJW70624.1 - 0.15 12.2 3.1 0.47 10.6 3.1 1.7 1 1 0 1 1 1 0 B-box zinc finger zf-C2H2 PF00096.26 AJW70624.1 - 0.22 12.0 3.1 0.82 10.2 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-trcl PF13451.6 AJW70624.1 - 0.28 11.1 4.6 0.62 10.0 0.4 2.1 1 1 1 2 2 2 0 Probable zinc-ribbon domain zf-CCHC_2 PF13696.6 AJW70624.1 - 0.74 9.7 5.3 0.91 9.4 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_6 PF13912.6 AJW70624.1 - 3.1 7.9 7.1 1 9.5 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger HATPase_c PF02518.26 AJW70626.1 - 1e-22 80.7 0.7 2.3e-22 79.6 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AJW70626.1 - 3.5e-18 65.8 0.1 7.8e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AJW70626.1 - 1.5e-14 54.0 0.0 4.7e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AJW70626.1 - 3.1e-12 46.6 0.1 6e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AJW70626.1 - 4e-10 39.9 0.0 7.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AJW70626.1 - 7.9e-09 35.4 0.0 2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW70626.1 - 1.5e-08 34.4 0.0 4.2e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AJW70626.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AJW70626.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AJW70626.1 - 0.0032 17.5 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 PAS domain Thioredoxin_11 PF18078.1 AJW70626.1 - 0.026 14.6 0.2 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like SNTX domain PAS_7 PF12860.7 AJW70626.1 - 0.13 12.4 0.0 1 9.6 0.0 2.4 1 1 1 2 2 2 0 PAS fold RDD PF06271.12 AJW70627.1 - 1.4e-18 67.4 1.1 2.1e-18 66.9 1.1 1.3 1 0 0 1 1 1 1 RDD family zf-FLZ PF04570.14 AJW70628.1 - 0.075 12.5 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Methyltransf_11 PF08241.12 AJW70629.1 - 4.4e-11 43.3 0.0 8.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW70629.1 - 4.1e-05 24.2 0.0 7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW70629.1 - 0.00067 19.5 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 AJW70629.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_12 PF08242.12 AJW70629.1 - 0.051 14.3 0.0 0.1 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AJW70629.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Robl_LC7 PF03259.17 AJW70631.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain CAP_N PF01213.19 AJW70632.1 - 0.14 11.6 0.2 0.24 10.8 0.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal JAKMIP_CC3 PF16034.5 AJW70632.1 - 0.28 11.1 1.1 0.43 10.5 1.1 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain PMSR PF01625.21 AJW70633.1 - 6.1e-67 224.6 0.8 6.6e-67 224.4 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HMA PF00403.26 AJW70633.1 - 0.056 13.9 0.3 7.5 7.1 0.0 2.9 3 0 0 3 3 3 0 Heavy-metal-associated domain Vsr PF03852.15 AJW70633.1 - 0.061 13.2 0.1 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Abhydrolase_1 PF00561.20 AJW70635.1 - 9.8e-27 94.2 0.0 2.2e-19 70.1 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AJW70635.1 - 2.1e-19 69.8 0.0 1.6e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AJW70635.1 - 8.7e-18 65.7 0.0 1.1e-17 65.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 AJW70635.1 - 0.00016 21.6 0.0 0.14 12.0 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 AJW70635.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 AJW70635.1 - 0.017 15.0 0.0 0.64 9.9 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase Abhydrolase_5 PF12695.7 AJW70635.1 - 0.022 14.5 0.0 2.3 7.9 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 AJW70635.1 - 0.07 12.8 0.0 0.17 11.5 0.0 1.7 3 0 0 3 3 3 0 Putative esterase Ndr PF03096.14 AJW70635.1 - 0.19 10.4 0.0 0.22 10.2 0.0 1.3 1 1 0 1 1 1 0 Ndr family MazE_antitoxin PF04014.18 AJW70636.1 - 0.011 15.6 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin AbrB-like PF14250.6 AJW70636.1 - 0.055 13.6 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 AbrB-like transcriptional regulator MraZ PF02381.18 AJW70636.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like Pollen_allerg_2 PF01620.16 AJW70636.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DUF2937 PF11157.8 AJW70637.1 - 0.017 14.8 1.2 2.5 7.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) RIH_assoc PF08454.11 AJW70637.1 - 0.056 13.3 1.9 0.088 12.7 1.5 1.6 1 1 0 1 1 1 0 RyR and IP3R Homology associated DUF4473 PF14747.6 AJW70637.1 - 0.37 11.4 5.7 5.2 7.7 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) Abhydrolase_1 PF00561.20 AJW70638.1 - 6.4e-15 55.5 0.0 9.9e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AJW70638.1 - 2.6e-14 53.1 0.0 2e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PhaC_N PF07167.13 AJW70638.1 - 3.5e-11 43.1 0.1 6.8e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF3141 PF11339.8 AJW70638.1 - 1.8e-08 33.3 0.0 2.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) DLH PF01738.18 AJW70638.1 - 0.00026 20.6 0.0 0.0012 18.4 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family PHB_depo_C PF06850.11 AJW70638.1 - 0.00074 19.0 0.0 0.0049 16.3 0.0 2.2 1 1 1 2 2 2 1 PHB de-polymerase C-terminus BAAT_C PF08840.11 AJW70638.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 AJW70638.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LIP PF03583.14 AJW70638.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase Peptidase_S15 PF02129.18 AJW70638.1 - 0.15 11.6 0.1 0.83 9.2 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PHA_synth_III_E PF09712.10 AJW70639.1 - 2.9e-13 49.6 0.5 6.9e-13 48.4 0.2 1.6 1 1 1 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Cnn_1N PF07989.11 AJW70639.1 - 0.00099 19.2 1.3 2.2 8.5 1.3 2.5 2 0 0 2 2 2 2 Centrosomin N-terminal motif 1 Bacillus_HBL PF05791.11 AJW70639.1 - 0.0012 18.7 1.2 0.17 11.7 0.1 2.4 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) DUF4763 PF15960.5 AJW70639.1 - 0.0057 16.0 2.3 1.1 8.5 0.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4763) DUF2408 PF10303.9 AJW70639.1 - 0.022 15.4 1.8 0.037 14.6 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) IFP_35_N PF07334.13 AJW70639.1 - 0.047 13.8 7.3 0.51 10.4 1.6 2.5 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MutS_IV PF05190.18 AJW70639.1 - 0.35 11.2 3.8 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 MutS family domain IV ApoLp-III PF07464.11 AJW70639.1 - 1.6 8.8 6.7 1.6 8.8 0.4 2.6 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) PheRS_DBD2 PF18554.1 AJW70641.1 - 0.1 12.6 0.4 0.22 11.6 0.4 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 2 TFIIB PF00382.19 AJW70642.1 - 1.1e-33 115.0 5.7 1.3e-16 60.4 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW70642.1 - 1.3e-12 47.0 1.1 2.2e-12 46.3 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 AJW70642.1 - 7.7e-05 22.4 0.3 0.0011 18.7 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-RRN7 PF11781.8 AJW70642.1 - 0.00035 20.2 0.6 0.00057 19.5 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 A2L_zn_ribbon PF08792.10 AJW70642.1 - 0.00038 20.1 1.5 0.00071 19.2 1.5 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain Ribosomal_S27e PF01667.17 AJW70642.1 - 0.003 17.2 1.6 0.0069 16.1 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27 TFIIB_C_1 PF18542.1 AJW70642.1 - 0.0087 16.1 0.7 0.0087 16.1 0.7 1.8 2 0 0 2 2 1 1 Transcription factor IIB C-terminal module 1 DUF4503 PF14951.6 AJW70642.1 - 0.0097 14.4 0.1 0.017 13.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) RPW8 PF05659.11 AJW70642.1 - 0.019 14.6 0.2 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Zn_Tnp_IS1595 PF12760.7 AJW70642.1 - 0.026 14.5 0.2 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AJW70642.1 - 0.031 14.2 0.2 0.077 12.9 0.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 AJW70642.1 - 0.033 13.6 4.2 0.13 11.7 4.2 1.9 1 1 0 1 1 1 0 zinc-ribbon domain RB_B PF01857.20 AJW70642.1 - 0.034 14.2 0.1 0.056 13.5 0.1 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain TerY_C PF15616.6 AJW70642.1 - 0.077 13.1 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain Lar_restr_allev PF14354.6 AJW70642.1 - 0.099 13.0 2.4 0.18 12.2 0.6 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar HscB_4_cys PF18256.1 AJW70642.1 - 0.18 11.6 1.9 0.36 10.7 1.9 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zinc_ribbon_2 PF13240.6 AJW70642.1 - 0.23 11.2 7.1 3.3 7.5 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TPR_1 PF00515.28 AJW70643.1 - 1.6e-13 49.8 0.0 0.00076 19.2 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AJW70643.1 - 1.3e-10 40.5 0.0 0.00047 20.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_M10 PF00413.24 AJW70643.1 - 1.2e-09 38.2 0.1 2.5e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Matrixin TPR_8 PF13181.6 AJW70643.1 - 1.7e-06 27.7 0.9 0.62 10.4 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Peptidase_M57 PF12388.8 AJW70643.1 - 6.9e-06 25.8 0.1 1.5e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase TPR_19 PF14559.6 AJW70643.1 - 1.5e-05 25.4 0.0 0.083 13.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJW70643.1 - 2.4e-05 24.5 0.1 0.05 13.9 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJW70643.1 - 4.6e-05 23.2 0.0 0.083 13.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 AJW70643.1 - 4.7e-05 23.7 0.0 0.77 10.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Reprolysin_5 PF13688.6 AJW70643.1 - 5.4e-05 23.4 0.2 0.00013 22.2 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 TPR_14 PF13428.6 AJW70643.1 - 6.4e-05 23.4 0.0 3.3 8.8 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJW70643.1 - 0.00026 20.6 0.3 1.1 9.0 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 AJW70643.1 - 0.001 19.7 0.0 0.81 10.4 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJW70643.1 - 0.0027 17.7 0.0 1 9.5 0.0 3.2 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 AJW70643.1 - 0.0044 17.2 0.0 0.38 11.0 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Reprolysin_3 PF13582.6 AJW70643.1 - 0.006 17.1 1.7 0.011 16.2 0.2 2.2 3 0 0 3 3 2 1 Metallo-peptidase family M12B Reprolysin-like FAS_N PF17828.1 AJW70643.1 - 0.019 15.0 0.1 0.053 13.5 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta TPR_17 PF13431.6 AJW70643.1 - 0.042 14.2 0.0 14 6.4 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Reprolysin_2 PF13574.6 AJW70643.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 AJW70643.1 - 0.049 13.6 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Peptidase family M54 TPR_9 PF13371.6 AJW70643.1 - 0.06 13.5 0.0 1.3 9.2 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Reprolysin PF01421.19 AJW70643.1 - 0.088 12.7 0.2 0.18 11.7 0.2 1.6 1 1 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease MIT PF04212.18 AJW70643.1 - 0.17 12.0 1.0 12 6.1 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain NEAT PF05031.12 AJW70643.1 - 0.19 12.4 2.4 1.1 9.9 0.5 2.5 2 1 0 2 2 2 0 Iron Transport-associated domain AATF-Che1 PF13339.6 AJW70644.1 - 0.00046 20.9 2.4 0.00059 20.5 2.4 1.2 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DUF4037 PF13228.6 AJW70644.1 - 0.018 15.8 0.0 0.024 15.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) FapA PF03961.13 AJW70644.1 - 0.046 12.3 4.0 0.053 12.1 4.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cauli_DNA-bind PF03310.13 AJW70644.1 - 0.08 13.0 2.8 0.24 11.5 1.2 1.9 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein BPL_LplA_LipB PF03099.19 AJW70645.1 - 6.7e-18 64.9 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 AJW70645.1 - 5.6e-14 51.8 0.6 1.6e-13 50.4 0.2 2.1 2 0 0 2 2 2 1 HTH domain BPL_C PF02237.17 AJW70645.1 - 4.5e-07 29.7 0.8 8.8e-07 28.7 0.8 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain UPF0122 PF04297.14 AJW70645.1 - 0.014 15.6 1.2 0.049 13.9 0.1 2.3 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like PriA_3primeBD PF17764.1 AJW70645.1 - 0.024 14.5 0.0 0.072 13.0 0.0 1.8 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) Glyco_hyd_101C PF17451.2 AJW70645.1 - 0.11 12.7 0.6 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DUF4423 PF14394.6 AJW70646.1 - 0.00022 21.0 0.8 0.00031 20.5 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) TrmB PF01978.19 AJW70646.1 - 0.0012 18.6 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 AJW70646.1 - 0.0017 18.4 1.4 0.0027 17.8 1.0 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_45 PF14947.6 AJW70646.1 - 0.0022 18.0 0.3 0.0042 17.0 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix TFIIE_alpha PF02002.17 AJW70646.1 - 0.0047 16.8 0.5 0.0071 16.2 0.5 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit Rio2_N PF09202.11 AJW70646.1 - 0.0076 16.5 0.1 0.04 14.2 0.1 2.0 2 0 0 2 2 2 1 Rio2, N-terminal HTH_34 PF13601.6 AJW70646.1 - 0.0082 16.3 0.3 0.012 15.7 0.3 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Sulfolobus_pRN PF05584.11 AJW70646.1 - 0.018 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein DUF1676 PF07898.13 AJW70646.1 - 0.021 14.9 2.5 0.025 14.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) SARAF PF06682.12 AJW70646.1 - 0.03 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RelB_N PF18506.1 AJW70646.1 - 0.051 13.4 1.3 0.051 13.4 1.3 1.9 1 1 1 2 2 2 0 RelB Antitoxin alpha helical domain Rrf2 PF02082.20 AJW70646.1 - 0.075 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator APG17 PF04108.12 AJW70646.1 - 0.22 10.6 2.8 1.7 7.7 2.8 1.8 1 1 0 1 1 1 0 Autophagy protein Apg17 CoA_binding_2 PF13380.6 AJW70647.1 - 1.8e-37 128.4 0.1 2.1e-37 128.2 0.1 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AJW70647.1 - 1.7e-08 35.0 0.0 2.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_57 PF03065.15 AJW70647.1 - 0.018 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 MMR_HSR1_C PF08438.10 AJW70649.1 - 1.8e-31 109.0 0.0 4.3e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 AJW70649.1 - 6.6e-19 68.1 0.1 4e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 AJW70649.1 - 1.3e-07 31.5 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJW70649.1 - 2e-05 24.1 0.0 0.0008 19.0 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AJW70649.1 - 0.00097 19.2 0.2 0.19 11.7 0.0 3.0 2 1 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 AJW70649.1 - 0.078 12.5 0.8 9 5.8 0.2 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-FCS PF06467.14 AJW70650.1 - 0.0059 16.5 4.2 0.98 9.4 1.0 2.1 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.10 AJW70651.1 - 0.00036 20.2 3.8 0.00058 19.5 3.8 1.3 1 0 0 1 1 1 1 A2L zinc ribbon domain Tnp_zf-ribbon_2 PF13842.6 AJW70651.1 - 0.011 16.6 0.4 0.02 15.7 0.4 1.5 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon NRDD PF13597.6 AJW70651.1 - 0.016 14.1 0.3 0.017 14.0 0.3 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase UPF0547 PF10571.9 AJW70651.1 - 0.038 14.1 1.6 1.9 8.7 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 C1_2 PF03107.16 AJW70651.1 - 0.057 13.7 0.8 0.075 13.4 0.8 1.2 1 0 0 1 1 1 0 C1 domain DUF4108 PF13390.6 AJW70652.1 - 0.0086 16.0 0.5 0.011 15.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4108) Polyketide_cyc PF03364.20 AJW70653.1 - 0.013 15.7 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Amino_oxidase PF01593.24 AJW70654.1 - 1.8e-27 96.7 0.0 2.4e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AJW70654.1 - 9.6e-12 45.0 0.1 1.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AJW70654.1 - 3.5e-09 36.7 0.0 0.00095 18.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AJW70654.1 - 0.0001 21.2 0.0 0.14 10.8 0.4 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 AJW70654.1 - 0.00016 20.9 0.9 0.0057 15.8 1.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AJW70654.1 - 0.0002 20.7 0.7 0.076 12.2 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AJW70654.1 - 0.0005 19.4 0.4 0.00081 18.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AJW70654.1 - 0.0013 19.3 0.8 0.093 13.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AJW70654.1 - 0.022 13.9 1.9 0.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 AJW70654.1 - 0.042 13.1 0.4 0.072 12.3 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 AJW70654.1 - 0.23 10.7 3.3 0.71 9.1 0.3 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase B12-binding PF02310.19 AJW70655.1 - 3.7e-13 49.6 0.0 5.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AJW70655.1 - 8.9e-07 29.3 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain PcrB PF01884.17 AJW70655.1 - 0.021 14.3 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 PcrB family IPPT PF01715.17 AJW70655.1 - 0.023 14.5 0.0 0.07 12.9 0.0 1.8 2 0 0 2 2 2 0 IPP transferase ParG PF09274.10 AJW70656.1 - 0.14 12.3 0.1 2.3 8.4 0.1 2.4 1 1 2 3 3 3 0 ParG dCache_2 PF08269.11 AJW70657.1 - 0.027 13.6 0.1 0.035 13.3 0.1 1.1 1 0 0 1 1 1 0 Cache domain CpxA_peri PF16527.5 AJW70657.1 - 0.055 13.8 0.1 8.6 6.7 0.0 2.1 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain DICT PF10069.9 AJW70658.1 - 0.0031 17.3 0.1 0.032 14.0 0.0 2.0 2 0 0 2 2 2 1 Sensory domain in DIguanylate Cyclases and Two-component system FAD_binding_7 PF03441.14 AJW70659.1 - 8.5e-77 257.2 2.1 1.3e-76 256.6 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AJW70659.1 - 2.7e-35 121.8 0.0 4.3e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase MinC_C PF03775.16 AJW70660.1 - 0.062 13.3 0.0 0.07 13.1 0.0 1.1 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain TIR_3 PF18567.1 AJW70660.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain NAD_binding_10 PF13460.6 AJW70662.1 - 1.8e-12 47.5 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AJW70662.1 - 5.6e-12 45.7 0.0 8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 AJW70662.1 - 6.2e-12 45.5 0.0 2.8e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJW70662.1 - 4.4e-10 39.0 0.0 7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AJW70662.1 - 0.00036 20.0 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AJW70662.1 - 0.0093 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AJW70662.1 - 0.089 11.9 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein TetR_C_23 PF17931.1 AJW70662.1 - 0.11 12.6 1.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Polysacc_synt_2 PF02719.15 AJW70662.1 - 0.15 11.1 1.0 1.5 7.9 1.0 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2OG-FeII_Oxy_3 PF13640.6 AJW70665.1 - 3.7e-05 24.5 0.0 5.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily JmjC PF02373.22 AJW70665.1 - 0.014 15.9 0.1 0.068 13.6 0.0 2.0 2 0 0 2 2 2 0 JmjC domain, hydroxylase COR PF16095.5 AJW70665.1 - 0.039 13.8 0.3 8 6.2 0.0 2.2 1 1 0 2 2 2 0 C-terminal of Roc, COR, domain PhyH PF05721.13 AJW70665.1 - 0.044 14.0 0.0 0.093 13.0 0.0 1.5 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Peripla_BP_2 PF01497.18 AJW70666.1 - 2.2e-18 66.7 0.0 4e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein Ribosomal_L17 PF01196.19 AJW70666.1 - 0.022 15.6 0.0 0.047 14.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L17 GED PF02212.18 AJW70666.1 - 0.037 14.2 1.9 0.092 12.9 1.9 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain DUF5398 PF17376.2 AJW70666.1 - 0.042 14.5 1.4 0.095 13.3 1.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5398) NAPRTase_C PF17956.1 AJW70666.1 - 0.051 14.0 0.8 0.12 12.8 0.7 1.7 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain Nre_N PF04894.12 AJW70667.1 - 3.6e-91 305.7 0.0 5.5e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 AJW70667.1 - 2.5e-32 111.0 0.0 4e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal Nre, C-terminal Toxin_trans PF07952.12 AJW70667.1 - 0.031 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain HTH_7 PF02796.15 AJW70667.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF1722 PF08349.11 AJW70668.1 - 2.5e-32 111.6 2.4 4.1e-32 110.9 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) CRISPR_Cas9_WED PF18061.1 AJW70668.1 - 0.0074 16.4 2.3 0.0074 16.4 2.3 1.9 2 1 0 2 2 2 1 CRISPR-Cas9 WED domain DUF1002 PF06207.11 AJW70668.1 - 0.027 14.0 1.2 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) DUF432 PF04254.13 AJW70671.1 - 6.1e-30 103.9 0.0 1.1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF432) MS_channel PF00924.18 AJW70672.1 - 3.8e-46 157.2 0.4 5.8e-46 156.6 0.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel FeoB_associated PF12669.7 AJW70673.1 - 0.5 10.8 2.6 3.9 7.9 0.4 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Insulin_TMD PF17870.1 AJW70673.1 - 2.4 8.3 6.3 2.4 8.3 0.3 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF740 PF05340.12 AJW70675.1 - 0.033 12.9 0.0 0.035 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Putative_PNPOx PF01243.20 AJW70676.1 - 2.4e-06 27.7 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJW70676.1 - 0.0073 16.3 0.0 0.0095 15.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase tRNA-synt_1e PF01406.19 AJW70678.1 - 1.9e-125 418.2 1.1 1.9e-125 418.2 1.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AJW70678.1 - 5.5e-11 41.9 1.7 8.5e-06 24.8 0.9 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 AJW70678.1 - 8.6e-11 42.2 1.5 8.6e-11 42.2 1.5 1.8 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.18 AJW70678.1 - 2.2e-07 30.1 0.2 0.0024 16.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 AJW70678.1 - 3.6e-06 25.5 0.0 1.3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Rep_fac_C PF08542.11 AJW70678.1 - 0.076 13.4 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF1447 PF07288.11 AJW70678.1 - 0.78 9.8 5.7 23 5.2 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1447) NAD_synthase PF02540.17 AJW70679.1 - 9.3e-77 257.4 0.2 1.1e-76 257.2 0.2 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 AJW70679.1 - 0.00012 21.1 0.0 0.0022 16.9 0.0 2.2 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 AJW70679.1 - 0.0018 17.8 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AJW70679.1 - 0.0065 16.2 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.14 AJW70679.1 - 0.0094 15.5 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 AJW70679.1 - 0.029 14.0 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase eRF1_2 PF03464.15 AJW70679.1 - 0.05 13.9 0.1 0.09 13.1 0.1 1.3 1 0 0 1 1 1 0 eRF1 domain 2 HTH_5 PF01022.20 AJW70679.1 - 0.11 12.3 0.1 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4_2 PF08281.12 AJW70679.1 - 0.16 11.7 0.2 3.1 7.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-70, region 4 sCache_3_2 PF17203.4 AJW70680.1 - 0.051 13.7 0.2 23 5.1 0.0 2.9 2 1 1 3 3 3 0 Single cache domain 3 Rieske PF00355.26 AJW70681.1 - 1.1e-14 54.1 0.0 1.3e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJW70681.1 - 3.5e-12 46.2 0.0 4.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain AdoHcyase_NAD PF00670.21 AJW70682.1 - 7.4e-52 175.7 0.9 7.4e-52 175.7 0.9 2.0 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 AJW70682.1 - 1.8e-51 175.1 0.0 6.3e-25 87.9 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 AJW70682.1 - 1.1e-09 37.9 0.8 1.8e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AJW70682.1 - 4.5e-07 29.6 0.1 9.6e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AJW70682.1 - 0.0004 20.6 0.0 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 AJW70682.1 - 0.0051 16.9 1.7 0.054 13.6 0.1 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AJW70682.1 - 0.0059 17.2 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AJW70682.1 - 0.0091 15.9 1.4 0.025 14.4 0.3 2.3 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AJW70682.1 - 0.017 14.7 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 AJW70682.1 - 0.039 13.3 2.6 0.32 10.2 2.6 2.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AJW70682.1 - 0.055 12.7 0.2 0.28 10.4 0.1 1.8 1 1 2 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJW70682.1 - 0.061 13.9 1.1 0.18 12.3 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1g PF09334.11 AJW70683.1 - 1.2e-140 468.7 1.4 1.4e-140 468.5 1.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AJW70683.1 - 1.2e-18 66.7 0.7 1.1e-06 27.3 0.0 4.1 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AJW70683.1 - 1.3e-13 51.0 0.3 1.4e-06 27.9 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 AJW70683.1 - 1.3e-08 35.0 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 AJW70683.1 - 1.7e-06 27.2 0.1 0.0012 17.8 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (K) FhuF PF06276.12 AJW70683.1 - 0.016 15.7 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Lge1 PF11488.8 AJW70683.1 - 0.064 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Trans_coact PF16805.5 AJW70683.1 - 0.094 12.8 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Phage late-transcription coactivator DZR PF12773.7 AJW70683.1 - 0.78 9.8 7.0 1.6 8.8 7.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 AJW70683.1 - 1.4 9.3 4.6 3.3 8.1 4.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.12 AJW70683.1 - 6.1 6.5 6.9 2 8.0 2.7 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 AJW70683.1 - 7.1 6.7 5.4 16 5.6 1.2 2.5 2 1 1 3 3 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF726 PF05277.12 AJW70684.1 - 3.3e-10 39.4 0.0 4.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 AJW70684.1 - 7.7e-08 32.1 0.0 1.4e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 AJW70684.1 - 0.00015 21.3 0.6 0.0066 16.0 0.6 2.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 AJW70684.1 - 0.0018 17.5 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 AJW70684.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 AJW70684.1 - 0.0059 16.2 0.1 0.0076 15.8 0.1 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF1749 PF08538.10 AJW70684.1 - 0.007 15.5 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 AJW70684.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 AJW70684.1 - 0.022 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_2 PF02230.16 AJW70684.1 - 0.068 13.0 0.5 0.13 12.1 0.2 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ribos_L4_asso_C PF14374.6 AJW70684.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain Abhydrolase_8 PF06259.12 AJW70684.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase Guanylate_cyc PF00211.20 AJW70685.1 - 0.0002 21.0 0.0 0.0005 19.7 0.0 1.7 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 AJW70686.1 - 3.4e-14 52.9 0.0 4.4e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HYR PF02494.16 AJW70688.1 - 0.17 12.2 4.0 5.7 7.4 0.1 3.6 3 1 0 3 3 3 0 HYR domain Peptidase_M10 PF00413.24 AJW70689.1 - 1.1e-12 48.1 0.5 1.6e-12 47.5 0.5 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 AJW70689.1 - 0.022 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.24 AJW70689.1 - 0.04 13.5 0.3 8.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 AJW70689.1 - 0.15 12.6 0.3 0.29 11.7 0.3 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 AJW70690.1 - 0.00056 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AJW70690.1 - 0.0013 18.9 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 AJW70690.1 - 0.0015 17.5 0.6 0.0015 17.5 0.6 1.9 2 1 0 2 2 2 1 Peptidase M66 Reprolysin_3 PF13582.6 AJW70690.1 - 0.0021 18.6 0.3 0.0054 17.3 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 AJW70690.1 - 0.038 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Matrixin Reprolysin PF01421.19 AJW70690.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Astacin PF01400.24 AJW70690.1 - 0.14 11.8 0.1 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) ADAM17_MPD PF16698.5 AJW70690.1 - 1.1 9.7 4.5 3.3 8.2 4.5 1.8 1 0 0 1 1 1 0 Membrane-proximal domain, switch, for ADAM17 Clusterin PF01093.17 AJW70691.1 - 0.27 10.3 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Clusterin TBP PF00352.21 AJW70692.1 - 1.4e-50 169.2 0.1 1.6e-24 85.7 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJW70692.1 - 2.3e-06 27.6 0.0 0.018 15.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) TFIIB PF00382.19 AJW70693.1 - 1.7e-34 117.7 3.1 3.1e-17 62.4 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW70693.1 - 2.3e-10 39.8 0.7 4.1e-10 39.0 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 AJW70693.1 - 0.00033 20.7 0.0 0.5 10.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 AJW70693.1 - 0.00095 18.6 0.1 0.053 13.0 0.0 3.0 4 0 0 4 4 4 1 Sigma-70, region 4 RB_B PF01857.20 AJW70693.1 - 0.0028 17.7 0.1 0.0079 16.2 0.0 1.7 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF294_C PF10335.9 AJW70693.1 - 0.0054 16.5 0.3 3.5 7.4 0.1 2.2 2 0 0 2 2 2 2 Putative nucleotidyltransferase substrate binding domain Cyclin_N PF00134.23 AJW70693.1 - 0.0091 15.7 0.1 0.041 13.6 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_L37e PF01907.19 AJW70693.1 - 0.0096 16.1 0.2 0.026 14.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L37e zinc_ribbon_2 PF13240.6 AJW70693.1 - 0.016 14.9 1.7 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Sigma70_r4_2 PF08281.12 AJW70693.1 - 0.022 14.4 0.9 0.42 10.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 DZR PF12773.7 AJW70693.1 - 0.032 14.3 0.4 0.083 12.9 0.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon HTH_11 PF08279.12 AJW70693.1 - 0.047 13.7 2.1 0.98 9.4 0.0 3.1 3 0 0 3 3 3 0 HTH domain HypA PF01155.19 AJW70693.1 - 0.057 13.4 0.8 0.14 12.2 0.2 1.9 2 0 0 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HTH_23 PF13384.6 AJW70693.1 - 0.06 13.2 0.2 2.4 8.0 0.0 2.8 2 1 0 2 2 2 0 Homeodomain-like domain RPW8 PF05659.11 AJW70693.1 - 0.095 12.4 0.3 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 HTH_AsnC-type PF13404.6 AJW70693.1 - 0.098 12.5 0.1 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zf-ribbon_3 PF13248.6 AJW70693.1 - 0.12 11.9 0.8 3.8 7.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Phage_terminase PF10668.9 AJW70693.1 - 0.2 11.7 2.2 5.3 7.1 0.0 3.4 4 0 0 4 4 4 0 Phage terminase small subunit zf_UBZ PF18439.1 AJW70693.1 - 0.21 11.2 1.1 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 AJW70693.1 - 1.6 8.4 4.1 18 5.1 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GTP_EFTU_D2 PF03144.25 AJW70694.1 - 2.3e-07 31.1 0.1 6.7e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 eIF2_C PF09173.11 AJW70694.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal Dict-STAT-coil PF09267.10 AJW70694.1 - 0.15 12.5 0.0 0.48 10.8 0.0 1.8 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil CTP_transf_like PF01467.26 AJW70695.1 - 3.2e-14 53.3 0.0 4.3e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 AJW70695.1 - 0.00048 19.5 0.0 0.23 10.6 0.0 2.1 2 0 0 2 2 2 2 HIGH Nucleotidyl Transferase Citrate_ly_lig PF08218.11 AJW70695.1 - 0.0016 18.1 0.0 0.17 11.6 0.0 2.2 1 1 1 2 2 2 2 Citrate lyase ligase C-terminal domain FAD_syn PF06574.12 AJW70695.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase IlvN PF07991.12 AJW70696.1 - 6.4e-66 221.0 0.5 8.8e-66 220.5 0.5 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AJW70696.1 - 1.6e-55 187.3 1.8 2.5e-55 186.7 1.8 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AJW70696.1 - 8.2e-06 25.3 0.1 1.4e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AJW70696.1 - 0.003 17.7 0.4 0.021 15.0 0.1 2.3 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AJW70696.1 - 0.0053 17.3 0.2 0.012 16.2 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AJW70696.1 - 0.0091 16.1 0.2 0.018 15.1 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4085 PF13315.6 AJW70696.1 - 0.073 12.7 0.4 0.13 11.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) B12-binding PF02310.19 AJW70697.1 - 6.5e-23 81.1 0.2 7.3e-23 80.9 0.2 1.0 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 AJW70697.1 - 0.0047 16.0 0.1 0.0055 15.7 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DnaJ_CXXCXGXG PF00684.19 AJW70698.1 - 0.0015 18.8 8.6 0.0031 17.8 8.7 1.5 1 1 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 AJW70698.1 - 0.059 13.6 9.6 0.11 12.7 4.5 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 AJW70698.1 - 0.44 10.5 8.2 1.8 8.6 2.4 3.0 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-nanos PF05741.13 AJW70698.1 - 2.7 8.3 12.4 1.3e+02 2.9 12.4 2.7 1 1 0 1 1 1 0 Nanos RNA binding domain zinc_ribbon_6 PF14599.6 AJW70699.1 - 0.0076 16.2 3.0 0.015 15.3 3.0 1.6 1 1 0 1 1 1 1 Zinc-ribbon Apidaecin PF00807.17 AJW70699.1 - 0.046 13.8 0.2 0.054 13.6 0.2 1.2 1 0 0 1 1 1 0 Apidaecin Zn-ribbon_8 PF09723.10 AJW70699.1 - 0.12 12.5 6.2 0.18 12.0 6.2 1.3 1 0 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 AJW70699.1 - 0.15 12.0 3.0 0.18 11.8 3.0 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Alba PF01918.21 AJW70700.1 - 6.5e-10 38.7 0.2 8.8e-10 38.3 0.2 1.2 1 0 0 1 1 1 1 Alba TFIIB PF00382.19 AJW70701.1 - 3.4e-32 110.3 5.2 4.4e-17 61.9 0.7 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW70701.1 - 9e-10 37.9 0.8 1.5e-09 37.2 0.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_AsnC-type PF13404.6 AJW70701.1 - 0.00031 20.5 0.0 0.0084 15.9 0.0 2.8 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain Cyclin_N PF00134.23 AJW70701.1 - 0.00047 19.9 0.5 0.039 13.7 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_11 PF08279.12 AJW70701.1 - 0.0028 17.6 0.7 0.13 12.2 0.0 3.1 3 0 0 3 3 3 1 HTH domain HTH_Crp_2 PF13545.6 AJW70701.1 - 0.0048 16.8 0.1 0.5 10.4 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain RB_B PF01857.20 AJW70701.1 - 0.011 15.7 0.2 0.028 14.5 0.2 1.7 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain Sigma70_r4 PF04545.16 AJW70701.1 - 0.011 15.2 0.1 4.9 6.8 0.0 3.1 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_3 PF01381.22 AJW70701.1 - 0.023 14.8 0.1 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix Cyclin_C PF02984.19 AJW70701.1 - 0.045 13.8 0.1 7.7 6.6 0.0 2.3 1 1 1 2 2 2 0 Cyclin, C-terminal domain TetR_N PF00440.23 AJW70701.1 - 0.051 13.4 0.1 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Ribosomal_L37e PF01907.19 AJW70701.1 - 0.055 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L37e LacI PF00356.21 AJW70701.1 - 0.062 13.1 3.2 7.6 6.4 0.1 3.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Rrf2 PF02082.20 AJW70701.1 - 0.076 13.4 0.5 22 5.5 0.0 3.4 3 1 1 4 4 4 0 Transcriptional regulator HTH_24 PF13412.6 AJW70701.1 - 0.11 12.0 0.3 2.5 7.7 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding zf_UBZ PF18439.1 AJW70701.1 - 0.18 11.4 0.4 10 5.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 AJW70701.1 - 0.2 11.4 3.5 0.12 12.1 1.5 1.7 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.6 AJW70701.1 - 0.34 10.7 2.2 1.2 8.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TrmB PF01978.19 AJW70702.1 - 0.00088 19.1 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FUR PF01475.19 AJW70702.1 - 0.0014 18.7 0.1 0.0017 18.5 0.1 1.3 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_24 PF13412.6 AJW70702.1 - 0.0051 16.3 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AJW70702.1 - 0.011 15.5 0.1 0.02 14.7 0.1 1.6 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.7 AJW70702.1 - 0.05 13.7 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AJW70702.1 - 0.22 11.4 1.4 0.27 11.2 0.3 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family CopG_antitoxin PF12441.8 AJW70703.1 - 0.00024 21.6 0.2 0.00053 20.5 0.2 1.6 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system Dna2 PF08696.11 AJW70703.1 - 0.0054 16.6 0.6 0.32 10.8 0.2 2.1 2 0 0 2 2 2 2 DNA replication factor Dna2 Pox_EPC_I2-L1 PF12575.8 AJW70703.1 - 0.029 14.6 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF5101 PF17031.5 AJW70703.1 - 0.073 13.2 0.7 0.79 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) HicB PF05534.12 AJW70703.1 - 0.082 12.8 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 HicB family NinF PF05810.12 AJW70704.1 - 0.012 15.4 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 0 NinF protein zf-FCS PF06467.14 AJW70704.1 - 0.19 11.7 4.6 0.69 9.9 0.4 2.2 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Peptidase_M1 PF01433.20 AJW70705.1 - 1.5e-89 299.3 0.8 1.5e-89 299.3 0.8 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 AJW70705.1 - 1.5e-62 212.0 0.2 1.3e-61 208.9 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 AJW70705.1 - 7.6e-55 186.0 2.1 1.6e-54 185.0 2.1 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 AJW70705.1 - 0.0065 15.9 0.5 0.031 13.6 0.1 2.1 2 0 0 2 2 2 1 Putative aminopeptidase UB2H PF14814.6 AJW70705.1 - 0.11 12.6 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain MeaB PF03308.16 AJW70707.1 - 1.2e-69 234.3 4.7 1.5e-69 234.0 4.7 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AJW70707.1 - 2.1e-06 27.5 0.1 2.1e-06 27.5 0.1 2.0 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AJW70707.1 - 4.3e-05 23.4 0.3 0.0075 16.1 0.1 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.14 AJW70707.1 - 5e-05 22.7 5.7 0.00015 21.1 4.5 2.2 1 1 1 2 2 2 1 KAP family P-loop domain RsgA_GTPase PF03193.16 AJW70707.1 - 0.00021 21.3 0.6 0.0031 17.4 0.1 2.5 2 1 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 AJW70707.1 - 0.00022 20.5 1.9 0.003 16.8 0.3 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 AJW70707.1 - 0.0063 16.3 2.2 0.15 11.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain Ubiq_cyt_C_chap PF03981.12 AJW70707.1 - 0.011 15.8 0.5 0.022 14.8 0.5 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone ATPase_2 PF01637.18 AJW70707.1 - 0.017 15.0 3.8 0.041 13.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Spore_IV_A PF09547.10 AJW70707.1 - 0.018 14.0 3.8 0.018 14.0 0.2 2.0 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) AAA_30 PF13604.6 AJW70707.1 - 0.023 14.4 0.4 0.041 13.6 0.4 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AJW70707.1 - 0.028 14.5 3.7 0.16 12.0 3.7 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fibin PF15819.5 AJW70707.1 - 0.028 14.2 0.2 0.049 13.4 0.2 1.4 1 0 0 1 1 1 0 Fin bud initiation factor homologue AAA_16 PF13191.6 AJW70707.1 - 0.032 14.6 0.1 0.064 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 AJW70707.1 - 0.034 13.6 0.2 0.034 13.6 0.2 2.0 2 1 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 AJW70707.1 - 0.035 13.4 0.2 0.075 12.3 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin IIGP PF05049.13 AJW70707.1 - 0.04 13.0 0.8 0.04 13.0 0.8 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 AJW70707.1 - 0.045 14.2 9.5 0.98 9.9 0.6 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AJW70707.1 - 0.06 13.2 1.9 0.093 12.6 0.3 2.1 2 1 0 2 2 2 0 NTPase AAA_35 PF14516.6 AJW70707.1 - 0.088 11.6 1.2 0.13 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.27 AJW70707.1 - 0.092 13.3 3.9 0.11 13.0 0.6 2.3 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 AJW70707.1 - 0.12 12.1 0.4 0.28 11.0 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 AJW70707.1 - 0.12 12.0 3.1 0.18 11.5 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 AJW70707.1 - 0.14 12.5 0.3 0.42 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AJW70707.1 - 0.19 12.1 1.1 0.34 11.2 1.1 1.8 1 1 0 1 1 1 0 AAA domain MM_CoA_mutase PF01642.22 AJW70708.1 - 3e-213 709.0 0.3 3.4e-213 708.8 0.3 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase HigB_toxin PF09907.9 AJW70708.1 - 0.099 12.9 0.8 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system Methyltransf_23 PF13489.6 AJW70709.1 - 0.0002 21.3 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW70709.1 - 0.0056 17.4 0.0 0.015 16.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJW70709.1 - 0.03 14.1 0.2 0.11 12.3 0.2 1.9 2 1 0 2 2 2 0 Methyltransferase domain Glyoxalase_4 PF13669.6 AJW70711.1 - 2e-23 82.7 0.0 2.3e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AJW70711.1 - 1.8e-13 50.8 0.0 2e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AJW70711.1 - 1.1e-10 42.0 0.0 1.1e-10 41.9 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AJW70711.1 - 0.00039 21.2 0.0 0.00048 20.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain YecM PF06185.12 AJW70711.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 YecM protein zf-C4_ClpX PF06689.13 AJW70712.1 - 0.00047 20.0 0.8 0.00047 20.0 0.8 2.4 2 1 0 2 2 2 1 ClpX C4-type zinc finger DUF2039 PF10217.9 AJW70712.1 - 0.011 16.0 11.2 0.029 14.7 5.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) C1_2 PF03107.16 AJW70712.1 - 0.023 15.0 2.6 0.023 15.0 2.6 3.0 2 1 1 3 3 3 0 C1 domain DZR PF12773.7 AJW70712.1 - 0.038 14.0 8.5 2 8.5 8.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.6 AJW70712.1 - 0.046 14.1 8.4 0.13 12.6 0.6 2.7 3 0 0 3 3 3 0 Ring finger domain zf-RING_11 PF17123.5 AJW70712.1 - 0.058 13.2 8.0 1.7 8.5 0.5 2.4 2 0 0 2 2 2 0 RING-like zinc finger UPF0167 PF03691.14 AJW70712.1 - 0.063 13.1 10.0 0.056 13.2 2.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) LIM PF00412.22 AJW70712.1 - 0.17 12.1 9.5 0.57 10.5 1.3 2.8 1 1 1 2 2 2 0 LIM domain Prok-RING_1 PF14446.6 AJW70712.1 - 0.17 11.8 11.2 0.17 11.8 0.8 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.6 AJW70712.1 - 0.3 10.9 9.6 0.32 10.8 0.8 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-UDP PF14569.6 AJW70712.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.8 3 1 0 3 3 3 0 Zinc-binding RING-finger zf_UBZ PF18439.1 AJW70712.1 - 0.32 10.6 14.4 2.7 7.7 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_2 PF13923.6 AJW70712.1 - 0.39 10.6 13.2 0.57 10.1 0.6 3.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.14 AJW70712.1 - 0.42 10.6 5.1 1.3 9.1 0.5 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid C1_1 PF00130.22 AJW70712.1 - 0.62 10.0 12.1 1.7 8.6 1.5 3.0 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.12 AJW70712.1 - 0.7 10.4 10.6 2.6 8.6 10.5 2.0 1 1 0 1 1 1 0 CHY zinc finger Ribosomal_L37e PF01907.19 AJW70712.1 - 2.3 8.4 9.9 0.15 12.3 1.0 2.5 1 1 1 2 2 2 0 Ribosomal protein L37e DUF2256 PF10013.9 AJW70712.1 - 4.8 7.4 11.1 6.6 6.9 0.3 3.5 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_3 PF13920.6 AJW70712.1 - 5.9 6.8 14.1 14 5.7 0.5 2.9 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CBS PF00571.28 AJW70713.1 - 1.8e-14 53.9 0.5 4.7e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 CBS domain HTH_3 PF01381.22 AJW70713.1 - 3.7e-14 52.5 0.3 6.6e-14 51.7 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AJW70713.1 - 8e-09 35.4 0.2 2e-08 34.1 0.2 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AJW70713.1 - 9.1e-07 29.1 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AJW70713.1 - 0.0025 17.9 0.0 0.0053 16.9 0.0 1.5 2 0 0 2 2 2 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_25 PF13413.6 AJW70713.1 - 0.0027 17.5 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AJW70713.1 - 0.032 14.2 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_M99_m PF17130.4 AJW70713.1 - 0.068 13.1 0.1 0.26 11.2 0.0 1.9 2 1 0 2 2 2 0 beta-barrel domain of carboxypeptidase M99 HTH_24 PF13412.6 AJW70713.1 - 0.068 12.7 0.1 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 AJW70713.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4 PF04545.16 AJW70713.1 - 0.16 11.5 0.2 0.35 10.4 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1059 PF06348.11 AJW70714.1 - 5.2e-18 65.0 0.3 5.8e-18 64.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Sina PF03145.16 AJW70714.1 - 0.082 12.9 0.1 0.09 12.7 0.1 1.1 1 0 0 1 1 1 0 Seven in absentia protein family JmjC PF02373.22 AJW70714.1 - 0.098 13.1 0.1 0.1 13.0 0.1 1.0 1 0 0 1 1 1 0 JmjC domain, hydroxylase PEP-utilizers_C PF02896.18 AJW70715.1 - 1e-84 284.1 0.3 2e-84 283.2 0.3 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AJW70715.1 - 3.4e-57 194.2 0.0 7e-34 117.6 0.0 3.4 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AJW70715.1 - 1.8e-24 85.3 0.0 4.5e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain COE1_HLH PF16423.5 AJW70715.1 - 0.016 14.9 0.0 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain DUF968 PF06147.11 AJW70715.1 - 0.047 13.9 0.2 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF968) XRN1_D1 PF18332.1 AJW70715.1 - 0.45 10.2 2.4 6.3 6.5 0.1 2.9 3 0 0 3 3 3 0 Exoribonuclease Xrn1 D1 domain NUC PF18510.1 AJW70715.1 - 0.73 10.3 3.3 0.44 11.0 0.4 2.1 2 0 0 2 2 2 0 Nuclease domain TIM PF00121.18 AJW70716.1 - 1.6e-09 37.5 4.1 7.2e-09 35.4 0.3 2.0 1 1 1 2 2 2 2 Triosephosphate isomerase ThiG PF05690.14 AJW70716.1 - 1e-05 25.0 0.1 1.6e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 AJW70716.1 - 0.00071 18.7 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IGPS PF00218.21 AJW70716.1 - 0.0025 17.0 0.2 0.0042 16.3 0.2 1.4 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 AJW70716.1 - 0.031 13.7 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase Synuclein PF01387.17 AJW70716.1 - 0.062 13.5 0.2 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 Synuclein MtN3_slv PF03083.16 AJW70717.1 - 1.1e-08 35.0 3.1 1.2e-08 34.8 3.1 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 AJW70717.1 - 0.0014 18.4 2.8 0.0025 17.5 2.8 1.5 1 0 0 1 1 1 1 PQ loop repeat LAB_N PF07578.11 AJW70717.1 - 0.0076 16.3 3.1 0.0098 16.0 3.1 1.2 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain DUF3784 PF12650.7 AJW70717.1 - 5.5 7.3 12.3 18 5.6 12.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DNA_pol_B PF00136.21 AJW70718.1 - 8.2e-56 189.6 5.9 1.4e-55 188.8 5.9 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 AJW70718.1 - 1.8e-39 135.9 6.7 3.2e-39 135.0 6.7 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 AJW70718.1 - 4.3e-07 30.1 0.7 1.1e-06 28.7 0.7 1.7 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 AJW70718.1 - 1.7e-05 24.6 0.6 5.4e-05 23.0 0.6 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Rep_fac-A_C PF08646.10 AJW70718.1 - 0.0071 16.1 1.2 0.25 11.1 0.2 2.7 2 0 0 2 2 2 1 Replication factor-A C terminal domain dCMP_cyt_deam_1 PF00383.23 AJW70719.1 - 2.2e-27 94.9 1.3 2.8e-27 94.5 1.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AJW70719.1 - 3.7e-14 52.6 0.2 4.8e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 MafB19-like deaminase ResIII PF04851.15 AJW70721.1 - 8.9e-20 71.4 0.0 1.6e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJW70721.1 - 1.4e-18 67.2 0.0 4.1e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 AJW70721.1 - 0.0084 16.1 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 1 Flavivirus DEAD domain Helicase_C PF00271.31 AJW70721.1 - 0.05 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF3638 PF12340.8 AJW70721.1 - 0.081 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) SWI2_SNF2 PF18766.1 AJW70721.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF4320 PF14208.6 AJW70722.1 - 0.019 15.0 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) SapB_1 PF05184.15 AJW70722.1 - 0.12 12.4 1.6 0.37 10.9 0.3 2.5 2 1 1 3 3 3 0 Saposin-like type B, region 1 AAA_lid_10 PF17872.1 AJW70723.1 - 0.038 14.1 0.7 0.041 14.0 0.7 1.0 1 0 0 1 1 1 0 AAA lid domain Rotamase_3 PF13616.6 AJW70724.1 - 3.1e-25 89.0 0.3 5.2e-25 88.3 0.3 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AJW70724.1 - 1.4e-23 83.7 0.1 1.7e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AJW70724.1 - 1.6e-08 35.4 0.0 1.9e-08 35.2 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain NTPase_I-T PF01931.18 AJW70724.1 - 0.0024 17.7 0.0 0.0032 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF84 NitrOD1 PF18549.1 AJW70725.1 - 8.2e-05 22.5 0.0 9.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Nitrosopumilus output domain 1 EamA PF00892.20 AJW70726.1 - 3.8e-32 111.3 33.5 2.8e-16 60.0 7.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 AJW70726.1 - 1.9e-06 27.4 26.1 4.1e-06 26.3 6.2 2.8 1 1 2 3 3 3 2 Purine nucleobase transmembrane transport SLC35F PF06027.12 AJW70726.1 - 2.4e-06 27.3 20.5 3.2e-06 26.9 20.5 1.3 1 0 0 1 1 1 1 Solute carrier family 35 TPT PF03151.16 AJW70726.1 - 2.1e-05 24.0 25.5 0.0001 21.7 25.5 2.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family Acyl_transf_3 PF01757.22 AJW70726.1 - 0.0017 17.5 19.5 0.014 14.5 11.6 2.6 2 1 1 3 3 3 2 Acyltransferase family TMEM234 PF10639.9 AJW70726.1 - 0.003 17.6 0.5 0.003 17.6 0.5 3.2 3 1 0 3 3 3 1 Putative transmembrane family 234 HEAT_2 PF13646.6 AJW70727.1 - 1.4e-10 41.4 0.6 5.8e-10 39.4 0.4 1.8 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.22 AJW70727.1 - 0.00012 22.1 0.3 4.1 7.9 0.0 3.5 3 0 0 3 3 3 3 HEAT repeat Cnd1 PF12717.7 AJW70727.1 - 0.011 15.8 0.2 0.039 14.0 0.2 2.1 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF1129 PF06570.11 AJW70728.1 - 8.8 5.8 10.8 6.5 6.2 8.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) TrmB PF01978.19 AJW70729.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Response_reg PF00072.24 AJW70730.1 - 3.2e-24 85.2 0.5 3.7e-24 85.1 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain AAA_14 PF13173.6 AJW70730.1 - 0.072 13.1 0.1 0.09 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain Putative_PNPOx PF01243.20 AJW70731.1 - 2.2e-11 43.8 0.0 2.7e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJW70731.1 - 6.5e-06 26.2 0.0 7.5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AJW70731.1 - 0.00012 21.7 0.1 0.00013 21.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like DUF447 PF04289.12 AJW70731.1 - 0.038 13.8 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Spore_YhcN_YlaJ PF09580.10 AJW70731.1 - 0.064 13.3 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Syntaxin_2 PF14523.6 AJW70732.1 - 0.062 13.7 0.0 0.99 9.8 0.0 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF2203 PF09969.9 AJW70733.1 - 2e-36 125.4 0.1 2.3e-36 125.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) GCR1_C PF12550.8 AJW70733.1 - 0.041 14.2 1.1 0.084 13.2 0.1 1.9 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes His_binding PF02098.16 AJW70733.1 - 0.053 13.6 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Tick histamine binding protein TrmB PF01978.19 AJW70734.1 - 2.1e-13 50.0 0.0 5.5e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AJW70734.1 - 1.7e-06 27.8 0.2 3.7e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AJW70734.1 - 0.00018 21.4 0.2 0.00049 20.0 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AJW70734.1 - 0.00058 19.9 0.1 0.0013 18.8 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AJW70734.1 - 0.018 14.6 0.2 0.035 13.7 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Regulator_TrmB PF11495.8 AJW70734.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Beta_protein PF14350.6 AJW70734.1 - 0.048 13.1 0.1 0.065 12.6 0.1 1.1 1 0 0 1 1 1 0 Beta protein DIMCO_N PF16844.5 AJW70734.1 - 0.09 13.1 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal HTH_29 PF13551.6 AJW70734.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_11 PF08279.12 AJW70734.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.6 3 0 0 3 3 3 0 HTH domain DUF1515 PF07439.11 AJW70734.1 - 0.28 11.2 1.2 12 5.9 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) T2SSF PF00482.23 AJW70735.1 - 3.3e-18 65.8 0.3 8.1e-18 64.6 0.3 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F DDE_Tnp_1_assoc PF13808.6 AJW70735.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-associated MtrG PF04210.13 AJW70735.1 - 0.19 11.6 2.8 0.44 10.4 0.0 2.8 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1129 PF06570.11 AJW70735.1 - 0.34 10.4 4.8 0.36 10.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) T2SSF PF00482.23 AJW70736.1 - 1.8e-14 53.8 0.3 1.8e-14 53.8 0.3 2.6 3 1 1 4 4 4 1 Type II secretion system (T2SS), protein F DUF1772 PF08592.11 AJW70736.1 - 0.071 13.4 2.5 0.84 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) TackOD1 PF18551.1 AJW70737.1 - 6.1e-27 94.5 5.6 8.4e-27 94.1 5.6 1.2 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 Zn-ribbon_8 PF09723.10 AJW70737.1 - 0.011 15.8 8.6 1.3 9.2 0.1 3.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-LYAR PF08790.11 AJW70737.1 - 0.046 13.6 1.0 0.14 12.1 1.0 1.9 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 AJW70737.1 - 0.3 11.0 2.6 30 4.6 0.1 3.4 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Cys_rich_KTR PF14205.6 AJW70737.1 - 0.42 10.4 4.4 0.34 10.7 0.2 2.8 3 0 0 3 3 3 0 Cysteine-rich KTR Zn_Tnp_IS1 PF03811.13 AJW70737.1 - 1.6 8.5 5.8 0.79 9.5 0.2 2.7 2 0 0 2 2 2 0 InsA N-terminal domain DZR PF12773.7 AJW70737.1 - 1.9 8.6 5.6 9.1 6.4 5.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 AJW70737.1 - 3.8 7.6 5.2 24 5.0 0.9 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 AJW70737.1 - 5.5 7.0 8.0 15 5.7 2.2 2.6 1 1 2 3 3 3 0 zinc-ribbons DUF3272 PF11676.8 AJW70739.1 - 0.12 12.6 0.4 0.25 11.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) NPCBM_assoc PF10633.9 AJW70740.1 - 0.0061 16.8 2.8 1.1 9.5 0.1 4.2 4 0 0 4 4 4 1 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF11 PF01345.18 AJW70740.1 - 0.17 12.2 4.8 5.2 7.4 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF11 CBM_15 PF03426.14 AJW70741.1 - 0.028 14.0 1.1 0.057 13.0 0.3 1.9 1 1 1 2 2 2 0 Carbohydrate binding domain (family 15) Pilin_N PF07790.11 AJW70742.1 - 0.00015 22.6 3.4 0.00017 22.5 1.6 1.9 2 0 0 2 2 2 1 Archaeal Type IV pilin, N-terminal Invasin_D3 PF09134.10 AJW70743.1 - 0.0094 16.2 13.2 1 9.7 0.1 5.3 5 0 0 5 5 5 2 Invasin, domain 3 Big_1 PF02369.16 AJW70743.1 - 0.015 15.2 0.3 0.015 15.2 0.3 4.3 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 1) Spore_YhaL PF14147.6 AJW70743.1 - 0.075 12.7 0.7 0.16 11.7 0.7 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL DUF997 PF06196.12 AJW70743.1 - 0.17 11.9 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) MG4 PF17789.1 AJW70743.1 - 0.32 11.1 2.0 3 8.1 0.1 3.4 3 1 1 4 4 4 0 Macroglobulin domain MG4 RecR PF02132.15 AJW70744.1 - 0.011 15.3 0.9 1 9.0 0.1 2.3 2 0 0 2 2 2 0 RecR protein zinc_ribbon_11 PF11682.8 AJW70744.1 - 0.041 13.9 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Probable zinc-ribbon UbiA PF01040.18 AJW70745.1 - 3.2e-29 102.0 12.0 3.9e-29 101.7 12.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family SpecificRecomb PF10136.9 AJW70745.1 - 0.18 10.1 0.3 0.27 9.5 0.3 1.2 1 0 0 1 1 1 0 Site-specific recombinase Aldo_ket_red PF00248.21 AJW70746.1 - 2e-22 79.7 0.2 9.9e-21 74.2 0.2 2.4 1 1 0 1 1 1 1 Aldo/keto reductase family DUF321 PF03778.13 AJW70746.1 - 0.2 11.4 1.1 0.45 10.2 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF321) YHS PF04945.13 AJW70749.1 - 4.3e-14 52.3 0.1 5.1e-14 52.1 0.1 1.0 1 0 0 1 1 1 1 YHS domain Arc_trans_TRASH PF08394.10 AJW70749.1 - 0.00012 22.4 1.7 0.00016 21.9 1.7 1.2 1 0 0 1 1 1 1 Archaeal TRASH domain ATPase-cat_bd PF12156.8 AJW70749.1 - 0.00016 22.3 0.2 0.0002 22.1 0.2 1.1 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Asn_synthase PF00733.21 AJW70750.1 - 7.7e-39 134.3 0.0 4.7e-22 79.1 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase QueC PF06508.13 AJW70750.1 - 2.2e-05 24.1 0.1 8.3e-05 22.2 0.1 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 AJW70750.1 - 3.9e-05 22.9 0.1 6.3e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 AJW70750.1 - 0.0024 17.6 0.0 0.0057 16.4 0.0 1.6 1 1 0 1 1 1 1 PP-loop family ThiI PF02568.14 AJW70750.1 - 0.0027 17.3 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) DZR PF12773.7 AJW70750.1 - 0.003 17.5 1.4 0.031 14.3 0.4 2.3 2 0 0 2 2 2 1 Double zinc ribbon DUF815 PF05673.13 AJW70750.1 - 0.0031 16.7 0.0 0.0046 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) tRNA_Me_trans PF03054.16 AJW70750.1 - 0.004 16.0 0.0 0.0078 15.0 0.0 1.6 1 1 0 1 1 1 1 tRNA methyl transferase MIIP PF15734.5 AJW70750.1 - 0.026 14.0 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Migration and invasion-inhibitory zf-ribbon_3 PF13248.6 AJW70750.1 - 0.3 10.5 8.0 1.7 8.1 3.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AJW70750.1 - 0.52 10.1 5.7 4.7 7.1 5.7 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Cript PF10235.9 AJW70750.1 - 0.6 10.7 4.7 1.5 9.5 0.7 2.7 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT UPF0547 PF10571.9 AJW70750.1 - 0.63 10.2 4.4 0.59 10.3 2.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HTH_3 PF01381.22 AJW70751.1 - 3.4e-05 23.8 0.0 8.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 AJW70751.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_19 PF12844.7 AJW70751.1 - 0.021 14.8 0.1 0.088 12.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 AJW70751.1 - 0.06 13.3 1.1 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 HTH domain Cro PF09048.10 AJW70751.1 - 0.073 13.1 0.0 0.28 11.3 0.0 1.9 2 1 0 2 2 2 0 Cro Alba PF01918.21 AJW70752.1 - 2.3e-11 43.3 0.5 3.1e-11 42.9 0.5 1.2 1 0 0 1 1 1 1 Alba RNA_pol_Rpb6 PF01192.22 AJW70753.1 - 2.3e-11 43.4 0.4 4.7e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb6 YqzH PF14164.6 AJW70753.1 - 0.11 12.6 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 YqzH-like protein Cyclophil_like PF04126.13 AJW70754.1 - 1.7e-09 37.5 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 AJW70754.1 - 4.7e-06 26.5 0.0 6.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like family Ribosomal_S25 PF03297.15 AJW70755.1 - 2.3e-08 34.1 4.8 2.9e-08 33.8 4.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.19 AJW70755.1 - 0.0052 16.6 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AJW70755.1 - 0.089 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Flavi_NS2B PF01002.19 AJW70755.1 - 0.1 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B DS PF01916.17 AJW70757.1 - 2.7e-76 256.6 0.0 3.1e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Ada_Zn_binding PF02805.16 AJW70760.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Metal binding domain of Ada Siah-Interact_N PF09032.11 AJW70761.1 - 0.052 13.9 2.5 0.064 13.6 2.4 1.3 1 1 0 1 1 1 0 Siah interacting protein, N terminal DUF4873 PF16170.5 AJW70763.1 - 0.0078 16.4 0.0 0.008 16.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4873) C1_2 PF03107.16 AJW70763.1 - 0.11 12.8 4.1 0.54 10.6 0.3 2.1 2 0 0 2 2 2 0 C1 domain tRNA-Thr_ED PF08915.11 AJW70765.1 - 9.3e-43 145.6 0.1 1.8e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.20 AJW70765.1 - 9.7e-25 86.6 0.4 1.9e-24 85.6 0.4 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AJW70765.1 - 9.4e-16 58.3 0.2 3.6e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 AJW70765.1 - 0.0049 16.4 0.2 0.0086 15.6 0.2 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Arginase PF00491.21 AJW70766.1 - 4.8e-68 229.7 0.1 5.9e-68 229.4 0.1 1.0 1 0 0 1 1 1 1 Arginase family HypA PF01155.19 AJW70767.1 - 0.0022 18.0 1.3 0.0024 17.9 1.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ephrin_rec_like PF07699.13 AJW70767.1 - 0.01 15.6 1.4 0.013 15.3 1.4 1.2 1 0 0 1 1 1 0 Putative ephrin-receptor like DZR PF12773.7 AJW70767.1 - 0.011 15.8 1.2 0.014 15.4 1.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 AJW70767.1 - 0.014 15.3 1.9 0.017 15.0 1.9 1.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Rep_fac-A_C PF08646.10 AJW70767.1 - 0.026 14.3 1.8 0.028 14.1 1.8 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain OrfB_Zn_ribbon PF07282.11 AJW70767.1 - 0.036 14.0 1.5 0.044 13.7 1.5 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2797 PF10977.8 AJW70767.1 - 0.081 12.8 0.9 0.09 12.7 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Zn-ribbon_8 PF09723.10 AJW70767.1 - 0.49 10.5 5.6 1.3 9.2 5.7 1.6 1 1 1 2 2 2 0 Zinc ribbon domain CDP-OH_P_transf PF01066.21 AJW70768.1 - 1.3e-11 45.1 0.4 1.3e-11 45.1 0.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Phage_holin_2_4 PF16082.5 AJW70768.1 - 2.7 7.8 5.9 3 7.6 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Ribosomal_S26e PF01283.19 AJW70769.1 - 2.7e-24 85.7 0.6 3.3e-24 85.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e CxC5 PF18718.1 AJW70769.1 - 0.013 15.6 0.3 0.016 15.3 0.3 1.1 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases zf-dskA_traR PF01258.17 AJW70769.1 - 0.024 14.6 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger ADD_ATRX PF17981.1 AJW70769.1 - 0.03 14.2 0.3 0.03 14.2 0.3 1.6 2 0 0 2 2 2 0 Cysteine Rich ADD domain zinc_ribbon_4 PF13717.6 AJW70769.1 - 0.13 12.2 1.8 0.56 10.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 AJW70769.1 - 0.53 9.9 2.0 0.55 9.9 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TrmB PF01978.19 AJW70770.1 - 2.5e-09 36.9 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 AJW70770.1 - 0.0057 16.5 0.3 0.02 14.8 0.3 2.0 1 1 0 1 1 1 1 TFIIE alpha subunit MarR_2 PF12802.7 AJW70770.1 - 0.0059 16.5 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AJW70770.1 - 0.0074 16.2 0.0 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 MarR family DUF1854 PF08909.11 AJW70770.1 - 0.012 15.4 1.3 0.76 9.6 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1854) HTH_36 PF13730.6 AJW70770.1 - 0.026 14.5 0.3 0.076 13.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 AJW70770.1 - 0.055 13.6 0.7 0.32 11.2 0.1 2.4 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC DUF3446 PF11928.8 AJW70771.1 - 0.32 11.3 4.5 0.087 13.1 1.2 1.7 2 0 0 2 2 2 0 Early growth response N-terminal domain PfkB PF00294.24 AJW70772.1 - 5e-10 39.2 0.0 3.2e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NOB1_Zn_bind PF08772.11 AJW70772.1 - 0.072 13.3 3.0 0.19 11.9 2.0 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Phos_pyr_kin PF08543.12 AJW70772.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase SHR3_chaperone PF08229.11 AJW70773.1 - 0.023 13.7 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 TAP42 PF04177.12 AJW70773.1 - 0.17 11.0 0.1 0.23 10.5 0.1 1.3 1 1 0 1 1 1 0 TAP42-like family TerY_C PF15616.6 AJW70774.1 - 0.03 14.4 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain CDC24_OB3 PF17244.2 AJW70774.1 - 0.17 11.6 1.7 2.9 7.6 0.0 2.0 1 1 1 2 2 2 0 Cell division control protein 24, OB domain 3 DUF3139 PF11337.8 AJW70775.1 - 0.0098 16.5 0.3 0.0098 16.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) NAD_kinase PF01513.21 AJW70776.1 - 1.1e-28 100.3 0.1 2.2e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 ATP-NAD kinase TrmB PF01978.19 AJW70776.1 - 3.5e-05 23.6 0.7 0.0064 16.3 0.2 2.9 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AJW70776.1 - 4.5e-05 22.9 0.1 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJW70776.1 - 0.00016 21.6 0.6 0.00035 20.4 0.1 1.8 2 0 0 2 2 2 1 MarR family RNA_pol_Rpc34 PF05158.12 AJW70776.1 - 0.00092 18.7 0.3 0.0013 18.2 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 AJW70776.1 - 0.0026 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 MarR family TPALS PF18178.1 AJW70776.1 - 0.0089 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 TIR- and PNP-associating SLOG family HTH_27 PF13463.6 AJW70776.1 - 0.015 15.8 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain CTP_synth_N PF06418.14 AJW70777.1 - 1.8e-116 388.1 0.3 3e-116 387.4 0.3 1.4 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AJW70777.1 - 3.5e-54 183.5 0.0 6.1e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJW70777.1 - 9.3e-12 45.2 0.0 1e-10 41.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 AJW70777.1 - 0.0069 16.5 0.0 0.037 14.1 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 AJW70777.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Copper-bind PF00127.20 AJW70778.1 - 0.00015 22.1 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Trp_syntA PF00290.20 AJW70779.1 - 6.2e-82 274.3 0.4 7.4e-82 274.1 0.4 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain DHO_dh PF01180.21 AJW70779.1 - 7.1e-09 35.3 0.5 9.8e-09 34.8 0.5 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AJW70779.1 - 1e-07 31.6 0.2 4e-07 29.7 0.1 1.9 3 0 0 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.18 AJW70779.1 - 1e-05 24.8 0.0 0.00015 20.9 0.0 2.3 1 1 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AJW70779.1 - 0.002 17.2 0.6 0.005 15.9 0.3 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 AJW70779.1 - 0.0032 16.8 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IGPS PF00218.21 AJW70779.1 - 0.0079 15.4 0.0 0.37 9.9 0.0 2.2 1 1 1 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 AJW70779.1 - 0.01 15.0 0.3 0.028 13.6 0.1 1.9 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PcrB PF01884.17 AJW70779.1 - 0.013 15.0 1.2 0.022 14.2 0.4 1.8 2 1 0 2 2 2 0 PcrB family TMP-TENI PF02581.17 AJW70779.1 - 0.048 13.0 0.4 0.13 11.6 0.4 1.8 1 1 0 1 1 1 0 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 AJW70779.1 - 0.13 11.6 0.2 0.19 11.1 0.2 1.4 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PALP PF00291.25 AJW70780.1 - 2e-45 155.4 1.4 2.6e-45 155.1 1.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IGPS PF00218.21 AJW70781.1 - 7.1e-72 241.6 2.7 8.5e-72 241.4 2.7 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 AJW70781.1 - 2e-07 30.9 0.1 4.2e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 AJW70781.1 - 2.7e-05 23.5 0.9 6.1e-05 22.3 0.2 2.0 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 AJW70781.1 - 6.4e-05 22.1 0.0 0.0036 16.4 0.0 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.21 AJW70781.1 - 0.0075 15.8 0.0 0.041 13.3 0.0 1.9 2 1 0 2 2 2 1 Histidine biosynthesis protein Cellulase PF00150.18 AJW70781.1 - 0.094 12.1 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 AJW70781.1 - 0.098 12.1 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Glycos_transf_3 PF00591.21 AJW70782.1 - 5.9e-78 262.0 0.5 9.4e-78 261.3 0.5 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AJW70782.1 - 2e-13 50.0 0.1 5e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DnaB_2 PF07261.11 AJW70783.1 - 0.032 14.0 0.7 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Replication initiation and membrane attachment GATase PF00117.28 AJW70784.1 - 2.2e-54 184.1 0.3 2.5e-54 184.0 0.3 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJW70784.1 - 9.9e-10 38.5 0.6 3.6e-09 36.7 0.6 1.8 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJW70784.1 - 0.00013 21.9 0.2 0.0003 20.7 0.2 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Chorismate_bind PF00425.18 AJW70785.1 - 8.3e-93 310.7 0.0 2.6e-92 309.0 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AJW70785.1 - 6.6e-22 78.3 1.8 2.5e-18 66.6 0.2 3.1 2 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region zf-HC5HC2H PF13771.6 AJW70786.1 - 0.026 14.7 1.7 0.028 14.7 1.2 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain Rad50_zn_hook PF04423.14 AJW70786.1 - 0.066 13.1 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif HATPase_c PF02518.26 AJW70788.1 - 9.3e-18 64.8 0.1 2.6e-17 63.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AJW70788.1 - 4.3e-12 46.3 8.2 5.3e-12 46.0 4.8 2.3 2 0 0 2 2 2 1 Cache domain HisKA PF00512.25 AJW70788.1 - 2e-10 40.5 0.0 5.9e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW70788.1 - 2.3e-10 40.3 0.1 1.1e-09 38.1 0.1 2.2 1 0 0 1 1 1 1 GHKL domain HAMP PF00672.25 AJW70788.1 - 9.9e-09 35.5 0.0 7e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 HAMP domain DUF948 PF06103.11 AJW70788.1 - 0.00082 19.6 5.3 0.92 9.8 0.2 3.6 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 AJW70788.1 - 1.4 8.6 10.2 0.049 13.3 2.3 2.1 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Response_reg PF00072.24 AJW70789.1 - 2.4e-22 79.2 0.6 2.7e-22 79.0 0.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AJW70789.1 - 0.009 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ DNA_gyraseA_C PF03989.13 AJW70790.1 - 0.063 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller Gly_acyl_tr_C PF08444.10 AJW70790.1 - 0.15 12.3 0.1 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF5130 PF17174.4 AJW70793.1 - 0.16 12.2 0.1 6.2 7.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5130) HTH_24 PF13412.6 AJW70794.1 - 0.0034 16.9 0.3 0.0073 15.9 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 AJW70794.1 - 0.01 15.5 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AJW70794.1 - 0.013 15.5 0.2 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AJW70794.1 - 0.017 15.0 0.1 0.059 13.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family PCI PF01399.27 AJW70794.1 - 0.083 13.4 0.7 0.29 11.7 0.7 2.0 1 0 0 1 1 1 0 PCI domain DUF5601 PF18151.1 AJW70794.1 - 0.38 11.1 2.3 28 5.1 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) Cnn_1N PF07989.11 AJW70795.1 - 0.00033 20.8 9.5 0.0005 20.2 1.7 2.9 2 1 1 3 3 3 1 Centrosomin N-terminal motif 1 CorA PF01544.18 AJW70795.1 - 0.00053 19.4 0.8 0.055 12.8 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Apolipoprotein PF01442.18 AJW70795.1 - 0.00069 19.5 4.1 0.32 10.8 0.5 2.3 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain Shugoshin_N PF07558.11 AJW70795.1 - 0.0052 16.6 6.2 0.27 11.1 0.4 3.0 3 0 0 3 3 2 2 Shugoshin N-terminal coiled-coil region FlxA PF14282.6 AJW70795.1 - 0.0069 16.3 12.8 0.031 14.3 2.4 2.7 2 1 0 2 2 2 1 FlxA-like protein IL3 PF02059.15 AJW70795.1 - 0.012 15.6 0.1 0.032 14.3 0.1 1.7 1 0 0 1 1 1 0 Interleukin-3 Lzipper-MIP1 PF14389.6 AJW70795.1 - 0.018 15.3 5.1 4.8 7.5 0.0 3.9 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Csm1_N PF18504.1 AJW70795.1 - 0.02 15.2 5.4 1.4 9.3 0.1 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain LPP PF04728.13 AJW70795.1 - 0.023 15.1 5.6 0.99 9.8 0.0 3.2 3 1 0 3 3 2 0 Lipoprotein leucine-zipper bZIP_1 PF00170.21 AJW70795.1 - 0.026 14.6 2.0 1.7 8.8 0.3 2.9 2 0 0 2 2 2 0 bZIP transcription factor DUF4349 PF14257.6 AJW70795.1 - 0.036 13.5 0.8 0.074 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF2019 PF09450.10 AJW70795.1 - 0.047 13.6 0.6 2.7 8.0 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF2019) MtrB PF05440.12 AJW70795.1 - 0.066 13.6 0.3 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B AKNA PF12443.8 AJW70795.1 - 0.084 13.5 3.9 2 9.1 0.4 2.9 2 1 1 3 3 2 0 AT-hook-containing transcription factor NPV_P10 PF05531.12 AJW70795.1 - 0.16 12.4 7.3 2 9.0 2.6 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 AJW70795.1 - 0.18 11.0 1.2 1.3 8.2 0.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein Ax_dynein_light PF10211.9 AJW70795.1 - 0.2 11.6 4.8 0.19 11.7 0.3 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Baculo_PEP_C PF04513.12 AJW70795.1 - 0.23 11.5 7.4 1.6 8.8 1.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 AJW70795.1 - 0.27 10.8 3.5 1.9 8.0 0.3 2.2 2 0 0 2 2 2 0 Intermediate filament protein UPF0242 PF06785.11 AJW70795.1 - 0.45 10.6 0.0 0.45 10.6 0.0 2.5 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 AJW70795.1 - 0.46 11.1 6.8 1.4 9.6 0.2 2.8 3 0 0 3 3 2 0 Initiation control protein YabA Spc24 PF08286.11 AJW70795.1 - 0.48 10.7 10.4 1 9.7 1.2 3.2 3 1 0 3 3 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 AJW70795.1 - 0.51 10.8 9.1 1.6 9.2 0.7 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 AJW70795.1 - 0.66 10.2 12.1 7.2 6.9 2.9 3.8 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Swi5 PF07061.11 AJW70795.1 - 0.72 10.0 9.2 1.2 9.3 2.5 2.9 2 1 1 3 3 3 0 Swi5 DUF4094 PF13334.6 AJW70795.1 - 0.78 10.2 6.8 4.7 7.7 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) SlyX PF04102.12 AJW70795.1 - 1.1 10.0 5.1 3.4 8.4 0.4 3.1 2 2 0 2 2 2 0 SlyX DUF1319 PF07028.11 AJW70795.1 - 1.1 9.5 4.9 2.9 8.1 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1319) Vps51 PF08700.11 AJW70795.1 - 1.5 8.9 4.8 1.4 9.0 0.3 2.9 3 0 0 3 3 2 0 Vps51/Vps67 Med9 PF07544.13 AJW70795.1 - 2 8.5 7.3 4.2 7.5 0.8 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 AJW70795.1 - 2.4 8.7 5.9 1.6 9.2 0.2 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region CCDC-167 PF15188.6 AJW70795.1 - 2.6 8.5 4.7 5.1 7.5 0.6 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF5082 PF16888.5 AJW70795.1 - 4.4 7.6 7.8 5.9 7.2 0.1 3.1 3 1 1 4 4 3 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 AJW70795.1 - 4.7 7.6 12.7 1.1 9.6 0.4 2.6 3 0 0 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF16 PF01519.16 AJW70795.1 - 4.8 7.7 7.2 1.5 9.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 AJW70795.1 - 8.9 6.4 8.6 1.8e+02 2.2 0.6 3.4 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein YlqD PF11068.8 AJW70795.1 - 9 6.7 9.5 12 6.3 0.2 3.1 3 0 0 3 3 3 0 YlqD protein CorA PF01544.18 AJW70796.1 - 6.2e-67 226.0 6.9 6.2e-67 226.0 6.9 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4003 PF13170.6 AJW70796.1 - 0.0025 17.3 0.6 0.0025 17.3 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4003) Herpes_UL92 PF03048.14 AJW70796.1 - 0.35 10.6 4.0 0.25 11.1 0.8 2.1 1 1 0 2 2 2 0 UL92 family Ion_trans PF00520.31 AJW70797.1 - 1.7e-30 106.1 11.0 2e-30 105.8 11.0 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AJW70797.1 - 4.2e-13 49.1 5.8 4.2e-13 49.1 5.8 2.2 2 1 1 3 3 3 1 Ion channel YhfH PF14149.6 AJW70797.1 - 0.11 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 YhfH-like protein zf-ribbon_3 PF13248.6 AJW70797.1 - 0.12 11.9 0.6 0.19 11.2 0.6 1.2 1 0 0 1 1 1 0 zinc-ribbon domain DUF5367 PF17329.2 AJW70797.1 - 0.39 10.9 7.4 0.27 11.4 0.3 3.0 4 0 0 4 4 4 0 Family of unknown function (DUF5367) DUF2678 PF10856.8 AJW70798.1 - 0.076 12.9 7.6 0.34 10.9 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) BshC PF10079.9 AJW70798.1 - 0.63 8.7 9.1 0.78 8.4 9.1 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF3810 PF12725.7 AJW70798.1 - 3.9 6.7 15.7 2.4e+03 -2.4 15.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Endostatin PF06482.11 AJW70799.1 - 0.13 11.7 0.8 0.19 11.2 0.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RNA_pol_Rpc4 PF05132.14 AJW70799.1 - 1.9 8.9 7.0 3.4 8.1 7.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PD40 PF07676.12 AJW70800.1 - 0.019 14.9 0.4 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ATP-synt_E PF05680.12 AJW70800.1 - 0.1 12.9 4.1 0.19 12.1 4.1 1.3 1 0 0 1 1 1 0 ATP synthase E chain DUF4337 PF14235.6 AJW70800.1 - 1.2 9.2 4.9 2.6 8.1 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2116 PF09889.9 AJW70802.1 - 0.0017 18.3 1.3 0.002 18.1 1.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) PLATZ PF04640.14 AJW70802.1 - 0.011 16.3 0.6 0.012 16.2 0.6 1.1 1 0 0 1 1 1 0 PLATZ transcription factor Acetyltransf_1 PF00583.25 AJW70804.1 - 1.1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AJW70804.1 - 2.3e-06 27.7 0.0 0.033 14.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJW70804.1 - 0.0046 17.4 0.0 0.018 15.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Amidohydro_2 PF04909.14 AJW70805.1 - 4e-29 102.3 0.0 1.1e-28 100.8 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 AJW70805.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase FGase PF05013.12 AJW70807.1 - 5.2e-39 134.7 0.0 6.3e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase SGTA_dimer PF16546.5 AJW70807.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Homodimerisation domain of SGTA Na_H_Exchanger PF00999.21 AJW70808.1 - 1.1e-59 202.1 49.2 1.1e-59 202.1 49.2 2.2 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family SHOCT PF09851.9 AJW70809.1 - 1.9e-05 24.3 3.7 7e-05 22.4 3.7 2.0 1 1 0 1 1 1 1 Short C-terminal domain SH3BP5 PF05276.14 AJW70809.1 - 0.00043 20.2 1.0 0.00064 19.6 1.0 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) RNA_pol_A_CTD PF03118.15 AJW70809.1 - 0.021 14.6 0.8 0.061 13.1 0.8 1.8 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain GvpG PF05120.12 AJW70809.1 - 0.069 13.2 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 Gas vesicle protein G TCTP PF00838.17 AJW70809.1 - 1.6 9.1 8.3 4 7.7 8.3 1.6 1 1 0 1 1 1 0 Translationally controlled tumour protein YtxH PF12732.7 AJW70809.1 - 2.7 8.6 7.8 83 3.8 7.8 2.5 1 1 0 1 1 1 0 YtxH-like protein SHR3_chaperone PF08229.11 AJW70810.1 - 0.099 11.6 0.9 0.13 11.2 0.9 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 ETRAMP PF09716.10 AJW70810.1 - 0.83 9.8 6.7 0.19 11.8 2.5 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PRC PF05239.16 AJW70811.1 - 1.1e-15 57.5 2.3 1.1e-06 28.6 1.2 2.1 2 0 0 2 2 2 2 PRC-barrel domain GTP_EFTU_D4 PF14578.6 AJW70811.1 - 0.00018 21.4 1.2 0.0054 16.6 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 DUF2171 PF09939.9 AJW70811.1 - 0.0022 18.2 0.3 0.03 14.6 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2171) MlaD PF02470.20 AJW70811.1 - 0.0025 18.1 0.3 0.032 14.5 0.2 2.2 1 1 1 2 2 2 1 MlaD protein Tricorn_PDZ PF14685.6 AJW70811.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain RNA_pol_Rpb2_6 PF00562.28 AJW70811.1 - 0.088 11.9 0.2 0.13 11.3 0.2 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 6 AsnC_trans_reg PF01037.21 AJW70812.1 - 4.7e-10 39.3 0.0 5.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain ACT_4 PF13291.6 AJW70812.1 - 0.048 14.2 0.0 0.067 13.8 0.0 1.2 1 0 0 1 1 1 0 ACT domain Na_H_Exchanger PF00999.21 AJW70814.1 - 3.1e-53 180.9 51.3 4.1e-53 180.5 51.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CBS PF00571.28 AJW70814.1 - 5.8e-12 45.9 2.3 3.5e-08 33.8 0.3 2.7 2 0 0 2 2 2 2 CBS domain Acetyltransf_4 PF13420.7 AJW70814.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SDF PF00375.18 AJW70815.1 - 5.3e-112 374.7 46.4 6e-112 374.5 46.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family EF1_GNE PF00736.19 AJW70815.1 - 0.037 14.2 0.6 0.94 9.7 0.0 2.4 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain CDC24 PF06395.11 AJW70815.1 - 0.058 13.6 0.1 0.25 11.6 0.1 2.1 1 0 0 1 1 1 0 CDC24 Calponin Ion_trans_2 PF07885.16 AJW70816.1 - 2.2e-16 59.6 9.3 4.9e-16 58.5 9.3 1.5 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 AJW70816.1 - 4.5e-08 32.6 1.6 5.7e-08 32.3 1.6 1.1 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 AJW70816.1 - 3.3e-06 27.0 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel IRK PF01007.20 AJW70816.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Pilin_N PF07790.11 AJW70816.1 - 0.076 14.0 2.4 7.3 7.6 0.2 2.3 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Usp PF00582.26 AJW70817.1 - 9.7e-31 107.2 0.0 1.1e-30 107.0 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family NAD_binding_1 PF00175.21 AJW70817.1 - 0.0053 17.4 0.1 0.021 15.5 0.1 1.7 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Bul1_C PF04426.12 AJW70817.1 - 0.025 14.0 1.6 0.033 13.6 1.6 1.2 1 0 0 1 1 1 0 Bul1 C terminus Phage_Treg PF04761.12 AJW70817.1 - 0.064 13.4 0.7 0.5 10.5 0.7 2.2 1 1 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator DUF21 PF01595.20 AJW70818.1 - 4.9e-43 146.9 0.2 7.2e-43 146.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 AJW70818.1 - 1e-15 57.9 0.3 3.1e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain PI_PP_I PF18363.1 AJW70819.1 - 0.011 15.9 1.0 0.016 15.4 0.4 1.6 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain Gemini_AL1_M PF08283.11 AJW70819.1 - 0.057 13.5 0.4 0.83 9.8 0.2 2.1 2 0 0 2 2 2 0 Geminivirus rep protein central domain Spore_GerAC PF05504.11 AJW70821.1 - 0.041 14.1 5.5 0.063 13.5 5.5 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal PP2C_C PF07830.13 AJW70821.1 - 0.068 13.6 2.0 0.12 12.9 2.0 1.3 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Colicin-DNase PF12639.7 AJW70821.1 - 0.22 12.4 2.7 0.36 11.7 1.7 1.8 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF4634 PF15465.6 AJW70822.1 - 0.26 11.6 2.1 0.39 11.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) PDDEXK_1 PF12705.7 AJW70823.1 - 2.3e-09 37.6 1.4 2.6e-08 34.1 1.4 1.9 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 AJW70823.1 - 0.0024 17.7 3.5 0.0026 17.6 2.2 1.7 2 0 0 2 2 2 1 PDDEXK-like domain of unknown function (DUF3799) DUF2800 PF10926.8 AJW70823.1 - 0.0074 15.6 2.5 0.049 12.9 0.1 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF2800) Dala_Dala_lig_C PF07478.13 AJW70824.1 - 4.5e-33 114.5 0.0 7.4e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AJW70824.1 - 3e-12 46.9 0.1 5.8e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AJW70824.1 - 3.5e-12 46.2 0.5 7.6e-11 41.9 0.1 3.1 2 1 0 2 2 2 1 ATP-grasp domain Peptidase_M20 PF01546.28 AJW70824.1 - 9.4e-10 38.5 0.0 2.5e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 CPSase_L_D2 PF02786.17 AJW70824.1 - 2e-09 37.3 0.0 3.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 AJW70824.1 - 9.3e-06 25.4 0.1 0.00017 21.2 0.1 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 AJW70824.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 AJW70824.1 - 0.00061 19.4 0.0 0.0071 15.9 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 AJW70824.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TIR_2 PF13676.6 AJW70824.1 - 0.11 13.1 0.0 6.6 7.4 0.0 2.6 2 0 0 2 2 2 0 TIR domain Pyr_redox_2 PF07992.14 AJW70825.1 - 2.2e-39 135.5 0.1 2.8e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJW70825.1 - 7.5e-07 29.6 1.2 0.00012 22.6 1.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase E1_UFD PF09358.10 AJW70825.1 - 0.059 14.1 0.1 0.21 12.3 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin fold domain Hexapep PF00132.24 AJW70826.1 - 9.1e-14 50.6 16.6 9.2e-05 22.0 0.5 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJW70826.1 - 8.4e-05 22.2 15.3 0.0087 15.8 2.8 5.0 5 1 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AJW70826.1 - 0.14 11.1 0.3 0.45 9.4 0.3 1.7 1 1 0 1 1 1 0 L-fucokinase Hexapep PF00132.24 AJW70827.1 - 4.8e-23 80.0 43.2 1.7e-07 30.7 5.1 4.3 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJW70827.1 - 3.4e-09 36.3 16.9 0.00027 20.6 4.2 4.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AJW70828.1 - 2.5e-19 68.2 33.2 1.9e-07 30.5 2.7 3.8 1 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJW70828.1 - 4e-10 39.3 22.5 0.00015 21.4 10.1 4.6 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AJW70828.1 - 0.034 13.1 0.3 0.047 12.6 0.3 1.3 1 0 0 1 1 1 0 L-fucokinase DUF3686 PF12458.8 AJW70828.1 - 0.037 12.5 2.6 0.2 10.1 0.4 2.0 1 1 1 2 2 2 0 ATPase involved in DNA repair DUF1416 PF07210.12 AJW70828.1 - 0.67 9.9 4.8 4.2 7.3 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1416) G_glu_transpept PF01019.21 AJW70829.1 - 1.1e-104 351.1 0.0 1.2e-104 350.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.18 AJW70829.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Asparaginase UPF0180 PF03698.13 AJW70829.1 - 0.18 12.0 0.0 12 6.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) zf-MYST PF17772.1 AJW70830.1 - 0.0062 16.1 0.0 0.0066 16.0 0.0 1.1 1 0 0 1 1 1 1 MYST family zinc finger domain GDC-P PF02347.16 AJW70831.1 - 0.0063 15.4 0.2 0.0071 15.2 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein DUF4956 PF16316.5 AJW70831.1 - 0.014 15.1 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) sCache_3_2 PF17203.4 AJW70833.1 - 0.031 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Single cache domain 3 DUF4294 PF14127.6 AJW70837.1 - 0.094 12.6 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) zf-C2H2_4 PF13894.6 AJW70838.1 - 0.01 16.6 2.9 0.03 15.2 2.9 1.8 1 1 0 1 1 1 0 C2H2-type zinc finger PSII PF00421.19 AJW70840.1 - 0.24 10.0 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein TackOD1 PF18551.1 AJW70841.1 - 0.05 13.3 9.2 0.058 13.1 9.2 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 YacG PF03884.14 AJW70841.1 - 0.059 13.1 3.9 2.5 7.9 0.6 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_4 PF14570.6 AJW70841.1 - 0.16 11.8 8.0 0.43 10.4 2.9 2.8 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Spt4 PF06093.13 AJW70841.1 - 0.26 11.4 9.5 3.8 7.7 4.7 2.1 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger Rubredoxin_2 PF18073.1 AJW70841.1 - 0.33 10.7 0.2 0.33 10.7 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Sgf11 PF08209.11 AJW70841.1 - 0.47 10.1 5.1 1.1 8.8 0.1 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.6 AJW70841.1 - 0.54 9.7 9.3 0.68 9.4 0.5 2.5 2 1 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 AJW70841.1 - 1.3 9.0 9.9 2.5 8.2 9.9 1.5 1 1 0 1 1 1 0 zinc-ribbons zf-TFIIB PF13453.6 AJW70841.1 - 1.8 7.9 8.5 0.97 8.8 0.5 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger Rad50_zn_hook PF04423.14 AJW70841.1 - 2.7 7.9 10.1 0.55 10.1 1.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif OrfB_Zn_ribbon PF07282.11 AJW70841.1 - 5.1 7.1 8.1 1.6 8.7 0.8 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain C1_4 PF07975.12 AJW70842.1 - 0.072 13.3 5.4 0.12 12.6 5.4 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain Peptidase_M10 PF00413.24 AJW70843.1 - 3.8e-08 33.3 0.5 1.5e-07 31.4 0.5 1.9 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 AJW70843.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.6 AJW70843.1 - 0.014 15.5 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 AJW70843.1 - 0.016 15.7 0.5 0.035 14.6 0.5 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 AJW70843.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 AJW70843.1 - 0.038 12.6 0.4 0.06 11.9 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.5 AJW70843.1 - 2 7.5 6.0 8.3 5.5 0.1 2.7 3 0 0 3 3 3 0 Met-zincin Syntaxin_2 PF14523.6 AJW70843.1 - 5.8 7.4 9.3 3.5 8.0 5.0 2.6 2 1 0 2 2 2 0 Syntaxin-like protein ATP1G1_PLM_MAT8 PF02038.16 AJW70844.1 - 1.2 8.7 3.7 1.8 8.1 3.4 1.5 1 1 0 1 1 1 0 ATP1G1/PLM/MAT8 family Rubredoxin PF00301.20 AJW70845.1 - 0.0042 17.1 0.8 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Rubredoxin Elf1 PF05129.13 AJW70845.1 - 0.038 14.1 2.5 0.054 13.5 0.2 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.12 AJW70845.1 - 0.083 12.9 3.1 0.11 12.5 3.1 1.3 1 1 0 1 1 1 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 AJW70845.1 - 0.094 12.7 2.8 0.48 10.4 2.9 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PHD PF00628.29 AJW70845.1 - 0.12 12.3 4.3 0.28 11.1 4.3 1.6 1 1 0 1 1 1 0 PHD-finger zinc_ribbon_10 PF10058.9 AJW70845.1 - 0.21 11.3 5.5 1.1 9.0 5.5 1.9 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PLAC9 PF15205.6 AJW70848.1 - 0.18 12.2 0.2 0.26 11.7 0.2 1.2 1 0 0 1 1 1 0 Placenta-specific protein 9 zf-C2H2_3rep PF18868.1 AJW70849.1 - 0.0011 19.7 0.2 0.0011 19.7 0.2 1.0 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 AJW70849.1 - 0.0013 19.4 1.3 0.0018 18.9 1.3 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 AJW70849.1 - 0.0061 16.9 1.8 0.0067 16.8 1.8 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 AJW70849.1 - 0.035 14.6 0.9 0.049 14.1 0.9 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type GIY-YIG PF01541.24 AJW70850.1 - 5.1e-05 23.5 0.2 6.7e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain RPW8 PF05659.11 AJW70850.1 - 0.067 12.9 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Helicase_C_2 PF13307.6 AJW70851.1 - 9.4e-21 74.7 0.0 2.9e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 AJW70851.1 - 1.2e-09 38.4 5.9 1.4e-09 38.2 1.5 2.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 AJW70851.1 - 1.5e-05 24.7 1.6 1.8e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 AJW70851.1 - 0.00011 22.0 0.5 0.044 13.5 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.6 AJW70851.1 - 0.12 12.7 0.4 2.1 8.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain ILVD_EDD PF00920.21 AJW70853.1 - 3.2e-208 692.5 4.3 3.6e-208 692.4 4.3 1.0 1 0 0 1 1 1 1 Dehydratase family Lar_restr_allev PF14354.6 AJW70854.1 - 0.0033 17.8 0.2 0.0041 17.5 0.2 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar TFIIS_C PF01096.18 AJW70854.1 - 0.018 14.9 1.9 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2225 PF09986.9 AJW70854.1 - 0.023 14.4 2.7 0.059 13.1 2.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_13 PF09855.9 AJW70854.1 - 0.024 14.8 2.6 0.043 14.0 2.6 1.5 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_4 PF13717.6 AJW70854.1 - 0.041 13.8 0.4 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 AJW70854.1 - 0.045 13.8 1.6 0.71 9.9 0.2 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AJW70854.1 - 0.045 13.9 1.3 4.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain CpXC PF14353.6 AJW70854.1 - 0.046 13.8 0.4 0.057 13.5 0.4 1.2 1 0 0 1 1 1 0 CpXC protein DUF35_N PF12172.8 AJW70854.1 - 0.11 12.4 1.3 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TF_Zn_Ribbon PF08271.12 AJW70854.1 - 0.12 11.9 3.5 0.54 9.8 3.5 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 AJW70854.1 - 0.17 12.4 1.6 6.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-trcl PF13451.6 AJW70854.1 - 0.21 11.5 2.5 3 7.8 0.2 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain DUF3797 PF12677.7 AJW70854.1 - 0.34 10.8 2.6 0.72 9.8 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3797) HIT PF01230.23 AJW70856.1 - 1.4e-21 77.0 0.1 1.8e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AJW70856.1 - 9.8e-12 45.4 0.0 1.2e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 AJW70856.1 - 0.017 15.0 0.1 0.026 14.4 0.1 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 eRF1_2 PF03464.15 AJW70857.1 - 1.9e-28 99.4 0.0 1e-27 97.1 0.0 2.0 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 AJW70857.1 - 7.7e-20 71.5 0.4 7.7e-19 68.3 0.1 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 AJW70857.1 - 6.5e-11 42.3 0.0 3.3e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 AJW70857.1 - 2.9e-06 27.6 0.0 5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 AJW70857.1 - 5e-06 26.8 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 HypA PF01155.19 AJW70857.1 - 0.08 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AJW70857.1 - 0.53 10.4 4.8 3.2 8.0 3.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 AJW70857.1 - 1 9.2 2.7 9.7 6.0 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Thioredoxin_4 PF13462.6 AJW70858.1 - 1.2e-33 116.6 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJW70858.1 - 3.3e-13 49.9 0.0 3.6e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJW70858.1 - 7.4e-08 32.8 0.5 2.4e-07 31.2 0.5 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJW70858.1 - 4.2e-06 26.6 0.0 6.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4443 PF14544.6 AJW70859.1 - 3.5e-05 24.0 0.0 4.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) HTH_45 PF14947.6 AJW70859.1 - 0.0035 17.3 0.1 0.0063 16.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 AJW70859.1 - 0.036 13.8 0.4 0.048 13.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Ribosomal_S19e PF01090.19 AJW70859.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e Mrr_N PF14338.6 AJW70859.1 - 0.15 12.3 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain CbtB PF09489.10 AJW70860.1 - 3e-13 49.7 2.3 4e-13 49.2 2.3 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) CbtA PF09490.10 AJW70861.1 - 7.1e-51 173.3 0.3 8e-51 173.1 0.3 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) Romo1 PF10247.9 AJW70861.1 - 0.0098 16.2 0.7 0.14 12.5 0.2 2.8 3 0 0 3 3 3 1 Reactive mitochondrial oxygen species modulator 1 Patatin PF01734.22 AJW70861.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase Acyl_transf_3 PF01757.22 AJW70861.1 - 0.39 9.7 9.5 1 8.3 9.5 1.9 1 1 0 1 1 1 0 Acyltransferase family 5TM-5TMR_LYT PF07694.12 AJW70861.1 - 0.59 9.6 13.7 0.42 10.1 4.4 3.3 3 1 0 3 3 3 0 5TMR of 5TMR-LYT MFS_1 PF07690.16 AJW70861.1 - 2.3 7.0 17.7 0.039 12.9 5.7 2.7 2 1 1 3 3 3 0 Major Facilitator Superfamily CitMHS PF03600.16 AJW70861.1 - 3.4 6.8 8.4 1.7 7.7 2.2 2.1 2 0 0 2 2 2 0 Citrate transporter HTH_20 PF12840.7 AJW70862.1 - 2e-05 24.5 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AJW70862.1 - 0.0001 22.1 0.4 0.00022 21.1 0.4 1.7 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 AJW70862.1 - 0.00051 19.9 0.3 0.00059 19.7 0.3 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit DUF742 PF05331.11 AJW70862.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) SdiA-regulated PF06977.11 AJW70862.1 - 0.077 12.2 0.0 0.081 12.1 0.0 1.0 1 0 0 1 1 1 0 SdiA-regulated HTH_IclR PF09339.10 AJW70862.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.19 AJW70863.1 - 6e-05 22.8 0.1 0.0001 22.1 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AJW70863.1 - 0.00017 21.3 0.1 0.00039 20.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_7 PF02796.15 AJW70863.1 - 0.00032 20.7 0.1 0.00061 19.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DUF4423 PF14394.6 AJW70863.1 - 0.00032 20.5 0.2 0.00035 20.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_20 PF12840.7 AJW70863.1 - 0.00087 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AJW70863.1 - 0.0012 18.7 0.3 0.0023 17.8 0.2 1.6 1 1 0 1 1 1 1 HTH domain DUF1492 PF07374.11 AJW70863.1 - 0.0015 18.6 0.3 0.0022 18.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) FUR PF01475.19 AJW70863.1 - 0.0042 17.2 0.2 0.0058 16.8 0.1 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_23 PF13384.6 AJW70863.1 - 0.0044 16.8 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Fe_dep_repress PF01325.19 AJW70863.1 - 0.016 15.4 0.2 0.026 14.7 0.2 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Mga PF05043.13 AJW70863.1 - 0.022 15.3 0.4 0.038 14.6 0.3 1.6 1 1 0 1 1 1 0 Mga helix-turn-helix domain HTH_IclR PF09339.10 AJW70863.1 - 0.036 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AJW70863.1 - 0.04 13.5 0.4 0.08 12.5 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_22 PF13309.6 AJW70863.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 AJW70863.1 - 0.059 13.3 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 MarR family RepL PF05732.11 AJW70863.1 - 0.062 12.7 0.1 0.098 12.1 0.1 1.4 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) N1221 PF07923.13 AJW70863.1 - 0.085 12.0 0.2 0.094 11.9 0.2 1.1 1 0 0 1 1 1 0 N1221-like protein Sigma70_r4_2 PF08281.12 AJW70863.1 - 0.092 12.4 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_45 PF14947.6 AJW70863.1 - 0.11 12.5 0.7 0.31 11.0 0.2 2.0 1 1 1 2 2 2 0 Winged helix-turn-helix Phosphonate-bd PF12974.7 AJW70864.1 - 1.3e-43 149.4 0.3 1.7e-43 149.0 0.3 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AJW70864.1 - 8e-05 22.2 0.0 0.00024 20.6 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AJW70864.1 - 0.0004 20.4 0.0 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 AJW70864.1 - 0.0015 18.3 0.3 0.0062 16.3 0.1 2.0 2 1 1 3 3 3 1 NMT1-like family Transferrin PF00405.17 AJW70864.1 - 0.0016 17.6 0.0 0.0034 16.6 0.0 1.4 1 1 1 2 2 2 1 Transferrin ABC_tran PF00005.27 AJW70865.1 - 9.1e-34 116.9 0.2 1.3e-33 116.4 0.2 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AJW70865.1 - 1.6e-07 31.0 4.3 1.4e-06 28.0 4.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AJW70865.1 - 3.5e-06 27.1 1.5 0.029 14.2 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AJW70865.1 - 1.1e-05 25.1 0.1 2.3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AJW70865.1 - 0.0018 18.2 0.2 0.0039 17.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 AJW70865.1 - 0.0025 17.1 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.7 AJW70865.1 - 0.004 16.1 2.1 0.0081 15.1 2.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.6 AJW70865.1 - 0.0049 17.1 0.3 0.11 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AJW70865.1 - 0.016 15.7 0.4 0.05 14.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AJW70865.1 - 0.018 14.4 0.5 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 AJW70865.1 - 0.025 13.8 0.5 0.48 9.6 0.5 2.2 1 1 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 AJW70865.1 - 0.045 12.9 0.6 0.11 11.6 0.2 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 AJW70865.1 - 0.062 13.7 0.1 0.084 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 AJW70865.1 - 0.11 12.5 0.9 7.4 6.6 0.3 2.6 2 0 0 2 2 2 0 Dynamin family BPD_transp_1 PF00528.22 AJW70866.1 - 3.2e-16 59.6 13.5 3.2e-16 59.6 13.5 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component MotA_ExbB PF01618.16 AJW70866.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.6 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family PrgI PF12666.7 AJW70866.1 - 0.15 12.8 0.6 0.15 12.8 0.6 3.4 2 1 1 3 3 3 0 PrgI family protein DUF1297 PF06973.12 AJW70867.1 - 1.2e-73 246.6 0.0 1.7e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AJW70867.1 - 2.2e-45 153.5 0.0 3.6e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_3 PF02655.14 AJW70867.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain tRNA-synt_2 PF00152.20 AJW70870.1 - 6e-79 265.4 0.0 7.2e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AJW70870.1 - 2.4e-13 49.9 0.0 4.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AJW70870.1 - 0.022 14.2 0.1 0.16 11.4 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Glu-tRNAGln PF02686.15 AJW70871.1 - 0.029 14.7 1.3 0.05 13.9 0.1 1.8 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Amidase PF01425.21 AJW70872.1 - 1e-136 456.5 0.0 1.1e-136 456.4 0.0 1.0 1 0 0 1 1 1 1 Amidase GatB_N PF02934.15 AJW70873.1 - 1.6e-92 309.8 0.2 9.3e-92 307.3 0.0 1.9 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AJW70873.1 - 1.5e-31 109.3 6.6 2.5e-31 108.6 6.6 1.3 1 0 0 1 1 1 1 GatB domain TMP_2 PF06791.13 AJW70873.1 - 0.04 13.6 0.1 0.09 12.4 0.1 1.6 1 0 0 1 1 1 0 Prophage tail length tape measure protein AMP-binding PF00501.28 AJW70875.1 - 2.5e-76 257.0 0.0 3e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AJW70875.1 - 4.1e-17 62.9 0.1 9.5e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AJW70875.1 - 9e-11 41.5 1.8 1.9e-10 40.5 1.8 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Mycobact_memb PF05423.13 AJW70875.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Mycobacterium membrane protein Mitoc_L55 PF09776.9 AJW70875.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Aminotran_1_2 PF00155.21 AJW70876.1 - 2.3e-39 135.6 0.0 3.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SHOCT PF09851.9 AJW70877.1 - 8.8e-05 22.1 0.6 8.8e-05 22.1 0.6 1.9 2 0 0 2 2 2 1 Short C-terminal domain TrmB PF01978.19 AJW70878.1 - 1.3e-12 47.4 0.0 2.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AJW70878.1 - 4.3e-05 23.2 0.0 8.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 AJW70878.1 - 0.0045 17.3 0.0 0.0077 16.6 0.0 1.5 1 1 0 1 1 1 1 Transcriptional regulator HTH_9 PF08221.11 AJW70878.1 - 0.012 15.7 0.1 0.026 14.6 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Med14 PF08638.11 AJW70878.1 - 0.031 13.7 0.1 0.063 12.7 0.1 1.6 1 1 0 1 1 1 0 Mediator complex subunit MED14 z-alpha PF02295.17 AJW70878.1 - 0.039 14.0 0.0 0.089 12.8 0.0 1.6 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain HTH_24 PF13412.6 AJW70878.1 - 0.041 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AJW70878.1 - 0.047 13.6 0.1 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Arc_PepC_II PF06847.11 AJW70879.1 - 4.4e-09 36.7 0.1 4.4e-09 36.7 0.1 2.6 3 1 0 3 3 3 1 Archaeal Peptidase A24 C-terminus Type II Peptidase_A24 PF01478.18 AJW70879.1 - 2.3e-06 28.0 12.8 4.2e-06 27.1 12.8 1.4 1 0 0 1 1 1 1 Type IV leader peptidase family NMN_transporter PF04973.12 AJW70879.1 - 0.0095 15.9 8.2 0.04 13.9 7.4 1.9 1 1 0 1 1 1 1 Nicotinamide mononucleotide transporter TrmB PF01978.19 AJW70880.1 - 1.6e-11 43.9 0.0 3.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AJW70880.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain PRESAN PF09687.10 AJW70880.1 - 0.015 15.8 1.0 0.015 15.8 1.0 2.4 3 1 0 3 3 3 0 Plasmodium RESA N-terminal HTH_9 PF08221.11 AJW70880.1 - 0.043 13.9 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain PhoQ_Sensor PF08918.10 AJW70880.1 - 0.094 12.6 1.1 0.19 11.5 0.2 2.0 3 0 0 3 3 3 0 PhoQ Sensor HSBP1 PF06825.12 AJW70880.1 - 0.42 10.5 2.6 0.8 9.6 0.6 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ATPase PF06745.13 AJW70881.1 - 2.8e-55 187.2 0.0 3.4e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 KaiC GvpD PF07088.11 AJW70881.1 - 4.8e-08 32.1 0.1 1.1e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 GvpD gas vesicle protein AAA_25 PF13481.6 AJW70881.1 - 4.2e-06 26.5 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AJW70881.1 - 0.0007 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 AJW70881.1 - 0.0025 17.3 0.1 0.0063 16.0 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_33 PF13671.6 AJW70881.1 - 0.0064 16.7 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AJW70881.1 - 0.0078 16.5 0.2 0.016 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AJW70881.1 - 0.01 15.2 0.1 0.027 13.8 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_16 PF13191.6 AJW70881.1 - 0.013 15.9 0.2 0.022 15.2 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 AJW70881.1 - 0.015 15.9 0.7 0.038 14.5 0.6 1.8 1 1 0 1 1 1 0 AAA domain Rad51 PF08423.11 AJW70881.1 - 0.015 14.6 0.8 0.088 12.1 0.1 2.0 2 0 0 2 2 2 0 Rad51 DUF2075 PF09848.9 AJW70881.1 - 0.018 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 AJW70881.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 AJW70881.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 AJW70881.1 - 0.31 10.8 1.0 0.87 9.4 0.8 1.9 1 1 0 1 1 1 0 P-loop containing region of AAA domain Saccharop_dh_N PF04455.12 AJW70882.1 - 6.5e-34 116.3 0.3 2.1e-33 114.7 0.4 1.8 2 0 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region TPP_enzyme_M PF00205.22 AJW70882.1 - 0.0047 16.7 0.5 0.073 12.8 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DS PF01916.17 AJW70882.1 - 0.013 14.8 1.7 0.39 9.9 0.1 2.9 1 1 2 3 3 3 0 Deoxyhypusine synthase Citrate_bind PF16114.5 AJW70882.1 - 0.035 13.6 0.3 0.27 10.7 0.0 2.3 2 1 1 3 3 3 0 ATP citrate lyase citrate-binding PepSY_like PF11396.8 AJW70884.1 - 0.0089 16.6 2.1 0.016 15.8 0.4 2.0 1 1 1 2 2 2 1 Putative beta-lactamase-inhibitor-like, PepSY-like ArlS_N PF18719.1 AJW70884.1 - 0.025 14.8 2.2 0.025 14.8 2.2 1.6 2 0 0 2 2 2 0 ArlS sensor domain Phage_T7_tail PF03906.14 AJW70884.1 - 0.032 13.9 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Phage T7 tail fibre protein HD_3 PF13023.6 AJW70886.1 - 2e-39 135.1 3.7 2.3e-39 135.0 3.7 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AJW70886.1 - 2.6e-16 59.9 4.0 3.3e-16 59.5 4.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AJW70886.1 - 2e-05 24.8 0.1 8e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 HD domain DUF5056 PF16479.5 AJW70886.1 - 0.003 17.8 1.2 0.38 11.0 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5056) SKA2 PF16740.5 AJW70886.1 - 0.57 10.0 7.1 2.3 8.0 0.7 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Cob_adeno_trans PF01923.18 AJW70887.1 - 3.3e-54 183.4 0.0 3.7e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF1664 PF07889.12 AJW70888.1 - 0.014 15.4 3.4 0.016 15.2 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AJW70888.1 - 0.023 15.0 6.8 0.03 14.6 6.8 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCN5L1 PF06320.13 AJW70888.1 - 0.056 13.6 6.1 0.063 13.4 6.1 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Xrn1_D3 PF18194.1 AJW70888.1 - 0.06 13.4 2.3 0.088 12.9 2.3 1.4 1 1 0 1 1 1 0 Exoribonuclease 1 Domain-3 CR6_interact PF10147.9 AJW70888.1 - 0.077 12.7 6.0 0.086 12.5 6.0 1.0 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Erf4 PF10256.9 AJW70888.1 - 0.18 11.9 1.8 0.33 11.1 0.5 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Mt_ATP-synt_D PF05873.12 AJW70888.1 - 0.32 10.8 6.0 0.49 10.2 6.0 1.4 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) TMPIT PF07851.13 AJW70888.1 - 0.53 9.5 5.6 0.64 9.2 5.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 AJW70888.1 - 0.64 8.6 9.6 0.69 8.5 9.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF16 PF01519.16 AJW70888.1 - 1.6 9.2 8.9 3.2 8.3 8.9 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 GTP-bdg_M PF16360.5 AJW70888.1 - 7.5 7.2 6.9 57 4.4 6.7 2.1 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region HATPase_c PF02518.26 AJW70889.1 - 1.5e-19 70.5 0.4 4e-19 69.2 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW70889.1 - 3e-06 27.1 0.3 6.9e-06 26.0 0.3 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW70889.1 - 1.6e-05 24.7 0.0 1.6e-05 24.7 0.0 2.6 3 0 0 3 3 3 1 GHKL domain GvpK PF05121.12 AJW70889.1 - 0.0014 18.7 0.8 0.0049 16.9 0.8 2.0 1 0 0 1 1 1 1 Gas vesicle protein K HATPase_c_3 PF13589.6 AJW70889.1 - 0.0017 18.2 0.0 0.0017 18.2 0.0 2.8 3 1 1 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW70889.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Peptidase_A25 PF03418.14 AJW70889.1 - 2.6 6.8 12.8 1 8.2 9.8 1.7 1 1 1 2 2 2 0 Germination protease Atg14 PF10186.9 AJW70889.1 - 3.5 6.6 17.6 6.1 5.8 17.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Response_reg PF00072.24 AJW70890.1 - 1.3e-24 86.6 0.1 2.2e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain RNA_pol_Rpc82 PF05645.13 AJW70891.1 - 0.18 11.5 8.6 0.2 11.4 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 RNA_pol_Rpc4 PF05132.14 AJW70891.1 - 0.69 10.3 12.4 0.94 9.9 12.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2228 PF10228.9 AJW70891.1 - 1.7 8.3 8.0 1.9 8.1 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) PPL5 PF18168.1 AJW70891.1 - 2.5 7.3 7.9 2.7 7.2 7.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 FGF-BP1 PF06473.12 AJW70891.1 - 2.9 7.7 12.5 3.1 7.6 12.5 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Pneumo_att_G PF05539.11 AJW70891.1 - 5.6 6.5 11.9 6.4 6.3 11.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G IHABP4_N PF16174.5 AJW70891.1 - 9.5 6.8 16.0 11 6.5 16.0 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal PTPS PF01242.19 AJW70892.1 - 0.01 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase AsnC_trans_reg PF01037.21 AJW70892.1 - 0.012 15.6 0.3 0.017 15.1 0.3 1.3 1 1 0 1 1 1 0 Lrp/AsnC ligand binding domain AsnC_trans_reg PF01037.21 AJW70893.1 - 5e-06 26.4 0.1 5.5e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 AJW70893.1 - 0.0068 16.3 0.0 0.007 16.3 0.0 1.1 1 0 0 1 1 1 1 GYD domain Glyoxalase_2 PF12681.7 AJW70894.1 - 1.4e-09 37.8 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 AJW70894.1 - 3e-08 33.9 0.0 7.4e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AJW70894.1 - 0.00039 21.2 0.0 0.00046 20.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AJW70894.1 - 0.0047 17.2 0.0 0.14 12.4 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gly_acyl_tr_C PF08444.10 AJW70896.1 - 0.072 13.3 0.7 0.26 11.6 0.1 2.0 2 1 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Prp19 PF08606.11 AJW70897.1 - 0.0044 17.0 1.0 0.012 15.6 0.3 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like DivIC PF04977.15 AJW70897.1 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Septum formation initiator DUF2756 PF10956.8 AJW70897.1 - 0.041 14.4 4.0 0.085 13.4 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2756) Shugoshin_N PF07558.11 AJW70897.1 - 5.6 6.9 8.9 1.5 8.7 4.9 2.1 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region zf-PARP PF00645.18 AJW70898.1 - 0.015 16.2 1.0 0.015 16.1 1.0 1.0 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Guanylate_cyc PF00211.20 AJW70899.1 - 2.6e-17 63.0 0.1 3.6e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HTH_24 PF13412.6 AJW70900.1 - 0.061 12.9 0.2 20 4.8 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding GFRP PF06399.13 AJW70900.1 - 0.078 12.9 0.2 0.58 10.1 0.0 2.4 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) CPSase_L_D3 PF02787.19 AJW70900.1 - 0.23 11.8 2.3 0.49 10.7 0.7 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PALP PF00291.25 AJW70901.1 - 9e-86 287.9 0.4 1.7e-85 287.0 0.3 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 AJW70901.1 - 0.003 17.3 0.1 0.0073 16.1 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AJW70901.1 - 0.021 15.4 0.1 0.057 14.0 0.1 1.7 1 0 0 1 1 1 0 ACT domain AIRC PF00731.20 AJW70902.1 - 4.4e-59 198.3 0.5 5.6e-59 198.0 0.5 1.1 1 0 0 1 1 1 1 AIR carboxylase PrpR_N PF06506.11 AJW70902.1 - 0.013 15.1 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 Propionate catabolism activator Asp_Glu_race PF01177.22 AJW70902.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.5 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase ATP-grasp PF02222.22 AJW70903.1 - 1.2e-57 194.3 0.0 1.7e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AJW70903.1 - 1.8e-12 46.8 0.0 3.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AJW70903.1 - 3e-06 26.9 0.1 1.2e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AJW70903.1 - 9.3e-05 22.5 0.1 0.00021 21.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain DUF1297 PF06973.12 AJW70903.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) PglD_N PF17836.1 AJW70903.1 - 0.086 13.5 0.4 0.51 11.0 0.2 2.4 1 1 1 2 2 2 0 PglD N-terminal domain DUF4418 PF14387.6 AJW70904.1 - 0.87 9.8 5.1 0.43 10.8 2.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) NTP_transferase PF00483.23 AJW70907.1 - 9e-31 107.3 0.3 1.4e-30 106.7 0.3 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJW70907.1 - 4.6e-11 43.3 0.0 6.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJW70907.1 - 0.0073 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CspB_prodomain PF18425.1 AJW70907.1 - 0.03 14.3 0.8 0.077 13.0 0.0 1.9 2 0 0 2 2 2 0 Csp protease B prodomain Bac_luciferase PF00296.20 AJW70909.1 - 1.4e-58 198.8 0.0 1.5e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase AAA_lid_10 PF17872.1 AJW70909.1 - 0.21 11.7 3.2 0.26 11.5 0.5 2.3 3 0 0 3 3 3 0 AAA lid domain Thiolase_C PF02803.18 AJW70910.1 - 4.4e-12 45.7 0.1 1.3e-11 44.2 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 AJW70910.1 - 5.5e-11 42.3 0.7 1.5e-09 37.6 0.1 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 AJW70910.1 - 0.013 15.1 0.1 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 AJW70910.1 - 0.095 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF35_N PF12172.8 AJW70911.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2185 PF09951.9 AJW70913.1 - 0.0076 16.1 0.5 0.0076 16.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) Hjc PF01870.18 AJW70914.1 - 5.8e-05 23.0 0.0 0.00013 21.9 0.0 1.7 1 1 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) Pentapeptide PF00805.22 AJW70916.1 - 4.3e-30 102.9 11.7 1.3e-09 37.5 2.2 4.3 1 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AJW70916.1 - 2.8e-15 56.3 0.1 3.5e-08 33.5 0.0 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AJW70916.1 - 1.2e-10 41.4 1.3 0.00019 21.5 1.4 3.9 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Baculo_LEF-11 PF06385.12 AJW70917.1 - 0.0023 18.4 0.2 0.0075 16.7 0.1 1.9 2 0 0 2 2 2 1 Baculovirus LEF-11 protein DUF3278 PF11683.8 AJW70917.1 - 0.012 15.7 0.1 0.023 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) CorA PF01544.18 AJW70917.1 - 0.25 10.6 3.2 1.1 8.5 0.1 2.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein SesA PF17107.5 AJW70918.1 - 0.0017 18.5 1.0 0.0021 18.2 1.0 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases GIT1_C PF12205.8 AJW70918.1 - 0.0024 17.9 0.1 0.0029 17.7 0.1 1.1 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term LidA_Long_CC PF18641.1 AJW70918.1 - 0.016 15.3 2.0 3 7.9 1.2 2.1 2 0 0 2 2 2 0 LidA long coiled-coil domain YtxH PF12732.7 AJW70918.1 - 0.035 14.6 2.6 0.99 10.0 0.0 2.2 2 0 0 2 2 2 0 YtxH-like protein Agarase_CBM PF17992.1 AJW70920.1 - 0.0059 16.2 0.3 0.0098 15.5 0.1 1.5 1 1 0 1 1 1 1 Agarase CBM like domain PALP PF00291.25 AJW70921.1 - 8.3e-46 156.7 0.0 1e-45 156.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF21 PF01595.20 AJW70922.1 - 5.1e-50 169.6 0.1 7.2e-50 169.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AJW70922.1 - 1.5e-16 60.2 1.1 1.5e-16 60.2 1.1 2.4 1 1 1 2 2 2 1 Transporter associated domain CBS PF00571.28 AJW70922.1 - 1e-14 54.7 0.9 1.1e-06 28.9 0.1 2.7 2 0 0 2 2 2 2 CBS domain DapB_N PF01113.20 AJW70923.1 - 0.0029 17.7 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 AJW70923.1 - 0.027 14.8 0.0 0.18 12.1 0.0 2.4 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AJW70923.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ATP-synt PF00231.19 AJW70924.1 - 0.069 12.9 0.0 0.078 12.7 0.0 1.0 1 0 0 1 1 1 0 ATP synthase Glycos_transf_2 PF00535.26 AJW70925.1 - 1.3e-33 116.2 0.1 2.8e-33 115.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJW70925.1 - 3.6e-31 108.8 0.0 5e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AJW70925.1 - 1.1e-25 90.7 0.1 1.1e-25 90.7 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 AJW70925.1 - 1e-13 50.8 1.0 7.4e-10 38.0 0.1 3.2 3 0 0 3 3 3 2 Chitin synthase Glyco_transf_21 PF13506.6 AJW70925.1 - 8.9e-11 41.6 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 AJW70925.1 - 3.1e-10 40.0 0.1 5.7e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AJW70925.1 - 0.003 18.1 0.0 0.0078 16.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF2207 PF09972.9 AJW70925.1 - 0.11 11.2 8.7 0.1 11.4 3.8 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Polysacc_deac_1 PF01522.21 AJW70926.1 - 2e-09 37.4 0.0 3.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 AJW70926.1 - 5.1e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 AJW70926.1 - 0.0001 21.6 0.0 0.00029 20.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 SdrD_B PF17210.3 AJW70926.1 - 0.00016 21.9 0.8 0.22 11.7 0.1 2.6 1 1 0 2 2 2 2 SdrD B-like domain CarboxypepD_reg PF13620.6 AJW70926.1 - 0.00036 20.7 0.1 0.41 11.0 0.0 2.5 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain DUF5119 PF17145.4 AJW70926.1 - 0.0017 18.4 2.7 0.47 10.4 0.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5119) DUF2012 PF09430.10 AJW70926.1 - 0.0037 17.4 0.1 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) DUF2334 PF10096.9 AJW70927.1 - 1.3e-05 25.0 3.1 4.5e-05 23.2 1.3 2.7 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 AJW70927.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase TrbH PF07283.11 AJW70927.1 - 0.0034 17.6 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 Conjugal transfer protein TrbH IucA_IucC PF04183.12 AJW70927.1 - 0.022 14.3 0.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 IucA / IucC family Sigma54_CBD PF04963.13 AJW70927.1 - 0.041 13.7 2.8 1.3 8.9 0.1 3.4 4 0 0 4 4 4 0 Sigma-54 factor, core binding domain AP_endonuc_2 PF01261.24 AJW70927.1 - 0.087 12.2 0.0 0.94 8.9 0.0 2.5 3 1 1 4 4 4 0 Xylose isomerase-like TIM barrel Gag_MA PF01140.19 AJW70927.1 - 0.19 11.5 4.4 6 6.6 0.4 2.4 1 1 1 2 2 2 0 Matrix protein (MA), p15 TackOD1 PF18551.1 AJW70928.1 - 7.3e-31 107.3 16.1 1.2e-30 106.6 16.1 1.3 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 Response_reg PF00072.24 AJW70928.1 - 3.4e-18 65.8 0.2 6.2e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain zinc-ribbons_6 PF07191.12 AJW70928.1 - 7.9e-05 22.6 17.1 0.012 15.6 6.1 2.9 1 1 2 3 3 3 3 zinc-ribbons HTH_5 PF01022.20 AJW70928.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TFA2_Winged_2 PF18121.1 AJW70928.1 - 0.0041 16.8 0.1 1.4 8.6 0.1 2.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 DZR PF12773.7 AJW70928.1 - 0.0059 16.6 16.6 0.27 11.3 8.8 2.8 1 1 2 3 3 3 3 Double zinc ribbon BLACT_WH PF17778.1 AJW70928.1 - 0.0086 16.0 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain TrmB PF01978.19 AJW70928.1 - 0.01 15.7 0.2 0.046 13.6 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 AJW70928.1 - 0.02 15.1 0.1 0.059 13.6 0.1 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain zf-Di19 PF05605.12 AJW70928.1 - 0.024 14.9 10.4 0.029 14.6 2.9 2.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 AJW70928.1 - 0.087 13.6 0.6 0.087 13.6 0.6 3.4 2 1 1 3 3 2 0 zinc-ribbon family AAA PF00004.29 AJW70928.1 - 0.14 12.6 1.5 0.47 10.9 0.8 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zn_Tnp_IS1595 PF12760.7 AJW70928.1 - 0.18 11.8 10.8 0.3 11.1 0.4 3.7 4 0 0 4 4 4 0 Transposase zinc-ribbon domain HTH_20 PF12840.7 AJW70928.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HypA PF01155.19 AJW70928.1 - 0.25 11.4 17.5 0.094 12.7 2.1 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ZZ PF00569.17 AJW70928.1 - 0.33 10.8 15.6 3.7 7.4 3.3 3.6 3 0 0 3 3 3 0 Zinc finger, ZZ type Zn-ribbon_8 PF09723.10 AJW70928.1 - 0.89 9.7 19.7 11 6.2 0.1 5.1 3 2 2 5 5 5 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 AJW70928.1 - 1.9 8.4 16.0 12 5.8 0.7 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cytochrom_c3_2 PF14537.6 AJW70928.1 - 5.8 7.4 15.6 1.7 9.1 0.9 2.9 2 1 0 2 2 2 0 Cytochrome c3 zf_UBZ PF18439.1 AJW70928.1 - 6.9 6.4 18.3 14 5.4 0.1 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger HscB_4_cys PF18256.1 AJW70928.1 - 9 6.2 6.5 2.6 8.0 2.0 2.2 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif MG2 PF01835.19 AJW70929.1 - 0.00068 20.0 0.2 0.0014 19.0 0.1 1.7 2 1 0 2 2 2 1 MG2 domain Thioredoxin_4 PF13462.6 AJW70930.1 - 1.2e-30 106.9 0.0 1.4e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJW70930.1 - 4.1e-17 62.6 0.1 7.8e-16 58.4 0.1 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJW70930.1 - 3.1e-05 24.4 0.0 6.5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AJW70930.1 - 0.11 12.9 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like HMG_CoA_synt_C PF08540.10 AJW70931.1 - 4e-34 118.5 0.1 6e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 AJW70931.1 - 4.8e-30 104.7 0.2 7.7e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal L31 PF09784.9 AJW70933.1 - 0.14 12.6 0.3 0.29 11.6 0.3 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 SDF PF00375.18 AJW70934.1 - 5.6e-111 371.3 43.0 6.3e-111 371.1 43.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family TMEM100 PF16311.5 AJW70934.1 - 0.072 12.7 2.4 0.2 11.3 2.4 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 Baculo_E56 PF04639.12 AJW70934.1 - 2.2 7.5 6.6 5.1 6.3 5.5 2.2 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope AAA_26 PF13500.6 AJW70935.1 - 1.2e-40 139.5 0.1 1.4e-40 139.3 0.1 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AJW70935.1 - 7.2e-12 45.5 0.0 1.1e-11 44.8 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 AJW70935.1 - 0.00017 20.9 0.4 0.045 13.0 0.5 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF1611_C) P-loop domain ParA PF10609.9 AJW70935.1 - 0.0014 18.1 4.5 0.041 13.3 4.5 2.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Secretin PF00263.21 AJW70935.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Aminotran_3 PF00202.21 AJW70936.1 - 3.4e-105 352.0 0.0 4.2e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AJW70936.1 - 0.0019 17.5 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Radical_SAM PF04055.21 AJW70937.1 - 1.4e-19 71.1 0.7 2.8e-19 70.1 0.7 1.5 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.13 AJW70937.1 - 2.3e-10 40.5 0.0 4.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain MRP-S28 PF10213.9 AJW70937.1 - 0.05 14.0 0.2 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein DUF5420 PF17457.2 AJW70937.1 - 0.12 12.2 0.5 0.21 11.4 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5420) HhH-GPD PF00730.25 AJW70937.1 - 0.14 12.7 0.1 7.5 7.1 0.0 2.4 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein zf-HC5HC2H PF13771.6 AJW70937.1 - 2.1 8.7 5.6 2.6 8.4 0.4 2.5 2 1 0 2 2 2 0 PHD-like zinc-binding domain DsbD PF02683.15 AJW70938.1 - 1.1e-49 169.2 19.1 1.3e-49 169.0 19.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AJW70938.1 - 4.1e-07 30.1 15.1 5.4e-07 29.7 15.1 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region SfLAP PF11139.8 AJW70938.1 - 0.086 12.3 14.4 0.0076 15.7 7.9 2.3 2 1 0 2 2 2 0 Sap, sulfolipid-1-addressing protein DUF4112 PF13430.6 AJW70938.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4112) Claudin_2 PF13903.6 AJW70938.1 - 0.35 10.6 12.1 0.023 14.4 3.3 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2781 PF10914.8 AJW70938.1 - 0.81 10.1 5.3 0.43 11.0 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) DUF373 PF04123.13 AJW70938.1 - 4.2 6.7 12.5 5.5 6.3 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Thioredoxin_10 PF17991.1 AJW70939.1 - 1.1e-34 120.0 0.0 1.8e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin like C-terminal domain AhpC-TSA PF00578.21 AJW70939.1 - 4.6e-08 33.0 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJW70939.1 - 1.5e-07 31.2 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AJW70939.1 - 0.018 15.3 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like DUF2744 PF10910.8 AJW70939.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) Snf7 PF03357.21 AJW70940.1 - 1e-06 28.4 0.7 1.7e-06 27.7 0.7 1.3 1 0 0 1 1 1 1 Snf7 Cu-oxidase_2 PF07731.14 AJW70941.1 - 9e-17 61.1 11.9 9.9e-12 44.8 6.9 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 AJW70941.1 - 3.5e-10 39.9 5.0 1.1e-06 28.7 0.2 3.0 2 1 0 2 2 2 2 Multicopper oxidase Copper-bind PF00127.20 AJW70941.1 - 0.0045 17.4 0.5 0.21 12.0 0.1 2.6 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family TPK_B1_binding PF04265.14 AJW70942.1 - 0.016 14.9 0.0 0.12 12.1 0.0 2.3 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, vitamin B1 binding domain WbqC PF08889.11 AJW70942.1 - 0.074 12.9 1.0 0.11 12.4 0.8 1.4 1 1 0 1 1 1 0 WbqC-like protein family DUF371 PF04027.13 AJW70944.1 - 6.9e-46 155.5 0.0 7.6e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) Proteasome PF00227.26 AJW70946.1 - 1.8e-54 184.1 0.5 2.4e-54 183.7 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 AJW70946.1 - 3.4e-14 52.2 0.7 1.4e-13 50.2 0.1 2.3 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltrn_RNA_3 PF02598.17 AJW70947.1 - 1.6e-52 178.8 0.0 1.8e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 AJW70947.1 - 0.01 16.0 0.0 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 SpoU rRNA Methylase family LSDAT_prok PF18171.1 AJW70947.1 - 0.036 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote DDDD PF10161.9 AJW70948.1 - 0.057 13.2 0.0 0.069 12.9 0.0 1.0 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Ribosomal_L3 PF00297.22 AJW70949.1 - 6.9e-71 239.2 3.0 4.5e-70 236.5 3.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L4 PF00573.22 AJW70950.1 - 2.4e-42 144.8 0.1 2.8e-42 144.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.20 AJW70951.1 - 8.2e-15 55.0 2.6 1.5e-14 54.1 2.6 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.19 AJW70951.1 - 0.0016 18.1 0.1 0.0025 17.5 0.1 1.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain NOP5NT PF08156.13 AJW70951.1 - 0.016 15.6 0.3 0.025 14.9 0.2 1.4 1 1 0 1 1 1 0 NOP5NT (NUC127) domain Ribosomal_S19 PF00203.21 AJW70952.1 - 4.3e-28 97.0 0.6 5.4e-28 96.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L22 PF00237.19 AJW70953.1 - 6.7e-25 87.3 1.0 9.1e-25 86.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.20 AJW70954.1 - 2.7e-19 69.4 1.6 2.7e-19 69.4 1.6 1.9 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AJW70954.1 - 8.8e-13 47.9 0.2 2.8e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 AJW70954.1 - 0.014 15.3 0.0 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 KH domain Ribosomal_L29 PF00831.23 AJW70955.1 - 5.7e-12 45.4 4.8 7.2e-12 45.1 4.8 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein UPF0086 PF01868.16 AJW70956.1 - 9.7e-19 67.1 0.0 1.1e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_S17 PF00366.20 AJW70957.1 - 3.2e-16 59.2 0.3 4.1e-16 58.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 AJW70957.1 - 8.1e-06 26.1 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_L14 PF00238.19 AJW70958.1 - 8.5e-33 113.0 0.8 9.6e-33 112.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L26 PF16906.5 AJW70959.1 - 2.2e-15 56.9 0.5 3.5e-15 56.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 AJW70959.1 - 1.5e-05 24.8 0.5 3.8e-05 23.5 0.5 1.7 1 0 0 1 1 1 1 KOW motif Ribosomal_S4e PF00900.20 AJW70960.1 - 8.3e-20 70.5 0.4 2.1e-19 69.2 0.4 1.7 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 AJW70960.1 - 7.5e-13 48.4 1.4 1.3e-12 47.6 1.4 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 AJW70960.1 - 0.00066 19.3 0.1 0.002 17.8 0.1 1.9 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 AJW70960.1 - 0.02 14.9 1.5 0.037 14.0 0.3 2.2 2 0 0 2 2 2 0 KOW motif Ribosomal_L5_C PF00673.21 AJW70961.1 - 2.3e-21 75.7 0.0 4.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AJW70961.1 - 1.9e-12 47.3 0.3 3.4e-12 46.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S14 PF00253.21 AJW70962.1 - 1.7e-08 34.1 3.3 2.3e-08 33.7 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.14 AJW70962.1 - 0.036 13.9 2.6 0.068 13.0 2.3 1.6 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Ribosomal_S8 PF00410.19 AJW70963.1 - 5.2e-21 74.9 0.0 6.1e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 ID PF18543.1 AJW70963.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Intracellular delivery domain Ribosomal_L6 PF00347.23 AJW70964.1 - 1.5e-10 41.6 4.8 0.0002 22.0 1.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 CPT_N PF16484.5 AJW70964.1 - 0.19 11.8 0.0 23 5.1 0.0 3.0 3 0 0 3 3 3 0 Carnitine O-palmitoyltransferase N-terminus DZR PF12773.7 AJW70966.1 - 0.00042 20.3 0.2 0.00055 19.9 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF35_N PF12172.8 AJW70966.1 - 0.0078 16.1 1.2 1.1 9.2 0.0 2.4 2 1 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 AJW70966.1 - 0.0093 16.1 0.1 0.4 10.8 0.0 2.2 2 0 0 2 2 2 1 Zinc ribbon domain C1_4 PF07975.12 AJW70966.1 - 0.015 15.5 1.6 0.62 10.3 2.3 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain DNA_RNApol_7kD PF03604.13 AJW70966.1 - 0.021 14.5 1.5 1.1 9.0 0.4 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.12 AJW70966.1 - 0.048 13.5 1.5 2.3 8.1 0.2 2.4 2 0 0 2 2 2 0 HypF finger zf-LYAR PF08790.11 AJW70966.1 - 0.11 12.4 1.6 8.9 6.3 0.2 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-IS66 PF13005.7 AJW70966.1 - 0.24 11.8 5.3 0.36 11.3 0.2 2.6 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn_ribbon_SprT PF17283.2 AJW70966.1 - 0.51 10.3 4.1 3.7 7.5 3.6 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DUF4257 PF14074.6 AJW70967.1 - 0.028 14.6 1.6 0.043 14.0 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4257) Phage_holin_5_2 PF16079.5 AJW70967.1 - 0.08 13.3 5.5 1.8 8.9 4.2 2.0 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF2407_C PF13373.6 AJW70967.1 - 0.11 12.7 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF3899 PF13038.6 AJW70967.1 - 0.13 12.8 3.1 3.9 8.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF2207 PF09972.9 AJW70967.1 - 1.1 8.0 4.6 1.6 7.4 4.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4342 PF14242.6 AJW70967.1 - 7.4 6.6 6.0 13 5.9 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4342) DUF2299 PF10061.9 AJW70968.1 - 6e-22 77.9 1.6 7.2e-22 77.6 1.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) DUF1850 PF08905.11 AJW70969.1 - 0.061 13.7 0.0 0.065 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) DUF2279 PF10043.9 AJW70971.1 - 0.057 14.2 0.1 0.2 12.4 0.0 1.8 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) DUF4352 PF11611.8 AJW70972.1 - 1.1e-11 45.1 1.0 1.3e-11 44.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) tRNA_deacylase PF04414.12 AJW70972.1 - 0.011 15.3 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase S1FA PF04689.13 AJW70972.1 - 0.093 12.9 0.8 0.16 12.2 0.8 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA MacB_PCD PF12704.7 AJW70972.1 - 0.21 11.9 1.9 0.82 10.0 1.9 1.8 1 1 0 1 1 1 0 MacB-like periplasmic core domain Putative_PNPOx PF01243.20 AJW70974.1 - 1.2e-15 57.4 0.0 1.7e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJW70974.1 - 0.00078 19.5 0.0 0.0014 18.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RcnB PF11776.8 AJW70974.1 - 0.1 12.7 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator SNCAIP_SNCA_bd PF16700.5 AJW70975.1 - 0.036 13.8 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain HTH_20 PF12840.7 AJW70976.1 - 7.6e-09 35.5 0.2 1.3e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AJW70976.1 - 1.2e-06 28.3 0.4 9.2e-06 25.4 0.4 2.2 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.10 AJW70976.1 - 1.5e-05 24.9 0.3 2.7e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain FUR PF01475.19 AJW70976.1 - 0.00033 20.8 0.7 0.00069 19.7 0.7 1.6 1 1 0 1 1 1 1 Ferric uptake regulator family Replic_Relax PF13814.6 AJW70976.1 - 0.0017 18.4 0.4 0.0056 16.8 0.1 1.9 2 0 0 2 2 2 1 Replication-relaxation TFIIE_alpha PF02002.17 AJW70976.1 - 0.0085 15.9 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 TFIIE alpha subunit Type2_restr_D3 PF16902.5 AJW70976.1 - 0.017 15.0 0.1 0.043 13.7 0.1 1.7 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain HTH_32 PF13565.6 AJW70976.1 - 0.061 13.9 0.0 0.2 12.3 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DUF5300 PF17224.3 AJW70978.1 - 0.00034 20.8 0.0 0.00049 20.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5300) Response_reg PF00072.24 AJW70979.1 - 6.3e-20 71.4 0.2 7.1e-20 71.2 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain eRF1_2 PF03464.15 AJW70979.1 - 0.033 14.5 0.3 0.052 13.9 0.2 1.4 1 1 0 1 1 1 0 eRF1 domain 2 HATPase_c PF02518.26 AJW70980.1 - 2.1e-26 92.6 0.3 6.1e-26 91.1 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MASE3 PF17159.4 AJW70980.1 - 9.4e-13 48.3 19.0 9.4e-13 48.3 19.0 1.4 2 0 0 2 2 2 1 Membrane-associated sensor domain PAS_9 PF13426.7 AJW70980.1 - 4.5e-12 46.1 0.3 1.3e-11 44.7 0.3 1.7 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 AJW70980.1 - 1.5e-11 44.2 0.1 1.3e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AJW70980.1 - 5.1e-11 42.6 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AJW70980.1 - 4.4e-08 33.3 0.8 7.6e-08 32.5 0.3 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AJW70980.1 - 5.3e-06 26.7 0.0 9.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AJW70980.1 - 5.7e-05 23.0 0.3 0.00017 21.4 0.3 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AJW70980.1 - 0.00014 21.7 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AJW70980.1 - 0.0093 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain Tai4 PF16695.5 AJW70980.1 - 0.036 14.6 0.1 0.64 10.6 0.1 2.4 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein NTP_transf_9 PF04248.12 AJW70981.1 - 7.9e-32 109.0 0.6 8.7e-32 108.9 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DAHP_synth_1 PF00793.20 AJW70981.1 - 0.17 10.7 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family GATase_6 PF13522.6 AJW70982.1 - 7.2e-14 52.1 0.0 1e-12 48.4 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AJW70982.1 - 1.6e-13 50.7 0.0 1.2e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AJW70982.1 - 7.8e-10 38.5 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AJW70982.1 - 1.4e-05 24.1 0.0 2.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 AJW70982.1 - 0.00036 19.4 0.0 0.039 12.7 0.0 2.8 3 0 0 3 3 3 1 Glutamine amidotransferases class-II RQC PF09382.10 AJW70982.1 - 0.019 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 RQC domain Dip PF17679.1 AJW70982.1 - 0.028 14.0 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 gp37/Dip protein DUF3919 PF13057.6 AJW70982.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Pribosyltran_N PF13793.6 AJW70982.1 - 0.14 12.1 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase AIRS_C PF02769.22 AJW70983.1 - 9.6e-44 149.2 0.5 2.7e-28 99.1 0.5 2.2 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AJW70983.1 - 6.8e-38 129.2 0.1 2.9e-18 66.3 0.3 2.8 3 0 0 3 3 3 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 AJW70983.1 - 7.4e-11 42.4 0.4 1.7e-10 41.3 0.4 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Orn_Arg_deC_N PF02784.16 AJW70983.1 - 0.21 10.9 3.7 2.9 7.2 0.2 2.3 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain GATase_5 PF13507.6 AJW70984.1 - 2.1e-41 141.7 0.0 6.1e-41 140.2 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AJW70984.1 - 1.4e-09 38.0 0.0 2.4e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AJW70984.1 - 2.5e-09 37.0 0.0 1.1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AJW70984.1 - 2.7e-07 30.5 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 AJW70984.1 - 0.0016 18.2 0.2 0.0037 17.1 0.2 1.6 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJW70984.1 - 0.043 13.7 0.0 0.09 12.6 0.0 1.5 2 0 0 2 2 2 0 SNO glutamine amidotransferase family PurS PF02700.14 AJW70985.1 - 6.9e-19 67.8 0.6 7.6e-19 67.7 0.6 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase Ribosomal_L12_N PF16320.5 AJW70988.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain TatC PF00902.18 AJW70989.1 - 4.6e-52 176.9 13.8 5.4e-52 176.6 13.8 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) MttA_Hcf106 PF02416.16 AJW70990.1 - 8.8e-09 34.6 6.8 5e-08 32.1 6.8 2.0 1 1 0 1 1 1 1 mttA/Hcf106 family DUF4179 PF13786.6 AJW70990.1 - 0.09 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Polyketide_cyc PF03364.20 AJW70991.1 - 0.00024 21.3 0.0 0.00092 19.4 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AJW70991.1 - 0.0042 17.4 0.0 0.0063 16.8 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Flavoprotein PF02441.19 AJW70992.1 - 8.5e-30 103.6 0.2 1e-29 103.3 0.2 1.0 1 0 0 1 1 1 1 Flavoprotein DUF3672 PF12421.8 AJW70992.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin type III protein DUF1297 PF06973.12 AJW70994.1 - 1.2e-72 243.4 0.1 1.7e-72 242.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 AJW70994.1 - 1e-47 161.1 0.0 2e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) zf-trcl PF13451.6 AJW70996.1 - 0.0004 20.2 0.2 0.043 13.7 0.0 2.1 2 0 0 2 2 2 2 Probable zinc-ribbon domain Lar_restr_allev PF14354.6 AJW70996.1 - 0.0034 17.7 0.1 0.0042 17.4 0.1 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-RRPl_C4 PF17026.5 AJW70996.1 - 0.038 14.1 0.8 0.054 13.6 0.8 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-FPG_IleRS PF06827.14 AJW70996.1 - 0.05 13.5 1.4 1.1 9.2 0.3 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.6 AJW70996.1 - 0.15 12.0 2.0 0.39 10.7 2.0 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Lentiviral_Tat PF02998.14 AJW70997.1 - 0.07 13.2 0.3 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Lentiviral Tat protein DUF3444 PF11926.8 AJW70998.1 - 0.029 14.0 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) Mt_ATP-synt_D PF05873.12 AJW70999.1 - 0.0031 17.4 2.9 0.0035 17.2 2.9 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TMPIT PF07851.13 AJW70999.1 - 0.0042 16.4 0.5 0.0046 16.3 0.5 1.0 1 0 0 1 1 1 1 TMPIT-like protein HR1 PF02185.16 AJW70999.1 - 0.0075 16.4 0.6 0.0091 16.1 0.6 1.1 1 0 0 1 1 1 1 Hr1 repeat Cdh1_DBD_1 PF18196.1 AJW70999.1 - 0.0097 16.2 0.7 0.011 16.1 0.7 1.0 1 0 0 1 1 1 1 Chromodomain helicase DNA-binding domain 1 FlaC_arch PF05377.11 AJW70999.1 - 0.0099 16.2 1.6 0.1 13.0 0.2 2.1 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) FlxA PF14282.6 AJW70999.1 - 0.011 15.7 1.6 0.016 15.2 1.6 1.2 1 0 0 1 1 1 0 FlxA-like protein Snapin_Pallidin PF14712.6 AJW70999.1 - 0.037 14.4 1.7 0.048 14.1 1.7 1.1 1 0 0 1 1 1 0 Snapin/Pallidin DUF1192 PF06698.11 AJW70999.1 - 0.039 14.0 1.0 0.094 12.8 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) MtrG PF04210.13 AJW70999.1 - 0.14 12.0 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DNase-RNase PF02577.14 AJW71001.1 - 1e-06 28.4 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease TrkH PF02386.16 AJW71002.1 - 4.6e-19 68.2 26.4 5e-15 54.9 7.7 2.3 1 1 1 2 2 2 2 Cation transport protein CBS PF00571.28 AJW71002.1 - 1e-16 61.1 5.1 2.7e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 CBS domain Herpes_UL49_5 PF05702.11 AJW71003.1 - 7.6 6.7 7.0 1.3 9.2 0.2 2.8 2 1 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein DUF4576 PF15144.6 AJW71004.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) HTH_11 PF08279.12 AJW71006.1 - 0.012 15.5 0.3 0.11 12.5 0.3 2.4 1 1 0 1 1 1 0 HTH domain SLATT_6 PF18169.1 AJW71006.1 - 0.028 14.0 3.4 0.033 13.8 2.6 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 FUR PF01475.19 AJW71006.1 - 0.03 14.5 3.1 0.14 12.3 3.1 2.0 1 1 0 1 1 1 0 Ferric uptake regulator family Sec34 PF04136.15 AJW71006.1 - 0.041 13.8 3.2 0.17 11.7 3.2 2.0 1 1 0 1 1 1 0 Sec34-like family Prefoldin_2 PF01920.20 AJW71006.1 - 0.11 12.5 3.6 1 9.4 1.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit HTH_24 PF13412.6 AJW71006.1 - 0.21 11.2 2.5 0.3 10.7 0.8 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PhoU PF01895.19 AJW71006.1 - 0.76 10.3 4.9 0.81 10.2 0.5 2.8 2 1 1 3 3 3 0 PhoU domain DUF5615 PF18480.1 AJW71007.1 - 2.5e-14 52.8 0.2 6.9e-14 51.4 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5615) Mut7-C PF01927.16 AJW71007.1 - 2.4e-07 30.9 0.1 2.6e-07 30.9 0.1 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain PIN_10 PF18478.1 AJW71007.1 - 1.9e-06 28.0 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 PIN like domain PIN_9 PF18477.1 AJW71007.1 - 0.0013 19.0 0.0 0.0016 18.7 0.0 1.2 1 0 0 1 1 1 1 PIN like domain UPF0180 PF03698.13 AJW71007.1 - 0.0045 17.1 0.2 0.0066 16.6 0.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0180) DUF4411 PF14367.6 AJW71007.1 - 0.029 14.3 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) PIN PF01850.21 AJW71007.1 - 0.032 14.7 0.0 0.052 14.0 0.0 1.4 2 0 0 2 2 2 0 PIN domain DUF562 PF04763.12 AJW71007.1 - 0.043 13.3 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF562) PTS_IIB PF02302.17 AJW71007.1 - 0.12 13.1 0.1 1.5 9.6 0.1 2.1 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit DUF507 PF04368.13 AJW71008.1 - 0.022 14.7 5.9 0.026 14.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DUF1911 PF08929.10 AJW71008.1 - 0.034 14.9 0.6 0.034 14.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Histone_HNS PF00816.21 AJW71008.1 - 0.056 14.3 0.8 0.056 14.3 0.8 1.4 2 0 0 2 2 2 0 H-NS histone family Wbp11 PF09429.10 AJW71008.1 - 0.32 11.4 7.0 0.45 10.9 7.0 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 PV-1 PF06637.11 AJW71010.1 - 0.059 12.2 0.1 0.073 11.9 0.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Sulphotransf PF09037.10 AJW71011.1 - 0.02 14.4 0.1 0.029 13.9 0.1 1.4 1 1 0 1 1 1 0 Stf0 sulphotransferase AvrL567-A PF11529.8 AJW71011.1 - 0.079 13.2 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A Methyltransf_3 PF01596.17 AJW71012.1 - 9e-32 110.0 1.3 1.1e-31 109.7 1.3 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 AJW71012.1 - 8.5e-14 52.5 0.0 1.2e-13 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AJW71012.1 - 2.1e-08 34.2 0.0 2.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 AJW71012.1 - 0.00027 20.6 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 AJW71012.1 - 0.0006 19.6 0.1 0.00087 19.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PFK PF00365.20 AJW71012.1 - 0.013 14.9 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 0 Phosphofructokinase ATP-synt_F PF01990.17 AJW71012.1 - 0.016 15.5 2.3 0.48 10.8 1.4 2.3 1 1 1 2 2 2 0 ATP synthase (F/14-kDa) subunit Methyltransf_4 PF02390.17 AJW71012.1 - 0.019 14.4 0.8 0.079 12.4 0.1 2.2 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_15 PF09445.10 AJW71012.1 - 0.03 13.9 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 AJW71012.1 - 0.038 14.7 0.0 0.069 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.12 AJW71012.1 - 0.079 12.6 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF2530 PF10745.9 AJW71014.1 - 0.017 15.3 2.2 0.023 14.9 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) BCLP PF12304.8 AJW71014.1 - 0.13 11.8 1.3 0.16 11.5 1.3 1.2 1 0 0 1 1 1 0 Beta-casein like protein DUF3188 PF11384.8 AJW71014.1 - 5.1 6.9 8.3 2.5 7.9 1.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) PGPGW PF09656.10 AJW71014.1 - 8.8 5.9 9.3 9 5.9 1.0 2.1 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Syntaxin_2 PF14523.6 AJW71015.1 - 0.011 16.1 0.8 0.026 14.9 0.2 1.7 1 1 1 2 2 2 0 Syntaxin-like protein SpecificRecomb PF10136.9 AJW71015.1 - 0.12 10.7 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase Glycoprot_B_PH2 PF17417.2 AJW71017.1 - 0.00021 21.5 0.0 0.00027 21.2 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B PH-like domain DUF3244 PF11589.8 AJW71017.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Penicillinase_R PF03965.16 AJW71018.1 - 0.002 18.5 0.7 0.0095 16.3 0.2 1.9 1 1 1 2 2 2 1 Penicillinase repressor DUF4390 PF14334.6 AJW71018.1 - 0.024 14.1 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) Na_Ca_ex_C PF16494.5 AJW71018.1 - 0.14 12.6 2.8 0.26 11.8 1.0 2.0 1 1 1 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain HEAT_UF PF18817.1 AJW71018.1 - 0.17 12.2 1.6 0.98 9.7 0.1 2.7 3 1 0 3 3 3 0 Repeat of uncharacterized protein PH0542 TackOD1 PF18551.1 AJW71019.1 - 7.9e-30 103.9 9.1 1.1e-29 103.4 9.1 1.2 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 Response_reg PF00072.24 AJW71019.1 - 2.4e-10 40.6 0.0 4.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DZR PF12773.7 AJW71019.1 - 0.0035 17.3 13.3 0.27 11.3 7.4 2.8 1 1 2 3 3 3 3 Double zinc ribbon HTH_24 PF13412.6 AJW71019.1 - 0.005 16.4 0.7 0.02 14.5 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding zf-Di19 PF05605.12 AJW71019.1 - 0.0087 16.3 3.0 0.0087 16.3 3.0 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding FaeA PF04703.12 AJW71019.1 - 0.02 15.3 0.1 0.037 14.4 0.1 1.4 1 0 0 1 1 1 0 FaeA-like protein FeoC PF09012.10 AJW71019.1 - 0.022 14.8 0.8 0.022 14.8 0.8 3.1 4 0 0 4 4 4 0 FeoC like transcriptional regulator HypA PF01155.19 AJW71019.1 - 0.03 14.3 13.7 0.4 10.7 0.2 3.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 AJW71019.1 - 0.033 14.2 13.3 0.083 12.9 2.7 2.9 1 1 2 3 3 3 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 AJW71019.1 - 0.06 13.3 10.1 0.5 10.4 0.1 3.6 2 2 1 3 3 3 0 Transposase zinc-ribbon domain HTH_36 PF13730.6 AJW71019.1 - 0.061 13.3 0.5 0.18 11.7 0.5 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Spt4 PF06093.13 AJW71019.1 - 0.096 12.8 4.6 1.7 8.8 0.1 2.7 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger HTH_45 PF14947.6 AJW71019.1 - 0.25 11.4 2.5 0.28 11.2 0.1 2.3 3 0 0 3 3 2 0 Winged helix-turn-helix zf_UBZ PF18439.1 AJW71019.1 - 0.69 9.6 15.0 7.2 6.3 0.1 4.8 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger FYVE_2 PF02318.16 AJW71019.1 - 1.2 9.4 13.9 5.4 7.3 3.8 3.3 2 1 1 3 3 3 0 FYVE-type zinc finger Gin PF10764.9 AJW71019.1 - 2.8 8.0 11.1 5 7.2 0.2 3.7 2 1 1 3 3 3 0 Inhibitor of sigma-G Gin Evr1_Alr PF04777.13 AJW71019.1 - 3.2 8.3 4.8 19 5.8 0.1 2.9 2 1 1 3 3 3 0 Erv1 / Alr family PhnA_Zn_Ribbon PF08274.12 AJW71019.1 - 4.2 7.4 15.6 16 5.6 1.0 4.7 4 1 0 4 4 4 0 PhnA Zinc-Ribbon Endonuclease_7 PF02945.15 AJW71019.1 - 8.5 6.4 7.0 1.2e+02 2.7 7.0 2.5 1 1 0 1 1 1 0 Recombination endonuclease VII zinc_ribbon_15 PF17032.5 AJW71019.1 - 9.7 7.0 14.8 1.5 9.6 1.4 3.0 2 1 0 2 2 2 0 zinc-ribbon family Cnn_1N PF07989.11 AJW71020.1 - 0.00081 19.5 5.3 0.00082 19.5 5.3 1.0 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 AJW71020.1 - 0.00091 19.6 2.6 0.00097 19.5 2.6 1.1 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Leu_zip PF15294.6 AJW71020.1 - 0.0077 15.8 4.3 0.0077 15.8 4.3 1.0 1 0 0 1 1 1 1 Leucine zipper TMF_DNA_bd PF12329.8 AJW71020.1 - 0.0077 16.2 6.8 0.0083 16.1 6.8 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding IFP_35_N PF07334.13 AJW71020.1 - 0.0097 16.0 4.3 0.011 15.7 4.3 1.1 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus HALZ PF02183.18 AJW71020.1 - 0.011 15.9 2.4 0.016 15.4 2.4 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper BMFP PF04380.13 AJW71020.1 - 0.018 15.5 1.9 0.018 15.5 1.9 1.1 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_2 PF07716.15 AJW71020.1 - 0.018 15.1 5.6 0.018 15.1 2.1 1.9 1 1 1 2 2 2 0 Basic region leucine zipper BRI3BP PF14965.6 AJW71020.1 - 0.026 14.0 2.0 0.026 14.0 2.0 1.0 1 0 0 1 1 1 0 Negative regulator of p53/TP53 TolA_bind_tri PF16331.5 AJW71020.1 - 0.029 14.4 2.7 0.03 14.4 2.7 1.1 1 0 0 1 1 1 0 TolA binding protein trimerisation DivIC PF04977.15 AJW71020.1 - 0.034 13.9 5.0 0.038 13.8 5.0 1.1 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 AJW71020.1 - 0.036 14.2 5.0 0.036 14.2 5.0 1.1 1 0 0 1 1 1 0 bZIP transcription factor BLOC1_2 PF10046.9 AJW71020.1 - 0.039 14.2 2.7 0.042 14.1 2.7 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC92 PF14916.6 AJW71020.1 - 0.042 13.6 3.3 0.097 12.4 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Shugoshin_N PF07558.11 AJW71020.1 - 0.05 13.5 4.3 0.18 11.7 0.6 2.2 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 AJW71020.1 - 0.065 13.9 2.4 0.14 12.8 2.4 1.6 1 1 0 1 1 1 0 SlyX PspB PF06667.12 AJW71020.1 - 0.081 13.0 1.5 0.11 12.6 1.5 1.2 1 0 0 1 1 1 0 Phage shock protein B XhlA PF10779.9 AJW71020.1 - 0.084 13.1 5.9 0.085 13.1 5.9 1.0 1 0 0 1 1 1 0 Haemolysin XhlA DUF2968 PF11180.8 AJW71020.1 - 0.088 12.4 1.6 0.089 12.4 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Ead_Ea22 PF13935.6 AJW71020.1 - 0.17 12.6 2.7 0.17 12.6 2.7 1.0 1 0 0 1 1 1 0 Ead/Ea22-like protein LapA_dom PF06305.11 AJW71020.1 - 7 6.6 5.5 17 5.3 5.2 1.7 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain FAIM1 PF06905.13 AJW71022.1 - 0.032 14.0 0.0 0.033 13.9 0.0 1.0 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) 3D PF06725.11 AJW71023.1 - 1e-09 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 3D domain Omega-toxin PF06357.11 AJW71024.1 - 0.0039 16.9 0.4 0.0059 16.4 0.4 1.2 1 0 0 1 1 1 1 Omega-atracotoxin DUF3841 PF12952.7 AJW71024.1 - 0.095 12.5 0.1 0.1 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) DNA_primase_lrg PF04104.14 AJW71025.1 - 5.8e-05 22.6 0.5 7.2e-05 22.3 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit TetR_C_37 PF18665.1 AJW71025.1 - 0.048 14.3 4.2 0.067 13.8 0.2 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain S1-P1_nuclease PF02265.16 AJW71025.1 - 0.13 12.1 1.2 0.17 11.7 1.2 1.1 1 0 0 1 1 1 0 S1/P1 Nuclease ABC2_membrane_3 PF12698.7 AJW71025.1 - 0.24 10.5 1.4 0.78 8.8 1.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein CPDase PF07823.11 AJW71026.1 - 8.3e-10 38.7 3.1 9.5e-09 35.2 3.1 2.2 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 AJW71026.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Met_gamma_lyase PF06838.11 AJW71026.1 - 0.02 13.4 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase ID PF18543.1 AJW71027.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Intracellular delivery domain Abi_2 PF07751.11 AJW71027.1 - 0.14 12.4 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Abi-like protein SnoaL_2 PF12680.7 AJW71028.1 - 1.2e-12 48.4 0.0 1.4e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AJW71028.1 - 1.2e-06 28.9 0.0 1.5e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 AJW71028.1 - 1.5e-06 28.0 0.3 4.2e-06 26.6 0.3 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase LEH PF07858.12 AJW71028.1 - 0.0041 17.2 0.1 0.02 15.0 0.1 1.9 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Cas_Cas1 PF01867.16 AJW71030.1 - 1.1e-43 149.4 0.1 3.2e-39 134.8 0.1 2.1 1 1 0 1 1 1 1 CRISPR associated protein Cas1 DUF1664 PF07889.12 AJW71032.1 - 0.052 13.6 2.6 0.078 13.0 1.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CAP_N PF01213.19 AJW71032.1 - 0.1 12.1 2.5 0.17 11.4 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_32 PF13679.6 AJW71032.1 - 3.9 7.4 5.2 18 5.2 1.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain DUF525 PF04379.14 AJW71033.1 - 0.065 13.5 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 ApaG domain RepA_N PF06970.11 AJW71034.1 - 0.082 12.8 0.3 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus HxlR PF01638.17 AJW71036.1 - 0.057 13.3 0.1 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 HxlR-like helix-turn-helix DUF5083 PF16890.5 AJW71036.1 - 0.073 12.8 1.3 0.13 12.0 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5083) DUF4923 PF16270.5 AJW71039.1 - 0.032 14.1 0.6 0.038 13.8 0.6 1.2 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) CdiI PF07262.11 AJW71039.1 - 0.035 13.9 5.9 0.041 13.7 5.9 1.0 1 0 0 1 1 1 0 CDI immunity protein BAR_3 PF16746.5 AJW71039.1 - 0.038 13.7 4.1 0.04 13.6 4.1 1.0 1 0 0 1 1 1 0 BAR domain of APPL family Rox3 PF08633.10 AJW71039.1 - 0.064 13.5 2.0 0.086 13.1 2.0 1.1 1 0 0 1 1 1 0 Rox3 mediator complex subunit L-fibroin PF05849.11 AJW71039.1 - 0.089 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) FAD_SOX PF18371.1 AJW71039.1 - 0.27 11.6 1.7 0.97 9.8 0.8 2.0 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DsrD PF08679.11 AJW71039.1 - 0.37 11.1 4.8 1.5 9.1 0.2 2.4 1 1 1 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Sipho_Gp157 PF05565.11 AJW71039.1 - 0.38 10.8 8.0 0.72 9.9 7.9 1.6 1 1 0 1 1 1 0 Siphovirus Gp157 DNA_pol_B_2 PF03175.13 AJW71040.1 - 1.7e-24 86.6 9.0 3.2e-24 85.6 9.0 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Tmemb_18A PF09771.9 AJW71041.1 - 0.42 11.0 5.6 0.11 12.9 1.9 1.9 2 0 0 2 2 2 0 Transmembrane protein 188 AAA_21 PF13304.6 AJW71042.1 - 1.4e-18 67.8 11.2 6e-10 39.4 8.3 3.0 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AJW71042.1 - 8.4e-18 65.2 38.9 8.4e-18 65.2 38.9 2.8 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AJW71042.1 - 5.2e-11 42.4 0.2 3.4e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJW71042.1 - 4.6e-09 37.1 10.3 4.6e-09 37.1 10.3 3.3 2 2 1 3 3 3 1 AAA domain AAA_27 PF13514.6 AJW71042.1 - 0.0011 18.6 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain HNH PF01844.23 AJW71043.1 - 4e-11 42.9 5.5 1e-10 41.6 5.5 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 AJW71043.1 - 4.3e-07 29.8 0.4 1.9e-06 27.7 0.2 2.2 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 AJW71043.1 - 0.0017 18.1 1.7 0.0034 17.2 1.7 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 AJW71043.1 - 0.0048 17.0 2.3 0.045 13.9 2.3 2.4 1 1 0 1 1 1 1 HNH endonuclease ING PF12998.7 AJW71043.1 - 0.15 12.6 2.6 0.35 11.5 1.5 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Auto_anti-p27 PF06677.12 AJW71043.1 - 0.17 12.1 0.3 0.8 9.9 0.0 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NERD PF08378.11 AJW71045.1 - 7.5e-12 45.7 1.1 1.4e-11 44.8 0.0 2.0 2 1 0 2 2 2 1 Nuclease-related domain Imm74 PF15603.6 AJW71045.1 - 0.00088 19.4 2.1 0.0029 17.8 0.2 2.7 2 1 2 4 4 4 1 Immunity protein 74 HTH_45 PF14947.6 AJW71046.1 - 0.035 14.1 0.5 0.035 14.1 0.5 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix B-block_TFIIIC PF04182.12 AJW71046.1 - 0.087 13.0 0.8 0.37 11.0 0.2 2.2 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Thioredoxin_3 PF13192.6 AJW71047.1 - 0.07 13.2 0.6 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain DiS_P_DiS PF06750.13 AJW71047.1 - 0.089 12.9 1.8 8.5 6.6 0.2 2.4 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PyrI_C PF02748.15 AJW71047.1 - 0.093 12.7 0.4 0.093 12.7 0.4 2.7 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-FCS PF06467.14 AJW71047.1 - 0.11 12.4 3.8 2.2 8.3 0.2 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF2024 PF09630.10 AJW71047.1 - 0.12 12.3 0.9 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf-3CxxC_2 PF17180.4 AJW71047.1 - 0.27 12.0 5.9 1.8 9.4 1.4 2.5 1 1 1 2 2 2 0 Zinc-binding domain Sgf11 PF08209.11 AJW71047.1 - 0.28 10.8 10.4 1.3 8.6 0.4 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 AJW71047.1 - 0.4 10.3 0.2 0.4 10.3 0.2 2.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DnaJ_CXXCXGXG PF00684.19 AJW71047.1 - 0.45 10.9 6.2 6.2 7.3 2.7 3.1 2 1 0 2 2 2 0 DnaJ central domain zinc_ribbon_15 PF17032.5 AJW71047.1 - 0.83 10.5 7.2 4.7 8.0 0.2 2.5 1 1 1 2 2 2 0 zinc-ribbon family Pentapeptide_3 PF13576.6 AJW71048.1 - 1.7e-11 44.1 20.1 9.7e-05 22.5 7.6 4.7 3 1 1 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 AJW71048.1 - 8.1e-05 22.2 4.9 0.14 11.9 0.4 5.3 4 2 0 4 4 4 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AJW71048.1 - 0.0041 17.3 14.1 0.2 11.8 2.1 3.8 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) DUF3267 PF11667.8 AJW71048.1 - 0.17 12.2 1.1 8.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Putative zincin peptidase Phage_integrase PF00589.22 AJW71049.1 - 3.1e-14 53.2 1.5 3.4e-14 53.0 0.1 1.7 2 0 0 2 2 2 1 Phage integrase family DZR PF12773.7 AJW71049.1 - 0.019 15.0 0.8 0.043 13.8 0.4 1.7 2 0 0 2 2 2 0 Double zinc ribbon HscB_4_cys PF18256.1 AJW71049.1 - 0.2 11.5 0.6 0.5 10.2 0.6 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif AMNp_N PF10423.9 AJW71052.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus DUF1722 PF08349.11 AJW71052.1 - 0.069 13.4 1.5 0.19 12.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) HEPN_Apea PF18739.1 AJW71052.1 - 7.4 7.1 9.0 10 6.6 7.2 2.2 1 1 0 1 1 1 0 Apea-like HEPN ALIX_LYPXL_bnd PF13949.6 AJW71053.1 - 0.017 14.4 3.7 0.023 14.0 3.7 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF2140 PF09911.9 AJW71053.1 - 0.032 13.8 0.9 0.068 12.7 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) OMS28_porin PF03532.13 AJW71053.1 - 0.048 12.9 0.6 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 OMS28 porin BenE PF03594.13 AJW71053.1 - 0.2 10.4 1.7 0.29 9.9 1.7 1.1 1 0 0 1 1 1 0 Benzoate membrane transport protein 4HB_MCP_1 PF12729.7 AJW71053.1 - 0.3 10.6 7.7 3.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Helicase_IV_N PF12462.8 AJW71053.1 - 2.9 7.8 5.9 2.3 8.2 2.6 2.0 1 1 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF3464 PF11947.8 AJW71053.1 - 5.3 6.8 6.1 1.4 8.7 0.5 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DNA_pol_B_2 PF03175.13 AJW71054.1 - 5e-23 81.7 10.4 1.2e-22 80.5 10.4 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Condensin2nSMC PF12422.8 AJW71054.1 - 0.0089 16.2 0.2 0.26 11.5 0.0 2.3 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit GspL_C PF12693.7 AJW71055.1 - 0.00094 19.0 0.7 0.0011 18.8 0.7 1.1 1 0 0 1 1 1 1 GspL periplasmic domain Helicase_IV_N PF12462.8 AJW71055.1 - 0.13 12.2 2.8 0.17 11.8 2.5 1.3 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Vps39_2 PF10367.9 AJW71055.1 - 0.14 12.6 4.3 1 9.8 1.9 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 RecG_N PF17190.4 AJW71055.1 - 0.22 12.3 6.0 0.33 11.7 6.0 1.5 1 1 0 1 1 1 0 RecG N-terminal helical domain DUF3919 PF13057.6 AJW71055.1 - 1.6 8.3 8.3 2.1 7.9 7.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3919) FapA PF03961.13 AJW71055.1 - 2.7 6.5 7.5 3 6.3 7.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TFA2_Winged_2 PF18121.1 AJW71057.1 - 0.04 13.6 0.4 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 RBDV_coat PF06593.11 AJW71057.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein Mrr_N PF14338.6 AJW71058.1 - 2.3e-21 75.7 1.2 3.9e-21 75.0 0.5 1.8 2 0 0 2 2 2 1 Mrr N-terminal domain HTH_45 PF14947.6 AJW71058.1 - 0.19 11.8 3.4 0.5 10.4 0.3 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix N6_N4_Mtase PF01555.18 AJW71059.1 - 1.4e-28 100.2 0.2 9.8e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Cons_hypoth95 PF03602.15 AJW71059.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 AJW71059.1 - 0.0015 18.4 0.0 0.0039 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TilS_C PF11734.8 AJW71059.1 - 0.062 12.7 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 TilS substrate C-terminal domain Methyltransf_11 PF08241.12 AJW71059.1 - 0.091 13.4 0.0 16 6.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 AJW71059.1 - 0.1 13.3 0.0 0.67 10.7 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Csa1 PF06023.12 AJW71060.1 - 5.2e-09 35.9 0.0 5.6e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 Csa1 PF06023.12 AJW71061.1 - 9.1e-29 100.7 0.0 1.1e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 PDDEXK_1 PF12705.7 AJW71061.1 - 0.00092 19.2 0.9 0.0013 18.8 0.9 1.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Tnp_P_element PF12017.8 AJW71061.1 - 0.019 14.4 0.6 0.044 13.2 0.3 1.7 2 0 0 2 2 2 0 Transposase protein DUF1091 PF06477.13 AJW71061.1 - 0.024 15.1 1.0 0.23 12.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) DUF4505 PF14956.6 AJW71061.1 - 0.026 14.3 0.3 0.098 12.4 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4505) AJAP1_PANP_C PF15298.6 AJW71061.1 - 0.08 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3135 PF11333.8 AJW71062.1 - 0.045 14.0 1.2 6.5 7.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) HTH_22 PF13309.6 AJW71062.1 - 0.098 12.7 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 HTH domain DUF2791 PF10923.8 AJW71063.1 - 2.1e-06 26.9 0.6 0.011 14.6 0.2 2.2 2 0 0 2 2 2 2 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.6 AJW71063.1 - 2.8e-06 27.7 0.2 0.00012 22.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AJW71063.1 - 3e-05 24.5 0.0 5.5e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AJW71063.1 - 3.8e-05 23.7 0.9 5.9e-05 23.1 0.9 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 AJW71063.1 - 0.0042 16.4 0.4 0.015 14.5 0.1 1.8 2 0 0 2 2 2 1 KAP family P-loop domain Kinesin PF00225.23 AJW71063.1 - 0.01 14.8 0.0 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Kinesin motor domain ResIII PF04851.15 AJW71063.1 - 0.012 15.6 0.1 0.027 14.5 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 AJW71063.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein YppF PF14178.6 AJW71063.1 - 2.6 8.0 4.3 19 5.2 0.0 2.7 2 1 1 3 3 3 0 YppF-like protein Cas_Cas1 PF01867.16 AJW71065.1 - 2.3e-48 164.8 0.3 2.9e-48 164.4 0.3 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 AnfG_VnfG PF03139.15 AJW71065.1 - 0.022 14.8 0.3 0.072 13.2 0.3 1.8 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit V-ATPase_G PF03179.15 AJW71066.1 - 0.025 15.1 0.3 0.028 14.9 0.3 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit GTP_EFTU PF00009.27 AJW71067.1 - 6.5e-61 205.3 0.7 1.1e-60 204.5 0.7 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AJW71067.1 - 3.6e-22 78.2 0.0 1.3e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 AJW71067.1 - 1.4e-20 73.2 0.2 6.7e-20 71.0 0.4 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 AJW71067.1 - 1.9e-20 72.9 0.0 1.4e-19 70.0 0.0 2.3 1 1 1 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 AJW71067.1 - 4e-12 46.4 0.1 1.4e-11 44.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AJW71067.1 - 0.0033 17.5 0.1 0.008 16.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 AJW71067.1 - 0.034 13.9 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 AJW71067.1 - 0.052 13.0 0.0 0.19 11.1 0.0 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit CortBP2 PF09727.9 AJW71067.1 - 0.067 13.1 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 SIS PF01380.22 AJW71068.1 - 1.5e-09 37.8 2.2 3.7e-05 23.6 0.0 2.9 2 1 0 2 2 2 2 SIS domain TMEM51 PF15345.6 AJW71070.1 - 0.00043 20.2 0.1 0.00049 20.0 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 Gram_pos_anchor PF00746.21 AJW71070.1 - 0.001 19.0 8.5 0.012 15.5 0.0 2.7 3 0 0 3 3 3 2 LPXTG cell wall anchor motif Tetraspanin PF00335.20 AJW71070.1 - 0.0013 18.5 0.4 0.0016 18.2 0.4 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF3098 PF11297.8 AJW71070.1 - 0.013 15.1 1.0 0.33 10.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) MFS_2 PF13347.6 AJW71070.1 - 0.019 13.5 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein SfLAP PF11139.8 AJW71070.1 - 0.021 14.2 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Neurensin PF14927.6 AJW71070.1 - 0.078 12.7 0.1 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 Neurensin Thiamine_BP PF01910.17 AJW71073.1 - 1.1e-24 86.2 2.1 1.2e-24 86.0 2.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Radical_SAM PF04055.21 AJW71074.1 - 6.4e-16 59.2 0.0 1.3e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AJW71074.1 - 0.01 16.0 0.1 0.038 14.1 0.0 1.9 1 1 1 2 2 2 0 4Fe-4S single cluster domain TPR_1 PF00515.28 AJW71075.1 - 1.1e-26 91.5 12.1 4.1e-07 29.5 1.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJW71075.1 - 2.7e-23 80.1 8.2 4.4e-05 23.3 0.2 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 AJW71075.1 - 6.8e-21 73.7 7.0 2.7e-06 27.0 0.1 4.2 1 1 3 4 4 4 4 TPR repeat TPR_12 PF13424.6 AJW71075.1 - 5.4e-16 58.7 14.5 5.2e-06 26.6 0.9 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJW71075.1 - 1.5e-14 52.9 9.4 0.00027 20.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 AJW71075.1 - 4.4e-14 51.4 1.5 0.003 17.5 0.1 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 AJW71075.1 - 8.1e-14 51.1 1.7 0.015 16.1 0.0 4.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 AJW71075.1 - 1.8e-12 47.5 10.0 6.9e-07 29.7 0.4 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AJW71075.1 - 2.2e-12 47.4 0.4 4.6e-05 24.0 0.1 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 AJW71075.1 - 5e-12 45.3 5.8 0.00023 21.3 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 AJW71075.1 - 7.5e-11 42.0 0.0 4.7e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 AJW71075.1 - 7.3e-10 38.4 0.4 0.018 14.9 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_3 PF07720.12 AJW71075.1 - 3e-08 33.5 7.7 0.097 12.7 0.4 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat MIT PF04212.18 AJW71075.1 - 1.1e-07 31.8 5.9 0.52 10.4 0.1 4.3 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 AJW71075.1 - 3.8e-06 27.0 0.1 1.2 9.2 0.0 3.5 1 1 2 3 3 3 2 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 AJW71075.1 - 6.7e-06 26.2 3.4 0.00012 22.2 0.4 2.2 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AJW71075.1 - 1.7e-05 25.1 10.3 4.7 8.1 0.3 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat NARP1 PF12569.8 AJW71075.1 - 9.5e-05 21.5 1.9 0.026 13.4 0.1 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 AJW71075.1 - 0.00023 21.1 4.6 0.91 9.6 0.1 4.3 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 AJW71075.1 - 0.0038 16.7 0.2 0.84 8.9 0.0 2.4 2 1 1 3 3 3 1 MalT-like TPR region TOM20_plant PF06552.12 AJW71075.1 - 0.054 13.2 1.5 7.3 6.3 0.2 2.8 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 PSD5 PF07637.11 AJW71075.1 - 0.07 13.5 0.0 0.46 10.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1595) PPR PF01535.20 AJW71075.1 - 0.07 13.4 1.7 4.9 7.6 0.1 3.6 5 0 0 5 5 2 0 PPR repeat 4HB_MCP_1 PF12729.7 AJW71075.1 - 0.072 12.6 0.3 0.072 12.6 0.3 2.1 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction MatP PF06303.12 AJW71075.1 - 0.08 13.5 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 1 0 MatP N-terminal domain EIF_2_alpha PF07541.12 AJW71075.1 - 0.15 12.2 1.6 1.1 9.4 1.6 2.2 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Alkyl_sulf_dimr PF14863.6 AJW71075.1 - 0.25 11.8 1.3 1.2 9.5 0.1 2.1 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation PPR_2 PF13041.6 AJW71075.1 - 0.35 11.1 1.3 1e+02 3.2 0.1 3.9 4 0 0 4 4 4 0 PPR repeat family SHNi-TPR PF10516.9 AJW71075.1 - 0.54 9.7 5.3 17 4.9 0.1 4.0 4 1 0 4 4 4 0 SHNi-TPR TPR_1 PF00515.28 AJW71076.1 - 2.5e-19 68.2 0.1 8.9e-10 38.0 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AJW71076.1 - 7e-18 63.2 0.0 1.6e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AJW71076.1 - 4e-13 48.4 0.0 1.7e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 AJW71076.1 - 2.2e-12 46.4 0.0 6.9e-06 25.6 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.6 AJW71076.1 - 5.3e-10 38.6 0.0 0.00042 20.1 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 AJW71076.1 - 2.8e-09 36.7 1.2 1.2e-05 25.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AJW71076.1 - 3.9e-09 37.0 0.0 4.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 AJW71076.1 - 7.3e-09 35.7 0.0 8.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AJW71076.1 - 1.6e-08 34.7 0.0 0.00062 20.4 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AJW71076.1 - 8.3e-08 32.4 0.0 3.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJW71076.1 - 1.1e-07 32.2 0.0 1.3e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 AJW71076.1 - 0.00013 21.7 0.0 0.63 10.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat NRBF2_MIT PF17169.4 AJW71076.1 - 0.00086 19.5 0.0 0.24 11.7 0.0 2.1 1 1 1 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 ANAPC3 PF12895.7 AJW71076.1 - 0.0011 19.1 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 AJW71076.1 - 0.002 18.2 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 AJW71076.1 - 0.0074 16.9 0.0 6.4 7.6 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 AJW71076.1 - 0.0083 16.6 0.0 0.078 13.4 0.0 1.9 1 1 0 2 2 2 1 Bacterial transcriptional activator domain DUF3856 PF12968.7 AJW71076.1 - 0.015 15.4 0.0 0.12 12.5 0.0 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 AJW71076.1 - 0.017 15.4 0.7 4.7 7.7 0.1 2.5 2 1 0 2 2 2 0 PPR repeat MAS20 PF02064.15 AJW71076.1 - 0.017 15.2 0.0 0.15 12.1 0.0 1.9 1 1 1 2 2 2 0 MAS20 protein import receptor Fis1_TPR_C PF14853.6 AJW71076.1 - 0.027 14.5 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AJW71076.1 - 0.049 14.1 0.0 0.053 14.0 0.0 1.0 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation SRP_TPR_like PF17004.5 AJW71076.1 - 0.18 11.8 0.0 0.96 9.5 0.0 1.8 1 1 1 2 2 2 0 Putative TPR-like repeat HTH_AsnC-type PF13404.6 AJW71077.1 - 6e-12 45.2 1.2 9.7e-12 44.5 1.2 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJW71077.1 - 4.3e-11 42.2 3.3 6.3e-11 41.7 1.3 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 AJW71077.1 - 1.9e-10 40.5 0.2 3.2e-10 39.8 0.2 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 AJW71077.1 - 0.00025 20.9 1.3 0.00044 20.1 1.0 1.6 1 1 0 1 1 1 1 HTH domain HTH_50 PF18024.1 AJW71077.1 - 0.00065 19.3 0.1 0.0032 17.0 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AJW71077.1 - 0.0058 16.6 0.2 0.011 15.7 0.2 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 AJW71077.1 - 0.025 14.7 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DDRGK PF09756.9 AJW71077.1 - 0.026 14.1 0.8 0.069 12.7 0.1 1.8 1 1 1 2 2 2 0 DDRGK domain HTH_27 PF13463.6 AJW71077.1 - 0.042 14.4 0.3 0.67 10.5 0.1 2.6 2 1 1 3 3 3 0 Winged helix DNA-binding domain HxlR PF01638.17 AJW71077.1 - 0.043 13.7 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix MarR PF01047.22 AJW71077.1 - 0.077 12.9 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 AJW71077.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 MarR family DnaJ PF00226.31 AJW71078.1 - 2.5e-21 75.5 2.3 2.5e-21 75.5 2.3 1.9 2 1 0 2 2 2 1 DnaJ domain ArsP_2 PF11449.8 AJW71078.1 - 0.055 12.7 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter O-ag_pol_Wzy PF14296.6 AJW71078.1 - 0.06 12.0 0.2 0.076 11.7 0.2 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy YMF19 PF02326.15 AJW71078.1 - 0.26 12.1 1.3 11 6.9 0.1 2.4 1 1 0 2 2 2 0 Plant ATP synthase F0 PDEase_I PF00233.19 AJW71080.1 - 0.0053 16.5 0.1 0.0053 16.5 0.1 1.8 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 AJW71080.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 HD domain FAD-oxidase_C PF02913.19 AJW71081.1 - 7.1e-43 147.0 0.0 8.9e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AJW71081.1 - 4.8e-30 104.1 0.0 1e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Cytokin-bind PF09265.10 AJW71081.1 - 0.0049 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding ASH PF15780.5 AJW71082.1 - 0.024 14.8 0.1 0.035 14.3 0.1 1.2 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1425 PF07233.12 AJW71082.1 - 0.073 13.0 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) Transglut_C PF00927.22 AJW71082.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain XPA_N PF01286.18 AJW71085.1 - 0.018 15.1 4.5 0.17 12.0 0.1 2.0 1 1 1 2 2 2 0 XPA protein N-terminal CBM_14 PF01607.24 AJW71086.1 - 7.1e-06 26.1 1.0 0.13 12.4 0.1 2.4 1 1 1 2 2 2 2 Chitin binding Peritrophin-A domain zinc_ribbon_2 PF13240.6 AJW71086.1 - 3.1e-05 23.5 1.2 3.1e-05 23.5 1.2 2.0 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.7 AJW71086.1 - 0.00016 21.6 0.3 0.00037 20.5 0.3 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AJW71086.1 - 0.00064 19.0 1.2 0.00064 19.0 1.2 2.4 4 0 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AJW71086.1 - 0.0033 18.1 0.7 0.0065 17.2 0.7 1.5 1 0 0 1 1 1 1 zinc-ribbon family COX16 PF14138.6 AJW71086.1 - 0.023 15.2 0.1 0.091 13.3 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Pacifastin_I PF05375.13 AJW71086.1 - 0.03 14.0 1.0 7.7 6.3 0.1 2.4 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) AcrZ PF10766.9 AJW71086.1 - 0.086 12.4 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ DUF1980 PF09323.10 AJW71086.1 - 0.38 10.6 1.6 0.41 10.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Response_reg PF00072.24 AJW71087.1 - 4.4e-18 65.5 0.2 5.9e-18 65.1 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain 2-Hacid_dh_C PF02826.19 AJW71087.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Response_reg PF00072.24 AJW71089.1 - 8.5e-16 58.1 0.1 9.7e-16 57.9 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AJW71089.1 - 0.058 13.4 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain AFOR_C PF01314.18 AJW71089.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 DUF1176 PF06674.11 AJW71092.1 - 0.031 13.7 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Sod_Fe_C PF02777.18 AJW71093.1 - 3.9e-39 132.9 2.3 7e-39 132.1 2.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AJW71093.1 - 2.5e-23 82.4 1.1 2.8e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HTH_5 PF01022.20 AJW71094.1 - 0.00087 19.1 0.4 0.0046 16.8 0.2 2.3 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family PadR PF03551.14 AJW71094.1 - 0.005 16.8 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AJW71094.1 - 0.0091 16.0 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain DUF2513 PF10711.9 AJW71094.1 - 0.056 13.7 0.5 0.17 12.2 0.1 2.0 2 1 1 3 3 3 0 Hypothetical protein (DUF2513) HTH_34 PF13601.6 AJW71094.1 - 0.094 12.9 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain cwf21 PF08312.12 AJW71094.1 - 0.43 10.8 4.8 11 6.3 0.0 2.7 2 1 0 2 2 2 0 cwf21 domain SNF2_N PF00176.23 AJW71095.1 - 8.3e-38 130.0 0.1 1.2e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AJW71095.1 - 4.2e-11 43.2 4.3 5.2e-11 42.9 0.0 3.1 4 1 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 AJW71095.1 - 4.6e-08 33.3 2.2 8.4e-08 32.4 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AJW71095.1 - 4e-05 23.5 0.1 0.00014 21.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Hist_deacetyl PF00850.19 AJW71095.1 - 0.77 9.2 2.5 1.6 8.1 2.3 1.6 1 1 0 1 1 1 0 Histone deacetylase domain CarboxypepD_reg PF13620.6 AJW71097.1 - 0.00035 20.8 0.1 0.00061 20.0 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain UVR PF02151.19 AJW71097.1 - 0.034 13.9 0.2 0.034 13.9 0.2 2.5 3 0 0 3 3 3 0 UvrB/uvrC motif Dioxygenase_C PF00775.21 AJW71097.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Dioxygenase Big_1 PF02369.16 AJW71097.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) ArsC PF03960.15 AJW71098.1 - 1.1e-12 47.7 0.2 3.4e-12 46.2 0.2 1.7 1 1 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AJW71098.1 - 0.0013 18.9 0.2 0.0081 16.4 0.1 1.9 2 0 0 2 2 2 1 Glutaredoxin SapB_1 PF05184.15 AJW71098.1 - 0.054 13.5 0.6 2.1 8.5 0.1 2.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 PriCT_1 PF08708.11 AJW71098.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Orthopox_A36R PF05950.11 AJW71100.1 - 0.12 12.5 3.5 2.2 8.4 0.3 2.1 1 1 1 2 2 2 0 Orthopoxvirus A36R protein DUF2196 PF09962.9 AJW71101.1 - 6e-29 99.8 1.5 6.4e-29 99.7 1.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Zn_ribbon_SprT PF17283.2 AJW71102.1 - 7.2e-05 22.6 7.4 0.018 15.0 0.8 2.3 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Molybdop_Fe4S4 PF04879.16 AJW71102.1 - 0.015 15.3 7.7 0.43 10.6 0.8 2.2 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain zf-UBR PF02207.20 AJW71102.1 - 0.031 14.4 9.2 1.1 9.5 1.1 2.4 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DNA_RNApol_7kD PF03604.13 AJW71102.1 - 0.034 13.8 17.9 0.43 10.3 4.5 2.7 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF1059 PF06348.11 AJW71102.1 - 0.15 12.3 5.4 2.1 8.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zinc_ribbon_6 PF14599.6 AJW71102.1 - 0.2 11.7 12.5 0.53 10.3 2.0 2.9 2 2 2 4 4 4 0 Zinc-ribbon SCIFF PF13165.6 AJW71102.1 - 1.4 8.9 10.1 5.1 7.1 0.3 3.4 4 0 0 4 4 4 0 Six-cysteine peptide SCIFF Elf1 PF05129.13 AJW71102.1 - 2.5 8.2 10.6 2.1 8.4 0.1 3.1 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like LIM PF00412.22 AJW71102.1 - 3.2 8.1 14.1 4.9 7.5 2.9 2.3 2 0 0 2 2 2 0 LIM domain ZZ PF00569.17 AJW71102.1 - 5 7.0 18.1 5.3 6.9 0.3 4.0 4 0 0 4 4 4 0 Zinc finger, ZZ type BPD_transp_1 PF00528.22 AJW71103.1 - 2e-35 122.2 22.0 2e-35 122.2 22.0 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF5400 PF17379.2 AJW71103.1 - 0.0012 19.3 0.2 0.0012 19.3 0.2 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF5400) DUF3481 PF11980.8 AJW71103.1 - 0.32 10.7 2.2 11 5.7 0.1 2.7 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein BPD_transp_1 PF00528.22 AJW71104.1 - 3.2e-25 89.0 9.7 3.2e-25 89.0 9.7 2.3 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AJW71104.1 - 0.0086 16.0 0.0 0.0086 16.0 0.0 2.6 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C Kelch_6 PF13964.6 AJW71104.1 - 0.079 13.3 0.3 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Kelch motif zf-NADH-PPase PF09297.11 AJW71106.1 - 0.018 14.7 3.3 0.065 12.9 0.7 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Peptidase_C74 PF12387.8 AJW71106.1 - 0.044 13.3 1.6 0.06 12.8 1.6 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Zn_ribbon_recom PF13408.6 AJW71106.1 - 0.25 11.9 4.9 1.9 9.1 4.9 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 AJW71106.1 - 0.3 10.7 1.1 0.76 9.4 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 AJW71106.1 - 0.87 9.8 3.9 3.6 7.8 3.9 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Prok-JAB PF14464.6 AJW71107.1 - 9.4e-12 44.8 0.0 1.6e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain RadC PF04002.15 AJW71107.1 - 0.022 14.7 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 RadC-like JAB domain Spc7 PF08317.11 AJW71108.1 - 0.003 16.5 31.1 0.011 14.7 3.9 2.9 2 1 1 3 3 3 2 Spc7 kinetochore protein APG6_N PF17675.1 AJW71108.1 - 0.0095 16.5 31.1 0.084 13.4 3.5 2.9 3 0 0 3 3 2 2 Apg6 coiled-coil region Laminin_II PF06009.12 AJW71108.1 - 0.024 14.6 1.7 0.024 14.6 1.7 4.8 2 1 3 5 5 5 0 Laminin Domain II Occludin_ELL PF07303.13 AJW71108.1 - 0.14 12.9 24.2 0.32 11.7 6.7 4.4 2 2 2 4 4 4 0 Occludin homology domain CENP-Q PF13094.6 AJW71108.1 - 0.17 12.1 29.6 0.32 11.2 9.8 3.8 3 1 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3450 PF11932.8 AJW71108.1 - 0.2 10.9 24.4 0.53 9.5 2.2 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Tnp_22_trimer PF17489.2 AJW71108.1 - 0.22 11.5 0.1 0.22 11.5 0.1 3.8 3 1 0 3 3 3 0 L1 transposable element trimerization domain Rx_N PF18052.1 AJW71108.1 - 0.25 11.7 11.9 1.8 8.9 0.5 4.1 3 1 1 4 4 4 0 Rx N-terminal domain FapA PF03961.13 AJW71108.1 - 0.34 9.5 32.5 0.7 8.4 3.7 2.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A Syntaxin PF00804.25 AJW71108.1 - 0.82 9.3 25.1 0.22 11.2 1.2 3.5 2 1 1 3 3 3 0 Syntaxin DUF4972 PF16342.5 AJW71108.1 - 1.3 8.7 16.7 1.3 8.7 7.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) Seryl_tRNA_N PF02403.22 AJW71108.1 - 1.3 9.2 33.9 1.6 9.0 15.6 4.2 2 2 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Nsp1_C PF05064.13 AJW71108.1 - 1.4 8.8 23.9 1.2 8.9 1.0 4.6 3 1 1 4 4 4 0 Nsp1-like C-terminal region T3SSipB PF16535.5 AJW71108.1 - 1.7 9.1 17.7 2.6 8.5 7.2 3.5 1 1 1 3 3 3 0 Type III cell invasion protein SipB DUF745 PF05335.13 AJW71108.1 - 2.2 8.0 11.7 3.8 7.2 5.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Sec34 PF04136.15 AJW71108.1 - 2.4 8.0 31.5 5.1 7.0 0.6 4.5 2 1 3 6 6 5 0 Sec34-like family MCPsignal PF00015.21 AJW71108.1 - 2.4 7.9 21.9 1.1 9.0 0.2 4.1 3 1 1 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_13 PF13166.6 AJW71108.1 - 3.2 6.3 38.2 0.31 9.6 13.6 2.1 1 1 1 2 2 2 0 AAA domain Tropomyosin_1 PF12718.7 AJW71108.1 - 3.4 7.8 25.5 0.63 10.2 12.2 3.1 2 1 0 2 2 2 0 Tropomyosin like Syntaxin-6_N PF09177.11 AJW71108.1 - 4 8.1 24.0 18 5.9 1.2 4.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal T3SS_basalb_I PF17001.5 AJW71108.1 - 4.6 7.9 8.6 40 4.9 2.0 3.9 1 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI CHD5 PF04420.14 AJW71108.1 - 4.7 7.1 11.5 7 6.5 9.6 2.3 1 1 1 2 2 2 0 CHD5-like protein Mod_r PF07200.13 AJW71108.1 - 5 7.2 34.8 0.51 10.4 15.2 3.5 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 AJW71108.1 - 7 7.0 19.5 7.9 6.8 0.1 6.0 3 2 1 4 4 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 AJW71108.1 - 9.7 6.7 33.2 0.94 10.0 0.4 6.1 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein RPW8 PF05659.11 AJW71108.1 - 9.7 5.9 26.3 0.99 9.1 1.8 4.1 2 2 2 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Polyketide_cyc2 PF10604.9 AJW71109.1 - 3.3e-14 53.4 0.0 3.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJW71109.1 - 0.0038 17.4 0.0 0.0045 17.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AsnC_trans_reg PF01037.21 AJW71114.1 - 6.7e-10 38.8 0.2 7.9e-10 38.6 0.2 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain LAGLIDADG_WhiA PF14527.6 AJW71114.1 - 0.068 13.3 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Nitroreductase PF00881.24 AJW71115.1 - 4.2e-26 92.0 0.1 7.3e-13 48.9 0.0 2.2 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 AJW71115.1 - 2.6e-10 40.3 0.2 0.00016 21.4 0.0 2.9 2 1 0 2 2 2 2 Putative TM nitroreductase Phytochelatin PF05023.14 AJW71118.1 - 0.011 14.9 1.3 0.019 14.2 0.3 1.9 2 0 0 2 2 2 0 Phytochelatin synthase HARE-HTH PF05066.13 AJW71119.1 - 0.16 12.4 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain SAC3 PF12209.8 AJW71120.1 - 0.0019 18.3 0.3 0.025 14.8 0.1 2.1 1 1 1 2 2 2 1 Leucine permease transcriptional regulator helical domain Cauli_AT PF03233.13 AJW71120.1 - 0.024 14.6 1.2 0.026 14.4 1.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein EF-hand_11 PF08976.11 AJW71120.1 - 0.1 13.5 0.2 0.14 13.0 0.2 1.2 1 0 0 1 1 1 0 EF-hand domain XPG_I PF00867.18 AJW71121.1 - 1.1e-22 80.2 0.0 2.7e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 AJW71121.1 - 2.2e-21 76.2 0.0 1e-20 74.1 0.0 2.0 1 1 1 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 AJW71121.1 - 3.8e-05 24.2 0.0 0.00013 22.5 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF4878 PF12870.7 AJW71121.1 - 0.0074 16.6 0.5 0.027 14.8 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) HHH_5 PF14520.6 AJW71121.1 - 0.059 14.0 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain PAS PF00989.25 AJW71122.1 - 1.4e-10 41.2 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AJW71122.1 - 7.4e-09 35.8 0.2 1.3e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 AJW71122.1 - 1.8e-06 28.1 0.0 2.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AJW71122.1 - 0.00059 20.1 0.0 0.00075 19.7 0.0 1.1 1 0 0 1 1 1 1 PAS fold PheRS_DBD2 PF18554.1 AJW71122.1 - 0.087 12.8 0.7 0.2 11.6 0.7 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Herpes_UL46 PF03387.14 AJW71122.1 - 0.15 10.7 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL46 protein SepF PF04472.12 AJW71122.1 - 0.16 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Cell division protein SepF AMP-binding PF00501.28 AJW71123.1 - 3.1e-95 319.3 0.0 3.8e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AJW71123.1 - 6.5e-26 91.1 1.0 9.6e-26 90.6 0.2 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AJW71123.1 - 2.7e-16 59.2 4.7 7.1e-16 57.9 4.7 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus CdvA PF18822.1 AJW71124.1 - 4.6e-33 113.7 8.5 7e-33 113.1 8.5 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain ABC_tran_CTD PF16326.5 AJW71124.1 - 0.0012 19.1 5.5 0.11 12.7 2.6 2.5 2 0 0 2 2 2 2 ABC transporter C-terminal domain CBFD_NFYB_HMF PF00808.23 AJW71124.1 - 0.01 16.1 0.6 0.023 15.0 0.6 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Baculo_PEP_C PF04513.12 AJW71124.1 - 0.017 15.1 1.5 0.043 13.9 1.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliT PF05400.13 AJW71124.1 - 0.051 14.4 3.9 2.5 9.0 2.3 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Prominin PF05478.11 AJW71124.1 - 0.081 10.9 2.2 0.1 10.5 2.2 1.1 1 0 0 1 1 1 0 Prominin Pox_A_type_inc PF04508.12 AJW71124.1 - 0.1 12.5 0.1 0.39 10.7 0.1 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA_13 PF13166.6 AJW71124.1 - 0.18 10.4 6.5 0.24 10.0 6.5 1.1 1 0 0 1 1 1 0 AAA domain PRKG1_interact PF15898.5 AJW71124.1 - 3 8.8 9.5 4.9 8.1 5.4 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 AJW71124.1 - 9.9 5.3 6.6 12 5.0 0.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein Thy1 PF02511.15 AJW71126.1 - 3e-35 121.7 1.6 3.6e-19 69.3 1.1 2.2 2 0 0 2 2 2 2 Thymidylate synthase complementing protein SelR PF01641.18 AJW71127.1 - 1.8e-54 183.0 1.1 2e-54 182.8 1.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AJW71127.1 - 0.0013 18.9 1.3 0.0031 17.7 1.3 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 AJW71127.1 - 0.015 14.2 1.6 0.32 9.8 0.1 2.0 1 1 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_L37e PF01907.19 AJW71127.1 - 0.029 14.5 2.1 0.35 11.1 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e Lar_restr_allev PF14354.6 AJW71127.1 - 0.27 11.6 3.4 4.8 7.6 3.4 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF983 PF06170.12 AJW71127.1 - 0.38 11.2 2.0 6.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Homoserine_dh PF00742.19 AJW71129.1 - 2.4e-55 187.1 0.1 3.8e-55 186.5 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase ELFV_dehydrog PF00208.21 AJW71129.1 - 6.5e-07 29.3 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_3 PF03447.16 AJW71129.1 - 2.2e-06 28.3 0.0 4.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PUA PF01472.20 AJW71130.1 - 1.9e-18 66.2 0.2 2.8e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 AJW71130.1 - 0.012 15.8 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 UPF0113 PUA domain DUF5121 PF17165.4 AJW71130.1 - 0.036 14.5 0.1 0.33 11.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5121) Mut7-C PF01927.16 AJW71131.1 - 2.2e-41 141.3 0.1 2.5e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF5615 PF18480.1 AJW71131.1 - 0.0012 18.5 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) PIN_10 PF18478.1 AJW71131.1 - 0.0048 17.1 0.3 0.024 14.9 0.3 2.0 1 1 0 1 1 1 1 PIN like domain zf-DNA_Pol PF08996.10 AJW71131.1 - 0.013 15.3 0.3 0.017 14.9 0.3 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger GcpE PF04551.14 AJW71131.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 GcpE protein zf_CopZ PF18423.1 AJW71131.1 - 0.024 14.6 0.3 0.039 13.9 0.3 1.4 1 0 0 1 1 1 0 Zinc binding domain Rad50_zn_hook PF04423.14 AJW71131.1 - 0.024 14.5 2.6 0.13 12.2 2.6 2.2 1 1 0 1 1 1 0 Rad50 zinc hook motif FemAB PF02388.16 AJW71131.1 - 0.046 12.6 0.1 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 FemAB family UPF0515 PF15135.6 AJW71131.1 - 0.059 12.7 1.1 0.068 12.5 1.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 zf-RING_7 PF02591.15 AJW71131.1 - 0.091 13.0 0.4 3.2 8.0 0.1 2.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ACC PF17848.1 AJW71131.1 - 0.29 11.2 2.6 15 5.7 0.2 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Rubredoxin_2 PF18073.1 AJW71131.1 - 0.71 9.7 5.6 1.3 8.8 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Proteasome PF00227.26 AJW71132.1 - 5.1e-46 156.6 0.0 6.2e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DoxX PF07681.12 AJW71134.1 - 1.3e-14 54.5 6.6 1.3e-14 54.5 6.6 1.6 1 1 0 1 1 1 1 DoxX DoxD PF04173.13 AJW71134.1 - 3.5e-05 23.8 4.6 5.6e-05 23.1 4.1 1.5 1 1 1 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.6 AJW71134.1 - 0.00084 19.4 5.8 0.0015 18.6 5.8 1.5 1 1 0 1 1 1 1 DoxX-like family Calici_PP_N PF08405.11 AJW71134.1 - 0.0096 14.8 1.8 0.012 14.4 1.8 1.0 1 0 0 1 1 1 1 Viral polyprotein N-terminal Peptidase_M20 PF01546.28 AJW71135.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AJW71135.1 - 6.5e-14 51.8 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Tox-PL-2 PF15643.6 AJW71135.1 - 0.017 15.2 0.1 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 Papain fold toxin 2 YARHG PF13308.6 AJW71135.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 YARHG domain Carb_kinase PF01256.17 AJW71136.1 - 1.1e-46 159.3 0.2 1.3e-46 159.1 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 AJW71136.1 - 4.9e-09 35.9 0.0 8.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 AJW71136.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Cation_ATPase PF13246.6 AJW71136.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Cation transport ATPase (P-type) GCD14 PF08704.10 AJW71137.1 - 4.6e-34 118.2 0.0 1e-33 117.1 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 AJW71137.1 - 8.5e-10 38.7 0.0 1.4e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AJW71137.1 - 5.2e-08 32.8 0.0 1.1e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW71137.1 - 2.8e-07 31.1 0.0 6.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AJW71137.1 - 1.7e-06 29.0 0.0 5.3e-06 27.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJW71137.1 - 3.1e-06 26.7 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 AJW71137.1 - 4.6e-05 24.1 0.0 0.00014 22.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJW71137.1 - 4.9e-05 23.9 0.0 0.0001 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 AJW71137.1 - 9.1e-05 21.7 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin Methyltr_RsmB-F PF01189.17 AJW71137.1 - 0.00023 20.8 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_3 PF01596.17 AJW71137.1 - 0.0003 20.0 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase GCD14_N PF14801.6 AJW71137.1 - 0.00031 20.5 0.5 0.0007 19.4 0.1 1.7 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term MTS PF05175.14 AJW71137.1 - 0.00035 20.2 0.0 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 AJW71137.1 - 0.00042 19.8 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 AJW71137.1 - 0.00042 19.5 0.0 0.00069 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 AJW71137.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 AJW71137.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 AJW71137.1 - 0.077 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CMAS PF02353.20 AJW71137.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 AJW71137.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 AJW71137.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) HNH_5 PF14279.6 AJW71138.1 - 0.0045 16.8 0.7 3 7.8 0.1 2.4 2 0 0 2 2 2 2 HNH endonuclease DZR PF12773.7 AJW71138.1 - 0.012 15.6 0.2 0.018 15.1 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-LITAF-like PF10601.9 AJW71138.1 - 0.03 14.6 1.4 4.4 7.6 0.1 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DASH_Ask1 PF08655.10 AJW71138.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Ask1 zf-HIT PF04438.16 AJW71138.1 - 0.077 12.9 1.5 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 HIT zinc finger SAP30_Sin3_bdg PF13867.6 AJW71138.1 - 0.093 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 zf_UBZ PF18439.1 AJW71138.1 - 0.1 12.2 2.7 4.4 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 AJW71138.1 - 0.21 11.6 3.2 5.5 7.0 3.3 2.1 1 1 1 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 AJW71138.1 - 0.35 11.0 3.0 5.8 7.1 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 AJW71140.1 - 0.015 15.3 0.2 0.015 15.3 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NRDD PF13597.6 AJW71140.1 - 0.032 13.0 1.2 0.036 12.9 1.2 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase PolC_DP2 PF03833.13 AJW71140.1 - 0.063 11.1 0.0 0.063 11.1 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF3025 PF11227.8 AJW71141.1 - 0.011 15.5 0.1 0.022 14.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3025) DUF1216 PF06746.11 AJW71141.1 - 0.015 15.3 2.9 0.015 15.3 2.9 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1216) DUF4777 PF16007.5 AJW71141.1 - 0.11 12.8 0.2 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Erf4 PF10256.9 AJW71141.1 - 0.16 12.0 6.9 0.05 13.7 3.7 1.8 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family TrmB PF01978.19 AJW71141.1 - 0.2 11.5 1.2 6.4 6.7 0.0 3.0 2 1 1 4 4 4 0 Sugar-specific transcriptional regulator TrmB DUF4404 PF14357.6 AJW71141.1 - 0.23 12.1 3.3 0.32 11.7 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) KicB PF03882.14 AJW71141.1 - 0.27 11.5 3.0 7.6 6.8 0.1 2.2 1 1 1 2 2 2 0 MukF winged-helix domain MRPL52 PF18699.1 AJW71141.1 - 0.7 10.1 10.1 2.7 8.3 3.8 2.7 3 0 0 3 3 3 0 Mitoribosomal protein mL52 zf-CRD PF17979.1 AJW71141.1 - 1.7 8.7 6.0 0.72 9.9 0.1 2.3 1 1 2 3 3 3 0 Cysteine rich domain with multizinc binding regions PCRF PF03462.18 AJW71141.1 - 2.3 8.0 5.9 4.3 7.2 5.9 1.4 1 0 0 1 1 1 0 PCRF domain dCache_1 PF02743.18 AJW71142.1 - 3.2e-25 89.4 4.8 5.2e-12 46.1 0.0 3.1 2 2 2 4 4 4 2 Cache domain MCPsignal PF00015.21 AJW71142.1 - 5.8e-22 78.3 5.5 8.7e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Diacid_rec PF05651.13 AJW71142.1 - 0.0001 22.0 0.1 2.9 7.6 0.1 3.9 3 0 0 3 3 3 2 Putative sugar diacid recognition zf-C4H2 PF10146.9 AJW71142.1 - 1.9 8.7 6.5 0.24 11.7 0.4 2.4 2 2 0 2 2 2 0 Zinc finger-containing protein Laminin_II PF06009.12 AJW71142.1 - 2.1 8.3 10.4 11 6.1 5.0 2.6 2 0 0 2 2 2 0 Laminin Domain II Putative_PNPOx PF01243.20 AJW71143.1 - 6.4e-13 48.7 0.0 8.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJW71143.1 - 8.2e-05 22.6 0.0 9.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AJW71143.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like PAC2 PF09754.9 AJW71144.1 - 1.3e-26 94.0 0.0 1.5e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DUF3139 PF11337.8 AJW71144.1 - 0.13 12.9 3.0 0.26 11.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) CBS PF00571.28 AJW71145.1 - 0.005 17.3 0.2 1.4 9.4 0.0 3.5 4 0 0 4 4 4 2 CBS domain Malic_M PF03949.15 AJW71146.1 - 4.3e-26 91.7 4.3 2.3e-25 89.3 4.3 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AJW71146.1 - 1.3e-22 80.5 3.4 1.5e-19 70.5 0.3 3.0 2 1 1 3 3 3 2 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 AJW71146.1 - 4.4e-07 30.0 0.2 1e-06 28.9 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 AJW71146.1 - 7.6e-06 26.1 2.2 4.5e-05 23.6 0.6 2.5 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.21 AJW71146.1 - 2.1e-05 24.4 0.2 4.3e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 AJW71146.1 - 7.8e-05 22.1 0.5 7.8e-05 22.1 0.5 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 AJW71146.1 - 0.00022 20.7 0.3 0.00051 19.5 0.3 1.6 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AJW71146.1 - 0.00097 19.4 0.1 0.003 17.8 0.1 1.9 2 0 0 2 2 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 AJW71146.1 - 0.0048 16.2 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 AJW71146.1 - 0.021 14.4 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 AJW71146.1 - 0.026 14.6 0.7 0.14 12.2 0.1 2.3 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AJW71146.1 - 0.029 13.7 2.1 0.052 12.9 0.4 2.3 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 AJW71146.1 - 0.039 13.3 0.3 0.32 10.3 0.3 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.14 AJW71146.1 - 0.059 12.6 0.2 0.12 11.6 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pribosyltran_N PF13793.6 AJW71146.1 - 0.069 13.1 0.1 0.23 11.4 0.1 1.9 1 1 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase DALR_1 PF05746.15 AJW71147.1 - 3.6e-29 101.4 1.5 9.6e-29 100.0 0.1 2.5 3 0 0 3 3 3 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 AJW71147.1 - 1.5e-25 89.9 4.3 6e-23 81.3 0.3 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 AJW71147.1 - 1.2e-16 61.1 0.2 3.4e-16 59.6 0.2 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 AJW71147.1 - 0.0011 18.4 0.2 0.0029 17.0 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AJW71147.1 - 0.011 14.6 0.1 0.025 13.3 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (M) PNPase PF03726.14 AJW71147.1 - 0.29 11.7 3.3 19 5.8 0.3 3.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Hydrolase_3 PF08282.12 AJW71148.1 - 1.3e-29 103.8 6.0 1.8e-21 77.1 1.8 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AJW71148.1 - 7.3e-07 29.0 0.1 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AJW71148.1 - 9.1e-05 22.8 0.9 0.14 12.4 0.0 2.9 1 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AJW71148.1 - 0.0072 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AJW71148.1 - 0.0078 16.3 0.1 0.042 13.9 0.0 2.2 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AJW71148.1 - 0.012 16.1 0.1 0.23 11.8 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 AJW71148.1 - 0.04 13.5 0.9 12 5.4 0.0 3.0 2 1 1 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) UPF0114 PF03350.16 AJW71149.1 - 3.8 7.7 13.4 0.39 10.9 5.5 3.0 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 MMR_HSR1_Xtn PF16897.5 AJW71151.1 - 4.7e-29 100.5 3.4 9.2e-29 99.6 3.4 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 AJW71151.1 - 2.8e-22 79.0 1.0 5.3e-22 78.1 0.1 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 AJW71151.1 - 6.6e-21 74.1 0.0 1.7e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 AJW71151.1 - 2.4e-15 56.4 2.5 2.7e-13 49.7 0.0 2.4 1 1 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AJW71151.1 - 2.7e-05 24.1 4.4 0.0067 16.4 0.1 2.5 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AJW71151.1 - 0.00016 21.8 0.3 0.28 11.2 0.3 2.7 1 1 0 2 2 2 2 Dynamin family AIG1 PF04548.16 AJW71151.1 - 0.00048 19.5 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Arf PF00025.21 AJW71151.1 - 0.01 15.3 1.9 0.099 12.1 0.1 2.5 2 1 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 AJW71151.1 - 0.014 15.0 3.1 0.076 12.6 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MnmE_helical PF12631.7 AJW71151.1 - 0.063 13.4 0.1 0.082 13.1 0.1 1.1 1 0 0 1 1 1 0 MnmE helical domain SRPRB PF09439.10 AJW71151.1 - 0.065 12.7 0.1 0.065 12.7 0.1 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 AJW71151.1 - 0.13 12.6 1.0 1.1 9.7 0.1 2.5 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 AJW71151.1 - 0.13 12.5 0.4 2.2 8.6 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 AJW71151.1 - 0.22 11.8 0.3 0.45 10.7 0.3 1.5 1 0 0 1 1 1 0 AAA domain DUF1002 PF06207.11 AJW71151.1 - 0.59 9.6 0.1 0.59 9.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1002) Collagen PF01391.18 AJW71153.1 - 7.4e-61 201.8 227.9 5e-09 35.8 32.6 7.6 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) TPR_1 PF00515.28 AJW71154.1 - 2.9e-24 83.8 1.1 1.4e-06 27.9 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJW71154.1 - 2.5e-23 80.3 1.9 5.7e-06 26.0 0.0 5.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 AJW71154.1 - 4e-20 71.2 1.0 2.1e-06 27.3 0.0 4.5 3 1 1 4 4 4 4 TPR repeat TPR_19 PF14559.6 AJW71154.1 - 1.9e-15 57.1 0.1 5.7e-06 26.7 0.0 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AJW71154.1 - 3.6e-15 54.8 5.3 0.0099 16.0 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 AJW71154.1 - 9.3e-15 53.9 0.1 1.7e-05 24.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AJW71154.1 - 5.7e-13 49.3 0.0 0.00033 21.2 0.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJW71154.1 - 1.4e-12 47.3 0.5 0.013 16.2 0.0 5.1 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AJW71154.1 - 1e-08 35.3 0.2 0.0058 16.9 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 AJW71154.1 - 4.9e-07 29.8 0.0 0.00017 21.7 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AJW71154.1 - 5e-07 29.9 0.1 4.4e-06 26.8 0.1 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 AJW71154.1 - 8.1e-05 22.6 0.0 0.59 10.2 0.0 3.7 1 1 2 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 AJW71154.1 - 9.8e-05 22.8 0.2 10 7.0 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_27 PF13463.6 AJW71154.1 - 0.00024 21.5 0.3 0.00078 19.9 0.1 2.0 2 0 0 2 2 1 1 Winged helix DNA-binding domain NARP1 PF12569.8 AJW71154.1 - 0.00036 19.6 1.9 0.014 14.4 0.0 2.3 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 AJW71154.1 - 0.002 18.0 0.2 33 4.8 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 AJW71154.1 - 0.016 15.0 0.1 57 3.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 AJW71154.1 - 0.02 15.2 0.2 3.8 7.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 AJW71154.1 - 0.1 12.7 0.0 3.9 7.6 0.0 2.8 1 1 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Rhodanese PF00581.20 AJW71155.1 - 1.5e-32 112.3 0.0 1.3e-15 57.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NIR_SIR PF01077.22 AJW71156.1 - 4.6e-41 140.0 0.0 2.5e-31 108.3 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AJW71156.1 - 1.5e-30 104.8 0.0 1.7e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Thi4 PF01946.17 AJW71157.1 - 2.1e-65 220.2 0.1 2.5e-65 220.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 AJW71157.1 - 9.3e-14 51.3 0.9 6.7e-07 28.7 0.1 3.0 1 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 AJW71157.1 - 1.1e-09 38.2 0.0 2.7e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AJW71157.1 - 2.5e-08 34.0 0.0 5.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AJW71157.1 - 4.5e-08 32.7 0.0 6.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AJW71157.1 - 1.9e-07 30.7 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AJW71157.1 - 6.7e-07 28.4 0.0 9.8e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 AJW71157.1 - 1.8e-06 27.8 0.5 0.00016 21.4 0.1 2.4 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AJW71157.1 - 1.6e-05 24.3 0.1 2.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AJW71157.1 - 1.8e-05 24.0 0.1 0.00058 19.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 AJW71157.1 - 0.00014 21.1 0.1 0.00022 20.4 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 AJW71157.1 - 0.0065 15.4 0.0 0.88 8.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 AJW71157.1 - 0.0081 16.7 0.1 0.027 15.0 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AJW71157.1 - 0.0086 15.4 0.0 0.023 14.0 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 AJW71157.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase TrkA_N PF02254.18 AJW71157.1 - 0.026 14.8 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GDI PF00996.18 AJW71157.1 - 0.028 13.0 0.0 0.047 12.2 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_9 PF13454.6 AJW71157.1 - 0.047 13.7 0.1 0.089 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Mak16 PF04874.14 AJW71158.1 - 0.17 12.5 1.7 0.31 11.7 0.2 2.0 2 0 0 2 2 2 0 Mak16 protein C-terminal region Ldh_1_N PF00056.23 AJW71159.1 - 1.1e-21 77.5 0.1 1.7e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AJW71159.1 - 3.7e-19 69.3 0.1 5.9e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 AJW71159.1 - 2.7e-05 23.8 0.0 6.4e-05 22.6 0.0 1.6 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase O-antigen_lig PF13425.6 AJW71159.1 - 0.019 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Shikimate_DH PF01488.20 AJW71159.1 - 0.033 14.3 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WbqC PF08889.11 AJW71159.1 - 0.088 12.7 0.1 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 WbqC-like protein family Usp PF00582.26 AJW71160.1 - 3.7e-30 105.3 0.0 4.2e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family SRP54 PF00448.22 AJW71160.1 - 0.01 15.5 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Virulence_fact PF13769.6 AJW71161.1 - 0.036 14.3 0.0 0.51 10.6 0.0 2.1 1 1 0 1 1 1 0 Virulence factor CBS PF00571.28 AJW71162.1 - 3.4e-41 139.5 13.8 4.5e-14 52.6 0.9 4.1 4 0 0 4 4 4 4 CBS domain Usp PF00582.26 AJW71163.1 - 1.9e-29 103.0 0.0 2.1e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 AJW71164.1 - 1.1e-27 97.3 0.0 1.4e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.28 AJW71165.1 - 1.2e-25 89.7 3.0 2.5e-13 50.2 0.3 2.1 2 0 0 2 2 2 2 CBS domain Endonuc-MspI PF09208.10 AJW71165.1 - 0.038 13.4 0.5 0.07 12.5 0.2 1.6 2 0 0 2 2 2 0 Restriction endonuclease MspI Pyr_redox_2 PF07992.14 AJW71166.1 - 3.2e-53 180.9 0.9 3.7e-53 180.7 0.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AJW71166.1 - 1.9e-28 99.6 4.7 9.2e-25 87.5 0.5 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJW71166.1 - 3.2e-19 69.3 2.3 4.6e-18 65.6 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AJW71166.1 - 1.2e-06 27.9 6.5 0.0047 16.1 0.0 4.6 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AJW71166.1 - 2.6e-06 26.9 1.3 0.0074 15.6 0.1 3.1 2 1 1 3 3 3 2 FAD binding domain FAD_binding_2 PF00890.24 AJW71166.1 - 3e-06 26.6 4.7 0.00048 19.3 0.1 3.5 2 1 1 4 4 4 2 FAD binding domain K_oxygenase PF13434.6 AJW71166.1 - 8.5e-06 25.1 0.1 0.04 13.0 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AJW71166.1 - 2e-05 24.0 0.5 0.0023 17.2 0.1 2.5 2 1 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 AJW71166.1 - 7.5e-05 22.2 2.0 0.00085 18.8 0.1 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AJW71166.1 - 0.00015 20.6 3.8 0.026 13.2 0.1 3.9 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_8 PF13450.6 AJW71166.1 - 0.00022 21.4 0.1 0.015 15.6 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 AJW71166.1 - 0.001 19.5 0.1 0.0044 17.5 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 AJW71166.1 - 0.0023 17.6 7.9 1.3 8.5 0.1 3.8 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AJW71166.1 - 0.0038 17.2 1.5 1.4 8.9 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.15 AJW71166.1 - 0.045 12.3 0.8 0.24 9.9 0.1 2.3 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.14 AJW71166.1 - 0.2 10.5 1.2 2.4 6.9 0.2 2.4 3 0 0 3 3 3 0 Tryptophan halogenase PALP PF00291.25 AJW71168.1 - 4.5e-62 210.1 0.0 6.3e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TusA PF01206.17 AJW71169.1 - 1.1e-21 76.4 0.0 1.2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA PHP_C PF13263.6 AJW71170.1 - 1.2e-11 44.1 0.0 2.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 PHP-associated CNPase PF05881.12 AJW71170.1 - 0.00058 19.5 0.0 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) PHP PF02811.19 AJW71170.1 - 0.0067 16.7 0.6 0.0092 16.3 0.7 1.3 1 1 0 1 1 1 1 PHP domain Glyco_tranf_2_4 PF13704.6 AJW71170.1 - 0.057 13.9 0.2 2.7 8.5 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 2 F420_ligase PF01996.16 AJW71171.1 - 4.2e-53 180.2 0.8 4.9e-53 180.0 0.8 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase HAD PF12710.7 AJW71172.1 - 6e-13 49.6 0.0 7.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AJW71172.1 - 1.3e-10 42.0 0.2 1.2e-09 38.8 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AJW71172.1 - 6.5e-05 22.8 0.1 0.0014 18.4 0.2 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase ProRS-C_1 PF09180.11 AJW71174.1 - 5.1e-21 74.6 0.8 5.1e-21 74.6 0.8 2.1 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 AJW71174.1 - 5.3e-21 74.6 0.5 5.3e-21 74.6 0.5 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AJW71174.1 - 2e-18 67.0 0.0 3.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FGE-sulfatase PF03781.16 AJW71175.1 - 9.2e-51 172.9 3.4 2.1e-50 171.7 3.4 1.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 AJW71175.1 - 8.5e-09 36.0 0.1 3.2e-08 34.1 0.1 2.0 1 1 0 1 1 1 1 DinB superfamily DUF4441 PF14536.6 AJW71175.1 - 0.035 14.3 1.3 0.088 13.0 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) DinB PF05163.12 AJW71175.1 - 0.077 12.9 0.5 0.25 11.2 0.2 1.9 1 1 1 2 2 2 0 DinB family ABC_tran PF00005.27 AJW71176.1 - 1.8e-32 112.7 0.0 2.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AJW71176.1 - 3.8e-17 62.6 0.2 9e-17 61.4 0.2 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 AJW71176.1 - 6.9e-06 26.5 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AJW71176.1 - 4.1e-05 23.9 0.5 0.0016 18.7 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AJW71176.1 - 6.1e-05 23.0 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJW71176.1 - 0.00023 20.6 1.1 0.0017 17.8 1.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 AJW71176.1 - 0.0003 21.2 0.4 0.0065 16.9 0.4 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AJW71176.1 - 0.00098 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AJW71176.1 - 0.003 17.3 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AJW71176.1 - 0.0041 16.9 0.0 0.0057 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 AJW71176.1 - 0.0073 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin G-alpha PF00503.20 AJW71176.1 - 0.0096 15.1 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 AJW71176.1 - 0.02 14.3 0.2 0.98 8.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DUF4974 PF16344.5 AJW71176.1 - 0.029 14.4 0.9 0.12 12.4 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4974) TIP49 PF06068.13 AJW71176.1 - 0.032 13.5 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 AJW71176.1 - 0.036 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 AJW71176.1 - 0.042 14.2 0.1 0.099 13.0 0.1 1.8 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 AJW71176.1 - 0.045 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 AJW71176.1 - 0.062 12.4 0.1 0.13 11.3 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein DUF5517 PF17639.2 AJW71176.1 - 0.063 13.6 1.9 2.9 8.3 0.1 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5517) Membralin PF09746.9 AJW71176.1 - 0.069 12.2 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF87 PF01935.17 AJW71176.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_7 PF12775.7 AJW71176.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_13 PF13166.6 AJW71176.1 - 0.078 11.6 0.0 0.96 8.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AJW71176.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AJW71176.1 - 0.083 12.9 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AJW71176.1 - 0.086 13.0 0.1 0.47 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AJW71176.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 AJW71176.1 - 0.091 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 AJW71176.1 - 0.092 13.3 0.1 0.31 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AJW71176.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 AJW71176.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CN_hydrolase PF00795.22 AJW71179.1 - 2.6e-20 72.8 0.0 3.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Inos-1-P_synth PF01658.17 AJW71180.1 - 1.2e-28 99.6 0.1 6.4e-28 97.2 0.0 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase AMP-binding_C_2 PF14535.6 AJW71180.1 - 0.067 13.5 0.1 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DS PF01916.17 AJW71181.1 - 1.3e-89 300.2 0.1 1.6e-89 300.0 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PAC2 PF09754.9 AJW71182.1 - 9.1e-24 84.7 0.0 1e-23 84.5 0.0 1.0 1 0 0 1 1 1 1 PAC2 family LysE PF01810.18 AJW71183.1 - 3.9e-31 108.0 14.3 4.5e-31 107.8 14.3 1.0 1 0 0 1 1 1 1 LysE type translocator GWT1 PF06423.12 AJW71183.1 - 0.26 11.4 6.3 1 9.4 6.3 1.9 1 1 0 1 1 1 0 GWT1 Alba PF01918.21 AJW71185.1 - 2.8e-12 46.2 0.4 3.8e-12 45.8 0.4 1.2 1 0 0 1 1 1 1 Alba Trypan_PARP PF05887.11 AJW71185.1 - 3.3e-08 33.6 125.9 7.5e-06 26.0 58.4 2.2 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 AJW71185.1 - 0.86 10.1 81.1 1.8 9.1 47.0 2.2 1 1 1 2 2 2 0 TonB polyproline region Ndc1_Nup PF09531.10 AJW71185.1 - 5.9 5.5 8.0 7.1 5.2 8.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IMS PF00817.20 AJW71187.1 - 2.4e-41 141.2 0.6 1e-40 139.2 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 AJW71187.1 - 4.8e-11 43.4 0.6 9.7e-11 42.4 0.6 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AJW71187.1 - 4.7e-08 32.9 0.0 1.2e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.6 AJW71187.1 - 0.0023 18.5 0.8 0.17 12.5 0.1 2.4 2 1 1 3 3 3 2 Helix-hairpin-helix domain Cdd1 PF11731.8 AJW71187.1 - 0.0045 17.2 0.1 0.023 14.9 0.0 2.2 2 1 0 2 2 2 1 Pathogenicity locus TfoX_C PF04994.13 AJW71187.1 - 0.029 14.4 1.4 18 5.5 0.0 3.8 3 1 1 4 4 4 0 TfoX C-terminal domain DUF2524 PF10732.9 AJW71187.1 - 0.2 12.0 1.7 0.4 11.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) ZT_dimer PF16916.5 AJW71187.1 - 0.2 11.8 0.4 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter DUF948 PF06103.11 AJW71187.1 - 0.61 10.4 2.6 14 6.0 0.3 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SseC PF04888.12 AJW71187.1 - 4 7.0 5.4 2.4 7.6 1.0 2.5 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family Tmemb_170 PF10190.9 AJW71188.1 - 2 8.8 20.4 0.37 11.2 0.6 3.6 3 0 0 3 3 3 0 Putative transmembrane protein 170 DUF998 PF06197.13 AJW71188.1 - 2.9 7.5 21.2 0.21 11.2 9.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF998) Thioredoxin_4 PF13462.6 AJW71190.1 - 7.4e-31 107.5 0.0 8.8e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AJW71190.1 - 4.4e-16 59.2 0.1 6.2e-14 52.2 0.1 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AJW71190.1 - 0.00032 21.1 0.0 0.00051 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 AJW71190.1 - 0.032 13.9 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Ephrin_lbd PF01404.19 AJW71190.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain zf-C2H2 PF00096.26 AJW71193.1 - 7e-05 23.1 1.1 0.00014 22.1 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 AJW71193.1 - 0.00011 21.9 0.7 0.00018 21.2 0.7 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 AJW71193.1 - 0.0086 16.8 1.1 0.018 15.8 1.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger NAD_binding_2 PF03446.15 AJW71195.1 - 1e-38 133.0 1.5 2.5e-38 131.7 0.6 2.0 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AJW71195.1 - 1.1e-20 74.0 0.1 2e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AJW71195.1 - 7.7e-08 32.8 0.8 2.1e-07 31.4 0.8 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 AJW71195.1 - 1.4e-07 31.3 0.6 3.7e-07 29.9 0.3 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 AJW71195.1 - 1.5e-07 31.0 0.4 2.8e-07 30.1 0.2 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AJW71195.1 - 2e-07 31.1 0.4 3.8e-07 30.2 0.4 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AJW71195.1 - 7.4e-06 25.7 0.3 2e-05 24.3 0.3 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 AJW71195.1 - 2.1e-05 24.6 1.1 0.0014 18.6 1.1 2.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 AJW71195.1 - 0.00011 22.2 0.9 0.00011 22.2 0.9 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AJW71195.1 - 0.0013 19.0 0.2 0.0031 17.8 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 AJW71195.1 - 0.0054 17.2 0.6 0.019 15.4 0.3 2.1 1 1 0 2 2 2 1 Putative NAD(P)-binding Rossmann-like PF10727.9 AJW71195.1 - 0.006 16.4 0.2 0.044 13.6 0.3 2.1 1 1 0 2 2 2 1 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 AJW71195.1 - 0.022 14.3 1.9 0.36 10.4 0.1 2.6 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 AJW71195.1 - 0.043 14.2 0.1 0.088 13.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GFO_IDH_MocA PF01408.22 AJW71195.1 - 0.047 14.5 0.1 0.096 13.5 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short_C2 PF13561.6 AJW71196.1 - 7.4e-67 225.3 0.6 9.2e-67 225.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AJW71196.1 - 2.2e-61 206.7 1.4 3.1e-61 206.3 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AJW71196.1 - 1.4e-07 31.2 0.4 2.6e-07 30.3 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AJW71196.1 - 1.8e-07 31.2 0.4 2.6e-07 30.7 0.4 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AJW71196.1 - 0.0012 18.1 2.6 0.0016 17.6 2.6 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 AJW71196.1 - 0.004 17.1 0.2 0.0071 16.2 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 AJW71196.1 - 0.019 14.0 0.4 0.029 13.4 0.4 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 AJW71196.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 AJW71196.1 - 0.094 12.1 1.6 0.3 10.4 1.6 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 AJW71196.1 - 0.16 12.4 0.9 0.31 11.5 0.9 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF99 PF01949.16 AJW71197.1 - 2.5e-52 176.9 0.0 2.8e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 Saf_2TM PF18303.1 AJW71198.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.0 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF3797 PF12677.7 AJW71199.1 - 0.03 14.2 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) GFA PF04828.14 AJW71199.1 - 0.11 12.9 0.5 0.56 10.6 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF1610 PF07754.11 AJW71199.1 - 0.13 12.3 1.9 0.23 11.4 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) FAD_oxidored PF12831.7 AJW71200.1 - 5.6e-14 52.3 0.0 9.2e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AJW71200.1 - 1.1e-13 51.5 0.3 2.1e-06 27.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AJW71200.1 - 1.8e-11 43.9 0.0 7.1e-11 41.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 AJW71200.1 - 2.9e-11 43.1 0.2 5e-08 32.4 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 AJW71200.1 - 7.4e-10 38.3 0.0 0.00017 20.6 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 AJW71200.1 - 1.5e-08 33.8 0.3 8.4e-08 31.3 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 AJW71200.1 - 1.5e-07 31.0 0.2 2.5e-07 30.2 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AJW71200.1 - 2.6e-07 30.1 1.4 3.3e-07 29.7 0.7 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AJW71200.1 - 1.7e-06 28.2 0.0 3.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AJW71200.1 - 2.6e-06 26.9 1.0 9.7e-06 25.0 1.0 2.0 1 1 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 AJW71200.1 - 2.8e-06 26.7 0.0 5.3e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AJW71200.1 - 6.9e-05 22.2 0.4 0.00013 21.3 0.4 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AJW71200.1 - 0.0026 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AJW71200.1 - 0.0076 16.8 1.1 0.29 11.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AJW71200.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FlgD_ig PF13860.6 AJW71201.1 - 0.0078 16.1 0.0 0.37 10.7 0.0 2.7 2 0 0 2 2 2 1 FlgD Ig-like domain DELLA PF12041.8 AJW71201.1 - 0.031 14.2 1.0 4.7 7.2 0.0 3.8 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal MetOD2 PF18548.1 AJW71201.1 - 0.099 12.8 1.9 0.18 11.9 0.3 2.4 2 0 0 2 2 2 0 Metanogen output domain 2 Cytochrom_B562 PF07361.11 AJW71201.1 - 1.3 9.8 4.9 16 6.2 0.1 4.0 4 0 0 4 4 4 0 Cytochrome b562 Methyltransf_11 PF08241.12 AJW71202.1 - 1.9e-18 66.9 0.0 4.3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW71202.1 - 2.1e-17 63.4 0.0 2.9e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW71202.1 - 4.1e-17 62.7 0.0 1.7e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJW71202.1 - 7.3e-17 61.6 0.2 9.4e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW71202.1 - 2.7e-12 47.3 0.0 4.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AJW71202.1 - 7.6e-10 38.2 0.0 1.2e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 AJW71202.1 - 8.3e-09 35.1 1.7 1.2e-08 34.6 0.8 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 AJW71202.1 - 4.4e-08 33.0 0.0 5.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 AJW71202.1 - 1.6e-07 31.0 0.2 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase DOT1 PF08123.13 AJW71202.1 - 6.1e-07 29.2 0.4 6.2e-06 25.9 0.4 2.1 1 1 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 AJW71202.1 - 2.4e-05 24.0 0.0 5.6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain AdoMet_MTase PF07757.13 AJW71202.1 - 0.00011 22.5 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 AJW71202.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 AJW71202.1 - 0.00038 20.3 0.0 0.00049 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 AJW71202.1 - 0.00043 20.3 0.1 0.00048 20.1 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AJW71202.1 - 0.00054 19.3 0.0 0.00086 18.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 AJW71202.1 - 0.0008 18.9 0.1 0.001 18.5 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 AJW71202.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 AJW71202.1 - 0.014 14.9 0.0 0.074 12.5 0.0 1.9 1 1 1 2 2 2 0 MraW methylase family GidB PF02527.15 AJW71202.1 - 0.025 13.9 0.1 0.042 13.2 0.1 1.4 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G FtsJ PF01728.19 AJW71202.1 - 0.026 14.7 0.0 0.7 10.0 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Paz_1 PF18349.1 AJW71202.1 - 3 7.9 6.6 1.5 8.8 0.5 2.4 2 0 0 2 2 2 0 PAZ domain UPF0052 PF01933.18 AJW71205.1 - 2.8e-57 194.2 0.0 3.2e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CofC PF01983.16 AJW71206.1 - 3.5e-21 75.4 5.3 4.4e-21 75.1 5.3 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 AJW71206.1 - 0.0072 16.7 0.0 0.0082 16.5 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4284 PF14112.6 AJW71206.1 - 0.014 16.3 2.4 0.42 11.6 0.2 2.4 2 1 0 2 2 2 0 Immunity protein 22 TFIIB PF00382.19 AJW71207.1 - 4.4e-36 122.8 5.0 1.6e-18 66.5 1.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW71207.1 - 2.2e-10 39.9 2.7 4e-10 39.1 2.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.16 AJW71207.1 - 0.00033 20.1 0.0 0.17 11.5 0.0 2.8 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_C PF02984.19 AJW71207.1 - 0.0022 18.1 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_AsnC-type PF13404.6 AJW71207.1 - 0.0061 16.4 0.0 0.27 11.1 0.0 2.8 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain Cyclin_N PF00134.23 AJW71207.1 - 0.0069 16.1 0.1 0.064 13.0 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_S27 PF01599.19 AJW71207.1 - 0.007 16.5 1.7 0.016 15.3 1.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a RPW8 PF05659.11 AJW71207.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-ribbon_3 PF13248.6 AJW71207.1 - 0.019 14.4 4.8 0.17 11.4 4.8 2.2 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 AJW71207.1 - 0.05 13.6 1.3 0.12 12.4 1.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon RB_B PF01857.20 AJW71207.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-CCHC_5 PF14787.6 AJW71207.1 - 0.064 13.0 0.4 0.064 13.0 0.4 2.3 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Lar_restr_allev PF14354.6 AJW71207.1 - 0.065 13.6 1.3 0.14 12.5 0.8 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar TPR_5 PF12688.7 AJW71207.1 - 0.15 12.4 1.5 0.36 11.1 0.2 2.2 2 1 0 2 2 2 0 Tetratrico peptide repeat LacI PF00356.21 AJW71207.1 - 0.27 11.0 1.7 1.7 8.5 0.2 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family MerR PF00376.23 AJW71207.1 - 0.4 10.5 1.4 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 MerR family regulatory protein zf-NADH-PPase PF09297.11 AJW71207.1 - 0.65 9.7 8.9 0.83 9.4 0.7 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HTH_36 PF13730.6 AJW71207.1 - 0.8 9.7 3.2 10 6.2 0.3 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain zinc_ribbon_2 PF13240.6 AJW71207.1 - 0.93 9.3 7.9 0.92 9.3 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain CPBP PF02517.16 AJW71208.1 - 5.5e-10 39.5 14.7 5.5e-10 39.5 14.7 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease SUI1 PF01253.22 AJW71209.1 - 3.2e-18 66.0 0.0 4.5e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DTW PF03942.15 AJW71209.1 - 0.017 14.9 0.1 0.017 14.8 0.1 1.1 1 0 0 1 1 1 0 DTW domain Auto_anti-p27 PF06677.12 AJW71210.1 - 3.1e-10 40.0 2.0 4.4e-10 39.6 2.0 1.2 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1178 PF06676.11 AJW71210.1 - 0.052 13.9 0.1 0.066 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Imm3 PF14425.6 AJW71210.1 - 0.094 12.8 0.7 0.13 12.3 0.7 1.2 1 0 0 1 1 1 0 Immunity protein Imm3 Sec61_beta PF03911.16 AJW71211.1 - 1.5e-12 47.3 0.3 1.7e-12 47.1 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family DUF2070 PF09843.9 AJW71212.1 - 3.5e-125 418.5 0.3 4.2e-125 418.2 0.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) MapZ_C2 PF18708.1 AJW71212.1 - 0.033 14.5 0.1 0.094 13.0 0.1 1.7 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 Mrr_cat PF04471.12 AJW71213.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease NERD PF08378.11 AJW71213.1 - 0.048 14.1 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Nuclease-related domain Hjc PF01870.18 AJW71213.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.7 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) SBP_bac_5 PF00496.22 AJW71214.1 - 6.4e-27 94.5 14.6 1.4e-23 83.5 0.0 2.9 3 1 0 3 3 3 2 Bacterial extracellular solute-binding proteins, family 5 Middle Ribo_biogen_C PF04034.13 AJW71215.1 - 5e-37 126.5 0.0 6.5e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 AJW71215.1 - 2.3e-07 30.5 0.1 3.6e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MG2 PF01835.19 AJW71216.1 - 3.9e-26 91.3 8.6 3.6e-05 24.1 0.0 9.1 10 2 0 10 10 10 4 MG2 domain LTD PF00932.19 AJW71216.1 - 1.4e-18 67.3 2.6 3.8e-18 65.9 0.7 2.9 3 0 0 3 3 3 1 Lamin Tail Domain Arrestin_C PF02752.22 AJW71216.1 - 0.0017 18.8 4.6 8.4 6.8 0.0 5.8 6 1 0 6 6 6 1 Arrestin (or S-antigen), C-terminal domain DUF916 PF06030.12 AJW71216.1 - 0.016 15.3 0.2 0.056 13.5 0.2 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) DUF5104 PF17117.5 AJW71216.1 - 5.6 7.4 11.2 6.1 7.3 0.4 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF5104) PG_binding_1 PF01471.18 AJW71221.1 - 0.068 13.4 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DnaJ PF00226.31 AJW71222.1 - 1.6e-16 60.1 0.5 6e-16 58.3 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain DDE_Tnp_1_assoc PF13808.6 AJW71222.1 - 0.0059 16.6 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 DDE_Tnp_1-associated zf-piccolo PF05715.13 AJW71222.1 - 0.097 12.8 2.8 0.38 10.9 2.8 2.0 1 1 0 1 1 1 0 Piccolo Zn-finger 2_5_RNA_ligase2 PF13563.6 AJW71223.1 - 1.4e-15 57.5 0.1 2.3e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.9 AJW71223.1 - 0.0041 17.0 0.1 0.0058 16.5 0.1 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain CAP PF00188.26 AJW71224.1 - 7.6e-16 59.1 2.1 7.6e-16 59.1 2.1 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family A2L_zn_ribbon PF08792.10 AJW71224.1 - 0.039 13.7 1.7 0.039 13.7 1.7 2.7 4 0 0 4 4 4 0 A2L zinc ribbon domain Wzy_C PF04932.15 AJW71224.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase FUN14 PF04930.15 AJW71224.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 FUN14 family TSP_3 PF02412.18 AJW71225.1 - 0.00015 21.4 9.2 0.0057 16.3 0.4 2.9 3 0 0 3 3 3 2 Thrombospondin type 3 repeat Peptidase_M10 PF00413.24 AJW71225.1 - 0.0052 16.6 1.8 0.037 13.9 0.1 2.9 2 1 0 2 2 2 1 Matrixin Reprolysin_3 PF13582.6 AJW71225.1 - 0.013 16.1 0.9 0.061 13.8 0.0 2.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AJW71225.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 FRB_dom PF08771.11 AJW71225.1 - 0.033 14.6 0.3 0.11 12.9 0.3 1.9 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain MG2 PF01835.19 AJW71225.1 - 0.055 13.9 0.1 0.36 11.3 0.0 2.3 3 0 0 3 3 3 0 MG2 domain Reprolysin_4 PF13583.6 AJW71225.1 - 0.059 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DNA_repr_REX1B PF14966.6 AJW71225.1 - 0.22 12.2 2.6 0.77 10.5 1.0 2.2 2 0 0 2 2 2 0 DNA repair REX1-B Peptidase_M43 PF05572.13 AJW71225.1 - 0.49 10.3 0.1 0.49 10.3 0.1 2.6 2 1 1 3 3 3 0 Pregnancy-associated plasma protein-A Ead_Ea22 PF13935.6 AJW71226.1 - 0.27 11.9 1.5 0.36 11.5 0.1 2.0 2 1 0 2 2 2 0 Ead/Ea22-like protein YscO-like PF16789.5 AJW71226.1 - 4.5 7.3 9.3 0.72 9.9 1.5 2.4 2 0 0 2 2 2 0 YscO-like protein DUF3732 PF12532.8 AJW71228.1 - 6.1e-51 172.7 0.6 6.1e-51 172.7 0.6 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF3732) SMC_N PF02463.19 AJW71228.1 - 1e-05 25.1 2.6 3.5e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AJW71228.1 - 5.5e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Fez1 PF06818.15 AJW71228.1 - 0.00057 20.4 12.4 0.00057 20.4 12.4 2.4 2 0 0 2 2 2 1 Fez1 RsgA_GTPase PF03193.16 AJW71228.1 - 0.0013 18.6 0.1 0.0043 17.0 0.1 1.9 1 0 0 1 1 1 1 RsgA GTPase CENP-F_leu_zip PF10473.9 AJW71228.1 - 0.0079 16.2 5.8 0.0079 16.2 5.8 4.4 2 2 1 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_23 PF13476.6 AJW71228.1 - 0.02 15.4 44.7 0.98 9.9 28.3 3.7 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.6 AJW71228.1 - 0.02 14.7 11.6 0.033 14.0 0.0 3.5 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4407 PF14362.6 AJW71228.1 - 0.098 12.0 10.4 0.019 14.3 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) AAA_30 PF13604.6 AJW71228.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 AJW71228.1 - 0.35 10.2 23.9 0.076 12.4 4.2 3.3 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 AJW71228.1 - 0.76 10.3 14.7 0.26 11.8 4.6 3.6 2 2 0 2 2 2 0 ABC transporter Baculo_PEP_C PF04513.12 AJW71228.1 - 1.2 9.2 6.7 0.79 9.8 0.2 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.6 AJW71228.1 - 1.8 8.9 5.3 1.8 8.9 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain BST2 PF16716.5 AJW71228.1 - 4.8 7.8 13.9 0.17 12.5 0.9 3.4 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Myb_DNA-bind_2 PF08914.11 AJW71230.1 - 0.042 14.0 0.2 0.076 13.2 0.2 1.5 1 0 0 1 1 1 0 Rap1 Myb domain Phage_integrase PF00589.22 AJW71232.1 - 9e-14 51.6 0.0 2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Raptor_N PF14538.6 AJW71232.1 - 0.024 14.6 0.5 0.078 12.9 0.5 2.0 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain DZR PF12773.7 AJW71233.1 - 0.0082 16.2 1.4 0.0096 15.9 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon PolC_DP2 PF03833.13 AJW71233.1 - 0.012 13.5 0.3 0.012 13.5 0.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C3HC4_3 PF13920.6 AJW71233.1 - 0.029 14.2 1.3 0.038 13.8 1.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 AJW71233.1 - 0.033 14.3 2.3 0.048 13.8 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF910 PF06014.11 AJW71233.1 - 0.058 13.4 0.2 0.081 12.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) Peptidase_S8 PF00082.22 AJW71235.1 - 4.9e-17 62.1 7.5 1.6e-15 57.2 0.6 5.0 4 2 0 4 4 4 2 Subtilase family HATPase_c PF02518.26 AJW71236.1 - 2.3e-19 69.9 0.0 4.8e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 4HB_MCP_1 PF12729.7 AJW71236.1 - 1.4e-11 44.3 10.6 1.4e-11 44.3 10.6 2.5 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction HisKA PF00512.25 AJW71236.1 - 2.4e-10 40.3 0.3 3e-09 36.8 0.0 2.9 3 1 1 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AJW71236.1 - 8.8e-10 38.8 0.0 8.8e-09 35.6 0.0 2.7 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.6 AJW71236.1 - 8.6e-08 32.0 0.2 6.2e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 AJW71236.1 - 0.0023 17.7 0.1 0.0057 16.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW71236.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF5644 PF18712.1 AJW71236.1 - 0.038 14.0 0.4 0.48 10.5 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5644) TarH PF02203.15 AJW71236.1 - 0.83 9.6 5.4 0.46 10.4 1.2 2.6 1 1 3 4 4 4 0 Tar ligand binding domain homologue Response_reg PF00072.24 AJW71237.1 - 6e-24 84.4 0.5 2.2e-23 82.6 0.5 2.0 1 0 0 1 1 1 1 Response regulator receiver domain TrmB PF01978.19 AJW71237.1 - 1.1e-13 50.8 0.0 2.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 AJW71237.1 - 0.027 13.7 0.9 0.04 13.1 0.3 1.6 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB RFX5_DNA_bdg PF14621.6 AJW71237.1 - 0.28 10.9 1.0 0.41 10.4 1.0 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain DisA-linker PF10635.9 AJW71237.1 - 1.9 8.3 7.1 28 4.5 0.2 3.9 4 1 1 5 5 5 0 DisA bacterial checkpoint controller linker region Peptidase_M24 PF00557.24 AJW71239.1 - 9.3e-32 110.4 0.4 1.2e-31 110.1 0.4 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 HSR PF03172.13 AJW71239.1 - 0.022 14.9 0.1 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 HSR domain SIR2 PF02146.17 AJW71240.1 - 0.032 14.2 1.1 0.036 14.0 1.1 1.0 1 0 0 1 1 1 0 Sir2 family zf-TFIIB PF13453.6 AJW71240.1 - 0.064 12.6 3.7 0.19 11.1 3.7 1.8 1 1 0 1 1 1 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.11 AJW71240.1 - 0.96 9.4 6.6 1.4 8.9 6.6 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DUF1512 PF07431.12 AJW71241.1 - 1.1e-132 442.3 7.0 1.3e-132 442.2 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) V-SNARE PF05008.15 AJW71241.1 - 0.088 13.2 4.1 21 5.6 0.2 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TBP PF00352.21 AJW71242.1 - 1.6e-54 181.8 0.0 5.1e-27 93.7 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 AJW71242.1 - 5.2e-08 32.9 0.0 0.00042 20.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) RTT107_BRCT_5 PF16770.5 AJW71242.1 - 0.075 12.9 0.2 0.26 11.2 0.2 1.8 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain tRNA_bind PF01588.20 AJW71243.1 - 1.8e-22 79.3 0.0 2e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain Polyketide_cyc2 PF10604.9 AJW71246.1 - 2.6e-11 44.0 0.0 2.9e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJW71246.1 - 1.7e-06 28.2 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.11 AJW71246.1 - 0.005 16.7 0.1 0.0059 16.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) MapZ_EC1 PF18041.1 AJW71246.1 - 0.099 12.9 0.1 12 6.1 0.0 2.3 2 1 0 2 2 2 0 MapZ extracellular domain 1 Glycos_transf_2 PF00535.26 AJW71247.1 - 2.4e-27 95.8 0.0 3.4e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJW71247.1 - 1.3e-17 64.5 0.0 1.8e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AJW71247.1 - 1.4e-09 37.7 0.0 2.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 AJW71247.1 - 8.9e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AJW71247.1 - 0.00038 20.9 0.0 0.0007 20.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Trypsin_2 PF13365.6 AJW71248.1 - 2.7e-33 116.0 0.6 5.3e-33 115.0 0.4 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 AJW71248.1 - 8.1e-13 48.7 0.1 2e-12 47.4 0.1 1.6 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 AJW71248.1 - 1.1e-12 48.1 1.8 4.1e-12 46.2 1.8 2.1 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AJW71248.1 - 7.1e-06 25.8 3.5 0.064 13.1 0.1 3.3 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AJW71248.1 - 0.0017 18.7 3.8 0.68 10.3 0.1 3.4 3 0 0 3 3 3 2 PDZ domain Peptidase_S29 PF02907.15 AJW71248.1 - 0.012 15.3 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.21 AJW71248.1 - 0.067 13.0 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease CBM_15 PF03426.14 AJW71248.1 - 0.17 11.5 1.8 4.2 6.9 0.1 2.5 1 1 1 2 2 2 0 Carbohydrate binding domain (family 15) Peptidase_S46 PF10459.9 AJW71248.1 - 0.19 10.3 2.6 0.29 9.8 0.7 1.8 2 0 0 2 2 2 0 Peptidase S46 Radical_SAM PF04055.21 AJW71249.1 - 7.1e-13 49.3 0.0 1.2e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Methyltransf_18 PF12847.7 AJW71249.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.1 3 0 0 3 3 3 0 Methyltransferase domain CdvA PF18822.1 AJW71249.1 - 9.5 6.1 9.9 2.7 7.8 0.1 3.3 4 0 0 4 4 4 0 CdvA-like coiled-coil domain Radical_SAM PF04055.21 AJW71250.1 - 1.6e-21 77.4 0.2 3.3e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily AP_endonuc_2 PF01261.24 AJW71250.1 - 0.015 14.7 0.0 0.17 11.3 0.0 2.3 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Fer4_14 PF13394.6 AJW71250.1 - 0.023 14.8 0.2 0.35 11.0 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF5486 PF17588.2 AJW71250.1 - 0.079 12.9 1.1 6.7 6.7 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5486) MYO10_CC PF16735.5 AJW71250.1 - 0.13 12.4 0.7 9.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain PmbA_TldD PF01523.16 AJW71251.1 - 1.1e-42 146.9 0.5 1.6e-42 146.3 0.5 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase ColG_sub PF18496.1 AJW71251.1 - 0.02 15.1 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Pyr_redox PF00070.27 AJW71251.1 - 0.14 12.7 0.2 1.1 9.9 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Na_Ca_ex PF01699.24 AJW71252.1 - 1.9e-41 141.5 43.1 1e-22 80.8 18.9 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3754 PF12576.8 AJW71252.1 - 4.9 7.1 6.2 0.45 10.4 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) SUa-2TM PF18179.1 AJW71253.1 - 0.043 13.1 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain Zea_mays_MuDR PF05928.11 AJW71253.1 - 0.062 12.9 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Ammonium_transp PF00909.21 AJW71254.1 - 1.8e-114 382.6 33.9 2e-114 382.4 33.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family P-II PF00543.22 AJW71255.1 - 6e-12 46.1 0.4 7.4e-12 45.8 0.4 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II P-II PF00543.22 AJW71258.1 - 2.7e-09 37.5 2.5 5.5e-09 36.6 2.5 1.5 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II DUF4364 PF14277.6 AJW71259.1 - 0.0029 17.4 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_45 PF14947.6 AJW71259.1 - 0.014 15.4 0.2 0.022 14.7 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HMG-CoA_red PF00368.18 AJW71259.1 - 0.17 10.8 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase PAC2 PF09754.9 AJW71260.1 - 6.7e-39 134.1 0.0 7.7e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 PAC2 family AIRS_C PF02769.22 AJW71261.1 - 3.2e-24 85.8 0.0 6.3e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AJW71261.1 - 8.4e-16 58.4 1.9 1.5e-15 57.6 1.9 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Gram_pos_anchor PF00746.21 AJW71262.1 - 0.19 11.7 2.1 0.32 11.0 2.1 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Na_H_Exchanger PF00999.21 AJW71263.1 - 1.2e-60 205.4 52.5 1.6e-60 204.9 52.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PspB PF06667.12 AJW71263.1 - 0.038 14.0 0.0 0.038 14.0 0.0 2.2 2 0 0 2 2 2 0 Phage shock protein B Rab5ip PF07019.12 AJW71263.1 - 0.077 13.6 0.0 0.077 13.6 0.0 4.0 3 2 2 5 5 5 0 Rab5-interacting protein (Rab5ip) DUF4538 PF15061.6 AJW71263.1 - 0.46 10.2 0.1 0.46 10.2 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) HC2 PF07382.11 AJW71264.1 - 1.9e-08 34.6 117.2 1.9e-08 34.6 117.2 2.3 2 1 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Radical_SAM_C PF16199.5 AJW71265.1 - 2.4e-26 91.5 1.2 3.6e-26 91.0 0.3 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 AJW71265.1 - 3.8e-21 76.2 0.0 9.2e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 AJW71265.1 - 1.7e-07 31.5 0.0 4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AJW71265.1 - 1.1e-05 25.4 0.0 3.1e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1f PF01921.18 AJW71266.1 - 9.7e-110 366.9 0.0 1.4e-109 366.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) PolyA_pol_RNAbd PF12627.7 AJW71266.1 - 0.0098 15.6 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA-synt_1g PF09334.11 AJW71266.1 - 0.016 14.0 0.5 0.086 11.6 0.0 2.2 1 1 0 2 2 2 0 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AJW71266.1 - 0.06 12.7 0.1 0.24 10.7 0.0 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Glyco_transf_88 PF16849.5 AJW71266.1 - 0.093 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 88 Uricase PF01014.18 AJW71266.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Uricase Thioredoxin_3 PF13192.6 AJW71266.1 - 0.37 10.9 1.4 0.81 9.8 0.3 2.2 3 0 0 3 3 3 0 Thioredoxin domain Gram_pos_anchor PF00746.21 AJW71267.1 - 1.9 8.5 5.0 11 6.0 0.7 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Spc7 PF08317.11 AJW71268.1 - 0.0029 16.5 55.8 0.089 11.7 16.8 3.0 2 1 1 3 3 3 3 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 AJW71268.1 - 0.0045 17.4 9.1 0.0045 17.4 9.1 3.7 2 1 2 4 4 4 1 Snapin/Pallidin Bap31_Bap29_C PF18035.1 AJW71268.1 - 0.022 14.7 3.7 0.022 14.7 3.7 6.8 4 3 0 5 5 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain EzrA PF06160.12 AJW71268.1 - 0.11 10.7 47.1 0.17 10.0 35.4 2.9 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA QIL1 PF15884.5 AJW71268.1 - 0.15 12.6 4.0 4.5 7.9 0.2 2.6 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 DUF4407 PF14362.6 AJW71268.1 - 0.18 11.1 32.9 0.17 11.2 16.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 AJW71268.1 - 0.22 12.0 41.4 0.79 10.1 11.9 2.5 1 1 1 2 2 2 0 Fez1 Matrilin_ccoil PF10393.9 AJW71268.1 - 0.41 10.5 10.7 7.2 6.6 0.8 3.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ATG16 PF08614.11 AJW71268.1 - 0.46 10.7 43.4 1.5 9.0 19.0 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 AJW71268.1 - 0.7 9.6 28.8 1.3 8.7 8.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 AJW71268.1 - 0.86 9.8 56.3 0.99 9.6 15.4 3.5 2 1 1 3 3 3 0 Tropomyosin like TPR_MLP1_2 PF07926.12 AJW71268.1 - 1.3 9.1 54.0 2 8.5 22.2 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YscO PF07321.12 AJW71268.1 - 2 8.4 37.8 0.056 13.4 10.4 3.3 1 1 2 3 3 3 0 Type III secretion protein YscO Tropomyosin PF00261.20 AJW71268.1 - 3.1 7.1 56.0 1.8 7.9 16.4 3.2 1 1 2 3 3 3 0 Tropomyosin IFT57 PF10498.9 AJW71268.1 - 3.1 6.7 42.7 0.055 12.4 7.6 3.0 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Prp19 PF08606.11 AJW71268.1 - 3.6 7.6 16.1 0.95 9.5 0.1 4.8 3 2 1 4 4 4 0 Prp19/Pso4-like DUF4201 PF13870.6 AJW71268.1 - 6.3 6.5 47.9 2.2 8.0 4.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 AJW71268.1 - 7.4 7.3 51.3 1.8 9.2 8.2 4.2 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Laminin_II PF06009.12 AJW71268.1 - 8.7 6.4 31.9 9.9 6.2 1.9 3.6 2 1 2 4 4 4 0 Laminin Domain II Putative_PNPOx PF01243.20 AJW71269.1 - 2.8e-16 59.5 0.0 3.5e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AJW71269.1 - 0.0034 17.0 0.0 0.0044 16.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like DUF447 PF04289.12 AJW71269.1 - 0.046 13.5 0.0 0.059 13.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF447) DUF3990 PF13151.6 AJW71272.1 - 0.0058 16.3 0.0 0.0073 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Peptidase_S28 PF05577.12 AJW71274.1 - 0.023 13.5 0.1 0.024 13.4 0.1 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ferritin PF00210.24 AJW71275.1 - 6e-39 133.2 2.7 7e-39 133.0 2.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AJW71275.1 - 2.7e-05 24.6 2.2 4.2e-05 24.0 2.2 1.3 1 0 0 1 1 1 1 Rubrerythrin KR PF08659.10 AJW71275.1 - 0.093 12.6 1.3 0.54 10.1 0.2 1.9 1 1 1 2 2 2 0 KR domain DUF1477 PF07346.11 AJW71275.1 - 0.12 12.6 0.2 0.26 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) DUF5357 PF17310.2 AJW71276.1 - 0.7 8.4 7.3 0.069 11.7 1.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5357) DUF4231 PF14015.6 AJW71276.1 - 2.5 8.6 16.9 0.18 12.3 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Pro_CA PF00484.19 AJW71277.1 - 0.0061 16.9 2.4 0.024 14.9 2.4 1.9 1 1 0 1 1 1 1 Carbonic anhydrase Adenine_glyco PF03352.13 AJW71278.1 - 2.2e-79 265.3 0.3 2.8e-79 265.0 0.3 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase CBS PF00571.28 AJW71280.1 - 2.2e-27 95.2 0.1 1.7e-13 50.8 0.0 2.0 2 0 0 2 2 2 2 CBS domain Acetyltransf_10 PF13673.7 AJW71280.1 - 0.085 12.8 0.1 13 5.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DLH PF01738.18 AJW71281.1 - 2e-08 34.1 0.0 2e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 AJW71282.1 - 7.3e-31 107.4 0.0 9.6e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 AJW71282.1 - 1.5e-06 27.5 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 AJW71282.1 - 8.9e-06 24.8 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme BAAT_C PF08840.11 AJW71282.1 - 0.0002 21.4 0.1 0.00034 20.6 0.1 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 AJW71282.1 - 0.0033 17.1 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AJW71282.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ScdA_N PF04405.14 AJW71282.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) SHOCT PF09851.9 AJW71283.1 - 3.2e-05 23.5 3.3 3.2e-05 23.5 3.3 2.5 3 0 0 3 3 3 1 Short C-terminal domain ATP-synt_B PF00430.18 AJW71283.1 - 0.017 15.2 2.8 0.027 14.6 2.8 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) YtxH PF12732.7 AJW71283.1 - 0.56 10.8 13.0 0.44 11.1 7.7 2.8 2 1 0 2 2 2 0 YtxH-like protein CBS PF00571.28 AJW71285.1 - 1.5e-38 131.0 5.4 4.5e-11 43.0 0.1 4.2 4 0 0 4 4 4 4 CBS domain PduV-EutP PF10662.9 AJW71285.1 - 0.15 11.8 1.2 2.3 7.9 0.1 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CBS PF00571.28 AJW71286.1 - 6e-06 26.6 0.1 6e-06 26.6 0.1 1.2 1 1 0 1 1 1 1 CBS domain Aminotran_1_2 PF00155.21 AJW71287.1 - 2e-40 139.1 0.0 3.8e-40 138.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJW71287.1 - 0.051 12.1 0.0 0.11 11.0 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HATPase_c PF02518.26 AJW71289.1 - 2e-15 57.2 1.8 2.4e-15 57.0 0.1 2.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW71289.1 - 3.2e-08 33.5 0.1 6.9e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW71289.1 - 4.9e-05 23.2 0.0 4.9e-05 23.2 0.0 2.6 3 1 0 3 3 3 1 GHKL domain DivIC PF04977.15 AJW71289.1 - 0.071 12.9 2.6 0.082 12.7 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator KNTase_C PF07827.11 AJW71289.1 - 0.083 12.7 0.5 9.5 6.1 0.1 2.3 1 1 1 2 2 2 0 KNTase C-terminal domain DUF2397 PF09660.10 AJW71289.1 - 0.3 10.0 0.7 0.38 9.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) DUF5595 PF18077.1 AJW71289.1 - 3.2 7.9 7.0 1.3 9.2 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Fib_alpha PF08702.10 AJW71289.1 - 8.1 6.6 16.8 5.4 7.2 6.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Response_reg PF00072.24 AJW71290.1 - 1.9e-20 73.1 0.5 2.2e-20 72.9 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AJW71290.1 - 0.13 12.7 0.1 0.18 12.2 0.1 1.3 1 1 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c PF02518.26 AJW71291.1 - 1.2e-30 106.3 0.3 2.5e-30 105.3 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW71291.1 - 4.2e-16 58.7 0.2 8.4e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PorA PF11271.8 AJW71291.1 - 3.2e-10 39.8 0.1 6e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Porin PorA HATPase_c_3 PF13589.6 AJW71291.1 - 0.0063 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Skp1_POZ PF03931.15 AJW71291.1 - 0.028 14.6 0.0 0.096 12.9 0.0 1.9 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Phage_min_cap2 PF06152.11 AJW71291.1 - 0.26 10.2 1.8 0.37 9.6 1.8 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 ABC_sub_bind PF04392.12 AJW71292.1 - 2.7e-47 161.4 10.4 3.2e-47 161.2 10.4 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein ToxN_toxin PF13958.6 AJW71292.1 - 0.08 13.2 0.7 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system HATPase_c PF02518.26 AJW71293.1 - 3.4e-22 79.1 0.0 1.8e-21 76.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW71293.1 - 6e-11 42.2 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW71293.1 - 3.5e-06 26.9 0.0 1.1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AJW71293.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AJW71293.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ykof PF07615.11 AJW71293.1 - 0.13 12.8 0.0 0.53 10.8 0.0 2.0 1 0 0 1 1 1 0 YKOF-related Family Lipoprotein_17 PF04200.12 AJW71293.1 - 0.14 12.6 3.7 0.67 10.3 3.7 2.2 1 0 0 1 1 1 0 Lipoprotein associated domain Phage_holin_6_1 PF09682.10 AJW71293.1 - 0.17 12.3 5.5 1.7 9.1 0.6 3.0 2 1 1 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DnaJ_CXXCXGXG PF00684.19 AJW71294.1 - 0.0015 18.9 1.4 0.0018 18.6 1.4 1.2 1 0 0 1 1 1 1 DnaJ central domain FAM76 PF16046.5 AJW71294.1 - 0.018 14.4 1.2 0.018 14.4 1.2 1.0 1 0 0 1 1 1 0 FAM76 protein TatC PF00902.18 AJW71295.1 - 0.18 11.6 7.4 0.19 11.5 7.4 1.0 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) zf-C2H2 PF00096.26 AJW71296.1 - 1.7e-06 28.2 5.7 0.0025 18.2 0.5 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJW71296.1 - 6.1e-06 26.6 8.3 0.021 15.6 1.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 AJW71296.1 - 0.00012 21.8 4.7 0.022 14.5 0.6 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 AJW71296.1 - 0.00018 21.4 11.6 0.015 15.3 1.8 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 AJW71296.1 - 0.00045 20.9 1.8 0.47 11.1 0.1 2.0 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats RNA_POL_M_15KD PF02150.16 AJW71296.1 - 0.0024 17.7 2.4 0.27 11.2 0.2 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zinc_ribbon_4 PF13717.6 AJW71296.1 - 0.0037 17.1 5.4 0.18 11.8 0.3 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DUF678 PF05077.12 AJW71296.1 - 0.0082 16.3 0.7 1.9 8.6 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF678) zf-C2H2_8 PF15909.5 AJW71296.1 - 0.0089 16.3 7.0 0.69 10.2 2.9 2.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon DNA_RNApol_7kD PF03604.13 AJW71296.1 - 0.0095 15.6 3.1 0.2 11.3 0.2 2.5 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.6 AJW71296.1 - 0.011 15.7 4.0 0.13 12.2 0.6 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-trcl PF13451.6 AJW71296.1 - 0.012 15.5 3.6 1.7 8.6 0.7 2.4 2 1 0 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 AJW71296.1 - 0.012 16.3 5.8 0.015 16.0 5.8 1.3 1 1 0 1 1 1 0 zinc-ribbon family zinc_ribbon_5 PF13719.6 AJW71296.1 - 0.016 14.9 4.3 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.12 AJW71296.1 - 0.018 14.8 1.4 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 HypF finger Lar_restr_allev PF14354.6 AJW71296.1 - 0.021 15.2 4.0 0.026 14.9 4.0 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-DNA_Pol PF08996.10 AJW71296.1 - 0.021 14.6 3.5 0.025 14.3 3.5 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Zn-ribbon_8 PF09723.10 AJW71296.1 - 0.024 14.8 4.9 0.024 14.8 4.9 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-CSL PF05207.13 AJW71296.1 - 0.038 13.7 3.4 2.6 7.9 0.3 2.1 1 1 1 2 2 2 0 CSL zinc finger FYVE PF01363.21 AJW71296.1 - 0.043 13.9 9.1 0.064 13.4 4.6 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.6 AJW71296.1 - 0.046 13.1 1.6 3.8 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.8 AJW71296.1 - 0.047 13.6 1.0 7.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TFIIS_C PF01096.18 AJW71296.1 - 0.048 13.5 2.2 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) ADK_lid PF05191.14 AJW71296.1 - 0.049 13.6 4.5 0.11 12.5 1.5 2.1 1 1 1 2 2 2 0 Adenylate kinase, active site lid HypA PF01155.19 AJW71296.1 - 0.061 13.3 6.5 0.06 13.4 3.4 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AJW71296.1 - 0.08 13.0 6.3 0.16 12.0 6.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 AJW71296.1 - 0.099 12.3 3.2 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 AJW71296.1 - 0.11 12.0 3.0 2.4 7.8 0.4 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Ephrin_rec_like PF07699.13 AJW71296.1 - 0.11 12.3 4.4 0.99 9.2 0.5 2.1 1 1 1 2 2 2 0 Putative ephrin-receptor like PhnA_Zn_Ribbon PF08274.12 AJW71296.1 - 0.11 12.4 1.0 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-C2HC_2 PF13913.6 AJW71296.1 - 0.12 12.3 16.0 4.7 7.2 7.1 2.7 1 1 1 2 2 2 0 zinc-finger of a C2HC-type Rubredoxin_2 PF18073.1 AJW71296.1 - 0.15 11.8 4.6 2.7 7.8 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-Sec23_Sec24 PF04810.15 AJW71296.1 - 0.18 11.9 2.3 2.9 8.0 0.1 2.3 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger DUF983 PF06170.12 AJW71296.1 - 0.21 12.0 2.8 2.5 8.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Zn_ribbon_recom PF13408.6 AJW71296.1 - 0.24 11.9 6.2 1.5 9.4 6.2 2.0 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-ACC PF17848.1 AJW71296.1 - 0.31 11.1 14.3 0.31 11.1 2.8 3.3 2 2 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_3 PF13878.6 AJW71296.1 - 0.37 10.7 9.4 3.9 7.4 4.6 2.5 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO OrfB_Zn_ribbon PF07282.11 AJW71296.1 - 0.41 10.6 6.7 4.4 7.3 6.8 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain XPA_N PF01286.18 AJW71296.1 - 0.49 10.5 7.8 3.1 7.9 0.2 2.6 3 0 0 3 3 3 0 XPA protein N-terminal zf-H2C2_2 PF13465.6 AJW71296.1 - 0.8 10.2 13.8 2 9.0 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double domain DUF5472 PF17566.2 AJW71296.1 - 1.6 8.8 4.3 13 5.9 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5472) zf-C2HE PF16278.5 AJW71296.1 - 1.9 9.0 12.4 2.4 8.6 1.7 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CCHC_6 PF15288.6 AJW71296.1 - 3.7 7.5 13.6 0.89 9.5 1.8 2.7 2 1 1 3 3 3 0 Zinc knuckle RibD_C PF01872.17 AJW71297.1 - 2.2e-14 53.8 0.2 3.8e-12 46.4 0.2 2.1 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 AJW71297.1 - 8.9e-08 32.0 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Spc29 PF17082.5 AJW71299.1 - 0.021 14.7 6.3 0.17 11.7 1.1 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF5638 PF18688.1 AJW71299.1 - 0.043 14.1 8.3 0.042 14.1 3.2 2.4 1 1 2 3 3 3 0 Family of unknown function (DUF5638) CagY_I PF14585.6 AJW71299.1 - 0.049 13.7 1.9 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 CagY type 1 repeat DUF445 PF04286.12 AJW71299.1 - 0.056 13.3 6.3 0.07 12.9 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Inhibitor_I34 PF10466.9 AJW71299.1 - 0.1 13.2 5.7 0.99 10.1 1.4 2.7 2 1 0 2 2 2 0 Saccharopepsin inhibitor I34 Noelin-1 PF12308.8 AJW71299.1 - 0.16 12.0 7.4 2.6 8.1 0.6 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein Imm3 PF14425.6 AJW71299.1 - 0.17 12.0 4.1 0.28 11.2 4.1 1.5 1 1 0 1 1 1 0 Immunity protein Imm3 YpjP PF14005.6 AJW71299.1 - 0.24 11.4 4.6 0.23 11.5 3.2 1.7 1 1 1 2 2 2 0 YpjP-like protein Sec20 PF03908.13 AJW71299.1 - 6 6.9 10.1 0.61 10.0 2.1 2.2 2 0 0 2 2 2 0 Sec20 MIP PF00230.20 AJW71300.1 - 1.6e-53 181.7 19.0 1.9e-53 181.5 19.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ldr_toxin PF13940.6 AJW71300.1 - 0.0073 16.3 0.9 0.023 14.7 0.9 1.9 1 0 0 1 1 1 1 Toxin Ldr, type I toxin-antitoxin system AhpC-TSA PF00578.21 AJW71301.1 - 3.4e-40 136.8 0.1 3.9e-40 136.6 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJW71301.1 - 3.6e-27 94.9 0.1 3.9e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AJW71301.1 - 6.7e-08 32.6 0.1 1.2e-07 31.8 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AJW71301.1 - 3.8e-07 29.8 0.0 4.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.14 AJW71301.1 - 0.00016 21.6 0.1 0.00026 20.9 0.1 1.4 1 1 0 1 1 1 1 SCO1/SenC UbiD PF01977.16 AJW71303.1 - 1.5e-155 518.1 0.0 1.7e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DNA_methylase PF00145.17 AJW71303.1 - 0.17 11.2 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Radical_SAM PF04055.21 AJW71304.1 - 2.3e-17 63.9 0.0 4.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF905 PF06006.12 AJW71304.1 - 0.044 13.8 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) DeoC PF01791.9 AJW71305.1 - 7.6e-48 163.2 0.0 9.1e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHQS PF01959.16 AJW71306.1 - 1.4e-104 349.8 0.2 1.7e-104 349.6 0.2 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase II CppA_N PF14506.6 AJW71306.1 - 0.031 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 CppA N-terminal Skp1 PF01466.19 AJW71306.1 - 0.18 11.9 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DHquinase_I PF01487.15 AJW71307.1 - 4.6e-54 184.1 0.0 5.2e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase Ribosomal_S24e PF01282.19 AJW71307.1 - 0.023 14.6 0.1 0.064 13.2 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S24e HERV-K_REC PF15695.5 AJW71307.1 - 0.64 10.1 4.2 2 8.5 0.2 2.8 2 1 0 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Shikimate_dh_N PF08501.11 AJW71308.1 - 8.5e-27 93.2 0.0 2.4e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AJW71308.1 - 2.8e-13 49.4 0.5 4.7e-13 48.7 0.5 1.4 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AJW71308.1 - 2.6e-12 47.0 1.5 3.6e-12 46.5 0.8 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AJW71308.1 - 3e-05 24.3 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AJW71308.1 - 0.0053 17.3 0.6 0.0091 16.6 0.6 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 AJW71308.1 - 0.0086 16.5 0.1 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding GARS_N PF02844.15 AJW71308.1 - 0.13 13.1 0.4 0.28 12.0 0.4 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain GHMP_kinases_N PF00288.26 AJW71309.1 - 9.1e-10 38.6 0.3 2.1e-09 37.4 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJW71309.1 - 1.6e-05 25.2 0.0 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal DUF3560 PF12083.8 AJW71309.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) EPSP_synthase PF00275.20 AJW71310.1 - 6.2e-101 338.1 0.0 7.6e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TubC_N PF18563.1 AJW71310.1 - 0.03 14.3 0.3 1.4 8.9 0.0 3.2 3 0 0 3 3 3 0 TubC N-terminal docking domain HATPase_c PF02518.26 AJW71311.1 - 4.9e-19 68.9 0.1 5.3e-19 68.8 0.1 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AJW71311.1 - 5.3e-08 32.7 0.0 6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AJW71311.1 - 6.8e-05 22.7 0.1 7.9e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW71311.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_9 PF13426.7 AJW71312.1 - 5.6e-13 49.0 0.0 5.6e-13 49.0 0.0 2.2 3 0 0 3 3 1 1 PAS domain HisKA PF00512.25 AJW71312.1 - 3.2e-10 39.9 0.2 8.7e-10 38.5 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AJW71312.1 - 1e-09 38.4 0.0 2.5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AJW71312.1 - 1.6e-08 34.7 0.5 4.8e-08 33.2 0.5 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AJW71312.1 - 1.8e-05 25.0 0.0 3.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AJW71312.1 - 0.00025 21.0 0.0 0.00085 19.3 0.0 1.9 2 0 0 2 2 2 1 PAS domain Lectin_N PF03954.14 AJW71312.1 - 0.0026 17.5 2.0 0.085 12.6 1.5 2.5 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.6 AJW71312.1 - 0.0039 17.5 1.9 0.0039 17.5 1.9 3.2 3 1 0 3 3 3 1 Syntaxin-like protein GrpE PF01025.19 AJW71312.1 - 0.021 14.5 4.6 0.92 9.2 0.2 2.6 2 0 0 2 2 2 0 GrpE CHASE3 PF05227.13 AJW71312.1 - 0.025 14.5 0.7 14 5.6 0.1 3.2 3 0 0 3 3 3 0 CHASE3 domain Tup_N PF08581.10 AJW71312.1 - 1.1 9.6 7.2 4.4 7.7 0.5 3.5 3 0 0 3 3 3 0 Tup N-terminal Syntaxin-6_N PF09177.11 AJW71312.1 - 1.3 9.6 7.7 0.69 10.5 0.3 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal AI-2E_transport PF01594.16 AJW71312.1 - 2 7.5 6.0 1.4 8.0 0.9 2.4 1 1 2 3 3 3 0 AI-2E family transporter Sigma_reg_N PF13800.6 AJW71312.1 - 4.3 7.7 11.2 5.4 7.4 0.3 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Chorismate_synt PF01264.21 AJW71313.1 - 7e-135 448.9 0.3 8.1e-135 448.7 0.3 1.0 1 0 0 1 1 1 1 Chorismate synthase BCIP PF13862.6 AJW71313.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Aminotran_1_2 PF00155.21 AJW71314.1 - 5.2e-57 193.7 0.0 6.8e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CM_2 PF01817.21 AJW71314.1 - 3.2e-11 43.4 0.5 1.1e-10 41.8 0.5 2.0 1 0 0 1 1 1 1 Chorismate mutase type II Aminotran_5 PF00266.19 AJW71314.1 - 4e-06 26.0 0.0 5.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AJW71314.1 - 3.4e-05 23.3 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AJW71314.1 - 6e-05 21.7 0.1 9.6e-05 21.1 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme LppX_LprAFG PF07161.13 AJW71314.1 - 0.0039 17.1 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 LppX_LprAFG lipoprotein PET122 PF05476.11 AJW71314.1 - 0.021 14.2 0.1 0.051 12.9 0.1 1.6 1 1 0 1 1 1 0 PET122 Beta_elim_lyase PF01212.21 AJW71314.1 - 0.031 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase PDH PF02153.17 AJW71315.1 - 5.8e-24 84.5 0.4 6.9e-24 84.2 0.4 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 AJW71315.1 - 1.1e-05 24.9 0.0 2.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AJW71315.1 - 2e-05 24.8 0.6 0.00012 22.2 0.0 2.3 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AJW71315.1 - 0.00028 20.8 1.2 0.00071 19.5 0.0 2.1 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AJW71315.1 - 0.00031 21.3 0.2 0.0031 18.0 0.0 2.8 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 AJW71315.1 - 0.002 18.1 1.1 1.6 8.7 0.0 3.4 2 1 1 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2529 PF10740.9 AJW71315.1 - 0.0084 15.8 0.6 0.39 10.4 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF2529) Semialdhyde_dh PF01118.24 AJW71315.1 - 0.013 15.9 0.1 0.85 10.1 0.0 3.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 AJW71315.1 - 0.021 15.0 0.1 0.094 12.8 0.0 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 AJW71315.1 - 0.026 14.0 0.0 0.077 12.4 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 AJW71315.1 - 0.027 14.6 0.3 1.8 8.6 0.1 2.8 2 2 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 AJW71315.1 - 0.033 14.7 0.1 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain KxDL PF10241.9 AJW71315.1 - 0.04 14.2 0.1 0.09 13.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF1392 PF07154.11 AJW71315.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1392) DpaA_N PF16924.5 AJW71315.1 - 0.059 13.5 0.1 0.42 10.7 0.0 2.3 1 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain adh_short PF00106.25 AJW71315.1 - 0.1 12.1 1.2 5.9 6.3 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase NUDIX PF00293.28 AJW71316.1 - 1.2e-11 44.8 0.1 1.3e-11 44.6 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AJW71316.1 - 2.6e-05 24.1 0.0 3.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain ThiC_Rad_SAM PF01964.18 AJW71317.1 - 2.9e-172 573.2 0.6 3.4e-172 572.9 0.6 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family DUF3006 PF11213.8 AJW71317.1 - 0.15 12.3 1.5 10 6.5 0.1 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3006) KLRAQ PF10205.9 AJW71318.1 - 0.0052 17.0 1.0 0.0052 17.0 1.0 1.3 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein Packaging_FI PF14000.6 AJW71318.1 - 0.0096 16.4 0.1 0.01 16.3 0.1 1.2 1 0 0 1 1 1 1 DNA packaging protein FI DUF3450 PF11932.8 AJW71318.1 - 0.045 13.0 1.0 0.048 12.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2205 PF10224.9 AJW71318.1 - 0.054 13.5 5.5 0.83 9.7 0.3 3.0 1 1 2 3 3 3 0 Short coiled-coil protein HALZ PF02183.18 AJW71318.1 - 0.062 13.5 4.6 0.11 12.7 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 AJW71318.1 - 0.14 12.6 3.2 3.2 8.2 3.2 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 AJW71318.1 - 0.32 10.8 4.5 0.26 11.1 1.9 2.0 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 AJW71318.1 - 0.32 11.1 0.2 0.32 11.1 0.2 2.4 2 1 1 3 3 3 0 Basic region leucine zipper Phos_pyr_kin PF08543.12 AJW71319.1 - 7.4e-71 238.4 3.6 1.4e-70 237.4 3.6 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ThiP_synth PF10120.9 AJW71319.1 - 2.6e-55 186.5 0.0 4.6e-55 185.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine-phosphate synthase PfkB PF00294.24 AJW71319.1 - 1e-12 48.0 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 AJW71319.1 - 3.7e-05 23.3 0.2 7.5e-05 22.3 0.2 1.6 1 1 0 1 1 1 1 Carbohydrate kinase Bac_small_YrzI PF09501.10 AJW71319.1 - 9 6.5 7.6 0.49 10.6 0.5 2.6 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) NTP_transferase PF00483.23 AJW71320.1 - 4.5e-39 134.5 0.0 5e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJW71320.1 - 1.1e-09 38.8 0.0 1.3e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 AJW71320.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase TPP_enzyme_C PF02775.21 AJW71320.1 - 0.03 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IspD PF01128.19 AJW71320.1 - 0.032 14.0 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Acetyltransf_1 PF00583.25 AJW71321.1 - 2.2e-18 66.6 0.0 2.6e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AJW71321.1 - 5.7e-15 55.4 0.0 6.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJW71321.1 - 3.7e-13 49.7 0.1 5.6e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AJW71321.1 - 1.9e-05 24.7 0.0 2.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJW71321.1 - 0.042 13.8 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 AJW71321.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2162 PF09930.9 AJW71322.1 - 0.0008 18.9 0.2 0.0008 18.9 0.2 2.0 1 1 0 2 2 2 1 Predicted transporter (DUF2162) DUF2663 PF10864.8 AJW71322.1 - 0.017 15.5 1.5 2.4 8.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) DUF975 PF06161.11 AJW71322.1 - 0.48 10.2 5.8 0.48 10.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF975) DUF3188 PF11384.8 AJW71322.1 - 0.51 10.1 4.3 0.67 9.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF2207 PF09972.9 AJW71322.1 - 0.92 8.2 3.8 12 4.5 3.8 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) GalP_UDP_transf PF01087.22 AJW71323.1 - 3.5e-10 40.6 0.0 8.6e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 AJW71323.1 - 1.4e-05 24.1 0.0 1.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4921) HIT PF01230.23 AJW71323.1 - 7.7e-05 23.4 0.0 0.0013 19.4 0.0 2.2 2 0 0 2 2 2 1 HIT domain GalP_UDP_tr_C PF02744.17 AJW71323.1 - 0.00026 20.8 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain PhosphMutase PF10143.9 AJW71324.1 - 1.5e-43 148.6 0.0 3.4e-43 147.5 0.0 1.6 2 0 0 2 2 2 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 AJW71324.1 - 2.2e-26 92.7 0.4 3e-26 92.3 0.4 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 AJW71324.1 - 0.00082 19.1 0.0 0.0041 16.8 0.0 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 AJW71324.1 - 0.031 13.2 0.1 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Alkaline phosphatase DUF309 PF03745.14 AJW71325.1 - 1.6e-17 62.9 1.1 3.2e-17 62.0 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF309) Ribosomal_S24e PF01282.19 AJW71326.1 - 4.2e-06 26.6 0.1 6.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S27 PF01599.19 AJW71327.1 - 9.1e-22 77.0 6.3 1.1e-21 76.7 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a Ribosomal_L37e PF01907.19 AJW71327.1 - 0.0015 18.7 1.6 0.0022 18.1 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DUF1451 PF07295.11 AJW71327.1 - 0.0061 16.6 0.8 0.0061 16.6 0.8 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain GFA PF04828.14 AJW71327.1 - 0.011 16.0 2.4 0.049 14.0 0.9 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 AJW71327.1 - 0.022 14.7 5.6 0.21 11.6 5.0 2.3 1 1 1 2 2 2 0 Nudix N-terminal G5 PF07501.12 AJW71327.1 - 0.035 14.5 0.1 0.041 14.3 0.1 1.1 1 0 0 1 1 1 0 G5 domain OrfB_Zn_ribbon PF07282.11 AJW71327.1 - 0.039 13.9 1.9 0.055 13.4 1.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_11 PF11682.8 AJW71327.1 - 0.064 13.3 0.2 0.064 13.3 0.2 1.5 1 1 1 2 2 2 0 Probable zinc-ribbon zf_UBZ PF18439.1 AJW71327.1 - 2 8.1 7.5 1.1 8.9 1.5 2.4 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger SprT-like PF10263.9 AJW71328.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Ada3 PF10198.9 AJW71329.1 - 0.034 14.3 0.4 0.038 14.1 0.4 1.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 BrnA_antitoxin PF14384.6 AJW71329.1 - 0.12 12.9 0.9 0.18 12.3 0.9 1.3 1 1 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system HTH_45 PF14947.6 AJW71330.1 - 1.5e-12 47.3 3.9 2.5e-12 46.6 3.9 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HSP33 PF01430.19 AJW71330.1 - 0.038 13.4 0.3 0.043 13.2 0.3 1.1 1 0 0 1 1 1 0 Hsp33 protein HemN_C PF06969.16 AJW71330.1 - 0.04 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain Rrf2 PF02082.20 AJW71330.1 - 0.13 12.7 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator MEDS PF14417.6 AJW71331.1 - 6.8e-14 52.0 0.0 8.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF2703 PF10865.8 AJW71332.1 - 0.00043 20.4 0.6 0.0022 18.2 0.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2703) THUMP PF02926.17 AJW71332.1 - 0.0011 19.1 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 THUMP domain zf-FCS PF06467.14 AJW71332.1 - 0.29 11.1 7.0 1.2 9.1 0.3 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif SRP54 PF00448.22 AJW71333.1 - 4e-69 232.2 0.1 7.7e-69 231.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AJW71333.1 - 4.1e-27 94.7 1.2 4.1e-27 94.7 1.2 2.5 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 AJW71333.1 - 1.4e-17 63.7 1.2 1.4e-17 63.7 1.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AJW71333.1 - 4.1e-07 30.1 0.0 1.2e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AJW71333.1 - 9.8e-05 21.9 0.1 0.00017 21.1 0.1 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_17 PF13207.6 AJW71333.1 - 0.00014 22.3 1.2 0.0011 19.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 AJW71333.1 - 0.00017 20.7 0.0 0.0016 17.5 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 AJW71333.1 - 0.00028 20.8 0.2 0.00065 19.6 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 AJW71333.1 - 0.00032 20.6 0.5 0.0011 18.9 0.1 2.1 3 0 0 3 3 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 AJW71333.1 - 0.0004 20.9 0.2 0.0027 18.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 AJW71333.1 - 0.0005 19.7 0.9 0.0035 17.0 0.9 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AJW71333.1 - 0.00063 20.0 0.3 0.0023 18.2 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 AJW71333.1 - 0.001 19.5 0.0 0.0064 16.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 AJW71333.1 - 0.0013 18.7 0.3 0.0041 17.1 0.2 1.8 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.10 AJW71333.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 PduV-EutP PF10662.9 AJW71333.1 - 0.0024 17.6 0.6 1 9.1 0.2 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_26 PF13500.6 AJW71333.1 - 0.003 17.4 0.0 0.77 9.6 0.3 2.8 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 AJW71333.1 - 0.0035 16.7 0.0 0.0085 15.4 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin Thymidylate_kin PF02223.17 AJW71333.1 - 0.0041 16.8 0.3 0.012 15.2 0.3 1.7 1 0 0 1 1 1 1 Thymidylate kinase ResIII PF04851.15 AJW71333.1 - 0.0057 16.7 0.5 0.02 14.9 0.1 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 AJW71333.1 - 0.0061 16.5 1.4 0.0091 15.9 0.5 1.9 2 1 0 2 2 1 1 NTPase AAA_33 PF13671.6 AJW71333.1 - 0.0079 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AJW71333.1 - 0.0094 15.7 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 AJW71333.1 - 0.0097 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_5 PF07728.14 AJW71333.1 - 0.0098 15.9 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 AJW71333.1 - 0.01 15.9 0.3 0.048 13.8 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 AJW71333.1 - 0.01 15.5 0.1 0.03 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AJW71333.1 - 0.011 16.2 0.2 0.029 14.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain MipZ PF09140.11 AJW71333.1 - 0.011 15.0 0.4 0.5 9.6 0.4 2.3 1 1 0 1 1 1 0 ATPase MipZ Arf PF00025.21 AJW71333.1 - 0.016 14.7 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family G-alpha PF00503.20 AJW71333.1 - 0.016 14.4 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit LpxK PF02606.14 AJW71333.1 - 0.017 14.2 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase IstB_IS21 PF01695.17 AJW71333.1 - 0.019 14.7 0.2 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 AJW71333.1 - 0.02 15.4 0.0 0.057 13.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 AJW71333.1 - 0.024 14.1 0.3 0.27 10.6 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 AJW71333.1 - 0.028 14.2 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LytR_C PF13399.6 AJW71333.1 - 0.039 14.9 0.0 0.12 13.4 0.0 2.0 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator SpoVIF PF14069.6 AJW71333.1 - 0.048 13.4 0.2 0.16 11.8 0.2 2.0 1 0 0 1 1 1 0 Stage VI sporulation protein F AAA_28 PF13521.6 AJW71333.1 - 0.059 13.6 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 AJW71333.1 - 0.061 13.1 0.0 0.2 11.4 0.0 2.0 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 AJW71333.1 - 0.069 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein NACHT PF05729.12 AJW71333.1 - 0.23 11.4 1.9 0.29 11.1 0.4 1.9 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 AJW71333.1 - 0.26 10.8 2.0 1.1 8.9 2.0 2.0 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 AJW71333.1 - 0.49 9.5 2.4 1 8.5 0.4 2.5 3 0 0 3 3 3 0 Anion-transporting ATPase Diphthami_syn_2 PF01902.17 AJW71334.1 - 1.8e-51 174.7 0.0 2.2e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase QueC PF06508.13 AJW71334.1 - 0.002 17.7 0.0 0.0049 16.4 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AJW71334.1 - 0.024 13.4 0.0 0.049 12.4 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase PAPS_reduct PF01507.19 AJW71334.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.21 AJW71334.1 - 0.2 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase eIF-5a PF01287.20 AJW71335.1 - 2.5e-07 30.7 2.7 3.5e-07 30.2 2.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 AJW71335.1 - 6e-06 26.2 0.1 0.053 13.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor P (EF-P) KOW-like domain F5_F8_type_C PF00754.25 AJW71336.1 - 0.043 13.9 0.0 0.093 12.9 0.0 1.6 2 0 0 2 2 2 0 F5/8 type C domain CSD PF00313.22 AJW71337.1 - 3e-21 75.0 3.5 3.7e-21 74.7 3.5 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AJW71337.1 - 1.8e-06 27.5 1.0 2e-06 27.4 1.0 1.1 1 0 0 1 1 1 1 Ribonuclease B OB domain MazE_antitoxin PF04014.18 AJW71337.1 - 0.13 12.2 1.1 0.32 11.0 1.1 1.8 1 1 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin eIF-1a PF01176.19 AJW71338.1 - 1.1e-17 63.6 1.1 1.5e-17 63.2 1.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.19 AJW71338.1 - 0.091 12.6 0.2 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain CxxCxxCC PF03692.15 AJW71339.1 - 2.1e-10 41.2 1.1 4.9e-10 40.0 1.0 1.7 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain HTH_AsnC-type PF13404.6 AJW71340.1 - 1.3e-09 37.7 0.6 1.3e-08 34.6 0.6 2.4 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJW71340.1 - 5e-08 32.4 7.4 0.0001 21.8 0.1 2.8 4 0 0 4 4 4 2 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 AJW71340.1 - 2.3e-07 30.7 0.5 5.1e-07 29.5 0.3 1.7 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_11 PF08279.12 AJW71340.1 - 3.6e-06 26.8 0.6 1.5e-05 24.8 0.6 2.0 1 1 0 1 1 1 1 HTH domain HTH_Tnp_Tc3_2 PF01498.18 AJW71340.1 - 2e-05 24.7 0.4 5.3e-05 23.4 0.1 1.8 2 0 0 2 2 1 1 Transposase Penicillinase_R PF03965.16 AJW71340.1 - 0.0002 21.7 0.3 0.00051 20.4 0.0 1.9 2 1 0 2 2 2 1 Penicillinase repressor HTH_20 PF12840.7 AJW71340.1 - 0.00045 20.2 0.0 0.00068 19.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 AJW71340.1 - 0.0022 17.7 0.1 0.0065 16.2 0.1 1.8 1 1 0 1 1 1 1 DeoR-like helix-turn-helix domain DUF3658 PF12395.8 AJW71340.1 - 0.0034 17.3 0.1 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function HTH_32 PF13565.6 AJW71340.1 - 0.0098 16.5 0.0 0.031 14.9 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain Myb_DNA-bind_4 PF13837.6 AJW71340.1 - 0.017 15.5 0.5 0.043 14.2 0.1 1.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain FUR PF01475.19 AJW71340.1 - 0.021 14.9 0.3 0.041 14.0 0.0 1.5 2 0 0 2 2 2 0 Ferric uptake regulator family DUF3783 PF12646.7 AJW71340.1 - 0.049 13.6 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Nuc_N PF14448.6 AJW71340.1 - 0.052 13.4 0.7 0.087 12.7 0.2 1.6 2 0 0 2 2 2 0 Nuclease N terminal Type2_restr_D3 PF16902.5 AJW71340.1 - 0.061 13.2 0.7 0.56 10.2 0.1 2.3 1 1 1 2 2 2 0 Type-2 restriction enzyme D3 domain Arg_repressor PF01316.21 AJW71340.1 - 0.062 13.1 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Sigma70_r4_2 PF08281.12 AJW71340.1 - 0.077 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 GGDEF_2 PF17853.1 AJW71340.1 - 0.089 13.1 0.0 0.21 11.8 0.0 1.5 2 0 0 2 2 2 0 GGDEF-like domain DUF2120 PF09893.9 AJW71340.1 - 1 9.4 4.9 14 5.8 0.0 2.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Response_reg PF00072.24 AJW71341.1 - 1.3e-18 67.2 0.2 2e-18 66.6 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain TPR_2 PF07719.17 AJW71341.1 - 0.00018 21.4 0.3 0.0024 17.8 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AJW71341.1 - 0.0007 19.8 2.4 0.52 10.6 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AJW71341.1 - 0.00076 19.2 0.6 0.0041 16.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AJW71341.1 - 0.031 14.5 3.0 0.11 12.7 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AJW71341.1 - 0.085 13.2 0.1 4.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 AJW71341.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 AJW71341.1 - 0.14 12.8 0.6 1.4 9.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat IL3 PF02059.15 AJW71341.1 - 0.15 12.2 1.4 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 Interleukin-3 ADH_N PF08240.12 AJW71342.1 - 1.4e-31 108.6 0.3 2.2e-31 107.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AJW71342.1 - 9.9e-29 100.0 0.4 1.5e-28 99.4 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AJW71342.1 - 1.5e-10 42.2 0.0 2.9e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AJW71342.1 - 4.1e-09 36.2 0.1 6.7e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus PglD_N PF17836.1 AJW71342.1 - 0.00029 21.4 0.6 0.00065 20.3 0.6 1.7 1 0 0 1 1 1 1 PglD N-terminal domain AlaDh_PNT_C PF01262.21 AJW71342.1 - 0.0012 18.2 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AJW71342.1 - 0.015 15.5 0.2 0.044 14.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain SDH_sah PF01972.16 AJW71342.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase UDPG_MGDP_dh_N PF03721.14 AJW71342.1 - 0.11 12.1 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SMC_ScpA PF02616.14 AJW71343.1 - 5.2e-07 29.8 1.7 0.0027 17.6 0.1 2.1 2 0 0 2 2 2 2 Segregation and condensation protein ScpA SMC_ScpB PF04079.16 AJW71344.1 - 8.2e-35 119.8 0.4 9.9e-35 119.5 0.4 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HHH_3 PF12836.7 AJW71344.1 - 0.029 14.6 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ribosomal_S8e PF01201.22 AJW71345.1 - 1.3e-22 80.4 3.3 1.5e-22 80.2 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SRP19 PF01922.17 AJW71346.1 - 1.4e-12 48.4 0.0 1.9e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein Gar1 PF04410.14 AJW71347.1 - 2.7e-08 33.7 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region TFIIB PF00382.19 AJW71348.1 - 2e-24 85.4 2.3 2.9e-11 43.3 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW71348.1 - 1.7e-11 43.4 2.4 1.7e-11 43.4 2.4 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding RPA_interact_C PF14768.6 AJW71348.1 - 0.0021 18.6 1.3 0.21 12.1 1.3 3.0 1 1 0 1 1 1 1 Replication protein A interacting C-terminal Auto_anti-p27 PF06677.12 AJW71348.1 - 0.026 14.7 1.1 0.026 14.7 1.1 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cys_knot PF00007.22 AJW71348.1 - 0.071 13.4 0.9 0.071 13.4 0.9 2.2 2 0 0 2 2 2 0 Cystine-knot domain OrfB_Zn_ribbon PF07282.11 AJW71348.1 - 0.075 13.0 1.6 0.15 12.0 0.4 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 AJW71348.1 - 0.12 12.1 0.4 0.12 12.1 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 AJW71348.1 - 0.45 10.6 4.0 0.28 11.2 0.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon Spt4 PF06093.13 AJW71348.1 - 2.6 8.2 8.6 1.9 8.6 1.1 3.3 3 2 0 3 3 3 0 Spt4/RpoE2 zinc finger zf-ribbon_3 PF13248.6 AJW71348.1 - 8.7 5.9 9.5 1.5 8.3 3.4 2.7 2 1 0 2 2 2 0 zinc-ribbon domain ABC_tran PF00005.27 AJW71349.1 - 3.6e-20 72.9 0.0 5.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AJW71349.1 - 8e-11 41.8 0.4 5.8e-06 25.9 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AJW71349.1 - 1.2e-09 38.4 0.1 8.1e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AJW71349.1 - 0.00054 19.7 0.5 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AJW71349.1 - 0.002 18.3 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AJW71349.1 - 0.0021 17.7 0.1 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AJW71349.1 - 0.0071 16.8 0.3 0.13 12.7 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AJW71349.1 - 0.0086 16.5 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 AJW71349.1 - 0.012 15.3 0.1 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AJW71349.1 - 0.016 15.5 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AJW71349.1 - 0.024 14.3 0.0 0.4 10.3 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AJW71349.1 - 0.027 15.0 1.1 0.058 13.9 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AJW71349.1 - 0.037 13.7 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AJW71349.1 - 0.045 14.3 0.1 0.45 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 AJW71349.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AJW71349.1 - 0.056 12.1 1.3 1.9 7.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 AJW71349.1 - 0.069 13.4 0.1 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AJW71349.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 AJW71349.1 - 0.09 12.7 1.3 0.4 10.6 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Acetyltransf_18 PF18014.1 AJW71349.1 - 0.1 12.4 0.0 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_17 PF13207.6 AJW71349.1 - 0.11 12.9 0.1 0.64 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.21 AJW71349.1 - 0.15 12.0 0.1 4.2 7.4 0.0 2.1 2 0 0 2 2 2 0 MutS domain V RNA_helicase PF00910.22 AJW71349.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.7 2 0 0 2 2 1 0 RNA helicase DUF167 PF02594.16 AJW71350.1 - 9.8e-14 51.2 1.0 1.1e-13 51.1 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 HEPN_RiboL-PSP PF18735.1 AJW71350.1 - 0.014 15.3 4.8 0.015 15.2 4.8 1.0 1 0 0 1 1 1 0 RiboL-PSP-HEPN MMR_HSR1_Xtn PF16897.5 AJW71350.1 - 0.022 14.8 0.3 0.026 14.5 0.3 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Chlor_dismutase PF06778.12 AJW71351.1 - 3.2e-56 190.0 0.1 3.9e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Chlorite dismutase Pterin_4a PF01329.19 AJW71351.1 - 0.083 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase AsnC_trans_reg PF01037.21 AJW71351.1 - 0.12 12.3 1.6 17 5.5 0.4 2.5 2 1 0 2 2 2 0 Lrp/AsnC ligand binding domain Aldo_ket_red PF00248.21 AJW71352.1 - 3.1e-50 171.1 0.1 3.5e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FB_lectin PF07367.11 AJW71353.1 - 0.06 13.3 0.3 0.095 12.6 0.2 1.3 1 1 0 1 1 1 0 Fungal fruit body lectin zf-B_box PF00643.24 AJW71353.1 - 0.066 13.4 2.4 0.1 12.8 2.4 1.3 1 0 0 1 1 1 0 B-box zinc finger AsnC_trans_reg2 PF17805.1 AJW71354.1 - 6.8e-54 180.0 0.0 1.6e-30 105.0 0.0 2.5 2 0 0 2 2 2 2 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AJW71354.1 - 0.00045 20.0 0.0 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AJW71354.1 - 0.013 15.0 0.2 0.23 11.0 0.2 2.4 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF262 PF03235.14 AJW71354.1 - 0.049 13.8 0.7 0.071 13.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF262 AsnC_trans_reg PF01037.21 AJW71354.1 - 0.051 13.6 0.0 9 6.3 0.0 3.1 2 1 0 2 2 2 0 Lrp/AsnC ligand binding domain Muted PF14942.6 AJW71354.1 - 0.059 13.7 2.6 0.14 12.5 0.5 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein NAD_binding_7 PF13241.6 AJW71355.1 - 3.9e-20 72.2 1.7 1.7e-19 70.1 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 AJW71355.1 - 5.8e-05 23.2 0.7 5.8e-05 23.2 0.7 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sirohm_synth_M PF14824.6 AJW71355.1 - 0.00023 20.5 0.1 0.00058 19.2 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central F420_oxidored PF03807.17 AJW71355.1 - 0.0049 17.4 1.4 0.016 15.8 0.3 2.4 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent LSDAT_prok PF18171.1 AJW71355.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote CysG_dimeriser PF10414.9 AJW71355.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region THF_DHG_CYH_C PF02882.19 AJW71355.1 - 0.04 13.2 0.1 0.072 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RibD_C PF01872.17 AJW71355.1 - 0.079 12.8 0.2 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 RibD C-terminal domain GlutR_N PF05201.15 AJW71356.1 - 2.6e-37 127.8 0.3 6.1e-37 126.6 0.3 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AJW71356.1 - 9e-28 97.1 0.4 2.1e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AJW71356.1 - 1.9e-18 66.7 1.8 5.6e-18 65.2 1.8 1.9 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain FAM25 PF15825.5 AJW71356.1 - 0.026 14.9 0.3 0.026 14.9 0.3 2.2 2 0 0 2 2 2 0 FAM25 family DUF1664 PF07889.12 AJW71356.1 - 8.4 6.4 12.5 1.7 8.7 2.2 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) ALAD PF00490.21 AJW71357.1 - 1.4e-133 444.9 1.9 1.6e-133 444.8 1.9 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase JmjN PF02375.17 AJW71358.1 - 0.00061 19.7 8.5 0.05 13.6 3.6 2.3 1 1 1 2 2 2 2 jmjN domain DUF1896 PF08989.10 AJW71358.1 - 0.017 15.2 0.7 0.021 14.9 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1896) Phage_int_SAM_4 PF13495.6 AJW71358.1 - 0.087 13.3 0.4 0.12 12.9 0.4 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SNARE_assoc PF09335.11 AJW71359.1 - 0.013 16.0 6.4 0.013 16.0 6.4 1.6 2 0 0 2 2 2 0 SNARE associated Golgi protein REPA_OB_2 PF16900.5 AJW71360.1 - 0.047 13.6 0.6 0.055 13.4 0.6 1.2 1 0 0 1 1 1 0 Replication protein A OB domain DUF3127 PF11325.8 AJW71360.1 - 0.078 13.2 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) DUF3671 PF12420.8 AJW71361.1 - 0.071 13.2 1.8 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2371 PF10177.9 AJW71361.1 - 0.16 12.1 1.4 1.1 9.4 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) HC2 PF07382.11 AJW71363.1 - 1.2e-13 51.6 123.1 1.2e-13 51.6 123.1 1.6 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF4404 PF14357.6 AJW71363.1 - 0.058 14.0 3.1 0.16 12.6 3.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) MscS_porin PF12795.7 AJW71364.1 - 1.5e-06 28.0 22.9 1.9e-06 27.6 22.9 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Spc7 PF08317.11 AJW71364.1 - 0.00019 20.4 18.8 0.00019 20.4 18.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein AAA_13 PF13166.6 AJW71364.1 - 0.00032 19.5 21.1 0.00048 18.9 21.1 1.2 1 0 0 1 1 1 1 AAA domain CorA PF01544.18 AJW71364.1 - 0.002 17.5 9.3 0.0027 17.1 9.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein T3SSipB PF16535.5 AJW71364.1 - 0.0032 18.0 10.2 0.0032 18.0 10.2 2.1 1 1 1 2 2 2 1 Type III cell invasion protein SipB FliJ PF02050.16 AJW71364.1 - 0.01 16.1 23.7 0.017 15.4 1.1 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein SOAR PF16533.5 AJW71364.1 - 0.015 15.3 6.2 0.015 15.3 6.2 2.5 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF745 PF05335.13 AJW71364.1 - 0.021 14.5 21.8 0.8 9.4 21.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF745) MCPsignal PF00015.21 AJW71364.1 - 0.021 14.6 16.5 0.071 12.9 6.1 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WEMBL PF05701.11 AJW71364.1 - 0.023 13.4 25.6 0.041 12.6 17.1 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.12 AJW71364.1 - 0.065 13.3 5.3 0.067 13.2 3.9 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 AJW71364.1 - 0.1 12.2 15.4 0.15 11.6 15.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HrpB7 PF09486.10 AJW71364.1 - 0.13 12.7 18.5 0.58 10.5 0.5 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 AJW71364.1 - 0.14 12.3 19.1 0.17 12.0 5.4 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C4H2 PF10146.9 AJW71364.1 - 0.17 12.1 23.6 0.063 13.6 12.2 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein ATG16 PF08614.11 AJW71364.1 - 0.21 11.8 27.0 4.7 7.4 7.7 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MIP-T3_C PF17749.1 AJW71364.1 - 0.26 11.2 19.2 0.37 10.8 19.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region TolA_bind_tri PF16331.5 AJW71364.1 - 0.3 11.2 17.0 0.68 10.1 0.6 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF4407 PF14362.6 AJW71364.1 - 0.4 10.0 17.5 0.56 9.5 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HR1 PF02185.16 AJW71364.1 - 0.5 10.5 24.7 10 6.4 9.8 3.7 3 1 0 3 3 2 0 Hr1 repeat NPV_P10 PF05531.12 AJW71364.1 - 0.56 10.7 12.7 0.48 10.9 2.1 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein ERM PF00769.19 AJW71364.1 - 0.58 9.9 31.4 0.32 10.8 19.9 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DASH_Duo1 PF08651.10 AJW71364.1 - 0.62 9.9 12.1 2.2 8.1 0.3 3.3 2 1 2 4 4 4 0 DASH complex subunit Duo1 Peptidase_S64 PF08192.11 AJW71364.1 - 0.75 8.2 13.2 0.88 8.0 13.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2203 PF09969.9 AJW71364.1 - 1.1 9.9 18.9 3.8 8.2 5.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 AJW71364.1 - 1.4 8.9 19.0 2 8.5 6.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 AJW71364.1 - 1.6 9.1 31.1 3.3 8.1 15.9 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4460 PF14687.6 AJW71364.1 - 1.6 8.8 9.8 0.26 11.3 1.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4460) Allexi_40kDa PF05549.11 AJW71364.1 - 1.6 8.1 16.2 1.1 8.7 4.5 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF883 PF05957.13 AJW71364.1 - 1.9 9.1 19.2 1.4 9.6 2.3 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 AJW71364.1 - 2.4 8.5 9.7 5.5 7.3 0.3 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 AJW71364.1 - 3.2 8.2 26.0 6.8 7.1 2.3 2.1 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 AJW71364.1 - 3.7 7.7 22.8 7.4 6.8 2.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 AJW71364.1 - 5.6 6.0 26.2 9.9 5.1 26.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAP206 PF12018.8 AJW71364.1 - 5.8 6.3 13.6 2.6 7.5 7.8 2.1 2 0 0 2 2 2 0 Domain of unknown function IMD PF08397.11 AJW71364.1 - 5.9 6.2 19.5 1.3 8.3 11.5 2.1 1 1 1 2 2 2 0 IRSp53/MIM homology domain APG6_N PF17675.1 AJW71364.1 - 6 7.4 30.8 10 6.6 11.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 AJW71364.1 - 7.4 6.7 30.8 34 4.6 10.8 2.6 1 1 1 2 2 2 0 Tropomyosin like TMPIT PF07851.13 AJW71364.1 - 7.4 5.7 21.6 1 8.5 6.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein PAP2 PF01569.21 AJW71366.1 - 1.3e-21 76.8 0.8 1.3e-21 76.8 0.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AJW71366.1 - 6.9e-08 32.4 7.5 6.9e-08 32.4 7.5 2.3 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 AJW71366.1 - 4.7e-05 23.8 0.2 4.7e-05 23.8 0.2 2.8 3 1 0 3 3 3 1 PAP2 superfamily C-terminal PGK PF00162.19 AJW71367.1 - 3.8e-97 325.6 0.2 4.4e-97 325.4 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF1033 PF06279.11 AJW71368.1 - 0.0054 16.9 0.0 0.0066 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1033) NifU_N PF01592.16 AJW71369.1 - 2.3e-30 105.3 0.1 2.7e-30 105.1 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain SufE PF02657.15 AJW71369.1 - 0.0082 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain Aminotran_5 PF00266.19 AJW71370.1 - 3e-148 493.7 1.1 3.4e-148 493.5 1.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AJW71370.1 - 3.4e-06 26.5 0.1 5.5e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJW71370.1 - 0.00079 18.1 0.3 0.0047 15.5 0.1 2.0 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Rieske PF00355.26 AJW71371.1 - 6.9e-16 58.0 0.0 8.1e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJW71371.1 - 6.5e-12 45.3 0.0 7.4e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0051 PF01458.17 AJW71372.1 - 6.5e-62 209.1 1.1 9.5e-62 208.5 1.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF2152 PF10222.9 AJW71372.1 - 0.0059 15.0 0.0 0.01 14.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) FadA PF09403.10 AJW71372.1 - 0.044 14.3 0.5 0.37 11.3 0.0 2.5 2 0 0 2 2 2 0 Adhesion protein FadA DUF957 PF06117.11 AJW71372.1 - 0.19 11.3 1.1 20 4.8 0.4 2.9 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) UPF0051 PF01458.17 AJW71373.1 - 3.8e-73 245.8 0.1 5.1e-73 245.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF1307 PF06998.11 AJW71373.1 - 0.11 12.5 2.0 0.2 11.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) HEM4 PF02602.15 AJW71374.1 - 3.1e-44 151.1 0.0 3.5e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TP_methylase PF00590.20 AJW71375.1 - 3.5e-50 170.9 0.1 4e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA_int_endo PF01974.17 AJW71375.1 - 0.11 12.6 1.1 0.26 11.4 0.1 2.1 2 1 1 3 3 3 0 tRNA intron endonuclease, catalytic C-terminal domain Aminotran_3 PF00202.21 AJW71376.1 - 1.7e-74 250.9 0.0 2e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AJW71376.1 - 7.1e-06 25.4 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1_N PF03709.15 AJW71376.1 - 0.062 13.6 0.0 0.43 10.9 0.0 2.3 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain zf-ribbon_3 PF13248.6 AJW71378.1 - 0.0015 17.9 5.9 0.018 14.5 0.4 2.4 3 0 0 3 3 3 2 zinc-ribbon domain HscB_4_cys PF18256.1 AJW71378.1 - 0.095 12.5 6.2 0.99 9.3 6.2 2.2 1 1 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif eIF-5_eIF-2B PF01873.17 AJW71378.1 - 0.47 10.3 4.3 0.57 10.1 4.3 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 zinc_ribbon_2 PF13240.6 AJW71378.1 - 1.8 8.4 12.1 0.96 9.2 0.4 3.0 3 0 0 3 3 3 0 zinc-ribbon domain MIP PF00230.20 AJW71380.1 - 9.7e-37 126.9 19.9 1.2e-36 126.5 19.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein LMWPc PF01451.21 AJW71381.1 - 4.8e-12 46.5 0.2 2.3e-11 44.3 0.2 1.8 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase HTH_5 PF01022.20 AJW71382.1 - 2e-16 59.6 0.2 3.7e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AJW71382.1 - 5.2e-08 32.3 0.3 2.1e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AJW71382.1 - 7.1e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 AJW71382.1 - 0.00074 19.4 0.3 0.0032 17.4 0.0 1.9 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AJW71382.1 - 0.0061 16.4 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 AJW71382.1 - 0.0064 16.7 0.0 0.0091 16.2 0.0 1.3 1 1 0 1 1 1 1 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 AJW71382.1 - 0.0085 15.9 0.3 0.011 15.6 0.3 1.1 1 0 0 1 1 1 1 TFIIE alpha subunit PH_16 PF17838.1 AJW71382.1 - 0.021 14.7 0.2 0.026 14.3 0.2 1.1 1 0 0 1 1 1 0 PH domain MarR_2 PF12802.7 AJW71382.1 - 0.022 14.6 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 MarR family Penicillinase_R PF03965.16 AJW71382.1 - 0.036 14.4 0.2 0.048 14.0 0.2 1.2 1 0 0 1 1 1 0 Penicillinase repressor HTH_IclR PF09339.10 AJW71382.1 - 0.04 13.7 0.0 0.098 12.5 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Cdc6_C PF09079.11 AJW71382.1 - 0.04 13.9 0.2 0.051 13.5 0.2 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Rrf2 PF02082.20 AJW71382.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 Transcriptional regulator DUF5343 PF17278.2 AJW71382.1 - 0.15 12.2 0.2 1.3 9.1 0.1 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5343) P-II PF00543.22 AJW71383.1 - 6.6e-05 23.4 0.3 8.5e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF190 PF02641.15 AJW71383.1 - 0.015 15.6 0.2 0.026 14.9 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, COG1993 DUF3240 PF11582.8 AJW71383.1 - 0.021 14.9 0.2 0.049 13.8 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) Rad1 PF02144.16 AJW71383.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 Sbt_1 PF05982.12 AJW71384.1 - 1.3e-103 346.5 22.4 1.5e-103 346.3 22.4 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily DUF1772 PF08592.11 AJW71384.1 - 3.7 7.8 9.8 1.3 9.3 3.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF866 PF05907.13 AJW71385.1 - 0.0029 17.5 2.8 0.12 12.2 0.1 2.8 3 0 0 3 3 3 2 Eukaryotic protein of unknown function (DUF866) NHL PF01436.21 AJW71386.1 - 4.4e-35 118.0 1.0 6.3e-09 35.4 0.0 6.7 6 0 0 6 6 6 6 NHL repeat HemolysinCabind PF00353.19 AJW71386.1 - 2.4e-17 62.6 44.3 4.3e-09 36.2 18.2 3.6 1 1 2 3 3 3 3 RTX calcium-binding nonapeptide repeat (4 copies) SGL PF08450.12 AJW71386.1 - 1.2e-12 48.0 3.8 2e-05 24.3 0.1 4.1 3 2 1 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 AJW71386.1 - 1.9e-10 40.4 7.4 1.4e-05 24.5 1.2 3.1 2 1 1 3 3 3 2 6-bladed beta-propeller SBBP PF06739.11 AJW71386.1 - 3.9e-07 29.9 18.1 0.0012 18.8 0.6 5.8 6 0 0 6 6 6 3 Beta-propeller repeat TolB_like PF15869.5 AJW71386.1 - 1.6e-06 27.6 0.2 0.021 14.1 0.0 2.3 1 1 1 2 2 2 2 TolB-like 6-blade propeller-like DUF4988 PF16378.5 AJW71386.1 - 0.00016 21.4 0.1 0.52 10.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function Phytase-like PF13449.6 AJW71386.1 - 0.0002 21.4 0.4 3 7.7 0.0 3.9 2 2 1 3 3 3 2 Esterase-like activity of phytase HYR PF02494.16 AJW71386.1 - 0.00067 19.9 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 HYR domain PQQ_3 PF13570.6 AJW71386.1 - 0.0043 17.5 3.0 2.6 8.7 0.0 5.0 5 0 0 5 5 5 1 PQQ-like domain LVIVD PF08309.11 AJW71386.1 - 0.0075 15.6 0.1 0.0075 15.6 0.1 3.9 4 0 0 4 4 4 1 LVIVD repeat Ldl_recept_b PF00058.17 AJW71386.1 - 0.023 15.2 0.0 13 6.3 0.0 4.0 3 1 0 3 3 3 0 Low-density lipoprotein receptor repeat class B ABC2_membrane PF01061.24 AJW71387.1 - 1.6e-33 115.9 17.3 1.6e-33 115.9 17.3 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AJW71387.1 - 3.1e-13 49.6 28.3 3.7e-13 49.3 28.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AJW71387.1 - 0.00018 20.9 26.4 0.0018 17.6 26.4 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 AJW71388.1 - 9.9e-31 107.1 0.0 2.2e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJW71388.1 - 1.9e-09 37.7 2.1 1.4e-05 25.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AJW71388.1 - 2.4e-06 28.2 1.6 2.6e-06 28.0 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 AJW71388.1 - 9.5e-05 22.3 0.5 0.082 12.6 0.2 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AJW71388.1 - 0.0054 16.5 0.2 0.013 15.3 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AJW71388.1 - 0.0096 15.4 0.3 0.032 13.6 0.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AJW71388.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AJW71388.1 - 0.032 13.9 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.6 AJW71388.1 - 0.054 14.0 7.6 0.053 14.0 5.2 2.2 2 1 0 2 2 2 0 AAA domain YopD PF05844.12 AJW71388.1 - 0.08 11.9 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 YopD protein PRC PF05239.16 AJW71389.1 - 8.6e-11 41.8 1.0 0.00029 20.9 0.1 2.2 2 0 0 2 2 2 2 PRC-barrel domain DUF2171 PF09939.9 AJW71389.1 - 2.4e-05 24.5 0.9 0.015 15.6 0.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2171) MlaD PF02470.20 AJW71389.1 - 0.0017 18.6 0.1 0.52 10.6 0.0 2.2 2 0 0 2 2 2 2 MlaD protein GTP_EFTU_D4 PF14578.6 AJW71389.1 - 0.0043 16.9 0.2 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu domain 4 F420H2_quin_red PF04075.14 AJW71390.1 - 7.1e-09 35.9 0.0 8.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 AJW71390.1 - 0.0052 16.9 0.0 0.0058 16.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) Putative_PNPOx PF01243.20 AJW71390.1 - 0.053 13.7 0.1 0.24 11.6 0.1 1.9 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase HTH_5 PF01022.20 AJW71391.1 - 3.1e-08 33.3 0.3 7.1e-08 32.2 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AJW71391.1 - 5.4e-07 29.1 0.2 1.1e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AJW71391.1 - 3.1e-06 27.1 0.0 5.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIE_alpha PF02002.17 AJW71391.1 - 7.9e-05 22.5 1.0 0.00017 21.4 0.3 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_11 PF08279.12 AJW71391.1 - 0.00014 21.7 2.8 0.001 19.0 1.2 2.5 2 0 0 2 2 2 1 HTH domain TrmB PF01978.19 AJW71391.1 - 0.00016 21.5 0.1 0.00035 20.4 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 AJW71391.1 - 0.0033 16.9 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 AJW71391.1 - 0.0076 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_9 PF08221.11 AJW71391.1 - 0.018 15.1 0.1 0.043 13.9 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_34 PF13601.6 AJW71391.1 - 0.025 14.7 1.1 0.06 13.5 1.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Sigma70_r4_2 PF08281.12 AJW71391.1 - 0.033 13.8 0.1 0.084 12.6 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_45 PF14947.6 AJW71391.1 - 0.036 14.1 1.4 0.071 13.1 1.4 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_40 PF14493.6 AJW71391.1 - 0.065 13.7 1.0 0.11 12.9 0.3 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 AJW71391.1 - 0.15 12.4 0.9 0.39 11.1 0.2 2.0 2 0 0 2 2 2 0 Transcriptional regulator Beta_propel PF09826.9 AJW71392.1 - 4.7e-151 504.1 16.3 5.7e-151 503.9 16.3 1.1 1 0 0 1 1 1 1 Beta propeller domain LVIVD PF08309.11 AJW71392.1 - 0.09 12.1 3.6 8 5.9 0.1 3.4 3 0 0 3 3 3 0 LVIVD repeat Rod_C PF10493.9 AJW71392.1 - 0.13 10.7 2.2 0.19 10.1 2.2 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region DUF241 PF03087.14 AJW71392.1 - 0.3 10.9 3.4 0.56 10.0 3.4 1.3 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Glyco_transf_90 PF05686.12 AJW71393.1 - 0.079 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 TPR_1 PF00515.28 AJW71395.1 - 1.6e-12 46.7 2.0 4.4e-05 23.1 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AJW71395.1 - 1.2e-11 43.8 0.4 0.002 18.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AJW71395.1 - 3e-10 39.5 0.2 0.0008 19.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AJW71395.1 - 2.5e-09 37.5 0.4 1.1e-06 29.1 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AJW71395.1 - 2.6e-08 34.0 0.0 0.0058 17.3 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJW71395.1 - 7.6e-07 28.7 0.1 0.7 10.1 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AJW71395.1 - 5.3e-06 26.6 0.1 0.00085 19.5 0.2 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 AJW71395.1 - 1.1e-05 25.7 0.0 0.022 15.0 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 AJW71395.1 - 0.00045 19.5 0.0 0.12 11.6 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 AJW71395.1 - 0.0014 18.8 0.4 0.87 10.1 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AJW71395.1 - 0.0031 17.6 1.5 0.044 13.9 0.2 2.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 AJW71395.1 - 0.0077 16.9 0.0 0.86 10.3 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AJW71395.1 - 0.021 14.5 0.8 26 4.6 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 AJW71395.1 - 0.039 14.1 0.0 0.83 9.8 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat SSrecog PF03531.14 AJW71395.1 - 0.087 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) Metallothio PF00131.20 AJW71398.1 - 0.0059 16.7 14.6 0.0059 16.7 14.6 1.9 1 1 1 2 2 2 1 Metallothionein tRNA_int_endo PF01974.17 AJW71401.1 - 8.6e-21 73.8 0.2 3.5e-20 71.9 0.1 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 AJW71401.1 - 1.3e-11 44.0 2.7 3.2e-10 39.5 0.4 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Imm58 PF15581.6 AJW71401.1 - 0.12 12.5 0.3 0.53 10.4 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 58 Ribosomal_L16 PF00252.18 AJW71402.1 - 8.5e-26 90.5 1.1 1.1e-25 90.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ssDNA-exonuc_C PF10141.9 AJW71403.1 - 0.011 15.4 0.4 0.013 15.2 0.4 1.3 1 1 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain RecG_N PF17190.4 AJW71403.1 - 0.046 14.4 3.3 2.4 9.0 0.3 2.1 1 1 1 2 2 2 0 RecG N-terminal helical domain JmjN PF02375.17 AJW71403.1 - 0.048 13.6 0.2 0.096 12.7 0.2 1.5 1 0 0 1 1 1 0 jmjN domain SapB_1 PF05184.15 AJW71403.1 - 0.17 11.9 1.4 1.4 9.0 0.7 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 Na_H_Exchanger PF00999.21 AJW71405.1 - 4.6e-50 170.5 57.0 5.8e-50 170.2 57.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YabQ PF09578.10 AJW71405.1 - 0.00022 21.4 0.3 0.00022 21.4 0.3 5.3 5 1 1 6 6 6 1 Spore cortex protein YabQ (Spore_YabQ) Sec34 PF04136.15 AJW71406.1 - 0.0022 17.9 30.6 0.12 12.3 2.0 5.1 3 1 2 5 5 5 2 Sec34-like family DUF948 PF06103.11 AJW71406.1 - 0.0022 18.2 24.5 0.18 12.1 1.2 5.6 1 1 4 5 5 5 1 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 AJW71406.1 - 0.0024 17.9 2.6 0.0024 17.9 2.6 5.0 1 1 4 5 5 5 1 Designed helical repeat protein 10 domain CENP-Q PF13094.6 AJW71406.1 - 0.0025 18.0 8.0 0.0025 18.0 8.0 3.9 2 1 2 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.12 AJW71406.1 - 0.0052 16.8 38.2 0.038 14.0 1.4 5.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Laminin_II PF06009.12 AJW71406.1 - 0.044 13.8 38.8 0.079 13.0 4.4 4.5 1 1 3 5 5 5 0 Laminin Domain II RPW8 PF05659.11 AJW71406.1 - 0.057 13.1 0.4 0.057 13.1 0.4 5.5 1 1 3 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NPV_P10 PF05531.12 AJW71406.1 - 0.089 13.3 0.5 0.089 13.3 0.5 7.0 2 1 6 8 8 7 0 Nucleopolyhedrovirus P10 protein YqjK PF13997.6 AJW71406.1 - 0.13 12.5 0.0 0.71 10.2 0.0 2.3 1 0 0 1 1 1 0 YqjK-like protein KxDL PF10241.9 AJW71406.1 - 0.16 12.3 29.6 0.47 10.8 0.3 6.9 4 2 2 6 6 6 0 Uncharacterized conserved protein ATG16 PF08614.11 AJW71406.1 - 1.3 9.2 31.7 0.13 12.5 5.9 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) SpecificRecomb PF10136.9 AJW71406.1 - 1.4 7.1 9.6 0.28 9.5 5.4 1.8 2 0 0 2 2 2 0 Site-specific recombinase Syntaxin-6_N PF09177.11 AJW71406.1 - 1.7 9.3 22.6 18 6.0 6.7 5.1 1 1 2 4 4 4 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 AJW71406.1 - 1.7 8.4 39.3 10 5.9 0.6 4.4 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH Allexi_40kDa PF05549.11 AJW71406.1 - 2.2 7.7 32.0 1.8 8.0 11.2 4.5 1 1 5 6 6 6 0 Allexivirus 40kDa protein BLOC1_2 PF10046.9 AJW71406.1 - 6.5 7.1 42.4 3.7 7.9 5.6 6.8 1 1 6 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cauli_AT PF03233.13 AJW71406.1 - 7 6.5 41.9 0.098 12.6 1.6 5.0 1 1 4 6 6 6 0 Aphid transmission protein SesA PF17107.5 AJW71406.1 - 7.4 6.8 25.7 5.2 7.3 7.8 4.8 1 1 2 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Glyco_tranf_2_3 PF13641.6 AJW71407.1 - 5.2e-24 85.4 0.0 8e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AJW71407.1 - 1.8e-20 73.7 0.3 3.8e-20 72.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 AJW71407.1 - 2.1e-18 66.7 0.1 3.7e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AJW71407.1 - 1.5e-12 47.4 0.1 2.4e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 AJW71407.1 - 0.019 15.4 0.3 0.082 13.4 0.4 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Fer4 PF00037.27 AJW71409.1 - 5.7e-08 32.3 16.0 0.00016 21.3 3.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AJW71409.1 - 1.6e-05 25.0 3.7 2.9e-05 24.1 3.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJW71409.1 - 2.3e-05 24.9 5.1 0.0002 21.9 6.1 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJW71409.1 - 5.2e-05 23.3 5.8 0.00013 22.0 5.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJW71409.1 - 0.00032 20.8 3.8 0.00053 20.1 3.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain ETF_QO PF05187.13 AJW71409.1 - 0.00084 19.4 0.5 0.0017 18.4 0.5 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_6 PF12837.7 AJW71409.1 - 0.0036 17.3 13.1 0.005 16.9 1.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Tenui_PVC2 PF06656.11 AJW71409.1 - 0.0037 15.2 0.2 0.0052 14.8 0.2 1.1 1 0 0 1 1 1 1 Tenuivirus PVC2 protein Fer4_17 PF13534.6 AJW71409.1 - 0.021 15.3 1.7 9 6.9 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Me-amine-dh_L PF02975.14 AJW71409.1 - 0.14 12.6 2.6 0.24 11.9 2.6 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Fer4_16 PF13484.6 AJW71409.1 - 0.27 12.2 8.5 2.8 8.9 2.6 2.7 1 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AJW71409.1 - 0.28 11.7 5.6 6.2 7.3 6.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJW71409.1 - 1.1 9.5 3.5 6.4 7.0 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AJW71409.1 - 2.5 8.4 9.4 4.9 7.5 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AJW71409.1 - 2.8 9.1 14.2 11 7.2 5.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 AJW71409.1 - 3 8.4 9.5 0.57 10.8 0.6 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Rhodanese PF00581.20 AJW71411.1 - 3.9e-35 120.6 0.1 3.7e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NAD_kinase PF01513.21 AJW71412.1 - 4.8e-32 111.3 1.5 7e-32 110.8 1.5 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AJW71412.1 - 4.5e-05 23.1 0.1 7.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CoA_binding_2 PF13380.6 AJW71412.1 - 0.0017 18.9 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain PIN_6 PF17146.4 AJW71413.1 - 4.4e-18 65.6 0.1 6.4e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 PIN domain of ribonuclease PIN_5 PF08745.11 AJW71413.1 - 1e-06 28.3 0.0 0.00037 20.0 0.0 2.1 2 0 0 2 2 2 2 PINc domain ribonuclease PIN PF01850.21 AJW71413.1 - 1.6e-06 28.6 0.3 2.5e-06 28.0 0.3 1.3 1 1 0 1 1 1 1 PIN domain DNA_ligase_ZBD PF03119.16 AJW71413.1 - 0.033 14.2 0.9 0.27 11.3 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 AJW71413.1 - 0.037 14.0 1.7 0.069 13.2 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 AJW71413.1 - 0.039 14.1 0.9 0.39 10.9 0.1 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sar8_2 PF03058.14 AJW71413.1 - 0.058 14.0 0.1 0.083 13.4 0.1 1.2 1 0 0 1 1 1 0 Sar8.2 family PIN_2 PF10130.9 AJW71413.1 - 0.066 13.5 0.1 0.085 13.1 0.1 1.2 1 0 0 1 1 1 0 PIN domain Nudix_N_2 PF14803.6 AJW71413.1 - 0.18 11.8 3.8 0.29 11.1 0.2 2.5 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 AJW71413.1 - 0.61 9.9 5.4 2.5 8.0 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 AJW71413.1 - 1.2 9.1 5.6 7.4 6.6 5.6 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-TFIIB PF13453.6 AJW71413.1 - 3 7.3 5.4 12 5.3 0.1 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger Rhodanese PF00581.20 AJW71414.1 - 2.5e-28 98.7 0.0 2.4e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain AFP_2 PF18815.1 AJW71414.1 - 0.015 15.5 0.0 0.062 13.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat ERCC4 PF02732.15 AJW71415.1 - 1.4e-24 87.1 0.0 2.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 AJW71415.1 - 5.1e-10 39.8 0.1 4.5e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 AJW71415.1 - 1.2e-07 31.2 0.1 0.0016 18.2 0.1 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 AJW71415.1 - 4.8e-05 23.4 0.0 0.00035 20.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AJW71415.1 - 0.00017 21.8 0.0 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.6 AJW71415.1 - 0.011 16.1 0.1 1.1 9.7 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 AJW71415.1 - 0.04 14.5 0.1 0.12 13.0 0.1 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Prefoldin_2 PF01920.20 AJW71416.1 - 1.4e-20 73.2 22.1 1.5e-20 73.1 22.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit D5_N PF08706.11 AJW71416.1 - 0.011 16.0 1.4 0.014 15.7 1.4 1.1 1 0 0 1 1 1 0 D5 N terminal like PsaN PF05479.11 AJW71416.1 - 0.051 13.8 0.9 0.13 12.4 0.2 1.8 1 1 1 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Ntox28 PF15605.6 AJW71416.1 - 0.12 12.6 0.4 0.12 12.6 0.4 2.1 2 0 0 2 2 2 0 Bacterial toxin 28 KIP1 PF07765.12 AJW71416.1 - 0.66 10.1 16.0 0.57 10.3 3.7 2.9 1 1 2 3 3 3 0 KIP1-like protein NEMP PF10225.9 AJW71416.1 - 0.91 9.1 3.1 0.43 10.2 1.0 1.4 1 1 1 2 2 2 0 NEMP family TP53IP5 PF15331.6 AJW71416.1 - 1.9 8.6 8.5 2.4 8.2 8.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4407 PF14362.6 AJW71416.1 - 3.3 7.0 9.7 4.5 6.5 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 AJW71416.1 - 4.8 5.7 13.4 5.9 5.4 13.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pcc1 PF09341.10 AJW71417.1 - 9.7e-05 22.4 0.1 0.00011 22.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Ribosomal_L37ae PF01780.19 AJW71418.1 - 9.3e-20 70.5 3.1 9.8e-20 70.4 3.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 AJW71418.1 - 0.00021 21.2 2.5 0.00021 21.2 2.5 1.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain C1_1 PF00130.22 AJW71418.1 - 0.0024 17.7 1.5 0.0035 17.2 1.5 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.12 AJW71418.1 - 0.023 14.2 2.2 0.045 13.3 2.2 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.7 AJW71418.1 - 0.043 13.8 1.7 0.082 13.0 1.7 1.4 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 AJW71418.1 - 0.054 13.4 3.8 0.15 12.0 3.8 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain C1_2 PF03107.16 AJW71418.1 - 0.055 13.8 0.5 0.068 13.5 0.5 1.2 1 0 0 1 1 1 0 C1 domain Zn-ribbon_8 PF09723.10 AJW71418.1 - 0.081 13.1 0.4 0.081 13.1 0.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 AJW71418.1 - 0.085 12.9 1.4 0.15 12.1 1.4 1.5 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RRN7 PF11781.8 AJW71418.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-H2C2_2 PF13465.6 AJW71418.1 - 0.11 12.9 3.1 1.9 9.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.6 AJW71418.1 - 0.17 11.3 0.1 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 AJW71418.1 - 0.62 9.9 3.7 5.1 7.0 0.5 2.3 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf_C2H2_10 PF18414.1 AJW71418.1 - 1.1 8.9 3.9 3.8 7.1 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger RNase_PH PF01138.21 AJW71419.1 - 4.1e-22 79.1 0.0 6.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AJW71419.1 - 2.8e-14 52.9 0.0 8.7e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glyco_hydro2_C5 PF18565.1 AJW71419.1 - 0.051 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 RNase_PH PF01138.21 AJW71420.1 - 1.9e-34 119.0 0.0 2.6e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AJW71420.1 - 1.9e-13 50.2 0.3 4.6e-13 49.0 0.3 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_6 PF15985.5 AJW71421.1 - 1.1e-06 28.8 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 AJW71421.1 - 1.4e-06 28.0 0.1 3.2e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 AJW71421.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AJW71421.1 - 0.029 14.2 0.1 0.097 12.6 0.1 1.9 2 0 0 2 2 2 0 KH domain DAP3 PF10236.9 AJW71421.1 - 0.075 12.2 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SBDS PF01172.18 AJW71422.1 - 3.4e-23 81.5 0.1 8.8e-23 80.2 0.1 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 AJW71422.1 - 1.4e-18 66.9 0.3 2.2e-18 66.4 0.3 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain EFG_C PF00679.24 AJW71422.1 - 0.0064 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF1189 PF06691.11 AJW71422.1 - 3.5 7.1 4.9 21 4.6 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) RNA_pol_A_bac PF01000.26 AJW71423.1 - 2.8e-25 88.9 0.0 5.5e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AJW71423.1 - 3.3e-13 48.9 0.0 4e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L18 PF17135.4 AJW71424.1 - 4.2e-06 26.3 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 AJW71424.1 - 0.00033 21.3 0.3 0.00052 20.7 0.3 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L13 PF00572.18 AJW71425.1 - 7.4e-11 42.4 1.2 8.7e-09 35.7 1.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Adhesin_E PF16747.5 AJW71425.1 - 0.099 12.7 0.4 1.4 8.9 0.0 2.5 1 1 1 2 2 2 0 Surface-adhesin protein E Ribosomal_S9 PF00380.19 AJW71426.1 - 1.1e-32 113.1 0.3 1.3e-32 112.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NTP_transferase PF00483.23 AJW71427.1 - 4.7e-18 65.7 0.1 5.6e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJW71427.1 - 3.8e-10 40.3 0.0 4.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AJW71427.1 - 0.013 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 AJW71427.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Aconitase_C PF00694.19 AJW71428.1 - 1.1e-35 122.9 0.0 1.9e-35 122.0 0.0 1.4 2 0 0 2 2 2 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AJW71428.1 - 3.3e-05 23.6 0.1 0.00054 19.7 0.1 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus FAD_syn PF06574.12 AJW71428.1 - 0.00016 21.6 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD synthetase Aconitase PF00330.20 AJW71429.1 - 3.8e-151 504.2 0.0 4.3e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AJW71430.1 - 8e-21 74.7 0.0 3.1e-20 72.8 0.0 1.9 1 1 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AJW71430.1 - 0.0026 17.4 0.1 0.021 14.5 0.1 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus MazE_antitoxin PF04014.18 AJW71430.1 - 0.052 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Aconitase PF00330.20 AJW71431.1 - 1.5e-93 314.4 3.2 1.3e-91 307.9 3.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) eRF1_2 PF03464.15 AJW71433.1 - 1.2e-11 45.1 1.0 1.2e-11 45.1 1.0 2.2 2 1 1 3 3 3 1 eRF1 domain 2 baeRF_family10 PF18854.1 AJW71433.1 - 1e-09 38.8 0.0 1.9e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 AJW71433.1 - 5.1e-09 36.5 0.0 7.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family3 PF18845.1 AJW71433.1 - 0.0045 17.3 0.1 0.0089 16.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 eRF1_3 PF03465.15 AJW71433.1 - 0.015 15.8 0.2 0.067 13.7 0.1 2.2 1 1 0 1 1 1 0 eRF1 domain 3 DUF3834 PF12916.7 AJW71433.1 - 0.028 13.7 0.1 0.058 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) F420_ligase PF01996.16 AJW71434.1 - 1.8e-42 145.4 0.2 2.4e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Nsp1_C PF05064.13 AJW71438.1 - 0.039 13.7 0.2 0.053 13.3 0.2 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Prefoldin PF02996.17 AJW71438.1 - 0.096 12.6 0.2 0.68 9.9 0.3 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF2854 PF11016.8 AJW71438.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) TPP_enzyme_C PF02775.21 AJW71439.1 - 1.5e-28 99.5 0.3 2.2e-28 99.0 0.3 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 AJW71439.1 - 1.3e-14 54.0 0.6 3.8e-13 49.4 0.6 2.4 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 AJW71440.1 - 5.8e-56 189.8 0.0 8.3e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AJW71440.1 - 3.9e-29 102.0 0.0 7.3e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 AJW71440.1 - 2.1e-12 47.2 0.0 4.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AJW71440.1 - 1.4e-05 25.0 0.0 3.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.18 AJW71440.1 - 0.0022 17.7 0.1 0.0038 16.9 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Ta0938 PF11494.8 AJW71440.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Ta0938 CSRNP_N PF16019.5 AJW71441.1 - 1.5 8.7 9.8 1.5 8.7 9.8 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus 2-Hacid_dh_C PF02826.19 AJW71442.1 - 1.2e-64 217.0 0.1 1.6e-64 216.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AJW71442.1 - 1.9e-31 108.5 0.0 2.1e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AJW71442.1 - 8.6e-09 35.8 0.2 2.1e-08 34.5 0.2 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AJW71442.1 - 4.5e-07 29.6 0.3 1.1e-06 28.4 0.2 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 AJW71442.1 - 0.00088 19.8 0.0 0.0024 18.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AJW71442.1 - 0.0049 17.0 0.1 0.0099 16.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 AJW71442.1 - 0.033 14.5 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain DUF2325 PF10087.9 AJW71442.1 - 0.13 12.4 0.6 1.2 9.3 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) HemS PF05171.12 AJW71443.1 - 1.6e-08 34.5 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Haemin-degrading HemS.ChuX domain ChuX_HutX PF06228.13 AJW71443.1 - 4.4e-08 33.0 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX DUF5104 PF17117.5 AJW71444.1 - 0.093 13.2 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) DAO PF01266.24 AJW71445.1 - 1.9e-44 152.7 0.0 2.3e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 AJW71445.1 - 2.4e-14 52.8 0.0 5.7e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 AJW71445.1 - 2.2e-06 27.1 0.5 0.025 13.8 0.1 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AJW71445.1 - 2e-05 25.1 1.9 0.082 13.5 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AJW71445.1 - 0.0016 18.6 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AJW71445.1 - 0.019 13.7 0.0 0.32 9.7 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 AJW71445.1 - 0.021 14.1 0.2 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AJW71445.1 - 0.028 13.5 0.0 4.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 AJW71445.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 AJW71445.1 - 0.095 13.0 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 AJW71445.1 - 0.23 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Usp PF00582.26 AJW71446.1 - 0.00015 22.3 0.0 0.00019 22.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family MAD PF05557.13 AJW71446.1 - 0.0012 17.3 0.2 0.0014 17.1 0.2 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF711 PF05167.12 AJW71446.1 - 0.016 14.1 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) B277 PF17623.2 AJW71446.1 - 0.068 12.2 3.4 0.068 12.2 2.7 1.3 1 1 0 1 1 1 0 Domain of unknown function LXG PF04740.12 AJW71448.1 - 0.0068 16.1 4.6 0.0083 15.9 4.6 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily ApoLp-III PF07464.11 AJW71448.1 - 0.25 11.5 14.3 0.29 11.2 14.3 1.0 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TPR_MLP1_2 PF07926.12 AJW71448.1 - 0.3 11.2 16.6 1.4 9.0 16.6 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CorA PF01544.18 AJW71448.1 - 0.44 9.8 2.0 0.51 9.6 2.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMPIT PF07851.13 AJW71448.1 - 0.6 9.3 11.1 0.69 9.1 11.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein GBP_C PF02841.14 AJW71448.1 - 0.88 8.9 15.9 1 8.7 15.9 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF948 PF06103.11 AJW71448.1 - 1.2 9.4 6.2 1.8 8.9 4.8 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AJW71448.1 - 1.6 8.9 9.9 11 6.2 3.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 AJW71448.1 - 2.3 7.7 11.4 2.8 7.4 11.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF444 PF04285.12 AJW71448.1 - 4.2 6.3 14.7 4.8 6.1 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DUF724 PF05266.14 AJW71448.1 - 5.1 6.9 14.6 5.9 6.7 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 AJW71448.1 - 5.2 6.5 14.5 5.3 6.5 14.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 AJW71448.1 - 5.7 4.7 10.4 6 4.7 10.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2228 PF10228.9 AJW71448.1 - 5.7 6.6 16.0 6.1 6.5 16.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) HAUS6_N PF14661.6 AJW71448.1 - 7.2 6.1 15.7 8 6.0 15.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Nup88 PF10168.9 AJW71448.1 - 7.5 4.2 13.5 8.4 4.1 13.5 1.1 1 0 0 1 1 1 0 Nuclear pore component Vps4_C PF09336.10 AJW71448.1 - 8 6.5 6.9 20 5.3 0.8 3.0 2 1 1 3 3 3 0 Vps4 C terminal oligomerisation domain FlgD_ig PF13860.6 AJW71450.1 - 0.0083 16.0 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 FlgD Ig-like domain Cupredoxin_1 PF13473.6 AJW71450.1 - 0.068 13.3 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain UL41A PF17591.2 AJW71450.1 - 0.094 12.8 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL41A TOBE_2 PF08402.10 AJW71450.1 - 0.17 12.0 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 TOBE domain TruB_N PF01509.18 AJW71451.1 - 3.1e-24 86.0 3.2 2.1e-14 54.1 0.0 3.5 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AJW71451.1 - 3.3e-19 68.8 0.1 1.4e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 AJW71451.1 - 7.7e-18 64.2 0.4 1.5e-17 63.3 0.4 1.5 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.12 AJW71451.1 - 1.1e-10 41.4 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain Cytidylate_kin2 PF13189.6 AJW71452.1 - 4.8e-14 52.9 0.0 1.2e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 AJW71452.1 - 1.3e-12 48.3 0.0 1.9e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AJW71452.1 - 4.5e-09 36.8 0.0 8.7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AJW71452.1 - 2.7e-07 30.6 0.1 3.1e-05 23.8 0.0 2.2 1 1 1 2 2 2 1 Cytidylate kinase SKI PF01202.22 AJW71452.1 - 1.8e-06 28.2 0.1 1e-05 25.7 0.1 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 AJW71452.1 - 1.2e-05 25.5 0.0 0.00049 20.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 AJW71452.1 - 3.8e-05 23.8 0.1 0.00012 22.2 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 AJW71452.1 - 0.00018 21.8 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AJW71452.1 - 0.00023 21.6 0.0 0.00037 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 AJW71452.1 - 0.0032 16.9 0.0 0.0062 16.0 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 dNK PF01712.19 AJW71452.1 - 0.0043 16.9 0.4 0.22 11.3 0.0 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase AAA_22 PF13401.6 AJW71452.1 - 0.0078 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AJW71452.1 - 0.011 16.2 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 AJW71452.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 AJW71452.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Hydin_ADK PF17213.3 AJW71452.1 - 0.025 14.9 0.0 0.034 14.4 0.0 1.5 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 AJW71452.1 - 0.028 14.2 0.1 0.066 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AJW71452.1 - 0.045 13.7 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF5528 PF17666.1 AJW71452.1 - 0.076 13.0 0.3 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5528) AAA_14 PF13173.6 AJW71452.1 - 0.085 12.9 0.2 0.22 11.5 0.0 2.0 2 2 1 3 3 3 0 AAA domain EMC3_TMCO1 PF01956.16 AJW71453.1 - 2.2e-15 56.8 15.5 2.9e-14 53.2 15.5 2.0 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like AAA_17 PF13207.6 AJW71454.1 - 1.6e-33 116.0 0.0 2.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AJW71454.1 - 8.7e-08 32.8 0.0 1.3e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AJW71454.1 - 9.7e-07 28.6 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KTI12 PF08433.10 AJW71454.1 - 1.6e-06 27.8 0.0 2.1e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 AJW71454.1 - 3.1e-05 24.0 1.8 0.00013 21.9 0.8 2.1 1 1 1 2 2 2 1 NTPase AAA_30 PF13604.6 AJW71454.1 - 3.4e-05 23.7 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AJW71454.1 - 6.6e-05 23.2 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AJW71454.1 - 0.0002 21.5 0.0 0.00027 21.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AJW71454.1 - 0.00038 20.7 0.1 0.00082 19.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 AJW71454.1 - 0.00077 19.3 0.1 0.0018 18.1 0.1 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 AJW71454.1 - 0.00084 19.4 0.1 0.0016 18.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 AJW71454.1 - 0.00096 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 AJW71454.1 - 0.0012 18.7 0.2 0.0021 18.0 0.2 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 AJW71454.1 - 0.0017 18.8 0.1 0.0053 17.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AJW71454.1 - 0.0019 18.2 0.0 0.0048 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain KdpD PF02702.17 AJW71454.1 - 0.0021 17.6 0.1 0.0027 17.2 0.1 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain 6PF2K PF01591.18 AJW71454.1 - 0.0026 17.1 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase NACHT PF05729.12 AJW71454.1 - 0.0027 17.6 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 AJW71454.1 - 0.0028 18.0 0.9 0.0078 16.6 0.9 1.9 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 AJW71454.1 - 0.0037 17.5 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 AJW71454.1 - 0.0037 16.8 0.1 0.0062 16.1 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 AJW71454.1 - 0.0038 16.6 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.17 AJW71454.1 - 0.0039 16.9 0.1 0.0086 15.8 0.1 1.8 1 1 0 1 1 1 1 Thymidylate kinase MeaB PF03308.16 AJW71454.1 - 0.0044 16.0 0.2 0.0074 15.3 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AJW71454.1 - 0.0056 17.2 0.4 0.0066 17.0 0.4 1.5 1 1 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.18 AJW71454.1 - 0.0075 16.0 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 AJW71454.1 - 0.0086 15.7 0.3 0.026 14.1 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 AJW71454.1 - 0.011 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 AJW71454.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Arf PF00025.21 AJW71454.1 - 0.017 14.6 1.4 0.049 13.1 0.4 2.1 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 AJW71454.1 - 0.022 15.2 0.0 0.036 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 AJW71454.1 - 0.022 14.1 0.3 0.053 12.8 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin MCM PF00493.23 AJW71454.1 - 0.035 13.2 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NB-ARC PF00931.22 AJW71454.1 - 0.038 13.2 0.5 0.035 13.3 0.5 1.4 1 1 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 AJW71454.1 - 0.039 13.9 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase TsaE PF02367.17 AJW71454.1 - 0.04 13.9 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 AJW71454.1 - 0.052 12.8 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 AJW71454.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 AJW71454.1 - 0.086 11.7 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 AJW71454.1 - 0.087 12.6 0.9 0.18 11.5 0.1 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.23 AJW71454.1 - 0.12 12.5 0.2 0.14 12.2 0.2 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 AJW71454.1 - 0.15 11.7 1.0 1.1 8.8 1.0 2.2 1 1 0 1 1 1 0 AAA domain SecY PF00344.20 AJW71455.1 - 2e-62 211.2 19.2 2.5e-62 210.9 19.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 AJW71455.1 - 4.7e-11 42.3 1.7 2e-10 40.3 1.7 2.2 1 0 0 1 1 1 1 Plug domain of Sec61p Ribosomal_L27A PF00828.19 AJW71456.1 - 3.6e-15 56.8 0.3 5.7e-15 56.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L30 PF00327.20 AJW71457.1 - 8.2e-11 41.6 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.20 AJW71458.1 - 1e-21 76.7 0.8 1.8e-21 75.9 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 AJW71458.1 - 5.1e-16 57.9 0.1 9e-16 57.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_L5e PF17144.4 AJW71459.1 - 2.8e-16 60.0 1.3 5e-13 49.4 0.4 2.6 1 1 1 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18p PF00861.22 AJW71459.1 - 0.038 14.3 0.3 0.054 13.9 0.3 1.2 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast OTCace_N PF02729.21 AJW71460.1 - 1e-51 174.9 0.0 1.4e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AJW71460.1 - 1.7e-49 167.9 0.0 2.5e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SRP54 PF00448.22 AJW71461.1 - 3.2e-69 232.5 0.9 5e-69 231.9 0.9 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AJW71461.1 - 6.3e-11 42.3 5.6 6.3e-11 42.3 5.6 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 AJW71461.1 - 5.5e-08 32.8 0.5 9.6e-08 32.0 0.1 1.5 2 0 0 2 2 1 1 AAA domain Trypan_PARP PF05887.11 AJW71461.1 - 4.4e-06 26.7 125.8 0.00012 22.1 59.0 3.0 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) Zeta_toxin PF06414.12 AJW71461.1 - 1e-05 24.9 0.1 1.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 AJW71461.1 - 0.00016 22.0 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AJW71461.1 - 0.00019 21.5 0.0 0.00046 20.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 AJW71461.1 - 0.00042 20.0 1.5 0.0039 16.8 1.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 AJW71461.1 - 0.0007 20.0 0.6 0.002 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 AJW71461.1 - 0.0019 17.4 0.1 0.003 16.8 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 AJW71461.1 - 0.0039 17.5 0.1 0.0066 16.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 AJW71461.1 - 0.0047 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 AJW71461.1 - 0.0048 16.6 0.2 0.018 14.7 0.0 2.1 3 0 0 3 3 2 1 Thymidylate kinase AAA_16 PF13191.6 AJW71461.1 - 0.005 17.3 0.0 0.0088 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 AJW71461.1 - 0.005 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 AJW71461.1 - 0.0057 16.8 0.0 0.0098 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AJW71461.1 - 0.0078 15.5 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KdpD PF02702.17 AJW71461.1 - 0.013 15.0 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA PF00004.29 AJW71461.1 - 0.015 15.7 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AJW71461.1 - 0.016 15.1 0.3 0.76 9.7 0.3 2.3 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.6 AJW71461.1 - 0.017 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPP_enzyme_M PF00205.22 AJW71461.1 - 0.017 14.9 0.5 0.22 11.2 0.2 2.7 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain AAA_15 PF13175.6 AJW71461.1 - 0.022 14.5 0.0 0.022 14.5 0.0 2.3 2 1 1 3 3 2 0 AAA ATPase domain AAA_14 PF13173.6 AJW71461.1 - 0.026 14.6 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AJW71461.1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 AJW71461.1 - 0.033 14.0 0.1 0.086 12.6 0.0 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 AJW71461.1 - 0.05 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 AJW71461.1 - 0.057 13.3 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AJW71461.1 - 0.058 12.9 0.1 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 AJW71461.1 - 0.062 13.4 0.4 0.26 11.4 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase SPOUT_MTase PF02590.17 AJW71461.1 - 0.066 13.2 0.1 0.27 11.2 0.0 1.8 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase MobB PF03205.14 AJW71461.1 - 0.079 12.9 0.2 0.19 11.6 0.2 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 AJW71461.1 - 0.097 12.7 1.5 0.44 10.5 1.1 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TK PF00265.18 AJW71461.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase DAP3 PF10236.9 AJW71461.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MeaB PF03308.16 AJW71461.1 - 0.12 11.4 0.1 0.34 9.8 0.1 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB B12-binding PF02310.19 AJW71461.1 - 0.13 12.3 0.3 1.1 9.3 0.2 2.3 1 1 1 2 2 2 0 B12 binding domain Prefoldin PF02996.17 AJW71462.1 - 1.7e-17 63.4 4.8 1.5e-16 60.4 4.8 2.1 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 AJW71462.1 - 0.0036 17.2 5.8 0.0051 16.7 0.2 2.3 2 1 0 2 2 2 1 Prefoldin subunit Phage_P2_GpU PF06995.11 AJW71462.1 - 0.045 13.4 0.5 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Phage P2 GpU Paralemmin PF03285.15 AJW71462.1 - 0.066 12.8 2.0 1.8 8.1 0.2 2.0 2 0 0 2 2 2 0 Paralemmin DUF1840 PF08895.11 AJW71462.1 - 0.073 13.4 1.9 0.19 12.1 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) OmpH PF03938.14 AJW71462.1 - 0.086 13.2 9.9 0.26 11.6 2.5 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SKA2 PF16740.5 AJW71462.1 - 0.2 11.5 6.0 0.14 12.0 2.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Dynactin_p22 PF07426.11 AJW71462.1 - 0.32 10.8 4.6 0.45 10.4 0.6 2.5 2 1 0 2 2 2 0 Dynactin subunit p22 AIP3 PF03915.13 AJW71462.1 - 0.38 9.8 3.8 0.14 11.3 1.1 1.5 2 0 0 2 2 2 0 Actin interacting protein 3 ABC_tran_CTD PF16326.5 AJW71462.1 - 0.42 10.9 9.3 0.15 12.3 2.8 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain PilO PF04350.13 AJW71462.1 - 0.55 10.4 6.8 0.24 11.6 2.9 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO CENP-F_leu_zip PF10473.9 AJW71462.1 - 0.72 9.9 6.4 1.5 8.9 0.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3947 PF13135.6 AJW71462.1 - 1.9 8.8 8.8 2.2 8.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Sod_Fe_C PF02777.18 AJW71463.1 - 2.6e-39 133.5 0.0 4.2e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AJW71463.1 - 3.7e-29 101.0 0.5 6.9e-29 100.2 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_S8 PF00082.22 AJW71464.1 - 1e-54 185.9 0.4 1.5e-54 185.3 0.4 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 AJW71464.1 - 6.8e-14 51.7 0.1 2.4e-13 49.9 0.1 1.9 1 0 0 1 1 1 1 PA domain PEPCK_ATP PF01293.20 AJW71465.1 - 2.7e-212 705.5 0.0 3.1e-212 705.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ribosomal_L32e PF01655.18 AJW71466.1 - 1.7e-33 115.2 0.1 2.1e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L19e PF01280.20 AJW71467.1 - 7.8e-41 139.5 6.6 9.3e-41 139.3 6.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DNA_binding_1 PF01035.20 AJW71468.1 - 5.5e-28 96.9 0.0 6.6e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain tRNA_deacylase PF04414.12 AJW71469.1 - 5.7e-63 212.1 0.0 7.4e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase ID PF18543.1 AJW71469.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Intracellular delivery domain MbeD_MobD PF04899.12 AJW71469.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 MbeD/MobD like SecE PF00584.20 AJW71470.1 - 4.1e-07 29.8 0.0 4.8e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Spt5-NGN PF03439.13 AJW71471.1 - 1.4e-20 72.9 0.0 2.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 AJW71471.1 - 1.7e-06 27.8 0.4 3.3e-06 26.9 0.4 1.5 1 0 0 1 1 1 1 KOW motif NusG PF02357.19 AJW71471.1 - 0.16 12.5 0.0 1.5 9.4 0.0 2.1 1 1 0 1 1 1 0 Transcription termination factor nusG Ribosomal_L11_N PF03946.14 AJW71472.1 - 3.1e-22 78.2 0.3 7e-22 77.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AJW71472.1 - 4.3e-18 65.6 1.4 7.1e-18 64.9 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyt_bd_oxida_I PF01654.17 AJW71473.1 - 0.00077 18.2 0.5 0.00088 18.0 0.5 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Phage_holin_3_6 PF07332.11 AJW71473.1 - 0.0056 16.7 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III LtrA PF06772.11 AJW71473.1 - 0.015 14.6 0.2 0.017 14.4 0.2 1.0 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Tetraspanin PF00335.20 AJW71473.1 - 0.17 11.6 0.1 0.22 11.2 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family HATPase_c PF02518.26 AJW71474.1 - 9.3e-19 68.0 1.8 1.2e-17 64.4 0.4 2.6 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW71474.1 - 1.4e-10 41.1 1.2 3.1e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AJW71474.1 - 4.1e-07 29.9 0.3 1.4e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AJW71474.1 - 5.8e-05 22.9 0.4 0.00018 21.4 0.4 1.9 1 0 0 1 1 1 1 GHKL domain Ret2_MD PF18528.1 AJW71474.1 - 0.023 15.1 0.4 2 8.8 0.0 2.7 1 1 1 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain HAMP PF00672.25 AJW71474.1 - 0.05 14.0 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 HAMP domain JAB PF01398.21 AJW71474.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4600 PF15372.6 AJW71474.1 - 0.072 13.5 4.0 3.6 8.0 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Ca_bind_SSO6904 PF18249.1 AJW71474.1 - 0.36 11.2 8.5 0.39 11.1 0.3 3.8 3 1 1 4 4 4 0 Calcium binding protein SSO6904 TMPIT PF07851.13 AJW71474.1 - 0.48 9.6 2.1 0.86 8.8 2.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein Phosphonate-bd PF12974.7 AJW71475.1 - 2e-44 152.0 0.0 2.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Rad1 PF02144.16 AJW71475.1 - 0.063 12.3 0.1 0.79 8.7 0.0 2.1 1 1 1 2 2 2 0 Repair protein Rad1/Rec1/Rad17 Response_reg PF00072.24 AJW71476.1 - 7e-24 84.2 0.3 7.9e-24 84.0 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AJW71476.1 - 0.016 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain TPP_enzyme_N PF02776.18 AJW71477.1 - 3.5e-60 202.5 0.0 2e-59 200.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AJW71477.1 - 3e-37 127.8 0.0 8.8e-37 126.2 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AJW71477.1 - 5.1e-34 117.0 0.1 1e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 AJW71477.1 - 0.0024 17.7 0.0 0.0076 16.0 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF4097 PF13349.6 AJW71478.1 - 0.052 12.9 0.1 0.058 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative adhesin AsnC_trans_reg PF01037.21 AJW71480.1 - 4e-16 58.7 0.0 5.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AJW71480.1 - 3.1e-06 26.6 0.1 5e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AJW71480.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain B-block_TFIIIC PF04182.12 AJW71480.1 - 0.002 18.2 0.1 0.003 17.7 0.1 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.22 AJW71480.1 - 0.0093 15.9 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AJW71480.1 - 0.022 14.7 0.5 0.051 13.5 0.1 1.8 2 0 0 2 2 2 0 HTH domain Ribosomal_S25 PF03297.15 AJW71480.1 - 0.029 14.6 0.4 0.062 13.5 0.1 1.6 2 0 0 2 2 2 0 S25 ribosomal protein TrmB PF01978.19 AJW71480.1 - 0.04 13.8 0.1 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AJW71480.1 - 0.042 13.7 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_psq PF05225.16 AJW71480.1 - 0.044 13.5 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Ribosomal_L1 PF00687.21 AJW71481.1 - 5.2e-40 137.4 2.5 6.2e-40 137.1 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RL10P_insert PF17777.1 AJW71482.1 - 4.4e-20 71.5 0.1 1.5e-19 69.7 0.1 2.0 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 AJW71482.1 - 2.4e-19 69.3 1.5 6.1e-19 68.0 1.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 HPHLAWLY PF14925.6 AJW71482.1 - 0.023 13.4 0.8 0.04 12.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function Ribosomal_60s PF00428.19 AJW71482.1 - 0.069 13.8 2.5 0.078 13.6 1.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein dCache_1 PF02743.18 AJW71483.1 - 0.0099 15.7 1.8 0.015 15.1 1.8 1.3 1 1 0 1 1 1 1 Cache domain HN PF00423.19 AJW71483.1 - 0.1 11.4 5.4 0.15 10.9 5.4 1.2 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase HATPase_c PF02518.26 AJW71484.1 - 3.4e-16 59.7 0.2 7.1e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AJW71484.1 - 7e-11 41.9 0.1 1.5e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 GHKL domain HisKA PF00512.25 AJW71484.1 - 4.3e-08 33.1 0.1 8.9e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HMA PF00403.26 AJW71484.1 - 0.013 16.0 0.3 0.11 13.0 0.2 2.5 3 0 0 3 3 3 0 Heavy-metal-associated domain Mfa_like_1 PF13149.6 AJW71484.1 - 0.018 15.1 0.4 0.024 14.7 0.4 1.2 1 0 0 1 1 1 0 Fimbrillin-like RNA_pol_A_CTD PF03118.15 AJW71484.1 - 0.18 11.6 1.1 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Response_reg PF00072.24 AJW71485.1 - 5e-26 91.1 0.0 5.5e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF432 PF04254.13 AJW71489.1 - 1e-25 90.3 0.0 1.9e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF432) MS_channel PF00924.18 AJW71490.1 - 1.5e-45 155.3 4.6 2.2e-45 154.8 4.6 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel FecCD PF01032.18 AJW71490.1 - 0.0026 16.8 7.0 0.0026 16.8 7.0 1.7 1 1 0 1 1 1 1 FecCD transport family End_beta_propel PF12217.8 AJW71490.1 - 0.094 11.4 0.1 0.23 10.1 0.0 1.6 1 1 1 2 2 2 0 Catalytic beta propeller domain of bacteriophage endosialidase Ribosomal_S21 PF01165.20 AJW71490.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 FtsX PF02687.21 AJW71490.1 - 5.6 7.5 12.1 3.4 8.2 3.7 2.3 1 1 1 2 2 2 0 FtsX-like permease family TM_helix PF05552.12 AJW71490.1 - 6.1 6.9 9.9 0.98 9.5 4.1 2.6 3 0 0 3 3 3 0 Conserved TM helix HATPase_c PF02518.26 AJW71491.1 - 4.6e-20 72.2 0.5 1.1e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 AJW71491.1 - 1.9e-09 38.2 0.0 3.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 AJW71491.1 - 1.1e-08 34.9 0.6 2.9e-08 33.6 0.6 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW71491.1 - 6.6e-06 26.0 3.2 6.7e-05 22.7 0.0 2.9 3 0 0 3 3 3 1 GHKL domain GAF_2 PF13185.6 AJW71491.1 - 6e-05 23.4 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 AJW71491.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain GAF_3 PF13492.6 AJW71491.1 - 0.045 14.1 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 GAF domain ApoLp-III PF07464.11 AJW71491.1 - 0.063 13.4 11.3 0.54 10.3 5.9 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Serine_rich PF08824.10 AJW71491.1 - 0.16 12.0 7.8 2.1 8.3 0.1 2.5 1 1 1 2 2 2 0 Serine rich protein interaction domain ACDC PF14733.6 AJW71491.1 - 0.45 10.9 5.9 0.84 10.0 1.8 2.6 2 0 0 2 2 2 0 AP2-coincident C-terminal PP2C_C PF07830.13 AJW71491.1 - 0.71 10.4 4.6 0.6 10.6 0.3 2.6 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain FAM76 PF16046.5 AJW71491.1 - 2.2 7.6 7.5 3.5 6.9 7.5 1.3 1 0 0 1 1 1 0 FAM76 protein DM13 PF10517.9 AJW71492.1 - 2.9e-19 69.6 0.0 4.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Electron transfer DM13 H_kinase_N PF12282.8 AJW71492.1 - 0.064 13.2 0.3 0.14 12.1 0.3 1.6 1 1 0 1 1 1 0 Signal transduction histidine kinase O-antigen_lig PF13425.6 AJW71492.1 - 0.18 10.5 4.0 0.22 10.3 4.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HATPase_c PF02518.26 AJW71493.1 - 5.4e-19 68.8 0.3 1e-18 67.9 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AJW71493.1 - 2.4e-06 27.4 0.1 2.4e-06 27.4 0.1 1.8 2 1 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 AJW71493.1 - 1.2e-05 25.1 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW71493.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Glyoxalase PF00903.25 AJW71494.1 - 2.4e-15 56.9 0.0 2.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AJW71494.1 - 1.3e-08 35.0 0.0 1.2e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AJW71494.1 - 2.6e-05 24.1 0.1 4.6e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AJW71494.1 - 0.00063 20.5 0.0 0.00081 20.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AJW71494.1 - 0.039 14.1 0.0 0.093 12.8 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Pfk_N PF18468.1 AJW71494.1 - 0.08 13.4 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast Med29 PF11568.8 AJW71495.1 - 0.064 13.5 0.0 0.068 13.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 29 Cupin_2 PF07883.11 AJW71496.1 - 8.6e-10 38.2 0.6 1.3e-09 37.6 0.6 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AJW71496.1 - 0.0019 17.9 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 AJW71496.1 - 0.0021 17.9 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 AJW71496.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain MannoseP_isomer PF01050.18 AJW71496.1 - 0.02 14.8 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase ARD PF03079.14 AJW71496.1 - 0.059 13.6 0.1 0.15 12.3 0.0 1.7 1 1 1 2 2 2 0 ARD/ARD' family Lyx_isomer PF07385.12 AJW71496.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 D-lyxose isomerase zf-CDGSH PF09360.10 AJW71497.1 - 1.1e-10 41.5 2.6 2e-10 40.7 2.6 1.5 1 1 0 1 1 1 1 Iron-binding zinc finger CDGSH type PMG PF05287.12 AJW71498.1 - 0.15 12.1 0.0 14 5.7 0.0 2.9 2 1 1 3 3 3 0 PMG protein Rhodanese PF00581.20 AJW71499.1 - 3.1e-25 88.8 0.0 2.2e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 AJW71499.1 - 1.9e-20 73.7 2.4 1.3e-19 70.9 2.4 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 AJW71499.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJW71499.1 - 0.0047 16.5 0.1 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Rhodanese PF00581.20 AJW71500.1 - 8.3e-10 39.1 0.0 1e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain MMU163 PF17119.5 AJW71501.1 - 0.065 12.4 4.4 0.077 12.1 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Eno-Rase_FAD_bd PF07055.12 AJW71501.1 - 0.13 12.7 1.5 0.21 12.0 0.5 2.0 1 1 1 2 2 2 0 Enoyl reductase FAD binding domain HU-DNA_bdg PF14848.6 AJW71501.1 - 0.73 9.9 7.9 1.4 9.0 0.3 2.4 1 1 1 2 2 2 0 DNA-binding domain Tape_meas_lam_C PF09718.10 AJW71501.1 - 0.88 9.7 4.0 4.7 7.4 0.2 2.9 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Cor1 PF04803.12 AJW71501.1 - 0.98 9.6 19.0 9.2 6.5 10.7 3.3 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Mitofilin PF09731.9 AJW71501.1 - 1.8 7.3 28.3 2.4 6.9 27.2 1.6 1 1 0 1 1 1 0 Mitochondrial inner membrane protein SLATT_4 PF18186.1 AJW71501.1 - 3.1 7.4 17.8 0.044 13.4 4.1 2.8 2 2 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 V-ATPase_G PF03179.15 AJW71501.1 - 3.8 8.1 29.0 78 3.9 21.7 3.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4771 PF15995.5 AJW71501.1 - 4.4 7.5 10.2 1.4 9.2 5.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4771) Phage_TAC_4 PF08748.11 AJW71501.1 - 5.4 7.3 13.6 28 5.0 13.6 2.1 1 1 0 1 1 1 0 Phage tail assembly chaperone Glyc_hyd_38C_2 PF18230.1 AJW71502.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain Epimerase PF01370.21 AJW71506.1 - 3.3e-22 79.2 0.0 4.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJW71506.1 - 3.2e-14 53.1 0.0 2.3e-13 50.3 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJW71506.1 - 1.2e-13 50.7 0.0 6.9e-13 48.2 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AJW71506.1 - 2.5e-12 46.5 0.0 1.5e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AJW71506.1 - 1.6e-11 43.9 0.0 5.9e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AJW71506.1 - 6e-08 32.2 0.0 8.4e-06 25.1 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AJW71506.1 - 9e-08 32.2 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AJW71506.1 - 8.4e-05 22.2 0.1 0.00029 20.5 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family DUF1731 PF08338.11 AJW71506.1 - 0.016 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) adh_short PF00106.25 AJW71506.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF389 PF04087.14 AJW71507.1 - 7.4e-30 103.8 15.7 7.4e-30 103.8 15.7 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF389) Asp4 PF16996.5 AJW71507.1 - 0.051 13.4 0.0 0.051 13.4 0.0 3.6 4 0 0 4 4 4 0 Accessory secretory protein Sec Asp4 CcdA PF07362.12 AJW71507.1 - 0.17 12.3 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA TssN PF17555.2 AJW71507.1 - 0.64 9.4 13.3 0.44 9.9 3.5 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Usp PF00582.26 AJW71508.1 - 2.4e-30 105.9 0.0 2.7e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Arg_tRNA_synt_N PF03485.16 AJW71508.1 - 0.099 13.2 0.4 0.39 11.3 0.4 2.0 1 1 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF3796 PF12676.7 AJW71509.1 - 0.36 11.3 11.5 0.67 10.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3796) DUF3392 PF11872.8 AJW71509.1 - 3.1 8.1 8.3 0.73 10.1 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) DUF3179 PF11376.8 AJW71510.1 - 5.2e-107 357.5 0.0 6.1e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3179) PBP_like_2 PF12849.7 AJW71511.1 - 3.2e-54 184.5 1.0 4.9e-54 183.9 1.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 AJW71511.1 - 2.3e-14 54.1 0.4 2.3e-14 54.1 0.4 1.7 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AJW71511.1 - 1.1e-06 27.9 0.0 4.4e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 PBP superfamily domain PhoU PF01895.19 AJW71512.1 - 3.6e-17 62.6 15.3 4.6e-15 55.8 0.8 3.2 3 0 0 3 3 3 2 PhoU domain MazE_antitoxin PF04014.18 AJW71512.1 - 0.00041 20.2 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin DUF4735 PF15882.5 AJW71512.1 - 0.069 12.6 0.4 0.13 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) MucBP_2 PF17965.1 AJW71512.1 - 0.12 12.9 0.9 1.3 9.6 0.2 2.4 2 0 0 2 2 2 0 Mucin binding domain hnRNP_Q_AcD PF18360.1 AJW71512.1 - 0.2 11.6 1.9 0.37 10.8 0.5 2.3 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain tRNA-synt_His PF13393.6 AJW71512.1 - 0.24 10.6 3.5 0.15 11.3 0.6 1.9 2 0 0 2 2 2 0 Histidyl-tRNA synthetase DUF1068 PF06364.12 AJW71512.1 - 1.1 9.1 4.4 0.32 10.9 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) BPD_transp_1 PF00528.22 AJW71513.1 - 5.3e-18 65.4 17.4 5.3e-18 65.4 17.4 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF1011 PF06237.12 AJW71513.1 - 0.2 12.0 3.6 19 5.6 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1011) BPD_transp_1 PF00528.22 AJW71514.1 - 2.2e-18 66.7 23.9 2.4e-18 66.5 15.2 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.8 AJW71514.1 - 2.7 8.2 6.1 0.62 10.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) ABC_tran PF00005.27 AJW71515.1 - 8.4e-30 104.1 0.0 1.3e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJW71515.1 - 6.9e-12 45.8 0.0 6.7e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AJW71515.1 - 2.1e-10 40.4 0.1 5.3e-10 39.1 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AJW71515.1 - 7.8e-06 26.2 0.0 2.2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AJW71515.1 - 3.8e-05 23.6 0.3 0.00031 20.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AJW71515.1 - 0.00028 21.5 2.0 0.0011 19.5 2.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AJW71515.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 AJW71515.1 - 0.0016 18.4 0.4 0.093 12.6 0.4 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 AJW71515.1 - 0.0028 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain TniB PF05621.11 AJW71515.1 - 0.0035 16.8 0.1 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 Bacterial TniB protein AAA_29 PF13555.6 AJW71515.1 - 0.005 16.5 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AJW71515.1 - 0.006 16.2 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AJW71515.1 - 0.0088 15.8 0.0 0.058 13.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AJW71515.1 - 0.0092 16.4 0.0 0.025 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 AJW71515.1 - 0.0096 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 AJW71515.1 - 0.015 15.8 0.0 0.024 15.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AJW71515.1 - 0.016 15.0 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 AJW71515.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 AJW71515.1 - 0.041 14.0 0.0 0.084 13.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 AJW71515.1 - 0.072 13.4 0.1 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AJW71515.1 - 0.075 13.5 3.6 0.62 10.5 0.2 3.0 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AJW71515.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 AJW71515.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 AJW71515.1 - 0.11 12.0 0.2 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 AJW71515.1 - 0.11 11.8 1.5 0.31 10.3 0.1 2.2 2 1 1 3 3 3 0 KaiC AAA_28 PF13521.6 AJW71515.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AJW71515.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoU PF01895.19 AJW71516.1 - 2.8e-20 72.6 8.1 3.8e-11 43.3 0.2 2.5 3 0 0 3 3 3 2 PhoU domain DUF2116 PF09889.9 AJW71517.1 - 0.00039 20.3 0.7 0.0006 19.7 0.7 1.3 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2113 PF09886.9 AJW71517.1 - 0.0065 15.8 0.0 0.0068 15.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2113) RRT14 PF17075.5 AJW71517.1 - 0.029 14.5 1.4 0.033 14.3 1.4 1.2 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 zinc_ribbon_2 PF13240.6 AJW71517.1 - 0.073 12.8 3.3 0.16 11.7 3.3 1.7 1 1 0 1 1 1 0 zinc-ribbon domain PLATZ PF04640.14 AJW71517.1 - 0.37 11.4 5.7 0.19 12.4 2.6 1.9 2 0 0 2 2 2 0 PLATZ transcription factor zf-BED PF02892.15 AJW71517.1 - 2.4 8.2 6.2 3.9 7.6 5.6 1.9 1 1 1 2 2 2 0 BED zinc finger Response_reg PF00072.24 AJW71518.1 - 4.9e-20 71.8 1.4 5.3e-20 71.7 0.9 1.2 1 1 0 1 1 1 1 Response regulator receiver domain 3HCDH_RFF PF18321.1 AJW71518.1 - 0.19 12.2 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF4898 PF16239.5 AJW71519.1 - 0.057 13.4 0.1 5.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4898) ArlS_N PF18719.1 AJW71519.1 - 0.079 13.2 2.0 0.41 10.9 0.1 2.0 1 1 1 2 2 2 0 ArlS sensor domain Hexapep PF00132.24 AJW71520.1 - 1.3e-16 59.6 21.5 1.6e-07 30.8 2.3 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJW71520.1 - 5.5e-05 22.8 27.8 0.015 15.0 6.5 5.1 4 2 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AJW71520.1 - 0.053 12.5 1.1 0.089 11.7 1.1 1.4 1 1 0 1 1 1 0 L-fucokinase GPAT_N PF14829.6 AJW71520.1 - 0.13 12.3 0.3 1.3 9.0 0.0 2.4 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal DUF4954 PF16314.5 AJW71520.1 - 1.2 7.1 8.7 2.7 6.0 8.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) P-II PF00543.22 AJW71522.1 - 2.7e-21 76.1 1.0 3e-21 75.9 1.0 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Sod_Fe_C PF02777.18 AJW71523.1 - 1.5e-40 137.5 0.2 2.4e-40 136.8 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AJW71523.1 - 1.1e-27 96.2 0.4 2e-27 95.5 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Usp PF00582.26 AJW71524.1 - 7e-18 65.5 0.0 8.8e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family RNA_Me_trans PF04252.13 AJW71524.1 - 0.0059 16.2 0.1 0.0075 15.9 0.1 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase NAD_Gly3P_dh_N PF01210.23 AJW71524.1 - 0.036 14.1 0.2 0.046 13.7 0.2 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TcpS PF17456.2 AJW71524.1 - 0.087 12.9 6.6 0.21 11.6 6.6 1.7 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S Usp PF00582.26 AJW71525.1 - 7.6e-11 42.7 0.0 9.4e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family mRNA_cap_C PF03919.15 AJW71525.1 - 0.097 13.3 2.0 0.55 10.9 0.1 2.4 1 1 1 2 2 2 0 mRNA capping enzyme, C-terminal domain Methyltransf_24 PF13578.6 AJW71525.1 - 0.11 13.5 0.0 0.17 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TM_helix PF05552.12 AJW71526.1 - 1.1e-15 57.4 7.0 3e-08 33.5 1.5 3.3 2 0 0 2 2 2 2 Conserved TM helix MS_channel PF00924.18 AJW71526.1 - 1.2e-07 31.5 9.5 1.2e-07 31.5 9.5 2.3 2 0 0 2 2 2 1 Mechanosensitive ion channel TM1506 PF08973.10 AJW71526.1 - 0.00083 19.0 0.1 0.0033 17.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1893) DDDD PF10161.9 AJW71526.1 - 0.26 11.1 2.3 12 5.8 0.1 2.9 2 0 0 2 2 2 0 Putative mitochondrial precursor protein FtsX PF02687.21 AJW71526.1 - 0.6 10.6 28.1 1.4 9.4 1.4 3.9 3 1 1 4 4 4 0 FtsX-like permease family CPP1-like PF11833.8 AJW71526.1 - 3.4 7.3 8.5 3.5 7.2 1.1 2.7 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Acetyltransf_1 PF00583.25 AJW71528.1 - 0.0038 17.5 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PDEase_I PF00233.19 AJW71528.1 - 0.0042 16.8 1.6 0.0088 15.8 1.6 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 AJW71529.1 - 4.2e-19 68.9 0.1 5.9e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MS_channel PF00924.18 AJW71530.1 - 3.7e-26 91.9 8.9 1.1e-25 90.4 8.9 1.8 1 1 0 1 1 1 1 Mechanosensitive ion channel Arc_PepC PF06819.11 AJW71531.1 - 0.085 13.0 3.3 0.089 12.9 3.3 1.0 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain TFIIB PF00382.19 AJW71532.1 - 9.4e-25 86.5 0.1 3.6e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 AJW71532.1 - 1.1e-05 24.8 1.7 2.4e-05 23.7 1.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 AJW71532.1 - 0.0031 17.3 0.4 0.0067 16.2 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_10 PF04967.12 AJW71532.1 - 0.033 14.0 0.4 18 5.2 0.0 3.6 4 0 0 4 4 4 0 HTH DNA binding domain HTH_36 PF13730.6 AJW71532.1 - 0.048 13.6 1.2 54 3.9 0.0 4.3 4 1 1 5 5 5 0 Helix-turn-helix domain Cyclin_C PF02984.19 AJW71532.1 - 0.086 12.9 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain HSP20 PF00011.21 AJW71533.1 - 1e-10 41.7 0.6 1.7e-09 37.7 0.6 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AJW71533.1 - 3.7e-10 39.2 0.1 5.6e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 AJW71533.1 - 2.8e-05 24.4 0.1 4.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain zf-C3HC4_3 PF13920.6 AJW71534.1 - 0.0074 16.1 1.9 0.0074 16.1 1.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 AJW71534.1 - 0.015 15.4 6.7 0.019 15.1 6.7 1.2 1 0 0 1 1 1 0 FYVE zinc finger zf-C3H2C3 PF17122.5 AJW71534.1 - 0.05 13.7 4.1 0.05 13.7 4.1 1.9 2 0 0 2 2 2 0 Zinc-finger DZR PF12773.7 AJW71534.1 - 0.079 13.0 8.8 0.2 11.7 8.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 AJW71534.1 - 0.24 11.4 8.1 0.71 9.9 8.1 1.8 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_2 PF13240.6 AJW71534.1 - 0.31 10.8 8.2 7.3 6.5 5.0 3.1 2 1 1 3 3 3 0 zinc-ribbon domain HypA PF01155.19 AJW71534.1 - 0.35 10.9 6.2 1.8 8.6 6.2 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Usp PF00582.26 AJW71535.1 - 5.3e-23 82.1 0.0 6.7e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DoxX PF07681.12 AJW71537.1 - 1.4e-10 41.6 2.0 1.4e-10 41.6 2.0 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 AJW71537.1 - 1.9e-06 27.9 1.0 3.4e-06 27.1 1.0 1.3 1 0 0 1 1 1 1 TQO small subunit DoxD DuoxA PF10204.9 AJW71537.1 - 0.0028 16.7 0.7 0.0035 16.4 0.7 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor DoxX_2 PF13564.6 AJW71537.1 - 0.029 14.5 4.9 0.06 13.5 4.9 1.7 1 1 0 1 1 1 0 DoxX-like family DUF2892 PF11127.8 AJW71537.1 - 9.1 6.4 8.6 30 4.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) PknG_rubred PF16919.5 AJW71538.1 - 0.34 11.1 2.7 1.4 9.1 0.5 2.0 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain Usp PF00582.26 AJW71539.1 - 4.8e-28 98.4 1.0 6e-28 98.1 1.0 1.1 1 0 0 1 1 1 1 Universal stress protein family GldM_N PF12081.8 AJW71539.1 - 0.05 13.7 0.9 0.065 13.3 0.5 1.3 2 0 0 2 2 2 0 GldM N-terminal domain FliT PF05400.13 AJW71539.1 - 0.057 14.2 0.6 0.12 13.2 0.6 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Sec23_trunk PF04811.15 AJW71539.1 - 0.068 12.7 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain HTH_40 PF14493.6 AJW71539.1 - 0.089 13.3 1.5 5.3 7.6 0.2 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain Amidohydro_1 PF01979.20 AJW71539.1 - 0.12 11.6 0.9 0.3 10.4 0.9 1.7 1 1 0 1 1 1 0 Amidohydrolase family B277 PF17623.2 AJW71540.1 - 0.017 14.2 0.4 0.017 14.2 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function Phage_holin_1 PF04531.13 AJW71541.1 - 0.086 13.4 5.8 0.35 11.4 0.5 2.3 1 1 0 2 2 2 0 Bacteriophage holin Na_Ca_ex PF01699.24 AJW71542.1 - 5e-53 179.1 43.6 5.7e-27 94.5 19.4 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TMEM61 PF15105.6 AJW71542.1 - 0.0091 15.9 0.1 5.2 6.9 0.1 2.3 2 0 0 2 2 2 2 TMEM61 protein family PepSY_TM PF03929.16 AJW71542.1 - 0.069 12.8 3.3 0.26 10.9 0.3 2.4 2 0 0 2 2 2 0 PepSY-associated TM region DUF4479 PF14794.6 AJW71542.1 - 0.12 12.2 0.5 6.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) Zn-ribbon_8 PF09723.10 AJW71543.1 - 0.00011 22.2 1.4 0.00014 21.9 1.4 1.2 1 0 0 1 1 1 1 Zinc ribbon domain zf-ribbon_3 PF13248.6 AJW71543.1 - 0.00078 18.8 0.6 0.67 9.5 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AJW71543.1 - 0.0019 17.7 1.8 0.16 11.5 0.2 2.2 1 1 1 2 2 2 2 TFIIB zinc-binding HypA PF01155.19 AJW71543.1 - 0.0021 18.1 0.4 0.0022 18.0 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRN7 PF11781.8 AJW71543.1 - 0.0023 17.6 1.1 1.9 8.3 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF1451 PF07295.11 AJW71543.1 - 0.0024 17.9 0.9 0.0029 17.6 0.9 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain zf-C2HC5 PF06221.13 AJW71543.1 - 0.0035 17.3 0.6 0.0038 17.2 0.6 1.1 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-C2H2_6 PF13912.6 AJW71543.1 - 0.0048 16.9 1.8 0.82 9.7 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger RNA_POL_M_15KD PF02150.16 AJW71543.1 - 0.0056 16.5 0.6 0.0082 16.0 0.6 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 AJW71543.1 - 0.0075 16.3 0.8 0.0093 16.0 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon IBR PF01485.21 AJW71543.1 - 0.022 15.0 0.9 0.024 14.8 0.9 1.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RecR PF02132.15 AJW71543.1 - 0.023 14.3 3.0 0.5 10.0 3.0 2.1 1 1 0 1 1 1 0 RecR protein ADK_lid PF05191.14 AJW71543.1 - 0.023 14.6 2.1 0.2 11.7 2.1 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid Rtf2 PF04641.12 AJW71543.1 - 0.028 13.8 0.2 0.028 13.8 0.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_1 PF14446.6 AJW71543.1 - 0.037 14.0 1.1 0.046 13.7 1.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TackOD1 PF18551.1 AJW71543.1 - 0.039 13.6 1.6 0.058 13.1 1.6 1.3 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 zf-C2H2_4 PF13894.6 AJW71543.1 - 0.04 14.7 1.7 3.5 8.7 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ACC PF17848.1 AJW71543.1 - 0.069 13.2 2.8 4.6 7.4 0.3 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Ribosomal_L32p PF01783.23 AJW71543.1 - 0.1 12.8 3.2 0.98 9.7 0.2 2.1 1 1 1 2 2 2 0 Ribosomal L32p protein family NRDD PF13597.6 AJW71543.1 - 0.12 11.2 0.6 0.14 11.0 0.6 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase zf-NADH-PPase PF09297.11 AJW71543.1 - 0.13 11.9 2.1 3.6 7.3 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.6 AJW71543.1 - 0.17 11.8 6.0 3.2 7.8 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 AJW71543.1 - 0.32 10.7 5.7 2.3 8.0 5.7 2.0 1 1 0 1 1 1 0 Rubredoxin metal binding domain YqhG PF11079.8 AJW71544.1 - 0.028 13.4 0.2 0.031 13.2 0.2 1.0 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function DUF2682 PF10909.8 AJW71544.1 - 0.094 13.2 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) Nipped-B_C PF12830.7 AJW71544.1 - 0.11 12.4 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus HTH_6 PF01418.17 AJW71544.1 - 0.12 12.4 0.4 5.8 7.0 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family KAR PF15222.6 AJW71544.1 - 0.15 12.4 0.1 0.51 10.7 0.1 1.7 2 0 0 2 2 2 0 Kidney androgen-regulated Cor1 PF04803.12 AJW71545.1 - 0.00029 21.0 3.1 0.0032 17.7 1.1 2.0 1 1 1 2 2 2 2 Cor1/Xlr/Xmr conserved region TPD52 PF04201.15 AJW71545.1 - 0.0026 17.4 1.2 0.0032 17.1 1.2 1.1 1 0 0 1 1 1 1 Tumour protein D52 family DUSP PF06337.12 AJW71545.1 - 0.085 13.5 0.4 0.19 12.4 0.4 1.7 1 1 0 1 1 1 0 DUSP domain DUF1059 PF06348.11 AJW71546.1 - 6.6e-06 26.3 0.0 8.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) AsnC_trans_reg PF01037.21 AJW71547.1 - 8.5e-19 67.3 0.3 1.2e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain NapD PF03927.13 AJW71547.1 - 0.00036 20.5 0.2 0.48 10.5 0.0 2.8 2 1 0 2 2 2 2 NapD protein GYD PF08734.11 AJW71547.1 - 0.00072 19.5 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 2 GYD domain FtsX_ECD PF18075.1 AJW71547.1 - 0.018 15.7 0.1 1.6 9.4 0.1 2.6 3 0 0 3 3 3 0 FtsX extracellular domain DUF2129 PF09902.9 AJW71547.1 - 0.025 14.6 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) DUF2209 PF09974.9 AJW71547.1 - 0.049 14.0 0.2 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) DUF1479 PF07350.12 AJW71547.1 - 0.071 11.9 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) HMA PF00403.26 AJW71547.1 - 0.22 12.0 3.0 2 8.9 0.9 3.0 2 2 1 3 3 3 0 Heavy-metal-associated domain zf-UBP_var PF17807.1 AJW71548.1 - 0.064 13.0 0.9 0.074 12.8 0.9 1.1 1 0 0 1 1 1 0 Variant UBP zinc finger CDC48_N PF02359.18 AJW71549.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain UPF0126 PF03458.13 AJW71550.1 - 6.8e-39 131.6 30.2 3.8e-21 74.8 8.9 2.4 3 0 0 3 3 3 2 UPF0126 domain Ribosomal_60s PF00428.19 AJW71551.1 - 1.7e-13 51.0 19.1 2e-13 50.7 19.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF5327 PF17261.2 AJW71551.1 - 0.091 13.5 0.5 0.12 13.1 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5327) HATPase_c PF02518.26 AJW71553.1 - 9e-21 74.5 0.1 2e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW71553.1 - 8e-07 29.0 0.2 1.9e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW71553.1 - 2.1e-06 27.6 0.1 9.1e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 AJW71553.1 - 3.6e-05 23.6 0.0 8.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AJW71553.1 - 0.00063 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF2779 PF11074.8 AJW71553.1 - 0.48 10.9 3.5 3.3 8.2 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) tRNA-synt_2c PF01411.19 AJW71554.1 - 1.6e-80 271.2 0.2 1.6e-80 271.2 0.2 1.9 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 AJW71554.1 - 1.3e-14 54.0 1.1 1.3e-14 54.0 1.1 2.3 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 AJW71554.1 - 1.2e-09 38.7 9.0 8.7e-09 35.9 9.0 2.4 1 1 0 1 1 1 1 DHHA1 domain YolD PF08863.10 AJW71554.1 - 0.017 15.2 0.1 0.017 15.2 0.1 2.4 2 0 0 2 2 2 0 YolD-like protein PVL_ORF50 PF07768.11 AJW71554.1 - 0.4 11.0 4.4 0.12 12.7 0.9 1.9 2 0 0 2 2 2 0 PVL ORF-50-like family tRNA-synt_1 PF00133.22 AJW71555.1 - 6.9e-60 202.9 1.0 5.3e-59 200.0 1.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AJW71555.1 - 3.7e-23 82.2 0.4 7.7e-23 81.1 0.4 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AJW71555.1 - 1.6e-22 79.8 0.2 2e-11 43.3 0.1 3.0 2 1 1 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AJW71555.1 - 4.6e-12 45.9 3.7 1.4e-07 31.2 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 AJW71555.1 - 3.1e-07 30.1 0.3 1.5e-06 27.8 0.0 2.2 2 1 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 UVR PF02151.19 AJW71558.1 - 0.0031 17.2 0.1 0.0089 15.7 0.1 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif Peripla_BP_2 PF01497.18 AJW71558.1 - 0.0056 16.3 0.1 0.0083 15.7 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein LMP PF04778.12 AJW71558.1 - 0.014 15.3 0.5 0.026 14.4 0.5 1.5 1 0 0 1 1 1 0 LMP repeated region T3SSipB PF16535.5 AJW71558.1 - 0.042 14.3 0.4 0.088 13.3 0.4 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB ABC_tran_CTD PF16326.5 AJW71558.1 - 0.059 13.6 3.1 0.069 13.4 1.6 2.0 2 1 0 2 2 2 0 ABC transporter C-terminal domain LUC7 PF03194.15 AJW71558.1 - 0.088 12.5 0.2 0.34 10.5 0.2 1.8 2 0 0 2 2 2 0 LUC7 N_terminus MtrG PF04210.13 AJW71558.1 - 0.2 11.5 1.0 3.1 7.7 0.7 2.6 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G zinc_ribbon_4 PF13717.6 AJW71559.1 - 0.0017 18.2 2.2 0.71 9.8 0.2 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 AJW71559.1 - 0.014 15.0 1.5 0.5 10.1 0.1 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PolC_DP2 PF03833.13 AJW71559.1 - 0.024 12.5 0.5 0.029 12.3 0.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 ADK_lid PF05191.14 AJW71559.1 - 0.038 14.0 0.9 4.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid HypA PF01155.19 AJW71559.1 - 0.041 13.9 0.1 0.046 13.8 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 AJW71559.1 - 0.092 12.5 2.3 5.5 6.8 2.3 2.2 1 1 0 1 1 1 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 AJW71559.1 - 0.11 12.0 4.3 4 7.0 0.7 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Wzy_C PF04932.15 AJW71559.1 - 0.13 11.9 5.0 0.12 12.0 5.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF3742 PF12553.8 AJW71559.1 - 0.15 12.2 2.5 0.16 12.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) zf-H2C2_2 PF13465.6 AJW71559.1 - 0.39 11.2 2.8 1.3 9.6 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Halogen_Hydrol PF10112.9 AJW71559.1 - 0.5 10.4 3.0 0.5 10.4 3.0 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YdfA_immunity PF12127.8 AJW71559.1 - 1 8.4 5.0 1.1 8.3 5.0 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial zf_UBZ PF18439.1 AJW71559.1 - 1.5 8.5 3.2 5 6.8 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 AJW71559.1 - 2.3 8.2 6.4 1.3 9.0 0.8 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Phage_holin_3_6 PF07332.11 AJW71559.1 - 2.3 8.3 9.3 2.6 8.1 9.3 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 AJW71559.1 - 2.6 6.7 6.4 2.7 6.7 6.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3099 PF11298.8 AJW71559.1 - 2.9 8.1 7.7 3.2 8.0 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) zf-C2H2 PF00096.26 AJW71559.1 - 4 8.1 5.7 5.2 7.7 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2244 PF10003.9 AJW71559.1 - 8.9 6.0 8.0 9.7 5.9 8.0 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Usp PF00582.26 AJW71561.1 - 5.2e-31 108.0 0.0 6e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Pro_Al_protease PF02983.14 AJW71561.1 - 0.00083 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-lytic protease prodomain CamS PF07537.11 AJW71561.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor MRP_L53 PF10780.9 AJW71561.1 - 0.061 13.5 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Usp PF00582.26 AJW71562.1 - 1.6e-26 93.5 0.0 1.8e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF4533 PF15047.6 AJW71562.1 - 0.039 13.5 2.8 0.051 13.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Tox-HDC PF15656.6 AJW71562.1 - 0.076 13.2 0.2 0.25 11.5 0.2 1.7 1 1 1 2 2 2 0 Toxin with a H, D/N and C signature HTH_3 PF01381.22 AJW71562.1 - 0.11 12.6 0.2 0.34 11.0 0.2 1.9 2 1 0 2 2 2 0 Helix-turn-helix Ig_4 PF16680.5 AJW71563.1 - 0.015 15.5 0.2 0.016 15.5 0.2 1.1 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain LEA_2 PF03168.13 AJW71564.1 - 0.0029 18.1 0.0 0.0081 16.7 0.0 1.7 2 0 0 2 2 2 1 Late embryogenesis abundant protein DUF4307 PF14155.6 AJW71564.1 - 0.012 15.4 0.4 0.02 14.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF350 PF03994.14 AJW71564.1 - 0.094 12.9 2.0 9.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) DUF2633 PF11119.8 AJW71564.1 - 0.15 12.0 2.5 0.39 10.6 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Response_reg PF00072.24 AJW71565.1 - 1.7e-22 79.7 0.3 2e-22 79.5 0.3 1.1 1 0 0 1 1 1 1 Response regulator receiver domain CoA_binding PF02629.19 AJW71565.1 - 0.045 14.4 0.1 0.065 13.9 0.1 1.4 1 0 0 1 1 1 0 CoA binding domain Rad50_zn_hook PF04423.14 AJW71566.1 - 0.11 12.3 0.8 0.11 12.3 0.8 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-IS66 PF13005.7 AJW71566.1 - 0.15 12.5 6.6 1.4 9.3 0.3 2.4 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_15 PF17032.5 AJW71566.1 - 0.45 11.3 7.8 0.63 10.8 7.8 1.2 1 0 0 1 1 1 0 zinc-ribbon family FAM76 PF16046.5 AJW71569.1 - 0.034 13.5 4.3 0.045 13.1 4.3 1.3 1 1 0 1 1 1 0 FAM76 protein PhnA_Zn_Ribbon PF08274.12 AJW71569.1 - 0.19 11.7 2.1 0.39 10.7 2.1 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Gin PF10764.9 AJW71569.1 - 0.43 10.6 4.7 1.7 8.7 4.7 2.0 1 1 0 1 1 1 0 Inhibitor of sigma-G Gin DUF948 PF06103.11 AJW71570.1 - 0.023 14.9 1.2 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nitroreductase PF00881.24 AJW71571.1 - 6.1e-36 124.0 0.0 9e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AJW71571.1 - 9.8e-12 44.9 0.2 1.7e-06 27.7 0.5 2.8 2 1 0 2 2 2 2 Putative TM nitroreductase Geminin PF07412.12 AJW71571.1 - 0.061 13.1 0.1 0.089 12.5 0.1 1.3 1 0 0 1 1 1 0 Geminin Trp_halogenase PF04820.14 AJW71572.1 - 3.2e-05 23.0 0.0 0.00011 21.2 0.0 1.7 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_2 PF03446.15 AJW71572.1 - 0.00073 19.7 0.1 0.0016 18.7 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 AJW71572.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Toprim_Crpt PF13342.6 AJW71572.1 - 0.067 13.2 0.5 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase 2-Hacid_dh_C PF02826.19 AJW71572.1 - 0.096 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CxxCxxCC PF03692.15 AJW71573.1 - 2.5e-08 34.5 0.7 8.7e-08 32.7 0.7 1.9 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Ribosomal_S7 PF00177.21 AJW71575.1 - 2.9e-34 117.8 0.8 4.3e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 AJW71576.1 - 1e-46 157.3 0.3 1.3e-46 156.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KH_2 PF07650.17 AJW71577.1 - 5.7e-19 67.7 4.0 1.2e-12 47.5 0.4 2.1 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 AJW71577.1 - 1.5e-11 44.0 0.8 0.00011 22.0 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 AJW71577.1 - 1e-08 35.1 4.0 2.5e-08 33.9 0.4 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.29 AJW71577.1 - 0.00011 21.9 0.8 0.0083 15.9 0.1 2.4 2 0 0 2 2 2 2 KH domain Ribosomal_L7Ae PF01248.26 AJW71578.1 - 4.8e-14 51.9 0.2 5.8e-14 51.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UPF0113 PF03657.13 AJW71578.1 - 0.035 14.4 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 UPF0113 PUA domain HCBP_related PF06594.11 AJW71579.1 - 0.043 13.8 0.5 2.1 8.3 0.1 3.0 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain LSM PF01423.22 AJW71580.1 - 2.7e-18 65.4 2.1 3.1e-18 65.2 2.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 AJW71580.1 - 0.082 13.1 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RNA_pol_Rpb1_1 PF04997.12 AJW71581.1 - 4.7e-93 311.9 0.0 1.3e-92 310.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AJW71581.1 - 1.4e-82 277.1 2.2 3.4e-82 275.9 2.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AJW71581.1 - 8.9e-73 244.0 0.0 1.5e-72 243.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AJW71581.1 - 6e-33 114.0 0.0 1.6e-32 112.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AJW71581.1 - 2.8e-24 85.2 1.2 6.2e-23 80.8 0.2 3.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb2_6 PF00562.28 AJW71582.1 - 2.9e-126 421.7 0.1 4.2e-126 421.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AJW71582.1 - 9.4e-48 162.4 0.0 1.4e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 AJW71582.1 - 3.4e-32 110.7 0.1 7.5e-32 109.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 AJW71582.1 - 1.3e-27 95.8 0.1 2.9e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 AJW71582.1 - 1.8e-24 86.4 0.0 5e-24 85.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 AJW71582.1 - 2.9e-19 69.1 0.2 6.5e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 AJW71582.1 - 1.8e-08 34.8 0.0 4.7e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FYVE_2 PF02318.16 AJW71582.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 AJW71582.1 - 0.18 11.7 1.5 0.59 10.1 1.5 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RecR PF02132.15 AJW71582.1 - 0.34 10.5 1.8 1.9 8.1 0.6 2.3 2 0 0 2 2 2 0 RecR protein Ribosomal_L37e PF01907.19 AJW71582.1 - 0.37 11.0 0.9 0.83 9.9 0.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e RNA_pol_Rpb5_C PF01191.19 AJW71583.1 - 4.9e-27 93.6 0.1 5.8e-27 93.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Big_1 PF02369.16 AJW71584.1 - 0.044 13.8 1.1 0.22 11.6 1.1 2.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) MG2 PF01835.19 AJW71584.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 MG2 domain MG2 PF01835.19 AJW71585.1 - 0.00051 20.5 0.7 0.41 11.1 0.1 2.4 2 1 0 2 2 2 2 MG2 domain FlgD_ig PF13860.6 AJW71585.1 - 0.11 12.4 4.4 0.27 11.1 0.5 3.1 2 2 0 2 2 2 0 FlgD Ig-like domain DUF4959 PF16323.5 AJW71585.1 - 0.23 11.8 2.2 3.2 8.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4959) CE2_N PF17996.1 AJW71586.1 - 0.14 12.1 0.3 0.78 9.8 0.3 2.1 1 1 0 1 1 1 0 Carbohydrate esterase 2 N-terminal He_PIG PF05345.12 AJW71586.1 - 0.23 11.7 5.6 0.35 11.1 0.0 3.1 3 0 0 3 3 3 0 Putative Ig domain Aminotran_5 PF00266.19 AJW71588.1 - 4.9e-87 292.3 0.1 6.3e-87 291.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AJW71588.1 - 1.9e-06 27.4 0.0 2.1e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AJW71588.1 - 5.4e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJW71588.1 - 6.3e-05 21.7 0.0 0.00012 20.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AJW71588.1 - 6.9e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 AJW71588.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.21 AJW71588.1 - 0.065 11.9 0.1 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-III QueC PF06508.13 AJW71589.1 - 1.6e-07 31.1 0.1 7.9e-07 28.8 0.1 2.1 1 1 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 AJW71589.1 - 5.9e-07 28.9 0.0 9.2e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 AJW71589.1 - 1e-06 28.7 0.0 5.8e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.21 AJW71589.1 - 2.2e-06 27.6 0.1 3.9e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 AJW71589.1 - 3.3e-06 26.1 0.1 0.00011 21.2 0.1 2.2 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 AJW71589.1 - 2.1e-05 24.2 0.0 4.2e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) DUF111 PF01969.17 AJW71590.1 - 1.5e-101 340.3 0.0 1.7e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 Ldh_1_N PF00056.23 AJW71591.1 - 2.7e-37 128.0 0.6 5.3e-37 127.1 0.6 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AJW71591.1 - 2.4e-28 99.2 0.1 3.9e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AIRC PF00731.20 AJW71592.1 - 1.3e-15 57.2 3.0 2.4e-15 56.4 2.4 1.6 2 0 0 2 2 2 1 AIR carboxylase NAD_kinase PF01513.21 AJW71592.1 - 0.0024 17.1 0.2 0.0056 15.9 0.2 1.8 1 1 1 2 2 2 1 ATP-NAD kinase PrpR_N PF06506.11 AJW71592.1 - 0.026 14.1 1.4 0.26 10.9 0.2 2.4 2 0 0 2 2 2 0 Propionate catabolism activator Hpr_kinase_N PF02603.16 AJW71592.1 - 0.04 14.0 1.5 2.3 8.3 0.3 2.2 2 0 0 2 2 2 0 HPr Serine kinase N terminus HTH_ParB PF17762.1 AJW71592.1 - 0.053 13.3 0.4 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 HTH domain found in ParB protein Radical_SAM PF04055.21 AJW71593.1 - 1.1e-13 51.9 0.0 2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AJW71593.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Trypan_PARP PF05887.11 AJW71595.1 - 8.3e-06 25.8 49.9 9.4e-06 25.6 48.8 1.6 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 AJW71595.1 - 1.4 8.4 11.2 2.1 7.9 11.2 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) MG2 PF01835.19 AJW71596.1 - 0.00016 22.0 0.0 0.0014 19.0 0.0 2.6 2 0 0 2 2 2 1 MG2 domain Zip PF02535.22 AJW71597.1 - 0.00019 20.8 16.0 0.00019 20.8 16.0 2.5 1 1 1 2 2 2 1 ZIP Zinc transporter PIRT PF15099.6 AJW71597.1 - 0.075 12.6 6.5 0.21 11.2 0.1 2.7 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Internalin_N PF12354.8 AJW71597.1 - 0.12 12.4 2.3 0.16 12.1 0.0 2.4 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal DUF2070 PF09843.9 AJW71597.1 - 8.3 4.6 18.2 0.16 10.3 8.6 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) Cu-oxidase_3 PF07732.15 AJW71598.1 - 6.8e-23 80.9 6.4 1.1e-19 70.5 0.6 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AJW71598.1 - 2.6e-20 72.6 8.5 2.7e-10 40.1 0.5 3.2 3 0 0 3 3 3 3 Multicopper oxidase EMP24_GP25L PF01105.24 AJW71599.1 - 0.051 13.5 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HTH_20 PF12840.7 AJW71600.1 - 0.063 13.3 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_9 PF08221.11 AJW71600.1 - 0.19 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Ribosomal_S13 PF00416.22 AJW71601.1 - 2.9e-39 134.4 0.1 3.5e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 S4 PF01479.25 AJW71602.1 - 6.7e-10 38.5 1.5 1.6e-09 37.4 0.0 2.3 3 0 0 3 3 3 1 S4 domain SIS PF01380.22 AJW71603.1 - 2.2e-50 169.9 2.6 6.1e-26 90.8 1.4 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AJW71603.1 - 2.4e-21 76.3 0.0 4.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AJW71603.1 - 1.3e-17 63.8 0.1 4e-17 62.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS_2 PF13580.6 AJW71603.1 - 1.9e-08 34.4 1.0 0.00059 19.9 0.3 3.9 3 1 1 4 4 4 2 SIS domain GATase_4 PF13230.6 AJW71603.1 - 6.7e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Asparaginase_2 PF01112.18 AJW71603.1 - 0.016 14.3 0.0 1.2 8.1 0.0 2.6 2 1 0 2 2 2 0 Asparaginase Succ_DH_flav_C PF02910.20 AJW71603.1 - 0.094 12.7 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term DBI_PRT PF02277.17 AJW71604.1 - 9.8e-10 38.2 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyltransferase Lactamase_B PF00753.27 AJW71605.1 - 9e-21 74.8 0.5 1.2e-18 67.8 0.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AJW71605.1 - 3.4e-05 23.5 0.1 5.1e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain KAR PF15222.6 AJW71605.1 - 0.013 15.8 0.0 0.072 13.4 0.0 1.9 2 0 0 2 2 2 0 Kidney androgen-regulated YjeF_N PF03853.15 AJW71606.1 - 9.1e-46 155.9 0.0 1.1e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus fn3 PF00041.21 AJW71608.1 - 0.00082 19.7 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Translin PF01997.16 AJW71609.1 - 1e-11 45.2 1.1 3.6e-10 40.2 1.1 2.3 1 1 0 1 1 1 1 Translin family Ribonuc_red_lgN PF00317.21 AJW71609.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain RNA_pol_N PF01194.17 AJW71610.1 - 1e-27 96.2 0.4 1.3e-27 95.8 0.4 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Enolase_C PF00113.22 AJW71611.1 - 3.1e-55 187.5 0.1 5.4e-55 186.7 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AJW71611.1 - 4.1e-21 75.5 0.1 1.2e-20 74.0 0.1 1.8 1 1 0 1 1 1 1 Enolase, N-terminal domain Ribosomal_S2 PF00318.20 AJW71612.1 - 1.8e-21 76.4 0.7 6e-11 42.0 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein S2 AP_endonuc_2 PF01261.24 AJW71612.1 - 0.023 14.1 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel GHMP_kinases_N PF00288.26 AJW71613.1 - 5.9e-18 64.9 0.3 1.3e-17 63.8 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AJW71613.1 - 2.1e-14 53.6 0.0 4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 AJW71613.1 - 0.00021 20.8 0.0 0.00041 19.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF695 PF05117.12 AJW71613.1 - 0.0039 17.4 0.5 0.92 9.7 0.0 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF695) AA_kinase PF00696.28 AJW71614.1 - 9.4e-29 100.7 0.0 1.1e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF1967 PF09269.11 AJW71614.1 - 0.063 13.2 0.1 0.73 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) NUDIX PF00293.28 AJW71615.1 - 4.3e-14 52.7 0.0 5.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain polyprenyl_synt PF00348.17 AJW71616.1 - 4.6e-68 229.0 0.0 5.7e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3858 PF12970.7 AJW71616.1 - 0.044 13.8 0.5 0.09 12.8 0.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) tRNA-synt_1c PF00749.21 AJW71617.1 - 6.8e-77 258.4 0.0 9.5e-77 258.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AJW71617.1 - 1.8e-25 89.8 2.6 5.1e-25 88.3 0.2 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain FAA_hydrolase PF01557.18 AJW71618.1 - 3.4e-69 232.9 0.0 4.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 AJW71618.1 - 0.0099 16.7 0.0 0.024 15.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) Acetyltransf_1 PF00583.25 AJW71619.1 - 6.6e-06 26.3 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AJW71619.1 - 0.0018 18.7 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJW71619.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 AJW71619.1 - 0.094 13.0 0.1 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_CG PF14542.6 AJW71619.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Rieske PF00355.26 AJW71620.1 - 2.3e-20 72.3 0.0 2.9e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AJW71620.1 - 1.6e-09 37.6 0.0 1.9e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0147 PF03685.13 AJW71621.1 - 1.4e-30 105.2 1.9 1.6e-30 105.0 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) UPF0253 PF06786.12 AJW71621.1 - 0.014 15.7 0.1 3 8.2 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0253) PPDK_N PF01326.19 AJW71621.1 - 0.024 13.9 0.5 0.029 13.7 0.4 1.3 1 1 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain UvrB PF12344.8 AJW71621.1 - 0.054 13.3 1.7 3.6 7.5 0.2 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B Methyltransf_31 PF13847.6 AJW71622.1 - 2.4e-05 24.2 0.1 4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW71622.1 - 6.8e-05 23.5 0.0 0.00014 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 AJW71622.1 - 0.00035 20.2 1.2 0.019 14.5 0.5 2.5 2 1 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 AJW71622.1 - 0.00069 20.2 0.0 0.0017 18.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CUB PF00431.20 AJW71622.1 - 0.0066 16.8 0.4 3.4 8.0 0.0 2.2 2 0 0 2 2 2 2 CUB domain Methyltransf_18 PF12847.7 AJW71622.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AJW71622.1 - 0.1 12.1 0.2 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain CorA PF01544.18 AJW71624.1 - 3.9e-70 236.4 0.6 4.6e-70 236.2 0.6 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MIP-T3_C PF17749.1 AJW71624.1 - 0.026 14.5 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region HMMR_N PF15905.5 AJW71624.1 - 0.032 13.7 0.6 0.047 13.2 0.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3566 PF12089.8 AJW71624.1 - 0.076 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) DUF2397 PF09660.10 AJW71624.1 - 0.25 10.2 0.8 0.35 9.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3602 PF12223.8 AJW71625.1 - 0.028 15.0 4.7 0.048 14.3 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) TAL_FSA PF00923.19 AJW71626.1 - 4.3e-61 206.8 0.0 2.3e-60 204.4 0.0 1.9 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Transket_pyr PF02779.24 AJW71627.1 - 5.2e-31 107.7 0.0 7.9e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AJW71627.1 - 1.7e-30 105.5 0.0 2.7e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AJW71627.1 - 0.0064 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Ribul_P_3_epim PF00834.19 AJW71628.1 - 3.3e-51 173.5 0.3 5e-51 172.9 0.3 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Transketolase_N PF00456.21 AJW71628.1 - 4.2e-50 170.6 0.4 9.2e-49 166.2 0.4 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AJW71628.1 - 8.4e-06 25.2 0.1 0.0001 21.6 0.1 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 AJW71628.1 - 9.4e-06 24.8 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AJW71628.1 - 1.8e-05 24.5 0.1 4.3e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 AJW71628.1 - 0.00024 20.0 0.8 0.0027 16.6 0.1 2.3 2 0 0 2 2 2 1 XFP N-terminal domain DUF393 PF04134.12 AJW71629.1 - 0.00096 20.5 0.0 0.0013 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Isy1 PF06246.12 AJW71629.1 - 0.16 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Peptidase_M17 PF00883.21 AJW71630.1 - 1.4e-119 399.0 0.1 1.9e-119 398.6 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AJW71630.1 - 7.7e-18 64.6 0.1 1.9e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain zf-C2H2_4 PF13894.6 AJW71631.1 - 0.065 14.1 0.3 0.085 13.7 0.3 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger ABC_tran PF00005.27 AJW71632.1 - 1.3e-39 135.9 1.4 1.8e-18 67.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 AJW71632.1 - 4.6e-10 39.1 1.3 4.6e-10 39.1 1.3 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 AJW71632.1 - 3.8e-09 36.0 12.1 9.6e-09 34.7 6.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.19 AJW71632.1 - 8.2e-09 35.2 6.3 0.00032 20.2 0.4 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4_6 PF12837.7 AJW71632.1 - 1.3e-08 34.5 13.9 5.7e-07 29.3 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AJW71632.1 - 1.4e-06 28.1 1.8 1.4e-06 28.1 1.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 AJW71632.1 - 8.8e-06 25.8 13.4 1.5e-05 25.0 13.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJW71632.1 - 1.4e-05 25.1 12.4 4.3e-05 23.6 1.3 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 AJW71632.1 - 1.4e-05 25.0 0.8 0.028 14.3 0.0 3.8 4 0 0 4 4 4 1 RsgA GTPase Fer4_7 PF12838.7 AJW71632.1 - 8.6e-05 23.1 10.9 0.0015 19.0 12.2 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_29 PF13555.6 AJW71632.1 - 0.0081 15.9 0.8 0.64 9.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AJW71632.1 - 0.0084 16.2 1.3 0.23 11.6 0.4 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Fer4_16 PF13484.6 AJW71632.1 - 0.0086 17.0 1.4 0.0086 17.0 1.4 2.6 1 1 2 3 3 3 2 4Fe-4S double cluster binding domain AAA_16 PF13191.6 AJW71632.1 - 0.015 15.7 0.1 0.33 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 AJW71632.1 - 0.018 15.0 0.1 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 AJW71632.1 - 0.02 15.1 0.1 12 6.2 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 AJW71632.1 - 0.02 14.7 7.7 8.5 6.1 0.8 4.4 3 2 1 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system Fer4_4 PF12800.7 AJW71632.1 - 0.024 15.1 1.6 0.024 15.1 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 AJW71632.1 - 0.024 14.8 11.3 0.087 13.0 11.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain RE_XcyI PF09571.10 AJW71632.1 - 0.028 13.7 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 XcyI restriction endonuclease RuvB_N PF05496.12 AJW71632.1 - 0.028 14.2 0.1 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 AJW71632.1 - 0.032 14.3 0.1 4.6 7.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 AJW71632.1 - 0.033 13.9 3.5 4.4 6.9 0.1 2.9 2 2 0 2 2 2 0 AAA ATPase domain Fer4_3 PF12798.7 AJW71632.1 - 0.033 15.1 4.9 0.033 15.1 4.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain NB-ARC PF00931.22 AJW71632.1 - 0.055 12.7 0.6 3.6 6.7 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain DLIC PF05783.11 AJW71632.1 - 0.082 11.7 0.7 0.64 8.8 0.1 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 AJW71632.1 - 0.11 13.0 0.5 2.6 8.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Fer4_17 PF13534.6 AJW71632.1 - 2.2 8.9 9.4 0.39 11.3 1.5 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJW71632.1 - 4.9 7.7 9.5 0.47 10.9 1.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Phage_holin_3_6 PF07332.11 AJW71633.1 - 0.0082 16.2 0.9 0.01 15.9 0.9 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III HlyIII PF03006.20 AJW71633.1 - 0.27 10.9 4.3 0.32 10.7 4.3 1.0 1 0 0 1 1 1 0 Haemolysin-III related DUF2207 PF09972.9 AJW71633.1 - 0.62 8.8 3.2 0.7 8.6 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Acetyltransf_1 PF00583.25 AJW71634.1 - 1.1e-18 67.5 0.2 1.4e-18 67.2 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AJW71634.1 - 8.1e-14 51.8 1.4 9.3e-14 51.6 0.5 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJW71634.1 - 1.7e-12 47.4 0.2 2.5e-12 46.8 0.2 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJW71634.1 - 9.2e-09 35.2 0.1 4.3e-08 33.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 AJW71634.1 - 0.00092 18.9 0.0 0.0032 17.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AJW71634.1 - 0.0051 16.4 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 AJW71634.1 - 0.0096 16.0 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AJW71634.1 - 0.015 16.0 0.0 0.02 15.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4821 PF16092.5 AJW71634.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Acetyltransf_4 PF13420.7 AJW71634.1 - 0.04 14.0 0.4 0.064 13.4 0.4 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M50 PF02163.22 AJW71635.1 - 1e-11 44.6 13.8 1.2e-07 31.3 0.8 2.6 1 1 1 2 2 2 2 Peptidase family M50 DUF3698 PF12479.8 AJW71635.1 - 0.00013 22.5 0.1 0.00024 21.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3698) DDOST_48kD PF03345.14 AJW71635.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Pribosyltran PF00156.27 AJW71637.1 - 1.6e-16 60.3 0.6 2.2e-16 59.8 0.6 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AJW71637.1 - 0.00035 20.1 0.1 0.00066 19.2 0.1 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.6 AJW71637.1 - 0.00042 19.8 0.1 0.00054 19.5 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TENA_THI-4 PF03070.16 AJW71638.1 - 7.3e-15 55.3 0.2 8.4e-15 55.1 0.2 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 AJW71638.1 - 3.3e-13 49.8 0.0 4.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme DUF2812 PF11193.8 AJW71638.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) DUF2153 PF09921.9 AJW71638.1 - 0.14 12.0 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) polyprenyl_synt PF00348.17 AJW71639.1 - 9.9e-48 162.4 0.0 1.3e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Proton_antipo_M PF00361.20 AJW71640.1 - 1.7e-68 231.0 27.0 1.7e-68 231.0 27.0 2.4 2 1 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_M PF00361.20 AJW71641.1 - 1.3e-58 198.5 36.6 5.1e-58 196.6 29.7 3.1 2 1 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AJW71641.1 - 2e-13 50.2 2.2 2e-13 50.2 2.2 3.3 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 AJW71641.1 - 0.025 14.2 0.2 0.069 12.8 0.1 1.6 1 1 1 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus PsbW PF07123.12 AJW71641.1 - 0.03 14.3 1.7 0.098 12.7 0.7 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Proton_antipo_M PF00361.20 AJW71642.1 - 1.5e-61 208.2 24.1 1.5e-61 208.2 24.1 1.8 1 1 1 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AJW71642.1 - 0.00023 21.2 2.9 0.00047 20.2 0.0 3.0 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.24 AJW71643.1 - 4.3e-22 77.7 5.9 5.7e-22 77.3 5.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L VPDSG-CTERM PF18205.1 AJW71643.1 - 0.45 10.4 6.4 2.6 7.9 0.1 2.8 3 0 0 3 3 3 0 VPDSG-CTERM motif PEP-CTERM PF07589.11 AJW71643.1 - 2.2 8.5 3.8 12 6.2 0.1 2.6 2 1 0 2 2 2 0 PEP-CTERM motif Oxidored_q3 PF00499.20 AJW71644.1 - 2.1e-23 82.7 10.1 2.1e-23 82.7 10.1 1.3 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Fer4 PF00037.27 AJW71645.1 - 7.8e-12 44.5 10.8 3.2e-09 36.2 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AJW71645.1 - 7.2e-09 35.6 18.3 1.8e-05 24.7 11.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJW71645.1 - 9.3e-09 35.8 9.2 1.5e-08 35.1 9.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJW71645.1 - 2.8e-08 33.8 20.3 4.9e-06 26.6 10.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJW71645.1 - 2.2e-07 31.0 6.7 3.9e-07 30.1 6.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJW71645.1 - 1.9e-06 28.2 2.4 0.0045 17.4 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AJW71645.1 - 9.6e-06 25.4 9.8 0.0016 18.4 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AJW71645.1 - 2e-05 24.5 11.8 4.3e-05 23.4 1.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 AJW71645.1 - 8e-05 22.8 7.9 0.012 16.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AJW71645.1 - 0.0011 19.9 9.8 0.0051 17.7 0.2 2.4 1 1 2 3 3 3 2 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 AJW71645.1 - 0.0014 19.3 4.6 0.23 12.2 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_17 PF13534.6 AJW71645.1 - 0.0017 18.8 10.7 0.028 14.9 0.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 AJW71645.1 - 0.0038 17.8 4.1 0.22 12.1 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AJW71645.1 - 0.011 16.6 4.1 0.011 16.6 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AJW71645.1 - 0.11 12.6 9.0 0.14 12.3 1.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AJW71645.1 - 2.7 8.9 11.3 0.7 10.8 0.9 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain NADHdh PF00146.21 AJW71646.1 - 4.6e-94 315.1 23.3 4.6e-94 315.1 23.3 1.4 2 0 0 2 2 2 1 NADH dehydrogenase NDUF_B12 PF08122.12 AJW71646.1 - 0.043 13.9 1.1 0.043 13.9 1.1 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Oxidored_q6 PF01058.22 AJW71647.1 - 5.1e-25 87.8 0.1 7.1e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.19 AJW71648.1 - 1.9e-18 66.4 1.3 2.3e-18 66.1 0.6 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3697 PF12478.8 AJW71648.1 - 0.13 12.4 0.2 0.22 11.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 AhpC-TSA PF00578.21 AJW71649.1 - 1.7e-32 111.9 0.0 2e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AJW71649.1 - 6.4e-22 77.8 0.0 7.4e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 AJW71649.1 - 0.0037 17.2 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA_2 PF13911.6 AJW71649.1 - 0.0059 16.7 0.0 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Biotin_lipoyl PF00364.22 AJW71650.1 - 3.2e-18 65.3 5.1 3.2e-18 65.3 5.1 1.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AJW71650.1 - 1.3e-14 53.8 2.4 3.6e-09 36.3 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AJW71650.1 - 9.5e-06 25.0 0.6 0.11 11.7 0.0 2.9 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AJW71650.1 - 3e-05 24.7 0.4 0.25 12.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 AJW71650.1 - 0.00024 21.0 1.4 0.00047 20.1 1.4 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 AJW71650.1 - 0.00077 19.4 1.2 0.0011 18.9 0.4 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M23 PF01551.22 AJW71650.1 - 0.0046 17.1 1.1 0.49 10.6 0.1 2.7 2 1 1 3 3 3 1 Peptidase family M23 QRPTase_N PF02749.16 AJW71650.1 - 0.0057 16.7 0.2 0.098 12.7 0.0 2.2 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 AJW71650.1 - 0.022 14.6 2.8 0.031 14.2 1.6 1.9 2 1 0 2 2 2 0 Glycine cleavage H-protein PYNP_C PF07831.13 AJW71650.1 - 0.05 13.3 0.2 0.52 10.0 0.1 2.2 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain eIF-1a PF01176.19 AJW71650.1 - 0.076 12.8 0.3 0.75 9.6 0.0 2.4 2 1 1 3 3 3 0 Translation initiation factor 1A / IF-1 CPSase_L_D2 PF02786.17 AJW71651.1 - 3.1e-71 239.2 0.1 4.8e-71 238.6 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AJW71651.1 - 9.8e-47 158.1 0.0 2.4e-46 156.8 0.0 1.7 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AJW71651.1 - 4e-33 113.8 0.0 7.7e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 AJW71651.1 - 1.5e-11 44.2 0.1 3.2e-11 43.1 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AJW71651.1 - 2.4e-09 37.0 0.4 5.5e-09 35.9 0.4 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AJW71651.1 - 7.5e-08 32.6 0.1 1.4e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AJW71651.1 - 2.8e-07 30.3 0.1 7.8e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AJW71651.1 - 4.4e-05 23.1 0.2 0.00011 21.8 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AJW71651.1 - 0.02 14.2 0.1 0.053 12.8 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF3182 PF11379.8 AJW71651.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) ATPgrasp_Ter PF15632.6 AJW71651.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 AJW71651.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Carboxyl_trans PF01039.22 AJW71652.1 - 3e-185 616.6 0.1 3.4e-185 616.4 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AJW71652.1 - 1.3e-06 28.0 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) AAA PF00004.29 AJW71654.1 - 8.6e-13 48.9 0.0 2.2e-12 47.5 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AJW71654.1 - 1.9e-07 31.0 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 AJW71654.1 - 2.5e-06 27.6 0.3 8.9e-06 25.7 0.0 2.0 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 AJW71654.1 - 2.4e-05 24.8 0.0 4.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 AJW71654.1 - 9.7e-05 21.7 0.0 0.00024 20.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 AJW71654.1 - 0.00072 19.6 0.0 0.0029 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 AJW71654.1 - 0.0015 18.6 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 AJW71654.1 - 0.0026 17.3 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 AJW71654.1 - 0.0048 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AJW71654.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.14 AJW71654.1 - 0.0053 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AJW71654.1 - 0.0066 15.8 0.1 0.023 14.1 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AJW71654.1 - 0.0072 16.5 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AJW71654.1 - 0.011 16.0 0.0 0.078 13.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 AJW71654.1 - 0.015 15.1 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 AJW71654.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 AJW71654.1 - 0.016 15.6 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AJW71654.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AJW71654.1 - 0.026 14.9 0.0 0.074 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 AJW71654.1 - 0.031 14.0 0.1 0.083 12.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 AJW71654.1 - 0.034 13.5 0.0 2 7.8 0.0 2.8 2 1 1 3 3 3 0 Bacterial TniB protein ABC_tran PF00005.27 AJW71654.1 - 0.038 14.5 0.1 0.21 12.1 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 AJW71654.1 - 0.039 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AJW71654.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 AJW71654.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 AJW71654.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AJW71654.1 - 0.24 11.1 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Inositol_P PF00459.25 AJW71656.1 - 3.2e-27 95.7 0.0 3.8e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AJW71656.1 - 0.00074 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NAD_binding_1 PF00175.21 AJW71657.1 - 7e-11 42.7 0.0 1.4e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AJW71657.1 - 3.1e-09 37.1 0.0 5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Methyltransf_34 PF11312.8 AJW71657.1 - 0.0067 15.7 0.0 0.0086 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase NAD_binding_6 PF08030.12 AJW71657.1 - 0.039 14.1 0.0 0.058 13.5 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain DUF1059 PF06348.11 AJW71658.1 - 3e-06 27.4 0.2 3.4e-06 27.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) GlutR_N PF05201.15 AJW71659.1 - 2.7e-25 88.8 0.0 4.2e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AJW71659.1 - 1.4e-18 67.2 0.0 4.8e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AJW71659.1 - 0.0022 18.5 0.0 0.0042 17.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ABC_tran_Xtn PF12848.7 AJW71660.1 - 0.032 14.3 0.1 0.032 14.3 0.1 3.2 2 1 2 4 4 4 0 ABC transporter DivIVA PF05103.13 AJW71660.1 - 0.13 12.4 0.2 0.13 12.4 0.2 3.2 2 1 1 3 3 3 0 DivIVA protein Lyase_1 PF00206.20 AJW71661.1 - 3.5e-51 174.5 0.0 2.2e-50 171.8 0.0 2.0 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 AJW71661.1 - 3.5e-13 50.1 0.0 2e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal FeS_assembly_P PF01883.19 AJW71662.1 - 7.5e-17 61.3 0.2 1.1e-16 60.8 0.2 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Fer2_3 PF13085.6 AJW71663.1 - 1.2e-31 109.0 0.0 2.3e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 AJW71663.1 - 1.7e-11 44.4 4.6 2.1e-11 44.1 2.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJW71663.1 - 5.5e-10 39.2 2.5 5.5e-10 39.2 2.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AJW71663.1 - 4e-09 36.9 13.5 2e-07 31.5 4.0 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AJW71663.1 - 7.3e-09 36.0 11.9 1.4e-07 31.9 2.5 2.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJW71663.1 - 1.7e-07 31.3 2.2 1.7e-07 31.3 2.2 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJW71663.1 - 3.7e-07 31.0 2.4 3.7e-07 31.0 2.4 2.2 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 AJW71663.1 - 0.00011 22.4 8.1 0.033 14.4 0.4 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 AJW71663.1 - 0.00015 21.7 1.1 0.00027 20.8 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AJW71663.1 - 0.00016 21.4 1.7 0.00016 21.4 1.7 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 AJW71663.1 - 0.019 15.0 4.1 0.019 15.0 4.1 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 AJW71663.1 - 0.019 15.0 1.9 0.019 15.0 1.9 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 AJW71663.1 - 0.88 10.7 21.4 0.38 11.8 4.6 3.2 3 1 0 3 3 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 AJW71663.1 - 0.93 9.7 16.1 0.17 12.1 8.4 3.0 2 2 1 3 3 3 0 4Fe-4S dicluster domain Sdh_cyt PF01127.22 AJW71664.1 - 3e-07 30.5 3.5 3.7e-07 30.2 3.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AJW71664.1 - 0.05 13.7 2.6 0.07 13.2 2.6 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit D Sdh_cyt PF01127.22 AJW71665.1 - 4.9e-09 36.3 3.4 7.1e-09 35.7 2.9 1.5 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AJW71665.1 - 0.017 15.2 4.2 0.062 13.4 0.1 2.2 2 0 0 2 2 2 0 Fumarate reductase subunit D Fumarate_red_C PF02300.17 AJW71665.1 - 1.1 9.3 4.2 0.36 10.9 0.8 1.7 2 0 0 2 2 2 0 Fumarate reductase subunit C FAD_binding_2 PF00890.24 AJW71666.1 - 1.4e-97 327.5 0.1 1.8e-97 327.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AJW71666.1 - 7e-36 123.0 1.4 1.1e-35 122.4 1.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AJW71666.1 - 2e-07 30.6 0.0 0.00021 20.6 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AJW71666.1 - 0.0015 17.9 1.1 0.021 14.2 0.4 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 AJW71666.1 - 0.0018 17.6 1.1 0.0049 16.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 AJW71666.1 - 0.0019 17.4 0.1 0.072 12.2 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 AJW71666.1 - 0.02 13.6 0.1 1.3 7.6 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 AJW71666.1 - 0.061 12.9 0.3 0.48 9.9 0.1 2.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AJW71666.1 - 0.12 11.4 0.5 0.23 10.5 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein PadR PF03551.14 AJW71667.1 - 1.5e-11 44.1 0.1 2.9e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 AJW71667.1 - 7.4e-05 22.7 0.1 7.4e-05 22.7 0.1 2.2 3 1 0 3 3 3 1 Winged helix-turn-helix Mrr_N PF14338.6 AJW71667.1 - 0.00044 20.3 0.4 0.029 14.5 0.1 2.6 3 0 0 3 3 3 1 Mrr N-terminal domain RTP PF02334.16 AJW71667.1 - 0.00083 20.0 1.3 0.012 16.2 0.0 2.3 1 1 1 2 2 2 1 Replication terminator protein DUF1451 PF07295.11 AJW71667.1 - 0.05 13.6 1.3 0.8 9.7 0.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain Hemocyanin_M PF00372.19 AJW71667.1 - 0.12 11.6 0.3 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Stork_head PF10264.9 AJW71667.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Lactamase_B PF00753.27 AJW71668.1 - 1.6e-10 41.3 3.0 2.2e-10 40.9 3.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PEP_mutase PF13714.6 AJW71669.1 - 1.4e-50 172.0 0.0 1.6e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 AJW71669.1 - 3.3e-15 55.6 0.0 4.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 AJW71669.1 - 0.026 13.9 0.1 0.19 11.1 0.0 2.3 2 1 1 3 3 3 0 Ketopantoate hydroxymethyltransferase Alba PF01918.21 AJW71670.1 - 1.2e-11 44.3 0.1 1.9e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 AJW71670.1 - 0.069 13.1 0.5 4.2 7.3 0.0 2.1 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P HEAT_2 PF13646.6 AJW71671.1 - 4.1e-14 52.7 0.0 2.7e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 AJW71671.1 - 5.2e-11 41.8 0.0 0.021 15.0 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 AJW71671.1 - 5.4e-08 33.2 0.0 0.098 13.2 0.0 4.1 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 AJW71671.1 - 0.00091 19.3 1.7 0.3 11.1 0.1 3.2 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 AJW71671.1 - 0.0012 19.1 0.2 2.3 8.6 0.1 2.8 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion V-ATPase_H_C PF11698.8 AJW71671.1 - 0.12 12.5 1.2 1.2 9.3 0.2 2.7 1 1 2 3 3 3 0 V-ATPase subunit H NAD_binding_1 PF00175.21 AJW71672.1 - 2.9e-13 50.4 0.0 5.3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AJW71672.1 - 1.2e-07 32.0 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Methyltransf_34 PF11312.8 AJW71672.1 - 0.052 12.8 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase NAD_binding_6 PF08030.12 AJW71672.1 - 0.17 12.0 0.2 0.67 10.1 0.1 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain CTP_transf_like PF01467.26 AJW71673.1 - 0.0072 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Aminotran_4 PF01063.19 AJW71674.1 - 1.1e-45 156.2 0.0 1.3e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV DUF22 PF01629.16 AJW71674.1 - 0.044 13.5 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 GFO_IDH_MocA PF01408.22 AJW71675.1 - 9e-25 87.8 0.0 1.7e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AJW71675.1 - 2.2e-07 30.9 0.1 5.5e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 AJW71675.1 - 0.0066 15.8 0.1 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trm112p PF03966.16 AJW71676.1 - 8.9e-09 35.8 0.2 2.6e-08 34.3 0.2 1.8 1 1 0 1 1 1 1 Trm112p-like protein Hexapep PF00132.24 AJW71677.1 - 2.4e-26 90.4 17.0 4.3e-11 42.1 1.3 4.9 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJW71677.1 - 5e-17 61.4 15.3 8.2e-11 41.5 2.5 4.4 4 1 1 5 5 5 4 Hexapeptide repeat of succinyl-transferase CHASE2 PF05226.11 AJW71677.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 CHASE2 domain Urease_alpha PF00449.20 AJW71677.1 - 0.62 10.4 5.5 1.5 9.1 5.5 1.8 1 1 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Saf_2TM PF18303.1 AJW71678.1 - 0.046 13.3 8.1 0.062 12.9 8.1 1.3 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain Glycos_transf_4 PF00953.21 AJW71679.1 - 4.4e-27 95.0 16.4 4.4e-27 95.0 16.4 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 DEAD PF00270.29 AJW71680.1 - 9e-27 94.0 0.1 1.5e-25 89.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AJW71680.1 - 2.7e-11 43.8 0.0 5.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AJW71680.1 - 4.5e-11 43.1 1.7 1.5e-09 38.2 0.1 3.5 3 1 0 3 3 3 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 AJW71680.1 - 2.6e-10 40.7 1.2 8.6e-10 39.1 1.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 AJW71680.1 - 4.9e-06 26.5 0.4 3.5e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 AJW71680.1 - 3.3e-05 23.6 0.0 9.7e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda ATPase_2 PF01637.18 AJW71680.1 - 0.0027 17.7 0.2 0.0027 17.7 0.2 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AJW71680.1 - 0.024 14.2 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AJW71680.1 - 0.055 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DnaB_C PF03796.15 AJW71680.1 - 0.091 12.1 0.3 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HHH_8 PF14716.6 AJW71680.1 - 0.14 12.6 0.7 2 8.8 0.7 2.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain MCM PF00493.23 AJW71681.1 - 1.9e-91 305.1 0.0 2.9e-91 304.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 AJW71681.1 - 3.4e-35 120.6 0.1 6.1e-35 119.8 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 AJW71681.1 - 3.6e-23 81.8 0.8 7.1e-23 80.8 0.8 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 AJW71681.1 - 4.3e-11 43.3 0.5 1.5e-10 41.6 0.5 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 AJW71681.1 - 3.6e-06 26.5 0.0 0.00026 20.4 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AJW71681.1 - 7.7e-06 26.0 0.1 0.00023 21.2 0.0 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AJW71681.1 - 0.0015 18.4 0.0 0.0048 16.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sld5 PF05916.11 AJW71682.1 - 9.9e-09 35.6 0.6 1.4e-08 35.2 0.6 1.2 1 0 0 1 1 1 1 GINS complex protein DUF620 PF04788.12 AJW71682.1 - 0.018 14.5 0.2 0.029 13.8 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF620) PYRIN PF02758.16 AJW71682.1 - 0.024 14.8 1.1 0.046 13.9 1.1 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain DNA_pol3_delta2 PF13177.6 AJW71683.1 - 1.5e-15 57.4 0.1 3e-12 46.6 0.1 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 AJW71683.1 - 7e-13 49.2 0.6 2.9e-12 47.1 0.2 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 AJW71683.1 - 3.4e-11 43.4 1.6 5.8e-11 42.6 0.7 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 AJW71683.1 - 3e-07 30.4 0.1 7.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 AJW71683.1 - 2.1e-05 24.3 0.0 8.6e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AJW71683.1 - 0.00025 21.5 0.0 0.2 12.0 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 AJW71683.1 - 0.00026 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AJW71683.1 - 0.00029 20.8 0.0 0.0038 17.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 AJW71683.1 - 0.00087 19.6 0.1 0.0023 18.3 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 AJW71683.1 - 0.0012 19.2 0.5 1 9.6 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.6 AJW71683.1 - 0.0019 18.0 0.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AJW71683.1 - 0.007 15.8 0.0 0.65 9.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein DEAD PF00270.29 AJW71683.1 - 0.011 15.5 0.9 1.3 8.8 0.1 2.5 1 1 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 AJW71683.1 - 0.022 14.2 0.1 2.9 7.2 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PTPlike_phytase PF14566.6 AJW71683.1 - 0.031 14.4 0.1 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Viral_helicase1 PF01443.18 AJW71683.1 - 0.043 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 AJW71683.1 - 0.045 13.2 0.1 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 AJW71683.1 - 0.096 12.7 0.1 4.5 7.3 0.0 2.4 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 AJW71683.1 - 0.16 12.6 1.1 0.58 10.7 0.4 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AJW71683.1 - 0.16 11.9 0.4 1.6 8.8 0.4 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Fer4_7 PF12838.7 AJW71684.1 - 7.6e-10 39.2 1.3 0.00036 21.1 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AJW71684.1 - 3.5e-09 36.1 9.6 0.00012 21.7 3.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AJW71684.1 - 1.2e-08 35.7 14.8 2.5e-06 28.3 5.0 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AJW71684.1 - 4.8e-08 33.0 5.3 0.0017 18.4 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJW71684.1 - 2.6e-07 31.0 13.6 2.3e-06 27.9 7.1 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJW71684.1 - 3.2e-07 30.3 7.3 7.3e-06 26.0 8.3 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AJW71684.1 - 2e-06 27.8 7.8 1.9e-05 24.7 8.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJW71684.1 - 3.3e-06 26.9 10.9 0.004 17.2 4.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AJW71684.1 - 3.3e-05 24.4 3.6 0.00014 22.3 4.3 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AJW71684.1 - 0.00027 20.9 10.8 0.0063 16.5 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AJW71684.1 - 0.0021 18.4 7.7 0.39 11.3 0.2 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AJW71684.1 - 0.0029 17.8 8.0 0.022 15.0 5.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AJW71684.1 - 0.01 16.3 9.4 0.76 10.4 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AJW71684.1 - 0.013 16.4 1.3 2.9 8.8 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AJW71684.1 - 0.05 14.3 5.4 0.72 10.6 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 AJW71684.1 - 0.3 12.1 15.4 1.6 9.9 5.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 AJW71685.1 - 7.3e-10 38.2 11.9 5.9e-06 25.9 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AJW71685.1 - 1.1e-09 38.7 4.5 6.2e-05 23.5 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AJW71685.1 - 2.5e-07 30.7 16.6 1.5e-06 28.2 6.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AJW71685.1 - 3.1e-07 31.2 6.3 0.0011 19.8 2.6 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AJW71685.1 - 4.2e-07 30.0 7.3 4.9e-06 26.6 7.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AJW71685.1 - 5.9e-07 29.8 0.5 0.016 15.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AJW71685.1 - 6e-07 29.5 5.4 0.00094 19.3 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AJW71685.1 - 5.1e-06 26.3 12.5 0.0094 16.0 3.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AJW71685.1 - 2.6e-05 24.7 5.7 0.027 15.0 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 AJW71685.1 - 0.0003 21.3 4.5 0.0087 16.6 6.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AJW71685.1 - 0.00037 20.6 6.3 0.00049 20.3 4.5 1.9 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AJW71685.1 - 0.00052 20.3 6.4 0.041 14.4 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AJW71685.1 - 0.00067 19.6 11.6 0.051 13.7 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain BCA_ABC_TP_C PF12399.8 AJW71685.1 - 0.00077 19.3 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter Fer4_15 PF13459.6 AJW71685.1 - 0.011 16.5 8.9 0.15 12.8 2.4 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 AJW71685.1 - 0.012 16.4 0.9 5 8.0 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AJW71685.1 - 0.067 14.2 14.9 1.6 9.8 6.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain eIF-6 PF01912.18 AJW71686.1 - 8.5e-65 217.8 0.8 1.1e-64 217.5 0.8 1.1 1 0 0 1 1 1 1 eIF-6 family tRNA-synt_His PF13393.6 AJW71687.1 - 1.2e-45 156.1 0.0 1.7e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AJW71687.1 - 6.9e-13 48.9 0.3 1.3e-12 48.1 0.3 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AJW71687.1 - 1.1e-10 41.5 0.1 6.3e-10 39.1 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.20 AJW71687.1 - 0.0015 18.0 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) RPT PF13446.6 AJW71687.1 - 0.022 14.7 0.3 0.049 13.6 0.3 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Aldo_ket_red PF00248.21 AJW71688.1 - 3.2e-53 180.8 0.0 3.7e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LD_cluster3 PF18180.1 AJW71688.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 SLOG cluster3 family BLACT_WH PF17778.1 AJW71688.1 - 0.37 10.8 1.1 0.71 9.9 0.5 1.7 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Excalibur PF05901.11 AJW71689.1 - 0.0019 18.7 0.6 0.0045 17.6 0.6 1.6 1 0 0 1 1 1 1 Excalibur calcium-binding domain SNase PF00565.17 AJW71689.1 - 0.028 14.9 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal nuclease homologue SKG6 PF08693.10 AJW71689.1 - 0.24 10.8 1.0 0.44 10.0 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3106 PF11304.8 AJW71690.1 - 0.00066 20.1 21.1 2.5 8.6 1.6 7.1 3 2 4 7 7 7 4 Protein of unknown function (DUF3106) YxiJ PF14176.6 AJW71690.1 - 0.015 15.8 3.7 47 4.5 0.0 4.7 4 1 0 4 4 4 0 YxiJ-like protein UDG PF03167.19 AJW71691.1 - 3.6e-29 101.7 0.0 5.1e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GSDH PF07995.11 AJW71694.1 - 2.9e-90 302.9 0.1 4e-90 302.5 0.1 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DUF72 PF01904.18 AJW71695.1 - 5.3e-47 160.7 0.0 6.1e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 SNARE_assoc PF09335.11 AJW71696.1 - 1.9e-19 70.3 6.4 2.3e-19 70.1 5.7 1.5 1 1 0 1 1 1 1 SNARE associated Golgi protein ADH_N PF08240.12 AJW71698.1 - 1.5e-23 82.7 0.3 2.2e-23 82.2 0.3 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 AJW71698.1 - 3.1e-09 36.6 0.0 5.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 AJW71698.1 - 1.9e-06 27.9 0.0 5.3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 AJW71698.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 AJW71698.1 - 0.048 14.7 0.0 0.11 13.6 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Glyoxalase PF00903.25 AJW71699.1 - 0.00066 19.9 0.0 0.00068 19.8 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AJW71699.1 - 0.0037 18.0 0.0 0.0063 17.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain HD_4 PF13328.6 AJW71700.1 - 2.1e-12 47.0 0.0 2.9e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 HD domain Archease PF01951.16 AJW71701.1 - 1.4e-31 109.5 0.3 1.6e-31 109.4 0.3 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) He_PIG PF05345.12 AJW71702.1 - 0.0015 18.7 0.9 0.0037 17.4 0.2 2.1 2 0 0 2 2 2 1 Putative Ig domain fn3 PF00041.21 AJW71703.1 - 2.2e-37 127.2 13.2 5.8e-15 55.4 2.6 4.6 4 1 0 4 4 4 3 Fibronectin type III domain NHL PF01436.21 AJW71703.1 - 1.5e-28 97.3 8.3 4.9e-07 29.5 0.1 6.6 6 0 0 6 6 6 5 NHL repeat DUF5128 PF17170.4 AJW71703.1 - 9.9e-10 38.1 18.9 6.4e-05 22.2 2.2 5.1 3 2 2 5 5 5 2 6-bladed beta-propeller Lactonase PF10282.9 AJW71703.1 - 3.8e-09 36.3 6.1 0.1 11.8 0.1 5.3 3 1 1 5 5 5 4 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 AJW71703.1 - 4.3e-08 33.2 0.0 2.3 8.4 0.0 5.4 5 0 0 5 5 5 1 Arylesterase SGL PF08450.12 AJW71703.1 - 5e-07 29.6 6.6 0.084 12.4 0.0 4.9 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Pur_ac_phosph_N PF16656.5 AJW71703.1 - 2.9e-05 24.6 18.3 0.19 12.3 1.4 5.0 4 2 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain He_PIG PF05345.12 AJW71703.1 - 0.00013 22.0 3.4 0.009 16.2 0.1 3.8 3 0 0 3 3 3 1 Putative Ig domain fn3_4 PF16794.5 AJW71703.1 - 0.052 13.5 0.1 7.6 6.5 0.0 3.7 4 0 0 4 4 4 0 Fibronectin-III type domain MRJP PF03022.16 AJW71703.1 - 0.078 12.3 0.3 4.3 6.6 0.1 3.1 3 1 0 3 3 3 0 Major royal jelly protein Secretin_N PF03958.17 AJW71703.1 - 0.17 12.3 2.1 6.7 7.2 0.0 3.3 3 1 0 3 3 2 0 Bacterial type II/III secretion system short domain DUF2369 PF10179.9 AJW71703.1 - 0.32 11.4 2.5 11 6.4 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) PGM_PMM_II PF02879.16 AJW71703.1 - 0.48 11.1 3.7 15 6.3 0.0 3.3 2 1 2 4 4 4 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Occludin_ELL PF07303.13 AJW71703.1 - 0.78 10.5 6.2 12 6.7 0.5 2.4 2 0 0 2 2 2 0 Occludin homology domain TF_Zn_Ribbon PF08271.12 AJW71704.1 - 0.01 15.3 1.4 0.54 9.8 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DUF1451 PF07295.11 AJW71704.1 - 0.045 13.8 0.3 0.053 13.6 0.3 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain DYW_deaminase PF14432.6 AJW71704.1 - 0.05 13.5 0.2 0.053 13.4 0.2 1.1 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases HypA PF01155.19 AJW71704.1 - 0.074 13.1 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 AJW71704.1 - 0.091 12.8 1.2 2.1 8.4 0.2 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2 PF00096.26 AJW71704.1 - 0.15 12.5 1.6 6.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AJW71704.1 - 0.16 12.9 1.1 8.7 7.5 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RRN7 PF11781.8 AJW71704.1 - 0.45 10.2 3.8 0.94 9.2 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Thioredoxin PF00085.20 AJW71705.1 - 1e-29 102.5 0.0 1.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AJW71705.1 - 9.8e-09 35.6 0.1 3e-08 34.1 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 AJW71705.1 - 9.4e-08 31.7 0.1 1.6e-07 31.0 0.1 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 AJW71705.1 - 9.4e-08 32.3 0.5 2.2e-06 27.9 0.0 2.3 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AJW71705.1 - 6e-07 29.3 0.1 1.1e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 AJW71705.1 - 1e-05 25.3 0.1 2.6e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Redoxin Phosducin PF02114.16 AJW71705.1 - 5.8e-05 22.2 0.0 6.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.6 AJW71705.1 - 0.00053 20.0 0.0 0.00091 19.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 AJW71705.1 - 0.0006 19.7 0.1 0.00093 19.1 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 AJW71705.1 - 0.0015 18.4 0.0 0.0024 17.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 AJW71705.1 - 0.004 17.3 0.6 0.01 16.0 0.1 1.9 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 AJW71705.1 - 0.005 16.8 0.1 0.0063 16.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 AJW71705.1 - 0.0069 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Toxin-deaminase PF14424.6 AJW71705.1 - 0.025 14.7 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Glutaredoxin PF00462.24 AJW71705.1 - 0.026 14.8 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin DUF836 PF05768.14 AJW71705.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GTP_EFTU PF00009.27 AJW71706.1 - 1.9e-33 115.6 0.0 4e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AJW71706.1 - 7.7e-23 80.6 1.1 2.4e-22 79.1 1.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 AJW71706.1 - 1.3e-21 76.2 0.0 4.4e-21 74.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 AJW71706.1 - 1.3e-08 34.9 0.4 1.3e-07 31.7 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AJW71706.1 - 8.6e-06 26.1 0.0 0.00015 22.1 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 AJW71706.1 - 6.6e-05 23.1 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 AJW71706.1 - 7.2e-05 22.7 0.0 0.00031 20.6 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 AJW71706.1 - 0.00055 20.0 0.3 0.06 13.4 0.1 2.7 2 1 0 2 2 2 1 Dynamin family Ras PF00071.22 AJW71706.1 - 0.0036 16.9 0.0 0.018 14.6 0.0 2.1 1 1 0 1 1 1 1 Ras family cobW PF02492.19 AJW71706.1 - 0.028 14.0 0.2 2.3 7.8 0.2 2.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NDK PF00334.19 AJW71707.1 - 1.1e-49 167.8 0.0 1.3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ribosomal_S28e PF01200.18 AJW71708.1 - 5.9e-27 93.4 6.0 6.5e-27 93.3 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L7Ae PF01248.26 AJW71709.1 - 1e-25 89.2 0.1 1.2e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 AJW71709.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain PGM_PMM_I PF02878.16 AJW71710.1 - 2.1e-35 121.4 0.0 4e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AJW71710.1 - 2.5e-25 89.1 0.0 7.5e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AJW71710.1 - 9.3e-20 70.9 0.0 1.5e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AJW71710.1 - 4.7e-11 42.7 0.0 9.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CinA_KH PF18146.1 AJW71710.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain SMC_ScpB PF04079.16 AJW71710.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Formyl_trans_N PF00551.19 AJW71711.1 - 3e-43 147.7 0.0 4.7e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 AJW71711.1 - 1.5e-06 28.0 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AJW71711.1 - 0.019 15.5 0.4 0.067 13.8 0.0 2.1 2 1 0 2 2 2 0 ACT domain PrpR_N PF06506.11 AJW71711.1 - 0.04 13.5 0.1 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 Propionate catabolism activator DUF4411 PF14367.6 AJW71711.1 - 0.062 13.2 0.3 0.13 12.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) Creatininase PF02633.14 AJW71712.1 - 1.1e-50 172.4 0.0 1.3e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Flagellin_C PF00700.21 AJW71713.1 - 0.013 15.8 0.5 0.013 15.8 0.5 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Peptidase_M60_C PF18630.1 AJW71713.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase M60 C-terminal domain Rib_5-P_isom_A PF06026.14 AJW71714.1 - 1e-54 184.7 0.1 1.3e-54 184.4 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AJW71714.1 - 8.1e-05 22.6 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain PCMT PF01135.19 AJW71715.1 - 1.9e-63 214.0 0.0 2.4e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AJW71715.1 - 3.5e-08 33.4 0.0 5.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 AJW71715.1 - 8.2e-07 29.0 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 AJW71715.1 - 2e-06 27.1 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 AJW71715.1 - 4.7e-06 26.4 0.0 8.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 AJW71715.1 - 5.8e-05 22.7 0.0 0.00021 20.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AJW71715.1 - 0.00016 22.3 0.0 0.00039 21.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 AJW71715.1 - 0.00039 19.8 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 AJW71715.1 - 0.00053 19.5 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 AJW71715.1 - 0.0015 18.4 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 AJW71715.1 - 0.0018 17.4 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_4 PF02390.17 AJW71715.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 AJW71715.1 - 0.023 15.3 0.0 0.039 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 AJW71715.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 AJW71715.1 - 0.13 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 AJW71715.1 - 0.23 11.4 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SATase_N PF06426.14 AJW71716.1 - 0.17 12.3 1.2 36 4.8 0.0 3.1 2 1 1 3 3 3 0 Serine acetyltransferase, N-terminal DUF2946 PF11162.8 AJW71716.1 - 0.23 12.1 2.4 0.56 10.9 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TetR_C_28 PF17937.1 AJW71716.1 - 0.25 11.8 1.4 51 4.4 0.1 3.3 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Amidohydro_1 PF01979.20 AJW71717.1 - 2.8e-18 66.4 0.5 3.4e-17 62.8 0.5 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AJW71717.1 - 5.4e-10 39.3 0.1 0.00013 21.6 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family TatD_DNase PF01026.21 AJW71717.1 - 0.0003 20.2 0.1 0.00078 18.9 0.1 1.8 1 1 0 1 1 1 1 TatD related DNase zinc_ribbon_2 PF13240.6 AJW71719.1 - 5.4e-08 32.3 3.1 1e-07 31.5 3.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AJW71719.1 - 5.6e-07 28.7 2.1 9e-07 28.1 2.1 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJW71719.1 - 3e-06 27.2 0.7 5.1e-06 26.4 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 AJW71719.1 - 0.00015 22.4 0.2 0.00019 22.1 0.2 1.2 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 AJW71719.1 - 0.0003 20.8 4.0 0.0007 19.6 4.0 1.6 1 1 1 2 2 2 1 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 AJW71719.1 - 0.00062 19.6 4.7 0.16 11.9 0.2 2.4 2 0 0 2 2 2 2 Nudix N-terminal RNA_POL_M_15KD PF02150.16 AJW71719.1 - 0.008 16.0 2.9 2.3 8.2 0.1 2.3 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 AJW71719.1 - 0.025 14.3 4.1 1 9.1 0.3 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.10 AJW71719.1 - 0.041 13.6 3.5 2.8 7.8 0.2 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain zf_UBZ PF18439.1 AJW71719.1 - 0.082 12.5 3.2 1.1 8.9 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger GFA PF04828.14 AJW71719.1 - 0.11 12.8 3.3 1.8 8.9 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Prok-RING_1 PF14446.6 AJW71719.1 - 0.12 12.3 1.4 0.19 11.7 1.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 YhfH PF14149.6 AJW71719.1 - 0.25 11.3 3.8 7.2 6.7 0.1 2.3 1 1 1 2 2 2 0 YhfH-like protein RecR PF02132.15 AJW71719.1 - 0.26 10.9 1.3 5.4 6.7 1.3 2.2 1 1 0 1 1 1 0 RecR protein HscB_4_cys PF18256.1 AJW71719.1 - 0.37 10.7 4.2 3.4 7.6 0.1 2.3 1 1 1 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif NOB1_Zn_bind PF08772.11 AJW71719.1 - 0.74 10.0 6.8 18 5.6 0.6 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like LisH_2 PF16045.5 AJW71719.1 - 4.5 6.4 8.9 5.3 6.2 0.7 3.0 3 0 0 3 3 3 0 LisH zinc_ribbon_2 PF13240.6 AJW71720.1 - 3.5e-07 29.7 3.4 5.7e-07 29.1 3.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AJW71720.1 - 0.0002 21.3 1.4 0.00029 20.8 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AJW71720.1 - 0.00029 20.1 3.2 0.00051 19.4 3.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AJW71720.1 - 0.0025 18.5 0.4 0.0065 17.2 0.2 1.7 2 0 0 2 2 2 1 zinc-ribbon family PAH PF02671.21 AJW71720.1 - 0.32 11.2 3.0 0.15 12.2 0.7 1.6 2 0 0 2 2 2 0 Paired amphipathic helix repeat zf-NADH-PPase PF09297.11 AJW71720.1 - 1 9.0 4.6 7.7 6.3 0.8 2.3 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 AJW71720.1 - 2.2 8.2 6.5 4.9 7.2 1.4 2.2 2 0 0 2 2 2 0 Nudix N-terminal Thioredoxin PF00085.20 AJW71721.1 - 9.4e-31 105.9 0.1 1e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AJW71721.1 - 1.1e-10 41.7 0.1 1.9e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 AJW71721.1 - 7.2e-09 36.1 0.0 2.5e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AJW71721.1 - 2.1e-05 24.6 0.1 3.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 AJW71721.1 - 2.6e-05 24.2 0.1 3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 AJW71721.1 - 2.7e-05 23.9 0.0 3.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 AJW71721.1 - 0.00022 21.1 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 AJW71721.1 - 0.00063 19.5 0.1 0.00091 19.0 0.1 1.3 1 1 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 AJW71721.1 - 0.0024 17.3 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 AJW71721.1 - 0.0028 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 AJW71721.1 - 0.0059 16.2 0.3 0.019 14.6 0.3 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 AJW71721.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF836 PF05768.14 AJW71721.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DZR PF12773.7 AJW71722.1 - 1.4e-06 28.2 9.1 0.00056 19.9 3.0 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 AJW71722.1 - 9.9e-06 25.1 8.5 9.9e-06 25.1 8.5 2.9 3 0 0 3 3 3 1 zinc-ribbon domain PRC PF05239.16 AJW71722.1 - 2.5e-05 24.3 0.4 4.7e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 PRC-barrel domain zinc_ribbon_15 PF17032.5 AJW71722.1 - 2.7e-05 24.8 2.4 0.087 13.6 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon family zf-ribbon_3 PF13248.6 AJW71722.1 - 0.0043 16.4 4.4 0.0043 16.4 4.4 2.8 3 0 0 3 3 3 1 zinc-ribbon domain zf-B_box PF00643.24 AJW71722.1 - 0.13 12.5 8.7 1.1 9.5 0.5 3.1 3 0 0 3 3 3 0 B-box zinc finger GFA PF04828.14 AJW71722.1 - 0.17 12.2 4.4 27 5.2 0.0 3.5 3 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-RRN7 PF11781.8 AJW71722.1 - 0.65 9.7 12.1 0.77 9.5 3.1 2.7 3 0 0 3 3 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc-ribbons_6 PF07191.12 AJW71722.1 - 0.74 9.8 8.1 12 5.9 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbons zf-AD PF07776.15 AJW71722.1 - 0.77 10.0 0.1 0.77 10.0 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Tnp_zf-ribbon_2 PF13842.6 AJW71722.1 - 2.8 8.8 11.2 8.7 7.2 0.3 3.3 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Gin PF10764.9 AJW71722.1 - 4.9 7.2 10.9 1.1 9.2 0.2 3.2 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin zf-CHY PF05495.12 AJW71722.1 - 5.3 7.6 7.9 22 5.6 2.2 2.6 2 1 0 2 2 2 0 CHY zinc finger Peptidase_S24 PF00717.23 AJW71723.1 - 6.4e-08 32.4 0.5 1.5e-07 31.2 0.5 1.7 1 0 0 1 1 1 1 Peptidase S24-like MscL PF01741.18 AJW71723.1 - 0.0015 18.8 0.3 0.0015 18.8 0.3 1.8 2 1 0 2 2 2 1 Large-conductance mechanosensitive channel, MscL Ureide_permease PF07168.11 AJW71723.1 - 0.16 10.7 0.1 0.23 10.1 0.1 1.2 1 0 0 1 1 1 0 Ureide permease HpaB_N PF11794.8 AJW71724.1 - 1.6e-95 319.9 0.0 2.8e-95 319.1 0.0 1.4 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 AJW71724.1 - 9.8e-73 243.5 0.1 1.3e-72 243.1 0.1 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Bt_P21 PF05560.11 AJW71724.1 - 0.066 12.8 0.2 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein Acyl-CoA_dh_M PF02770.19 AJW71724.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Herpes_LP PF03363.13 AJW71724.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus leader protein ATP-grasp_5 PF13549.6 AJW71725.1 - 1.5e-78 263.3 2.0 1.9e-78 263.0 0.9 1.8 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AJW71725.1 - 3.8e-53 179.0 0.8 1.1e-52 177.5 0.8 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AJW71725.1 - 3.2e-23 82.4 1.8 9.6e-23 80.9 0.1 2.6 3 1 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 AJW71725.1 - 3.4e-07 30.8 3.7 4.6e-07 30.4 0.7 2.6 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 AJW71725.1 - 7.5e-06 25.6 2.9 1.8e-05 24.4 2.9 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AJW71725.1 - 0.001 18.6 0.2 0.0022 17.5 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AJW71725.1 - 0.045 13.3 0.3 0.19 11.3 0.3 2.1 1 1 0 1 1 1 0 ATP-grasp domain 5_3_exonuc_N PF02739.16 AJW71725.1 - 0.079 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain RVT_3 PF13456.6 AJW71726.1 - 5.7e-13 48.8 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 AJW71726.1 - 6e-12 46.0 0.0 7.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 RNase H HAD_SAK_1 PF10307.9 AJW71726.1 - 0.0098 15.7 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DUF3270 PF11674.8 AJW71727.1 - 0.00048 20.3 2.0 0.053 13.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3270) DUF3792 PF12670.7 AJW71727.1 - 0.015 15.5 0.6 0.015 15.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF3784 PF12650.7 AJW71727.1 - 0.019 15.1 1.8 0.019 15.1 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) MARVEL PF01284.23 AJW71727.1 - 0.11 12.5 5.1 8.4 6.4 3.4 2.1 2 0 0 2 2 2 0 Membrane-associating domain HTH_5 PF01022.20 AJW71729.1 - 3.3e-09 36.5 0.1 2.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AJW71729.1 - 1.3e-05 25.2 0.0 2.7e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_45 PF14947.6 AJW71729.1 - 0.00032 20.6 0.6 0.0004 20.3 0.6 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.19 AJW71729.1 - 0.00072 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Phage_rep_O PF04492.13 AJW71729.1 - 0.0029 18.1 0.1 0.0037 17.8 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage replication protein O B-block_TFIIIC PF04182.12 AJW71729.1 - 0.0032 17.6 0.1 0.0046 17.1 0.1 1.2 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_12 PF08461.10 AJW71729.1 - 0.0044 16.9 0.1 0.007 16.3 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain DUF4423 PF14394.6 AJW71729.1 - 0.0048 16.6 0.7 0.026 14.2 0.3 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4423) HTH_11 PF08279.12 AJW71729.1 - 0.0058 16.5 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AJW71729.1 - 0.031 13.8 0.1 0.053 13.1 0.1 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 AJW71729.1 - 0.043 14.2 0.1 0.081 13.3 0.1 1.5 1 1 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 AJW71729.1 - 0.044 13.7 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 AJW71729.1 - 0.046 13.8 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix MarR_2 PF12802.7 AJW71729.1 - 0.054 13.4 0.0 0.087 12.7 0.0 1.5 2 0 0 2 2 2 0 MarR family Radical_SAM PF04055.21 AJW71730.1 - 2.6e-14 54.0 0.0 4.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily IMPDH PF00478.25 AJW71730.1 - 0.0019 17.3 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Gaa1 PF04114.14 AJW71733.1 - 0.089 11.8 4.7 0.1 11.6 4.7 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Acetyltransf_1 PF00583.25 AJW71734.1 - 4.7e-14 52.6 0.0 5.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AJW71734.1 - 6.3e-11 42.3 0.0 7.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJW71734.1 - 2.3e-10 40.7 0.1 3.3e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AJW71734.1 - 2.7e-06 27.6 0.0 3.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJW71734.1 - 0.0026 17.7 0.0 0.0058 16.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein PanZ PF12568.8 AJW71734.1 - 0.0049 16.6 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 AJW71734.1 - 0.01 15.3 3.5 0.04 13.4 1.7 2.2 2 1 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 AJW71734.1 - 0.058 13.5 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Response_reg PF00072.24 AJW71735.1 - 2.1e-25 89.1 0.6 2.3e-25 88.9 0.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AJW71735.1 - 0.0044 17.4 0.1 0.0051 17.2 0.1 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ DUF373 PF04123.13 AJW71735.1 - 0.057 12.9 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Cnd1_N PF12922.7 AJW71735.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term HATPase_c PF02518.26 AJW71736.1 - 1e-18 67.9 0.2 2e-18 66.9 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AJW71736.1 - 2.3e-09 37.1 0.0 5.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AJW71736.1 - 4.7e-06 26.4 0.2 4.7e-06 26.4 0.2 1.8 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 AJW71736.1 - 0.0061 16.4 0.9 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4293 PF14126.6 AJW71736.1 - 0.015 15.5 9.5 0.13 12.5 2.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) CobD_Cbib PF03186.13 AJW71736.1 - 0.044 13.0 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 CobD/Cbib protein HATPase_c_2 PF13581.6 AJW71736.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain SPC25 PF06703.11 AJW71736.1 - 1.8 8.3 5.0 0.27 11.0 0.1 2.1 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Phage_holin_5_2 PF16079.5 AJW71736.1 - 7.9 6.9 13.1 4.8 7.6 2.0 3.2 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V VirB3 PF05101.13 AJW71736.1 - 8 6.8 12.7 1.4 9.2 0.6 3.3 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Methyltransf_25 PF13649.6 AJW71737.1 - 1e-16 61.4 0.0 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJW71737.1 - 8.3e-16 58.4 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AJW71737.1 - 9.8e-12 44.9 0.2 1.3e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW71737.1 - 5.7e-09 36.0 0.0 6.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW71737.1 - 7.9e-09 36.2 0.0 1.6e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AJW71737.1 - 1.1e-05 24.9 0.1 1.4e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AJW71737.1 - 0.0034 17.0 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AJW71737.1 - 0.029 13.9 0.0 0.08 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain CheR PF01739.18 AJW71737.1 - 0.034 13.6 0.5 8.1 5.9 0.1 3.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PSI_PsaH PF03244.14 AJW71737.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Aminotran_4 PF01063.19 AJW71738.1 - 2.6e-49 168.1 0.0 3.2e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV AA_kinase PF00696.28 AJW71740.1 - 9.4e-29 100.7 0.5 2.1e-28 99.6 0.5 1.6 1 0 0 1 1 1 1 Amino acid kinase family YajC PF02699.15 AJW71740.1 - 0.011 15.5 0.1 0.065 13.1 0.0 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit ACT PF01842.25 AJW71740.1 - 0.12 12.2 2.4 0.18 11.6 0.7 2.2 2 0 0 2 2 2 0 ACT domain Glyco_tran_28_C PF04101.16 AJW71741.1 - 1.8e-12 47.5 0.0 3.8e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 AJW71741.1 - 6.6e-05 22.3 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.6 AJW71741.1 - 0.0013 19.2 0.0 0.0034 17.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 CCDC117 PF15810.5 AJW71741.1 - 0.072 13.4 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 Glycos_transf_1 PF00534.20 AJW71741.1 - 0.1 12.1 0.2 0.78 9.3 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 TEBP_beta PF07404.11 AJW71741.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Phage_integrase PF00589.22 AJW71742.1 - 0.0065 16.3 0.0 0.076 12.8 0.0 2.2 1 1 0 1 1 1 1 Phage integrase family VAPB_antitox PF02697.14 AJW71743.1 - 0.0049 17.6 0.1 0.0052 17.5 0.1 1.0 1 0 0 1 1 1 1 Putative antitoxin HNH_5 PF14279.6 AJW71745.1 - 0.0031 17.3 2.1 0.0076 16.1 2.1 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 AJW71745.1 - 0.0053 16.9 5.1 0.01 16.0 5.1 1.6 1 0 0 1 1 1 1 HNH endonuclease CENP-H PF05837.12 AJW71745.1 - 0.016 15.6 0.3 0.028 14.8 0.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Integrase_Zn PF02022.19 AJW71745.1 - 0.69 9.9 4.2 2 8.5 1.0 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain DUF5336 PF17270.2 AJW71746.1 - 0.87 9.2 5.1 0.69 9.5 1.0 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5336) PHD PF00628.29 AJW71747.1 - 0.041 13.8 0.8 0.072 13.0 0.8 1.4 1 0 0 1 1 1 0 PHD-finger FBD PF08387.10 AJW71749.1 - 0.04 13.8 0.2 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 FBD Ribosomal_S19e PF01090.19 AJW71749.1 - 0.06 13.1 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e PadR PF03551.14 AJW71749.1 - 0.091 12.7 0.1 0.2 11.6 0.1 1.6 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family TrmB PF01978.19 AJW71749.1 - 0.11 12.4 0.3 2.3 8.1 0.3 2.2 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Type2_restr_D3 PF16902.5 AJW71750.1 - 0.11 12.4 0.5 0.67 9.9 0.1 2.1 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Multi_ubiq PF14452.6 AJW71751.1 - 2.4e-18 66.1 0.1 2.7e-18 66.0 0.1 1.0 1 0 0 1 1 1 1 Multiubiquitin DUF2207 PF09972.9 AJW71754.1 - 0.36 9.5 1.7 0.42 9.3 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CAP PF00188.26 AJW71755.1 - 2.4e-19 70.4 0.5 2.4e-19 70.4 0.5 2.0 2 1 0 2 2 2 1 Cysteine-rich secretory protein family THP2 PF09432.10 AJW71755.1 - 0.0017 18.4 2.2 1.5 8.9 0.1 2.3 1 1 0 2 2 2 2 Tho complex subunit THP2 CBM_5_12_2 PF14600.6 AJW71755.1 - 0.0035 17.2 0.3 0.0078 16.1 0.3 1.5 1 0 0 1 1 1 1 Cellulose-binding domain A2L_zn_ribbon PF08792.10 AJW71755.1 - 0.018 14.7 1.7 0.043 13.5 1.7 1.7 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF2232 PF09991.9 AJW71755.1 - 0.04 13.1 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Prominin PF05478.11 AJW71755.1 - 0.97 7.3 8.2 1.5 6.7 3.2 2.0 1 1 1 2 2 2 0 Prominin 2_5_RNA_ligase2 PF13563.6 AJW71756.1 - 2.4e-17 63.2 0.0 3.7e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 AJW71756.1 - 0.013 15.7 0.1 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase Cupredoxin_1 PF13473.6 AJW71758.1 - 5.5e-05 23.2 0.0 0.08 13.1 0.0 3.6 3 0 0 3 3 3 1 Cupredoxin-like domain Copper-bind PF00127.20 AJW71758.1 - 6.4e-05 23.3 0.2 0.22 12.0 0.0 2.9 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family MG2 PF01835.19 AJW71758.1 - 0.00014 22.3 0.1 0.0014 19.1 0.1 2.5 2 0 0 2 2 2 1 MG2 domain A2M_BRD PF07703.14 AJW71758.1 - 0.0091 16.3 0.8 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 AJW71759.1 - 2.7e-07 30.9 0.0 4.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 MG2 domain PAS_7 PF12860.7 AJW71759.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold Response_reg PF00072.24 AJW71760.1 - 4.2e-29 101.0 0.4 4.8e-29 100.8 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF1307 PF06998.11 AJW71760.1 - 0.042 13.9 0.7 0.059 13.4 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1307) Response_reg PF00072.24 AJW71761.1 - 9.6e-19 67.6 0.1 1.2e-18 67.3 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 AJW71762.1 - 1.2e-22 80.2 0.0 1.3e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AJW71762.1 - 0.048 13.7 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain 2-Hacid_dh_C PF02826.19 AJW71762.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_RFF PF18321.1 AJW71762.1 - 0.12 12.8 0.0 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HisKA PF00512.25 AJW71763.1 - 0.0037 17.3 0.1 0.0047 16.9 0.1 1.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SesA PF17107.5 AJW71763.1 - 0.0075 16.5 0.1 0.0096 16.1 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3848 PF12959.7 AJW71763.1 - 0.028 14.5 0.5 0.03 14.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) DUF244 PF03112.14 AJW71763.1 - 0.21 11.5 2.5 0.21 11.4 2.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Polyketide_cyc2 PF10604.9 AJW71765.1 - 1.5e-07 31.8 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AJW71765.1 - 2.3e-06 27.8 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 AJW71765.1 - 2.6e-06 27.7 0.0 4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FeoB_associated PF12669.7 AJW71766.1 - 0.074 13.5 0.4 0.074 13.5 0.4 1.9 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Col_cuticle_N PF01484.17 AJW71766.1 - 5.5 7.1 9.6 2.6 8.2 1.7 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain COX15-CtaA PF02628.15 AJW71767.1 - 2.4e-16 59.7 15.3 3.2e-12 46.2 7.7 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein Copper-bind PF00127.20 AJW71768.1 - 1.6e-14 54.2 0.2 1.2e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.15 AJW71768.1 - 1.4e-13 50.9 0.7 1.2e-05 25.3 0.2 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 AJW71768.1 - 2.1e-07 31.0 0.0 0.0079 16.3 0.0 2.6 2 0 0 2 2 2 2 Cupredoxin-like domain Cu-oxidase_2 PF07731.14 AJW71768.1 - 3.9e-07 29.9 0.0 0.027 14.2 0.0 3.1 3 1 0 3 3 3 2 Multicopper oxidase SoxE PF06525.11 AJW71768.1 - 1.6e-06 27.6 3.9 0.025 14.0 0.2 3.2 2 2 0 2 2 2 2 Sulfocyanin (SoxE) domain Cu_bind_like PF02298.17 AJW71768.1 - 7.3e-06 25.9 0.1 0.15 12.1 0.1 3.0 2 1 0 2 2 2 2 Plastocyanin-like domain OST_P2 PF18235.1 AJW71768.1 - 0.013 15.4 0.0 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain CHU_C PF13585.6 AJW71768.1 - 0.022 14.8 0.2 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of CHU protein family DUF5599 PF18141.1 AJW71768.1 - 0.085 13.1 0.0 14 6.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5599) TolB_N PF04052.13 AJW71768.1 - 0.15 12.3 0.1 7.5 6.8 0.0 2.2 2 0 0 2 2 2 0 TolB amino-terminal domain PPC PF04151.15 AJW71768.1 - 0.3 12.2 0.3 0.3 12.2 0.3 3.0 2 1 1 3 3 3 0 Bacterial pre-peptidase C-terminal domain COX1 PF00115.20 AJW71769.1 - 3.9e-131 437.9 60.2 4.7e-131 437.6 60.2 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 AJW71770.1 - 1.7e-15 56.9 1.3 5.5e-12 45.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AJW71770.1 - 6.1e-05 23.1 0.0 7e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Cupredoxin-like domain FeoB_associated PF12669.7 AJW71771.1 - 0.64 10.5 2.3 6.8 7.2 0.0 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein His_Phos_1 PF00300.22 AJW71772.1 - 3.1e-49 167.3 0.0 3.4e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lipase_GDSL_3 PF14606.6 AJW71772.1 - 0.039 14.1 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CRM1_C PF08767.11 AJW71772.1 - 0.051 12.7 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal F420_oxidored PF03807.17 AJW71773.1 - 1.4e-14 54.5 0.0 2.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AJW71773.1 - 0.018 15.3 0.1 0.042 14.1 0.1 1.7 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 AJW71773.1 - 0.029 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 AJW71773.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Semialdhyde_dh PF01118.24 AJW71773.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 AJW71773.1 - 0.085 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_Gly3P_dh_N PF01210.23 AJW71773.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Gram_pos_anchor PF00746.21 AJW71774.1 - 0.19 11.7 0.0 21 5.2 0.0 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF202 PF02656.15 AJW71774.1 - 0.21 12.0 1.5 0.91 10.0 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 AJW71774.1 - 1.3 8.6 4.2 1.6 8.4 4.2 1.0 1 0 0 1 1 1 0 Tetraspanin family Saf_2TM PF18303.1 AJW71774.1 - 6.2 6.4 6.6 32 4.1 6.3 1.8 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain Putative_PNPOx PF01243.20 AJW71775.1 - 8.3e-15 54.8 0.0 1.8e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AJW71775.1 - 3.6e-10 40.0 0.0 4.6e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_1_2 PF00155.21 AJW71776.1 - 1.1e-59 202.4 0.0 1.3e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AJW71776.1 - 6e-07 28.7 0.0 1.6e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AJW71776.1 - 5.6e-06 25.9 0.0 9.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AJW71776.1 - 0.0074 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 AJW71776.1 - 0.016 14.0 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 AJW71776.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase HRDC PF00570.23 AJW71776.1 - 0.17 11.9 0.1 28 4.8 0.0 3.1 3 1 1 4 4 4 0 HRDC domain Saf_2TM PF18303.1 AJW71777.1 - 0.02 14.5 0.2 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PIRT PF15099.6 AJW71777.1 - 0.052 13.1 0.5 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family adh_short_C2 PF13561.6 AJW71779.1 - 2e-19 70.1 0.0 1.2e-16 61.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AJW71779.1 - 9.2e-19 67.7 0.1 9.5e-13 48.0 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.17 AJW71779.1 - 0.0015 17.6 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AJW71779.1 - 0.002 17.6 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 AJW71779.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 AJW71780.1 - 2e-07 31.6 0.0 8.7e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW71780.1 - 1.3e-06 28.4 0.0 2.4e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW71780.1 - 1.7e-05 25.4 0.0 0.00017 22.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW71780.1 - 0.051 14.3 0.1 0.2 12.4 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF243 PF03103.17 AJW71780.1 - 0.052 13.9 0.1 0.086 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF243) GRAS PF03514.14 AJW71780.1 - 0.16 10.9 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 GRAS domain family Polysacc_deac_1 PF01522.21 AJW71781.1 - 5.9e-16 58.5 0.0 1.1e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide deacetylase Hexokinase_1 PF00349.21 AJW71781.1 - 0.067 13.1 0.0 0.5 10.2 0.0 2.4 1 1 0 1 1 1 0 Hexokinase Sulfotransfer_1 PF00685.27 AJW71782.1 - 5.2e-16 58.9 0.3 6.5e-16 58.6 0.3 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 AJW71782.1 - 2.9e-13 50.7 0.0 1.2e-08 35.6 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 AJW71782.1 - 0.00062 19.7 1.6 0.0018 18.2 1.6 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 AJW71782.1 - 0.1 12.4 0.1 0.95 9.2 0.1 2.3 1 1 0 1 1 1 0 Sulfotransferase domain FeS_assembly_P PF01883.19 AJW71783.1 - 1.6e-17 63.5 0.1 2.7e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein PqqD PF05402.12 AJW71783.1 - 1.4e-10 41.3 0.1 2.4e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) HemN_C PF06969.16 AJW71783.1 - 0.049 13.7 0.3 0.095 12.8 0.3 1.5 1 0 0 1 1 1 0 HemN C-terminal domain DUF4777 PF16007.5 AJW71783.1 - 0.14 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) IF-2B PF01008.17 AJW71785.1 - 1.2e-86 290.4 2.0 1.5e-86 290.1 2.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RRM_1 PF00076.22 AJW71785.1 - 0.004 17.0 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serine_rich PF08824.10 AJW71785.1 - 0.021 14.8 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain YokU PF14122.6 AJW71785.1 - 0.16 12.0 0.4 7.7 6.6 0.1 2.5 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin bact-PGI_C PF10432.9 AJW71786.1 - 3.2e-34 118.2 0.0 5.6e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 AJW71786.1 - 4.4e-08 33.0 0.1 1.4e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 SIS domain Tn7_Tnp_TnsA_N PF08722.11 AJW71786.1 - 0.015 15.5 0.3 0.032 14.4 0.3 1.6 1 0 0 1 1 1 0 TnsA endonuclease N terminal Methyltransf_18 PF12847.7 AJW71786.1 - 0.049 13.6 0.3 0.26 11.2 0.1 2.2 1 1 1 2 2 2 0 Methyltransferase domain Epimerase PF01370.21 AJW71787.1 - 2.7e-58 197.3 0.1 3.2e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJW71787.1 - 1.2e-53 182.6 0.3 9.1e-53 179.8 0.3 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJW71787.1 - 2.1e-31 109.0 4.0 2.7e-31 108.6 4.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJW71787.1 - 1.3e-24 86.8 0.0 1.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AJW71787.1 - 2.1e-22 79.6 8.4 1.9e-21 76.5 8.4 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJW71787.1 - 1.3e-18 67.1 1.0 7.5e-13 48.2 0.2 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AJW71787.1 - 2.9e-17 63.2 0.0 4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AJW71787.1 - 6.2e-10 39.0 1.2 1.4e-09 37.9 1.2 1.7 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 AJW71787.1 - 4.4e-06 26.7 0.0 8.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 AJW71787.1 - 9.8e-05 21.9 0.2 0.00029 20.3 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase SpoU_sub_bind PF08032.12 AJW71787.1 - 0.017 15.4 1.3 4.9 7.5 0.0 2.8 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Sacchrp_dh_NADP PF03435.18 AJW71787.1 - 0.026 14.8 0.5 0.062 13.6 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 AJW71787.1 - 0.041 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1506 PF07405.11 AJW71787.1 - 0.087 13.0 1.4 0.17 12.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1506) CTP_transf_3 PF02348.19 AJW71788.1 - 5e-30 105.1 1.5 6.6e-30 104.7 1.5 1.2 1 0 0 1 1 1 1 Cytidylyltransferase DUF2023 PF09633.10 AJW71788.1 - 0.093 12.9 0.3 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2023) NTP_transf_3 PF12804.7 AJW71788.1 - 0.2 12.0 0.0 0.62 10.4 0.0 1.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain Imm68 PF15583.6 AJW71788.1 - 0.26 11.5 3.2 0.28 11.3 0.4 2.2 2 1 0 2 2 2 0 Immunity protein 68 DegT_DnrJ_EryC1 PF01041.17 AJW71789.1 - 8.1e-97 324.7 0.0 9.9e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 AJW71789.1 - 2.1e-08 33.3 0.1 2.6e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 AJW71789.1 - 2.2e-08 33.7 0.0 5.4e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AJW71789.1 - 2.4e-08 33.6 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AJW71789.1 - 4.9e-06 25.3 0.1 9.2e-06 24.4 0.1 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AJW71789.1 - 0.09 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V NeuB PF03102.14 AJW71790.1 - 1.7e-34 119.3 0.3 4.5e-34 118.0 0.3 1.7 1 1 0 1 1 1 1 NeuB family DUF5625 PF18539.1 AJW71790.1 - 0.024 14.9 0.1 0.049 13.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5625) AP_endonuc_2 PF01261.24 AJW71790.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acetyltransf_3 PF13302.7 AJW71791.1 - 5.9e-08 33.5 0.0 6.7e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AJW71791.1 - 6.6e-08 32.9 0.0 9.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AJW71791.1 - 8.8e-08 32.4 0.0 1.1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AJW71791.1 - 3.1e-07 30.6 0.2 4.4e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJW71791.1 - 7e-05 22.8 0.0 9.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJW71791.1 - 0.00044 20.2 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Polysacc_synt_2 PF02719.15 AJW71792.1 - 8.9e-96 320.5 0.1 1.1e-95 320.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AJW71792.1 - 4.6e-29 101.6 0.1 2.8e-28 99.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJW71792.1 - 2.4e-23 82.6 0.1 6.4e-21 74.6 0.1 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AJW71792.1 - 1.3e-18 67.5 0.3 5.4e-17 62.2 0.3 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AJW71792.1 - 8.5e-14 51.3 0.0 4.6e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AJW71792.1 - 3.1e-11 43.5 0.0 4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AJW71792.1 - 5.8e-10 38.8 2.0 4e-07 29.5 0.6 3.0 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 AJW71792.1 - 4.4e-06 26.3 0.0 8.6e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AJW71792.1 - 5.5e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 AJW71792.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 AJW71792.1 - 0.0012 19.3 0.0 0.058 13.8 0.0 2.7 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AJW71792.1 - 0.0086 16.1 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AJW71792.1 - 0.03 14.9 0.0 0.095 13.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyphos_transf PF04464.14 AJW71794.1 - 4.5e-09 35.7 3.0 9.7e-09 34.7 3.0 1.6 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Glyco_transf_9 PF01075.17 AJW71794.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Methyltransf_31 PF13847.6 AJW71795.1 - 2.9e-20 72.6 0.4 5.2e-20 71.8 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AJW71795.1 - 1.3e-15 57.9 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AJW71795.1 - 9.4e-15 55.2 0.1 2e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AJW71795.1 - 7.5e-14 51.9 0.0 1.6e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AJW71795.1 - 7.2e-13 49.0 0.0 1.3e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AJW71795.1 - 6.8e-10 38.4 0.1 1.1e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 AJW71795.1 - 2.8e-07 30.2 0.1 5.6e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.12 AJW71795.1 - 1.8e-05 24.0 0.1 4e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 DREV methyltransferase CheR PF01739.18 AJW71795.1 - 1.8e-05 24.3 0.2 0.00011 21.7 0.1 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 AJW71795.1 - 0.00035 20.2 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 AJW71795.1 - 0.00094 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 AJW71795.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 AJW71795.1 - 0.0029 17.1 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 AJW71795.1 - 0.003 16.9 0.2 0.0049 16.2 0.2 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G DOT1 PF08123.13 AJW71795.1 - 0.006 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Rsm22 PF09243.10 AJW71795.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 NodS PF05401.11 AJW71795.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 AJW71795.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 AJW71795.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) NAD_synthase PF02540.17 AJW71796.1 - 2e-57 194.1 1.4 3.8e-32 111.3 0.3 2.0 1 1 1 2 2 2 2 NAD synthase QueC PF06508.13 AJW71796.1 - 8.7e-06 25.4 0.1 0.0002 21.0 0.0 2.7 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AJW71796.1 - 2.4e-05 23.3 0.1 6.1e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase DUF416 PF04222.12 AJW71796.1 - 0.024 14.1 0.1 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF416) DEAD PF00270.29 AJW71796.1 - 0.036 13.8 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Transposase_22 PF02994.14 AJW71796.1 - 0.3 11.3 2.4 4.3 7.6 0.2 3.0 2 1 0 2 2 2 0 L1 transposable element RBD-like domain Glycos_transf_2 PF00535.26 AJW71797.1 - 1.8e-27 96.2 0.0 2.9e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJW71797.1 - 1.5e-15 57.7 0.0 2.6e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AJW71797.1 - 0.0042 16.6 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AJW71797.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family group 2 ACPS PF01648.20 AJW71798.1 - 3.5e-16 59.3 0.0 4.3e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF5414 PF17435.2 AJW71798.1 - 0.02 14.5 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5414) 3-dmu-9_3-mt PF06983.13 AJW71798.1 - 0.15 12.6 1.3 0.19 12.3 1.3 1.3 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase AMP-binding PF00501.28 AJW71800.1 - 4.7e-72 242.9 0.0 5.5e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AJW71800.1 - 6.3e-11 43.1 0.0 1.5e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5532 PF17673.1 AJW71800.1 - 0.023 14.8 0.3 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5532) HU-HIG PF18291.1 AJW71800.1 - 0.024 14.7 0.1 0.64 10.1 0.0 2.5 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Hexapep_2 PF14602.6 AJW71801.1 - 4e-11 42.5 8.9 5.9e-05 22.7 6.4 3.4 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AJW71801.1 - 2.9e-09 36.3 17.4 0.00012 21.7 7.2 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF2613 PF11021.8 AJW71801.1 - 0.16 12.1 2.5 0.27 11.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) LON_substr_bdg PF02190.16 AJW71802.1 - 0.12 12.2 1.2 0.21 11.4 1.2 1.3 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain MBOAT PF03062.19 AJW71803.1 - 5.2e-32 111.6 4.3 5.2e-32 111.6 4.3 3.0 3 1 1 4 4 4 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AJW71803.1 - 9.1e-05 22.7 1.0 9.1e-05 22.7 1.0 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2198 PF09964.9 AJW71803.1 - 1.5 8.9 11.7 2.4 8.3 5.0 3.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) dTDP_sugar_isom PF00908.17 AJW71804.1 - 8.1e-70 233.9 0.0 9.2e-70 233.7 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase GDP_Man_Dehyd PF16363.5 AJW71805.1 - 2.9e-78 263.6 0.0 3.3e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJW71805.1 - 8.6e-57 192.4 0.0 1.1e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AJW71805.1 - 1.8e-20 73.1 0.0 2.2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AJW71805.1 - 1.1e-15 57.5 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AJW71805.1 - 4.3e-15 55.6 0.1 2.3e-14 53.2 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJW71805.1 - 2e-14 53.4 0.0 2.6e-12 46.5 0.2 2.2 1 1 1 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 AJW71805.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 AJW71805.1 - 0.04 13.4 0.0 0.1 12.0 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 AJW71805.1 - 0.054 13.4 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 AJW71806.1 - 1.1e-65 221.6 0.0 1.2e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AJW71806.1 - 2.4e-23 82.9 0.0 4.5e-23 82.0 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJW71806.1 - 7.6e-15 55.1 0.4 6.7e-14 52.0 0.4 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AJW71806.1 - 1.4e-08 34.2 3.1 6.3e-07 28.8 3.1 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AJW71806.1 - 6.6e-08 32.0 0.1 1.9e-05 23.9 0.1 2.6 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 AJW71806.1 - 1.2e-06 27.8 0.1 1.8e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF5099 PF17025.5 AJW71806.1 - 0.075 13.4 0.8 0.19 12.2 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Myosin-VI_CBD PF16521.5 AJW71806.1 - 0.09 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Myosin VI cargo binding domain Glycos_transf_2 PF00535.26 AJW71807.1 - 2.1e-22 79.7 0.0 2.8e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AJW71807.1 - 1.6e-06 28.2 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AJW71807.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Polbeta PF18765.1 AJW71807.1 - 0.094 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AJW71807.1 - 0.15 12.4 0.1 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 Nucleotidyltransferase domain Capsule_synth PF05159.14 AJW71808.1 - 8.7e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AJW71809.1 - 7.4e-07 29.3 4.5 7.4e-07 29.3 4.5 4.7 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 AJW71809.1 - 0.014 14.6 34.4 0.61 9.3 8.2 3.4 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_24 PF13578.6 AJW71810.1 - 2.1e-18 67.3 0.0 2.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 AJW71810.1 - 5.8e-08 32.2 0.1 9.2e-08 31.5 0.1 1.3 1 1 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 AJW71810.1 - 2.4e-06 27.4 0.0 1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_25 PF13649.6 AJW71810.1 - 0.0011 19.6 0.0 0.0017 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain STATa_Ig PF18214.1 AJW71810.1 - 0.03 14.3 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain PCMT PF01135.19 AJW71810.1 - 0.056 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 AJW71810.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain YfhO PF09586.10 AJW71811.1 - 0.0016 16.8 2.7 0.0019 16.5 2.7 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Glyco_transf_22 PF03901.17 AJW71811.1 - 0.0031 16.8 2.9 0.004 16.4 2.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family APG17 PF04108.12 AJW71811.1 - 0.013 14.7 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Vpu PF00558.19 AJW71811.1 - 0.024 14.4 0.3 0.08 12.7 0.1 1.9 2 0 0 2 2 2 0 Vpu protein MFS_1 PF07690.16 AJW71811.1 - 0.044 12.7 2.4 0.062 12.2 2.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3953 PF13129.6 AJW71811.1 - 0.3 10.9 5.8 0.64 9.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) DUF2207 PF09972.9 AJW71812.1 - 0.034 12.9 0.5 0.039 12.7 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3937 PF13073.6 AJW71812.1 - 0.13 12.4 3.4 0.26 11.4 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) WBP-1 PF11669.8 AJW71812.1 - 0.17 12.6 0.1 0.17 12.6 0.1 1.5 2 0 0 2 2 2 0 WW domain-binding protein 1 NTP_transferase PF00483.23 AJW71814.1 - 1.1e-54 185.6 0.0 1.5e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AJW71814.1 - 1.2e-09 38.8 0.0 1.7e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 AJW71814.1 - 3e-08 33.1 15.5 7.2e-06 25.5 2.1 4.1 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AJW71814.1 - 8.6e-05 22.2 2.5 8.6e-05 22.2 2.5 3.1 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Bactofilin PF04519.13 AJW71814.1 - 0.013 15.8 2.9 0.024 14.9 2.9 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal CTP_transf_3 PF02348.19 AJW71814.1 - 0.03 14.3 0.1 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 Cytidylyltransferase Fucokinase PF07959.12 AJW71814.1 - 0.034 13.1 1.2 0.07 12.1 1.2 1.5 1 0 0 1 1 1 0 L-fucokinase Capsule_synth PF05159.14 AJW71815.1 - 7.2e-12 45.4 0.6 1.1e-11 44.8 0.6 1.4 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein FERM_F2 PF18377.1 AJW71815.1 - 0.077 12.9 3.2 0.14 12.1 0.4 2.5 2 1 0 2 2 2 0 FERM F2 acyl-CoA binding protein-like domain Glyco_trans_1_4 PF13692.6 AJW71816.1 - 2.5e-12 47.4 0.0 4.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AJW71816.1 - 2.1e-05 24.8 0.0 9e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 BRCT PF00533.26 AJW71816.1 - 0.0039 17.5 0.1 0.014 15.7 0.1 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Glycos_transf_1 PF00534.20 AJW71816.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJW71816.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 GFO_IDH_MocA PF01408.22 AJW71817.1 - 2.3e-19 70.4 0.0 3.8e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 AJW71817.1 - 0.029 14.8 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AJW71817.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cupin_2 PF07883.11 AJW71818.1 - 1.7e-07 30.8 0.1 2.8e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AJW71818.1 - 6.1e-06 25.9 0.0 8.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Cupin FdtA PF05523.11 AJW71818.1 - 0.031 14.0 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal Cupin_3 PF05899.12 AJW71818.1 - 0.044 13.5 0.3 0.79 9.5 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 AJW71818.1 - 0.062 13.5 0.1 0.085 13.0 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family GDP_Man_Dehyd PF16363.5 AJW71819.1 - 8e-49 166.8 0.6 2.3e-48 165.3 0.6 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJW71819.1 - 8.8e-45 153.0 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AJW71819.1 - 1.8e-19 69.9 0.0 2.2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AJW71819.1 - 6.8e-12 45.0 0.4 1.2e-11 44.2 0.4 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AJW71819.1 - 1.3e-11 44.1 1.6 8.8e-08 31.6 0.1 2.6 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 AJW71819.1 - 4e-11 42.6 2.7 5.1e-09 35.7 2.7 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 AJW71820.1 - 1.9e-110 369.4 0.0 2.6e-110 368.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AJW71820.1 - 1.4e-56 191.7 0.0 2e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AJW71820.1 - 6.5e-06 25.5 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AJW71820.1 - 0.0028 16.7 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AJW71820.1 - 0.013 14.6 0.0 0.035 13.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 AJW71820.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RBD PF02196.15 AJW71820.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain GFO_IDH_MocA PF01408.22 AJW71821.1 - 1.9e-13 51.3 0.0 3.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AJW71821.1 - 1.7e-05 24.8 0.1 3.7e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain IlvN PF07991.12 AJW71821.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 AJW71821.1 - 0.072 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CoA_binding PF02629.19 AJW71821.1 - 0.094 13.4 0.2 0.21 12.3 0.2 1.6 1 0 0 1 1 1 0 CoA binding domain GARS_N PF02844.15 AJW71821.1 - 0.14 13.0 0.1 0.38 11.6 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain 2-Hacid_dh_C PF02826.19 AJW71821.1 - 0.15 11.4 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 AJW71821.1 - 0.28 11.5 1.9 0.54 10.6 0.1 2.4 3 1 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AJW71822.1 - 0.0071 15.9 0.1 0.0075 15.9 0.1 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 AJW71822.1 - 0.015 15.5 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 AJW71822.1 - 0.017 14.6 0.1 0.018 14.5 0.1 1.0 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 AJW71822.1 - 0.026 13.9 0.0 0.027 13.8 0.0 1.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AJW71822.1 - 0.028 14.3 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 AJW71822.1 - 0.15 12.0 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 AJW71823.1 - 8.4e-30 104.0 0.0 1.6e-29 103.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AJW71823.1 - 1.7e-19 70.1 0.1 6.9e-19 68.1 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase CTP_transf_3 PF02348.19 AJW71824.1 - 3.1e-24 86.1 0.0 3.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AJW71824.1 - 0.0058 17.0 0.0 0.0065 16.8 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Polysacc_synt_2 PF02719.15 AJW71825.1 - 1.8e-72 244.0 0.2 2.1e-72 243.7 0.2 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AJW71825.1 - 9.2e-25 87.5 0.0 7.3e-24 84.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AJW71825.1 - 2.2e-19 70.1 0.0 5.6e-18 65.4 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AJW71825.1 - 4.9e-18 65.1 0.1 7.3e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AJW71825.1 - 1.3e-10 40.9 1.1 3.5e-08 32.9 0.5 2.9 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 AJW71825.1 - 7.4e-08 32.5 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 AJW71825.1 - 9e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 AJW71825.1 - 3.3e-06 26.4 0.0 4.2e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AJW71825.1 - 0.0021 17.6 0.1 0.0084 15.7 0.0 1.8 1 1 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 AJW71825.1 - 0.014 15.7 0.2 0.033 14.4 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 AJW71825.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 AJW71825.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 AJW71825.1 - 0.034 14.2 0.6 0.069 13.2 0.1 1.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PglZ PF08665.12 AJW71825.1 - 0.088 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 PglZ domain MTS PF05175.14 AJW71825.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain eIF-1a PF01176.19 AJW71825.1 - 0.12 12.1 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 NeuB PF03102.14 AJW71826.1 - 9.7e-80 267.5 0.5 1.6e-79 266.8 0.5 1.3 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 AJW71826.1 - 4.1e-08 33.7 0.1 1.7e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 SAF domain ChapFlgA PF13144.6 AJW71826.1 - 0.071 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Epimerase_2 PF02350.19 AJW71827.1 - 3.5e-80 269.5 0.8 4e-80 269.3 0.8 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase MGDG_synth PF06925.11 AJW71827.1 - 0.0001 22.4 0.2 0.016 15.3 0.0 2.6 3 0 0 3 3 3 2 Monogalactosyldiacylglycerol (MGDG) synthase SurE PF01975.17 AJW71827.1 - 0.071 12.9 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Survival protein SurE Glycos_transf_1 PF00534.20 AJW71827.1 - 0.34 10.4 4.2 1.3 8.5 0.3 3.2 4 0 0 4 4 4 0 Glycosyl transferases group 1 MBOAT PF03062.19 AJW71828.1 - 4.9e-31 108.4 3.7 4.9e-31 108.4 3.7 3.2 2 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AJW71828.1 - 8.6e-05 22.7 1.7 8.6e-05 22.7 1.7 2.4 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family Prion_bPrPp PF11587.8 AJW71828.1 - 0.86 9.5 3.8 0.35 10.7 0.2 2.3 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal DltD PF04914.12 AJW71829.1 - 0.033 13.6 1.7 0.097 12.0 0.3 2.0 2 0 0 2 2 2 0 DltD protein Med25 PF11232.8 AJW71829.1 - 0.035 14.1 0.4 0.11 12.5 0.3 1.8 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Glycos_transf_1 PF00534.20 AJW71830.1 - 8.1e-35 119.9 0.1 1.4e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AJW71830.1 - 5.9e-26 91.5 0.0 9.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AJW71830.1 - 3.8e-19 69.3 0.0 2.2e-18 66.8 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AJW71830.1 - 6.6e-10 39.2 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AJW71830.1 - 6.7e-07 29.9 0.0 0.035 14.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 AJW71830.1 - 0.0012 18.5 0.1 0.0093 15.7 0.1 2.2 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 AJW71830.1 - 0.0021 18.1 0.3 0.072 13.1 0.4 3.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like Radical_SAM PF04055.21 AJW71831.1 - 2.8e-15 57.1 0.2 2.8e-15 57.1 0.2 2.5 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 AJW71831.1 - 2.4e-06 27.9 0.0 7.2e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AJW71831.1 - 3.6e-06 27.1 0.0 3.6e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain TrmB PF01978.19 AJW71832.1 - 4.3e-22 77.8 0.0 1.2e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 AJW71832.1 - 1.2e-05 24.7 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.10 AJW71832.1 - 5.1e-05 23.0 0.0 0.00052 19.8 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AJW71832.1 - 0.0025 17.3 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AJW71832.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 MarR family Penicillinase_R PF03965.16 AJW71832.1 - 0.022 15.1 0.0 0.069 13.5 0.0 1.8 2 0 0 2 2 2 0 Penicillinase repressor MarR_2 PF12802.7 AJW71832.1 - 0.038 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_9 PF08221.11 AJW71832.1 - 0.064 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain PheRS_DBD3 PF18553.1 AJW71832.1 - 0.087 13.1 0.0 0.41 11.0 0.0 2.1 2 0 0 2 2 2 0 PheRS DNA binding domain 3 PadR PF03551.14 AJW71832.1 - 0.098 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.20 AJW71832.1 - 0.11 12.8 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HTH_27 PF13463.6 AJW71832.1 - 0.12 12.9 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain Fe_dep_repr_C PF02742.15 AJW71833.1 - 4.4e-18 65.1 0.3 8.4e-18 64.2 0.3 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 AJW71833.1 - 7.3e-15 54.9 0.2 1.2e-14 54.2 0.2 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 AJW71833.1 - 5.2e-05 23.1 0.0 8.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AJW71833.1 - 0.00014 22.2 0.3 0.00026 21.3 0.1 1.6 2 0 0 2 2 1 1 Transcriptional regulator MarR_2 PF12802.7 AJW71833.1 - 0.00018 21.3 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AJW71833.1 - 0.00044 20.7 0.0 0.00072 20.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AJW71833.1 - 0.0013 18.5 0.2 0.0023 17.8 0.2 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.6 AJW71833.1 - 0.0029 17.6 0.2 0.0042 17.1 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_Crp_2 PF13545.6 AJW71833.1 - 0.0038 17.2 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_1 PF00126.27 AJW71833.1 - 0.0088 16.0 0.0 0.023 14.7 0.0 1.8 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AJW71833.1 - 0.012 15.5 0.6 0.025 14.5 0.0 1.8 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_37 PF13744.6 AJW71833.1 - 0.034 14.1 0.4 0.076 13.0 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_6 PF01418.17 AJW71833.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family NLPC_P60 PF00877.19 AJW71833.1 - 0.091 12.8 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 NlpC/P60 family TFIIE_beta PF02186.15 AJW71833.1 - 0.14 12.4 0.3 0.37 11.1 0.2 1.7 2 0 0 2 2 2 0 TFIIE beta subunit core domain IF2_N PF04760.15 AJW71833.1 - 0.35 10.7 2.3 0.46 10.3 0.1 2.3 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region UPF0047 PF01894.17 AJW71835.1 - 6.8e-36 122.9 0.0 8e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 eRF1_1 PF03463.15 AJW71837.1 - 4.3e-19 68.8 1.3 4.3e-19 68.8 1.3 1.8 2 1 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 AJW71837.1 - 1.8e-09 38.1 0.3 7.6e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 AJW71837.1 - 0.014 15.7 1.4 0.041 14.2 0.5 2.3 1 1 1 2 2 2 0 eRF1 domain 2 CutA1 PF03091.15 AJW71838.1 - 3.7e-30 103.7 3.3 4e-30 103.6 3.3 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Peptidase_M50 PF02163.22 AJW71839.1 - 1.4e-20 73.6 0.1 2.7e-09 36.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M50 PDZ_2 PF13180.6 AJW71839.1 - 1.5e-08 34.8 0.0 3.5e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AJW71839.1 - 1.7e-07 31.0 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AJW71839.1 - 0.007 16.7 0.4 0.018 15.4 0.3 1.7 2 0 0 2 2 2 1 PDZ domain ATP_bind_3 PF01171.20 AJW71840.1 - 3e-21 76.0 0.0 4.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 AJW71840.1 - 6.5e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 AJW71840.1 - 0.00049 20.2 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family OrfB_Zn_ribbon PF07282.11 AJW71840.1 - 0.066 13.2 0.7 0.066 13.2 0.7 3.0 3 1 0 3 3 3 0 Putative transposase DNA-binding domain C1_2 PF03107.16 AJW71840.1 - 3.1 8.2 14.2 1.6 9.1 2.5 3.4 3 0 0 3 3 3 0 C1 domain zf-C2H2_3 PF13878.6 AJW71840.1 - 3.6 7.5 6.9 75 3.3 0.1 3.3 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Acylphosphatase PF00708.18 AJW71842.1 - 2.2e-25 88.9 0.7 2.4e-25 88.7 0.7 1.0 1 0 0 1 1 1 1 Acylphosphatase Ribosomal_L2_C PF03947.18 AJW71843.1 - 6.6e-36 123.3 2.5 2.7e-35 121.3 2.7 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AJW71843.1 - 1.1e-08 35.0 0.0 3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain AAA PF00004.29 AJW71844.1 - 1.4e-99 329.7 0.0 3e-49 166.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 AJW71844.1 - 1e-29 102.5 0.2 3.1e-29 101.0 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 AJW71844.1 - 6e-22 77.2 0.2 2.4e-11 43.2 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 AJW71844.1 - 6.6e-16 58.9 0.0 4.5e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AJW71844.1 - 1.3e-15 58.2 0.1 6.1e-06 26.7 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 AJW71844.1 - 1.5e-14 54.1 0.0 7.6e-09 35.5 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AJW71844.1 - 1.3e-10 41.7 0.4 0.0025 18.1 0.0 3.9 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 AJW71844.1 - 3e-10 39.8 1.4 0.00014 21.2 0.0 2.8 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_33 PF13671.6 AJW71844.1 - 7.1e-10 39.2 0.0 0.0017 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AJW71844.1 - 1.5e-09 38.0 0.6 0.0012 18.9 0.1 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AJW71844.1 - 7.9e-09 35.6 0.0 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 AJW71844.1 - 1.5e-08 34.3 0.1 3.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 AJW71844.1 - 7.6e-08 32.3 0.0 0.0076 16.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 AJW71844.1 - 2.3e-07 30.7 0.1 0.039 13.6 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 AJW71844.1 - 1.5e-06 28.5 0.0 0.045 14.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Bac_DnaA PF00308.18 AJW71844.1 - 2.3e-06 27.6 0.0 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_7 PF12775.7 AJW71844.1 - 2.9e-06 26.9 0.0 0.035 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 AJW71844.1 - 3.5e-06 27.4 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 AJW71844.1 - 3.5e-06 27.0 0.1 0.094 12.7 0.0 2.6 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 AJW71844.1 - 4e-06 26.3 2.0 0.12 11.7 0.0 3.9 3 1 1 4 4 4 2 KaiC AAA_18 PF13238.6 AJW71844.1 - 4.4e-06 27.3 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AJW71844.1 - 7.3e-06 25.5 0.8 0.039 13.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AJW71844.1 - 9.1e-06 25.5 0.0 0.035 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 AJW71844.1 - 2.6e-05 23.8 0.2 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 AJW71844.1 - 7.7e-05 22.7 0.1 0.68 9.8 0.0 3.3 4 0 0 4 4 4 2 NACHT domain ABC_tran PF00005.27 AJW71844.1 - 8.8e-05 23.0 0.0 0.8 10.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ATPase_2 PF01637.18 AJW71844.1 - 0.00011 22.2 0.0 0.063 13.2 0.0 3.4 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 AJW71844.1 - 0.00015 21.0 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NB-ARC PF00931.22 AJW71844.1 - 0.00015 21.1 0.0 0.44 9.7 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 AJW71844.1 - 0.00022 20.6 0.6 0.15 11.3 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin AAA_30 PF13604.6 AJW71844.1 - 0.00055 19.7 0.2 1.6 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 AJW71844.1 - 0.00061 19.7 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 AJW71844.1 - 0.0007 19.4 0.1 0.68 9.6 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase DUF2075 PF09848.9 AJW71844.1 - 0.001 18.4 0.0 0.39 9.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 AJW71844.1 - 0.0015 17.7 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 AJW71844.1 - 0.0017 18.0 6.4 1.3 8.5 0.2 3.8 2 2 1 3 3 3 1 AAA domain AAA_11 PF13086.6 AJW71844.1 - 0.0029 17.5 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 AJW71844.1 - 0.005 16.9 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 AJW71844.1 - 0.0093 15.4 0.0 4.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein CPT PF07931.12 AJW71844.1 - 0.0097 15.8 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 AJW71844.1 - 0.014 15.1 0.2 2.9 7.7 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 AJW71844.1 - 0.015 15.0 0.1 12 5.6 0.0 3.6 3 1 1 4 4 3 0 Guanylate kinase ResIII PF04851.15 AJW71844.1 - 0.015 15.3 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AJW71844.1 - 0.018 15.4 2.0 4 7.8 0.1 3.6 3 1 1 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 AJW71844.1 - 0.018 14.7 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 AJW71844.1 - 0.02 14.8 2.0 10 6.0 0.0 3.8 3 1 1 4 4 3 0 NTPase AAA_17 PF13207.6 AJW71844.1 - 0.023 15.1 0.0 1.2 9.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AJW71844.1 - 0.031 13.3 0.0 8.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 AJW71844.1 - 0.044 12.7 0.0 8.4 5.2 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Viral_helicase1 PF01443.18 AJW71844.1 - 0.05 13.3 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 AJW71844.1 - 0.051 13.3 0.0 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Vps4_C PF09336.10 AJW71844.1 - 0.069 13.2 0.7 9 6.4 0.1 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PIF1 PF05970.14 AJW71844.1 - 0.086 12.0 0.0 9.3 5.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Rad17 PF03215.15 AJW71844.1 - 0.12 12.2 0.0 44 3.9 0.0 3.0 2 1 1 3 3 3 0 Rad17 P-loop domain IPT PF01745.16 AJW71844.1 - 0.17 11.2 0.2 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.11 AJW71844.1 - 0.22 11.6 0.1 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Torsin GatB_N PF02934.15 AJW71845.1 - 5e-63 213.1 0.1 5e-63 213.1 0.1 1.8 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AJW71845.1 - 1e-18 67.6 10.3 2.8e-18 66.2 10.3 1.8 1 0 0 1 1 1 1 GatB domain GAD PF02938.14 AJW71845.1 - 1.7e-07 31.4 0.1 7.5e-07 29.3 0.1 2.2 1 0 0 1 1 1 1 GAD domain DUF2202 PF09968.9 AJW71845.1 - 0.12 12.2 5.5 0.91 9.4 5.3 2.5 1 1 1 2 2 2 0 Uncharacterized protein domain (DUF2202) zf-LITAF-like PF10601.9 AJW71846.1 - 0.069 13.4 0.2 0.099 12.9 0.2 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Imm5 PF14423.6 AJW71846.1 - 0.084 13.1 0.2 0.084 13.1 0.2 1.0 1 0 0 1 1 1 0 Immunity protein Imm5 NT5C PF06941.12 AJW71847.1 - 5e-13 49.3 1.4 5.8e-13 49.1 1.4 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DnaJ_C PF01556.18 AJW71848.1 - 3.3e-37 127.8 0.6 4.3e-37 127.5 0.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AJW71848.1 - 4.1e-27 94.1 2.5 6.5e-27 93.4 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AJW71848.1 - 5.2e-14 52.4 21.6 1e-13 51.4 21.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AJW71848.1 - 0.0017 18.3 20.4 0.071 13.1 6.0 3.4 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein HSP70 PF00012.20 AJW71849.1 - 3.1e-214 712.6 17.4 7.6e-193 642.0 13.4 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 AJW71849.1 - 1e-17 64.0 5.3 1e-17 64.0 5.3 2.4 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 AJW71849.1 - 0.00015 21.5 0.1 0.00035 20.4 0.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Lipoprotein_10 PF03202.13 AJW71849.1 - 0.32 11.4 4.3 0.66 10.4 4.3 1.5 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region GrpE PF01025.19 AJW71850.1 - 2.5e-38 131.3 3.6 3.1e-38 131.0 3.6 1.0 1 0 0 1 1 1 1 GrpE PhaP_Bmeg PF09602.10 AJW71850.1 - 0.024 14.6 3.1 0.031 14.2 3.1 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Retrotrans_gag PF03732.17 AJW71850.1 - 0.044 14.1 0.3 0.07 13.4 0.3 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Succ_DH_flav_C PF02910.20 AJW71850.1 - 0.074 13.0 0.1 0.9 9.5 0.0 2.1 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term BST2 PF16716.5 AJW71850.1 - 0.17 12.5 3.2 0.38 11.4 3.3 1.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4404 PF14357.6 AJW71850.1 - 0.24 12.1 2.1 0.54 10.9 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Ribosomal_S6 PF01250.17 AJW71850.1 - 0.24 11.7 1.6 3.2 8.1 0.3 2.8 2 2 0 2 2 2 0 Ribosomal protein S6 DUF3783 PF12646.7 AJW71851.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) DFP PF04127.15 AJW71851.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF354 PF04007.12 AJW71852.1 - 9.8e-44 149.8 9.0 1.1e-43 149.6 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) ORF45 PF17620.2 AJW71852.1 - 0.0018 18.4 0.3 0.0095 16.1 0.2 2.1 2 1 0 2 2 2 1 Family of unknown function LpxB PF02684.15 AJW71852.1 - 0.0025 16.7 0.3 0.0034 16.3 0.3 1.3 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase ABC2_membrane PF01061.24 AJW71853.1 - 7.8e-20 71.2 21.1 7.8e-20 71.2 21.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AJW71853.1 - 2e-13 50.2 26.2 2e-13 50.2 26.2 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AJW71853.1 - 0.008 16.2 10.2 0.008 16.2 10.2 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AJW71853.1 - 0.015 14.6 19.9 0.025 13.9 19.9 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3493 PF11998.8 AJW71853.1 - 0.11 12.7 0.8 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 ABC_tran PF00005.27 AJW71854.1 - 2.6e-28 99.2 0.0 4.4e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AJW71854.1 - 8.5e-13 48.8 0.0 1.1e-06 28.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AJW71854.1 - 9.4e-06 26.3 1.1 3.2e-05 24.6 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 AJW71854.1 - 2.6e-05 24.1 0.1 0.0013 18.5 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AJW71854.1 - 0.01 15.6 0.2 0.02 14.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AJW71854.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 AJW71854.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AJW71854.1 - 0.096 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase Glyco_hydro_56 PF01630.18 AJW71854.1 - 0.16 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Hyaluronidase MeaB PF03308.16 AJW71854.1 - 0.18 10.8 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 AJW71854.1 - 0.2 11.1 1.4 14 5.0 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AJW71854.1 - 0.37 11.3 7.4 1.2 9.6 7.4 2.2 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 AJW71854.1 - 0.4 10.7 5.2 5.1 7.1 0.2 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain tRNA_anti-codon PF01336.25 AJW71855.1 - 5.8e-14 51.8 0.1 0.0029 17.6 0.0 3.8 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 AJW71855.1 - 3.3e-09 36.8 0.0 1.4e-05 24.9 0.0 2.9 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 REPA_OB_2 PF16900.5 AJW71855.1 - 3.1e-07 30.2 0.4 0.55 10.2 0.0 3.4 3 0 0 3 3 3 3 Replication protein A OB domain POT1PC PF16686.5 AJW71855.1 - 0.00022 21.1 0.0 1.3 8.9 0.0 3.2 3 0 0 3 3 3 2 ssDNA-binding domain of telomere protection protein DEAD PF00270.29 AJW71856.1 - 1.1e-37 129.5 0.2 3e-37 128.1 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_assoc PF08494.11 AJW71856.1 - 3.4e-26 92.2 0.0 7.4e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/H associated Helicase_C PF00271.31 AJW71856.1 - 6.1e-22 78.1 0.3 5.5e-18 65.3 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 AJW71856.1 - 6e-13 49.1 0.5 1.4e-12 47.9 0.5 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 AJW71856.1 - 0.00013 20.8 0.0 0.00022 20.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.6 AJW71856.1 - 0.0053 17.1 0.1 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain HypA PF01155.19 AJW71856.1 - 0.037 14.0 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytadhesin_P30 PF07271.11 AJW71856.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 MH1 PF03165.16 AJW71856.1 - 0.079 13.2 1.4 0.28 11.4 0.5 2.3 2 0 0 2 2 2 0 MH1 domain Zn-ribbon_8 PF09723.10 AJW71856.1 - 0.2 11.8 0.1 0.42 10.8 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain AAA_11 PF13086.6 AJW71856.1 - 0.21 11.4 0.6 0.76 9.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain Synaphin PF05835.12 AJW71856.1 - 0.22 11.8 1.3 0.52 10.6 1.3 1.6 1 0 0 1 1 1 0 Synaphin protein Zn_ribbon_SprT PF17283.2 AJW71856.1 - 0.29 11.1 1.1 0.62 10.0 1.1 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DUF3741 PF12552.8 AJW71856.1 - 0.39 10.7 1.8 4.5 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) PEP-CTERM PF07589.11 AJW71857.1 - 0.24 11.5 0.1 0.24 11.5 0.1 1.5 2 0 0 2 2 2 0 PEP-CTERM motif Rad51 PF08423.11 AJW71858.1 - 9.4e-32 110.3 0.1 1.1e-31 110.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 AJW71858.1 - 2.2e-13 50.1 2.7 3.8e-12 46.1 2.7 2.1 1 1 0 1 1 1 1 KaiC RecA PF00154.21 AJW71858.1 - 5.6e-09 35.9 0.0 6.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 AJW71858.1 - 3.1e-06 27.1 0.1 5.6e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AJW71858.1 - 9.2e-05 22.9 0.1 0.00014 22.3 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 AJW71858.1 - 0.00058 19.6 0.1 0.0007 19.3 0.1 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) ABC_tran PF00005.27 AJW71858.1 - 0.0017 18.9 1.7 0.0021 18.6 1.4 1.5 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 AJW71858.1 - 0.0032 17.1 0.0 0.035 13.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AJW71858.1 - 0.0041 17.1 1.6 0.0089 16.0 1.6 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 AJW71858.1 - 0.011 15.5 0.1 0.026 14.2 0.0 1.7 1 1 1 2 2 2 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 AJW71858.1 - 0.02 13.8 0.1 0.033 13.1 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CobA_CobO_BtuR PF02572.15 AJW71858.1 - 0.077 13.2 0.2 0.43 10.8 0.1 2.0 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_22 PF13401.6 AJW71858.1 - 0.15 12.4 0.3 0.42 10.9 0.3 1.7 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 AJW71858.1 - 0.47 9.6 6.1 0.45 9.6 0.6 2.1 2 0 0 2 2 2 0 PAXNEB protein LSM PF01423.22 AJW71859.1 - 5.6e-20 70.8 1.7 6.3e-20 70.6 1.7 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 AJW71859.1 - 0.0095 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Hfq protein BrnA_antitoxin PF14384.6 AJW71859.1 - 0.065 13.7 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system S-AdoMet_synt_C PF02773.16 AJW71860.1 - 2.3e-71 238.2 0.0 2.7e-70 234.7 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AJW71860.1 - 4.2e-48 162.6 0.3 6.2e-47 158.8 0.0 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AJW71860.1 - 2.3e-40 137.3 1.1 7.7e-40 135.6 0.2 2.3 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 AJW71860.1 - 0.00018 20.4 2.9 0.034 12.9 0.5 2.2 1 1 1 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) Epimerase PF01370.21 AJW71861.1 - 6.3e-14 52.0 0.1 9.5e-13 48.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AJW71861.1 - 1.5e-11 44.5 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AJW71861.1 - 1.5e-08 34.0 1.6 1.6e-06 27.4 1.5 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AJW71861.1 - 1.6e-08 34.4 3.3 3.4e-08 33.3 3.3 1.5 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 AJW71861.1 - 2.3e-05 23.6 0.0 0.049 12.7 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 AJW71861.1 - 3.5e-05 23.1 0.3 0.0079 15.4 0.0 2.8 1 1 1 3 3 3 1 Male sterility protein CbiD PF01888.17 AJW71862.1 - 1.9e-91 305.8 3.5 2.4e-91 305.5 3.5 1.1 1 0 0 1 1 1 1 CbiD DUF3042 PF11240.8 AJW71862.1 - 0.1 12.6 1.8 0.69 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) CbiG_N PF11760.8 AJW71863.1 - 4.3e-33 113.2 0.2 6.9e-33 112.5 0.2 1.3 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.16 AJW71863.1 - 5.4e-26 91.4 0.2 1.1e-25 90.5 0.0 1.6 2 0 0 2 2 2 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.8 AJW71863.1 - 5.9e-16 58.3 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis central region SpoU_sub_bind PF08032.12 AJW71863.1 - 0.0016 18.7 0.0 0.0058 16.9 0.0 1.9 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding CbiX PF01903.17 AJW71864.1 - 3.1e-34 117.5 0.0 6e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 AJW71864.1 - 1.3e-06 27.9 0.9 1.7e-06 27.6 0.9 1.3 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 AJW71864.1 - 2.7e-05 23.4 0.1 0.0032 16.6 0.1 2.0 1 1 0 1 1 1 1 Ferrochelatase CbiC PF02570.15 AJW71865.1 - 1.1e-70 237.3 0.7 1.2e-70 237.2 0.7 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase MCR_C PF04609.12 AJW71865.1 - 0.019 14.0 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C GATase_3 PF07685.14 AJW71866.1 - 2.9e-43 147.8 0.1 4.1e-43 147.3 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AJW71866.1 - 1.6e-17 63.7 1.2 2.8e-17 63.0 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AJW71866.1 - 2.1e-15 57.1 1.0 1e-09 38.5 0.0 2.9 2 1 1 3 3 3 2 AAA domain SNO PF01174.19 AJW71866.1 - 1.9e-05 24.6 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family CTP_synth_N PF06418.14 AJW71866.1 - 0.0084 15.5 1.2 0.016 14.5 0.1 1.9 2 0 0 2 2 2 1 CTP synthase N-terminus ATLF PF07737.11 AJW71866.1 - 0.098 11.9 0.2 0.098 11.9 0.2 2.6 2 1 0 3 3 3 0 Anthrax toxin lethal factor, N- and C-terminal domain Beta_helix_2 PF18835.1 AJW71866.1 - 0.12 12.2 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase DJ-1_PfpI PF01965.24 AJW71866.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family CobA_CobO_BtuR PF02572.15 AJW71867.1 - 1.4e-62 210.9 0.3 1.6e-62 210.8 0.3 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_25 PF13481.6 AJW71867.1 - 0.011 15.3 0.1 0.025 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AJW71867.1 - 0.016 15.0 0.5 0.035 13.8 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AJW71867.1 - 0.034 14.2 0.9 0.058 13.4 0.9 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 AJW71867.1 - 0.049 13.7 2.0 0.73 9.9 0.4 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 AJW71867.1 - 0.078 13.4 0.7 0.13 12.7 0.7 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 AJW71867.1 - 0.079 12.1 0.5 3.6 6.7 0.3 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase EIF_2_alpha PF07541.12 AJW71868.1 - 2.3e-17 63.2 0.8 4.8e-17 62.1 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 AJW71868.1 - 1.6e-10 41.2 0.1 5.1e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 AJW71868.1 - 0.023 14.7 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 S1 domain Arm-DNA-bind_2 PF12167.8 AJW71868.1 - 0.07 13.1 0.7 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Arm DNA-binding domain Nop10p PF04135.12 AJW71869.1 - 7.2e-24 83.6 3.8 7.5e-24 83.5 3.8 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PolC_DP2 PF03833.13 AJW71869.1 - 0.002 16.1 0.8 0.002 16.1 0.8 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 RecR PF02132.15 AJW71869.1 - 0.024 14.2 2.5 0.028 14.0 2.5 1.2 1 0 0 1 1 1 0 RecR protein STT3 PF02516.14 AJW71870.1 - 2.5e-30 105.9 50.9 2.4e-26 92.7 22.9 3.2 2 1 1 3 3 3 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 AJW71870.1 - 6.4e-05 23.2 12.1 6.4e-05 23.2 12.1 3.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PBP PF01161.20 AJW71871.1 - 3.1e-36 124.6 0.0 3.5e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PIN_9 PF18477.1 AJW71872.1 - 4.1e-15 56.1 0.1 4.9e-15 55.8 0.1 1.0 1 0 0 1 1 1 1 PIN like domain PIN_12 PF16289.5 AJW71872.1 - 0.00019 22.0 3.0 0.00025 21.6 3.0 1.2 1 0 0 1 1 1 1 PIN domain PIN_4 PF13638.6 AJW71872.1 - 0.0023 18.2 1.5 0.0032 17.7 1.5 1.3 1 1 0 1 1 1 1 PIN domain Fcf1 PF04900.12 AJW71872.1 - 0.012 16.0 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Fcf1 YfdX PF10938.8 AJW71872.1 - 0.055 13.4 0.1 0.061 13.3 0.1 1.1 1 0 0 1 1 1 0 YfdX protein GTP_EFTU PF00009.27 AJW71873.1 - 2.6e-30 105.4 0.1 8.6e-30 103.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 AJW71873.1 - 1.9e-26 92.1 0.7 1.7e-25 89.1 0.2 2.6 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal MMR_HSR1 PF01926.23 AJW71873.1 - 1.5e-05 25.0 0.0 4.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AJW71873.1 - 2.9e-05 24.3 0.8 7.2e-05 23.1 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 AJW71873.1 - 0.0026 17.7 0.3 0.08 12.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 AJW71873.1 - 0.015 15.3 0.0 0.075 13.0 0.0 2.0 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 AJW71873.1 - 0.036 13.6 0.4 2 7.9 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B NOB1_Zn_bind PF08772.11 AJW71873.1 - 0.047 13.9 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like ILEI PF15711.5 AJW71873.1 - 0.14 12.7 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Interleukin-like EMT inducer HypA PF01155.19 AJW71873.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S6e PF01092.19 AJW71874.1 - 2.2e-26 92.3 0.3 2.7e-26 92.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e IBR PF01485.21 AJW71875.1 - 0.0013 18.9 1.6 0.0019 18.4 1.3 1.3 1 1 0 1 1 1 1 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 AJW71875.1 - 0.0021 17.9 3.3 0.015 15.2 3.3 2.0 1 1 0 1 1 1 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AJW71875.1 - 0.0082 16.0 0.8 0.012 15.6 0.8 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain CpXC PF14353.6 AJW71875.1 - 0.0092 16.0 2.5 0.028 14.5 0.0 2.0 1 1 1 2 2 2 1 CpXC protein YacG PF03884.14 AJW71875.1 - 0.011 15.4 0.3 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Ribosomal_S27e PF01667.17 AJW71875.1 - 0.024 14.3 3.8 0.41 10.4 4.3 2.0 1 1 1 2 2 2 0 Ribosomal protein S27 zf-H2C2_5 PF13909.6 AJW71875.1 - 0.03 14.1 0.7 0.03 14.1 0.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PhnA_Zn_Ribbon PF08274.12 AJW71875.1 - 0.033 14.2 4.0 0.27 11.2 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon UPF0547 PF10571.9 AJW71875.1 - 0.06 13.4 4.4 3.1 8.0 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HypA PF01155.19 AJW71875.1 - 0.062 13.3 0.2 0.064 13.3 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 AJW71875.1 - 0.078 12.5 2.8 3.3 7.3 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Prok-RING_1 PF14446.6 AJW71875.1 - 0.1 12.6 3.3 0.13 12.2 3.3 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2H2_4 PF13894.6 AJW71875.1 - 0.11 13.4 2.5 2.1 9.4 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 AJW71875.1 - 0.23 11.8 3.9 0.79 10.1 0.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 AJW71875.1 - 0.27 11.5 6.6 13 6.1 7.1 2.2 1 1 1 2 2 2 0 zinc-ribbon zf-ISL3 PF14690.6 AJW71875.1 - 0.29 11.8 2.3 6.5 7.5 0.2 2.1 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 AJW71875.1 - 0.36 10.3 7.0 11 5.6 7.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-ACC PF17848.1 AJW71875.1 - 0.37 10.9 6.1 4.3 7.5 0.3 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF2197 PF09963.9 AJW71875.1 - 0.45 10.8 3.5 2.6 8.4 2.7 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn-ribbon_8 PF09723.10 AJW71875.1 - 1.6 8.9 6.1 22 5.3 0.8 2.1 1 1 1 2 2 2 0 Zinc ribbon domain TPR_1 PF00515.28 AJW71876.1 - 1.1e-17 63.0 14.7 2.1e-09 36.8 0.9 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AJW71876.1 - 6.1e-16 57.2 7.5 8e-08 31.8 0.2 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 AJW71876.1 - 9.1e-13 47.3 15.1 4e-07 29.7 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 AJW71876.1 - 1.3e-12 47.2 6.0 0.0005 20.3 0.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 AJW71876.1 - 1.4e-09 38.1 1.2 0.00012 22.3 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AJW71876.1 - 1.2e-07 32.0 0.0 0.087 13.7 0.0 3.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AJW71876.1 - 2.6e-07 30.2 0.3 0.00078 19.3 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AJW71876.1 - 4.6e-07 30.2 0.7 0.016 15.7 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 AJW71876.1 - 1.4e-06 28.3 0.0 3.8e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 AJW71876.1 - 8.2e-06 25.5 0.0 0.004 17.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 AJW71876.1 - 1.9e-05 24.2 8.1 0.036 13.8 2.8 3.4 2 1 1 3 3 3 2 TPR repeat Peptidase_C39_2 PF13529.6 AJW71876.1 - 2.5e-05 24.8 0.1 0.00011 22.8 0.0 2.0 2 1 0 2 2 2 1 Peptidase_C39 like family TPR_16 PF13432.6 AJW71876.1 - 0.00025 21.6 0.0 0.0024 18.5 0.0 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AJW71876.1 - 0.0026 18.3 1.7 3.4 8.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_C39 PF03412.15 AJW71876.1 - 0.0085 15.9 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase C39 family Peptidase_C70 PF12385.8 AJW71876.1 - 0.069 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Fis1_TPR_C PF14853.6 AJW71876.1 - 0.14 12.3 1.8 6.3 6.9 0.1 2.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat GATase PF00117.28 AJW71877.1 - 7.6e-21 74.7 0.0 8.8e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AJW71877.1 - 2.1e-08 34.2 0.0 1.9e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AJW71877.1 - 0.023 14.5 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 SNO glutamine amidotransferase family UPF0182 PF03699.13 AJW71878.1 - 5.5e-32 110.8 14.2 6.7e-31 107.2 14.2 2.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) DNA_primase_S PF01896.19 AJW71879.1 - 6.7e-16 58.8 1.0 4.4e-15 56.2 1.0 2.1 1 1 0 1 1 1 1 DNA primase small subunit PolC_DP2 PF03833.13 AJW71879.1 - 0.13 10.1 4.2 0.18 9.6 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DNA_primase_lrg PF04104.14 AJW71880.1 - 3.3e-24 85.7 0.0 8.4e-24 84.4 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Med5 PF08689.10 AJW71880.1 - 0.00093 17.2 0.1 0.0011 16.9 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 AP_endonuc_2 PF01261.24 AJW71881.1 - 6e-34 117.3 0.0 1.1e-33 116.5 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel HGTP_anticodon PF03129.20 AJW71882.1 - 7.7e-18 64.4 0.5 2.8e-17 62.6 0.4 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AJW71882.1 - 9.6e-12 45.2 0.4 2.6e-10 40.6 0.4 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-RRPl_C4 PF17026.5 AJW71882.1 - 0.036 14.2 0.4 0.5 10.5 0.1 2.6 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 AJW71882.1 - 0.055 14.2 1.1 0.29 11.9 0.8 2.3 1 1 1 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 AJW71882.1 - 0.098 12.8 0.2 18 5.6 0.0 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 AJW71882.1 - 0.12 12.3 3.4 7 6.7 0.4 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 AJW71882.1 - 0.13 12.0 6.6 0.61 9.9 0.8 3.0 3 0 0 3 3 3 0 zinc-ribbon domain HemolysinCabind PF00353.19 AJW71883.1 - 7.9e-28 96.1 126.7 3.4e-08 33.3 15.2 9.8 6 1 5 12 12 12 6 RTX calcium-binding nonapeptide repeat (4 copies) PA14 PF07691.12 AJW71883.1 - 9.6e-11 41.7 0.0 3.7e-10 39.8 0.0 2.1 1 0 0 1 1 1 1 PA14 domain Big_9 PF17963.1 AJW71883.1 - 5.9e-08 33.3 3.8 5.9e-08 33.3 3.8 9.8 3 2 1 5 5 5 1 Bacterial Ig domain ESCRT-II PF05871.12 AJW71884.1 - 3.7e-08 33.7 4.9 8.4 6.6 0.0 6.4 1 1 6 7 7 7 6 ESCRT-II complex subunit YozE_SAM_like PF06855.12 AJW71884.1 - 7.2e-05 22.9 0.0 2.3e+02 2.0 0.0 6.3 1 1 6 7 7 7 0 YozE SAM-like fold EF-hand_6 PF13405.6 AJW71884.1 - 0.41 10.7 31.7 53 4.1 0.2 8.3 8 0 0 8 8 8 0 EF-hand domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopumilus_sp._NF5-ASM95617v1/GCA_000956175.1_ASM95617v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopumilus_sp._NF5-ASM95617v1/GCA_000956175.1_ASM95617v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopumilus_sp._NF5-ASM95617v1/GCA_000956175.1_ASM95617v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosopumilus_sp._NF5-ASM95617v1/GCA_000956175.1_ASM95617v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 16:23:47 2019 # [ok]