# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PA_decarbox PF05870.6 EGG41049.1 - 0.028 13.8 0.2 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 Phenolic acid decarboxylase (PAD) SNO PF01174.14 EGG41050.1 - 4.4e-50 169.9 0.1 5.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGG41050.1 - 6.4e-13 48.5 0.0 1.1e-12 47.7 0.0 1.4 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EGG41050.1 - 2.1e-12 46.9 0.0 3.3e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG41050.1 - 1.5e-07 31.1 0.0 1.5e-06 27.7 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EGG41050.1 - 4.6e-07 29.3 0.0 6.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 EGG41050.1 - 2.4e-06 27.3 0.1 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 EGG41050.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase SOR_SNZ PF01680.12 EGG41051.1 - 1.1e-91 306.0 3.0 1.5e-91 305.6 2.1 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EGG41051.1 - 3.3e-07 29.6 1.7 1.1e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EGG41051.1 - 6.1e-05 22.3 0.4 0.016 14.4 0.0 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EGG41051.1 - 0.00054 19.0 0.0 0.005 15.9 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 EGG41051.1 - 0.00089 18.1 0.2 0.76 8.5 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.10 EGG41051.1 - 0.0032 16.6 5.6 0.055 12.6 0.2 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase OMPdecase PF00215.19 EGG41051.1 - 0.0083 15.5 0.5 0.83 8.9 0.0 2.5 2 1 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.9 EGG41051.1 - 0.017 14.0 2.9 0.61 9.0 0.0 3.3 2 2 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase PcrB PF01884.12 EGG41051.1 - 0.018 14.3 0.1 0.04 13.1 0.1 1.7 1 0 0 1 1 1 0 PcrB family Aconitase PF00330.15 EGG41053.1 - 1.5e-152 508.3 0.1 1.6e-151 504.9 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGG41053.1 - 2.2e-36 124.8 0.1 5.8e-36 123.4 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.8 EGG41053.1 - 0.013 14.0 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) AsnC_trans_reg PF01037.16 EGG41056.1 - 2e-11 43.4 0.0 2.3e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 AsnC family EVE PF01878.13 EGG41057.1 - 1.8e-35 122.0 0.3 2e-35 121.9 0.2 1.0 1 0 0 1 1 1 1 EVE domain DUF1175 PF06672.6 EGG41057.1 - 0.026 13.8 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) CRF1 PF10380.4 EGG41057.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 B5 PF03484.10 EGG41060.1 - 1.3e-20 72.9 0.1 2.1e-14 53.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.12 EGG41060.1 - 2.1e-12 46.8 0.3 3.7e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA-synt_2d PF01409.15 EGG41061.1 - 4.6e-84 281.4 0.0 7.2e-84 280.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EGG41061.1 - 8.9e-06 24.6 0.3 0.00077 18.3 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EGG41061.1 - 0.00047 19.7 0.2 0.00098 18.7 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Mer2 PF09074.5 EGG41061.1 - 0.015 15.1 1.5 0.029 14.3 1.1 1.4 1 0 0 1 1 1 0 Mer2 HTH_24 PF13412.1 EGG41061.1 - 0.041 13.2 2.6 0.18 11.2 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding tRNA-synt_1b PF00579.20 EGG41062.1 - 4.1e-30 104.9 0.0 6.4e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 EGG41062.1 - 0.024 13.3 0.1 0.27 9.8 0.0 2.2 1 1 0 2 2 2 0 tRNA synthetases class I (K) RNA_bind_2 PF10133.4 EGG41063.1 - 0.11 12.5 1.7 0.18 11.8 0.2 1.9 2 0 0 2 2 2 0 Predicted RNA-binding protein zinc_ribbon_6 PF14599.1 EGG41065.1 - 0.08 12.7 19.1 0.58 9.9 1.9 4.0 4 2 0 4 4 4 0 Zinc-ribbon Apidaecin PF00807.12 EGG41065.1 - 0.14 11.9 0.6 22 4.8 0.0 2.5 2 0 0 2 2 2 0 Apidaecin DZR PF12773.2 EGG41065.1 - 0.18 11.6 20.6 6.4 6.6 2.7 4.0 3 1 0 3 3 3 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 EGG41065.1 - 0.48 9.9 17.0 2.3 7.7 1.4 4.2 3 2 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Molybdop_Fe4S4 PF04879.11 EGG41065.1 - 1.9 8.3 11.5 2.5 7.9 0.3 2.9 3 0 0 3 3 3 0 Molybdopterin oxidoreductase Fe4S4 domain Lar_restr_allev PF14354.1 EGG41065.1 - 2.6 8.4 15.8 51 4.2 0.0 5.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar Baculo_RING PF05883.6 EGG41065.1 - 4 7.2 10.9 1.8 8.3 0.9 2.8 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain Ribosomal_L37e PF01907.14 EGG41065.1 - 6.2 6.6 7.9 6.1 6.7 0.0 3.7 3 0 0 3 3 3 0 Ribosomal protein L37e C1_1 PF00130.17 EGG41065.1 - 8.5 6.1 20.5 1.9 8.3 2.0 3.3 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3997 PF13162.1 EGG41066.1 - 0.019 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) CTP_transf_2 PF01467.21 EGG41067.1 - 3.3e-12 46.7 0.0 1.5e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EGG41067.1 - 0.019 14.6 0.2 0.038 13.6 0.1 1.7 2 1 0 2 2 2 0 FAD synthetase Wzt_C PF14524.1 EGG41068.1 - 0.005 16.5 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 Wzt C-terminal domain OapA PF04225.7 EGG41068.1 - 0.047 13.5 0.1 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 Opacity-associated protein A LysM-like domain AhpC-TSA PF00578.16 EGG41071.1 - 1.4e-21 76.4 0.4 1.8e-21 76.1 0.3 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG41071.1 - 7.8e-13 48.1 0.1 1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EGG41071.1 - 8.4e-09 35.4 0.7 1.6e-08 34.5 0.5 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGG41071.1 - 6.9e-08 32.6 0.2 1e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 EGG41071.1 - 0.013 15.1 0.4 0.74 9.5 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin T4_deiodinase PF00837.12 EGG41071.1 - 0.015 14.3 0.0 0.02 13.8 0.0 1.3 1 1 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_3 PF13192.1 EGG41071.1 - 0.036 13.8 0.4 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin domain HTH_24 PF13412.1 EGG41072.1 - 7e-06 25.3 0.1 6.1e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 EGG41072.1 - 1e-05 25.0 0.0 4.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain B12-binding_2 PF02607.12 EGG41072.1 - 6.4e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain HTH_23 PF13384.1 EGG41072.1 - 0.00013 21.5 0.0 0.00046 19.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.7 EGG41072.1 - 0.00014 21.3 0.0 0.00037 20.0 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.1 EGG41072.1 - 0.0014 18.5 0.0 0.0056 16.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Wzz PF02706.10 EGG41072.1 - 0.0078 16.0 1.2 4.8 7.0 0.1 2.7 2 1 0 2 2 2 2 Chain length determinant protein TrmB PF01978.14 EGG41072.1 - 0.018 14.6 0.1 0.21 11.2 0.0 2.5 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 EGG41072.1 - 0.021 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix MarR PF01047.17 EGG41072.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 MarR family KorB PF08535.5 EGG41072.1 - 0.022 14.9 0.0 0.15 12.2 0.0 2.3 2 1 0 2 2 2 0 KorB domain RPA_C PF08784.6 EGG41072.1 - 0.12 12.8 0.0 7.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Replication protein A C terminal HTH_6 PF01418.12 EGG41072.1 - 0.21 11.3 1.8 3.8 7.3 0.0 3.0 2 1 2 4 4 4 0 Helix-turn-helix domain, rpiR family DDE_Tnp_IS240 PF13610.1 EGG41073.1 - 1.5e-23 83.3 0.8 2.4e-23 82.6 0.6 1.3 1 0 0 1 1 1 1 DDE domain rve PF00665.21 EGG41073.1 - 1.8e-08 34.4 0.1 3.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS66 PF03050.9 EGG41073.1 - 1.2e-06 27.9 0.1 1.5e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Transposase IS66 family rve_3 PF13683.1 EGG41073.1 - 2.6e-06 26.8 0.2 1.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Transposase_mut PF00872.13 EGG41073.1 - 0.0069 14.9 0.6 0.88 8.0 0.1 2.2 2 0 0 2 2 2 2 Transposase, Mutator family Alpha-amylase_N PF02903.9 EGG41073.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain HTH_23 PF13384.1 EGG41073.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Rieske PF00355.21 EGG41074.1 - 0.1 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain mRNA_cap_C PF03919.10 EGG41075.1 - 0.12 12.6 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain CybS PF05328.7 EGG41077.1 - 0.13 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 CybS DDE_Tnp_IS240 PF13610.1 EGG41079.1 - 1.4e-22 80.1 0.9 2.7e-22 79.2 0.6 1.5 1 0 0 1 1 1 1 DDE domain rve PF00665.21 EGG41079.1 - 6.1e-08 32.7 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS66 PF03050.9 EGG41079.1 - 9.6e-06 25.0 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family rve_3 PF13683.1 EGG41079.1 - 1.8e-05 24.1 0.1 5.7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain SWIM PF04434.12 EGG41079.1 - 0.00042 19.7 0.1 0.00083 18.7 0.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-LYAR PF08790.6 EGG41079.1 - 0.011 15.4 1.0 0.026 14.2 0.7 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Zn_Tnp_IS1 PF03811.8 EGG41079.1 - 0.014 14.8 2.3 0.014 14.8 1.6 1.8 2 0 0 2 2 2 0 InsA N-terminal domain MULE PF10551.4 EGG41079.1 - 0.024 14.8 0.0 0.069 13.3 0.0 1.8 1 0 0 1 1 1 0 MULE transposase domain HTH_23 PF13384.1 EGG41079.1 - 0.13 11.9 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain zf-ISL3 PF14690.1 EGG41079.1 - 4.8 7.2 8.0 0.88 9.6 0.6 3.0 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RHH_1 PF01402.16 EGG41080.1 - 0.0099 15.7 0.4 0.015 15.1 0.3 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family YicC_N PF03755.8 EGG41081.1 - 0.032 14.1 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 YicC-like family, N-terminal region LOH1CR12 PF10158.4 EGG41082.1 - 0.044 13.5 0.2 0.22 11.3 0.1 1.9 1 1 1 2 2 2 0 Tumour suppressor protein zf-Mss51 PF13824.1 EGG41082.1 - 0.057 13.2 0.1 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF217 PF02697.9 EGG41082.1 - 0.49 10.6 3.9 4.7 7.5 1.6 2.6 2 1 0 2 2 2 0 Uncharacterized ACR, COG1753 MethyltransfD12 PF02086.10 EGG41083.1 - 5.4e-64 216.1 1.0 6.2e-64 215.9 0.7 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 EGG41083.1 - 0.0014 18.5 0.0 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF2089 PF09862.4 EGG41083.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) Cons_hypoth95 PF03602.10 EGG41083.1 - 0.011 15.1 0.1 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Archaeal_AmoA PF12942.2 EGG41084.1 - 5.8e-107 355.4 10.5 6.9e-107 355.1 7.3 1.0 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) Bax1-I PF01027.15 EGG41085.1 - 0.0067 16.0 4.3 0.0069 16.0 3.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 ETRAMP PF09716.5 EGG41085.1 - 0.81 9.6 2.9 1.7 8.6 0.1 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FixP_N PF14715.1 EGG41085.1 - 2 7.8 7.0 13 5.2 1.8 2.3 1 1 1 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP AmoC PF04896.7 EGG41086.1 - 2.4e-15 56.2 4.6 3e-15 55.9 3.2 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C Monooxygenase_B PF04744.7 EGG41087.1 - 1.5e-06 27.1 0.2 3.8e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Monooxygenase subunit B protein DUF1469 PF07332.6 EGG41092.1 - 0.018 14.7 2.5 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Ribosomal_S13_N PF08069.7 EGG41094.1 - 1.9e-26 91.6 0.1 3.4e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EGG41094.1 - 4.4e-17 61.6 0.4 7.8e-17 60.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Nnf1 PF03980.9 EGG41094.1 - 0.01 15.8 0.2 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Nnf1 HDA2-3 PF11496.3 EGG41094.1 - 0.085 11.6 0.4 0.62 8.8 0.2 1.9 1 1 1 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DHH PF01368.15 EGG41095.1 - 4e-09 36.2 0.2 6.7e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.14 EGG41095.1 - 2.1e-07 30.5 2.7 2.7e-07 30.1 0.3 2.5 3 0 0 3 3 3 1 DHHA1 domain Pcc1 PF09341.5 EGG41096.1 - 0.00061 19.7 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 Imm6 PF14434.1 EGG41096.1 - 0.054 13.1 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Immunity protein Imm6 Ribosomal_L12 PF00542.14 EGG41096.1 - 0.061 13.3 1.1 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain tRNA-synt_2b PF00587.20 EGG41097.1 - 7.5e-36 123.2 0.1 1.3e-35 122.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGG41097.1 - 4.4e-24 84.5 11.3 9.7e-24 83.4 7.9 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FimP PF09766.4 EGG41097.1 - 0.018 14.1 3.3 0.037 13.0 2.3 1.4 1 0 0 1 1 1 0 Fms-interacting protein TMPIT PF07851.8 EGG41097.1 - 0.19 10.7 3.7 0.39 9.7 2.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_S3Ae PF01015.13 EGG41098.1 - 1.3e-64 217.1 5.6 1.4e-64 216.9 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF4468 PF14730.1 EGG41098.1 - 0.056 13.1 0.2 0.18 11.5 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold Band_7 PF01145.20 EGG41098.1 - 0.091 12.6 0.5 0.49 10.2 0.3 2.1 1 1 0 1 1 1 0 SPFH domain / Band 7 family RNA_binding PF01877.12 EGG41099.1 - 1.5e-24 86.3 3.5 1.7e-24 86.0 2.5 1.1 1 0 0 1 1 1 1 RNA binding ORF6N PF10543.4 EGG41099.1 - 0.4 10.7 3.9 0.46 10.5 1.4 2.1 1 1 1 2 2 2 0 ORF6N domain FAD_binding_2 PF00890.19 EGG41101.1 - 1.3e-06 27.5 2.0 0.019 13.8 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EGG41101.1 - 2.4e-05 23.6 0.0 4.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EGG41101.1 - 8e-05 21.6 0.9 0.27 10.0 0.2 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGG41101.1 - 0.00022 19.9 0.0 0.0064 15.1 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.12 EGG41101.1 - 0.00023 20.3 1.4 0.0031 16.6 0.9 2.2 1 1 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EGG41101.1 - 0.00065 18.7 0.1 0.00089 18.2 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGG41101.1 - 0.0012 18.0 0.2 0.068 12.2 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGG41101.1 - 0.0015 18.4 0.9 0.01 15.7 0.6 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG41101.1 - 0.032 14.2 0.2 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGG41101.1 - 0.061 11.7 0.0 0.11 10.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein AAA_5 PF07728.9 EGG41102.1 - 1.2e-23 83.3 0.1 1.7e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGG41102.1 - 3.7e-13 49.2 0.0 5.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EGG41102.1 - 4.7e-08 33.2 0.0 7.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGG41102.1 - 8.4e-07 28.9 0.1 1.4e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGG41102.1 - 3.7e-06 26.5 0.0 6.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EGG41102.1 - 1.9e-05 24.4 0.1 2.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Archaeal ATPase RuvB_N PF05496.7 EGG41102.1 - 8.6e-05 21.6 0.1 0.0017 17.4 0.1 2.4 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus MCM PF00493.18 EGG41102.1 - 0.00022 20.1 0.0 0.00029 19.7 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_17 PF13207.1 EGG41102.1 - 0.00027 21.7 0.0 0.00062 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG41102.1 - 0.0003 20.8 0.0 0.00046 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGG41102.1 - 0.00055 20.0 0.0 0.0042 17.1 0.0 2.2 1 1 1 2 2 2 1 Sigma-54 interaction domain Miro PF08477.8 EGG41102.1 - 0.00092 19.6 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EGG41102.1 - 0.00094 19.3 0.1 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGG41102.1 - 0.0019 17.3 0.1 0.34 10.0 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EGG41102.1 - 0.0043 16.6 0.0 0.05 13.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbbQ_C PF08406.5 EGG41102.1 - 0.0054 16.7 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA_33 PF13671.1 EGG41102.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGG41102.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGG41102.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EGG41102.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_2 PF07724.9 EGG41102.1 - 0.014 15.3 0.5 0.039 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) KAP_NTPase PF07693.9 EGG41102.1 - 0.039 12.9 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain RNA12 PF10443.4 EGG41102.1 - 0.047 12.1 0.0 0.073 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_11 PF13086.1 EGG41102.1 - 0.047 13.2 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGG41102.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EGG41102.1 - 0.05 13.9 0.1 0.1 12.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 EGG41102.1 - 0.078 12.4 0.1 0.15 11.5 0.1 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 EGG41102.1 - 0.086 11.7 0.0 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SE PF00437.15 EGG41102.1 - 0.092 11.6 0.0 0.22 10.4 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EGG41102.1 - 0.095 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 EGG41102.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EGG41102.1 - 0.11 12.0 0.1 0.29 10.7 0.0 1.8 2 1 0 2 2 1 0 AAA domain Ras PF00071.17 EGG41102.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras family AAA_18 PF13238.1 EGG41102.1 - 0.18 12.0 1.1 0.28 11.4 0.8 1.6 1 1 0 1 1 1 0 AAA domain VWA PF00092.23 EGG41103.1 - 2.2e-09 37.2 0.1 1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGG41103.1 - 2.7e-08 34.1 0.1 3.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGG41103.1 - 0.01 15.6 0.0 0.049 13.4 0.0 2.1 2 1 0 2 2 2 0 vWA found in TerF C terminus Redoxin PF08534.5 EGG41105.1 - 1.3e-09 37.7 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGG41105.1 - 7.7e-08 32.0 0.1 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EGG41105.1 - 0.00025 21.1 0.2 0.00055 19.9 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.10 EGG41106.1 - 9.9e-45 152.7 22.1 1.2e-44 152.4 15.3 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 EGG41106.1 - 4.4e-08 33.1 16.5 6.7e-08 32.5 11.5 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2910 PF11139.3 EGG41106.1 - 0.0008 18.6 10.4 0.093 11.8 5.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2910) Baculo_11_kDa PF06143.6 EGG41106.1 - 0.46 9.8 0.0 0.46 9.8 0.0 2.7 4 0 0 4 4 4 0 Baculovirus 11 kDa family PALP PF00291.20 EGG41107.1 - 6.7e-21 74.8 0.0 5.8e-20 71.7 0.0 2.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ASCH PF04266.9 EGG41108.1 - 2.9e-10 40.4 0.0 3.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ASCH domain TBP PF00352.16 EGG41109.1 - 1.9e-61 203.4 0.1 6.1e-31 105.6 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGG41109.1 - 0.00012 22.0 0.0 0.096 12.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) NERD PF08378.6 EGG41111.1 - 0.0015 18.8 3.0 0.093 13.0 0.2 2.3 2 1 0 2 2 2 2 Nuclease-related domain I-set PF07679.11 EGG41112.1 - 0.011 15.5 0.2 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain A2M_N PF01835.14 EGG41112.1 - 0.026 14.7 0.1 0.066 13.4 0.0 1.7 1 0 0 1 1 1 0 MG2 domain Methylase_S PF01420.14 EGG41112.1 - 0.041 13.8 0.8 0.041 13.8 0.6 2.1 2 1 0 2 2 2 0 Type I restriction modification DNA specificity domain HTH_10 PF04967.7 EGG41113.1 - 0.033 13.7 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain Imm41 PF15583.1 EGG41113.1 - 0.059 13.1 0.1 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 41 HTH_Tnp_4 PF13613.1 EGG41113.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease P-II PF00543.17 EGG41114.1 - 1.6e-12 47.8 3.7 1.8e-12 47.6 2.5 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Erv26 PF04148.8 EGG41115.1 - 0.037 13.4 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 SH PF01445.12 EGG41115.1 - 0.045 13.3 0.3 0.088 12.4 0.2 1.5 1 0 0 1 1 1 0 Viral small hydrophobic protein Flavi_NS4A PF01350.12 EGG41115.1 - 0.068 12.7 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A SdpI PF13630.1 EGG41115.1 - 2.4 7.9 6.8 3.5 7.4 4.7 1.3 1 1 0 1 1 1 0 SdpI/YhfL protein family zf-C3HC4 PF00097.20 EGG41118.1 - 7.9 6.2 9.2 5 6.8 1.0 3.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) AsnC_trans_reg PF01037.16 EGG41119.1 - 1.7e-20 72.4 0.6 5.8e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 AsnC family GYD PF08734.6 EGG41119.1 - 0.0011 18.6 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 2 GYD domain ACT_4 PF13291.1 EGG41119.1 - 0.0035 17.6 1.4 22 5.4 0.0 3.9 3 1 1 4 4 4 0 ACT domain Herpes_BBRF1 PF04793.7 EGG41119.1 - 0.07 11.8 1.9 2.8 6.6 0.2 2.0 2 0 0 2 2 2 0 BRRF1-like protein NapD PF03927.8 EGG41119.1 - 0.074 12.8 0.5 0.7 9.7 0.0 2.5 2 1 0 2 2 2 0 NapD protein DUF1296 PF06972.6 EGG41119.1 - 0.13 12.2 1.3 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) SicP-binding PF09119.5 EGG41119.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 SicP binding AsnC_trans_reg PF01037.16 EGG41120.1 - 4e-13 48.8 0.1 4.7e-13 48.6 0.1 1.0 1 0 0 1 1 1 1 AsnC family Dus PF01207.12 EGG41121.1 - 3.2e-73 246.2 0.0 3.7e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EGG41121.1 - 4.2e-08 32.5 0.1 4.6e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.15 EGG41121.1 - 1.7e-06 27.2 0.0 3.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NanE PF04131.9 EGG41121.1 - 5.4e-05 22.2 0.0 0.00013 20.9 0.0 1.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EGG41121.1 - 0.0034 16.6 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein IMPDH PF00478.20 EGG41121.1 - 0.0051 15.7 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 EGG41121.1 - 0.055 12.7 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 PcrB family FMN_dh PF01070.13 EGG41121.1 - 0.07 11.9 0.1 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase VPS11_C PF12451.3 EGG41121.1 - 5.5 6.9 6.4 36 4.3 0.3 3.1 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal TSP_3 PF02412.13 EGG41122.1 - 7.3e-43 143.7 190.3 0.0011 18.4 0.5 23.6 23 7 1 24 24 24 17 Thrombospondin type 3 repeat NOPS PF08075.6 EGG41122.1 - 4.9e-06 26.8 37.1 27 5.2 0.0 14.1 15 0 0 15 15 15 1 NOPS (NUC059) domain DUF282 PF03380.9 EGG41122.1 - 3e-05 23.6 20.9 18 5.1 0.1 10.0 10 0 0 10 10 10 4 Caenorhabditis protein of unknown function, DUF282 ChitinaseA_N PF08329.5 EGG41122.1 - 0.35 10.6 4.4 8.9 6.0 0.1 3.1 3 0 0 3 3 3 0 Chitinase A, N-terminal domain TcdB_toxin_midN PF12256.3 EGG41122.1 - 2.2 7.7 20.2 3.5 7.0 0.1 6.0 5 1 1 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region TSP_3 PF02412.13 EGG41123.1 - 7.2e-48 159.7 221.6 4.9e-05 22.7 1.7 23.9 25 7 0 25 25 25 17 Thrombospondin type 3 repeat DUF282 PF03380.9 EGG41123.1 - 2.7e-05 23.7 32.7 20 5.0 0.1 12.9 13 0 0 13 13 13 4 Caenorhabditis protein of unknown function, DUF282 ChitinaseA_N PF08329.5 EGG41123.1 - 0.025 14.3 1.3 5.1 6.8 0.1 2.9 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Excalibur PF05901.6 EGG41123.1 - 1.2 9.5 0.0 1.2 9.5 0.0 17.4 18 2 0 18 18 18 0 Excalibur calcium-binding domain DUF2709 PF10915.3 EGG41123.1 - 6 5.7 7.8 6.6 5.6 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2709) TSP_3 PF02412.13 EGG41124.1 - 4.4e-56 186.0 227.0 1.2e-05 24.6 1.0 26.3 22 11 4 26 26 26 20 Thrombospondin type 3 repeat DUF282 PF03380.9 EGG41124.1 - 3.1e-09 36.4 26.7 1.4 8.7 0.1 12.2 13 0 0 13 13 13 4 Caenorhabditis protein of unknown function, DUF282 NOPS PF08075.6 EGG41124.1 - 0.037 14.4 52.2 6.8 7.1 0.1 15.8 16 5 2 18 18 18 0 NOPS (NUC059) domain Wyosine_form PF08608.7 EGG41125.1 - 1.2e-19 70.0 0.0 2.3e-18 66.0 0.0 2.6 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.16 EGG41125.1 - 1.4e-19 70.8 0.0 5.5e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EGG41125.1 - 0.0031 17.5 0.1 0.019 14.9 0.1 2.2 1 1 0 1 1 1 1 4Fe-4S single cluster domain SAS4 PF15460.1 EGG41125.1 - 0.0036 17.1 1.0 0.0068 16.2 0.3 1.9 1 1 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 AAT PF03417.11 EGG41125.1 - 0.033 13.6 0.1 0.066 12.6 0.0 1.5 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Peptidase_M26_N PF05342.9 EGG41125.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region Fer4_12 PF13353.1 EGG41125.1 - 0.072 13.2 0.4 0.33 11.0 0.3 2.1 1 1 0 1 1 1 0 4Fe-4S single cluster domain Ham1p_like PF01725.11 EGG41126.1 - 1.5e-46 158.1 0.1 1.7e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RIO1 PF01163.17 EGG41127.1 - 4.6e-10 39.1 0.1 6.2e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 EGG41127.1 - 4.7e-09 35.7 0.3 6.3e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGG41127.1 - 1.8e-08 33.6 0.1 9.2e-08 31.4 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG41127.1 - 9.7e-06 25.4 0.0 0.07 12.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGG41127.1 - 0.00077 18.6 0.5 0.0025 16.9 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase WaaY PF06176.6 EGG41127.1 - 0.008 15.4 1.7 0.013 14.7 1.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1679 PF07914.6 EGG41127.1 - 0.0081 14.8 0.0 0.0089 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EGG41127.1 - 0.074 12.6 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EGG41127.1 - 0.16 11.0 0.3 0.35 9.9 0.3 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase Cation_efflux PF01545.16 EGG41128.1 - 2.2e-46 158.2 7.1 2.5e-46 158.0 4.9 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1212 PF06738.7 EGG41128.1 - 7.1 6.0 8.6 8.9 5.7 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1212) GRAM PF02893.15 EGG41129.1 - 0.0023 17.4 0.1 0.0074 15.7 0.0 2.0 2 1 0 2 2 2 1 GRAM domain bPH_3 PF14470.1 EGG41129.1 - 0.056 13.6 0.3 0.13 12.5 0.2 1.7 1 1 0 1 1 1 0 Bacterial PH domain Peptidase_M22 PF00814.20 EGG41130.1 - 4.8e-75 252.5 0.0 5.7e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 EGG41130.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase MMR_HSR1_C PF08438.5 EGG41131.1 - 5.7e-31 106.9 0.7 1.3e-30 105.8 0.1 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EGG41131.1 - 8.8e-18 64.3 0.1 1.1e-16 60.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EGG41131.1 - 4.6e-12 45.5 0.1 1.2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EGG41131.1 - 1.6e-06 27.5 0.2 6.2e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.8 EGG41131.1 - 0.031 14.0 1.1 0.083 12.6 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF933) AAA_18 PF13238.1 EGG41132.1 - 2.8e-14 53.5 0.4 2.8e-14 53.5 0.3 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGG41132.1 - 7.6e-11 42.8 0.2 9.5e-11 42.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGG41132.1 - 0.00068 19.8 0.0 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 EGG41132.1 - 0.0024 17.7 0.1 0.024 14.5 0.0 2.0 1 1 1 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.10 EGG41132.1 - 0.0025 17.5 0.6 0.0082 15.8 0.0 2.1 2 1 0 2 2 2 1 NTPase KTI12 PF08433.5 EGG41132.1 - 0.0053 15.9 0.1 0.0092 15.2 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Sulfotransfer_1 PF00685.22 EGG41132.1 - 0.031 13.5 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain CoaE PF01121.15 EGG41132.1 - 0.04 13.3 0.1 0.08 12.3 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase SKI PF01202.17 EGG41132.1 - 0.044 13.6 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 Shikimate kinase DUF258 PF03193.11 EGG41132.1 - 0.057 12.6 0.2 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGG41132.1 - 0.065 13.2 0.0 0.073 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EGG41132.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGG41132.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain TGT PF01702.13 EGG41133.1 - 5.3e-49 166.6 0.0 7.4e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fer4 PF00037.22 EGG41134.1 - 1.7e-11 43.1 10.3 6.6e-06 25.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EGG41134.1 - 2.1e-10 40.0 7.5 3.6e-05 23.4 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGG41134.1 - 1.2e-09 38.4 3.8 1.7e-09 37.8 2.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGG41134.1 - 5.7e-09 35.6 3.2 9.5e-09 34.9 2.3 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGG41134.1 - 8e-09 34.9 9.0 0.00011 21.9 1.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EGG41134.1 - 4.2e-08 32.9 1.4 6.2e-08 32.3 1.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGG41134.1 - 2.4e-06 27.8 4.9 0.008 16.5 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGG41134.1 - 3.1e-06 27.6 8.7 0.00094 19.7 6.2 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_4 PF12800.2 EGG41134.1 - 1.7e-05 24.7 9.7 0.038 14.3 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EGG41134.1 - 3.2e-05 24.0 6.9 0.00015 21.9 5.0 1.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGG41134.1 - 8.1e-05 23.2 1.5 0.3 11.8 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EGG41134.1 - 0.00015 21.6 5.0 0.00042 20.2 3.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 EGG41134.1 - 0.0002 21.6 11.3 0.044 14.3 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGG41134.1 - 0.0023 18.2 6.4 0.05 13.9 4.4 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGG41134.1 - 0.0037 17.6 6.8 0.19 12.1 1.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain DUF3000 PF11452.3 EGG41135.1 - 0.14 11.4 0.3 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Beta-Casp PF10996.3 EGG41136.1 - 2.7e-19 69.3 0.0 7.7e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EGG41136.1 - 4.1e-16 59.2 0.2 1.2e-15 57.7 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGG41136.1 - 1.4e-13 50.8 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EGG41136.1 - 2.3e-12 46.5 0.1 1.1e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EGG41136.1 - 3.4e-05 23.5 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain OGG_N PF07934.7 EGG41137.1 - 2.7e-14 53.1 0.4 4.1e-13 49.3 0.2 2.4 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EGG41137.1 - 1.2e-11 44.8 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RNA_helicase PF00910.17 EGG41137.1 - 0.013 15.6 0.2 0.041 14.0 0.1 1.8 1 0 0 1 1 1 0 RNA helicase DUF4330 PF14221.1 EGG41137.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DoxA PF07680.6 EGG41138.1 - 0.0072 15.9 0.1 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 TQO small subunit DoxA Copper-bind PF00127.15 EGG41139.1 - 5e-06 26.6 0.0 7.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EGG41139.1 - 0.033 14.0 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupredoxin-like domain Cytochrom_B_N_2 PF13631.1 EGG41140.1 - 1.9e-24 86.3 7.1 1.9e-24 86.3 4.9 3.9 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 EGG41140.1 - 2.1e-08 34.2 1.7 2.1e-08 34.2 1.2 3.2 4 0 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.1 EGG41140.1 - 0.0018 18.3 3.1 0.0018 18.3 2.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4405) Rieske PF00355.21 EGG41141.1 - 7.2e-09 35.1 0.1 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_Fe-S_N PF10399.4 EGG41141.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 EGG41141.1 - 0.0018 18.1 0.9 0.0018 18.1 0.6 1.9 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Peptidase_S8 PF00082.17 EGG41142.1 - 1.6e-29 102.9 8.8 1e-28 100.3 6.1 2.3 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EGG41142.1 - 4.2e-05 23.9 0.2 0.0011 19.3 0.0 2.7 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) EF-hand_1 PF00036.27 EGG41142.1 - 5.8 6.4 8.3 12 5.4 0.0 3.7 4 0 0 4 4 4 0 EF hand Baculo_PEP_C PF04513.7 EGG41143.1 - 0.013 15.3 1.5 0.029 14.1 1.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EGG41143.1 - 0.025 13.7 2.7 0.04 13.0 1.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EGG41143.1 - 0.047 12.6 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Filamin PF00630.14 EGG41143.1 - 0.089 13.3 0.1 0.28 11.7 0.0 2.0 1 1 0 1 1 1 0 Filamin/ABP280 repeat NPV_P10 PF05531.7 EGG41143.1 - 0.32 11.2 2.1 22 5.3 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ThiF PF00899.16 EGG41145.1 - 4.8e-44 149.4 0.9 1.2e-43 148.2 0.6 1.6 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EGG41145.1 - 2.3e-17 62.3 0.1 4.3e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain ThiS PF02597.15 EGG41145.1 - 2.4e-07 31.0 0.1 8.1e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 ThiS family Shikimate_DH PF01488.15 EGG41145.1 - 0.0026 17.8 0.1 0.0082 16.2 0.1 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EGG41145.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGG41145.1 - 0.1 13.0 0.4 1.7 9.1 0.2 2.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.20 EGG41146.1 - 3e-66 223.7 1.0 3.5e-66 223.5 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.5 EGG41146.1 - 0.076 13.0 0.2 0.41 10.7 0.0 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF1510 PF07423.6 EGG41147.1 - 0.0029 16.9 2.7 0.0042 16.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4446 PF14584.1 EGG41147.1 - 0.073 12.9 0.4 0.1 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4097 PF13349.1 EGG41147.1 - 0.33 10.4 4.4 0.98 8.9 2.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) PRA-CH PF01502.13 EGG41148.1 - 1.3e-35 120.8 0.1 1.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase His_biosynth PF00977.16 EGG41149.1 - 4.6e-84 281.2 1.5 5.2e-84 281.0 1.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 EGG41149.1 - 1.1e-07 31.0 0.0 0.00011 21.1 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) PcrB PF01884.12 EGG41149.1 - 3.1e-05 23.3 1.4 0.00011 21.5 0.1 2.2 2 1 0 2 2 2 1 PcrB family TMP-TENI PF02581.12 EGG41149.1 - 5.1e-05 22.4 0.1 0.019 14.0 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI NMO PF03060.10 EGG41149.1 - 0.00014 21.1 0.4 0.03 13.4 0.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase DHO_dh PF01180.16 EGG41149.1 - 0.00014 20.8 0.1 0.023 13.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase ThiG PF05690.9 EGG41149.1 - 0.00039 19.5 0.1 0.54 9.2 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EGG41149.1 - 0.0087 14.9 1.6 0.1 11.4 0.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 EGG41149.1 - 0.014 13.9 0.0 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain His_biosynth PF00977.16 EGG41150.1 - 8.9e-71 237.7 0.9 1e-70 237.6 0.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein IGPS PF00218.16 EGG41150.1 - 4.9e-05 22.5 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase NMO PF03060.10 EGG41150.1 - 0.0044 16.2 0.0 0.34 9.9 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase PcrB PF01884.12 EGG41150.1 - 0.0058 15.9 0.1 0.053 12.7 0.0 2.0 2 0 0 2 2 2 1 PcrB family TMP-TENI PF02581.12 EGG41150.1 - 0.032 13.3 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Trp_syntA PF00290.15 EGG41150.1 - 0.064 11.7 0.0 0.31 9.5 0.0 2.0 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Syd PF07348.7 EGG41150.1 - 0.092 12.0 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Syd protein (SUKH-2) GATase PF00117.23 EGG41151.1 - 2.1e-35 121.9 0.0 2.4e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG41151.1 - 4.1e-07 29.6 0.0 4.5e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 EGG41151.1 - 0.00018 21.1 0.0 0.0019 17.8 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGG41151.1 - 0.00019 21.0 0.0 0.00035 20.1 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain IGPD PF00475.13 EGG41152.1 - 7.8e-50 168.5 0.8 1.1e-49 168.0 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF916 PF06030.7 EGG41152.1 - 0.019 14.7 0.2 0.18 11.6 0.0 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF916) ANF_receptor PF01094.23 EGG41152.1 - 0.09 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region HAD_2 PF13419.1 EGG41153.1 - 2.1e-05 24.8 0.2 0.016 15.4 0.0 2.6 2 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG41153.1 - 0.0012 19.2 0.2 0.048 14.0 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGG41153.1 - 0.0036 16.9 0.0 0.0092 15.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGG41153.1 - 0.1 12.7 0.9 0.25 11.4 0.6 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.16 EGG41154.1 - 5.1e-42 144.1 0.0 6.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGG41154.1 - 0.1 11.2 0.0 0.62 8.7 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V Histidinol_dh PF00815.15 EGG41156.1 - 1.6e-132 442.0 0.2 1.9e-132 441.7 0.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Tubulin_C PF03953.12 EGG41156.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Tubulin C-terminal domain HisG PF01634.13 EGG41157.1 - 1.1e-37 129.1 0.0 1.4e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EGG41157.1 - 7.8e-14 51.3 0.0 1.8e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain HMG-CoA_red PF00368.13 EGG41159.1 - 2.3e-84 283.2 4.9 3e-84 282.8 3.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase GSDH PF07995.6 EGG41160.1 - 3.1e-79 266.4 0.0 4.1e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EGG41160.1 - 0.0027 17.5 0.0 1.9 8.6 0.0 3.9 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.6 EGG41160.1 - 0.011 15.6 0.2 3.2 8.0 0.0 4.1 4 0 0 4 4 4 0 Two component regulator propeller DUF1743 PF08489.6 EGG41162.1 - 1.1e-33 115.5 0.0 2.6e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1743) Exo5 PF09810.4 EGG41162.1 - 0.043 13.0 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease Zn_Tnp_IS1595 PF12760.2 EGG41162.1 - 0.23 11.2 1.6 0.4 10.5 1.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain C1_1 PF00130.17 EGG41162.1 - 0.4 10.4 3.0 0.7 9.6 2.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 EGG41162.1 - 2.3 8.0 9.9 1.5 8.6 1.4 2.8 1 1 1 2 2 2 0 BED zinc finger Diphthamide_syn PF01866.12 EGG41163.1 - 8.3e-81 271.5 0.0 9.9e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_11 PF13414.1 EGG41164.1 - 4.5e-22 77.4 4.4 1.9e-11 43.4 0.1 3.3 1 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGG41164.1 - 2.5e-20 71.1 7.5 2e-08 33.4 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG41164.1 - 3.1e-17 61.0 1.2 8e-05 22.2 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGG41164.1 - 5.5e-14 52.3 0.0 8.6e-07 29.4 0.0 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG41164.1 - 2.5e-12 46.9 0.0 0.00013 22.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG41164.1 - 2.4e-11 43.3 1.2 6.9e-05 22.7 0.2 3.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGG41164.1 - 2.7e-10 39.2 5.1 0.00015 21.2 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG41164.1 - 5.6e-10 39.0 0.1 0.41 11.2 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EGG41164.1 - 2.7e-08 33.8 1.3 0.0016 18.5 0.0 2.5 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EGG41164.1 - 9.3e-08 31.8 0.3 0.099 12.5 0.0 4.1 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EGG41164.1 - 3.7e-07 29.9 0.0 5e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG41164.1 - 9.9e-07 28.1 0.1 0.035 13.8 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG41164.1 - 1e-06 28.8 0.0 0.07 13.7 0.0 4.3 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG41164.1 - 6.9e-06 25.8 2.8 0.023 14.8 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 EGG41164.1 - 0.00024 20.7 2.4 0.088 12.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 EGG41164.1 - 0.003 17.4 0.4 3.9 7.6 0.0 4.0 4 0 0 4 4 4 1 PPR repeat SSXT PF05030.7 EGG41164.1 - 0.0031 17.0 0.3 1.8 8.1 0.0 2.8 2 1 0 2 2 2 1 SSXT protein (N-terminal region) TPR_10 PF13374.1 EGG41164.1 - 0.0032 17.3 0.0 2.4 8.2 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Sec16_C PF12931.2 EGG41164.1 - 0.075 12.7 0.1 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 B1 PF02246.10 EGG41164.1 - 0.079 12.8 0.1 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein L b1 domain DUF1106 PF06523.6 EGG41164.1 - 2.1 8.2 5.6 16 5.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1106) ADH_zinc_N PF00107.21 EGG41165.1 - 6.6e-31 106.5 0.0 2.2e-30 104.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGG41165.1 - 3.9e-24 84.5 0.2 6.4e-24 83.8 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGG41165.1 - 1.8e-17 64.3 0.0 3.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 EGG41165.1 - 0.017 15.1 0.5 0.051 13.5 0.0 2.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ECR1_N PF14382.1 EGG41166.1 - 1.5e-05 24.1 0.0 0.00012 21.3 0.0 2.3 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EGG41166.1 - 0.0022 17.8 0.6 0.14 12.0 0.2 2.6 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 Prok-RING_1 PF14446.1 EGG41166.1 - 0.0086 15.7 1.9 0.0086 15.7 1.3 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PDT PF00800.13 EGG41167.1 - 6.4e-59 198.5 0.1 8.2e-59 198.2 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EGG41167.1 - 7.1e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain Thioredoxin_6 PF13848.1 EGG41167.1 - 0.011 15.5 0.3 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain B2-adapt-app_C PF09066.5 EGG41167.1 - 0.011 15.5 0.3 0.023 14.5 0.2 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain PetM PF08041.6 EGG41168.1 - 0.21 11.1 0.2 0.21 11.1 0.2 1.9 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 TrbC PF04956.8 EGG41168.1 - 4.2 7.4 6.1 8.8 6.4 0.2 2.6 3 0 0 3 3 3 0 TrbC/VIRB2 family IMPDH PF00478.20 EGG41169.1 - 1.2e-134 448.6 7.8 1.4e-134 448.4 5.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGG41169.1 - 2.9e-24 84.5 1.1 1.3e-11 44.0 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EGG41169.1 - 1.3e-08 34.3 12.0 0.0003 20.0 4.8 2.4 1 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EGG41169.1 - 1.5e-06 27.3 6.4 4.7e-06 25.6 4.4 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EGG41169.1 - 7.1e-06 25.4 1.6 0.035 13.3 0.1 2.7 1 1 1 2 2 2 2 Histidine biosynthesis protein PK PF00224.16 EGG41169.1 - 0.00056 18.6 0.3 0.012 14.2 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain DHO_dh PF01180.16 EGG41169.1 - 0.00064 18.7 5.8 0.00089 18.2 0.9 2.4 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.9 EGG41169.1 - 0.00098 18.1 1.1 0.00098 18.1 0.7 2.1 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 EGG41169.1 - 0.019 14.0 2.9 0.024 13.6 0.5 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.1 EGG41169.1 - 0.032 13.4 1.2 0.05 12.8 0.1 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase B12-binding PF02310.14 EGG41169.1 - 0.033 14.0 0.2 0.073 12.9 0.2 1.5 1 0 0 1 1 1 0 B12 binding domain Aldolase PF01081.14 EGG41169.1 - 0.043 12.9 0.9 0.11 11.6 0.7 1.8 1 0 0 1 1 1 0 KDPG and KHG aldolase PcrB PF01884.12 EGG41169.1 - 0.15 11.2 9.0 2.7 7.1 0.2 4.4 3 2 1 4 4 4 0 PcrB family Pterin_bind PF00809.17 EGG41170.1 - 2.4e-39 134.8 0.6 6.6e-39 133.4 0.4 1.7 1 1 0 1 1 1 1 Pterin binding enzyme LuxS PF02664.10 EGG41170.1 - 0.062 12.8 0.2 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) MAF_flag10 PF01973.13 EGG41171.1 - 5.2e-40 136.7 0.6 7.5e-40 136.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPK_catalytic PF04263.11 EGG41171.1 - 0.024 14.1 0.4 2.1 7.9 0.1 2.3 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain Shikimate_DH PF01488.15 EGG41171.1 - 0.051 13.6 0.1 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GATase PF00117.23 EGG41173.1 - 1.1e-42 145.6 0.0 1.7e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EGG41173.1 - 1.1e-31 108.3 0.0 2.6e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EGG41173.1 - 2e-12 46.5 0.2 4.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EGG41173.1 - 2.3e-08 33.7 0.0 9.1e-08 31.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 EGG41173.1 - 8.2e-06 25.4 0.0 0.0008 18.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EGG41173.1 - 0.00012 20.7 0.0 0.0033 16.0 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 EGG41173.1 - 0.0062 16.0 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.8 EGG41173.1 - 0.008 15.4 0.0 0.37 10.0 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC bact-PGI_C PF10432.4 EGG41174.1 - 1.4e-35 122.2 0.0 3.2e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal region SIS PF01380.17 EGG41174.1 - 1.5e-08 34.3 0.2 2.7e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 SIS domain PGI PF00342.14 EGG41174.1 - 0.054 11.9 0.3 0.099 11.0 0.2 1.4 1 0 0 1 1 1 0 Phosphoglucose isomerase SIS_2 PF13580.1 EGG41174.1 - 0.37 10.5 1.9 0.67 9.6 0.2 2.3 2 1 0 2 2 2 0 SIS domain CTP_transf_3 PF02348.14 EGG41175.1 - 4.7e-18 65.6 0.3 6.8e-18 65.0 0.2 1.4 1 1 0 1 1 1 1 Cytidylyltransferase Arg_repressor PF01316.16 EGG41175.1 - 0.038 13.5 0.1 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain LAGLIDADG_1 PF00961.14 EGG41176.1 - 0.12 12.9 6.7 0.098 13.2 2.6 2.2 2 0 0 2 2 2 0 LAGLIDADG endonuclease DUF2835 PF11197.3 EGG41177.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Radical_SAM PF04055.16 EGG41178.1 - 1e-16 61.5 0.0 4.8e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.14 EGG41178.1 - 2.6e-12 46.6 0.0 4.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain Flavodoxin_3 PF12641.2 EGG41178.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain NADH-G_4Fe-4S_3 PF10588.4 EGG41178.1 - 0.2 10.9 0.1 0.2 10.9 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region MAF_flag10 PF01973.13 EGG41179.1 - 3.4e-16 59.2 0.1 5.3e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF115 Epimerase PF01370.16 EGG41180.1 - 2.1e-39 135.4 0.0 2.2e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG41180.1 - 3.2e-29 101.4 0.4 3.8e-29 101.2 0.3 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG41180.1 - 1.4e-20 73.3 0.0 1.7e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGG41180.1 - 2.9e-20 72.2 0.9 2.7e-18 65.7 0.6 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGG41180.1 - 3.2e-16 59.8 0.0 3.8e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGG41180.1 - 5.9e-16 58.2 0.7 1.6e-15 56.8 0.5 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EGG41180.1 - 2.5e-07 30.0 0.0 2.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EGG41180.1 - 3.8e-07 29.6 0.4 7.3e-07 28.6 0.3 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EGG41180.1 - 1.6e-06 28.1 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 EGG41180.1 - 3e-05 23.9 0.2 7.1e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EGG41180.1 - 0.00041 20.0 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 EGG41180.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.5 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.11 EGG41180.1 - 0.036 14.4 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGG41180.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase bPH_3 PF14470.1 EGG41180.1 - 0.42 10.9 3.0 1.7 8.9 2.1 1.9 1 1 0 1 1 1 0 Bacterial PH domain Epimerase_Csub PF13950.1 EGG41181.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EGG41181.1 - 0.0017 17.3 0.0 0.0019 17.1 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SPASM PF13186.1 EGG41182.1 - 5.5e-13 49.0 1.2 2.1e-10 40.7 0.2 3.6 2 1 0 2 2 2 1 Iron-sulfur cluster-binding domain Radical_SAM PF04055.16 EGG41182.1 - 2.9e-11 43.7 0.1 8.2e-11 42.3 0.0 1.8 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EGG41182.1 - 0.00066 19.8 0.1 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGG41182.1 - 0.0017 18.3 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Ubiquitin_3 PF14836.1 EGG41182.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Cupin_2 PF07883.6 EGG41183.1 - 0.02 14.3 0.2 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 Cupin domain Cupin_7 PF12973.2 EGG41183.1 - 0.028 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 ChrR Cupin-like domain GDPD_2 PF13653.1 EGG41184.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.12 EGG41184.1 - 0.021 14.3 0.0 0.19 11.2 0.0 1.9 1 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family DUF718 PF05336.8 EGG41184.1 - 0.1 12.4 1.8 0.28 11.0 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF718) AAA_14 PF13173.1 EGG41184.1 - 0.16 11.8 1.1 0.2 11.5 0.8 1.4 1 0 0 1 1 1 0 AAA domain NTP_transf_3 PF12804.2 EGG41185.1 - 3.4e-05 23.9 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGG41185.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CRC_subunit PF08624.5 EGG41185.1 - 0.08 12.8 0.1 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit PGM_PMM_III PF02880.11 EGG41186.1 - 2.8e-09 37.0 0.0 4.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGG41186.1 - 1.8e-08 34.6 0.0 3.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 EGG41186.1 - 8.5e-07 28.5 0.5 1.6e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EGG41186.1 - 0.0013 18.6 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.11 EGG41187.1 - 1.2e-09 37.7 0.0 3e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I IL1_propep PF02394.11 EGG41187.1 - 0.054 13.8 0.7 0.13 12.6 0.3 1.7 1 1 1 2 2 2 0 Interleukin-1 propeptide UPF0278 PF08745.6 EGG41187.1 - 0.1 11.8 0.7 0.17 11.1 0.5 1.6 1 1 0 1 1 1 0 UPF0278 family Sulfatase PF00884.18 EGG41188.1 - 6.5e-28 97.7 0.0 1.3e-27 96.8 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGG41188.1 - 1.8e-08 34.0 0.4 0.0043 16.4 0.2 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGG41188.1 - 9.8e-05 21.8 0.0 0.0004 19.8 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase_C PF14707.1 EGG41188.1 - 0.13 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase WavE PF07507.6 EGG41189.1 - 7.6e-16 57.8 2.7 3.6e-14 52.3 1.9 2.2 1 1 0 1 1 1 1 WavE lipopolysaccharide synthesis CMAS PF02353.15 EGG41190.1 - 0.00091 18.3 1.9 0.0013 17.8 1.3 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Kri1 PF05178.7 EGG41190.1 - 0.091 13.0 2.0 0.28 11.4 1.4 2.0 1 1 0 1 1 1 0 KRI1-like family Methyltransf_31 PF13847.1 EGG41190.1 - 0.18 11.4 12.2 0.037 13.6 3.9 2.3 1 1 1 2 2 2 0 Methyltransferase domain TFIIF_alpha PF05793.7 EGG41190.1 - 0.28 9.4 8.8 0.11 10.8 3.6 2.0 2 1 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Radical_SAM PF04055.16 EGG41191.1 - 2.9e-14 53.5 0.1 7.6e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.14 EGG41191.1 - 2.9e-06 27.1 0.0 2.3e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain Y_phosphatase2 PF03162.8 EGG41191.1 - 0.018 14.4 0.1 0.044 13.1 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family PCI_Csn8 PF10075.4 EGG41191.1 - 0.019 14.7 0.0 9.6 5.9 0.0 2.9 1 1 1 2 2 2 0 COP9 signalosome, subunit CSN8 Fer4_12 PF13353.1 EGG41191.1 - 0.087 12.9 0.8 0.35 10.9 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain NTP_transferase PF00483.18 EGG41192.1 - 3.9e-10 39.4 0.0 4.2e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGG41192.1 - 9.1e-10 38.8 0.0 9.6e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGG41192.1 - 0.00023 20.7 0.0 0.00025 20.6 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NUDIX PF00293.23 EGG41194.1 - 1.1e-15 57.4 0.0 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Methyltransf_24 PF13578.1 EGG41195.1 - 6.7e-09 36.5 0.0 1.5e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TylF PF05711.6 EGG41195.1 - 3e-06 26.5 0.0 2.3e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) AAA_14 PF13173.1 EGG41195.1 - 0.025 14.4 0.3 0.059 13.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain NTP_transf_3 PF12804.2 EGG41196.1 - 6.8e-07 29.5 0.0 9.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGG41196.1 - 0.054 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ank PF00023.25 EGG41196.1 - 0.055 13.3 0.5 1.7 8.5 0.0 3.1 3 1 0 3 3 3 0 Ankyrin repeat TPP_enzyme_C PF02775.16 EGG41197.1 - 2.5e-16 59.6 0.0 6.9e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1392 PF07154.6 EGG41197.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1392) TPP_enzyme_N PF02776.13 EGG41198.1 - 4.8e-06 26.1 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transket_pyr PF02779.19 EGG41198.1 - 0.008 15.6 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain PEP_mutase PF13714.1 EGG41199.1 - 1.2e-66 224.3 0.1 1.4e-66 224.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EGG41199.1 - 7.5e-09 34.3 0.0 2.1e-08 32.8 0.0 1.6 1 1 1 2 2 2 1 Isocitrate lyase family Fe-ADH PF00465.14 EGG41200.1 - 2.2e-50 171.3 0.0 2.9e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGG41200.1 - 3e-21 75.8 0.0 4.7e-21 75.2 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EGG41200.1 - 8.7e-06 24.8 0.1 0.061 12.2 0.0 2.1 2 0 0 2 2 2 2 3-dehydroquinate synthase Polysacc_synt_3 PF13440.1 EGG41201.1 - 2.3e-09 37.1 26.9 2.3e-09 37.1 18.7 3.0 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.12 EGG41201.1 - 1.5e-08 34.2 32.5 1.5e-08 34.2 22.5 3.3 3 1 1 4 4 4 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGG41202.1 - 1.4e-26 93.3 0.0 1.9e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG41202.1 - 1.3e-18 67.6 0.0 1.5e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG41202.1 - 3.7e-10 39.7 0.0 5.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG41202.1 - 7.1e-09 35.4 0.1 1.1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG41202.1 - 0.00012 20.8 0.4 0.00016 20.4 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG41202.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF713 PF05218.9 EGG41202.1 - 0.14 11.8 0.7 0.25 11.0 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF713) NAD_binding_10 PF13460.1 EGG41202.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding CTP_transf_3 PF02348.14 EGG41203.1 - 4.4e-33 114.7 1.4 5.3e-33 114.4 1.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DUF3877 PF12993.2 EGG41203.1 - 0.0015 18.1 3.9 0.073 12.6 0.3 2.3 2 1 0 2 2 2 2 Domain of unknown function, E. rectale Gene description (DUF3877) NTP_transf_3 PF12804.2 EGG41203.1 - 0.0026 17.8 0.0 0.0066 16.5 0.0 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain Agenet PF05641.7 EGG41203.1 - 0.031 14.4 0.4 0.13 12.4 0.3 2.2 1 1 0 1 1 1 0 Agenet domain DUF3969 PF13108.1 EGG41203.1 - 0.16 11.6 4.0 0.89 9.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) DegT_DnrJ_EryC1 PF01041.12 EGG41204.1 - 5.9e-96 321.6 0.0 6.6e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EGG41204.1 - 4.7e-11 42.3 0.0 6.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGG41204.1 - 1.5e-10 40.5 0.1 2.3e-10 39.9 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 EGG41204.1 - 6.6e-09 34.7 0.3 7.8e-09 34.4 0.2 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Cys_Met_Meta_PP PF01053.15 EGG41204.1 - 1.3e-05 23.6 0.0 2.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGG41204.1 - 0.00075 18.3 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF2172 PF09940.4 EGG41205.1 - 6.1e-159 528.5 1.9 6.5e-141 469.1 0.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF2172) DUF4423 PF14394.1 EGG41205.1 - 0.00019 21.0 0.0 0.00041 19.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) RepL PF05732.6 EGG41205.1 - 0.0034 16.6 0.5 0.0075 15.4 0.4 1.6 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) Peptidase_M28 PF04389.12 EGG41205.1 - 0.0035 17.1 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 HTH_24 PF13412.1 EGG41205.1 - 0.017 14.5 2.7 0.093 12.1 0.4 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Antibiotic_NAT PF02522.9 EGG41206.1 - 1.5e-48 165.0 0.0 1.8e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase Tox-ART-HYE1 PF15634.1 EGG41206.1 - 0.0051 15.8 0.8 0.0076 15.2 0.5 1.2 1 0 0 1 1 1 1 HYE1 signature containing ADP-ribosyltransferase ELK PF03789.8 EGG41206.1 - 0.096 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 ELK domain TylF PF05711.6 EGG41207.1 - 2.3e-08 33.4 0.0 3.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 EGG41207.1 - 0.00042 21.1 0.0 0.00091 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EGG41207.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_24 PF13578.1 EGG41208.1 - 2.3e-09 38.0 0.0 4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41208.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Metallophos_2 PF12850.2 EGG41208.1 - 0.0018 18.1 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CmcI PF04989.7 EGG41208.1 - 0.0078 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase PCMT PF01135.14 EGG41208.1 - 0.0094 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_17 PF12692.2 EGG41208.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Cons_hypoth95 PF03602.10 EGG41208.1 - 0.046 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Nup35_RRM PF05172.8 EGG41208.1 - 0.066 12.9 0.4 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Lactamase_B_3 PF13483.1 EGG41209.1 - 5.5e-16 58.7 0.0 1.9e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EGG41209.1 - 2.2e-11 43.6 0.2 4.4e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NeuB PF03102.9 EGG41210.1 - 9.3e-38 129.7 0.6 2.2e-37 128.5 0.4 1.6 1 1 0 1 1 1 1 NeuB family Acetyltransf_3 PF13302.1 EGG41211.1 - 1.7e-10 41.2 0.0 2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGG41211.1 - 0.0029 17.7 0.1 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain His_binding PF02098.11 EGG41211.1 - 0.033 14.0 0.1 0.058 13.2 0.1 1.5 1 1 0 1 1 1 0 Tick histamine binding protein Polysacc_synt_2 PF02719.10 EGG41212.1 - 2.2e-98 328.8 0.1 2.6e-98 328.5 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGG41212.1 - 2.2e-29 102.5 0.0 3.7e-28 98.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG41212.1 - 3.7e-24 84.8 0.2 1.5e-21 76.3 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG41212.1 - 1.8e-18 66.4 0.0 1.3e-16 60.3 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGG41212.1 - 8.9e-12 45.3 0.0 1.3e-11 44.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGG41212.1 - 2.7e-11 42.8 0.4 2.5e-09 36.4 0.2 2.7 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 EGG41212.1 - 4.5e-09 36.4 0.0 6.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGG41212.1 - 8.9e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EGG41212.1 - 9.4e-06 25.3 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EGG41212.1 - 0.0001 22.6 0.0 0.00029 21.1 0.0 1.9 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGG41212.1 - 0.00026 21.0 0.3 0.0054 16.8 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EGG41212.1 - 0.0028 17.6 0.1 0.011 15.7 0.1 2.1 2 1 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 EGG41212.1 - 0.0066 15.4 0.0 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EGG41212.1 - 0.0081 16.4 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase_2 PF02350.14 EGG41213.1 - 2.1e-07 30.0 1.0 2.9e-07 29.6 0.7 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyphos_transf PF04464.9 EGG41213.1 - 1.5e-05 23.9 5.0 3.1e-05 22.8 0.7 2.2 2 0 0 2 2 2 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Capsule_synth PF05159.9 EGG41213.1 - 0.015 14.8 2.1 0.058 12.8 1.4 2.0 1 1 0 1 1 1 0 Capsule polysaccharide biosynthesis protein Amidase_3 PF01520.13 EGG41213.1 - 0.016 14.9 0.3 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase SAS4 PF15460.1 EGG41213.1 - 0.088 12.6 1.1 0.28 11.0 0.2 2.3 3 1 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 HCaRG PF07258.9 EGG41214.1 - 0.077 12.5 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 HCaRG protein Methyltransf_14 PF08484.6 EGG41215.1 - 9.3e-52 174.8 0.0 1.5e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.6 EGG41215.1 - 1.7e-17 62.6 0.2 3.3e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.1 EGG41215.1 - 6.2e-17 61.7 0.0 1.3e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41215.1 - 4.8e-06 26.9 0.1 9.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG41215.1 - 0.00077 19.8 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41215.1 - 0.0012 19.3 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG41215.1 - 0.0015 18.1 0.1 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2540 PF10802.3 EGG41215.1 - 0.032 13.9 0.8 0.075 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Glycos_transf_2 PF00535.21 EGG41216.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGG41216.1 - 2.6e-12 47.0 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGG41216.1 - 4.7e-06 26.4 0.0 6.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.4 EGG41216.1 - 0.033 13.2 0.3 0.23 10.5 0.2 2.1 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGG41217.1 - 9.7e-13 48.1 1.4 1e-12 48.0 0.9 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGG41217.1 - 0.0002 21.2 0.0 0.00021 21.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Methyltransf_31 PF13847.1 EGG41218.1 - 9.4e-23 80.4 4.3 1.9e-22 79.4 0.5 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41218.1 - 8.5e-14 51.8 0.1 1.9e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41218.1 - 2.2e-13 50.7 0.0 4.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG41218.1 - 2.7e-12 47.0 0.0 6.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41218.1 - 5.7e-12 45.6 0.1 1.4e-11 44.3 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG41218.1 - 1.1e-11 44.9 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG41218.1 - 6.9e-07 28.7 0.1 1.1e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EGG41218.1 - 2.3e-06 26.5 0.0 3.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EGG41218.1 - 3.4e-06 26.2 0.7 1.1e-05 24.5 0.1 1.8 1 1 1 2 2 2 1 Putative methyltransferase CheR PF01739.13 EGG41218.1 - 2e-05 23.9 0.1 0.00015 21.1 0.1 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 EGG41218.1 - 2.2e-05 24.4 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGG41218.1 - 0.0003 19.7 0.1 0.00084 18.2 0.1 1.6 2 0 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.13 EGG41218.1 - 0.0032 16.6 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGG41218.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGG41218.1 - 0.04 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Rsm22 PF09243.5 EGG41218.1 - 0.078 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RmlD_sub_bind PF04321.12 EGG41219.1 - 2.7e-64 216.8 0.0 3.9e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGG41219.1 - 1e-25 90.5 0.2 1.5e-25 90.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGG41219.1 - 6.4e-12 44.9 0.0 1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGG41219.1 - 6.6e-11 41.6 2.2 3.8e-10 39.1 1.5 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGG41219.1 - 1.8e-08 33.4 1.8 4.4e-08 32.1 1.2 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGG41219.1 - 5.5e-05 23.2 0.0 6.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EGG41219.1 - 0.068 13.0 0.1 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ACPS PF01648.15 EGG41220.1 - 3.8e-15 55.7 0.1 5.5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 3-dmu-9_3-mt PF06983.8 EGG41220.1 - 0.12 12.7 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase AMP-binding PF00501.23 EGG41221.1 - 3.4e-76 256.3 0.0 4.1e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG41221.1 - 2.6e-09 37.9 0.0 5.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.19 EGG41222.1 - 5.4e-13 47.8 16.9 5.3e-07 28.8 6.2 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGG41222.1 - 1.1e-09 37.6 13.5 0.0015 18.0 0.0 3.7 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NAD_synthase PF02540.12 EGG41223.1 - 8.1e-55 185.3 0.5 7.1e-28 97.1 0.0 2.0 1 1 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 EGG41223.1 - 8.4e-05 21.2 0.0 0.00015 20.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EGG41223.1 - 0.00032 20.2 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGG41223.1 - 0.0011 18.2 0.0 0.0055 16.0 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC UPF0240 PF06784.6 EGG41223.1 - 0.0061 16.2 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) MerR-DNA-bind PF09278.6 EGG41224.1 - 0.049 14.0 0.1 4.3 7.8 0.0 2.1 1 1 1 2 2 2 0 MerR, DNA binding NAD_synthase PF02540.12 EGG41224.1 - 0.051 12.4 0.3 0.059 12.2 0.2 1.0 1 0 0 1 1 1 0 NAD synthase DUF2316 PF10078.4 EGG41224.1 - 0.092 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF387 PF04079.11 EGG41224.1 - 0.099 12.0 0.1 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Epimerase PF01370.16 EGG41225.1 - 9.3e-60 201.9 0.0 1.1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGG41225.1 - 5.9e-19 68.0 0.0 8.1e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGG41225.1 - 1.9e-16 59.7 0.0 7.9e-14 51.1 0.0 2.7 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.14 EGG41225.1 - 6e-16 57.9 0.0 7.3e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGG41225.1 - 2.8e-14 52.6 0.0 3e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2527 PF10736.4 EGG41225.1 - 0.039 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) dTDP_sugar_isom PF00908.12 EGG41226.1 - 1.3e-15 57.1 0.1 1.7e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Cupin_2 PF07883.6 EGG41226.1 - 0.021 14.3 0.0 0.048 13.1 0.0 1.7 1 1 0 1 1 1 0 Cupin domain FdtA PF05523.6 EGG41226.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal Hydrolase_3 PF08282.7 EGG41227.1 - 2e-15 57.0 1.3 7e-15 55.2 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG41227.1 - 5.2e-09 36.8 0.1 2.8e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG41227.1 - 0.00091 19.4 1.5 0.0072 16.5 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGG41227.1 - 0.0043 16.9 0.1 0.08 12.8 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG41227.1 - 0.008 16.4 0.1 0.59 10.3 0.0 2.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HTH_26 PF13443.1 EGG41227.1 - 0.034 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DUF1699 PF08004.6 EGG41227.1 - 0.064 12.7 0.4 1.9 8.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) NeuB PF03102.9 EGG41228.1 - 2e-70 236.6 0.6 2.4e-70 236.4 0.4 1.0 1 0 0 1 1 1 1 NeuB family SIS_2 PF13580.1 EGG41229.1 - 3.5e-28 98.0 1.2 5e-28 97.5 0.8 1.2 1 0 0 1 1 1 1 SIS domain SIS PF01380.17 EGG41229.1 - 5.9e-06 25.9 0.1 2.8e-05 23.7 0.0 1.9 1 1 1 2 2 2 1 SIS domain TylF PF05711.6 EGG41230.1 - 3.3e-08 32.9 0.1 2.6e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 EGG41230.1 - 4e-06 27.6 0.0 7.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AP_endonuc_2 PF01261.19 EGG41232.1 - 2.5e-14 53.0 0.0 3.2e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4434 PF14488.1 EGG41232.1 - 0.004 16.8 0.2 0.71 9.5 0.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4434) adh_short_C2 PF13561.1 EGG41233.1 - 2.5e-18 66.7 0.0 3.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG41233.1 - 2.2e-08 34.1 0.1 8.4e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 EGG41233.1 - 5.1e-06 25.5 0.0 9.3e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGG41233.1 - 0.00053 19.5 0.0 0.0012 18.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 EGG41234.1 - 4.1e-23 82.1 0.0 6.1e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGG41234.1 - 0.0062 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4295 PF14128.1 EGG41234.1 - 0.019 14.5 0.1 0.1 12.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) Semialdhyde_dh PF01118.19 EGG41234.1 - 0.025 14.8 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGG41234.1 - 0.068 13.6 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EGG41235.1 - 9.4e-20 71.1 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG41235.1 - 7.7e-14 52.0 0.1 1.3e-13 51.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG41235.1 - 3e-05 23.7 0.0 5.8e-05 22.8 0.0 1.5 1 1 1 2 2 2 1 KR domain DUF900 PF05990.7 EGG41235.1 - 0.0025 17.1 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Epimerase PF01370.16 EGG41235.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cmc1 PF08583.5 EGG41235.1 - 0.056 13.2 0.5 0.1 12.3 0.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Med28 PF11594.3 EGG41235.1 - 0.23 11.7 5.2 0.56 10.4 0.3 2.3 1 1 1 2 2 2 0 Mediator complex subunit 28 Methyltransf_31 PF13847.1 EGG41236.1 - 8.5e-24 83.8 0.0 1.4e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41236.1 - 5.1e-23 81.5 0.0 7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41236.1 - 1.8e-18 67.1 0.0 3.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG41236.1 - 3.2e-17 62.8 0.0 7e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41236.1 - 4.1e-16 59.2 0.0 9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGG41236.1 - 2.4e-11 42.9 0.0 3.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EGG41236.1 - 1.3e-10 40.8 0.0 2.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGG41236.1 - 1.4e-09 38.1 0.0 4.8e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EGG41236.1 - 4.5e-09 35.7 0.0 7.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGG41236.1 - 6.7e-09 35.7 0.0 1.6e-08 34.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EGG41236.1 - 2.9e-08 33.1 0.0 4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EGG41236.1 - 7e-07 28.5 0.0 9.9e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 EGG41236.1 - 1.8e-06 27.4 0.0 7.5e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 EGG41236.1 - 1e-05 24.9 0.8 0.026 13.8 0.1 2.4 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain DREV PF05219.7 EGG41236.1 - 3e-05 23.0 0.0 6.5e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase FtsJ PF01728.14 EGG41236.1 - 4.9e-05 23.4 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.6 EGG41236.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EGG41236.1 - 0.00031 20.4 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EGG41236.1 - 0.00041 19.8 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) N6_N4_Mtase PF01555.13 EGG41236.1 - 0.00092 18.7 0.3 0.0018 17.8 0.1 1.6 2 0 0 2 2 2 1 DNA methylase Methyltransf_4 PF02390.12 EGG41236.1 - 0.0018 17.3 0.0 0.005 15.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EGG41236.1 - 0.007 15.9 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EGG41236.1 - 0.0088 15.6 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein AdoMet_MTase PF07757.8 EGG41236.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.7 EGG41236.1 - 0.027 13.4 0.1 0.097 11.6 0.0 1.7 1 1 1 2 2 2 0 N2227-like protein Methyltransf_2 PF00891.13 EGG41236.1 - 0.089 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_3 PF01596.12 EGG41236.1 - 0.1 11.6 0.2 0.19 10.7 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase PMT_2 PF13231.1 EGG41237.1 - 7.3e-10 38.9 17.7 7.3e-10 38.9 12.3 3.4 3 1 1 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 EGG41237.1 - 0.00034 20.0 14.8 0.00034 20.0 10.3 2.8 2 2 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase AIF-MLS PF14962.1 EGG41237.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MerC PF03203.9 EGG41237.1 - 1.2 9.4 6.4 0.13 12.6 0.8 2.1 2 0 0 2 2 2 0 MerC mercury resistance protein RE_NgoBV PF09564.5 EGG41238.1 - 0.045 12.9 0.1 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 NgoBV restriction endonuclease DUF4010 PF13194.1 EGG41239.1 - 0.019 14.2 0.1 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Neur_chan_memb PF02932.11 EGG41239.1 - 0.019 14.8 0.6 0.023 14.5 0.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LCD1 PF09798.4 EGG41240.1 - 0.023 12.6 0.4 0.024 12.6 0.3 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2254 PF10011.4 EGG41240.1 - 0.024 13.1 0.2 0.028 12.9 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) NTP_transferase PF00483.18 EGG41241.1 - 1.6e-55 188.1 0.0 2e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGG41241.1 - 8.9e-09 35.6 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EGG41241.1 - 2.7e-08 32.9 18.5 1.3e-05 24.4 1.7 4.2 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGG41241.1 - 7.6e-05 22.1 1.4 7.6e-05 22.1 1.0 3.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Pentapeptide_3 PF13576.1 EGG41241.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DUF1244 PF06844.6 EGG41241.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) DUF3473 PF11959.3 EGG41242.1 - 3.6e-30 104.1 0.0 5.1e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) Polysacc_deac_1 PF01522.16 EGG41242.1 - 7.3e-14 51.4 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Capsule_synth PF05159.9 EGG41243.1 - 7.7e-16 58.3 1.0 1.5e-15 57.4 0.6 1.5 1 1 0 1 1 1 1 Capsule polysaccharide biosynthesis protein ATP-synt_ab_C PF00306.22 EGG41243.1 - 2.4 8.6 5.3 4 7.9 0.8 3.2 2 1 1 3 3 3 0 ATP synthase alpha/beta chain, C terminal domain Glyco_trans_1_4 PF13692.1 EGG41244.1 - 7.3e-16 58.5 0.0 1.1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGG41244.1 - 1.2e-06 28.6 0.0 4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGG41244.1 - 0.0011 18.4 0.0 0.0029 17.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Epimerase PF01370.16 EGG41245.1 - 7.8e-53 179.3 0.0 1.1e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGG41245.1 - 1.3e-07 30.8 0.0 1.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 EGG41245.1 - 0.00037 20.3 0.0 0.0008 19.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGG41245.1 - 0.014 14.0 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGG41245.1 - 0.018 14.2 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EGG41245.1 - 0.027 13.3 0.0 0.056 12.3 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein BHD_2 PF10404.4 EGG41245.1 - 0.034 14.4 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Epimerase PF01370.16 EGG41246.1 - 2.8e-51 174.2 0.1 3.6e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGG41246.1 - 1.3e-26 93.1 0.0 1.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGG41246.1 - 5.5e-19 67.9 0.3 1e-18 67.0 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGG41246.1 - 1.5e-18 66.6 0.1 3e-13 49.2 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EGG41246.1 - 2e-16 59.7 1.6 7.8e-15 54.5 1.1 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGG41246.1 - 8.1e-08 32.4 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding AdoMet_MTase PF07757.8 EGG41246.1 - 0.0028 17.7 0.0 1.2 9.2 0.0 2.7 2 1 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase adh_short PF00106.20 EGG41246.1 - 0.0071 16.2 0.0 2.1 8.2 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase NmrA PF05368.8 EGG41246.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase_Csub PF13950.1 EGG41246.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EGG41247.1 - 1.2e-91 306.6 1.6 1.6e-91 306.2 1.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGG41247.1 - 5.9e-22 78.2 0.2 1.5e-20 73.6 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG41247.1 - 8.9e-20 70.5 1.6 1.2e-19 70.1 1.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG41247.1 - 1.6e-16 60.0 0.1 5.5e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGG41247.1 - 9e-09 34.6 1.3 2.1e-07 30.1 0.8 2.5 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EGG41247.1 - 4e-08 33.4 0.2 8.5e-08 32.4 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGG41247.1 - 2.7e-06 26.8 2.5 7.2e-06 25.4 1.7 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EGG41247.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 EGG41247.1 - 0.014 15.7 0.2 0.39 11.1 0.0 2.9 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EGG41247.1 - 0.02 13.9 0.1 0.043 12.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EGG41247.1 - 0.032 14.2 1.1 0.21 11.6 0.7 2.2 1 1 1 2 2 2 0 TrkA-N domain KR PF08659.5 EGG41247.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 EGG41248.1 - 1.7e-42 145.5 0.0 2.7e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG41248.1 - 4.3e-21 74.8 0.2 5.1e-19 68.0 0.1 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGG41248.1 - 5.5e-21 74.6 0.0 4.8e-18 64.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EGG41248.1 - 3.9e-19 68.6 0.1 4.8e-16 58.4 0.0 2.6 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGG41248.1 - 1.4e-17 63.5 0.0 1.7e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGG41248.1 - 2.3e-09 37.5 0.0 4e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGG41248.1 - 0.0014 18.5 0.0 0.33 10.8 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase DapB_N PF01113.15 EGG41248.1 - 0.17 11.8 0.6 0.5 10.2 0.0 2.1 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Glycos_transf_1 PF00534.15 EGG41249.1 - 2.3e-35 121.5 0.1 3.9e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGG41249.1 - 9e-18 64.7 0.0 2.3e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGG41249.1 - 1.1e-12 48.0 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGG41249.1 - 8.2e-12 45.1 0.1 2.1e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGG41249.1 - 3e-07 30.7 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EGG41249.1 - 9.6e-07 28.7 1.8 6.2e-06 26.0 1.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.6 EGG41249.1 - 9e-05 22.0 0.0 0.00067 19.2 0.0 1.9 1 1 1 2 2 2 1 Starch synthase catalytic domain PS_pyruv_trans PF04230.8 EGG41249.1 - 0.012 15.3 0.5 0.044 13.5 0.3 1.9 1 1 0 1 1 1 0 Polysaccharide pyruvyl transferase DUF2608 PF11019.3 EGG41249.1 - 0.036 13.0 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Radical_SAM PF04055.16 EGG41250.1 - 5.3e-15 55.9 0.2 5.3e-15 55.9 0.1 2.7 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.1 EGG41250.1 - 1.1e-07 31.8 0.0 1.1e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EGG41250.1 - 1.3e-07 31.8 0.0 4.6e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain TrmB PF01978.14 EGG41251.1 - 4.6e-21 74.2 0.1 1.7e-20 72.4 0.0 2.0 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 EGG41251.1 - 2.3e-07 30.0 0.0 2.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.5 EGG41251.1 - 6.6e-05 22.4 0.0 0.00031 20.2 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.17 EGG41251.1 - 0.00024 20.7 0.0 0.001 18.7 0.0 2.0 1 1 1 2 2 2 1 MarR family HTH_24 PF13412.1 EGG41251.1 - 0.0023 17.2 0.0 0.0057 16.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 EGG41251.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 Winged helix DNA-binding domain Penicillinase_R PF03965.11 EGG41251.1 - 0.0052 16.8 0.0 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 Penicillinase repressor Rrf2 PF02082.15 EGG41251.1 - 0.047 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator YflT PF11181.3 EGG41251.1 - 0.056 13.6 0.2 2.9 8.0 0.0 2.9 2 1 0 3 3 3 0 Heat induced stress protein YflT PLDc_2 PF13091.1 EGG41251.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 PLD-like domain MarR_2 PF12802.2 EGG41251.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_9 PF08221.6 EGG41251.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Fe_dep_repr_C PF02742.10 EGG41252.1 - 6.1e-20 70.6 0.1 6.1e-20 70.6 0.1 1.6 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.14 EGG41252.1 - 2.7e-15 56.0 0.2 4.2e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.17 EGG41252.1 - 2.9e-05 23.6 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 EGG41252.1 - 6e-05 23.2 0.0 9.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.15 EGG41252.1 - 6.2e-05 23.0 0.1 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.2 EGG41252.1 - 0.00013 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 EGG41252.1 - 0.00082 19.0 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.1 EGG41252.1 - 0.00083 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_45 PF14947.1 EGG41252.1 - 0.0011 18.7 0.2 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_5 PF01022.15 EGG41252.1 - 0.0027 17.3 0.1 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_1 PF00126.22 EGG41252.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family TFIIE_beta PF02186.10 EGG41252.1 - 0.021 14.8 0.3 0.044 13.7 0.2 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain DUF2250 PF10007.4 EGG41252.1 - 0.047 13.6 0.2 0.076 12.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) IF2_N PF04760.10 EGG41252.1 - 0.055 13.1 0.8 0.14 11.8 0.1 2.0 2 1 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region ANT PF03374.9 EGG41252.1 - 0.06 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Penicillinase_R PF03965.11 EGG41252.1 - 0.066 13.3 0.5 0.087 12.9 0.3 1.4 1 1 0 1 1 1 0 Penicillinase repressor HTH_11 PF08279.7 EGG41252.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain NLPC_P60 PF00877.14 EGG41252.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 NlpC/P60 family HTH_6 PF01418.12 EGG41252.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family DUF2387 PF09526.5 EGG41253.1 - 0.0014 18.4 0.5 0.0016 18.3 0.3 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) SWIM PF04434.12 EGG41253.1 - 0.36 10.3 2.3 0.53 9.8 1.6 1.4 1 0 0 1 1 1 0 SWIM zinc finger UPF0047 PF01894.12 EGG41254.1 - 2.3e-37 127.4 0.0 2.9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 eRF1_1 PF03463.10 EGG41257.1 - 1.1e-19 70.2 0.3 2.4e-19 69.2 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EGG41257.1 - 1.3e-12 48.2 0.2 3.8e-12 46.6 0.1 1.8 1 1 1 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 EGG41257.1 - 2.8e-10 40.4 0.7 4.2e-09 36.6 0.2 2.6 2 0 0 2 2 2 1 eRF1 domain 3 Ribosomal_L7Ae PF01248.21 EGG41257.1 - 0.0024 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TNV_CP PF03898.8 EGG41257.1 - 0.072 12.1 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Satellite tobacco necrosis virus coat protein CutA1 PF03091.10 EGG41258.1 - 7.3e-30 102.6 4.9 8e-30 102.5 3.4 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein TFIIE_beta PF02186.10 EGG41258.1 - 0.016 15.1 1.6 0.028 14.3 0.2 2.0 1 1 1 2 2 2 0 TFIIE beta subunit core domain Glycos_transf_2 PF00535.21 EGG41258.1 - 0.019 14.6 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF240 PF03086.9 EGG41258.1 - 0.046 13.3 0.3 0.068 12.8 0.2 1.3 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 Peptidase_M50 PF02163.17 EGG41259.1 - 2.9e-25 88.3 0.1 1.6e-24 85.9 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M50 PDZ_2 PF13180.1 EGG41259.1 - 2.5e-09 36.9 0.0 4.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EGG41259.1 - 0.00051 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) ATP_bind_3 PF01171.15 EGG41260.1 - 4.2e-21 75.2 0.0 6.3e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 EGG41260.1 - 2.3e-05 23.1 0.0 3.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.14 EGG41260.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 EGG41260.1 - 0.04 14.2 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) DUF4145 PF13643.1 EGG41260.1 - 0.095 12.5 0.5 0.36 10.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) C1_1 PF00130.17 EGG41260.1 - 5.5 6.7 16.4 0.33 10.7 2.5 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acylphosphatase PF00708.13 EGG41264.1 - 5.3e-28 96.9 0.4 5.8e-28 96.8 0.3 1.0 1 0 0 1 1 1 1 Acylphosphatase Ribosomal_L2_C PF03947.13 EGG41265.1 - 5.2e-33 113.6 2.1 7.9e-33 113.0 1.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGG41265.1 - 2.9e-09 36.7 0.0 1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain AAA PF00004.24 EGG41266.1 - 2.9e-100 331.6 0.0 5.8e-50 168.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGG41266.1 - 5.7e-29 99.9 0.2 2.5e-28 97.8 0.1 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EGG41266.1 - 1.7e-15 57.3 0.0 4.6e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGG41266.1 - 6.4e-15 55.6 0.2 2.3e-06 27.7 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 EGG41266.1 - 3.6e-14 52.3 0.0 8.7e-09 34.7 0.0 2.6 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGG41266.1 - 3.9e-13 49.6 0.1 5.9e-05 23.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGG41266.1 - 3.1e-11 42.6 0.8 0.00013 20.7 0.0 3.0 3 0 0 3 3 3 2 TIP49 C-terminus AAA_17 PF13207.1 EGG41266.1 - 6.7e-11 43.0 0.0 0.0001 23.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGG41266.1 - 8.2e-11 41.7 0.9 0.00038 20.2 0.2 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGG41266.1 - 1.1e-10 41.5 0.0 0.00035 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGG41266.1 - 5.5e-10 39.2 0.0 0.00016 21.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EGG41266.1 - 9.6e-10 37.8 0.4 3.8e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.12 EGG41266.1 - 6.5e-09 35.4 0.3 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EGG41266.1 - 6.6e-09 35.8 0.0 0.001 18.8 0.0 3.6 2 2 1 3 3 3 2 Archaeal ATPase Sigma54_activat PF00158.21 EGG41266.1 - 7.9e-08 31.9 0.2 0.032 13.7 0.0 3.4 3 1 0 3 3 3 2 Sigma-54 interaction domain CDC48_2 PF02933.12 EGG41266.1 - 1.3e-07 31.1 0.1 3.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 EGG41266.1 - 1.7e-07 30.8 3.8 0.0051 16.5 0.1 3.5 3 0 0 3 3 3 2 Part of AAA domain AAA_28 PF13521.1 EGG41266.1 - 9e-07 28.9 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGG41266.1 - 1.1e-06 28.7 0.0 0.028 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EGG41266.1 - 1.4e-06 28.6 0.1 0.031 14.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain KaiC PF06745.8 EGG41266.1 - 2.2e-06 26.9 1.4 0.1 11.6 0.0 3.8 3 1 1 4 4 3 2 KaiC Sigma54_activ_2 PF14532.1 EGG41266.1 - 3.8e-06 26.9 0.0 0.056 13.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EGG41266.1 - 4.2e-06 26.5 0.2 0.44 10.1 0.1 3.8 3 1 1 4 4 4 2 NACHT domain PhoH PF02562.11 EGG41266.1 - 4.5e-06 26.0 0.3 0.068 12.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Mg_chelatase PF01078.16 EGG41266.1 - 5.1e-06 25.7 0.7 0.032 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 EGG41266.1 - 8.3e-06 25.6 0.0 0.015 14.9 0.0 2.7 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_25 PF13481.1 EGG41266.1 - 1.3e-05 24.6 7.3 0.58 9.5 0.2 4.4 2 2 1 4 4 4 1 AAA domain NB-ARC PF00931.17 EGG41266.1 - 2.9e-05 23.0 0.0 0.057 12.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 EGG41266.1 - 3.8e-05 24.0 0.0 0.34 11.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.1 EGG41266.1 - 4.8e-05 23.0 0.2 0.031 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EGG41266.1 - 0.00011 21.2 0.0 0.056 12.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EGG41266.1 - 0.00035 20.1 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EGG41266.1 - 0.00043 20.0 1.3 2.4 7.8 0.0 4.1 3 1 1 4 4 3 1 NTPase DUF2075 PF09848.4 EGG41266.1 - 0.00059 18.9 0.0 0.29 10.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGG41266.1 - 0.00081 19.0 0.1 1 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 EGG41266.1 - 0.001 18.0 0.0 0.24 10.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EGG41266.1 - 0.0012 18.4 0.0 0.87 9.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EGG41266.1 - 0.0013 18.3 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EGG41266.1 - 0.0022 17.8 0.0 0.94 9.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 EGG41266.1 - 0.0026 17.3 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 EGG41266.1 - 0.0044 16.8 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase T2SE PF00437.15 EGG41266.1 - 0.0052 15.7 0.0 2.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein CPT PF07931.7 EGG41266.1 - 0.0075 15.9 0.0 0.87 9.1 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.16 EGG41266.1 - 0.011 15.2 0.1 7.7 5.9 0.0 3.4 2 1 1 3 3 3 0 Guanylate kinase AAA_10 PF12846.2 EGG41266.1 - 0.013 14.9 0.3 2.3 7.5 0.0 3.1 2 2 1 3 3 3 0 AAA-like domain AFG1_ATPase PF03969.11 EGG41266.1 - 0.014 14.2 0.0 2.3 6.9 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase AAA_29 PF13555.1 EGG41266.1 - 0.016 14.7 0.2 3 7.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EGG41266.1 - 0.05 13.0 0.0 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 EGG41266.1 - 0.064 12.7 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 EGG41266.1 - 0.077 11.9 0.0 9.2 5.0 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase KAP_NTPase PF07693.9 EGG41266.1 - 0.12 11.3 0.0 6.7 5.6 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain DUF258 PF03193.11 EGG41266.1 - 0.13 11.4 0.0 7.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Torsin PF06309.6 EGG41266.1 - 0.16 11.8 0.1 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Torsin IPT PF01745.11 EGG41266.1 - 0.19 10.8 0.2 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Asparaginase PF00710.15 EGG41267.1 - 6.7e-80 268.2 0.0 8.1e-80 268.0 0.0 1.0 1 0 0 1 1 1 1 Asparaginase DUF695 PF05117.7 EGG41267.1 - 0.037 13.9 0.1 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF695) Yippee-Mis18 PF03226.9 EGG41268.1 - 0.056 13.5 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF844 PF05815.6 EGG41268.1 - 0.14 10.9 0.2 0.15 10.8 0.1 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) NT5C PF06941.7 EGG41269.1 - 1.2e-10 41.2 1.6 1.6e-10 40.8 1.1 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) CTDII PF01556.13 EGG41270.1 - 1.8e-27 95.0 7.1 3.1e-22 78.2 0.4 3.2 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EGG41270.1 - 2e-26 91.5 0.7 3.2e-26 90.8 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGG41270.1 - 3e-14 52.7 19.9 5.5e-14 51.9 13.8 1.4 1 0 0 1 1 1 1 DnaJ central domain dCMP_cyt_deam_1 PF00383.17 EGG41270.1 - 1.8 8.2 4.9 1.4 8.5 0.8 2.1 1 1 1 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region HSP70 PF00012.15 EGG41271.1 - 5.5e-218 724.7 17.7 1.8e-197 656.9 9.3 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EGG41271.1 - 3.7e-17 61.9 6.6 3.7e-17 61.9 4.6 2.1 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGG41271.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1664 PF07889.7 EGG41271.1 - 3.1 7.6 8.6 0.49 10.2 0.9 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) GrpE PF01025.14 EGG41272.1 - 2.3e-38 131.3 5.1 2.8e-38 131.0 3.6 1.1 1 0 0 1 1 1 1 GrpE RPA_interact_M PF14767.1 EGG41272.1 - 0.029 15.0 0.9 0.72 10.6 0.6 2.5 1 1 1 2 2 2 0 Replication protein A interacting middle P4Ha_N PF08336.6 EGG41272.1 - 0.058 13.2 2.3 0.091 12.5 1.6 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3452 PF11934.3 EGG41272.1 - 0.084 12.1 1.0 0.14 11.4 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DUF1635 PF07795.6 EGG41272.1 - 0.14 11.4 4.4 0.22 10.8 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) UPF0172 PF03665.8 EGG41272.1 - 0.29 10.5 4.5 0.45 9.9 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF334 PF03904.8 EGG41272.1 - 0.34 10.1 10.2 0.51 9.6 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF354 PF04007.7 EGG41274.1 - 9.2e-55 185.8 7.8 1e-54 185.6 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) LpxB PF02684.10 EGG41274.1 - 0.00088 18.0 0.3 0.0018 16.9 0.2 1.5 1 1 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.14 EGG41274.1 - 0.0085 14.8 0.8 0.014 14.2 0.6 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase AAA_12 PF13087.1 EGG41274.1 - 0.041 13.2 0.8 0.082 12.2 0.5 1.5 1 0 0 1 1 1 0 AAA domain PFEMP PF03011.10 EGG41274.1 - 0.046 14.0 2.1 0.048 14.0 0.3 1.8 1 1 0 2 2 2 0 PFEMP DBL domain DUF2392 PF10288.4 EGG41274.1 - 0.055 13.8 0.7 0.19 12.1 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Glyco_tran_28_C PF04101.11 EGG41274.1 - 0.13 11.8 2.2 2 8.0 1.5 2.3 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UDPG_MGDP_dh_N PF03721.9 EGG41275.1 - 5.9e-07 29.0 0.7 0.006 15.9 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EGG41275.1 - 4.7e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain OKR_DC_1 PF01276.15 EGG41275.1 - 0.018 13.5 0.0 0.024 13.1 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain NAD_binding_2 PF03446.10 EGG41275.1 - 0.024 14.4 0.0 0.18 11.6 0.0 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase dTMP_synthase PF02593.9 EGG41275.1 - 0.059 12.7 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate synthase XdhC_C PF13478.1 EGG41275.1 - 0.095 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain ABC2_membrane PF01061.19 EGG41276.1 - 2.8e-20 72.3 22.1 2.8e-20 72.3 15.3 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EGG41276.1 - 2.1e-15 56.6 37.1 3e-15 56.1 18.2 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 EGG41276.1 - 5.7e-10 38.7 31.8 7.6e-10 38.3 22.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.1 EGG41276.1 - 0.34 10.1 33.8 4.4 6.5 23.4 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.22 EGG41277.1 - 3.9e-29 101.6 0.0 6.7e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGG41277.1 - 1.2e-12 48.4 4.4 1.5e-10 41.5 0.5 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGG41277.1 - 5.7e-07 28.9 6.2 8.1e-06 25.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF4162 PF13732.1 EGG41277.1 - 0.00046 20.6 1.5 0.0012 19.2 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_29 PF13555.1 EGG41277.1 - 0.0012 18.3 0.4 0.0022 17.4 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGG41277.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.16 EGG41277.1 - 0.033 13.3 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EGG41277.1 - 0.053 13.4 0.0 0.083 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EGG41277.1 - 0.084 13.1 10.1 0.79 10.0 7.0 2.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGG41277.1 - 0.091 11.9 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGG41277.1 - 0.12 12.3 3.2 3.8 7.4 0.3 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 EGG41277.1 - 0.12 11.6 2.1 9.4 5.3 0.1 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGG41277.1 - 0.16 12.7 1.1 1.1 10.0 0.7 2.4 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGG41277.1 - 1.6 8.4 6.9 6.3 6.5 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 tRNA_anti-codon PF01336.20 EGG41278.1 - 4.8e-12 45.5 1.0 0.0022 17.7 0.0 3.9 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain DEAD_assoc PF08494.6 EGG41279.1 - 0.0017 18.1 0.0 0.0053 16.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/H associated HypA PF01155.14 EGG41279.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family NMD3 PF04981.8 EGG41279.1 - 0.046 12.8 0.4 0.067 12.2 0.3 1.3 1 0 0 1 1 1 0 NMD3 family DEAD PF00270.24 EGG41280.1 - 7e-35 120.0 0.4 2e-34 118.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_assoc PF08494.6 EGG41280.1 - 4.9e-19 68.7 0.0 1.2e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/H associated Helicase_C PF00271.26 EGG41280.1 - 3.4e-16 58.8 0.1 5.2e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG41280.1 - 1.3e-09 38.1 0.1 3.5e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGG41280.1 - 5.7e-06 25.3 0.1 1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Secretin_N_2 PF07655.8 EGG41280.1 - 0.36 11.2 3.7 0.78 10.1 2.6 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain VPEP PF07589.6 EGG41281.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PEP-CTERM motif TIM21 PF08294.6 EGG41281.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.0 1 0 0 1 1 1 0 TIM21 Rad51 PF08423.6 EGG41282.1 - 1.6e-27 96.0 0.3 1.8e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EGG41282.1 - 5.5e-10 38.8 0.1 6.8e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EGG41282.1 - 9.5e-10 38.1 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGG41282.1 - 1.8e-07 30.5 7.7 8.6e-07 28.2 3.8 2.3 1 1 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 EGG41282.1 - 0.00015 21.5 0.9 0.00023 20.9 0.6 1.5 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 EGG41282.1 - 0.0018 18.5 1.3 0.0025 18.1 0.8 1.4 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EGG41282.1 - 0.0019 17.7 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 EGG41282.1 - 0.0082 15.0 0.5 0.14 11.0 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.12 EGG41282.1 - 0.0091 15.4 0.2 0.033 13.6 0.0 1.9 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 EGG41282.1 - 0.01 15.4 4.4 0.017 14.6 1.9 2.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EGG41282.1 - 0.013 15.7 0.9 0.026 14.7 0.6 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 EGG41282.1 - 0.013 14.1 1.3 0.026 13.1 0.1 1.7 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 EGG41282.1 - 0.059 13.2 1.8 0.11 12.4 1.2 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EGG41282.1 - 0.072 12.0 0.3 0.14 11.1 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGG41282.1 - 0.11 12.6 4.5 0.8 9.8 3.1 2.1 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EGG41282.1 - 0.21 12.0 1.3 0.88 10.0 0.9 2.1 1 1 0 1 1 1 0 Miro-like protein S-AdoMet_synt_C PF02773.11 EGG41283.1 - 4.3e-69 230.5 0.0 8.5e-69 229.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EGG41283.1 - 7.6e-53 177.5 0.8 2e-51 172.9 0.0 2.3 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EGG41283.1 - 2.5e-41 139.9 2.4 3.6e-41 139.4 0.2 2.3 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.14 EGG41283.1 - 0.0094 14.4 2.9 0.58 8.5 0.4 2.3 1 1 1 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) NAD_binding_10 PF13460.1 EGG41284.1 - 9.3e-17 61.6 0.0 1.1e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGG41284.1 - 1.1e-11 44.6 0.0 1.4e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG41284.1 - 2.4e-09 36.3 0.6 2.5e-06 26.3 0.3 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG41284.1 - 6.2e-07 28.5 0.0 0.0048 15.8 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 EGG41284.1 - 2.8e-05 23.4 3.2 4.6e-05 22.7 2.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EGG41284.1 - 0.00014 20.9 0.1 0.085 11.7 0.0 3.0 1 1 2 3 3 3 2 Male sterility protein PAC2 PF09754.4 EGG41284.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 PAC2 family Shikimate_DH PF01488.15 EGG41284.1 - 0.0032 17.5 0.4 0.0061 16.6 0.3 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DDE_Tnp_1_3 PF13612.1 EGG41284.1 - 0.014 15.1 0.3 0.014 15.1 0.2 2.9 4 0 0 4 4 4 0 Transposase DDE domain THF_DHG_CYH_C PF02882.14 EGG41284.1 - 0.022 13.8 0.1 0.066 12.2 0.1 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 EGG41284.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1863 PF08937.6 EGG41284.1 - 0.039 13.9 2.2 0.054 13.5 0.9 1.8 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF1699 PF08004.6 EGG41284.1 - 0.054 13.0 3.2 0.086 12.3 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1699) CbiD PF01888.12 EGG41285.1 - 2.3e-87 292.2 1.9 3e-87 291.8 1.4 1.1 1 0 0 1 1 1 1 CbiD DUF3042 PF11240.3 EGG41285.1 - 0.22 11.3 0.1 0.22 11.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) CbiG_N PF11760.3 EGG41286.1 - 5.4e-33 112.5 0.3 8.5e-33 111.9 0.2 1.3 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.11 EGG41286.1 - 9.9e-29 100.0 0.0 1.9e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.3 EGG41286.1 - 2.6e-10 40.4 0.0 6.8e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Cobalamin biosynthesis central region SpoU_sub_bind PF08032.7 EGG41286.1 - 0.033 14.3 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding CbiX PF01903.12 EGG41287.1 - 1.2e-36 124.9 0.0 4.7e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.6 EGG41287.1 - 1.1e-09 37.7 2.0 1.3e-09 37.4 1.4 1.1 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.14 EGG41287.1 - 7.5e-08 31.6 0.1 0.00022 20.3 0.0 2.0 1 1 1 2 2 2 2 Ferrochelatase Prenyltransf PF01255.14 EGG41287.1 - 0.065 12.3 0.4 0.12 11.5 0.3 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase CbiC PF02570.10 EGG41288.1 - 1.2e-73 246.7 0.7 1.4e-73 246.5 0.5 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase GATase_3 PF07685.9 EGG41289.1 - 2e-31 108.6 0.1 3.2e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.18 EGG41289.1 - 1.2e-24 86.8 0.0 2.3e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 EGG41289.1 - 5.9e-12 45.6 0.7 6.3e-09 35.7 0.7 2.6 2 1 0 2 2 2 1 AAA domain SNO PF01174.14 EGG41289.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family CTP_synth_N PF06418.9 EGG41289.1 - 0.0044 16.1 0.0 0.012 14.7 0.0 1.7 1 0 0 1 1 1 1 CTP synthase N-terminus YhjQ PF06564.7 EGG41289.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein DUF1611 PF07755.6 EGG41289.1 - 0.085 11.4 0.1 0.21 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) IstB_IS21 PF01695.12 EGG41289.1 - 0.14 11.5 0.2 0.37 10.1 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CobA_CobO_BtuR PF02572.10 EGG41290.1 - 9.8e-62 207.5 0.1 1.1e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_14 PF13173.1 EGG41290.1 - 0.00054 19.8 0.6 0.0013 18.6 0.4 1.7 1 1 0 1 1 1 1 AAA domain Response_reg PF00072.19 EGG41290.1 - 0.077 13.0 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Response regulator receiver domain AAA_19 PF13245.1 EGG41290.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EGG41290.1 - 0.29 10.5 3.1 2.4 7.5 1.9 2.2 1 1 0 1 1 1 0 AAA domain EIF_2_alpha PF07541.7 EGG41291.1 - 7e-24 83.7 2.7 7.5e-24 83.6 0.4 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EGG41291.1 - 7.7e-13 48.3 0.2 5.7e-12 45.5 0.1 2.4 2 0 0 2 2 2 1 S1 RNA binding domain DUF3782 PF12644.2 EGG41291.1 - 0.013 15.2 0.1 0.17 11.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) EXOSC1 PF10447.4 EGG41291.1 - 0.032 14.1 0.5 0.26 11.2 0.1 2.5 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 MBT PF02820.13 EGG41291.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 mbt repeat Nop10p PF04135.7 EGG41292.1 - 2.2e-23 81.7 3.0 2.3e-23 81.6 2.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family RecR PF02132.10 EGG41292.1 - 0.0018 17.6 0.9 0.0021 17.4 0.7 1.2 1 0 0 1 1 1 1 RecR protein DUF1272 PF06906.6 EGG41292.1 - 0.041 13.7 1.0 0.046 13.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PolC_DP2 PF03833.8 EGG41292.1 - 0.091 10.4 0.3 0.081 10.5 0.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C3HC4_3 PF13920.1 EGG41292.1 - 0.14 11.8 3.0 0.17 11.5 2.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tet_res_leader PF08050.7 EGG41292.1 - 0.21 11.2 0.4 0.21 11.2 0.3 1.6 2 0 0 2 2 2 0 Tetracycline resistance leader peptide DUF329 PF03884.9 EGG41292.1 - 1.7 8.2 4.6 0.97 9.0 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF329) STT3 PF02516.9 EGG41293.1 - 2.6e-38 132.2 37.6 9.9e-38 130.3 26.1 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Sigma_reg_N PF13800.1 EGG41293.1 - 1.4 8.9 12.1 13 5.8 0.3 4.2 3 1 0 3 3 3 0 Sigma factor regulator N-terminal PBP PF01161.15 EGG41294.1 - 1.3e-37 128.8 0.1 1.4e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fcf1 PF04900.7 EGG41295.1 - 4.2e-11 42.8 0.0 5e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Fcf1 BRCT PF00533.21 EGG41295.1 - 0.0029 17.6 1.4 0.018 15.1 0.1 2.4 1 1 2 3 3 3 1 BRCA1 C Terminus (BRCT) domain DUF2482 PF10655.4 EGG41295.1 - 0.049 13.7 0.3 0.1 12.6 0.1 1.6 1 1 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) DUF1132 PF06575.7 EGG41295.1 - 0.19 12.0 1.1 4 7.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1132) GTP_EFTU PF00009.22 EGG41296.1 - 5.9e-41 139.9 0.0 9.5e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGG41296.1 - 8.2e-25 86.6 0.2 4e-24 84.4 0.0 2.2 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGG41296.1 - 8.2e-06 25.8 0.7 5.6e-05 23.1 0.2 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGG41296.1 - 0.00076 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOB1_Zn_bind PF08772.6 EGG41296.1 - 0.01 15.6 0.2 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like FeoB_N PF02421.13 EGG41296.1 - 0.024 13.9 0.3 1.5 8.0 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Ribosomal_S6e PF01092.14 EGG41297.1 - 4.1e-19 68.4 0.1 5.1e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e zf-ribbon_3 PF13248.1 EGG41298.1 - 2e-05 23.6 14.1 0.00059 18.9 4.4 1.8 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGG41298.1 - 7.3e-05 22.1 5.9 0.0062 15.9 1.7 2.3 2 1 0 2 2 2 2 zinc-ribbon domain FYDLN_acid PF09538.5 EGG41298.1 - 0.0016 19.0 2.1 0.0017 18.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-C4_Topoisom PF01396.14 EGG41298.1 - 0.0018 17.7 7.7 0.18 11.3 1.0 2.3 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc-ribbons_6 PF07191.7 EGG41298.1 - 0.012 15.3 6.6 0.37 10.6 4.0 1.9 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.2 EGG41298.1 - 0.015 15.0 7.2 0.056 13.2 5.1 1.5 1 1 0 1 1 1 0 Double zinc ribbon DUF2039 PF10217.4 EGG41298.1 - 0.015 15.2 3.9 0.016 15.2 2.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Ogr_Delta PF04606.7 EGG41298.1 - 0.016 14.8 5.0 0.69 9.6 0.3 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DNA_ligase_ZBD PF03119.11 EGG41298.1 - 0.017 14.8 1.0 0.48 10.1 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Prok-RING_1 PF14446.1 EGG41298.1 - 0.021 14.5 7.0 0.026 14.2 4.9 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-ISL3 PF14690.1 EGG41298.1 - 0.041 13.9 6.4 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 A2L_zn_ribbon PF08792.5 EGG41298.1 - 0.049 13.0 4.5 0.13 11.7 3.1 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS91 PF14319.1 EGG41298.1 - 0.051 13.0 6.3 0.054 13.0 4.3 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain RPA_interact_C PF14768.1 EGG41298.1 - 0.058 13.7 4.2 0.061 13.7 2.9 1.0 1 0 0 1 1 1 0 Replication protein A interacting C-terminal OrfB_Zn_ribbon PF07282.6 EGG41298.1 - 0.071 12.7 5.7 0.086 12.5 3.9 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain GASA PF02704.9 EGG41298.1 - 0.089 12.7 5.1 0.11 12.4 3.5 1.2 1 0 0 1 1 1 0 Gibberellin regulated protein Zn_Tnp_IS1 PF03811.8 EGG41298.1 - 0.091 12.2 6.2 0.12 11.8 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain DUF555 PF04475.7 EGG41298.1 - 0.099 12.6 2.4 0.45 10.5 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF555) TF_Zn_Ribbon PF08271.7 EGG41298.1 - 0.12 11.6 6.6 0.2 11.0 4.5 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding DUF1936 PF09151.5 EGG41298.1 - 0.14 11.6 5.2 3.7 7.1 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1936) zf-TFIIB PF13453.1 EGG41298.1 - 0.15 11.3 8.0 1 8.6 1.5 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_ribbon_recom PF13408.1 EGG41298.1 - 0.15 12.3 5.7 35 4.7 3.9 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zinc_ribbon_5 PF13719.1 EGG41298.1 - 0.17 11.4 4.6 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.1 EGG41298.1 - 0.18 11.6 4.5 4.7 7.0 2.6 2.1 1 1 1 2 2 2 0 YhfH-like protein Ribosomal_S27e PF01667.12 EGG41298.1 - 0.19 11.3 5.5 0.3 10.6 3.8 1.4 1 1 0 1 1 1 0 Ribosomal protein S27 Mu-like_Com PF10122.4 EGG41298.1 - 0.2 10.7 7.6 0.29 10.2 1.2 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com Cys_rich_KTR PF14205.1 EGG41298.1 - 0.28 10.6 7.7 13 5.3 5.3 2.1 1 1 0 1 1 1 0 Cysteine-rich KTR IBR PF01485.16 EGG41298.1 - 0.31 10.9 6.3 0.35 10.7 4.4 1.2 1 0 0 1 1 1 0 IBR domain zf-NADH-PPase PF09297.6 EGG41298.1 - 0.32 10.5 7.2 0.48 9.9 1.9 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.5 EGG41298.1 - 0.36 10.8 8.0 1.8 8.6 0.3 2.3 1 1 1 2 2 2 0 Zinc ribbon domain HypA PF01155.14 EGG41298.1 - 0.38 10.4 4.9 0.42 10.3 3.4 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Nudix_N_2 PF14803.1 EGG41298.1 - 0.51 10.0 4.4 0.63 9.7 0.7 2.2 2 0 0 2 2 2 0 Nudix N-terminal DUF2072 PF09845.4 EGG41298.1 - 0.51 10.2 3.0 0.57 10.1 2.0 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-Mss51 PF13824.1 EGG41298.1 - 0.53 10.1 5.3 0.76 9.6 3.7 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-FPG_IleRS PF06827.9 EGG41298.1 - 0.64 9.7 9.2 3.3 7.4 5.9 2.1 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS DUF329 PF03884.9 EGG41298.1 - 0.66 9.5 7.3 3.8 7.1 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF329) GFA PF04828.9 EGG41298.1 - 0.72 9.8 5.8 0.23 11.4 0.8 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-HIT PF04438.11 EGG41298.1 - 0.72 9.5 9.0 2.1 8.0 0.4 2.3 2 1 0 2 2 2 0 HIT zinc finger RNA_POL_M_15KD PF02150.11 EGG41298.1 - 0.75 9.5 9.8 0.18 11.4 1.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_4 PF13717.1 EGG41298.1 - 0.81 9.4 7.0 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EGG41298.1 - 0.82 9.5 7.2 1.8 8.4 5.1 1.6 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Dynactin_p62 PF05502.8 EGG41298.1 - 0.9 8.2 3.6 0.92 8.1 2.5 1.0 1 0 0 1 1 1 0 Dynactin p62 family Rubredoxin PF00301.15 EGG41298.1 - 0.92 9.4 5.7 13 5.8 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin zf-RING_3 PF14369.1 EGG41298.1 - 0.97 9.4 6.6 1.3 9.0 0.1 2.4 1 1 1 2 2 2 0 zinc-finger Cys_rich_CWC PF14375.1 EGG41298.1 - 1 9.3 7.6 0.46 10.4 0.6 2.2 2 0 0 2 2 2 0 Cysteine-rich CWC Rep_fac-A_C PF08646.5 EGG41298.1 - 1.1 8.9 6.0 1.1 8.9 4.2 1.0 1 0 0 1 1 1 0 Replication factor-A C terminal domain TFIIS_C PF01096.13 EGG41298.1 - 1.1 8.9 8.0 3 7.5 0.8 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-HYPF PF07503.7 EGG41298.1 - 1.4 8.3 5.8 67 3.0 4.0 2.2 1 1 0 1 1 1 0 HypF finger Zn_Tnp_IS1595 PF12760.2 EGG41298.1 - 2.2 8.1 9.1 3.5 7.4 0.7 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-IS66 PF13005.2 EGG41298.1 - 2.5 8.1 8.3 5.5 7.0 0.6 2.1 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF2082 PF09855.4 EGG41298.1 - 3.4 7.5 7.3 4.8 7.1 0.6 2.1 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-Di19 PF05605.7 EGG41298.1 - 3.5 7.8 7.9 1.5 9.0 0.8 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Lar_restr_allev PF14354.1 EGG41298.1 - 3.9 7.8 7.2 17 5.7 5.0 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-LITAF-like PF10601.4 EGG41298.1 - 4.9 7.0 8.3 10 6.0 0.3 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-tcix PF14952.1 EGG41298.1 - 5.9 6.3 7.2 2.3 7.6 0.6 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding PhnA_Zn_Ribbon PF08274.7 EGG41298.1 - 7.1 6.5 8.2 57 3.6 5.7 2.1 1 1 0 1 1 1 0 PhnA Zinc-Ribbon CpXC PF14353.1 EGG41298.1 - 9.4 6.2 7.0 23 4.9 0.6 2.0 1 1 0 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.1 EGG41299.1 - 0.00014 21.4 2.4 0.0004 20.0 1.7 1.7 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG41299.1 - 0.00026 20.5 2.7 0.00066 19.2 1.9 1.7 1 1 0 1 1 1 1 zinc-ribbon domain IBR PF01485.16 EGG41299.1 - 0.0019 18.0 1.0 0.003 17.4 0.7 1.3 1 0 0 1 1 1 1 IBR domain CpXC PF14353.1 EGG41299.1 - 0.0098 15.8 3.5 0.016 15.1 0.1 2.0 1 1 1 2 2 2 1 CpXC protein OrfB_Zn_ribbon PF07282.6 EGG41299.1 - 0.012 15.2 0.2 0.015 14.9 0.2 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EGG41299.1 - 0.012 14.7 4.0 0.13 11.5 3.1 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 EGG41299.1 - 0.015 14.7 1.6 0.94 9.0 0.1 2.1 2 0 0 2 2 2 0 InsA N-terminal domain zf-ISL3 PF14690.1 EGG41299.1 - 0.029 14.4 1.4 2.9 8.0 0.1 2.1 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_4 PF13894.1 EGG41299.1 - 0.034 14.4 0.9 3 8.3 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Prok-RING_1 PF14446.1 EGG41299.1 - 0.048 13.4 1.9 0.064 12.9 1.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_Tnp_IS91 PF14319.1 EGG41299.1 - 0.066 12.7 0.1 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zinc_ribbon_2 PF13240.1 EGG41299.1 - 0.072 12.6 3.2 0.15 11.5 2.2 1.6 1 1 0 1 1 1 0 zinc-ribbon domain DUF329 PF03884.9 EGG41299.1 - 0.079 12.5 3.1 3.3 7.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF329) Ribosomal_S27e PF01667.12 EGG41299.1 - 0.079 12.5 2.4 0.2 11.1 1.7 1.6 1 1 0 1 1 1 0 Ribosomal protein S27 RIG-I_C-RD PF11648.3 EGG41299.1 - 0.08 12.8 0.3 0.091 12.6 0.2 1.0 1 0 0 1 1 1 0 C-terminal domain of RIG-I zinc-ribbons_6 PF07191.7 EGG41299.1 - 0.089 12.5 0.5 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons Lar_restr_allev PF14354.1 EGG41299.1 - 0.1 12.9 1.0 0.2 11.9 0.7 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EGG41299.1 - 0.1 12.4 0.2 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.5 EGG41299.1 - 0.14 12.0 2.7 0.25 11.3 1.9 1.4 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 EGG41299.1 - 0.15 11.9 1.4 0.29 10.9 0.9 1.5 1 1 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 EGG41299.1 - 0.17 11.7 1.7 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-CHCC PF10276.4 EGG41299.1 - 0.19 11.5 0.2 0.19 11.5 0.1 1.8 3 0 0 3 3 1 0 Zinc-finger domain Mu-like_Com PF10122.4 EGG41299.1 - 0.24 10.4 1.4 0.45 9.6 1.0 1.5 1 1 0 1 1 1 0 Mu-like prophage protein Com zf-Di19 PF05605.7 EGG41299.1 - 0.25 11.5 4.4 0.49 10.5 0.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EGG41299.1 - 0.29 11.5 4.6 4 7.9 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EGG41299.1 - 0.29 10.9 2.4 1.4 8.7 0.0 2.1 1 1 1 2 2 2 0 BED zinc finger Auto_anti-p27 PF06677.7 EGG41299.1 - 0.36 10.6 1.8 0.47 10.2 1.2 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) UPF0547 PF10571.4 EGG41299.1 - 2 8.1 6.7 10 5.9 4.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 EGG41299.1 - 2.6 8.0 5.0 47 4.0 3.5 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-RING_3 PF14369.1 EGG41299.1 - 2.6 8.0 5.6 2.1 8.4 0.3 2.1 1 1 1 2 2 2 0 zinc-finger zf-RING_4 PF14570.1 EGG41299.1 - 7.1 6.3 7.2 30 4.2 1.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TPR_11 PF13414.1 EGG41300.1 - 3.6e-20 71.3 8.7 1.4e-12 47.0 2.6 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGG41300.1 - 2.4e-14 52.2 16.0 1.9e-08 33.5 1.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGG41300.1 - 5.8e-12 44.5 10.6 1.8e-06 27.3 0.3 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG41300.1 - 2.8e-11 42.6 12.5 0.00046 20.1 1.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGG41300.1 - 1.2e-08 34.7 3.9 1.4e-06 28.0 0.3 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGG41300.1 - 2.6e-07 31.1 0.0 0.0071 17.0 0.0 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGG41300.1 - 2.6e-07 30.8 0.3 0.017 15.4 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG41300.1 - 2.2e-06 27.7 0.0 0.047 14.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG41300.1 - 6e-05 22.5 24.5 0.0011 18.5 1.3 5.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGG41300.1 - 9.8e-05 22.1 0.0 0.00059 19.6 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG41300.1 - 0.00021 21.5 2.0 3.1 8.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Peptidase_C39_2 PF13529.1 EGG41300.1 - 0.0027 18.0 0.0 0.0065 16.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.10 EGG41300.1 - 0.012 15.4 0.0 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase C39 family GATase PF00117.23 EGG41301.1 - 3.5e-21 75.5 0.0 4e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG41301.1 - 6.7e-09 35.5 0.0 6.3e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 EGG41301.1 - 0.015 14.9 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 SNO glutamine amidotransferase family UPF0182 PF03699.8 EGG41302.1 - 6.3e-30 103.7 21.2 1.7e-28 99.0 14.7 2.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) DNA_primase_S PF01896.14 EGG41303.1 - 2.9e-18 66.0 0.8 8e-17 61.3 0.6 2.3 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit stn_TNFRSF12A PF12191.3 EGG41303.1 - 0.0048 16.9 3.5 0.0089 16.0 2.4 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PolC_DP2 PF03833.8 EGG41303.1 - 0.19 9.3 4.1 0.26 8.8 2.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DNA_primase_lrg PF04104.9 EGG41304.1 - 1.4e-26 93.3 0.0 3.5e-26 92.0 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit AP_endonuc_2 PF01261.19 EGG41305.1 - 2.6e-32 111.8 0.0 9.3e-32 110.0 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF3445 PF11927.3 EGG41305.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3445) tRNA-synt_2b PF00587.20 EGG41306.1 - 4.1e-48 163.2 0.1 1e-47 161.9 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGG41306.1 - 2.9e-16 59.1 0.2 7.3e-16 57.8 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain Zn-ribbon_8 PF09723.5 EGG41306.1 - 0.034 14.1 0.7 8.1 6.4 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EGG41306.1 - 0.13 11.8 3.5 3.6 7.2 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG41306.1 - 0.18 11.4 3.0 6.8 6.4 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain HemolysinCabind PF00353.14 EGG41307.1 - 2.4e-15 55.3 84.3 0.00028 20.9 5.5 7.8 2 1 7 11 11 11 9 Hemolysin-type calcium-binding repeat (2 copies) RNA_polI_A34 PF08208.6 EGG41307.1 - 0.1 12.2 16.9 0.12 11.9 11.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Kinocilin PF15033.1 EGG41307.1 - 2 7.9 4.0 4 7.0 0.1 2.6 1 1 1 2 2 2 0 Kinocilin protein Collagen PF01391.13 EGG41307.1 - 6 6.4 22.1 1e+03 -0.7 15.3 3.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Fibrillarin PF01269.12 EGG41308.1 - 1.1e-86 289.4 0.4 1.2e-86 289.3 0.3 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EGG41308.1 - 3.4e-05 23.4 0.0 4.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EGG41308.1 - 0.00096 18.7 0.0 0.0014 18.2 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EGG41308.1 - 0.0058 15.7 0.0 0.046 12.7 0.0 2.0 1 1 1 2 2 2 1 Putative methyltransferase DUF4651 PF15513.1 EGG41308.1 - 0.023 14.1 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) RNase_HII PF01351.13 EGG41309.1 - 4.3e-20 72.1 0.1 5.1e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII RNase_HII PF01351.13 EGG41310.1 - 1.9e-16 60.2 0.4 2.1e-16 60.1 0.3 1.0 1 0 0 1 1 1 1 Ribonuclease HII TRM PF02005.11 EGG41311.1 - 4.2e-83 279.3 0.0 4.8e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EGG41311.1 - 6e-05 22.6 0.1 0.00099 18.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EGG41311.1 - 0.0017 17.9 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein HTH_24 PF13412.1 EGG41311.1 - 0.0052 16.1 0.0 0.057 12.8 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 EGG41311.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.17 EGG41311.1 - 0.027 14.1 0.0 0.087 12.5 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_Mga PF08280.6 EGG41311.1 - 0.055 13.2 0.1 6.3 6.6 0.0 2.6 1 1 1 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain MTS PF05175.9 EGG41311.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EGG41312.1 - 1.8e-50 171.4 0.0 2.1e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGG41312.1 - 2.6e-05 23.8 0.0 4.3e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41312.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG41312.1 - 0.0071 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EGG41312.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41312.1 - 0.035 14.6 0.0 0.065 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 EGG41312.1 - 0.037 13.4 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 NOL1/NOP2/sun family Ubie_methyltran PF01209.13 EGG41312.1 - 0.084 11.9 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RNA_pol_Rpc34 PF05158.7 EGG41313.1 - 5.4e-06 25.8 0.2 1.1e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR PF01047.17 EGG41313.1 - 0.0079 15.8 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 MarR family RPA_C PF08784.6 EGG41313.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Replication protein A C terminal PBCV_basic_adap PF08789.5 EGG41314.1 - 2.5 7.8 8.7 2.4 7.8 1.9 2.2 1 1 1 2 2 2 0 PBCV-specific basic adaptor domain AAA_15 PF13175.1 EGG41316.1 - 1.6e-16 60.4 23.2 1.1e-10 41.1 7.3 4.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 EGG41316.1 - 8.7e-11 42.3 28.7 1.6e-10 41.4 10.2 4.1 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGG41316.1 - 0.00024 21.4 10.9 0.00024 21.4 7.5 2.6 2 1 0 2 2 2 1 AAA domain DUF2813 PF11398.3 EGG41316.1 - 0.0019 17.3 0.2 1.1 8.2 0.0 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2813) AAA_29 PF13555.1 EGG41316.1 - 0.0022 17.4 0.1 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGG41316.1 - 0.0022 18.2 1.3 0.0066 16.7 0.1 2.4 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 EGG41316.1 - 0.074 13.0 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase A2M_N PF01835.14 EGG41317.1 - 3e-23 81.9 2.2 1.4e-06 28.5 0.0 6.3 6 1 1 7 7 7 4 MG2 domain FlgD_ig PF13860.1 EGG41317.1 - 1.3e-08 34.3 9.8 0.022 14.4 0.0 5.6 5 0 0 5 5 5 3 FlgD Ig-like domain DUF1973 PF09315.6 EGG41317.1 - 1.3e-05 24.7 0.3 0.00037 19.9 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1973) Cna_B PF05738.8 EGG41317.1 - 4.7e-05 23.0 6.1 0.48 10.2 0.2 5.0 4 0 0 4 4 4 2 Cna protein B-type domain CarboxypepD_reg PF13620.1 EGG41317.1 - 0.0039 17.2 12.2 0.0086 16.1 0.5 5.8 6 1 0 6 6 6 1 Carboxypeptidase regulatory-like domain Pribosyltran PF00156.22 EGG41318.1 - 4e-17 62.0 0.1 5.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGG41318.1 - 0.0049 16.1 0.0 0.0061 15.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PNP_UDP_1 PF01048.15 EGG41319.1 - 3.6e-42 143.9 0.0 4.1e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3215 PF11503.3 EGG41320.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) zf-met PF12874.2 EGG41321.1 - 0.063 13.5 0.4 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TrmB PF01978.14 EGG41322.1 - 0.00059 19.4 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Colicin_immun PF09204.5 EGG41322.1 - 0.11 12.6 0.1 1.6 8.8 0.0 2.1 1 1 0 2 2 2 0 Bacterial self-protective colicin-like immunity BaxI_1 PF12811.2 EGG41323.1 - 0.018 14.1 1.4 0.019 14.1 1.0 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like DIPSY PF11763.3 EGG41324.1 - 0.041 13.6 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal GvpH PF05455.6 EGG41324.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.5 1 1 1 2 2 2 0 GvpH TP6A_N PF04406.9 EGG41325.1 - 2.5e-19 68.6 0.1 4.5e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SusD-like_2 PF12771.2 EGG41325.1 - 0.087 11.1 0.1 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Toprim PF01751.17 EGG41325.1 - 0.098 12.6 0.3 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Toprim domain DUF4018 PF13210.1 EGG41325.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Topo-VIb_trans PF09239.6 EGG41326.1 - 7.6e-58 194.5 0.0 1.2e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.1 EGG41326.1 - 2e-07 30.7 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGG41326.1 - 5.2e-07 29.3 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KH_1 PF00013.24 EGG41327.1 - 3.6e-14 52.1 12.1 3.6e-07 29.7 1.0 2.7 2 1 1 3 3 3 2 KH domain KH_3 PF13014.1 EGG41327.1 - 1.4e-06 27.8 12.1 0.0031 17.1 1.5 3.3 3 0 0 3 3 3 2 KH domain KH_2 PF07650.12 EGG41327.1 - 0.014 14.9 5.7 0.58 9.7 0.6 2.9 2 1 0 2 2 2 0 KH domain RIO1 PF01163.17 EGG41328.1 - 3.2e-52 176.6 0.0 4.2e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGG41328.1 - 0.0024 17.6 0.0 1.3 8.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family BBS2_Mid PF14783.1 EGG41328.1 - 0.038 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Kdo PF06293.9 EGG41328.1 - 0.16 11.0 0.0 2.1 7.3 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF424 PF04242.8 EGG41329.1 - 9.8e-22 76.8 0.4 1.1e-21 76.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) DUF4284 PF14112.1 EGG41329.1 - 0.036 14.5 0.2 0.038 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) DUF1874 PF08960.5 EGG41329.1 - 0.1 12.3 0.4 0.21 11.3 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1874) eIF-5_eIF-2B PF01873.12 EGG41330.1 - 6.5e-24 83.9 0.0 7.2e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Elf1 PF05129.8 EGG41330.1 - 0.04 13.6 0.4 0.063 12.9 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.7 EGG41330.1 - 0.13 11.5 0.5 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding GATA PF00320.22 EGG41330.1 - 0.22 10.9 1.3 0.66 9.3 0.9 1.8 1 1 0 1 1 1 0 GATA zinc finger Antiterm PF03589.8 EGG41331.1 - 0.001 19.1 0.6 0.0011 19.0 0.4 1.1 1 0 0 1 1 1 1 Antitermination protein zinc_ribbon_2 PF13240.1 EGG41331.1 - 0.0044 16.4 1.5 0.019 14.4 1.1 1.9 1 1 0 1 1 1 1 zinc-ribbon domain HypA PF01155.14 EGG41331.1 - 0.0088 15.7 0.7 0.0099 15.5 0.5 1.0 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Auto_anti-p27 PF06677.7 EGG41331.1 - 0.029 14.1 2.1 0.11 12.2 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.2 EGG41331.1 - 0.032 14.0 3.4 0.059 13.1 2.4 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGG41331.1 - 0.039 13.1 3.4 0.11 11.7 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EGG41331.1 - 0.05 13.5 2.5 0.26 11.2 1.9 1.7 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2072 PF09845.4 EGG41331.1 - 0.12 12.3 1.4 0.18 11.6 1.0 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-ISL3 PF14690.1 EGG41331.1 - 0.14 12.1 4.0 1.4 9.0 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C4_Topoisom PF01396.14 EGG41331.1 - 0.15 11.6 1.8 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_5 PF13719.1 EGG41331.1 - 0.18 11.3 7.0 0.8 9.3 4.8 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG41331.1 - 0.23 11.1 7.2 1.1 9.0 5.0 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGG41331.1 - 0.33 10.9 3.6 2.9 7.9 2.5 2.0 1 1 0 1 1 1 0 Zinc ribbon domain DUF2082 PF09855.4 EGG41331.1 - 0.44 10.4 2.7 1.5 8.7 0.1 2.0 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C3HC4_3 PF13920.1 EGG41331.1 - 0.59 9.8 3.9 3.1 7.5 2.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-tcix PF14952.1 EGG41331.1 - 0.62 9.4 4.2 0.17 11.2 0.5 1.8 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding ADK_lid PF05191.9 EGG41331.1 - 0.81 9.4 4.6 4.1 7.1 3.3 2.0 1 1 1 2 2 2 0 Adenylate kinase, active site lid DUF2387 PF09526.5 EGG41331.1 - 4.1 7.3 5.9 3.4 7.6 0.2 2.0 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) DUF1610 PF07754.6 EGG41331.1 - 4.6 7.4 6.3 0.89 9.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-RanBP PF00641.13 EGG41331.1 - 6.1 6.0 6.1 16 4.6 0.7 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF1704 PF08014.6 EGG41332.1 - 0.031 13.2 0.0 0.058 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1704) RE_XamI PF09572.5 EGG41332.1 - 0.093 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease GTP_EFTU_D3 PF03143.12 EGG41332.1 - 0.1 12.8 0.5 3.7 7.7 0.3 2.3 1 1 0 1 1 1 0 Elongation factor Tu C-terminal domain UPF0118 PF01594.11 EGG41332.1 - 0.12 11.3 0.8 0.2 10.6 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function DUF20 WSN PF02206.13 EGG41332.1 - 0.2 11.4 1.5 6 6.6 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF373 PF04123.8 EGG41333.1 - 6.2e-102 341.1 15.6 7.3e-102 340.9 10.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF4229 PF14012.1 EGG41333.1 - 5.5 6.9 16.1 0.51 10.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) SPC12 PF06645.8 EGG41333.1 - 9.6 6.1 8.5 0.62 9.9 0.4 2.7 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Prenyltransf PF01255.14 EGG41334.1 - 3e-77 258.7 0.1 3.3e-77 258.5 0.1 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase GxGYxYP PF14323.1 EGG41334.1 - 0.022 13.5 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function NUDIX PF00293.23 EGG41335.1 - 1.2e-17 63.7 0.1 1.4e-17 63.5 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.1 EGG41335.1 - 0.076 12.5 0.1 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 DBC1 DUF1912 PF08930.5 EGG41335.1 - 0.7 10.0 3.2 11 6.1 0.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1912) OMPdecase PF00215.19 EGG41336.1 - 4.1e-28 98.3 0.0 4.9e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Adenylsucc_synt PF00709.16 EGG41338.1 - 7.5e-87 291.7 1.5 1.2e-40 139.5 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase Annexin PF00191.15 EGG41339.1 - 0.0039 17.0 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 Annexin Catalase-rel PF06628.7 EGG41339.1 - 0.036 13.9 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Catalase-related immune-responsive Iron_traffic PF04362.9 EGG41340.1 - 1.1e-08 34.3 0.3 1.9e-08 33.6 0.2 1.5 1 1 0 1 1 1 1 Bacterial Fe(2+) trafficking zinc_ribbon_2 PF13240.1 EGG41340.1 - 0.017 14.5 0.7 0.039 13.4 0.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain PIRT PF15099.1 EGG41342.1 - 0.00015 20.9 3.8 0.00044 19.4 0.3 2.2 1 1 1 2 2 2 1 Phosphoinositide-interacting protein family MerC PF03203.9 EGG41342.1 - 0.13 12.6 5.7 1.3 9.3 1.5 2.2 2 0 0 2 2 2 0 MerC mercury resistance protein DUF4231 PF14015.1 EGG41342.1 - 6 6.8 5.7 5.5 7.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HTH_45 PF14947.1 EGG41343.1 - 1.3e-12 47.2 0.2 1.8e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 EGG41343.1 - 2.5e-07 30.2 0.0 3.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.5 EGG41343.1 - 5.6e-05 22.6 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 EGG41343.1 - 0.0001 21.6 0.2 0.0002 20.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EGG41343.1 - 0.00028 20.5 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 EGG41343.1 - 0.00029 20.4 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 EGG41343.1 - 0.00085 19.5 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain RPA_C PF08784.6 EGG41343.1 - 0.0014 19.0 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 Replication protein A C terminal RP-C PF03428.8 EGG41343.1 - 0.0015 18.0 0.1 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Replication protein C N-terminal domain Mrr_N PF14338.1 EGG41343.1 - 0.0015 18.5 0.0 0.0021 18.1 0.0 1.4 1 1 0 1 1 1 1 Mrr N-terminal domain HTH_34 PF13601.1 EGG41343.1 - 0.0037 17.2 0.1 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.1 EGG41343.1 - 0.0048 16.5 0.1 0.007 15.9 0.0 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4364) RQC PF09382.5 EGG41343.1 - 0.0067 16.1 0.1 0.0075 15.9 0.0 1.1 1 0 0 1 1 1 1 RQC domain FeoC PF09012.5 EGG41343.1 - 0.0069 16.0 0.0 0.0079 15.8 0.0 1.1 1 0 0 1 1 1 1 FeoC like transcriptional regulator RNA_pol_Rpc34 PF05158.7 EGG41343.1 - 0.0095 15.1 0.1 0.0098 15.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_20 PF12840.2 EGG41343.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.15 EGG41343.1 - 0.016 15.3 0.1 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator DUF2250 PF10007.4 EGG41343.1 - 0.018 14.9 0.1 0.039 13.8 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_Crp_2 PF13545.1 EGG41343.1 - 0.027 14.2 0.2 0.08 12.7 0.1 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_5 PF01022.15 EGG41343.1 - 0.051 13.2 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family PadR PF03551.9 EGG41343.1 - 0.051 13.3 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Ftsk_gamma PF09397.5 EGG41343.1 - 0.066 12.9 0.1 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Ftsk gamma domain Linker_histone PF00538.14 EGG41343.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 linker histone H1 and H5 family CENP-B_N PF04218.8 EGG41343.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Mga PF05043.8 EGG41343.1 - 0.14 12.4 1.0 0.63 10.3 0.2 2.1 1 1 1 2 2 2 0 Mga helix-turn-helix domain THUMP PF02926.12 EGG41346.1 - 1.1e-13 51.3 1.8 1.2e-13 51.1 1.2 1.1 1 0 0 1 1 1 1 THUMP domain DEC-1_N PF04625.8 EGG41346.1 - 0.0039 15.9 0.0 0.0043 15.7 0.0 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region DUF1394 PF07159.7 EGG41346.1 - 0.085 11.9 0.1 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) HSBP1 PF06825.7 EGG41346.1 - 0.2 11.2 2.8 0.34 10.5 0.2 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ThiS PF02597.15 EGG41347.1 - 2e-07 31.3 0.1 7.9e-07 29.4 0.0 2.1 3 0 0 3 3 3 1 ThiS family CGI-121 PF08617.5 EGG41347.1 - 8.8e-07 28.7 3.5 2.3e-06 27.3 2.4 1.7 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Urm1 PF09138.6 EGG41347.1 - 0.0052 16.8 3.0 0.0079 16.2 0.4 2.6 2 2 1 3 3 3 1 Urm1 (Ubiquitin related modifier) Ribosomal_S17e PF00833.13 EGG41348.1 - 1.5e-20 73.1 2.0 2e-20 72.7 1.4 1.2 1 0 0 1 1 1 1 Ribosomal S17 DUF4201 PF13870.1 EGG41348.1 - 0.004 16.6 2.5 0.0048 16.3 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) TatD_DNase PF01026.16 EGG41349.1 - 3.1e-39 134.7 0.0 3.4e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase BP28CT PF08146.7 EGG41349.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 BP28CT (NUC211) domain CBFD_NFYB_HMF PF00808.18 EGG41350.1 - 4.9e-14 52.1 0.4 5.3e-14 52.0 0.3 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGG41350.1 - 4.7e-09 36.2 0.2 5.4e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG41350.1 - 2.3e-05 24.4 0.0 2.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EGG41350.1 - 0.00054 19.6 0.0 0.00063 19.4 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EGG41350.1 - 0.0009 19.0 0.0 0.00092 18.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 EGG41350.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAF PF02969.12 EGG41350.1 - 0.0037 17.1 0.5 0.0043 16.9 0.3 1.1 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.11 EGG41350.1 - 0.024 14.4 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1931 PF09123.6 EGG41350.1 - 0.043 13.7 0.2 0.049 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) TFIIB PF00382.14 EGG41350.1 - 0.044 13.5 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Transcription factor TFIIB repeat CENP-T PF15511.1 EGG41350.1 - 0.07 12.3 0.3 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MR_MLE_N PF02746.11 EGG41350.1 - 0.074 13.0 0.1 0.082 12.9 0.1 1.1 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Nckap1 PF09735.4 EGG41353.1 - 4.7e-05 21.1 1.0 6.2e-05 20.7 0.4 1.3 1 1 0 1 1 1 1 Membrane-associated apoptosis protein Phage_hub_GP28 PF11110.3 EGG41353.1 - 0.035 13.7 0.1 0.99 9.0 0.0 2.4 2 0 0 2 2 2 0 Baseplate hub distal subunit DUF2799 PF10973.3 EGG41355.1 - 0.007 16.3 2.4 0.0084 16.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2799) DUF4428 PF14471.1 EGG41355.1 - 0.01 15.5 5.5 0.013 15.2 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF3699 PF12480.3 EGG41355.1 - 0.098 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) zf-C3HC4_3 PF13920.1 EGG41355.1 - 0.63 9.7 6.0 1 9.0 4.1 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COX17 PF05051.8 EGG41355.1 - 7.6 6.6 9.2 0.33 11.0 1.3 2.1 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF2431 PF10354.4 EGG41356.1 - 0.076 12.9 0.0 0.081 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF2130 PF09903.4 EGG41357.1 - 2.4e-19 69.1 5.2 2.4e-19 69.1 3.6 2.9 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2130) Mer2 PF09074.5 EGG41357.1 - 0.0021 18.0 4.5 0.0021 18.0 3.1 3.1 2 1 1 3 3 3 2 Mer2 AAA_13 PF13166.1 EGG41357.1 - 0.058 11.8 37.4 0.025 13.0 20.3 2.1 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 EGG41357.1 - 0.41 7.8 36.8 0.02 12.2 19.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 EGG41357.1 - 0.47 9.8 40.2 0.16 11.4 13.8 3.1 2 1 1 3 3 3 0 Intermediate filament protein Y_phosphatase3 PF13350.1 EGG41357.1 - 5.6 7.1 9.1 0.87 9.8 2.0 2.7 3 1 1 4 4 4 0 Tyrosine phosphatase family FA_synthesis PF02504.10 EGG41358.1 - 0.21 10.3 0.6 0.24 10.2 0.4 1.0 1 0 0 1 1 1 0 Fatty acid synthesis protein DUF501 PF04417.7 EGG41358.1 - 0.4 10.5 3.0 0.61 9.9 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF501) DUF2435 PF10363.4 EGG41359.1 - 0.052 13.4 0.3 1.7 8.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2435) HSDR_N PF04313.9 EGG41360.1 - 2.7e-27 95.7 0.6 1.3e-26 93.5 0.0 2.3 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.10 EGG41360.1 - 9.9e-15 54.8 0.0 9.9e-15 54.8 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG41360.1 - 0.00028 20.6 0.0 0.00083 19.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGG41360.1 - 0.06 13.4 0.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2321 PF10083.4 EGG41360.1 - 0.098 12.1 0.3 0.35 10.3 0.2 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Prp18 PF02840.10 EGG41360.1 - 0.14 11.9 3.9 1 9.1 0.6 2.6 2 0 0 2 2 2 0 Prp18 domain Cas_Cas02710 PF09670.5 EGG41361.1 - 1.8e-07 30.1 0.1 2.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Cas_APE2256 PF09651.5 EGG41361.1 - 0.00042 20.0 0.0 0.00088 18.9 0.0 1.6 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_APE2256) UCR_Fe-S_N PF10399.4 EGG41361.1 - 0.0043 16.1 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SBP_bac_1 PF01547.20 EGG41361.1 - 0.024 14.4 0.2 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cas_NE0113 PF09623.5 EGG41361.1 - 0.13 11.7 0.1 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) HSDR_N_2 PF13588.1 EGG41362.1 - 2.2e-11 43.5 1.9 5.9e-11 42.1 1.3 1.7 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) HsdM_N PF12161.3 EGG41362.1 - 6.4e-06 26.6 4.3 1.2e-05 25.7 1.3 2.8 2 1 0 2 2 2 1 HsdM N-terminal domain Methyltransf_26 PF13659.1 EGG41362.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3568 PF12092.3 EGG41362.1 - 1.4 8.6 5.2 7.7 6.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) HmuY PF14064.1 EGG41363.1 - 0.052 13.5 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 HmuY protein APP_E2 PF12925.2 EGG41363.1 - 0.065 12.8 0.9 0.083 12.4 0.1 1.5 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein PDDEXK_1 PF12705.2 EGG41364.1 - 2.3e-11 43.5 0.5 2.8e-11 43.2 0.3 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EGG41364.1 - 7.9e-06 25.8 2.0 1.1e-05 25.3 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF83 DUF3799 PF12684.2 EGG41364.1 - 9.1e-06 25.1 3.2 1.2e-05 24.7 2.2 1.1 1 0 0 1 1 1 1 PDDEXK-like domain of unknown function (DUF3799) HNH_3 PF13392.1 EGG41365.1 - 8.8e-06 25.0 1.7 1.8e-05 24.0 1.2 1.5 1 0 0 1 1 1 1 HNH endonuclease HTH_DeoR PF08220.7 EGG41365.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HNH PF01844.18 EGG41365.1 - 0.023 14.5 5.5 0.044 13.6 3.8 1.5 1 1 0 1 1 1 0 HNH endonuclease Phage_integrase PF00589.17 EGG41366.1 - 3.6e-15 56.0 0.1 6.3e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 EGG41366.1 - 0.0022 18.0 0.5 0.14 12.3 0.0 3.3 3 1 1 4 4 4 2 Phage integrase, N-terminal SAM-like domain DUF2680 PF10925.3 EGG41366.1 - 0.054 13.3 0.3 0.18 11.6 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Wbp11 PF09429.5 EGG41366.1 - 0.36 10.8 4.5 1.4 8.9 0.2 2.7 2 0 0 2 2 2 0 WW domain binding protein 11 Cupredoxin_1 PF13473.1 EGG41367.1 - 5.7e-11 42.2 0.0 7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 EGG41367.1 - 4.7e-09 36.3 0.0 8.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family AIPR PF10592.4 EGG41368.1 - 1.5e-65 221.5 7.7 1.5e-65 221.5 5.3 2.6 3 0 0 3 3 3 1 AIPR protein HTH_45 PF14947.1 EGG41370.1 - 6.3e-18 64.3 0.5 7.6e-18 64.1 0.3 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 EGG41370.1 - 0.0019 17.8 0.3 0.0026 17.4 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4364) Mrr_N PF14338.1 EGG41370.1 - 0.0021 18.1 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Mrr N-terminal domain RNA_pol_Rpc34 PF05158.7 EGG41370.1 - 0.0043 16.2 0.1 0.0051 16.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_34 PF13601.1 EGG41370.1 - 0.0052 16.7 0.3 0.0074 16.2 0.2 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.15 EGG41370.1 - 0.0077 16.3 0.2 0.014 15.4 0.1 1.5 2 0 0 2 2 2 1 Transcriptional regulator Mannosyl_trans2 PF04188.8 EGG41370.1 - 0.013 14.5 0.0 0.015 14.2 0.0 1.0 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V)) RPA_C PF08784.6 EGG41370.1 - 0.018 15.4 0.1 0.023 15.0 0.1 1.1 1 0 0 1 1 1 0 Replication protein A C terminal PadR PF03551.9 EGG41370.1 - 0.02 14.6 0.1 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PilN PF05137.8 EGG41370.1 - 0.044 13.6 0.2 0.086 12.6 0.1 1.6 1 1 0 1 1 1 0 Fimbrial assembly protein (PilN) Ribosomal_S19e PF01090.14 EGG41370.1 - 0.055 12.8 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e DUF4393 PF14337.1 EGG41370.1 - 0.06 12.7 0.1 0.064 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) TrmB PF01978.14 EGG41370.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB YjcQ PF09639.5 EGG41370.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 YjcQ protein ABC2_membrane_5 PF13346.1 EGG41371.1 - 0.059 12.6 0.3 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 7TM-7TMR_HD PF07698.6 EGG41371.1 - 0.082 12.3 0.1 0.096 12.1 0.1 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Ycf9 PF01737.12 EGG41371.1 - 0.24 10.8 1.2 0.56 9.6 0.8 1.7 1 1 1 2 2 2 0 YCF9 UPF0104 PF03706.8 EGG41372.1 - 0.036 13.3 0.0 0.037 13.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) PGM_PMM_I PF02878.11 EGG41373.1 - 4.2e-24 84.5 0.0 1.2e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGG41373.1 - 2.6e-15 56.4 0.1 1.3e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGG41373.1 - 1.4e-13 51.0 0.0 3.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGG41373.1 - 2e-07 30.9 0.2 7.7e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1938 PF09153.5 EGG41373.1 - 0.02 14.6 0.1 0.02 14.6 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1938) AAA_10 PF12846.2 EGG41373.1 - 0.036 13.5 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Latrotoxin_C PF15658.1 EGG41373.1 - 0.067 13.0 2.1 0.11 12.3 0.5 2.1 2 0 0 2 2 2 0 Latrotoxin C-terminal domain PD40 PF07676.7 EGG41373.1 - 0.11 12.1 0.0 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AIRS PF00586.19 EGG41374.1 - 1.6e-11 44.2 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.17 EGG41374.1 - 1.8e-06 28.0 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain SUD-M PF11633.3 EGG41374.1 - 0.028 13.7 0.1 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Single-stranded poly(A) binding domain DUF2567 PF10821.3 EGG41375.1 - 0.028 13.9 0.0 0.15 11.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2567) Ribosomal_S11 PF00411.14 EGG41376.1 - 8.1e-38 128.9 0.7 1e-37 128.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF4247 PF14042.1 EGG41376.1 - 0.077 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) HJURP_C PF12347.3 EGG41377.1 - 0.13 11.8 0.1 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat EF-1_beta_acid PF10587.4 EGG41378.1 - 0.0031 17.6 1.6 0.0054 16.8 1.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region dsDNA_bind PF01984.15 EGG41378.1 - 0.005 16.8 0.5 0.006 16.5 0.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain RtcB PF01139.12 EGG41379.1 - 1.6e-152 508.4 0.1 1.8e-152 508.2 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF3492 PF11997.3 EGG41379.1 - 0.056 12.9 0.1 0.091 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Complex1_LYR PF05347.10 EGG41379.1 - 0.057 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) FIBP PF05427.6 EGG41379.1 - 0.063 12.5 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) DUF1717 PF05414.6 EGG41380.1 - 0.078 13.4 0.2 0.083 13.3 0.2 1.1 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) DUF1825 PF08855.5 EGG41384.1 - 0.019 14.9 3.4 0.17 11.8 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) Usp PF00582.21 EGG41384.1 - 0.38 10.9 2.4 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 Universal stress protein family DUF4398 PF14346.1 EGG41384.1 - 0.4 10.7 3.6 1.7 8.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) HEPN PF05168.9 EGG41384.1 - 0.57 10.0 4.4 0.47 10.3 0.1 2.8 2 2 1 3 3 3 0 HEPN domain DAGK_prokar PF01219.14 EGG41384.1 - 1 9.0 4.7 1 8.9 1.4 2.2 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Lyase_1 PF00206.15 EGG41385.1 - 9.2e-50 169.5 1.3 1.4e-49 168.9 0.9 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EGG41385.1 - 2.9e-19 68.8 0.0 7.9e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Asn_synthase PF00733.16 EGG41386.1 - 7.2e-31 107.6 0.0 1.7e-30 106.4 0.0 1.5 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 EGG41386.1 - 2.9e-07 29.6 0.1 2.1e-06 26.8 0.0 2.0 2 1 0 2 2 2 1 NAD synthase QueC PF06508.8 EGG41386.1 - 0.00066 19.0 0.1 0.0018 17.6 0.1 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF2683 PF10884.3 EGG41386.1 - 0.1 12.5 1.0 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Pterin_4a PF01329.14 EGG41387.1 - 2.5e-33 113.6 0.2 2.7e-33 113.6 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 EGG41387.1 - 0.0045 16.8 0.1 0.011 15.6 0.1 1.6 1 1 1 2 2 2 1 Translation-initiation factor 2 PTPS PF01242.14 EGG41388.1 - 2.7e-20 72.2 0.0 7.2e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase tRNA-synt_1 PF00133.17 EGG41389.1 - 1.8e-108 363.1 0.5 1.2e-107 360.3 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGG41389.1 - 2.5e-31 108.4 2.6 2.5e-31 108.4 1.8 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGG41389.1 - 3.9e-25 88.3 3.9 9.3e-13 47.5 0.0 3.6 2 2 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGG41389.1 - 0.00019 20.8 1.2 0.068 12.4 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Ribosomal_S30 PF04758.9 EGG41393.1 - 1.5e-07 31.0 6.3 3e-07 30.0 4.4 1.8 1 1 0 1 1 1 1 Ribosomal protein S30 Radical_SAM PF04055.16 EGG41394.1 - 4.5e-08 33.4 0.0 1.2e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily NAD_binding_1 PF00175.16 EGG41395.1 - 8.4e-15 55.2 0.1 1.7e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.4 EGG41395.1 - 1.5e-10 40.3 8.6 2.9e-10 39.4 5.9 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.19 EGG41395.1 - 2.6e-07 30.6 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGG41395.1 - 0.49 10.2 3.0 17 5.3 0.0 2.7 3 0 0 3 3 3 0 Ferric reductase NAD binding domain DHO_dh PF01180.16 EGG41396.1 - 3.1e-56 190.5 1.1 3.5e-56 190.3 0.8 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.12 EGG41396.1 - 5.2e-06 25.5 0.2 0.0028 16.5 0.1 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EGG41396.1 - 1.3e-05 24.5 0.4 0.031 13.5 0.0 2.7 3 0 0 3 3 3 2 Histidine biosynthesis protein DUF561 PF04481.7 EGG41396.1 - 0.00018 20.5 8.2 0.00038 19.4 0.0 3.6 3 1 0 4 4 4 1 Protein of unknown function (DUF561) NMO PF03060.10 EGG41396.1 - 0.0002 20.5 0.5 0.0073 15.4 0.0 2.1 1 1 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 EGG41396.1 - 0.003 16.6 3.3 0.33 9.9 0.5 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EGG41396.1 - 0.0089 14.9 0.4 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 EGG41396.1 - 0.039 13.2 2.0 0.59 9.3 0.0 2.8 3 1 1 4 4 4 0 PcrB family Antimicrobial_8 PF08103.6 EGG41396.1 - 0.065 13.1 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 Uperin family G3P_antiterm PF04309.7 EGG41396.1 - 0.066 12.2 1.1 2.9 6.9 0.0 2.5 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator NOSIC PF08060.8 EGG41397.1 - 1.6e-20 72.6 0.0 2.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain TBP PF00352.16 EGG41398.1 - 3.1e-24 84.1 0.0 3.4e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) SHOCT PF09851.4 EGG41399.1 - 1e-08 34.3 5.4 1.8e-08 33.5 3.7 1.4 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.7 EGG41399.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein G RNA_pol_A_CTD PF03118.10 EGG41399.1 - 0.19 11.1 6.5 0.045 13.1 1.6 2.1 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain SHOCT PF09851.4 EGG41400.1 - 0.0018 17.6 5.7 0.0018 17.6 3.9 2.1 2 0 0 2 2 2 1 Short C-terminal domain FlgD_ig PF13860.1 EGG41402.1 - 0.041 13.6 0.0 0.25 11.1 0.0 2.2 1 1 1 2 2 2 0 FlgD Ig-like domain TruB_N PF01509.13 EGG41403.1 - 2.8e-25 89.2 0.2 4.7e-15 56.0 0.0 3.2 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EGG41403.1 - 3.9e-20 71.3 0.1 6.6e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 PUA domain DKCLD PF08068.7 EGG41403.1 - 1.8e-12 47.0 0.0 3.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 DKCLD (NUC011) domain AAA_18 PF13238.1 EGG41404.1 - 6.8e-13 49.0 0.0 1.1e-12 48.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EGG41404.1 - 2.2e-11 44.0 0.0 3.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.1 EGG41404.1 - 5.1e-11 43.4 0.1 7.5e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EGG41404.1 - 2.8e-06 27.2 0.5 4.5e-05 23.3 0.3 2.1 1 1 0 1 1 1 1 Shikimate kinase ADK PF00406.17 EGG41404.1 - 1.5e-05 24.8 0.2 5.3e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Adenylate kinase AAA PF00004.24 EGG41404.1 - 5.1e-05 23.4 0.0 8.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGG41404.1 - 0.0002 21.2 0.1 0.00033 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGG41404.1 - 0.00036 20.4 0.1 0.0014 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGG41404.1 - 0.00048 20.1 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGG41404.1 - 0.0011 18.3 0.2 0.0033 16.6 0.1 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Rad17 PF03215.10 EGG41404.1 - 0.0011 17.8 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EGG41404.1 - 0.0041 17.2 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Nif11 PF07862.6 EGG41404.1 - 0.0054 16.6 1.3 0.056 13.3 0.0 2.6 3 0 0 3 3 2 1 Nitrogen fixation protein of unknown function AAA_22 PF13401.1 EGG41404.1 - 0.0056 16.8 0.0 0.014 15.5 0.0 1.7 1 1 0 2 2 2 1 AAA domain MobB PF03205.9 EGG41404.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EGG41404.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.7 EGG41404.1 - 0.02 13.9 0.1 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Guanylate_kin PF00625.16 EGG41404.1 - 0.021 14.2 0.4 0.96 8.8 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_19 PF13245.1 EGG41404.1 - 0.021 14.5 0.1 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 EGG41404.1 - 0.029 13.9 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGG41404.1 - 0.055 12.5 0.7 0.11 11.5 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin DUF3616 PF12275.3 EGG41404.1 - 0.056 12.4 0.1 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) AAA_16 PF13191.1 EGG41404.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EGG41404.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF106 PF01956.11 EGG41405.1 - 9.4e-15 54.5 13.7 4.5e-14 52.3 9.5 1.8 1 1 0 1 1 1 1 Integral membrane protein DUF106 DUF2207 PF09972.4 EGG41405.1 - 0.017 13.7 0.2 0.02 13.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2208 PF09973.4 EGG41405.1 - 0.96 8.6 8.8 0.038 13.2 2.1 1.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2208) PepSY_TM_2 PF13703.1 EGG41405.1 - 1.4 9.1 4.7 9.3 6.4 1.6 2.6 2 1 0 2 2 2 0 PepSY-associated TM helix AAA_18 PF13238.1 EGG41406.1 - 1.7e-12 47.7 0.0 3e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG41406.1 - 1.8e-06 28.7 0.0 3e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGG41406.1 - 4.5e-05 23.2 0.4 5.9e-05 22.8 0.3 1.5 1 1 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 EGG41406.1 - 4.9e-05 23.0 0.3 0.00011 21.8 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EGG41406.1 - 5.3e-05 22.5 0.1 7e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EGG41406.1 - 0.0001 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EGG41406.1 - 0.00015 21.3 0.2 0.00032 20.1 0.2 1.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EGG41406.1 - 0.00019 21.5 0.1 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EGG41406.1 - 0.00022 21.7 0.4 0.00037 20.9 0.1 1.6 2 0 0 2 2 1 1 Miro-like protein NACHT PF05729.7 EGG41406.1 - 0.0003 20.4 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGG41406.1 - 0.00031 20.8 0.1 0.00069 19.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EGG41406.1 - 0.00032 20.3 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGG41406.1 - 0.00034 20.8 0.1 0.00067 19.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGG41406.1 - 0.00042 20.2 0.0 0.00066 19.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGG41406.1 - 0.00049 20.4 1.2 0.00059 20.1 0.8 1.5 1 1 0 1 1 1 1 ABC transporter NTPase_1 PF03266.10 EGG41406.1 - 0.00055 19.6 2.6 0.0024 17.6 0.2 2.2 1 1 0 2 2 2 1 NTPase cobW PF02492.14 EGG41406.1 - 0.00083 18.8 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EGG41406.1 - 0.0009 19.1 0.8 0.0012 18.8 0.6 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EGG41406.1 - 0.0027 17.4 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ATP_bind_1 PF03029.12 EGG41406.1 - 0.0036 16.8 0.4 0.0085 15.6 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EGG41406.1 - 0.0043 16.2 0.5 0.0075 15.4 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EGG41406.1 - 0.0046 16.8 0.3 0.011 15.6 0.1 1.8 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGG41406.1 - 0.0063 15.7 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGG41406.1 - 0.011 15.4 0.1 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EGG41406.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EGG41406.1 - 0.013 14.6 0.1 0.025 13.6 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EGG41406.1 - 0.013 15.0 2.1 0.036 13.6 1.5 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGG41406.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ras PF00071.17 EGG41406.1 - 0.017 14.5 0.4 0.035 13.5 0.2 1.6 2 0 0 2 2 1 0 Ras family ArgK PF03308.11 EGG41406.1 - 0.017 13.8 0.2 0.031 13.0 0.1 1.3 1 0 0 1 1 1 0 ArgK protein PIF1 PF05970.9 EGG41406.1 - 0.046 12.6 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase SRPRB PF09439.5 EGG41406.1 - 0.051 12.8 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 EGG41406.1 - 0.058 12.7 0.3 0.15 11.4 0.2 2.1 1 1 0 1 1 1 0 Thymidylate kinase NB-ARC PF00931.17 EGG41406.1 - 0.069 11.9 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 EGG41406.1 - 0.088 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EGG41406.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SecY PF00344.15 EGG41407.1 - 1.5e-82 277.2 19.6 1.9e-82 276.9 13.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EGG41407.1 - 3.5e-11 42.3 0.6 1.1e-10 40.8 0.4 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p PSI_PsaJ PF01701.13 EGG41407.1 - 0.52 10.1 6.6 35 4.2 0.2 4.0 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Ribosomal_L18e PF00828.14 EGG41408.1 - 8e-23 81.2 0.1 1e-22 80.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L30 PF00327.15 EGG41409.1 - 1.3e-14 53.4 0.1 2.4e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5 PF00333.15 EGG41410.1 - 2e-19 69.1 0.4 3.2e-19 68.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGG41410.1 - 4.3e-15 54.7 0.1 9.4e-15 53.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF3628 PF12300.3 EGG41410.1 - 1.2 9.2 9.9 1.9 8.4 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Ribosomal_L18p PF00861.17 EGG41411.1 - 5.3e-21 75.0 1.6 7.8e-21 74.4 1.1 1.2 1 0 0 1 1 1 1 Ribosomal L18p/L5e family OTCace PF00185.19 EGG41412.1 - 2.9e-49 166.9 0.0 4.6e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EGG41412.1 - 5.7e-49 165.4 0.0 7.9e-49 164.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Sucrose_synth PF00862.14 EGG41412.1 - 0.022 12.7 0.0 0.031 12.2 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase CDC37_M PF08565.6 EGG41412.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain SRP54 PF00448.17 EGG41413.1 - 6.5e-70 234.5 0.6 9.2e-70 234.0 0.4 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EGG41413.1 - 3e-09 36.8 6.3 8.4e-09 35.4 4.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Trypan_PARP PF05887.6 EGG41413.1 - 3e-07 30.3 48.4 3e-07 30.3 33.5 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) AAA_30 PF13604.1 EGG41413.1 - 1.7e-06 27.7 0.1 3.2e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG41413.1 - 1.8e-05 24.8 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG41413.1 - 0.00027 20.0 0.2 0.00045 19.3 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.18 EGG41413.1 - 0.00034 20.0 0.2 0.00085 18.7 0.2 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 EGG41413.1 - 0.0005 19.5 0.5 0.0014 18.0 0.3 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGG41413.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGG41413.1 - 0.0014 18.3 0.2 0.0095 15.6 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EGG41413.1 - 0.0015 18.7 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGG41413.1 - 0.0032 17.1 0.1 0.0059 16.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGG41413.1 - 0.005 16.8 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EGG41413.1 - 0.015 14.9 0.1 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase PIF1 PF05970.9 EGG41413.1 - 0.017 14.1 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase DAP3 PF10236.4 EGG41413.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EGG41413.1 - 0.023 13.6 0.1 0.046 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TK PF00265.13 EGG41413.1 - 0.026 14.0 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Thymidine kinase ABC_tran PF00005.22 EGG41413.1 - 0.034 14.4 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 EGG41413.1 - 0.038 12.7 0.1 0.14 10.9 0.0 1.8 1 1 0 1 1 1 0 ArgK protein KTI12 PF08433.5 EGG41413.1 - 0.041 13.0 0.6 0.083 12.0 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PEPCK_ATP PF01293.15 EGG41413.1 - 0.042 12.3 0.1 0.068 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Thymidylate_kin PF02223.12 EGG41413.1 - 0.056 12.8 0.0 0.056 12.8 0.0 2.0 2 0 0 2 2 1 0 Thymidylate kinase B12-binding PF02310.14 EGG41413.1 - 0.065 13.1 0.3 0.15 11.9 0.2 1.6 1 1 0 1 1 1 0 B12 binding domain AAA_5 PF07728.9 EGG41413.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPP_enzyme_M PF00205.17 EGG41413.1 - 0.091 12.5 0.1 0.63 9.7 0.1 2.3 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Sigma70_ner PF04546.8 EGG41413.1 - 0.32 10.5 7.1 0.78 9.3 2.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Prefoldin PF02996.12 EGG41414.1 - 4.8e-16 58.4 8.9 2.3e-15 56.3 6.2 1.9 1 1 0 1 1 1 1 Prefoldin subunit LMP PF04778.7 EGG41414.1 - 0.00065 19.4 0.2 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 LMP repeated region TMF_TATA_bd PF12325.3 EGG41414.1 - 0.011 15.4 6.7 0.069 12.8 0.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NIT PF08376.5 EGG41414.1 - 0.021 14.3 4.4 0.093 12.2 0.3 2.0 1 1 1 2 2 2 0 Nitrate and nitrite sensing SF-assemblin PF06705.6 EGG41414.1 - 0.026 13.6 1.9 0.44 9.6 0.6 2.0 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF2408 PF10303.4 EGG41414.1 - 0.043 13.9 1.6 0.052 13.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Reo_sigmaC PF04582.7 EGG41414.1 - 0.2 10.8 2.1 0.34 10.0 0.2 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EGG41414.1 - 0.59 9.9 11.2 0.12 12.1 1.3 2.3 2 1 0 2 2 2 0 Prefoldin subunit ALIX_LYPXL_bnd PF13949.1 EGG41414.1 - 0.69 8.8 5.7 1.2 7.9 0.7 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Ax_dynein_light PF10211.4 EGG41414.1 - 0.95 9.2 6.8 4.9 6.9 0.2 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DUF948 PF06103.6 EGG41414.1 - 1.6 8.6 4.9 9.5 6.1 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 EGG41414.1 - 5.5 6.8 10.5 3.6 7.4 2.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.1 EGG41414.1 - 8.3 6.4 10.9 7.8 6.5 1.1 2.4 2 0 0 2 2 2 0 FlxA-like protein Sod_Fe_C PF02777.13 EGG41415.1 - 1.2e-43 147.3 0.3 2.1e-43 146.4 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGG41415.1 - 1.9e-29 101.7 1.5 3.5e-29 100.9 1.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_S8 PF00082.17 EGG41416.1 - 1.2e-61 208.3 0.7 1.8e-61 207.7 0.5 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EGG41416.1 - 6.6e-10 38.5 0.0 5.3e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 PA domain PEPCK_ATP PF01293.15 EGG41417.1 - 2.9e-218 725.0 0.0 3.3e-218 724.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ribosomal_L32e PF01655.13 EGG41419.1 - 6.4e-34 116.3 0.1 7.7e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L19e PF01280.15 EGG41420.1 - 1.3e-41 141.8 10.3 1.5e-41 141.6 7.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e Fe_hyd_SSU PF02256.12 EGG41420.1 - 0.0039 17.1 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit DNA_binding_1 PF01035.15 EGG41421.1 - 7.6e-30 102.5 0.0 8.7e-30 102.3 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain tRNA_deacylase PF04414.7 EGG41422.1 - 1e-58 197.9 0.0 1.3e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase SecE PF00584.15 EGG41423.1 - 0.00045 19.7 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Frag1 PF10277.4 EGG41423.1 - 0.027 13.9 0.0 0.028 13.8 0.0 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Spt5-NGN PF03439.8 EGG41424.1 - 4.4e-20 71.2 0.0 6.8e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EGG41424.1 - 3.1e-06 26.6 0.2 6.8e-06 25.5 0.2 1.6 1 0 0 1 1 1 1 KOW motif NusG PF02357.14 EGG41424.1 - 0.018 15.2 0.0 0.059 13.6 0.0 1.8 1 1 0 1 1 1 0 Transcription termination factor nusG Ribosomal_L11_N PF03946.9 EGG41425.1 - 2.2e-24 84.6 0.8 4.7e-24 83.6 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGG41425.1 - 4.7e-21 74.7 1.3 9.3e-21 73.7 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SBP_bac_5 PF00496.17 EGG41425.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Hom_end PF05204.9 EGG41425.1 - 0.089 12.7 0.3 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Homing endonuclease AsnC_trans_reg PF01037.16 EGG41426.1 - 6e-16 57.9 0.1 8.6e-16 57.4 0.1 1.2 1 0 0 1 1 1 1 AsnC family HTH_24 PF13412.1 EGG41426.1 - 7e-09 34.9 0.3 1.2e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EGG41426.1 - 9.5e-05 21.8 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain B-block_TFIIIC PF04182.7 EGG41426.1 - 0.00021 21.0 0.1 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Ribosomal_S25 PF03297.10 EGG41426.1 - 0.0022 18.0 3.0 0.004 17.1 0.3 2.2 2 1 1 3 3 3 1 S25 ribosomal protein MarR PF01047.17 EGG41426.1 - 0.0095 15.6 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 EGG41426.1 - 0.017 14.8 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 EGG41426.1 - 0.032 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 EGG41426.1 - 0.046 13.3 0.1 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 HTH domain HTH_psq PF05225.11 EGG41426.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DDRGK PF09756.4 EGG41426.1 - 0.11 11.8 1.1 5.1 6.4 0.0 2.1 2 0 0 2 2 2 0 DDRGK domain Ribosomal_L1 PF00687.16 EGG41427.1 - 8.1e-43 146.3 1.6 9.8e-43 146.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF1439 PF07273.7 EGG41427.1 - 0.064 12.9 0.5 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1439) Ribosomal_L10 PF00466.15 EGG41428.1 - 9.1e-18 64.0 0.5 9.1e-18 64.0 0.4 2.0 2 1 0 2 2 2 1 Ribosomal protein L10 UPF0126 PF03458.8 EGG41429.1 - 7e-39 131.3 25.1 2.1e-20 72.1 7.1 2.4 3 0 0 3 3 3 2 UPF0126 domain DUF4131 PF13567.1 EGG41429.1 - 3.4 7.0 6.2 13 5.1 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_60s PF00428.14 EGG41430.1 - 2.5e-11 43.8 15.8 2.9e-11 43.6 11.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 EGG41430.1 - 0.15 12.0 6.2 0.3 11.0 2.4 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF2636 PF11120.3 EGG41431.1 - 0.014 14.8 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Polysacc_synt_C PF14667.1 EGG41432.1 - 0.01 15.6 7.4 0.01 15.6 5.2 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF3040 PF11239.3 EGG41432.1 - 0.083 12.9 8.5 0.13 12.2 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Neurensin PF14927.1 EGG41432.1 - 0.21 10.9 6.5 0.32 10.3 4.1 1.6 1 1 0 1 1 1 0 Neurensin DUF981 PF06168.6 EGG41432.1 - 0.22 11.2 5.0 0.24 11.1 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF3188 PF11384.3 EGG41432.1 - 0.25 10.9 10.8 0.13 11.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF4199 PF13858.1 EGG41432.1 - 0.39 10.6 6.9 0.44 10.4 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4225 PF13988.1 EGG41432.1 - 0.46 9.9 5.8 0.51 9.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DUF2614 PF11023.3 EGG41432.1 - 0.84 9.4 4.0 1 9.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Claudin_2 PF13903.1 EGG41432.1 - 0.92 9.1 5.5 0.97 9.0 3.8 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IncA PF04156.9 EGG41432.1 - 1 8.9 16.8 1.1 8.7 11.6 1.1 1 0 0 1 1 1 0 IncA protein DUF308 PF03729.8 EGG41432.1 - 1.2 9.1 15.1 2.3 8.2 10.3 1.5 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) CRPA PF05745.6 EGG41432.1 - 1.4 8.7 6.8 1.7 8.4 4.7 1.2 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) PIRT PF15099.1 EGG41432.1 - 1.8 7.8 4.8 2 7.6 3.4 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family SdpI PF13630.1 EGG41432.1 - 2.9 7.6 10.7 3.9 7.2 7.4 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Pox_A14 PF05767.7 EGG41432.1 - 4 7.4 5.9 5.6 6.9 4.1 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF202 PF02656.10 EGG41432.1 - 9.3 6.5 8.2 15 5.8 5.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3240 PF11582.3 EGG41433.1 - 0.058 13.3 0.1 0.087 12.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) BESS PF02944.15 EGG41433.1 - 0.24 10.9 1.2 23 4.6 0.0 2.6 2 0 0 2 2 2 0 BESS motif DDE_Tnp_IS240 PF13610.1 EGG41434.1 - 5.1e-25 88.0 0.9 1e-23 83.8 0.1 2.2 2 0 0 2 2 2 1 DDE domain rve PF00665.21 EGG41434.1 - 5.9e-09 36.0 0.2 1.6e-08 34.6 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EGG41434.1 - 3.8e-06 26.3 1.5 4.8e-06 26.0 0.2 1.9 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS66 PF03050.9 EGG41434.1 - 2.2e-05 23.8 0.3 4.9e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Transposase IS66 family Transposase_mut PF00872.13 EGG41434.1 - 0.0002 20.0 0.9 0.09 11.3 0.0 2.2 2 0 0 2 2 2 2 Transposase, Mutator family SWIM PF04434.12 EGG41434.1 - 0.0025 17.2 2.5 0.0061 16.0 1.7 1.6 1 0 0 1 1 1 1 SWIM zinc finger Alpha-amylase_N PF02903.9 EGG41434.1 - 0.0028 17.6 0.3 0.0028 17.6 0.2 1.9 2 0 0 2 2 2 1 Alpha amylase, N-terminal ig-like domain Zn_Tnp_IS1 PF03811.8 EGG41434.1 - 0.016 14.6 2.2 0.06 12.8 1.5 2.0 1 0 0 1 1 1 0 InsA N-terminal domain DDE_Tnp_ISAZ013 PF07592.6 EGG41434.1 - 0.017 13.9 0.1 0.49 9.0 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_23 PF13384.1 EGG41434.1 - 0.023 14.3 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 EGG41434.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain zf-Dof PF02701.10 EGG41434.1 - 0.047 13.6 0.9 0.53 10.2 1.2 2.1 2 0 0 2 2 2 0 Dof domain, zinc finger Antitoxin-MazE PF04014.13 EGG41437.1 - 0.0039 16.8 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE DUF456 PF04306.8 EGG41438.1 - 0.023 14.7 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF1449 PF07290.6 EGG41438.1 - 0.024 13.9 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF1542 PF07564.6 EGG41438.1 - 0.057 13.4 1.9 0.085 12.8 1.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF4235 PF14019.1 EGG41438.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DUF4179 PF13786.1 EGG41438.1 - 0.13 12.4 0.5 0.16 12.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Methyltransf_11 PF08241.7 EGG41441.1 - 2.6e-08 34.2 0.0 4.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41441.1 - 8.9e-08 32.0 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41441.1 - 8.2e-07 29.4 0.0 1.8e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG41441.1 - 1e-06 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGG41441.1 - 2.8e-06 26.4 0.1 3.8e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.2 EGG41441.1 - 2e-05 25.1 0.0 5e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGG41441.1 - 9.5e-05 21.8 0.0 0.00048 19.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase small domain NodS PF05401.6 EGG41441.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) zf-CSL PF05207.8 EGG41441.1 - 0.0043 16.5 0.8 0.0086 15.5 0.5 1.5 1 0 0 1 1 1 1 CSL zinc finger Trm112p PF03966.11 EGG41441.1 - 0.013 15.8 0.2 0.11 12.8 0.1 2.6 2 1 0 2 2 2 0 Trm112p-like protein Methyltransf_26 PF13659.1 EGG41441.1 - 0.046 13.7 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TF_Zn_Ribbon PF08271.7 EGG41441.1 - 0.11 11.8 0.1 0.3 10.4 0.1 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding YHS PF04945.8 EGG41441.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 YHS domain DUF4325 PF14213.1 EGG41442.1 - 0.052 13.2 0.5 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) Aha1_N PF09229.6 EGG41442.1 - 0.074 12.8 0.4 0.085 12.6 0.3 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal Herpes_UL74 PF07982.7 EGG41443.1 - 0.0051 15.5 0.3 0.019 13.6 0.1 1.8 2 0 0 2 2 2 1 Herpes UL74 glycoproteins Transglut_core2 PF13369.1 EGG41444.1 - 1.3e-39 135.1 0.0 1.9e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.1 EGG41444.1 - 1.5e-14 53.5 0.0 2.5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG41444.1 - 0.00026 20.7 0.1 0.59 10.0 0.0 2.7 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 EGG41444.1 - 0.00053 19.4 0.1 1.2 8.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG41444.1 - 0.032 13.8 0.1 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 TPR repeat YfzA PF14118.1 EGG41444.1 - 0.095 12.8 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 YfzA-like protein TPR_2 PF07719.12 EGG41444.1 - 0.11 12.4 0.0 25 5.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DivIC PF04977.10 EGG41445.1 - 0.0031 16.9 1.4 0.0043 16.4 1.0 1.4 1 1 0 1 1 1 1 Septum formation initiator HCR PF07111.7 EGG41445.1 - 0.061 11.3 0.1 0.066 11.2 0.1 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF904 PF06005.7 EGG41445.1 - 0.088 13.1 0.4 0.096 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF1192 PF06698.6 EGG41445.1 - 0.095 12.5 2.8 0.28 11.0 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) TSC22 PF01166.13 EGG41445.1 - 0.095 12.6 0.7 0.16 11.9 0.5 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EGG41445.1 - 0.12 12.1 0.9 0.23 11.3 0.1 1.7 1 1 1 2 2 2 0 Basic region leucine zipper OrfB_Zn_ribbon PF07282.6 EGG41446.1 - 0.0079 15.8 0.3 0.0085 15.7 0.2 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.7 EGG41446.1 - 0.013 15.3 1.0 0.65 9.8 0.1 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_4 PF14570.1 EGG41446.1 - 0.057 13.0 3.6 3.5 7.2 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 EGG41446.1 - 0.09 12.3 0.4 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF4451 PF14616.1 EGG41446.1 - 0.11 12.2 2.1 0.57 9.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) IBR PF01485.16 EGG41446.1 - 0.12 12.2 1.0 0.2 11.5 0.7 1.4 1 1 0 1 1 1 0 IBR domain zf-DBF PF07535.7 EGG41446.1 - 0.3 10.7 1.7 0.51 10.0 0.4 1.8 2 0 0 2 2 2 0 DBF zinc finger zf-Apc11 PF12861.2 EGG41446.1 - 0.41 10.4 1.8 15 5.5 0.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EGG41446.1 - 0.51 10.1 2.4 3.3 7.4 0.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.5 EGG41446.1 - 1.3 9.0 3.7 9.8 6.2 1.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain YusW PF14039.1 EGG41448.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 YusW-like protein DUF2147 PF09917.4 EGG41448.1 - 0.011 15.9 0.1 0.021 15.1 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) PD40 PF07676.7 EGG41449.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat zf-C3HC4_3 PF13920.1 EGG41450.1 - 0.066 12.8 10.1 0.35 10.5 5.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.11 EGG41450.1 - 8.2 6.1 8.5 5.4 6.7 1.8 2.3 2 0 0 2 2 2 0 HIT zinc finger HATPase_c PF02518.21 EGG41451.1 - 5.8e-21 74.2 0.1 1.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG41451.1 - 2e-12 46.9 0.1 5.1e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG41451.1 - 9.7e-08 31.6 2.6 2.4e-07 30.3 0.0 2.9 3 0 0 3 3 3 1 GHKL domain HAMP PF00672.20 EGG41451.1 - 2.8e-07 30.6 0.0 1.4e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 HAMP domain Response_reg PF00072.19 EGG41452.1 - 9.5e-22 77.1 0.7 1.1e-21 76.9 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain SHOCT PF09851.4 EGG41455.1 - 0.14 11.6 0.4 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 Short C-terminal domain A2M_N PF01835.14 EGG41455.1 - 0.83 9.9 3.9 0.38 11.0 0.1 2.3 2 1 1 3 3 3 0 MG2 domain Metallophos_2 PF12850.2 EGG41459.1 - 3.1e-21 75.8 0.1 4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGG41459.1 - 3.1e-17 62.6 0.3 4.3e-17 62.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EGG41459.1 - 9.4e-05 21.6 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily DUF2124 PF09897.4 EGG41459.1 - 0.0025 17.4 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) Iso_dh PF00180.15 EGG41460.1 - 1.9e-81 273.7 0.6 2.3e-81 273.4 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_31 PF13847.1 EGG41461.1 - 4.1e-09 36.1 0.6 1.8e-08 34.1 0.4 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41461.1 - 1.5e-08 34.5 0.0 1e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG41461.1 - 1.4e-07 31.0 0.0 2.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGG41461.1 - 2.7e-06 27.7 0.1 1e-05 25.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG41461.1 - 1.2e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41461.1 - 4.9e-05 23.7 0.2 0.00015 22.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41461.1 - 0.00014 22.3 0.0 0.00072 20.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG41461.1 - 0.00034 20.2 0.0 0.0009 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EGG41461.1 - 0.0019 17.3 0.1 0.0026 16.9 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EGG41461.1 - 0.0034 16.4 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 EGG41461.1 - 0.005 17.1 0.1 0.054 13.8 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGG41461.1 - 0.005 16.5 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGG41461.1 - 0.048 12.7 0.1 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EGG41462.1 - 5.8e-39 133.6 0.4 6.7e-39 133.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 EGG41462.1 - 1.1e-06 28.3 2.6 0.00051 19.6 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain PCMT PF01135.14 EGG41462.1 - 6.8e-05 22.5 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGG41462.1 - 0.00026 21.5 0.0 0.0004 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG41462.1 - 0.00057 19.8 0.0 0.00078 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41462.1 - 0.0083 15.8 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGG41462.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGG41462.1 - 0.025 15.0 0.0 0.093 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGG41462.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGG41462.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF655 PF04919.7 EGG41463.1 - 4e-51 173.2 0.2 4.6e-51 173.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.1 EGG41463.1 - 7.2e-05 22.7 0.0 0.00023 21.1 0.0 1.7 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.2 EGG41463.1 - 0.0021 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RNA_pol_Rpb4 PF03874.11 EGG41464.1 - 4e-14 52.6 0.8 8.7e-14 51.5 0.6 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Ribosomal_L21e PF01157.13 EGG41465.1 - 5.4e-14 51.8 1.6 7.3e-14 51.3 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Radical_SAM PF04055.16 EGG41466.1 - 3.9e-14 53.1 0.0 8e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EGG41466.1 - 2e-05 24.5 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EGG41466.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain Rad51 PF08423.6 EGG41467.1 - 4.6e-67 225.6 0.0 5.6e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGG41467.1 - 2.6e-07 30.2 0.1 4.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EGG41467.1 - 0.0017 17.4 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein NARP1 PF12569.3 EGG41467.1 - 0.2 10.4 8.5 0.28 9.8 5.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_L35p PF01632.14 EGG41467.1 - 1.5 8.7 7.4 5.2 7.0 0.1 3.1 2 1 1 3 3 3 0 Ribosomal protein L35 tRNA_int_endo PF01974.12 EGG41468.1 - 1.8e-18 66.1 0.1 4.1e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGG41468.1 - 8.7e-12 44.4 4.3 2.6e-11 42.8 0.5 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Ribosomal_L16 PF00252.13 EGG41469.1 - 3.3e-22 78.6 0.4 4.1e-22 78.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1492 PF07374.6 EGG41470.1 - 0.073 13.1 1.3 0.073 13.1 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) Na_H_Exchanger PF00999.16 EGG41472.1 - 2.1e-57 194.3 56.6 2.9e-57 193.9 39.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HSBP1 PF06825.7 EGG41474.1 - 4.6e-06 26.1 4.5 0.16 11.5 0.0 5.3 3 1 1 4 4 4 2 Heat shock factor binding protein 1 NPV_P10 PF05531.7 EGG41474.1 - 1.8e-05 24.8 38.9 0.27 11.5 1.7 6.5 2 2 4 7 7 7 4 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EGG41474.1 - 0.00079 19.2 38.6 0.0026 17.5 1.2 5.6 1 1 5 6 6 6 2 Protein of unknown function (DUF1664) PilJ PF13675.1 EGG41474.1 - 0.00084 19.6 3.1 0.17 12.2 0.3 4.2 1 1 4 5 5 5 1 Type IV pili methyl-accepting chemotaxis transducer N-term MCPsignal PF00015.16 EGG41474.1 - 0.0041 16.7 40.0 0.29 10.6 7.7 4.0 1 1 2 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.5 EGG41474.1 - 0.0041 17.2 2.2 0.0041 17.2 1.5 4.9 1 1 5 6 6 6 1 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.1 EGG41474.1 - 0.035 14.1 43.3 0.029 14.4 2.1 5.9 1 1 5 6 6 6 0 Syntaxin-like protein Serine_rich PF08824.5 EGG41474.1 - 0.074 12.7 14.5 5.2 6.7 1.1 4.4 1 1 3 5 5 5 0 Serine rich protein interaction domain AAA_13 PF13166.1 EGG41474.1 - 0.075 11.4 43.6 0.0052 15.3 9.2 2.9 1 1 2 3 3 3 0 AAA domain DUF948 PF06103.6 EGG41474.1 - 0.086 12.7 36.7 1.2 9.0 1.6 6.5 1 1 6 7 7 7 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EGG41474.1 - 0.16 11.5 24.8 0.094 12.3 4.0 3.7 1 1 3 4 4 4 0 IncA protein DASH_Dad4 PF08650.5 EGG41474.1 - 0.17 11.8 10.8 2.4 8.1 0.2 4.0 3 1 0 3 3 3 0 DASH complex subunit Dad4 Cauli_AT PF03233.8 EGG41474.1 - 0.33 10.6 39.0 0.38 10.4 0.2 5.1 2 2 3 5 5 5 0 Aphid transmission protein FlaC_arch PF05377.6 EGG41474.1 - 0.36 10.7 29.6 1.5 8.7 0.2 7.5 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) MitMem_reg PF13012.1 EGG41474.1 - 0.53 10.3 31.9 0.73 9.9 1.2 5.3 1 1 4 5 5 5 0 Maintenance of mitochondrial structure and function DUF869 PF05911.6 EGG41474.1 - 0.9 7.6 41.9 1.4 7.0 27.8 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EGG41474.1 - 0.95 8.5 32.7 0.44 9.6 0.8 4.2 1 1 3 4 4 4 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EGG41474.1 - 1.4 9.1 47.5 0.46 10.6 1.8 6.9 1 1 5 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EGG41474.1 - 2 8.1 42.6 0.097 12.4 6.0 4.9 1 1 2 4 4 4 0 Laminin Domain II CENP-F_leu_zip PF10473.4 EGG41474.1 - 2.2 8.1 36.0 0.41 10.4 6.8 4.2 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.20 EGG41474.1 - 7.4 6.7 48.0 0.91 9.7 3.5 6.1 2 1 3 5 5 5 0 Syntaxin Syntaxin-6_N PF09177.6 EGG41474.1 - 8.2 6.9 28.2 0.98 9.8 2.4 5.3 2 2 2 5 5 5 0 Syntaxin 6, N-terminal Glyco_tranf_2_3 PF13641.1 EGG41475.1 - 5.5e-33 114.6 0.0 8e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGG41475.1 - 4.2e-20 72.2 0.4 8e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EGG41475.1 - 8.3e-16 58.1 0.0 1.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGG41475.1 - 8.5e-12 44.6 0.1 1.5e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Fer4 PF00037.22 EGG41476.1 - 4.5e-08 32.3 16.0 0.00014 21.3 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EGG41476.1 - 1.1e-06 28.7 5.1 2.3e-06 27.7 3.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGG41476.1 - 2.9e-06 27.5 5.1 6e-06 26.5 3.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGG41476.1 - 3.2e-06 26.8 5.2 6.6e-06 25.8 3.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGG41476.1 - 6.5e-05 22.6 3.3 0.0001 22.0 2.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGG41476.1 - 0.00022 20.9 13.1 0.0036 17.1 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EGG41476.1 - 0.0018 18.2 4.1 0.012 15.6 3.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGG41476.1 - 0.0033 17.8 3.6 0.62 10.5 0.4 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EGG41476.1 - 0.0042 17.4 0.6 3.4 8.0 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGG41476.1 - 0.008 16.0 11.0 0.077 12.9 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EGG41476.1 - 0.047 14.0 5.0 3.8 8.0 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.2 EGG41476.1 - 0.12 12.9 15.1 0.22 12.1 1.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.1 EGG41476.1 - 0.43 11.0 8.1 0.64 10.4 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGG41476.1 - 0.54 10.8 10.7 0.45 11.1 0.4 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 EGG41476.1 - 0.72 10.6 7.6 5.4 7.8 1.5 2.5 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Rhodanese PF00581.15 EGG41478.1 - 1.8e-38 131.3 0.3 2.5e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NAD_kinase PF01513.16 EGG41479.1 - 1.1e-36 126.1 1.7 1.3e-36 125.8 1.2 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EGG41479.1 - 0.00074 18.9 0.3 0.0027 17.1 0.0 1.9 2 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain CoA_binding_2 PF13380.1 EGG41479.1 - 0.0022 18.1 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain DZR PF12773.2 EGG41480.1 - 0.0043 16.8 1.2 0.0077 16.0 0.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon UPF0278 PF08745.6 EGG41480.1 - 0.017 14.3 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 UPF0278 family zf-ribbon_3 PF13248.1 EGG41480.1 - 0.018 14.2 4.7 0.033 13.3 3.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EGG41480.1 - 0.039 13.7 0.1 0.075 12.8 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbons DNA_ligase_ZBD PF03119.11 EGG41480.1 - 0.039 13.6 2.6 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1g PF09334.6 EGG41480.1 - 0.068 11.8 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-TFIIB PF13453.1 EGG41480.1 - 0.085 12.0 1.9 3.8 6.8 0.1 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C3HC4_3 PF13920.1 EGG41480.1 - 0.095 12.3 1.5 0.15 11.7 1.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3279 PF11682.3 EGG41480.1 - 0.12 11.9 0.5 0.19 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) PIN PF01850.16 EGG41480.1 - 0.12 12.6 0.1 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 PIN domain RecR PF02132.10 EGG41480.1 - 0.16 11.3 0.6 0.51 9.8 0.2 2.0 2 1 0 2 2 2 0 RecR protein Nudix_N_2 PF14803.1 EGG41480.1 - 0.27 10.9 4.0 0.8 9.4 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.6 EGG41480.1 - 0.38 10.4 2.0 1.1 9.0 1.4 1.9 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 EGG41480.1 - 1.5 8.4 6.5 30 4.2 4.5 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Rad50_zn_hook PF04423.9 EGG41480.1 - 2 7.9 4.8 1.3 8.5 0.2 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif Auto_anti-p27 PF06677.7 EGG41480.1 - 4.6 7.0 7.6 0.25 11.1 0.5 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2752 PF10825.3 EGG41480.1 - 8.1 6.5 8.5 2.9 7.9 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2752) Rhodanese PF00581.15 EGG41481.1 - 1.1e-32 112.7 0.0 1.8e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain ERCC4 PF02732.10 EGG41482.1 - 2.2e-18 66.3 0.0 4.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH PF00633.18 EGG41482.1 - 8.8e-08 31.4 0.0 0.0032 17.0 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EGG41482.1 - 1.9e-07 31.1 0.0 4.7e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EGG41482.1 - 8.7e-06 25.5 0.0 2.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.2 EGG41482.1 - 0.00017 21.4 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.1 EGG41482.1 - 0.0072 16.4 0.2 0.92 9.7 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain 5_3_exonuc PF01367.15 EGG41482.1 - 0.046 13.9 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF3701 PF12482.3 EGG41482.1 - 0.16 11.6 0.0 0.5 10.1 0.0 1.8 1 1 1 2 2 2 0 Phage integrase protein Prefoldin_2 PF01920.15 EGG41483.1 - 2.2e-22 78.8 19.3 2.5e-22 78.6 13.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit FixO PF02433.10 EGG41483.1 - 0.55 9.5 4.0 0.7 9.2 2.8 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Sld5 PF05916.6 EGG41483.1 - 1.5 9.1 6.0 3.1 8.1 4.2 1.7 1 1 0 1 1 1 0 GINS complex protein DUF342 PF03961.8 EGG41483.1 - 3.6 5.9 10.9 5 5.4 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Macoilin PF09726.4 EGG41483.1 - 5.2 5.2 11.5 6.2 4.9 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Nup88 PF10168.4 EGG41483.1 - 8 4.1 10.2 11 3.7 7.1 1.2 1 0 0 1 1 1 0 Nuclear pore component TP53IP5 PF15331.1 EGG41483.1 - 9.3 6.0 10.5 50 3.6 7.3 1.9 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Pcc1 PF09341.5 EGG41484.1 - 5.6e-06 26.3 0.0 6.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 TrkA_C PF02080.16 EGG41484.1 - 0.03 13.9 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 TrkA-C domain Ribosomal_L37ae PF01780.14 EGG41485.1 - 2.5e-19 68.9 1.8 2.7e-19 68.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGG41485.1 - 0.00083 19.1 3.1 0.00083 19.1 2.1 1.8 2 0 0 2 2 2 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGG41485.1 - 0.0038 16.8 2.6 0.0053 16.3 1.8 1.5 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EGG41485.1 - 0.016 15.1 1.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.17 EGG41485.1 - 0.019 14.7 2.7 0.024 14.3 1.8 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EGG41485.1 - 0.034 13.9 2.3 0.055 13.3 1.6 1.4 1 1 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EGG41485.1 - 0.042 13.9 1.3 0.061 13.4 0.9 1.3 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase GCC2_GCC3 PF07699.8 EGG41485.1 - 0.046 13.2 0.9 0.064 12.8 0.6 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 A2L_zn_ribbon PF08792.5 EGG41485.1 - 0.069 12.6 2.9 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ISL3 PF14690.1 EGG41485.1 - 0.076 13.0 0.8 0.56 10.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 EGG41485.1 - 0.12 11.6 2.1 0.22 10.8 1.5 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding Prok-RING_1 PF14446.1 EGG41485.1 - 0.16 11.7 1.1 0.3 10.8 0.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 EGG41485.1 - 0.17 11.1 4.2 1.3 8.3 3.0 2.0 1 1 1 2 2 2 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 EGG41485.1 - 0.29 10.8 1.8 0.51 10.0 1.2 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain UPF0547 PF10571.4 EGG41485.1 - 0.34 10.6 3.2 0.83 9.4 0.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 YdjO PF14169.1 EGG41485.1 - 0.41 10.1 2.4 5.1 6.6 0.1 2.1 1 1 1 2 2 2 0 Cold-inducible protein YdjO DUF1451 PF07295.6 EGG41485.1 - 0.44 10.3 3.0 0.45 10.2 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF2082 PF09855.4 EGG41485.1 - 0.61 9.9 3.7 1.4 8.8 0.1 2.3 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-RanBP PF00641.13 EGG41485.1 - 4 6.6 6.3 1.5 7.9 0.6 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RNase_PH PF01138.16 EGG41486.1 - 1.2e-20 74.1 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGG41486.1 - 1.1e-13 50.9 1.3 2.2e-13 49.9 0.0 2.2 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 SBBP PF06739.6 EGG41486.1 - 8.2 6.3 11.3 7 6.5 0.7 3.2 3 0 0 3 3 3 0 Beta-propeller repeat RNase_PH PF01138.16 EGG41487.1 - 1.2e-34 119.4 0.0 1.6e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGG41487.1 - 9.3e-13 47.9 0.1 2.2e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.24 EGG41488.1 - 1.4e-11 43.8 0.3 3.4e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EGG41488.1 - 3.3e-05 23.4 0.1 8.8e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 EGG41488.1 - 0.001 18.6 0.1 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EGG41488.1 - 0.058 13.0 0.1 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 KH domain TAF PF02969.12 EGG41488.1 - 0.1 12.5 0.3 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) SBDS PF01172.13 EGG41489.1 - 3.2e-26 90.9 0.1 5.4e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EGG41489.1 - 5.6e-21 74.5 0.1 9.3e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain Transp_Tc5_C PF04236.10 EGG41490.1 - 0.21 11.8 1.9 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DNA_RNApol_7kD PF03604.8 EGG41491.1 - 0.054 12.9 4.3 0.44 10.0 0.5 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Spore-coat_CotZ PF10612.4 EGG41492.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Spore coat protein Z zf-C4pol PF14260.1 EGG41495.1 - 0.019 14.9 0.7 0.024 14.6 0.5 1.2 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta LIM PF00412.17 EGG41495.1 - 0.037 14.0 0.1 0.043 13.8 0.1 1.1 1 0 0 1 1 1 0 LIM domain eIF-5_eIF-2B PF01873.12 EGG41495.1 - 0.14 11.8 0.6 0.16 11.6 0.4 1.1 1 0 0 1 1 1 0 Domain found in IF2B/IF5 RNA_pol_A_bac PF01000.21 EGG41497.1 - 6.2e-25 87.5 0.0 1.2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGG41497.1 - 6.9e-13 47.5 0.0 8.3e-13 47.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L18e PF00828.14 EGG41498.1 - 3.7e-09 37.0 0.1 4.8e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L13 PF00572.13 EGG41499.1 - 3e-26 91.9 0.0 3.6e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EGG41500.1 - 7.9e-36 122.9 0.2 9.1e-36 122.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NTP_transferase PF00483.18 EGG41501.1 - 5.3e-16 58.6 0.0 6.4e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGG41501.1 - 1.6e-10 41.2 0.0 1.8e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Aconitase_C PF00694.14 EGG41502.1 - 8.1e-41 139.1 0.0 1.4e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EGG41502.1 - 0.00014 21.3 0.1 0.0049 16.2 0.1 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase PF00330.15 EGG41503.1 - 3.5e-166 553.2 0.1 4e-166 553.1 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGG41504.1 - 3.9e-21 75.5 0.4 1.4e-19 70.4 0.0 2.3 2 1 1 3 3 3 2 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EGG41504.1 - 0.0019 17.6 0.2 0.012 15.0 0.1 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus DUF2683 PF10884.3 EGG41504.1 - 0.1 12.5 0.6 0.25 11.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Aconitase PF00330.15 EGG41505.1 - 4.9e-73 246.1 4.1 8.6e-48 162.9 0.5 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) ComX PF05952.7 EGG41506.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacillus competence pheromone ComX SIMPL PF04402.9 EGG41507.1 - 3.4e-45 154.5 3.9 4.3e-45 154.1 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF1082 PF06449.6 EGG41508.1 - 0.14 12.0 0.3 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) MFS_1 PF07690.11 EGG41509.1 - 1.8e-48 165.0 73.5 3.1e-44 151.1 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG41509.1 - 5e-12 45.1 8.2 5e-12 45.1 5.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGG41509.1 - 0.00046 18.5 12.5 0.00046 18.5 8.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1523 PF07509.6 EGG41509.1 - 0.081 12.1 0.2 0.081 12.1 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1523) MFS_2 PF13347.1 EGG41509.1 - 0.11 10.8 40.1 0.0091 14.4 4.0 3.7 1 1 1 3 3 3 0 MFS/sugar transport protein Adenylsucc_synt PF00709.16 EGG41510.1 - 0.0049 15.5 0.5 0.0054 15.4 0.4 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Mer2 PF09074.5 EGG41510.1 - 0.027 14.4 1.4 0.03 14.2 1.0 1.0 1 0 0 1 1 1 0 Mer2 ATP-synt_B PF00430.13 EGG41510.1 - 0.061 13.1 1.9 0.064 13.0 1.3 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Phage_terminase PF10668.4 EGG41510.1 - 0.07 12.9 1.8 0.09 12.5 1.2 1.3 1 0 0 1 1 1 0 Phage terminase small subunit DegS PF05384.6 EGG41510.1 - 0.075 12.2 1.5 0.14 11.4 1.1 1.4 1 1 0 1 1 1 0 Sensor protein DegS Sec5 PF15469.1 EGG41510.1 - 0.086 12.5 1.9 0.1 12.3 1.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 Flu_NS2 PF00601.14 EGG41510.1 - 0.099 12.8 1.4 0.14 12.4 1.0 1.2 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) FlaC_arch PF05377.6 EGG41510.1 - 0.18 11.7 4.9 1.6 8.6 0.8 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 EGG41510.1 - 0.56 10.2 4.7 0.73 9.8 3.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Iron_permease PF04120.7 EGG41511.1 - 0.019 14.5 0.4 0.019 14.5 0.3 1.0 1 0 0 1 1 1 0 Low affinity iron permease HHH_2 PF12826.2 EGG41511.1 - 0.024 14.5 0.3 0.17 11.7 0.0 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix motif FliG_M PF14841.1 EGG41511.1 - 0.087 12.8 0.1 0.09 12.7 0.1 1.1 1 0 0 1 1 1 0 FliG middle domain DUF2116 PF09889.4 EGG41512.1 - 0.0077 16.0 1.2 0.0081 15.9 0.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2256 PF10013.4 EGG41512.1 - 0.064 13.0 3.0 4.2 7.2 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3Hc3H PF13891.1 EGG41512.1 - 0.078 13.0 0.8 0.086 12.9 0.5 1.1 1 0 0 1 1 1 0 Potential DNA-binding domain zf-MYND PF01753.13 EGG41512.1 - 0.12 12.2 2.9 0.15 11.9 2.0 1.3 1 1 0 1 1 1 0 MYND finger Ribosomal_S14 PF00253.16 EGG41512.1 - 0.15 11.4 1.5 0.18 11.1 1.1 1.3 1 1 0 1 1 1 0 Ribosomal protein S14p/S29e NinF PF05810.7 EGG41512.1 - 0.17 11.7 0.5 0.19 11.5 0.4 1.0 1 0 0 1 1 1 0 NinF protein zf-HIT PF04438.11 EGG41512.1 - 5 6.8 6.9 78 3.0 4.8 2.0 1 1 0 1 1 1 0 HIT zinc finger GBP_C PF02841.9 EGG41514.1 - 0.009 15.2 6.4 0.016 14.4 4.5 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain GvpK PF05121.7 EGG41514.1 - 0.18 11.6 2.4 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 Gas vesicle protein K IncA PF04156.9 EGG41514.1 - 0.4 10.2 3.7 0.71 9.4 2.5 1.4 1 0 0 1 1 1 0 IncA protein HATPase_c PF02518.21 EGG41515.1 - 2.7e-24 85.0 0.1 4.6e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG41515.1 - 7e-11 41.9 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG41515.1 - 1.7e-07 30.8 1.3 4.6e-07 29.4 0.2 2.2 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 EGG41515.1 - 0.00048 19.7 0.1 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG41515.1 - 0.045 13.5 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain bPH_5 PF10882.3 EGG41515.1 - 0.07 12.9 1.4 0.38 10.5 0.1 2.7 2 2 0 2 2 2 0 Bacterial PH domain HATPase_c PF02518.21 EGG41516.1 - 5.9e-21 74.2 1.1 1.4e-20 73.0 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG41516.1 - 7.3e-09 35.4 0.0 1.9e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG41516.1 - 0.00018 21.1 0.4 0.00018 21.1 0.2 2.8 2 2 1 3 3 3 1 GHKL domain HATPase_c_3 PF13589.1 EGG41516.1 - 0.00027 20.6 0.1 0.00027 20.6 0.0 2.4 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG41516.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DDE_Tnp_IS66 PF03050.9 EGG41516.1 - 0.34 10.0 3.8 2.6 7.2 1.6 2.2 2 0 0 2 2 2 0 Transposase IS66 family DUF2252 PF10009.4 EGG41516.1 - 0.65 8.8 3.3 1 8.2 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) F420_ligase PF01996.11 EGG41517.1 - 8.3e-21 74.0 0.3 8.9e-21 74.0 0.2 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase SelB-wing_2 PF09106.6 EGG41517.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix F420_ligase PF01996.11 EGG41518.1 - 2.9e-15 55.9 0.0 3.4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase NDUF_B6 PF09782.4 EGG41519.1 - 0.015 15.1 2.0 0.023 14.5 1.4 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF684 PF05075.9 EGG41519.1 - 0.043 12.4 0.2 0.063 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF684) DUF473 PF04322.7 EGG41519.1 - 0.046 13.3 0.2 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF473) DUF2854 PF11016.3 EGG41522.1 - 0.085 12.3 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) P53_tetramer PF07710.6 EGG41522.1 - 0.32 10.1 2.0 0.41 9.7 0.2 2.0 2 0 0 2 2 2 0 P53 tetramerisation motif TPP_enzyme_C PF02775.16 EGG41523.1 - 5.9e-29 100.6 0.2 9.7e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.3 EGG41523.1 - 4.4e-08 32.9 0.1 0.00057 19.7 0.0 2.7 2 1 0 2 2 2 2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.14 EGG41524.1 - 1.3e-55 188.3 0.0 1.9e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 EGG41524.1 - 1.4e-26 93.4 0.0 3e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EGG41524.1 - 9.8e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.13 EGG41524.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain zf-ribbon_3 PF13248.1 EGG41525.1 - 0.0022 17.1 1.6 0.33 10.2 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGG41525.1 - 0.15 11.5 10.6 0.39 10.2 7.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGG41525.1 - 0.24 10.7 12.5 1.1 8.6 1.4 2.3 2 1 0 2 2 2 0 TFIIB zinc-binding DUF2387 PF09526.5 EGG41525.1 - 1.8 8.5 9.6 6.4 6.7 0.5 2.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) 2-Hacid_dh_C PF02826.14 EGG41526.1 - 5.3e-61 204.8 0.1 8.1e-61 204.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGG41526.1 - 2.8e-32 110.9 0.0 3.2e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGG41526.1 - 1.4e-06 28.2 0.2 2.3e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGG41526.1 - 1.6e-06 27.5 0.6 3.1e-06 26.6 0.1 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EGG41526.1 - 0.0007 19.9 0.1 0.0029 18.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 EGG41526.1 - 0.017 13.9 0.7 0.027 13.3 0.5 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase TrkA_N PF02254.13 EGG41526.1 - 0.024 14.6 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain AdoHcyase_NAD PF00670.16 EGG41526.1 - 0.047 13.5 0.2 0.083 12.7 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ChuX_HutX PF06228.8 EGG41527.1 - 2.7e-07 30.0 0.0 3.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX HemS PF05171.7 EGG41527.1 - 3.7e-06 26.7 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Haemin-degrading HemS.ChuX domain Apc9 PF12856.2 EGG41528.1 - 0.094 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 MFS_1 PF07690.11 EGG41529.1 - 3.2e-08 32.6 22.1 4.3e-08 32.2 15.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EGG41529.1 - 3.4 5.6 13.8 0.18 9.9 3.2 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector Pyr_redox_2 PF07992.9 EGG41530.1 - 1.2e-14 54.6 0.3 2.3e-13 50.5 0.2 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG41530.1 - 5.6e-13 49.1 0.2 2.2e-12 47.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG41530.1 - 0.0017 17.2 0.1 4.8 5.9 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGG41530.1 - 0.0019 18.3 0.0 0.0097 15.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2356 PF10189.4 EGG41530.1 - 0.035 13.1 0.6 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Conserved protein (DUF2356) ACT_7 PF13840.1 EGG41531.1 - 1.4e-07 30.9 0.1 2.6e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain SecD-TM1 PF13721.1 EGG41531.1 - 0.028 14.6 0.2 0.079 13.2 0.0 1.8 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Pox_A3L PF05288.6 EGG41531.1 - 0.15 11.7 0.6 0.6 9.8 0.0 2.3 3 1 0 3 3 3 0 Poxvirus A3L Protein HSP20 PF00011.16 EGG41532.1 - 6.6e-07 29.1 4.4 9e-06 25.4 3.1 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family AAA PF00004.24 EGG41533.1 - 3.6e-100 331.3 0.0 6.5e-51 171.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGG41533.1 - 2.2e-22 78.8 0.0 6e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EGG41533.1 - 2.6e-16 59.9 0.1 3.4e-07 30.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGG41533.1 - 3.2e-14 52.5 0.0 1.3e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGG41533.1 - 4.3e-13 50.1 0.0 4.4e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGG41533.1 - 4.3e-13 49.6 0.0 1.8e-06 28.1 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.9 EGG41533.1 - 1e-12 47.9 1.4 0.00015 21.5 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGG41533.1 - 2.2e-12 47.2 1.5 0.0021 18.2 0.2 4.5 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EGG41533.1 - 3.5e-11 43.1 0.0 5.5e-05 23.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EGG41533.1 - 5.9e-11 41.8 0.0 0.00014 21.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EGG41533.1 - 3.1e-10 39.3 0.1 0.00053 18.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 EGG41533.1 - 7.6e-10 38.8 0.0 0.00019 21.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EGG41533.1 - 9.6e-10 37.9 0.7 2.6e-09 36.5 0.5 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.12 EGG41533.1 - 2.9e-09 36.5 0.1 0.0019 17.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGG41533.1 - 1.2e-08 34.3 0.3 0.0016 17.6 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGG41533.1 - 2e-08 33.8 2.0 0.0065 16.1 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EGG41533.1 - 2.3e-08 34.4 0.8 0.0021 18.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EGG41533.1 - 3e-07 30.0 5.8 0.12 11.7 0.2 4.2 2 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGG41533.1 - 9.1e-07 28.4 0.3 0.17 11.3 0.0 4.1 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EGG41533.1 - 1e-06 28.8 0.1 0.058 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGG41533.1 - 1.2e-06 28.6 0.0 0.056 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EGG41533.1 - 5.6e-06 26.6 0.1 0.17 12.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.6 EGG41533.1 - 8.3e-06 25.4 0.0 0.025 14.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGG41533.1 - 1.4e-05 25.1 0.0 0.42 10.6 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_24 PF13479.1 EGG41533.1 - 2e-05 24.2 0.3 0.019 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGG41533.1 - 2e-05 24.2 0.8 0.46 10.1 0.1 4.0 4 0 0 4 4 4 2 NACHT domain DUF815 PF05673.8 EGG41533.1 - 2.6e-05 23.2 0.0 0.17 10.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PhoH PF02562.11 EGG41533.1 - 3.4e-05 23.1 0.4 0.26 10.4 0.1 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 EGG41533.1 - 5.9e-05 22.7 0.1 0.11 12.0 0.0 2.6 2 2 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EGG41533.1 - 6.6e-05 21.9 0.2 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EGG41533.1 - 9.1e-05 22.2 0.1 0.012 15.3 0.0 3.4 2 2 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 EGG41533.1 - 0.00015 21.6 0.2 0.079 12.7 0.0 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EGG41533.1 - 0.00018 21.1 0.1 0.16 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EGG41533.1 - 0.00042 19.3 0.1 0.53 9.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EGG41533.1 - 0.00056 19.6 1.5 2.7 7.6 0.0 4.1 2 1 1 3 3 3 0 NTPase Guanylate_kin PF00625.16 EGG41533.1 - 0.0011 18.4 0.3 3.9 6.8 0.0 4.3 3 1 1 4 4 4 0 Guanylate kinase NB-ARC PF00931.17 EGG41533.1 - 0.0016 17.3 0.9 0.76 8.5 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain UPF0079 PF02367.12 EGG41533.1 - 0.0016 18.0 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EGG41533.1 - 0.0024 16.8 0.0 1.1 8.0 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein SKI PF01202.17 EGG41533.1 - 0.0027 17.5 0.2 1.5 8.6 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase CPT PF07931.7 EGG41533.1 - 0.0035 16.9 0.1 0.13 11.9 0.0 2.6 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 EGG41533.1 - 0.0043 16.1 7.4 0.46 9.5 0.0 4.2 3 1 1 4 4 4 1 KaiC AFG1_ATPase PF03969.11 EGG41533.1 - 0.005 15.7 0.0 1.7 7.3 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase UFD1 PF03152.9 EGG41533.1 - 0.0067 15.5 0.1 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Bac_DnaA PF00308.13 EGG41533.1 - 0.0084 15.7 0.0 0.3 10.6 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein KTI12 PF08433.5 EGG41533.1 - 0.021 14.0 0.4 4.2 6.4 0.0 3.1 3 0 0 3 3 2 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 EGG41533.1 - 0.021 14.3 0.0 0.21 11.0 0.0 2.4 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EGG41533.1 - 0.022 14.2 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 EGG41533.1 - 0.023 14.2 0.0 6.1 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPT PF01745.11 EGG41533.1 - 0.027 13.6 0.5 1.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase PIF1 PF05970.9 EGG41533.1 - 0.036 13.0 0.0 3.9 6.3 0.0 2.8 2 0 0 2 2 2 0 PIF1-like helicase Torsin PF06309.6 EGG41533.1 - 0.055 13.3 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Torsin Vps4_C PF09336.5 EGG41533.1 - 0.1 12.5 2.8 9.9 6.1 0.0 3.8 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain DUF2443 PF10398.4 EGG41533.1 - 0.14 12.0 3.0 0.28 11.0 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2443) PPV_E1_C PF00519.12 EGG41533.1 - 0.17 10.4 0.0 3.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_23 PF13476.1 EGG41533.1 - 0.6 10.3 10.4 0.99 9.6 0.7 3.9 1 1 1 2 2 2 0 AAA domain Evr1_Alr PF04777.8 EGG41534.1 - 0.0052 16.6 0.1 0.0055 16.5 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family dCMP_cyt_deam_1 PF00383.17 EGG41534.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EGG41534.1 - 0.11 12.2 0.3 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase TFIIB PF00382.14 EGG41535.1 - 8.6e-34 115.1 2.9 4e-17 61.7 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.18 EGG41535.1 - 6.2e-06 25.7 0.2 0.045 13.3 0.0 2.1 1 1 1 2 2 2 2 Cyclin, N-terminal domain HTH_11 PF08279.7 EGG41535.1 - 1.3e-05 24.7 1.4 0.0055 16.3 0.1 2.6 2 0 0 2 2 2 2 HTH domain DUF1059 PF06348.6 EGG41536.1 - 6.3e-08 32.3 0.1 1.1e-07 31.5 0.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1059) CRCB PF02537.10 EGG41537.1 - 2.7e-24 85.3 6.6 3e-24 85.1 4.6 1.0 1 0 0 1 1 1 1 CrcB-like protein DUF2104 PF09877.4 EGG41537.1 - 0.017 15.0 0.4 0.017 15.0 0.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) CBS PF00571.23 EGG41538.1 - 1.3e-28 98.5 4.5 2.7e-14 52.6 0.1 2.2 2 0 0 2 2 2 2 CBS domain DisA_N PF02457.11 EGG41538.1 - 0.046 12.8 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Serpin PF00079.15 EGG41538.1 - 0.18 10.9 1.7 0.18 10.9 0.3 1.6 2 0 0 2 2 2 0 Serpin (serine protease inhibitor) Usp PF00582.21 EGG41539.1 - 5.6e-20 71.9 0.0 6.3e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.23 EGG41540.1 - 2.3e-29 100.9 0.5 5.6e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 CBS domain Oligomerisation PF02410.10 EGG41540.1 - 0.036 14.1 0.2 0.079 13.0 0.1 1.6 1 0 0 1 1 1 0 Oligomerisation domain FA_desaturase_2 PF03405.9 EGG41540.1 - 0.069 11.9 0.2 0.11 11.2 0.1 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Usp PF00582.21 EGG41542.1 - 2.7e-28 98.9 0.0 3.3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF1574 PF07611.6 EGG41542.1 - 0.0022 16.9 0.1 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1574) Utp13 PF08625.6 EGG41542.1 - 0.0089 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain AP_endonuc_2 PF01261.19 EGG41542.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Usp PF00582.21 EGG41543.1 - 2.5e-28 99.0 0.0 3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.21 EGG41544.1 - 3.9e-31 108.1 0.0 5.4e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.23 EGG41545.1 - 2.1e-32 110.6 6.4 3.2e-16 58.8 0.3 3.1 3 0 0 3 3 3 3 CBS domain CBS PF00571.23 EGG41546.1 - 1.4e-12 47.1 0.2 1.8e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 CBS domain CBS PF00571.23 EGG41547.1 - 2.5e-25 87.9 0.9 2.5e-07 30.3 0.1 4.3 4 0 0 4 4 4 4 CBS domain Ribosomal_S30AE PF02482.14 EGG41547.1 - 0.003 17.9 0.6 0.01 16.2 0.4 1.8 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein NLE PF08154.7 EGG41547.1 - 0.031 14.2 0.5 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 NLE (NUC135) domain Leptin PF02024.10 EGG41547.1 - 0.038 13.6 0.9 0.2 11.3 0.1 2.5 2 1 0 2 2 2 0 Leptin PAC2 PF09754.4 EGG41548.1 - 2e-30 106.3 0.0 2.3e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 PAC2 family HSP20 PF00011.16 EGG41549.1 - 5.2e-13 48.7 0.0 6.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EGG41549.1 - 0.00034 21.0 2.8 0.0013 19.2 1.9 1.9 1 1 0 1 1 1 1 CS domain DUF4097 PF13349.1 EGG41549.1 - 0.018 14.5 0.7 0.027 14.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) C1_1 PF00130.17 EGG41551.1 - 0.046 13.4 4.0 0.084 12.6 2.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-IS66 PF13005.2 EGG41551.1 - 0.19 11.7 6.4 0.57 10.1 0.9 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-FCS PF06467.9 EGG41551.1 - 1.3 8.7 8.6 7.1 6.3 0.5 3.1 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif OTT_1508_deam PF14441.1 EGG41551.1 - 2.8 7.7 5.3 55 3.5 3.7 2.0 1 1 0 1 1 1 0 OTT_1508-like deaminase P-II PF00543.17 EGG41552.1 - 1.3e-08 35.1 1.3 2.5e-08 34.3 0.9 1.5 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II FGGY_N PF00370.16 EGG41552.1 - 0.061 12.6 0.1 0.2 10.9 0.0 1.7 1 1 1 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain P-II PF00543.17 EGG41553.1 - 6.8e-13 48.9 0.6 8.6e-13 48.6 0.4 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Ammonium_transp PF00909.16 EGG41554.1 - 1.9e-113 378.9 29.1 2.1e-113 378.8 20.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HicB PF05534.7 EGG41555.1 - 0.09 12.3 0.4 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 HicB family IL5 PF02025.10 EGG41556.1 - 0.01 15.8 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Interleukin 5 Alginate_exp PF13372.1 EGG41556.1 - 0.046 12.3 0.0 0.053 12.1 0.0 1.0 1 0 0 1 1 1 0 Alginate export S_100 PF01023.14 EGG41556.1 - 0.048 12.9 4.1 3.3 7.0 0.2 2.5 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain CARDB PF07705.6 EGG41557.1 - 0.0037 17.2 0.5 0.0037 17.2 0.3 2.1 2 1 0 2 2 2 1 CARDB TFIIB PF00382.14 EGG41558.1 - 5.6e-34 115.7 6.6 1.4e-17 63.2 0.3 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG41558.1 - 2.6e-11 42.6 0.4 4.6e-11 41.8 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EGG41558.1 - 0.0011 18.5 0.1 0.057 12.9 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.11 EGG41558.1 - 0.0049 16.1 0.0 0.014 14.7 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 AAA_27 PF13514.1 EGG41558.1 - 0.0053 14.5 0.6 0.0066 14.2 0.4 1.0 1 0 0 1 1 1 1 AAA domain HTH_11 PF08279.7 EGG41558.1 - 0.0054 16.3 0.2 0.16 11.6 0.0 2.8 3 0 0 3 3 3 1 HTH domain zf-ribbon_3 PF13248.1 EGG41558.1 - 0.0069 15.5 1.0 0.014 14.5 0.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain HTH_AsnC-type PF13404.1 EGG41558.1 - 0.018 14.5 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.7 EGG41558.1 - 0.018 14.5 0.2 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 RRN7 PF11781.3 EGG41558.1 - 0.033 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Baculo_ME53 PF06061.6 EGG41558.1 - 0.039 12.9 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 DZR PF12773.2 EGG41558.1 - 0.04 13.7 1.0 0.088 12.6 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon RPA_interact_C PF14768.1 EGG41558.1 - 0.089 13.1 0.7 0.2 12.0 0.1 1.9 2 0 0 2 2 1 0 Replication protein A interacting C-terminal zf-FPG_IleRS PF06827.9 EGG41558.1 - 0.097 12.3 0.5 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS HTH_23 PF13384.1 EGG41558.1 - 0.15 11.7 2.4 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain zinc_ribbon_2 PF13240.1 EGG41558.1 - 0.19 11.2 0.3 0.19 11.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain APS_kinase PF01583.15 EGG41559.1 - 2.6e-50 170.1 0.0 3.1e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EGG41559.1 - 4.2e-08 33.1 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG41559.1 - 2.5e-06 28.3 0.0 4.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG41559.1 - 1.6e-05 25.2 0.0 3.4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG41559.1 - 0.00018 20.6 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 EGG41559.1 - 0.00045 19.5 0.0 0.00064 19.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EGG41559.1 - 0.034 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EGG41559.1 - 0.04 13.5 0.1 5.2 6.6 0.0 2.3 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Arf PF00025.16 EGG41559.1 - 0.098 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Inositol_P PF00459.20 EGG41560.1 - 8e-22 77.8 0.5 9.1e-22 77.6 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 EGG41560.1 - 0.0012 17.8 0.1 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase CRPA PF05745.6 EGG41561.1 - 0.043 13.5 2.7 0.049 13.4 1.9 1.1 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Lactate_perm PF02652.9 EGG41561.1 - 0.053 12.0 3.0 0.058 11.8 2.1 1.0 1 0 0 1 1 1 0 L-lactate permease DUF3671 PF12420.3 EGG41561.1 - 0.058 13.3 1.9 0.073 13.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function 7TMR-DISM_7TM PF07695.6 EGG41561.1 - 0.078 12.6 1.2 0.086 12.5 0.8 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF2842 PF11003.3 EGG41561.1 - 0.4 10.5 5.7 5 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) adh_short_C2 PF13561.1 EGG41562.1 - 1.5e-40 139.4 0.0 2e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG41562.1 - 5.6e-29 101.2 0.0 6.9e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG41562.1 - 1.5e-07 31.2 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG41562.1 - 0.0027 17.1 0.2 0.0045 16.4 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EGG41562.1 - 0.0054 15.8 0.1 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 EGG41562.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain 3HCDH_N PF02737.13 EGG41562.1 - 0.019 14.6 0.2 0.029 14.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGG41562.1 - 0.077 12.7 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3836 PF12930.2 EGG41563.1 - 0.002 17.6 0.2 0.0025 17.2 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF3836) TFIIB PF00382.14 EGG41564.1 - 1.5e-34 117.6 1.7 8.2e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG41564.1 - 4.3e-10 38.7 0.6 7.2e-10 38.0 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.11 EGG41564.1 - 0.00024 20.3 0.0 0.025 13.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.18 EGG41564.1 - 0.00049 19.6 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain A2L_zn_ribbon PF08792.5 EGG41564.1 - 0.0012 18.2 0.7 0.0021 17.4 0.5 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain Cyclin_C PF02984.14 EGG41564.1 - 0.011 15.6 0.0 2.6 7.9 0.0 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain HTH_11 PF08279.7 EGG41564.1 - 0.02 14.5 1.4 0.69 9.6 0.0 2.8 3 0 0 3 3 3 0 HTH domain Sigma70_r4_2 PF08281.7 EGG41564.1 - 0.061 12.7 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DZR PF12773.2 EGG41564.1 - 0.15 11.8 1.2 0.31 10.8 0.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGG41564.1 - 0.17 11.1 0.8 0.36 10.0 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Snf7 PF03357.16 EGG41565.1 - 5.4e-05 22.6 5.7 9.1e-05 21.9 3.9 1.4 1 1 0 1 1 1 1 Snf7 Inp1 PF12634.2 EGG41565.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 RVT_N PF13655.1 EGG41565.1 - 0.015 15.3 1.2 0.32 11.0 0.1 2.7 1 1 1 2 2 2 0 N-terminal domain of reverse transcriptase RHSP PF07999.6 EGG41565.1 - 0.031 12.8 0.1 0.036 12.6 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein Nup54 PF13874.1 EGG41565.1 - 0.047 13.3 2.9 0.11 12.1 2.0 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.3 EGG41565.1 - 0.05 13.4 1.0 0.05 13.4 0.7 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BRE1 PF08647.6 EGG41565.1 - 0.054 13.4 2.3 0.15 12.0 0.3 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.7 EGG41565.1 - 0.056 13.2 4.6 0.72 9.6 3.2 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIVA PF05103.8 EGG41565.1 - 0.21 11.6 2.4 0.81 9.7 0.6 2.2 2 0 0 2 2 2 0 DivIVA protein DUF1664 PF07889.7 EGG41566.1 - 0.00011 22.0 5.4 0.00016 21.4 3.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.6 EGG41566.1 - 0.00043 19.0 10.7 0.0005 18.8 7.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.7 EGG41566.1 - 0.0017 18.1 6.9 0.0028 17.3 4.8 1.4 1 0 0 1 1 1 1 Laminin Domain II Tropomyosin_1 PF12718.2 EGG41566.1 - 0.0018 18.1 17.7 0.0063 16.3 9.9 2.4 1 1 1 2 2 2 2 Tropomyosin like DUF812 PF05667.6 EGG41566.1 - 0.0058 15.2 7.6 0.0072 14.8 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3450 PF11932.3 EGG41566.1 - 0.0069 15.6 1.8 0.01 15.1 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IncA PF04156.9 EGG41566.1 - 0.011 15.2 8.3 0.014 15.0 5.7 1.3 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 EGG41566.1 - 0.016 13.7 8.9 0.016 13.7 6.2 1.1 1 0 0 1 1 1 0 AAA domain Sipho_Gp157 PF05565.6 EGG41566.1 - 0.019 14.5 11.4 0.26 10.8 3.4 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 Baculo_PEP_C PF04513.7 EGG41566.1 - 0.023 14.5 0.2 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 EGG41566.1 - 0.024 14.9 4.1 0.024 14.9 2.9 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 EGG41566.1 - 0.048 13.6 13.3 0.06 13.3 7.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin PF02996.12 EGG41566.1 - 0.061 12.9 8.4 0.12 12.0 1.3 2.6 1 1 2 3 3 3 0 Prefoldin subunit Reo_sigmaC PF04582.7 EGG41566.1 - 0.061 12.4 0.5 0.063 12.4 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Syntaxin PF00804.20 EGG41566.1 - 0.067 13.3 13.3 0.03 14.4 6.4 2.2 1 1 2 3 3 3 0 Syntaxin Matrilin_ccoil PF10393.4 EGG41566.1 - 0.072 12.4 1.5 1 8.7 0.2 2.8 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin FemAB PF02388.11 EGG41566.1 - 0.098 11.3 1.9 0.13 10.8 1.3 1.2 1 0 0 1 1 1 0 FemAB family NPV_P10 PF05531.7 EGG41566.1 - 0.11 12.7 7.0 0.58 10.4 1.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.1 EGG41566.1 - 0.14 11.5 12.0 0.042 13.2 6.1 1.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4363 PF14276.1 EGG41566.1 - 0.16 11.7 3.7 0.27 10.9 2.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) FliD_N PF02465.13 EGG41566.1 - 0.22 11.9 1.7 0.33 11.3 0.1 2.1 2 1 1 3 3 1 0 Flagellar hook-associated protein 2 N-terminus V_ATPase_I PF01496.14 EGG41566.1 - 0.22 9.3 6.3 0.23 9.2 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 EGG41566.1 - 0.32 11.3 5.3 1.4 9.2 2.9 2.1 1 1 0 1 1 1 0 Snapin/Pallidin DUF948 PF06103.6 EGG41566.1 - 0.4 10.5 4.5 1.4 8.8 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HR1 PF02185.11 EGG41566.1 - 0.4 10.4 11.4 0.4 10.4 7.0 1.8 1 1 1 2 2 2 0 Hr1 repeat APG6 PF04111.7 EGG41566.1 - 0.45 9.5 9.0 0.5 9.3 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EGG41566.1 - 0.45 10.6 8.9 4.4 7.4 5.4 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mnd1 PF03962.10 EGG41566.1 - 0.45 10.1 11.7 0.84 9.2 8.1 1.7 1 1 0 1 1 1 0 Mnd1 family Spectrin PF00435.16 EGG41566.1 - 0.47 10.7 7.4 0.86 9.9 3.3 2.4 1 1 1 2 2 2 0 Spectrin repeat YlbD_coat PF14071.1 EGG41566.1 - 0.49 10.4 7.2 6 6.9 0.5 2.7 1 1 2 3 3 3 0 Putative coat protein HisKA PF00512.20 EGG41566.1 - 0.51 10.3 2.5 1.8 8.6 1.6 2.1 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Flagellin_C PF00700.16 EGG41566.1 - 0.55 10.4 4.1 2.3 8.4 0.1 2.3 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region Atg14 PF10186.4 EGG41566.1 - 0.57 9.0 7.7 0.61 8.9 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 EGG41566.1 - 0.88 10.0 4.7 10 6.6 2.3 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.13 EGG41566.1 - 1.6 7.6 5.6 2.1 7.3 3.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CCDC-167 PF15188.1 EGG41566.1 - 1.8 8.5 7.5 3.3 7.7 4.7 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Rabaptin PF03528.10 EGG41566.1 - 1.8 8.4 11.1 11 6.0 1.9 2.2 1 1 1 2 2 2 0 Rabaptin Fib_alpha PF08702.5 EGG41566.1 - 2.6 8.1 9.5 1.5 8.9 3.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF848 PF05852.6 EGG41566.1 - 3.2 7.5 8.8 3.3 7.5 4.7 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Osmo_CC PF08946.5 EGG41566.1 - 3.9 7.5 14.2 1.8 8.6 4.0 3.5 1 1 3 4 4 4 0 Osmosensory transporter coiled coil CENP-Q PF13094.1 EGG41566.1 - 4.3 7.3 11.4 0.35 10.8 4.8 1.5 2 0 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fmp27_WPPW PF10359.4 EGG41566.1 - 4.5 5.5 10.1 0.75 8.1 4.1 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMF_DNA_bd PF12329.3 EGG41566.1 - 4.5 7.1 21.0 0.03 14.1 7.0 2.7 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.4 EGG41566.1 - 6.5 6.9 7.1 3.5 7.8 2.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF724 PF05266.9 EGG41566.1 - 8.7 5.9 11.1 2.1 7.8 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HTH_45 PF14947.1 EGG41567.1 - 3e-10 39.7 0.0 3.7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 EGG41567.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 EGG41567.1 - 0.0004 20.6 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.1 EGG41567.1 - 0.029 13.9 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF2250 PF10007.4 EGG41567.1 - 0.05 13.5 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 EGG41567.1 - 0.061 13.0 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Mrr_N PF14338.1 EGG41567.1 - 0.062 13.3 0.0 0.6 10.2 0.0 1.9 1 1 1 2 2 2 0 Mrr N-terminal domain HTH_20 PF12840.2 EGG41567.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.15 EGG41567.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.1 EGG41568.1 - 0.0033 16.7 0.0 0.0079 15.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Ribosomal_L22 PF00237.14 EGG41569.1 - 0.0063 16.4 0.8 0.076 12.9 0.0 2.9 2 2 1 3 3 3 1 Ribosomal protein L22p/L17e FCD PF07729.7 EGG41569.1 - 0.066 13.5 1.3 3 8.1 0.0 3.1 3 1 1 4 4 4 0 FCD domain DUF3596 PF12167.3 EGG41569.1 - 0.26 10.8 4.1 0.35 10.4 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3596) TPR_19 PF14559.1 EGG41569.1 - 0.29 11.4 9.5 5.6 7.3 0.1 4.6 4 3 1 5 5 5 0 Tetratricopeptide repeat GlcNAc_2-epim PF07221.6 EGG41569.1 - 0.36 9.7 3.4 0.38 9.7 0.5 2.0 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hyd_65N_2 PF14498.1 EGG41569.1 - 0.56 9.8 0.1 0.56 9.8 0.0 2.9 3 1 0 3 3 3 0 Glycosyl hydrolase family 65, N-terminal domain Imm42 PF15601.1 EGG41569.1 - 0.61 9.5 8.7 1.2 8.5 0.2 3.8 2 1 1 4 4 4 0 Immunity protein 42 GTPase_Cys_C PF12631.2 EGG41569.1 - 0.95 9.9 8.5 4.2 7.8 0.3 3.5 3 1 1 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE SRA1 PF07304.6 EGG41569.1 - 1.2 8.8 6.4 5.8 6.6 0.8 2.9 2 1 1 3 3 3 0 Steroid receptor RNA activator (SRA1) TPR_12 PF13424.1 EGG41569.1 - 5.1 7.1 7.0 40 4.2 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat MFS_2 PF13347.1 EGG41570.1 - 0.0081 14.5 1.8 0.0085 14.5 1.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Tetraspannin PF00335.15 EGG41570.1 - 0.33 10.2 3.3 0.38 9.9 2.3 1.0 1 0 0 1 1 1 0 Tetraspanin family Yip1 PF04893.12 EGG41570.1 - 0.34 10.4 3.5 0.41 10.1 2.4 1.1 1 0 0 1 1 1 0 Yip1 domain DUF2892 PF11127.3 EGG41570.1 - 0.82 9.5 3.9 0.97 9.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DUF3185 PF11381.3 EGG41570.1 - 1.8 8.3 7.7 68 3.3 5.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) NfeD PF01957.13 EGG41570.1 - 1.9 8.6 5.5 2.8 8.0 3.8 1.3 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2530 PF10745.4 EGG41570.1 - 2.1 8.3 4.6 3.7 7.5 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) DUF308 PF03729.8 EGG41570.1 - 4.1 7.4 8.1 24 5.0 5.7 1.9 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) Fer4_14 PF13394.1 EGG41571.1 - 5.9e-16 58.5 1.2 9.5e-16 57.8 0.2 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EGG41571.1 - 7.8e-15 55.2 0.7 5.5e-14 52.4 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 EGG41571.1 - 1.2e-10 41.8 0.1 1.6e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily TM1586_NiRdase PF14512.1 EGG41571.1 - 0.065 12.4 0.2 0.22 10.6 0.0 1.9 2 1 0 2 2 2 0 Putative TM nitroreductase GTP_cyclohydroI PF01227.17 EGG41572.1 - 3.6e-64 215.3 0.1 4.2e-64 215.1 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EGG41572.1 - 0.0026 17.6 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein PDEase_I PF00233.14 EGG41572.1 - 0.055 13.2 0.0 0.097 12.4 0.0 1.6 1 1 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase OST-HTH PF12872.2 EGG41572.1 - 0.12 12.2 0.0 9 6.2 0.0 2.3 2 0 0 2 2 2 0 OST-HTH/LOTUS domain DUF1761 PF08570.5 EGG41573.1 - 0.041 13.8 1.5 0.061 13.3 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) DUF3262 PF11660.3 EGG41573.1 - 0.071 13.2 0.6 0.15 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) PQ-loop PF04193.9 EGG41573.1 - 0.2 11.2 0.5 0.2 11.2 0.3 1.6 2 0 0 2 2 2 0 PQ loop repeat Class_IIIsignal PF04021.7 EGG41573.1 - 7.6 6.4 8.6 17 5.3 0.4 2.3 2 0 0 2 2 2 0 Class III signal peptide QueC PF06508.8 EGG41574.1 - 2e-47 161.2 0.0 2.3e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EGG41574.1 - 0.00015 21.4 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 EGG41574.1 - 0.00055 19.0 0.0 0.00066 18.8 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase NAD_synthase PF02540.12 EGG41574.1 - 0.0058 15.5 0.0 0.008 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.15 EGG41574.1 - 0.028 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 PP-loop family GHMP_kinases_N PF00288.21 EGG41575.1 - 3.4e-16 59.0 1.5 7.3e-16 57.9 1.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGG41575.1 - 3.5e-07 30.3 0.0 6.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal ATP_bind_1 PF03029.12 EGG41576.1 - 2.7e-56 190.8 0.0 2.9e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EGG41576.1 - 0.00024 20.5 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 EGG41576.1 - 0.0013 17.8 0.1 0.0034 16.3 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EGG41576.1 - 0.002 16.9 0.0 0.0039 16.0 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EGG41576.1 - 0.0021 18.0 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGG41576.1 - 0.0026 18.5 0.0 0.0056 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG41576.1 - 0.0034 17.6 0.0 0.0064 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGG41576.1 - 0.0039 17.1 0.2 0.013 15.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.17 EGG41576.1 - 0.023 14.1 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGG41576.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGG41576.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGG41576.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 EGG41576.1 - 0.091 12.4 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 NTPase KaiC PF06745.8 EGG41576.1 - 0.1 11.6 0.2 0.25 10.4 0.1 1.7 1 1 0 1 1 1 0 KaiC PduV-EutP PF10662.4 EGG41576.1 - 0.23 10.9 1.1 11 5.4 0.0 3.2 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EGG41576.1 - 0.34 10.3 1.9 7.9 5.8 1.3 2.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0104 PF03706.8 EGG41577.1 - 4.8e-23 81.8 20.2 6.8e-23 81.3 14.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) SIS PF01380.17 EGG41577.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 SIS domain adh_short PF00106.20 EGG41578.1 - 6.1e-37 127.0 0.0 7.5e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG41578.1 - 3.8e-15 55.9 0.1 5.6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG41578.1 - 4.9e-11 42.8 0.1 6.1e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGG41578.1 - 0.00028 20.9 0.0 0.0019 18.2 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGG41578.1 - 0.0022 17.7 0.1 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EGG41578.1 - 0.0027 16.9 0.0 0.0065 15.6 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EGG41578.1 - 0.0076 15.1 0.1 0.0094 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.10 EGG41578.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein BBP1_C PF15272.1 EGG41579.1 - 0.082 12.4 0.7 0.11 11.9 0.5 1.3 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TF_Zn_Ribbon PF08271.7 EGG41580.1 - 0.033 13.4 0.6 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Rpr2 PF04032.11 EGG41580.1 - 0.036 13.9 0.4 0.036 13.9 0.3 1.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_L32p PF01783.18 EGG41580.1 - 0.099 12.8 0.1 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L32p protein family OrfB_Zn_ribbon PF07282.6 EGG41580.1 - 0.12 12.0 0.5 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Glyco_trans_1_3 PF13528.1 EGG41581.1 - 1e-10 41.3 0.0 2.3e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Alg14 PF08660.6 EGG41581.1 - 0.0034 17.3 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like tRNA_deacylase PF04414.7 EGG41581.1 - 0.055 12.5 1.0 1 8.4 0.0 2.6 2 1 1 3 3 3 0 D-aminoacyl-tRNA deacylase WhiA_N PF10298.4 EGG41582.1 - 0.0057 16.4 0.5 0.45 10.3 0.0 3.0 3 0 0 3 3 3 2 WhiA N-terminal LAGLIDADG-like domain PAPS_reduct PF01507.14 EGG41583.1 - 1.8e-43 148.4 0.0 2.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.12 EGG41584.1 - 2.4e-89 298.2 0.1 3.8e-89 297.6 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EGG41584.1 - 1.5e-46 157.7 0.0 3.3e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain PsbI PF02532.9 EGG41585.1 - 0.84 9.3 3.9 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) HhH-GPD PF00730.20 EGG41586.1 - 8.6e-25 87.1 0.1 1.1e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGG41586.1 - 9.7e-09 34.4 0.0 3.4e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2400 PF09674.5 EGG41586.1 - 0.00069 19.3 0.3 0.0054 16.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_5 PF14520.1 EGG41586.1 - 0.0013 18.8 0.4 0.013 15.6 0.3 2.2 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EGG41586.1 - 0.011 15.6 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4028 PF13220.1 EGG41586.1 - 0.061 12.9 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) DUF521 PF04412.8 EGG41587.1 - 1.5e-99 333.2 0.0 2.2e-99 332.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 EGG41588.1 - 6.7e-31 105.8 0.1 9.4e-31 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF126 AMMECR1 PF01871.12 EGG41589.1 - 4.7e-59 198.3 0.0 5.7e-59 198.0 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Inhibitor_I48 PF10467.4 EGG41589.1 - 0.08 12.8 0.2 3.5 7.5 0.0 2.3 1 1 1 2 2 2 0 Peptidase inhibitor clitocypin Mut7-C PF01927.11 EGG41590.1 - 2.1e-39 134.8 0.6 2.3e-39 134.6 0.4 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain Mcm10 PF09332.6 EGG41590.1 - 0.081 12.2 2.5 0.095 12.0 1.7 1.2 1 0 0 1 1 1 0 Mcm10 replication factor DUF4342 PF14242.1 EGG41590.1 - 4.5 7.1 6.1 25 4.7 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4342) FbpA PF05833.6 EGG41591.1 - 8e-39 133.4 5.6 1.1e-38 132.9 3.9 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EGG41591.1 - 2.9e-15 55.9 0.0 8.4e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Lge1 PF11488.3 EGG41591.1 - 0.21 11.8 4.3 8.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Tweety PF04906.8 EGG41591.1 - 3.1 6.0 7.4 3.5 5.9 1.0 2.2 1 1 0 2 2 2 0 Tweety 7TM_GPCR_Srsx PF10320.4 EGG41592.1 - 0.0058 15.8 4.1 0.0081 15.3 2.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Rab5ip PF07019.7 EGG41592.1 - 0.006 16.6 6.3 0.015 15.4 4.3 1.6 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) ECF-ribofla_trS PF07155.7 EGG41592.1 - 0.019 14.7 2.4 0.025 14.3 1.6 1.1 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component RSN1_TM PF13967.1 EGG41592.1 - 0.019 14.5 0.3 0.19 11.3 0.0 2.0 1 1 1 2 2 2 0 Late exocytosis, associated with Golgi transport DUF443 PF04276.7 EGG41592.1 - 0.037 13.4 1.2 0.086 12.2 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF443) Colicin_V PF02674.11 EGG41592.1 - 0.068 13.0 4.4 0.12 12.2 3.1 1.4 1 1 0 1 1 1 0 Colicin V production protein Multi_Drug_Res PF00893.14 EGG41592.1 - 0.073 13.5 2.2 0.11 12.9 1.6 1.3 1 1 0 1 1 1 0 Small Multidrug Resistance protein DUF1686 PF07937.6 EGG41592.1 - 0.083 12.5 0.2 0.16 11.6 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1686) DUF202 PF02656.10 EGG41592.1 - 0.087 13.0 6.0 2.6 8.3 4.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) PBP1_TM PF14812.1 EGG41592.1 - 0.13 12.5 0.9 0.23 11.7 0.2 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EmrE PF13536.1 EGG41592.1 - 0.18 11.9 5.0 0.13 12.4 2.0 1.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Methyltransf_18 PF12847.2 EGG41593.1 - 1.4e-17 64.2 0.2 2.4e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG41593.1 - 1.2e-14 54.1 3.6 3e-14 52.8 1.7 1.8 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGG41593.1 - 1.7e-11 43.8 1.9 2.2e-11 43.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EGG41593.1 - 2.2e-11 43.6 0.2 2.7e-11 43.3 0.2 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGG41593.1 - 2.7e-10 39.8 0.4 8e-10 38.3 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGG41593.1 - 3.8e-09 35.8 0.4 2.3e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 EGG41593.1 - 1.9e-08 34.6 0.0 4.1e-08 33.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41593.1 - 3.8e-07 30.5 0.1 1.8e-06 28.3 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG41593.1 - 3.8e-07 30.1 0.0 9.9e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGG41593.1 - 1.5e-06 27.5 0.0 2.3e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 EGG41593.1 - 2.3e-06 27.1 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 EGG41593.1 - 3.1e-06 26.4 0.3 4e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF633 PF04816.7 EGG41593.1 - 3.5e-06 26.4 1.4 4.5e-06 26.1 1.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) GidB PF02527.10 EGG41593.1 - 3.6e-06 26.2 0.4 6e-06 25.5 0.3 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.1 EGG41593.1 - 3.9e-06 27.1 0.0 1.6e-05 25.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EGG41593.1 - 4.8e-06 26.2 0.1 5.5e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EGG41593.1 - 1.9e-05 24.2 0.2 4.4e-05 23.1 0.1 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 GCD14 PF08704.5 EGG41593.1 - 0.00014 21.4 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.5 EGG41593.1 - 0.00016 21.2 0.2 0.00028 20.4 0.2 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DOT1 PF08123.8 EGG41593.1 - 0.00034 19.9 0.1 0.00097 18.4 0.1 1.8 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 EGG41593.1 - 0.00073 18.6 0.1 0.00085 18.4 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_5 PF01795.14 EGG41593.1 - 0.0069 15.7 0.1 0.015 14.6 0.0 1.5 1 1 1 2 2 2 1 MraW methylase family RrnaAD PF00398.15 EGG41593.1 - 0.0078 15.2 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase N6_N4_Mtase PF01555.13 EGG41593.1 - 0.015 14.7 0.2 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 DNA methylase TehB PF03848.9 EGG41593.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 EGG41593.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EGG41593.1 - 0.05 13.0 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 EGG41593.1 - 0.053 12.8 0.0 0.83 8.9 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 EGG41593.1 - 0.083 12.5 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EGG41593.1 - 0.087 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) NNMT_PNMT_TEMT PF01234.12 EGG41593.1 - 0.1 11.5 0.1 1 8.2 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family TP_methylase PF00590.15 EGG41594.1 - 2.6e-51 174.3 0.0 2.9e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.15 EGG41595.1 - 1.5e-43 149.0 0.0 1.7e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Aldolase PF01081.14 EGG41595.1 - 0.022 13.9 0.1 0.047 12.8 0.1 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase V-ATPase_H_N PF03224.9 EGG41595.1 - 0.028 13.5 0.5 0.06 12.4 0.0 1.8 3 0 0 3 3 3 0 V-ATPase subunit H PrpR_N PF06506.6 EGG41595.1 - 0.032 13.6 0.5 0.61 9.4 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Radical_SAM PF04055.16 EGG41595.1 - 0.032 14.4 0.1 0.061 13.4 0.1 1.6 1 1 0 1 1 1 0 Radical SAM superfamily Tmemb_170 PF10190.4 EGG41595.1 - 0.033 14.2 0.6 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Putative transmembrane protein 170 DUF2570 PF10828.3 EGG41597.1 - 0.00054 19.5 0.3 0.00056 19.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) tRNA_anti-like PF12869.2 EGG41597.1 - 0.013 14.9 0.3 0.014 14.8 0.2 1.0 1 0 0 1 1 1 0 tRNA_anti-like DUF929 PF06053.6 EGG41597.1 - 0.019 14.0 3.3 0.021 13.9 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF929) OppC_N PF12911.2 EGG41597.1 - 0.086 12.2 0.4 0.095 12.0 0.3 1.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C 4HB_MCP_1 PF12729.2 EGG41597.1 - 0.12 11.7 0.9 0.12 11.7 0.6 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF3139 PF11337.3 EGG41597.1 - 0.71 10.1 4.7 0.94 9.7 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DUF1083 PF06452.6 EGG41598.1 - 0.00076 19.3 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1083) Lentivirus_VIF PF05851.6 EGG41599.1 - 0.09 11.4 0.1 0.17 10.5 0.1 1.4 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Snf7 PF03357.16 EGG41600.1 - 0.008 15.5 7.4 0.022 14.1 5.1 1.8 1 1 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 EGG41600.1 - 0.021 14.6 2.4 0.56 10.0 0.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF694 PF05107.7 EGG41600.1 - 0.051 12.7 0.1 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF694) Spc24 PF08286.6 EGG41600.1 - 0.19 11.4 2.6 0.48 10.1 0.2 2.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 PTRF_SDPR PF15237.1 EGG41600.1 - 0.34 10.2 4.7 0.53 9.6 3.3 1.3 1 0 0 1 1 1 0 PTRF/SDPR family NPV_P10 PF05531.7 EGG41600.1 - 0.87 9.8 3.3 25 5.2 0.4 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CCDC155 PF14662.1 EGG41600.1 - 1.1 8.8 7.1 0.18 11.3 2.3 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF745 PF05335.8 EGG41600.1 - 4.9 6.6 6.8 3.9 6.9 2.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Asp_Glu_race PF01177.17 EGG41601.1 - 7.5e-22 78.3 0.0 8.8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Cupredoxin_1 PF13473.1 EGG41604.1 - 0.00049 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.15 EGG41604.1 - 0.0011 19.1 1.6 0.0037 17.4 0.0 2.4 2 2 1 3 3 3 1 Copper binding proteins, plastocyanin/azurin family IF3_C PF00707.17 EGG41604.1 - 0.02 14.5 0.0 0.78 9.5 0.1 2.7 2 1 1 3 3 3 0 Translation initiation factor IF-3, C-terminal domain BACON PF13004.2 EGG41604.1 - 0.074 13.2 0.1 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal SGL PF08450.7 EGG41606.1 - 5e-16 58.8 0.1 0.00021 20.7 0.0 5.1 1 1 4 5 5 5 5 SMP-30/Gluconolaconase/LRE-like region CopD PF05425.8 EGG41606.1 - 4.6e-13 49.2 1.9 4.6e-13 49.2 1.3 2.8 3 0 0 3 3 3 1 Copper resistance protein D CopC PF04234.7 EGG41606.1 - 5.8e-13 49.2 0.0 1.5e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 CopC domain Reg_prop PF07494.6 EGG41606.1 - 4.6e-08 32.1 11.3 5.8 7.2 0.2 8.3 8 0 0 8 8 8 2 Two component regulator propeller YtkA PF13115.1 EGG41606.1 - 0.0085 16.4 0.0 0.063 13.6 0.0 2.3 2 0 0 2 2 2 1 YtkA-like PPC PF04151.10 EGG41606.1 - 0.088 13.7 0.4 0.49 11.3 0.3 2.3 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain DUF4149 PF13664.1 EGG41606.1 - 1.4 9.0 11.9 0.17 11.9 2.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) ABC-3 PF00950.12 EGG41607.1 - 1.4e-64 217.9 38.2 1.5e-64 217.7 26.5 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.13 EGG41607.1 - 8.6e-08 31.3 32.4 8.6e-08 31.3 22.5 1.8 1 1 1 2 2 2 1 FecCD transport family DUF2953 PF11167.3 EGG41607.1 - 0.79 9.6 8.9 11 6.0 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2953) ABC_tran PF00005.22 EGG41608.1 - 9.1e-37 126.4 0.1 9e-36 123.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGG41608.1 - 3.3e-15 56.8 3.3 2.5e-13 50.6 2.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EGG41608.1 - 2.3e-07 30.2 3.4 0.0026 16.8 1.3 2.1 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EGG41608.1 - 1.1e-05 24.8 1.5 0.00042 19.6 1.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGG41608.1 - 3.4e-05 23.2 0.1 6.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EGG41608.1 - 0.00039 19.8 0.2 0.63 9.4 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_23 PF13476.1 EGG41608.1 - 0.00088 19.6 6.8 0.0035 17.6 4.7 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGG41608.1 - 0.00093 19.1 0.6 0.0019 18.1 0.4 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_13 PF13166.1 EGG41608.1 - 0.0025 16.3 3.4 0.18 10.1 0.6 2.1 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGG41608.1 - 0.0059 16.5 0.0 0.2 11.6 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGG41608.1 - 0.0077 15.4 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EGG41608.1 - 0.016 15.3 1.1 0.13 12.4 0.8 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG41608.1 - 0.016 15.3 0.4 0.089 12.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGG41608.1 - 0.017 14.6 0.6 0.29 10.5 0.2 2.3 1 1 2 3 3 3 0 AAA-like domain AAA_14 PF13173.1 EGG41608.1 - 0.025 14.4 0.9 0.74 9.7 0.6 2.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGG41608.1 - 0.028 14.1 0.2 0.044 13.4 0.2 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EGG41608.1 - 0.043 13.8 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EGG41608.1 - 0.052 13.0 0.0 0.1 12.0 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NAP PF00956.13 EGG41608.1 - 0.081 12.0 0.9 0.11 11.5 0.5 1.3 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) Miro PF08477.8 EGG41608.1 - 0.098 13.1 0.1 0.3 11.5 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 EGG41608.1 - 0.11 11.9 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGG41608.1 - 0.12 13.2 1.2 0.72 10.6 0.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGG41608.1 - 0.12 12.2 0.1 0.32 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGG41608.1 - 1.8 8.3 5.7 12 5.5 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF87 TroA PF01297.12 EGG41609.1 - 5.8e-79 264.9 0.3 6.6e-79 264.7 0.2 1.0 1 0 0 1 1 1 1 Periplasmic solute binding protein family NikR_C PF08753.6 EGG41610.1 - 1.1e-10 41.2 2.3 1.7e-10 40.6 1.6 1.3 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.16 EGG41610.1 - 4.6e-05 23.1 0.1 7e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF2191 PF09957.4 EGG41610.1 - 0.0032 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2191) DUF1327 PF07041.6 EGG41610.1 - 0.094 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) LON PF02190.11 EGG41612.1 - 3.6e-09 36.5 0.1 5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain OTCace_N PF02729.16 EGG41613.1 - 1.7e-40 137.9 0.0 2.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EGG41613.1 - 2e-37 128.4 0.0 2.9e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PyrI PF01948.13 EGG41614.1 - 1.1e-33 115.1 2.5 1.1e-33 115.1 1.7 1.4 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.10 EGG41614.1 - 3.5e-15 55.1 2.1 5.7e-15 54.4 1.5 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1936 PF09151.5 EGG41614.1 - 0.02 14.3 0.2 0.053 13.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) ATP-synt_C PF00137.16 EGG41615.1 - 3.9e-20 71.5 17.4 3.9e-20 71.5 12.1 1.9 2 0 0 2 2 2 1 ATP synthase subunit C DUF3693 PF12472.3 EGG41615.1 - 0.66 9.6 4.9 7.3 6.2 0.1 2.5 2 0 0 2 2 2 0 Phage related protein ATP-synt_D PF01813.12 EGG41616.1 - 4.9e-53 179.6 7.9 5.5e-53 179.4 5.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit D DUF1395 PF07160.7 EGG41616.1 - 0.77 9.2 8.3 1.8 8.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1395) DUF1019 PF06254.6 EGG41616.1 - 2.9 8.1 7.3 0.62 10.2 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1019) GreA_GreB_N PF03449.10 EGG41616.1 - 6 6.9 7.8 2.1 8.4 1.3 2.6 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal ATP-synt_ab PF00006.20 EGG41617.1 - 1.7e-65 220.5 0.0 2.4e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGG41617.1 - 1e-13 51.7 0.2 1.9e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGG41617.1 - 3.1e-11 43.2 2.3 7.5e-11 42.0 1.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGG41617.1 - 8.4e-05 22.3 1.8 0.00016 21.5 0.5 2.1 2 0 0 2 2 2 1 HAS barrel domain ATP-synt_ab PF00006.20 EGG41618.1 - 1.3e-95 319.0 0.0 1.9e-95 318.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGG41618.1 - 4.6e-14 52.8 1.0 7.8e-14 52.1 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGG41618.1 - 1.2e-12 47.7 0.6 3.1e-12 46.5 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.1 EGG41618.1 - 0.0071 16.0 0.1 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EGG41618.1 - 0.065 13.3 0.2 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.7 EGG41618.1 - 0.1 10.9 0.4 0.16 10.3 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) vATP-synt_E PF01991.13 EGG41619.1 - 1.4e-21 76.7 7.2 3.1e-21 75.5 4.6 1.8 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit FliH PF02108.11 EGG41619.1 - 0.0021 17.9 0.6 0.0099 15.7 0.2 2.1 1 1 1 2 2 2 1 Flagellar assembly protein FliH PhoU PF01895.14 EGG41619.1 - 0.0056 17.0 0.8 0.021 15.2 0.5 2.0 1 1 0 1 1 1 1 PhoU domain DUF3236 PF11576.3 EGG41619.1 - 0.0068 15.8 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3236) Prominin PF05478.6 EGG41619.1 - 0.049 11.1 1.2 0.066 10.7 0.8 1.1 1 0 0 1 1 1 0 Prominin OSCP PF00213.13 EGG41619.1 - 0.063 13.1 5.1 0.11 12.3 3.4 1.6 1 1 0 1 1 1 0 ATP synthase delta (OSCP) subunit Imm22 PF15592.1 EGG41619.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 22 YtzH PF14165.1 EGG41619.1 - 0.13 12.5 3.7 5.2 7.3 0.0 2.8 3 0 0 3 3 3 0 YtzH-like protein DUF1399 PF07173.7 EGG41619.1 - 0.9 9.8 2.8 3.2 8.0 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1399) V_ATPase_I PF01496.14 EGG41620.1 - 1.9e-54 184.8 17.8 1.3e-53 182.0 12.3 1.9 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family ABC_trans_N PF14510.1 EGG41620.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Rhodanese PF00581.15 EGG41621.1 - 4.9e-44 149.2 0.1 1.4e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Ammonium_transp PF00909.16 EGG41622.1 - 1.7e-108 362.6 33.2 1.7e-108 362.6 23.0 1.9 2 1 0 2 2 2 1 Ammonium Transporter Family DUF334 PF03904.8 EGG41623.1 - 0.008 15.5 2.2 0.012 14.9 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF334) SAM_2 PF07647.12 EGG41623.1 - 0.05 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) vATP-synt_AC39 PF01992.11 EGG41624.1 - 2.9e-37 128.5 8.7 3.5e-37 128.3 6.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DNA_ligase_OB PF03120.11 EGG41624.1 - 0.027 14.1 0.1 8.2 6.1 0.0 3.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase OB-fold domain Fibritin_C PF07921.7 EGG41624.1 - 0.029 14.2 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Fibritin C-terminal region Mak16 PF04874.9 EGG41624.1 - 0.068 13.2 0.7 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Mak16 protein C-terminal region ABC2_membrane_4 PF12730.2 EGG41625.1 - 0.017 14.2 6.7 0.018 14.2 4.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein FUSC PF04632.7 EGG41625.1 - 0.41 9.0 3.3 0.47 8.8 2.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cas_Cas4 PF01930.12 EGG41626.1 - 1.7e-05 24.7 0.3 2.7e-05 24.1 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function DUF83 DDE_Tnp_1_6 PF13751.1 EGG41626.1 - 0.054 13.4 0.5 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Transposase DDE domain PDDEXK_1 PF12705.2 EGG41626.1 - 0.31 10.3 2.4 3 7.1 1.7 2.1 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Glyco_trans_1_2 PF13524.1 EGG41628.1 - 0.023 14.9 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 AA_kinase PF00696.23 EGG41629.1 - 6.9e-31 107.6 1.2 8.4e-31 107.3 0.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family HD PF01966.17 EGG41630.1 - 3.4e-17 62.5 0.2 7.4e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 EGG41630.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 HDOD domain Thymidylate_kin PF02223.12 EGG41631.1 - 9.9e-40 135.8 0.2 1.1e-39 135.7 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase Glyco_transf_4 PF13439.1 EGG41631.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase Family 4 SPOB_a PF14689.1 EGG41631.1 - 0.062 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain DnaJ_CXXCXGXG PF00684.14 EGG41632.1 - 0.1 12.6 11.9 0.69 9.9 0.1 2.4 1 1 1 2 2 2 0 DnaJ central domain Ribosomal_L33 PF00471.15 EGG41632.1 - 0.24 11.6 2.2 0.62 10.3 1.5 1.7 1 0 0 1 1 1 0 Ribosomal protein L33 ESPR PF13018.1 EGG41632.1 - 0.67 9.6 2.3 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system zf-nanos PF05741.8 EGG41632.1 - 0.95 9.4 10.0 1.8 8.5 4.8 2.3 2 1 0 2 2 2 0 Nanos RNA binding domain Antifungal_prot PF11402.3 EGG41632.1 - 1.4 9.1 11.5 8.8 6.6 7.6 2.2 1 1 0 1 1 1 0 Antifungal protein DZR PF12773.2 EGG41632.1 - 2.9 7.7 9.1 3.2 7.6 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF3268 PF11672.3 EGG41632.1 - 3.7 7.6 8.9 9.8 6.3 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) Prok-RING_2 PF14445.1 EGG41632.1 - 8 6.4 10.5 3.3 7.7 2.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 2 HSP20 PF00011.16 EGG41633.1 - 3.4e-13 49.3 0.2 4.4e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ABC1 PF03109.11 EGG41634.1 - 9.2e-23 80.4 0.0 3.2e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EGG41634.1 - 0.0084 15.8 0.0 0.033 13.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RRF_GI PF12614.3 EGG41635.1 - 0.15 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Multi_Drug_Res PF00893.14 EGG41636.1 - 0.0074 16.7 1.4 0.0082 16.5 1.0 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein GWT1 PF06423.7 EGG41636.1 - 0.017 15.2 0.2 0.017 15.1 0.1 1.0 1 0 0 1 1 1 0 GWT1 DUF2975 PF11188.3 EGG41636.1 - 0.037 13.7 1.3 0.038 13.6 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Class_IIIsignal PF04021.7 EGG41636.1 - 0.065 12.9 0.8 0.065 12.9 0.6 2.1 2 0 0 2 2 2 0 Class III signal peptide SdpI PF13630.1 EGG41636.1 - 0.09 12.4 1.7 0.11 12.2 1.2 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF3311 PF11755.3 EGG41636.1 - 0.091 12.3 0.1 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3311) Phageshock_PspG PF09583.5 EGG41636.1 - 0.11 12.6 0.3 0.11 12.6 0.2 1.6 2 0 0 2 2 2 0 Phage shock protein G (Phageshock_PspG) NPCBM_assoc PF10633.4 EGG41637.1 - 0.00086 19.3 0.9 0.66 10.0 0.0 3.7 3 2 1 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase ABC_tran PF00005.22 EGG41638.1 - 1.4e-19 70.7 0.0 2.1e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGG41638.1 - 6e-05 22.3 0.1 7.3e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGG41638.1 - 0.00015 21.8 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EGG41638.1 - 0.011 15.6 0.1 0.2 11.5 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NYN PF01936.13 EGG41638.1 - 0.013 15.7 0.3 0.045 14.0 0.2 1.7 1 1 0 1 1 1 0 NYN domain AviRa PF11599.3 EGG41638.1 - 0.028 13.4 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 RRNA methyltransferase AviRa AAA_13 PF13166.1 EGG41638.1 - 0.092 11.1 0.2 0.12 10.7 0.2 1.1 1 0 0 1 1 1 0 AAA domain MacB_PCD PF12704.2 EGG41639.1 - 4.9e-26 91.7 2.3 9.6e-26 90.7 1.6 1.5 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.16 EGG41639.1 - 3.6e-19 68.7 8.3 3.6e-19 68.7 5.7 1.9 2 0 0 2 2 2 1 FtsX-like permease family HTH_24 PF13412.1 EGG41640.1 - 3e-07 29.7 1.6 6.7e-07 28.6 1.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EGG41640.1 - 0.00018 20.9 0.1 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.17 EGG41640.1 - 0.00054 19.6 0.2 0.001 18.7 0.2 1.5 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 EGG41640.1 - 0.0027 17.3 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Trp_repressor PF01371.14 EGG41640.1 - 0.0096 15.8 0.3 0.035 14.0 0.1 2.0 2 0 0 2 2 2 1 Trp repressor protein HTH_Mga PF08280.6 EGG41640.1 - 0.0096 15.6 3.7 0.0096 15.6 2.6 2.8 3 0 0 3 3 3 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.7 EGG41640.1 - 0.012 15.2 0.9 0.032 13.8 0.3 2.0 2 0 0 2 2 2 0 HTH domain Mga PF05043.8 EGG41640.1 - 0.014 15.6 0.2 0.038 14.2 0.1 1.8 1 0 0 1 1 1 0 Mga helix-turn-helix domain DUF1366 PF07104.6 EGG41640.1 - 0.024 14.2 0.4 0.053 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) HTH_40 PF14493.1 EGG41640.1 - 0.035 14.3 0.3 0.095 12.9 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain PAH PF02671.16 EGG41640.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Paired amphipathic helix repeat HTH_36 PF13730.1 EGG41640.1 - 0.11 12.6 0.5 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain NUDIX PF00293.23 EGG41641.1 - 2.3e-18 66.1 0.0 2.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AF0941-like PF14591.1 EGG41641.1 - 0.0035 17.3 1.5 0.0066 16.4 0.4 1.8 1 1 0 1 1 1 1 AF0941-like PhoU PF01895.14 EGG41642.1 - 2.1e-10 40.9 4.9 9.8e-07 29.1 1.2 2.8 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 EGG41642.1 - 0.00028 20.5 0.0 0.00071 19.2 0.0 1.8 1 0 0 1 1 1 1 Antidote-toxin recognition MazE A2M_N_2 PF07703.9 EGG41642.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region GHMP_kinases_N PF00288.21 EGG41643.1 - 9.2e-12 44.8 0.1 1.6e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain PHP PF02811.14 EGG41643.1 - 0.0099 15.6 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 PHP domain Telomere_Sde2_2 PF13297.1 EGG41643.1 - 0.016 14.4 0.2 0.06 12.6 0.0 2.0 2 0 0 2 2 2 0 Telomere stability C-terminal DUF1884 PF08967.5 EGG41643.1 - 0.043 13.8 0.4 0.11 12.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1884) GHMP_kinases_C PF08544.8 EGG41643.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal DUF137 PF02006.11 EGG41644.1 - 2.5e-66 222.4 2.8 3e-66 222.1 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF137 Pantoate_transf PF02548.10 EGG41645.1 - 1e-108 362.4 2.4 1.1e-108 362.2 1.7 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EGG41645.1 - 0.00024 20.4 0.3 0.0015 17.8 0.2 2.2 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DFP PF04127.10 EGG41646.1 - 2.8e-59 199.8 4.6 6.3e-57 192.1 1.7 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.14 EGG41646.1 - 1.1e-27 96.2 0.4 1.1e-27 96.2 0.3 2.0 2 0 0 2 2 2 1 Flavoprotein NAD_binding_10 PF13460.1 EGG41646.1 - 0.0009 19.2 0.0 0.0061 16.5 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 EGG41646.1 - 0.0016 18.6 2.4 0.41 10.9 0.0 3.3 2 1 0 2 2 2 2 Putative NAD(P)-binding YjeF_N PF03853.10 EGG41646.1 - 0.0047 16.5 0.2 1.8 8.1 0.0 2.9 2 1 0 2 2 2 2 YjeF-related protein N-terminus Glyco_transf_4 PF13439.1 EGG41646.1 - 0.02 14.6 0.0 1.6 8.4 0.0 2.6 2 1 0 2 2 2 0 Glycosyltransferase Family 4 BRCT PF00533.21 EGG41646.1 - 0.027 14.6 0.4 0.17 12.0 0.0 2.5 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Pyr_redox PF00070.22 EGG41646.1 - 0.11 12.9 1.7 38 4.7 0.0 4.0 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 EGG41647.1 - 6.9e-20 71.1 0.0 9.7e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGG41647.1 - 2e-18 66.3 0.1 2e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGG41647.1 - 3e-15 56.4 0.0 6.1e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41647.1 - 2.8e-12 46.6 0.0 3.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41647.1 - 7.2e-12 45.8 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG41647.1 - 2.4e-11 43.9 0.0 4.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41647.1 - 3.3e-11 43.5 0.0 5.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG41647.1 - 2.3e-05 23.8 0.3 4.1e-05 23.0 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EGG41647.1 - 2.5e-05 23.4 0.0 3.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EGG41647.1 - 9.1e-05 22.0 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 EGG41647.1 - 0.00043 19.6 0.3 0.0017 17.6 0.1 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.6 EGG41647.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EGG41647.1 - 0.0043 17.0 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGG41647.1 - 0.0057 15.5 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.7 EGG41647.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 EGG41647.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Fibrillarin PF01269.12 EGG41647.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin CMAS PF02353.15 EGG41647.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGG41647.1 - 0.088 11.9 0.3 0.24 10.4 0.2 1.7 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3888 PF13027.1 EGG41648.1 - 0.2 11.5 3.0 0.35 10.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Peptidase_M24 PF00557.19 EGG41649.1 - 1.8e-54 184.5 0.0 2.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PGBA_N PF15436.1 EGG41649.1 - 0.0042 16.3 0.1 0.0096 15.2 0.0 1.7 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA N-terminal DUF4428 PF14471.1 EGG41649.1 - 0.23 11.2 3.4 0.32 10.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ThiI PF02568.9 EGG41650.1 - 5.2e-14 52.1 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EGG41650.1 - 7.8e-08 31.2 0.1 2e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase DUF814 PF05670.8 EGG41650.1 - 6.9e-07 29.0 0.0 2.1e-06 27.4 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF814) Asn_synthase PF00733.16 EGG41650.1 - 8.9e-05 22.1 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGG41650.1 - 0.0065 15.7 0.9 0.011 14.9 0.1 1.8 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC DUF552 PF04472.7 EGG41651.1 - 4.7e-15 55.2 0.6 5.3e-15 55.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF552) H_kinase_N PF12282.3 EGG41651.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal transduction histidine kinase Beta-Casp PF10996.3 EGG41652.1 - 9e-32 109.6 0.0 1.7e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EGG41652.1 - 3.2e-20 72.6 0.0 5.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EGG41652.1 - 7e-15 54.5 0.0 3e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGG41652.1 - 1.9e-11 43.8 0.0 6.8e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGG41652.1 - 0.006 16.2 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Proteasome PF00227.21 EGG41653.1 - 7.4e-38 129.7 0.0 8.5e-38 129.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Fe-ADH_2 PF13685.1 EGG41654.1 - 2.1e-68 230.3 1.2 2.1e-68 230.3 0.8 1.4 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EGG41654.1 - 1.4e-24 86.4 0.1 2e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EGG41654.1 - 1.9e-06 26.9 0.5 4.2e-05 22.6 0.3 2.6 1 1 0 1 1 1 1 3-dehydroquinate synthase AIRC PF00731.15 EGG41654.1 - 0.003 16.8 1.9 0.0078 15.5 0.2 2.2 2 0 0 2 2 2 1 AIR carboxylase FKBP_C PF00254.23 EGG41655.1 - 1.9e-12 47.0 0.6 1.2e-11 44.4 0.2 2.3 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aminotran_5 PF00266.14 EGG41656.1 - 3.5e-38 131.3 0.0 4.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGG41656.1 - 1.1e-05 23.9 0.8 1.6e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGG41656.1 - 0.0027 16.8 0.1 0.0053 15.9 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Lipoprotein_9 PF03180.9 EGG41656.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein CTP_transf_2 PF01467.21 EGG41657.1 - 8.2e-17 61.6 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Citrate_ly_lig PF08218.6 EGG41657.1 - 0.061 12.7 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain Thioredoxin_8 PF13905.1 EGG41657.1 - 0.078 13.1 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin-like RTC PF01137.16 EGG41658.1 - 2.7e-75 252.0 0.4 3.2e-75 251.8 0.3 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CopD PF05425.8 EGG41659.1 - 5.6e-16 58.6 0.2 5.6e-16 58.6 0.2 1.7 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.4 EGG41659.1 - 0.0018 18.0 5.7 0.0028 17.4 4.0 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) UPF0093 PF03653.8 EGG41659.1 - 0.0021 18.0 8.9 0.0068 16.3 6.2 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0093) 7TM_GPCR_Srv PF10323.4 EGG41659.1 - 0.0082 15.3 2.0 0.012 14.7 1.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF4149 PF13664.1 EGG41659.1 - 0.013 15.5 3.0 0.013 15.5 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Selenoprotein_S PF06936.6 EGG41659.1 - 0.06 12.8 0.2 0.085 12.3 0.2 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) SieB PF14163.1 EGG41659.1 - 0.13 11.7 9.9 2.2 7.8 0.1 2.6 2 1 0 2 2 2 0 Superinfection exclusion protein B Aa_trans PF01490.13 EGG41659.1 - 0.21 10.0 8.5 0.0074 14.8 2.0 1.5 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein YrhC PF14143.1 EGG41659.1 - 0.43 10.5 0.1 0.43 10.5 0.1 2.6 3 1 0 3 3 3 0 YrhC-like protein Brr6_like_C_C PF10104.4 EGG41659.1 - 2.7 7.4 9.1 0.12 11.8 1.9 2.0 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Usher PF00577.15 EGG41660.1 - 0.0013 17.5 0.0 0.0017 17.1 0.0 1.1 1 0 0 1 1 1 1 Outer membrane usher protein Lumazine_bd PF12870.2 EGG41660.1 - 0.025 14.6 0.3 0.058 13.4 0.1 1.6 2 0 0 2 2 2 0 Lumazine-binding domain DUF3426 PF11906.3 EGG41660.1 - 0.061 12.9 0.1 0.12 12.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3426) LEA_2 PF03168.8 EGG41660.1 - 0.065 13.6 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein Nitroreductase PF00881.19 EGG41661.1 - 7.6e-27 94.1 0.0 1.1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family FMN_red PF03358.10 EGG41662.1 - 9.9e-25 86.8 0.0 1.2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGG41662.1 - 1.7e-08 34.2 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF1297 PF06973.7 EGG41662.1 - 0.047 12.9 0.1 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1297) ABC_membrane PF00664.18 EGG41664.1 - 0.0027 17.1 0.2 0.0036 16.7 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Bap31 PF05529.7 EGG41664.1 - 0.0028 17.1 3.3 0.0028 17.1 2.3 1.4 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like ATG16 PF08614.6 EGG41664.1 - 0.003 17.4 11.7 0.0035 17.1 8.1 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) MLANA PF14991.1 EGG41664.1 - 0.0082 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein melan-A TBPIP PF07106.8 EGG41664.1 - 0.013 15.0 7.4 0.013 15.0 5.1 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vps53_N PF04100.7 EGG41664.1 - 0.015 14.0 7.2 0.018 13.8 5.0 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Troponin PF00992.15 EGG41664.1 - 0.046 13.7 6.0 0.063 13.3 4.1 1.1 1 0 0 1 1 1 0 Troponin DUF2730 PF10805.3 EGG41664.1 - 0.059 13.1 4.9 0.21 11.3 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) PFEMP PF03011.10 EGG41664.1 - 0.063 13.6 4.4 0.079 13.2 3.0 1.1 1 0 0 1 1 1 0 PFEMP DBL domain CheY-binding PF09078.6 EGG41664.1 - 0.12 12.4 3.1 0.97 9.4 0.4 2.9 1 1 2 3 3 3 0 CheY binding Allexi_40kDa PF05549.6 EGG41664.1 - 0.17 11.1 6.7 0.2 10.8 4.7 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein RmuC PF02646.11 EGG41664.1 - 0.23 10.2 9.0 0.08 11.7 4.0 1.7 1 1 1 2 2 2 0 RmuC family Seryl_tRNA_N PF02403.17 EGG41664.1 - 0.24 11.4 7.3 0.19 11.7 3.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 EGG41664.1 - 0.25 10.4 7.2 0.21 10.7 3.4 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGG41664.1 - 0.38 10.5 3.9 0.61 9.9 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EGG41664.1 - 0.68 9.4 11.3 0.8 9.2 7.8 1.4 1 1 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EGG41664.1 - 0.95 9.4 7.3 4.9 7.1 0.3 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EGG41664.1 - 1.5 8.9 8.9 1.5 8.9 5.5 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LRR_4 PF12799.2 EGG41664.1 - 1.7 8.3 5.2 54 3.5 3.6 3.0 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Ribosomal_L29 PF00831.18 EGG41664.1 - 3 7.5 8.1 3.1 7.5 1.8 2.6 1 1 1 2 2 2 0 Ribosomal L29 protein DivIC PF04977.10 EGG41664.1 - 9.4 5.8 8.5 9.2 5.8 2.1 2.9 1 1 2 3 3 3 0 Septum formation initiator Pro_isomerase PF00160.16 EGG41665.1 - 1.1e-50 171.8 0.1 1.2e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4064 PF13273.1 EGG41666.1 - 0.077 13.1 2.3 0.13 12.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1312 PF07009.6 EGG41666.1 - 0.69 9.7 10.9 0.28 11.0 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1312) Tap-RNA_bind PF09162.5 EGG41667.1 - 0.12 12.0 0.1 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Tap, RNA-binding LEA_2 PF03168.8 EGG41668.1 - 0.044 14.1 0.1 0.18 12.2 0.1 1.9 1 1 0 1 1 1 0 Late embryogenesis abundant protein PfkB PF00294.19 EGG41669.1 - 2.5e-23 82.6 0.2 7e-23 81.2 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGG41669.1 - 4.2e-06 26.1 0.0 7.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 EGG41669.1 - 0.0015 17.8 0.4 0.56 9.4 0.1 2.5 2 1 1 3 3 3 2 Carbohydrate kinase dUTPase_2 PF08761.6 EGG41670.1 - 4.6e-19 69.1 5.9 4.8e-14 52.7 0.1 2.0 1 1 1 2 2 2 2 dUTPase PRA-PH PF01503.12 EGG41670.1 - 0.02 15.1 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF550 PF04447.7 EGG41670.1 - 0.099 12.2 1.6 0.29 10.7 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF550) MtrA PF04208.9 EGG41671.1 - 5.9e-26 90.9 0.2 7.1e-26 90.7 0.2 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A FAINT PF04385.10 EGG41671.1 - 0.093 12.5 0.8 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, DUF529 DegT_DnrJ_EryC1 PF01041.12 EGG41672.1 - 9e-115 383.5 0.0 1e-114 383.4 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGG41672.1 - 1.5e-08 33.7 0.1 2.5e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGG41672.1 - 3.5e-08 32.8 0.1 5.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGG41672.1 - 5.6e-08 31.4 0.2 9.2e-08 30.7 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGG41672.1 - 4.2e-06 26.1 0.0 1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase ComK PF06338.6 EGG41672.1 - 0.021 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 ComK protein OKR_DC_1 PF01276.15 EGG41672.1 - 0.054 12.0 0.1 0.078 11.5 0.1 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pyridoxal_deC PF00282.14 EGG41672.1 - 0.099 11.0 0.0 0.19 10.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain PepSY_TM_2 PF13703.1 EGG41673.1 - 1.8 8.7 5.7 0.72 10.0 1.3 2.3 1 1 1 2 2 2 0 PepSY-associated TM helix zf-C2H2_4 PF13894.1 EGG41675.1 - 2e-07 30.8 3.7 0.0045 17.2 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG41675.1 - 2.7e-06 27.3 6.8 0.0083 16.4 0.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.7 EGG41675.1 - 0.00068 18.8 0.5 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EGG41675.1 - 0.0025 16.9 0.4 0.59 9.4 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2H2_6 PF13912.1 EGG41675.1 - 0.0063 16.3 2.0 0.0063 16.3 1.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger PHF5 PF03660.9 EGG41675.1 - 0.012 15.7 1.9 0.012 15.6 1.3 1.1 1 0 0 1 1 1 0 PHF5-like protein zf-FPG_IleRS PF06827.9 EGG41675.1 - 0.013 15.0 2.1 0.39 10.4 0.2 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Rubredoxin PF00301.15 EGG41675.1 - 0.017 14.9 0.6 2 8.3 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin DZR PF12773.2 EGG41675.1 - 0.018 14.8 4.2 0.018 14.8 2.9 1.5 1 1 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 EGG41675.1 - 0.023 14.3 4.7 0.47 10.1 3.3 2.2 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit Prok-RING_1 PF14446.1 EGG41675.1 - 0.028 14.1 6.3 0.78 9.5 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_5 PF13719.1 EGG41675.1 - 0.039 13.5 4.5 1.9 8.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG41675.1 - 0.043 13.5 4.2 1.7 8.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF678 PF05077.7 EGG41675.1 - 0.046 13.7 3.3 1.3 9.0 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF678) zinc_ribbon_2 PF13240.1 EGG41675.1 - 0.046 13.2 1.6 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37e PF01907.14 EGG41675.1 - 0.055 13.2 5.3 1.2 9.0 0.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e ADK_lid PF05191.9 EGG41675.1 - 0.06 13.0 2.9 3.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF1610 PF07754.6 EGG41675.1 - 0.077 13.1 1.1 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Ribosomal_S27e PF01667.12 EGG41675.1 - 0.11 12.0 3.8 0.15 11.6 0.3 2.1 1 1 1 2 2 2 0 Ribosomal protein S27 FYVE PF01363.16 EGG41675.1 - 0.12 12.2 7.4 0.36 10.7 1.4 2.0 1 1 1 2 2 2 0 FYVE zinc finger Zn-ribbon_8 PF09723.5 EGG41675.1 - 0.13 12.2 7.9 1.8 8.6 3.5 2.3 1 1 1 2 2 2 0 Zinc ribbon domain XPA_N PF01286.13 EGG41675.1 - 0.13 11.9 3.5 2.3 7.9 0.4 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_2 PF12756.2 EGG41675.1 - 0.23 11.5 6.6 1.1 9.3 1.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GCC2_GCC3 PF07699.8 EGG41675.1 - 0.25 10.9 10.1 0.1 12.1 2.0 2.1 1 1 1 2 2 2 0 GCC2 and GCC3 GFA PF04828.9 EGG41675.1 - 0.28 11.1 3.9 0.95 9.4 0.2 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.17 EGG41675.1 - 0.29 10.8 6.4 1.7 8.4 1.1 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rpr2 PF04032.11 EGG41675.1 - 0.35 10.7 5.3 1.1 9.2 3.7 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain A2L_zn_ribbon PF08792.5 EGG41675.1 - 0.48 9.9 2.7 7.8 6.0 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain PyrI_C PF02748.10 EGG41675.1 - 0.49 9.8 4.7 1.6 8.2 0.3 2.0 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Med27 PF11571.3 EGG41675.1 - 0.59 10.2 4.8 1.2 9.2 0.4 2.1 1 1 1 2 2 2 0 Mediator complex subunit 27 Synaptonemal_3 PF15191.1 EGG41675.1 - 0.76 9.5 4.1 1.2 8.8 0.5 2.0 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 Fer4 PF00037.22 EGG41675.1 - 0.84 9.3 4.7 10 5.9 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Rad50_zn_hook PF04423.9 EGG41675.1 - 1.1 8.7 7.5 4.1 6.9 1.7 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif HypA PF01155.14 EGG41675.1 - 1.5 8.5 6.6 2.5 7.8 3.2 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 EGG41675.1 - 1.7 9.0 10.0 1.9 8.9 1.3 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Auto_anti-p27 PF06677.7 EGG41675.1 - 2.1 8.1 5.0 0.93 9.3 0.2 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2_3 PF13878.1 EGG41675.1 - 2.3 7.8 10.2 5.5 6.6 1.0 2.5 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO YhfH PF14149.1 EGG41675.1 - 2.4 8.0 9.6 9.4 6.1 0.1 2.4 2 1 0 2 2 2 0 YhfH-like protein DUF3795 PF12675.2 EGG41675.1 - 3.4 7.9 9.5 4.1 7.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) OrfB_Zn_ribbon PF07282.6 EGG41675.1 - 3.4 7.3 7.2 7.9 6.2 4.3 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DM PF00751.13 EGG41675.1 - 4.2 6.9 11.6 0.88 9.1 2.3 2.3 2 1 0 2 2 2 0 DM DNA binding domain zf-BED PF02892.10 EGG41675.1 - 4.6 7.0 10.2 2.1 8.2 0.7 2.4 1 1 1 2 2 2 0 BED zinc finger zf-CHY PF05495.7 EGG41675.1 - 7.5 6.7 9.8 22 5.2 6.8 1.7 1 1 0 1 1 1 0 CHY zinc finger FeoC PF09012.5 EGG41676.1 - 9.5e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 FeoC like transcriptional regulator CtsR PF05848.6 EGG41676.1 - 0.024 14.5 0.5 0.031 14.2 0.4 1.2 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) HTH_45 PF14947.1 EGG41676.1 - 0.036 13.8 4.0 0.11 12.3 2.8 1.9 1 1 0 1 1 1 0 Winged helix-turn-helix MarR PF01047.17 EGG41676.1 - 0.09 12.4 0.2 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 MarR family DHQ_synthase PF01761.15 EGG41677.1 - 0.049 12.5 0.0 0.057 12.3 0.0 1.0 1 0 0 1 1 1 0 3-dehydroquinate synthase tRNA-synt_1b PF00579.20 EGG41678.1 - 2.8e-41 141.5 0.1 3.5e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TP_methylase PF00590.15 EGG41679.1 - 6.4e-28 97.8 0.0 7.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Lipoprotein_15 PF03640.10 EGG41680.1 - 0.0079 15.6 0.5 0.85 9.1 0.0 2.6 2 0 0 2 2 2 2 Secreted repeat of unknown function MEDS PF14417.1 EGG41680.1 - 0.043 12.8 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AA_kinase PF00696.23 EGG41681.1 - 2.1e-50 171.5 1.4 2.1e-50 171.5 1.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 EGG41681.1 - 5.9e-21 73.5 4.0 2.4e-10 39.6 0.1 2.7 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EGG41681.1 - 3.3e-18 64.9 9.2 3e-12 45.8 0.2 3.1 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.1 EGG41681.1 - 0.024 14.3 2.1 0.57 9.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain BCDHK_Adom3 PF10436.4 EGG41681.1 - 0.069 12.6 0.8 0.12 11.9 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PCNA_N PF00705.13 EGG41682.1 - 3.9e-20 71.6 0.1 6.9e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EGG41682.1 - 1.6e-17 63.6 0.7 2.2e-16 59.9 0.0 2.5 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EGG41682.1 - 0.0015 17.7 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Pox_A51 PF04948.8 EGG41682.1 - 0.033 12.8 0.2 0.044 12.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A51 protein Receptor_2B4 PF11465.3 EGG41682.1 - 0.11 12.3 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 TFIIS_C PF01096.13 EGG41683.1 - 9.9e-20 69.8 5.6 9.9e-20 69.8 3.9 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 EGG41683.1 - 8.5e-06 25.4 7.4 0.0046 16.7 1.3 2.3 2 0 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EGG41683.1 - 0.00024 20.8 9.6 0.0017 18.0 0.2 3.3 2 1 1 3 3 3 1 Transposase zinc-ribbon domain Elf1 PF05129.8 EGG41683.1 - 0.0066 16.1 5.7 0.058 13.0 0.3 2.3 1 1 1 2 2 2 1 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 EGG41683.1 - 0.0073 15.6 0.5 0.0073 15.6 0.4 2.3 1 1 1 2 2 2 1 DNA Polymerase alpha zinc finger Prok-RING_1 PF14446.1 EGG41683.1 - 0.012 15.3 2.1 0.012 15.3 1.4 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 RNA_POL_M_15KD PF02150.11 EGG41683.1 - 0.019 14.6 16.8 0.59 9.8 4.3 3.6 2 2 1 3 3 3 0 RNA polymerases M/15 Kd subunit zf-GRF PF06839.7 EGG41683.1 - 0.029 14.3 0.7 0.029 14.3 0.5 2.5 3 0 0 3 3 3 0 GRF zinc finger zinc_ribbon_5 PF13719.1 EGG41683.1 - 0.032 13.7 16.8 1 9.0 0.6 4.1 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG41683.1 - 0.042 13.5 16.7 0.79 9.4 0.5 4.1 3 1 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 EGG41683.1 - 0.054 13.4 8.9 4 7.5 0.1 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain zf-ribbon_3 PF13248.1 EGG41683.1 - 0.08 12.1 10.6 0.55 9.5 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 EGG41683.1 - 0.099 12.6 6.2 13 5.8 0.9 3.1 3 0 0 3 3 3 0 Ribosomal protein L44 zf-NADH-PPase PF09297.6 EGG41683.1 - 0.18 11.3 10.4 0.16 11.5 1.9 3.7 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 EGG41683.1 - 0.18 11.3 15.3 7.6 6.1 0.0 3.7 3 1 0 3 3 3 0 zinc-ribbon domain C1_2 PF03107.11 EGG41683.1 - 0.26 11.4 0.4 0.26 11.4 0.3 2.8 4 0 0 4 4 3 0 C1 domain A2L_zn_ribbon PF08792.5 EGG41683.1 - 0.28 10.6 11.8 1.2 8.6 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain Baculo_LEF5_C PF11792.3 EGG41683.1 - 0.33 10.3 0.1 0.33 10.3 0.1 3.1 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.5 EGG41683.1 - 0.41 10.6 14.9 5.1 7.1 0.0 4.2 3 1 0 3 3 3 0 Zinc ribbon domain C1_1 PF00130.17 EGG41683.1 - 0.42 10.3 9.2 1.3 8.8 0.9 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYND PF01753.13 EGG41683.1 - 0.54 10.1 9.7 0.57 10.1 0.6 2.4 2 0 0 2 2 2 0 MYND finger zinc-ribbons_6 PF07191.7 EGG41683.1 - 0.77 9.5 11.6 0.051 13.3 1.3 2.9 1 1 1 3 3 3 0 zinc-ribbons HypA PF01155.14 EGG41683.1 - 0.89 9.2 12.4 0.34 10.6 1.7 2.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EGG41683.1 - 0.99 9.1 12.4 0.49 10.0 1.0 3.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-H2C2_5 PF13909.1 EGG41683.1 - 2 8.8 0.1 2 8.8 0.1 3.1 4 0 0 4 4 2 0 C2H2-type zinc-finger domain zf-C4pol PF14260.1 EGG41683.1 - 2 8.4 7.6 3.3 7.7 2.8 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-H2C2_2 PF13465.1 EGG41683.1 - 3 8.3 16.5 5.7 7.4 0.6 4.0 3 1 1 4 4 4 0 Zinc-finger double domain DUF3795 PF12675.2 EGG41683.1 - 3.2 7.9 10.7 0.76 9.9 4.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zf-C4_Topoisom PF01396.14 EGG41683.1 - 3.4 7.2 13.9 6.4 6.3 2.2 3.7 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger IBR PF01485.16 EGG41683.1 - 4.3 7.2 13.0 59 3.6 6.3 2.9 2 1 0 2 2 2 0 IBR domain zf-Mss51 PF13824.1 EGG41683.1 - 4.4 7.2 10.2 7.5 6.4 1.6 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.1 EGG41683.1 - 6.8 7.0 12.7 9 6.6 5.2 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-AN1 PF01428.11 EGG41683.1 - 7.2 6.5 9.9 13 5.7 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger Zn_Tnp_IS1 PF03811.8 EGG41683.1 - 8.3 5.9 18.7 10 5.7 3.7 4.0 2 2 1 3 3 3 0 InsA N-terminal domain RNA_pol_L_2 PF13656.1 EGG41684.1 - 1.7e-17 62.5 0.2 2e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DSPc PF00782.15 EGG41688.1 - 1.7e-17 63.2 0.0 2.2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG41688.1 - 2.2e-09 37.0 0.2 1.3e-08 34.5 0.0 1.8 1 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGG41688.1 - 2.4e-07 30.9 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 EGG41688.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EGG41688.1 - 0.0064 16.7 0.1 0.012 15.8 0.1 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Rep_trans PF02486.14 EGG41688.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Replication initiation factor Y_phosphatase2 PF03162.8 EGG41688.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family Radical_SAM PF04055.16 EGG41689.1 - 3.5e-13 50.0 0.2 1.5e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EGG41689.1 - 0.0022 18.0 2.0 0.0025 17.9 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain DUF3419 PF11899.3 EGG41689.1 - 0.0093 14.7 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) RadC PF04002.10 EGG41689.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain zf-FCS PF06467.9 EGG41689.1 - 1.3 8.7 16.8 0.22 11.1 0.7 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Cyclase PF04199.8 EGG41690.1 - 6.3e-33 113.8 0.0 7.7e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase AsnC_trans_reg PF01037.16 EGG41691.1 - 5.5e-08 32.4 0.1 5.9e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 AsnC family Aminotran_5 PF00266.14 EGG41692.1 - 7.3e-71 238.8 0.0 8.4e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGG41692.1 - 2.5e-07 29.9 0.0 3.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II YgbB PF02542.11 EGG41692.1 - 0.018 14.8 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 YgbB family EF-hand_1 PF00036.27 EGG41692.1 - 0.044 13.0 0.5 0.1 11.9 0.4 1.6 1 0 0 1 1 1 0 EF hand PYRIN PF02758.11 EGG41692.1 - 0.15 11.7 1.1 0.81 9.4 0.1 2.3 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Elong_Iki1 PF10483.4 EGG41693.1 - 0.052 12.9 0.1 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 Fer4 PF00037.22 EGG41694.1 - 1.7e-11 43.2 10.5 4.3e-07 29.2 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGG41694.1 - 1e-09 38.6 3.7 1.5e-09 38.1 2.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGG41694.1 - 1.6e-09 37.2 8.6 3.7e-05 23.4 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 EGG41694.1 - 9.5e-08 31.7 3.3 1.6e-07 31.0 2.3 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGG41694.1 - 9.7e-08 31.7 1.6 1.4e-07 31.2 1.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGG41694.1 - 2.6e-07 30.1 8.9 0.0032 17.2 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EGG41694.1 - 1.6e-05 25.0 8.2 0.00017 21.7 5.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 EGG41694.1 - 1.8e-05 24.7 7.8 0.03 14.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 EGG41694.1 - 6.3e-05 23.6 1.0 0.17 12.6 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 EGG41694.1 - 7.7e-05 22.9 12.3 0.043 14.3 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 EGG41694.1 - 8.6e-05 22.8 5.2 0.14 12.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_8 PF13183.1 EGG41694.1 - 0.0002 21.3 3.9 0.00055 19.9 2.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 EGG41694.1 - 0.00024 21.5 9.6 0.012 16.1 0.7 2.7 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 EGG41694.1 - 0.00057 20.2 6.2 0.041 14.3 1.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EGG41694.1 - 0.0026 18.0 5.6 0.056 13.7 3.8 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Copper-bind PF00127.15 EGG41695.1 - 2.1e-07 31.0 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EGG41695.1 - 0.078 12.8 0.0 0.97 9.3 0.0 2.9 4 1 0 4 4 4 0 Cupredoxin-like domain P-II PF00543.17 EGG41696.1 - 2.1e-19 69.8 4.7 2.5e-19 69.6 3.2 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II HAMP PF00672.20 EGG41697.1 - 2e-16 59.8 0.4 5.5e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 HAMP domain Guanylate_cyc PF00211.15 EGG41697.1 - 6.3e-13 48.4 0.1 1.7e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DnaJ PF00226.26 EGG41698.1 - 2.2e-12 46.5 0.0 4.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Usp PF00582.21 EGG41699.1 - 1.2e-30 106.5 0.0 1.5e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family GARS_N PF02844.10 EGG41699.1 - 0.058 13.8 0.0 13 6.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain DUF3880 PF12996.2 EGG41699.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) CBS PF00571.23 EGG41700.1 - 1.6e-47 159.0 3.5 1.5e-13 50.2 0.1 4.1 4 0 0 4 4 4 4 CBS domain Sigma54_DBD PF04552.8 EGG41700.1 - 0.023 14.2 0.1 0.054 13.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54, DNA binding domain Ldh_1_C PF02866.13 EGG41701.1 - 2.4e-26 92.5 0.7 2.2e-25 89.4 0.1 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGG41701.1 - 7.6e-24 84.1 1.4 1.4e-23 83.2 1.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 EGG41701.1 - 6.4e-07 28.8 0.5 3e-06 26.6 0.1 2.2 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Shikimate_DH PF01488.15 EGG41701.1 - 3e-05 24.1 0.3 6.9e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGG41701.1 - 0.00047 19.9 0.4 0.0017 18.1 0.3 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EGG41701.1 - 0.019 15.3 0.3 0.055 13.9 0.2 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HTH_IclR PF09339.5 EGG41702.1 - 4.9e-05 22.8 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.2 EGG41702.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 EGG41702.1 - 0.00023 20.8 0.1 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.6 EGG41702.1 - 0.0067 16.0 0.0 0.0084 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF742) FUR PF01475.14 EGG41702.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family DND1_DSRM PF14709.1 EGG41702.1 - 0.037 14.3 0.1 0.086 13.1 0.0 1.6 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Hpr_kinase_N PF02603.11 EGG41702.1 - 0.044 13.4 0.1 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 HPr Serine kinase N terminus HTH_Tnp_ISL3 PF13542.1 EGG41702.1 - 0.049 12.8 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.15 EGG41702.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 EGG41702.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 EGG41702.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain CBS PF00571.23 EGG41703.1 - 1e-47 159.6 6.0 5.6e-16 58.0 0.1 4.1 4 0 0 4 4 4 4 CBS domain IF3_N PF05198.11 EGG41703.1 - 0.065 13.1 0.8 23 4.9 0.0 3.3 3 1 0 3 3 3 0 Translation initiation factor IF-3, N-terminal domain AA_permease_2 PF13520.1 EGG41704.1 - 9.3e-52 175.9 60.8 1.3e-51 175.4 42.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGG41704.1 - 1.9e-45 155.0 54.8 2.9e-45 154.5 38.0 1.3 1 1 0 1 1 1 1 Amino acid permease Chordopox_A13L PF05961.6 EGG41704.1 - 0.06 13.2 0.0 0.06 13.2 0.0 3.4 4 0 0 4 4 4 0 Chordopoxvirus A13L protein DUF962 PF06127.6 EGG41704.1 - 0.093 12.6 1.6 1.9 8.4 0.2 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Na_Ca_ex PF01699.19 EGG41705.1 - 6.8e-41 139.1 37.8 8.4e-26 90.2 10.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RIC3 PF15361.1 EGG41705.1 - 0.13 12.5 0.1 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF788 PF05620.6 EGG41705.1 - 8.8 6.1 11.3 0.95 9.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Usp PF00582.21 EGG41706.1 - 3e-28 98.7 0.2 3.3e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Universal stress protein family Pribosyltran PF00156.22 EGG41708.1 - 5.3e-18 64.9 0.4 9.1e-18 64.1 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 EGG41708.1 - 1.6e-14 54.0 1.2 1.1e-12 48.1 0.1 2.8 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.1 EGG41708.1 - 5.7e-05 22.4 0.1 0.00011 21.4 0.0 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Pribosyltran_N PF13793.1 EGG41708.1 - 0.00099 18.8 0.0 0.0031 17.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase PRTase_2 PF15609.1 EGG41708.1 - 0.0012 18.1 0.1 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase UPF0020 PF01170.13 EGG41709.1 - 3.3e-26 91.9 0.0 6.4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EGG41709.1 - 3.7e-16 59.2 0.0 5.7e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EGG41709.1 - 5.5e-13 48.9 0.0 1e-11 44.7 0.0 2.2 2 1 0 2 2 2 1 DNA methylase Methyltransf_31 PF13847.1 EGG41709.1 - 9e-12 44.8 0.2 2.2e-11 43.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGG41709.1 - 7.2e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EGG41709.1 - 8.1e-06 26.1 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41709.1 - 1.1e-05 26.0 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGG41709.1 - 0.00017 21.2 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein N6_Mtase PF02384.11 EGG41709.1 - 0.00022 20.4 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.7 EGG41709.1 - 0.00036 20.9 0.0 0.00066 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGG41709.1 - 0.00037 20.0 0.0 0.00077 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase THUMP PF02926.12 EGG41709.1 - 0.0004 20.2 0.1 0.00097 19.0 0.1 1.8 1 1 0 1 1 1 1 THUMP domain Methyltransf_5 PF01795.14 EGG41709.1 - 0.00062 19.1 0.1 0.0012 18.1 0.0 1.4 1 1 0 1 1 1 1 MraW methylase family PrmA PF06325.8 EGG41709.1 - 0.0017 17.5 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGG41709.1 - 0.0019 17.3 0.0 0.0037 16.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGG41709.1 - 0.0052 15.8 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MethyltransfD12 PF02086.10 EGG41709.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF43 PF01861.11 EGG41709.1 - 0.033 13.1 0.1 0.6 9.0 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EGG41709.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain EGL-1 PF11430.3 EGG41709.1 - 3.9 7.1 5.0 40 3.9 0.0 3.0 3 0 0 3 3 3 0 Programmed cell death activator EGL-1 Lactamase_B_2 PF12706.2 EGG41710.1 - 2.2e-25 89.3 0.0 3.1e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGG41710.1 - 1.5e-08 34.5 0.0 3.1e-07 30.2 0.0 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EGG41710.1 - 0.00052 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease SIR2 PF02146.12 EGG41711.1 - 4.2e-53 179.7 0.0 5.2e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EGG41711.1 - 0.00038 20.2 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain RNA_binding PF01877.12 EGG41712.1 - 7.4e-18 64.6 0.2 1.7e-17 63.4 0.1 1.5 1 1 0 1 1 1 1 RNA binding tRNA-synt_1g PF09334.6 EGG41712.1 - 0.0022 16.6 0.0 0.0025 16.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) AAA_18 PF13238.1 EGG41713.1 - 6.5e-11 42.6 0.1 1e-10 41.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG41713.1 - 8.1e-08 33.1 0.0 1.2e-07 32.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG41713.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EGG41713.1 - 0.063 13.1 0.1 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase LigT_PEase PF02834.11 EGG41714.1 - 2.5e-23 81.8 0.0 3.7e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.4 EGG41714.1 - 1.7e-14 54.0 0.2 2.4e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EGG41714.1 - 3.6e-08 33.2 0.0 4.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily tRNA_NucTransf2 PF09249.6 EGG41715.1 - 1.7e-39 134.2 0.1 3.8e-39 133.0 0.0 1.7 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.18 EGG41715.1 - 5.2e-08 33.1 0.2 1.5e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 EGG41716.1 - 3.3e-05 23.1 0.6 5.1e-05 22.5 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGG41716.1 - 9.7e-05 21.7 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EGG41716.1 - 0.00024 20.7 0.1 0.048 13.2 0.0 3.0 3 1 0 4 4 4 2 Choline/ethanolamine kinase Pyr_redox_2 PF07992.9 EGG41718.1 - 0.00022 21.1 0.0 0.00058 19.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGG41719.1 - 2.9e-11 43.6 0.0 3.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG41719.1 - 0.00018 21.4 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGG41719.1 - 0.00025 20.8 0.0 0.0043 16.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGG41719.1 - 0.00095 19.5 1.0 0.044 14.1 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG41719.1 - 0.0012 17.8 0.0 0.055 12.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGG41719.1 - 0.006 15.2 0.0 0.0067 15.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGG41719.1 - 0.088 12.8 0.0 4.3 7.3 0.1 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGG41719.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EGG41720.1 - 1.1e-35 123.0 0.1 1.8e-35 122.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG41720.1 - 1.3e-20 74.2 1.3 1.7e-20 73.8 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG41720.1 - 6.6e-14 51.9 0.0 1.1e-13 51.2 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGG41720.1 - 0.0001 22.3 1.5 0.00051 20.1 1.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGG41720.1 - 0.00012 21.6 0.3 0.0095 15.3 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGG41720.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 EGG41720.1 - 0.0065 15.5 3.2 0.085 11.9 0.0 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EGG41720.1 - 0.0094 15.7 4.4 0.0099 15.6 1.9 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BRCT PF00533.21 EGG41720.1 - 0.092 12.9 0.1 0.24 11.5 0.1 2.0 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-AN1 PF01428.11 EGG41721.1 - 3.7e-13 49.0 6.0 4.9e-13 48.7 4.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger UPF1_Zn_bind PF09416.5 EGG41721.1 - 0.046 13.3 1.3 0.053 13.0 0.9 1.2 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) zf-BED PF02892.10 EGG41721.1 - 0.33 10.7 1.9 4.8 7.0 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger Transp_Tc5_C PF04236.10 EGG41721.1 - 1.3 9.3 5.0 5.8 7.2 3.5 2.0 1 1 0 1 1 1 0 Tc5 transposase C-terminal domain zf-B_box PF00643.19 EGG41721.1 - 6.2 6.8 8.8 11 6.0 6.1 1.5 1 1 0 1 1 1 0 B-box zinc finger PyrI_C PF02748.10 EGG41721.1 - 6.3 6.3 7.4 5.7 6.4 0.5 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-HIT PF04438.11 EGG41721.1 - 7.1 6.3 7.9 1.4 8.6 3.2 1.6 2 0 0 2 2 2 0 HIT zinc finger CLN6 PF15156.1 EGG41722.1 - 0.012 14.7 0.5 0.014 14.5 0.3 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 B12D PF06522.6 EGG41722.1 - 0.047 13.3 0.4 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit EmrE PF13536.1 EGG41722.1 - 3.8 7.7 7.4 5.8 7.1 5.1 1.4 1 1 0 1 1 1 0 Multidrug resistance efflux transporter DUF3083 PF11281.3 EGG41723.1 - 0.045 12.8 0.7 0.072 12.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Fcf2 PF08698.6 EGG41723.1 - 0.068 13.2 0.8 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing Staygreen PF12638.2 EGG41723.1 - 0.083 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Staygreen protein Rhabdo_M1 PF03342.8 EGG41723.1 - 0.1 11.7 1.9 0.17 11.0 1.3 1.5 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Herpes_UL35 PF04496.7 EGG41723.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL35 family Peptidase_A3 PF02160.10 EGG41723.1 - 0.15 11.6 4.6 0.22 11.0 0.6 2.4 1 1 1 2 2 2 0 Cauliflower mosaic virus peptidase (A3) Gln-synt_C PF00120.19 EGG41724.1 - 9.6e-88 293.6 0.0 1.2e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGG41724.1 - 2.1e-16 59.2 0.0 4.7e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Bax1-I PF01027.15 EGG41725.1 - 0.00088 18.9 10.7 0.00095 18.8 7.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2628 PF10947.3 EGG41725.1 - 0.16 11.7 3.3 0.26 11.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) TMEM238 PF15125.1 EGG41725.1 - 0.59 10.0 4.3 0.11 12.3 0.6 1.5 2 0 0 2 2 2 0 TMEM238 protein family Cpn60_TCP1 PF00118.19 EGG41726.1 - 2.8e-169 563.7 18.7 3.2e-169 563.6 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ustilago_mating PF05722.7 EGG41726.1 - 0.04 13.2 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 Ustilago B locus mating-type protein SHMT PF00464.14 EGG41727.1 - 2e-77 260.2 0.0 2.9e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EGG41727.1 - 1.3e-07 30.8 0.0 9e-07 28.1 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG41727.1 - 5.2e-05 22.5 0.0 0.00011 21.4 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 EGG41727.1 - 0.004 15.9 0.0 0.0064 15.2 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_5 PF00266.14 EGG41727.1 - 0.0058 15.4 0.1 0.0093 14.7 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 EGG41727.1 - 0.0081 14.6 0.0 0.021 13.2 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain PolC_DP2 PF03833.8 EGG41728.1 - 5.6e-266 884.6 0.2 2.4e-265 882.6 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase II large subunit DP2 PcrB PF01884.12 EGG41729.1 - 5.2e-65 218.9 0.2 6.2e-65 218.6 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.16 EGG41729.1 - 6.5e-08 32.1 0.2 3.4e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.20 EGG41729.1 - 6.9e-06 25.1 0.2 2.2e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.15 EGG41729.1 - 0.0021 16.6 1.4 0.0089 14.5 0.2 2.3 2 1 1 3 3 3 1 Tryptophan synthase alpha chain ThiG PF05690.9 EGG41729.1 - 0.0031 16.6 0.8 0.3 10.1 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IGPS PF00218.16 EGG41729.1 - 0.0082 15.2 0.2 0.29 10.1 0.0 2.6 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Ribul_P_3_epim PF00834.14 EGG41729.1 - 0.022 13.8 0.2 0.085 11.9 0.0 1.8 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 EGG41729.1 - 0.041 12.9 0.1 0.75 8.8 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 EGG41729.1 - 0.05 12.5 1.3 0.052 12.5 0.2 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DeoC PF01791.4 EGG41729.1 - 0.092 12.0 0.7 0.19 11.0 0.2 1.6 2 0 0 2 2 2 0 DeoC/LacD family aldolase NMO PF03060.10 EGG41729.1 - 0.14 11.2 2.1 0.77 8.8 0.2 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase FliH PF02108.11 EGG41730.1 - 0.036 13.9 0.3 0.088 12.6 0.0 1.7 2 1 0 2 2 2 0 Flagellar assembly protein FliH G-alpha PF00503.15 EGG41730.1 - 0.09 11.4 0.4 0.14 10.8 0.3 1.3 1 0 0 1 1 1 0 G-protein alpha subunit HTH_27 PF13463.1 EGG41731.1 - 1.4e-06 28.4 0.1 2.5e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 EGG41731.1 - 1.8e-05 24.3 0.1 4.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 EGG41731.1 - 0.00081 19.3 1.1 0.0015 18.5 0.2 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain DUF3116 PF11313.3 EGG41731.1 - 0.0011 18.4 1.1 0.0026 17.3 0.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3116) Replic_Relax PF13814.1 EGG41731.1 - 0.0048 16.7 0.4 0.0089 15.8 0.1 1.5 2 0 0 2 2 2 1 Replication-relaxation MarR PF01047.17 EGG41731.1 - 0.0069 16.0 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.1 EGG41731.1 - 0.014 15.1 2.4 0.025 14.4 0.3 2.3 2 1 1 3 3 3 0 Winged helix-turn-helix pRN1_helical PF13010.1 EGG41731.1 - 0.017 14.7 0.3 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Primase helical domain IncA PF04156.9 EGG41731.1 - 0.023 14.2 0.4 0.034 13.7 0.3 1.2 1 0 0 1 1 1 0 IncA protein HTH_24 PF13412.1 EGG41731.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EGG41731.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family Antitoxin-MazE PF04014.13 EGG41732.1 - 1.9e-07 30.6 0.3 2.3e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 Antidote-toxin recognition MazE MraZ PF02381.13 EGG41732.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 MraZ protein Penicillinase_R PF03965.11 EGG41733.1 - 0.0032 17.5 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Penicillinase repressor Cdc6_C PF09079.6 EGG41734.1 - 2.9e-19 68.5 1.5 7.7e-19 67.2 0.5 2.1 2 0 0 2 2 2 1 CDC6, C terminal AAA PF00004.24 EGG41734.1 - 1.1e-11 45.0 1.1 5.6e-11 42.7 0.2 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG41734.1 - 1.4e-11 44.6 0.0 3.3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG41734.1 - 3.2e-09 37.0 0.1 2.9e-08 33.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EGG41734.1 - 5.8e-07 29.3 0.0 8.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EGG41734.1 - 1.7e-06 27.8 2.1 8.3e-06 25.6 1.5 2.1 1 1 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EGG41734.1 - 8.4e-05 21.7 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EGG41734.1 - 0.00022 20.2 0.1 0.00052 19.0 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase KAP_NTPase PF07693.9 EGG41734.1 - 0.00027 20.0 0.2 0.53 9.2 0.0 2.4 2 0 0 2 2 2 2 KAP family P-loop domain NB-ARC PF00931.17 EGG41734.1 - 0.00029 19.8 0.1 0.00055 18.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.9 EGG41734.1 - 0.00033 20.4 0.1 0.0011 18.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EGG41734.1 - 0.00067 18.6 0.0 0.0016 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_32 PF13654.1 EGG41734.1 - 0.0011 17.7 0.5 0.052 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EGG41734.1 - 0.0014 17.8 0.6 0.35 9.9 0.0 2.6 2 1 0 2 2 2 1 KaiC RNA_helicase PF00910.17 EGG41734.1 - 0.0029 17.7 0.0 0.008 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase T2SE PF00437.15 EGG41734.1 - 0.0032 16.4 0.0 0.0074 15.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EGG41734.1 - 0.0032 17.1 0.0 0.0084 15.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 EGG41734.1 - 0.006 15.2 0.0 0.018 13.6 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 EGG41734.1 - 0.0069 15.9 0.0 0.019 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGG41734.1 - 0.025 14.1 1.7 0.076 12.5 1.2 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGG41734.1 - 0.025 14.2 2.4 0.54 9.9 1.7 2.4 1 1 0 1 1 1 0 NTPase Mg_chelatase PF01078.16 EGG41734.1 - 0.028 13.5 0.0 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EGG41734.1 - 0.036 13.9 0.1 0.42 10.4 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DNA_pol_E_B PF04042.11 EGG41735.1 - 6.4e-22 77.8 0.0 1.1e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 EGG41735.1 - 6e-11 42.4 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGG41735.1 - 5.1e-07 29.2 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2326 PF10088.4 EGG41735.1 - 0.029 14.0 0.9 0.062 12.9 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) tRNA_anti-codon PF01336.20 EGG41735.1 - 0.033 14.0 0.1 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF95 PF01944.12 EGG41736.1 - 7.9e-09 35.3 7.9 9.6e-09 35.1 5.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF95 Copper-bind PF00127.15 EGG41737.1 - 0.043 14.0 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family TP_methylase PF00590.15 EGG41738.1 - 8.3e-38 130.2 0.0 9.3e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases bPH_3 PF14470.1 EGG41739.1 - 0.00073 19.7 0.5 0.069 13.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial PH domain DUF460 PF04312.8 EGG41741.1 - 0.00055 19.4 0.1 0.00077 19.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF460) UPF0081 PF03652.10 EGG41741.1 - 0.028 14.5 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0081) DivIVA PF05103.8 EGG41742.1 - 0.0012 18.8 6.1 0.0017 18.4 4.3 1.2 1 0 0 1 1 1 1 DivIVA protein MitMem_reg PF13012.1 EGG41742.1 - 0.0056 16.7 3.9 0.0086 16.1 2.7 1.4 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function TMCO5 PF14992.1 EGG41742.1 - 0.0089 15.1 6.0 0.0099 15.0 4.1 1.0 1 0 0 1 1 1 1 TMCO5 family HAUS2 PF15003.1 EGG41742.1 - 0.011 14.8 0.7 0.013 14.6 0.5 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Apolipoprotein PF01442.13 EGG41742.1 - 0.011 15.2 1.5 0.017 14.6 1.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Muted PF14942.1 EGG41742.1 - 0.018 14.9 3.0 0.024 14.5 2.1 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ATP-synt_B PF00430.13 EGG41742.1 - 0.023 14.5 7.1 0.038 13.7 4.4 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) COG6 PF06419.6 EGG41742.1 - 0.024 12.7 4.8 0.029 12.5 3.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Peptidase_C12 PF01088.16 EGG41742.1 - 0.029 13.5 1.2 0.036 13.2 0.9 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 CsoSCA PF08936.5 EGG41742.1 - 0.031 12.6 0.9 0.035 12.4 0.6 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase DUF948 PF06103.6 EGG41742.1 - 0.042 13.7 4.7 0.089 12.6 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 EGG41742.1 - 0.043 14.0 4.6 1 9.6 3.2 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TFIIA_gamma_N PF02268.11 EGG41742.1 - 0.061 12.9 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF972 PF06156.8 EGG41742.1 - 0.076 13.3 5.9 0.12 12.7 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) V-ATPase_G PF03179.10 EGG41742.1 - 0.077 13.2 7.3 0.12 12.7 5.1 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit CHASE3 PF05227.8 EGG41742.1 - 0.08 12.6 1.8 0.21 11.2 1.3 1.5 1 1 1 2 2 2 0 CHASE3 domain CorA PF01544.13 EGG41742.1 - 0.089 11.8 0.8 0.094 11.7 0.6 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mitofilin PF09731.4 EGG41742.1 - 0.13 10.9 8.9 0.15 10.6 6.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Baculo_PEP_C PF04513.7 EGG41742.1 - 0.14 11.9 3.8 0.22 11.3 0.5 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF848 PF05852.6 EGG41742.1 - 0.18 11.6 5.9 0.45 10.3 4.1 1.6 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Peptidase_M4 PF01447.13 EGG41742.1 - 0.2 11.7 1.2 0.23 11.5 0.8 1.1 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Syntaxin_2 PF14523.1 EGG41742.1 - 0.22 11.5 6.8 0.39 10.7 4.7 1.5 1 1 0 1 1 1 0 Syntaxin-like protein SMAP PF15477.1 EGG41742.1 - 0.38 11.0 2.2 0.72 10.1 1.5 1.6 1 1 0 1 1 1 0 Small acidic protein family Sox_N PF12444.3 EGG41742.1 - 0.39 11.8 1.6 0.58 11.2 1.1 1.6 1 1 0 1 1 1 0 Sox developmental protein N terminal Phasin PF05597.6 EGG41742.1 - 0.53 10.0 6.9 2.6 7.8 2.6 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.8 EGG41742.1 - 0.72 10.2 3.2 6.1 7.3 1.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Spc24 PF08286.6 EGG41742.1 - 1.1 9.0 7.4 9.2 5.9 5.1 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 EGG41742.1 - 1.4 8.8 4.4 3.5 7.6 0.6 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Pup PF05639.6 EGG41742.1 - 1.4 9.4 4.2 20 5.7 0.3 2.3 1 1 1 2 2 2 0 Pup-like protein NAC PF01849.13 EGG41743.1 - 1.2e-15 56.7 1.8 2.3e-15 55.8 1.3 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EGG41743.1 - 9.8e-06 25.2 0.2 9.8e-06 25.2 0.1 1.7 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EGG41743.1 - 0.0098 15.4 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 UBA-like domain Cytidylate_kin2 PF13189.1 EGG41743.1 - 0.094 12.6 0.9 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family ATP-synt_DE PF00401.15 EGG41743.1 - 0.21 11.4 2.0 0.37 10.6 1.4 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PUA PF01472.15 EGG41744.1 - 4.3e-10 39.1 0.0 1.1e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 PUA domain TGT_C2 PF14810.1 EGG41744.1 - 2.8e-09 36.7 0.0 4.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PhoU PF01895.14 EGG41745.1 - 1.5e-27 95.8 15.9 7.4e-19 67.9 1.9 2.5 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 EGG41745.1 - 5.1e-08 32.4 0.1 1.9e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Antidote-toxin recognition MazE Methyltransf_31 PF13847.1 EGG41746.1 - 9.1e-19 67.5 0.2 1.2e-18 67.1 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG41746.1 - 5.8e-17 61.9 0.0 8.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41746.1 - 4.5e-15 56.1 0.0 7.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41746.1 - 5e-15 55.7 0.2 9.2e-15 54.9 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41746.1 - 2.4e-14 53.3 0.0 2.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG41746.1 - 2.6e-10 40.5 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EGG41746.1 - 1e-09 38.1 0.0 1.1e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 EGG41746.1 - 9.1e-09 34.7 0.1 1.1e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 EGG41746.1 - 1.8e-08 33.8 0.0 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGG41746.1 - 1.3e-07 31.1 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGG41746.1 - 6.8e-06 25.3 0.0 8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EGG41746.1 - 4e-05 22.9 0.8 0.021 14.1 0.2 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 EGG41746.1 - 0.00027 20.9 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGG41746.1 - 0.012 15.0 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.8 EGG41746.1 - 0.022 13.8 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 EGG41746.1 - 0.024 13.3 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 EGG41746.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GidB PF02527.10 EGG41746.1 - 0.056 12.5 0.1 0.39 9.8 0.1 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 EGG41746.1 - 0.067 12.2 0.1 3.2 6.7 0.0 2.1 1 1 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EGG41746.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase UDPG_MGDP_dh_N PF03721.9 EGG41746.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mur_ligase PF01225.20 EGG41746.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Mur ligase family, catalytic domain MMR_HSR1 PF01926.18 EGG41747.1 - 1.5e-17 63.6 0.5 7.5e-17 61.3 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 EGG41747.1 - 1.9e-10 40.7 0.2 8.5e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal FeoB_N PF02421.13 EGG41747.1 - 7.5e-09 35.0 1.4 7.9e-09 34.9 0.3 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGG41747.1 - 7.7e-06 25.4 4.0 0.00069 19.0 2.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGG41747.1 - 0.0041 17.5 1.0 0.014 15.9 0.2 2.4 2 1 1 3 3 2 1 Miro-like protein SRPRB PF09439.5 EGG41747.1 - 0.0042 16.3 1.1 0.0083 15.3 0.7 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EGG41747.1 - 0.0058 15.8 0.5 0.016 14.4 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EGG41747.1 - 0.0096 14.8 0.1 0.021 13.7 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Arf PF00025.16 EGG41747.1 - 0.012 14.8 5.2 0.059 12.6 3.0 2.4 1 1 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.4 EGG41747.1 - 0.017 14.5 6.9 0.21 11.0 3.6 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EGG41747.1 - 0.019 14.6 0.3 0.046 13.4 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EGG41747.1 - 0.021 15.1 0.2 0.069 13.4 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 EGG41747.1 - 0.024 14.4 1.7 0.77 9.5 0.3 3.0 2 2 1 3 3 3 0 Dynamin family cobW PF02492.14 EGG41747.1 - 0.045 13.1 5.2 1.6 8.1 0.2 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EGG41747.1 - 0.24 11.2 3.3 1.4 8.8 0.1 2.9 2 1 0 3 3 3 0 AAA domain DUF1192 PF06698.6 EGG41747.1 - 1.2 8.9 8.5 0.72 9.7 0.3 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) NTPase_1 PF03266.10 EGG41747.1 - 8.1 6.1 9.8 4.7 6.8 0.2 4.0 3 2 1 4 4 4 0 NTPase Trm56 PF01994.11 EGG41748.1 - 4.2e-50 168.5 0.3 6.7e-50 167.8 0.2 1.3 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SPOUT_MTase_2 PF14419.1 EGG41748.1 - 0.0026 16.9 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP HMG_box_2 PF09011.5 EGG41748.1 - 0.045 14.1 0.3 0.092 13.1 0.2 1.4 1 0 0 1 1 1 0 HMG-box domain DXP_reductoisom PF02670.11 EGG41748.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF531 PF04407.7 EGG41748.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF531) TFIIE_alpha PF02002.12 EGG41749.1 - 8.8e-18 63.7 1.0 1.5e-17 62.9 0.7 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EGG41749.1 - 0.0062 15.8 0.7 0.014 14.7 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding DUF3834 PF12916.2 EGG41749.1 - 0.023 13.6 0.2 0.032 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) TrmB PF01978.14 EGG41749.1 - 0.028 14.1 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB D5_N PF08706.6 EGG41749.1 - 0.09 12.8 0.4 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 D5 N terminal like Sigma70_r3 PF04539.11 EGG41749.1 - 0.11 12.4 0.7 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 Zn_ribbon_recom PF13408.1 EGG41749.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DNA_ligase_ZBD PF03119.11 EGG41749.1 - 0.15 11.7 0.1 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Elf1 PF05129.8 EGG41749.1 - 0.45 10.2 3.8 1 9.0 2.7 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C4_Topoisom PF01396.14 EGG41749.1 - 0.73 9.3 3.7 0.63 9.5 0.2 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Aldedh PF00171.17 EGG41750.1 - 9.4e-142 472.5 0.1 1.1e-141 472.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hemerythrin PF01814.18 EGG41752.1 - 2.3e-11 43.9 0.4 1.1e-10 41.7 0.1 2.2 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain Methyltransf_4 PF02390.12 EGG41752.1 - 0.0031 16.6 2.0 0.0031 16.6 1.4 1.5 2 0 0 2 2 2 1 Putative methyltransferase IZUMO PF15005.1 EGG41752.1 - 0.05 13.6 1.7 0.068 13.2 0.4 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion SWIB PF02201.13 EGG41753.1 - 0.0051 16.4 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF4662 PF15578.1 EGG41753.1 - 2 7.9 6.6 1.7 8.1 4.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4662) RibD_C PF01872.12 EGG41754.1 - 7e-52 175.9 0.1 7.8e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Amidohydro_1 PF01979.15 EGG41755.1 - 3.7e-26 92.5 0.3 2.1e-25 90.1 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGG41755.1 - 5.7e-11 42.0 0.1 2.2e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EGG41755.1 - 1e-09 38.8 0.0 0.0015 18.6 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EGG41755.1 - 1.8e-06 27.4 0.1 0.00044 19.5 0.0 2.6 2 1 1 3 3 3 2 Amidohydrolase family GGDN PF05165.7 EGG41756.1 - 1.8e-50 171.3 0.0 2.5e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 GGDN family Guanylate_cyc PF00211.15 EGG41756.1 - 0.001 18.4 0.5 0.0019 17.5 0.1 1.7 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain MAF_flag10 PF01973.13 EGG41756.1 - 0.06 12.8 0.1 0.22 10.9 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF115 NOG1 PF06858.9 EGG41756.1 - 0.09 12.6 1.8 0.22 11.4 0.0 2.4 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) DMRL_synthase PF00885.14 EGG41757.1 - 5.2e-24 84.5 0.3 5.9e-24 84.3 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF3356 PF11836.3 EGG41757.1 - 0.081 12.7 0.2 0.55 10.0 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3356) Senescence PF06911.7 EGG41757.1 - 0.081 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Senescence-associated protein DHBP_synthase PF00926.14 EGG41758.1 - 6.5e-63 211.4 0.1 7.5e-63 211.2 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PAF-AH_p_II PF03403.8 EGG41758.1 - 0.092 11.0 0.0 0.13 10.4 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lum_binding PF00677.12 EGG41759.1 - 2.5e-45 152.2 10.7 3.9e-25 87.5 0.4 2.0 2 0 0 2 2 2 2 Lumazine binding domain TPR_11 PF13414.1 EGG41760.1 - 1.8e-29 101.1 7.9 2.1e-11 43.2 0.1 3.5 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EGG41760.1 - 6.2e-23 79.4 7.7 4.3e-07 29.2 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGG41760.1 - 1.2e-17 63.6 1.6 7.1e-06 25.8 0.1 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG41760.1 - 4.4e-16 57.4 0.4 0.0021 17.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EGG41760.1 - 5.7e-12 45.6 7.0 9.8e-06 25.6 0.5 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGG41760.1 - 7e-12 45.6 0.0 0.00019 21.9 0.0 3.1 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG41760.1 - 4.9e-10 38.4 12.3 0.0072 16.0 0.3 6.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGG41760.1 - 1.4e-09 36.9 0.2 0.025 14.3 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG41760.1 - 1.2e-08 34.5 4.0 0.23 11.7 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGG41760.1 - 1.2e-08 34.7 0.0 2.1 9.1 0.0 5.2 1 1 5 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG41760.1 - 1.5e-08 34.8 0.5 0.019 15.2 0.0 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGG41760.1 - 1.8e-07 30.8 0.0 0.025 14.4 0.0 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGG41760.1 - 4e-07 29.7 0.0 0.016 15.0 0.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG41760.1 - 1.7e-05 24.5 3.4 3 7.8 0.0 4.6 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EGG41760.1 - 0.00013 22.1 0.1 5.9 7.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 EGG41760.1 - 0.00022 20.1 1.5 0.0055 15.5 0.1 2.2 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 Phage_Treg PF04761.7 EGG41760.1 - 0.00081 19.1 0.0 0.031 14.0 0.0 2.6 2 0 0 2 2 2 1 Lactococcus bacteriophage putative transcription regulator TPR_15 PF13429.1 EGG41760.1 - 0.0011 18.0 0.3 0.0096 15.0 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EGG41760.1 - 0.0012 18.7 0.8 0.065 13.1 0.2 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EGG41760.1 - 0.0012 18.6 0.1 2 8.2 0.0 3.9 1 1 3 4 4 4 1 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 EGG41760.1 - 0.0014 18.2 0.2 0.65 9.6 0.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF627) Alkyl_sulf_dimr PF14863.1 EGG41760.1 - 0.0017 18.6 0.1 0.78 9.9 0.1 2.3 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation DUF4615 PF15393.1 EGG41760.1 - 0.028 14.6 0.6 0.05 13.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) UvsY PF11056.3 EGG41760.1 - 0.64 10.1 5.6 2.2 8.4 0.0 3.1 2 1 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY Response_reg PF00072.19 EGG41761.1 - 1.8e-18 66.5 0.1 2.3e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF2608 PF11019.3 EGG41761.1 - 0.0014 17.6 1.6 0.0026 16.7 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) Viral_Hsp90 PF03225.9 EGG41761.1 - 0.0027 16.0 0.3 0.0033 15.7 0.2 1.1 1 0 0 1 1 1 1 Viral heat shock protein Hsp90 homologue Gemini_AC4_5 PF04807.7 EGG41762.1 - 0.095 12.1 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region TrmB PF01978.14 EGG41762.1 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Med2 PF11214.3 EGG41762.1 - 0.2 11.6 3.7 0.81 9.7 0.1 2.3 2 1 0 2 2 2 0 Mediator complex subunit 2 RNA_pol_Rpb1_3 PF04983.13 EGG41762.1 - 0.51 10.0 7.0 0.68 9.6 1.0 2.4 1 1 0 2 2 2 0 RNA polymerase Rpb1, domain 3 HpcH_HpaI PF03328.9 EGG41763.1 - 1.3e-42 145.1 0.0 1.6e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EGG41763.1 - 1.1e-15 57.2 0.1 1.9e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 EGG41763.1 - 0.042 12.4 0.1 0.058 12.0 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Sua5_yciO_yrdC PF01300.13 EGG41764.1 - 5.4e-60 201.7 0.0 8.9e-60 200.9 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EGG41764.1 - 5.4e-28 97.5 0.1 9.8e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding EF-hand_1 PF00036.27 EGG41764.1 - 0.061 12.6 0.4 0.51 9.7 0.0 2.7 3 0 0 3 3 3 0 EF hand DUF1792 PF08759.6 EGG41764.1 - 0.066 12.8 1.9 0.44 10.1 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1792) PA28_alpha PF02251.13 EGG41764.1 - 0.14 12.3 1.0 0.69 10.1 0.0 2.6 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit ADH_zinc_N PF00107.21 EGG41765.1 - 5.3e-31 106.8 0.1 1e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGG41765.1 - 2.6e-22 78.6 0.0 4.4e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGG41765.1 - 6e-16 59.5 0.1 1.2e-15 58.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 EGG41765.1 - 0.052 13.5 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal dsDNA_bind PF01984.15 EGG41766.1 - 7.5e-24 83.7 2.4 8.5e-24 83.6 1.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S19e PF01090.14 EGG41767.1 - 1.3e-48 164.0 0.0 1.4e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RuvB_C PF05491.8 EGG41767.1 - 0.11 12.0 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB C-terminus Pyr_redox_2 PF07992.9 EGG41768.1 - 2e-14 53.9 0.0 2.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG41768.1 - 0.001 19.4 0.7 0.0053 17.1 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG41768.1 - 0.0035 17.4 0.7 4.8 7.1 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rpr2 PF04032.11 EGG41769.1 - 4e-17 61.8 1.8 5e-17 61.5 1.3 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Sec23_Sec24 PF04810.10 EGG41769.1 - 0.00099 18.6 1.3 0.14 11.7 0.1 2.2 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger DUF3268 PF11672.3 EGG41769.1 - 0.011 15.8 0.2 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) C1_1 PF00130.17 EGG41769.1 - 0.066 12.9 0.9 0.12 12.1 0.6 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cript PF10235.4 EGG41769.1 - 0.27 11.6 2.3 1.4 9.2 1.6 2.0 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT EMG1 PF03587.9 EGG41770.1 - 1.9e-42 144.8 0.4 2.2e-42 144.6 0.3 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF217 PF02697.9 EGG41770.1 - 0.046 13.9 0.6 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Uncharacterized ACR, COG1753 Glyco_hydro_35 PF01301.14 EGG41771.1 - 0.0024 17.2 0.0 0.0089 15.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 EGG41771.1 - 0.015 14.4 0.1 0.037 13.1 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase DUF4296 PF14129.1 EGG41771.1 - 0.07 13.2 0.2 0.33 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Ribonuc_red_lgC PF02867.10 EGG41772.1 - 2.5e-154 514.7 0.0 6.3e-154 513.4 0.0 1.7 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGG41772.1 - 7.8e-32 108.9 0.0 1.7e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGG41772.1 - 1.1e-23 83.4 2.1 3.5e-23 81.8 0.8 2.3 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EGG41773.1 - 2.9e-20 71.8 0.0 1.2e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.2 EGG41773.1 - 6.8e-10 38.5 0.0 2.2e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.11 EGG41773.1 - 3.5e-08 33.7 1.4 6.7e-07 29.6 0.0 3.7 4 1 1 5 5 5 1 ATP cone domain HTH_24 PF13412.1 EGG41773.1 - 0.041 13.2 0.2 1.4 8.3 0.0 2.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF35 PF01796.12 EGG41774.1 - 1.4e-08 34.8 0.2 1.9e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain zinc_ribbon_2 PF13240.1 EGG41774.1 - 0.00014 21.2 4.0 0.00025 20.4 2.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DUF35_N PF12172.3 EGG41774.1 - 0.00016 21.4 0.1 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 EGG41774.1 - 0.015 15.0 0.3 0.026 14.3 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon PHF5 PF03660.9 EGG41774.1 - 0.049 13.6 0.2 0.073 13.1 0.2 1.3 1 0 0 1 1 1 0 PHF5-like protein TFIIS_C PF01096.13 EGG41774.1 - 0.063 12.9 2.6 3 7.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2072 PF09845.4 EGG41774.1 - 0.12 12.3 1.4 0.16 11.9 0.9 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-ribbon_3 PF13248.1 EGG41774.1 - 0.17 11.1 2.1 0.39 9.9 1.5 1.7 1 1 0 1 1 1 0 zinc-ribbon domain CpXC PF14353.1 EGG41774.1 - 0.35 10.8 1.7 0.48 10.3 0.4 1.7 1 1 1 2 2 2 0 CpXC protein Nudix_N_2 PF14803.1 EGG41774.1 - 4.3 7.0 5.8 17 5.1 0.1 2.7 3 0 0 3 3 3 0 Nudix N-terminal Thiolase_C PF02803.13 EGG41775.1 - 5.9e-12 45.0 1.3 3.6e-10 39.3 0.0 2.9 2 2 2 4 4 4 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 EGG41775.1 - 6.2e-08 31.9 0.0 4.7e-07 29.0 0.0 2.3 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGG41775.1 - 0.00022 20.7 0.2 0.055 12.9 0.1 2.6 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGG41775.1 - 0.029 14.2 0.4 2.3 8.1 0.0 3.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain zf-C4_Topoisom PF01396.14 EGG41776.1 - 1.8e-07 30.5 7.7 3.1e-06 26.5 0.6 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.7 EGG41776.1 - 0.03 13.9 10.1 0.62 9.7 1.1 3.2 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.1 EGG41776.1 - 0.15 12.3 8.0 1.1 9.6 0.6 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain CN_hydrolase PF00795.17 EGG41777.1 - 1.4e-32 112.5 0.0 2e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Frag1 PF10277.4 EGG41777.1 - 0.1 12.0 1.1 0.16 11.4 0.8 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Tautomerase PF01361.16 EGG41778.1 - 6.1e-14 51.3 0.0 6.5e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.1 EGG41778.1 - 3.1e-08 33.5 0.0 3.2e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme DUF1904 PF08921.6 EGG41778.1 - 0.015 15.3 0.0 0.015 15.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) Tautomerase_3 PF14832.1 EGG41778.1 - 0.024 14.6 0.0 0.025 14.5 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme DUF1906 PF08924.6 EGG41778.1 - 0.088 12.6 0.0 0.091 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Rhomboid PF01694.17 EGG41779.1 - 2.3e-30 105.5 18.0 2.3e-30 105.5 12.5 1.6 2 0 0 2 2 2 1 Rhomboid family Glyco_trans_1_3 PF13528.1 EGG41782.1 - 5.9e-16 58.5 0.0 9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EGG41782.1 - 2.7e-13 49.9 0.3 5.1e-12 45.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.1 EGG41782.1 - 0.01 16.0 0.0 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 StbA PF06406.6 EGG41782.1 - 0.051 12.5 2.8 0.33 9.8 1.1 2.1 2 0 0 2 2 2 0 StbA protein NAD_Gly3P_dh_N PF01210.18 EGG41782.1 - 0.11 12.2 0.5 1.9 8.1 0.0 2.5 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Nit_Regul_Hom PF10126.4 EGG41782.1 - 0.43 10.3 3.1 0.31 10.8 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII AA_kinase PF00696.23 EGG41783.1 - 2.9e-20 72.8 0.1 6e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EGG41783.1 - 0.12 11.8 0.5 0.31 10.5 0.3 1.6 1 0 0 1 1 1 0 ACT domain DUF2892 PF11127.3 EGG41784.1 - 0.6 9.9 2.9 0.46 10.3 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Aminotran_4 PF01063.14 EGG41785.1 - 4.2e-44 150.7 0.0 4.8e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV Flocculin PF00624.13 EGG41786.1 - 0.21 11.4 1.8 0.29 11.0 1.3 1.2 1 0 0 1 1 1 0 Flocculin repeat Methyltransf_11 PF08241.7 EGG41787.1 - 1.4e-15 57.5 0.0 2.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG41787.1 - 1.2e-13 51.3 0.0 2.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG41787.1 - 3.8e-13 49.2 0.1 5e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG41787.1 - 4.8e-08 32.8 0.0 8.2e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG41787.1 - 1.9e-07 31.4 0.0 3.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG41787.1 - 2e-06 27.8 0.0 3.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41787.1 - 4.3e-05 24.0 0.0 5.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGG41787.1 - 0.00011 21.3 0.1 0.00014 21.0 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EGG41787.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.3 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EGG41787.1 - 0.0037 16.4 0.0 0.0059 15.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EGG41787.1 - 0.0039 16.3 0.1 0.0061 15.7 0.1 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ribosomal_L18_c PF14204.1 EGG41787.1 - 0.0055 17.2 2.1 0.14 12.6 0.1 2.2 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4145 PF13643.1 EGG41787.1 - 0.013 15.3 0.2 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) MTS PF05175.9 EGG41787.1 - 0.015 14.7 0.0 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain DUF1308 PF07000.6 EGG41787.1 - 0.057 12.0 0.0 0.078 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) HATPase_c PF02518.21 EGG41788.1 - 6.3e-24 83.8 0.0 1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG41788.1 - 4e-12 45.9 0.1 8.8e-12 44.8 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG41788.1 - 8.8e-07 28.5 0.1 2.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 EGG41788.1 - 6.7e-05 22.5 0.2 0.00023 20.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAPKK1_Int PF08923.5 EGG41788.1 - 0.036 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting HATPase_c_2 PF13581.1 EGG41788.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain NfeD PF01957.13 EGG41788.1 - 0.26 11.4 1.6 4.7 7.3 0.4 2.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding 7TMR-DISM_7TM PF07695.6 EGG41788.1 - 0.35 10.5 42.0 1.7 8.2 20.7 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling TMEM154 PF15102.1 EGG41788.1 - 0.59 9.8 4.6 4.1 7.0 3.2 2.2 1 1 0 1 1 1 0 TMEM154 protein family Response_reg PF00072.19 EGG41789.1 - 4.9e-22 78.0 0.6 5.7e-22 77.8 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain YcgR PF07317.7 EGG41789.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.6 1 1 0 1 1 1 0 Flagellar regulator YcgR Polyketide_cyc PF03364.15 EGG41790.1 - 3.1e-06 27.2 0.0 4.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COX15-CtaA PF02628.10 EGG41792.1 - 1.7e-25 89.5 6.2 2.2e-25 89.1 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Syndecan PF01034.15 EGG41792.1 - 4.3 7.0 5.1 3.4 7.3 1.4 2.1 2 1 0 2 2 2 0 Syndecan domain Copper-bind PF00127.15 EGG41793.1 - 8.6e-15 54.7 0.4 1.9e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.10 EGG41793.1 - 2.3e-11 43.4 0.7 1.6e-05 24.6 0.0 3.1 2 2 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EGG41793.1 - 4.4e-09 36.1 0.0 0.00038 20.2 0.0 2.7 2 0 0 2 2 2 2 Cupredoxin-like domain Cu_bind_like PF02298.12 EGG41793.1 - 1.9e-08 33.9 0.0 0.0048 16.6 0.0 2.9 2 1 0 2 2 2 2 Plastocyanin-like domain SoxE PF06525.6 EGG41793.1 - 8.1e-08 31.7 0.8 0.011 15.0 0.0 2.6 2 1 0 2 2 2 2 Sulfocyanin (SoxE) Cu-oxidase_2 PF07731.9 EGG41793.1 - 1.3e-05 24.6 0.0 0.017 14.6 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase COX2 PF00116.15 EGG41793.1 - 0.0016 18.2 0.0 0.91 9.3 0.0 2.8 3 0 0 3 3 3 2 Cytochrome C oxidase subunit II, periplasmic domain CHU_C PF13585.1 EGG41793.1 - 0.011 15.5 0.1 3 7.8 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of CHU protein family PGBA_N PF15436.1 EGG41793.1 - 0.013 14.7 0.0 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal PPC PF04151.10 EGG41793.1 - 0.18 12.7 4.6 0.24 12.4 0.2 2.6 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain COX1 PF00115.15 EGG41794.1 - 9.4e-143 476.0 60.3 1.2e-142 475.7 41.8 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.15 EGG41795.1 - 5.1e-20 71.4 1.9 2e-17 63.1 0.1 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.1 EGG41795.1 - 6.2e-05 22.8 0.0 7.7e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Cupredoxin-like domain DUF2391 PF09622.5 EGG41796.1 - 0.048 12.8 0.1 0.052 12.7 0.1 1.0 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) DUF2566 PF10753.4 EGG41796.1 - 0.11 12.4 0.2 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2566) His_Phos_1 PF00300.17 EGG41797.1 - 5e-35 120.9 0.0 5.9e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CRM1_C PF08767.6 EGG41797.1 - 0.069 12.0 0.3 0.14 11.0 0.0 1.6 2 1 0 2 2 2 0 CRM1 C terminal F420_oxidored PF03807.12 EGG41798.1 - 8.2e-18 64.6 0.1 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGG41798.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGG41798.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EGG41798.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EGG41798.1 - 0.014 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGG41798.1 - 0.021 14.7 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PDH PF02153.12 EGG41798.1 - 0.047 12.5 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase DUF308 PF03729.8 EGG41799.1 - 0.0032 17.4 1.1 0.3 11.1 0.1 2.1 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) Gram_pos_anchor PF00746.16 EGG41799.1 - 0.0067 16.1 0.4 0.081 12.7 0.0 2.0 2 0 0 2 2 2 1 Gram positive anchor YfzA PF14118.1 EGG41799.1 - 0.02 14.9 0.8 0.032 14.3 0.5 1.4 1 1 0 1 1 1 0 YfzA-like protein Tetraspannin PF00335.15 EGG41799.1 - 0.044 13.0 2.2 0.054 12.7 1.5 1.0 1 0 0 1 1 1 0 Tetraspanin family DctQ PF04290.7 EGG41799.1 - 0.063 13.0 1.0 0.086 12.5 0.7 1.3 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF334 PF03904.8 EGG41799.1 - 0.11 11.8 0.2 0.1 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF202 PF02656.10 EGG41799.1 - 1.3 9.2 3.4 13 6.0 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) VPEP PF07589.6 EGG41799.1 - 4.6 7.2 7.3 1.5 8.8 0.6 2.2 2 0 0 2 2 2 0 PEP-CTERM motif Pyridox_oxidase PF01243.15 EGG41800.1 - 2.1e-17 62.9 0.0 4.9e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EGG41800.1 - 1.8e-10 40.8 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YmdB PF13277.1 EGG41800.1 - 0.0038 16.2 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 YmdB-like protein Aida_C2 PF14186.1 EGG41800.1 - 0.038 13.2 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Cytoskeletal adhesion DUF2373 PF10180.4 EGG41800.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Aminotran_1_2 PF00155.16 EGG41801.1 - 1.5e-56 191.9 0.0 1.7e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGG41801.1 - 4.2e-08 32.6 0.0 6.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGG41801.1 - 2.6e-07 29.7 0.0 4.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGG41801.1 - 0.00012 20.5 0.0 0.00016 20.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGG41801.1 - 0.004 16.3 0.0 0.011 14.9 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase HRDC PF00570.18 EGG41801.1 - 0.053 13.2 0.0 15 5.4 0.0 3.5 4 0 0 4 4 4 0 HRDC domain EMP24_GP25L PF01105.19 EGG41802.1 - 0.0056 16.4 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Big_3 PF07523.7 EGG41802.1 - 0.034 14.2 0.3 0.1 12.6 0.2 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF3244 PF11589.3 EGG41802.1 - 0.035 13.8 2.4 0.54 9.9 0.5 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3244) FlgD_ig PF13860.1 EGG41802.1 - 0.047 13.4 0.5 0.99 9.1 0.1 2.3 1 1 1 2 2 2 0 FlgD Ig-like domain Spore_YhaL PF14147.1 EGG41802.1 - 0.29 10.6 1.6 0.34 10.3 0.1 1.9 2 0 0 2 2 2 0 Sporulation protein YhaL EMP70 PF02990.11 EGG41803.1 - 0.063 11.7 5.0 0.093 11.1 3.5 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF2104 PF09877.4 EGG41803.1 - 0.35 10.8 6.2 5.7 6.9 0.2 3.1 3 1 0 3 3 3 0 Predicted membrane protein (DUF2104) DUF2653 PF10850.3 EGG41804.1 - 0.056 13.7 0.2 0.062 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) tRNA-synt_2c PF01411.14 EGG41804.1 - 0.07 11.4 0.1 0.083 11.1 0.1 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) adh_short_C2 PF13561.1 EGG41805.1 - 2.1e-09 37.5 0.0 2.6e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG41805.1 - 9.5e-05 22.3 0.1 0.055 13.3 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 EGG41805.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF59 PF01883.14 EGG41806.1 - 1.2e-15 57.2 0.3 2.7e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF59 PqqD PF05402.7 EGG41806.1 - 5.4e-09 35.9 0.1 8.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) HemN_C PF06969.11 EGG41806.1 - 0.027 14.5 0.2 0.059 13.4 0.2 1.5 1 0 0 1 1 1 0 HemN C-terminal domain IF-2B PF01008.12 EGG41807.1 - 1.6e-86 289.8 0.8 1.6e-86 289.8 0.5 1.4 2 0 0 2 2 2 1 Initiation factor 2 subunit family RRM_1 PF00076.17 EGG41807.1 - 0.079 12.5 0.1 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyridox_oxidase PF01243.15 EGG41808.1 - 4.6e-13 48.9 0.0 1.2e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GatB_Yqey PF02637.13 EGG41808.1 - 0.028 14.1 1.4 0.028 14.1 1.0 1.5 2 0 0 2 2 2 0 GatB domain DUF2024 PF09630.5 EGG41809.1 - 1.3e-33 114.5 3.0 1.4e-33 114.3 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) RE_TdeIII PF09520.5 EGG41809.1 - 0.0072 15.6 0.1 0.01 15.1 0.1 1.2 1 1 0 1 1 1 1 Type II restriction endonuclease, TdeIII CCG PF02754.11 EGG41809.1 - 0.031 14.2 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich domain CPDase PF07823.6 EGG41810.1 - 8.2e-16 58.0 2.4 1.2e-15 57.5 1.7 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EGG41810.1 - 4.8e-07 29.6 0.0 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 EGG41810.1 - 0.0072 16.2 0.1 3.5 7.6 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase HVSL PF09749.4 EGG41810.1 - 0.008 15.2 0.7 0.015 14.3 0.1 1.7 3 0 0 3 3 3 1 Uncharacterised conserved protein HTH_22 PF13309.1 EGG41810.1 - 0.099 12.4 1.2 0.39 10.5 0.3 2.4 2 1 0 2 2 2 0 HTH domain UPF0449 PF15136.1 EGG41810.1 - 0.11 12.6 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 ROK PF00480.15 EGG41811.1 - 3.5e-49 167.0 1.9 5e-49 166.5 1.3 1.2 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.15 EGG41811.1 - 0.0011 18.3 0.6 0.006 15.9 0.3 2.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.8 EGG41811.1 - 0.0014 18.1 0.1 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region FGGY_N PF00370.16 EGG41811.1 - 0.078 12.2 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Cpn60_TCP1 PF00118.19 EGG41812.1 - 1.1e-162 542.0 16.2 1.4e-162 541.7 11.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Adenine_deam_C PF13382.1 EGG41813.1 - 1.2e-47 161.2 0.0 2.2e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.15 EGG41813.1 - 1.5e-17 64.2 0.0 3.6e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGG41813.1 - 6.9e-09 35.4 0.6 2.8e-08 33.4 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGG41813.1 - 0.0023 17.2 0.0 0.15 11.2 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGG41813.1 - 0.0094 16.0 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase DUF2099 PF09872.4 EGG41813.1 - 0.048 12.6 0.1 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) Ribosomal_L44 PF00935.14 EGG41814.1 - 1.8e-25 88.7 8.6 1.8e-25 88.7 6.0 1.3 2 0 0 2 2 2 1 Ribosomal protein L44 C1_1 PF00130.17 EGG41814.1 - 0.087 12.5 0.8 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.2 EGG41814.1 - 1.7 8.9 5.2 5.1 7.4 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_S27e PF01667.12 EGG41815.1 - 5.4e-18 64.2 1.1 6.4e-18 64.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 Zn_Tnp_IS91 PF14319.1 EGG41815.1 - 0.0022 17.4 0.9 0.0025 17.3 0.6 1.1 1 0 0 1 1 1 1 Transposase zinc-binding domain zinc_ribbon_6 PF14599.1 EGG41815.1 - 0.0063 16.2 2.6 0.034 13.9 1.8 1.9 1 1 0 1 1 1 1 Zinc-ribbon zf-ribbon_3 PF13248.1 EGG41815.1 - 0.0083 15.2 3.3 0.021 14.0 2.3 1.7 1 1 1 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGG41815.1 - 0.011 15.0 0.7 0.015 14.6 0.5 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2318 PF10080.4 EGG41815.1 - 0.017 14.9 0.5 0.02 14.6 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_1 PF00130.17 EGG41815.1 - 0.02 14.5 0.6 0.028 14.1 0.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 EGG41815.1 - 0.023 14.4 2.7 1 9.1 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger DZR PF12773.2 EGG41815.1 - 0.029 14.1 2.2 0.067 13.0 1.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGG41815.1 - 0.032 14.1 0.8 0.055 13.4 0.5 1.4 1 1 0 1 1 1 0 Zinc ribbon domain YhfH PF14149.1 EGG41815.1 - 0.038 13.7 1.6 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 YhfH-like protein FYVE PF01363.16 EGG41815.1 - 0.048 13.5 0.2 0.059 13.2 0.2 1.2 1 0 0 1 1 1 0 FYVE zinc finger zf-dskA_traR PF01258.12 EGG41815.1 - 0.053 13.2 0.3 6.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger TerY-C PF15616.1 EGG41815.1 - 0.061 13.2 0.7 0.065 13.1 0.5 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain RRN7 PF11781.3 EGG41815.1 - 0.064 12.7 0.7 5.9 6.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 HypA PF01155.14 EGG41815.1 - 0.065 12.9 0.5 0.071 12.7 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 EGG41815.1 - 0.068 12.9 3.4 0.11 12.1 2.3 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.1 EGG41815.1 - 0.072 13.4 2.2 0.74 10.1 1.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-UDP PF14569.1 EGG41815.1 - 0.1 12.3 0.4 0.12 12.1 0.3 1.1 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_2 PF13240.1 EGG41815.1 - 0.12 11.9 1.9 9.4 5.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain ZZ PF00569.12 EGG41815.1 - 0.12 11.9 5.4 0.84 9.2 0.3 2.2 1 1 1 2 2 2 0 Zinc finger, ZZ type DNA_RNApol_7kD PF03604.8 EGG41815.1 - 0.12 11.8 3.8 1.7 8.1 2.7 2.1 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_7 PF15269.1 EGG41815.1 - 0.14 12.0 0.2 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Zinc-finger IBR PF01485.16 EGG41815.1 - 0.17 11.7 1.4 0.21 11.4 1.0 1.2 1 0 0 1 1 1 0 IBR domain DUF3133 PF11331.3 EGG41815.1 - 0.22 11.1 2.7 7.4 6.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) Sgf11 PF08209.6 EGG41815.1 - 0.22 10.8 4.1 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn_Tnp_IS1595 PF12760.2 EGG41815.1 - 0.23 11.3 1.8 0.6 9.9 1.4 1.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 EGG41815.1 - 0.26 11.4 2.6 0.41 10.8 1.8 1.3 1 1 0 1 1 1 0 CHY zinc finger DUF1451 PF07295.6 EGG41815.1 - 0.32 10.7 1.4 0.42 10.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) TFIIS_C PF01096.13 EGG41815.1 - 0.42 10.2 3.5 25 4.6 2.4 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-HYPF PF07503.7 EGG41815.1 - 0.52 9.7 3.0 7 6.1 0.1 2.2 2 0 0 2 2 2 0 HypF finger GCC2_GCC3 PF07699.8 EGG41815.1 - 0.68 9.5 4.0 2.1 7.9 2.7 1.7 1 1 0 1 1 1 0 GCC2 and GCC3 zf-C2H2_3 PF13878.1 EGG41815.1 - 1.4 8.5 5.1 3.1 7.4 0.3 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Eapp_C PF10238.4 EGG41815.1 - 1.6 8.5 5.5 8.5 6.2 0.6 2.0 1 1 1 2 2 2 0 E2F-associated phosphoprotein GATA PF00320.22 EGG41815.1 - 2.1 7.7 5.6 45 3.5 0.2 2.2 1 1 1 2 2 2 0 GATA zinc finger UPF0547 PF10571.4 EGG41815.1 - 4.1 7.1 5.6 37 4.1 3.9 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF3797 PF12677.2 EGG41815.1 - 4.4 6.9 8.6 3.7 7.2 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) NTP_transf_3 PF12804.2 EGG41816.1 - 1.2e-13 51.4 0.0 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGG41816.1 - 1e-07 31.7 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.18 EGG41816.1 - 0.00024 20.5 0.1 0.00038 19.8 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NIF PF03031.13 EGG41816.1 - 0.00084 19.0 0.2 0.1 12.2 0.1 2.3 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase CTP_transf_3 PF02348.14 EGG41816.1 - 0.05 13.2 0.1 0.061 12.9 0.1 1.5 1 1 0 1 1 1 0 Cytidylyltransferase Peptidase_C98 PF15499.1 EGG41816.1 - 0.11 11.7 0.2 0.11 11.7 0.2 1.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CobS PF02654.10 EGG41817.1 - 1.1e-53 182.2 20.4 1.2e-53 182.1 14.1 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase CobD_Cbib PF03186.8 EGG41818.1 - 4.7e-96 321.3 0.0 5.7e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 CobD/Cbib protein AAA_26 PF13500.1 EGG41819.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EGG41820.1 - 4.6e-13 49.0 0.1 5e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 EGG41820.1 - 1.2e-05 25.0 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGG41820.1 - 0.0012 18.5 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGG41820.1 - 0.0069 16.7 0.2 0.0084 16.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGG41820.1 - 0.0075 15.7 0.3 0.019 14.4 0.1 1.8 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGG41820.1 - 0.011 15.7 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 EGG41820.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.15 EGG41820.1 - 0.019 14.6 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 EGG41820.1 - 0.03 15.1 0.0 0.032 15.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 EGG41820.1 - 0.033 13.7 0.1 0.038 13.5 0.1 1.2 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_31 PF13614.1 EGG41820.1 - 0.04 13.8 0.2 0.082 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.6 EGG41820.1 - 0.048 12.7 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein SRP54 PF00448.17 EGG41820.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 EGG41820.1 - 0.077 12.6 0.1 0.19 11.3 0.1 1.7 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.22 EGG41820.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.3 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EGG41820.1 - 0.087 13.0 0.1 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EGG41820.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Part of AAA domain UPF0181 PF03701.9 EGG41820.1 - 0.52 9.6 1.9 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Aminotran_1_2 PF00155.16 EGG41821.1 - 3.5e-56 190.7 0.0 4.3e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EGG41821.1 - 9.9e-05 21.1 0.2 0.013 14.1 0.0 2.2 1 1 1 2 2 2 2 Allinase Aminotran_5 PF00266.14 EGG41821.1 - 0.057 12.1 0.0 0.19 10.4 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Semialdhyde_dhC PF02774.13 EGG41822.1 - 1.1e-35 123.1 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EGG41822.1 - 4.8e-29 101.1 0.0 9.4e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGG41822.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 EGG41822.1 - 0.043 13.2 0.6 1.1 8.7 0.1 2.5 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Paramyxo_PCT PF14320.1 EGG41822.1 - 0.045 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered GFO_IDH_MocA PF01408.17 EGG41822.1 - 0.069 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 EGG41822.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase AsnC_trans_reg PF01037.16 EGG41823.1 - 4.7e-13 48.6 0.4 6.8e-13 48.1 0.1 1.5 2 0 0 2 2 2 1 AsnC family HTH_24 PF13412.1 EGG41823.1 - 3.1e-10 39.2 1.9 1e-09 37.6 0.7 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EGG41823.1 - 2.6e-07 30.0 0.1 6.4e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR PF01047.17 EGG41823.1 - 7.9e-05 22.2 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.7 EGG41823.1 - 0.00017 21.1 0.5 0.00034 20.1 0.1 1.7 2 0 0 2 2 2 1 HTH domain HTH_27 PF13463.1 EGG41823.1 - 0.00047 20.4 0.1 0.0047 17.2 0.0 2.3 1 1 2 3 3 3 1 Winged helix DNA-binding domain B-block_TFIIIC PF04182.7 EGG41823.1 - 0.0029 17.4 0.3 0.004 16.9 0.2 1.5 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EGG41823.1 - 0.0035 16.9 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 MarR family Sulfolobus_pRN PF05584.6 EGG41823.1 - 0.0097 15.8 0.2 0.023 14.6 0.1 1.6 1 0 0 1 1 1 1 Sulfolobus plasmid regulatory protein FerA PF08165.6 EGG41823.1 - 0.011 15.3 0.3 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 FerA (NUC095) domain TrmB PF01978.14 EGG41823.1 - 0.013 15.2 0.6 0.023 14.3 0.1 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MotA_activ PF09114.5 EGG41823.1 - 0.031 14.0 0.2 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Transcription factor MotA, activation domain HTH_34 PF13601.1 EGG41823.1 - 0.042 13.8 0.1 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 EGG41823.1 - 0.049 13.7 0.2 0.38 10.9 0.1 2.2 2 1 0 2 2 2 0 Transcriptional regulator HTH_psq PF05225.11 EGG41823.1 - 0.06 12.9 0.2 0.097 12.2 0.2 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_20 PF12840.2 EGG41823.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain UbiA PF01040.13 EGG41824.1 - 1.4e-24 86.7 18.5 1.7e-24 86.4 12.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Cytokin_check_N PF10407.4 EGG41825.1 - 0.058 13.0 0.4 0.072 12.7 0.3 1.3 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Cas_Cas6 PF01881.11 EGG41825.1 - 0.1 12.8 0.7 0.1 12.7 0.5 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas6 Phage_int_SAM_1 PF02899.12 EGG41826.1 - 0.036 14.2 0.7 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3800 PF12686.2 EGG41826.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF883 PF05957.8 EGG41826.1 - 0.14 12.5 0.1 24 5.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MscS_porin PF12795.2 EGG41826.1 - 0.26 10.5 4.0 0.15 11.3 0.4 2.1 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain ApoLp-III PF07464.6 EGG41826.1 - 0.32 11.0 5.0 3.1 7.8 3.1 2.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ERp29 PF07749.7 EGG41826.1 - 0.49 11.0 3.4 16 6.1 0.0 3.0 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF3106 PF11304.3 EGG41826.1 - 3.4 8.1 11.9 1.1 9.6 2.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) DUF1789 PF08748.6 EGG41826.1 - 4.8 7.3 9.2 1.6 8.8 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) Inhibitor_I29 PF08246.7 EGG41828.1 - 0.024 14.8 1.6 0.024 14.8 1.1 2.9 3 1 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) Ribonuc_2-5A PF06479.7 EGG41829.1 - 0.0011 18.8 2.5 0.0015 18.3 1.3 1.6 1 1 0 1 1 1 1 Ribonuclease 2-5A Phage_min_cap2 PF06152.6 EGG41829.1 - 0.0021 17.1 1.7 0.0023 16.9 1.2 1.1 1 0 0 1 1 1 1 Phage minor capsid protein 2 Sec5 PF15469.1 EGG41829.1 - 0.0046 16.7 4.2 0.045 13.4 2.9 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec5 ERp29 PF07749.7 EGG41829.1 - 0.013 16.1 4.2 1.1 9.9 0.4 2.6 1 1 2 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain DDE_Tnp_ISL3 PF01610.12 EGG41829.1 - 0.02 14.4 9.4 0.11 12.0 0.3 2.2 1 1 1 2 2 2 0 Transposase RRF PF01765.14 EGG41829.1 - 0.025 14.0 1.3 0.05 13.0 0.4 1.8 1 1 1 2 2 2 0 Ribosome recycling factor Dak2 PF02734.12 EGG41829.1 - 0.056 13.1 0.0 0.23 11.1 0.0 1.9 1 1 1 2 2 2 0 DAK2 domain FCH PF00611.18 EGG41829.1 - 0.057 13.6 7.4 2.6 8.2 3.8 2.9 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Chalcone PF02431.10 EGG41829.1 - 0.078 12.3 2.5 0.32 10.3 1.6 2.1 1 1 0 1 1 1 0 Chalcone-flavanone isomerase YkyA PF10368.4 EGG41829.1 - 0.08 12.2 5.2 0.53 9.5 1.3 2.4 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein SF-assemblin PF06705.6 EGG41829.1 - 0.1 11.6 1.4 0.87 8.6 1.0 2.0 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF4415 PF14384.1 EGG41829.1 - 0.16 12.1 6.0 1.4 9.1 0.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4415) DUF1215 PF06744.7 EGG41829.1 - 0.17 11.5 4.9 0.098 12.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1215) DUF2884 PF11101.3 EGG41829.1 - 0.2 10.9 9.5 0.26 10.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Spore_III_AB PF09548.5 EGG41829.1 - 0.21 11.3 8.5 0.64 9.7 5.5 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2309 PF10070.4 EGG41829.1 - 0.21 9.6 6.3 0.24 9.4 4.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) T4SS PF07996.6 EGG41829.1 - 0.23 11.3 8.4 0.38 10.5 5.8 1.3 1 1 0 1 1 1 0 Type IV secretion system proteins ATC_hydrolase PF14196.1 EGG41829.1 - 0.34 11.3 3.9 0.5 10.7 1.9 1.8 1 1 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase His_Phos_1 PF00300.17 EGG41829.1 - 0.35 10.9 3.1 6.9 6.7 0.0 2.5 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 1) DASH_Dad2 PF08654.5 EGG41829.1 - 0.5 10.3 8.4 3.7 7.6 1.6 2.8 1 1 2 3 3 3 0 DASH complex subunit Dad2 ALIX_LYPXL_bnd PF13949.1 EGG41829.1 - 0.52 9.2 8.3 0.87 8.4 5.6 1.6 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV CMAS PF02353.15 EGG41829.1 - 0.94 8.5 9.6 0.75 8.8 2.4 2.4 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase DUF745 PF05335.8 EGG41829.1 - 1.5 8.3 5.2 0.88 9.0 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF2714 PF10896.3 EGG41829.1 - 2.5 7.8 7.1 0.65 9.8 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2714) OmpH PF03938.9 EGG41829.1 - 2.9 7.7 6.4 6.7 6.6 4.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YfbU PF03887.9 EGG41829.1 - 3.6 7.1 7.2 0.4 10.2 0.7 2.1 1 1 1 2 2 2 0 YfbU domain DUF4413 PF14372.1 EGG41829.1 - 4.6 7.2 8.6 0.37 10.7 1.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4413) DUF3080 PF11279.3 EGG41829.1 - 5 6.1 10.0 6.9 5.7 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) 4HBT PF03061.17 EGG41830.1 - 2.7e-10 40.2 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 EGG41830.1 - 0.00044 19.6 0.2 0.00064 19.0 0.1 1.3 1 0 0 1 1 1 1 MaoC like domain OspE PF02471.12 EGG41830.1 - 0.029 14.2 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Borrelia outer surface protein E Caenor_Her-1 PF09232.5 EGG41830.1 - 0.047 13.7 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 CTX_RstB PF07459.6 EGG41830.1 - 0.062 13.1 0.1 0.082 12.7 0.1 1.2 1 0 0 1 1 1 0 CTX phage RstB protein UbiD PF01977.11 EGG41831.1 - 5.3e-103 344.6 0.1 6.1e-103 344.4 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PGP_phosphatase PF09419.5 EGG41831.1 - 0.052 12.9 0.5 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Chlam_vir PF05475.6 EGG41832.1 - 0.026 13.6 0.2 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D RepA_N PF06970.6 EGG41834.1 - 0.029 14.1 0.2 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Wzy_C PF04932.10 EGG41835.1 - 0.06 13.1 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase FMN_red PF03358.10 EGG41837.1 - 1.3e-42 144.8 0.0 1.6e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGG41837.1 - 4.1e-10 39.5 0.0 5.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Pyr_redox PF00070.22 EGG41837.1 - 0.0056 17.0 0.0 0.016 15.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1474 PF07342.6 EGG41838.1 - 0.088 13.0 1.3 3.3 8.0 0.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1474) HxlR PF01638.12 EGG41839.1 - 3.1e-26 90.8 2.0 3.7e-26 90.5 1.4 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.17 EGG41839.1 - 0.0061 16.2 0.2 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 EGG41839.1 - 0.0099 15.8 0.2 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.9 EGG41839.1 - 0.011 15.5 0.3 0.024 14.3 0.0 1.8 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family HTH_20 PF12840.2 EGG41839.1 - 0.023 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.15 EGG41839.1 - 0.054 13.1 0.3 0.14 11.8 0.2 1.7 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 EGG41839.1 - 0.14 11.5 0.3 0.14 11.5 0.2 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Pirin PF02678.11 EGG41840.1 - 3.5e-37 126.5 0.2 6.4e-37 125.7 0.2 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGG41840.1 - 6.4e-34 116.1 0.1 4.4e-32 110.2 0.0 3.0 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EGG41840.1 - 0.0078 15.6 3.2 0.71 9.4 0.3 2.8 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.17 EGG41840.1 - 0.12 11.8 0.0 2.4 7.5 0.0 2.5 2 1 0 3 3 3 0 Cupin zf-CDGSH PF09360.5 EGG41841.1 - 8.2e-12 44.7 0.1 1e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type SnoaL PF07366.7 EGG41842.1 - 4.8e-14 52.0 0.0 6.7e-14 51.5 0.0 1.2 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EGG41842.1 - 2.6e-07 30.9 0.0 4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EGG41842.1 - 0.0054 16.9 0.0 0.009 16.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Chordopox_A13L PF05961.6 EGG41842.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF3172 PF11371.3 EGG41842.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Glyoxalase_2 PF12681.2 EGG41843.1 - 2.7e-15 56.8 0.0 2.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EGG41843.1 - 4.2e-15 55.8 1.4 3.3e-08 33.5 0.1 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGG41843.1 - 0.021 14.8 0.0 10 6.1 0.0 3.0 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EGG41843.1 - 0.065 12.9 0.1 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal DUF1724 PF08350.5 EGG41844.1 - 2.6e-06 26.8 0.1 2.6e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1724) PrgU PF09627.5 EGG41844.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.3 1 1 0 1 1 1 0 PrgU-like protein HTH_5 PF01022.15 EGG41845.1 - 0.0026 17.3 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.2 EGG41845.1 - 0.0033 17.1 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Copper-bind PF00127.15 EGG41846.1 - 0.00026 21.1 0.0 0.00067 19.8 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EGG41846.1 - 0.1 12.4 0.1 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 Cupredoxin-like domain DUF1499 PF07386.6 EGG41849.1 - 0.0017 18.5 0.0 0.002 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) DUF456 PF04306.8 EGG41850.1 - 0.015 15.2 0.1 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) TIR_2 PF13676.1 EGG41850.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 TIR domain Gly-zipper_Omp PF13488.1 EGG41850.1 - 0.16 11.6 8.6 0.31 10.7 6.0 1.4 1 1 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.4 EGG41850.1 - 0.37 10.9 3.1 0.54 10.4 2.1 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 EGG41850.1 - 0.66 9.6 9.7 1.1 9.0 6.7 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EGG41850.1 - 4.3 6.9 10.8 9.1 5.8 7.5 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper DivIC PF04977.10 EGG41851.1 - 0.027 13.9 3.3 0.72 9.3 0.6 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF2779 PF11074.3 EGG41851.1 - 0.03 14.3 0.2 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) ArsR PF09824.4 EGG41851.1 - 0.032 13.5 0.6 0.061 12.6 0.4 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator IncA PF04156.9 EGG41851.1 - 0.035 13.6 3.7 0.099 12.2 2.6 1.7 1 1 0 1 1 1 0 IncA protein MacB_PCD PF12704.2 EGG41851.1 - 0.043 13.4 0.1 0.083 12.4 0.1 1.5 1 0 0 1 1 1 0 MacB-like periplasmic core domain TatC PF00902.13 EGG41851.1 - 0.068 12.5 5.3 0.13 11.6 3.2 1.7 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) Imm23 PF15593.1 EGG41851.1 - 0.24 11.6 4.1 1 9.5 0.2 2.5 1 1 1 2 2 2 0 Immunity protein 23 CENP-H PF05837.7 EGG41851.1 - 0.6 10.3 5.1 14 5.9 3.5 2.3 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF2117 PF09890.4 EGG41852.1 - 0.046 12.9 2.6 0.055 12.6 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) AAA_11 PF13086.1 EGG41852.1 - 0.16 11.4 2.8 0.17 11.4 1.9 1.1 1 0 0 1 1 1 0 AAA domain DUF3979 PF13141.1 EGG41852.1 - 0.2 11.5 2.9 0.23 11.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Cu_amine_oxidN1 PF07833.6 EGG41852.1 - 0.2 11.9 1.5 0.26 11.6 1.0 1.2 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain ParBc PF02195.13 EGG41853.1 - 0.0015 18.5 0.0 0.0049 16.9 0.0 2.0 1 0 0 1 1 1 1 ParB-like nuclease domain RuvB_C PF05491.8 EGG41853.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus RE_TdeIII PF09520.5 EGG41854.1 - 3.5e-50 170.6 1.5 4e-50 170.4 1.0 1.0 1 0 0 1 1 1 1 Type II restriction endonuclease, TdeIII RE_EcoO109I PF14511.1 EGG41854.1 - 0.0011 18.3 2.3 0.1 11.9 1.6 2.6 1 1 0 1 1 1 1 Type II restriction endonuclease EcoO109I N6_N4_Mtase PF01555.13 EGG41856.1 - 6.7e-20 71.5 6.3 1.5e-15 57.3 0.1 3.0 3 0 0 3 3 3 2 DNA methylase Methyltransf_26 PF13659.1 EGG41856.1 - 3.1e-13 49.7 0.0 6.2e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGG41856.1 - 7.7e-05 22.3 0.4 0.0035 16.9 0.3 2.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EGG41856.1 - 0.00016 21.3 0.0 0.0086 15.6 0.0 2.4 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EGG41856.1 - 0.0031 17.1 0.9 0.016 14.8 0.4 2.5 1 1 1 2 2 2 1 Methyltransferase domain HTH_17 PF12728.2 EGG41856.1 - 0.006 16.8 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_18 PF12847.2 EGG41856.1 - 0.088 13.3 0.0 0.5 10.9 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain GHL12 PF14882.1 EGG41857.1 - 5.7e-09 35.9 19.4 0.0025 17.8 0.5 4.3 3 2 2 5 5 5 3 Hypothetical glycosyl hydrolase 12 RE_MjaI PF09568.5 EGG41857.1 - 0.44 10.0 5.3 14 5.1 0.1 3.0 3 0 0 3 3 3 0 MjaI restriction endonuclease NEAT PF05031.7 EGG41858.1 - 0.1 12.6 0.3 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Iron Transport-associated domain HxlR PF01638.12 EGG41859.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF1875 PF08961.5 EGG41860.1 - 0.016 14.5 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) HALZ PF02183.13 EGG41860.1 - 0.081 12.6 0.6 0.17 11.5 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Phage_integrase PF00589.17 EGG41860.1 - 0.11 12.0 1.4 1 8.9 0.1 2.0 2 0 0 2 2 2 0 Phage integrase family DUF4480 PF13715.1 EGG41861.1 - 1.9e-07 31.0 0.1 4.6e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) CarboxypepD_reg PF13620.1 EGG41861.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain TBD PF12845.2 EGG41861.1 - 1.2 8.7 5.2 0.18 11.3 0.5 1.9 2 0 0 2 2 2 0 TBD domain A2M_N PF01835.14 EGG41862.1 - 0.0027 17.9 0.0 0.0039 17.4 0.0 1.3 1 1 0 1 1 1 1 MG2 domain HSP20 PF00011.16 EGG41863.1 - 2.7e-09 36.7 0.8 4.6e-08 32.8 0.5 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EGG41863.1 - 0.00017 22.0 0.1 0.00026 21.4 0.1 1.2 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 EGG41863.1 - 0.0013 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Decorin_bind PF02352.10 EGG41864.1 - 0.03 14.3 0.2 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 Decorin binding protein Cu-oxidase_3 PF07732.10 EGG41865.1 - 5.8e-25 87.3 1.2 1.5e-24 85.9 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG41865.1 - 9.6e-18 64.0 3.8 1.5e-06 27.7 0.0 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 EGG41865.1 - 1.4e-10 41.0 0.0 0.00011 22.0 0.0 3.4 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.15 EGG41865.1 - 4.1e-06 26.9 3.0 0.0047 17.1 0.3 3.4 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family zf-C2H2_6 PF13912.1 EGG41866.1 - 0.055 13.4 1.7 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.7 EGG41866.1 - 0.056 12.7 4.1 2.8 7.3 0.6 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding RHH_3 PF12651.2 EGG41866.1 - 0.13 12.0 0.1 15 5.4 0.1 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain RecR PF02132.10 EGG41866.1 - 0.19 11.2 1.5 0.65 9.4 1.1 1.7 1 1 0 1 1 1 0 RecR protein zf-C2H2_3 PF13878.1 EGG41866.1 - 0.27 10.8 0.1 0.27 10.8 0.1 1.8 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Thioredoxin PF00085.15 EGG41867.1 - 9.9e-29 99.0 0.0 1.1e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGG41867.1 - 8.2e-09 35.4 0.1 7.9e-08 32.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGG41867.1 - 2.5e-08 34.0 0.2 1.3e-07 31.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EGG41867.1 - 1.1e-06 28.2 0.1 1.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EGG41867.1 - 2.4e-05 23.9 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EGG41867.1 - 8.8e-05 22.4 0.1 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.11 EGG41867.1 - 0.00013 20.7 0.0 0.00015 20.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin TraF PF13728.1 EGG41867.1 - 0.059 12.8 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.6 EGG41867.1 - 0.06 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.9 EGG41867.1 - 0.079 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GTP_EFTU PF00009.22 EGG41868.1 - 2.1e-32 112.1 0.0 6.4e-32 110.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGG41868.1 - 7.7e-23 80.4 0.5 2.1e-22 79.0 0.4 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.1 EGG41868.1 - 2e-09 36.9 0.5 2e-09 36.9 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGG41868.1 - 6.8e-08 32.4 0.3 8.9e-07 28.8 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 EGG41868.1 - 6.1e-06 26.7 0.0 2.9e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 EGG41868.1 - 2.4e-05 23.9 0.0 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU_D2 PF03144.20 EGG41868.1 - 0.00034 20.6 0.1 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 EGG41868.1 - 0.00056 19.7 0.4 0.13 12.1 0.0 2.9 1 1 0 2 2 2 1 Dynamin family Ras PF00071.17 EGG41868.1 - 0.002 17.5 0.1 0.029 13.7 0.0 2.6 2 1 0 2 2 2 1 Ras family cobW PF02492.14 EGG41868.1 - 0.042 13.2 1.1 1.9 7.9 0.1 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NDK PF00334.14 EGG41869.1 - 2.6e-32 111.4 0.0 2.8e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ribosomal_L24e PF01246.15 EGG41870.1 - 3.5e-19 68.4 0.6 3.7e-19 68.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e DUF581 PF04570.9 EGG41870.1 - 0.028 13.6 0.2 0.048 12.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF581) zf-MYND PF01753.13 EGG41870.1 - 0.028 14.2 0.0 0.04 13.8 0.0 1.5 1 1 0 1 1 1 0 MYND finger DUF2256 PF10013.4 EGG41870.1 - 0.036 13.8 6.2 5.1 6.9 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-FCS PF06467.9 EGG41870.1 - 0.26 10.9 2.8 0.21 11.2 0.7 1.7 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF329 PF03884.9 EGG41870.1 - 0.63 9.6 2.9 2.8 7.5 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF329) Ribosomal_S28e PF01200.13 EGG41871.1 - 4.2e-29 100.0 4.6 4.5e-29 99.9 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e KOW PF00467.24 EGG41871.1 - 0.044 13.5 1.0 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 KOW motif Ribosomal_L7Ae PF01248.21 EGG41872.1 - 1.4e-25 88.6 0.1 1.7e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 EGG41872.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF3055 PF11256.3 EGG41872.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3055) PGM_PMM_I PF02878.11 EGG41873.1 - 2.6e-37 127.4 0.0 4.5e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGG41873.1 - 2.5e-24 85.6 0.0 7.4e-24 84.0 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EGG41873.1 - 2.4e-23 82.3 0.0 4.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EGG41873.1 - 2.7e-09 36.8 0.0 6.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RTX PF02382.10 EGG41873.1 - 0.025 12.8 0.0 0.27 9.4 0.0 2.0 2 0 0 2 2 2 0 RTX N-terminal domain Formyl_trans_N PF00551.14 EGG41874.1 - 2.5e-43 147.7 0.1 3.5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.1 EGG41874.1 - 4.6e-09 35.8 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 EGG41874.1 - 0.0001 21.6 0.1 0.00044 19.6 0.0 2.1 1 1 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EGG41874.1 - 0.0086 16.3 1.2 0.032 14.5 0.0 2.6 1 1 2 3 3 3 1 ACT domain Creatininase PF02633.9 EGG41875.1 - 1.3e-54 184.8 0.0 1.5e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase LSM PF01423.17 EGG41876.1 - 6.5e-23 80.0 0.6 7.5e-23 79.8 0.4 1.0 1 0 0 1 1 1 1 LSM domain Flagellin_C PF00700.16 EGG41877.1 - 0.029 14.5 0.2 0.2 11.8 0.1 2.4 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region MTS_N PF08468.6 EGG41877.1 - 0.07 12.9 1.4 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal SH3_1 PF00018.23 EGG41877.1 - 0.26 10.7 1.2 0.55 9.6 0.8 1.5 1 0 0 1 1 1 0 SH3 domain Rib_5-P_isom_A PF06026.9 EGG41878.1 - 1.8e-51 173.8 0.2 2.3e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EGG41878.1 - 0.0032 17.1 0.2 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Yqai PF09466.5 EGG41878.1 - 0.13 12.2 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Hypothetical protein Yqai Cupredoxin_1 PF13473.1 EGG41879.1 - 5.1e-08 32.7 0.0 7.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Cu-oxidase_2 PF07731.9 EGG41879.1 - 0.073 12.5 0.8 9.2 5.7 0.0 2.2 1 1 0 2 2 2 0 Multicopper oxidase COX2 PF00116.15 EGG41879.1 - 0.1 12.4 0.1 0.2 11.5 0.0 1.6 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, periplasmic domain Amidohydro_4 PF13147.1 EGG41880.1 - 4.4e-24 85.9 0.0 1e-23 84.7 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGG41880.1 - 5.5e-10 39.4 1.0 5e-09 36.2 0.7 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGG41880.1 - 1e-08 34.8 3.1 4.1e-08 32.9 2.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGG41880.1 - 3e-07 30.0 0.2 2.4e-06 27.0 0.1 2.4 1 1 0 1 1 1 1 Amidohydrolase family TatD_DNase PF01026.16 EGG41880.1 - 6.9e-05 22.1 0.1 0.00018 20.8 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase Hom_end PF05204.9 EGG41880.1 - 0.06 13.2 0.0 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Homing endonuclease zf-ribbon_3 PF13248.1 EGG41881.1 - 6.9e-09 34.6 3.5 1.2e-08 33.9 2.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGG41881.1 - 1.1e-08 34.2 11.5 2.6e-07 29.9 3.7 1.7 1 1 1 2 2 2 2 zinc-ribbon domain DZR PF12773.2 EGG41881.1 - 1.5e-06 27.9 1.0 2e-06 27.4 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 EGG41881.1 - 1.4e-05 24.6 2.3 3.9e-05 23.2 1.6 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 EGG41881.1 - 0.0074 15.9 9.2 0.087 12.5 0.2 2.6 3 0 0 3 3 3 2 Nudix N-terminal GFA PF04828.9 EGG41881.1 - 0.015 15.2 3.5 0.47 10.4 0.1 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 EGG41881.1 - 0.022 14.4 3.6 2.1 8.0 0.4 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Prok-RING_1 PF14446.1 EGG41881.1 - 0.023 14.4 1.5 0.032 13.9 1.0 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-NADH-PPase PF09297.6 EGG41881.1 - 0.056 12.9 6.1 5.8 6.5 4.2 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.5 EGG41881.1 - 0.061 12.8 3.1 2 8.0 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.17 EGG41881.1 - 0.07 12.8 0.9 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRN7 PF11781.3 EGG41881.1 - 0.075 12.5 0.4 11 5.6 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc-ribbons_6 PF07191.7 EGG41881.1 - 0.08 12.7 0.7 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbons TF_Zn_Ribbon PF08271.7 EGG41881.1 - 0.11 11.8 2.5 4.4 6.7 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C3HC4_3 PF13920.1 EGG41881.1 - 0.11 12.1 0.4 0.16 11.6 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NOB1_Zn_bind PF08772.6 EGG41881.1 - 0.21 11.4 7.8 2.6 7.9 0.5 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Auto_anti-p27 PF06677.7 EGG41881.1 - 0.24 11.2 4.3 2.4 7.9 2.9 2.2 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 EGG41881.1 - 0.26 10.9 1.5 0.5 10.0 1.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-tcix PF14952.1 EGG41881.1 - 0.73 9.2 6.2 2.5 7.4 0.5 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding YhfH PF14149.1 EGG41881.1 - 0.82 9.5 4.3 7.7 6.3 0.1 2.3 1 1 1 2 2 2 0 YhfH-like protein RecR PF02132.10 EGG41881.1 - 0.95 8.9 3.0 6.8 6.2 0.1 2.2 1 1 1 2 2 2 0 RecR protein zinc_ribbon_2 PF13240.1 EGG41882.1 - 1.2e-05 24.6 2.8 1.9e-05 23.9 1.9 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGG41882.1 - 0.00021 20.3 3.8 0.00035 19.6 2.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EGG41882.1 - 0.00035 20.3 1.7 0.00053 19.7 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 EGG41882.1 - 0.013 15.2 0.6 0.019 14.6 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 PAH PF02671.16 EGG41882.1 - 0.032 13.8 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 Paired amphipathic helix repeat Sipho_tail PF05709.6 EGG41882.1 - 0.044 12.9 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Phage tail protein YkyA PF10368.4 EGG41882.1 - 0.044 13.1 0.5 0.056 12.7 0.3 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Nudix_N_2 PF14803.1 EGG41882.1 - 1.2 8.8 5.0 4.4 7.0 0.5 2.2 2 0 0 2 2 2 0 Nudix N-terminal YhfH PF14149.1 EGG41882.1 - 4.8 7.0 6.7 2.9 7.7 0.4 2.9 2 1 1 3 3 3 0 YhfH-like protein Thioredoxin PF00085.15 EGG41883.1 - 7.9e-32 109.0 0.1 8.9e-32 108.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGG41883.1 - 2.3e-12 46.8 0.3 4.3e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGG41883.1 - 6.3e-11 42.4 0.0 2e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGG41883.1 - 1.9e-07 30.9 0.1 3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EGG41883.1 - 9.6e-07 28.4 0.1 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EGG41883.1 - 2.5e-06 27.2 0.1 3e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 EGG41883.1 - 1.4e-05 24.7 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG41883.1 - 5.3e-05 22.7 0.3 0.00014 21.4 0.2 1.6 1 1 0 1 1 1 1 Redoxin HyaE PF07449.6 EGG41883.1 - 0.00015 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 EGG41883.1 - 0.00066 19.7 0.1 0.16 11.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EGG41883.1 - 0.0031 17.3 0.1 0.008 16.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain DUF953 PF06110.6 EGG41883.1 - 0.0032 16.8 0.3 0.011 15.2 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) TraF PF13728.1 EGG41883.1 - 0.0067 15.9 0.0 0.008 15.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF836 PF05768.9 EGG41883.1 - 0.036 14.3 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 EGG41883.1 - 0.076 12.5 0.1 0.91 9.0 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.19 EGG41883.1 - 0.088 12.8 0.2 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin GLTP PF08718.6 EGG41883.1 - 0.11 12.4 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) TrbC_Ftype PF09673.5 EGG41883.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DZR PF12773.2 EGG41884.1 - 3.5e-06 26.7 10.8 0.00033 20.4 2.8 2.4 2 0 0 2 2 2 2 Double zinc ribbon PRC PF05239.11 EGG41884.1 - 4.5e-06 26.4 0.5 8.4e-06 25.5 0.4 1.4 1 0 0 1 1 1 1 PRC-barrel domain zinc_ribbon_2 PF13240.1 EGG41884.1 - 8.2e-05 21.9 7.4 8.2e-05 21.9 5.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGG41884.1 - 0.00014 20.8 6.4 0.00014 20.8 4.4 2.5 3 0 0 3 3 3 1 zinc-ribbon domain GFA PF04828.9 EGG41884.1 - 0.0018 18.1 6.1 5.7 6.9 0.1 3.4 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.19 EGG41884.1 - 0.02 14.8 11.1 1.5 8.7 0.7 3.2 3 0 0 3 3 3 0 B-box zinc finger zinc-ribbons_6 PF07191.7 EGG41884.1 - 0.034 13.9 6.9 7.5 6.4 0.9 3.2 3 0 0 3 3 3 0 zinc-ribbons Metaviral_G PF09595.5 EGG41884.1 - 0.069 12.7 3.0 0.1 12.2 2.1 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein A2L_zn_ribbon PF08792.5 EGG41884.1 - 0.11 12.0 0.0 0.11 12.0 0.0 4.4 3 1 0 3 3 3 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.8 EGG41884.1 - 0.29 10.6 10.7 2 7.9 0.0 4.2 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit DUF3279 PF11682.3 EGG41884.1 - 0.36 10.4 5.9 12 5.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) Prim_Zn_Ribbon PF08273.7 EGG41884.1 - 0.56 10.3 9.6 22 5.2 0.1 3.6 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase RRN7 PF11781.3 EGG41884.1 - 0.76 9.3 11.4 2.4 7.7 1.0 3.5 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-AD PF07776.10 EGG41884.1 - 1.1 9.3 5.9 1.2 9.1 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) DUF1033 PF06279.6 EGG41884.1 - 1.2 8.9 4.6 0.87 9.4 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) PHD PF00628.24 EGG41884.1 - 2.5 7.8 9.2 15 5.4 0.1 3.3 3 0 0 3 3 3 0 PHD-finger Cript PF10235.4 EGG41884.1 - 5.5 7.4 7.8 0.83 10.0 0.1 3.0 3 1 0 3 3 3 0 Microtubule-associated protein CRIPT GCC2_GCC3 PF07699.8 EGG41884.1 - 6.7 6.3 12.9 1.5 8.5 2.9 3.3 3 0 0 3 3 3 0 GCC2 and GCC3 Peptidase_S24 PF00717.18 EGG41885.1 - 2.2e-07 30.3 4.1 4.1e-07 29.5 0.3 2.3 2 0 0 2 2 2 1 Peptidase S24-like SOR PF07682.6 EGG41885.1 - 0.026 13.1 0.2 0.026 13.1 0.2 1.6 2 0 0 2 2 2 0 Sulphur oxygenase reductase Peptidase_S49_N PF08496.5 EGG41885.1 - 0.056 13.2 0.5 0.056 13.2 0.4 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Vpu PF00558.14 EGG41885.1 - 3.2 7.3 8.7 0.4 10.2 0.3 2.4 2 0 0 2 2 2 0 Vpu protein TrbC PF04956.8 EGG41885.1 - 5.2 7.1 6.5 10 6.1 1.1 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF1510 PF07423.6 EGG41885.1 - 6 6.1 11.1 0.083 12.2 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) HpaB_N PF11794.3 EGG41886.1 - 1.2e-89 300.1 0.0 2.5e-89 299.1 0.0 1.5 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.8 EGG41886.1 - 2.2e-70 235.6 0.2 3.2e-70 235.1 0.1 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Bt_P21 PF05560.6 EGG41886.1 - 0.078 12.3 0.2 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein ATP-grasp_5 PF13549.1 EGG41887.1 - 1.7e-79 266.1 0.7 3.2e-79 265.2 0.5 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EGG41887.1 - 1e-51 174.1 0.8 2.9e-51 172.7 0.5 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGG41887.1 - 9.4e-22 77.3 0.4 3.1e-21 75.6 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.14 EGG41887.1 - 1.3e-09 38.3 3.6 3.6e-09 37.0 0.6 2.8 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 EGG41887.1 - 1.1e-05 24.8 1.6 2.3e-05 23.8 1.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGG41887.1 - 6.1e-05 22.8 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGG41887.1 - 0.0014 17.9 0.2 0.0026 17.0 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dak1_2 PF13684.1 EGG41887.1 - 0.0019 17.1 0.6 0.0056 15.6 0.2 1.9 1 1 1 2 2 2 1 Dihydroxyacetone kinase family ATP-grasp PF02222.17 EGG41887.1 - 0.084 12.2 0.1 0.24 10.7 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain RNase_H PF00075.19 EGG41888.1 - 3.7e-17 62.9 0.0 4.2e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGG41888.1 - 3.5e-11 42.7 0.1 4.4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like Hex_IIIa PF02455.11 EGG41888.1 - 0.0061 15.3 0.0 0.0076 14.9 0.0 1.0 1 0 0 1 1 1 1 Hexon-associated protein (IIIa) DUF1886 PF09171.5 EGG41888.1 - 0.069 12.1 0.1 1 8.3 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1886) DUF349 PF03993.7 EGG41888.1 - 0.12 12.5 0.3 0.32 11.1 0.2 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF475 PF04332.10 EGG41889.1 - 0.0018 17.9 3.9 0.0023 17.5 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF475) Tox-WTIP PF15654.1 EGG41889.1 - 0.085 12.4 0.4 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif E1-N PF14463.1 EGG41889.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain DUF3493 PF11998.3 EGG41889.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) DUF4199 PF13858.1 EGG41889.1 - 0.35 10.7 10.1 0.14 12.0 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF3270 PF11674.3 EGG41889.1 - 0.36 10.8 4.1 1.6 8.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF1385 PF07136.6 EGG41889.1 - 0.46 9.5 4.0 0.55 9.2 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) GtrA PF04138.9 EGG41889.1 - 3.1 7.7 8.4 0.27 11.2 0.4 2.5 2 1 1 3 3 3 0 GtrA-like protein Tmemb_14 PF03647.8 EGG41890.1 - 0.23 11.8 3.7 0.12 12.7 0.9 1.7 2 0 0 2 2 2 0 Transmembrane proteins 14C HTH_5 PF01022.15 EGG41891.1 - 2.7e-09 36.5 0.3 8.8e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 EGG41891.1 - 7.6e-07 28.4 1.2 1.2e-06 27.8 0.8 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 EGG41891.1 - 2.6e-06 27.1 0.0 6.3e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.14 EGG41891.1 - 2.9e-06 26.9 0.2 6.7e-06 25.7 0.0 1.6 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 EGG41891.1 - 0.00048 19.7 0.8 0.00061 19.3 0.1 1.5 2 0 0 2 2 1 1 HTH domain HTH_45 PF14947.1 EGG41891.1 - 0.00065 19.4 2.4 0.00089 19.0 1.6 1.4 1 1 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.2 EGG41891.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.5 1 1 1 2 2 2 1 MarR family MarR PF01047.17 EGG41891.1 - 0.0033 17.1 0.2 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 EGG41891.1 - 0.0037 17.2 0.4 0.0053 16.7 0.1 1.4 2 0 0 2 2 1 1 Winged helix DNA-binding domain Phage_rep_org_N PF09681.5 EGG41891.1 - 0.0075 15.8 0.4 0.0079 15.7 0.3 1.1 1 0 0 1 1 1 1 N-terminal phage replisome organiser (Phage_rep_org_N) HTH_Crp_2 PF13545.1 EGG41891.1 - 0.0095 15.7 0.1 0.16 11.7 0.0 2.1 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain B-block_TFIIIC PF04182.7 EGG41891.1 - 0.012 15.4 0.2 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC KorB PF08535.5 EGG41891.1 - 0.023 14.8 0.1 0.037 14.1 0.0 1.4 1 1 0 1 1 1 0 KorB domain HTH_12 PF08461.5 EGG41891.1 - 0.026 14.2 0.3 0.046 13.4 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain LexA_DNA_bind PF01726.11 EGG41891.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_10 PF04967.7 EGG41891.1 - 0.044 13.3 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 HTH DNA binding domain DUF4423 PF14394.1 EGG41891.1 - 0.053 13.0 0.6 0.17 11.4 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_29 PF13551.1 EGG41891.1 - 0.058 13.5 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix Rrf2 PF02082.15 EGG41891.1 - 0.068 13.2 0.4 0.16 12.0 0.1 1.7 1 1 1 2 2 2 0 Transcriptional regulator DUF2089 PF09862.4 EGG41891.1 - 0.092 12.5 0.3 0.26 11.0 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) HTH_9 PF08221.6 EGG41891.1 - 0.12 12.2 0.2 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain MobC PF05713.6 EGG41891.1 - 0.16 11.9 1.3 0.24 11.3 0.2 1.9 2 1 0 2 2 2 0 Bacterial mobilisation protein (MobC) Radical_SAM PF04055.16 EGG41892.1 - 9.3e-16 58.4 0.1 2.5e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily NicO PF03824.11 EGG41893.1 - 7.7e-09 35.2 19.9 1.8e-08 34.0 13.8 1.6 1 1 0 1 1 1 1 High-affinity nickel-transport protein DsbD_2 PF13386.1 EGG41893.1 - 6.6e-08 32.5 7.7 9.1e-08 32.0 4.4 1.8 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Gly-zipper_OmpA PF13436.1 EGG41893.1 - 0.37 10.4 0.1 0.37 10.4 0.1 2.2 2 2 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Thioredoxin_3 PF13192.1 EGG41895.1 - 1.2e-10 41.0 0.1 1.6e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.19 EGG41895.1 - 0.00074 19.4 0.1 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin KaiB PF07689.7 EGG41895.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 KaiB domain DsbD PF02683.10 EGG41896.1 - 7.9e-18 64.8 17.3 7.9e-18 64.8 12.0 1.7 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 EGG41896.1 - 3.3e-08 33.5 21.1 3.3e-08 33.5 14.6 2.4 2 1 1 3 3 3 2 Cytochrome C biogenesis protein transmembrane region NicO PF03824.11 EGG41896.1 - 2.2 7.5 14.9 0.47 9.7 4.3 2.5 2 1 0 2 2 2 0 High-affinity nickel-transport protein HTH_AsnC-type PF13404.1 EGG41897.1 - 4.8e-13 48.4 0.0 7.9e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EGG41897.1 - 3.8e-10 38.9 0.1 6.6e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EGG41897.1 - 2.3e-05 23.9 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Arc_trans_TRASH PF08394.5 EGG41897.1 - 8e-05 22.7 4.2 0.00014 21.9 2.9 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain HTH_5 PF01022.15 EGG41897.1 - 0.00038 20.0 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.4 EGG41897.1 - 0.00097 19.0 1.5 0.031 14.1 1.0 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_Tnp_ISL3 PF13542.1 EGG41897.1 - 0.0021 17.2 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EGG41897.1 - 0.0033 17.3 0.1 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_9 PF08221.6 EGG41897.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain ATPase-cat_bd PF12156.3 EGG41897.1 - 0.012 16.1 1.0 0.012 16.1 0.7 1.8 3 0 0 3 3 1 0 Putative metal-binding domain of cation transport ATPase HTH_23 PF13384.1 EGG41897.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 EGG41897.1 - 0.029 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4423 PF14394.1 EGG41897.1 - 0.035 13.6 0.1 0.11 11.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) MarR_2 PF12802.2 EGG41897.1 - 0.036 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 MarR family DUF1272 PF06906.6 EGG41897.1 - 0.042 13.7 1.2 0.073 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Sigma70_r4_2 PF08281.7 EGG41897.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Fe_dep_repress PF01325.14 EGG41897.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF2089 PF09862.4 EGG41897.1 - 0.087 12.6 0.9 0.46 10.2 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2089) FeoC PF09012.5 EGG41897.1 - 0.094 12.4 0.0 0.094 12.4 0.0 2.2 2 1 1 3 3 3 0 FeoC like transcriptional regulator Utp14 PF04615.8 EGG41897.1 - 0.11 10.6 1.1 0.14 10.3 0.8 1.1 1 0 0 1 1 1 0 Utp14 protein zf-FCS PF06467.9 EGG41897.1 - 0.15 11.7 5.0 0.34 10.5 3.4 1.6 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif He_PIG PF05345.7 EGG41898.1 - 6.2e-05 22.9 0.6 6.2e-05 22.9 0.4 2.5 3 0 0 3 3 3 1 Putative Ig domain PixA PF12306.3 EGG41898.1 - 0.024 14.4 0.8 0.024 14.4 0.6 1.5 2 0 0 2 2 2 0 Inclusion body protein Nucleo_P87 PF07267.6 EGG41898.1 - 1.1 7.8 5.8 1.3 7.5 4.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Trypan_PARP PF05887.6 EGG41898.1 - 1.9 8.3 13.2 0.041 13.6 3.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.6 EGG41899.1 - 8.5e-05 22.4 2.9 8.5e-05 22.4 2.0 1.7 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF4369 PF14289.1 EGG41899.1 - 0.013 15.5 0.2 0.025 14.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) DUF2345 PF10106.4 EGG41899.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) CarboxypepD_reg PF13620.1 EGG41899.1 - 0.072 13.1 1.5 0.15 12.0 1.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain EB PF01683.13 EGG41899.1 - 0.13 12.3 7.1 4.1 7.5 0.6 3.9 2 2 0 2 2 2 0 EB module PLRV_ORF5 PF01690.12 EGG41899.1 - 0.34 10.0 6.5 0.45 9.6 4.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein A2M_N PF01835.14 EGG41900.1 - 0.0011 19.1 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 MG2 domain Tachystatin_B PF11478.3 EGG41901.1 - 0.12 12.1 0.2 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B HTH_10 PF04967.7 EGG41901.1 - 0.16 11.5 0.1 18 4.9 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain Cation_efflux PF01545.16 EGG41902.1 - 5e-77 258.7 28.4 6.1e-63 212.5 7.6 3.0 2 1 1 3 3 3 3 Cation efflux family BON PF04972.12 EGG41902.1 - 0.057 13.1 0.9 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 BON domain DUF4131 PF13567.1 EGG41902.1 - 0.39 10.0 3.5 4.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AMP-binding_C_2 PF14535.1 EGG41902.1 - 0.97 9.5 10.4 1.2 9.2 1.0 3.2 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain ATP_synt_I PF03899.10 EGG41902.1 - 3.2 7.9 11.7 0.19 11.9 0.9 2.8 2 1 1 3 3 3 0 ATP synthase I chain Zip PF02535.17 EGG41903.1 - 4.1e-07 29.3 18.2 4.1e-07 29.3 12.6 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter Cu-oxidase_3 PF07732.10 EGG41904.1 - 3.8e-23 81.4 6.2 3.6e-20 71.8 0.5 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG41904.1 - 3.4e-20 71.9 10.8 3.8e-09 36.1 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase EMP24_GP25L PF01105.19 EGG41905.1 - 0.04 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1366 PF07104.6 EGG41906.1 - 0.025 14.1 0.5 0.04 13.5 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) HTH_24 PF13412.1 EGG41906.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 EGG41906.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix Ribosomal_S13 PF00416.17 EGG41907.1 - 8.8e-27 93.6 0.0 1.1e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 S4 PF01479.20 EGG41908.1 - 1.2e-10 40.6 0.1 3.9e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 EGG41908.1 - 9.6e-06 25.9 2.1 1.1e-05 25.7 0.9 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SIS PF01380.17 EGG41909.1 - 1.8e-51 173.1 3.9 2.3e-28 98.4 1.8 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 EGG41909.1 - 3.1e-24 85.4 0.1 1.3e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGG41909.1 - 1.8e-19 69.6 0.1 1.3e-15 57.0 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EGG41909.1 - 2.9e-18 65.7 0.8 9.8e-18 64.0 0.0 2.3 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGG41909.1 - 5.8e-08 31.7 0.2 1e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EGG41909.1 - 1.5e-05 24.6 10.9 0.00058 19.5 0.4 4.4 4 1 1 5 5 5 2 SIS domain eIF-1a PF01176.14 EGG41909.1 - 0.077 12.4 0.1 5.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 DBI_PRT PF02277.12 EGG41910.1 - 2.5e-26 92.5 0.2 3.9e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyltransferase Lactamase_B PF00753.22 EGG41911.1 - 1.2e-27 96.8 1.2 1.5e-27 96.5 0.9 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGG41911.1 - 2.7e-06 27.0 0.9 4.9e-06 26.2 0.5 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1776 PF08643.5 EGG41911.1 - 0.076 12.1 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) YjeF_N PF03853.10 EGG41912.1 - 1.6e-48 164.5 0.0 1.8e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Translin PF01997.11 EGG41913.1 - 2.3e-31 108.9 0.8 3.1e-31 108.5 0.6 1.2 1 0 0 1 1 1 1 Translin family RNA_pol_N PF01194.12 EGG41914.1 - 9e-30 102.4 0.4 1.1e-29 102.1 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit PhaP_Bmeg PF09602.5 EGG41914.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) tRNA-synt_2 PF00152.15 EGG41914.1 - 0.043 12.5 0.0 0.049 12.3 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Chordopox_RPO7 PF05864.7 EGG41914.1 - 0.18 11.9 1.4 0.63 10.1 0.9 1.8 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Enolase_C PF00113.17 EGG41915.1 - 4.4e-57 193.3 0.1 6.1e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGG41915.1 - 1.2e-26 93.2 0.0 2.9e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Enolase, N-terminal domain CW_binding_2 PF04122.7 EGG41915.1 - 0.00044 20.3 2.2 0.001 19.2 0.3 2.4 3 0 0 3 3 3 1 Putative cell wall binding repeat 2 Ribosomal_S2 PF00318.15 EGG41916.1 - 8.7e-34 116.5 0.3 3.9e-16 58.9 0.4 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Memo PF01875.12 EGG41917.1 - 5.5e-82 274.7 0.0 6.2e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.13 EGG41917.1 - 0.0011 18.0 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GHMP_kinases_N PF00288.21 EGG41918.1 - 1e-19 70.3 0.7 2e-19 69.3 0.2 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGG41918.1 - 2.1e-12 47.0 0.0 4.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DUF573 PF04504.9 EGG41918.1 - 0.001 19.2 0.5 0.0023 18.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF573 Tubulin_C PF03953.12 EGG41918.1 - 0.025 14.6 0.4 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Tubulin C-terminal domain I_LWEQ PF01608.12 EGG41918.1 - 0.026 14.4 0.4 0.042 13.8 0.3 1.4 1 0 0 1 1 1 0 I/LWEQ domain DUF4288 PF14119.1 EGG41918.1 - 0.57 10.3 2.9 13 5.9 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4288) AA_kinase PF00696.23 EGG41919.1 - 4.5e-29 101.6 0.0 5.2e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF1967 PF09269.6 EGG41919.1 - 0.016 14.8 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) NUDIX PF00293.23 EGG41920.1 - 2.1e-14 53.3 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain polyprenyl_synt PF00348.12 EGG41921.1 - 3.8e-69 232.4 0.4 4.9e-69 232.0 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EGG41921.1 - 0.00029 20.1 0.0 0.00061 19.1 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain tRNA-synt_1c PF00749.16 EGG41922.1 - 1.7e-75 253.6 0.0 2.6e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGG41922.1 - 3.5e-22 78.9 0.1 7.1e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain FAA_hydrolase PF01557.13 EGG41923.1 - 5e-67 225.5 0.0 6.5e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 EGG41923.1 - 0.00014 22.1 0.2 0.00078 19.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) Acetyltransf_7 PF13508.1 EGG41924.1 - 2.2e-07 30.9 0.2 1.7e-06 28.0 0.0 2.3 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGG41924.1 - 2.4e-07 30.6 0.0 1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGG41924.1 - 0.00056 20.0 0.0 0.0069 16.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGG41924.1 - 0.0007 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGG41924.1 - 0.002 18.2 0.1 0.0036 17.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TaqI_C PF12950.2 EGG41924.1 - 0.019 14.7 2.4 0.034 13.9 1.4 1.8 1 1 0 1 1 1 0 TaqI-like C-terminal specificity domain FmdE PF02663.9 EGG41924.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Acetyltransf_9 PF13527.1 EGG41924.1 - 0.053 13.3 0.0 0.28 11.0 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGG41924.1 - 0.14 11.9 0.1 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Rieske PF00355.21 EGG41925.1 - 1.5e-16 59.7 0.0 1.8e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EGG41925.1 - 5.1e-08 32.5 0.0 5.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0147 PF03685.8 EGG41926.1 - 1.3e-32 111.4 2.8 1.5e-32 111.3 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) UPF0253 PF06786.7 EGG41926.1 - 0.002 18.2 0.0 1.2 9.2 0.0 2.4 1 1 0 2 2 2 2 Uncharacterised protein family (UPF0253) Bacillus_HBL PF05791.6 EGG41926.1 - 0.0024 17.2 1.2 0.0024 17.2 0.8 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Glyco_hydro_20b PF02838.10 EGG41926.1 - 0.019 15.5 0.6 0.023 15.2 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DUF2262 PF10020.4 EGG41926.1 - 0.047 13.8 0.4 0.047 13.8 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DUF3461 PF11944.3 EGG41926.1 - 0.091 12.6 0.4 0.67 9.7 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) UvrB PF12344.3 EGG41926.1 - 0.45 10.0 2.1 1.5 8.4 0.2 2.2 2 0 0 2 2 2 0 Ultra-violet resistance protein B PA-IIL PF07472.6 EGG41927.1 - 0.1 12.8 0.1 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) Methyltransf_11 PF08241.7 EGG41927.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGG41927.1 - 0.13 11.8 0.6 0.18 11.4 0.4 1.5 1 1 0 1 1 1 0 Methyltransferase domain CorA PF01544.13 EGG41929.1 - 9.5e-61 205.3 7.8 1.5e-60 204.6 5.4 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein P4Ha_N PF08336.6 EGG41929.1 - 0.022 14.5 1.2 0.12 12.1 0.7 2.0 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UbiD PF01977.11 EGG41929.1 - 0.039 12.4 0.0 0.049 12.0 0.0 1.2 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase HD_3 PF13023.1 EGG41929.1 - 0.054 13.2 5.1 0.16 11.7 3.5 1.7 1 1 0 1 1 1 0 HD domain TraF_2 PF13729.1 EGG41929.1 - 0.075 11.8 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF3566 PF12089.3 EGG41929.1 - 0.13 12.3 0.1 0.13 12.3 0.0 2.1 1 1 1 2 2 2 0 Transmembrane domain of unknown function (DUF3566) ABC2_membrane_4 PF12730.2 EGG41929.1 - 0.15 11.1 9.3 0.23 10.5 6.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CesA PF11439.3 EGG41929.1 - 0.2 11.5 1.3 1.5 8.8 0.9 2.2 1 1 0 1 1 1 0 Type III secretion system filament chaperone CesA Rho_Binding PF08912.6 EGG41929.1 - 0.27 11.5 1.6 8.6 6.7 0.1 2.7 3 0 0 3 3 3 0 Rho Binding EMP24_GP25L PF01105.19 EGG41929.1 - 3.9 7.1 7.5 0.17 11.6 0.1 2.3 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Usp PF00582.21 EGG41931.1 - 5.4e-22 78.4 0.0 6.7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Transaldolase PF00923.14 EGG41932.1 - 3.9e-61 206.6 0.0 2.9e-60 203.8 0.0 2.1 1 1 0 1 1 1 1 Transaldolase Transket_pyr PF02779.19 EGG41933.1 - 2.2e-30 105.4 0.0 3.2e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGG41933.1 - 3.4e-29 101.2 0.0 5.9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 EGG41934.1 - 1e-63 215.1 0.5 3.3e-62 210.2 0.4 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Ribul_P_3_epim PF00834.14 EGG41934.1 - 4.8e-49 166.2 0.0 6.8e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DXP_synthase_N PF13292.1 EGG41934.1 - 1.5e-05 24.0 0.0 0.00027 19.9 0.0 2.5 2 1 1 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EGG41934.1 - 2.9e-05 23.6 0.0 6.6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EGG41934.1 - 3e-05 22.9 0.1 5.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component XFP_N PF09364.5 EGG41934.1 - 6.3e-05 21.7 0.3 0.00062 18.4 0.0 2.1 2 0 0 2 2 2 1 XFP N-terminal domain DUF393 PF04134.7 EGG41935.1 - 0.011 16.7 0.0 0.016 16.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF393 Peptidase_M17 PF00883.16 EGG41936.1 - 5.2e-113 377.0 0.1 6.8e-113 376.6 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EGG41936.1 - 4.5e-18 65.1 0.2 2.2e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Seryl_tRNA_N PF02403.17 EGG41937.1 - 0.068 13.1 0.7 0.073 13.0 0.5 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPD52 PF04201.10 EGG41937.1 - 0.083 12.6 1.0 0.11 12.2 0.7 1.3 1 1 0 1 1 1 0 Tumour protein D52 family DUF2051 PF09738.4 EGG41937.1 - 0.11 11.8 1.6 0.39 9.9 1.1 1.7 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) ABC_tran PF00005.22 EGG41939.1 - 6e-40 136.7 0.6 7e-19 68.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EGG41939.1 - 2.5e-11 42.9 3.0 2.5e-11 42.9 2.1 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EGG41939.1 - 9.9e-10 38.8 10.2 0.02 14.8 0.0 4.5 3 2 1 4 4 3 3 AAA domain Fer4 PF00037.22 EGG41939.1 - 1.2e-08 34.2 11.1 3e-08 32.9 3.7 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.14 EGG41939.1 - 8e-08 31.7 8.9 0.0014 17.8 0.8 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4_6 PF12837.2 EGG41939.1 - 1.4e-07 31.0 15.7 4.2e-07 29.5 3.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.2 EGG41939.1 - 3.7e-06 26.5 12.0 1.1e-05 24.9 2.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain DUF258 PF03193.11 EGG41939.1 - 1.2e-05 24.5 0.4 0.016 14.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EGG41939.1 - 1.5e-05 24.2 7.3 0.57 9.1 0.0 4.2 2 2 2 4 4 4 2 AAA ATPase domain Fer4_7 PF12838.2 EGG41939.1 - 1.6e-05 25.1 11.0 3.7e-05 24.0 7.7 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGG41939.1 - 0.0001 22.1 12.2 0.00017 21.3 8.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_29 PF13555.1 EGG41939.1 - 0.0002 20.8 0.2 0.045 13.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.17 EGG41939.1 - 0.00032 19.6 0.1 0.48 9.2 0.1 3.1 3 0 0 3 3 3 2 NB-ARC domain Fer4_10 PF13237.1 EGG41939.1 - 0.00042 20.0 2.2 0.00042 20.0 1.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGG41939.1 - 0.0008 19.6 11.2 0.0018 18.5 7.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Miro PF08477.8 EGG41939.1 - 0.0011 19.4 0.1 0.16 12.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 EGG41939.1 - 0.0025 17.6 0.4 5 7.1 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_3 PF12798.2 EGG41939.1 - 0.0067 16.9 5.4 0.0067 16.9 3.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain MMR_HSR1 PF01926.18 EGG41939.1 - 0.0093 15.9 2.9 0.98 9.3 0.6 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Fer4_4 PF12800.2 EGG41939.1 - 0.0099 16.1 3.4 0.0099 16.1 2.3 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.1 EGG41939.1 - 0.019 15.0 4.7 0.041 13.9 3.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_16 PF13191.1 EGG41939.1 - 0.02 14.9 2.1 0.53 10.2 0.1 3.2 2 2 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EGG41939.1 - 0.02 14.3 0.1 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 EGG41939.1 - 0.04 14.2 4.5 0.097 13.0 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.1 EGG41939.1 - 0.043 13.7 1.8 1.6 8.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain Fer4_15 PF13459.1 EGG41939.1 - 0.048 14.2 1.0 0.048 14.2 0.7 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 EGG41939.1 - 0.059 14.1 13.0 0.73 10.6 9.1 2.4 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain RNA_helicase PF00910.17 EGG41939.1 - 0.06 13.5 0.2 2.1 8.5 0.1 2.9 2 1 0 2 2 2 0 RNA helicase AAA PF00004.24 EGG41939.1 - 0.083 13.0 0.5 7.6 6.7 0.0 3.1 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EGG41939.1 - 0.76 10.0 10.2 5.1 7.3 1.4 3.2 2 2 0 2 2 2 0 AAA domain Fer4_18 PF13746.1 EGG41939.1 - 3.2 8.2 11.0 0.26 11.7 2.9 2.3 1 1 0 2 2 2 0 4Fe-4S dicluster domain Met_10 PF02475.11 EGG41940.1 - 3.4e-63 212.8 0.2 4.2e-63 212.5 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EGG41940.1 - 1.4e-07 31.1 0.1 2.4e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG41940.1 - 6.9e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG41940.1 - 1.6e-06 28.6 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGG41940.1 - 2.2e-06 27.0 0.1 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EGG41940.1 - 9.6e-06 25.2 0.1 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EGG41940.1 - 4.5e-05 22.8 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TRM PF02005.11 EGG41940.1 - 0.0002 20.4 0.0 0.00025 20.0 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Cons_hypoth95 PF03602.10 EGG41940.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.4 EGG41940.1 - 0.012 15.0 0.1 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DNA_methylase PF00145.12 EGG41940.1 - 0.017 14.2 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase ADH_zinc_N PF00107.21 EGG41940.1 - 0.031 13.8 0.0 0.15 11.6 0.0 2.3 3 1 0 3 3 3 0 Zinc-binding dehydrogenase FtsJ PF01728.14 EGG41940.1 - 0.039 13.9 0.1 0.12 12.3 0.1 1.6 1 1 1 2 2 2 0 FtsJ-like methyltransferase MethyltransfD12 PF02086.10 EGG41940.1 - 0.041 13.3 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_11 PF08241.7 EGG41940.1 - 0.07 13.6 0.0 0.17 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF2613 PF11021.3 EGG41941.1 - 0.028 14.1 0.3 0.043 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF1469 PF07332.6 EGG41941.1 - 0.23 11.1 4.7 0.27 10.9 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF2628 PF10947.3 EGG41941.1 - 0.23 11.2 1.8 0.23 11.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DUF2985 PF11204.3 EGG41941.1 - 0.47 10.2 3.1 0.59 9.9 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2985) Claudin_2 PF13903.1 EGG41941.1 - 1.4 8.6 4.8 1.5 8.4 3.3 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1049 PF06305.6 EGG41941.1 - 1.7 8.1 6.3 0.73 9.3 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Acetyltransf_1 PF00583.19 EGG41942.1 - 2.9e-17 62.4 0.2 4.2e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGG41942.1 - 1e-09 38.0 0.2 4.1e-09 36.0 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EGG41942.1 - 2.4e-09 37.2 0.4 3.7e-09 36.6 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGG41942.1 - 3.7e-09 36.7 0.0 5.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGG41942.1 - 9.9e-06 25.5 0.1 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGG41942.1 - 0.0002 21.3 0.1 0.00026 20.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGG41942.1 - 0.00085 19.5 0.1 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGG41942.1 - 0.0033 17.2 0.0 0.0077 16.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGG41942.1 - 0.022 14.6 0.1 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M50 PF02163.17 EGG41943.1 - 1.2e-17 63.5 7.7 1.6e-16 59.8 4.4 2.6 2 1 0 2 2 2 1 Peptidase family M50 Pribosyltran PF00156.22 EGG41945.1 - 2.7e-13 49.7 0.2 6.5e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 EGG41945.1 - 0.00024 20.4 0.2 0.00052 19.3 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase UPRTase PF14681.1 EGG41945.1 - 0.00043 19.5 0.2 0.00059 19.1 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SmpB PF01668.13 EGG41945.1 - 0.012 15.3 0.1 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 SmpB protein TENA_THI-4 PF03070.11 EGG41946.1 - 8.3e-14 51.8 0.7 1e-13 51.5 0.5 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.1 EGG41946.1 - 5.1e-06 26.5 0.0 4e-05 23.7 0.0 2.1 1 1 1 2 2 2 1 Iron-containing redox enzyme polyprenyl_synt PF00348.12 EGG41947.1 - 5.3e-42 143.4 0.1 7.9e-42 142.8 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Oxidored_q1 PF00361.15 EGG41948.1 - 4e-60 203.3 21.6 4e-60 203.3 15.0 2.9 4 0 0 4 4 4 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1 PF00361.15 EGG41949.1 - 9.4e-57 192.3 24.9 2.8e-52 177.6 16.9 3.4 3 1 0 3 3 3 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 EGG41949.1 - 1.3e-11 43.9 1.5 6.2e-11 41.7 1.1 2.2 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q1_C PF01010.14 EGG41949.1 - 0.00023 20.7 0.3 0.00048 19.6 0.2 1.5 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Oxidored_q1 PF00361.15 EGG41950.1 - 3.7e-61 206.7 25.4 3.7e-61 206.7 17.6 2.9 4 0 0 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 EGG41950.1 - 0.042 13.4 0.1 0.042 13.4 0.1 2.6 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.19 EGG41951.1 - 4.6e-23 80.6 3.8 5.5e-23 80.3 2.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Oxidored_q3 PF00499.15 EGG41952.1 - 3.1e-21 75.6 12.5 3.8e-21 75.3 8.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4040 PF13244.1 EGG41952.1 - 0.0041 17.0 8.7 0.0041 17.0 6.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4040) MIG-14_Wnt-bd PF06664.7 EGG41952.1 - 0.048 12.4 3.7 0.065 12.0 2.5 1.4 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion NfeD PF01957.13 EGG41952.1 - 0.79 9.8 13.0 0.15 12.1 5.5 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 EGG41952.1 - 1.4 8.2 7.0 0.44 9.9 0.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UPF0104 PF03706.8 EGG41952.1 - 2.1 7.5 15.6 15 4.7 11.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) Fer4 PF00037.22 EGG41953.1 - 6.2e-12 44.5 10.8 2.6e-09 36.2 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 EGG41953.1 - 6.7e-10 38.6 16.7 1.4e-06 27.9 6.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGG41953.1 - 1.3e-09 38.2 9.8 2.1e-09 37.5 6.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGG41953.1 - 3.7e-09 36.3 19.3 1.7e-06 27.7 7.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGG41953.1 - 2.5e-08 33.3 10.5 6.8e-05 22.5 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.1 EGG41953.1 - 3.9e-07 30.2 8.6 6.8e-07 29.4 6.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGG41953.1 - 1.6e-06 28.0 17.9 6e-05 22.9 6.8 1.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.1 EGG41953.1 - 3.2e-06 27.3 7.1 0.0033 17.7 0.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGG41953.1 - 5.1e-06 26.1 1.8 5.1e-06 26.1 1.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.1 EGG41953.1 - 1.6e-05 25.5 17.3 0.00071 20.2 6.6 1.8 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 EGG41953.1 - 3e-05 23.9 9.1 0.0024 18.0 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 EGG41953.1 - 0.00044 20.7 4.6 0.096 13.2 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 EGG41953.1 - 0.0023 18.3 4.5 0.23 11.8 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 EGG41953.1 - 0.0025 18.2 11.7 0.004 17.5 0.7 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.2 EGG41953.1 - 0.0031 17.9 17.3 0.0057 17.1 2.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain DUF2607 PF10795.4 EGG41953.1 - 0.033 14.0 0.4 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) NADHdh PF00146.16 EGG41954.1 - 1.4e-80 270.6 16.0 2.1e-80 270.1 11.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase Complex1_49kDa PF00346.14 EGG41955.1 - 8.5e-58 195.4 0.0 1.2e-46 158.9 0.0 2.2 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ribosomal_S5_C PF03719.10 EGG41955.1 - 0.16 11.2 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain DUF3195 PF11424.3 EGG41955.1 - 0.18 12.0 1.4 1.2 9.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3195) Complex1_30kDa PF00329.14 EGG41956.1 - 9.7e-29 99.6 0.2 4.2e-28 97.6 0.2 1.8 1 1 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Alkyl_sulf_dimr PF14863.1 EGG41956.1 - 0.069 13.3 0.0 3.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Oxidored_q6 PF01058.17 EGG41957.1 - 7e-25 87.1 0.1 9.8e-25 86.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.14 EGG41958.1 - 1e-15 57.3 0.9 1.2e-15 57.1 0.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 AhpC-TSA PF00578.16 EGG41959.1 - 8.5e-34 115.9 0.0 9.9e-34 115.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG41959.1 - 9.5e-22 77.1 0.0 1.1e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EGG41959.1 - 0.013 15.1 0.1 0.019 14.5 0.1 1.3 1 1 0 1 1 1 0 SCO1/SenC Biotin_lipoyl PF00364.17 EGG41960.1 - 4.3e-17 61.5 4.7 8.3e-17 60.5 3.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EGG41960.1 - 1.6e-10 40.5 2.5 1.5e-09 37.3 0.2 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 EGG41960.1 - 3.2e-05 23.3 1.6 0.00028 20.3 0.2 2.0 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EGG41960.1 - 4e-05 23.9 1.2 0.082 13.2 0.0 2.7 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_2 PF12700.2 EGG41960.1 - 0.0014 17.8 0.2 0.0014 17.8 0.1 3.0 2 1 1 3 3 3 2 HlyD family secretion protein GCV_H PF01597.14 EGG41960.1 - 0.0037 16.9 0.6 0.0091 15.6 0.4 1.8 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EGG41960.1 - 0.0052 16.4 1.7 0.011 15.4 1.2 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Big_3_3 PF13750.1 EGG41960.1 - 0.0082 15.5 1.8 0.022 14.2 0.4 2.0 1 1 1 2 2 2 1 Bacterial Ig-like domain (group 3) DUF2118 PF09891.4 EGG41960.1 - 0.022 14.4 1.2 0.03 14.0 0.1 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) QRPTase_N PF02749.11 EGG41960.1 - 0.028 14.2 0.1 0.082 12.7 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.17 EGG41960.1 - 0.043 13.8 1.8 0.59 10.2 0.1 2.7 2 1 1 3 3 3 0 Peptidase family M23 NQRA PF05896.6 EGG41960.1 - 0.047 12.8 0.3 0.071 12.2 0.2 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF4164 PF13747.1 EGG41960.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CPSase_L_D2 PF02786.12 EGG41961.1 - 5.1e-69 231.7 0.0 7.6e-69 231.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGG41961.1 - 8.1e-41 138.5 0.1 1.5e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGG41961.1 - 2.5e-32 111.0 0.0 5.2e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EGG41961.1 - 2.5e-17 63.2 0.0 4.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG41961.1 - 4.6e-12 45.3 0.0 7.1e-11 41.4 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGG41961.1 - 4.1e-10 39.2 0.1 8.9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EGG41961.1 - 1.6e-09 37.5 0.0 1.4e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG41961.1 - 8.3e-08 31.8 0.2 2.4e-07 30.3 0.2 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGG41961.1 - 7.7e-07 29.1 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EGG41961.1 - 0.07 12.6 0.3 0.26 10.7 0.0 2.0 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Carboxyl_trans PF01039.17 EGG41962.1 - 4.1e-186 619.1 0.0 4.6e-186 618.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGG41962.1 - 1.5e-06 27.5 0.0 3.1e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Myticin-prepro PF10690.4 EGG41963.1 - 0.086 12.8 6.2 0.12 12.3 4.3 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel AAA PF00004.24 EGG41964.1 - 1.2e-12 48.1 0.0 3.2e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGG41964.1 - 2.7e-11 42.8 0.5 0.00014 20.7 0.0 2.3 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EGG41964.1 - 2e-08 33.5 0.0 4.4e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGG41964.1 - 0.00021 22.0 0.8 0.0007 20.4 0.1 2.2 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGG41964.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGG41964.1 - 0.00052 18.8 0.0 0.00088 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EGG41964.1 - 0.00082 19.5 0.2 0.082 13.0 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EGG41964.1 - 0.0035 17.0 0.1 0.032 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGG41964.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EGG41964.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EGG41964.1 - 0.016 15.4 0.0 0.059 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGG41964.1 - 0.026 13.6 0.2 0.1 11.7 0.0 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGG41964.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGG41964.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 EGG41964.1 - 0.036 12.9 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 EGG41964.1 - 0.05 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 EGG41964.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGG41964.1 - 0.085 12.8 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EGG41964.1 - 0.35 10.4 1.6 2.8 7.5 0.0 2.8 3 1 1 4 4 4 0 NACHT domain Inositol_P PF00459.20 EGG41966.1 - 8.4e-31 107.2 0.0 9.2e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 EGG41966.1 - 2.1e-06 26.8 0.1 6.6e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase NAD_binding_1 PF00175.16 EGG41967.1 - 2.3e-13 50.6 0.0 4.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGG41967.1 - 3.7e-10 39.7 0.0 6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGG41967.1 - 0.029 14.2 0.2 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF1059 PF06348.6 EGG41968.1 - 3.8e-06 26.6 0.2 4.2e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Fer2_BFD PF04324.10 EGG41968.1 - 0.052 13.6 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain GlutR_N PF05201.10 EGG41969.1 - 2.6e-30 105.0 0.0 3.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 EGG41969.1 - 6.2e-13 49.0 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF498 PF04430.9 EGG41969.1 - 0.0017 17.8 0.2 2.3 7.7 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF498/DUF598) NAD_binding_7 PF13241.1 EGG41969.1 - 0.002 18.3 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding K_oxygenase PF13434.1 EGG41969.1 - 0.053 12.4 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3896 PF13035.1 EGG41970.1 - 0.012 15.6 0.4 0.03 14.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) MEF2_binding PF09047.5 EGG41970.1 - 0.032 13.8 11.9 0.34 10.5 0.7 3.0 2 0 0 2 2 2 0 MEF2 binding DUF512 PF04459.7 EGG41970.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Mitofilin PF09731.4 EGG41970.1 - 0.26 9.8 12.5 0.31 9.6 8.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Herpes_UL17 PF04559.7 EGG41970.1 - 0.27 9.7 4.2 0.32 9.5 2.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein CDC27 PF09507.5 EGG41970.1 - 2.7 7.1 15.6 3.6 6.6 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_C27 PF05407.7 EGG41970.1 - 4 7.1 8.8 5.8 6.6 6.1 1.1 1 0 0 1 1 1 0 Rubella virus endopeptidase DivIVA PF05103.8 EGG41970.1 - 9.1 6.3 16.2 20 5.2 0.0 2.3 2 0 0 2 2 2 0 DivIVA protein Lyase_1 PF00206.15 EGG41971.1 - 6.8e-51 173.2 0.1 2.2e-49 168.3 0.0 2.2 2 0 0 2 2 2 2 Lyase ASL_C2 PF14698.1 EGG41971.1 - 4.7e-16 58.6 0.0 8.6e-15 54.5 0.0 2.7 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF59 PF01883.14 EGG41972.1 - 2.8e-13 49.6 0.1 3.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF59 HMA PF00403.21 EGG41972.1 - 0.09 12.9 0.6 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Heavy-metal-associated domain Fer2_3 PF13085.1 EGG41973.1 - 3.4e-30 104.0 0.6 5.9e-30 103.3 0.0 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 EGG41973.1 - 2.4e-12 46.6 4.9 5e-12 45.6 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGG41973.1 - 4.5e-11 43.0 6.4 2.6e-09 37.3 0.3 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EGG41973.1 - 2e-10 40.8 10.4 1.5e-08 34.8 1.3 2.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGG41973.1 - 1.2e-08 35.0 2.4 1.2e-08 35.0 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGG41973.1 - 1.4e-08 34.4 2.5 1.4e-08 34.4 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGG41973.1 - 3.4e-08 33.7 14.3 7.3e-07 29.4 3.3 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGG41973.1 - 3.2e-05 23.5 1.0 3.2e-05 23.5 0.7 3.3 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4 PF00037.22 EGG41973.1 - 3.4e-05 23.2 1.0 3.4e-05 23.2 0.7 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer2 PF00111.22 EGG41973.1 - 0.00017 21.2 0.1 0.00017 21.2 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_6 PF12837.2 EGG41973.1 - 0.0023 17.7 1.5 0.0023 17.7 1.0 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_16 PF13484.1 EGG41973.1 - 0.0035 18.0 5.5 0.0035 18.0 3.8 2.4 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 EGG41973.1 - 0.087 13.2 2.0 0.087 13.2 1.4 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.2 EGG41973.1 - 0.15 12.6 0.9 0.15 12.6 0.6 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_21 PF14697.1 EGG41973.1 - 0.36 10.7 13.4 0.24 11.3 5.6 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EGG41973.1 - 4.9 7.7 9.3 0.53 10.8 0.1 2.8 3 0 0 3 3 2 0 4Fe-4S single cluster domain Sdh_cyt PF01127.17 EGG41974.1 - 1.1e-08 34.9 2.2 1.2e-08 34.7 1.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4405 PF14358.1 EGG41974.1 - 0.033 14.3 3.5 0.85 9.8 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Cytochrom_B_N_2 PF13631.1 EGG41974.1 - 0.055 13.2 0.7 0.088 12.5 0.5 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_N PF00033.14 EGG41974.1 - 2.7 7.3 6.9 13 5.0 4.8 2.0 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB CcmD PF04995.9 EGG41974.1 - 4.5 7.0 6.0 4.3 7.1 0.2 2.6 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Sdh_cyt PF01127.17 EGG41975.1 - 7.1e-08 32.3 3.7 1.2e-07 31.5 2.4 1.5 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FAD_binding_2 PF00890.19 EGG41976.1 - 1.6e-98 330.2 0.1 2e-98 329.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGG41976.1 - 2.7e-40 137.2 0.5 4.6e-40 136.4 0.3 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EGG41976.1 - 1.5e-05 25.0 6.0 0.0049 16.7 4.2 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGG41976.1 - 0.00019 20.6 0.1 0.0024 17.0 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGG41976.1 - 0.00068 18.6 0.0 0.037 12.8 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 EGG41976.1 - 0.0039 16.1 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGG41976.1 - 0.014 14.5 0.1 0.051 12.6 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EGG41976.1 - 0.018 13.9 0.1 0.038 12.8 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EGG41976.1 - 0.034 12.6 0.4 2.1 6.7 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein PadR PF03551.9 EGG41977.1 - 2.9e-10 39.7 0.1 5.3e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.1 EGG41977.1 - 7.3e-06 25.7 0.3 7.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix Mrr_N PF14338.1 EGG41977.1 - 0.019 15.0 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Mrr N-terminal domain DisA-linker PF10635.4 EGG41977.1 - 0.071 12.6 0.5 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region HemN_C PF06969.11 EGG41977.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.7 1 1 0 1 1 1 0 HemN C-terminal domain PEP_mutase PF13714.1 EGG41978.1 - 1.1e-53 181.9 0.1 1.3e-53 181.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EGG41978.1 - 4.3e-17 61.5 0.1 2.8e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 Isocitrate lyase family Alba PF01918.16 EGG41979.1 - 2.6e-11 42.9 0.1 3.6e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 EGG41979.1 - 0.0055 16.3 0.6 0.32 10.6 0.0 2.2 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P DUF500 PF04366.7 EGG41979.1 - 0.037 13.4 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF500) Waikav_capsid_1 PF12264.3 EGG41979.1 - 0.049 12.9 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Waikavirus capsid protein 1 HEAT_2 PF13646.1 EGG41980.1 - 3.5e-14 52.8 0.5 3.1e-09 36.9 0.1 2.9 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 EGG41980.1 - 1.9e-10 39.9 0.0 0.0099 15.8 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EGG41980.1 - 2.9e-06 27.5 0.0 0.22 12.0 0.0 3.6 3 1 1 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EGG41980.1 - 1.7e-05 24.6 0.6 0.46 10.5 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EGG41980.1 - 0.00038 18.9 2.3 0.0017 16.7 1.6 1.8 1 1 0 1 1 1 1 Adaptin N terminal region DUF2435 PF10363.4 EGG41980.1 - 0.00071 19.4 0.2 0.25 11.2 0.0 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) DNA_pol3_delta PF06144.8 EGG41980.1 - 0.00075 19.0 0.5 0.13 11.7 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit ERAP1_C PF11838.3 EGG41980.1 - 0.0013 18.0 0.3 0.33 10.1 0.0 2.3 1 1 1 2 2 2 2 ERAP1-like C-terminal domain Cnd1 PF12717.2 EGG41980.1 - 0.0018 18.1 0.6 0.29 10.9 0.0 2.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EGG41980.1 - 0.02 14.7 1.1 1 9.3 0.0 3.7 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.1 EGG41980.1 - 0.022 14.2 0.1 7 6.0 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) HEAT_PBS PF03130.11 EGG41980.1 - 0.034 14.6 0.0 21 5.9 0.0 3.8 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EGG41980.1 - 0.035 13.4 0.1 0.12 11.7 0.1 2.0 1 1 0 1 1 1 0 CLASP N terminal ArsC PF03960.10 EGG41980.1 - 0.16 12.0 4.0 0.28 11.2 0.1 2.6 2 1 0 2 2 2 0 ArsC family Rep_2 PF01719.12 EGG41980.1 - 8 5.9 7.3 2.7 7.4 1.2 2.4 2 1 1 3 3 3 0 Plasmid replication protein NAD_binding_1 PF00175.16 EGG41981.1 - 8.2e-15 55.3 0.0 1.6e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGG41981.1 - 4e-11 42.8 0.0 6.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGG41981.1 - 0.038 13.9 0.1 0.13 12.1 0.1 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain CTP_transf_2 PF01467.21 EGG41982.1 - 0.0091 16.0 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase Aminotran_4 PF01063.14 EGG41983.1 - 3.5e-40 137.9 0.0 4.2e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV GFO_IDH_MocA PF01408.17 EGG41984.1 - 4.5e-25 88.4 0.0 7.8e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGG41984.1 - 5.9e-08 32.5 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EGG41984.1 - 0.016 15.5 0.1 0.049 13.9 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M73 PF12389.3 EGG41984.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Trm112p PF03966.11 EGG41985.1 - 5.7e-08 33.0 0.7 1.3e-07 31.8 0.2 1.8 2 1 0 2 2 2 1 Trm112p-like protein Cys_rich_KTR PF14205.1 EGG41985.1 - 0.052 13.0 0.4 0.11 11.9 0.3 1.6 1 1 0 1 1 1 0 Cysteine-rich KTR zf-ribbon_3 PF13248.1 EGG41985.1 - 0.062 12.5 0.2 0.12 11.5 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Hexapep PF00132.19 EGG41986.1 - 2.8e-28 96.1 18.0 9.9e-11 40.6 0.5 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGG41986.1 - 1.6e-18 65.9 12.7 2.9e-11 42.7 2.5 4.6 5 1 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase Peptidase_S49_N PF08496.5 EGG41987.1 - 0.13 11.9 0.4 0.16 11.7 0.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sdh_cyt PF01127.17 EGG41987.1 - 0.31 10.8 4.2 0.37 10.6 2.9 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sec62 PF03839.11 EGG41987.1 - 0.45 9.8 6.8 0.47 9.8 4.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 AA_permease PF00324.16 EGG41987.1 - 2.2 6.5 10.8 2.2 6.4 7.5 1.0 1 0 0 1 1 1 0 Amino acid permease DUF4212 PF13937.1 EGG41987.1 - 2.4 8.1 5.8 3 7.9 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) Glycos_transf_4 PF00953.16 EGG41988.1 - 2.9e-25 88.9 15.8 2.9e-25 88.9 10.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 Big_3_3 PF13750.1 EGG41988.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DEAD PF00270.24 EGG41989.1 - 1.5e-28 99.4 0.7 3.3e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HHH_5 PF14520.1 EGG41989.1 - 9e-13 48.1 0.7 3e-12 46.5 0.5 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.26 EGG41989.1 - 6.2e-11 42.0 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG41989.1 - 2.1e-08 34.2 0.0 4.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_2 PF12826.2 EGG41989.1 - 1e-06 28.5 1.3 8.9e-05 22.2 0.0 3.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.4 EGG41989.1 - 1.8e-05 24.1 0.0 4.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Sec63 PF02889.11 EGG41989.1 - 0.00021 20.6 0.1 0.00021 20.6 0.1 1.8 2 0 0 2 2 2 1 Sec63 Brl domain DUF4332 PF14229.1 EGG41989.1 - 0.0039 17.1 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) Arch_ATPase PF01637.13 EGG41989.1 - 0.0078 15.9 3.4 0.016 14.8 0.2 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 EGG41989.1 - 0.018 14.4 0.0 0.24 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zot PF05707.7 EGG41989.1 - 0.023 14.1 0.0 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) T2SE PF00437.15 EGG41989.1 - 0.039 12.8 0.0 0.078 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MCM PF00493.18 EGG41990.1 - 2.2e-126 421.1 0.1 3e-126 420.7 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGG41990.1 - 3.6e-15 56.5 0.5 2.2e-14 54.0 0.1 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EGG41990.1 - 1.2e-06 28.3 0.0 2e-05 24.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGG41990.1 - 2.4e-06 26.8 0.1 0.00019 20.6 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGG41990.1 - 0.00098 18.7 0.0 0.0032 17.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sld5 PF05916.6 EGG41991.1 - 2.3e-09 37.5 1.1 2.9e-09 37.1 0.8 1.2 1 0 0 1 1 1 1 GINS complex protein DNA_pol3_delta2 PF13177.1 EGG41992.1 - 5.8e-17 61.8 1.8 5e-15 55.5 0.2 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 EGG41992.1 - 9.7e-13 48.4 0.9 1.9e-12 47.5 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EGG41992.1 - 9.8e-12 44.6 2.5 1.4e-11 44.2 0.4 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.10 EGG41992.1 - 6.7e-09 34.9 0.2 0.00055 18.7 0.1 2.4 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EGG41992.1 - 4.4e-06 26.6 0.0 9.2e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG41992.1 - 1e-05 25.7 0.9 0.039 14.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.8 EGG41992.1 - 2.2e-05 24.0 1.0 5.3e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EGG41992.1 - 2.9e-05 23.2 0.0 0.00011 21.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EGG41992.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGG41992.1 - 0.0005 20.1 0.1 0.057 13.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain DEAD PF00270.24 EGG41992.1 - 0.0034 16.8 0.6 0.26 10.7 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EGG41992.1 - 0.0065 15.6 0.0 0.5 9.4 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EGG41992.1 - 0.0076 15.7 2.2 0.6 9.5 0.1 2.5 1 1 0 2 2 2 1 AAA-like domain PhoH PF02562.11 EGG41992.1 - 0.0082 15.3 0.2 1.8 7.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EGG41992.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EGG41992.1 - 0.025 14.4 0.3 0.22 11.3 0.2 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EGG41992.1 - 0.028 14.7 0.9 0.29 11.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain PTPlike_phytase PF14566.1 EGG41992.1 - 0.039 13.9 0.2 0.14 12.2 0.0 2.0 2 1 0 2 2 2 0 Inositol hexakisphosphate AAA_5 PF07728.9 EGG41992.1 - 0.077 12.7 0.6 0.93 9.2 0.4 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) HATPase_c PF02518.21 EGG41993.1 - 5.5e-24 84.0 0.1 1.6e-23 82.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3068 PF11271.3 EGG41993.1 - 1.1e-13 50.8 0.2 1.8e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3068) HisKA PF00512.20 EGG41993.1 - 7.3e-09 35.5 0.1 2.3e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG41993.1 - 9.2e-09 34.9 0.8 5.7e-07 29.1 0.0 2.6 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 EGG41993.1 - 0.00016 21.3 0.1 0.00044 19.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG41993.1 - 0.0024 17.6 0.0 0.0064 16.2 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Fer4_8 PF13183.1 EGG41995.1 - 6.4e-10 38.9 11.6 2.7e-08 33.7 3.6 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGG41995.1 - 8.6e-10 38.8 1.9 0.00059 20.1 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGG41995.1 - 3e-08 33.4 2.8 0.0012 18.6 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 EGG41995.1 - 3.1e-08 32.8 12.2 0.00022 20.7 1.8 2.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 EGG41995.1 - 9.8e-08 32.1 6.9 3.3e-07 30.4 4.8 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGG41995.1 - 2.5e-07 30.3 8.1 4.8e-06 26.2 6.3 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EGG41995.1 - 1.8e-06 28.2 3.2 3.5e-06 27.2 2.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGG41995.1 - 1.1e-05 25.0 9.7 0.012 15.4 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 EGG41995.1 - 7e-05 23.3 5.0 0.024 15.2 0.1 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_16 PF13484.1 EGG41995.1 - 8.2e-05 23.2 8.2 0.0041 17.8 6.5 2.4 1 1 2 3 3 3 3 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 EGG41995.1 - 0.0001 22.6 8.6 0.00021 21.6 4.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGG41995.1 - 0.00016 21.9 5.1 0.18 12.2 0.2 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_2 PF12797.2 EGG41995.1 - 0.00069 19.3 13.3 0.009 15.8 0.8 2.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.2 EGG41995.1 - 0.0036 17.7 13.8 0.14 12.7 3.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EGG41995.1 - 0.0041 17.3 11.3 0.28 11.6 2.0 2.6 3 0 0 3 3 2 2 4Fe-4S binding domain DUF2761 PF10959.3 EGG41995.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) Fer4_7 PF12838.2 EGG41996.1 - 5.8e-10 39.4 1.9 0.00016 21.9 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 EGG41996.1 - 8.4e-10 37.8 11.9 5.6e-06 25.7 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EGG41996.1 - 1.6e-08 34.4 0.4 0.002 18.1 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGG41996.1 - 3.2e-08 33.7 4.8 9.9e-08 32.1 3.3 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGG41996.1 - 5.4e-07 29.1 12.5 0.00074 19.2 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 EGG41996.1 - 1.1e-06 29.2 4.4 0.00033 21.3 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_15 PF13459.1 EGG41996.1 - 1.5e-06 28.6 4.2 0.0047 17.4 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_10 PF13237.1 EGG41996.1 - 3.7e-06 26.6 20.0 8.4e-05 22.2 6.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGG41996.1 - 4.4e-06 26.3 11.7 0.0065 16.3 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EGG41996.1 - 1.6e-05 25.1 7.5 8e-05 22.9 3.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGG41996.1 - 2.9e-05 23.8 8.9 0.003 17.3 6.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 EGG41996.1 - 4.7e-05 23.3 6.8 0.039 14.2 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 EGG41996.1 - 9.3e-05 22.7 6.4 0.033 14.5 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_17 PF13534.1 EGG41996.1 - 0.00018 21.8 4.8 0.0064 16.8 4.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.1 EGG41996.1 - 0.0011 18.7 0.9 0.53 10.2 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 EGG41996.1 - 0.061 13.9 16.2 0.21 12.2 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain eIF-6 PF01912.13 EGG41997.1 - 2.9e-65 219.1 1.8 3.5e-65 218.8 1.3 1.1 1 0 0 1 1 1 1 eIF-6 family tRNA-synt_His PF13393.1 EGG41998.1 - 5.7e-48 163.5 0.0 7.5e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGG41998.1 - 3.4e-17 62.5 0.1 7.8e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGG41998.1 - 5.9e-10 38.9 0.3 1.7e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 EGG41998.1 - 0.00043 19.5 0.1 0.0012 18.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Hemagglutinin PF00509.13 EGG41998.1 - 0.15 10.1 1.3 0.23 9.5 0.9 1.2 1 0 0 1 1 1 0 Haemagglutinin Helitron_like_N PF14214.1 EGG41999.1 - 0.36 10.5 0.1 0.36 10.5 0.0 2.4 2 1 0 2 2 2 0 Helitron helicase-like domain at N-terminus Archease PF01951.11 EGG42000.1 - 2.8e-32 111.5 1.6 3.1e-32 111.4 1.1 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) RdgC PF04381.7 EGG42000.1 - 0.013 14.4 0.4 0.016 14.1 0.3 1.1 1 0 0 1 1 1 0 Putative exonuclease, RdgC HycA_repressor PF11046.3 EGG42000.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons AsnC_trans_reg PF01037.16 EGG42001.1 - 1.8e-13 49.9 0.2 2e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 AsnC family Pneumovirus_M2 PF06436.6 EGG42001.1 - 0.028 13.6 0.2 0.03 13.5 0.1 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) GYD PF08734.6 EGG42001.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 GYD domain Copper-bind PF00127.15 EGG42002.1 - 1.4e-07 31.6 0.1 4.2e-06 26.9 0.1 2.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EGG42002.1 - 9.2e-06 25.5 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Calreticulin PF00262.13 EGG42002.1 - 7.9e-05 21.4 23.1 0.0051 15.5 7.5 2.2 1 1 1 2 2 2 2 Calreticulin family Response_reg PF00072.19 EGG42004.1 - 3e-18 65.8 0.3 3.5e-18 65.6 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Thioredoxin_8 PF13905.1 EGG42004.1 - 0.01 15.9 0.1 0.067 13.3 0.1 1.9 1 1 1 2 2 2 0 Thioredoxin-like HATPase_c PF02518.21 EGG42005.1 - 4.1e-23 81.2 0.4 1.4e-22 79.4 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3068 PF11271.3 EGG42005.1 - 2.2e-14 53.2 0.0 6.3e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3068) HisKA PF00512.20 EGG42005.1 - 3.6e-11 42.9 0.0 6.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG42005.1 - 5.1e-10 38.9 0.5 1.2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 EGG42005.1 - 7.7e-06 25.6 0.3 1.7e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG42005.1 - 0.0034 17.1 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF1312 PF07009.6 EGG42005.1 - 0.39 10.5 6.3 0.24 11.2 0.6 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1312) DUF3240 PF11582.3 EGG42006.1 - 9.6e-05 22.2 0.0 0.0003 20.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3240) P-II PF00543.17 EGG42006.1 - 0.00076 19.9 0.1 0.00084 19.7 0.1 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF190 PF02641.10 EGG42006.1 - 0.0097 15.7 0.3 0.012 15.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 DUF897 PF05982.7 EGG42007.1 - 2.8e-82 276.1 22.2 3.3e-82 275.9 15.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF897) DPM3 PF08285.6 EGG42007.1 - 0.056 13.2 0.2 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1059 PF06348.6 EGG42008.1 - 0.00023 20.8 0.1 0.00034 20.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Lactamase_B_5 PF14597.1 EGG42009.1 - 0.079 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RHH_4 PF13467.1 EGG42009.1 - 0.1 12.5 0.1 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain RHH_1 PF01402.16 EGG42010.1 - 0.0033 17.2 0.0 0.0085 15.9 0.0 1.7 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family HicB PF05534.7 EGG42010.1 - 0.038 13.5 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 HicB family HTH_20 PF12840.2 EGG42011.1 - 4.9e-05 23.0 0.0 6.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 EGG42011.1 - 0.0004 19.9 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.14 EGG42011.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.6 EGG42011.1 - 0.017 14.6 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF742) FUR PF01475.14 EGG42011.1 - 0.084 12.7 0.1 0.097 12.5 0.0 1.3 1 1 0 1 1 1 0 Ferric uptake regulator family Aminotran_3 PF00202.16 EGG42012.1 - 1.5e-105 352.7 0.0 1.9e-105 352.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGG42012.1 - 0.00091 18.2 0.0 0.0019 17.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DUF2931 PF11153.3 EGG42012.1 - 0.035 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) HTH_AsnC-type PF13404.1 EGG42013.1 - 1.4e-13 50.1 0.0 2.6e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EGG42013.1 - 4.4e-13 48.3 0.3 8e-13 47.5 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 EGG42013.1 - 4.7e-12 45.4 0.3 7.2e-12 44.8 0.2 1.3 1 0 0 1 1 1 1 AsnC family HTH_11 PF08279.7 EGG42013.1 - 0.00039 20.0 0.4 0.001 18.6 0.1 1.9 2 0 0 2 2 2 1 HTH domain HTH_27 PF13463.1 EGG42013.1 - 0.00063 20.0 0.1 0.013 15.7 0.0 2.3 1 1 0 2 2 2 1 Winged helix DNA-binding domain ACT_4 PF13291.1 EGG42013.1 - 0.002 18.4 1.2 1.3 9.3 0.2 2.4 2 0 0 2 2 2 2 ACT domain TrmB PF01978.14 EGG42013.1 - 0.0047 16.6 1.4 0.075 12.7 0.1 2.2 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB DDRGK PF09756.4 EGG42013.1 - 0.0058 16.0 2.7 0.012 15.0 0.2 2.1 2 0 0 2 2 2 1 DDRGK domain MarR_2 PF12802.2 EGG42013.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 MarR family DUF2774 PF11242.3 EGG42013.1 - 0.0076 16.2 0.3 0.14 12.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2774) HTH_5 PF01022.15 EGG42013.1 - 0.0079 15.8 0.0 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.1 EGG42013.1 - 0.0083 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.17 EGG42013.1 - 0.009 15.7 0.3 0.023 14.4 0.1 1.8 2 0 0 2 2 1 1 MarR family Sigma70_r4 PF04545.11 EGG42013.1 - 0.012 14.9 0.0 0.033 13.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Mga PF05043.8 EGG42013.1 - 0.018 15.2 0.1 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain NapD PF03927.8 EGG42013.1 - 0.021 14.6 1.4 0.049 13.4 0.8 1.7 1 1 0 1 1 1 0 NapD protein FeoC PF09012.5 EGG42013.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_IclR PF09339.5 EGG42013.1 - 0.03 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF977 PF06163.6 EGG42013.1 - 0.033 13.9 0.2 0.092 12.4 0.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_Mga PF08280.6 EGG42013.1 - 0.035 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_34 PF13601.1 EGG42013.1 - 0.039 13.9 0.2 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_DeoR PF08220.7 EGG42013.1 - 0.04 13.4 0.4 0.16 11.5 0.0 2.0 2 1 1 3 3 3 0 DeoR-like helix-turn-helix domain HTH_9 PF08221.6 EGG42013.1 - 0.058 13.2 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Stk19 PF10494.4 EGG42013.1 - 0.089 12.1 0.3 0.096 12.0 0.2 1.3 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 HMGL-like PF00682.14 EGG42014.1 - 1.2e-61 208.4 0.0 1.6e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 HMGL-like zinc_ribbon_5 PF13719.1 EGG42015.1 - 2e-06 27.2 3.6 0.00094 18.7 0.8 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG42015.1 - 6.4e-06 25.7 4.4 0.0019 17.8 1.2 2.1 1 1 1 2 2 2 2 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EGG42015.1 - 6.9e-05 22.4 0.5 0.15 11.8 0.1 2.1 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.7 EGG42015.1 - 0.00028 20.5 3.2 0.0043 16.7 2.7 2.0 1 1 1 2 2 2 2 PhnA Zinc-Ribbon Prok-RING_1 PF14446.1 EGG42015.1 - 0.0006 19.4 1.9 0.0012 18.4 1.4 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 EGG42015.1 - 0.00094 18.3 0.9 0.027 13.6 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGG42015.1 - 0.0014 17.9 1.0 0.002 17.4 0.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RING_3 PF14369.1 EGG42015.1 - 0.0015 18.4 0.9 0.0023 17.9 0.6 1.3 1 0 0 1 1 1 1 zinc-finger zf-C4_Topoisom PF01396.14 EGG42015.1 - 0.0017 17.8 0.7 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger UPF0547 PF10571.4 EGG42015.1 - 0.0026 17.3 1.8 0.62 9.8 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 HypA PF01155.14 EGG42015.1 - 0.0035 17.0 0.4 0.0039 16.8 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-HYPF PF07503.7 EGG42015.1 - 0.0036 16.6 2.1 0.031 13.6 1.4 2.0 1 1 0 1 1 1 1 HypF finger DNA_RNApol_7kD PF03604.8 EGG42015.1 - 0.0051 16.2 3.1 0.016 14.6 2.1 1.7 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 EGG42015.1 - 0.0096 15.8 2.0 0.015 15.2 1.4 1.3 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.2 EGG42015.1 - 0.01 15.6 1.5 0.021 14.6 1.1 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-CSL PF05207.8 EGG42015.1 - 0.014 14.8 0.4 0.018 14.5 0.2 1.3 1 0 0 1 1 1 0 CSL zinc finger A2L_zn_ribbon PF08792.5 EGG42015.1 - 0.034 13.5 3.5 0.37 10.2 2.4 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain IBR PF01485.16 EGG42015.1 - 0.04 13.7 0.8 0.056 13.3 0.5 1.3 1 0 0 1 1 1 0 IBR domain zinc_ribbon_2 PF13240.1 EGG42015.1 - 0.041 13.3 3.2 1.3 8.6 2.2 2.3 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGG42015.1 - 0.053 13.1 0.3 0.077 12.6 0.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF164 PF02591.10 EGG42015.1 - 0.054 13.3 2.8 1.1 9.1 2.3 2.1 1 1 1 2 2 2 0 Putative zinc ribbon domain C1_1 PF00130.17 EGG42015.1 - 0.058 13.1 0.4 0.11 12.2 0.2 1.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TerY-C PF15616.1 EGG42015.1 - 0.062 13.2 0.6 0.12 12.3 0.4 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain Elf1 PF05129.8 EGG42015.1 - 0.085 12.5 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 EGG42015.1 - 0.088 12.7 0.9 0.84 9.6 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger CpXC PF14353.1 EGG42015.1 - 0.099 12.6 1.8 1.7 8.5 0.1 2.1 1 1 0 2 2 2 0 CpXC protein zf-H2C2_2 PF13465.1 EGG42015.1 - 0.099 12.9 0.3 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain BssC_TutF PF08201.6 EGG42015.1 - 0.1 12.1 0.6 1.3 8.6 0.5 2.0 1 1 1 2 2 2 0 BssC/TutF protein RRN7 PF11781.3 EGG42015.1 - 0.13 11.7 1.3 0.48 9.9 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 XPA_N PF01286.13 EGG42015.1 - 0.25 11.0 1.7 8.3 6.1 0.4 2.1 2 0 0 2 2 2 0 XPA protein N-terminal Lar_restr_allev PF14354.1 EGG42015.1 - 0.41 10.9 2.3 2.1 8.7 1.6 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF1272 PF06906.6 EGG42015.1 - 2.4 8.0 5.0 48 3.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-dskA_traR PF01258.12 EGG42015.1 - 9.5 6.0 7.9 18 5.1 1.4 2.2 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger RimK PF08443.6 EGG42016.1 - 1.1e-45 155.4 0.0 1.3e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 EGG42016.1 - 1.3e-09 37.4 0.0 1.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_4 PF13535.1 EGG42016.1 - 8.4e-09 35.4 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGG42016.1 - 1.6e-07 31.3 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG42016.1 - 6.9e-05 21.7 0.0 0.00045 19.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EGG42016.1 - 0.0057 15.9 0.0 0.0083 15.4 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.1 EGG42016.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 EGG42016.1 - 0.056 12.7 0.0 0.09 12.1 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain Peptidase_M20 PF01546.23 EGG42017.1 - 6.8e-31 107.2 0.1 8.6e-31 106.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGG42017.1 - 2e-11 43.5 0.0 4.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EGG42017.1 - 1e-05 24.4 0.6 0.025 13.3 0.1 2.5 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase TP_methylase PF00590.15 EGG42018.1 - 7.2e-20 71.5 0.0 4e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.8 EGG42018.1 - 7.3e-11 41.6 0.3 8.5e-10 38.1 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF357) Ala_racemase_C PF00842.16 EGG42018.1 - 0.037 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain DUF1661 PF07877.6 EGG42018.1 - 0.41 10.1 1.4 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) CTP_transf_2 PF01467.21 EGG42019.1 - 1.6e-13 50.9 0.0 2.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EGG42019.1 - 0.038 13.6 0.2 0.23 11.0 0.1 2.0 1 1 1 2 2 2 0 FAD synthetase Period_C PF12114.3 EGG42019.1 - 0.045 13.3 0.1 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CTP-dep_RFKase PF01982.11 EGG42020.1 - 4.2e-43 145.8 0.1 6.3e-43 145.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF120 HicB PF05534.7 EGG42020.1 - 0.05 13.1 0.1 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 HicB family EFG_II PF14492.1 EGG42020.1 - 0.12 12.2 0.2 0.5 10.2 0.1 2.0 1 1 0 1 1 1 0 Elongation Factor G, domain II Toprim_4 PF13662.1 EGG42021.1 - 1.3e-06 28.2 0.3 2.9e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.17 EGG42021.1 - 0.032 14.1 0.3 0.092 12.7 0.2 1.9 1 1 0 1 1 1 0 Toprim domain Toprim_2 PF13155.1 EGG42021.1 - 0.051 13.9 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 Toprim-like Copper-fist PF00649.13 EGG42021.1 - 0.18 11.0 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain Fe-S_biosyn PF01521.15 EGG42022.1 - 2.4e-21 75.7 0.0 2.7e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ECH PF00378.15 EGG42023.1 - 5.1e-73 245.2 1.8 5.8e-73 245.0 1.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGG42023.1 - 0.0018 18.4 0.2 0.0032 17.6 0.1 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region DUF3906 PF13046.1 EGG42023.1 - 0.12 12.0 0.2 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) ATP-grasp_5 PF13549.1 EGG42024.1 - 6.7e-68 228.2 0.6 1e-67 227.6 0.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EGG42024.1 - 5.2e-48 162.1 0.1 1.1e-47 161.0 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGG42024.1 - 6.7e-25 87.5 0.0 3.1e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.14 EGG42024.1 - 1.3e-09 38.3 1.6 5.2e-09 36.5 0.1 2.9 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.5 EGG42024.1 - 7.9e-08 31.9 0.8 1.6e-07 30.9 0.6 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGG42024.1 - 0.00016 21.4 0.0 0.00054 19.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EGG42024.1 - 0.017 14.4 0.0 0.043 13.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EGG42024.1 - 0.044 13.2 0.2 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain GATase PF00117.23 EGG42025.1 - 3.9e-24 85.1 0.0 5.5e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG42025.1 - 2.3e-06 27.2 0.1 1.1e-05 25.0 0.0 2.0 2 1 0 2 2 2 1 Peptidase C26 HTS PF04204.11 EGG42025.1 - 1e-05 24.4 0.0 2e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 Homoserine O-succinyltransferase DJ-1_PfpI PF01965.19 EGG42025.1 - 0.035 13.5 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.9 EGG42025.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Toprim PF01751.17 EGG42026.1 - 2.4e-06 27.4 0.1 2.4e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 EGG42026.1 - 3.6e-05 23.6 0.0 7e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Toprim domain Toprim_3 PF13362.1 EGG42026.1 - 0.0017 18.5 0.0 0.002 18.3 0.0 1.1 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 EGG42026.1 - 0.017 15.3 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Toprim-like ELFV_dehydrog PF00208.16 EGG42027.1 - 3.2e-67 226.6 1.9 4.3e-67 226.2 1.3 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EGG42027.1 - 4e-46 155.8 0.0 6.9e-46 155.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Proteasome PF00227.21 EGG42028.1 - 3.5e-48 163.4 1.6 4.3e-48 163.1 1.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGG42028.1 - 5.1e-13 48.0 1.5 3.1e-11 42.3 0.1 2.7 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature Ubie_methyltran PF01209.13 EGG42029.1 - 2.3e-17 62.8 0.0 2.8e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGG42029.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG42029.1 - 9.7e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG42029.1 - 5e-08 32.6 0.0 7.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG42029.1 - 1.7e-07 31.8 0.0 2.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG42029.1 - 2.5e-06 27.7 0.0 3.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG42029.1 - 6e-06 26.6 0.0 1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG42029.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 EGG42029.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EGG42029.1 - 0.082 12.9 0.0 0.39 10.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EGG42030.1 - 1.2e-40 139.3 57.0 1.4e-27 96.3 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EGG42030.1 - 0.0014 17.4 6.0 0.0014 17.4 4.2 2.2 2 0 0 2 2 2 2 PUCC protein MFS_3 PF05977.8 EGG42030.1 - 0.0022 16.2 13.2 0.008 14.3 9.2 1.8 1 1 0 1 1 1 1 Transmembrane secretion effector DUF1228 PF06779.9 EGG42030.1 - 0.02 14.9 8.2 0.023 14.7 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) P-II PF00543.17 EGG42031.1 - 4.3e-20 72.0 0.4 7.3e-20 71.3 0.3 1.3 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II MttA_Hcf106 PF02416.11 EGG42032.1 - 3.5e-07 29.2 0.1 4.6e-07 28.8 0.0 1.3 1 1 0 1 1 1 1 mttA/Hcf106 family Phage_Mu_Gam PF07352.7 EGG42032.1 - 0.00091 18.7 0.2 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein COG2 PF06148.6 EGG42032.1 - 0.04 13.7 0.1 0.061 13.2 0.1 1.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Lip_A_acyltrans PF03279.8 EGG42032.1 - 0.088 11.6 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase N6_N4_Mtase PF01555.13 EGG42033.1 - 2.5e-36 125.3 4.5 3e-36 125.0 3.1 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 EGG42033.1 - 4.8e-09 36.2 0.0 0.00093 19.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.13 EGG42033.1 - 5.5e-06 26.0 0.0 0.049 13.2 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 DEAD PF00270.24 EGG42034.1 - 2e-31 108.7 0.0 5e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG42034.1 - 2.7e-15 55.9 1.1 7.1e-11 41.8 0.1 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF1998 PF09369.5 EGG42034.1 - 1.1e-11 45.1 0.1 2.8e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) SNF2_N PF00176.18 EGG42034.1 - 0.0021 16.9 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain adh_short PF00106.20 EGG42035.1 - 8.2e-28 97.4 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG42035.1 - 3.1e-22 79.5 0.0 4.1e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG42035.1 - 9.2e-10 38.4 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGG42035.1 - 9.9e-07 28.1 0.1 1.1e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EGG42035.1 - 0.024 13.8 0.2 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family DUF1951 PF09188.5 EGG42035.1 - 0.052 13.4 1.4 0.28 11.1 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1951) Topoisom_I_N PF02919.10 EGG42036.1 - 6.6e-70 234.7 6.6 6.6e-70 234.7 4.6 2.8 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EGG42036.1 - 1.6e-65 220.4 11.6 1.6e-65 220.4 8.0 2.3 1 1 1 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EGG42036.1 - 3e-24 84.4 1.1 3e-24 84.4 0.8 3.9 4 0 0 4 4 4 1 C-terminal topoisomerase domain PRA-CH PF01502.13 EGG42036.1 - 0.11 12.1 0.4 0.31 10.7 0.3 1.7 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase DUF3172 PF11371.3 EGG42037.1 - 0.011 15.2 0.1 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3172) T4_Gp59_N PF08993.5 EGG42037.1 - 0.27 11.2 2.6 2.8 8.0 0.2 2.4 1 1 1 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase DUF849 PF05853.7 EGG42037.1 - 0.33 9.7 8.2 0.37 9.6 5.7 1.2 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Intg_mem_TP0381 PF09529.5 EGG42041.1 - 0.061 12.5 15.1 0.068 12.4 10.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF2626 PF11117.3 EGG42041.1 - 3.3 8.2 8.3 8.7 6.8 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2626) GPI2 PF06432.6 EGG42041.1 - 8.1 5.7 11.1 12 5.1 7.7 1.5 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase HTH_24 PF13412.1 EGG42042.1 - 2.9e-11 42.5 0.1 8.4e-07 28.2 0.0 3.2 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 EGG42042.1 - 9.8e-08 31.5 0.2 0.0056 16.3 0.0 2.9 2 1 1 3 3 3 2 Bacterial regulatory protein, arsR family HTH_34 PF13601.1 EGG42042.1 - 1.4e-06 28.2 0.0 0.001 19.0 0.0 2.1 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR PF01047.17 EGG42042.1 - 1.5e-06 27.8 0.0 4.2e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.2 EGG42042.1 - 0.0006 19.4 0.0 0.0054 16.3 0.0 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.14 EGG42042.1 - 0.0029 17.2 0.0 0.93 9.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 EGG42042.1 - 0.0037 17.0 0.1 2.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn-helix HTH_20 PF12840.2 EGG42042.1 - 0.0053 16.5 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.5 EGG42042.1 - 0.012 15.2 0.0 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.1 EGG42042.1 - 0.084 12.6 0.1 5.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TFIIE_alpha PF02002.12 EGG42042.1 - 0.09 12.2 0.1 0.58 9.6 0.0 2.1 1 1 1 2 2 2 0 TFIIE alpha subunit RPA_C PF08784.6 EGG42042.1 - 0.097 13.0 0.1 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Replication protein A C terminal Parecho_VpG PF06344.6 EGG42043.1 - 0.13 12.2 0.3 0.31 11.0 0.2 1.7 1 0 0 1 1 1 0 Parechovirus Genome-linked protein GSDH PF07995.6 EGG42044.1 - 2.2e-98 329.3 0.1 2.8e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Proteasome_A_N PF10584.4 EGG42044.1 - 0.003 16.8 1.1 0.14 11.4 0.1 2.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Tachylectin PF14517.1 EGG42044.1 - 0.0094 15.2 0.2 0.5 9.6 0.0 2.6 3 0 0 3 3 3 1 Tachylectin SGL PF08450.7 EGG42044.1 - 0.072 12.4 0.0 17 4.6 0.0 2.9 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region HATPase_c PF02518.21 EGG42045.1 - 6.5e-27 93.4 0.1 1.4e-26 92.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.19 EGG42045.1 - 1.6e-13 50.4 0.0 2.5e-11 43.3 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EGG42045.1 - 1.8e-12 47.5 0.0 5e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 EGG42045.1 - 4.7e-09 36.1 0.1 9.8e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EGG42045.1 - 7.4e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EGG42045.1 - 0.0002 21.3 0.0 0.0082 16.0 0.0 2.6 2 0 0 2 2 2 1 PAS domain HATPase_c_5 PF14501.1 EGG42045.1 - 0.00023 20.7 0.0 0.00065 19.3 0.0 1.8 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.1 EGG42045.1 - 0.00025 20.7 0.0 0.001 18.8 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 EGG42045.1 - 0.0026 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 EGG42045.1 - 0.0077 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2431 PF10354.4 EGG42045.1 - 0.021 14.7 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2431) Rho_GDI PF02115.12 EGG42045.1 - 0.067 12.6 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Cupredoxin_1 PF13473.1 EGG42046.1 - 2e-05 24.4 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Arch_flagellin PF01917.11 EGG42046.1 - 0.31 10.6 5.2 1.4 8.4 3.6 2.1 1 1 0 1 1 1 0 Archaebacterial flagellin z-alpha PF02295.12 EGG42048.1 - 0.0081 15.9 2.1 0.06 13.1 0.1 3.0 3 0 0 3 3 3 1 Adenosine deaminase z-alpha domain TBPIP PF07106.8 EGG42048.1 - 0.01 15.3 1.1 0.01 15.3 0.8 2.6 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IFT57 PF10498.4 EGG42048.1 - 0.019 13.7 3.5 0.17 10.5 0.7 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 EGG42048.1 - 0.036 13.2 0.2 0.036 13.2 0.2 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EGG42048.1 - 0.047 13.4 3.2 1.9 8.2 0.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3763 PF12592.3 EGG42048.1 - 0.051 13.2 0.6 1.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) FlxA PF14282.1 EGG42048.1 - 0.12 12.3 6.7 1.8 8.5 0.1 3.3 2 2 1 3 3 3 0 FlxA-like protein Erp_C PF06780.6 EGG42048.1 - 0.2 11.5 5.0 2.5 7.9 0.3 2.4 2 0 0 2 2 2 0 Erp protein C-terminus Prefoldin_2 PF01920.15 EGG42048.1 - 0.39 10.5 5.7 2.9 7.7 0.0 3.5 3 1 1 4 4 4 0 Prefoldin subunit DUF1043 PF06295.7 EGG42048.1 - 2.1 8.0 6.0 3.1 7.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) FliD_C PF07195.7 EGG42050.1 - 0.013 14.7 0.8 0.019 14.2 0.3 1.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus VASP_tetra PF08776.6 EGG42050.1 - 0.042 13.1 0.3 0.089 12.1 0.2 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain Syntaxin-6_N PF09177.6 EGG42050.1 - 0.13 12.6 2.1 0.28 11.5 1.5 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Guanylate_cyc PF00211.15 EGG42052.1 - 1.4e-12 47.3 0.0 3.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2582 PF10771.4 EGG42052.1 - 0.007 16.1 0.1 20 5.1 0.0 4.7 4 0 0 4 4 4 1 Protein of unknown function (DUF2582) HATPase_c_4 PF13749.1 EGG42052.1 - 0.02 14.6 0.0 11 5.9 0.0 4.7 5 1 0 5 5 5 0 ATP-dependent DNA helicase recG C-terminal RNA_helicase PF00910.17 EGG42053.1 - 4.8e-05 23.4 0.0 0.00015 21.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 EGG42053.1 - 0.00031 20.4 0.6 0.00098 18.8 0.1 1.9 1 1 0 1 1 1 1 Archaeal ATPase TrwB_AAD_bind PF10412.4 EGG42053.1 - 0.0049 15.5 0.0 0.012 14.2 0.0 1.6 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EGG42053.1 - 0.0082 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Pox_A32 PF04665.7 EGG42053.1 - 0.018 14.3 0.0 0.018 14.3 0.0 2.5 2 1 1 3 3 3 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EGG42053.1 - 0.032 13.7 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EGG42053.1 - 0.16 11.8 3.5 0.24 11.2 0.1 2.8 2 1 1 3 3 3 0 AAA domain UDG PF03167.14 EGG42056.1 - 0.01 15.3 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily CD4-extracel PF09191.5 EGG42056.1 - 0.1 12.6 0.1 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 CD4, extracellular CHAT PF12770.2 EGG42058.1 - 2.2e-25 89.3 0.0 2.9e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.13 EGG42058.1 - 0.0001 21.4 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 DUF3153 PF11353.3 EGG42058.1 - 0.029 13.8 0.6 3.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Lactamase_B PF00753.22 EGG42059.1 - 8.6e-05 22.2 0.0 0.06 12.9 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGG42059.1 - 0.00013 21.5 0.0 0.0007 19.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DZR PF12773.2 EGG42060.1 - 0.0013 18.4 0.3 0.0013 18.4 0.2 1.6 2 0 0 2 2 2 1 Double zinc ribbon Cupredoxin_1 PF13473.1 EGG42060.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain zf-ribbon_3 PF13248.1 EGG42060.1 - 0.008 15.3 4.0 0.008 15.3 2.8 1.9 2 0 0 2 2 2 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGG42060.1 - 0.062 12.9 1.6 0.11 12.1 1.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 EGG42060.1 - 0.12 12.1 3.5 0.35 10.5 2.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF2116 PF09889.4 EGG42060.1 - 0.15 11.9 1.0 0.3 10.9 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Auto_anti-p27 PF06677.7 EGG42060.1 - 0.16 11.7 3.3 0.33 10.7 2.3 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prok-RING_1 PF14446.1 EGG42060.1 - 0.2 11.4 1.3 0.41 10.4 0.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-dskA_traR PF01258.12 EGG42060.1 - 0.24 11.1 1.5 0.83 9.4 1.0 1.9 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_2 PF13240.1 EGG42060.1 - 1.6 8.3 9.4 0.087 12.3 2.7 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_C14 PF00656.17 EGG42061.1 - 2.2e-19 70.1 0.1 4.5e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Caspase domain TPR_1 PF00515.23 EGG42061.1 - 4.9e-16 57.5 0.2 3.5e-05 23.2 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG42061.1 - 7.8e-16 56.6 0.1 0.00072 19.2 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGG42061.1 - 1.9e-13 49.8 0.1 1.7e-06 27.5 0.0 2.8 1 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 EGG42061.1 - 9.7e-08 32.4 0.0 3e-06 27.7 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42061.1 - 1.4e-06 27.6 2.3 0.28 11.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42061.1 - 1.6e-06 28.3 0.0 0.00061 20.0 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42061.1 - 1.7e-06 28.1 0.0 0.06 14.0 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG42061.1 - 7.7e-05 22.8 0.0 1.6 9.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42061.1 - 9.3e-05 22.3 1.2 5.6 7.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG42061.1 - 0.00017 21.6 0.1 0.0015 18.6 0.1 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGG42061.1 - 0.00093 19.0 0.0 0.1 12.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGG42061.1 - 0.0068 16.2 0.0 0.029 14.1 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Peptidase_C13 PF01650.13 EGG42061.1 - 0.026 13.8 0.1 0.11 11.8 0.0 2.0 2 1 1 3 3 3 0 Peptidase C13 family Fis1_TPR_C PF14853.1 EGG42061.1 - 0.056 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Raptor_N PF14538.1 EGG42061.1 - 0.13 12.1 3.2 0.6 9.9 0.1 3.1 2 2 0 2 2 2 0 Raptor N-terminal CASPase like domain Guanylate_cyc PF00211.15 EGG42063.1 - 7.2e-15 54.8 0.0 9.2e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MotA_activ PF09114.5 EGG42064.1 - 1.2e-06 28.2 0.1 3.8e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Transcription factor MotA, activation domain DUF4423 PF14394.1 EGG42064.1 - 1.2e-05 24.8 0.1 6.9e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_20 PF12840.2 EGG42064.1 - 0.00024 20.8 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 EGG42064.1 - 0.00037 19.8 1.2 0.00074 18.8 0.8 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EGG42064.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 MarR family PCI PF01399.22 EGG42064.1 - 0.0025 18.1 0.7 0.027 14.7 0.0 2.4 2 1 0 2 2 2 1 PCI domain HTH_27 PF13463.1 EGG42064.1 - 0.0029 17.9 0.1 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.1 EGG42064.1 - 0.0055 16.6 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_45 PF14947.1 EGG42064.1 - 0.011 15.5 2.0 0.015 15.1 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix HTH_5 PF01022.15 EGG42064.1 - 0.011 15.4 0.2 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR PF01047.17 EGG42064.1 - 0.011 15.4 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.5 EGG42064.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.14 EGG42064.1 - 0.016 14.9 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 EGG42064.1 - 0.019 14.8 0.1 0.046 13.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_Crp_2 PF13545.1 EGG42064.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Nitroreductase PF00881.19 EGG42065.1 - 3.5e-30 105.0 0.0 4.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF2704 PF10866.3 EGG42065.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Peptidase_C14 PF00656.17 EGG42066.1 - 2.8e-21 76.3 0.4 6.4e-21 75.1 0.3 1.6 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.13 EGG42066.1 - 0.00017 20.9 0.1 0.00048 19.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase C13 family Plasmid_parti PF01672.11 EGG42066.1 - 0.31 11.5 2.4 0.56 10.6 0.4 2.5 3 0 0 3 3 3 0 Putative plasmid partition protein CHAT PF12770.2 EGG42067.1 - 8.4e-10 38.2 0.0 3.4e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 CHAT domain Peptidase_C14 PF00656.17 EGG42067.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Caspase domain YuiB PF14068.1 EGG42068.1 - 0.05 13.9 0.1 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative membrane protein DUF11 PF01345.13 EGG42069.1 - 0.0012 18.8 0.4 0.0025 17.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.6 EGG42069.1 - 0.0097 15.9 3.1 0.025 14.6 2.2 1.7 1 0 0 1 1 1 1 CARDB Allexi_40kDa PF05549.6 EGG42069.1 - 0.08 12.2 2.1 0.16 11.2 1.4 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein HJURP_C PF12347.3 EGG42069.1 - 0.49 10.0 5.2 0.083 12.4 0.5 2.0 1 1 1 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF464 PF04327.7 EGG42069.1 - 8.7 6.6 7.7 6.6 7.0 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF464) DUF3169 PF11368.3 EGG42070.1 - 0.006 15.8 1.2 0.009 15.2 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF808 PF05661.7 EGG42070.1 - 0.0097 14.7 0.0 0.015 14.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF808) Peptidase_M48 PF01435.13 EGG42071.1 - 0.073 12.6 0.0 7.4 6.0 0.4 2.5 2 0 0 2 2 2 0 Peptidase family M48 tRNA-synt_2c PF01411.14 EGG42072.1 - 5.3e-82 275.8 0.0 5.3e-82 275.8 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGG42072.1 - 3.4e-15 55.6 0.8 1.1e-14 54.0 0.6 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGG42072.1 - 2.2e-06 27.2 3.7 4.9e-06 26.1 2.5 1.6 1 0 0 1 1 1 1 DHHA1 domain tRNA-synt_1 PF00133.17 EGG42073.1 - 2.1e-57 194.4 1.6 1.2e-56 192.0 1.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGG42073.1 - 1.1e-26 93.4 0.5 7.1e-13 47.9 0.1 3.4 2 1 1 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGG42073.1 - 2.8e-21 75.8 0.7 6e-21 74.7 0.5 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGG42073.1 - 8e-11 41.6 3.2 5.3e-06 25.7 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EGG42073.1 - 2.2e-07 30.3 0.2 1.6e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EGG42073.1 - 0.014 14.2 0.1 0.11 11.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) Ubie_methyltran PF01209.13 EGG42074.1 - 5.8e-20 71.3 0.0 6.4e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGG42074.1 - 2.6e-18 66.0 0.0 2.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG42074.1 - 2.6e-15 56.9 0.0 3.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG42074.1 - 5.7e-15 55.5 0.0 9.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG42074.1 - 2.6e-13 50.2 0.0 5.4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG42074.1 - 4.4e-13 49.5 0.0 7.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG42074.1 - 2.5e-11 43.5 0.0 3.7e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG42074.1 - 3.5e-09 36.2 0.0 8.1e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGG42074.1 - 3.6e-09 36.1 0.0 5.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGG42074.1 - 1.1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGG42074.1 - 3.8e-05 23.1 0.0 5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 EGG42074.1 - 0.00019 20.2 0.0 0.00023 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 EGG42074.1 - 0.00024 20.3 0.0 0.00034 19.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.15 EGG42074.1 - 0.0022 17.0 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 EGG42074.1 - 0.0027 16.8 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EGG42074.1 - 0.0069 17.1 0.0 0.011 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGG42074.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GidB PF02527.10 EGG42074.1 - 0.054 12.6 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G ADH_zinc_N PF00107.21 EGG42074.1 - 0.13 11.8 0.0 0.85 9.1 0.0 2.4 3 1 0 3 3 3 0 Zinc-binding dehydrogenase Methyltransf_32 PF13679.1 EGG42074.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EGG42074.1 - 0.13 11.4 0.0 0.69 9.0 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase zf-dskA_traR PF01258.12 EGG42075.1 - 0.006 16.2 3.2 0.087 12.5 0.3 2.5 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger zf-ribbon_3 PF13248.1 EGG42075.1 - 0.0073 15.4 3.3 0.35 10.1 0.2 2.8 2 1 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 EGG42075.1 - 0.0082 15.9 7.9 0.12 12.1 5.5 2.1 1 1 0 1 1 1 1 Double zinc ribbon zf-DHHC PF01529.15 EGG42075.1 - 0.031 13.6 3.0 0.036 13.4 2.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1610 PF07754.6 EGG42075.1 - 0.39 10.8 4.6 2.1 8.5 3.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) RNA_POL_M_15KD PF02150.11 EGG42075.1 - 0.41 10.3 7.8 0.22 11.2 2.4 2.5 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF2039 PF10217.4 EGG42075.1 - 0.45 10.5 5.7 0.93 9.5 3.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF983 PF06170.7 EGG42075.1 - 1.1 9.3 3.6 2.2 8.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-NADH-PPase PF09297.6 EGG42075.1 - 1.6 8.3 6.3 1.6 8.2 0.1 2.9 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Tnp_zf-ribbon_2 PF13842.1 EGG42075.1 - 2 8.8 8.6 3.7 8.0 2.1 2.9 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-CHY PF05495.7 EGG42075.1 - 2.2 8.4 6.7 6.1 7.0 4.6 1.8 1 1 0 1 1 1 0 CHY zinc finger HypA PF01155.14 EGG42075.1 - 2.4 7.8 7.3 0.51 10.0 2.4 1.7 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EGG42075.1 - 2.5 7.7 10.0 1.1 8.8 0.5 2.9 3 1 0 3 3 3 0 zinc-ribbon domain Stc1 PF12898.2 EGG42075.1 - 4.3 7.4 7.6 38 4.4 5.3 2.1 1 1 0 1 1 1 0 Stc1 domain ADK_lid PF05191.9 EGG42075.1 - 5.3 6.7 7.9 5.4 6.7 0.1 3.2 4 0 0 4 4 4 0 Adenylate kinase, active site lid OrfB_Zn_ribbon PF07282.6 EGG42075.1 - 5.9 6.6 6.6 2.9 7.6 0.7 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Nitroreductase PF00881.19 EGG42076.1 - 3.4e-36 124.5 0.1 5.3e-36 123.9 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.1 EGG42076.1 - 0.0034 16.5 0.0 0.0097 15.1 0.0 1.8 2 0 0 2 2 2 1 Putative TM nitroreductase Trp_halogenase PF04820.9 EGG42077.1 - 3.4e-06 25.9 0.0 1.3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_2 PF03446.10 EGG42077.1 - 0.00014 21.7 0.0 0.00037 20.3 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EGG42077.1 - 0.0007 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EGG42077.1 - 0.0079 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EGG42077.1 - 0.02 14.3 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EGG42077.1 - 0.037 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGG42077.1 - 0.046 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1687 PF07955.6 EGG42077.1 - 0.082 12.8 0.1 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) DAO PF01266.19 EGG42077.1 - 0.09 11.6 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase CxxCxxCC PF03692.10 EGG42078.1 - 7.9e-09 35.8 1.4 5e-08 33.3 1.0 2.1 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Ribosomal_S7 PF00177.16 EGG42080.1 - 5.3e-38 129.9 0.8 7.5e-38 129.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.20 EGG42081.1 - 2e-38 130.5 0.3 2.3e-38 130.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KH_2 PF07650.12 EGG42082.1 - 3e-19 68.3 2.8 6.1e-13 48.1 0.1 2.1 1 1 1 2 2 2 2 KH domain KH_4 PF13083.1 EGG42082.1 - 3.8e-11 42.4 0.5 1.5e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 EGG42082.1 - 8e-07 28.7 2.8 3.3e-06 26.7 0.2 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.24 EGG42082.1 - 2.2e-05 24.0 1.8 0.011 15.3 0.1 2.5 2 0 0 2 2 2 2 KH domain DUF3979 PF13141.1 EGG42082.1 - 0.048 13.5 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) DUF310 PF03750.8 EGG42082.1 - 0.057 13.5 0.1 0.083 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF310) Ribosomal_L7Ae PF01248.21 EGG42083.1 - 1.2e-11 43.9 0.6 1.5e-11 43.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1694 PF07997.6 EGG42083.1 - 0.017 15.0 1.2 0.029 14.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) TPR_11 PF13414.1 EGG42084.1 - 7.3e-20 70.3 0.2 3.3e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGG42084.1 - 1.9e-19 68.3 0.3 9e-07 28.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG42084.1 - 1.3e-16 59.0 0.0 9.5e-05 22.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42084.1 - 1.4e-12 46.7 1.1 0.0019 18.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGG42084.1 - 2e-12 47.4 0.0 5e-06 27.0 0.0 2.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42084.1 - 2e-10 39.6 5.9 0.00051 19.6 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG42084.1 - 1.4e-09 37.7 0.0 2.8e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG42084.1 - 3.5e-08 32.6 0.0 0.0051 16.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42084.1 - 6.9e-06 26.3 0.0 0.07 13.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42084.1 - 2.5e-05 24.4 0.0 0.96 10.2 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG42084.1 - 6.4e-05 22.7 0.0 0.36 10.7 0.0 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 EGG42084.1 - 0.0029 16.4 0.0 0.11 11.2 0.0 2.2 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EGG42084.1 - 0.021 15.2 0.2 2.1 9.0 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGG42084.1 - 0.11 12.4 0.0 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat A2M_N PF01835.14 EGG42085.1 - 0.014 15.6 0.0 0.77 10.0 0.0 2.6 2 0 0 2 2 2 0 MG2 domain DUF1425 PF07233.7 EGG42085.1 - 0.039 13.4 1.2 0.53 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1425) LSM PF01423.17 EGG42086.1 - 2.6e-17 62.1 2.1 3.2e-17 61.8 1.5 1.1 1 0 0 1 1 1 1 LSM domain RNA_pol_Rpb1_5 PF04998.12 EGG42087.1 - 3.2e-85 285.7 1.9 6.5e-85 284.7 1.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EGG42087.1 - 2.9e-83 279.9 0.6 1.7e-81 274.1 0.1 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EGG42087.1 - 4.1e-70 235.0 0.0 8.7e-70 233.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGG42087.1 - 4.1e-35 120.8 0.0 1.2e-34 119.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGG42087.1 - 3.9e-24 84.4 0.2 6.8e-23 80.4 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Peptidase_C34 PF05413.6 EGG42087.1 - 0.064 13.3 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase TniQ PF06527.6 EGG42087.1 - 0.071 13.3 0.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 TniQ UPF0547 PF10571.4 EGG42087.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 RNA_pol_Rpb2_6 PF00562.23 EGG42088.1 - 2.9e-121 404.8 0.0 4.6e-121 404.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGG42088.1 - 3e-56 189.5 0.0 4.4e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EGG42088.1 - 1.1e-29 102.4 0.0 2.4e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EGG42088.1 - 7.9e-27 92.8 0.1 1.9e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EGG42088.1 - 1.2e-23 83.5 0.0 2.8e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EGG42088.1 - 1e-13 50.8 0.1 3.2e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EGG42088.1 - 5e-12 45.6 0.5 1.1e-11 44.5 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 EGG42088.1 - 0.054 13.3 0.2 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37e PF01907.14 EGG42088.1 - 0.19 11.5 0.7 0.47 10.2 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e OrfB_Zn_ribbon PF07282.6 EGG42088.1 - 0.31 10.7 1.6 0.75 9.4 0.6 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RNA_pol_Rpb5_C PF01191.14 EGG42089.1 - 5.8e-29 99.4 0.1 6.8e-29 99.2 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain A2M_N PF01835.14 EGG42090.1 - 4.8e-05 23.5 0.0 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 MG2 domain DUF4493 PF14900.1 EGG42090.1 - 0.031 13.9 3.8 0.15 11.6 0.0 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4493) A2M_N PF01835.14 EGG42091.1 - 1.7e-05 25.0 0.6 0.021 15.0 0.1 2.5 2 1 0 2 2 2 2 MG2 domain P_proprotein PF01483.15 EGG42091.1 - 0.00046 19.9 0.1 0.012 15.3 0.0 2.7 2 1 1 3 3 3 1 Proprotein convertase P-domain PsbH PF00737.15 EGG42091.1 - 0.059 12.9 0.5 0.16 11.5 0.4 1.7 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein FixH PF05751.6 EGG42091.1 - 0.069 12.9 3.6 1.1 9.0 0.0 3.0 2 1 1 3 3 3 0 FixH Cna_B PF05738.8 EGG42091.1 - 0.2 11.4 1.3 0.52 10.1 0.2 2.2 2 1 1 3 3 3 0 Cna protein B-type domain A2M_N PF01835.14 EGG42092.1 - 4.3e-05 23.6 0.1 7.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 MG2 domain Big_2 PF02368.13 EGG42092.1 - 0.55 10.1 5.1 0.25 11.2 1.0 2.4 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 2) A2M_N PF01835.14 EGG42093.1 - 0.022 14.9 0.0 0.059 13.6 0.0 1.7 1 1 0 1 1 1 0 MG2 domain Big_3_4 PF13754.1 EGG42093.1 - 0.075 13.3 2.3 1.1 9.5 0.1 3.4 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF4493 PF14900.1 EGG42093.1 - 0.094 12.3 3.5 0.19 11.3 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4493) Aminotran_5 PF00266.14 EGG42094.1 - 2.2e-85 286.6 0.0 2.5e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGG42094.1 - 6.5e-07 28.6 0.0 1.9e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG42094.1 - 7.4e-07 28.6 0.0 1.5e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGG42094.1 - 3.1e-05 23.1 0.0 8.3e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGG42094.1 - 0.0032 15.7 0.0 0.0048 15.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 EGG42094.1 - 0.038 12.4 0.0 0.08 11.3 0.0 1.5 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain QueC PF06508.8 EGG42095.1 - 1.6e-09 37.3 0.4 4.9e-08 32.5 0.1 2.6 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 EGG42095.1 - 1.4e-08 33.9 0.0 2.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 EGG42095.1 - 2.2e-08 33.0 0.3 9.4e-07 27.7 0.1 2.2 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.15 EGG42095.1 - 2.6e-08 33.5 0.2 3e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EGG42095.1 - 3.9e-07 29.8 0.0 5.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EGG42095.1 - 0.00012 21.6 0.1 0.00027 20.4 0.1 1.6 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 EGG42095.1 - 0.051 12.6 0.9 0.065 12.2 0.3 1.7 2 1 0 2 2 2 0 Arginosuccinate synthase DUF111 PF01969.12 EGG42096.1 - 9.9e-101 337.2 0.7 1.2e-100 337.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 Ldh_1_N PF00056.18 EGG42097.1 - 4.4e-36 123.8 1.6 4.5e-36 123.7 0.3 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGG42097.1 - 1.2e-29 103.2 0.1 2.1e-29 102.4 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EGG42097.1 - 0.12 11.6 1.1 0.54 9.5 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase AIRC PF00731.15 EGG42098.1 - 5.1e-20 71.2 4.7 8.4e-20 70.5 3.3 1.4 1 0 0 1 1 1 1 AIR carboxylase NAD_kinase PF01513.16 EGG42098.1 - 0.014 14.1 0.1 0.026 13.2 0.1 1.5 1 1 0 1 1 1 0 ATP-NAD kinase Radical_SAM PF04055.16 EGG42099.1 - 4.3e-13 49.7 0.0 9.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.14 EGG42099.1 - 0.039 13.8 0.0 0.16 11.8 0.1 2.0 2 1 0 2 2 2 0 B12 binding domain Phage_integrase PF00589.17 EGG42101.1 - 9.9e-06 25.3 1.1 9.9e-06 25.3 0.7 3.2 3 1 0 3 3 3 1 Phage integrase family CALCOCO1 PF07888.6 EGG42101.1 - 0.051 11.8 9.3 0.0053 15.1 3.5 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 EGG42101.1 - 0.1 12.1 6.4 0.21 11.1 4.4 1.4 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 EGG42101.1 - 1.5 8.6 6.4 1 9.1 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cytochrom_D1 PF02239.11 EGG42102.1 - 0.00056 18.3 1.0 0.068 11.4 0.1 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain Lactonase PF10282.4 EGG42102.1 - 0.003 16.7 0.5 0.13 11.3 0.0 2.8 2 1 2 4 4 4 2 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.1 EGG42102.1 - 0.0075 15.7 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Arylesterase PF01731.15 EGG42102.1 - 0.008 16.1 0.9 0.69 9.9 0.0 3.2 3 0 0 3 3 3 1 Arylesterase DUF637 PF04830.8 EGG42102.1 - 0.016 14.9 0.4 0.033 13.8 0.1 1.6 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) Usp PF00582.21 EGG42103.1 - 9.9e-28 97.0 0.1 1.1e-27 96.8 0.1 1.0 1 0 0 1 1 1 1 Universal stress protein family Urb2 PF10441.4 EGG42103.1 - 0.00043 19.9 0.1 0.00051 19.6 0.1 1.2 1 0 0 1 1 1 1 Urb2/Npa2 family LuxC PF05893.9 EGG42103.1 - 0.012 14.3 0.3 0.014 14.1 0.2 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pro_dh PF01619.13 EGG42103.1 - 0.047 12.6 0.5 0.053 12.4 0.4 1.1 1 0 0 1 1 1 0 Proline dehydrogenase Fcf1 PF04900.7 EGG42103.1 - 0.051 13.6 0.6 0.086 12.9 0.4 1.4 1 0 0 1 1 1 0 Fcf1 Methyltransf_31 PF13847.1 EGG42103.1 - 0.055 13.0 0.6 0.11 12.1 0.3 1.5 1 1 0 1 1 1 0 Methyltransferase domain HIT PF01230.18 EGG42103.1 - 0.16 12.4 0.8 0.47 11.0 0.2 1.8 1 1 1 2 2 2 0 HIT domain DUF4098 PF13345.1 EGG42104.1 - 0.02 14.8 1.2 0.02 14.8 0.8 2.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4098) B9-C2 PF07162.6 EGG42104.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein ABC_tran PF00005.22 EGG42106.1 - 1.5e-31 109.5 0.0 1.8e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGG42106.1 - 2.5e-09 37.5 0.0 0.00089 19.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EGG42106.1 - 0.00037 20.5 0.0 0.00067 19.6 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EGG42106.1 - 0.00049 19.3 0.0 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 EGG42106.1 - 0.001 19.2 0.2 0.0094 16.1 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EGG42106.1 - 0.0027 17.1 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGG42106.1 - 0.0034 18.1 0.2 0.0044 17.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG42106.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGG42106.1 - 0.0084 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG42106.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGG42106.1 - 0.013 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EGG42106.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EGG42106.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EGG42106.1 - 0.024 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EGG42106.1 - 0.025 14.7 0.1 0.11 12.7 0.0 2.0 2 1 1 3 3 2 0 RNA helicase Miro PF08477.8 EGG42106.1 - 0.028 14.9 0.0 0.04 14.3 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein SMC_N PF02463.14 EGG42106.1 - 0.028 13.6 0.2 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGG42106.1 - 0.031 14.6 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGG42106.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EGG42106.1 - 0.059 13.6 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EGG42106.1 - 0.084 11.8 0.0 6.3 5.7 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EGG42106.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EGG42106.1 - 0.13 12.1 0.2 0.26 11.2 0.1 1.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EGG42106.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGG42106.1 - 0.14 11.8 0.1 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NMT1_2 PF13379.1 EGG42107.1 - 2.8e-26 92.4 0.0 3.8e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.6 EGG42107.1 - 3.1e-19 69.4 0.0 4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 EGG42107.1 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 EGG42107.1 - 4.6e-05 22.7 0.0 0.00046 19.5 0.0 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_7 PF03480.8 EGG42107.1 - 0.1 11.6 0.0 0.43 9.6 0.0 1.9 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Arginosuc_synth PF00764.14 EGG42108.1 - 2.4e-158 527.2 0.2 2.7e-158 527.0 0.1 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EGG42108.1 - 2e-07 30.7 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGG42108.1 - 5.4e-05 22.5 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EGG42108.1 - 0.032 12.7 0.0 0.066 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase zinc_ribbon_5 PF13719.1 EGG42109.1 - 8.7e-05 22.0 1.2 0.09 12.3 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG42109.1 - 0.00018 21.1 1.1 0.18 11.5 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EGG42109.1 - 0.002 17.5 2.6 0.15 11.5 1.9 2.5 1 1 2 3 3 3 2 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.7 EGG42109.1 - 0.0029 16.8 0.8 0.0049 16.1 0.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RNA_POL_M_15KD PF02150.11 EGG42109.1 - 0.0029 17.2 0.3 0.0046 16.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit zf-HYPF PF07503.7 EGG42109.1 - 0.018 14.4 1.9 0.18 11.2 1.3 2.0 1 1 0 1 1 1 0 HypF finger A2L_zn_ribbon PF08792.5 EGG42109.1 - 0.047 13.1 1.7 1 8.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EGG42109.1 - 0.049 12.8 0.2 7 6.0 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF2387 PF09526.5 EGG42109.1 - 0.06 13.2 0.6 0.075 12.9 0.4 1.1 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 EGG42109.1 - 0.065 13.0 0.7 0.11 12.3 0.5 1.4 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 EGG42109.1 - 0.074 12.7 0.5 0.093 12.4 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_S27e PF01667.12 EGG42109.1 - 0.11 12.0 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 Prok-RING_1 PF14446.1 EGG42109.1 - 0.12 12.1 4.1 0.29 10.8 2.9 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 EGG42109.1 - 0.12 12.4 1.3 0.19 11.7 0.9 1.3 1 0 0 1 1 1 0 zinc-finger Lar_restr_allev PF14354.1 EGG42109.1 - 0.13 12.5 2.6 0.72 10.1 1.8 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-trcl PF13451.1 EGG42109.1 - 0.24 11.0 2.8 0.57 9.8 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain Zn-ribbon_8 PF09723.5 EGG42109.1 - 0.27 11.2 3.0 1.4 8.9 0.1 1.9 1 1 1 2 2 2 0 Zinc ribbon domain DUF4182 PF13790.1 EGG42109.1 - 0.37 10.6 2.6 2.9 7.7 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4182) RimK PF08443.6 EGG42110.1 - 3.4e-45 153.8 0.0 4.7e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 EGG42110.1 - 8.4e-15 54.9 0.0 2.3e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.11 EGG42110.1 - 8.2e-13 47.8 0.0 1.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG42110.1 - 1.6e-09 36.9 0.0 2.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGG42110.1 - 3e-08 33.6 0.1 1.5e-07 31.4 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EGG42110.1 - 1.9e-06 27.3 0.0 1.6e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EGG42110.1 - 8.3e-06 24.7 0.0 0.0045 15.8 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp GARS_A PF01071.14 EGG42110.1 - 0.00021 20.9 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 EGG42110.1 - 0.00029 20.2 0.0 0.0013 18.0 0.0 2.0 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EGG42110.1 - 0.00053 19.4 0.0 0.38 10.1 0.0 2.8 2 1 1 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 EGG42110.1 - 0.03 13.5 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.5 EGG42110.1 - 0.055 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Semialdhyde_dh PF01118.19 EGG42111.1 - 2.2e-35 121.5 0.0 3.6e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 EGG42111.1 - 3.9e-19 69.2 0.0 6.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.17 EGG42111.1 - 0.00012 22.5 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EGG42111.1 - 0.00018 21.4 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EGG42111.1 - 0.00053 19.0 0.0 0.0006 18.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EGG42111.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 EGG42111.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NUDIX PF00293.23 EGG42112.1 - 9.8e-13 47.9 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MTHFR PF02219.12 EGG42113.1 - 1.6e-08 33.9 0.0 0.00035 19.7 0.0 2.1 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase HpaB PF03241.8 EGG42113.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Pterin_bind PF00809.17 EGG42114.1 - 6.6e-22 77.9 0.0 1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme Met_synt_B12 PF02965.12 EGG42114.1 - 3.1e-20 72.2 0.0 6.4e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding PF02310.14 EGG42114.1 - 1.5e-18 66.8 0.0 4.6e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 B12 binding domain B12-binding_2 PF02607.12 EGG42114.1 - 3.8e-14 52.4 0.0 1.3e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 B12 binding domain CdhD PF03599.11 EGG42114.1 - 0.00014 20.4 0.0 0.00026 19.5 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit S-methyl_trans PF02574.11 EGG42115.1 - 7e-67 225.8 0.0 7.9e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase KNTase_C PF07827.6 EGG42115.1 - 0.044 13.5 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 KNTase C-terminal domain 2-Hacid_dh_C PF02826.14 EGG42116.1 - 1.7e-63 212.9 0.5 3e-63 212.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGG42116.1 - 1e-28 99.4 0.2 1.1e-28 99.2 0.2 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGG42116.1 - 0.0008 19.2 0.6 0.0028 17.5 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3436 PF11918.3 EGG42116.1 - 0.019 15.1 0.0 0.084 13.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3436) ThiC PF01964.13 EGG42116.1 - 0.051 12.0 1.9 0.11 11.0 0.8 1.7 2 0 0 2 2 2 0 ThiC family Cu-oxidase_3 PF07732.10 EGG42117.1 - 7.8e-10 38.5 2.3 1.3e-08 34.5 0.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG42117.1 - 0.0038 16.7 2.1 0.26 10.8 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Lyase_1 PF00206.15 EGG42118.1 - 1e-87 294.2 1.6 1.3e-87 293.9 1.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGG42118.1 - 1.9e-12 47.0 0.0 5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Radical_SAM PF04055.16 EGG42119.1 - 9.7e-20 71.3 0.1 1.4e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 EGG42119.1 - 3.4e-15 55.6 1.3 4.8e-15 55.1 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 EGG42119.1 - 0.01 15.6 0.4 0.035 13.9 0.1 2.1 2 0 0 2 2 2 0 TRAM domain Tubulin PF00091.20 EGG42120.1 - 1.1e-14 54.7 1.2 2.3e-13 50.4 0.1 2.4 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Redoxin PF08534.5 EGG42121.1 - 6.7e-08 32.1 0.1 3.6e-05 23.3 0.1 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EGG42121.1 - 2.2e-07 30.6 0.3 2.6e-06 27.1 0.2 2.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EGG42121.1 - 5.8e-05 23.2 0.2 0.00074 19.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG42121.1 - 0.00027 20.9 0.1 0.75 9.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_4 PF13462.1 EGG42121.1 - 0.022 14.7 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin Neur_chan_memb PF02932.11 EGG42122.1 - 1.4e-06 28.4 3.0 2.5e-06 27.5 2.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region 60KD_IMP PF02096.15 EGG42122.1 - 0.76 9.4 4.8 1.3 8.6 3.3 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein SNase PF00565.12 EGG42123.1 - 2e-07 31.2 0.0 3.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pput2613-deam PF14427.1 EGG42123.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Pput_2613-like deaminase Copper-bind PF00127.15 EGG42124.1 - 1e-10 41.6 0.5 1e-10 41.6 0.4 1.6 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EGG42124.1 - 1e-06 28.6 1.4 0.00014 21.6 1.0 2.4 1 1 0 1 1 1 1 Cupredoxin-like domain SoxE PF06525.6 EGG42124.1 - 1.2e-06 27.9 1.4 1.8e-06 27.4 1.0 1.3 1 0 0 1 1 1 1 Sulfocyanin (SoxE) DUF4446 PF14584.1 EGG42124.1 - 0.02 14.7 0.3 0.032 14.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SID-1_RNA_chan PF13965.1 EGG42124.1 - 0.086 11.0 1.2 0.097 10.8 0.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4179 PF13786.1 EGG42124.1 - 0.12 12.6 2.3 0.15 12.3 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) DUF308 PF03729.8 EGG42125.1 - 0.0063 16.4 7.0 0.0081 16.1 4.8 1.1 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) DUF3185 PF11381.3 EGG42125.1 - 0.14 11.9 0.3 0.14 11.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DcuC PF03606.10 EGG42125.1 - 0.32 9.1 3.7 0.35 9.0 2.6 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF1410 PF07198.6 EGG42127.1 - 0.041 14.1 1.4 0.076 13.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) LPAM_1 PF08139.7 EGG42127.1 - 1.6 9.0 3.8 3.6 7.9 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Ribosomal_L15e PF00827.12 EGG42128.1 - 3.6e-44 150.5 3.9 4.4e-44 150.2 2.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Phage_integrase PF00589.17 EGG42129.1 - 2.3e-12 46.9 0.0 4.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.1 EGG42129.1 - 0.012 15.8 0.2 0.039 14.2 0.2 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RHH_1 PF01402.16 EGG42131.1 - 1.9e-05 24.3 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RepB-RCR_reg PF10723.4 EGG42131.1 - 0.023 14.3 0.1 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Replication regulatory protein RepB Lipocalin PF00061.18 EGG42131.1 - 0.1 12.6 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Reprolysin_2 PF13574.1 EGG42133.1 - 0.00059 19.9 2.7 0.00059 19.9 1.9 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EGG42133.1 - 0.00094 18.6 0.1 0.0097 15.3 0.0 2.7 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 EGG42133.1 - 0.0014 19.1 1.8 0.0014 19.1 1.2 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M91 PF14891.1 EGG42133.1 - 0.023 14.7 0.1 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Effector protein EF-hand_8 PF13833.1 EGG42133.1 - 2.5 7.7 5.8 7.3 6.2 0.3 3.2 2 1 1 3 3 3 0 EF-hand domain pair Metallopep PF12044.3 EGG42133.1 - 3.6 5.9 6.0 2.5 6.4 2.4 1.8 2 0 0 2 2 2 0 Putative peptidase family Reprolysin_5 PF13688.1 EGG42133.1 - 9.6 6.0 12.1 0.056 13.3 1.4 2.3 3 1 1 4 4 4 0 Metallo-peptidase family M12 Aldedh PF00171.17 EGG42135.1 - 6.5e-100 334.6 0.2 7.3e-100 334.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_10 PF05971.7 EGG42135.1 - 0.062 12.4 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF890) LuxC PF05893.9 EGG42135.1 - 0.12 11.0 0.0 0.29 9.8 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pro_dh PF01619.13 EGG42136.1 - 1.3e-38 132.7 0.1 2.7e-38 131.7 0.1 1.4 1 1 0 1 1 1 1 Proline dehydrogenase Toprim_3 PF13362.1 EGG42136.1 - 0.055 13.7 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Peptidase_M15_2 PF05951.8 EGG42136.1 - 0.068 12.6 0.2 0.28 10.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) UPF0150 PF03681.10 EGG42136.1 - 0.091 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) NadA PF02445.11 EGG42137.1 - 8.7e-115 382.5 2.7 9.8e-115 382.4 1.9 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein DUF108 PF01958.13 EGG42138.1 - 1.1e-32 112.0 0.5 1.1e-32 112.0 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.11 EGG42138.1 - 4.6e-16 59.2 0.0 9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGG42138.1 - 0.0057 16.9 0.1 0.012 15.9 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGG42138.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EGG42138.1 - 0.052 12.6 0.0 0.51 9.4 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGG42138.1 - 0.094 13.2 0.1 0.5 10.8 0.0 2.1 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF3832 PF12909.2 EGG42138.1 - 0.13 12.3 0.0 0.97 9.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3832) NurA PF09376.5 EGG42141.1 - 2.4e-19 69.7 0.1 3.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NurA domain OpuAC PF04069.7 EGG42141.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.3 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system WW PF00397.21 EGG42141.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 WW domain DUF87 PF01935.12 EGG42142.1 - 4.7e-37 128.0 3.1 4.7e-37 128.0 2.2 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EGG42142.1 - 1.2e-14 54.4 6.0 4.3e-12 46.0 4.2 2.1 1 1 0 1 1 1 1 AAA-like domain HAS-barrel PF09378.5 EGG42142.1 - 0.00033 20.4 0.2 0.00087 19.1 0.1 1.8 1 0 0 1 1 1 1 HAS barrel domain TrwB_AAD_bind PF10412.4 EGG42142.1 - 0.0065 15.1 1.0 0.014 14.0 0.1 1.9 2 1 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EGG42142.1 - 0.023 14.9 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Metallophos_2 PF12850.2 EGG42143.1 - 9.3e-11 41.8 0.4 1.3e-10 41.2 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGG42143.1 - 9e-10 38.2 5.6 1.4e-09 37.6 3.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CENP-C_C PF11699.3 EGG42143.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like DUF211 PF02680.9 EGG42143.1 - 0.42 10.4 4.0 42 4.0 0.7 3.6 3 1 1 4 4 4 0 Uncharacterized ArCR, COG1888 SMC_N PF02463.14 EGG42144.1 - 1.7e-17 63.3 22.0 3.7e-10 39.3 0.8 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGG42144.1 - 5.2e-12 46.5 83.6 6.9e-10 39.5 38.8 4.0 1 1 1 2 2 1 1 AAA domain AAA_21 PF13304.1 EGG42144.1 - 9.6e-11 42.1 25.4 0.01 15.8 17.6 3.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGG42144.1 - 1e-08 34.5 0.1 2.1e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGG42144.1 - 4.4e-08 32.9 0.1 8.7e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EGG42144.1 - 4.6e-08 32.5 53.6 0.0017 17.5 23.5 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_13 PF13166.1 EGG42144.1 - 1.8e-06 26.7 61.9 2.2e-05 23.1 15.1 3.8 1 1 3 4 4 4 3 AAA domain ABC_tran PF00005.22 EGG42144.1 - 0.00053 20.3 24.8 0.011 15.9 0.0 5.1 2 1 1 3 3 2 2 ABC transporter DUF258 PF03193.11 EGG42144.1 - 0.0021 17.2 1.0 0.0063 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DNA_ligase_ZBD PF03119.11 EGG42144.1 - 0.06 13.0 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain MMR_HSR1 PF01926.18 EGG42144.1 - 0.1 12.5 3.3 0.36 10.7 0.0 3.3 3 1 0 3 3 3 0 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.1 EGG42144.1 - 0.28 10.8 1.3 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CxxCxxCC PF03692.10 EGG42148.1 - 2.8e-09 37.3 0.6 5.1e-09 36.4 0.4 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF2054 PF10218.4 EGG42148.1 - 0.11 12.2 2.4 7.9 6.3 1.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) Copper-bind PF00127.15 EGG42149.1 - 3.6e-18 65.5 2.2 1.5e-09 37.9 0.1 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EGG42149.1 - 2.2e-14 53.2 0.0 7e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Cupredoxin-like domain SprT-like PF10263.4 EGG42150.1 - 0.0018 17.9 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.12 EGG42150.1 - 0.0038 17.0 0.0 0.0081 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function DUF45 WLM PF08325.5 EGG42150.1 - 0.049 13.5 0.1 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 WLM domain Peptidase_M76 PF09768.4 EGG42150.1 - 0.057 12.8 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family Cu-oxidase_3 PF07732.10 EGG42151.1 - 6.5e-27 93.6 6.6 1.4e-24 86.0 0.2 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG42151.1 - 2.7e-14 52.8 8.6 0.00012 21.6 0.3 3.7 4 0 0 4 4 4 3 Multicopper oxidase Cupredoxin_1 PF13473.1 EGG42151.1 - 3.2e-09 36.6 0.1 0.00012 21.9 0.0 3.5 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.15 EGG42151.1 - 6e-09 36.0 8.6 4.8e-06 26.7 0.3 4.0 3 2 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family COX2 PF00116.15 EGG42151.1 - 0.029 14.2 1.9 0.16 11.8 0.4 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, periplasmic domain DUF359 PF04019.7 EGG42152.1 - 3.4e-32 110.3 0.0 4.4e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF359) ParA PF10609.4 EGG42153.1 - 5.3e-36 122.3 0.3 1.5e-35 120.8 0.2 1.8 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGG42153.1 - 6.1e-20 71.4 0.1 9.8e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 EGG42153.1 - 1.3e-17 63.5 0.2 1.3e-17 63.5 0.1 2.4 4 0 0 4 4 4 1 Domain of unknown function DUF59 AAA_31 PF13614.1 EGG42153.1 - 1.6e-11 44.3 0.6 6.9e-11 42.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain MipZ PF09140.6 EGG42153.1 - 2e-08 33.6 0.0 3.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EGG42153.1 - 2.5e-07 30.4 0.6 0.003 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.13 EGG42153.1 - 1.5e-06 27.6 0.1 0.001 18.3 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 EGG42153.1 - 1.2e-05 24.5 1.5 2.7e-05 23.3 0.6 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.6 EGG42153.1 - 0.0021 17.1 0.0 0.0051 15.9 0.0 1.6 1 0 0 1 1 1 1 VirC1 protein AAA_25 PF13481.1 EGG42153.1 - 0.017 14.5 0.5 0.042 13.2 0.3 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGG42153.1 - 0.017 13.8 0.4 0.027 13.2 0.3 1.2 1 0 0 1 1 1 0 ArgK protein APS_kinase PF01583.15 EGG42153.1 - 0.069 12.8 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase S1 PF00575.18 EGG42154.1 - 1.8e-14 53.5 0.0 2.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.12 EGG42154.1 - 3.4e-06 27.0 0.0 1.1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1_2 PF13509.1 EGG42154.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 S1 domain BPL_C PF02237.12 EGG42154.1 - 0.023 14.3 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Spt4 PF06093.8 EGG42155.1 - 1.4e-13 50.5 0.5 1.7e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.10 EGG42155.1 - 0.0051 16.2 0.8 0.0065 15.8 0.5 1.2 1 0 0 1 1 1 1 RecR protein Laminin_EGF PF00053.19 EGG42155.1 - 0.041 13.8 0.5 0.056 13.3 0.3 1.2 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) TF_Zn_Ribbon PF08271.7 EGG42155.1 - 0.088 12.1 0.8 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding RPA_interact_C PF14768.1 EGG42155.1 - 0.12 12.7 1.1 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Replication protein A interacting C-terminal zf-C3HC4_3 PF13920.1 EGG42155.1 - 0.27 10.9 3.1 0.4 10.4 2.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prim_Zn_Ribbon PF08273.7 EGG42155.1 - 1.2 9.2 3.9 1.9 8.6 0.2 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase QRPTase_C PF01729.14 EGG42156.1 - 6.3e-56 188.5 1.2 8.4e-56 188.1 0.8 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGG42156.1 - 3.8e-28 97.1 0.0 8.5e-28 96.0 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 EGG42156.1 - 0.0091 15.1 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TPR_11 PF13414.1 EGG42157.1 - 9e-18 63.6 0.2 1.3e-08 34.3 0.0 2.1 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGG42157.1 - 6e-13 47.8 1.3 4.4e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG42157.1 - 5.6e-12 45.4 0.1 6e-07 29.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42157.1 - 7.9e-12 45.3 0.0 7.1e-08 32.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG42157.1 - 1.1e-11 43.7 0.0 0.00033 20.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42157.1 - 1.1e-10 40.4 0.7 0.0013 18.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG42157.1 - 5.5e-10 39.2 0.1 8e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGG42157.1 - 2.9e-07 30.9 0.0 5.4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG42157.1 - 3.2e-05 23.3 0.0 0.015 15.0 0.0 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42157.1 - 6.2e-05 22.8 0.1 0.045 13.9 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG42157.1 - 0.00023 21.3 0.0 0.14 12.6 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42157.1 - 0.00058 20.2 0.0 5.9 7.8 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG42157.1 - 0.00099 18.9 0.6 1.9 8.4 0.0 3.2 1 1 2 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EGG42157.1 - 0.03 14.1 4.3 0.097 12.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4284 PF14112.1 EGG42157.1 - 0.032 14.6 1.2 0.66 10.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4284) ChAPs PF09295.5 EGG42157.1 - 0.039 12.7 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DXP_reductoisom PF02670.11 EGG42157.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase P4Ha_N PF08336.6 EGG42157.1 - 0.077 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Clathrin PF00637.15 EGG42157.1 - 0.1 12.1 1.3 0.16 11.5 0.9 1.4 1 1 0 1 1 1 0 Region in Clathrin and VPS Arginase PF00491.16 EGG42158.1 - 1.2e-60 205.1 0.0 1.4e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family ABC_tran PF00005.22 EGG42159.1 - 3.9e-23 82.2 0.1 1.2e-09 38.5 0.0 4.4 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.14 EGG42159.1 - 3.1e-10 39.6 1.1 0.066 12.4 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGG42159.1 - 6.9e-08 31.9 0.3 0.014 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGG42159.1 - 8.4e-07 28.3 0.4 0.0069 15.5 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGG42159.1 - 1.1e-06 28.7 0.0 0.01 15.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EGG42159.1 - 2.5e-06 27.7 16.7 0.0044 17.0 0.1 4.8 5 0 0 5 5 5 2 AAA domain AAA_14 PF13173.1 EGG42159.1 - 3.4e-06 26.9 0.1 0.18 11.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGG42159.1 - 4.2e-06 26.6 0.2 0.11 12.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 EGG42159.1 - 5.8e-06 25.8 0.0 0.14 11.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_10 PF12846.2 EGG42159.1 - 3.7e-05 23.3 0.1 0.12 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EGG42159.1 - 4.4e-05 23.6 2.2 0.38 10.8 0.0 4.1 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 EGG42159.1 - 7.5e-05 23.0 0.1 0.98 9.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EGG42159.1 - 0.00011 22.0 0.6 0.2 11.3 0.0 3.4 3 0 0 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 EGG42159.1 - 0.00014 20.8 0.1 0.28 9.9 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain MMR_HSR1 PF01926.18 EGG42159.1 - 0.00026 20.9 4.2 0.0095 15.8 0.0 3.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EGG42159.1 - 0.0003 20.3 0.0 0.041 13.4 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EGG42159.1 - 0.00039 20.1 0.3 0.045 13.4 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EGG42159.1 - 0.0005 19.7 0.4 1.2 8.7 0.0 2.9 3 0 0 3 3 3 2 Adenylylsulphate kinase AAA_23 PF13476.1 EGG42159.1 - 0.00056 20.2 0.1 0.00056 20.2 0.1 3.8 5 0 0 5 5 3 1 AAA domain AAA_17 PF13207.1 EGG42159.1 - 0.00084 20.1 9.3 0.2 12.5 0.3 4.1 4 1 1 5 5 3 2 AAA domain KaiC PF06745.8 EGG42159.1 - 0.00088 18.4 0.3 1.1 8.3 0.0 3.1 3 0 0 3 3 3 2 KaiC AAA_19 PF13245.1 EGG42159.1 - 0.00098 18.8 0.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain NACHT PF05729.7 EGG42159.1 - 0.0016 18.1 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DnaJ_CXXCXGXG PF00684.14 EGG42159.1 - 0.0024 17.8 0.5 0.0024 17.8 0.4 4.2 4 1 1 5 5 4 1 DnaJ central domain cobW PF02492.14 EGG42159.1 - 0.004 16.6 0.7 0.51 9.7 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGG42159.1 - 0.0052 16.2 0.1 3.4 7.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EGG42159.1 - 0.0062 15.4 0.3 2.2 7.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 EGG42159.1 - 0.008 15.9 0.8 1.4 8.6 0.0 3.6 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.17 EGG42159.1 - 0.011 15.9 0.1 4.5 7.4 0.0 3.2 3 0 0 3 3 2 0 RNA helicase PRK PF00485.13 EGG42159.1 - 0.012 15.1 0.5 0.43 10.0 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 EGG42159.1 - 0.012 14.3 0.0 0.5 9.1 0.0 2.6 2 0 0 2 2 2 0 ArgK protein DUF2075 PF09848.4 EGG42159.1 - 0.023 13.6 0.0 4.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 EGG42159.1 - 0.027 14.9 0.2 6.4 7.2 0.1 2.9 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EGG42159.1 - 0.046 12.8 0.0 2.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 EGG42159.1 - 0.049 13.5 0.1 11 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGG42159.1 - 0.14 11.7 0.0 17 4.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2972 PF11186.3 EGG42159.1 - 0.19 11.6 3.3 0.23 11.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2972) UvrB PF12344.3 EGG42160.1 - 8.4e-23 79.6 4.2 2.6e-22 78.0 2.9 1.9 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.26 EGG42160.1 - 3.6e-15 55.5 0.0 9.4e-15 54.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UVR PF02151.14 EGG42160.1 - 1.8e-10 40.0 4.5 1e-09 37.5 3.1 2.4 1 0 0 1 1 1 1 UvrB/uvrC motif ResIII PF04851.10 EGG42160.1 - 2.2e-08 34.1 0.0 2.2e-08 34.1 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGG42160.1 - 1.8e-07 30.8 0.3 7.6e-05 22.2 0.1 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EGG42160.1 - 0.00012 21.7 0.2 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EGG42160.1 - 0.018 14.6 0.1 0.47 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EGG42160.1 - 0.038 14.1 3.4 1.3 9.1 0.0 3.3 4 1 0 4 4 3 0 AAA domain AAA_33 PF13671.1 EGG42160.1 - 0.11 12.3 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Met_synt_B12 PF02965.12 EGG42160.1 - 0.12 11.5 1.2 0.29 10.3 0.2 2.0 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain ABC_tran PF00005.22 EGG42160.1 - 0.22 11.8 2.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Pyridox_ox_2 PF12900.2 EGG42161.1 - 3.7e-11 43.0 0.0 4.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EGG42161.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cep57_MT_bd PF06657.8 EGG42162.1 - 0.00023 21.0 3.7 0.0003 20.6 2.6 1.1 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 FCH PF00611.18 EGG42162.1 - 0.007 16.5 3.3 0.0091 16.1 1.4 1.7 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain CR6_interact PF10147.4 EGG42162.1 - 0.023 14.0 6.3 0.026 13.8 4.4 1.0 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Glyco_hydro_26 PF02156.10 EGG42162.1 - 0.026 14.0 0.2 0.028 13.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Tho2 PF11262.3 EGG42162.1 - 0.088 11.8 8.1 0.1 11.6 5.6 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Lumazine_bd PF12870.2 EGG42162.1 - 0.16 12.0 5.2 0.19 11.8 3.6 1.2 1 0 0 1 1 1 0 Lumazine-binding domain MRP-L46 PF11788.3 EGG42162.1 - 0.17 12.5 4.5 0.2 12.3 3.1 1.1 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Uds1 PF15456.1 EGG42162.1 - 0.23 11.4 5.6 0.75 9.7 0.9 2.0 1 1 1 2 2 2 0 Up-regulated During Septation APG6 PF04111.7 EGG42162.1 - 0.25 10.3 5.4 0.27 10.2 3.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 EGG42162.1 - 0.29 10.3 2.2 0.3 10.3 1.6 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF262 PF03235.9 EGG42162.1 - 0.43 10.5 3.6 0.44 10.4 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 eIF3_subunit PF08597.5 EGG42162.1 - 0.51 9.8 9.9 0.55 9.7 6.9 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2935 PF11155.3 EGG42162.1 - 1.8 8.7 5.2 2.8 8.0 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Hepatitis_core PF00906.15 EGG42163.1 - 1.1 8.8 5.2 1.6 8.3 3.6 1.2 1 0 0 1 1 1 0 Hepatitis core antigen LOH1CR12 PF10158.4 EGG42164.1 - 0.056 13.2 2.6 0.072 12.8 1.4 1.5 1 1 0 1 1 1 0 Tumour suppressor protein Bac_luciferase PF00296.15 EGG42165.1 - 2.4e-54 184.5 0.0 3.1e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe-ADH PF00465.14 EGG42166.1 - 7.7e-50 169.5 0.0 2.7e-49 167.7 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGG42166.1 - 1.1e-18 67.4 0.0 1.5e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EGG42166.1 - 0.005 15.7 0.0 0.61 8.9 0.0 2.4 2 0 0 2 2 2 2 3-dehydroquinate synthase DUF4147 PF13660.1 EGG42167.1 - 3.6e-71 239.0 0.0 4.7e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 EGG42167.1 - 7e-26 90.4 1.2 1.3e-25 89.6 0.3 1.9 2 0 0 2 2 2 1 MOFRL family Usp PF00582.21 EGG42168.1 - 5.8e-30 104.3 0.0 6.5e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family AAA_13 PF13166.1 EGG42169.1 - 0.023 13.2 3.6 0.026 13.0 2.5 1.1 1 0 0 1 1 1 0 AAA domain Dynamin_M PF01031.15 EGG42169.1 - 0.042 12.6 1.2 0.051 12.3 0.8 1.1 1 0 0 1 1 1 0 Dynamin central region AA_permease_2 PF13520.1 EGG42170.1 - 6.6e-55 186.3 57.6 7.7e-55 186.1 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGG42170.1 - 8.7e-38 129.8 49.7 1.1e-37 129.5 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 EGG42170.1 - 0.032 14.1 1.7 0.032 14.1 1.1 4.4 6 0 0 6 6 6 0 C-terminus of AA_permease E1-E2_ATPase PF00122.15 EGG42171.1 - 5e-49 166.4 1.1 5e-49 166.4 0.8 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EGG42171.1 - 8.9e-41 140.6 0.4 1.4e-40 139.9 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG42171.1 - 4.3e-14 53.1 0.0 9.1e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGG42171.1 - 0.00048 19.7 1.0 0.017 14.7 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1402 PF07182.6 EGG42171.1 - 0.07 11.9 0.0 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1402) CBS PF00571.23 EGG42172.1 - 1.5e-53 178.2 10.1 5.4e-14 51.6 0.0 4.1 4 0 0 4 4 4 4 CBS domain Peptidase_S55 PF05580.7 EGG42172.1 - 0.0015 17.9 0.1 0.0015 17.9 0.1 1.9 2 1 0 2 2 2 1 SpoIVB peptidase S55 PduV-EutP PF10662.4 EGG42172.1 - 0.021 14.2 9.5 2.4 7.6 0.3 4.1 2 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Radical_SAM PF04055.16 EGG42173.1 - 2.7e-10 40.6 1.5 2.8e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EGG42173.1 - 0.037 14.1 1.7 0.039 14.0 0.1 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain zf-CHCC PF10276.4 EGG42173.1 - 3.2 7.6 6.9 1.1 9.1 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger domain AdoMet_Synthase PF01941.14 EGG42174.1 - 1e-70 238.2 0.1 1.2e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) DUF1892 PF08987.5 EGG42174.1 - 0.076 13.0 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1892) AdoMet_Synthase PF01941.14 EGG42175.1 - 3.7e-47 160.7 0.4 4e-47 160.5 0.3 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) 5HT_transporter PF03491.8 EGG42175.1 - 0.07 13.2 0.6 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus PCMT PF01135.14 EGG42176.1 - 4.1e-60 202.9 0.0 5e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGG42176.1 - 5.3e-11 42.3 0.0 8.7e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG42176.1 - 2.9e-09 37.4 0.0 6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGG42176.1 - 1.2e-08 34.3 0.0 1.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EGG42176.1 - 9.9e-06 25.0 0.0 2.4e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGG42176.1 - 1.6e-05 24.0 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGG42176.1 - 2.8e-05 24.1 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EGG42176.1 - 0.0001 21.8 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GidB PF02527.10 EGG42176.1 - 0.00019 20.6 0.1 0.0004 19.5 0.0 1.6 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.7 EGG42176.1 - 0.00043 20.7 0.0 0.00072 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGG42176.1 - 0.0011 18.0 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGG42176.1 - 0.0054 16.4 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG42176.1 - 0.0055 17.0 0.0 0.0094 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGG42176.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EGG42176.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.12 EGG42176.1 - 0.012 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DUF938 PF06080.7 EGG42176.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 EGG42176.1 - 0.027 15.2 0.0 0.047 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EGG42176.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 EGG42176.1 - 0.032 13.2 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 EGG42176.1 - 0.074 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EGG42176.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MgtC PF02308.11 EGG42177.1 - 7.7e-36 122.9 7.7 9.5e-36 122.6 5.4 1.1 1 0 0 1 1 1 1 MgtC family Cpn60_TCP1 PF00118.19 EGG42178.1 - 1.4e-157 525.2 18.9 1.6e-157 525.0 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 EGG42178.1 - 0.031 14.1 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) TF_Zn_Ribbon PF08271.7 EGG42179.1 - 0.0058 15.9 0.7 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EGG42179.1 - 0.0084 15.5 0.4 0.33 10.4 0.1 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain Rtf2 PF04641.7 EGG42179.1 - 0.016 14.3 0.2 0.016 14.3 0.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2HC5 PF06221.8 EGG42179.1 - 0.018 14.8 0.5 0.02 14.6 0.3 1.1 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Zn-ribbon_8 PF09723.5 EGG42179.1 - 0.021 14.7 1.0 0.043 13.7 0.7 1.5 1 1 0 1 1 1 0 Zinc ribbon domain zf-TFIIB PF13453.1 EGG42179.1 - 0.023 13.8 0.8 0.07 12.3 0.0 1.9 1 1 0 2 2 2 0 Transcription factor zinc-finger HypA PF01155.14 EGG42179.1 - 0.04 13.5 0.1 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family RecR PF02132.10 EGG42179.1 - 0.048 13.0 1.4 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 RecR protein DUF2072 PF09845.4 EGG42179.1 - 0.061 13.2 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-RING_3 PF14369.1 EGG42179.1 - 0.064 13.2 0.1 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 zinc-finger UPF0547 PF10571.4 EGG42179.1 - 0.1 12.2 2.3 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DZR PF12773.2 EGG42179.1 - 0.12 12.1 0.9 0.19 11.5 0.6 1.5 1 1 0 1 1 1 0 Double zinc ribbon Rubredoxin PF00301.15 EGG42179.1 - 0.13 12.1 0.4 5.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin zf-C2H2_6 PF13912.1 EGG42179.1 - 0.9 9.5 2.9 1.2 9.0 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger RNA_pol_A_CTD PF03118.10 EGG42180.1 - 0.033 13.5 2.0 0.097 12.0 1.0 2.0 1 1 1 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Usp PF00582.21 EGG42181.1 - 1.7e-15 57.4 0.0 1.8e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Gar1 PF04410.9 EGG42181.1 - 0.063 12.7 1.2 3.3 7.1 0.1 2.0 1 1 1 2 2 2 0 Gar1/Naf1 RNA binding region Usp PF00582.21 EGG42182.1 - 2.2e-05 24.6 0.0 2.7e-05 24.3 0.0 1.2 1 1 0 1 1 1 1 Universal stress protein family Vps51 PF08700.6 EGG42182.1 - 0.067 13.0 0.2 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 Vps51/Vps67 Glycos_trans_3N PF02885.12 EGG42183.1 - 7.7e-10 38.2 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.16 EGG42183.1 - 3e-08 33.3 0.1 1.5e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family, a/b domain Molydop_binding PF01568.16 EGG42183.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain CDC48_N PF02359.13 EGG42183.1 - 0.00017 21.4 0.1 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain PYNP_C PF07831.8 EGG42184.1 - 7.7e-13 47.7 0.2 1.5e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain CAT_RBD PF03123.10 EGG42184.1 - 0.0096 15.5 0.6 0.053 13.2 0.3 2.3 2 0 0 2 2 2 1 CAT RNA binding domain Biotin_lipoyl_2 PF13533.1 EGG42184.1 - 0.023 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EGG42184.1 - 0.055 13.1 0.2 0.72 9.5 0.0 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme DUF2254 PF10011.4 EGG42184.1 - 0.068 11.6 0.1 0.096 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Pribosyltran_N PF13793.1 EGG42185.1 - 5.9e-24 84.0 0.0 1.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EGG42185.1 - 2.5e-10 40.1 0.0 1.2e-09 37.9 0.0 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGG42185.1 - 0.00024 20.3 0.0 0.00053 19.2 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.1 EGG42185.1 - 0.00076 19.2 0.0 0.0031 17.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain PRTase_2 PF15609.1 EGG42185.1 - 0.0029 16.9 0.0 0.0051 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase DUF4419 PF14388.1 EGG42185.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) MFS_1_like PF12832.2 EGG42185.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 MFS_1 like family AAA_33 PF13671.1 EGG42186.1 - 2.6e-14 53.3 0.6 3.6e-13 49.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGG42186.1 - 2e-05 23.9 1.9 4.8e-05 22.6 0.4 1.8 1 1 1 2 2 2 1 Chromatin associated protein KTI12 Pterin_bind PF00809.17 EGG42186.1 - 0.041 13.2 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Pterin binding enzyme Peptidase_M29 PF02073.10 EGG42186.1 - 0.043 12.5 0.1 0.053 12.2 0.1 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) DPBB_1 PF03330.13 EGG42186.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel FlpD PF02662.11 EGG42187.1 - 0.01 15.5 0.5 0.018 14.7 0.2 1.5 1 1 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Syntaxin_2 PF14523.1 EGG42187.1 - 0.019 14.9 1.2 0.02 14.9 0.8 1.1 1 0 0 1 1 1 0 Syntaxin-like protein Syntaxin PF00804.20 EGG42187.1 - 0.095 12.8 1.2 0.1 12.7 0.8 1.2 1 0 0 1 1 1 0 Syntaxin Pox_TAA1 PF03295.9 EGG42187.1 - 0.18 11.5 2.4 0.97 9.1 0.1 2.1 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal DNase-RNase PF02577.9 EGG42188.1 - 1e-11 44.1 0.0 1.1e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease CBS PF00571.23 EGG42189.1 - 1.5e-09 37.4 0.0 4.4e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 CBS domain Zip PF02535.17 EGG42191.1 - 5.6e-10 38.7 3.5 6.4e-10 38.5 2.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Herpes_UL43 PF05072.8 EGG42191.1 - 0.05 12.3 0.4 0.058 12.1 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein DUF204 PF02659.10 EGG42191.1 - 1.3 9.1 7.4 3.6 7.7 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF Response_reg PF00072.19 EGG42192.1 - 0.00014 21.7 0.0 0.00016 21.6 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.19 EGG42193.1 - 7.5e-10 38.8 0.0 8.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.19 EGG42195.1 - 3.1e-24 85.1 0.1 3.6e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.19 EGG42196.1 - 8e-24 83.8 0.4 1e-23 83.5 0.2 1.1 1 0 0 1 1 1 1 Response regulator receiver domain AsnC_trans_reg PF01037.16 EGG42197.1 - 2.2e-08 33.7 0.0 2.6e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 EGG42197.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 GYD domain PRANC PF09372.5 EGG42197.1 - 0.088 12.7 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 PRANC domain Ten1_2 PF15490.1 EGG42197.1 - 0.11 12.0 0.1 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit AsnC_trans_reg PF01037.16 EGG42198.1 - 1.7e-11 43.6 0.1 1.9e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 AsnC family ACT_4 PF13291.1 EGG42198.1 - 0.01 16.1 0.2 4.8 7.5 0.0 2.1 2 0 0 2 2 2 0 ACT domain RimK PF08443.6 EGG42198.1 - 0.02 14.3 0.2 0.02 14.3 0.2 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Lactamase_B_2 PF12706.2 EGG42200.1 - 0.0081 15.7 0.4 1.2 8.6 0.4 2.8 2 1 0 2 2 2 2 Beta-lactamase superfamily domain RMMBL PF07521.7 EGG42200.1 - 0.016 14.9 0.0 0.05 13.4 0.0 1.9 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Response_reg PF00072.19 EGG42201.1 - 6.7e-20 71.1 0.1 8.2e-20 70.8 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Mur_ligase PF01225.20 EGG42201.1 - 0.005 16.8 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, catalytic domain DUF1188 PF06690.6 EGG42201.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Formyl_trans_N PF00551.14 EGG42202.1 - 1.2e-46 158.4 0.0 1.4e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Cupin_2 PF07883.6 EGG42203.1 - 3e-09 36.2 0.0 3.2e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.3 EGG42203.1 - 0.00011 22.0 0.0 0.00012 21.9 0.0 1.0 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.14 EGG42203.1 - 0.00065 19.3 0.0 0.00073 19.2 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Pirin_C PF05726.8 EGG42203.1 - 0.0047 16.9 0.0 0.0059 16.6 0.0 1.0 1 0 0 1 1 1 1 Pirin C-terminal cupin domain 3-HAO PF06052.7 EGG42203.1 - 0.0083 15.5 0.1 0.011 15.1 0.1 1.3 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Ectoine_synth PF06339.7 EGG42203.1 - 0.049 13.5 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Ectoine synthase Auxin_BP PF02041.11 EGG42203.1 - 0.11 11.8 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein ABM PF03992.11 EGG42204.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.6 EGG42204.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1330) THF_DHG_CYH_C PF02882.14 EGG42205.1 - 7.3e-59 197.4 0.8 1.1e-58 196.9 0.6 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGG42205.1 - 3.8e-41 139.7 1.5 3.8e-41 139.7 1.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SIMPL PF04402.9 EGG42205.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF1884 PF08967.5 EGG42205.1 - 0.023 14.7 0.5 0.15 12.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1884) 5-FTHF_cyc-lig PF01812.15 EGG42206.1 - 3e-21 76.0 0.0 3.3e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GARS_A PF01071.14 EGG42207.1 - 1.7e-34 119.1 0.1 2.1e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C PF02843.11 EGG42207.1 - 6.2e-31 106.4 0.0 8.8e-31 105.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain GARS_N PF02844.10 EGG42208.1 - 2.3e-34 117.8 0.0 4.4e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_A PF01071.14 EGG42208.1 - 8e-23 81.0 0.3 1.2e-22 80.4 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.17 EGG42208.1 - 2.7e-06 26.8 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EGG42208.1 - 7.6e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EGG42208.1 - 8.8e-05 22.0 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG42208.1 - 0.0005 18.9 0.0 0.00056 18.7 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EGG42208.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG42208.1 - 0.0017 17.7 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EGG42208.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain tRNA-synt_1 PF00133.17 EGG42209.1 - 1.9e-143 478.6 0.4 2.7e-143 478.1 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGG42209.1 - 2e-31 108.8 1.1 4.9e-31 107.5 0.8 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGG42209.1 - 3.5e-24 85.2 3.1 1.7e-09 36.8 0.1 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EGG42209.1 - 2.7e-05 23.4 0.0 0.0005 19.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EGG42209.1 - 0.00046 18.9 0.4 0.0019 16.9 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (K) Ferritin PF00210.19 EGG42210.1 - 1.5e-18 66.9 0.0 2.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 EGG42210.1 - 0.039 14.2 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Rubrerythrin tRNA_bind PF01588.15 EGG42211.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative tRNA binding domain ATP-grasp_2 PF08442.5 EGG42212.1 - 1.6e-46 158.2 0.8 2.9e-46 157.4 0.6 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EGG42212.1 - 1.7e-15 56.9 1.3 2.3e-15 56.5 0.2 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EGG42212.1 - 6.4e-13 48.4 0.2 2.3e-12 46.6 0.1 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGG42212.1 - 8.9e-06 25.1 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 EGG42212.1 - 0.00041 20.1 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF362 PF04015.7 EGG42212.1 - 0.014 14.8 0.0 0.12 11.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF362) ATP-grasp PF02222.17 EGG42212.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain CoA_binding PF02629.14 EGG42213.1 - 1.8e-21 76.4 1.6 1.8e-21 76.4 1.1 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGG42213.1 - 9.9e-09 34.9 0.2 1.7e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.1 EGG42213.1 - 7.4e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 EGG42213.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.17 EGG42213.1 - 0.00026 21.4 0.1 0.00048 20.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribul_P_3_epim PF00834.14 EGG42213.1 - 0.061 12.4 0.1 0.098 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Response_reg PF00072.19 EGG42216.1 - 4.5e-19 68.5 0.4 5e-19 68.3 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain TK PF00265.13 EGG42216.1 - 0.13 11.8 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Thymidine kinase RHH_1 PF01402.16 EGG42217.1 - 0.07 13.0 0.3 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family YcxB PF14317.1 EGG42218.1 - 0.043 13.0 0.1 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 YcxB-like protein Amidohydro_5 PF13594.1 EGG42219.1 - 1.3e-13 50.5 2.6 4.3e-13 48.8 1.8 1.9 1 0 0 1 1 1 1 Amidohydrolase Kazal_1 PF00050.16 EGG42219.1 - 5e-09 36.0 0.9 1.3e-08 34.6 0.6 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain D-aminoacyl_C PF07908.7 EGG42219.1 - 4.4e-08 32.3 0.0 1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Kazal_2 PF07648.10 EGG42219.1 - 4.9e-08 32.7 1.3 9.5e-08 31.8 0.9 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Amidohydro_1 PF01979.15 EGG42219.1 - 1.8e-05 24.5 0.2 0.027 14.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGG42219.1 - 8.7e-05 22.6 0.1 0.019 15.0 0.0 2.7 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGG42219.1 - 0.0026 17.0 0.5 0.13 11.4 0.2 2.6 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.15 EGG42220.1 - 5.3e-26 92.0 0.5 7.4e-26 91.5 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGG42220.1 - 1.3e-13 50.5 0.4 4.3e-13 48.8 0.3 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGG42220.1 - 6.6e-11 42.7 0.4 3.4e-06 27.3 0.4 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EGG42220.1 - 1.2e-05 24.6 2.5 0.0012 18.1 1.4 2.3 1 1 1 2 2 2 2 Amidohydrolase family DUF1059 PF06348.6 EGG42221.1 - 7.6e-08 32.0 0.2 8.7e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Acyl_transf_3 PF01757.17 EGG42222.1 - 0.46 9.2 26.3 0.27 10.0 11.0 2.1 1 1 1 2 2 2 0 Acyltransferase family DUF2324 PF10086.4 EGG42222.1 - 9.5 5.3 9.9 0.41 9.8 0.8 2.3 2 1 0 2 2 2 0 Putative membrane peptidase family (DUF2324) CBS PF00571.23 EGG42224.1 - 2e-41 139.5 5.8 5.5e-10 38.8 0.1 4.3 4 0 0 4 4 4 4 CBS domain Staphostatin_A PF09022.5 EGG42224.1 - 0.071 12.9 1.6 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Staphostatin A PepSY PF03413.14 EGG42225.1 - 0.04 14.5 0.4 0.06 13.9 0.2 1.6 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Pyrophosphatase PF00719.14 EGG42226.1 - 2.7e-58 195.8 0.1 3.2e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Peptidase_M3 PF01432.15 EGG42227.1 - 9e-46 156.8 0.4 3.8e-45 154.7 0.3 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.5 EGG42227.1 - 1.4e-07 31.4 4.8 1.8e-07 31.0 0.1 3.4 5 0 0 5 5 5 1 Oligopeptidase F DUF955 PF06114.8 EGG42227.1 - 0.0011 18.6 0.1 0.0031 17.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF955) Peptidase_MA_2 PF13485.1 EGG42227.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Peptidase MA superfamily DUF3198 PF11433.3 EGG42227.1 - 0.023 14.5 0.7 1.3 8.9 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3198) Zn_peptidase_2 PF04298.7 EGG42227.1 - 0.13 11.5 0.2 0.3 10.3 0.1 1.5 1 1 0 1 1 1 0 Putative neutral zinc metallopeptidase Syntaxin PF00804.20 EGG42227.1 - 0.96 9.6 9.1 0.8 9.9 0.2 3.6 3 1 0 3 3 3 0 Syntaxin PvlArgDC PF01862.11 EGG42229.1 - 2.7e-61 205.9 0.0 3e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Abi PF02517.11 EGG42230.1 - 0.0083 16.2 2.7 0.0083 16.2 1.9 3.1 2 1 1 3 3 3 1 CAAX protease self-immunity DUF2232 PF09991.4 EGG42231.1 - 0.013 14.4 0.3 0.014 14.4 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Tetraspannin PF00335.15 EGG42231.1 - 0.042 13.1 0.4 0.042 13.1 0.3 1.1 1 0 0 1 1 1 0 Tetraspanin family PgaD PF13994.1 EGG42231.1 - 0.046 13.2 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein Brevenin PF03032.10 EGG42231.1 - 5 7.0 5.2 0.88 9.4 1.0 1.6 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family Thioredoxin_4 PF13462.1 EGG42232.1 - 3.8e-41 140.8 0.2 6.8e-41 139.9 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.15 EGG42232.1 - 1.5e-20 73.6 0.5 1.4e-18 67.1 0.3 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EGG42232.1 - 4e-09 36.6 0.0 1.6e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Phi-29_GP16_7 PF06720.6 EGG42232.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 DEAD PF00270.24 EGG42233.1 - 1.5e-12 47.3 0.1 1.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD PF00270.24 EGG42234.1 - 3e-30 104.9 0.0 1.5e-27 96.1 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG42234.1 - 5.6e-26 90.2 0.0 8.7e-25 86.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EGG42234.1 - 0.0079 15.2 0.4 0.033 13.2 0.1 2.0 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit His_Phos_1 PF00300.17 EGG42234.1 - 0.011 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Helicase_C_2 PF13307.1 EGG42234.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Helicase C-terminal domain AsnC_trans_reg PF01037.16 EGG42235.1 - 1.6e-08 34.1 0.1 1.7e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 AsnC family GYD PF08734.6 EGG42235.1 - 0.00032 20.3 0.1 0.00034 20.2 0.0 1.1 1 0 0 1 1 1 1 GYD domain DHO_dh PF01180.16 EGG42235.1 - 0.097 11.6 0.5 0.12 11.3 0.3 1.0 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase TPP_enzyme_N PF02776.13 EGG42236.1 - 2e-55 186.8 0.0 3.3e-53 179.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGG42236.1 - 1.7e-39 134.8 0.0 5.4e-39 133.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGG42236.1 - 2.9e-29 101.5 0.2 7.1e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EGG42236.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Hormone_1 PF00103.15 EGG42237.1 - 0.096 12.0 2.6 0.095 12.0 1.8 1.2 1 0 0 1 1 1 0 Somatotropin hormone family Mod_r PF07200.8 EGG42237.1 - 0.13 12.2 5.7 0.2 11.5 0.7 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MRP-L28 PF09812.4 EGG42237.1 - 0.17 11.6 1.9 0.45 10.3 1.3 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 Toxin_52 PF15605.1 EGG42237.1 - 0.24 11.3 3.4 1.1 9.1 0.2 2.0 1 1 1 2 2 2 0 Putative toxin 52 Bromodomain PF00439.20 EGG42237.1 - 0.67 9.9 3.4 2.8 7.9 2.0 2.2 1 1 0 1 1 1 0 Bromodomain DUF972 PF06156.8 EGG42237.1 - 0.82 10.0 6.0 0.36 11.1 1.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EGG42237.1 - 1.3 8.5 5.3 0.71 9.3 1.5 2.2 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 EGG42237.1 - 2.3 8.2 5.9 2.5 8.1 2.2 2.4 1 1 1 2 2 2 0 bZIP transcription factor IQ-like PF15157.1 EGG42237.1 - 2.4 8.4 5.1 1.1 9.5 1.2 1.8 1 1 1 2 2 2 0 IQ-like CCDC-167 PF15188.1 EGG42237.1 - 5.2 7.0 9.4 19 5.2 6.4 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Amidohydro_2 PF04909.9 EGG42238.1 - 7.3e-38 130.6 0.0 8.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Trp_syntA PF00290.15 EGG42238.1 - 0.064 11.7 0.0 0.16 10.4 0.0 1.7 1 0 0 1 1 1 0 Tryptophan synthase alpha chain YtzH PF14165.1 EGG42238.1 - 0.069 13.3 0.1 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 YtzH-like protein Acetyltransf_9 PF13527.1 EGG42239.1 - 3.5e-07 30.1 0.0 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGG42239.1 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGG42239.1 - 0.00071 19.6 0.0 0.023 14.8 0.0 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGG42239.1 - 0.0053 16.8 0.0 0.026 14.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3901 PF13040.1 EGG42240.1 - 0.36 10.1 2.4 0.41 9.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) SHOCT PF09851.4 EGG42241.1 - 8.6e-09 34.5 4.4 1.4e-08 33.9 3.0 1.3 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.7 EGG42241.1 - 0.0067 16.1 0.1 0.0071 16.1 0.1 1.2 1 0 0 1 1 1 1 Gas vesicle protein G DMAP_binding PF06464.6 EGG42241.1 - 0.14 12.7 2.4 0.15 12.6 1.1 1.5 1 1 0 1 1 1 0 DMAP1-binding Domain Coiled-coil_56 PF09813.4 EGG42242.1 - 0.036 14.0 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 FA_desaturase PF00487.19 EGG42242.1 - 0.68 9.3 4.7 0.3 10.4 1.8 1.4 1 1 0 1 1 1 0 Fatty acid desaturase MS_channel PF00924.13 EGG42243.1 - 3.8e-11 42.7 1.8 7.3e-11 41.7 1.3 1.4 1 1 0 1 1 1 1 Mechanosensitive ion channel DUF768 PF05589.6 EGG42244.1 - 0.023 14.6 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF768) MS_channel PF00924.13 EGG42245.1 - 2.8e-28 98.6 0.0 6.3e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF1774 PF08611.5 EGG42245.1 - 0.059 13.5 0.8 0.18 11.9 0.6 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) Radical_SAM PF04055.16 EGG42246.1 - 6e-06 26.5 0.2 3.1e-05 24.2 0.1 2.5 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 EGG42246.1 - 5.6e-05 23.1 0.0 0.00023 21.1 0.0 2.0 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EGG42246.1 - 0.00086 19.4 0.1 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Gln-synt_C PF00120.19 EGG42247.1 - 2.2e-81 272.8 0.0 2.7e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGG42247.1 - 1e-23 82.6 0.1 2.2e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Response_reg PF00072.19 EGG42248.1 - 1.8e-09 37.6 0.0 2.1e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Polysacc_synt_4 PF04669.8 EGG42248.1 - 0.014 14.8 0.2 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis Toxin_56 PF15534.1 EGG42248.1 - 0.014 15.8 0.1 0.82 10.2 0.0 2.4 2 0 0 2 2 2 0 Putative toxin 56 DUF1176 PF06674.6 EGG42249.1 - 0.00031 19.9 1.3 0.00048 19.3 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1176) ASL_C PF08328.6 EGG42249.1 - 1.5 8.6 5.2 1 9.2 2.3 1.6 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Na_H_Exchanger PF00999.16 EGG42250.1 - 8.7e-57 192.3 54.9 1.1e-56 191.9 38.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CBS PF00571.23 EGG42250.1 - 2.8e-13 49.4 0.0 1.8e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF1413 PF07205.6 EGG42252.1 - 0.074 12.6 0.2 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) DUF3294 PF07957.6 EGG42253.1 - 0.055 12.9 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) FAINT PF04385.10 EGG42253.1 - 0.11 12.3 0.2 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function, DUF529 Thioredox_DsbH PF03190.10 EGG42256.1 - 8.2e-77 256.5 0.1 1.5e-76 255.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EGG42256.1 - 9.2e-14 51.2 0.1 1.9e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 EGG42256.1 - 1.4e-09 37.5 4.3 0.12 11.6 0.0 4.3 4 0 0 4 4 4 3 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 EGG42256.1 - 1.8e-06 27.2 0.1 0.12 11.4 0.0 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EGG42256.1 - 0.00023 19.5 0.2 0.88 7.7 0.0 3.1 2 1 1 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Thioredoxin_2 PF13098.1 EGG42256.1 - 0.00031 20.9 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_76 PF03663.9 EGG42256.1 - 0.00061 19.2 0.1 0.52 9.6 0.0 3.0 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.6 EGG42256.1 - 0.0014 17.7 0.2 6.9 5.5 0.0 3.5 2 1 1 3 3 3 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) LANC_like PF05147.8 EGG42256.1 - 0.002 16.7 0.5 0.82 8.1 0.0 4.1 4 1 1 5 5 5 1 Lanthionine synthetase C-like protein PP_kinase_N PF13089.1 EGG42257.1 - 0.062 13.4 0.4 0.068 13.2 0.2 1.1 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain Anp1 PF03452.9 EGG42257.1 - 0.2 10.7 1.5 0.22 10.6 1.0 1.0 1 0 0 1 1 1 0 Anp1 Viral_env_E26 PF11050.3 EGG42257.1 - 0.43 9.7 3.8 0.51 9.5 2.6 1.3 1 1 0 1 1 1 0 Virus envelope protein E26 Sds3 PF08598.6 EGG42257.1 - 0.91 9.0 4.8 0.69 9.4 2.0 1.6 1 1 1 2 2 2 0 Sds3-like EamA PF00892.15 EGG42258.1 - 8.1e-38 129.3 31.6 1.6e-20 73.4 8.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EGG42258.1 - 1.3e-13 51.1 27.9 7e-08 32.6 6.3 2.8 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EGG42258.1 - 0.0023 17.0 3.2 0.0023 17.0 2.2 2.5 2 1 0 2 2 2 1 Nucleotide-sugar transporter UPF0546 PF10639.4 EGG42258.1 - 0.0058 16.4 14.6 0.0061 16.3 1.1 2.5 2 2 0 2 2 2 2 Uncharacterised protein family UPF0546 TPT PF03151.11 EGG42258.1 - 0.019 14.6 31.8 0.13 11.8 8.8 3.3 2 2 0 2 2 2 0 Triose-phosphate Transporter family HTH_24 PF13412.1 EGG42260.1 - 9.2e-06 24.9 1.9 2.3e-05 23.6 1.3 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EGG42260.1 - 0.00014 21.3 3.7 0.00047 19.6 2.6 1.9 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain DM13 PF10517.4 EGG42262.1 - 8.6e-19 67.9 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 Med9 PF07544.8 EGG42263.1 - 0.00019 21.1 9.0 0.47 10.2 1.0 3.7 2 2 1 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 TBPIP PF07106.8 EGG42263.1 - 0.00052 19.5 8.0 0.12 11.9 1.7 2.7 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EGG42263.1 - 0.00058 19.5 4.3 0.072 12.6 0.9 2.5 2 0 0 2 2 2 2 IncA protein CENP-F_leu_zip PF10473.4 EGG42263.1 - 0.0011 18.7 5.7 0.12 12.2 1.2 2.4 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 EGG42263.1 - 0.0019 17.9 8.0 0.4 10.4 0.3 4.2 4 0 0 4 4 4 1 Prefoldin subunit ATG16 PF08614.6 EGG42263.1 - 0.0021 17.9 8.1 0.22 11.3 0.9 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Saf-Nte_pilin PF09460.5 EGG42263.1 - 0.0056 16.4 3.2 1.7 8.4 0.1 2.4 2 0 0 2 2 2 2 Saf-pilin pilus formation protein FlaC_arch PF05377.6 EGG42263.1 - 0.042 13.7 10.5 1.7 8.6 0.3 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 EGG42263.1 - 0.043 14.2 7.0 0.95 9.9 0.4 3.5 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.16 EGG42263.1 - 0.054 13.7 1.2 2.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Spectrin repeat HSBP1 PF06825.7 EGG42263.1 - 0.058 12.9 0.4 0.58 9.7 0.1 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF4094 PF13334.1 EGG42263.1 - 0.084 13.2 8.4 1.6 9.1 0.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) DUF4363 PF14276.1 EGG42263.1 - 0.098 12.3 1.8 7.7 6.2 0.0 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4363) Phage_GP20 PF06810.6 EGG42263.1 - 0.14 11.5 8.5 0.2 11.0 0.8 2.7 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF848 PF05852.6 EGG42263.1 - 0.17 11.7 7.6 0.24 11.2 1.1 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FliJ PF02050.11 EGG42263.1 - 0.22 11.5 1.9 8 6.5 0.0 2.8 2 1 1 3 3 3 0 Flagellar FliJ protein Tropomyosin_1 PF12718.2 EGG42263.1 - 0.22 11.3 10.0 0.26 11.1 0.2 2.6 2 2 0 2 2 2 0 Tropomyosin like DUF1192 PF06698.6 EGG42263.1 - 0.48 10.2 6.9 22 4.9 0.3 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF1192) DUF1845 PF08900.6 EGG42263.1 - 0.51 9.5 2.7 4.9 6.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1845) TMF_DNA_bd PF12329.3 EGG42263.1 - 0.88 9.4 14.9 4.1 7.2 0.8 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 EGG42263.1 - 0.93 9.5 12.0 0.94 9.5 1.4 3.5 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 EGG42263.1 - 1.1 9.4 7.6 7.3 6.8 0.7 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ORF6C PF10552.4 EGG42263.1 - 1.8 8.3 6.0 16 5.2 0.3 2.8 2 2 0 2 2 2 0 ORF6C domain DUF4391 PF14335.1 EGG42263.1 - 1.8 7.9 10.9 0.14 11.4 0.5 3.1 3 1 0 3 3 2 0 Domain of unknown function (DUF4391) DUF1664 PF07889.7 EGG42263.1 - 1.8 8.3 9.0 2.2 8.0 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LUC7 PF03194.10 EGG42263.1 - 2.7 7.4 6.1 1.4 8.3 0.6 2.2 2 0 0 2 2 2 0 LUC7 N_terminus CCDC-167 PF15188.1 EGG42263.1 - 6.3 6.8 8.4 56 3.7 0.1 3.3 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4200 PF13863.1 EGG42263.1 - 6.7 6.6 13.3 2.1 8.2 0.4 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EGG42263.1 - 8 4.1 8.9 2.9 5.6 1.0 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family z-alpha PF02295.12 EGG42265.1 - 0.33 10.7 1.8 2 8.2 0.0 3.1 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain Pilin PF00114.14 EGG42265.1 - 1.1 10.0 4.0 4.7 7.9 0.2 2.7 3 0 0 3 3 3 0 Pilin (bacterial filament) Seryl_tRNA_N PF02403.17 EGG42265.1 - 4.5 7.3 11.2 1.4 8.9 2.4 2.9 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Response_reg PF00072.19 EGG42266.1 - 3.7e-22 78.4 0.8 4.2e-22 78.2 0.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain LMWPc PF01451.16 EGG42267.1 - 2.9e-27 95.6 0.1 3.5e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ADH_N PF08240.7 EGG42268.1 - 1.6e-18 66.4 0.3 1.9e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG42270.1 - 3.8e-07 29.7 0.0 4.1e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGG42271.1 - 3.5e-05 24.6 0.0 3.6e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CLU_N PF15044.1 EGG42271.1 - 0.0016 18.5 0.0 0.002 18.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term LemA PF04011.7 EGG42271.1 - 0.054 12.5 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 LemA family AAA_33 PF13671.1 EGG42272.1 - 5.5e-17 61.9 0.0 6.5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG42272.1 - 0.0001 23.1 0.1 0.00014 22.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGG42272.1 - 0.0023 17.2 0.0 0.0026 16.9 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EGG42272.1 - 0.0028 16.7 0.1 0.0071 15.4 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin DUF3791 PF12668.2 EGG42272.1 - 0.0054 16.3 0.9 0.013 15.0 0.3 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3791) AAA_18 PF13238.1 EGG42272.1 - 0.012 15.8 3.7 0.03 14.6 2.6 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EGG42272.1 - 0.08 12.3 0.5 0.82 9.0 0.4 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGG42272.1 - 0.15 12.2 2.0 1.3 9.1 1.4 2.2 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EGG42272.1 - 0.17 11.4 0.8 0.48 9.9 0.1 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Molybdop_Fe4S4 PF04879.11 EGG42273.1 - 0.0052 16.5 8.0 0.38 10.5 0.6 2.2 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Fe4S4 domain DNA_RNApol_7kD PF03604.8 EGG42273.1 - 0.0078 15.6 15.4 0.39 10.2 2.7 2.8 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_6 PF14599.1 EGG42273.1 - 0.03 14.1 9.7 0.53 10.1 1.0 2.8 2 2 0 2 2 2 0 Zinc-ribbon DZR PF12773.2 EGG42273.1 - 0.052 13.3 13.9 0.57 10.0 2.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF4001 PF13165.1 EGG42273.1 - 0.22 11.2 10.0 1.7 8.3 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4001) Stig1 PF04885.8 EGG42273.1 - 0.24 11.6 4.4 9.7 6.3 0.2 2.4 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 CpXC PF14353.1 EGG42273.1 - 0.32 10.9 4.1 7.8 6.4 0.3 2.3 2 0 0 2 2 2 0 CpXC protein NUC205 PF08168.6 EGG42273.1 - 0.34 10.3 1.5 19 4.7 0.1 2.2 2 0 0 2 2 2 0 NUC205 domain LIM PF00412.17 EGG42273.1 - 0.87 9.7 13.0 3.5 7.7 1.8 2.2 2 0 0 2 2 2 0 LIM domain C1_1 PF00130.17 EGG42273.1 - 0.94 9.2 11.1 4.3 7.1 1.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EGG42273.1 - 5.6 6.9 17.3 6.9 6.7 3.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 EGG42273.1 - 7.9 6.2 10.4 5.7 6.6 0.8 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 EGG42273.1 - 8.4 6.1 10.8 5.1 6.8 0.3 2.9 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like DUF2196 PF09962.4 EGG42274.1 - 4.5e-29 100.0 1.9 4.9e-29 99.8 1.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) PhoU PF01895.14 EGG42275.1 - 2e-20 73.0 5.6 3.1e-11 43.5 1.2 2.2 2 0 0 2 2 2 2 PhoU domain Sec66 PF09802.4 EGG42275.1 - 0.091 12.1 0.2 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 ABC_tran PF00005.22 EGG42276.1 - 1.3e-30 106.5 0.0 1.8e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGG42276.1 - 5.5e-16 59.3 0.0 4.7e-09 36.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EGG42276.1 - 2.3e-10 40.0 0.1 4.5e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGG42276.1 - 1.2e-07 31.1 1.5 0.0046 16.0 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGG42276.1 - 2.4e-05 24.4 0.1 8.8e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGG42276.1 - 9.7e-05 22.7 0.4 0.0002 21.7 0.3 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGG42276.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGG42276.1 - 0.00068 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.15 EGG42276.1 - 0.0032 16.2 0.0 0.0044 15.7 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Rad17 PF03215.10 EGG42276.1 - 0.004 15.9 0.0 0.0055 15.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EGG42276.1 - 0.0049 16.5 0.6 0.08 12.6 0.4 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EGG42276.1 - 0.0051 16.8 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EGG42276.1 - 0.01 15.3 0.5 0.088 12.2 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EGG42276.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGG42276.1 - 0.015 14.8 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EGG42276.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGG42276.1 - 0.019 15.7 0.3 0.045 14.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 EGG42276.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.1 EGG42276.1 - 0.042 13.5 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EGG42276.1 - 0.046 13.9 1.6 0.43 10.7 0.2 2.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGG42276.1 - 0.057 13.0 0.1 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EGG42276.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EGG42276.1 - 0.062 13.2 0.2 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGG42276.1 - 0.062 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGG42276.1 - 0.1 12.0 0.1 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGG42276.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Epimerase_2 PF02350.14 EGG42276.1 - 0.14 10.8 0.4 6.3 5.4 0.0 2.1 1 1 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase BPD_transp_1 PF00528.17 EGG42277.1 - 8.5e-18 64.5 21.5 1e-17 64.2 10.8 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF3270 PF11674.3 EGG42277.1 - 0.96 9.4 4.2 0.51 10.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) BPD_transp_1 PF00528.17 EGG42278.1 - 5.3e-17 61.9 15.9 5.3e-17 61.9 11.0 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2583 PF10762.4 EGG42278.1 - 7.7 6.7 6.8 15 5.8 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) FtsX PF02687.16 EGG42278.1 - 8.9 6.1 30.4 6.8 6.4 6.4 4.0 2 1 1 3 3 3 0 FtsX-like permease family PhoU PF01895.14 EGG42279.1 - 1.8e-23 82.8 12.4 2e-17 63.3 2.2 2.5 2 0 0 2 2 2 2 PhoU domain Antitoxin-MazE PF04014.13 EGG42279.1 - 9.4e-06 25.2 0.0 2.5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Antidote-toxin recognition MazE SeqA PF03925.8 EGG42279.1 - 0.0035 17.0 1.5 0.0035 17.0 1.0 2.2 2 0 0 2 2 2 1 SeqA protein PhoU_div PF01865.11 EGG42279.1 - 0.017 14.2 12.8 0.013 14.7 5.5 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF47 DUF643 PF04867.7 EGG42279.1 - 0.27 11.6 5.8 0.1 12.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF2312 PF10073.4 EGG42279.1 - 1.5 8.2 6.5 6.8 6.1 0.5 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) PBP_like_2 PF12849.2 EGG42281.1 - 1.1e-50 172.6 1.1 1.6e-50 172.1 0.8 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.20 EGG42281.1 - 1.2e-13 51.5 1.1 1.4e-13 51.2 0.3 1.6 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.2 EGG42281.1 - 5.6e-08 31.9 0.0 2.5e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 PBP superfamily domain DUF859 PF05895.7 EGG42281.1 - 0.018 13.3 0.0 0.036 12.3 0.0 1.4 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) MutS_II PF05188.12 EGG42282.1 - 0.011 15.7 0.1 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 MutS domain II DUF777 PF05606.6 EGG42282.1 - 0.02 14.0 0.2 0.03 13.5 0.1 1.3 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) Lar_restr_allev PF14354.1 EGG42283.1 - 0.011 16.0 2.5 0.034 14.4 1.7 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 EGG42283.1 - 0.023 14.3 5.2 0.036 13.7 2.2 2.1 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_5 PF13719.1 EGG42283.1 - 0.025 14.1 3.3 0.063 12.8 2.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGG42283.1 - 0.038 13.3 5.6 0.096 12.0 3.9 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2310 PF10071.4 EGG42283.1 - 0.067 12.1 0.4 0.11 11.4 0.3 1.3 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) zf-CSL PF05207.8 EGG42283.1 - 0.082 12.4 2.9 0.18 11.3 2.0 1.6 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.8 EGG42283.1 - 0.39 10.4 4.5 0.83 9.3 3.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Cys_rich_CPCC PF14206.1 EGG42283.1 - 0.56 9.8 4.1 0.41 10.2 1.6 1.7 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-TFIIB PF13453.1 EGG42283.1 - 1 8.5 9.9 0.25 10.5 4.0 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger DNA_RNApol_7kD PF03604.8 EGG42283.1 - 1.3 8.5 10.3 0.46 9.9 4.4 2.3 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF2387 PF09526.5 EGG42283.1 - 1.5 8.7 5.4 1.4 8.8 2.4 1.9 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-ISL3 PF14690.1 EGG42283.1 - 1.7 8.7 5.3 1.4 9.0 0.2 2.5 3 0 0 3 3 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prok-RING_1 PF14446.1 EGG42283.1 - 2.2 8.0 8.8 4.5 7.0 3.0 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 TFIIS_C PF01096.13 EGG42283.1 - 2.7 7.6 6.7 6.4 6.4 0.1 2.7 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.1 EGG42283.1 - 2.8 7.7 8.1 0.31 10.7 2.5 1.8 2 0 0 2 2 1 0 zinc-ribbon domain DZR PF12773.2 EGG42283.1 - 4.4 7.1 9.0 17 5.3 5.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EGG42283.1 - 5.1 7.2 8.6 2.1 8.5 4.0 2.0 2 1 0 2 2 1 0 Zinc-binding domain of primase-helicase IBR PF01485.16 EGG42283.1 - 6.9 6.6 10.0 1 9.3 1.6 2.5 2 1 1 3 3 3 0 IBR domain DUF4097 PF13349.1 EGG42284.1 - 0.017 14.7 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Plus-3 PF03126.13 EGG42284.1 - 0.067 13.2 0.1 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Plus-3 domain DUF2177 PF09945.4 EGG42285.1 - 0.013 15.4 8.1 0.19 11.7 2.2 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2177) DUF2583 PF10762.4 EGG42286.1 - 0.015 15.3 4.2 0.03 14.4 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) SdpI PF13630.1 EGG42286.1 - 0.017 14.8 4.8 0.042 13.5 3.3 1.7 1 1 0 1 1 1 0 SdpI/YhfL protein family DUF2101 PF09874.4 EGG42286.1 - 0.025 14.0 0.4 0.029 13.8 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF4401 PF14351.1 EGG42286.1 - 0.037 13.0 0.6 0.047 12.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF1469 PF07332.6 EGG42286.1 - 0.075 12.7 0.5 0.1 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF3040 PF11239.3 EGG42286.1 - 0.22 11.5 8.3 1.5 8.9 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Neurensin PF14927.1 EGG42286.1 - 1.7 8.0 6.8 6.4 6.1 4.7 1.9 1 1 0 1 1 1 0 Neurensin AsnC_trans_reg PF01037.16 EGG42287.1 - 2.2e-10 40.0 0.1 2.4e-10 39.9 0.1 1.0 1 0 0 1 1 1 1 AsnC family TruD PF01142.13 EGG42288.1 - 1.7e-65 221.1 0.4 2e-65 220.9 0.3 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) SGL PF08450.7 EGG42289.1 - 4e-09 36.2 1.3 0.13 11.6 0.0 4.5 1 1 1 4 4 4 3 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EGG42289.1 - 1.3e-05 24.9 0.0 0.0026 17.6 0.0 3.2 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.11 EGG42289.1 - 0.052 13.5 0.0 12 5.9 0.0 3.3 2 1 1 3 3 3 0 Strictosidine synthase Reg_prop PF07494.6 EGG42289.1 - 0.055 13.4 6.5 20 5.6 0.0 4.9 5 0 0 5 5 5 0 Two component regulator propeller PQQ_3 PF13570.1 EGG42289.1 - 0.061 13.6 0.0 11 6.4 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain EF_assoc_1 PF08355.7 EGG42289.1 - 0.077 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 EF hand associated PTH2 PF01981.11 EGG42290.1 - 1.2e-43 147.4 0.0 1.3e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 zf-ribbon_3 PF13248.1 EGG42291.1 - 0.11 11.7 0.4 0.11 11.7 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain PolC_DP2 PF03833.8 EGG42291.1 - 0.34 8.5 12.0 0.38 8.3 8.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1610 PF07754.6 EGG42291.1 - 0.37 10.9 26.1 0.32 11.1 6.4 3.5 3 2 0 3 3 3 0 Domain of unknown function (DUF1610) EF1_GNE PF00736.14 EGG42292.1 - 2.9e-19 68.5 0.7 3.2e-19 68.3 0.5 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF4390 PF14334.1 EGG42292.1 - 0.093 11.9 0.0 7.4 5.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) AAA PF00004.24 EGG42293.1 - 2.3e-91 302.8 0.2 3.5e-48 163.1 0.0 3.1 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGG42293.1 - 7e-26 90.0 0.7 2.8e-25 88.0 0.5 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EGG42293.1 - 3.7e-15 55.6 0.2 1.7e-08 33.8 0.0 2.9 3 1 1 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGG42293.1 - 1.4e-13 51.7 0.2 9.8e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGG42293.1 - 3e-13 50.0 0.0 1.1e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EGG42293.1 - 6.9e-13 48.6 0.0 5.2e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGG42293.1 - 1.7e-12 47.6 0.3 0.0051 16.9 0.0 4.6 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EGG42293.1 - 2.1e-12 47.4 0.0 0.00034 20.6 0.0 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EGG42293.1 - 3.5e-11 42.9 0.6 0.00015 21.5 0.0 4.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EGG42293.1 - 4e-10 39.7 0.1 0.0008 19.1 0.0 3.6 2 1 1 3 3 3 3 Archaeal ATPase AAA_18 PF13238.1 EGG42293.1 - 8.6e-10 39.0 0.2 0.0011 19.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EGG42293.1 - 1.4e-09 38.1 0.0 0.0014 18.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase CDC48_2 PF02933.12 EGG42293.1 - 1e-08 34.6 0.3 3.6e-08 32.9 0.1 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.1 EGG42293.1 - 1.2e-08 34.9 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EGG42293.1 - 1.4e-08 35.0 0.1 0.0088 16.3 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EGG42293.1 - 1.6e-08 34.1 4.9 0.1 11.9 0.1 4.7 2 2 2 5 5 5 3 AAA domain Sigma54_activ_2 PF14532.1 EGG42293.1 - 1.8e-07 31.3 0.0 0.018 15.0 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EGG42293.1 - 2.4e-07 30.8 0.0 0.023 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGG42293.1 - 3.1e-07 29.9 0.1 0.03 13.7 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGG42293.1 - 4.1e-07 29.3 0.0 0.015 14.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 EGG42293.1 - 8.2e-07 28.3 0.4 0.016 14.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 EGG42293.1 - 4.3e-06 26.4 0.1 0.14 11.6 0.0 3.3 2 1 1 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain TIP49 PF06068.8 EGG42293.1 - 4.4e-06 25.6 0.1 0.013 14.2 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EGG42293.1 - 5.9e-06 25.9 1.0 0.079 12.7 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain Rad17 PF03215.10 EGG42293.1 - 8.2e-06 24.7 0.0 0.073 11.7 0.0 2.5 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 EGG42293.1 - 1.3e-05 24.7 0.0 1 8.8 0.0 3.9 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_24 PF13479.1 EGG42293.1 - 3.2e-05 23.6 0.1 0.31 10.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EGG42293.1 - 4.5e-05 22.6 0.8 0.39 9.7 0.0 3.6 2 1 1 3 3 3 2 KaiC NACHT PF05729.7 EGG42293.1 - 6e-05 22.7 0.8 1.8 8.1 0.0 3.6 4 0 0 4 4 3 2 NACHT domain PhoH PF02562.11 EGG42293.1 - 0.00027 20.2 0.6 1.5 7.9 0.1 3.7 3 0 0 3 3 3 1 PhoH-like protein Viral_helicase1 PF01443.13 EGG42293.1 - 0.00031 20.3 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EGG42293.1 - 0.0005 19.1 0.0 0.68 8.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EGG42293.1 - 0.00099 18.7 0.1 2.5 7.7 0.0 3.2 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EGG42293.1 - 0.0012 18.0 0.0 1.9 7.6 0.0 3.3 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Cytidylate_kin2 PF13189.1 EGG42293.1 - 0.0015 18.5 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 EGG42293.1 - 0.0015 18.4 0.1 2 8.2 0.0 3.0 3 0 0 3 3 3 1 Shikimate kinase Parvo_NS1 PF01057.12 EGG42293.1 - 0.0018 17.2 0.1 1.5 7.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 EGG42293.1 - 0.0023 17.7 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EGG42293.1 - 0.0038 16.8 0.0 0.92 9.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EGG42293.1 - 0.0062 15.5 0.0 1.2 8.1 0.0 3.0 2 1 1 3 3 3 1 KAP family P-loop domain DUF815 PF05673.8 EGG42293.1 - 0.0069 15.3 0.0 4.9 5.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EGG42293.1 - 0.012 14.4 0.7 4.1 6.1 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.1 EGG42293.1 - 0.033 14.5 0.0 3.7 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGG42293.1 - 0.036 13.6 0.1 7 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 EGG42293.1 - 0.047 12.8 0.1 0.51 9.4 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KTI12 PF08433.5 EGG42293.1 - 0.056 12.6 0.0 10 5.2 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EGG42293.1 - 0.066 12.9 1.0 16 5.1 0.0 3.7 2 2 1 3 3 3 0 NTPase AAA_21 PF13304.1 EGG42293.1 - 0.076 12.9 1.1 24 4.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EGG42293.1 - 0.18 10.2 0.0 6.7 5.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TF_Zn_Ribbon PF08271.7 EGG42295.1 - 0.073 12.3 5.6 0.095 12.0 0.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding zf-CCHC_4 PF14392.1 EGG42295.1 - 0.11 12.1 0.3 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 Zinc knuckle DZR PF12773.2 EGG42295.1 - 0.22 11.3 4.9 0.28 11.0 3.4 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-LSD1 PF06943.7 EGG42295.1 - 0.24 11.0 4.1 0.3 10.7 0.5 2.3 2 0 0 2 2 2 0 LSD1 zinc finger zf-FCS PF06467.9 EGG42295.1 - 0.59 9.8 0.2 0.59 9.8 0.1 2.7 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Fer4_10 PF13237.1 EGG42295.1 - 2.9 7.7 6.9 4.7 7.0 4.8 1.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain C1_1 PF00130.17 EGG42295.1 - 3.2 7.5 8.8 1.7 8.4 3.9 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HicB PF05534.7 EGG42296.1 - 0.018 14.5 0.1 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 HicB family UPF0137 PF03677.8 EGG42296.1 - 0.06 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) SurA_N PF09312.6 EGG42296.1 - 0.06 13.1 0.1 0.3 10.9 0.0 1.9 1 1 1 2 2 2 0 SurA N-terminal domain TauE PF01925.14 EGG42298.1 - 2.3e-46 158.2 36.6 2.6e-46 158.0 25.4 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Rhodanese PF00581.15 EGG42299.1 - 1e-25 90.2 0.0 1.1e-12 48.2 0.0 3.0 3 0 0 3 3 3 2 Rhodanese-like domain Lactamase_B PF00753.22 EGG42299.1 - 8.3e-24 84.3 0.8 1.4e-23 83.6 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.1 EGG42299.1 - 0.0034 16.8 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EGG42299.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain UbiA PF01040.13 EGG42303.1 - 1e-27 96.9 23.3 1.3e-27 96.6 16.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4231 PF14015.1 EGG42303.1 - 0.59 10.1 0.0 0.59 10.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF1129 PF06570.6 EGG42303.1 - 1.6 7.9 9.1 1.9 7.7 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Copper-bind PF00127.15 EGG42304.1 - 3e-15 56.2 1.0 6e-07 29.6 0.0 2.7 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EGG42304.1 - 7.5e-13 48.2 0.1 1.2e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain DUF2178 PF09946.4 EGG42304.1 - 2.7 7.7 9.9 0.41 10.4 3.7 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) Prok-JAB PF14464.1 EGG42305.1 - 1.3e-19 69.6 0.0 1.6e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 EGG42305.1 - 4.5e-12 45.7 0.0 6.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.10 EGG42305.1 - 0.003 17.2 0.3 0.0072 16.0 0.2 1.6 1 1 0 1 1 1 1 RadC-like JAB domain Toxin-JAB1 PF15659.1 EGG42305.1 - 0.0075 16.1 0.4 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 JAB-like toxin 1 DUF3461 PF11944.3 EGG42305.1 - 0.031 14.1 0.1 0.066 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) TylF PF05711.6 EGG42305.1 - 0.093 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Cyclophil_like PF04126.8 EGG42306.1 - 1.9e-38 130.7 0.0 2.1e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like DUF3830 PF12903.2 EGG42306.1 - 0.002 17.4 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) NSP2_assoc PF14758.1 EGG42306.1 - 0.078 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein Methyltransf_3 PF01596.12 EGG42307.1 - 6e-39 133.2 0.3 1.1e-38 132.3 0.2 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGG42307.1 - 9e-15 55.4 0.0 1.5e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG42307.1 - 1.2e-10 41.9 0.0 2.7e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EGG42307.1 - 8.1e-08 32.0 0.1 2.9e-07 30.2 0.0 1.9 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGG42307.1 - 1e-07 31.6 0.3 1.7e-07 30.9 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EGG42307.1 - 8.3e-06 25.2 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 EGG42307.1 - 1.5e-05 24.9 0.0 5.6e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EGG42307.1 - 0.00012 21.3 0.0 0.00014 21.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 EGG42307.1 - 0.00061 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EGG42307.1 - 0.0032 16.8 0.1 0.0052 16.1 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EGG42307.1 - 0.0073 15.6 0.0 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGG42307.1 - 0.0078 16.6 0.0 0.049 14.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG42307.1 - 0.0084 16.4 0.0 0.099 13.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EGG42307.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GCD14 PF08704.5 EGG42307.1 - 0.033 13.7 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF1975 PF09318.5 EGG42308.1 - 0.00043 19.9 0.0 0.00073 19.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1975) ARD PF03079.9 EGG42308.1 - 0.1 12.5 0.2 0.15 11.9 0.1 1.3 1 1 0 1 1 1 0 ARD/ARD' family HgmA PF04209.8 EGG42308.1 - 0.13 10.6 0.0 0.14 10.5 0.0 1.0 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.1 EGG42310.1 - 3e-55 187.4 56.4 3.7e-55 187.1 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGG42310.1 - 4.3e-47 160.5 52.1 5.4e-47 160.2 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EGG42310.1 - 1e-09 37.5 19.8 1e-09 37.5 13.7 2.5 1 1 1 3 3 3 1 Spore germination protein AA_permease_C PF13906.1 EGG42310.1 - 4e-05 23.4 2.2 4e-05 23.4 1.5 4.4 6 0 0 6 6 6 1 C-terminus of AA_permease DUF2238 PF09997.4 EGG42310.1 - 5.3 6.4 10.4 3.1 7.1 3.0 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) Usp PF00582.21 EGG42311.1 - 2.6e-07 30.9 0.0 3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF3896 PF13035.1 EGG42311.1 - 0.017 15.1 1.1 0.18 11.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) BofC_C PF08955.5 EGG42311.1 - 0.067 13.2 0.9 0.21 11.6 0.2 2.2 2 1 0 2 2 2 0 BofC C-terminal domain DUF3845 PF12956.2 EGG42311.1 - 0.098 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure DUF389 PF04087.9 EGG42312.1 - 6.4e-31 107.1 17.3 6.4e-31 107.1 12.0 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF389) DUF2024 PF09630.5 EGG42313.1 - 2.6e-39 132.7 1.3 2.9e-39 132.6 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) CCG PF02754.11 EGG42313.1 - 0.053 13.5 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich domain Cytochrom_NNT PF03264.9 EGG42313.1 - 0.053 12.9 0.4 0.055 12.8 0.3 1.1 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region H_PPase PF03030.11 EGG42315.1 - 9.4e-148 493.4 30.4 1.1e-147 493.2 21.0 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Citrate_synt PF00285.16 EGG42316.1 - 9.7e-139 462.0 0.0 1.1e-138 461.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DUF1940 PF09155.5 EGG42316.1 - 0.001 18.9 0.1 0.012 15.4 0.0 2.6 2 2 1 3 3 3 1 Domain of unknown function (DUF1940) FrhB_FdhB_N PF04422.8 EGG42316.1 - 0.05 13.4 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term DUF2439 PF10382.4 EGG42317.1 - 0.085 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) DUF2407_C PF13373.1 EGG42318.1 - 0.0086 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain ADH_N PF08240.7 EGG42319.1 - 5.4e-25 87.2 2.3 1.1e-24 86.2 1.6 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG42319.1 - 7.1e-21 74.1 0.0 9.8e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGG42319.1 - 0.00052 20.8 0.0 0.00096 20.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ATP-synt_F PF01990.12 EGG42320.1 - 2.1e-15 56.8 0.0 2.3e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Trp_syntA PF00290.15 EGG42320.1 - 0.00014 20.5 0.0 0.00014 20.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain GTP-bdg_N PF13167.1 EGG42320.1 - 0.035 14.2 0.2 0.052 13.6 0.1 1.2 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal DUF4350 PF14258.1 EGG42320.1 - 0.079 13.1 0.1 0.31 11.2 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4350) DUF162 PF02589.10 EGG42320.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 UBA_3 PF09288.5 EGG42321.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF465 PF04325.8 EGG42322.1 - 0.019 14.6 0.5 0.03 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF327 PF03885.8 EGG42322.1 - 0.065 13.0 1.9 0.068 12.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Poty_coat PF00767.13 EGG42322.1 - 0.11 11.8 0.1 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Potyvirus coat protein Nol1_Nop2_Fmu_2 PF13636.1 EGG42323.1 - 0.028 14.5 0.0 0.04 13.9 0.0 1.3 1 1 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis SWIM PF04434.12 EGG42323.1 - 0.081 12.4 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 SWIM zinc finger Metallophos PF00149.23 EGG42324.1 - 3.4e-08 33.1 0.5 1.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGG42324.1 - 5.1e-06 26.4 0.0 1.4e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGG42324.1 - 0.0092 15.1 0.1 1.3 8.1 0.0 2.2 1 1 1 2 2 2 2 Metallophosphoesterase, calcineurin superfamily Epimerase_2 PF02350.14 EGG42324.1 - 0.035 12.8 0.0 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DNA_pol_E_B PF04042.11 EGG42324.1 - 0.069 12.3 0.1 0.3 10.3 0.0 2.0 2 1 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B CPSase_L_D2 PF02786.12 EGG42325.1 - 6e-103 342.6 0.0 1.4e-73 246.6 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EGG42325.1 - 7.4e-40 135.5 0.0 1.8e-39 134.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EGG42325.1 - 8.6e-37 126.6 0.0 1.5e-17 63.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG42325.1 - 2.6e-21 75.7 0.0 1.1e-12 47.3 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_chain PF00289.17 EGG42325.1 - 4.1e-19 68.7 0.4 2.1e-15 56.7 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp PF02222.17 EGG42325.1 - 2.9e-17 62.5 0.4 1.2e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG42325.1 - 2.1e-14 53.4 0.7 1.2e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 EGG42325.1 - 6e-14 51.7 0.3 6.5e-13 48.4 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain GARS_A PF01071.14 EGG42325.1 - 3.6e-10 39.7 0.2 0.00039 20.0 0.0 2.7 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EGG42325.1 - 1.1e-05 25.3 1.1 0.057 13.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain TrkA_N PF02254.13 EGG42325.1 - 0.0065 16.4 0.0 0.024 14.6 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain Vps5 PF09325.5 EGG42325.1 - 0.047 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Vps5 C terminal like CPSase_sm_chain PF00988.17 EGG42326.1 - 2e-43 147.0 0.0 6.8e-43 145.3 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EGG42326.1 - 8.2e-42 142.8 0.1 1.3e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG42326.1 - 2.4e-08 33.6 0.2 7.4e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 DUF3867 PF12983.2 EGG42326.1 - 0.029 14.3 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) AAA PF00004.24 EGG42327.1 - 4.2e-38 130.5 0.0 9.9e-38 129.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 EGG42327.1 - 3.9e-08 33.0 0.3 1.5e-07 31.1 0.1 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.9 EGG42327.1 - 2e-07 31.0 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGG42327.1 - 3.2e-06 27.3 0.0 1.5e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGG42327.1 - 1.1e-05 24.5 0.0 2.9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 EGG42327.1 - 2.3e-05 24.2 0.0 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.7 EGG42327.1 - 2.9e-05 23.2 0.0 9.5e-05 21.5 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 EGG42327.1 - 0.00014 21.5 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGG42327.1 - 0.00017 21.0 0.3 0.0031 16.9 0.2 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EGG42327.1 - 0.00039 20.3 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG42327.1 - 0.00052 20.0 0.0 0.034 14.1 0.0 2.7 1 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EGG42327.1 - 0.00074 19.4 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGG42327.1 - 0.0014 18.3 0.0 1.9 8.1 0.0 2.7 1 1 1 2 2 2 2 Archaeal ATPase AAA_17 PF13207.1 EGG42327.1 - 0.0024 18.6 0.0 0.0063 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGG42327.1 - 0.0036 17.0 0.1 0.016 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGG42327.1 - 0.0041 16.2 0.1 0.0094 15.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGG42327.1 - 0.0052 16.2 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGG42327.1 - 0.0059 16.3 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EGG42327.1 - 0.0078 15.8 0.0 0.026 14.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EGG42327.1 - 0.0079 14.9 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus KAP_NTPase PF07693.9 EGG42327.1 - 0.012 14.5 0.0 0.35 9.8 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain KaiC PF06745.8 EGG42327.1 - 0.037 13.1 0.1 1.7 7.6 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.1 EGG42327.1 - 0.039 14.2 0.2 0.16 12.2 0.0 2.2 2 1 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.12 EGG42327.1 - 0.09 11.6 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EGG42327.1 - 0.091 11.9 0.2 0.23 10.6 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 EGG42327.1 - 0.1 12.7 0.0 0.36 11.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 EGG42327.1 - 0.12 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EGG42327.1 - 0.14 11.7 0.2 0.39 10.3 0.0 1.8 2 0 0 2 2 1 0 NACHT domain DASH_Spc19 PF08287.6 EGG42328.1 - 0.014 15.0 0.5 0.014 15.0 0.3 1.6 2 1 0 2 2 2 0 Spc19 RVT_thumb PF06817.9 EGG42328.1 - 0.065 12.8 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase thumb domain TrmB PF01978.14 EGG42330.1 - 1.2e-17 63.3 0.4 9.4e-17 60.4 0.1 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 EGG42330.1 - 2.3e-05 23.5 0.2 3.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB DUF327 PF03885.8 EGG42330.1 - 0.036 13.9 0.5 0.036 13.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HTH_IclR PF09339.5 EGG42330.1 - 0.17 11.5 0.0 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain YjgF_endoribonc PF14588.1 EGG42331.1 - 6.4e-32 110.5 0.0 7e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 EGG42331.1 - 1.1e-22 80.0 0.0 1.4e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.12 EGG42331.1 - 0.012 15.3 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 BON domain DHHA1 PF02272.14 EGG42332.1 - 5.7e-12 45.1 1.4 1.4e-11 43.8 0.1 2.2 3 0 0 3 3 3 1 DHHA1 domain DHH PF01368.15 EGG42332.1 - 0.0013 18.4 3.7 0.0027 17.3 1.9 2.0 2 1 0 2 2 2 1 DHH family Response_reg PF00072.19 EGG42334.1 - 1.9e-19 69.7 0.2 2.2e-19 69.5 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain ORF6C PF10552.4 EGG42334.1 - 0.79 9.4 4.3 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 ORF6C domain Response_reg PF00072.19 EGG42335.1 - 5.5e-25 87.5 0.5 6.4e-25 87.3 0.3 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF2179 PF10035.4 EGG42335.1 - 0.094 12.3 0.5 0.22 11.1 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Response_reg PF00072.19 EGG42336.1 - 2.9e-24 85.2 0.1 3.4e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.19 EGG42337.1 - 2.3e-24 85.5 0.1 5.4e-24 84.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EGG42337.1 - 5.9e-19 67.8 0.3 1.6e-18 66.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 EGG42337.1 - 3e-11 42.9 0.4 3e-11 42.9 0.3 2.3 2 1 0 2 2 2 1 GHKL domain HisKA PF00512.20 EGG42337.1 - 2.8e-09 36.8 0.4 7.5e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 EGG42337.1 - 0.0054 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Response_reg PF00072.19 EGG42338.1 - 2.7e-23 82.1 0.3 3.1e-23 81.9 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 EGG42338.1 - 0.0024 17.7 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain SeleniumBinding PF11524.3 EGG42338.1 - 0.037 14.1 0.4 0.065 13.3 0.3 1.4 1 0 0 1 1 1 0 Selenium binding protein Response_reg PF00072.19 EGG42339.1 - 6.5e-20 71.2 0.1 7.4e-20 71.0 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.19 EGG42340.1 - 7.5e-22 77.4 0.2 8.6e-22 77.2 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 EGG42340.1 - 0.07 12.9 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain Phage_XkdX PF09693.5 EGG42340.1 - 0.085 12.3 0.6 0.57 9.7 0.1 2.3 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) 2-Hacid_dh_C PF02826.14 EGG42340.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 EGG42340.1 - 0.12 11.7 0.1 0.2 11.0 0.0 1.3 1 1 0 1 1 1 0 Propionate catabolism activator Peptidase_M10 PF00413.19 EGG42341.1 - 2.9e-11 43.3 0.0 4.1e-10 39.5 0.0 2.3 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 EGG42341.1 - 0.00053 19.3 0.1 0.00092 18.5 0.1 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.1 EGG42341.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGG42341.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EGG42341.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGG42341.1 - 0.083 12.8 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12 Peptidase_M43 PF05572.8 EGG42341.1 - 0.099 12.2 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A FtsX PF02687.16 EGG42343.1 - 0.025 14.3 0.8 0.036 13.8 0.6 1.2 1 1 0 1 1 1 0 FtsX-like permease family Cytochrom_B_N PF00033.14 EGG42343.1 - 0.09 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB SHP PF03579.8 EGG42343.1 - 8 5.9 8.7 1.3 8.3 3.5 1.5 2 0 0 2 2 2 0 Small hydrophobic protein Auto_anti-p27 PF06677.7 EGG42344.1 - 0.5 10.1 3.4 0.89 9.3 2.4 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TrmB PF01978.14 EGG42346.1 - 0.00056 19.5 0.0 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB SpoOE-like PF09388.5 EGG42346.1 - 0.015 14.7 1.0 0.035 13.6 0.1 2.1 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Cyanate_lyase PF02560.9 EGG42346.1 - 0.12 11.9 1.3 1.4 8.5 0.0 2.9 2 1 0 3 3 3 0 Cyanate lyase C-terminal domain HTH_IclR PF09339.5 EGG42346.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HEAT_2 PF13646.1 EGG42347.1 - 3.2e-13 49.7 0.1 2.7e-06 27.5 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 EGG42347.1 - 0.0039 17.1 0.1 5.6 7.3 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat CAS_CSE1 PF03378.10 EGG42347.1 - 0.042 12.1 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus COQ9 PF08511.6 EGG42347.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 COQ9 Methyltransf_21 PF05050.7 EGG42348.1 - 1.6e-21 76.9 0.1 2.4e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EGG42348.1 - 1.3e-07 32.1 0.0 2.2e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG42348.1 - 3.1e-06 26.8 0.3 8.3e-06 25.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain V_cholerae_RfbT PF05575.6 EGG42348.1 - 2.4e-05 23.5 0.1 3.2e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_23 PF13489.1 EGG42348.1 - 0.00053 19.7 0.0 0.00082 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG42348.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EGG42348.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 EGG42348.1 - 0.069 13.1 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase YolD PF08863.5 EGG42349.1 - 0.18 11.6 0.8 8.7 6.2 0.2 2.0 1 1 1 2 2 2 0 YolD-like protein DUF2418 PF10332.4 EGG42350.1 - 0.017 15.4 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) DUF1433 PF07252.6 EGG42350.1 - 0.056 13.6 0.3 0.069 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) CbtA PF09490.5 EGG42353.1 - 1e-17 64.2 0.4 1.3e-17 63.8 0.3 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) Peptidase_M50 PF02163.17 EGG42353.1 - 0.072 12.0 0.1 0.28 10.1 0.1 2.1 1 1 0 1 1 1 0 Peptidase family M50 Sugar_tr PF00083.19 EGG42353.1 - 0.17 10.3 8.5 0.074 11.6 2.5 2.1 1 1 1 2 2 2 0 Sugar (and other) transporter Mem_trans PF03547.13 EGG42353.1 - 0.18 10.0 6.0 0.71 8.0 4.1 2.0 1 1 0 1 1 1 0 Membrane transport protein CbtB PF09489.5 EGG42354.1 - 2.7e-06 27.1 10.6 0.00011 22.0 7.4 2.1 1 1 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) SecE PF00584.15 EGG42354.1 - 0.12 11.9 1.3 0.15 11.6 0.9 1.2 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4443 PF14544.1 EGG42355.1 - 1e-05 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) HTH_45 PF14947.1 EGG42355.1 - 0.0034 17.1 0.2 0.01 15.6 0.1 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix Thioredoxin_4 PF13462.1 EGG42356.1 - 1.7e-34 119.2 0.1 2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EGG42356.1 - 5.1e-16 58.8 0.0 5.2e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EGG42356.1 - 2.1e-08 34.3 0.2 5.4e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 EGG42356.1 - 3.6e-05 23.3 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HIT PF01230.18 EGG42357.1 - 1.7e-23 82.9 1.6 2.3e-23 82.5 1.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGG42357.1 - 8.1e-12 45.4 0.5 9.9e-12 45.1 0.3 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SMC_hinge PF06470.8 EGG42357.1 - 0.051 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain CwfJ_C_1 PF04677.10 EGG42357.1 - 0.1 12.2 0.8 0.16 11.6 0.6 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 P3A PF08727.6 EGG42358.1 - 0.043 13.1 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Poliovirus 3A protein like DUF2749 PF10907.3 EGG42358.1 - 0.11 12.3 0.4 8.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Lar_restr_allev PF14354.1 EGG42359.1 - 0.0039 17.4 0.1 0.0051 17.0 0.1 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar DUF2225 PF09986.4 EGG42359.1 - 0.026 13.9 1.5 0.063 12.7 1.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TF_Zn_Ribbon PF08271.7 EGG42359.1 - 0.045 13.0 0.7 6 6.2 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ISL3 PF14690.1 EGG42359.1 - 0.053 13.5 0.1 4.7 7.3 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rubredoxin PF00301.15 EGG42359.1 - 0.074 12.9 0.3 7.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin DUF2082 PF09855.4 EGG42359.1 - 0.08 12.8 2.0 0.21 11.4 1.4 1.7 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.5 EGG42359.1 - 0.11 12.4 0.8 4.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Methyltransf_13 PF08421.6 EGG42359.1 - 0.12 11.9 0.4 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative zinc binding domain TFIIS_C PF01096.13 EGG42359.1 - 0.14 11.7 2.1 6 6.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) HypA PF01155.14 EGG42359.1 - 0.2 11.3 1.2 1.8 8.2 0.1 2.0 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 EGG42359.1 - 0.22 11.0 1.3 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 EGG42359.1 - 0.23 11.0 2.9 3 7.4 0.5 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Opy2 PF09463.5 EGG42359.1 - 0.71 10.0 3.5 1.2 9.3 0.2 2.1 2 0 0 2 2 2 0 Opy2 protein zinc_ribbon_4 PF13717.1 EGG42359.1 - 2.1 8.1 4.6 4.5 7.0 0.2 2.2 1 1 2 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG42359.1 - 2.5 7.7 4.9 4.5 6.9 0.2 2.2 1 1 2 3 3 3 0 zinc-ribbon domain ILVD_EDD PF00920.16 EGG42360.1 - 4.5e-217 721.5 5.1 5.1e-217 721.4 3.5 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1263 PF06882.7 EGG42360.1 - 0.03 13.9 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) FpoO PF10621.4 EGG42361.1 - 0.68 10.0 5.3 1.8 8.6 3.7 1.7 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF4428 PF14471.1 EGG42361.1 - 6.7 6.5 10.1 9 6.1 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) Helicase_C_2 PF13307.1 EGG42364.1 - 5.6e-23 81.7 0.1 1.4e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EGG42364.1 - 6.4e-06 25.6 0.8 1.7e-05 24.2 0.2 2.0 2 0 0 2 2 2 1 DEAD_2 DUF3247 PF11607.3 EGG42364.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) GIY-YIG PF01541.19 EGG42365.1 - 8.4e-08 32.4 0.2 1.1e-07 32.1 0.2 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain A_thal_3526 PF09713.5 EGG42366.1 - 0.25 11.4 1.1 0.34 11.0 0.7 1.5 1 1 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) DUF4355 PF14265.1 EGG42367.1 - 0.0049 16.8 3.6 0.0065 16.4 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) zf-DNA_Pol PF08996.5 EGG42370.1 - 0.0034 16.7 1.1 0.0034 16.7 0.8 1.1 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zinc_ribbon_4 PF13717.1 EGG42370.1 - 0.023 14.3 0.3 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG42370.1 - 0.023 14.2 0.2 0.44 10.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-PHD-like PF15446.1 EGG42370.1 - 0.14 11.4 1.8 0.47 9.7 0.1 1.9 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_4 PF07975.7 EGG42370.1 - 0.17 11.8 4.6 0.36 10.8 3.2 1.6 1 1 0 1 1 1 0 TFIIH C1-like domain zf-AN1 PF01428.11 EGG42370.1 - 0.53 10.2 7.4 1.7 8.6 1.5 2.4 2 1 0 2 2 2 0 AN1-like Zinc finger PHD_2 PF13831.1 EGG42370.1 - 0.67 9.3 4.0 1.1 8.6 0.3 2.3 2 0 0 2 2 2 0 PHD-finger HNH PF01844.18 EGG42370.1 - 4.4 7.2 6.6 1.2 9.0 0.9 2.2 2 0 0 2 2 2 0 HNH endonuclease zf-RING_4 PF14570.1 EGG42371.1 - 0.03 13.8 6.0 0.22 11.1 1.5 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 EGG42371.1 - 0.031 14.0 10.2 0.3 10.9 5.4 2.0 1 1 1 2 2 2 0 zinc-ribbons zf-C3HC4_3 PF13920.1 EGG42371.1 - 0.061 13.0 4.9 1.3 8.7 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YdjO PF14169.1 EGG42371.1 - 0.089 12.2 7.7 0.11 12.0 1.1 2.2 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-ribbon_3 PF13248.1 EGG42371.1 - 0.091 11.9 2.1 0.32 10.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGG42371.1 - 0.16 11.5 5.8 0.24 10.9 1.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.1 EGG42371.1 - 0.18 11.8 1.1 0.18 11.8 0.7 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_5 PF13719.1 EGG42371.1 - 0.19 11.3 2.6 1.3 8.7 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG42371.1 - 0.21 11.2 2.6 1.3 8.7 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGG42371.1 - 0.39 10.4 6.9 0.27 10.9 0.5 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 EGG42371.1 - 0.39 10.4 6.0 0.51 10.0 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-IS66 PF13005.2 EGG42371.1 - 0.42 10.6 3.5 5.7 6.9 0.1 2.9 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DUF329 PF03884.9 EGG42371.1 - 0.45 10.0 6.5 5.9 6.5 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Herpes_UL31 PF02718.9 EGG42371.1 - 0.62 8.7 5.4 0.12 11.0 1.0 1.7 1 1 1 2 2 2 0 Herpesvirus UL31-like protein Sgf11 PF08209.6 EGG42371.1 - 0.73 9.1 0.1 0.73 9.1 0.1 2.7 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Spt4 PF06093.8 EGG42371.1 - 0.8 9.6 8.6 1.3 9.0 2.7 2.1 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger DZR PF12773.2 EGG42371.1 - 1 9.2 7.8 2.8 7.8 5.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 EGG42371.1 - 1.9 8.4 9.2 1.4 8.8 1.9 2.1 1 1 1 2 2 2 0 IBR domain Zn_Tnp_IS1595 PF12760.2 EGG42371.1 - 2 8.2 5.3 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-TFIIB PF13453.1 EGG42371.1 - 6 6.1 11.3 5 6.4 0.7 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-FCS PF06467.9 EGG42371.1 - 6.5 6.4 7.1 1.3 8.6 0.6 2.3 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Rad50_zn_hook PF04423.9 EGG42371.1 - 7.7 6.0 9.8 5.3 6.6 0.9 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-CXXC PF02008.15 EGG42371.1 - 8.8 6.2 10.1 2.4 8.0 0.7 2.1 2 0 0 2 2 2 0 CXXC zinc finger domain PARP_regulatory PF01358.13 EGG42372.1 - 0.0038 15.9 0.1 0.008 14.8 0.0 1.4 1 1 0 1 1 1 1 Poly A polymerase regulatory subunit DUF308 PF03729.8 EGG42379.1 - 0.0081 16.1 0.2 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) DUF872 PF05915.7 EGG42379.1 - 0.0091 15.8 3.1 0.029 14.2 2.0 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) 7TMR-DISM_7TM PF07695.6 EGG42379.1 - 0.011 15.3 0.7 0.011 15.3 0.5 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling MFS_1 PF07690.11 EGG42379.1 - 0.022 13.4 0.2 0.023 13.4 0.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3185 PF11381.3 EGG42379.1 - 0.041 13.6 0.7 2.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF1129 PF06570.6 EGG42379.1 - 0.042 13.1 1.6 0.048 12.9 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PIRT PF15099.1 EGG42379.1 - 0.057 12.6 0.3 0.069 12.3 0.2 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family NfeD PF01957.13 EGG42379.1 - 0.072 13.2 0.1 0.079 13.0 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding 2TM PF13239.1 EGG42379.1 - 0.097 12.7 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 2TM domain YtpI PF14007.1 EGG42379.1 - 0.3 11.0 4.3 0.4 10.6 0.8 2.0 1 1 1 2 2 2 0 YtpI-like protein SdpI PF13630.1 EGG42379.1 - 1.2 8.8 4.3 1.9 8.2 2.9 1.4 1 1 0 1 1 1 0 SdpI/YhfL protein family TF_Zn_Ribbon PF08271.7 EGG42380.1 - 0.015 14.5 3.4 0.2 11.0 2.3 2.2 1 1 0 1 1 1 0 TFIIB zinc-binding zf-H2C2_2 PF13465.1 EGG42380.1 - 0.028 14.7 2.1 2.6 8.4 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_4 PF13717.1 EGG42380.1 - 0.044 13.4 1.4 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG42380.1 - 0.048 13.2 1.9 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.4 EGG42380.1 - 0.054 13.3 0.9 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain PHD PF00628.24 EGG42380.1 - 0.062 12.9 0.7 6.5 6.5 0.0 2.2 2 0 0 2 2 2 0 PHD-finger RIG-I_C-RD PF11648.3 EGG42380.1 - 0.071 12.9 0.5 7 6.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I A2L_zn_ribbon PF08792.5 EGG42380.1 - 0.12 11.8 3.3 0.63 9.5 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Rpr2 PF04032.11 EGG42380.1 - 0.29 11.0 2.7 0.6 10.0 1.9 1.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nitroreductase PF00881.19 EGG42381.1 - 3.5e-30 104.9 0.0 4.9e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF1157 PF06636.6 EGG42381.1 - 0.052 12.1 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) DNA_RNApol_7kD PF03604.8 EGG42382.1 - 0.073 12.5 2.4 3 7.3 0.3 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF329 PF03884.9 EGG42382.1 - 0.12 11.8 0.6 5.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) DUF866 PF05907.8 EGG42382.1 - 0.16 11.4 2.4 0.17 11.3 1.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) RecR PF02132.10 EGG42382.1 - 0.26 10.7 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 RecR protein Ribosomal_L44 PF00935.14 EGG42382.1 - 8.6 6.4 8.8 0.42 10.6 1.7 1.9 1 1 1 2 2 2 0 Ribosomal protein L44 PAC2 PF09754.4 EGG42383.1 - 1.6e-21 77.1 0.0 2e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 PAC2 family PDDEXK_1 PF12705.2 EGG42384.1 - 1.9e-08 33.9 0.1 1.2e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.3 EGG42384.1 - 0.039 13.0 0.1 4.4 6.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2800) Cas_Cas4 PF01930.12 EGG42384.1 - 0.048 13.5 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 Hint PF01079.15 EGG42385.1 - 0.035 13.3 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Hint module Aldo_ket_red PF00248.16 EGG42387.1 - 1.2e-54 185.0 0.0 1.4e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF866 PF05907.8 EGG42388.1 - 0.045 13.2 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.7 EGG42388.1 - 0.12 11.7 3.5 1.1 8.5 2.4 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_6 PF14599.1 EGG42388.1 - 0.64 9.8 4.6 1 9.2 0.1 2.1 1 1 1 2 2 2 0 Zinc-ribbon PMT_2 PF13231.1 EGG42389.1 - 3.4e-09 36.7 18.9 3.4e-09 36.7 13.1 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glycos_transf_2 PF00535.21 EGG42390.1 - 2e-32 112.1 0.1 8.9e-32 110.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 GtrA PF04138.9 EGG42390.1 - 9e-24 83.6 11.6 3.4e-22 78.5 8.7 2.3 1 1 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.1 EGG42390.1 - 7.4e-10 39.0 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGG42390.1 - 0.00029 19.9 0.4 0.00058 19.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGG42390.1 - 0.0012 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 NTP_transf_3 PF12804.2 EGG42390.1 - 0.0099 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_5 PF13712.1 EGG42390.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family RecR PF02132.10 EGG42392.1 - 0.031 13.7 2.6 0.037 13.4 1.8 1.2 1 0 0 1 1 1 0 RecR protein P12 PF12669.2 EGG42392.1 - 0.11 12.7 6.0 0.15 12.2 4.2 1.3 1 1 0 1 1 1 0 Virus attachment protein p12 family NB PF04159.8 EGG42392.1 - 1.7 8.4 6.7 2 8.1 4.6 1.0 1 0 0 1 1 1 0 NB glycoprotein Chorismate_bind PF00425.13 EGG42394.1 - 9.4e-91 303.6 0.0 4.6e-90 301.4 0.0 1.9 2 1 1 3 3 3 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EGG42394.1 - 3.7e-22 78.8 0.0 1.8e-20 73.4 0.0 2.8 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region GATase PF00117.23 EGG42395.1 - 1.5e-55 187.6 0.0 1.6e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG42395.1 - 1.5e-09 37.6 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Glycos_transf_3 PF00591.16 EGG42396.1 - 4e-79 265.6 1.2 5.7e-79 265.0 0.9 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EGG42396.1 - 3.6e-12 45.6 0.1 7.2e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain IGPS PF00218.16 EGG42397.1 - 7.6e-72 241.4 0.8 9.1e-72 241.1 0.5 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.14 EGG42397.1 - 2.2e-06 27.2 0.0 4.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EGG42397.1 - 0.0002 20.3 0.1 0.00052 19.0 0.1 1.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF556 PF04476.8 EGG42397.1 - 0.0027 16.9 0.1 0.0092 15.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF556) FMN_dh PF01070.13 EGG42397.1 - 0.0029 16.5 0.0 0.011 14.6 0.0 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 EGG42397.1 - 0.0037 16.5 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.16 EGG42397.1 - 0.0089 15.3 0.0 0.03 13.5 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein Cellulase PF00150.13 EGG42397.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 EGG42397.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_hydro_97 PF10566.4 EGG42397.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 DHO_dh PF01180.16 EGG42397.1 - 0.042 12.7 0.9 1.7 7.4 0.0 2.5 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase EAL PF00563.15 EGG42397.1 - 0.05 13.0 0.1 4.8 6.5 0.0 2.5 2 1 1 3 3 3 0 EAL domain PALP PF00291.20 EGG42398.1 - 1.5e-42 145.8 1.4 1.9e-42 145.5 1.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.15 EGG42399.1 - 1.3e-84 282.7 2.5 1.5e-84 282.6 1.7 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.16 EGG42399.1 - 3e-08 33.2 0.2 1.3e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.12 EGG42399.1 - 7.2e-08 31.9 0.6 1e-06 28.1 0.2 2.3 2 0 0 2 2 2 1 PcrB family DHO_dh PF01180.16 EGG42399.1 - 1.9e-07 30.3 0.8 2.7e-07 29.8 0.6 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EGG42399.1 - 2.2e-05 23.4 0.1 9.4e-05 21.4 0.0 2.0 1 1 1 3 3 3 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGG42399.1 - 2.7e-05 23.2 0.6 0.00031 19.7 0.1 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 EGG42399.1 - 2.7e-05 23.2 0.5 0.00039 19.4 0.1 2.7 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 EGG42399.1 - 0.00095 18.3 0.2 0.002 17.2 0.0 1.7 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG BtpA PF03437.10 EGG42399.1 - 0.0022 17.2 1.3 0.017 14.4 0.9 2.4 1 1 0 1 1 1 1 BtpA family IGPS PF00218.16 EGG42399.1 - 0.0039 16.2 0.0 0.017 14.2 0.0 2.0 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 EGG42399.1 - 0.012 14.7 0.7 0.032 13.3 0.5 2.0 1 1 0 1 1 1 0 Thiamine monophosphate synthase/TENI Ribul_P_3_epim PF00834.14 EGG42399.1 - 0.032 13.3 0.2 0.052 12.6 0.1 1.5 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family NMO PF03060.10 EGG42399.1 - 0.042 12.9 0.0 0.095 11.8 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase QRPTase_C PF01729.14 EGG42399.1 - 0.056 12.9 0.1 7.9 5.9 0.0 2.5 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain TGT PF01702.13 EGG42399.1 - 0.059 12.6 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase GDPD PF03009.12 EGG42399.1 - 0.074 12.5 0.0 0.4 10.1 0.0 1.9 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Radical_SAM PF04055.16 EGG42399.1 - 0.16 12.0 0.5 0.74 9.9 0.4 2.1 1 1 0 1 1 1 0 Radical SAM superfamily zf-C2H2_4 PF13894.1 EGG42400.1 - 0.00084 19.5 13.2 0.098 13.0 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Prok-RING_1 PF14446.1 EGG42400.1 - 0.0026 17.4 3.0 1 9.1 0.1 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 EGG42400.1 - 0.0045 16.9 1.4 0.032 14.2 0.1 2.2 2 0 0 2 2 2 1 zinc-finger zf-C2H2 PF00096.21 EGG42400.1 - 0.014 15.6 13.5 0.34 11.3 2.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGG42400.1 - 0.018 15.1 4.5 0.018 15.1 3.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EGG42400.1 - 0.027 14.7 5.8 0.027 14.7 4.0 2.8 3 1 0 3 3 2 0 Zinc-finger double domain DZR PF12773.2 EGG42400.1 - 0.056 13.2 2.7 0.12 12.2 1.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 EGG42400.1 - 0.062 12.9 5.4 1.1 8.9 3.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-CHCC PF10276.4 EGG42400.1 - 0.079 12.8 0.9 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger domain zinc_ribbon_4 PF13717.1 EGG42400.1 - 0.08 12.6 5.2 1.4 8.6 3.6 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-CSL PF05207.8 EGG42400.1 - 0.08 12.4 0.3 0.14 11.6 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger zf-C2H2_jaz PF12171.3 EGG42400.1 - 0.1 12.7 15.5 0.45 10.7 2.3 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGG42400.1 - 0.18 11.7 6.0 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger YhfH PF14149.1 EGG42400.1 - 0.19 11.5 0.3 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 YhfH-like protein DNA_RNApol_7kD PF03604.8 EGG42400.1 - 0.2 11.1 2.7 0.93 9.0 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.12 EGG42400.1 - 0.23 11.0 3.7 0.58 9.7 2.6 1.7 1 1 0 1 1 1 0 Ribosomal protein S27 GCC2_GCC3 PF07699.8 EGG42400.1 - 0.25 10.9 1.6 9.9 5.8 0.1 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 Mut7-C PF01927.11 EGG42400.1 - 0.3 11.0 3.6 0.28 11.1 2.0 1.4 1 1 0 1 1 1 0 Mut7-C RNAse domain LIM PF00412.17 EGG42400.1 - 0.57 10.2 9.1 0.82 9.7 6.3 1.3 1 0 0 1 1 1 0 LIM domain zf-trcl PF13451.1 EGG42400.1 - 0.65 9.6 3.5 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain FYDLN_acid PF09538.5 EGG42400.1 - 0.77 10.3 4.6 5.5 7.6 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-FCS PF06467.9 EGG42400.1 - 0.84 9.3 5.3 4.4 7.0 0.7 2.2 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.10 EGG42400.1 - 1 9.1 9.2 0.4 10.4 3.2 2.2 1 1 1 2 2 2 0 BED zinc finger Terminase_GpA PF05876.7 EGG42400.1 - 1.2 7.4 5.6 1.3 7.3 3.9 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-HYPF PF07503.7 EGG42400.1 - 1.5 8.3 4.9 0.57 9.6 0.8 2.1 2 0 0 2 2 2 0 HypF finger zinc_ribbon_2 PF13240.1 EGG42400.1 - 1.7 8.2 4.9 13 5.4 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain DUF629 PF04780.7 EGG42400.1 - 1.8 6.9 15.3 6.8 5.0 8.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-LYAR PF08790.6 EGG42400.1 - 3.3 7.4 7.3 0.62 9.8 0.9 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger FYVE PF01363.16 EGG42400.1 - 3.9 7.4 11.2 46 3.9 7.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-Di19 PF05605.7 EGG42400.1 - 9.1 6.4 17.5 7.7 6.7 3.7 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CTP_synth_N PF06418.9 EGG42401.1 - 3.7e-115 383.7 0.1 5e-115 383.3 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGG42401.1 - 2.3e-50 170.7 0.0 3.9e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG42401.1 - 1.4e-13 50.7 0.0 1.9e-12 47.0 0.0 2.2 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.18 EGG42401.1 - 1.4e-06 27.9 0.0 4.3e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain NAD_kinase PF01513.16 EGG42402.1 - 2.8e-32 111.6 0.3 3.8e-32 111.2 0.2 1.1 1 0 0 1 1 1 1 ATP-NAD kinase TrmB PF01978.14 EGG42402.1 - 2.7e-05 23.7 1.5 0.001 18.7 0.2 2.8 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 EGG42402.1 - 4e-05 23.2 1.9 6.4e-05 22.5 0.1 2.2 3 0 0 3 3 3 1 MarR family RNA_pol_Rpc34 PF05158.7 EGG42402.1 - 4.8e-05 22.6 1.0 6.7e-05 22.2 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_27 PF13463.1 EGG42402.1 - 0.00015 22.0 0.4 0.00033 20.9 0.3 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.2 EGG42402.1 - 0.0003 20.3 0.1 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 EGG42402.1 - 0.00037 19.8 2.4 0.00076 18.8 0.1 2.5 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding FeoC PF09012.5 EGG42402.1 - 0.038 13.6 1.2 0.15 11.8 0.0 2.3 3 0 0 3 3 3 0 FeoC like transcriptional regulator TFIIE_alpha PF02002.12 EGG42402.1 - 0.15 11.6 1.4 0.36 10.3 0.2 2.1 2 1 1 3 3 3 0 TFIIE alpha subunit PfkB PF00294.19 EGG42403.1 - 2.7e-11 43.1 0.0 1.4e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HMA PF00403.21 EGG42403.1 - 0.12 12.5 0.1 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Heavy-metal-associated domain HTH_20 PF12840.2 EGG42404.1 - 8e-07 28.7 0.0 8.6e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 EGG42404.1 - 1.5e-06 27.7 0.2 1.8e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 EGG42404.1 - 9.7e-06 24.8 1.7 1.3e-05 24.4 1.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF1492 PF07374.6 EGG42404.1 - 0.00032 20.7 0.1 0.00037 20.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) HTH_IclR PF09339.5 EGG42404.1 - 0.00033 20.1 0.0 0.00044 19.7 0.0 1.3 1 1 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.15 EGG42404.1 - 0.00035 20.1 0.4 0.00042 19.9 0.3 1.1 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.7 EGG42404.1 - 0.00089 18.8 1.3 0.0012 18.4 0.9 1.3 1 0 0 1 1 1 1 HTH domain Mga PF05043.8 EGG42404.1 - 0.0029 17.8 0.2 0.0032 17.7 0.1 1.1 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_23 PF13384.1 EGG42404.1 - 0.0076 15.8 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.2 EGG42404.1 - 0.01 15.4 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 MarR family Sigma70_r4 PF04545.11 EGG42404.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 FUR PF01475.14 EGG42404.1 - 0.019 14.8 0.1 0.022 14.6 0.0 1.2 1 1 0 1 1 1 0 Ferric uptake regulator family HTH_8 PF02954.14 EGG42404.1 - 0.021 14.3 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_27 PF13463.1 EGG42404.1 - 0.036 14.3 0.1 0.046 14.0 0.1 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 EGG42404.1 - 0.037 14.1 0.3 0.044 13.8 0.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator DUF2250 PF10007.4 EGG42404.1 - 0.1 12.5 0.3 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_7 PF02796.10 EGG42404.1 - 0.12 12.2 0.1 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TFIIE_alpha PF02002.12 EGG42404.1 - 0.12 11.8 0.5 0.13 11.8 0.4 1.0 1 0 0 1 1 1 0 TFIIE alpha subunit DUF3791 PF12668.2 EGG42404.1 - 0.13 11.8 0.3 0.4 10.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3791) MerC PF03203.9 EGG42405.1 - 0.0026 18.1 2.8 0.0053 17.1 2.0 1.5 1 1 0 1 1 1 1 MerC mercury resistance protein 7TMR-DISM_7TM PF07695.6 EGG42405.1 - 0.02 14.5 2.9 0.022 14.4 2.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF3290 PF11694.3 EGG42405.1 - 0.063 13.0 2.1 0.055 13.2 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) DUF981 PF06168.6 EGG42405.1 - 0.083 12.6 5.4 0.059 13.1 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF981) DUF2955 PF11168.3 EGG42405.1 - 0.13 11.8 2.0 0.12 12.0 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2955) OAD_beta PF03977.8 EGG42405.1 - 0.14 10.8 3.6 0.16 10.6 2.5 1.1 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit DUF2892 PF11127.3 EGG42405.1 - 0.39 10.5 2.6 0.58 10.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) SPW PF03779.9 EGG42405.1 - 0.54 9.6 4.5 0.58 9.5 0.1 2.6 3 0 0 3 3 3 0 SPW repeat DUF204 PF02659.10 EGG42405.1 - 3 8.0 7.7 5.7 7.1 2.3 2.7 1 1 1 2 2 2 0 Domain of unknown function DUF 7TMR-DISM_7TM PF07695.6 EGG42407.1 - 0.93 9.1 20.0 0.064 12.9 3.2 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling Ribosomal_S26e PF01283.14 EGG42408.1 - 7.3e-32 109.9 1.5 8e-32 109.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF3279 PF11682.3 EGG42408.1 - 0.036 13.6 2.3 0.52 9.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) zf-dskA_traR PF01258.12 EGG42408.1 - 0.36 10.6 2.2 1.8 8.3 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger CDP-OH_P_transf PF01066.16 EGG42409.1 - 9.7e-18 64.3 7.4 2.3e-17 63.1 5.2 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Class_IIIsignal PF04021.7 EGG42409.1 - 0.042 13.5 3.0 0.042 13.5 2.1 4.5 5 0 0 5 5 5 0 Class III signal peptide Arginase PF00491.16 EGG42410.1 - 2.3e-67 227.2 0.0 2.8e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family tRNA-Thr_ED PF08915.6 EGG42411.1 - 1.3e-47 161.2 0.2 2.2e-47 160.4 0.2 1.4 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGG42411.1 - 1.5e-26 93.0 0.9 3.2e-26 91.9 0.6 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGG42411.1 - 2.6e-24 84.9 0.4 6.4e-24 83.7 0.3 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF2061 PF09834.4 EGG42412.1 - 8.2e-08 32.3 6.2 9.8e-08 32.0 4.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2061) Polysacc_synt_3 PF13440.1 EGG42412.1 - 0.00086 18.8 1.1 0.00096 18.6 0.8 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CRT-like PF08627.5 EGG42412.1 - 0.11 12.4 0.3 0.12 12.3 0.2 1.1 1 0 0 1 1 1 0 CRT-like DUF4199 PF13858.1 EGG42412.1 - 0.15 11.9 2.7 0.16 11.8 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Rhodanese PF00581.15 EGG42415.1 - 1.6e-10 41.2 0.0 2.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain SDP_N PF12278.3 EGG42415.1 - 0.061 12.9 0.6 0.072 12.7 0.4 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal TrkH PF02386.11 EGG42416.1 - 9.9e-28 96.7 42.0 3.2e-26 91.7 21.9 3.3 1 1 0 2 2 2 2 Cation transport protein CBS PF00571.23 EGG42416.1 - 3.8e-15 55.3 3.8 5.1e-07 29.3 0.2 2.6 2 0 0 2 2 2 2 CBS domain zf-C2H2_2 PF12756.2 EGG42417.1 - 0.001 19.1 0.4 0.001 19.1 0.3 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGG42417.1 - 0.0065 16.7 1.7 0.0075 16.5 0.4 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF3222 PF11519.3 EGG42417.1 - 0.0077 16.1 0.0 0.0077 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3222) zf-C2H2_4 PF13894.1 EGG42417.1 - 0.018 15.3 0.2 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF629 PF04780.7 EGG42417.1 - 0.068 11.6 0.1 0.068 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_3 PF13878.1 EGG42417.1 - 0.11 12.1 0.8 0.15 11.6 0.5 1.4 1 1 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO HTH_45 PF14947.1 EGG42418.1 - 6.1e-07 29.1 0.6 6.1e-07 29.1 0.4 1.5 2 0 0 2 2 2 1 Winged helix-turn-helix MarR PF01047.17 EGG42418.1 - 1.7e-05 24.4 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.1 EGG42418.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.9 EGG42418.1 - 0.032 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF505 PF04458.7 EGG42418.1 - 0.054 11.6 0.1 0.094 10.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF505) NicO PF03824.11 EGG42419.1 - 0.014 14.7 0.2 0.017 14.4 0.2 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein YqjK PF13997.1 EGG42419.1 - 0.015 15.4 0.7 17 5.6 0.0 3.0 2 1 0 2 2 2 0 YqjK-like protein DUF4064 PF13273.1 EGG42419.1 - 0.017 15.2 0.3 0.68 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Colicin_V PF02674.11 EGG42419.1 - 0.018 14.8 2.0 0.028 14.2 1.4 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF2207 PF09972.4 EGG42419.1 - 0.025 13.1 0.1 0.025 13.1 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EutH PF04346.7 EGG42419.1 - 0.038 12.9 0.7 0.045 12.7 0.5 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH O-antigen_lig PF13425.1 EGG42419.1 - 0.052 13.5 1.4 0.065 13.2 1.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4389 PF14333.1 EGG42419.1 - 0.088 12.5 0.9 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF2976 PF11190.3 EGG42419.1 - 0.62 9.6 5.4 1.6 8.2 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) zf-LSD1 PF06943.7 EGG42420.1 - 0.019 14.5 4.3 0.39 10.3 0.6 2.3 2 0 0 2 2 2 0 LSD1 zinc finger Prok-JAB PF14464.1 EGG42422.1 - 5.2e-13 48.4 0.0 6e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 EGG42422.1 - 0.0088 15.7 0.0 0.071 12.8 0.0 1.9 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.10 EGG42422.1 - 0.012 15.2 0.1 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain Toxin-JAB1 PF15659.1 EGG42422.1 - 0.096 12.5 0.7 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 JAB-like toxin 1 Guanylate_cyc PF00211.15 EGG42423.1 - 1.1e-17 63.9 0.0 1.5e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DS PF01916.12 EGG42424.1 - 8e-57 192.6 0.1 9.3e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase THAP PF05485.7 EGG42425.1 - 0.12 12.5 1.0 1.4 9.1 0.7 2.0 1 1 0 1 1 1 0 THAP domain Ribosomal_S25 PF03297.10 EGG42426.1 - 1.3e-06 28.3 3.1 1.6e-06 28.0 2.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.14 EGG42426.1 - 0.0063 16.1 0.1 0.0085 15.7 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.6 EGG42426.1 - 0.013 15.2 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DDRGK PF09756.4 EGG42426.1 - 0.021 14.2 1.5 0.042 13.2 1.0 1.5 1 1 0 1 1 1 0 DDRGK domain MarR_2 PF12802.2 EGG42426.1 - 0.039 13.6 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_10 PF04967.7 EGG42426.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Cyclophil_like PF04126.8 EGG42427.1 - 1.2e-07 31.3 0.0 2.1e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin-like RNA_pol_Rpb6 PF01192.17 EGG42428.1 - 1.3e-12 47.2 0.1 1.3e-12 47.2 0.1 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb6 DUF3782 PF12644.2 EGG42428.1 - 0.29 10.9 1.6 0.35 10.6 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Unstab_antitox PF09720.5 EGG42428.1 - 0.41 10.3 4.5 0.29 10.8 1.0 2.4 3 0 0 3 3 3 0 Putative addiction module component Alba PF01918.16 EGG42429.1 - 3.7e-09 36.0 0.2 5e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Alba Ribosomal_L2 PF00181.18 EGG42429.1 - 0.031 14.2 0.2 0.065 13.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain Rpp20 PF12328.3 EGG42429.1 - 0.13 11.8 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P HTH_19 PF12844.2 EGG42430.1 - 3.9e-05 23.6 0.1 0.00058 19.8 0.0 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.17 EGG42430.1 - 6.1e-05 22.7 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.1 EGG42430.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_26 PF13443.1 EGG42430.1 - 0.034 14.3 0.2 0.19 11.9 0.0 2.3 2 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain HTH_11 PF08279.7 EGG42430.1 - 0.052 13.1 0.6 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 HTH domain HTH_37 PF13744.1 EGG42430.1 - 0.071 12.9 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CAS_CSE1 PF03378.10 EGG42430.1 - 0.093 11.0 0.0 0.13 10.5 0.0 1.3 1 1 0 1 1 1 0 CAS/CSE protein, C-terminus Asn_synthase PF00733.16 EGG42431.1 - 1.6e-33 116.3 0.0 8.2e-32 110.6 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGG42431.1 - 2.9e-05 23.4 0.8 0.00015 21.0 0.1 2.4 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 EGG42431.1 - 3.5e-05 22.8 0.6 5.5e-05 22.1 0.1 1.5 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.15 EGG42431.1 - 0.00021 20.8 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.9 EGG42431.1 - 0.00065 19.2 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) zf-ribbon_3 PF13248.1 EGG42431.1 - 0.0021 17.2 2.2 0.0021 17.2 1.5 1.9 2 0 0 2 2 2 1 zinc-ribbon domain tRNA_Me_trans PF03054.11 EGG42431.1 - 0.0024 16.5 0.0 0.0069 14.9 0.0 1.8 2 1 0 2 2 2 1 tRNA methyl transferase zinc_ribbon_2 PF13240.1 EGG42431.1 - 0.055 12.9 3.9 8.9 5.9 0.3 2.6 1 1 1 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGG42431.1 - 0.17 11.7 3.6 0.22 11.3 0.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon RecR PF02132.10 EGG42431.1 - 4.3 6.8 8.2 0.19 11.1 1.2 2.2 2 1 0 2 2 2 0 RecR protein Aldo_ket_red PF00248.16 EGG42433.1 - 4.1e-32 111.1 0.0 1.3e-31 109.4 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF321 PF03778.8 EGG42433.1 - 0.24 10.8 3.2 0.18 11.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF321) UbiA PF01040.13 EGG42434.1 - 1.3e-27 96.6 21.3 1.7e-27 96.2 14.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3488 PF11992.3 EGG42434.1 - 0.053 12.1 0.8 0.08 11.5 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3488) Phage_holin_2 PF04550.7 EGG42434.1 - 2 8.5 9.6 0.28 11.3 0.1 3.1 3 0 0 3 3 3 0 Phage holin family 2 Rhabdo_glycop PF00974.13 EGG42435.1 - 0.034 12.3 0.1 0.064 11.4 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Spore_YhaL PF14147.1 EGG42435.1 - 0.19 11.2 1.0 0.37 10.2 0.7 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL DUF1628 PF07790.6 EGG42436.1 - 0.00088 19.9 1.6 0.00088 19.9 1.1 2.3 2 2 1 3 3 3 1 Protein of unknown function (DUF1628) DUF3899 PF13038.1 EGG42436.1 - 0.5 10.5 2.4 0.87 9.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) NPCBM_assoc PF10633.4 EGG42437.1 - 0.0006 19.8 5.6 0.092 12.8 0.4 4.5 5 0 0 5 5 5 2 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF1628 PF07790.6 EGG42438.1 - 0.075 13.7 4.4 0.069 13.9 1.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1628) Zn-ribbon_8 PF09723.5 EGG42440.1 - 0.0014 18.5 9.9 0.75 9.7 0.7 4.3 4 0 0 4 4 4 2 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EGG42440.1 - 0.055 13.0 11.2 0.99 9.0 2.1 3.8 3 0 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 EGG42440.1 - 0.07 13.1 5.5 0.12 12.4 1.0 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain YdjO PF14169.1 EGG42440.1 - 0.087 12.2 4.2 1.2 8.6 0.3 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO HypA PF01155.14 EGG42440.1 - 0.22 11.2 6.3 13 5.5 0.1 3.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 EGG42440.1 - 0.31 10.7 11.0 5.7 6.7 2.0 3.9 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EGG42440.1 - 0.43 10.3 4.8 5 6.9 0.0 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Terminase_GpA PF05876.7 EGG42440.1 - 0.51 8.6 2.6 0.83 7.9 1.8 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) FYVE PF01363.16 EGG42440.1 - 0.65 9.9 8.7 0.91 9.4 0.2 2.4 2 0 0 2 2 2 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 EGG42440.1 - 0.76 9.6 6.0 0.97 9.2 0.7 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.7 EGG42440.1 - 3.4 7.5 10.4 2.2 8.1 2.6 2.6 1 1 2 3 3 3 0 zinc-ribbons zf-C3HC4_3 PF13920.1 EGG42440.1 - 4 7.1 10.2 6.6 6.4 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) T2SE PF00437.15 EGG42441.1 - 6.6e-50 169.5 0.0 1.2e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EGG42441.1 - 0.00039 19.8 0.0 0.00086 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGG42441.1 - 0.00058 20.6 0.4 0.0038 18.0 0.0 2.6 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGG42441.1 - 0.00062 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EGG42441.1 - 0.0079 16.5 2.1 0.018 15.3 0.0 2.6 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EGG42441.1 - 0.012 15.9 0.2 0.11 12.8 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EGG42441.1 - 0.032 14.0 0.1 0.07 12.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EGG42441.1 - 0.041 12.9 0.0 0.088 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 EGG42441.1 - 0.098 12.2 0.2 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain T2SF PF00482.18 EGG42442.1 - 5.3e-15 55.4 0.2 5.3e-15 55.4 0.1 2.8 4 0 0 4 4 4 1 Type II secretion system (T2SS), protein F T2SF PF00482.18 EGG42443.1 - 2.8e-15 56.3 0.3 2.8e-15 56.3 0.2 2.3 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F DUF3671 PF12420.3 EGG42443.1 - 0.00027 20.8 8.7 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function MtrG PF04210.8 EGG42443.1 - 0.0065 16.1 0.6 0.056 13.1 0.3 2.5 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, subunit G TrmB PF01978.14 EGG42444.1 - 3.6e-14 52.1 0.1 8.1e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 EGG42444.1 - 9.6e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 EGG42444.1 - 0.00018 21.2 0.0 0.00043 20.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 EGG42444.1 - 0.0017 18.0 0.0 0.0045 16.6 0.0 1.7 1 0 0 1 1 1 1 MarR family Regulator_TrmB PF11495.3 EGG42444.1 - 0.013 14.5 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB HTH_24 PF13412.1 EGG42444.1 - 0.05 13.0 0.1 0.099 12.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 EGG42444.1 - 0.069 12.8 0.7 0.31 10.7 0.1 2.3 2 0 0 2 2 2 0 HTH domain HTH_27 PF13463.1 EGG42444.1 - 0.099 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_34 PF13601.1 EGG42444.1 - 0.13 12.2 0.9 0.71 9.9 0.0 2.6 4 0 0 4 4 4 0 Winged helix DNA-binding domain DUF2203 PF09969.4 EGG42445.1 - 9.5e-37 125.8 0.2 1.1e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) CENP-K PF11802.3 EGG42445.1 - 0.029 13.6 0.2 0.034 13.3 0.1 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DUF4450 PF14614.1 EGG42445.1 - 0.037 13.1 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Bet_v_1 PF00407.14 EGG42445.1 - 0.072 12.7 0.1 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Pathogenesis-related protein Bet v I family DUF2407_C PF13373.1 EGG42446.1 - 0.073 12.9 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain Pyridox_oxidase PF01243.15 EGG42447.1 - 1.3e-12 47.5 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EGG42447.1 - 6.7e-07 29.2 0.0 8.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.7 EGG42447.1 - 0.09 12.3 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Rotamase_3 PF13616.1 EGG42448.1 - 6.6e-27 94.1 0.1 7.7e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EGG42448.1 - 1.2e-25 90.0 0.1 1.4e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EGG42448.1 - 1.4e-09 38.6 0.0 1.7e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain NTPase_I-T PF01931.13 EGG42448.1 - 0.082 12.6 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 PapD_C PF02753.12 EGG42448.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain S100PBPR PF15427.1 EGG42449.1 - 0.11 11.5 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 S100P-binding protein PWI PF01480.12 EGG42449.1 - 0.11 12.6 0.7 0.15 12.1 0.4 1.3 1 1 0 1 1 1 0 PWI domain Helicase_C PF00271.26 EGG42450.1 - 8.9e-21 73.5 0.3 3.5e-20 71.6 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG42450.1 - 9.3e-20 70.7 0.1 1.3e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG42450.1 - 1.3e-17 64.2 0.0 3.4e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGG42450.1 - 0.00053 18.8 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EGG42450.1 - 0.001 19.0 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_19 PF13245.1 EGG42450.1 - 0.0016 18.1 0.0 0.0057 16.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Flavi_DEAD PF07652.9 EGG42450.1 - 0.0028 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2007 PF09413.5 EGG42450.1 - 0.12 12.2 0.1 0.78 9.6 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2007) TrmB PF01978.14 EGG42451.1 - 3.6e-15 55.4 0.0 2.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 EGG42451.1 - 5e-05 22.8 0.0 9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.17 EGG42451.1 - 0.00031 20.3 0.0 0.0012 18.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.7 EGG42451.1 - 0.00096 18.7 0.0 0.0029 17.2 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.1 EGG42451.1 - 0.001 18.3 0.0 0.0021 17.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.14 EGG42451.1 - 0.0024 17.7 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Regulator_TrmB PF11495.3 EGG42451.1 - 0.0084 15.1 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB Ftsk_gamma PF09397.5 EGG42451.1 - 0.02 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain HTH_IclR PF09339.5 EGG42451.1 - 0.039 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Pedibin PF08182.6 EGG42451.1 - 0.086 12.3 1.5 0.16 11.4 1.1 1.4 1 0 0 1 1 1 0 Pedibin/Hym-346 family HTH_20 PF12840.2 EGG42451.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.11 EGG42452.1 - 3.3e-27 95.1 66.2 4.8e-21 74.8 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGG42452.1 - 0.077 11.0 5.2 0.82 7.7 0.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector A2M_N PF01835.14 EGG42453.1 - 2.8e-05 24.2 0.2 0.067 13.4 0.0 2.2 2 0 0 2 2 2 2 MG2 domain FlgD_ig PF13860.1 EGG42453.1 - 4e-05 23.2 1.4 0.017 14.8 0.1 2.6 2 1 0 2 2 2 2 FlgD Ig-like domain PsbH PF00737.15 EGG42453.1 - 0.0048 16.4 0.3 0.012 15.1 0.2 1.6 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein VIT1 PF01988.14 EGG42454.1 - 4.4e-55 186.4 2.8 5.4e-55 186.1 1.9 1.0 1 0 0 1 1 1 1 VIT family DUF1049 PF06305.6 EGG42454.1 - 0.014 14.8 2.9 3.2 7.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) Carbpep_Y_N PF05388.6 EGG42454.1 - 0.041 14.0 0.1 0.077 13.1 0.0 1.5 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide TM_helix PF05552.7 EGG42455.1 - 2.1e-11 43.2 4.7 3.8e-05 23.2 0.2 2.9 2 0 0 2 2 2 2 Conserved TM helix MS_channel PF00924.13 EGG42455.1 - 4.1e-07 29.5 7.9 4.1e-07 29.5 5.5 3.0 3 1 0 3 3 3 1 Mechanosensitive ion channel DUF502 PF04367.8 EGG42455.1 - 0.099 12.4 3.6 6.4 6.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF502) DUF1043 PF06295.7 EGG42455.1 - 0.38 10.3 2.2 4.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) NPCC PF08058.6 EGG42455.1 - 0.48 10.2 10.8 1.5 8.6 1.1 2.5 2 1 0 2 2 2 0 Nuclear pore complex component FA_desaturase PF00487.19 EGG42455.1 - 3 7.2 7.6 1.9 7.8 3.7 1.8 1 1 0 1 1 1 0 Fatty acid desaturase MIF4G_like_2 PF09090.6 EGG42456.1 - 0.015 14.4 0.3 0.015 14.4 0.2 1.4 2 0 0 2 2 2 0 MIF4G like RimK PF08443.6 EGG42456.1 - 0.059 12.8 1.4 0.13 11.7 0.2 1.9 1 1 0 2 2 2 0 RimK-like ATP-grasp domain Tubulin PF00091.20 EGG42457.1 - 2.2e-18 66.8 0.0 4.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Snf7 PF03357.16 EGG42458.1 - 2.2e-07 30.4 0.0 2.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Snf7 DASH_Dam1 PF08653.5 EGG42458.1 - 0.00032 20.3 0.1 2.6 7.8 0.1 3.5 2 1 2 4 4 4 2 DASH complex subunit Dam1 Baculo_PEP_C PF04513.7 EGG42458.1 - 0.051 13.3 0.6 1 9.2 0.0 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus dCMP_cyt_deam_1 PF00383.17 EGG42459.1 - 1.8e-25 88.4 1.3 2.5e-25 88.0 0.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DNA_pol_B PF00136.16 EGG42460.1 - 4.8e-84 282.7 6.7 7.2e-84 282.2 4.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGG42460.1 - 7.2e-43 146.6 3.1 1.3e-42 145.8 2.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 EGG42460.1 - 3.4e-07 30.2 1.9 1.1e-06 28.5 1.4 1.8 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EGG42460.1 - 7.1e-06 25.7 1.9 3e-05 23.6 1.3 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB MtN3_slv PF03083.11 EGG42461.1 - 3.5e-08 33.1 3.3 3.9e-08 33.0 2.3 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 EGG42461.1 - 7e-05 22.2 4.2 7e-05 22.2 2.9 1.5 2 0 0 2 2 2 1 PQ loop repeat DUF4389 PF14333.1 EGG42461.1 - 0.018 14.7 2.5 0.52 10.0 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) 7TM-7TMR_HD PF07698.6 EGG42461.1 - 0.081 12.3 4.5 0.1 12.0 3.1 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF3784 PF12650.2 EGG42461.1 - 0.1 12.5 12.8 3 7.8 8.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) Syndecan PF01034.15 EGG42461.1 - 0.54 9.9 3.1 1.1 8.9 2.2 1.7 1 1 0 1 1 1 0 Syndecan domain VirB3 PF05101.8 EGG42461.1 - 0.93 9.5 7.2 0.71 9.8 1.7 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF3487 PF11990.3 EGG42461.1 - 0.98 8.8 4.6 1.4 8.3 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) TIM PF00121.13 EGG42462.1 - 1.3e-28 99.7 6.3 2.9e-26 92.0 4.3 2.0 1 1 0 1 1 1 1 Triosephosphate isomerase ThiG PF05690.9 EGG42462.1 - 1.4e-05 24.3 0.2 2.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.13 EGG42462.1 - 0.00035 19.5 0.0 0.00057 18.8 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IGPS PF00218.16 EGG42462.1 - 0.0027 16.8 0.1 0.0055 15.7 0.1 1.6 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase PcrB PF01884.12 EGG42462.1 - 0.19 10.9 6.0 0.15 11.3 0.6 2.5 1 1 0 2 2 2 0 PcrB family zf-CDGSH PF09360.5 EGG42464.1 - 4e-13 48.9 1.3 4.9e-13 48.6 0.9 1.1 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Glyoxalase_2 PF12681.2 EGG42465.1 - 8.2e-13 48.9 0.0 1.3e-12 48.2 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGG42465.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PEP-utilizers_C PF02896.13 EGG42466.1 - 1.9e-89 299.4 0.5 3.3e-89 298.6 0.4 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 EGG42466.1 - 1.5e-61 208.2 0.0 9.4e-61 205.6 0.0 2.2 2 1 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 EGG42466.1 - 2.1e-23 81.6 0.3 6.5e-23 80.0 0.2 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain CBS PF00571.23 EGG42467.1 - 5.8e-15 54.8 0.1 5.1e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 CBS domain HTH_3 PF01381.17 EGG42467.1 - 6.4e-12 45.1 0.1 1.2e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EGG42467.1 - 2.9e-08 33.6 0.1 5.8e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EGG42467.1 - 1.7e-06 28.1 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 EGG42467.1 - 0.02 15.0 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.11 EGG42467.1 - 0.1 11.9 0.1 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_25 PF13413.1 EGG42467.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3154 PF11351.3 EGG42468.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Glyoxalase_4 PF13669.1 EGG42469.1 - 4.1e-22 78.2 0.0 4.8e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 EGG42469.1 - 7.9e-12 45.2 0.0 8.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGG42469.1 - 2.1e-11 44.0 0.0 2.3e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.2 EGG42469.1 - 6.9e-07 29.8 0.0 8.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Hemerythrin PF01814.18 EGG42470.1 - 1.5e-12 47.7 0.7 2.4e-12 47.1 0.1 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF1053 PF06327.9 EGG42470.1 - 0.042 14.1 0.4 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) MM_CoA_mutase PF01642.17 EGG42471.1 - 3.1e-185 616.2 0.1 3.5e-185 616.0 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase PAP_PilO PF06864.7 EGG42471.1 - 0.0067 14.8 0.0 0.021 13.2 0.0 1.7 2 0 0 2 2 2 1 Pilin accessory protein (PilO) ArgK PF03308.11 EGG42472.1 - 1.3e-70 237.2 3.3 1.6e-70 236.9 2.3 1.1 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 EGG42472.1 - 1e-06 28.3 0.2 3e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EGG42472.1 - 1.1e-05 25.1 0.9 0.0074 15.8 0.1 2.6 2 1 1 3 3 3 2 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 EGG42472.1 - 8e-05 21.7 0.0 0.00018 20.5 0.0 1.7 1 1 0 1 1 1 1 KAP family P-loop domain AAA_10 PF12846.2 EGG42472.1 - 0.0013 18.2 0.1 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 EGG42472.1 - 0.0023 17.1 0.4 0.01 15.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGG42472.1 - 0.0048 16.9 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EGG42472.1 - 0.0055 16.4 0.5 0.11 12.1 0.1 2.8 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EGG42472.1 - 0.0097 14.7 1.5 0.04 12.7 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 EGG42472.1 - 0.011 16.0 1.3 0.034 14.4 0.1 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EGG42472.1 - 0.014 15.5 0.7 2.1 8.5 0.0 3.3 3 1 0 3 3 3 0 RNA helicase AAA_22 PF13401.1 EGG42472.1 - 0.017 15.2 0.3 0.15 12.2 0.1 2.5 1 1 2 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EGG42472.1 - 0.019 14.0 0.4 0.067 12.2 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EGG42472.1 - 0.025 14.3 3.7 0.046 13.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 EGG42472.1 - 0.036 13.7 0.5 0.11 12.2 0.2 2.0 2 0 0 2 2 1 0 NTPase PRK PF00485.13 EGG42472.1 - 0.043 13.3 2.4 0.053 13.0 0.1 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EGG42472.1 - 0.045 14.5 2.3 0.054 14.3 0.2 2.2 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EGG42472.1 - 0.047 13.2 0.3 0.099 12.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGG42472.1 - 0.051 12.7 0.8 0.72 9.0 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein Peptidase_C93 PF06035.6 EGG42472.1 - 0.053 12.9 0.2 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP AAA_29 PF13555.1 EGG42472.1 - 0.085 12.4 0.4 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGG42472.1 - 0.086 13.1 12.9 1 9.6 8.8 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGG42472.1 - 0.095 12.6 4.3 0.52 10.2 3.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase SVM_signal PF12113.3 EGG42473.1 - 0.11 12.3 1.0 0.2 11.5 0.7 1.4 1 0 0 1 1 1 0 SVM protein signal sequence Internalin_N PF12354.3 EGG42473.1 - 0.13 11.9 0.5 0.22 11.1 0.4 1.4 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal DUF3139 PF11337.3 EGG42473.1 - 0.28 11.4 1.9 0.44 10.8 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) Peptidase_M1 PF01433.15 EGG42474.1 - 3.5e-138 460.9 5.5 4.9e-138 460.4 3.8 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGG42474.1 - 3.6e-58 197.3 0.3 8.6e-58 196.0 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGG42474.1 - 1.4e-19 70.3 0.1 2.9e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2265 PF10023.4 EGG42474.1 - 0.016 14.4 0.0 0.033 13.3 0.0 1.6 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) B12-binding PF02310.14 EGG42475.1 - 1.4e-18 66.8 0.1 1.7e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 B12 binding domain Ocnus PF05005.10 EGG42475.1 - 0.013 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) Isochorismatase PF00857.15 EGG42475.1 - 0.039 13.8 0.1 17 5.2 0.1 2.9 1 1 1 3 3 3 0 Isochorismatase family RsmJ PF04378.8 EGG42475.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ PcrB PF01884.12 EGG42475.1 - 0.091 11.9 1.5 0.2 10.9 0.1 1.8 1 1 1 2 2 2 0 PcrB family IlvN PF07991.7 EGG42476.1 - 5.3e-67 224.3 0.4 7.3e-67 223.8 0.3 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EGG42476.1 - 1e-48 164.9 0.1 1.5e-48 164.3 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EGG42476.1 - 1.5e-06 27.4 0.1 2.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGG42476.1 - 4.1e-06 26.7 0.2 4.8e-05 23.2 0.1 2.4 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGG42476.1 - 6.6e-05 23.2 0.1 0.00018 21.8 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EGG42476.1 - 0.005 16.6 0.2 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CTP_transf_2 PF01467.21 EGG42477.1 - 4.8e-14 52.6 0.0 6.9e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase HIGH_NTase1 PF05636.6 EGG42477.1 - 0.0012 17.9 0.1 0.016 14.2 0.0 2.3 2 1 1 3 3 3 1 HIGH Nucleotidyl Transferase Citrate_ly_lig PF08218.6 EGG42477.1 - 0.002 17.6 0.0 0.047 13.1 0.0 2.1 1 1 1 2 2 2 1 Citrate lyase ligase C-terminal domain NTNH_C PF08470.5 EGG42477.1 - 0.015 14.9 0.1 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal MazG PF03819.12 EGG42477.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain CBS PF00571.23 EGG42478.1 - 6.5e-18 64.2 0.1 8.7e-11 41.4 0.0 2.3 2 0 0 2 2 2 2 CBS domain GTP_EFTU_D2 PF03144.20 EGG42479.1 - 1.6e-10 40.9 0.3 5.3e-10 39.2 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGG42479.1 - 0.00043 19.8 0.4 0.0015 18.1 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PHO4 PF01384.15 EGG42480.1 - 2.7e-98 328.6 40.2 3.3e-98 328.3 27.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.5 EGG42480.1 - 0.034 13.7 0.2 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain PhoU_div PF01865.11 EGG42481.1 - 1e-22 80.3 12.1 1.2e-22 80.1 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 DUF643 PF04867.7 EGG42481.1 - 0.011 16.1 2.9 0.25 11.7 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF643) COLFI PF01410.13 EGG42481.1 - 0.039 13.3 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain DXP_synthase_N PF13292.1 EGG42481.1 - 0.071 12.0 0.9 0.53 9.1 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Med4 PF10018.4 EGG42481.1 - 0.11 11.9 2.6 0.12 11.7 0.6 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 PhoU PF01895.14 EGG42481.1 - 0.11 13.0 10.9 0.19 12.1 1.6 2.6 1 1 2 3 3 3 0 PhoU domain Ferritin PF00210.19 EGG42481.1 - 0.16 11.7 3.3 0.79 9.4 2.3 2.3 1 1 0 1 1 1 0 Ferritin-like domain MCPsignal PF00015.16 EGG42481.1 - 0.42 10.1 7.0 3.8 6.9 1.9 2.5 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ThiF PF00899.16 EGG42481.1 - 0.95 9.2 5.0 1.2 8.9 0.4 2.3 1 1 1 2 2 2 0 ThiF family tRNA-synt_1e PF01406.14 EGG42481.1 - 6.1 5.8 8.1 0.82 8.7 0.3 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain 7TM_GPCR_Srab PF10292.4 EGG42482.1 - 0.024 13.3 0.3 0.027 13.1 0.2 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF726 PF05277.7 EGG42483.1 - 0.012 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF900 PF05990.7 EGG42484.1 - 1.9e-07 30.6 0.1 2.5e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EGG42484.1 - 7e-05 21.9 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EGG42484.1 - 0.00019 20.8 3.7 0.0029 16.9 2.5 2.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EGG42484.1 - 0.00021 21.0 0.0 0.00026 20.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EGG42484.1 - 0.0021 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF2305 PF10230.4 EGG42484.1 - 0.0049 16.3 0.3 0.0059 16.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF2424 PF10340.4 EGG42484.1 - 0.0056 15.3 0.3 0.0074 14.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Lipase_3 PF01764.20 EGG42484.1 - 0.074 12.6 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EGG42484.1 - 0.081 12.5 1.1 0.11 12.0 0.8 1.3 1 1 0 1 1 1 0 PGAP1-like protein VirJ PF06057.6 EGG42484.1 - 0.11 12.2 0.1 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_8 PF06259.7 EGG42484.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase Cutinase PF01083.17 EGG42484.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase tRNA-synt_1g PF09334.6 EGG42485.1 - 1e-133 445.8 1.8 1.3e-133 445.4 1.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGG42485.1 - 1.1e-18 66.6 1.6 1e-07 30.4 0.0 4.0 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EGG42485.1 - 1.7e-10 40.5 0.3 7.6e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EGG42485.1 - 4.4e-07 28.9 0.2 0.0015 17.3 0.0 2.9 2 1 1 3 3 3 2 tRNA synthetases class I (K) Anticodon_1 PF08264.8 EGG42485.1 - 9.2e-07 28.7 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA FhuF PF06276.7 EGG42485.1 - 0.0042 17.0 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter tRNA-synt_1d PF00750.14 EGG42485.1 - 0.019 13.8 0.1 1.1 8.0 0.0 2.4 1 1 1 2 2 2 0 tRNA synthetases class I (R) Endotoxin_N PF03945.9 EGG42485.1 - 0.05 12.9 0.5 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain zf-ribbon_3 PF13248.1 EGG42485.1 - 0.21 10.8 7.3 10 5.5 5.0 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-Di19 PF05605.7 EGG42485.1 - 0.62 10.2 2.5 1.4 9.0 1.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding AdoHcyase_NAD PF00670.16 EGG42486.1 - 1.6e-52 177.6 0.8 1.6e-52 177.6 0.6 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 EGG42486.1 - 2e-48 164.6 0.2 2.3e-48 164.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 EGG42486.1 - 7.4e-10 38.2 0.1 1.9e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGG42486.1 - 2.8e-06 26.8 0.1 5.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EGG42486.1 - 0.002 18.2 0.2 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EGG42486.1 - 0.0022 17.9 0.0 0.0063 16.5 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EGG42486.1 - 0.0052 16.4 1.7 0.021 14.4 0.2 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EGG42486.1 - 0.028 13.4 0.5 0.23 10.5 0.3 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 EGG42486.1 - 0.037 13.4 0.5 0.086 12.2 0.4 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF364 PF04016.7 EGG42486.1 - 0.055 12.7 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Rieske PF00355.21 EGG42487.1 - 1.6e-15 56.4 0.0 1.8e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EGG42487.1 - 1.5e-13 50.3 0.0 1.7e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_synthase PF02540.12 EGG42488.1 - 7.2e-76 254.2 0.5 8.5e-76 254.0 0.4 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 EGG42488.1 - 0.0011 17.6 0.0 0.034 12.7 0.0 2.3 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.15 EGG42488.1 - 0.0041 16.6 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EGG42488.1 - 0.0095 15.4 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGG42488.1 - 0.018 14.2 0.0 0.038 13.2 0.0 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC HTH_23 PF13384.1 EGG42488.1 - 0.022 14.3 0.0 3.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain ThiI PF02568.9 EGG42488.1 - 0.045 13.2 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA-synt_1e PF01406.14 EGG42489.1 - 7.7e-125 415.9 2.3 7.7e-125 415.9 1.6 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGG42489.1 - 1.1e-15 57.2 3.0 1.2e-09 37.2 0.7 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EGG42489.1 - 1.5e-09 37.9 0.0 4.5e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.17 EGG42489.1 - 5.5e-08 31.2 0.2 5e-06 24.8 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EGG42489.1 - 2e-06 26.7 0.2 0.031 12.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) ERp29 PF07749.7 EGG42489.1 - 0.021 15.4 6.0 0.75 10.4 0.1 3.5 2 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF1539 PF07560.6 EGG42489.1 - 0.75 9.6 7.8 22 4.9 5.4 2.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) tRNA-synt_1c PF00749.16 EGG42489.1 - 0.87 8.1 11.4 0.26 9.9 2.2 3.5 3 1 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain UVR PF02151.14 EGG42489.1 - 7.4 6.2 9.5 3 7.4 3.6 2.5 2 0 0 2 2 2 0 UvrB/uvrC motif MMR_HSR1_C PF08438.5 EGG42491.1 - 9.4e-33 112.7 0.0 2.1e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EGG42491.1 - 2.6e-15 56.3 0.1 9.4e-15 54.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 EGG42491.1 - 1.3e-07 31.3 0.0 2.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EGG42491.1 - 4.4e-05 22.7 0.1 0.0036 16.6 0.0 2.8 2 1 1 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGG42491.1 - 0.0003 20.6 0.2 0.067 13.0 0.0 2.8 2 1 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 EGG42491.1 - 0.00089 18.7 0.3 1.7 8.0 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Syntaxin-6_N PF09177.6 EGG42492.1 - 0.016 15.5 1.3 0.044 14.1 0.4 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HECT_2 PF09814.4 EGG42492.1 - 0.017 13.8 0.2 0.018 13.7 0.1 1.0 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF3492 PF11997.3 EGG42492.1 - 0.11 12.0 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CoA_binding_2 PF13380.1 EGG42493.1 - 1.1e-35 122.3 0.0 1.2e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EGG42493.1 - 3.4e-07 30.6 0.0 6.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_57 PF03065.10 EGG42493.1 - 0.03 13.2 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SpoU_sub_bind PF08032.7 EGG42493.1 - 0.049 13.8 0.2 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Phage_GPA PF05840.8 EGG42493.1 - 0.095 11.3 0.2 0.16 10.6 0.1 1.3 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) Epimerase PF01370.16 EGG42494.1 - 6.6e-25 87.9 0.0 8.6e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGG42494.1 - 3e-13 50.1 0.0 3.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGG42494.1 - 5.4e-13 48.4 0.0 2e-10 40.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EGG42494.1 - 2.5e-12 46.0 0.1 6.5e-12 44.7 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG42494.1 - 7e-08 31.7 0.0 6.4e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGG42494.1 - 6.9e-06 25.1 0.5 0.00081 18.3 0.3 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGG42494.1 - 1.8e-05 24.1 0.0 0.00035 19.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Sarcolipin PF05366.6 EGG42494.1 - 0.046 13.1 0.1 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Sarcolipin DapB_N PF01113.15 EGG42494.1 - 0.077 12.9 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EGG42494.1 - 0.096 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase HTH_45 PF14947.1 EGG42495.1 - 7.4e-05 22.4 0.3 0.00017 21.3 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4423 PF14394.1 EGG42495.1 - 0.0002 20.9 0.5 0.00035 20.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_34 PF13601.1 EGG42495.1 - 0.00061 19.7 0.3 0.0011 18.9 0.2 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.14 EGG42495.1 - 0.0011 18.5 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 EGG42495.1 - 0.0059 16.0 0.6 0.0099 15.3 0.4 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit Rio2_N PF09202.6 EGG42495.1 - 0.012 15.7 0.2 0.079 13.0 0.0 2.2 2 0 0 2 2 2 0 Rio2, N-terminal MarR_2 PF12802.2 EGG42495.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.1 EGG42495.1 - 0.028 14.7 0.1 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2317 PF10079.4 EGG42495.1 - 0.066 11.8 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF3135 PF11333.3 EGG42495.1 - 0.095 12.8 0.4 0.3 11.2 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) HemN_C PF06969.11 EGG42495.1 - 0.1 12.6 0.1 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 HemN C-terminal domain Wbp11 PF09429.5 EGG42495.1 - 4.8 7.2 8.2 24 4.9 2.1 2.1 1 1 1 2 2 2 0 WW domain binding protein 11 BPL_LplA_LipB PF03099.14 EGG42496.1 - 7e-23 80.9 0.2 1.6e-20 73.3 0.0 2.4 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.7 EGG42496.1 - 4.2e-16 58.3 0.2 1.1e-15 56.9 0.2 1.8 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.12 EGG42496.1 - 5.4e-09 35.5 0.8 1.1e-08 34.5 0.6 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Sec15 PF04091.7 EGG42496.1 - 0.013 14.8 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like HTH_24 PF13412.1 EGG42496.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding UPF0122 PF04297.9 EGG42496.1 - 0.035 14.1 1.3 0.06 13.3 0.0 2.1 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Rrf2 PF02082.15 EGG42496.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator AATF-Che1 PF13339.1 EGG42497.1 - 0.0025 17.9 4.7 0.0033 17.5 3.3 1.2 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DUF948 PF06103.6 EGG42497.1 - 0.0055 16.5 1.1 0.039 13.8 0.3 2.2 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EGG42497.1 - 0.013 14.6 0.7 0.048 12.8 0.6 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein PH_4 PF15404.1 EGG42497.1 - 0.027 13.9 1.4 0.034 13.6 1.0 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4375 PF14300.1 EGG42497.1 - 0.04 13.9 0.1 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Syntaxin-6_N PF09177.6 EGG42497.1 - 0.059 13.7 2.6 0.18 12.2 1.5 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 EGG42497.1 - 0.077 12.8 0.2 17 5.4 0.0 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EGG42497.1 - 0.096 12.5 0.7 0.14 11.9 0.5 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 EGG42497.1 - 2.3 8.4 10.2 9.7 6.4 7.1 1.9 1 1 0 1 1 1 0 Syntaxin TPR_11 PF13414.1 EGG42498.1 - 2.2e-08 33.6 1.3 0.00026 20.5 0.0 2.6 1 1 1 2 2 2 2 TPR repeat Peptidase_M10 PF00413.19 EGG42498.1 - 6.6e-08 32.4 0.1 1.9e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 Matrixin TPR_1 PF00515.23 EGG42498.1 - 1.3e-07 30.9 0.1 0.014 14.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG42498.1 - 2e-07 30.3 0.0 0.034 14.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Reprolysin_5 PF13688.1 EGG42498.1 - 3.1e-05 23.9 0.1 4.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 TPR_17 PF13431.1 EGG42498.1 - 8.4e-05 22.4 0.1 4.1 7.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Reprolysin_2 PF13574.1 EGG42498.1 - 0.0003 20.8 0.1 0.00059 19.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 EGG42498.1 - 0.00091 19.0 0.7 0.0023 17.7 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M54 TPR_8 PF13181.1 EGG42498.1 - 0.00097 18.7 1.1 0.35 10.7 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42498.1 - 0.0014 19.0 0.0 11 7.0 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42498.1 - 0.0041 17.4 0.0 0.41 11.0 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat Peptidase_M57 PF12388.3 EGG42498.1 - 0.0041 16.4 0.1 0.01 15.1 0.1 1.7 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase TPR_16 PF13432.1 EGG42498.1 - 0.0042 17.7 0.0 0.12 13.0 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EGG42498.1 - 0.0043 16.2 0.1 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit Peptidase_M43 PF05572.8 EGG42498.1 - 0.012 15.2 0.2 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EGG42498.1 - 0.013 16.0 0.4 0.026 15.0 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EGG42498.1 - 0.017 14.0 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 EGG42498.1 - 0.03 13.8 0.2 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TPR_6 PF13174.1 EGG42498.1 - 0.033 14.6 0.2 1.1 9.8 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG42498.1 - 0.058 13.2 0.0 25 4.8 0.0 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Reprolysin PF01421.14 EGG42498.1 - 0.077 12.5 0.3 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease TPR_12 PF13424.1 EGG42498.1 - 0.15 11.9 0.0 1 9.3 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat FUN14 PF04930.10 EGG42498.1 - 1.6 9.0 5.4 0.28 11.4 0.4 2.2 3 0 0 3 3 2 0 FUN14 family TFIIB PF00382.14 EGG42499.1 - 8.4e-34 115.2 6.7 3.5e-18 65.1 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG42499.1 - 6e-13 47.8 1.4 1.1e-12 47.0 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EGG42499.1 - 3.5e-05 23.3 0.5 0.00041 19.9 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Peptidase_M13_N PF05649.8 EGG42499.1 - 0.0058 15.7 1.4 0.21 10.5 0.4 2.5 2 1 1 3 3 3 1 Peptidase family M13 Lar_restr_allev PF14354.1 EGG42499.1 - 0.012 15.9 0.5 0.035 14.3 0.4 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar RRN7 PF11781.3 EGG42499.1 - 0.021 14.3 0.4 0.047 13.1 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 OrfB_Zn_ribbon PF07282.6 EGG42499.1 - 0.034 13.7 0.9 0.081 12.5 0.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EGG42499.1 - 0.052 13.3 0.3 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 EGG42499.1 - 0.053 12.7 5.0 0.21 10.8 3.7 1.8 1 1 1 2 2 2 0 zinc-ribbon domain Ribosomal_S27e PF01667.12 EGG42499.1 - 0.058 12.9 0.4 0.13 11.7 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 Translin PF01997.11 EGG42499.1 - 0.06 12.9 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Translin family zf-C4_Topoisom PF01396.14 EGG42499.1 - 0.89 9.1 3.8 0.63 9.5 1.4 1.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-NADH-PPase PF09297.6 EGG42499.1 - 5.5 6.5 5.9 3.4 7.2 0.4 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Methyltransf_FA PF12248.3 EGG42500.1 - 0.1 12.6 0.1 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Farnesoic acid 0-methyl transferase Pribosyltran PF00156.22 EGG42501.1 - 1.1e-08 34.7 0.1 5.7e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Phosphoribosyl transferase domain DUF956 PF06115.6 EGG42501.1 - 0.048 13.2 0.1 9.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF956) FF PF01846.14 EGG42501.1 - 0.075 12.9 0.2 9.9 6.2 0.1 2.4 2 0 0 2 2 2 0 FF domain PHA_synth_III_E PF09712.5 EGG42503.1 - 1.3e-09 37.9 0.0 1.6e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF4200 PF13863.1 EGG42503.1 - 0.025 14.5 9.0 0.045 13.6 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 EGG42503.1 - 0.028 14.4 2.3 0.028 14.4 1.6 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phasin PF05597.6 EGG42503.1 - 0.045 13.5 1.4 0.11 12.2 0.9 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) KxDL PF10241.4 EGG42503.1 - 0.065 13.1 2.3 1.8 8.4 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein SPT16 PF08644.6 EGG42503.1 - 0.066 13.0 1.2 0.12 12.2 0.8 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Bacillus_HBL PF05791.6 EGG42503.1 - 0.098 12.0 5.0 0.26 10.6 0.1 2.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Microtub_assoc PF07989.6 EGG42503.1 - 0.11 12.3 5.1 2.9 7.7 1.6 2.3 2 0 0 2 2 2 0 Microtubule associated IFP_35_N PF07334.8 EGG42503.1 - 0.2 11.6 12.3 0.14 12.1 3.4 2.8 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Uds1 PF15456.1 EGG42503.1 - 1.1 9.3 5.3 0.75 9.7 1.5 2.1 2 1 0 2 2 2 0 Up-regulated During Septation PhaC_N PF07167.8 EGG42504.1 - 2.2e-12 46.7 0.1 4.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.15 EGG42504.1 - 6.6e-10 38.9 0.0 8.9e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3141 PF11339.3 EGG42504.1 - 2.2e-06 26.3 0.0 3.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) Abhydrolase_6 PF12697.2 EGG42504.1 - 2.6e-06 27.4 0.0 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG42504.1 - 2.9e-05 23.8 0.0 0.00011 22.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EGG42504.1 - 0.0015 17.8 0.0 0.009 15.3 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EGG42504.1 - 0.0046 16.6 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PHB_depo_C PF06850.6 EGG42504.1 - 0.0083 15.3 0.0 0.045 12.9 0.0 2.2 1 1 0 1 1 1 1 PHB de-polymerase C-terminus DegV PF02645.11 EGG42505.1 - 0.011 14.8 0.5 0.018 14.1 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 RIH_assoc PF08454.6 EGG42505.1 - 0.042 13.4 2.6 0.073 12.7 1.6 1.5 1 1 0 1 1 1 0 RyR and IP3R Homology associated Rabaptin PF03528.10 EGG42505.1 - 0.061 13.2 0.6 0.16 11.9 0.4 1.8 1 1 0 1 1 1 0 Rabaptin Tweety PF04906.8 EGG42505.1 - 0.12 10.7 1.3 0.14 10.4 0.9 1.2 1 0 0 1 1 1 0 Tweety Fib_alpha PF08702.5 EGG42505.1 - 0.41 10.7 3.6 6.4 6.8 2.8 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.9 EGG42505.1 - 0.78 9.3 7.4 1.2 8.8 0.8 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Antitoxin-MazE PF04014.13 EGG42506.1 - 0.00014 21.4 0.1 0.00024 20.7 0.1 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE LLC1 PF14945.1 EGG42506.1 - 0.036 14.3 0.1 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Tantalus PF15386.1 EGG42506.1 - 0.44 10.3 3.6 8.8 6.1 0.0 2.7 2 1 1 3 3 3 0 Drosophila Tantalus-like Abhydrolase_6 PF12697.2 EGG42507.1 - 1.3e-38 133.2 0.0 1.5e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG42507.1 - 2.4e-25 89.4 0.0 2.4e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG42507.1 - 5.4e-16 58.6 0.0 1.9e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGG42507.1 - 5.3e-06 26.0 0.0 0.095 12.1 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EGG42507.1 - 5.8e-05 22.7 0.0 0.027 14.0 0.0 2.8 1 1 0 1 1 1 1 Serine hydrolase Ndr PF03096.9 EGG42507.1 - 7.8e-05 21.2 0.0 0.00011 20.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EGG42507.1 - 0.00034 20.3 0.0 0.00079 19.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 EGG42507.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.7 EGG42507.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Usp PF00582.21 EGG42508.1 - 4.2e-24 85.3 0.0 5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family UL97 PF06734.7 EGG42508.1 - 0.077 12.3 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 UL97 PMSR PF01625.16 EGG42509.1 - 1.8e-66 222.8 0.8 2e-66 222.7 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF1033 PF06279.6 EGG42509.1 - 0.041 13.7 0.4 0.06 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) DUF2517 PF10725.4 EGG42511.1 - 0.17 11.5 0.2 0.47 10.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Methyltransf_11 PF08241.7 EGG42512.1 - 4.8e-11 43.0 0.0 7.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG42512.1 - 4.3e-06 26.3 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG42512.1 - 0.00058 20.2 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG42512.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGG42512.1 - 0.0025 17.4 0.0 0.0052 16.4 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EGG42512.1 - 0.093 12.1 0.0 0.76 9.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain ADK PF00406.17 EGG42512.1 - 0.12 12.2 0.1 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase RDD PF06271.7 EGG42513.1 - 1.7e-12 47.4 0.6 1.9e-12 47.2 0.4 1.1 1 0 0 1 1 1 1 RDD family Toxin_2 PF00451.14 EGG42515.1 - 0.1 12.6 1.2 77 3.5 0.0 3.0 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Aminotran_3 PF00202.16 EGG42517.1 - 1.4e-47 162.2 0.0 1.7e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TPR_11 PF13414.1 EGG42518.1 - 2.4e-35 120.0 18.8 6.6e-12 44.9 0.6 4.4 1 1 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 EGG42518.1 - 9.1e-35 116.8 20.6 2.8e-06 26.7 0.0 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 EGG42518.1 - 3.8e-34 113.8 10.1 0.00021 20.9 0.0 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGG42518.1 - 3.5e-25 88.0 0.0 9.8e-08 32.4 0.0 4.4 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42518.1 - 6.4e-25 85.2 13.1 2.3e-05 24.2 0.2 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EGG42518.1 - 2.1e-23 81.1 0.9 0.054 13.9 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42518.1 - 1.2e-21 75.1 0.0 0.0011 19.4 0.0 7.1 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGG42518.1 - 1.5e-21 76.1 4.9 1.9e-07 30.9 0.1 4.6 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42518.1 - 4.2e-21 75.0 8.4 4.6e-06 26.8 0.2 4.6 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42518.1 - 6.9e-21 72.4 19.0 0.00042 19.8 0.0 7.1 6 1 1 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 EGG42518.1 - 3e-16 59.3 7.9 3.1e-06 27.2 0.7 3.5 3 1 1 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGG42518.1 - 1.7e-11 43.8 0.0 0.00073 19.3 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGG42518.1 - 3.3e-08 32.7 0.1 0.056 13.2 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG42518.1 - 1.1e-07 31.5 6.6 0.17 11.7 0.0 5.2 3 1 3 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EGG42518.1 - 3.1e-06 26.9 2.0 2.4 8.2 0.2 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGG42518.1 - 1.4e-05 25.1 3.2 0.15 12.1 0.1 3.8 2 2 3 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 EGG42518.1 - 1.5e-05 23.9 5.7 0.091 11.5 0.1 3.3 1 1 3 4 4 4 3 NMDA receptor-regulated protein 1 MIT PF04212.13 EGG42518.1 - 9.7e-05 22.1 9.2 2.7 7.9 0.1 5.7 5 2 0 5 5 5 2 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 EGG42518.1 - 0.0012 17.7 0.7 0.0044 15.8 0.1 1.9 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) MerR_1 PF13411.1 EGG42518.1 - 0.0032 17.1 0.2 0.52 10.1 0.0 2.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein PPR PF01535.15 EGG42518.1 - 0.0073 16.2 1.4 22 5.3 0.0 4.9 4 0 0 4 4 4 0 PPR repeat PPTA PF01239.17 EGG42518.1 - 0.012 14.9 1.8 8 6.0 0.0 4.2 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat TOM20_plant PF06552.7 EGG42518.1 - 0.017 14.7 1.5 8.1 5.9 0.0 3.8 1 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.7 EGG42518.1 - 0.046 13.5 3.2 2.3 8.1 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 EGG42518.1 - 0.089 12.6 0.2 2.5 7.9 0.0 3.3 2 2 2 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPPII_N PF12583.3 EGG42518.1 - 0.18 11.9 5.8 1.9 8.6 0.3 3.6 3 1 1 4 4 4 0 Tripeptidyl peptidase II N terminal Cupin_2 PF07883.6 EGG42519.1 - 5.1e-08 32.3 0.1 3.1e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EGG42519.1 - 3.7e-06 26.4 0.0 4.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.11 EGG42519.1 - 0.00064 19.1 0.1 0.00078 18.9 0.1 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_8 PF13621.1 EGG42519.1 - 0.00074 19.0 0.1 0.0016 18.0 0.1 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGG42519.1 - 0.0035 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.14 EGG42519.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 AraC-like ligand binding domain MAP PF03642.8 EGG42519.1 - 0.08 13.1 4.3 0.11 12.6 0.6 2.8 3 1 0 3 3 3 0 MAP domain Cupin_2 PF07883.6 EGG42520.1 - 1.9e-12 46.5 0.0 3.8e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.13 EGG42520.1 - 1.3e-09 37.8 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_1 PF00190.17 EGG42520.1 - 5.5e-05 22.6 0.0 8.5e-05 22.0 0.0 1.3 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.14 EGG42520.1 - 0.00039 20.1 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EGG42520.1 - 0.0004 19.7 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.3 EGG42520.1 - 0.0018 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like Ectoine_synth PF06339.7 EGG42520.1 - 0.0022 17.9 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Ectoine synthase GPI PF06560.6 EGG42520.1 - 0.0097 14.9 0.0 0.021 13.8 0.0 1.5 1 1 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_5 PF06172.6 EGG42520.1 - 0.025 14.4 0.0 0.035 14.0 0.0 1.4 1 1 0 1 1 1 0 Cupin superfamily (DUF985) DnaJ PF00226.26 EGG42521.1 - 1.2e-14 53.7 0.8 2.6e-14 52.6 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Fer4_15 PF13459.1 EGG42521.1 - 1.4e-10 41.5 0.8 4.3e-10 40.0 0.6 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.1 EGG42521.1 - 3.4e-10 40.1 1.3 9.7e-10 38.6 0.9 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.6 EGG42521.1 - 0.00023 20.9 1.2 0.00056 19.6 0.8 1.6 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_7 PF12838.2 EGG42521.1 - 0.023 15.0 0.5 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Phytochelatin PF05023.9 EGG42521.1 - 0.055 12.4 0.3 0.084 11.8 0.2 1.2 1 0 0 1 1 1 0 Phytochelatin synthase Fer4 PF00037.22 EGG42521.1 - 0.082 12.5 9.9 0.81 9.3 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain SRR PF07709.6 EGG42521.1 - 5.1 7.7 5.9 3.5 8.2 0.1 3.3 3 0 0 3 3 3 0 Seven Residue Repeat HIT PF01230.18 EGG42522.1 - 1.3e-22 80.1 0.7 1.6e-22 79.8 0.5 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGG42522.1 - 4.1e-12 46.3 0.1 5.9e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGG42522.1 - 0.0014 18.2 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.12 EGG42522.1 - 0.054 13.0 0.2 0.064 12.7 0.1 1.3 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain zf-H2C2_5 PF13909.1 EGG42524.1 - 0.00053 20.0 0.9 0.00075 19.5 0.6 1.3 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EGG42524.1 - 0.074 13.4 3.1 0.11 12.8 2.1 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.10 EGG42524.1 - 0.15 11.8 3.5 0.25 11.1 2.4 1.4 1 0 0 1 1 1 0 BED zinc finger HATPase_c PF02518.21 EGG42525.1 - 1.4e-25 89.1 0.4 2.8e-25 88.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG42525.1 - 5.6e-11 42.2 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG42525.1 - 1.8e-08 34.0 0.8 1.8e-08 34.0 0.6 2.0 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 EGG42525.1 - 0.0017 18.0 0.6 0.0038 16.8 0.4 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG42525.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Cyc-maltodext_N PF09087.6 EGG42525.1 - 0.088 12.7 1.6 3.8 7.5 0.0 3.1 3 0 0 3 3 3 0 Cyclomaltodextrinase, N-terminal RIG-I_C-RD PF11648.3 EGG42526.1 - 0.0077 16.1 0.6 0.015 15.1 0.2 1.7 2 0 0 2 2 2 1 C-terminal domain of RIG-I Yippee-Mis18 PF03226.9 EGG42526.1 - 0.011 15.7 0.8 0.017 15.1 0.5 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CpG_bind_C PF12269.3 EGG42526.1 - 0.025 14.0 1.2 0.034 13.6 0.8 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Capsule_synth PF05159.9 EGG42526.1 - 0.05 13.0 0.1 0.067 12.6 0.1 1.1 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EGG42527.1 - 1.4e-64 217.0 0.4 1.4e-64 217.0 0.3 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGG42527.1 - 2.7e-33 114.2 0.2 3.4e-26 91.4 0.1 2.7 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EGG42527.1 - 2.1e-07 30.7 0.2 3.5e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EGG42527.1 - 6.3e-05 22.8 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGG42527.1 - 0.011 16.1 1.6 0.04 14.3 1.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EGG42527.1 - 0.052 12.9 0.2 0.093 12.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 EGG42527.1 - 0.35 10.2 3.3 21 4.4 2.3 2.3 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF643 PF04867.7 EGG42527.1 - 1.9 8.8 8.2 0.25 11.7 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF643) Lysine_decarbox PF03641.9 EGG42528.1 - 1.1e-06 28.5 0.0 2.8e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Possible lysine decarboxylase DNA_processg_A PF02481.10 EGG42528.1 - 0.00024 20.0 0.2 0.0064 15.4 0.1 2.2 2 0 0 2 2 2 1 DNA recombination-mediator protein A DAGK_cat PF00781.19 EGG42528.1 - 0.0043 16.4 2.1 0.26 10.7 0.1 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain MoCo_carrier PF12694.2 EGG42528.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative molybdenum carrier Nuc_deoxyrib_tr PF05014.10 EGG42528.1 - 0.042 13.7 0.1 0.082 12.7 0.0 1.7 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase zf-C4pol PF14260.1 EGG42529.1 - 0.0069 16.3 8.2 0.64 10.0 0.5 3.3 2 1 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.16 EGG42529.1 - 0.018 14.9 18.3 1.3e+02 2.5 12.7 3.4 1 1 0 1 1 1 0 FYVE zinc finger Ribosomal_S14 PF00253.16 EGG42529.1 - 0.019 14.3 7.3 1.6 8.2 0.6 4.0 3 1 0 3 3 3 0 Ribosomal protein S14p/S29e DUF3179 PF11376.3 EGG42529.1 - 0.091 11.9 0.1 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3179) Cytochrome_C7 PF14522.1 EGG42529.1 - 0.091 12.3 17.1 0.07 12.7 3.5 3.0 2 1 0 2 2 2 0 Cytochrome c7 zf-CHY PF05495.7 EGG42529.1 - 0.12 12.5 18.2 0.48 10.6 3.6 3.1 2 1 0 3 3 3 0 CHY zinc finger DZR PF12773.2 EGG42529.1 - 0.29 10.9 17.9 7.9e+03 -3.3 12.6 3.5 1 1 0 1 1 1 0 Double zinc ribbon DUF4428 PF14471.1 EGG42529.1 - 0.54 10.0 23.5 1.6 8.5 0.5 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4428) zf-C3HC4_3 PF13920.1 EGG42529.1 - 0.87 9.3 14.1 6 6.6 0.3 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EGG42529.1 - 1.3 8.9 14.9 2.9 7.8 1.7 2.7 1 1 0 2 2 2 0 FYVE-type zinc finger zf-met PF12874.2 EGG42529.1 - 3.4 8.0 7.0 2.8 8.2 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Cytochrom_c3_2 PF14537.1 EGG42529.1 - 5.3 7.4 16.5 4.6e+02 1.2 11.5 3.1 1 1 0 1 1 1 0 Cytochrome c3 C1_1 PF00130.17 EGG42529.1 - 5.4 6.8 20.4 0.6 9.8 1.2 3.5 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.7 EGG42529.1 - 5.8 6.3 8.6 8.9 5.7 0.2 3.5 4 0 0 4 4 4 0 TFIIB zinc-binding zf-C2H2_4 PF13894.1 EGG42530.1 - 2.3e-08 33.7 6.5 0.0011 19.1 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG42530.1 - 7.7e-08 32.2 10.1 0.00063 19.9 1.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGG42530.1 - 2.1e-06 27.7 10.8 0.00063 19.8 1.3 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EGG42530.1 - 5.6e-05 23.1 11.4 0.0015 18.5 1.1 2.3 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EGG42530.1 - 5.7e-05 22.8 7.7 0.0092 15.8 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGG42530.1 - 7e-05 22.8 7.6 0.023 14.8 0.4 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EGG42530.1 - 0.00028 20.9 14.5 0.0079 16.4 0.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain DUF629 PF04780.7 EGG42530.1 - 0.00076 18.1 9.7 0.032 12.7 0.9 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF629) Prok-RING_1 PF14446.1 EGG42530.1 - 0.015 15.0 2.9 0.93 9.2 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.2 EGG42530.1 - 0.017 15.2 9.8 0.19 11.8 1.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RIG-I_C-RD PF11648.3 EGG42530.1 - 0.018 14.9 1.9 0.75 9.6 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I ZZ PF00569.12 EGG42530.1 - 0.03 13.8 1.9 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type DUF1644 PF07800.7 EGG42530.1 - 0.035 13.9 3.1 0.038 13.8 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) zf-FCS PF06467.9 EGG42530.1 - 0.039 13.5 4.7 2.1 8.0 0.3 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-3CxxC PF13695.1 EGG42530.1 - 0.045 13.9 2.8 0.049 13.8 1.9 1.1 1 0 0 1 1 1 0 Zinc-binding domain Cor1 PF04803.7 EGG42530.1 - 0.046 13.4 1.9 0.05 13.3 1.3 1.1 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region zf-Di19 PF05605.7 EGG42530.1 - 0.065 13.3 7.4 0.15 12.2 5.1 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Endonuclease_7 PF02945.10 EGG42530.1 - 0.12 12.0 1.1 0.15 11.8 0.7 1.1 1 0 0 1 1 1 0 Recombination endonuclease VII DUF3268 PF11672.3 EGG42530.1 - 0.15 12.1 1.2 0.18 11.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) C1_4 PF07975.7 EGG42530.1 - 0.16 12.0 6.4 0.27 11.2 4.3 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain Ribosomal_L44 PF00935.14 EGG42530.1 - 0.16 11.9 3.7 0.87 9.6 0.4 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 LIM PF00412.17 EGG42530.1 - 0.25 11.4 4.9 1.3 9.1 0.3 2.1 1 1 0 1 1 1 0 LIM domain Zn-ribbon_8 PF09723.5 EGG42530.1 - 0.32 10.9 4.7 1.1 9.2 0.6 2.2 2 0 0 2 2 2 0 Zinc ribbon domain PyrI_C PF02748.10 EGG42530.1 - 0.35 10.3 3.8 0.26 10.7 1.2 1.8 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_2 PF03107.11 EGG42530.1 - 0.35 11.0 4.3 4.2 7.5 0.4 2.2 2 0 0 2 2 2 0 C1 domain Prok-RING_2 PF14445.1 EGG42530.1 - 0.48 10.4 4.1 4 7.4 2.8 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 Zn_Tnp_IS1595 PF12760.2 EGG42530.1 - 0.49 10.2 3.3 1.3 8.9 2.3 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EGG42530.1 - 1 9.1 8.0 1 9.2 2.1 2.2 1 1 1 2 2 2 0 BED zinc finger Evr1_Alr PF04777.8 EGG42530.1 - 1.8 8.5 6.3 28 4.6 4.4 2.0 1 1 0 1 1 1 0 Erv1 / Alr family Rpr2 PF04032.11 EGG42530.1 - 2.3 8.1 4.8 4.6 7.1 3.0 1.6 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-DNL PF05180.7 EGG42530.1 - 3.5 7.4 7.9 12 5.6 4.4 2.2 1 1 1 2 2 2 0 DNL zinc finger DNA_RNApol_7kD PF03604.8 EGG42531.1 - 0.0005 19.4 2.2 0.0011 18.3 1.6 1.6 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S10 PF00338.17 EGG42532.1 - 1.4e-25 88.9 0.0 1.5e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GTP_EFTU PF00009.22 EGG42533.1 - 1.1e-47 161.8 0.1 1.6e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGG42533.1 - 1.2e-31 108.7 0.7 3.6e-31 107.2 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGG42533.1 - 4.9e-17 61.8 1.2 1.3e-16 60.4 0.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGG42533.1 - 6.6e-08 32.0 0.8 1.4e-07 31.0 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGG42533.1 - 0.0035 17.2 0.0 0.0088 15.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGG42533.1 - 0.07 13.6 0.1 0.27 11.7 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein FBPase_3 PF01950.11 EGG42534.1 - 4.5e-158 526.0 0.0 5.1e-158 525.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase MFS_1 PF07690.11 EGG42535.1 - 0.0038 15.9 1.0 0.0044 15.7 0.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily YrhC PF14143.1 EGG42535.1 - 0.11 12.4 0.9 0.19 11.7 0.6 1.5 1 0 0 1 1 1 0 YrhC-like protein DNA_ligase_A_M PF01068.16 EGG42536.1 - 6.1e-59 198.7 1.1 1.2e-58 197.8 0.8 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGG42536.1 - 5.4e-46 156.6 2.0 5.4e-46 156.6 1.4 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGG42536.1 - 2.2e-21 76.0 0.0 4.7e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EGG42536.1 - 0.1 12.2 0.1 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 DNA ligase OB-like domain PhoU_div PF01865.11 EGG42537.1 - 2e-19 69.6 11.4 2.3e-19 69.3 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.14 EGG42537.1 - 0.0029 17.9 13.9 0.013 15.9 1.9 3.0 2 2 2 4 4 4 2 PhoU domain LXG PF04740.7 EGG42537.1 - 0.017 14.8 6.7 0.032 14.0 0.3 2.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily TerB PF05099.8 EGG42537.1 - 0.09 12.5 0.6 0.27 10.9 0.1 2.0 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF458 PF04308.7 EGG42537.1 - 0.14 11.8 5.0 0.29 10.8 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF458) MCPsignal PF00015.16 EGG42537.1 - 0.2 11.1 11.3 5.5 6.4 6.7 3.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_I PF06008.9 EGG42537.1 - 0.22 10.8 7.4 0.048 12.9 0.6 2.5 1 1 1 2 2 2 0 Laminin Domain I Reo_sigmaC PF04582.7 EGG42537.1 - 0.37 9.9 3.0 0.94 8.5 0.7 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein tRNA_int_endo PF01974.12 EGG42538.1 - 1.6e-26 91.9 0.0 2.4e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGG42538.1 - 8.5e-17 60.4 0.0 1.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain adh_short PF00106.20 EGG42541.1 - 1.8e-26 93.0 0.0 1e-20 74.3 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EGG42541.1 - 2e-13 50.6 1.3 2.2e-09 37.4 0.0 3.7 4 1 0 4 4 4 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG42541.1 - 2.3e-12 46.9 0.0 1.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EGG42541.1 - 3.1e-08 33.3 0.0 2.7e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGG42541.1 - 0.018 13.9 0.1 0.036 12.9 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGG42541.1 - 0.022 14.7 0.1 0.16 11.9 0.0 2.5 2 1 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 EGG42541.1 - 0.052 13.9 0.2 0.24 11.8 0.2 2.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RNA_pol_Rbc25 PF08292.7 EGG42542.1 - 0.0085 16.2 0.2 0.052 13.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 DUF3608 PF12257.3 EGG42543.1 - 0.066 12.1 1.2 0.075 11.9 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) Reprolysin_2 PF13574.1 EGG42544.1 - 9.4e-05 22.5 0.0 0.00019 21.5 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EGG42544.1 - 9.8e-05 22.1 1.3 0.0014 18.3 0.8 2.5 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EGG42544.1 - 0.00035 19.5 0.0 0.00064 18.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M43 PF05572.8 EGG42544.1 - 0.00037 20.1 0.1 0.0012 18.5 0.1 1.8 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 EGG42544.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGG42544.1 - 0.0053 16.6 0.1 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EGG42544.1 - 0.0065 16.9 0.1 0.023 15.2 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EGG42544.1 - 0.018 14.4 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.6 EGG42544.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M57 PF12388.3 EGG42544.1 - 0.052 12.8 0.2 0.1 11.8 0.1 1.5 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1025 PF06262.6 EGG42544.1 - 0.087 12.6 0.2 0.29 10.9 0.1 1.9 1 1 0 1 1 1 0 Possibl zinc metallo-peptidase TauE PF01925.14 EGG42545.1 - 2.2e-50 171.3 34.5 2.8e-50 171.0 23.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE PMP22_Claudin PF00822.15 EGG42545.1 - 0.94 9.1 7.2 0.12 12.0 1.3 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF3353 PF11833.3 EGG42545.1 - 7.6 5.9 16.4 0.23 10.8 2.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) Nup153 PF08604.5 EGG42546.1 - 0.026 13.2 0.3 0.05 12.2 0.3 1.3 2 0 0 2 2 2 0 Nucleoporin Nup153-like DUF192 PF02643.10 EGG42547.1 - 6.6e-30 102.9 0.0 8.1e-30 102.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 YolD PF08863.5 EGG42548.1 - 0.022 14.6 2.3 0.82 9.5 0.2 2.2 1 1 1 2 2 2 0 YolD-like protein Claudin_2 PF13903.1 EGG42550.1 - 4.6e-05 23.1 1.4 5.2e-05 23.0 1.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 EGG42550.1 - 0.00071 19.6 4.3 0.00071 19.6 3.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) DUF981 PF06168.6 EGG42550.1 - 0.019 14.7 1.2 0.024 14.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) PEMT PF04191.8 EGG42550.1 - 0.063 13.3 0.5 0.063 13.3 0.3 1.9 1 1 1 2 2 2 0 Phospholipid methyltransferase HlyIII PF03006.15 EGG42550.1 - 0.09 12.1 2.4 0.11 11.8 1.6 1.1 1 0 0 1 1 1 0 Haemolysin-III related SUR7 PF06687.7 EGG42550.1 - 0.13 11.7 2.6 0.16 11.5 1.8 1.1 1 0 0 1 1 1 0 SUR7/PalI family ABC2_membrane_3 PF12698.2 EGG42550.1 - 0.22 10.5 8.5 0.24 10.4 5.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Tetraspannin PF00335.15 EGG42550.1 - 0.44 9.7 4.6 0.44 9.7 3.2 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2929 PF11151.3 EGG42550.1 - 2.2 8.4 7.8 13 5.9 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2929) MgtE PF01769.11 EGG42550.1 - 2.9 8.1 8.9 0.45 10.8 3.7 1.4 2 0 0 2 2 2 0 Divalent cation transporter Sugar_tr PF00083.19 EGG42551.1 - 9.5e-36 123.3 31.9 6e-26 91.0 8.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGG42551.1 - 2.1e-34 118.8 34.9 2.1e-34 118.8 24.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGG42551.1 - 1.1e-06 27.3 25.1 7.3e-06 24.6 7.1 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EGG42551.1 - 4.5e-06 26.3 4.6 0.00013 21.7 0.7 3.1 2 0 0 2 2 2 2 MFS_1 like family Spore_GerAC PF05504.6 EGG42552.1 - 0.18 11.5 5.8 0.084 12.6 2.1 1.7 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal DUF2874 PF11396.3 EGG42554.1 - 0.12 12.3 0.2 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) Fe_dep_repress PF01325.14 EGG42555.1 - 3.4e-17 62.1 1.7 5.3e-17 61.5 1.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.10 EGG42555.1 - 1e-16 60.3 0.1 1.8e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_27 PF13463.1 EGG42555.1 - 4.1e-05 23.8 0.0 0.00015 22.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.2 EGG42555.1 - 4.4e-05 23.0 0.0 7.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 EGG42555.1 - 7.1e-05 22.4 0.2 0.00014 21.4 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.1 EGG42555.1 - 0.0001 21.8 0.1 0.001 18.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_24 PF13412.1 EGG42555.1 - 0.00015 21.1 0.1 0.00035 19.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 EGG42555.1 - 0.00024 20.7 0.1 0.00072 19.2 0.0 1.7 2 0 0 2 2 2 1 MarR family DUF2250 PF10007.4 EGG42555.1 - 0.00025 20.8 0.2 0.00043 20.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_45 PF14947.1 EGG42555.1 - 0.00054 19.7 0.9 0.0016 18.2 0.5 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix HTH_Crp_2 PF13545.1 EGG42555.1 - 0.00056 19.6 0.0 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_12 PF08461.5 EGG42555.1 - 0.0018 17.9 0.2 0.0034 17.0 0.1 1.6 1 1 0 1 1 1 1 Ribonuclease R winged-helix domain TFIIE_alpha PF02002.12 EGG42555.1 - 0.0079 15.6 0.4 0.037 13.5 0.1 1.9 1 1 1 2 2 2 1 TFIIE alpha subunit HTH_1 PF00126.22 EGG42555.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.8 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Ribosomal_S19e PF01090.14 EGG42555.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e LexA_DNA_bind PF01726.11 EGG42555.1 - 0.027 14.0 0.0 0.08 12.5 0.0 1.8 2 0 0 2 2 2 0 LexA DNA binding domain FeoC PF09012.5 EGG42555.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator GntR PF00392.16 EGG42555.1 - 0.045 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.5 EGG42555.1 - 0.047 13.2 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Rio2_N PF09202.6 EGG42555.1 - 0.071 13.1 0.1 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Rio2, N-terminal HTH_28 PF13518.1 EGG42555.1 - 0.08 12.9 0.0 0.93 9.5 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2624 PF11116.3 EGG42555.1 - 0.11 12.9 0.3 0.19 12.2 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) A2M_N PF01835.14 EGG42556.1 - 0.0018 18.4 0.1 0.011 15.9 0.0 2.4 2 1 1 3 3 3 1 MG2 domain Chordopox_G3 PF06129.7 EGG42556.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus G3 protein T2SE PF00437.15 EGG42557.1 - 3.1e-13 49.2 0.0 6.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_1 PF00013.24 EGG42557.1 - 2.3e-09 36.7 0.1 1.9e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 EGG42557.1 - 3.9e-08 32.7 0.0 2.3e-07 30.2 0.0 2.4 1 0 0 1 1 1 1 KH domain AAA_14 PF13173.1 EGG42557.1 - 1.6e-06 28.0 0.0 3e-05 23.9 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EGG42557.1 - 2.2e-06 28.4 0.0 8.9e-06 26.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain KH_3 PF13014.1 EGG42557.1 - 7e-06 25.5 0.1 6.1e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 KH domain PIN_4 PF13638.1 EGG42557.1 - 1.6e-05 24.9 0.3 0.00014 21.9 0.2 2.5 1 1 0 1 1 1 1 PIN domain AAA_18 PF13238.1 EGG42557.1 - 2e-05 24.9 0.4 0.00026 21.3 0.0 3.0 4 0 0 4 4 4 1 AAA domain KH_5 PF13184.1 EGG42557.1 - 6.7e-05 22.6 1.9 0.00074 19.2 0.3 3.0 2 0 0 2 2 2 1 NusA-like KH domain AAA_22 PF13401.1 EGG42557.1 - 0.00033 20.7 0.1 0.0074 16.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EGG42557.1 - 0.0004 20.4 0.0 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain KH_4 PF13083.1 EGG42557.1 - 0.00046 19.7 0.1 0.0015 18.1 0.1 1.9 1 0 0 1 1 1 1 KH domain IstB_IS21 PF01695.12 EGG42557.1 - 0.00046 19.6 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGG42557.1 - 0.00068 19.0 0.0 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EGG42557.1 - 0.00078 18.3 0.0 0.0032 16.3 0.0 1.9 2 0 0 2 2 2 1 ArgK protein AAA_19 PF13245.1 EGG42557.1 - 0.00092 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EGG42557.1 - 0.0036 16.7 0.0 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EGG42557.1 - 0.004 17.4 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EGG42557.1 - 0.0051 16.7 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGG42557.1 - 0.0053 16.9 0.2 0.08 13.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGG42557.1 - 0.0083 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGG42557.1 - 0.012 15.1 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGG42557.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EGG42557.1 - 0.021 14.5 0.0 0.079 12.6 0.0 2.1 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 EGG42557.1 - 0.029 13.4 0.0 0.084 11.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DAP3 PF10236.4 EGG42557.1 - 0.031 13.1 0.0 0.46 9.3 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.5 EGG42557.1 - 0.036 13.2 0.0 0.085 12.0 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.7 EGG42557.1 - 0.037 13.6 0.0 0.098 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 EGG42557.1 - 0.037 13.5 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGG42557.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EGG42557.1 - 0.047 12.5 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 EGG42557.1 - 0.11 11.6 0.0 0.28 10.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Response_reg PF00072.19 EGG42558.1 - 3.7e-26 91.3 0.7 4.1e-26 91.1 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CoA_binding_2 PF13380.1 EGG42558.1 - 0.093 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Hpt PF01627.18 EGG42559.1 - 4.7e-06 26.5 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Syntaxin PF00804.20 EGG42559.1 - 0.0069 16.5 4.5 0.053 13.6 0.1 2.8 2 1 0 2 2 2 1 Syntaxin Tweety PF04906.8 EGG42559.1 - 0.023 13.1 0.6 0.025 13.0 0.4 1.1 1 0 0 1 1 1 0 Tweety Lip_prot_lig_C PF10437.4 EGG42559.1 - 0.025 14.2 0.3 0.05 13.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus DHC_N2 PF08393.8 EGG42559.1 - 0.029 12.8 2.3 0.39 9.1 0.1 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 2 Vps51 PF08700.6 EGG42559.1 - 0.042 13.6 0.5 0.042 13.6 0.3 2.5 3 0 0 3 3 3 0 Vps51/Vps67 Seryl_tRNA_N PF02403.17 EGG42559.1 - 0.056 13.4 2.4 0.058 13.4 0.2 1.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.7 EGG42559.1 - 0.064 13.0 1.0 0.11 12.3 0.7 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SMC_Nse1 PF07574.8 EGG42559.1 - 0.065 12.8 0.5 0.085 12.4 0.4 1.1 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex DUF3829 PF12889.2 EGG42559.1 - 0.068 12.3 0.9 0.079 12.1 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) KxDL PF10241.4 EGG42559.1 - 0.13 12.1 0.4 17 5.4 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein NPV_P10 PF05531.7 EGG42559.1 - 0.15 12.3 2.7 3.5 7.9 0.6 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EGG42559.1 - 0.2 10.8 2.7 0.23 10.6 1.5 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EGG42559.1 - 0.23 11.2 2.8 4.7 6.9 0.3 2.4 1 1 1 2 2 2 0 Laminin Domain II Snf7 PF03357.16 EGG42559.1 - 0.23 10.8 3.4 0.14 11.5 0.6 1.8 2 0 0 2 2 2 0 Snf7 F_actin_bind PF08919.5 EGG42559.1 - 0.25 11.0 1.9 14 5.4 0.2 2.3 2 1 0 2 2 2 0 F-actin binding MCPsignal PF00015.16 EGG42559.1 - 0.59 9.6 4.6 4.6 6.7 3.2 2.0 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FlaC_arch PF05377.6 EGG42559.1 - 0.62 10.0 5.7 15 5.5 1.4 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HATPase_c PF02518.21 EGG42560.1 - 3.4e-27 94.3 0.0 6.7e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG42560.1 - 8e-16 57.8 0.2 2e-15 56.5 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EGG42560.1 - 9.3e-09 35.3 0.2 4e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.1 EGG42560.1 - 1.9e-05 24.3 0.5 7e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG42560.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain UDG PF03167.14 EGG42561.1 - 3.3e-34 117.5 0.0 4.3e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Epimerase_2 PF02350.14 EGG42561.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pur_DNA_glyco PF02245.11 EGG42562.1 - 6.3e-65 217.7 0.0 6.9e-65 217.6 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) SNARE_assoc PF09335.6 EGG42563.1 - 2.7e-16 59.8 0.2 2.7e-16 59.8 0.2 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1418 PF07214.7 EGG42563.1 - 0.028 14.0 0.7 0.043 13.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF697 PF05128.7 EGG42563.1 - 0.032 13.7 0.1 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Glycophorin_A PF01102.13 EGG42563.1 - 0.038 13.7 0.7 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A MFS_1 PF07690.11 EGG42563.1 - 0.044 12.5 1.6 0.05 12.2 1.1 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily zf-DHHC PF01529.15 EGG42563.1 - 0.12 11.7 1.6 0.12 11.7 0.3 1.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase EF1_GNE PF00736.14 EGG42565.1 - 0.049 13.3 0.2 0.067 12.8 0.2 1.2 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain Memo PF01875.12 EGG42566.1 - 0.013 14.4 0.5 0.017 13.9 0.2 1.4 1 1 0 1 1 1 0 Memo-like protein DUF553 PF04473.7 EGG42566.1 - 0.044 13.0 0.3 0.044 13.0 0.2 1.5 2 0 0 2 2 2 0 Transglutaminase-like domain Prp18 PF02840.10 EGG42566.1 - 0.065 13.0 2.0 0.1 12.3 1.4 1.3 1 1 0 1 1 1 0 Prp18 domain DUF1884 PF08967.5 EGG42566.1 - 0.48 10.5 4.1 0.28 11.2 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1884) ArdA PF07275.6 EGG42566.1 - 0.66 10.2 8.1 0.77 9.9 5.6 1.1 1 0 0 1 1 1 0 Antirestriction protein (ArdA) ABC_tran PF00005.22 EGG42567.1 - 1.5e-25 90.0 0.0 2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 EGG42567.1 - 2.3e-18 66.2 0.3 3.8e-18 65.6 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 EGG42567.1 - 4.4e-11 43.2 1.7 3.6e-09 37.0 1.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGG42567.1 - 0.0011 18.4 1.1 0.073 12.5 0.0 2.2 1 1 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EGG42567.1 - 0.003 17.8 0.2 0.0078 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGG42567.1 - 0.0065 15.7 0.6 0.012 14.8 0.4 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EGG42567.1 - 0.015 13.7 0.1 3.3 6.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGG42567.1 - 0.062 12.6 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGG42567.1 - 0.062 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 EGG42567.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 EGG42567.1 - 0.094 11.7 0.3 0.17 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Glyoxalase PF00903.20 EGG42568.1 - 1.1e-14 54.4 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGG42568.1 - 5.7e-14 52.6 0.0 7.1e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGG42568.1 - 2.5e-08 33.8 0.0 7.6e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGG42568.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 Glyoxalase-like domain KH_5 PF13184.1 EGG42569.1 - 5.8e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NusA-like KH domain Ribosomal_S2 PF00318.15 EGG42569.1 - 0.0014 17.9 2.3 0.0014 17.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S2 tRNA-synt_2 PF00152.15 EGG42570.1 - 6.3e-89 298.0 0.1 9.6e-89 297.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGG42570.1 - 9e-12 44.6 1.0 1.7e-11 43.7 0.7 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGG42570.1 - 0.0043 16.2 0.2 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGG42570.1 - 0.094 12.2 0.4 0.65 9.5 0.1 2.2 2 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) P-II PF00543.17 EGG42572.1 - 0.0014 19.0 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.3 EGG42572.1 - 0.0091 15.9 0.0 0.031 14.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3240) DUF190 PF02641.10 EGG42572.1 - 0.034 13.9 0.4 0.052 13.4 0.3 1.3 1 1 0 1 1 1 0 Uncharacterized ACR, COG1993 Nit_Regul_Hom PF10126.4 EGG42572.1 - 0.038 13.7 0.3 0.074 12.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII MobB PF03205.9 EGG42572.1 - 0.069 12.8 0.2 0.14 11.8 0.1 1.5 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF897 PF05982.7 EGG42573.1 - 2e-92 309.5 20.6 2.3e-92 309.2 14.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF897) SseC PF04888.7 EGG42573.1 - 0.14 11.4 1.1 0.29 10.4 0.8 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4006 PF13179.1 EGG42573.1 - 0.58 9.7 4.1 5.2 6.6 1.5 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF1510 PF07423.6 EGG42574.1 - 0.00067 19.0 0.2 0.00077 18.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2839 PF10999.3 EGG42574.1 - 1.4 9.0 3.2 1.3 9.0 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) SnoaL_2 PF12680.2 EGG42576.1 - 1.2e-08 35.2 0.0 1.5e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EGG42576.1 - 0.00025 21.2 0.0 0.00029 20.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) LEH PF07858.7 EGG42576.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL PF07366.7 EGG42576.1 - 0.0038 16.8 0.0 0.009 15.6 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3593 PF12159.3 EGG42576.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) CybS PF05328.7 EGG42576.1 - 0.15 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 CybS Iso_dh PF00180.15 EGG42577.1 - 2.1e-101 339.3 0.3 2.4e-101 339.1 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 EGG42577.1 - 0.00062 19.0 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA HMGL-like PF00682.14 EGG42578.1 - 4.2e-76 255.7 0.5 7.7e-76 254.8 0.3 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EGG42578.1 - 1.5e-29 102.5 1.2 2.9e-29 101.5 0.8 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Glyco_hydro_97 PF10566.4 EGG42578.1 - 0.0036 16.4 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 DUF4147 PF13660.1 EGG42578.1 - 0.014 14.5 0.1 0.031 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) ALS_ss_C PF10369.4 EGG42579.1 - 2.3e-24 84.8 0.4 2.2e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.1 EGG42579.1 - 4.4e-17 61.6 0.0 1.1e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 EGG42579.1 - 3.3e-13 48.7 0.0 6.1e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EGG42579.1 - 0.00069 19.8 0.1 0.0016 18.7 0.1 1.7 1 0 0 1 1 1 1 ACT domain Acylphosphatase PF00708.13 EGG42579.1 - 0.057 13.5 0.2 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Acylphosphatase DUF2344 PF10105.4 EGG42579.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) TPP_enzyme_N PF02776.13 EGG42580.1 - 2.3e-61 206.2 0.4 3.1e-59 199.3 0.1 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGG42580.1 - 1.6e-47 160.8 0.3 3.1e-46 156.7 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGG42580.1 - 3.4e-45 153.1 0.1 8.5e-45 151.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain SnoaL_3 PF13474.1 EGG42581.1 - 6.4e-08 32.6 0.0 8.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.5 EGG42581.1 - 1.6e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association DUF4440 PF14534.1 EGG42581.1 - 0.0011 19.2 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Saccharop_dh_N PF04455.7 EGG42584.1 - 4e-37 126.4 0.3 8.7e-37 125.3 0.2 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region KaiC PF06745.8 EGG42585.1 - 6.7e-60 202.0 0.2 8.2e-60 201.7 0.1 1.0 1 0 0 1 1 1 1 KaiC GvpD PF07088.6 EGG42585.1 - 3.2e-13 48.8 0.0 4.2e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA_25 PF13481.1 EGG42585.1 - 1.1e-06 28.2 0.0 2.7e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EGG42585.1 - 3.5e-06 26.1 0.0 7.5e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EGG42585.1 - 0.00021 21.4 0.1 0.0034 17.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EGG42585.1 - 0.00031 21.0 0.2 0.00074 19.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGG42585.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 EGG42585.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein T2SE PF00437.15 EGG42585.1 - 0.0022 16.9 0.0 0.0044 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EGG42585.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGG42585.1 - 0.003 18.3 1.4 0.0076 17.0 0.9 1.8 1 1 0 1 1 1 1 AAA domain PPV_E1_C PF00519.12 EGG42585.1 - 0.0039 15.8 0.0 0.66 8.5 0.0 2.2 2 0 0 2 2 2 1 Papillomavirus helicase Arch_ATPase PF01637.13 EGG42585.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EGG42585.1 - 0.012 15.1 0.8 0.055 13.0 0.6 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGG42585.1 - 0.013 14.9 0.0 0.062 12.7 0.0 2.1 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EGG42585.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EGG42585.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EGG42585.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EGG42585.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.4 EGG42585.1 - 0.029 13.3 0.0 0.087 11.7 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EGG42585.1 - 0.031 13.2 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_31 PF13614.1 EGG42585.1 - 0.035 14.0 0.0 0.068 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 EGG42585.1 - 0.037 14.4 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal AAA_28 PF13521.1 EGG42585.1 - 0.046 13.6 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGG42585.1 - 0.063 12.7 0.0 0.18 11.3 0.0 1.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EGG42585.1 - 0.068 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EGG42585.1 - 0.068 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 EGG42585.1 - 0.078 12.4 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EGG42585.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EGG42585.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 NTPase TrmB PF01978.14 EGG42586.1 - 3.9e-11 42.4 0.0 8.2e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 EGG42586.1 - 0.005 16.3 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_9 PF08221.6 EGG42586.1 - 0.032 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_20 PF12840.2 EGG42586.1 - 0.039 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.2 EGG42586.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 MarR family Arc_PepC_II PF06847.6 EGG42587.1 - 1.3e-09 38.3 0.0 1.3e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 Archaeal Peptidase A24 C-terminus Type II Peptidase_A24 PF01478.13 EGG42587.1 - 6.2e-07 29.5 9.1 1.2e-06 28.6 6.3 1.5 1 0 0 1 1 1 1 Type IV leader peptidase family TrmB PF01978.14 EGG42588.1 - 1.9e-12 46.6 0.3 2.8e-12 46.1 0.2 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 EGG42588.1 - 0.0013 18.1 1.8 0.0036 16.6 0.3 2.1 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 EGG42588.1 - 0.0031 17.2 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain RNA_pol_Rpb5_C PF01191.14 EGG42588.1 - 0.0032 17.0 0.1 0.0079 15.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain Rrf2 PF02082.15 EGG42588.1 - 0.0032 17.5 0.1 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_9 PF08221.6 EGG42588.1 - 0.019 14.8 0.1 0.048 13.5 0.1 1.7 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2250 PF10007.4 EGG42588.1 - 0.021 14.7 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PadR PF03551.9 EGG42588.1 - 0.077 12.7 0.1 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_27 PF13463.1 EGG42588.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain AMP-binding PF00501.23 EGG42589.1 - 2.1e-82 276.7 0.0 2.5e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG42589.1 - 9.4e-15 55.3 0.0 1.8e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_4 PF13420.1 EGG42589.1 - 0.018 14.9 0.1 0.052 13.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ProRS-C_2 PF09181.5 EGG42590.1 - 0.0056 16.5 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal GatB_N PF02934.10 EGG42591.1 - 1.3e-80 270.3 0.0 2.2e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGG42591.1 - 1.8e-33 115.3 4.8 4.1e-33 114.1 3.3 1.6 1 0 0 1 1 1 1 GatB domain DUF2986 PF11661.3 EGG42591.1 - 2.6 8.4 6.7 2.4 8.5 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Amidase PF01425.16 EGG42592.1 - 3.7e-132 441.3 0.0 4.2e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Amidase tRNA-synt_2 PF00152.15 EGG42594.1 - 1.6e-85 286.8 1.5 4.7e-85 285.3 1.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGG42594.1 - 9.8e-12 44.5 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGG42594.1 - 0.0018 17.5 0.2 0.084 12.0 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) DUF1297 PF06973.7 EGG42597.1 - 1.4e-73 246.2 0.2 1.8e-73 245.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 EGG42597.1 - 1.1e-46 157.6 0.0 2e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) ATP-grasp_4 PF13535.1 EGG42597.1 - 0.0087 15.8 0.0 0.06 13.0 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain PEN-2 PF10251.4 EGG42598.1 - 0.068 13.3 0.5 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Papilloma_E5 PF03025.9 EGG42598.1 - 2.6 8.0 9.8 3.1 7.7 3.1 2.3 2 0 0 2 2 2 0 Papillomavirus E5 Hydantoinase_A PF01968.13 EGG42599.1 - 1.6e-57 194.8 3.4 1.6e-57 194.8 2.4 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGG42599.1 - 9e-24 83.9 9.4 2.6e-22 79.1 4.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EGG42599.1 - 2.2e-08 32.8 4.6 1.4e-05 23.6 0.8 2.6 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EGG42599.1 - 1.5e-06 27.6 1.5 2e-05 24.0 0.1 2.7 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.16 EGG42599.1 - 0.00012 21.4 1.0 0.00039 19.8 0.7 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FTR1 PF03239.9 EGG42600.1 - 8.8e-22 77.4 20.7 4.5e-15 55.3 3.8 2.4 1 1 1 2 2 2 2 Iron permease FTR1 family Pox_M2 PF04887.7 EGG42601.1 - 0.019 14.2 0.4 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 Poxvirus M2 protein RBD-FIP PF09457.5 EGG42601.1 - 0.045 13.5 1.3 0.092 12.5 0.1 2.1 2 0 0 2 2 2 0 FIP domain Ly49 PF08391.5 EGG42601.1 - 2.4 8.2 9.6 3.8 7.6 1.1 3.2 2 2 0 2 2 2 0 Ly49-like protein, N-terminal region HTH_20 PF12840.2 EGG42602.1 - 2.3e-05 24.1 0.0 3.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.7 EGG42602.1 - 3.5e-05 23.3 0.2 6.1e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.14 EGG42602.1 - 7.4e-05 22.3 0.1 0.00012 21.6 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Mga PF05043.8 EGG42602.1 - 0.00044 20.4 1.2 0.0012 19.1 0.5 1.9 1 1 1 2 2 2 1 Mga helix-turn-helix domain HTH_7 PF02796.10 EGG42602.1 - 0.00055 19.7 0.1 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_5 PF01022.15 EGG42602.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.5 EGG42602.1 - 0.0019 17.7 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_40 PF14493.1 EGG42602.1 - 0.0025 17.9 0.8 0.0036 17.4 0.4 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain FUR PF01475.14 EGG42602.1 - 0.0045 16.8 0.1 0.0064 16.4 0.1 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_23 PF13384.1 EGG42602.1 - 0.0049 16.4 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain DUF4423 PF14394.1 EGG42602.1 - 0.005 16.4 0.1 0.0058 16.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR_2 PF12802.2 EGG42602.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 MarR family DUF1492 PF07374.6 EGG42602.1 - 0.0096 16.0 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) Fe_dep_repress PF01325.14 EGG42602.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.1 EGG42602.1 - 0.021 14.9 0.2 0.036 14.1 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.1 EGG42602.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.7 EGG42602.1 - 0.033 13.6 0.1 0.063 12.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.1 EGG42602.1 - 0.035 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.17 EGG42602.1 - 0.052 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 EGG42602.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GerE PF00196.14 EGG42602.1 - 0.069 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family TFIIE_alpha PF02002.12 EGG42602.1 - 0.072 12.5 0.2 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit DUF2250 PF10007.4 EGG42602.1 - 0.12 12.2 0.2 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 EGG42603.1 - 0.0054 16.4 0.1 0.0067 16.1 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 EGG42603.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2250 PF10007.4 EGG42603.1 - 0.015 15.2 0.3 0.017 15.0 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PadR PF03551.9 EGG42603.1 - 0.057 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family FUR PF01475.14 EGG42603.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Ferric uptake regulator family Arch_flagellin PF01917.11 EGG42604.1 - 8.3e-17 61.4 12.8 1.1e-16 61.0 8.8 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin VCBS PF13517.1 EGG42604.1 - 0.081 13.2 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGG42604.1 - 0.54 10.0 2.6 4.2 7.1 0.7 2.5 1 1 1 2 2 2 0 FG-GAP repeat Arch_flagellin PF01917.11 EGG42605.1 - 9.5e-15 54.7 1.8 1.3e-14 54.2 1.3 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin DUF3494 PF11999.3 EGG42605.1 - 0.0054 16.3 0.5 0.01 15.4 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3494) Arch_flagellin PF01917.11 EGG42606.1 - 9.6e-21 74.2 6.9 1.1e-20 74.0 4.8 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin DUF1628 PF07790.6 EGG42606.1 - 0.9 10.3 5.6 2.9 8.7 3.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) Cupredoxin_1 PF13473.1 EGG42607.1 - 4.3e-05 23.3 0.0 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 Cupredoxin-like domain Copper-bind PF00127.15 EGG42607.1 - 0.00014 22.0 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Arch_flagellin PF01917.11 EGG42608.1 - 2.3e-20 73.0 5.2 3.2e-20 72.5 3.6 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin SLH PF00395.15 EGG42608.1 - 0.082 12.6 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 S-layer homology domain DUF1628 PF07790.6 EGG42608.1 - 2.2 9.0 7.8 1.6 9.5 3.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1628) TrmB PF01978.14 EGG42609.1 - 8.9e-15 54.1 0.0 2.4e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 EGG42609.1 - 2e-06 26.9 0.2 2.7e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_5 PF01022.15 EGG42609.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.7 EGG42609.1 - 0.014 14.9 0.0 0.052 13.2 0.0 2.0 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.1 EGG42609.1 - 0.024 14.0 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 EGG42609.1 - 0.039 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PNK3P PF08645.6 EGG42609.1 - 0.059 12.8 1.3 0.082 12.3 0.1 1.7 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Pup PF05639.6 EGG42609.1 - 0.086 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Pup-like protein TPR_11 PF13414.1 EGG42610.1 - 2.8e-52 174.2 23.9 1.1e-10 41.0 2.2 8.1 6 1 3 9 9 9 9 TPR repeat TPR_1 PF00515.23 EGG42610.1 - 3.9e-49 162.3 29.6 5.1e-08 32.2 0.9 12.9 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_2 PF07719.12 EGG42610.1 - 5.6e-49 160.1 12.0 3.9e-06 26.3 0.0 14.1 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 EGG42610.1 - 3.2e-43 145.5 0.0 2.6e-06 27.9 0.0 8.2 5 1 4 9 9 9 9 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42610.1 - 1.4e-41 140.6 2.7 5.5e-08 33.0 0.0 8.7 5 3 3 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42610.1 - 7.6e-36 119.2 41.9 2.1e-07 30.1 0.0 14.8 13 2 2 15 15 15 7 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42610.1 - 1.3e-32 109.2 0.0 0.0085 16.6 0.0 12.8 3 2 9 13 13 13 7 Tetratricopeptide repeat TPR_6 PF13174.1 EGG42610.1 - 1.4e-29 100.4 0.2 0.0087 16.4 0.0 13.4 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42610.1 - 4.7e-27 91.9 25.0 0.00028 20.8 0.0 11.3 13 0 0 13 13 11 6 Tetratricopeptide repeat Apc3 PF12895.2 EGG42610.1 - 8.7e-27 93.0 27.9 2.3e-06 27.6 0.0 7.4 3 3 6 9 9 9 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGG42610.1 - 3.6e-24 82.6 5.6 0.0049 16.5 0.0 11.2 11 1 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGG42610.1 - 5.3e-22 77.5 23.2 4.4e-05 23.3 0.0 9.2 2 2 10 12 12 12 7 Tetratricopeptide repeat TPR_9 PF13371.1 EGG42610.1 - 8e-18 64.0 0.0 0.014 15.1 0.0 7.2 3 2 6 9 9 9 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG42610.1 - 1e-09 38.1 12.3 0.57 10.1 0.0 8.3 7 1 1 9 9 9 3 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EGG42610.1 - 1.6e-09 37.7 4.9 0.081 13.0 0.0 7.0 4 2 3 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGG42610.1 - 7.6e-08 32.0 1.8 3.7 7.6 0.0 7.6 9 0 0 9 9 8 1 Tetratricopeptide repeat NARP1 PF12569.3 EGG42610.1 - 2.2e-06 26.7 19.5 0.0095 14.7 0.7 6.5 1 1 6 7 7 7 4 NMDA receptor-regulated protein 1 Coatomer_E PF04733.9 EGG42610.1 - 1.6e-05 24.2 14.6 0.28 10.3 1.9 4.5 2 1 2 4 4 4 3 Coatomer epsilon subunit Rapsyn_N PF10579.4 EGG42610.1 - 2.6e-05 23.9 0.0 4.8 7.0 0.0 5.6 5 0 0 5 5 5 1 Rapsyn N-terminal myristoylation and linker region TPR_21 PF09976.4 EGG42610.1 - 0.00013 21.9 1.9 6.6 6.6 0.0 4.7 3 1 2 5 5 4 0 Tetratricopeptide repeat DDT PF02791.12 EGG42610.1 - 0.0002 21.0 0.3 16 5.3 0.0 5.4 6 0 0 6 6 5 0 DDT domain TOM20_plant PF06552.7 EGG42610.1 - 0.001 18.7 1.6 3.9 7.0 0.0 4.0 3 1 1 4 4 4 2 Plant specific mitochondrial import receptor subunit TOM20 ChAPs PF09295.5 EGG42610.1 - 0.0022 16.7 10.5 0.14 10.8 0.4 4.0 1 1 2 4 4 4 3 ChAPs (Chs5p-Arf1p-binding proteins) SPOB_a PF14689.1 EGG42610.1 - 0.0051 16.3 2.0 8.6 6.0 0.0 5.1 7 0 0 7 7 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain MIT PF04212.13 EGG42610.1 - 4.1 7.3 15.7 13 5.7 0.1 6.6 7 1 1 8 8 8 0 MIT (microtubule interacting and transport) domain Peptidase_M10 PF00413.19 EGG42613.1 - 8.2e-09 35.3 0.0 8.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 EGG42613.1 - 8.1e-06 25.3 0.2 1.9e-05 24.0 0.1 1.5 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.1 EGG42613.1 - 0.01 15.8 0.2 0.02 14.9 0.1 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EGG42613.1 - 0.012 14.5 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 EGG42613.1 - 0.073 13.6 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Response_reg PF00072.19 EGG42614.1 - 1.1e-16 60.8 0.0 1.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain PAN_3 PF08277.7 EGG42615.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 PAN-like domain LysM PF01476.15 EGG42616.1 - 0.038 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 LysM domain CCDC142 PF14923.1 EGG42616.1 - 0.054 11.8 0.1 0.064 11.5 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil protein 142 HATPase_c PF02518.21 EGG42617.1 - 2.4e-20 72.3 0.2 5.3e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EGG42617.1 - 1.8e-19 70.0 0.1 5.1e-19 68.5 0.1 1.8 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 EGG42617.1 - 2.5e-12 46.6 0.3 5.5e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EGG42617.1 - 4.9e-09 35.9 0.1 1.5e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.1 EGG42617.1 - 6.7e-09 35.3 1.0 1.8e-08 33.9 0.7 1.7 1 0 0 1 1 1 1 GHKL domain PAS_4 PF08448.5 EGG42617.1 - 3.4e-08 33.4 0.0 5.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EGG42617.1 - 3.4e-08 33.4 0.2 6.2e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 EGG42617.1 - 1.5e-05 24.7 0.5 4e-05 23.2 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.1 EGG42617.1 - 0.0073 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain DUF848 PF05852.6 EGG42617.1 - 0.029 14.2 0.2 0.064 13.1 0.2 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) BLOC1_2 PF10046.4 EGG42617.1 - 0.16 12.0 2.6 0.23 11.5 0.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HATPase_c PF02518.21 EGG42618.1 - 1.2e-19 70.0 0.3 2.8e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG42618.1 - 8.9e-09 35.2 1.5 3.3e-08 33.4 0.4 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG42618.1 - 3e-08 33.2 0.9 3e-08 33.2 0.7 2.1 2 1 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.1 EGG42618.1 - 5.9e-05 22.7 0.1 0.00022 20.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG42618.1 - 0.026 14.3 0.0 0.09 12.5 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain YflT PF11181.3 EGG42618.1 - 2.9 8.0 10.1 0.51 10.5 3.5 2.3 2 1 0 2 2 2 0 Heat induced stress protein YflT MCPsignal PF00015.16 EGG42619.1 - 9.8e-19 67.7 8.7 2.2e-11 43.7 0.6 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain K-box PF01486.12 EGG42619.1 - 0.039 13.7 0.2 0.039 13.7 0.2 3.0 3 0 0 3 3 3 0 K-box region Ivy PF08816.6 EGG42619.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) Cob_adeno_trans PF01923.13 EGG42620.1 - 7.4e-57 191.6 0.0 8.5e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Lipase_GDSL PF00657.17 EGG42620.1 - 0.047 13.5 0.1 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Topoisom_I PF01028.15 EGG42620.1 - 0.12 11.4 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core HAS-barrel PF09378.5 EGG42620.1 - 0.13 12.2 0.3 2.5 8.0 0.1 2.7 2 1 1 3 3 3 0 HAS barrel domain HD_3 PF13023.1 EGG42621.1 - 1.4e-23 83.4 0.3 1.6e-23 83.2 0.2 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGG42621.1 - 0.0078 16.2 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 HD domain DUF4130 PF13566.1 EGG42621.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Med28 PF11594.3 EGG42622.1 - 0.036 14.3 0.9 0.045 13.9 0.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 DUF2543 PF10820.3 EGG42622.1 - 0.043 13.8 1.1 0.06 13.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) PMSR PF01625.16 EGG42622.1 - 0.097 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase RWD PF05773.17 EGG42623.1 - 0.023 14.5 0.6 0.03 14.2 0.4 1.2 1 0 0 1 1 1 0 RWD domain DUF1325 PF07039.6 EGG42623.1 - 0.039 13.5 0.7 0.046 13.3 0.5 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain SMC_Nse1 PF07574.8 EGG42623.1 - 0.053 13.1 1.0 0.06 12.9 0.7 1.1 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Hjc PF01870.13 EGG42624.1 - 0.00024 20.6 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) 3D PF06725.6 EGG42625.1 - 7e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 3D domain Methyltransf_18 PF12847.2 EGG42626.1 - 0.1 13.2 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF35_N PF12172.3 EGG42627.1 - 2.2e-05 24.2 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 EGG42627.1 - 0.083 12.7 1.3 0.15 11.9 0.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-UBR PF02207.15 EGG42627.1 - 0.086 12.5 0.9 0.11 12.1 0.7 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Thiolase_C PF02803.13 EGG42628.1 - 8.4e-13 47.8 0.9 1.9e-12 46.7 0.1 1.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 EGG42628.1 - 1.7e-05 23.9 0.0 4.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGG42628.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGG42628.1 - 0.0012 18.4 0.0 0.0036 16.9 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 EGG42628.1 - 0.026 14.3 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Dodecin PF07311.7 EGG42628.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Dodecin Bac_luciferase PF00296.15 EGG42629.1 - 1.5e-51 175.3 0.0 1.8e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF4649 PF15507.1 EGG42629.1 - 0.0099 15.6 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4649) NTP_transferase PF00483.18 EGG42630.1 - 4.4e-31 108.0 0.4 7e-31 107.3 0.3 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGG42630.1 - 1.8e-11 44.3 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGG42630.1 - 0.0035 16.8 0.0 0.0047 16.4 0.0 1.5 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Bgal_small_N PF02929.12 EGG42630.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.1 1 0 0 1 1 1 0 Beta galactosidase small chain CTP_transf_3 PF02348.14 EGG42630.1 - 0.065 12.8 0.3 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Cytidylyltransferase LpxK PF02606.9 EGG42630.1 - 0.089 11.7 0.0 0.6 8.9 0.0 1.9 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase SNARE_assoc PF09335.6 EGG42631.1 - 2.8e-21 76.0 1.3 2.8e-21 76.0 0.9 1.5 1 1 1 2 2 2 1 SNARE associated Golgi protein DUF1516 PF07457.6 EGG42632.1 - 0.044 13.8 5.1 0.073 13.1 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1516) DUF2085 PF09858.4 EGG42632.1 - 0.33 11.0 5.3 0.052 13.6 0.6 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF4418 PF14387.1 EGG42632.1 - 0.82 9.4 6.4 0.053 13.2 0.9 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) Sdh_cyt PF01127.17 EGG42632.1 - 1.8 8.3 6.4 3.4 7.5 1.1 2.0 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TarH PF02203.10 EGG42632.1 - 7.3 6.3 5.8 0.38 10.5 0.3 1.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue ATP-grasp PF02222.17 EGG42633.1 - 1.9e-58 196.6 0.0 2.9e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGG42633.1 - 1e-16 61.2 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG42633.1 - 1e-07 31.5 0.0 2.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGG42633.1 - 1.7e-05 23.7 0.0 0.00015 20.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGG42633.1 - 0.00013 21.8 0.1 0.00033 20.5 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EGG42633.1 - 0.00014 21.4 0.2 0.00054 19.4 0.1 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain 2-Hacid_dh_C PF02826.14 EGG42633.1 - 0.0037 16.4 0.0 0.0075 15.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGG42633.1 - 0.016 15.2 0.2 0.15 12.1 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain DUF1297 PF06973.7 EGG42633.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Pyr_redox PF00070.22 EGG42633.1 - 0.18 12.2 0.8 1.8 9.0 0.0 2.9 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 EGG42633.1 - 0.2 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family AIRC PF00731.15 EGG42634.1 - 9.8e-58 193.7 0.1 1.4e-57 193.2 0.1 1.2 1 0 0 1 1 1 1 AIR carboxylase DUF719 PF05334.8 EGG42634.1 - 0.034 14.1 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) PALP PF00291.20 EGG42635.1 - 3.9e-15 55.8 0.0 9.3e-15 54.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.20 EGG42635.1 - 4.2e-05 22.9 0.7 8.8e-05 21.8 0.1 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.1 EGG42635.1 - 6e-05 23.3 0.4 0.00011 22.4 0.3 1.3 1 0 0 1 1 1 1 ACT domain Thr_dehydrat_C PF00585.13 EGG42635.1 - 0.0039 16.7 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase PALP PF00291.20 EGG42636.1 - 2.8e-52 177.8 0.5 3.4e-52 177.5 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TetR_C_8 PF14278.1 EGG42637.1 - 4.5 7.7 8.5 3.8 7.9 0.2 2.8 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region Guanylate_cyc PF00211.15 EGG42638.1 - 7.3e-17 61.3 0.0 1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HALZ PF02183.13 EGG42639.1 - 0.0011 18.5 3.9 0.0025 17.4 2.7 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Mod_r PF07200.8 EGG42639.1 - 0.023 14.6 1.4 0.041 13.8 0.1 2.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 EGG42639.1 - 0.11 12.0 1.1 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF2205 PF10224.4 EGG42639.1 - 2.1 7.9 8.0 1.6 8.3 1.8 2.8 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) NYD-SP28_assoc PF14775.1 EGG42639.1 - 2.6 7.8 5.3 15 5.3 1.7 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Glyoxalase_2 PF12681.2 EGG42641.1 - 5.1e-15 55.9 0.0 6.4e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGG42641.1 - 4.4e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGG42641.1 - 0.0027 17.6 0.0 0.16 11.9 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AsnC_trans_reg PF01037.16 EGG42642.1 - 7.7e-07 28.7 0.0 9.3e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 AsnC family DUF2730 PF10805.3 EGG42642.1 - 0.0085 15.8 0.0 0.0099 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) ACT_4 PF13291.1 EGG42642.1 - 0.037 14.3 0.5 0.2 12.0 0.2 1.9 1 1 1 2 2 2 0 ACT domain GYD PF08734.6 EGG42642.1 - 0.12 12.1 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 GYD domain AsnC_trans_reg PF01037.16 EGG42643.1 - 0.0012 18.5 1.2 0.0014 18.2 0.8 1.2 1 0 0 1 1 1 1 AsnC family SipA PF09052.5 EGG42644.1 - 0.0069 14.8 0.5 0.0069 14.8 0.4 1.0 1 0 0 1 1 1 1 Salmonella invasion protein A CBFB_NFYA PF02045.10 EGG42644.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Protocadherin PF08374.6 EGG42644.1 - 0.94 9.0 4.7 1 8.9 3.3 1.0 1 0 0 1 1 1 0 Protocadherin HATPase_c PF02518.21 EGG42645.1 - 1.7e-19 69.5 0.3 3.4e-19 68.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG42645.1 - 2.9e-09 36.8 0.1 1.3e-07 31.5 0.0 2.6 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG42645.1 - 2.3e-07 30.4 0.1 5.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 EGG42645.1 - 0.00085 18.9 0.3 0.0024 17.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG42645.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain IL22 PF14565.1 EGG42645.1 - 0.14 12.1 1.8 0.36 10.9 1.3 1.6 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF948 PF06103.6 EGG42645.1 - 0.5 10.2 5.0 0.83 9.5 0.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Response_reg PF00072.19 EGG42648.1 - 3.3e-11 43.1 0.1 3.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox_2 PF07992.9 EGG42651.1 - 1.1e-14 54.8 0.0 2.6e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG42651.1 - 7.4e-08 32.6 0.4 3.2e-07 30.6 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG42651.1 - 0.03 14.3 0.0 0.51 10.3 0.0 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EST1_DNA_bind PF10373.4 EGG42652.1 - 0.0035 16.5 0.7 0.0041 16.3 0.5 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Cauli_AT PF03233.8 EGG42652.1 - 0.032 13.9 0.7 0.036 13.7 0.5 1.2 1 0 0 1 1 1 0 Aphid transmission protein Usp PF00582.21 EGG42653.1 - 4.4e-18 65.8 0.0 5.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Response_reg PF00072.19 EGG42654.1 - 7.5e-14 51.6 0.1 1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Cep57_MT_bd PF06657.8 EGG42654.1 - 0.045 13.7 0.2 0.045 13.7 0.1 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Suppressor_P21 PF11479.3 EGG42654.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA silencing suppressor P21 RNA_binding PF01877.12 EGG42654.1 - 0.058 13.3 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 RNA binding Response_reg PF00072.19 EGG42655.1 - 1.2e-22 80.0 0.1 1.5e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EGG42656.1 - 3.4e-20 71.8 0.0 8.4e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG42656.1 - 1.1e-08 34.9 0.0 2.5e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TarH PF02203.10 EGG42656.1 - 0.3 10.8 6.1 0.22 11.3 0.4 2.3 2 0 0 2 2 2 0 Tar ligand binding domain homologue Response_reg PF00072.19 EGG42657.1 - 6.3e-13 48.7 0.3 7.8e-13 48.4 0.2 1.1 1 0 0 1 1 1 1 Response regulator receiver domain P35 PF02331.10 EGG42657.1 - 0.057 12.5 0.6 0.068 12.2 0.4 1.2 1 0 0 1 1 1 0 Apoptosis preventing protein CRAL_TRIO_2 PF13716.1 EGG42657.1 - 0.13 12.1 0.3 0.95 9.3 0.2 2.0 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3267 PF11667.3 EGG42658.1 - 1.2 9.4 7.9 0.22 11.7 2.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3267) DUF334 PF03904.8 EGG42658.1 - 4.5 6.5 5.5 2.2 7.5 0.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF334) NHL PF01436.16 EGG42659.1 - 1.3e-15 56.4 2.0 0.11 12.4 0.0 7.3 6 1 0 6 6 6 4 NHL repeat Lactonase PF10282.4 EGG42659.1 - 2.5e-08 33.3 2.6 0.058 12.4 0.0 4.6 1 1 4 5 5 5 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 EGG42659.1 - 2.9e-05 22.5 5.3 0.023 13.0 0.3 2.9 1 1 1 3 3 3 3 Cytochrome D1 heme domain Arylesterase PF01731.15 EGG42659.1 - 3.3e-05 23.7 14.6 3.5 7.6 0.1 6.0 4 1 2 6 6 6 4 Arylesterase RhgB_N PF09284.5 EGG42659.1 - 0.022 14.1 2.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Rhamnogalacturonase B, N-terminal GDPD PF03009.12 EGG42659.1 - 0.064 12.7 0.0 0.18 11.3 0.0 1.7 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Response_reg PF00072.19 EGG42660.1 - 3.6e-26 91.3 0.7 4.4e-26 91.0 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.13 EGG42661.1 - 1.4e-51 174.5 0.2 1.7e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.10 EGG42661.1 - 3.9e-13 48.5 0.8 1.4e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, all-alpha domain Methyltransf_31 PF13847.1 EGG42661.1 - 2.3e-08 33.7 5.2 3.8e-06 26.5 2.4 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG42661.1 - 5e-08 33.3 0.4 5.1e-06 26.8 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG42661.1 - 3.4e-06 27.4 0.2 5.4e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG42661.1 - 8.1e-06 25.6 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG42661.1 - 2e-05 24.9 0.1 4.2e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG42661.1 - 0.00018 22.0 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGG42661.1 - 0.044 13.1 0.1 0.11 11.8 0.0 1.6 1 1 1 2 2 2 0 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EGG42661.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheD PF03975.8 EGG42662.1 - 9.1e-14 51.1 0.1 1.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Cu-oxidase_4 PF02578.10 EGG42662.1 - 0.074 12.1 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase CheC PF04509.7 EGG42663.1 - 6.5e-13 48.1 0.0 1.6e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 CheC-like family CheX PF13690.1 EGG42663.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX CheW PF01584.14 EGG42664.1 - 3.7e-21 75.0 0.0 4.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.18 EGG42665.1 - 2.6e-14 52.9 0.0 5.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Hpt domain H-kinase_dim PF02895.9 EGG42665.1 - 5.4e-11 42.6 0.5 1.7e-10 41.0 0.4 1.9 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c PF02518.21 EGG42665.1 - 6.4e-08 32.3 0.4 2e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGG42665.1 - 0.013 15.1 0.1 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF948 PF06103.6 EGG42665.1 - 0.015 15.1 1.2 11 5.9 0.0 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EGG42665.1 - 0.064 13.0 1.8 0.56 10.0 0.1 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Wzz PF02706.10 EGG42665.1 - 0.084 12.6 0.2 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Chain length determinant protein CheB_methylest PF01339.12 EGG42666.1 - 6.7e-64 214.6 0.0 1.2e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.19 EGG42666.1 - 6.9e-17 61.4 0.3 1.7e-16 60.2 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF3798 PF12683.2 EGG42666.1 - 0.059 12.4 0.5 0.098 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) DUF603 PF04645.7 EGG42667.1 - 0.004 17.1 2.2 0.0047 16.8 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF603 CDC37_N PF03234.9 EGG42667.1 - 1.5 9.1 5.3 3.2 8.0 3.6 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding CheW PF01584.14 EGG42668.1 - 2.3e-34 117.8 0.2 3.1e-34 117.4 0.2 1.1 1 0 0 1 1 1 1 CheW-like domain IZUMO PF15005.1 EGG42668.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion MCPsignal PF00015.16 EGG42669.1 - 2.6e-45 154.6 46.7 1.4e-43 148.9 19.5 2.6 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.1 EGG42669.1 - 7.3e-13 48.7 0.1 3.2e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EGG42669.1 - 1e-09 38.1 0.3 9e-09 35.1 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 EGG42669.1 - 1.4e-07 31.5 0.1 4.1e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 PAS fold Ferritin PF00210.19 EGG42669.1 - 0.016 14.9 1.3 0.062 13.0 0.3 2.6 1 1 1 2 2 2 0 Ferritin-like domain PAS_4 PF08448.5 EGG42669.1 - 0.039 13.9 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 PAS fold PhageMin_Tail PF10145.4 EGG42669.1 - 0.08 12.5 27.7 0.079 12.6 8.6 2.2 1 1 1 2 2 2 0 Phage-related minor tail protein HisKA PF00512.20 EGG42669.1 - 0.23 11.5 5.7 8.5 6.4 0.2 3.7 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain WXG100 PF06013.7 EGG42669.1 - 0.6 10.1 13.4 12 6.0 1.3 4.8 3 2 1 5 5 5 0 Proteins of 100 residues with WXG APG17 PF04108.7 EGG42669.1 - 1.2 7.8 20.5 2.7 6.6 3.2 3.1 1 1 2 3 3 3 0 Autophagy protein Apg17 Reo_sigmaC PF04582.7 EGG42669.1 - 1.4 8.0 28.3 1.1 8.3 4.6 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EGG42669.1 - 2.7 6.5 30.2 0.21 10.1 7.9 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.3 EGG42669.1 - 2.7 7.8 17.2 0.97 9.3 2.8 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 EGG42669.1 - 2.9 7.6 30.2 0.2 11.4 2.3 4.0 2 2 1 3 3 3 0 Laminin Domain II DUF3493 PF11998.3 EGG42670.1 - 0.031 14.1 0.2 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) T2SE PF00437.15 EGG42671.1 - 2.3e-45 154.6 0.0 3.2e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EGG42672.1 - 3.6e-19 68.7 0.5 4.3e-19 68.5 0.4 1.0 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EGG42672.1 - 3.7e-06 26.4 0.0 8.1e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EGG42672.1 - 0.00015 20.7 0.0 0.00024 20.0 0.0 1.4 1 0 0 1 1 1 1 Rad51 Arch_ATPase PF01637.13 EGG42672.1 - 0.00018 21.2 0.4 0.00025 20.8 0.3 1.1 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EGG42672.1 - 0.00024 20.8 0.1 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 NACHT domain PAXNEB PF05625.6 EGG42672.1 - 0.00046 19.1 3.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 2 PAXNEB protein DUF2075 PF09848.4 EGG42672.1 - 0.00079 18.5 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EGG42672.1 - 0.0029 17.4 1.5 0.037 13.9 1.1 2.2 1 1 0 1 1 1 1 AAA domain DUF835 PF05763.7 EGG42672.1 - 0.003 17.1 0.9 0.0047 16.4 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF835) AAA_22 PF13401.1 EGG42672.1 - 0.0046 17.1 0.0 0.0081 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGG42672.1 - 0.0047 16.4 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EGG42672.1 - 0.0068 16.7 0.3 0.031 14.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AF2331-like PF14556.1 EGG42672.1 - 0.037 14.3 0.1 0.093 13.0 0.1 1.7 1 0 0 1 1 1 0 AF2331-like NB-ARC PF00931.17 EGG42672.1 - 0.049 12.4 0.6 0.077 11.8 0.4 1.3 1 1 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EGG42672.1 - 0.05 13.3 0.8 0.55 9.9 0.6 2.1 1 1 0 1 1 1 0 NTPase AAA PF00004.24 EGG42672.1 - 0.071 13.3 0.7 0.14 12.3 0.5 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGG42672.1 - 0.091 12.9 0.2 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 RNA helicase Elong_Iki1 PF10483.4 EGG42672.1 - 0.1 11.9 1.4 0.15 11.4 0.6 1.4 1 1 0 1 1 1 0 Elongator subunit Iki1 FtsK_SpoIIIE PF01580.13 EGG42672.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF1011 PF06237.7 EGG42672.1 - 0.16 11.8 0.8 3.6 7.5 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1011) Arch_flagellin PF01917.11 EGG42674.1 - 1e-05 25.2 7.7 5e-05 23.0 5.4 1.8 1 1 0 1 1 1 1 Archaebacterial flagellin DUF1985 PF09331.6 EGG42675.1 - 0.059 13.1 0.1 0.063 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) CPSase_L_D3 PF02787.14 EGG42675.1 - 0.077 12.7 0.4 0.12 12.1 0.3 1.4 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF4352 PF11611.3 EGG42676.1 - 7.7e-12 45.4 2.0 9.9e-12 45.0 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) Aegerolysin PF06355.8 EGG42676.1 - 0.042 13.7 0.2 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 Aegerolysin MacB_PCD PF12704.2 EGG42676.1 - 0.047 13.2 0.7 0.06 12.9 0.5 1.2 1 0 0 1 1 1 0 MacB-like periplasmic core domain Rxt3 PF08642.5 EGG42677.1 - 0.062 13.5 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF2299 PF10061.4 EGG42678.1 - 7.2e-05 22.2 0.2 8.7e-05 21.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) DUF4257 PF14074.1 EGG42679.1 - 0.00091 18.8 0.1 0.0011 18.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) MASE2 PF05230.6 EGG42679.1 - 0.0024 17.8 0.1 0.0028 17.5 0.1 1.0 1 0 0 1 1 1 1 MASE2 domain Transgly_assoc PF04226.8 EGG42679.1 - 0.0076 16.3 1.8 0.011 15.7 1.3 1.3 1 0 0 1 1 1 1 Transglycosylase associated protein 5TM-5TMR_LYT PF07694.7 EGG42679.1 - 0.013 14.8 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF2407_C PF13373.1 EGG42679.1 - 0.017 15.0 0.2 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain Bac_Ubq_Cox PF01654.12 EGG42679.1 - 0.021 13.2 0.1 0.024 13.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase DUF1129 PF06570.6 EGG42679.1 - 0.023 14.0 0.1 0.023 14.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Cyto_ox_2 PF02322.10 EGG42679.1 - 0.026 13.6 0.0 0.027 13.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome oxidase subunit II Tic20 PF09685.5 EGG42679.1 - 0.028 14.3 0.2 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Tic20-like protein DUF3816 PF12822.2 EGG42679.1 - 0.036 13.9 0.4 0.039 13.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF3180 PF11377.3 EGG42679.1 - 0.081 12.7 0.2 0.097 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Choline_transpo PF04515.7 EGG42679.1 - 0.082 11.6 0.1 0.09 11.5 0.1 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter RseC_MucC PF04246.7 EGG42679.1 - 0.092 12.3 0.2 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.11 EGG42679.1 - 0.13 10.9 1.8 0.94 8.1 0.0 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily LHC PF00556.15 EGG42679.1 - 0.41 10.5 3.7 5 7.0 0.4 2.1 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Tad PF13400.1 EGG42679.1 - 1.3 9.0 3.8 3 7.9 0.1 2.0 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DZR PF12773.2 EGG42680.1 - 0.0017 18.1 0.2 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-IS66 PF13005.2 EGG42680.1 - 0.0077 16.1 0.4 0.97 9.4 0.1 2.5 2 0 0 2 2 2 1 zinc-finger binding domain of transposase IS66 C1_4 PF07975.7 EGG42680.1 - 0.022 14.7 0.1 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 EGG42680.1 - 0.025 14.5 0.4 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.21 EGG42680.1 - 0.036 14.4 1.0 0.5 10.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_ribbon_recom PF13408.1 EGG42680.1 - 0.048 13.9 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 EGG42680.1 - 0.059 12.8 2.1 1.7 8.1 0.3 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.7 EGG42680.1 - 0.068 12.5 1.9 1.8 8.0 0.2 2.3 2 0 0 2 2 2 0 HypF finger DUF35_N PF12172.3 EGG42680.1 - 0.086 12.7 2.0 3.1 7.8 0.2 2.2 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-LYAR PF08790.6 EGG42680.1 - 0.092 12.4 2.1 3.4 7.4 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Ribosomal_L6 PF00347.18 EGG42682.1 - 6.8e-09 36.1 6.1 3.7e-05 24.1 0.4 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 BON PF04972.12 EGG42682.1 - 0.008 15.9 4.9 3.3 7.5 0.0 3.8 4 1 0 4 4 4 2 BON domain S_layer_C PF05124.7 EGG42682.1 - 0.034 13.7 0.2 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region Ribosomal_S8 PF00410.14 EGG42683.1 - 5.6e-21 74.7 0.0 7.1e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.16 EGG42684.1 - 3e-15 55.3 2.8 3.4e-15 55.1 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.9 EGG42684.1 - 0.028 14.0 3.7 0.23 11.1 2.8 1.9 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS DUF2318 PF10080.4 EGG42684.1 - 0.087 12.6 0.2 0.091 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-AD PF07776.10 EGG42684.1 - 0.14 12.1 1.4 0.27 11.2 0.5 1.7 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) Ribosomal_L5_C PF00673.16 EGG42685.1 - 2.6e-23 81.5 0.0 4.2e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGG42685.1 - 2.2e-09 36.9 0.2 5.7e-09 35.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_S4e PF00900.15 EGG42686.1 - 1.8e-22 78.7 0.2 3.1e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EGG42686.1 - 1.2e-13 50.6 1.1 1.9e-13 49.9 0.8 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EGG42686.1 - 0.00037 19.8 0.1 0.00086 18.6 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EGG42686.1 - 0.0048 16.5 0.2 0.027 14.2 0.0 2.4 2 0 0 2 2 2 1 KOW motif KOW PF00467.24 EGG42687.1 - 6.5e-07 28.8 3.9 1.2e-06 27.9 0.7 2.4 2 1 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.9 EGG42687.1 - 0.025 13.6 0.4 0.038 13.0 0.1 1.4 1 1 0 1 1 1 0 RNA methyltransferase Ribosomal_L14 PF00238.14 EGG42688.1 - 8.2e-32 109.5 0.6 9.4e-32 109.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e EutN_CcmL PF03319.8 EGG42688.1 - 0.1 13.0 0.1 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome Ribosomal_S17 PF00366.15 EGG42689.1 - 6.8e-18 64.4 1.8 8.5e-18 64.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 UPF0086 PF01868.11 EGG42690.1 - 2.3e-24 84.8 0.2 2.5e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF4430 PF14478.1 EGG42690.1 - 0.029 14.4 0.7 0.039 13.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Ribosomal_L29 PF00831.18 EGG42691.1 - 1.5e-13 50.1 3.5 1.8e-13 49.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein IncA PF04156.9 EGG42691.1 - 0.043 13.4 1.0 0.048 13.2 0.7 1.1 1 0 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 EGG42691.1 - 0.051 13.7 0.4 0.055 13.6 0.3 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AcylCoA_dehyd_C PF12186.3 EGG42691.1 - 0.085 12.7 1.3 4.3 7.2 0.1 2.0 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Snapin_Pallidin PF14712.1 EGG42691.1 - 0.096 13.0 2.3 0.11 12.7 1.6 1.2 1 0 0 1 1 1 0 Snapin/Pallidin DUF1090 PF06476.7 EGG42691.1 - 0.19 11.4 1.4 0.2 11.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) TMF_DNA_bd PF12329.3 EGG42691.1 - 0.42 10.4 4.8 2.3 8.0 3.3 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Ribosomal_S3_C PF00189.15 EGG42692.1 - 1.6e-14 53.8 0.7 2.7e-14 53.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGG42692.1 - 6.4e-14 51.2 0.0 1.9e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 EGG42692.1 - 0.0082 15.7 0.7 0.049 13.2 0.1 2.4 3 0 0 3 3 3 1 KH domain KH_3 PF13014.1 EGG42692.1 - 0.056 13.1 1.5 0.14 11.8 0.5 2.1 2 0 0 2 2 2 0 KH domain AMIN PF11741.3 EGG42692.1 - 0.088 12.7 0.4 13 5.7 0.0 3.0 3 0 0 3 3 3 0 AMIN domain Ribosomal_L22 PF00237.14 EGG42693.1 - 5.6e-31 106.6 0.6 6.7e-31 106.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2791 PF10923.3 EGG42693.1 - 0.023 13.3 0.0 0.023 13.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Ribosomal_S19 PF00203.16 EGG42694.1 - 3.5e-24 84.2 0.1 5.4e-24 83.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L23 PF00276.15 EGG42695.1 - 2.1e-12 46.7 0.8 4.6e-12 45.7 0.6 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.14 EGG42695.1 - 0.018 14.5 0.1 0.025 14.0 0.0 1.3 1 1 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain RRM_5 PF13893.1 EGG42695.1 - 0.033 14.0 0.3 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG42695.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.17 EGG42696.1 - 2.7e-09 36.7 0.0 2.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L4 PF00573.17 EGG42697.1 - 2.6e-17 62.8 0.7 3e-17 62.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.17 EGG42698.1 - 2.1e-54 184.6 1.1 2.5e-54 184.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Methyltrn_RNA_3 PF02598.12 EGG42699.1 - 1.6e-51 175.3 0.0 2e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Proteasome PF00227.21 EGG42700.1 - 1.7e-52 177.5 0.3 2.1e-52 177.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGG42700.1 - 1.4e-14 53.0 0.6 5.1e-14 51.2 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF371 PF04027.8 EGG42701.1 - 6e-42 142.4 0.1 6.5e-42 142.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) WbqC PF08889.6 EGG42702.1 - 0.005 16.3 0.4 0.0066 15.9 0.3 1.2 1 0 0 1 1 1 1 WbqC-like protein family Snf7 PF03357.16 EGG42703.1 - 2.2e-07 30.4 3.5 3.5e-07 29.7 2.4 1.4 1 1 0 1 1 1 1 Snf7 Sulphotransf PF09037.5 EGG42703.1 - 0.054 12.9 0.1 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Stf0 sulphotransferase ELFV_dehydrog PF00208.16 EGG42703.1 - 0.086 12.4 1.6 0.14 11.7 1.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SH3_8 PF13457.1 EGG42703.1 - 0.089 12.9 0.4 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 SH3-like domain YkyA PF10368.4 EGG42703.1 - 0.093 12.0 3.5 0.13 11.5 2.5 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Fib_alpha PF08702.5 EGG42703.1 - 0.37 10.9 6.3 0.28 11.2 2.8 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Response_reg PF00072.19 EGG42704.1 - 3.2e-19 69.0 0.3 3.4e-19 68.8 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.14 EGG42704.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain Aminotran_1_2 PF00155.16 EGG42705.1 - 8.4e-56 189.4 0.0 9.9e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG42705.1 - 1.8e-05 24.0 0.0 3.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGG42705.1 - 0.00022 19.6 0.0 0.00038 18.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme BATS PF06968.8 EGG42706.1 - 7.7e-23 80.1 0.1 2.3e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EGG42706.1 - 5.7e-17 62.3 0.6 1.4e-16 61.0 0.2 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_3 PF00202.16 EGG42707.1 - 2.2e-87 293.0 0.1 2.6e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EGG42707.1 - 0.00046 19.4 0.0 0.00073 18.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase TPM PF04536.9 EGG42708.1 - 6.6e-11 42.1 0.0 1.6e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase NIF PF03031.13 EGG42708.1 - 0.036 13.7 0.1 1.9 8.1 0.1 2.1 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase RCR PF12273.3 EGG42708.1 - 0.72 10.4 4.1 0.74 10.3 1.8 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red LemA PF04011.7 EGG42709.1 - 1.8e-49 167.3 0.4 2e-49 167.2 0.3 1.0 1 0 0 1 1 1 1 LemA family DUF479 PF04336.7 EGG42709.1 - 0.0064 16.5 0.2 0.0087 16.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF479 YkyA PF10368.4 EGG42709.1 - 0.011 15.0 1.7 0.019 14.3 1.2 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Ribosomal_L36e PF01158.13 EGG42709.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L36e AAA_26 PF13500.1 EGG42710.1 - 3.2e-27 95.4 0.0 3.6e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EGG42710.1 - 0.0021 17.5 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.4 EGG42710.1 - 0.063 13.1 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 ParA/MinD ATPase like HMG_CoA_synt_C PF08540.5 EGG42712.1 - 2.8e-31 109.0 0.1 5.7e-31 108.0 0.0 1.4 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGG42712.1 - 9.4e-31 106.6 0.2 1.5e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Thioredoxin_4 PF13462.1 EGG42713.1 - 5.5e-35 120.7 0.0 7.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EGG42713.1 - 2.3e-17 63.2 0.1 2.9e-16 59.6 0.1 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EGG42713.1 - 3.7e-07 30.3 0.3 1.8e-06 28.1 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG42713.1 - 0.0045 17.0 0.4 2.6 8.2 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_5 PF13743.1 EGG42713.1 - 0.05 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Response_reg PF00072.19 EGG42714.1 - 1e-18 67.3 0.1 1.7e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HTH_24 PF13412.1 EGG42714.1 - 0.0066 15.8 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF965 PF06135.7 EGG42714.1 - 0.022 14.7 0.1 0.076 13.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) HTH_11 PF08279.7 EGG42714.1 - 0.054 13.1 0.2 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 HTH domain zf-C3HC4_3 PF13920.1 EGG42714.1 - 0.07 12.8 11.1 2.4 7.9 0.5 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FeoC PF09012.5 EGG42714.1 - 0.073 12.7 0.1 0.28 10.9 0.1 2.1 1 0 0 1 1 1 0 FeoC like transcriptional regulator zinc-ribbons_6 PF07191.7 EGG42714.1 - 0.097 12.4 16.0 0.34 10.7 2.5 3.1 1 1 2 3 3 3 0 zinc-ribbons DZR PF12773.2 EGG42714.1 - 0.13 12.0 16.3 0.4 10.5 2.0 3.1 1 1 1 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 EGG42714.1 - 0.31 10.7 11.9 2.5 7.8 0.2 3.8 2 1 1 3 3 3 0 Zinc finger found in FPG and IleRS HypA PF01155.14 EGG42714.1 - 0.38 10.4 17.4 0.72 9.5 0.4 3.5 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EGG42714.1 - 0.38 10.7 22.3 1.3 9.0 0.1 5.6 4 2 2 6 6 6 0 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 EGG42714.1 - 0.58 10.2 14.4 2.5 8.1 3.8 3.0 1 1 2 3 3 3 0 DnaJ central domain Spt4 PF06093.8 EGG42714.1 - 0.7 9.8 16.5 0.49 10.3 0.1 3.5 2 1 2 4 4 4 0 Spt4/RpoE2 zinc finger zf-Di19 PF05605.7 EGG42714.1 - 0.96 9.6 9.1 0.24 11.5 3.5 2.3 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding Polysacc_deac_1 PF01522.16 EGG42715.1 - 1.4e-17 63.4 0.0 3.9e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGG42715.1 - 1.1e-05 24.5 0.5 0.00018 20.5 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 57 DUF4480 PF13715.1 EGG42715.1 - 0.0056 16.7 5.4 0.17 11.9 0.9 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4480) Glyco_tranf_2_3 PF13641.1 EGG42716.1 - 1.2e-35 123.3 0.0 1.7e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGG42716.1 - 2e-34 118.6 0.1 3.5e-34 117.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EGG42716.1 - 1.4e-25 90.1 0.0 1.4e-25 90.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.4 EGG42716.1 - 2.6e-11 43.1 0.1 7e-11 41.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 EGG42716.1 - 3.9e-11 42.0 0.3 4.8e-07 28.5 0.0 3.1 2 1 1 3 3 3 2 Chitin synthase Glyco_transf_21 PF13506.1 EGG42716.1 - 1.7e-09 37.2 0.0 2.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 FemAB PF02388.11 EGG42716.1 - 0.016 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 FemAB family Glyco_tranf_2_4 PF13704.1 EGG42716.1 - 0.024 14.9 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 DapB_N PF01113.15 EGG42717.1 - 8.3e-05 22.4 0.0 0.00034 20.5 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.19 EGG42717.1 - 9.5e-05 22.4 0.0 0.0079 16.1 0.0 2.5 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGG42717.1 - 0.025 14.8 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EGG42717.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF21 PF01595.15 EGG42718.1 - 1.4e-53 180.8 1.7 2.1e-53 180.3 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CorC_HlyC PF03471.12 EGG42718.1 - 2e-18 65.9 0.6 2e-18 65.9 0.4 2.1 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.23 EGG42718.1 - 3.2e-16 58.8 0.6 3.2e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain PALP PF00291.20 EGG42719.1 - 3.7e-43 147.9 0.0 4.9e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PK_C PF02887.11 EGG42719.1 - 0.36 10.3 1.8 0.88 9.1 0.3 2.1 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain KilA-N PF04383.8 EGG42720.1 - 0.056 13.0 0.8 0.08 12.5 0.5 1.3 1 0 0 1 1 1 0 KilA-N domain DUF4441 PF14536.1 EGG42720.1 - 0.097 12.6 8.3 0.17 11.8 5.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) Sec5 PF15469.1 EGG42721.1 - 0.0062 16.2 0.6 0.021 14.5 0.4 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 IFT20 PF14931.1 EGG42721.1 - 0.037 13.9 2.2 0.66 9.8 0.1 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2383 PF09537.5 EGG42721.1 - 0.054 13.7 0.2 2.4 8.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) AIRS_C PF02769.17 EGG42722.1 - 8.5e-16 58.3 0.0 1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GATase_2 PF00310.16 EGG42723.1 - 1.5e-21 76.5 0.0 2.4e-14 52.8 0.0 3.1 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGG42723.1 - 4.5e-16 59.0 0.0 2e-15 56.9 0.0 2.0 3 0 0 3 3 3 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGG42723.1 - 9.2e-14 51.2 0.0 1.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EGG42723.1 - 3.1e-13 49.5 0.0 8.3e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EGG42723.1 - 8.9e-07 27.8 0.0 2.6e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PRTase_3 PF15610.1 EGG42723.1 - 0.034 13.0 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 PRTase ComF-like Pribosyltran_N PF13793.1 EGG42723.1 - 0.061 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase AsnC_trans_reg PF01037.16 EGG42724.1 - 1.1e-09 37.8 0.8 1.2e-09 37.7 0.5 1.1 1 0 0 1 1 1 1 AsnC family PRANC PF09372.5 EGG42724.1 - 0.0008 19.3 0.0 0.00096 19.0 0.0 1.0 1 0 0 1 1 1 1 PRANC domain DUF427 PF04248.7 EGG42725.1 - 1.3e-29 101.6 0.4 1.4e-29 101.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.11 EGG42726.1 - 0.0075 15.0 3.7 0.0075 15.0 2.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Tic20 PF09685.5 EGG42726.1 - 0.018 14.9 5.4 0.025 14.5 3.7 1.2 1 0 0 1 1 1 0 Tic20-like protein Baculo_11_kDa PF06143.6 EGG42726.1 - 0.022 14.1 4.1 0.022 14.1 2.9 1.5 1 1 1 2 2 2 0 Baculovirus 11 kDa family DUF2207 PF09972.4 EGG42726.1 - 0.027 13.0 6.2 0.03 12.9 4.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Arteri_Gl PF00951.13 EGG42726.1 - 0.031 13.8 3.5 0.036 13.6 2.4 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein UPF0104 PF03706.8 EGG42726.1 - 0.034 13.4 3.8 0.037 13.3 2.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF2422 PF10337.4 EGG42726.1 - 0.035 12.9 2.1 0.037 12.8 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Claudin_2 PF13903.1 EGG42726.1 - 0.085 12.5 2.3 0.085 12.5 1.6 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NfeD PF01957.13 EGG42726.1 - 0.15 12.1 2.9 0.15 12.1 2.0 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding OSTMP1 PF09777.4 EGG42726.1 - 0.28 10.3 1.7 0.17 11.0 0.3 1.3 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor COPI_assoc PF08507.5 EGG42726.1 - 0.29 10.8 5.7 0.18 11.5 2.8 1.5 1 1 0 1 1 1 0 COPI associated protein DUF1469 PF07332.6 EGG42726.1 - 0.31 10.7 4.4 0.42 10.3 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF2721 PF11026.3 EGG42726.1 - 0.35 10.4 5.9 0.48 10.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) YrhC PF14143.1 EGG42726.1 - 0.36 10.8 5.3 0.62 10.0 3.7 1.4 1 1 0 1 1 1 0 YrhC-like protein VIT1 PF01988.14 EGG42726.1 - 0.65 9.4 6.8 0.67 9.4 4.7 1.1 1 0 0 1 1 1 0 VIT family DUF872 PF05915.7 EGG42726.1 - 0.96 9.3 4.9 0.28 11.0 0.2 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF973 PF06157.6 EGG42726.1 - 1.3 7.9 6.1 1.4 7.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) SieB PF14163.1 EGG42726.1 - 2.3 7.7 4.8 2.9 7.4 3.3 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B SdpI PF13630.1 EGG42726.1 - 3.7 7.3 13.7 5.7 6.7 9.5 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family ATP-synt_8 PF00895.15 EGG42726.1 - 5.1 7.3 6.1 7.2 6.8 0.2 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3487 PF11990.3 EGG42726.1 - 6.1 6.2 6.5 7.7 5.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF3185 PF11381.3 EGG42726.1 - 7.7 6.3 8.6 4.1 7.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF4363 PF14276.1 EGG42726.1 - 7.9 6.2 6.4 0.44 10.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Pentapeptide PF00805.17 EGG42727.1 - 1.9e-44 148.2 37.0 1.5e-12 46.4 1.8 4.9 1 1 5 6 6 6 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EGG42727.1 - 2.3e-19 68.9 0.1 1.2e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EGG42727.1 - 2.6e-15 56.0 0.6 2.3e-05 24.2 0.1 4.2 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) zf-ribbon_3 PF13248.1 EGG42728.1 - 0.0004 19.4 3.4 0.011 14.8 0.5 2.4 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2HC_2 PF13913.1 EGG42728.1 - 0.0095 15.5 7.0 0.58 9.8 0.8 2.7 2 0 0 2 2 2 2 zinc-finger of a C2HC-type DZR PF12773.2 EGG42728.1 - 0.015 15.0 7.3 0.45 10.3 0.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon Ecl1 PF12855.2 EGG42728.1 - 0.018 14.3 2.1 0.018 14.3 1.5 1.8 3 0 0 3 3 3 0 Life-span regulatory factor zinc_ribbon_4 PF13717.1 EGG42728.1 - 0.12 12.0 3.6 0.45 10.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG42728.1 - 0.14 11.7 3.6 0.42 10.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGG42728.1 - 0.24 10.9 6.7 1.4 8.5 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EGG42728.1 - 0.33 10.6 4.9 6.3 6.5 0.5 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Sgf11 PF08209.6 EGG42728.1 - 0.46 9.8 4.7 7.6 5.9 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) RIG-I_C-RD PF11648.3 EGG42728.1 - 0.53 10.1 6.3 0.86 9.4 4.4 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I PHD PF00628.24 EGG42728.1 - 0.57 9.9 6.6 5.5 6.7 0.5 2.2 2 0 0 2 2 2 0 PHD-finger DUF2688 PF10892.3 EGG42728.1 - 0.7 9.6 3.2 8.1 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) ADK_lid PF05191.9 EGG42728.1 - 0.87 9.3 8.3 3.5 7.3 1.2 3.0 2 1 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.1 EGG42728.1 - 1.1 9.0 5.3 3.4 7.4 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-MYND PF01753.13 EGG42728.1 - 1.6 8.6 8.8 0.96 9.3 1.5 2.3 2 0 0 2 2 2 0 MYND finger C1_1 PF00130.17 EGG42728.1 - 1.9 8.2 9.0 0.36 10.5 1.2 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L37e PF01907.14 EGG42728.1 - 2.3 8.0 7.0 0.38 10.6 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L37e HypA PF01155.14 EGG42728.1 - 3.4 7.3 6.8 56 3.4 4.7 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2116 PF09889.4 EGG42728.1 - 3.5 7.4 4.9 1.3 8.8 0.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-CCHC PF00098.18 EGG42728.1 - 4.4 7.4 8.4 11 6.1 0.2 2.9 3 0 0 3 3 3 0 Zinc knuckle NOB1_Zn_bind PF08772.6 EGG42728.1 - 7 6.5 10.5 11 5.9 2.6 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cript PF10235.4 EGG42728.1 - 8.5 6.8 12.2 1 9.7 2.7 2.1 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DUF2393 PF09624.5 EGG42729.1 - 0.23 11.0 1.7 0.3 10.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) SAICAR_synt PF01259.13 EGG42730.1 - 1.2e-38 132.6 0.0 1.5e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase HTH_20 PF12840.2 EGG42731.1 - 1.8e-09 37.2 0.1 3.1e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.15 EGG42731.1 - 2.7e-07 30.1 0.4 2.2e-06 27.2 0.3 2.2 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.5 EGG42731.1 - 1.1e-06 28.2 0.3 2.4e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain FUR PF01475.14 EGG42731.1 - 0.00012 22.0 0.4 0.00026 20.8 0.3 1.7 1 1 0 1 1 1 1 Ferric uptake regulator family HTH_11 PF08279.7 EGG42731.1 - 0.017 14.7 0.8 0.23 11.1 0.6 2.3 1 1 0 1 1 1 0 HTH domain Replic_Relax PF13814.1 EGG42731.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation HTH_24 PF13412.1 EGG42731.1 - 0.031 13.6 1.2 0.048 13.0 0.1 2.0 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HU-DNA_bdg PF14848.1 EGG42731.1 - 0.033 13.9 0.7 0.093 12.4 0.3 1.8 1 1 1 2 2 2 0 DNA-binding domain IKI3 PF04762.7 EGG42731.1 - 0.044 11.5 0.0 0.062 11.1 0.0 1.2 1 0 0 1 1 1 0 IKI3 family BAF PF02961.9 EGG42731.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Barrier to autointegration factor Pyridox_oxidase PF01243.15 EGG42732.1 - 1.4e-15 57.0 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EGG42732.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1027 PF06265.6 EGG42732.1 - 0.066 13.0 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1027) GATase_5 PF13507.1 EGG42733.1 - 1.1e-37 129.3 0.0 3.3e-37 127.7 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EGG42733.1 - 2.4e-09 36.9 0.0 3.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGG42733.1 - 2.6e-09 36.8 0.1 1.9e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 EGG42733.1 - 8.7e-07 28.5 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGG42733.1 - 1e-05 24.8 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_C26 PF07722.8 EGG42733.1 - 0.00058 19.3 0.1 0.0014 18.1 0.1 1.6 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.14 EGG42733.1 - 0.035 13.7 0.0 0.099 12.2 0.0 1.7 2 0 0 2 2 2 0 SNO glutamine amidotransferase family MscL PF01741.13 EGG42736.1 - 1.6e-20 73.5 4.6 1.9e-20 73.2 3.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Plasmodium_Vir PF05795.6 EGG42736.1 - 0.0035 16.6 0.3 0.0039 16.4 0.2 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Reticulon PF02453.12 EGG42736.1 - 0.024 14.2 0.4 0.034 13.7 0.3 1.3 1 0 0 1 1 1 0 Reticulon FtsX PF02687.16 EGG42736.1 - 0.098 12.4 5.3 0.14 11.9 3.6 1.2 1 0 0 1 1 1 0 FtsX-like permease family Glycoprotein_B PF00606.13 EGG42736.1 - 0.22 9.5 1.5 0.32 8.9 0.3 1.7 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B Colicin_V PF02674.11 EGG42736.1 - 0.37 10.6 8.2 0.68 9.7 5.7 1.4 1 1 0 1 1 1 0 Colicin V production protein TM_helix PF05552.7 EGG42736.1 - 0.37 10.4 4.0 4.6 6.9 0.3 2.3 2 0 0 2 2 2 0 Conserved TM helix Apq12 PF12716.2 EGG42736.1 - 6.6 6.5 10.3 0.34 10.6 2.9 1.9 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis AsnC_trans_reg PF01037.16 EGG42737.1 - 1.9e-10 40.2 0.1 2.2e-10 40.0 0.1 1.0 1 0 0 1 1 1 1 AsnC family UBN2 PF14223.1 EGG42738.1 - 0.08 12.7 0.4 0.085 12.6 0.3 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Phi-29_GP3 PF05435.6 EGG42738.1 - 0.088 12.0 0.1 0.092 11.9 0.1 1.1 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 DUF202 PF02656.10 EGG42741.1 - 0.025 14.7 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Tic20 PF09685.5 EGG42741.1 - 0.026 14.4 1.8 0.038 13.9 1.2 1.3 1 1 0 1 1 1 0 Tic20-like protein DUF4064 PF13273.1 EGG42741.1 - 0.026 14.6 1.1 0.037 14.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3671 PF12420.3 EGG42741.1 - 0.047 13.6 2.0 0.061 13.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function 7tm_4 PF13853.1 EGG42741.1 - 0.075 12.8 0.8 0.099 12.4 0.5 1.2 1 0 0 1 1 1 0 Olfactory receptor YfkB PF08756.5 EGG42741.1 - 0.096 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 YfkB-like domain 7TMR-DISM_7TM PF07695.6 EGG42741.1 - 0.14 11.7 3.0 5.1 6.7 0.1 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling Tetraspannin PF00335.15 EGG42741.1 - 0.23 10.7 6.5 1.2 8.4 0.2 2.0 1 1 1 2 2 2 0 Tetraspanin family DUF4097 PF13349.1 EGG42741.1 - 0.28 10.7 2.8 2.1 7.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4097) DUF3185 PF11381.3 EGG42741.1 - 0.64 9.8 7.6 1.7 8.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Myelin_PLP PF01275.14 EGG42741.1 - 0.65 9.2 3.3 0.8 8.9 2.3 1.0 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) DUF1206 PF06724.6 EGG42741.1 - 6.4 6.6 9.3 0.81 9.4 0.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) SP_C-Propep PF08999.5 EGG42741.1 - 6.5 6.3 7.5 1.3 8.6 0.5 2.0 1 1 1 2 2 2 0 Surfactant protein C, N terminal propeptide Polyketide_cyc2 PF10604.4 EGG42742.1 - 9.6e-14 51.7 0.0 1.1e-13 51.5 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport APG6 PF04111.7 EGG42743.1 - 2e-05 23.7 30.3 0.0042 16.1 11.8 2.3 2 0 0 2 2 2 2 Autophagy protein Apg6 AAA_13 PF13166.1 EGG42743.1 - 8.2e-05 21.2 43.5 0.00056 18.5 13.1 2.1 1 1 1 2 2 2 2 AAA domain CENP-F_leu_zip PF10473.4 EGG42743.1 - 0.00034 20.4 36.0 0.00081 19.2 3.9 3.5 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EGG42743.1 - 0.0037 16.4 7.8 0.0037 16.4 5.4 3.1 2 1 0 3 3 3 2 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 EGG42743.1 - 0.016 15.0 1.8 0.016 15.0 1.3 5.2 1 1 5 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus RBD-FIP PF09457.5 EGG42743.1 - 0.026 14.3 2.1 0.026 14.3 1.4 2.9 3 0 0 3 3 2 0 FIP domain IncA PF04156.9 EGG42743.1 - 0.034 13.7 39.2 0.2 11.2 13.6 3.6 2 1 1 3 3 3 0 IncA protein DUF1687 PF07955.6 EGG42743.1 - 0.063 13.2 11.2 0.061 13.2 3.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1687) Filament PF00038.16 EGG42743.1 - 0.19 11.1 27.2 0.13 11.7 3.1 2.8 1 1 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 EGG42743.1 - 0.2 10.3 42.2 0.012 14.3 9.8 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein PilJ PF13675.1 EGG42743.1 - 0.27 11.5 5.1 10 6.4 0.6 3.1 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4349 PF14257.1 EGG42743.1 - 0.39 9.9 6.4 7 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) CSTF2_hinge PF14327.1 EGG42743.1 - 0.59 10.2 9.1 0.2 11.7 0.9 3.3 2 1 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 NPV_P10 PF05531.7 EGG42743.1 - 0.77 10.0 38.5 0.8 10.0 1.3 6.3 3 3 3 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 EGG42743.1 - 0.9 7.8 36.9 0.017 13.5 8.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF342) MCPsignal PF00015.16 EGG42743.1 - 1 8.8 24.5 0.27 10.7 1.2 3.3 2 1 2 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 EGG42743.1 - 1.1 8.4 24.8 0.25 10.4 2.2 3.1 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Mod_r PF07200.8 EGG42743.1 - 1.3 8.9 28.9 0.091 12.6 8.8 3.7 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein UPF0449 PF15136.1 EGG42743.1 - 1.3 9.2 16.7 0.038 14.1 1.5 3.7 2 2 2 4 4 4 0 Uncharacterised protein family UPF0449 DUF4351 PF14261.1 EGG42743.1 - 1.4 8.8 12.2 8.7 6.2 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4351) Snapin_Pallidin PF14712.1 EGG42743.1 - 1.9 8.8 34.0 0.06 13.6 3.8 4.5 3 1 1 5 5 5 0 Snapin/Pallidin Tropomyosin_1 PF12718.2 EGG42743.1 - 2.9 7.7 29.5 0.59 9.9 7.9 3.6 2 1 1 3 3 3 0 Tropomyosin like RraB PF06877.6 EGG42743.1 - 3 8.5 8.0 0.83 10.3 1.5 3.0 2 1 1 3 3 3 0 Regulator of ribonuclease activity B Cep57_CLD_2 PF14197.1 EGG42743.1 - 4.3 7.3 11.6 0.92 9.4 1.0 3.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 BLOC1_2 PF10046.4 EGG42743.1 - 5.8 7.1 39.5 1.6 8.8 7.3 5.1 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prok-JAB PF14464.1 EGG42744.1 - 2.4e-13 49.5 0.0 3.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.16 EGG42744.1 - 0.0018 17.9 0.0 0.019 14.7 0.0 2.0 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-NADH-PPase PF09297.6 EGG42745.1 - 0.0019 17.6 2.7 0.028 13.9 0.5 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Peptidase_C74 PF12387.3 EGG42745.1 - 0.048 12.8 1.4 0.063 12.4 1.0 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase zf-C3HC4_3 PF13920.1 EGG42745.1 - 0.13 11.9 1.4 0.18 11.4 1.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 EGG42745.1 - 0.22 10.8 2.2 0.79 9.0 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 EGG42745.1 - 0.39 11.0 5.5 3.6 7.9 3.8 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 EGG42745.1 - 0.6 10.1 4.3 3.1 7.8 3.0 1.9 1 1 0 1 1 1 0 Zinc ribbon domain TFIIS_C PF01096.13 EGG42745.1 - 0.61 9.7 3.3 14 5.4 0.3 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-HIT PF04438.11 EGG42745.1 - 1 9.0 4.9 2.2 8.0 3.4 1.5 1 1 0 1 1 1 0 HIT zinc finger Zn_Tnp_IS1595 PF12760.2 EGG42745.1 - 1.8 8.4 4.7 2.2 8.1 0.8 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Lectin_C PF00059.16 EGG42746.1 - 0.25 12.0 1.6 0.77 10.4 1.1 1.8 1 1 0 1 1 1 0 Lectin C-type domain BPD_transp_1 PF00528.17 EGG42747.1 - 4.7e-27 94.6 9.1 4.7e-27 94.6 6.3 2.3 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.2 EGG42747.1 - 0.00031 20.0 2.1 0.00059 19.1 0.4 2.2 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.17 EGG42748.1 - 1.6e-37 128.8 17.7 1.6e-37 128.8 12.3 1.8 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component HN PF00423.14 EGG42748.1 - 0.12 10.5 0.7 0.16 10.2 0.5 1.3 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Ndc1_Nup PF09531.5 EGG42748.1 - 0.32 9.3 5.3 0.56 8.5 3.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GDPD_2 PF13653.1 EGG42749.1 - 0.0054 16.8 0.7 0.4 10.9 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DUF3290 PF11694.3 EGG42750.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) CarboxypepD_reg PF13620.1 EGG42751.1 - 4.4e-08 33.0 1.3 9.1e-08 32.0 0.9 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EGG42751.1 - 8.5e-07 28.9 6.4 1.3e-06 28.4 2.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) Big_1 PF02369.11 EGG42751.1 - 0.00022 21.0 0.9 0.00068 19.5 0.6 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Snapin_Pallidin PF14712.1 EGG42751.1 - 0.15 12.3 2.0 0.69 10.2 0.0 2.4 1 1 1 2 2 2 0 Snapin/Pallidin DUF3450 PF11932.3 EGG42751.1 - 0.51 9.5 4.3 0.37 10.0 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1972 PF09314.6 EGG42752.1 - 0.032 13.6 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) FlgD_ig PF13860.1 EGG42752.1 - 0.032 13.9 0.6 1.6 8.5 0.2 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain SNF2_N PF00176.18 EGG42754.1 - 2.9e-39 134.6 0.1 4.2e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG42754.1 - 2.6e-09 36.7 0.0 7.1e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG42754.1 - 7.1e-08 32.4 2.4 9.3e-08 32.1 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGG42754.1 - 9.1e-08 31.7 0.0 3.2e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HTH_5 PF01022.15 EGG42755.1 - 0.0067 16.0 1.5 0.021 14.4 0.3 2.4 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.1 EGG42755.1 - 0.015 15.6 0.2 0.056 13.7 0.0 2.2 2 1 0 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.14 EGG42755.1 - 0.018 14.7 1.7 0.093 12.4 0.1 2.6 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 EGG42755.1 - 0.027 14.5 0.2 0.075 13.0 0.1 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.1 EGG42755.1 - 0.036 13.4 0.3 1.3 8.4 0.2 3.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MRP-L20 PF12824.2 EGG42755.1 - 0.041 13.8 1.7 0.057 13.3 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Fe_dep_repress PF01325.14 EGG42755.1 - 0.042 13.7 0.5 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.2 EGG42755.1 - 0.052 13.3 0.1 0.54 10.1 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain DUF1136 PF06582.7 EGG42755.1 - 0.09 12.4 0.4 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) HSP20 PF00011.16 EGG42756.1 - 4.1e-23 81.1 2.1 5.3e-23 80.8 1.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EGG42756.1 - 6.6e-05 23.3 1.9 0.00016 22.1 1.3 1.6 1 1 0 1 1 1 1 CS domain OsmC PF02566.14 EGG42757.1 - 2.4e-17 62.9 0.0 4.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein Sod_Fe_N PF00081.17 EGG42758.1 - 1.8e-20 72.9 0.2 1.9e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EGG42759.1 - 8.7e-32 109.1 2.4 1e-31 108.9 1.7 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain HTH_24 PF13412.1 EGG42760.1 - 0.036 13.4 0.3 0.076 12.4 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.15 EGG42760.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TBP PF00352.16 EGG42761.1 - 6.7e-61 201.6 0.0 8e-30 102.0 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGG42761.1 - 1.5e-06 28.1 0.0 0.006 16.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Synuclein PF01387.12 EGG42761.1 - 0.1 12.4 2.7 0.18 11.7 0.6 2.0 2 0 0 2 2 2 0 Synuclein SHOCT PF09851.4 EGG42762.1 - 1.2e-11 43.6 0.8 2e-11 42.9 0.6 1.4 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.7 EGG42762.1 - 0.0082 15.9 0.6 0.016 14.9 0.1 1.7 1 1 1 2 2 2 1 Gas vesicle protein G TauE PF01925.14 EGG42762.1 - 0.032 13.6 0.0 0.033 13.6 0.0 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE TraX PF05857.6 EGG42762.1 - 0.032 13.8 0.1 0.037 13.6 0.1 1.1 1 0 0 1 1 1 0 TraX protein Halogen_Hydrol PF10112.4 EGG42762.1 - 0.055 12.8 0.1 0.065 12.6 0.1 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein FAD_binding_4 PF01565.18 EGG42763.1 - 5e-33 113.5 0.0 8.9e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EGG42763.1 - 2e-27 96.0 0.0 3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF1425 PF07233.7 EGG42765.1 - 0.042 13.4 0.2 0.059 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) HD PF01966.17 EGG42766.1 - 0.0048 16.9 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 HD domain DnaJ PF00226.26 EGG42768.1 - 3.4e-22 77.9 6.4 3.4e-22 77.9 4.4 1.9 2 0 0 2 2 2 1 DnaJ domain DPM3 PF08285.6 EGG42768.1 - 1.2 8.9 5.5 12 5.7 0.2 3.1 2 2 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF262 PF03235.9 EGG42768.1 - 2 8.3 12.4 2.7 7.8 8.6 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF262 HTH_AsnC-type PF13404.1 EGG42769.1 - 2.5e-12 46.1 1.5 3.8e-12 45.5 1.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EGG42769.1 - 2.7e-12 45.8 4.6 3e-12 45.7 2.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.16 EGG42769.1 - 1.7e-11 43.6 0.1 2.7e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 AsnC family HTH_11 PF08279.7 EGG42769.1 - 1.1e-05 24.9 0.5 1.1e-05 24.9 0.4 1.8 2 0 0 2 2 2 1 HTH domain HTH_Crp_2 PF13545.1 EGG42769.1 - 0.00096 18.9 0.1 0.0023 17.6 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.2 EGG42769.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 EGG42769.1 - 0.0023 17.5 0.1 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_10 PF04967.7 EGG42769.1 - 0.0064 16.0 0.3 0.016 14.7 0.2 1.7 1 0 0 1 1 1 1 HTH DNA binding domain DDRGK PF09756.4 EGG42769.1 - 0.0073 15.7 0.6 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 DDRGK domain NUMOD1 PF07453.8 EGG42769.1 - 0.0099 15.6 0.2 2.2 8.2 0.0 2.6 2 0 0 2 2 2 1 NUMOD1 domain TrmB PF01978.14 EGG42769.1 - 0.011 15.4 0.2 0.021 14.5 0.2 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF294_C PF10335.4 EGG42769.1 - 0.022 14.3 0.1 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain UPF0302 PF08864.5 EGG42769.1 - 0.023 14.5 0.1 0.051 13.3 0.1 1.6 1 1 0 1 1 1 0 UPF0302 domain RepL PF05732.6 EGG42769.1 - 0.037 13.2 1.3 0.046 12.9 0.2 1.6 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) GntR PF00392.16 EGG42769.1 - 0.041 13.3 0.2 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_23 PF13384.1 EGG42769.1 - 0.043 13.4 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain MarR PF01047.17 EGG42769.1 - 0.06 13.0 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.1 EGG42769.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF603 PF04645.7 EGG42769.1 - 0.2 11.5 2.6 1.8 8.4 0.0 2.6 1 1 1 3 3 3 0 Protein of unknown function, DUF603 HTH_3 PF01381.17 EGG42769.1 - 0.22 11.3 2.3 0.61 9.9 0.1 2.7 3 1 0 3 3 3 0 Helix-turn-helix HTH_19 PF12844.2 EGG42769.1 - 0.24 11.5 0.3 0.24 11.5 0.2 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain TPR_1 PF00515.23 EGG42770.1 - 2.2e-16 58.6 0.0 3.2e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG42770.1 - 1.1e-15 57.0 0.0 1.2e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EGG42770.1 - 4.6e-15 54.2 0.0 5e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42770.1 - 2.5e-11 42.4 0.0 4.4e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGG42770.1 - 3e-10 40.4 0.0 3.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG42770.1 - 3.8e-09 35.6 0.0 0.00015 21.3 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGG42770.1 - 8.2e-09 35.1 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42770.1 - 3.3e-08 33.7 0.0 3.6e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42770.1 - 4.2e-08 33.1 0.0 0.0027 18.2 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG42770.1 - 1e-07 31.7 0.0 5.1e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42770.1 - 5.4e-07 29.3 0.2 3.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGG42770.1 - 0.0011 19.0 0.1 0.0028 17.7 0.1 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 EGG42770.1 - 0.0049 15.6 0.0 0.0054 15.5 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 EGG42770.1 - 0.0097 15.8 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 EGG42770.1 - 0.021 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 EGG42770.1 - 0.023 14.7 0.1 0.85 9.6 0.0 2.0 1 1 1 2 2 2 0 Tetratrico peptide repeat Coatomer_E PF04733.9 EGG42770.1 - 0.025 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit MIT PF04212.13 EGG42770.1 - 0.039 13.8 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EGG42770.1 - 0.059 13.2 0.1 0.31 10.9 0.0 2.0 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EGG42770.1 - 0.06 13.8 0.0 1.4 9.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGG42770.1 - 0.068 12.4 0.6 13 5.1 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR PPR PF01535.15 EGG42770.1 - 0.085 12.8 0.1 2 8.5 0.0 2.2 2 0 0 2 2 2 0 PPR repeat TFIIB PF00382.14 EGG42771.1 - 4.7e-32 109.6 6.5 7.2e-18 64.1 0.3 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG42771.1 - 3.2e-10 39.1 1.1 5.6e-10 38.3 0.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EGG42771.1 - 0.00051 19.9 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain zf-ribbon_3 PF13248.1 EGG42771.1 - 0.0012 17.9 1.2 0.0024 17.0 0.8 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Cyclin_N PF00134.18 EGG42771.1 - 0.0017 17.9 0.7 0.05 13.1 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.11 EGG42771.1 - 0.005 16.1 0.0 0.39 10.0 0.0 3.4 3 1 1 4 4 4 1 Sigma-70, region 4 HTH_11 PF08279.7 EGG42771.1 - 0.0056 16.3 1.2 0.048 13.3 0.0 2.7 3 0 0 3 3 3 1 HTH domain HTH_AsnC-type PF13404.1 EGG42771.1 - 0.01 15.3 0.0 0.3 10.6 0.0 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.1 EGG42771.1 - 0.12 12.0 2.1 0.9 9.2 0.0 3.1 3 1 0 3 3 3 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EGG42771.1 - 0.16 11.4 1.5 4.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 Peptidase_M13_N PF05649.8 EGG42771.1 - 0.33 9.9 2.1 0.47 9.4 0.4 1.9 2 1 0 2 2 2 0 Peptidase family M13 zf-NADH-PPase PF09297.6 EGG42771.1 - 0.42 10.1 2.9 0.65 9.5 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 EGG42771.1 - 0.64 9.5 3.3 1.4 8.4 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Usp PF00582.21 EGG42772.1 - 2.1e-29 102.5 0.0 2.5e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family GARS_N PF02844.10 EGG42772.1 - 0.00045 20.6 0.2 0.00085 19.7 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain PTA_PTB PF01515.14 EGG42772.1 - 0.041 12.9 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase CHIPS PF11434.3 EGG42772.1 - 0.053 13.1 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Ribosomal_L21p PF00829.16 EGG42772.1 - 0.079 13.0 1.7 0.1 12.7 0.7 1.5 2 0 0 2 2 2 0 Ribosomal prokaryotic L21 protein TPR_11 PF13414.1 EGG42773.1 - 1.9e-27 94.6 6.8 7.8e-14 51.0 0.5 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGG42773.1 - 9.5e-24 81.9 9.6 5.5e-07 28.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG42773.1 - 1.8e-21 74.2 5.7 3.7e-05 23.3 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGG42773.1 - 4.1e-17 62.3 0.1 3.3e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG42773.1 - 4.5e-15 55.3 8.2 4.6e-07 29.6 0.3 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42773.1 - 3.7e-13 48.2 5.5 0.00072 19.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42773.1 - 4e-13 48.4 3.2 0.0028 17.7 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42773.1 - 1.7e-12 46.7 0.0 0.004 17.6 0.0 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42773.1 - 8.5e-10 38.8 3.5 7.8e-06 26.1 0.2 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG42773.1 - 1.5e-09 36.9 0.8 0.023 14.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EGG42773.1 - 1.5e-09 37.8 1.4 1.1e-07 31.8 0.3 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGG42773.1 - 1.1e-08 34.8 0.0 0.00055 19.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG42773.1 - 3.1e-07 30.1 1.4 0.45 10.4 0.0 4.2 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EGG42773.1 - 2.7e-06 27.4 1.2 0.16 12.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 EGG42773.1 - 4.3e-06 26.3 0.9 0.00046 19.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EGG42773.1 - 1.9e-05 24.4 4.0 0.59 10.0 0.1 4.2 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EGG42773.1 - 0.00071 19.4 0.0 2.4 7.9 0.0 3.2 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 EGG42773.1 - 0.0092 15.5 1.0 3.9 7.1 0.1 3.4 1 1 3 4 4 4 1 Protein of unknown function (DUF627) TPR_10 PF13374.1 EGG42773.1 - 0.04 13.8 0.0 4.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 EGG42773.1 - 0.053 13.5 0.4 7.9 6.7 0.1 3.0 3 0 0 3 3 2 0 PPR repeat TPR_5 PF12688.2 EGG42773.1 - 0.066 13.2 0.1 4.7 7.2 0.0 2.4 1 1 1 2 2 2 0 Tetratrico peptide repeat MerR_2 PF13591.1 EGG42773.1 - 0.069 12.7 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 MerR HTH family regulatory protein zf-C2H2_4 PF13894.1 EGG42774.1 - 0.06 13.7 0.9 0.11 12.8 0.3 1.6 1 1 1 2 2 2 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EGG42774.1 - 0.12 11.8 1.5 0.19 11.1 0.9 1.6 1 1 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 EGG42774.1 - 0.27 11.4 2.9 4.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Radical_SAM PF04055.16 EGG42775.1 - 7.2e-18 65.3 0.0 1.4e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EGG42775.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain TMEM51 PF15345.1 EGG42776.1 - 1.8e-05 24.6 0.2 1.9e-05 24.4 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 Rnf-Nqr PF02508.9 EGG42776.1 - 0.012 15.1 0.3 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein DUF4345 PF14248.1 EGG42776.1 - 0.026 13.9 0.2 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) Tetraspannin PF00335.15 EGG42776.1 - 0.05 12.8 1.2 0.065 12.4 0.9 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2964 PF11177.3 EGG42776.1 - 0.13 12.2 0.8 0.13 12.2 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) Syndecan PF01034.15 EGG42776.1 - 0.13 11.9 4.5 5.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Syndecan domain DUF2929 PF11151.3 EGG42776.1 - 0.13 12.3 2.8 3.7 7.6 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Glycophorin_A PF01102.13 EGG42776.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.0 1 1 0 2 2 2 0 Glycophorin A DUF4064 PF13273.1 EGG42776.1 - 0.21 11.6 7.9 1.4 9.0 5.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4097 PF13349.1 EGG42776.1 - 0.67 9.4 8.5 2.7 7.5 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4097) AA_permease_2 PF13520.1 EGG42776.1 - 0.87 8.0 3.3 1.1 7.7 2.3 1.0 1 0 0 1 1 1 0 Amino acid permease DUF3917 PF13055.1 EGG42776.1 - 3 8.1 6.0 0.79 10.0 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) DUF3185 PF11381.3 EGG42776.1 - 6.3 6.6 8.3 1.6 8.5 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) TrkH PF02386.11 EGG42777.1 - 8e-09 34.5 0.5 8e-09 34.5 0.4 1.0 1 0 0 1 1 1 1 Cation transport protein MoCF_biosynth PF00994.19 EGG42777.1 - 0.13 11.6 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Probable molybdopterin binding domain CBS PF00571.23 EGG42778.1 - 1.7e-22 78.9 4.3 2.2e-11 43.3 0.1 2.5 2 0 0 2 2 2 2 CBS domain TrkH PF02386.11 EGG42778.1 - 3.1e-13 49.0 32.4 2.3e-10 39.5 9.8 3.8 1 1 2 3 3 3 2 Cation transport protein zf-ribbon_3 PF13248.1 EGG42779.1 - 0.00037 19.5 0.8 0.72 9.1 0.0 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-ISL3 PF14690.1 EGG42779.1 - 0.0037 17.2 0.5 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.1 EGG42779.1 - 0.025 14.0 2.7 3.3 7.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGG42779.1 - 0.036 14.0 0.3 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 EGG42779.1 - 0.077 12.4 1.0 0.21 11.0 0.1 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_4 PF14570.1 EGG42779.1 - 0.095 12.3 9.0 0.38 10.3 6.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EGG42779.1 - 0.39 10.5 5.1 1.3 8.8 3.5 1.8 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EGG42779.1 - 1.2 8.8 3.7 2.8 7.6 2.4 1.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain C1_1 PF00130.17 EGG42779.1 - 1.5 8.5 6.9 2.7 7.7 4.8 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 EGG42780.1 - 0.017 14.2 1.0 0.03 13.5 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain HSCB_C PF07743.8 EGG42781.1 - 0.042 14.3 0.5 0.43 11.0 0.1 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain OppC_N PF12911.2 EGG42782.1 - 0.032 13.6 0.1 0.064 12.6 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2045 PF09741.4 EGG42782.1 - 0.05 12.7 0.5 0.056 12.5 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) DUF1517 PF07466.6 EGG42782.1 - 0.099 11.6 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Baculo_11_kDa PF06143.6 EGG42782.1 - 0.26 10.7 1.5 4.9 6.6 0.5 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family CagY_M PF07337.6 EGG42782.1 - 0.85 9.1 7.9 0.6 9.6 0.3 3.3 2 1 1 3 3 3 0 DC-EC Repeat DUF724 PF05266.9 EGG42783.1 - 0.0029 17.2 3.7 0.0033 17.0 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Flagellar_rod PF05149.7 EGG42783.1 - 0.0031 16.7 4.9 0.0034 16.6 3.4 1.0 1 0 0 1 1 1 1 Paraflagellar rod protein COG6 PF06419.6 EGG42783.1 - 0.0041 15.3 3.8 0.0042 15.2 2.6 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF812 PF05667.6 EGG42783.1 - 0.0049 15.4 5.6 0.0059 15.1 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Mnd1 PF03962.10 EGG42783.1 - 0.0053 16.4 5.0 0.0058 16.3 3.4 1.0 1 0 0 1 1 1 1 Mnd1 family TMF_TATA_bd PF12325.3 EGG42783.1 - 0.014 15.1 7.9 0.03 14.0 4.5 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding IL4 PF00727.13 EGG42783.1 - 0.027 14.3 0.2 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Interleukin 4 APG6 PF04111.7 EGG42783.1 - 0.034 13.2 5.9 0.037 13.0 4.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EGG42783.1 - 0.039 12.4 5.9 0.041 12.3 4.1 1.0 1 0 0 1 1 1 0 AAA domain Allexi_40kDa PF05549.6 EGG42783.1 - 0.041 13.1 3.2 0.051 12.8 2.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein GAS PF13851.1 EGG42783.1 - 0.041 13.0 7.1 0.045 12.9 4.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 EGG42783.1 - 0.041 14.0 4.5 0.077 13.1 0.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EGG42783.1 - 0.042 13.4 6.2 0.045 13.3 4.3 1.0 1 0 0 1 1 1 0 IncA protein STAT_alpha PF01017.15 EGG42783.1 - 0.042 13.5 2.9 0.1 12.3 2.0 1.6 1 1 0 1 1 1 0 STAT protein, all-alpha domain Snapin_Pallidin PF14712.1 EGG42783.1 - 0.046 14.0 4.2 2.9 8.2 0.5 2.0 1 1 1 2 2 2 0 Snapin/Pallidin ADIP PF11559.3 EGG42783.1 - 0.051 13.4 5.9 0.063 13.1 4.1 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EGG42783.1 - 0.061 13.1 3.6 0.11 12.3 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CASP_C PF08172.7 EGG42783.1 - 0.064 12.2 2.4 0.069 12.1 1.7 1.1 1 0 0 1 1 1 0 CASP C terminal ATG16 PF08614.6 EGG42783.1 - 0.074 12.8 6.8 0.081 12.7 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 EGG42783.1 - 0.079 10.8 5.2 0.087 10.6 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EGG42783.1 - 0.079 12.7 3.0 0.08 12.6 2.1 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF342 PF03961.8 EGG42783.1 - 0.094 11.1 6.2 0.1 11.0 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YkyA PF10368.4 EGG42783.1 - 0.1 11.9 5.3 0.11 11.8 3.7 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Fmp27_WPPW PF10359.4 EGG42783.1 - 0.13 10.6 5.3 0.14 10.5 3.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SlyX PF04102.7 EGG42783.1 - 0.14 12.5 3.2 0.27 11.6 0.4 1.9 1 1 0 1 1 1 0 SlyX Prefoldin PF02996.12 EGG42783.1 - 0.15 11.7 4.5 0.13 11.9 1.5 1.8 1 1 1 2 2 2 0 Prefoldin subunit Bacillus_HBL PF05791.6 EGG42783.1 - 0.15 11.3 3.0 0.16 11.2 2.0 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.10 EGG42783.1 - 0.18 11.2 7.9 0.72 9.3 0.6 2.1 1 1 1 2 2 2 0 Septum formation initiator Nup88 PF10168.4 EGG42783.1 - 0.2 9.4 6.2 0.23 9.2 4.3 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF972 PF06156.8 EGG42783.1 - 0.2 12.0 4.7 0.3 11.4 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TBPIP PF07106.8 EGG42783.1 - 0.22 11.0 6.4 0.29 10.6 4.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nsp1_C PF05064.8 EGG42783.1 - 0.22 11.1 2.3 0.31 10.6 1.6 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF3763 PF12592.3 EGG42783.1 - 0.27 10.9 2.0 9.5 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) DUF3596 PF12167.3 EGG42783.1 - 0.3 10.6 1.1 0.78 9.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3596) Prefoldin_2 PF01920.15 EGG42783.1 - 0.3 10.8 8.7 0.21 11.3 1.6 2.0 1 1 1 2 2 2 0 Prefoldin subunit Spc7 PF08317.6 EGG42783.1 - 0.31 9.6 6.3 0.35 9.4 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.8 EGG42783.1 - 0.32 10.0 3.2 0.33 9.9 2.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DASH_Dad3 PF08656.5 EGG42783.1 - 0.34 10.6 2.1 0.51 10.0 1.3 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad3 Vac_Fusion PF02346.11 EGG42783.1 - 0.34 10.3 5.1 0.69 9.3 0.2 2.3 1 1 0 2 2 2 0 Chordopoxvirus fusion protein Seryl_tRNA_N PF02403.17 EGG42783.1 - 0.36 10.8 6.6 0.43 10.6 4.6 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Nup54 PF13874.1 EGG42783.1 - 0.36 10.4 3.0 0.45 10.1 2.1 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4200 PF13863.1 EGG42783.1 - 0.39 10.6 8.7 0.48 10.3 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2951 PF11166.3 EGG42783.1 - 0.4 10.5 5.2 0.54 10.1 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) EMP24_GP25L PF01105.19 EGG42783.1 - 0.44 10.2 4.2 0.99 9.0 2.9 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CCDC-167 PF15188.1 EGG42783.1 - 0.45 10.5 7.3 0.56 10.1 5.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spore_II_R PF09551.5 EGG42783.1 - 0.48 10.4 2.0 0.56 10.2 1.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF2312 PF10073.4 EGG42783.1 - 0.48 9.8 7.6 2 7.8 1.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) XhlA PF10779.4 EGG42783.1 - 0.56 10.1 11.8 8.1 6.4 7.4 2.1 1 1 1 2 2 2 0 Haemolysin XhlA DUF3847 PF12958.2 EGG42783.1 - 0.67 9.7 9.0 3.3 7.5 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) GvpK PF05121.7 EGG42783.1 - 0.77 9.6 4.2 4.1 7.2 0.5 2.0 1 1 1 2 2 2 0 Gas vesicle protein K Atg14 PF10186.4 EGG42783.1 - 0.78 8.6 5.1 0.88 8.4 3.6 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 EGG42783.1 - 1.4 9.3 4.0 2.8 8.4 0.5 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.6 EGG42783.1 - 2 8.1 6.6 2.4 7.8 1.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 EGG42783.1 - 3.5 7.5 5.9 3.8 7.4 2.1 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) VitK2_biosynth PF02621.9 EGG42786.1 - 5.6e-65 219.0 0.0 6.2e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis YhfZ_C PF14503.1 EGG42786.1 - 0.051 12.9 0.1 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain SIS PF01380.17 EGG42788.1 - 0.00086 18.9 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 SIS domain GTP_EFTU PF00009.22 EGG42789.1 - 1.5e-56 190.8 0.5 2.3e-56 190.1 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGG42789.1 - 1.2e-27 95.8 0.0 3.9e-27 94.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EGG42789.1 - 8.5e-21 73.5 0.6 1.9e-20 72.4 0.4 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EGG42789.1 - 2.5e-20 72.1 0.0 8.3e-20 70.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGG42789.1 - 5.6e-14 52.0 0.1 2.2e-13 50.1 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Penicillinase_R PF03965.11 EGG42792.1 - 0.00089 19.3 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 Penicillinase repressor DUF4504 PF14953.1 EGG42792.1 - 0.02 14.1 0.3 2.1 7.5 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4504) Kelch_4 PF13418.1 EGG42793.1 - 0.12 12.1 0.1 0.81 9.5 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain CSTF2_hinge PF14327.1 EGG42794.1 - 0.028 14.4 0.6 0.039 14.0 0.4 1.3 1 1 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 tify PF06200.9 EGG42794.1 - 0.15 11.3 0.1 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 tify domain Zn-ribbon_8 PF09723.5 EGG42796.1 - 0.029 14.3 2.3 0.93 9.5 0.0 2.2 1 1 1 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 EGG42796.1 - 0.092 12.0 1.9 0.15 11.4 1.3 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.7 EGG42796.1 - 0.2 11.4 1.4 0.27 11.0 1.0 1.1 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Ycf66_N PF07444.6 EGG42797.1 - 3.3e-05 23.5 0.5 0.0025 17.4 0.0 2.1 1 1 1 2 2 2 1 Ycf66 protein N-terminus Cytochrom_B_N PF00033.14 EGG42797.1 - 0.013 14.8 0.2 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Oxidored_q3 PF00499.15 EGG42797.1 - 0.018 14.8 0.8 0.021 14.5 0.6 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PepSY_TM_3 PF13706.1 EGG42797.1 - 0.028 13.8 3.2 0.59 9.6 0.0 2.7 2 1 0 2 2 2 0 PepSY-associated TM helix Cytochrom_B561 PF03188.11 EGG42797.1 - 0.032 14.0 1.6 0.084 12.6 1.2 1.5 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 EmrE PF13536.1 EGG42797.1 - 0.033 14.3 1.3 0.033 14.3 0.9 1.6 1 1 1 2 2 2 0 Multidrug resistance efflux transporter PhaG_MnhG_YufB PF03334.9 EGG42797.1 - 0.076 13.0 3.4 0.26 11.3 2.1 1.8 1 1 0 1 1 1 0 Na+/H+ antiporter subunit 7kD_coat PF02495.12 EGG42797.1 - 1.8 8.0 4.2 2.4 7.6 0.1 2.4 2 1 0 2 2 2 0 7kD viral coat protein DUF1469 PF07332.6 EGG42797.1 - 3 7.5 5.1 13 5.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Mut7-C PF01927.11 EGG42800.1 - 0.0019 18.2 0.0 0.0019 18.1 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain Pox_mRNA-cap PF03341.8 EGG42800.1 - 0.096 11.7 0.2 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit WD-3 PF09765.4 EGG42801.1 - 0.037 13.3 0.7 0.037 13.3 0.5 1.0 1 0 0 1 1 1 0 WD-repeat region TrkH PF02386.11 EGG42803.1 - 1.5e-23 82.9 43.7 8.1e-21 73.9 20.8 3.6 1 1 2 3 3 3 2 Cation transport protein CBS PF00571.23 EGG42803.1 - 3.5e-20 71.5 3.2 3.3e-12 45.9 0.1 2.9 3 0 0 3 3 3 2 CBS domain DNase-RNase PF02577.9 EGG42804.1 - 1.1e-07 31.1 0.0 1.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease TDH PF03347.8 EGG42804.1 - 0.12 11.9 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF4409 PF14365.1 EGG42805.1 - 0.086 13.0 0.3 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4409) HD_4 PF13328.1 EGG42807.1 - 2.5e-22 79.2 0.1 3.1e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 HD domain DUF2387 PF09526.5 EGG42809.1 - 0.0021 17.9 0.4 0.0027 17.5 0.3 1.2 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) zf-FPG_IleRS PF06827.9 EGG42809.1 - 0.0065 16.0 1.1 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Lar_restr_allev PF14354.1 EGG42809.1 - 0.085 13.1 0.1 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.2 EGG42809.1 - 0.12 12.1 1.1 0.31 10.8 0.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon Cys_rich_KTR PF14205.1 EGG42809.1 - 0.61 9.5 4.2 1.7 8.1 2.2 2.1 1 1 1 2 2 2 0 Cysteine-rich KTR A2L_zn_ribbon PF08792.5 EGG42810.1 - 2.9 7.4 5.9 0.62 9.6 0.9 2.2 1 1 1 2 2 2 0 A2L zinc ribbon domain DUF1297 PF06973.7 EGG42811.1 - 1.1e-75 253.0 0.2 2e-75 252.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.7 EGG42811.1 - 1.1e-47 160.8 0.1 2.5e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) Flavoprotein PF02441.14 EGG42812.1 - 1.7e-30 105.3 0.7 2.3e-30 104.9 0.5 1.1 1 0 0 1 1 1 1 Flavoprotein MttA_Hcf106 PF02416.11 EGG42814.1 - 1.4e-11 43.2 1.3 1.9e-11 42.8 0.9 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family GnsAB PF08178.6 EGG42814.1 - 0.061 12.9 0.9 0.091 12.4 0.6 1.4 1 1 0 1 1 1 0 GnsA/GnsB family TatC PF00902.13 EGG42815.1 - 4.3e-57 192.9 17.6 5.2e-57 192.7 12.2 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) LEF-8 PF04941.7 EGG42818.1 - 2.4 5.7 6.0 2.6 5.6 4.2 1.0 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) zf-IS66 PF13005.2 EGG42819.1 - 0.078 12.9 1.1 0.078 12.9 0.8 2.4 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DUF2248 PF10005.4 EGG42819.1 - 0.1 11.4 2.9 0.14 11.0 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) zf-CCHC_4 PF14392.1 EGG42819.1 - 0.34 10.6 11.2 0.73 9.5 7.7 1.6 1 0 0 1 1 1 0 Zinc knuckle HlyD_3 PF13437.1 EGG42820.1 - 0.083 13.2 0.7 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 HlyD family secretion protein DUF11 PF01345.13 EGG42820.1 - 0.28 11.2 4.0 4.7 7.3 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF11 Ferritin PF00210.19 EGG42822.1 - 3e-22 78.9 0.5 3.8e-22 78.5 0.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain tRNA-synt_1d PF00750.14 EGG42823.1 - 8e-38 130.1 6.4 1.3e-27 96.6 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EGG42823.1 - 1.6e-28 99.0 0.0 1.2e-27 96.2 0.0 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1e PF01406.14 EGG42823.1 - 0.00021 20.5 0.3 0.00061 18.9 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGG42823.1 - 0.0031 16.2 0.8 0.0056 15.3 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.13 EGG42823.1 - 0.018 13.7 0.8 0.07 11.7 0.1 2.2 3 0 0 3 3 3 0 tRNA synthetases class I (K) Sarcoglycan_1 PF04790.8 EGG42823.1 - 0.028 13.6 0.1 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Amidase_6 PF12671.2 EGG42823.1 - 0.029 14.4 0.5 0.17 11.9 0.2 2.1 2 0 0 2 2 2 0 Putative amidase domain GCD14 PF08704.5 EGG42824.1 - 2.4e-35 122.2 0.1 6e-35 120.9 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EGG42824.1 - 1.6e-10 40.7 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG42824.1 - 1.4e-09 37.7 0.1 2e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EGG42824.1 - 7.7e-07 28.4 0.1 1.3e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGG42824.1 - 1.2e-06 29.0 0.0 2.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGG42824.1 - 7.3e-06 25.2 0.0 9.7e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGG42824.1 - 1.8e-05 24.7 0.0 5.4e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGG42824.1 - 2e-05 25.3 0.0 5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGG42824.1 - 5.7e-05 22.3 0.0 7.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGG42824.1 - 8e-05 23.0 0.0 0.00018 21.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG42824.1 - 0.00013 22.3 0.0 0.00042 20.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGG42824.1 - 0.00022 20.3 0.1 0.00035 19.6 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EGG42824.1 - 0.00046 19.5 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EGG42824.1 - 0.00048 19.6 0.0 0.00083 18.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Fibrillarin PF01269.12 EGG42824.1 - 0.0006 18.7 0.0 0.00094 18.1 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_25 PF13649.1 EGG42824.1 - 0.0084 16.4 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGG42824.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EGG42824.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGG42824.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EGG42824.1 - 0.04 13.6 0.0 0.068 12.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EGG42824.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Carb_kinase PF01256.12 EGG42825.1 - 1.8e-47 161.7 0.7 2e-47 161.4 0.5 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EGG42825.1 - 6e-10 38.7 0.2 1.1e-09 37.8 0.1 1.4 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EGG42825.1 - 2.1e-06 27.1 0.1 3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_M20 PF01546.23 EGG42826.1 - 2.5e-29 102.1 0.0 3.6e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGG42826.1 - 1.6e-12 47.1 0.0 2.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DoxX PF07681.7 EGG42827.1 - 2.5e-14 53.4 5.6 2.5e-14 53.4 3.9 1.7 1 1 0 1 1 1 1 DoxX DoxX_2 PF13564.1 EGG42827.1 - 8.9e-07 28.8 7.8 1.6e-06 28.0 5.4 1.4 1 1 0 1 1 1 1 DoxX-like family DoxD PF04173.8 EGG42827.1 - 6.7e-06 25.8 6.1 1.5e-05 24.7 4.1 1.5 1 1 1 2 2 2 1 TQO small subunit DoxD DUF4225 PF13988.1 EGG42827.1 - 0.59 9.5 11.7 0.33 10.3 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4225) SURF4 PF02077.10 EGG42827.1 - 1.3 8.3 5.0 7.3 5.8 3.5 2.0 1 1 0 1 1 1 0 SURF4 family Proteasome PF00227.21 EGG42828.1 - 6.2e-46 156.0 0.0 7.6e-46 155.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PUA PF01472.15 EGG42829.1 - 8.1e-17 60.7 0.6 1.1e-16 60.3 0.4 1.2 1 0 0 1 1 1 1 PUA domain DUF4362 PF14275.1 EGG42829.1 - 0.098 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) Homoserine_dh PF00742.14 EGG42830.1 - 1.6e-54 184.2 0.2 2.8e-54 183.4 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EGG42830.1 - 1.2e-06 28.8 0.0 3.1e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGG42830.1 - 3.4e-06 26.8 0.3 8.5e-06 25.5 0.2 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SelR PF01641.13 EGG42831.1 - 1.6e-51 173.1 0.2 1.9e-51 172.9 0.2 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 EGG42831.1 - 0.0027 17.7 0.5 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EGG42831.1 - 0.0095 15.7 1.9 1.6 8.5 0.3 2.3 2 0 0 2 2 2 2 Double zinc ribbon DUF678 PF05077.7 EGG42831.1 - 0.057 13.4 0.2 7.2 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) RIG-I_C-RD PF11648.3 EGG42831.1 - 0.084 12.7 1.5 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of RIG-I HECT_2 PF09814.4 EGG42831.1 - 0.19 10.3 1.1 0.78 8.3 0.8 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-ribbon_3 PF13248.1 EGG42831.1 - 0.22 10.7 4.7 2.6 7.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGG42831.1 - 0.28 10.5 6.4 1.3 8.4 0.6 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Lar_restr_allev PF14354.1 EGG42831.1 - 0.49 10.7 4.7 2.2 8.6 2.4 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EGG42831.1 - 0.82 9.5 5.2 5.3 6.9 1.4 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF983 PF06170.7 EGG42831.1 - 0.91 9.6 2.8 3.7 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Prok-RING_1 PF14446.1 EGG42831.1 - 1.2 8.8 5.8 7 6.4 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Thy1 PF02511.10 EGG42832.1 - 7.3e-29 100.4 2.4 5e-15 55.3 2.8 2.7 2 2 0 2 2 2 2 Thymidylate synthase complementing protein DUF722 PF05263.6 EGG42832.1 - 0.024 14.7 1.7 0.26 11.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF722) NOSIC PF08060.8 EGG42832.1 - 0.037 13.8 0.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 NOSIC (NUC001) domain TerC PF03741.11 EGG42834.1 - 5.7e-51 172.5 13.1 5.7e-51 172.5 9.1 1.7 2 0 0 2 2 2 1 Integral membrane protein TerC family Phage_holin_5 PF06946.6 EGG42835.1 - 0.41 10.8 5.5 0.17 12.0 1.5 1.9 2 0 0 2 2 2 0 Phage holin HCV_NS4b PF01001.14 EGG42835.1 - 1.3 8.3 9.3 0.37 10.1 2.5 2.2 2 1 1 3 3 3 0 Hepatitis C virus non-structural protein NS4b YvbH_ext PF11724.3 EGG42836.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region DUF3834 PF12916.2 EGG42836.1 - 0.11 11.4 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Ribosomal_L29 PF00831.18 EGG42837.1 - 0.049 13.3 2.1 2.1 8.0 0.3 2.9 2 1 1 3 3 3 0 Ribosomal L29 protein CBFD_NFYB_HMF PF00808.18 EGG42837.1 - 0.06 13.4 0.2 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Baculo_PEP_C PF04513.7 EGG42837.1 - 0.06 13.1 0.7 0.13 12.0 0.5 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2458 PF10454.4 EGG42837.1 - 0.085 12.7 6.8 0.14 12.0 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF4446 PF14584.1 EGG42837.1 - 1.1 9.0 5.5 1.8 8.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4164 PF13747.1 EGG42837.1 - 1.7 8.8 9.7 2.3 8.4 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TMPIT PF07851.8 EGG42837.1 - 6 5.8 8.7 18 4.3 5.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein AMP-binding PF00501.23 EGG42838.1 - 2.9e-94 315.8 0.0 3.7e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG42838.1 - 1.6e-19 70.6 0.2 3.9e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PAS_9 PF13426.1 EGG42839.1 - 1.2e-11 44.8 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGG42839.1 - 5.3e-09 35.8 0.0 6.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EGG42839.1 - 0.0005 20.0 0.0 0.00062 19.7 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EGG42839.1 - 0.0015 18.6 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold LXG PF04740.7 EGG42839.1 - 0.0036 17.1 3.8 0.0049 16.6 2.6 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily FlxA PF14282.1 EGG42839.1 - 0.081 12.8 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 FlxA-like protein PAS_8 PF13188.1 EGG42839.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 PAS domain DUF285 PF03382.9 EGG42839.1 - 0.14 11.7 3.1 0.56 9.7 2.1 1.9 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 HTH_20 PF12840.2 EGG42840.1 - 4.2e-08 32.8 0.0 1.8e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 EGG42840.1 - 3.9e-06 26.4 0.1 0.00091 18.8 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 EGG42840.1 - 6.8e-05 22.1 0.4 0.0008 18.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF4423 PF14394.1 EGG42840.1 - 0.00065 19.2 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR PF01047.17 EGG42840.1 - 0.001 18.7 0.4 1.6 8.5 0.0 3.1 3 0 0 3 3 3 2 MarR family DUF2250 PF10007.4 EGG42840.1 - 0.002 17.9 1.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_45 PF14947.1 EGG42840.1 - 0.0034 17.1 1.1 0.055 13.2 0.0 2.6 3 0 0 3 3 3 1 Winged helix-turn-helix HTH_27 PF13463.1 EGG42840.1 - 0.0059 16.9 0.1 0.63 10.3 0.0 2.4 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_5 PF01022.15 EGG42840.1 - 0.0072 15.9 0.1 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family B-block_TFIIIC PF04182.7 EGG42840.1 - 0.016 15.0 0.3 17 5.3 0.0 3.3 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC TrmB PF01978.14 EGG42840.1 - 0.024 14.3 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF3449 PF11931.3 EGG42840.1 - 0.031 13.7 1.1 0.049 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Mrr_N PF14338.1 EGG42840.1 - 0.098 12.7 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Mrr N-terminal domain DZR PF12773.2 EGG42841.1 - 0.029 14.1 9.7 0.042 13.6 6.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon XkdN PF08890.6 EGG42841.1 - 0.18 11.5 0.4 0.2 11.3 0.3 1.0 1 0 0 1 1 1 0 Phage XkdN-like protein GF_recep_IV PF14843.1 EGG42841.1 - 0.19 11.3 7.8 0.2 11.2 5.4 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV zf-met PF12874.2 EGG42841.1 - 0.33 11.2 4.4 4.1 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PolC_DP2 PF03833.8 EGG42841.1 - 0.38 8.3 6.2 0.39 8.3 4.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.1 EGG42841.1 - 0.7 9.1 7.0 0.13 11.5 1.4 2.0 1 1 1 2 2 2 0 zinc-ribbon domain C1_2 PF03107.11 EGG42841.1 - 1 9.5 10.9 6 7.0 1.4 3.7 3 1 0 3 3 3 0 C1 domain zf-dskA_traR PF01258.12 EGG42841.1 - 1.5 8.5 7.8 1.3 8.7 1.5 2.4 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C2H2_jaz PF12171.3 EGG42841.1 - 1.7 8.9 6.4 2.2 8.5 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 EGG42841.1 - 2.5 7.8 10.3 6.2 6.5 0.2 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zf-B_box PF00643.19 EGG42841.1 - 3 7.7 12.2 9.4 6.2 7.6 2.1 1 1 0 1 1 1 0 B-box zinc finger Zn_Tnp_IS1595 PF12760.2 EGG42841.1 - 3.3 7.5 7.7 5.4 6.9 5.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EGG42841.1 - 3.8 7.1 7.5 13 5.4 5.2 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger DUF1272 PF06906.6 EGG42841.1 - 6.2 6.7 10.6 19 5.2 7.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MYND PF01753.13 EGG42841.1 - 7.3 6.5 11.1 47 3.9 7.7 2.1 1 1 0 1 1 1 0 MYND finger GBP PF02263.14 EGG42842.1 - 0.023 13.7 0.1 0.025 13.6 0.1 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain TauE PF01925.14 EGG42843.1 - 0.013 14.9 0.0 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DZR PF12773.2 EGG42843.1 - 0.094 12.5 3.5 0.13 12.0 2.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon SdpI PF13630.1 EGG42843.1 - 0.2 11.3 2.7 0.28 10.9 1.9 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family zf-ribbon_3 PF13248.1 EGG42843.1 - 1.6 8.0 5.6 2.6 7.3 3.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain XPG_I PF00867.13 EGG42844.1 - 4e-24 84.4 0.0 8.3e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGG42844.1 - 1e-21 77.0 0.1 6.9e-21 74.4 0.0 2.3 3 0 0 3 3 3 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EGG42844.1 - 0.00067 19.8 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF998 PF06197.8 EGG42845.1 - 0.0039 16.5 0.3 0.0044 16.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF998) EmrE PF13536.1 EGG42845.1 - 0.011 15.8 1.0 0.015 15.5 0.7 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter DUF2339 PF10101.4 EGG42845.1 - 0.012 13.9 0.5 0.013 13.8 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF2910 PF11139.3 EGG42845.1 - 0.019 14.0 0.1 0.022 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) PTPS_related PF10131.4 EGG42845.1 - 0.074 11.1 0.1 0.077 11.1 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF2162 PF09930.4 EGG42845.1 - 0.088 11.9 0.2 0.089 11.9 0.1 1.0 1 0 0 1 1 1 0 Predicted transporter (DUF2162) VIT1 PF01988.14 EGG42845.1 - 0.1 12.1 1.6 0.12 11.8 1.1 1.0 1 0 0 1 1 1 0 VIT family PrgI PF12666.2 EGG42845.1 - 0.12 12.5 0.4 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 PrgI family protein DUF1056 PF06341.6 EGG42845.1 - 0.61 10.1 4.5 0.28 11.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) DUF4064 PF13273.1 EGG42845.1 - 0.89 9.6 6.1 0.72 9.9 0.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF308 PF03729.8 EGG42845.1 - 1.5 8.8 9.5 6.8 6.7 6.6 1.8 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) SdpI PF13630.1 EGG42845.1 - 4.4 7.0 9.8 25 4.6 6.9 1.9 1 1 0 1 1 1 0 SdpI/YhfL protein family YodL PF14191.1 EGG42846.1 - 0.024 15.1 0.4 0.03 14.7 0.3 1.1 1 0 0 1 1 1 0 YodL-like SAC3 PF12209.3 EGG42846.1 - 0.041 14.0 0.0 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain HTH_45 PF14947.1 EGG42848.1 - 1e-07 31.6 0.2 1.1e-07 31.6 0.1 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.1 EGG42848.1 - 0.0031 17.1 0.0 0.0034 17.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_34 PF13601.1 EGG42848.1 - 0.0051 16.8 0.1 0.0061 16.5 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.15 EGG42848.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Avidin PF01382.12 EGG42850.1 - 0.12 12.6 1.5 0.14 12.4 1.0 1.1 1 0 0 1 1 1 0 Avidin family Hormone_2 PF00123.15 EGG42850.1 - 5.6 6.8 6.1 23 4.9 0.1 3.2 3 0 0 3 3 3 0 Peptide hormone Guanylate_cyc PF00211.15 EGG42852.1 - 2e-17 63.1 0.0 2.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AHSA1 PF08327.6 EGG42854.1 - 3.7e-21 75.5 0.3 4.2e-21 75.3 0.2 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EGG42854.1 - 0.0094 16.1 0.0 0.011 15.9 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport S_locus_glycop PF00954.15 EGG42854.1 - 0.015 15.5 0.3 0.025 14.8 0.2 1.3 1 0 0 1 1 1 0 S-locus glycoprotein family Asp PF00026.18 EGG42854.1 - 0.027 13.7 0.2 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease COXG PF06240.8 EGG42854.1 - 0.045 13.4 0.0 0.089 12.4 0.0 1.5 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) DUF212 PF02681.9 EGG42855.1 - 0.4 10.4 1.9 3 7.5 0.0 2.0 2 0 0 2 2 2 0 Divergent PAP2 family DUF1410 PF07198.6 EGG42857.1 - 0.79 10.0 3.0 5.1 7.4 2.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) TGS PF02824.16 EGG42859.1 - 8.9e-21 73.4 0.1 2.5e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EGG42859.1 - 1.5e-20 73.2 0.1 4.9e-20 71.6 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG42859.1 - 2.2e-15 56.2 1.0 6.1e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EGG42859.1 - 6.3e-05 22.8 0.1 0.48 10.2 0.1 2.9 2 0 0 2 2 2 2 Dynamin family cobW PF02492.14 EGG42859.1 - 0.00083 18.8 0.7 0.18 11.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 EGG42859.1 - 0.001 18.2 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Arf PF00025.16 EGG42859.1 - 0.0027 16.9 1.7 0.031 13.5 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 EGG42859.1 - 0.0033 16.6 0.2 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EGG42859.1 - 0.0056 15.9 1.3 0.0066 15.6 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EGG42859.1 - 0.01 14.6 0.1 0.053 12.2 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 EGG42859.1 - 0.011 16.2 0.0 0.035 14.5 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 EGG42859.1 - 0.018 15.0 0.1 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG42859.1 - 0.023 14.8 0.1 0.28 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EGG42859.1 - 0.023 14.4 0.8 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGG42859.1 - 0.029 14.3 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 EGG42859.1 - 0.058 12.7 1.2 4 6.7 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_33 PF13671.1 EGG42859.1 - 0.073 12.9 0.1 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGG42859.1 - 0.087 13.6 0.5 0.36 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Baculo_FP PF03258.9 EGG42859.1 - 0.13 11.3 7.4 0.66 9.0 0.0 2.8 3 0 0 3 3 3 0 Baculovirus FP protein DUF904 PF06005.7 EGG42859.1 - 1.1 9.5 5.4 0.28 11.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF504 PF04457.7 EGG42860.1 - 0.0041 17.2 0.1 0.0068 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF504) DUF2185 PF09951.4 EGG42860.1 - 0.031 14.0 0.1 0.05 13.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2185) DUF4296 PF14129.1 EGG42862.1 - 0.066 13.3 4.4 0.32 11.1 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) Homeobox PF00046.24 EGG42862.1 - 0.071 12.7 1.2 0.11 12.1 0.8 1.3 1 0 0 1 1 1 0 Homeobox domain FB_lectin PF07367.6 EGG42862.1 - 0.11 12.1 0.5 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 Fungal fruit body lectin 7TM_GPCR_Srw PF10324.4 EGG42862.1 - 0.12 11.4 0.8 0.14 11.2 0.5 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw TDH PF03347.8 EGG42862.1 - 0.13 11.8 0.9 2 7.9 0.1 2.0 1 1 1 2 2 2 0 Vibrio thermostable direct hemolysin Mst1_SARAH PF11629.3 EGG42862.1 - 0.46 10.3 3.7 0.25 11.2 0.5 2.0 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 Band_7 PF01145.20 EGG42863.1 - 4.5e-25 88.5 6.2 6.9e-25 87.9 4.2 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S8 PF00082.17 EGG42864.1 - 4.9e-26 91.5 7.6 3.7e-18 65.6 0.4 2.3 2 0 0 2 2 2 2 Subtilase family TGFb_propeptide PF00688.13 EGG42865.1 - 0.013 14.7 0.1 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 TGF-beta propeptide DZR PF12773.2 EGG42866.1 - 0.012 15.3 0.9 0.016 15.0 0.6 1.1 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EGG42866.1 - 0.024 14.3 0.9 0.03 13.9 0.6 1.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EGG42866.1 - 0.043 13.6 1.3 0.059 13.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 EGG42866.1 - 0.067 12.4 3.5 0.93 8.7 0.4 2.2 1 1 1 2 2 2 0 zinc-ribbon domain PolC_DP2 PF03833.8 EGG42866.1 - 0.067 10.8 0.0 0.067 10.8 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_4 PF14570.1 EGG42866.1 - 0.078 12.5 0.9 0.11 12.1 0.6 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_2 PF13240.1 EGG42866.1 - 0.11 11.9 3.3 5.5 6.6 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2321 PF10083.4 EGG42866.1 - 0.12 11.8 0.2 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DNA_ligase_ZBD PF03119.11 EGG42866.1 - 0.2 11.3 2.8 2.4 7.9 0.5 2.2 1 1 1 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain ASFV_L11L PF05293.6 EGG42866.1 - 0.23 11.6 1.1 0.29 11.2 0.8 1.2 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein TF_Zn_Ribbon PF08271.7 EGG42866.1 - 0.5 9.7 7.3 3.5 7.0 0.4 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding A2M_N PF01835.14 EGG42867.1 - 1.9e-32 111.4 6.0 2.8e-05 24.2 0.0 9.4 7 3 0 7 7 7 5 MG2 domain LTD PF00932.14 EGG42867.1 - 4.6e-11 42.8 5.5 1e-10 41.7 0.8 3.5 3 0 0 3 3 3 1 Lamin Tail Domain A2M_N_2 PF07703.9 EGG42867.1 - 5.3e-05 23.0 1.6 0.072 12.8 0.0 4.8 5 0 0 5 5 5 1 Alpha-2-macroglobulin family N-terminal region FlgD_ig PF13860.1 EGG42867.1 - 5.1 6.9 11.1 2.5 7.9 0.0 5.2 8 0 0 8 8 8 0 FlgD Ig-like domain DUF367 PF04034.8 EGG42868.1 - 2.7e-36 123.9 0.0 3.7e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EGG42868.1 - 6.6e-07 28.8 0.1 1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SBP_bac_5 PF00496.17 EGG42869.1 - 2.5e-30 105.5 8.5 5e-24 84.8 0.0 3.5 3 1 0 3 3 3 3 Bacterial extracellular solute-binding proteins, family 5 Middle Mrr_cat PF04471.7 EGG42871.1 - 0.00047 19.9 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease NERD PF08378.6 EGG42871.1 - 0.028 14.6 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Nuclease-related domain Rhodanese PF00581.15 EGG42871.1 - 0.13 12.6 0.0 5.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain DUF2070 PF09843.4 EGG42872.1 - 2.2e-44 151.0 0.0 3.9e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Sec61_beta PF03911.11 EGG42873.1 - 2.4e-14 52.8 0.4 2.8e-14 52.6 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family Auto_anti-p27 PF06677.7 EGG42874.1 - 8e-08 31.9 1.9 1.2e-07 31.3 1.3 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1178 PF06676.6 EGG42874.1 - 0.018 15.2 0.5 0.021 15.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Abi_C PF14355.1 EGG42874.1 - 0.044 13.7 0.6 0.079 12.9 0.4 1.4 1 0 0 1 1 1 0 Abortive infection C-terminus TIP120 PF08623.5 EGG42874.1 - 0.07 12.7 4.4 0.081 12.4 3.1 1.1 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) zf-C4pol PF14260.1 EGG42874.1 - 0.76 9.8 3.6 4.3 7.4 2.5 2.2 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta SUI1 PF01253.17 EGG42875.1 - 2.9e-21 75.0 0.1 3.5e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Abi PF02517.11 EGG42876.1 - 2.2e-12 46.9 14.2 1.2e-11 44.5 9.9 2.2 1 1 0 1 1 1 1 CAAX protease self-immunity CofC PF01983.11 EGG42877.1 - 2.3e-13 49.6 3.1 2.6e-13 49.4 2.1 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.2 EGG42877.1 - 3.5e-06 27.1 0.0 4.1e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4504 PF14953.1 EGG42877.1 - 0.015 14.5 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) CTP_transf_3 PF02348.14 EGG42877.1 - 0.08 12.5 0.4 0.13 11.8 0.2 1.3 1 1 0 1 1 1 0 Cytidylyltransferase UPF0052 PF01933.13 EGG42878.1 - 3.5e-48 164.4 0.0 4.4e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF2479 PF10651.4 EGG42879.1 - 0.017 14.6 0.3 0.034 13.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2479) Methyltransf_23 PF13489.1 EGG42881.1 - 4.7e-20 71.9 0.0 5.8e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG42881.1 - 1.4e-19 70.3 0.0 4.2e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG42881.1 - 3.7e-18 65.5 0.4 5.3e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG42881.1 - 1.4e-15 57.5 0.0 2.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG42881.1 - 3.8e-12 46.7 0.0 6.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGG42881.1 - 1.2e-10 41.1 0.0 1.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 EGG42881.1 - 1.6e-10 41.2 0.0 3.7e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGG42881.1 - 1.2e-09 37.3 0.1 2.9e-09 36.0 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EGG42881.1 - 5.2e-09 35.4 0.6 1.5e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Ubie_methyltran PF01209.13 EGG42881.1 - 1.7e-08 33.8 0.6 2.4e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EGG42881.1 - 1.2e-07 31.2 0.1 1.2e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DOT1 PF08123.8 EGG42881.1 - 2.3e-05 23.7 0.1 0.00025 20.3 0.0 2.1 1 1 1 2 2 2 1 Histone methylation protein DOT1 AdoMet_MTase PF07757.8 EGG42881.1 - 9.4e-05 22.4 0.9 0.00019 21.5 0.0 1.9 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.15 EGG42881.1 - 0.00012 21.2 0.6 0.00015 20.9 0.4 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GidB PF02527.10 EGG42881.1 - 0.00031 19.9 0.5 0.0039 16.3 0.0 2.1 1 1 0 2 2 2 1 rRNA small subunit methyltransferase G MTS PF05175.9 EGG42881.1 - 0.00059 19.2 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EGG42881.1 - 0.00091 18.4 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EGG42881.1 - 0.0023 17.6 0.1 0.0063 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 EGG42881.1 - 0.0026 16.6 0.1 0.0036 16.2 0.1 1.3 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_26 PF13659.1 EGG42881.1 - 0.0042 17.1 0.0 0.0087 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG42881.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1251 PF06856.6 EGG42881.1 - 0.044 13.2 0.2 0.078 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) Methyltransf_2 PF00891.13 EGG42881.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase DUF4363 PF14276.1 EGG42882.1 - 9e-06 25.3 2.8 0.0031 17.2 0.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4363) Glyco_hyd_65N_2 PF14498.1 EGG42882.1 - 0.012 15.3 0.1 0.048 13.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain HTH_Tnp_1 PF01527.15 EGG42882.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Transposase FAD_oxidored PF12831.2 EGG42883.1 - 7.9e-16 58.1 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGG42883.1 - 3.2e-14 52.7 0.0 1.1e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGG42883.1 - 5.8e-14 51.7 0.9 2.4e-08 33.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGG42883.1 - 8.6e-12 44.4 0.2 1.3e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EGG42883.1 - 1.7e-11 43.6 0.4 4.5e-07 29.0 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EGG42883.1 - 3.4e-09 36.1 0.0 5.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGG42883.1 - 2.4e-08 34.1 2.1 5.2e-08 32.9 1.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG42883.1 - 3.3e-08 32.4 0.4 2.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGG42883.1 - 7.7e-07 28.4 1.8 9.4e-06 24.8 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EGG42883.1 - 9.3e-07 29.1 0.1 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG42883.1 - 2.9e-06 27.1 0.1 7.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGG42883.1 - 3e-06 26.3 0.8 8.4e-06 24.8 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EGG42883.1 - 2.4e-05 24.6 1.2 0.015 15.7 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGG42883.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 EGG42883.1 - 0.075 12.1 0.3 0.61 9.1 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase GDI PF00996.13 EGG42883.1 - 0.079 11.2 0.2 1.7 6.9 0.1 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor TrkA_N PF02254.13 EGG42883.1 - 0.11 12.4 0.1 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF3797 PF12677.2 EGG42884.1 - 0.033 13.8 0.4 0.051 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-Mss51 PF13824.1 EGG42884.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Adeno_100 PF02438.11 EGG42884.1 - 0.13 10.4 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Late 100kD protein zf-ribbon_3 PF13248.1 EGG42884.1 - 0.2 10.9 1.4 0.43 9.8 1.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-ISL3 PF14690.1 EGG42884.1 - 0.28 11.2 1.2 0.86 9.6 0.8 2.0 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2 PF00096.21 EGG42884.1 - 0.4 11.1 0.3 0.4 11.1 0.2 1.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 EGG42884.1 - 0.61 10.2 2.2 0.85 9.7 0.3 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF99 PF01949.11 EGG42885.1 - 8.8e-57 191.2 0.0 9.8e-57 191.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 DUF2608 PF11019.3 EGG42885.1 - 0.076 11.9 0.5 0.16 10.8 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) adh_short_C2 PF13561.1 EGG42886.1 - 7.8e-39 133.8 0.3 9.5e-39 133.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG42886.1 - 3.1e-32 111.8 0.0 3.8e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG42886.1 - 8.6e-09 35.3 0.1 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGG42886.1 - 1.2e-06 28.6 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGG42886.1 - 4.4e-05 23.0 2.4 4.5e-05 22.9 0.5 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EGG42886.1 - 0.00017 21.9 0.9 0.00034 20.9 0.3 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EGG42886.1 - 0.00098 18.8 0.2 0.0015 18.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EGG42886.1 - 0.0049 15.7 2.4 0.0066 15.3 1.6 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.10 EGG42886.1 - 0.013 15.1 0.2 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.5 EGG42886.1 - 0.093 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_11 PF14833.1 EGG42887.1 - 1.5e-10 41.1 0.0 1.7e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EGG42888.1 - 3.4e-39 134.3 0.4 4.5e-39 133.9 0.3 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGG42888.1 - 2.2e-09 37.6 0.5 1.1e-08 35.4 0.3 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGG42888.1 - 4.6e-07 30.0 0.3 7.3e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGG42888.1 - 7.3e-07 28.7 1.2 0.00016 21.1 0.1 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EGG42888.1 - 5.8e-06 25.5 0.1 9.5e-06 24.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EGG42888.1 - 2.8e-05 23.6 0.1 4.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EGG42888.1 - 6.3e-05 22.3 0.2 0.00012 21.4 0.1 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EGG42888.1 - 0.00014 21.5 0.2 0.0024 17.5 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGG42888.1 - 0.00034 20.3 0.1 0.0016 18.1 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.4 EGG42888.1 - 0.00035 20.2 0.0 0.086 12.5 0.0 2.2 1 1 1 2 2 2 2 Rossmann-like domain NAD_binding_11 PF14833.1 EGG42888.1 - 0.00059 19.8 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NmrA PF05368.8 EGG42888.1 - 0.03 13.5 0.2 0.056 12.6 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 EGG42888.1 - 0.041 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding zf-H2C2_5 PF13909.1 EGG42890.1 - 0.00058 19.9 1.6 0.00096 19.2 1.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EGG42890.1 - 0.00094 19.3 1.2 0.0016 18.6 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG42890.1 - 0.0013 18.9 0.8 0.0021 18.2 0.5 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger RRN7 PF11781.3 EGG42890.1 - 0.07 12.6 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF3505 PF12013.3 EGG42890.1 - 0.081 13.1 0.0 0.094 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) DUF1270 PF06900.6 EGG42891.1 - 7.9 6.7 7.1 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) Peripla_BP_2 PF01497.13 EGG42892.1 - 1.6e-45 155.0 0.0 1.9e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Ribosomal_L17 PF01196.14 EGG42892.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L17 DUF650 PF04894.7 EGG42893.1 - 8.7e-73 245.1 0.0 1.1e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF650) DUF651 PF04895.7 EGG42893.1 - 4.6e-35 119.5 0.0 7.2e-35 118.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF651) Exosortase_EpsH PF09721.5 EGG42894.1 - 6.4e-05 22.2 26.5 0.00019 20.7 18.3 1.6 1 1 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF4231 PF14015.1 EGG42894.1 - 3.8 7.5 7.9 0.41 10.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF998 PF06197.8 EGG42894.1 - 9 5.5 22.3 0.51 9.6 8.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF998) IMS PF00817.15 EGG42895.1 - 1.9e-40 138.0 0.2 2.8e-39 134.3 0.1 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EGG42895.1 - 1.4e-17 63.8 1.2 4.2e-17 62.2 0.3 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGG42895.1 - 7.1e-08 32.0 0.0 1.9e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.3 EGG42895.1 - 0.0045 16.8 0.2 0.074 12.9 0.0 2.7 2 2 0 2 2 2 1 Pathogenicity locus DNA_pol_lambd_f PF10391.4 EGG42895.1 - 0.027 14.0 0.1 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda DUF4055 PF13264.1 EGG42895.1 - 0.093 12.8 0.3 5.7 7.0 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) DUF2524 PF10732.4 EGG42895.1 - 0.16 12.1 2.3 0.7 10.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) NPV_P10 PF05531.7 EGG42895.1 - 0.75 10.0 5.7 5.7 7.2 1.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EGG42895.1 - 1.7 8.7 8.3 1.6 8.8 4.4 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Alba PF01918.16 EGG42897.1 - 5.9e-11 41.7 1.2 8.1e-11 41.3 0.8 1.2 1 0 0 1 1 1 1 Alba DUF605 PF04652.11 EGG42897.1 - 2.9 7.1 11.8 3 7.1 8.2 1.1 1 0 0 1 1 1 0 Vta1 like LysE PF01810.13 EGG42899.1 - 4.5e-27 94.5 15.7 5.7e-27 94.2 10.9 1.0 1 0 0 1 1 1 1 LysE type translocator CRPA PF05745.6 EGG42899.1 - 0.042 13.6 1.3 0.067 12.9 0.1 1.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) PAC2 PF09754.4 EGG42900.1 - 5.1e-17 62.4 0.0 6e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DS PF01916.12 EGG42901.1 - 2.3e-72 243.6 0.3 2.7e-72 243.4 0.2 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase NAD_binding_5 PF07994.7 EGG42902.1 - 4.8e-43 147.7 0.0 3.3e-42 144.9 0.0 1.9 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGG42902.1 - 9.7e-31 105.9 0.4 1.3e-29 102.3 0.0 2.2 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase UPF0081 PF03652.10 EGG42902.1 - 0.011 15.8 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0081) MS_channel PF00924.13 EGG42902.1 - 0.039 13.2 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel DUF257 PF03192.8 EGG42902.1 - 0.051 12.8 0.5 0.27 10.5 0.1 2.0 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 CobU PF02283.11 EGG42902.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SMC_N PF02463.14 EGG42903.1 - 2.9e-48 164.0 34.5 2.9e-26 92.0 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGG42903.1 - 5.9e-18 64.9 0.0 2.6e-17 62.8 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EGG42903.1 - 2.2e-16 60.8 3.8 2.2e-16 60.8 2.7 7.3 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EGG42903.1 - 1.5e-08 35.0 21.2 1.5e-06 28.3 3.8 5.0 2 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EGG42903.1 - 5.7e-05 22.5 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tubulin_3 PF14881.1 EGG42903.1 - 0.00096 18.6 0.1 0.0058 16.1 0.1 2.4 1 0 0 1 1 1 1 Tubulin domain SbcCD_C PF13558.1 EGG42903.1 - 0.017 15.0 0.0 0.08 12.8 0.0 2.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EGG42903.1 - 0.08 12.3 0.0 0.59 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGG42903.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain APG6 PF04111.7 EGG42903.1 - 3 6.8 105.9 0.01 14.8 8.8 7.5 3 2 5 8 8 8 0 Autophagy protein Apg6 ABC_tran PF00005.22 EGG42904.1 - 7.1e-34 117.0 0.1 1e-33 116.5 0.1 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.7 EGG42904.1 - 6.2e-18 64.9 0.2 1.3e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.1 EGG42904.1 - 4.4e-06 26.8 3.0 0.0042 17.0 0.3 2.3 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EGG42904.1 - 2.1e-05 23.8 0.4 3.6e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGG42904.1 - 0.00013 21.9 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EGG42904.1 - 0.00015 20.9 6.7 0.078 12.0 2.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGG42904.1 - 0.00016 20.9 0.2 0.00037 19.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGG42904.1 - 0.00017 21.8 0.4 0.00033 20.9 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG42904.1 - 0.00031 20.8 0.9 0.0044 17.1 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGG42904.1 - 0.00033 20.1 0.0 0.0011 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EGG42904.1 - 0.00042 19.3 0.3 0.00075 18.4 0.1 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EGG42904.1 - 0.00048 19.6 0.1 0.001 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGG42904.1 - 0.00056 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 EGG42904.1 - 0.0013 18.8 0.6 0.021 15.0 0.4 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGG42904.1 - 0.003 18.3 0.1 0.0075 17.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EGG42904.1 - 0.004 16.7 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EGG42904.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGG42904.1 - 0.008 16.5 0.1 0.008 16.5 0.1 1.9 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGG42904.1 - 0.0081 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_13 PF13166.1 EGG42904.1 - 0.014 13.8 0.0 2.7 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGG42904.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EGG42904.1 - 0.022 14.2 0.2 0.069 12.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EGG42904.1 - 0.024 14.3 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 EGG42904.1 - 0.026 14.2 0.0 0.081 12.6 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain KaiC PF06745.8 EGG42904.1 - 0.032 13.3 0.2 0.25 10.4 0.1 2.1 2 0 0 2 2 2 0 KaiC DUF87 PF01935.12 EGG42904.1 - 0.034 13.9 1.7 0.046 13.5 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EGG42904.1 - 0.045 13.2 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EGG42904.1 - 0.047 12.5 0.1 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.18 EGG42904.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EGG42904.1 - 0.057 13.1 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGG42904.1 - 0.065 13.1 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain PRK PF00485.13 EGG42904.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 EGG42904.1 - 0.073 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.1 EGG42904.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EGG42904.1 - 0.12 12.2 0.1 0.6 9.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Methyltransf_33 PF10017.4 EGG42905.1 - 2.6e-44 150.1 1.3 4.1e-44 149.5 0.9 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_23 PF13489.1 EGG42905.1 - 0.00037 20.2 0.0 0.0053 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGG42905.1 - 0.036 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FGE-sulfatase PF03781.11 EGG42906.1 - 1.5e-48 165.4 2.7 2.8e-48 164.5 1.9 1.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGG42906.1 - 1e-11 45.2 0.1 3.9e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 DinB superfamily E3_UbLigase_R4 PF13764.1 EGG42906.1 - 0.19 9.5 1.3 0.35 8.7 0.9 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 ProRS-C_1 PF09180.6 EGG42907.1 - 7e-20 70.7 3.2 1.1e-19 70.1 1.1 2.2 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EGG42907.1 - 9.3e-18 63.9 0.2 2.4e-17 62.6 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EGG42907.1 - 1.7e-16 60.2 0.1 3.1e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Hydrolase PF00702.21 EGG42910.1 - 2.8e-08 34.4 0.1 6.9e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG42910.1 - 3.9e-06 27.1 0.0 6.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG42910.1 - 1.8e-05 25.0 0.2 2.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGG42910.1 - 8.4e-05 22.2 0.7 0.00082 19.0 0.3 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase F420_ligase PF01996.11 EGG42911.1 - 9.9e-68 227.6 0.6 1.1e-67 227.4 0.4 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase PHP_C PF13263.1 EGG42912.1 - 5.5e-10 38.5 0.0 1.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 PHP-associated PHP PF02811.14 EGG42912.1 - 0.022 14.5 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 PHP domain DUF1933 PF09147.5 EGG42912.1 - 0.033 13.6 0.1 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) EF-hand_2 PF09068.6 EGG42912.1 - 0.043 13.8 2.1 0.13 12.3 1.5 1.9 1 1 0 1 1 1 0 EF hand Trypsin_2 PF13365.1 EGG42913.1 - 1.7e-20 73.1 0.4 4.4e-20 71.8 0.3 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGG42913.1 - 5e-15 55.6 4.5 7.1e-15 55.1 0.3 2.3 1 1 1 2 2 2 1 Trypsin PDZ_2 PF13180.1 EGG42913.1 - 1.1e-14 54.0 1.2 3.4e-14 52.4 0.3 2.3 2 0 0 2 2 2 1 PDZ domain Hemagglutinin PF00509.13 EGG42913.1 - 0.014 13.5 0.9 0.018 13.1 0.6 1.1 1 0 0 1 1 1 0 Haemagglutinin Peptidase_S29 PF02907.10 EGG42913.1 - 0.015 14.8 0.6 0.04 13.4 0.0 2.1 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease PDZ PF00595.19 EGG42913.1 - 0.021 14.9 2.0 16 5.7 0.8 3.8 2 1 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 EGG42913.1 - 0.12 10.7 2.3 0.11 10.9 0.3 1.8 2 0 0 2 2 2 0 Peptidase S46 CemA PF03040.9 EGG42913.1 - 0.13 11.8 2.3 0.19 11.2 1.6 1.2 1 0 0 1 1 1 0 CemA family TusA PF01206.12 EGG42914.1 - 3.4e-22 77.8 0.0 3.8e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA PALP PF00291.20 EGG42915.1 - 2e-57 194.7 0.0 2.5e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CCDC155 PF14662.1 EGG42916.1 - 0.00011 21.8 6.1 0.00015 21.3 4.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Ax_dynein_light PF10211.4 EGG42916.1 - 1.1 9.1 7.8 0.19 11.5 1.5 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DUF972 PF06156.8 EGG42916.1 - 1.5 9.1 7.5 1.8 8.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) zf-C2HC_2 PF13913.1 EGG42917.1 - 0.011 15.3 0.2 0.011 15.3 0.2 2.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C3HC4 PF00097.20 EGG42917.1 - 0.02 14.5 2.2 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG42917.1 - 0.024 14.3 2.1 2.1 8.1 0.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGG42917.1 - 0.027 14.4 1.1 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG42917.1 - 0.14 12.0 1.4 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-DBF PF07535.7 EGG42917.1 - 0.75 9.5 3.7 0.7 9.6 0.2 2.1 2 0 0 2 2 2 0 DBF zinc finger Response_reg PF00072.19 EGG42918.1 - 2.6e-14 53.1 0.2 2.9e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF4138 PF13595.1 EGG42918.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4138) DUF1059 PF06348.6 EGG42919.1 - 3.2e-13 49.2 0.6 3.4e-13 49.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Pyr_redox_2 PF07992.9 EGG42920.1 - 1.2e-30 106.9 6.8 4.1e-29 101.9 4.7 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG42920.1 - 2e-18 66.5 1.1 1.4e-16 60.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG42920.1 - 1.6e-13 51.2 0.2 8e-11 42.3 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG42920.1 - 1.3e-07 30.9 2.0 0.00031 19.7 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EGG42920.1 - 6.4e-07 28.5 2.1 0.0079 15.1 0.0 3.4 3 1 0 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.1 EGG42920.1 - 4.2e-06 25.9 0.1 0.046 12.6 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EGG42920.1 - 0.00012 21.2 0.0 0.0036 16.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EGG42920.1 - 0.00022 20.4 0.7 0.22 10.5 0.0 2.7 2 1 1 3 3 3 2 FAD binding domain FAD_binding_2 PF00890.19 EGG42920.1 - 0.00097 18.0 4.3 0.0078 15.1 0.1 3.4 2 1 2 4 4 4 1 FAD binding domain FAD_oxidored PF12831.2 EGG42920.1 - 0.0024 16.9 0.1 0.0046 16.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG42920.1 - 0.0059 16.6 0.2 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGG42920.1 - 0.0062 15.0 2.2 0.15 10.4 0.0 3.0 3 1 1 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.7 EGG42920.1 - 0.0066 15.4 0.4 0.91 8.3 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EGG42920.1 - 0.0068 16.6 0.5 0.051 13.8 0.1 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EGG42920.1 - 0.01 15.6 6.2 0.71 9.6 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding XdhC_C PF13478.1 EGG42920.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain MAS20 PF02064.10 EGG42920.1 - 0.13 12.1 0.2 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor ATP-cone PF03477.11 EGG42922.1 - 4.3e-08 33.4 0.1 1.2e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 ATP cone domain NERD PF08378.6 EGG42922.1 - 0.0061 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Nuclease-related domain Thi4 PF01946.12 EGG42924.1 - 2.3e-64 216.6 0.1 2.7e-64 216.4 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGG42924.1 - 8.5e-14 51.2 0.3 8.5e-07 28.1 0.0 2.9 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 EGG42924.1 - 4.4e-10 39.2 0.0 6.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EGG42924.1 - 3.4e-09 36.0 0.1 2.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG42924.1 - 1.8e-07 31.0 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGG42924.1 - 2.9e-07 30.5 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG42924.1 - 2.4e-06 26.3 0.0 3.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EGG42924.1 - 2.9e-06 26.6 0.0 4.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EGG42924.1 - 5e-05 22.3 0.1 0.00037 19.5 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGG42924.1 - 0.0002 21.4 0.1 0.00036 20.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGG42924.1 - 0.00024 20.0 0.1 0.0004 19.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EGG42924.1 - 0.0048 15.5 0.0 1 7.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EGG42924.1 - 0.0095 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EGG42924.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GDI PF00996.13 EGG42924.1 - 0.021 13.1 0.0 0.034 12.4 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 EGG42924.1 - 0.033 14.5 0.1 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EGG42924.1 - 0.099 12.7 0.0 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_7 PF13241.1 EGG42924.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EGG42924.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF95 PF01944.12 EGG42925.1 - 6.8e-07 29.0 15.5 7.7e-07 28.9 10.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF95 NIR_SIR PF01077.17 EGG42926.1 - 2e-41 140.9 0.0 4e-30 104.2 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EGG42926.1 - 4.6e-30 103.0 0.0 2.2e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Rhodanese PF00581.15 EGG42927.1 - 5.1e-39 133.1 0.0 1e-18 67.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain TPR_11 PF13414.1 EGG42928.1 - 4.2e-21 74.3 3.5 1.6e-10 40.4 0.0 3.4 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EGG42928.1 - 7.6e-20 69.1 6.5 7.9e-07 28.5 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGG42928.1 - 1.1e-18 65.9 8.1 8.3e-07 28.3 0.1 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGG42928.1 - 2.6e-16 59.8 0.1 2.5e-07 31.1 0.0 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG42928.1 - 8.6e-14 50.5 0.4 0.002 18.2 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGG42928.1 - 4e-13 49.4 3.2 6.1e-08 32.8 0.1 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG42928.1 - 4.2e-13 49.0 4.3 7.8e-05 22.5 0.4 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGG42928.1 - 3e-10 39.7 1.4 0.021 15.4 0.0 5.1 4 1 2 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGG42928.1 - 8.4e-10 37.7 4.7 0.00068 19.2 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG42928.1 - 1.6e-07 31.3 0.7 5.7e-07 29.5 0.1 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGG42928.1 - 2.2e-06 27.4 0.0 0.00027 20.7 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG42928.1 - 2.3e-06 27.3 0.2 0.093 12.6 0.0 3.8 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EGG42928.1 - 1.6e-05 24.6 0.2 1.2 9.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG42928.1 - 0.00016 21.8 5.4 2.1 9.0 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG42928.1 - 0.00027 20.5 0.5 8.6 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_27 PF13463.1 EGG42928.1 - 0.0064 16.7 0.2 0.022 15.0 0.1 1.9 1 0 0 1 1 1 1 Winged helix DNA-binding domain NARP1 PF12569.3 EGG42928.1 - 0.0092 14.7 2.8 0.69 8.5 0.0 2.6 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 Coatomer_E PF04733.9 EGG42928.1 - 0.011 14.9 2.7 0.063 12.4 0.1 2.9 2 1 3 5 5 5 0 Coatomer epsilon subunit TPR_20 PF14561.1 EGG42928.1 - 0.026 14.6 2.3 1.4 9.0 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat FAM180 PF15173.1 EGG42928.1 - 0.027 14.2 0.5 6 6.6 0.0 2.8 3 0 0 3 3 3 0 FAM180 family GCOM2 PF15328.1 EGG42928.1 - 0.059 13.1 1.0 0.11 12.2 0.1 1.7 2 1 0 2 2 1 0 Putative GRINL1B complex locus protein 2 DUF1840 PF08895.6 EGG42928.1 - 0.12 12.4 1.9 4.4 7.3 0.2 3.0 3 1 0 3 3 2 0 Domain of unknown function (DUF1840) TPR_3 PF07720.7 EGG42928.1 - 0.22 11.3 5.5 12 5.8 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps4_C PF09336.5 EGG42928.1 - 0.3 10.9 1.9 0.31 10.9 0.0 2.0 3 0 0 3 3 1 0 Vps4 C terminal oligomerisation domain Ferritin PF00210.19 EGG42928.1 - 0.66 9.7 5.4 1.5 8.5 0.3 3.2 3 0 0 3 3 3 0 Ferritin-like domain DUF4363 PF14276.1 EGG42928.1 - 1.3 8.6 6.5 0.97 9.1 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) Radical_SAM PF04055.16 EGG42929.1 - 7.5e-09 35.9 0.1 1.3e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TIM-br_sig_trns PF09370.5 EGG42929.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein HTH_11 PF08279.7 EGG42929.1 - 0.1 12.2 0.0 0.34 10.5 0.0 1.9 1 0 0 1 1 1 0 HTH domain HTH_45 PF14947.1 EGG42930.1 - 0.016 15.0 0.3 0.027 14.3 0.2 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix Radical_SAM PF04055.16 EGG42931.1 - 3.4e-12 46.8 0.0 8.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.8 EGG42931.1 - 0.0013 18.5 0.1 0.0037 17.0 0.1 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain SpoU_sub_bind PF08032.7 EGG42931.1 - 0.031 14.4 0.0 6.8 6.9 0.0 3.6 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding Ish1 PF10281.4 EGG42931.1 - 0.096 12.7 0.4 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Trypsin_2 PF13365.1 EGG42932.1 - 1.2e-21 76.8 0.2 2.5e-21 75.8 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGG42932.1 - 2.8e-15 56.4 0.7 1.5e-14 54.1 0.1 2.3 2 1 0 2 2 2 1 Trypsin PDZ_2 PF13180.1 EGG42932.1 - 4e-13 49.0 4.9 5.1e-13 48.7 0.5 2.7 2 1 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.10 EGG42932.1 - 0.0036 16.8 0.1 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.4 EGG42932.1 - 0.0081 14.6 1.1 0.014 13.8 0.2 1.6 2 0 0 2 2 2 1 Peptidase S46 PDZ PF00595.19 EGG42932.1 - 0.019 15.1 1.2 3.3 7.9 0.3 3.2 3 0 0 3 3 3 0 PDZ domain (Also known as DHR or GLGF) Peptidase_S32 PF05579.8 EGG42932.1 - 0.032 13.1 2.7 6.3 5.6 1.9 2.3 1 1 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Syndecan PF01034.15 EGG42932.1 - 0.069 12.8 1.3 0.14 11.8 0.9 1.4 1 0 0 1 1 1 0 Syndecan domain Peptidase_S7 PF00949.16 EGG42932.1 - 0.13 11.6 4.0 0.25 10.7 0.7 2.4 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Glycos_transf_2 PF00535.21 EGG42933.1 - 1.8e-30 105.8 0.1 2.5e-30 105.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGG42933.1 - 1.7e-20 73.8 0.0 2.5e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGG42933.1 - 7e-10 38.4 0.2 1.1e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGG42933.1 - 6.9e-09 35.2 0.0 1.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EGG42933.1 - 8.2e-05 22.8 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7N PF13733.1 EGG42933.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 HILPDA PF15220.1 EGG42933.1 - 0.3 11.1 1.4 0.89 9.5 0.0 2.5 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated Polyketide_cyc2 PF10604.4 EGG42934.1 - 9.9e-10 38.7 0.0 1.1e-09 38.6 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EGG42934.1 - 2e-05 24.6 0.0 2.5e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 EGG42934.1 - 0.0048 16.9 0.1 0.0056 16.7 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF493 PF04359.9 EGG42934.1 - 0.022 15.1 0.1 0.04 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF493) DUF16 PF01519.11 EGG42934.1 - 0.28 11.4 3.2 0.48 10.6 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 tRNA_bind PF01588.15 EGG42936.1 - 1e-22 79.7 0.0 1.2e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain TBP PF00352.16 EGG42937.1 - 2e-61 203.3 0.0 2.5e-30 103.6 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGG42937.1 - 7.1e-07 29.2 0.0 0.00052 20.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF1512 PF07431.7 EGG42938.1 - 3.3e-100 335.3 4.3 3.6e-100 335.1 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) Peptidase_M24 PF00557.19 EGG42939.1 - 7.3e-40 136.7 1.5 2.8e-39 134.8 1.0 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.11 EGG42939.1 - 0.055 13.8 1.5 3.9 7.9 0.1 2.9 3 0 0 3 3 3 0 ATP cone domain ApbE PF02424.10 EGG42939.1 - 0.056 12.7 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 ApbE family Sp100 PF03172.8 EGG42939.1 - 0.075 13.0 0.1 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Sp100 domain Tn7_Tnp_TnsA_C PF08721.6 EGG42939.1 - 0.08 12.9 0.0 2.7 8.0 0.0 3.0 3 1 0 3 3 3 0 TnsA endonuclease C terminal DUF955 PF06114.8 EGG42940.1 - 0.055 13.1 0.4 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Response_reg PF00072.19 EGG42941.1 - 9.4e-22 77.1 1.9 1.8e-21 76.2 0.6 2.1 2 0 0 2 2 2 1 Response regulator receiver domain TrmB PF01978.14 EGG42941.1 - 1.8e-14 53.1 0.0 5.7e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.3 EGG42941.1 - 1.7e-05 23.9 1.1 2.9e-05 23.1 0.4 1.6 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB HATPase_c PF02518.21 EGG42942.1 - 2.5e-22 78.6 0.0 5.5e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.20 EGG42942.1 - 1.1e-11 44.7 0.0 7.4e-11 42.0 0.0 2.4 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.1 EGG42942.1 - 1.1e-09 37.8 0.8 1.9e-08 33.8 0.0 2.9 2 1 1 3 3 3 1 GHKL domain 4HB_MCP_1 PF12729.2 EGG42942.1 - 1.2e-09 37.7 12.6 1.2e-09 37.7 8.7 3.2 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction HisKA PF00512.20 EGG42942.1 - 1.4e-08 34.6 0.6 3.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EGG42942.1 - 0.0017 18.0 0.1 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TarH PF02203.10 EGG42942.1 - 0.078 12.8 1.6 0.3 10.9 0.6 2.3 1 1 0 1 1 1 0 Tar ligand binding domain homologue Syntaxin-6_N PF09177.6 EGG42942.1 - 0.39 11.1 6.5 1.4 9.3 0.1 3.7 4 0 0 4 4 4 0 Syntaxin 6, N-terminal MCPsignal PF00015.16 EGG42942.1 - 0.64 9.5 5.3 0.62 9.5 0.4 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4446 PF14584.1 EGG42942.1 - 0.66 9.7 6.4 0.36 10.6 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4446) Ribosomal_L29 PF00831.18 EGG42942.1 - 1.4 8.6 4.2 6.6 6.5 0.1 3.2 3 0 0 3 3 3 0 Ribosomal L29 protein DUF2884 PF11101.3 EGG42942.1 - 4.5 6.5 7.9 0.27 10.5 1.4 2.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2884) Chorismate_synt PF01264.16 EGG42943.1 - 2.1e-139 463.8 0.2 2.4e-139 463.6 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase EAF PF09816.4 EGG42943.1 - 0.13 12.2 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription elongation factor HATPase_c PF02518.21 EGG42944.1 - 2.2e-16 59.5 0.0 4.6e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EGG42944.1 - 3.2e-13 49.9 0.0 6.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 EGG42944.1 - 9.8e-09 35.0 0.2 2.2e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EGG42944.1 - 2.2e-07 30.5 0.5 6e-07 29.0 0.0 2.0 3 0 0 3 3 3 1 GHKL domain PAS PF00989.19 EGG42944.1 - 0.00021 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EGG42944.1 - 0.00044 20.2 0.0 0.00088 19.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EGG42944.1 - 0.0016 18.4 0.0 0.0034 17.4 0.0 1.6 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EGG42944.1 - 0.11 12.4 0.1 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 PAS domain EPSP_synthase PF00275.15 EGG42945.1 - 7.7e-102 340.8 0.0 9.5e-102 340.5 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GHMP_kinases_N PF00288.21 EGG42946.1 - 2e-11 43.7 0.4 4e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGG42946.1 - 1.4e-05 25.1 0.1 0.00035 20.7 0.0 2.5 1 1 1 2 2 2 1 GHMP kinases C terminal RNase_PH PF01138.16 EGG42946.1 - 0.05 13.9 1.2 0.091 13.0 0.8 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Shikimate_dh_N PF08501.6 EGG42947.1 - 2.3e-28 98.0 0.0 5.7e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGG42947.1 - 3.6e-16 59.5 0.5 5.4e-16 58.9 0.4 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EGG42947.1 - 6.6e-06 25.3 1.2 1e-05 24.7 0.9 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EGG42947.1 - 0.0078 16.6 0.5 0.013 15.8 0.3 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EGG42947.1 - 0.012 15.8 0.3 0.025 14.8 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DHquinase_I PF01487.10 EGG42948.1 - 1.4e-56 191.6 0.2 1.6e-56 191.4 0.1 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase Beta-Casp PF10996.3 EGG42948.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Beta-Casp domain DHQS PF01959.11 EGG42949.1 - 4.9e-113 377.4 1.4 6e-113 377.1 1.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase (EC 4.6.1.3) Orthopox_A36R PF05950.6 EGG42949.1 - 0.039 13.8 0.2 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus A36R protein DeoC PF01791.4 EGG42950.1 - 8e-48 162.7 0.0 9.7e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Radical_SAM PF04055.16 EGG42951.1 - 7e-14 52.3 0.0 9.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily UbiD PF01977.11 EGG42952.1 - 2.7e-153 510.2 0.1 3.1e-153 510.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Parecho_VpG PF06344.6 EGG42954.1 - 0.0022 17.8 6.1 1.1 9.2 0.4 3.6 2 0 0 2 2 2 2 Parechovirus Genome-linked protein Ribosomal_L29 PF00831.18 EGG42954.1 - 0.015 14.9 1.2 0.015 14.9 0.8 1.8 2 0 0 2 2 2 0 Ribosomal L29 protein ERM PF00769.14 EGG42954.1 - 0.64 9.5 16.0 0.094 12.2 4.1 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Striatin PF08232.7 EGG42954.1 - 3.6 7.8 14.7 0.57 10.4 1.9 2.3 2 0 0 2 2 2 0 Striatin family AhpC-TSA PF00578.16 EGG42955.1 - 2.2e-40 137.2 0.3 2.5e-40 136.9 0.2 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG42955.1 - 8.8e-27 93.4 0.1 1e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGG42955.1 - 4e-08 33.1 0.1 7.6e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 EGG42955.1 - 1.1e-07 31.5 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.9 EGG42955.1 - 0.00059 19.5 1.5 0.0025 17.4 1.0 1.8 1 1 0 1 1 1 1 SCO1/SenC GSHPx PF00255.14 EGG42955.1 - 0.054 12.8 0.1 0.31 10.4 0.0 2.0 1 1 1 2 2 2 0 Glutathione peroxidase zf-C2H2_3 PF13878.1 EGG42955.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO MIP PF00230.15 EGG42956.1 - 4.8e-54 183.2 18.6 5.7e-54 182.9 12.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ldr_toxin PF13940.1 EGG42956.1 - 0.00062 19.4 0.4 0.0021 17.7 0.3 1.9 1 0 0 1 1 1 1 Toxin Ldr, type I toxin-antitoxin system NPV_P10 PF05531.7 EGG42957.1 - 0.00055 20.1 0.9 0.00067 19.8 0.7 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein MtrG PF04210.8 EGG42957.1 - 0.0085 15.7 1.8 0.014 15.0 0.6 1.7 1 1 1 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, subunit G Viral_P18 PF04521.8 EGG42957.1 - 0.013 14.9 1.9 0.013 14.9 1.3 1.4 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein IncA PF04156.9 EGG42957.1 - 0.017 14.7 7.9 0.034 13.7 5.5 1.5 1 1 0 1 1 1 0 IncA protein Nup54 PF13874.1 EGG42957.1 - 0.022 14.4 3.1 0.024 14.3 2.1 1.0 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 GAS PF13851.1 EGG42957.1 - 0.032 13.4 13.3 0.035 13.2 9.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TipAS PF07739.8 EGG42957.1 - 0.042 14.1 4.1 0.062 13.6 2.0 1.7 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain BLOC1_2 PF10046.4 EGG42957.1 - 0.058 13.5 7.6 0.1 12.7 5.2 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Toxin_52 PF15605.1 EGG42957.1 - 0.068 13.0 4.1 0.086 12.7 2.8 1.1 1 0 0 1 1 1 0 Putative toxin 52 TMF_TATA_bd PF12325.3 EGG42957.1 - 0.078 12.7 8.4 0.12 12.1 5.8 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FadA PF09403.5 EGG42957.1 - 0.086 12.8 11.3 0.11 12.4 7.9 1.2 1 0 0 1 1 1 0 Adhesion protein FadA Spc7 PF08317.6 EGG42957.1 - 0.094 11.3 8.7 0.13 10.8 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EGG42957.1 - 0.099 12.6 7.9 0.12 12.3 5.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 EGG42957.1 - 0.1 12.5 8.4 0.12 12.3 5.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.3 EGG42957.1 - 0.11 9.8 8.1 0.12 9.7 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Dor1 PF04124.7 EGG42957.1 - 0.11 10.8 4.8 0.13 10.6 3.3 1.1 1 0 0 1 1 1 0 Dor1-like family DUF1690 PF07956.6 EGG42957.1 - 0.12 12.3 9.2 0.13 12.1 6.3 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) MscS_porin PF12795.2 EGG42957.1 - 0.12 11.6 7.0 0.13 11.5 4.8 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain YkyA PF10368.4 EGG42957.1 - 0.13 11.6 14.0 0.15 11.3 9.7 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Vps5 PF09325.5 EGG42957.1 - 0.13 11.4 7.3 0.22 10.7 5.0 1.4 1 1 0 1 1 1 0 Vps5 C terminal like HALZ PF02183.13 EGG42957.1 - 0.19 11.4 11.0 0.059 13.0 2.9 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper FAM178 PF14816.1 EGG42957.1 - 0.2 10.3 8.6 0.21 10.2 6.0 1.0 1 0 0 1 1 1 0 Family of unknown function, FAM178 FlxA PF14282.1 EGG42957.1 - 0.22 11.4 7.6 0.67 9.9 5.2 1.7 1 1 0 1 1 1 0 FlxA-like protein DUF883 PF05957.8 EGG42957.1 - 0.26 11.7 2.4 0.41 11.0 1.7 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4446 PF14584.1 EGG42957.1 - 0.28 10.9 5.6 0.32 10.8 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMF_DNA_bd PF12329.3 EGG42957.1 - 0.29 10.9 11.2 0.47 10.3 7.6 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2951 PF11166.3 EGG42957.1 - 0.32 10.8 10.7 0.36 10.7 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) K-box PF01486.12 EGG42957.1 - 0.41 10.4 7.8 0.46 10.3 2.2 2.1 1 1 1 2 2 2 0 K-box region Vir_act_alpha_C PF10400.4 EGG42957.1 - 0.43 10.9 4.0 0.26 11.6 0.2 1.9 1 1 1 2 2 2 0 Virulence activator alpha C-term Cir_Bir_Yir PF06022.6 EGG42957.1 - 0.44 9.7 9.4 0.46 9.6 6.5 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Syntaxin_2 PF14523.1 EGG42957.1 - 0.47 10.4 7.8 2.9 7.9 0.2 2.1 1 1 1 2 2 2 0 Syntaxin-like protein APG6 PF04111.7 EGG42957.1 - 0.48 9.4 12.3 0.54 9.2 8.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF349 PF03993.7 EGG42957.1 - 0.48 10.6 6.6 0.5 10.5 3.5 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Fib_alpha PF08702.5 EGG42957.1 - 0.52 10.4 4.6 0.41 10.7 2.4 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EGG42957.1 - 0.55 10.1 2.7 1.4 8.8 1.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4441 PF14536.1 EGG42957.1 - 0.58 10.1 8.5 0.73 9.8 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Occludin_ELL PF07303.8 EGG42957.1 - 0.58 10.9 9.6 0.73 10.5 6.7 1.2 1 0 0 1 1 1 0 Occludin homology domain RNA_pol_Rpb1_6 PF04992.9 EGG42957.1 - 0.59 9.8 6.6 0.75 9.5 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Synaptonemal_3 PF15191.1 EGG42957.1 - 0.59 9.8 4.3 0.54 10.0 1.1 1.9 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 Sec5 PF15469.1 EGG42957.1 - 0.63 9.7 7.7 0.92 9.2 5.4 1.4 1 1 0 1 1 1 0 Exocyst complex component Sec5 DUF3245 PF11595.3 EGG42957.1 - 0.73 10.1 7.8 0.88 9.8 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) LUC7 PF03194.10 EGG42957.1 - 0.74 9.2 7.3 0.74 9.2 5.1 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Myb_DNA-bind_4 PF13837.1 EGG42957.1 - 0.76 9.9 5.5 1.6 8.9 3.8 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3818 PF12825.2 EGG42957.1 - 0.77 8.3 5.5 0.91 8.1 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) TBPIP PF07106.8 EGG42957.1 - 0.9 9.0 10.7 1.6 8.2 7.4 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 EGG42957.1 - 0.95 8.9 10.1 2.5 7.6 1.4 2.1 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 EGG42957.1 - 0.97 7.2 8.2 0.96 7.2 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1706 PF08020.6 EGG42957.1 - 1 8.8 6.6 9.2 5.7 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1706) DUF904 PF06005.7 EGG42957.1 - 1.1 9.5 12.7 4.8 7.5 8.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Phage_GP20 PF06810.6 EGG42957.1 - 1.2 8.5 14.1 1.7 8.0 9.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DASH_Dad3 PF08656.5 EGG42957.1 - 1.3 8.7 5.6 6.5 6.5 3.9 1.9 1 1 0 1 1 1 0 DASH complex subunit Dad3 DUF4140 PF13600.1 EGG42957.1 - 1.4 9.4 4.1 3.7 8.0 0.7 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) MutS_IV PF05190.13 EGG42957.1 - 1.7 8.8 9.0 0.77 9.9 0.9 2.1 2 0 0 2 2 2 0 MutS family domain IV DUF106 PF01956.11 EGG42957.1 - 1.7 8.1 7.1 1.8 8.1 4.9 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 GLE1 PF07817.8 EGG42957.1 - 1.8 7.4 5.4 1.9 7.3 3.7 1.0 1 0 0 1 1 1 0 GLE1-like protein DUF922 PF06037.6 EGG42957.1 - 2 7.7 5.5 2.2 7.5 3.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) DUF972 PF06156.8 EGG42957.1 - 2.1 8.7 8.7 2.7 8.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EGG42957.1 - 2.2 7.9 11.3 1.4 8.6 1.8 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3450 PF11932.3 EGG42957.1 - 2.5 7.2 5.8 2.9 7.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 EGG42957.1 - 2.8 6.2 10.0 3.6 5.9 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YtxH PF12732.2 EGG42957.1 - 2.9 8.3 8.1 36 4.8 5.6 2.0 1 1 0 1 1 1 0 YtxH-like protein CotJB PF12652.2 EGG42957.1 - 3 7.9 6.0 6.8 6.8 1.2 2.1 1 1 1 2 2 2 0 CotJB protein DUF3847 PF12958.2 EGG42957.1 - 4.6 7.0 8.5 30 4.4 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) DUF2312 PF10073.4 EGG42957.1 - 5.1 6.5 7.6 5.8 6.3 1.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) FemAB PF02388.11 EGG42957.1 - 6.2 5.3 9.7 6.4 5.3 6.7 1.1 1 0 0 1 1 1 0 FemAB family DUF1910 PF08928.5 EGG42957.1 - 6.4 6.8 9.0 0.68 9.9 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) HJURP_C PF12347.3 EGG42957.1 - 7 6.3 12.1 9.3 5.9 3.0 2.4 1 1 1 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF1227 PF06777.6 EGG42957.1 - 7.1 6.3 8.5 3.3 7.4 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1227) FTCD_C PF04961.7 EGG42957.1 - 7.4 5.9 6.2 5.6 6.3 1.4 1.9 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Ax_dynein_light PF10211.4 EGG42957.1 - 8.8 6.1 11.4 11 5.8 7.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain TMPIT PF07851.8 EGG42957.1 - 9.4 5.1 8.5 11 5.0 5.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein DLH PF01738.13 EGG42958.1 - 5.2e-51 173.0 0.0 7e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGG42958.1 - 5.4e-18 65.1 0.0 9e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG42958.1 - 1e-07 32.1 0.0 2.3e-06 27.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGG42958.1 - 3.3e-07 29.7 0.0 0.013 14.7 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 EGG42958.1 - 1.5e-05 23.9 0.0 2.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.6 EGG42958.1 - 6e-05 22.8 0.2 0.0037 16.9 0.0 2.4 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 EGG42958.1 - 9.8e-05 21.3 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EGG42958.1 - 0.0038 16.8 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 EGG42958.1 - 0.1 10.8 0.0 0.32 9.2 0.0 1.7 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II UMPH-1 PF05822.7 EGG42959.1 - 0.055 12.7 0.3 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF4396 PF14342.1 EGG42959.1 - 0.23 11.5 2.5 0.15 12.1 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4396) DUF443 PF04276.7 EGG42959.1 - 0.32 10.3 8.1 1.8 7.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF443) P5-ATPase PF12409.3 EGG42959.1 - 1.2 8.9 6.1 0.15 11.9 0.5 2.1 2 1 0 2 2 2 0 P5-type ATPase cation transporter SPC25 PF06703.6 EGG42959.1 - 1.4 8.5 6.0 0.12 11.9 0.8 1.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Polysacc_synt_C PF14667.1 EGG42959.1 - 2 8.2 11.2 16 5.2 7.9 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PDR_CDR PF06422.7 EGG42959.1 - 3.3 7.4 5.1 0.62 9.7 0.4 2.0 2 1 1 3 3 3 0 CDR ABC transporter TctB PF07331.6 EGG42959.1 - 9.5 5.8 7.5 7.6 6.1 2.2 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Adenine_glyco PF03352.8 EGG42960.1 - 3.7e-83 277.4 0.4 4.4e-83 277.2 0.3 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Ferritin PF00210.19 EGG42961.1 - 4.8e-39 133.3 1.1 5.6e-39 133.1 0.8 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 EGG42961.1 - 3.1e-06 27.5 1.1 4e-06 27.1 0.7 1.2 1 0 0 1 1 1 1 Rubrerythrin Lipoprotein_10 PF03202.8 EGG42961.1 - 0.018 15.0 0.6 0.051 13.6 0.4 1.7 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region RTX_C PF08339.5 EGG42961.1 - 5.1 6.8 6.5 3.2 7.4 2.2 2.3 2 1 0 2 2 2 0 RTX C-terminal domain DUF3990 PF13151.1 EGG42964.1 - 0.041 13.2 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Metallothio_Euk PF12749.2 EGG42965.1 - 0.19 11.8 7.3 0.21 11.6 5.0 1.1 1 0 0 1 1 1 0 Eukaryotic metallothionein zf-RING-like PF08746.6 EGG42965.1 - 0.43 10.6 10.7 0.54 10.3 7.4 1.1 1 0 0 1 1 1 0 RING-like domain MscS_porin PF12795.2 EGG42966.1 - 0.00054 19.3 29.9 0.00074 18.9 10.4 3.1 2 1 1 3 3 3 2 Mechanosensitive ion channel porin domain WEMBL PF05701.6 EGG42966.1 - 0.00081 17.9 47.2 0.044 12.2 20.7 2.1 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Vps5 PF09325.5 EGG42966.1 - 0.0037 16.5 11.5 0.0037 16.5 7.9 3.2 2 1 1 3 3 3 2 Vps5 C terminal like Filament PF00038.16 EGG42966.1 - 0.0038 16.7 11.7 0.0038 16.7 8.1 3.4 1 1 2 3 3 3 1 Intermediate filament protein Streptin-Immun PF11083.3 EGG42966.1 - 0.0039 17.1 32.1 0.22 11.5 2.0 4.4 2 1 2 4 4 4 4 Lantibiotic streptin immunity protein DUF948 PF06103.6 EGG42966.1 - 0.0048 16.7 3.9 0.0048 16.7 2.7 3.6 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EGG42966.1 - 0.054 12.6 11.8 0.015 14.5 1.8 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF3407 PF11887.3 EGG42966.1 - 0.12 11.6 2.5 0.78 8.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3407) DUF3584 PF12128.3 EGG42966.1 - 0.14 9.4 39.2 0.19 8.9 27.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 EGG42966.1 - 0.23 9.6 42.4 0.32 9.1 29.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) EzrA PF06160.7 EGG42966.1 - 0.31 9.1 43.4 0.1 10.7 9.3 3.1 1 1 1 3 3 3 0 Septation ring formation regulator, EzrA IncA PF04156.9 EGG42966.1 - 0.44 10.1 46.9 1.4 8.4 6.5 3.1 1 1 2 3 3 3 0 IncA protein Spc7 PF08317.6 EGG42966.1 - 1.7 7.1 47.0 0.67 8.5 19.9 2.9 1 1 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 EGG42966.1 - 2 8.1 34.5 0.44 10.2 8.8 3.2 1 1 2 3 3 3 0 Laminin Domain II Atg14 PF10186.4 EGG42966.1 - 2.1 7.1 40.9 24 3.7 4.4 3.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 COG2 PF06148.6 EGG42966.1 - 3.3 7.5 26.0 3.8 7.3 1.6 4.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1129 PF06570.6 EGG42967.1 - 0.14 11.4 0.8 0.16 11.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1049 PF06305.6 EGG42967.1 - 2.2 7.8 5.9 0.13 11.7 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) tRNA-synt_1f PF01921.13 EGG42968.1 - 1.3e-107 359.5 0.0 4.8e-107 357.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) PolyA_pol_RNAbd PF12627.2 EGG42968.1 - 0.02 14.4 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A tRNA-synt_1g PF09334.6 EGG42968.1 - 0.047 12.3 0.0 0.14 10.8 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (M) Radical_SAM PF04055.16 EGG42969.1 - 2.5e-20 73.2 0.5 5.8e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGG42969.1 - 1.7e-05 24.7 0.0 4.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGG42969.1 - 0.039 14.1 0.1 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Na_H_Exchanger PF00999.16 EGG42970.1 - 1.5e-65 221.2 49.6 2e-65 220.8 34.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AIRS_C PF02769.17 EGG42971.1 - 1.8e-25 89.7 0.0 3.4e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGG42971.1 - 9.6e-17 61.0 0.9 2.1e-16 59.8 0.6 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PAC2 PF09754.4 EGG42972.1 - 1.6e-31 109.8 0.0 1.9e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 PAC2 family Na_H_Exchanger PF00999.16 EGG42973.1 - 1.2e-37 129.3 47.0 1.7e-37 128.8 32.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sir1 PF11603.3 EGG42974.1 - 0.1 12.7 0.4 0.14 12.2 0.3 1.2 1 0 0 1 1 1 0 Regulatory protein Sir1 ATP_bind_4 PF01902.12 EGG42975.1 - 2.6e-58 196.9 0.2 2.9e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 ATP-binding region Asn_synthase PF00733.16 EGG42975.1 - 1.4e-06 28.0 0.1 2.8e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.8 EGG42975.1 - 0.021 14.1 0.0 0.059 12.6 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC SRP54 PF00448.17 EGG42976.1 - 6.4e-69 231.3 1.3 6.6e-69 231.2 0.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGG42976.1 - 1.1e-29 102.7 4.7 2.7e-29 101.4 0.7 2.9 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 EGG42976.1 - 5.8e-15 55.1 1.8 5.8e-15 55.1 1.2 2.0 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EGG42976.1 - 2.3e-10 40.1 0.2 6.5e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 EGG42976.1 - 8.2e-06 25.3 0.7 2.4e-05 23.8 0.5 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EGG42976.1 - 0.0001 21.9 0.5 0.0003 20.5 0.3 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EGG42976.1 - 0.00026 21.8 0.1 0.0012 19.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EGG42976.1 - 0.00035 20.0 2.1 0.6 9.5 0.3 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.5 EGG42976.1 - 0.00038 19.7 0.1 0.0011 18.2 0.0 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.11 EGG42976.1 - 0.00059 18.6 0.2 0.0029 16.4 0.2 2.2 1 1 0 1 1 1 1 ArgK protein 6PF2K PF01591.13 EGG42976.1 - 0.0006 18.9 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.1 EGG42976.1 - 0.0012 19.1 1.7 0.0089 16.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EGG42976.1 - 0.0013 18.3 0.4 0.0029 17.2 0.0 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EGG42976.1 - 0.0015 18.6 0.2 0.0057 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.1 EGG42976.1 - 0.0035 17.2 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 EGG42976.1 - 0.0038 16.4 0.1 0.01 15.0 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_33 PF13671.1 EGG42976.1 - 0.0055 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGG42976.1 - 0.0062 15.9 0.4 0.018 14.4 0.3 1.8 1 0 0 1 1 1 1 Thymidylate kinase LpxK PF02606.9 EGG42976.1 - 0.0088 15.0 0.2 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase ATP_bind_1 PF03029.12 EGG42976.1 - 0.015 14.8 0.1 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_26 PF13500.1 EGG42976.1 - 0.02 14.5 0.5 0.36 10.3 0.3 2.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGG42976.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mur_ligase_M PF08245.7 EGG42976.1 - 0.027 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Mur ligase middle domain SpoVIF PF14069.1 EGG42976.1 - 0.028 14.1 0.1 0.091 12.5 0.1 2.0 1 0 0 1 1 1 0 Stage VI sporulation protein F MipZ PF09140.6 EGG42976.1 - 0.029 13.4 0.5 0.69 8.9 0.3 2.2 1 1 0 1 1 1 0 ATPase MipZ AAA_30 PF13604.1 EGG42976.1 - 0.03 13.8 0.0 0.069 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EGG42976.1 - 0.032 13.4 0.3 0.22 10.7 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EGG42976.1 - 0.033 14.1 0.2 0.16 11.9 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EGG42976.1 - 0.035 13.5 1.0 0.18 11.1 0.2 2.1 1 1 1 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 EGG42976.1 - 0.038 13.6 1.5 0.057 13.1 0.2 2.0 2 0 0 2 2 1 0 NTPase GTP_EFTU PF00009.22 EGG42976.1 - 0.042 13.2 0.9 0.23 10.8 0.6 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EGG42976.1 - 0.043 13.2 1.2 0.62 9.4 0.8 2.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGG42976.1 - 0.05 13.9 0.2 0.14 12.4 0.0 1.9 2 0 0 2 2 1 0 ABC transporter DUF4317 PF14199.1 EGG42976.1 - 0.05 12.3 0.5 5.8 5.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) G-alpha PF00503.15 EGG42976.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.9 EGG42976.1 - 0.089 12.5 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EGG42976.1 - 0.092 12.9 0.2 2.1 8.5 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGG42976.1 - 0.15 11.9 0.3 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain THUMP PF02926.12 EGG42977.1 - 4.1e-06 26.7 0.1 9.3e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 THUMP domain DUF4046 PF13255.1 EGG42978.1 - 0.046 12.4 0.1 0.061 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) SprT-like PF10263.4 EGG42978.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Ribosomal_S27 PF01599.14 EGG42980.1 - 8.5e-19 67.1 5.6 1e-18 66.8 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a GCC2_GCC3 PF07699.8 EGG42980.1 - 0.00071 19.0 2.0 0.0011 18.5 1.4 1.2 1 0 0 1 1 1 1 GCC2 and GCC3 DUF1451 PF07295.6 EGG42980.1 - 0.0013 18.5 0.6 0.0013 18.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1451) DZR PF12773.2 EGG42980.1 - 0.0044 16.7 0.6 0.0059 16.4 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 EGG42980.1 - 0.0068 15.8 2.2 0.011 15.1 1.5 1.2 1 0 0 1 1 1 1 A2L zinc ribbon domain Ribosomal_L37e PF01907.14 EGG42980.1 - 0.013 15.2 3.6 0.021 14.5 2.5 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e GFA PF04828.9 EGG42980.1 - 0.031 14.2 2.5 0.081 12.8 0.1 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 EGG42980.1 - 0.036 13.5 2.6 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain NCD3G PF07562.9 EGG42980.1 - 0.039 13.6 0.6 0.05 13.3 0.4 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR C1_1 PF00130.17 EGG42980.1 - 0.048 13.4 1.3 0.065 12.9 0.9 1.1 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SprT-like PF10263.4 EGG42980.1 - 0.079 12.6 0.5 0.077 12.6 0.3 1.0 1 0 0 1 1 1 0 SprT-like family HypA PF01155.14 EGG42980.1 - 0.11 12.2 0.6 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EGG42980.1 - 0.15 11.2 5.6 0.84 8.9 0.3 2.1 1 1 1 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EGG42980.1 - 0.22 11.0 3.2 0.39 10.2 2.2 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit OrfB_Zn_ribbon PF07282.6 EGG42980.1 - 0.29 10.8 3.8 0.43 10.2 2.6 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 EGG42980.1 - 0.69 9.6 6.8 6.2 6.6 3.7 2.3 1 1 1 2 2 2 0 Nudix N-terminal zf-C2H2_3 PF13878.1 EGG42980.1 - 0.78 9.3 6.1 3.7 7.1 0.5 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Ribosomal_S24e PF01282.14 EGG42981.1 - 5.9e-05 22.7 0.3 8.5e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e GXGXG PF01493.14 EGG42981.1 - 0.011 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 GXGXG motif DUF309 PF03745.9 EGG42982.1 - 4.4e-17 61.2 0.1 6.6e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) PhosphMutase PF10143.4 EGG42983.1 - 2e-48 164.3 0.0 3.2e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 EGG42983.1 - 1.2e-31 110.0 1.2 1.8e-31 109.4 0.9 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EGG42983.1 - 0.00047 19.5 0.0 0.0053 16.1 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase GalP_UDP_transf PF01087.17 EGG42984.1 - 1.2e-10 41.7 0.0 5e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 EGG42984.1 - 0.00012 22.5 0.0 0.02 15.4 0.0 2.3 2 0 0 2 2 2 1 HIT domain GalP_UDP_tr_C PF02744.12 EGG42984.1 - 0.002 17.6 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 EGG42984.1 - 0.0082 16.3 0.0 0.054 13.7 0.0 2.1 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.11 EGG42985.1 - 4e-05 22.5 8.6 5.4e-05 22.0 6.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF956 PF06115.6 EGG42985.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF956) YesK PF14150.1 EGG42985.1 - 0.13 12.4 0.5 0.13 12.4 0.4 2.8 2 1 0 3 3 3 0 YesK-like protein IncFII_repA PF02387.10 EGG42985.1 - 0.19 10.8 0.2 0.24 10.5 0.2 1.1 1 0 0 1 1 1 0 IncFII RepA protein family MFS_2 PF13347.1 EGG42985.1 - 0.98 7.7 11.2 1.3 7.3 7.6 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein Claudin_2 PF13903.1 EGG42985.1 - 2 8.1 4.5 1.6 8.4 1.9 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2975 PF11188.3 EGG42985.1 - 6.5 6.4 11.5 3.3 7.4 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF2189 PF09955.4 EGG42985.1 - 6.7 6.6 10.3 14 5.5 6.1 2.2 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) NTP_transferase PF00483.18 EGG42986.1 - 3.6e-26 91.9 0.1 4e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGG42986.1 - 0.087 12.8 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Phos_pyr_kin PF08543.7 EGG42987.1 - 3.4e-73 245.8 1.1 3.4e-73 245.8 0.8 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Aldolase_2 PF10120.4 EGG42987.1 - 2.7e-54 183.0 0.1 4.2e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Putative aldolase PfkB PF00294.19 EGG42987.1 - 3.4e-12 46.1 0.0 4.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EGG42987.1 - 0.0073 15.6 0.2 0.015 14.5 0.2 1.5 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EGG42987.1 - 0.047 12.8 0.1 0.098 11.8 0.1 1.5 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family ThiC PF01964.13 EGG42988.1 - 1.8e-175 583.5 0.3 2.1e-175 583.3 0.2 1.0 1 0 0 1 1 1 1 ThiC family NUDIX PF00293.23 EGG42989.1 - 5.8e-11 42.1 0.0 6.5e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EGG42989.1 - 0.00062 19.1 0.2 0.0015 17.9 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain PDH PF02153.12 EGG42990.1 - 1.6e-25 89.4 0.2 1.9e-25 89.2 0.2 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.14 EGG42990.1 - 4.2e-06 26.0 0.1 7.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGG42990.1 - 9.9e-06 25.4 0.1 2.8e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGG42990.1 - 0.00052 19.7 0.1 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGG42990.1 - 0.00057 20.2 0.5 0.0078 16.6 0.0 3.0 2 2 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EGG42990.1 - 0.0021 17.8 0.9 0.65 9.7 0.1 2.9 2 2 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EGG42990.1 - 0.02 14.7 0.5 6.5 6.5 0.0 3.1 2 2 1 3 3 3 0 ThiF family IlvN PF07991.7 EGG42990.1 - 0.021 14.1 0.1 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF3150 PF11348.3 EGG42990.1 - 0.026 13.6 0.4 0.04 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Phage-tail_1 PF09097.5 EGG42990.1 - 0.036 13.6 1.1 0.086 12.3 0.3 1.7 1 1 0 2 2 2 0 Baseplate structural protein, domain 1 NmrA PF05368.8 EGG42990.1 - 0.05 12.8 1.2 0.51 9.5 0.0 2.6 3 1 0 3 3 3 0 NmrA-like family NAD_binding_10 PF13460.1 EGG42990.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EGG42990.1 - 0.094 12.6 0.1 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF155 PF02582.9 EGG42990.1 - 0.35 10.7 3.5 2.4 8.0 0.3 2.4 1 1 1 2 2 2 0 Uncharacterised ACR, YagE family COG1723 DUF3040 PF11239.3 EGG42992.1 - 0.029 14.4 0.5 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF202 PF02656.10 EGG42992.1 - 0.047 13.9 0.1 0.84 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF872 PF05915.7 EGG42992.1 - 0.084 12.7 0.4 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SdpI PF13630.1 EGG42992.1 - 0.1 12.3 4.8 0.29 10.8 0.7 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family YjgP_YjgQ PF03739.9 EGG42992.1 - 0.26 9.9 4.0 0.18 10.5 0.2 1.9 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family YtpI PF14007.1 EGG42992.1 - 1.4 8.9 7.0 0.13 12.1 1.0 2.0 2 0 0 2 2 2 0 YtpI-like protein DUF161 PF02588.10 EGG42992.1 - 8.6 6.7 11.2 19 5.6 2.5 2.6 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 tRNA_anti-codon PF01336.20 EGG42993.1 - 3.2e-06 26.9 0.2 4.1e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HupF_HypC PF01455.13 EGG42993.1 - 0.051 13.5 0.9 2.3 8.2 0.5 2.1 1 1 1 2 2 2 0 HupF/HypC family DUF4290 PF14123.1 EGG42994.1 - 0.007 15.5 1.1 0.012 14.8 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4290) ApoLp-III PF07464.6 EGG42994.1 - 0.014 15.4 4.5 0.052 13.5 2.0 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CHD5 PF04420.9 EGG42994.1 - 0.025 14.2 2.6 0.033 13.8 1.8 1.3 1 0 0 1 1 1 0 CHD5-like protein AATF-Che1 PF13339.1 EGG42994.1 - 0.038 14.1 1.1 0.091 12.9 0.8 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF2232 PF09991.4 EGG42994.1 - 0.085 11.8 0.9 0.11 11.4 0.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Phasin_2 PF09361.5 EGG42994.1 - 0.089 12.8 4.2 2.7 8.0 1.2 2.6 1 1 1 2 2 2 0 Phasin protein DUF2365 PF10157.4 EGG42994.1 - 0.089 12.6 1.1 6.6 6.6 0.0 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF643 PF04867.7 EGG42994.1 - 0.095 13.0 7.2 0.4 11.0 2.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF643) DivIVA PF05103.8 EGG42994.1 - 0.099 12.6 5.8 0.14 12.2 4.1 1.2 1 0 0 1 1 1 0 DivIVA protein Fmp27_GFWDK PF10347.4 EGG42994.1 - 0.11 12.4 3.1 1.1 9.1 0.9 2.1 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FAD-SLDH PF12318.3 EGG42994.1 - 0.12 12.0 1.1 0.31 10.7 0.3 1.7 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PhaP_Bmeg PF09602.5 EGG42994.1 - 0.17 11.6 6.0 0.39 10.5 4.1 1.7 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4456 PF14644.1 EGG42994.1 - 0.43 9.7 4.6 0.78 8.9 2.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4456) Phage_int_SAM_5 PF13102.1 EGG42994.1 - 0.86 9.6 5.9 3.8 7.5 4.0 1.8 1 1 0 1 1 1 0 Phage integrase SAM-like domain DUF148 PF02520.12 EGG42994.1 - 1.9 8.3 9.5 1.6 8.5 1.8 2.7 1 1 2 3 3 3 0 Domain of unknown function DUF148 YtxH PF12732.2 EGG42994.1 - 3.5 8.0 4.7 26 5.2 3.3 2.1 1 1 0 1 1 1 0 YtxH-like protein HD PF01966.17 EGG42996.1 - 3.3e-16 59.3 0.1 4.7e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 HD domain ClpS PF02617.12 EGG42996.1 - 0.044 13.4 0.3 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS zf-CCHC_4 PF14392.1 EGG42997.1 - 1.4 8.6 7.0 0.08 12.6 1.4 1.6 1 1 1 2 2 2 0 Zinc knuckle DUF2685 PF10886.3 EGG42997.1 - 2.5 8.1 4.9 16 5.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) Fer4_10 PF13237.1 EGG42997.1 - 2.6 7.9 7.1 1.8 8.4 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-FCS PF06467.9 EGG42997.1 - 5.5 6.7 10.2 3.2 7.4 0.3 2.5 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif TFIIB PF00382.14 EGG42998.1 - 1.7e-23 82.2 1.8 3.8e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG42998.1 - 0.0027 16.9 0.1 0.0054 16.0 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Rrf2 PF02082.15 EGG42998.1 - 0.0033 17.5 0.7 2.7 8.1 0.0 3.1 2 1 1 3 3 3 2 Transcriptional regulator Cyclin_C PF02984.14 EGG42998.1 - 0.0073 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain KIAA1430 PF13879.1 EGG42998.1 - 0.025 14.9 0.5 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 KIAA1430 homologue HTH_24 PF13412.1 EGG42998.1 - 0.057 12.8 1.2 0.44 9.9 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Pyridox_ox_2 PF12900.2 EGG42999.1 - 1.3e-07 31.5 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EGG42999.1 - 7.5e-06 25.8 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_8 PF13450.1 EGG43002.1 - 1.1e-14 54.1 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGG43002.1 - 5.3e-11 42.2 0.0 1.1e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGG43002.1 - 5.2e-09 35.4 0.0 0.00065 18.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EGG43002.1 - 9.1e-05 21.6 0.3 0.0047 16.0 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EGG43002.1 - 0.0002 21.4 0.1 0.056 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG43002.1 - 0.00062 20.1 0.7 0.05 14.0 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG43002.1 - 0.00067 18.2 0.1 0.19 10.1 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EGG43002.1 - 0.00081 18.3 0.1 0.031 13.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGG43002.1 - 0.0026 17.6 0.1 0.0068 16.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGG43002.1 - 0.0068 15.4 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EGG43002.1 - 0.0096 14.8 0.7 2 7.2 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Strep_67kDa_ant PF06100.6 EGG43002.1 - 0.022 13.1 0.4 2.3 6.4 0.1 2.2 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family UDPG_MGDP_dh_N PF03721.9 EGG43002.1 - 0.025 13.9 0.2 0.082 12.2 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 EGG43002.1 - 0.039 13.0 0.0 0.57 9.2 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase B12-binding_2 PF02607.12 EGG43003.1 - 3.4e-13 49.4 0.0 6.2e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.14 EGG43003.1 - 9.9e-12 44.7 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain NAD_binding_10 PF13460.1 EGG43004.1 - 1.1e-21 77.7 0.0 1.4e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGG43004.1 - 5.2e-12 45.7 0.0 4e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGG43004.1 - 8.1e-12 44.8 0.0 1.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EGG43004.1 - 6.6e-10 38.1 0.0 1.4e-09 37.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG43004.1 - 0.0021 17.0 0.0 0.0042 16.0 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGG43004.1 - 0.0021 17.0 0.7 0.013 14.4 0.1 2.4 2 1 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EGG43004.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EGG43004.1 - 0.038 12.8 0.8 0.22 10.3 0.6 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_7 PF03441.9 EGG43005.1 - 3.3e-96 321.7 1.7 4.7e-96 321.2 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGG43005.1 - 2.4e-38 131.4 0.0 4.2e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase OprF PF05736.6 EGG43005.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 OprF membrane domain DUF1722 PF08349.6 EGG43006.1 - 2.6e-32 111.1 1.2 3e-32 110.9 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) EF-hand_1 PF00036.27 EGG43007.1 - 0.031 13.5 0.1 6.5 6.3 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF1372 PF07116.6 EGG43007.1 - 0.058 13.3 0.2 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) Dioxygenase_N PF04444.9 EGG43007.1 - 0.24 11.4 0.8 20 5.2 0.0 2.7 3 0 0 3 3 3 0 Catechol dioxygenase N terminus Mgr1 PF08602.5 EGG43008.1 - 0.0089 15.0 1.3 0.011 14.8 0.9 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit DUF2833 PF11090.3 EGG43008.1 - 0.023 14.8 2.2 0.028 14.5 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2833) IMS PF00817.15 EGG43008.1 - 0.041 13.6 0.1 0.043 13.6 0.1 1.1 1 0 0 1 1 1 0 impB/mucB/samB family RNA_pol_Rpb4 PF03874.11 EGG43008.1 - 0.05 13.6 1.4 0.059 13.3 0.8 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb4 G6PD_N PF00479.17 EGG43008.1 - 0.078 13.2 0.6 0.087 13.0 0.4 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_S7e PF01251.13 EGG43008.1 - 0.079 12.4 0.8 0.1 12.0 0.5 1.3 1 1 0 1 1 1 0 Ribosomal protein S7e DUF1896 PF08989.5 EGG43008.1 - 0.089 12.6 0.5 0.13 12.1 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1896) Spore_GerAC PF05504.6 EGG43008.1 - 0.44 10.3 4.3 0.2 11.4 0.9 1.7 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal ALAD PF00490.16 EGG43009.1 - 8.4e-138 458.6 0.6 9.4e-138 458.5 0.4 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF2070 PF09843.4 EGG43009.1 - 5.2e-05 22.7 0.1 0.0001 21.8 0.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) GlutR_N PF05201.10 EGG43010.1 - 2e-41 141.0 1.0 3.4e-41 140.3 0.1 1.9 2 1 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 EGG43010.1 - 3.6e-23 82.1 0.3 8.1e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.15 EGG43010.1 - 7.9e-20 70.6 2.4 1.7e-19 69.5 1.7 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.12 EGG43010.1 - 0.00026 21.3 0.0 0.00074 19.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EGG43010.1 - 0.00039 19.6 0.0 0.0021 17.2 0.0 1.9 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGG43010.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Malic_M PF03949.10 EGG43010.1 - 0.0047 16.5 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Saccharop_dh PF03435.13 EGG43010.1 - 0.035 13.0 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 EGG43010.1 - 0.043 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Mt_ATP-synt_D PF05873.7 EGG43010.1 - 0.049 13.2 1.4 0.1 12.2 1.0 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) MutS_III PF05192.13 EGG43010.1 - 0.061 13.1 0.2 1 9.1 0.2 2.3 1 1 0 1 1 1 0 MutS domain III NAD_binding_2 PF03446.10 EGG43010.1 - 0.067 13.0 0.3 0.32 10.8 0.0 2.2 2 1 1 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase MAF_flag10 PF01973.13 EGG43010.1 - 0.068 12.6 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF115 LVIVD PF08309.6 EGG43010.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 LVIVD repeat DUF39 PF01837.11 EGG43011.1 - 0.0066 15.1 0.2 0.0075 14.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF39 Cas_Csa5 PF09702.5 EGG43011.1 - 0.023 14.7 1.8 0.026 14.6 1.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) CysG_dimeriser PF10414.4 EGG43011.1 - 0.051 13.0 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region BACK PF07707.10 EGG43011.1 - 0.099 12.4 1.0 2 8.3 0.2 2.0 1 1 1 2 2 2 0 BTB And C-terminal Kelch DUF3964 PF13107.1 EGG43011.1 - 0.11 12.7 0.8 0.13 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Baculo_p26 PF04766.7 EGG43011.1 - 0.17 11.0 0.7 0.18 11.0 0.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein RGS PF00615.14 EGG43011.1 - 0.55 10.3 3.0 0.63 10.1 2.1 1.2 1 1 0 1 1 1 0 Regulator of G protein signaling domain DnaI_N PF07319.6 EGG43011.1 - 1.6 9.0 5.6 5.3 7.3 1.4 2.0 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus HTH_AsnC-type PF13404.1 EGG43012.1 - 0.00098 18.6 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.16 EGG43012.1 - 0.011 15.3 0.0 8.4 6.1 0.0 3.8 3 1 0 3 3 3 0 AsnC family DUF2316 PF10078.4 EGG43012.1 - 0.12 12.3 0.0 26 4.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) zf-B_box PF00643.19 EGG43013.1 - 0.2 11.5 2.0 0.34 10.8 1.4 1.4 1 0 0 1 1 1 0 B-box zinc finger Aldo_ket_red PF00248.16 EGG43014.1 - 9.6e-55 185.3 0.1 1.1e-54 185.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Chlor_dismutase PF06778.7 EGG43015.1 - 1.1e-48 165.5 0.3 1.3e-48 165.2 0.2 1.1 1 0 0 1 1 1 1 Chlorite dismutase DUF1684 PF07920.6 EGG43015.1 - 0.085 12.6 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) NHL PF01436.16 EGG43016.1 - 8.3e-59 192.7 15.1 8.6e-10 38.0 0.0 6.5 6 0 0 6 6 6 6 NHL repeat SGL PF08450.7 EGG43016.1 - 4.6e-17 62.2 11.5 4.1e-08 32.9 1.5 4.5 1 1 3 4 4 4 4 SMP-30/Gluconolaconase/LRE-like region HemolysinCabind PF00353.14 EGG43016.1 - 3.1e-16 58.1 97.6 0.0013 18.8 1.6 10.9 5 1 5 14 14 13 10 Hemolysin-type calcium-binding repeat (2 copies) SBBP PF06739.6 EGG43016.1 - 7.8e-16 57.5 25.5 0.021 14.6 0.1 7.6 6 0 0 6 6 6 6 Beta-propeller repeat Arylesterase PF01731.15 EGG43016.1 - 3.8e-08 33.2 2.4 0.11 12.5 0.0 5.4 4 2 2 6 6 6 2 Arylesterase SdiA-regulated PF06977.6 EGG43016.1 - 1.7e-05 23.9 1.8 2.2 7.1 0.0 4.9 3 2 2 5 5 5 2 SdiA-regulated ThiC-associated PF13667.1 EGG43016.1 - 0.00057 19.3 1.4 28 4.3 0.0 5.2 4 1 1 5 5 5 0 ThiC-associated domain Rep_fac_C PF08542.6 EGG43016.1 - 0.0027 17.6 0.0 6.2 6.8 0.0 3.3 3 0 0 3 3 3 1 Replication factor C C-terminal domain Ldl_recept_b PF00058.12 EGG43016.1 - 0.003 17.8 0.4 21 5.5 0.0 5.2 5 0 0 5 5 5 0 Low-density lipoprotein receptor repeat class B CUB_2 PF02408.15 EGG43016.1 - 0.018 14.5 0.2 8.4 5.9 0.0 3.9 2 2 2 4 4 4 0 CUB-like domain DUF1838 PF08894.6 EGG43016.1 - 0.034 13.3 0.0 13 4.9 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1838) DUF859 PF05895.7 EGG43016.1 - 7.2 4.7 9.8 8.5 4.4 0.2 4.0 1 1 0 4 4 4 0 Siphovirus protein of unknown function (DUF859) SMC_N PF02463.14 EGG43017.1 - 5.9e-05 22.3 0.1 7.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGG43017.1 - 0.00051 20.0 0.0 0.00064 19.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain FR47 PF08445.5 EGG43017.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein ABC_tran PF00005.22 EGG43018.1 - 8.7e-12 45.5 0.0 1e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EGG43018.1 - 0.00014 21.7 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGG43018.1 - 0.0002 20.8 0.1 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGG43018.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EGG43018.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGG43018.1 - 0.0049 16.1 0.0 0.0064 15.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGG43018.1 - 0.0053 17.1 0.2 0.0086 16.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGG43018.1 - 0.0077 16.1 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG43018.1 - 0.01 15.8 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EGG43018.1 - 0.013 16.3 0.1 0.016 16.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGG43018.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ArgK PF03308.11 EGG43018.1 - 0.024 13.3 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_13 PF13166.1 EGG43018.1 - 0.039 12.4 0.0 0.045 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG43018.1 - 0.047 13.8 0.0 0.06 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGG43018.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EGG43018.1 - 0.076 12.9 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.10 EGG43018.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein T2SE PF00437.15 EGG43018.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EGG43018.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TFIIB PF00382.14 EGG43019.1 - 5.1e-25 87.0 2.4 8.1e-13 47.9 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG43019.1 - 5.5e-09 35.2 1.2 5.5e-09 35.2 0.9 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Cys_knot PF00007.17 EGG43019.1 - 0.04 13.9 1.1 0.12 12.4 0.7 1.8 1 0 0 1 1 1 0 Cystine-knot domain zf-ribbon_3 PF13248.1 EGG43019.1 - 0.067 12.4 0.3 0.067 12.4 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.1 EGG43019.1 - 0.068 12.6 2.1 0.97 8.9 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain DZR PF12773.2 EGG43019.1 - 0.079 12.7 2.7 0.18 11.6 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon RPA_interact_C PF14768.1 EGG43019.1 - 0.11 12.9 2.6 3.9 7.9 0.1 2.7 2 2 0 2 2 2 0 Replication protein A interacting C-terminal DUF2318 PF10080.4 EGG43019.1 - 0.13 12.0 3.7 7.2 6.4 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) RRN7 PF11781.3 EGG43019.1 - 0.15 11.5 1.5 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc-ribbons_6 PF07191.7 EGG43019.1 - 0.2 11.4 3.4 0.46 10.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons Gar1 PF04410.9 EGG43020.1 - 1.9e-06 27.4 0.0 2.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF782 PF05614.6 EGG43020.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) SRP19 PF01922.12 EGG43021.1 - 5e-17 62.2 0.1 5.8e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 SRP19 protein SRP54_N PF02881.14 EGG43021.1 - 0.11 12.5 1.3 2.7 8.1 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Ribosomal_S8e PF01201.17 EGG43022.1 - 1.7e-25 89.6 5.8 1.8e-25 89.5 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF690 PF05108.8 EGG43022.1 - 0.058 11.7 0.1 0.07 11.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF690) DUF387 PF04079.11 EGG43023.1 - 6e-36 123.2 0.7 7.2e-36 122.9 0.5 1.1 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) HHH_3 PF12836.2 EGG43023.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif HTH_20 PF12840.2 EGG43023.1 - 0.048 13.4 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PadR PF03551.9 EGG43023.1 - 0.055 13.2 0.5 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family TrmB PF01978.14 EGG43023.1 - 0.067 12.9 0.4 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB ScpA_ScpB PF02616.9 EGG43024.1 - 6.4e-14 52.1 3.2 3.1e-07 30.2 0.4 2.1 1 1 1 2 2 2 2 ScpA/B protein ADH_N PF08240.7 EGG43025.1 - 9.6e-35 118.6 0.9 1.5e-34 118.0 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG43025.1 - 3.1e-31 107.6 0.1 4.6e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGG43025.1 - 2.2e-11 44.7 0.0 3.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EGG43025.1 - 0.016 15.1 0.4 0.03 14.2 0.3 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EGG43025.1 - 0.024 14.6 0.3 0.061 13.3 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_18 PF12847.2 EGG43025.1 - 0.077 13.5 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Response_reg PF00072.19 EGG43026.1 - 2.7e-16 59.5 0.3 3.9e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain TPR_2 PF07719.12 EGG43026.1 - 0.0034 17.1 0.1 0.16 11.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG43026.1 - 0.0068 16.1 0.1 0.0068 16.1 0.1 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG43026.1 - 0.0089 15.9 0.4 0.47 10.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG43026.1 - 0.023 14.2 0.0 0.074 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EGG43026.1 - 0.031 14.4 7.2 0.095 12.8 0.4 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3910 PF13049.1 EGG43026.1 - 0.15 12.2 1.5 0.44 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) SMC_N PF02463.14 EGG43026.1 - 0.23 10.6 1.3 0.4 9.8 0.4 2.0 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain SCO1-SenC PF02630.9 EGG43026.1 - 0.31 10.6 4.8 4.2 6.9 0.2 2.3 2 1 0 2 2 2 0 SCO1/SenC fn3 PF00041.16 EGG43027.1 - 3.7e-05 23.7 0.4 9.2e-05 22.5 0.1 1.7 2 0 0 2 2 2 1 Fibronectin type III domain DUF1411 PF07199.6 EGG43027.1 - 0.053 12.9 0.2 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1411) HTH_24 PF13412.1 EGG43029.1 - 4.9e-10 38.6 1.4 1.1e-09 37.5 1.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EGG43029.1 - 2.8e-09 36.3 1.8 2.2e-08 33.5 0.8 2.5 2 1 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_12 PF08461.5 EGG43029.1 - 1.3e-07 31.2 1.7 1.3e-07 31.2 0.3 1.7 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_11 PF08279.7 EGG43029.1 - 8.4e-07 28.5 0.6 3.5e-06 26.5 0.4 2.1 1 1 0 1 1 1 1 HTH domain Penicillinase_R PF03965.11 EGG43029.1 - 5.1e-05 23.3 0.3 0.00032 20.7 0.0 2.0 2 0 0 2 2 2 1 Penicillinase repressor HTH_Tnp_Tc3_2 PF01498.13 EGG43029.1 - 9.4e-05 22.3 1.1 0.00025 21.0 0.1 2.1 3 0 0 3 3 3 1 Transposase HTH_20 PF12840.2 EGG43029.1 - 0.00012 21.8 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.7 EGG43029.1 - 0.0025 17.3 0.1 0.0091 15.5 0.1 2.0 1 1 0 1 1 1 1 DeoR-like helix-turn-helix domain Myb_DNA-bind_4 PF13837.1 EGG43029.1 - 0.0099 15.9 0.2 0.022 14.8 0.0 1.6 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain Arg_repressor PF01316.16 EGG43029.1 - 0.011 15.2 0.2 0.03 13.8 0.2 1.7 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_32 PF13565.1 EGG43029.1 - 0.013 16.2 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain RPA_C PF08784.6 EGG43029.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal FUR PF01475.14 EGG43029.1 - 0.02 14.7 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family RNA_binding PF01877.12 EGG43029.1 - 0.034 14.1 1.2 0.067 13.2 0.2 1.8 2 0 0 2 2 2 0 RNA binding DUF3783 PF12646.2 EGG43029.1 - 0.059 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) HxlR PF01638.12 EGG43029.1 - 0.063 12.9 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 HxlR-like helix-turn-helix Sigma70_r4_2 PF08281.7 EGG43029.1 - 0.066 12.6 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2203 PF09969.4 EGG43029.1 - 0.15 12.3 0.5 0.4 10.9 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HU-DNA_bdg PF14848.1 EGG43029.1 - 0.15 11.7 3.1 0.49 10.1 0.1 2.2 2 0 0 2 2 2 0 DNA-binding domain CxxCxxCC PF03692.10 EGG43030.1 - 3.2e-10 40.3 0.2 7.1e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain eIF-1a PF01176.14 EGG43031.1 - 4.4e-22 77.2 1.9 5.9e-22 76.8 1.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.14 EGG43031.1 - 0.16 11.6 1.3 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain CSD PF00313.17 EGG43032.1 - 1.7e-21 75.7 3.8 2.1e-21 75.4 2.7 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EGG43032.1 - 1e-06 28.1 0.9 1.1e-06 28.0 0.6 1.1 1 0 0 1 1 1 1 Ribonuclease B OB domain eIF-5a PF01287.15 EGG43034.1 - 2e-13 50.0 1.2 2.8e-13 49.6 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 EGG43034.1 - 9.7e-05 22.1 0.1 0.0035 17.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 EGG43034.1 - 0.077 12.7 0.4 0.54 10.0 0.1 2.3 2 0 0 2 2 2 0 KOW motif CBS PF00571.23 EGG43035.1 - 2.4e-08 33.6 0.6 0.01 15.5 0.0 3.8 5 0 0 5 5 5 2 CBS domain DHFR_1 PF00186.14 EGG43035.1 - 0.044 13.3 0.2 0.55 9.7 0.0 2.3 1 1 1 2 2 2 0 Dihydrofolate reductase CorA PF01544.13 EGG43036.1 - 1.3e-72 244.2 6.6 1.3e-72 244.2 4.6 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Herpes_UL92 PF03048.9 EGG43036.1 - 0.0041 16.7 0.1 0.014 15.0 0.1 2.0 1 0 0 1 1 1 1 UL92 family T2SF PF00482.18 EGG43036.1 - 0.013 15.4 0.0 0.013 15.4 0.0 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F PX PF00787.19 EGG43037.1 - 0.049 13.4 0.0 0.049 13.4 0.0 1.3 1 1 0 1 1 1 0 PX domain FAM75 PF14650.1 EGG43038.1 - 0.0049 16.3 2.8 0.0051 16.2 1.9 1.0 1 0 0 1 1 1 1 FAM75 family FCH PF00611.18 EGG43038.1 - 0.049 13.8 5.0 0.066 13.4 3.5 1.4 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1640 PF07798.6 EGG43038.1 - 0.053 13.5 4.0 0.054 13.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4473 PF14747.1 EGG43038.1 - 0.053 13.7 4.0 0.06 13.5 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Sedlin_N PF04628.8 EGG43039.1 - 0.94 9.3 4.5 1.9 8.3 0.3 3.0 1 1 2 3 3 3 0 Sedlin, N-terminal conserved region Aminotran_1_2 PF00155.16 EGG43040.1 - 1.2e-40 139.6 0.0 1.5e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG43040.1 - 0.05 12.7 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Phlebovirus_NSM PF07246.6 EGG43041.1 - 0.046 12.8 1.2 0.062 12.4 0.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4330 PF14221.1 EGG43041.1 - 0.066 13.0 2.3 4.4 7.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) BAAT_C PF08840.6 EGG43041.1 - 0.12 12.1 0.2 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Methyltransf_21 PF05050.7 EGG43042.1 - 2.1e-20 73.3 0.1 3.4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EGG43042.1 - 2e-07 31.5 0.0 3.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG43042.1 - 8.6e-07 28.6 0.0 2.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG43042.1 - 0.00041 20.1 0.0 0.0033 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EGG43042.1 - 0.0025 17.4 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 EGG43042.1 - 0.0026 17.7 0.0 0.0078 16.2 0.0 1.6 1 1 1 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 EGG43042.1 - 0.0055 16.2 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HEAT_2 PF13646.1 EGG43044.1 - 1.3e-12 47.8 0.1 3.3e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 EGG43044.1 - 0.01 15.8 0.0 3.8 7.8 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat COQ9 PF08511.6 EGG43044.1 - 0.044 13.3 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 COQ9 Cnd1 PF12717.2 EGG43044.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TrmB PF01978.14 EGG43045.1 - 0.0056 16.3 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Mga PF05043.8 EGG43045.1 - 0.064 13.5 1.3 1.1 9.5 0.0 2.8 2 1 0 2 2 2 0 Mga helix-turn-helix domain DUF1456 PF07308.8 EGG43045.1 - 0.11 12.6 2.3 0.27 11.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Response_reg PF00072.19 EGG43046.1 - 7.7e-23 80.6 0.4 8.6e-23 80.4 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain 2-Hacid_dh_C PF02826.14 EGG43046.1 - 0.019 14.1 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Alba PF01918.16 EGG43046.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Alba EamA PF00892.15 EGG43047.1 - 6.9e-33 113.3 28.9 1.8e-18 66.7 3.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EGG43047.1 - 6.8e-09 35.9 29.7 0.00015 21.9 10.5 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 EGG43047.1 - 0.043 13.6 0.5 0.043 13.6 0.4 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EGG43047.1 - 0.34 10.5 26.6 0.36 10.4 3.3 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF606 PF04657.8 EGG43047.1 - 0.94 9.5 21.1 0.069 13.2 8.2 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF606 Multi_Drug_Res PF00893.14 EGG43047.1 - 1.7 9.1 16.1 4.6 7.7 4.1 3.5 4 0 0 4 4 4 0 Small Multidrug Resistance protein Thioredoxin_4 PF13462.1 EGG43048.1 - 1.4e-35 122.6 0.0 1.9e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EGG43048.1 - 3.5e-12 46.2 0.0 6.7e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EGG43048.1 - 2.2e-08 34.3 0.0 7.1e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG43048.1 - 0.0016 18.4 0.3 0.13 12.3 0.2 2.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_5 PF13743.1 EGG43048.1 - 0.026 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Peptidase_S24 PF00717.18 EGG43051.1 - 1.4e-07 30.9 0.5 1.9e-07 30.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase S24-like 7TMR-DISM_7TM PF07695.6 EGG43052.1 - 0.0059 16.3 2.0 0.0065 16.1 1.4 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF606 PF04657.8 EGG43052.1 - 0.014 15.4 0.1 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF606 PKD_channel PF08016.7 EGG43052.1 - 0.023 13.1 0.2 0.024 13.0 0.2 1.0 1 0 0 1 1 1 0 Polycystin cation channel DUF1129 PF06570.6 EGG43052.1 - 0.046 13.0 0.2 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF373 PF04123.8 EGG43052.1 - 0.054 12.5 0.7 0.09 11.7 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) 7TM-7TMR_HD PF07698.6 EGG43052.1 - 0.076 12.4 3.7 0.098 12.0 2.6 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF3317 PF11779.3 EGG43052.1 - 0.47 9.9 2.8 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DUF721 PF05258.7 EGG43053.1 - 0.018 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF721) Sar8_2 PF03058.9 EGG43053.1 - 0.058 13.7 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Sar8.2 family DUF4352 PF11611.3 EGG43054.1 - 0.0055 16.8 0.3 0.0077 16.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) DUF3055 PF11256.3 EGG43055.1 - 0.064 13.3 0.0 0.094 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3055) Baculo_PEP_C PF04513.7 EGG43056.1 - 0.057 13.2 6.8 0.05 13.4 3.0 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4239 PF14023.1 EGG43056.1 - 0.18 11.1 1.5 0.21 10.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF2344 PF10105.4 EGG43056.1 - 1.9 7.9 8.8 2.3 7.6 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DZF PF07528.9 EGG43056.1 - 4.3 6.6 7.7 7.5 5.8 4.3 1.8 1 1 1 2 2 2 0 DZF domain RRF_GI PF12614.3 EGG43056.1 - 9 6.1 13.0 2.6 7.8 4.5 2.0 1 1 1 2 2 2 0 Ribosome recycling factor DUF3108 PF11306.3 EGG43058.1 - 0.025 14.2 0.2 0.054 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) TPR_11 PF13414.1 EGG43059.1 - 3.6e-22 77.7 1.5 5.6e-11 41.9 0.0 2.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGG43059.1 - 1e-16 59.7 1.0 3.3e-07 29.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG43059.1 - 5.4e-15 54.0 0.4 7.2e-07 28.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG43059.1 - 6.2e-14 52.0 0.1 4.8e-08 33.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG43059.1 - 5.5e-12 45.4 0.1 3e-06 27.0 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG43059.1 - 7.1e-12 44.5 0.3 0.0017 18.3 0.0 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGG43059.1 - 5.1e-11 41.5 2.5 1.6e-05 24.3 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG43059.1 - 2.5e-09 37.1 0.2 3.6e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGG43059.1 - 4.5e-09 36.1 0.0 0.02 15.5 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG43059.1 - 7.4e-09 34.7 0.0 0.0042 16.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGG43059.1 - 1.4e-08 35.1 0.0 0.00072 20.1 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG43059.1 - 6.7e-06 26.2 0.1 0.047 14.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGG43059.1 - 5.4e-05 22.9 1.1 0.048 13.5 0.1 3.2 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 EGG43059.1 - 0.00018 20.4 0.1 0.00021 20.2 0.0 1.0 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 EGG43059.1 - 0.00025 20.2 0.0 0.00036 19.6 0.0 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.3 EGG43059.1 - 0.0021 16.9 0.2 0.25 10.0 0.0 1.9 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 EGG43059.1 - 0.0055 16.5 0.0 0.1 12.4 0.0 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.11 EGG43060.1 - 0.0021 17.8 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Tmemb_cc2 PF10267.4 EGG43061.1 - 0.082 11.4 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF385 PF04075.9 EGG43062.1 - 7e-07 29.2 0.0 8.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF385) DUF2255 PF10012.4 EGG43062.1 - 0.028 14.3 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) PRC PF05239.11 EGG43063.1 - 5.3e-12 45.4 1.9 5.2e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain MCE PF02470.15 EGG43063.1 - 0.056 13.4 0.2 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 mce related protein DUF3945 PF13101.1 EGG43063.1 - 0.1 11.8 0.1 0.81 9.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3945) ABC_tran PF00005.22 EGG43064.1 - 1.1e-30 106.7 0.3 2.3e-30 105.6 0.0 1.7 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGG43064.1 - 3.5e-12 46.9 7.8 2.6e-09 37.4 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.1 EGG43064.1 - 2e-05 23.8 0.3 2e-05 23.8 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.1 EGG43064.1 - 2.3e-05 24.8 1.8 5.4e-05 23.6 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_29 PF13555.1 EGG43064.1 - 0.00066 19.1 0.3 0.0013 18.2 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EGG43064.1 - 0.0064 16.8 10.4 0.081 13.2 7.2 2.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGG43064.1 - 0.016 14.4 2.1 0.11 11.7 0.3 2.5 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGG43064.1 - 0.019 14.1 0.1 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 EGG43064.1 - 0.07 12.5 0.3 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.19 EGG43065.1 - 4.5e-34 117.4 18.6 4.5e-34 117.4 12.9 1.8 1 1 1 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EGG43065.1 - 5.4e-17 61.8 31.0 6.8e-17 61.5 21.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 EGG43065.1 - 3.4e-10 39.5 24.5 4.6e-10 39.0 17.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 EGG43065.1 - 4e-07 29.1 21.6 7.7e-07 28.2 14.9 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein MIP PF00230.15 EGG43066.1 - 1.2e-37 129.5 21.4 1.5e-37 129.2 14.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Papilloma_E5 PF03025.9 EGG43066.1 - 8 6.4 8.5 1.1 9.2 1.8 2.5 2 0 0 2 2 2 0 Papillomavirus E5 Aminotran_3 PF00202.16 EGG43067.1 - 1.4e-70 237.8 0.1 1.8e-70 237.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGG43067.1 - 3.7e-06 26.1 0.0 5.5e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II RasGAP_C PF03836.10 EGG43067.1 - 0.012 15.2 0.2 0.029 14.0 0.1 1.6 1 0 0 1 1 1 0 RasGAP C-terminus z-alpha PF02295.12 EGG43067.1 - 0.096 12.4 0.1 0.32 10.7 0.1 1.9 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain HAUS-augmin3 PF14932.1 EGG43067.1 - 0.14 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Porphobil_deam PF01379.15 EGG43068.1 - 3.1e-68 228.9 0.6 4.1e-68 228.5 0.4 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGG43068.1 - 2.9e-12 46.4 0.0 6.9e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TP_methylase PF00590.15 EGG43069.1 - 3.6e-49 167.3 0.0 4.1e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HEM4 PF02602.10 EGG43070.1 - 2.4e-42 144.7 0.0 2.7e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PGM_PMM_II PF02879.11 EGG43070.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PKD PF00801.15 EGG43071.1 - 3.7e-05 23.3 37.3 0.28 10.9 0.5 9.1 7 3 0 7 7 7 4 PKD domain FokI_N PF02981.10 EGG43071.1 - 0.0048 16.5 0.0 0.88 9.1 0.0 3.3 3 0 0 3 3 3 1 Restriction endonuclease FokI, recognition domain MFS_1 PF07690.11 EGG43073.1 - 1.1e-28 100.0 46.4 4.7e-20 71.6 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGG43073.1 - 0.00039 18.6 15.4 0.0011 17.1 4.1 2.3 2 1 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.2 EGG43073.1 - 0.0014 18.4 1.0 0.0014 18.4 0.7 3.4 3 1 0 3 3 3 1 MFS_1 like family BIV_Env PF05858.7 EGG43073.1 - 0.067 11.1 1.1 2.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) Sugar_tr PF00083.19 EGG43073.1 - 0.1 11.1 30.5 0.041 12.4 9.2 3.0 1 1 0 3 3 3 0 Sugar (and other) transporter DUF2976 PF11190.3 EGG43074.1 - 0.026 14.0 0.7 0.038 13.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) TatC PF00902.13 EGG43074.1 - 0.098 12.0 4.5 0.11 11.8 3.1 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF1426 PF07234.6 EGG43074.1 - 1.1 8.9 4.6 0.32 10.7 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1426) DUF872 PF05915.7 EGG43074.1 - 2.7 7.8 5.6 5.2 6.9 0.3 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TMEM238 PF15125.1 EGG43074.1 - 6.6 6.7 8.2 3.9 7.4 0.3 2.1 2 0 0 2 2 2 0 TMEM238 protein family DUF1059 PF06348.6 EGG43075.1 - 1.3e-20 72.9 1.2 1.4e-20 72.8 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Asn_synthase PF00733.16 EGG43075.1 - 0.1 12.0 0.1 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Asparagine synthase Frigida PF07899.6 EGG43075.1 - 0.11 11.2 0.7 0.11 11.2 0.5 1.0 1 0 0 1 1 1 0 Frigida-like protein CitMHS PF03600.11 EGG43076.1 - 0.063 11.8 0.3 0.071 11.6 0.2 1.1 1 0 0 1 1 1 0 Citrate transporter E1-E2_ATPase PF00122.15 EGG43076.1 - 0.07 12.1 0.8 0.08 11.9 0.6 1.0 1 0 0 1 1 1 0 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGG43076.1 - 0.12 11.8 4.1 0.15 11.6 2.9 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2592 PF10766.4 EGG43076.1 - 0.19 11.1 1.0 0.35 10.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Ribosomal_L36 PF00444.13 EGG43076.1 - 0.56 10.2 4.3 1 9.3 3.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L36 DUF3671 PF12420.3 EGG43076.1 - 1.1 9.2 4.0 1.9 8.5 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function UPF0051 PF01458.12 EGG43077.1 - 1.7e-69 233.8 0.2 2.2e-69 233.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.12 EGG43078.1 - 1.3e-67 227.6 1.1 1.8e-67 227.1 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF2152 PF10222.4 EGG43078.1 - 0.027 12.7 0.0 0.049 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) THF_DHG_CYH_C PF02882.14 EGG43078.1 - 0.042 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Rieske PF00355.21 EGG43079.1 - 1.6e-18 66.0 0.0 1.7e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EGG43079.1 - 2e-13 49.9 0.0 2.3e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Aminotran_5 PF00266.14 EGG43080.1 - 1.3e-151 504.5 0.4 1.5e-151 504.3 0.3 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGG43080.1 - 4.1e-07 29.2 0.2 3.7e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG43080.1 - 7.6e-06 25.2 0.0 1.9e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGG43080.1 - 0.00038 18.8 0.0 0.00083 17.7 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF4582 PF15189.1 EGG43080.1 - 0.11 11.6 0.9 1.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) NifU_N PF01592.11 EGG43081.1 - 3.4e-29 101.3 0.0 3.9e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Ste50p-SAM PF09235.5 EGG43081.1 - 0.12 12.4 1.3 0.91 9.6 0.1 2.3 2 0 0 2 2 2 0 Ste50p, sterile alpha motif DUF836 PF05768.9 EGG43081.1 - 0.14 12.3 0.9 0.21 11.8 0.3 1.7 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) PGK PF00162.14 EGG43083.1 - 3.1e-102 341.9 0.0 3.6e-102 341.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF218 PF02698.12 EGG43083.1 - 0.012 15.1 0.1 0.56 9.7 0.0 2.4 2 0 0 2 2 2 0 DUF218 domain CbiA PF01656.18 EGG43083.1 - 0.03 13.7 0.1 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PAP2 PF01569.16 EGG43084.1 - 3.9e-22 78.2 1.3 5.3e-22 77.8 0.6 1.4 1 1 1 2 2 2 2 PAP2 superfamily PAP2_3 PF14378.1 EGG43084.1 - 1.8e-06 27.6 1.2 3.2e-06 26.8 0.8 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EGG43084.1 - 1.7e-05 25.0 1.5 3.3e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal DUF1146 PF06612.6 EGG43084.1 - 0.28 11.1 5.0 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) TFIIB PF00382.14 EGG43086.1 - 1.6e-33 114.3 5.4 5.7e-18 64.5 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG43086.1 - 1.4e-08 33.9 0.1 2.2e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_11 PF08279.7 EGG43086.1 - 0.00011 21.7 2.1 0.066 12.8 0.0 3.3 3 0 0 3 3 3 1 HTH domain Cyclin_C PF02984.14 EGG43086.1 - 0.00029 20.7 0.1 1.5 8.8 0.0 2.7 3 0 0 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 EGG43086.1 - 0.0021 17.5 0.2 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_23 PF13384.1 EGG43086.1 - 0.0032 17.0 0.6 0.61 9.8 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_AsnC-type PF13404.1 EGG43086.1 - 0.0053 16.2 0.1 0.28 10.7 0.0 2.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EGG43086.1 - 0.0072 15.6 0.1 1.6 8.2 0.0 2.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.7 EGG43086.1 - 0.0073 15.7 2.6 0.74 9.3 0.0 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 EGG43086.1 - 0.0091 15.2 0.0 0.32 10.3 0.0 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 MarR PF01047.17 EGG43086.1 - 0.022 14.4 0.0 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 MarR family Peptidase_M13_N PF05649.8 EGG43086.1 - 0.035 13.1 1.8 0.75 8.7 0.2 2.3 2 1 0 2 2 2 0 Peptidase family M13 DUF294_C PF10335.4 EGG43086.1 - 0.036 13.7 0.1 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Phage_terminase PF10668.4 EGG43086.1 - 0.068 12.9 0.1 11 5.9 0.0 3.2 3 0 0 3 3 3 0 Phage terminase small subunit HTH_38 PF13936.1 EGG43086.1 - 0.17 11.4 1.9 3.8 7.1 0.0 3.2 4 0 0 4 4 4 0 Helix-turn-helix domain