# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PA_decarbox PF05870.11 EGG41049.1 - 0.038 13.6 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) SNO PF01174.19 EGG41050.1 - 5.3e-50 169.9 0.1 6.1e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGG41050.1 - 1.7e-12 47.3 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EGG41050.1 - 3.4e-11 43.3 0.0 6e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG41050.1 - 1.1e-06 28.6 0.1 3.7e-05 23.6 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EGG41050.1 - 1.8e-06 27.9 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 EGG41050.1 - 3e-06 27.1 0.1 4.2e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S51 SOR_SNZ PF01680.17 EGG41051.1 - 1.6e-98 328.6 3.2 2.1e-98 328.2 3.2 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGG41051.1 - 3.8e-07 29.7 1.3 1.5e-05 24.4 0.1 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGG41051.1 - 6.5e-05 22.5 0.3 0.015 14.8 0.0 3.1 2 1 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 EGG41051.1 - 0.0014 17.8 0.3 1.2 8.1 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 EGG41051.1 - 0.0015 18.0 4.6 0.16 11.3 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 EGG41051.1 - 0.0022 17.2 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase OMPdecase PF00215.24 EGG41051.1 - 0.013 15.1 0.5 1.2 8.7 0.1 2.5 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NanE PF04131.14 EGG41051.1 - 0.021 14.0 2.9 0.74 9.0 0.0 3.3 2 2 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Aconitase PF00330.20 EGG41053.1 - 3.9e-146 487.7 0.0 7.2e-146 486.8 0.0 1.4 2 0 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG41053.1 - 4.3e-35 120.9 0.1 1.6e-34 119.1 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF521 PF04412.13 EGG41053.1 - 0.021 13.5 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) F-box-like_2 PF13013.6 EGG41054.1 - 0.039 13.9 0.1 0.48 10.4 0.1 2.1 1 1 0 1 1 1 0 F-box-like domain COesterase PF00135.28 EGG41055.1 - 0.012 14.5 0.3 0.017 14.0 0.2 1.3 1 1 0 1 1 1 0 Carboxylesterase family AsnC_trans_reg PF01037.21 EGG41056.1 - 5.3e-11 42.3 0.0 6.1e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 EGG41056.1 - 0.0019 18.2 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 NapD protein EVE PF01878.18 EGG41057.1 - 1.9e-36 125.3 0.2 2.1e-36 125.1 0.2 1.0 1 0 0 1 1 1 1 EVE domain ATG11 PF10377.9 EGG41057.1 - 0.08 13.0 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 tRNA_synthFbeta PF17759.1 EGG41060.1 - 2e-38 132.0 0.0 6.8e-38 130.2 0.0 1.7 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 EGG41060.1 - 3.1e-18 65.8 0.0 1.6e-11 44.3 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.17 EGG41060.1 - 2.7e-12 46.7 0.3 4.8e-12 45.9 0.3 1.3 1 0 0 1 1 1 1 B3/4 domain DUF3215 PF11503.8 EGG41060.1 - 0.08 12.8 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) tRNA-synt_2d PF01409.20 EGG41061.1 - 1.4e-82 276.9 0.0 2.3e-82 276.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 EGG41061.1 - 4.2e-06 26.4 0.0 0.00049 19.6 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD3 PF18553.1 EGG41061.1 - 0.0067 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 EGG41061.1 - 0.0078 15.3 0.1 0.029 13.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EGG41061.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) HTH_9 PF08221.11 EGG41061.1 - 0.18 11.9 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain tRNA-synt_1b PF00579.25 EGG41062.1 - 1.6e-29 103.2 0.0 2.7e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 EGG41062.1 - 0.048 12.6 0.2 0.46 9.3 0.0 2.2 1 1 1 2 2 2 0 tRNA synthetases class I (K) zinc_ribbon_6 PF14599.6 EGG41065.1 - 0.023 14.7 20.2 0.32 11.0 2.7 4.0 4 2 0 4 4 4 0 Zinc-ribbon Apidaecin PF00807.17 EGG41065.1 - 0.069 13.3 1.7 14 5.9 0.1 2.7 2 0 0 2 2 2 0 Apidaecin Ribosomal_L37e PF01907.19 EGG41065.1 - 2.6 8.3 0.0 2.6 8.3 0.0 4.2 4 0 0 4 4 4 0 Ribosomal protein L37e DNA_RNApol_7kD PF03604.13 EGG41065.1 - 4 7.2 17.9 4.5 7.0 2.5 3.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit CTP_transf_like PF01467.26 EGG41067.1 - 1.7e-14 54.3 0.0 2.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EGG41067.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.7 2 0 0 2 2 2 0 FAD synthetase Pantoate_ligase PF02569.15 EGG41067.1 - 0.031 13.5 0.1 0.47 9.6 0.0 2.0 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase DpaA_N PF16924.5 EGG41067.1 - 0.081 13.0 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Wzt_C PF14524.6 EGG41068.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Wzt C-terminal domain OapA PF04225.12 EGG41068.1 - 0.057 13.5 0.1 0.17 12.0 0.1 1.9 1 1 0 1 1 1 0 Opacity-associated protein A LysM-like domain AhpC-TSA PF00578.21 EGG41071.1 - 7.9e-21 74.2 0.4 1e-20 73.9 0.4 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG41071.1 - 7.5e-13 48.4 0.1 9.5e-13 48.1 0.1 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGG41071.1 - 4.8e-07 30.0 0.6 8.4e-07 29.2 0.6 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGG41071.1 - 0.0052 17.2 0.2 0.0083 16.6 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain T4_deiodinase PF00837.17 EGG41071.1 - 0.0057 16.0 0.0 0.0084 15.4 0.0 1.3 1 1 0 1 1 1 1 Iodothyronine deiodinase Thioredoxin PF00085.20 EGG41071.1 - 0.036 14.1 0.4 0.81 9.7 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 EGG41071.1 - 0.058 13.4 0.4 0.46 10.6 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin domain TraF PF13728.6 EGG41071.1 - 0.072 12.9 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein B12-binding_2 PF02607.17 EGG41072.1 - 2.2e-05 24.8 0.0 4.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain HTH_IclR PF09339.10 EGG41072.1 - 3e-05 23.7 0.0 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_11 PF08279.12 EGG41072.1 - 0.00036 20.4 0.0 0.00084 19.2 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 EGG41072.1 - 0.00079 18.9 0.0 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EGG41072.1 - 0.001 18.8 0.0 0.0027 17.4 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EGG41072.1 - 0.0031 17.5 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix MarR PF01047.22 EGG41072.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 MarR family CtsR_C PF17727.1 EGG41072.1 - 0.048 13.8 0.0 0.2 11.8 0.0 2.1 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain MarR_2 PF12802.7 EGG41072.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 MarR family TEX12 PF15219.6 EGG41072.1 - 0.18 12.1 3.0 8.9 6.7 0.1 2.8 3 0 0 3 3 3 0 Testis-expressed 12 HTH_28 PF13518.6 EGG41072.1 - 0.19 11.9 0.0 0.68 10.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_Tnp_IS240 PF13610.6 EGG41073.1 - 1.5e-22 80.4 0.8 2.4e-22 79.7 0.8 1.3 1 0 0 1 1 1 1 DDE domain rve PF00665.26 EGG41073.1 - 8.3e-07 29.2 0.1 1.5e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EGG41073.1 - 7.9e-06 25.6 0.3 3.2e-05 23.6 0.1 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS66 PF03050.14 EGG41073.1 - 1.8e-05 24.4 0.1 2.1e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Transposase IS66 family Transposase_mut PF00872.18 EGG41073.1 - 0.013 14.4 1.0 0.52 9.1 0.1 2.1 2 0 0 2 2 2 0 Transposase, Mutator family PcfK PF14058.6 EGG41073.1 - 0.063 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 PcfK-like protein HTH_23 PF13384.6 EGG41073.1 - 0.14 12.0 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Rieske PF00355.26 EGG41074.1 - 0.043 13.8 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DDR_swiveling PF18427.1 EGG41075.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain MINDY_DUB PF04424.13 EGG41077.1 - 0.014 15.5 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 MINDY deubiquitinase CybS PF05328.12 EGG41077.1 - 0.032 13.9 0.1 0.038 13.7 0.1 1.1 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Phage_holin_2_3 PF16080.5 EGG41078.1 - 0.023 14.4 0.2 0.049 13.4 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 PMP1_2 PF08114.11 EGG41078.1 - 0.13 12.1 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 ATPase proteolipid family DDE_Tnp_IS240 PF13610.6 EGG41079.1 - 7.2e-22 78.1 0.8 1.4e-21 77.2 0.8 1.5 1 0 0 1 1 1 1 DDE domain rve PF00665.26 EGG41079.1 - 9.9e-07 29.0 0.0 2.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EGG41079.1 - 2.2e-05 24.1 0.1 7.4e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain SWIM PF04434.17 EGG41079.1 - 0.00024 20.7 0.1 0.00046 19.8 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS66 PF03050.14 EGG41079.1 - 0.00026 20.6 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family Zn_Tnp_IS1 PF03811.13 EGG41079.1 - 0.013 15.2 1.9 0.013 15.2 1.9 1.9 2 0 0 2 2 2 0 InsA N-terminal domain zf-LYAR PF08790.11 EGG41079.1 - 0.02 14.8 1.1 0.047 13.6 1.1 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger EPF PF17181.4 EGG41079.1 - 0.55 10.3 7.4 8.8 6.4 2.4 2.4 2 0 0 2 2 2 0 Epidermal patterning factor proteins zf-Dof PF02701.15 EGG41079.1 - 0.68 10.1 4.6 1.8 8.8 4.6 1.7 1 0 0 1 1 1 0 Dof domain, zinc finger zf-ISL3 PF14690.6 EGG41079.1 - 2.3 9.0 5.9 18 6.1 4.7 2.9 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RHH_1 PF01402.21 EGG41080.1 - 0.015 15.2 0.2 0.02 14.8 0.2 1.1 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family HD_2 PF12917.7 EGG41080.1 - 0.13 12.0 0.5 0.12 12.1 0.5 1.0 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme YicC_N PF03755.13 EGG41081.1 - 0.018 15.5 0.1 0.03 14.8 0.1 1.3 1 0 0 1 1 1 0 YicC-like family, N-terminal region Lectin_like PF18560.1 EGG41082.1 - 0.0042 17.3 0.3 0.0052 17.0 0.3 1.1 1 0 0 1 1 1 1 Lectin like domain LOH1CR12 PF10158.9 EGG41082.1 - 0.054 13.5 0.2 0.48 10.4 0.2 2.0 1 1 1 2 2 2 0 Tumour suppressor protein MethyltransfD12 PF02086.15 EGG41083.1 - 6.6e-64 216.1 1.0 7.5e-64 215.9 1.0 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF2089 PF09862.9 EGG41083.1 - 0.0035 17.3 0.1 0.0074 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) Cons_hypoth95 PF03602.15 EGG41083.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Archaeal_AmoA PF12942.7 EGG41084.1 - 1.1e-117 390.3 16.9 1.3e-117 390.1 16.9 1.1 1 0 0 1 1 1 1 Archaeal ammonia monooxygenase subunit A (AmoA) AmoC PF04896.12 EGG41086.1 - 2.4e-13 49.9 6.3 3e-13 49.6 6.3 1.1 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C RTA1 PF04479.13 EGG41086.1 - 0.0059 16.2 0.2 0.009 15.6 0.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Monooxygenase_B PF04744.12 EGG41087.1 - 3.5e-08 32.7 0.1 9e-08 31.4 0.1 1.6 1 1 0 1 1 1 1 Monooxygenase subunit B protein FixQ PF05545.11 EGG41090.1 - 0.11 12.5 1.4 0.17 11.9 1.4 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ COX7C PF02935.16 EGG41092.1 - 0.086 13.1 0.4 0.086 13.1 0.4 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Ribosomal_S13_N PF08069.12 EGG41094.1 - 1.3e-26 92.4 0.1 2.3e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGG41094.1 - 1e-11 44.9 0.3 1.6e-11 44.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Nnf1 PF03980.14 EGG41094.1 - 0.12 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Nnf1 DHHA1 PF02272.19 EGG41095.1 - 4.3e-11 43.4 0.5 1.4e-10 41.7 0.1 2.0 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.20 EGG41095.1 - 0.0047 17.1 0.1 0.0099 16.1 0.1 1.6 1 0 0 1 1 1 1 DHH family Pcc1 PF09341.10 EGG41096.1 - 0.00054 20.0 0.0 0.00069 19.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 tRNA-synt_2b PF00587.25 EGG41097.1 - 3.8e-37 128.0 0.1 6.8e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGG41097.1 - 2.5e-24 85.6 11.2 5.3e-24 84.5 11.2 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 EGG41097.1 - 0.45 9.7 5.2 0.24 10.6 3.3 1.5 2 0 0 2 2 2 0 TMPIT-like protein Ribosomal_S3Ae PF01015.18 EGG41098.1 - 2.4e-59 200.3 4.9 2.7e-59 200.1 4.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family RNA_binding PF01877.17 EGG41099.1 - 1.4e-26 93.1 4.4 1.7e-26 92.8 4.4 1.1 1 0 0 1 1 1 1 RNA binding DUF1722 PF08349.11 EGG41099.1 - 0.073 13.3 0.5 1.6 9.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) FAD_binding_2 PF00890.24 EGG41101.1 - 1.1e-06 28.0 1.7 0.026 13.6 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EGG41101.1 - 1e-05 25.1 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGG41101.1 - 0.00027 19.9 0.0 0.0077 15.1 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 EGG41101.1 - 0.00048 19.4 2.5 0.0073 15.6 2.0 2.6 1 1 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGG41101.1 - 0.0022 17.3 0.1 0.0052 16.1 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG41101.1 - 0.0025 17.1 0.5 0.087 12.1 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EGG41101.1 - 0.0037 16.4 0.1 0.0056 15.8 0.1 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EGG41101.1 - 0.0074 15.9 0.8 1.3 8.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG41101.1 - 0.034 14.4 0.1 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGG41101.1 - 0.082 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 EGG41101.1 - 0.097 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain AAA_5 PF07728.14 EGG41102.1 - 2.4e-23 82.7 0.1 3.3e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGG41102.1 - 2.9e-13 49.8 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGG41102.1 - 6.9e-08 33.0 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGG41102.1 - 4e-06 26.5 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EGG41102.1 - 4.3e-06 26.8 0.1 6.6e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGG41102.1 - 4.9e-06 26.4 0.0 8.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain ATPase_2 PF01637.18 EGG41102.1 - 4.5e-05 23.5 0.1 6.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGG41102.1 - 9.4e-05 22.9 0.1 0.00026 21.4 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_6 PF12774.7 EGG41102.1 - 0.00028 20.0 0.0 0.0016 17.4 0.0 1.9 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region MCM PF00493.23 EGG41102.1 - 0.00047 19.3 0.0 0.00076 18.6 0.0 1.3 1 1 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 EGG41102.1 - 0.001 18.8 0.4 0.05 13.3 0.2 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 EGG41102.1 - 0.0012 19.0 0.0 0.0049 17.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.6 EGG41102.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG41102.1 - 0.002 18.4 0.1 0.0035 17.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGG41102.1 - 0.0025 17.2 0.1 0.46 9.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGG41102.1 - 0.0026 18.3 0.1 0.0051 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 EGG41102.1 - 0.0057 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CbbQ_C PF08406.10 EGG41102.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal AAA_28 PF13521.6 EGG41102.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EGG41102.1 - 0.019 15.1 0.4 0.053 13.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TniB PF05621.11 EGG41102.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Rad17 PF03215.15 EGG41102.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 EGG41102.1 - 0.03 14.0 0.2 0.16 11.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGG41102.1 - 0.038 13.7 0.2 0.15 11.8 0.1 1.8 1 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGG41102.1 - 0.044 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EGG41102.1 - 0.054 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGG41102.1 - 0.06 13.9 0.1 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter RNA12 PF10443.9 EGG41102.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein cobW PF02492.19 EGG41102.1 - 0.07 12.7 0.1 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGG41102.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGG41102.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase VWA PF00092.28 EGG41103.1 - 3.3e-07 30.7 0.0 6.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG41103.1 - 0.014 16.0 0.0 0.039 14.6 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF3828 PF12883.7 EGG41103.1 - 0.067 13.6 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) Thioredoxin_10 PF17991.1 EGG41105.1 - 1.1e-36 126.5 0.0 1.6e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin like C-terminal domain AhpC-TSA PF00578.21 EGG41105.1 - 1.2e-08 35.0 0.1 1.9e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG41105.1 - 5.6e-08 32.6 0.0 9.7e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGG41105.1 - 0.0017 18.7 0.1 0.0033 17.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Gemini_AL1 PF00799.20 EGG41105.1 - 0.084 13.2 0.3 6 7.3 0.1 2.4 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain DsbD PF02683.15 EGG41106.1 - 6.6e-49 166.7 21.5 7.8e-49 166.4 21.5 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 EGG41106.1 - 3.9e-06 26.9 15.0 6e-06 26.3 15.0 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region SfLAP PF11139.8 EGG41106.1 - 0.00052 19.5 7.8 0.017 14.6 3.0 2.5 1 1 1 2 2 2 2 Sap, sulfolipid-1-addressing protein Baculo_11_kDa PF06143.11 EGG41106.1 - 0.55 9.8 0.0 0.55 9.8 0.0 2.7 4 0 0 4 4 4 0 Baculovirus 11 kDa family DUF373 PF04123.13 EGG41106.1 - 0.58 9.6 15.7 0.92 8.9 13.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) PALP PF00291.25 EGG41107.1 - 5.4e-21 75.3 0.0 3.5e-19 69.3 0.0 3.1 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ASCH PF04266.14 EGG41108.1 - 3.1e-10 40.6 0.0 3.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ASCH domain TBP PF00352.21 EGG41109.1 - 1.2e-54 182.2 0.0 9.2e-28 96.0 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGG41109.1 - 8e-06 25.9 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) NERD PF08378.11 EGG41111.1 - 0.023 15.2 2.7 0.24 11.9 0.3 2.2 1 1 1 2 2 2 0 Nuclease-related domain CHDNT PF08073.12 EGG41111.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 CHDNT (NUC034) domain PIRT PF15099.6 EGG41112.1 - 0.0048 16.5 1.0 0.0073 15.9 1.0 1.4 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family DUF3899 PF13038.6 EGG41112.1 - 0.007 16.8 1.1 0.021 15.3 0.5 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3899) I-set PF07679.16 EGG41112.1 - 0.014 15.5 0.2 0.027 14.5 0.2 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain Type2_restr_D3 PF16902.5 EGG41113.1 - 0.045 13.7 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain HTH_10 PF04967.12 EGG41113.1 - 0.069 13.0 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain P-II PF00543.22 EGG41114.1 - 6.4e-13 49.2 3.6 7.5e-13 49.0 3.6 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Saf_2TM PF18303.1 EGG41115.1 - 0.021 14.4 0.3 0.024 14.2 0.3 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Erv26 PF04148.13 EGG41115.1 - 0.079 12.8 0.3 0.084 12.7 0.3 1.3 1 1 0 1 1 1 0 Transmembrane adaptor Erv26 DUF5433 PF17498.2 EGG41115.1 - 0.11 12.7 1.1 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5433) AsnC_trans_reg PF01037.21 EGG41119.1 - 5.7e-20 71.1 0.3 8.2e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain NapD PF03927.13 EGG41119.1 - 9.9e-08 31.9 1.0 0.00068 19.6 0.1 3.0 2 1 0 2 2 2 2 NapD protein GYD PF08734.11 EGG41119.1 - 0.00066 19.6 0.0 0.7 9.9 0.0 2.3 2 0 0 2 2 2 2 GYD domain HMA PF00403.26 EGG41119.1 - 0.011 16.1 2.0 1.6 9.3 0.4 3.0 2 1 1 3 3 3 0 Heavy-metal-associated domain Tn916-Xis PF09035.10 EGG41119.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Ferritin PF00210.24 EGG41119.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain ACT_4 PF13291.6 EGG41119.1 - 0.057 14.0 1.0 53 4.5 0.0 3.8 3 1 1 4 4 4 0 ACT domain ORF6C PF10552.9 EGG41119.1 - 0.068 13.3 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 ORF6C domain PMT2_N PF17987.1 EGG41119.1 - 0.1 12.8 0.4 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoethanolamine N-methyltransferase 2 N-terminal DUF2129 PF09902.9 EGG41119.1 - 0.12 12.5 0.5 22 5.2 0.0 2.9 3 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2129) AsnC_trans_reg PF01037.21 EGG41120.1 - 2.1e-12 46.8 0.1 2.4e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 EGG41120.1 - 0.013 15.6 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 NapD protein Dus PF01207.17 EGG41121.1 - 2.8e-73 246.7 0.0 3.4e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EGG41121.1 - 3.8e-08 32.9 0.1 5e-06 25.9 0.1 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 EGG41121.1 - 6.5e-05 22.2 0.0 0.00016 20.9 0.0 1.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Oxidored_FMN PF00724.20 EGG41121.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MR_MLE_C PF13378.6 EGG41121.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like His_biosynth PF00977.21 EGG41121.1 - 0.0072 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein IMPDH PF00478.25 EGG41121.1 - 0.0077 15.3 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGG41121.1 - 0.035 13.1 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase TSP_3 PF02412.18 EGG41122.1 - 8.8e-43 143.7 190.3 0.0013 18.4 0.7 23.6 23 7 1 24 24 24 17 Thrombospondin type 3 repeat AKAP7_RIRII_bdg PF10470.9 EGG41122.1 - 1.4e-06 28.3 3.2 4.3 7.5 0.0 6.8 7 0 0 7 7 7 2 PKA-RI-RII subunit binding domain of A-kinase anchor protein DUF282 PF03380.14 EGG41122.1 - 0.0033 17.3 23.4 34 4.5 0.0 10.2 11 0 0 11 11 11 3 Caenorhabditis protein of unknown function, DUF282 ChitinaseA_N PF08329.10 EGG41122.1 - 0.24 11.0 4.7 4 7.1 0.2 3.0 3 0 0 3 3 3 0 Chitinase A, N-terminal domain TSP_3 PF02412.18 EGG41123.1 - 8.7e-48 159.7 221.6 5.9e-05 22.7 2.4 23.9 25 7 0 25 25 25 17 Thrombospondin type 3 repeat DUF282 PF03380.14 EGG41123.1 - 0.0013 18.6 35.6 37 4.3 0.1 13.0 14 0 0 14 14 14 3 Caenorhabditis protein of unknown function, DUF282 ChitinaseA_N PF08329.10 EGG41123.1 - 0.0083 15.8 3.0 1.9 8.2 0.3 3.0 2 0 0 2 2 2 2 Chitinase A, N-terminal domain Excalibur PF05901.11 EGG41123.1 - 8.3 7.1 0.0 8.3 7.1 0.0 17.2 18 1 0 18 18 18 0 Excalibur calcium-binding domain TSP_3 PF02412.18 EGG41124.1 - 5.3e-56 186.0 227.0 1.4e-05 24.6 1.5 26.3 22 11 4 26 26 26 19 Thrombospondin type 3 repeat DUF282 PF03380.14 EGG41124.1 - 3.7e-07 29.9 28.9 4.7 7.2 0.3 12.4 13 0 0 13 13 13 4 Caenorhabditis protein of unknown function, DUF282 CBP PF12192.8 EGG41124.1 - 0.0018 18.4 0.0 1.3e+02 2.9 0.0 6.7 9 0 0 9 9 9 0 Fungal calcium binding protein AKAP7_RIRII_bdg PF10470.9 EGG41124.1 - 0.0092 16.0 6.0 12 6.1 0.0 7.0 10 0 0 10 10 10 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein NOPS PF08075.11 EGG41124.1 - 3.9 7.7 19.7 1.7e+02 2.5 0.0 9.8 11 0 0 11 11 11 0 NOPS (NUC059) domain Radical_SAM PF04055.21 EGG41125.1 - 1.9e-20 73.9 0.0 6.7e-20 72.1 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 EGG41125.1 - 2.4e-20 72.6 0.1 1.8e-19 69.9 0.1 2.3 2 0 0 2 2 2 1 Wyosine base formation Fer4_14 PF13394.6 EGG41125.1 - 0.038 14.1 1.6 0.74 10.0 0.8 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain AAT PF03417.16 EGG41125.1 - 0.058 13.1 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SAS4 PF15460.6 EGG41125.1 - 0.069 13.3 0.7 0.18 11.9 0.3 1.8 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ham1p_like PF01725.16 EGG41126.1 - 2e-41 142.0 0.0 2.2e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RIO1 PF01163.22 EGG41127.1 - 4.2e-10 39.5 0.0 5.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGG41127.1 - 1.5e-08 34.3 0.2 7.5e-08 32.0 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGG41127.1 - 4.3e-07 29.6 0.5 5.5e-07 29.2 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGG41127.1 - 2.3e-05 24.4 0.0 0.1 12.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EGG41127.1 - 0.00076 18.8 0.4 0.0026 17.1 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase WaaY PF06176.11 EGG41127.1 - 0.0026 17.4 1.0 0.0041 16.8 1.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1679 PF07914.11 EGG41127.1 - 0.0098 14.8 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) PIF6 PF05341.11 EGG41127.1 - 0.12 12.5 0.1 2.1 8.5 0.0 2.4 2 1 1 3 3 3 0 Per os infectivity factor 6 EcKinase PF02958.20 EGG41127.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Cation_efflux PF01545.21 EGG41128.1 - 5.5e-33 114.4 12.2 6.7e-33 114.1 12.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGG41128.1 - 0.00024 21.2 2.6 0.00038 20.5 2.6 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Spore_YhcN_YlaJ PF09580.10 EGG41128.1 - 0.11 12.6 0.3 0.17 11.9 0.3 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ThrE PF06738.12 EGG41128.1 - 0.9 8.8 7.1 2 7.7 0.5 2.9 2 1 0 3 3 3 0 Putative threonine/serine exporter GP57 PF17594.2 EGG41129.1 - 0.042 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 7kD_DNA_binding PF02294.18 EGG41129.1 - 0.065 13.3 0.3 0.1 12.7 0.3 1.4 1 0 0 1 1 1 0 7kD DNA-binding domain PH_2 PF08458.10 EGG41129.1 - 0.083 13.3 0.2 0.13 12.6 0.2 1.3 1 1 0 1 1 1 0 Plant pleckstrin homology-like region Peptidase_M22 PF00814.25 EGG41130.1 - 1.4e-75 254.5 0.0 1.6e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family MMR_HSR1_C PF08438.10 EGG41131.1 - 8.6e-30 103.6 1.2 2.3e-29 102.3 0.3 2.0 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGG41131.1 - 1.4e-20 73.5 0.1 3.8e-19 68.8 0.0 2.8 2 1 0 3 3 3 1 50S ribosome-binding GTPase TGS PF02824.21 EGG41131.1 - 3.6e-12 46.1 0.2 8.7e-12 44.9 0.2 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGG41131.1 - 1.6e-06 27.7 0.2 6.2e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B YchF-GTPase_C PF06071.13 EGG41131.1 - 0.0028 17.8 0.2 0.011 15.9 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1_Xtn PF16897.5 EGG41131.1 - 0.08 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain CPSase_L_D3 PF02787.19 EGG41131.1 - 0.33 11.3 1.2 0.83 10.0 0.5 2.0 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain AAA_18 PF13238.6 EGG41132.1 - 5.5e-10 39.9 0.5 1.4e-09 38.6 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EGG41132.1 - 0.00075 19.9 0.0 0.0021 18.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGG41132.1 - 0.0043 17.0 0.8 0.015 15.2 0.1 2.1 2 1 0 2 2 2 1 NTPase Cytidylate_kin2 PF13189.6 EGG41132.1 - 0.011 15.9 0.0 0.28 11.3 0.0 2.1 1 1 1 2 2 2 0 Cytidylate kinase-like family KTI12 PF08433.10 EGG41132.1 - 0.017 14.6 0.1 0.044 13.2 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EGG41132.1 - 0.033 14.6 0.0 0.033 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Sulfotransfer_1 PF00685.27 EGG41132.1 - 0.038 13.5 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain Cytidylate_kin PF02224.18 EGG41132.1 - 0.04 13.7 0.1 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase CoaE PF01121.20 EGG41132.1 - 0.055 13.1 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_17 PF13207.6 EGG41132.1 - 0.057 13.8 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain GP11 PF08677.10 EGG41132.1 - 0.087 12.3 0.1 0.14 11.6 0.0 1.4 2 0 0 2 2 2 0 GP11 baseplate wedge protein AAA_5 PF07728.14 EGG41132.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EGG41132.1 - 0.097 12.6 0.7 0.48 10.3 0.1 2.2 2 1 0 2 2 2 0 RsgA GTPase TGT PF01702.18 EGG41133.1 - 2.3e-69 234.2 0.0 3.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 EGG41133.1 - 1.1e-10 41.6 0.2 2e-10 40.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) Fer4 PF00037.27 EGG41134.1 - 2e-11 43.2 10.3 7.8e-06 25.5 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGG41134.1 - 4.5e-09 36.7 3.2 6.5e-09 36.2 3.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGG41134.1 - 8.1e-09 35.2 7.3 7.8e-05 22.6 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EGG41134.1 - 1.2e-08 34.9 1.5 1.7e-08 34.4 1.5 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG41134.1 - 1.2e-06 28.2 8.3 0.0014 18.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 EGG41134.1 - 2.7e-06 27.8 4.5 0.0042 17.6 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 EGG41134.1 - 1.2e-05 25.3 8.0 0.00027 21.0 8.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG41134.1 - 1.5e-05 25.0 4.6 8.9e-05 22.6 4.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EGG41134.1 - 8.6e-05 22.7 7.5 0.022 15.2 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EGG41134.1 - 0.00016 22.5 3.4 0.28 12.1 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 EGG41134.1 - 0.00092 20.0 2.4 0.43 11.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 EGG41134.1 - 0.0019 18.9 10.5 0.0072 17.0 2.6 2.3 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_8 PF13183.6 EGG41134.1 - 0.0023 18.3 5.7 0.025 15.0 5.9 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGG41134.1 - 0.0032 18.3 10.4 0.098 13.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGG41134.1 - 0.028 15.0 7.5 1.2 9.7 7.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EGG41134.1 - 0.59 10.4 9.7 1.4 9.2 2.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain RMMBL PF07521.12 EGG41136.1 - 2.3e-16 59.5 0.2 5.3e-16 58.3 0.1 1.7 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 EGG41136.1 - 6.4e-14 52.2 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.7 EGG41136.1 - 4.7e-11 42.6 0.0 8.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG41136.1 - 1.6e-10 41.3 1.3 2.6e-09 37.4 1.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGG41136.1 - 3.8e-08 33.0 0.0 6.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGG41136.1 - 7.2e-06 26.0 0.0 3.7e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NB-ARC PF00931.22 EGG41136.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain HhH-GPD PF00730.25 EGG41137.1 - 3.1e-11 43.7 0.1 4.5e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 EGG41137.1 - 3.9e-11 43.1 0.2 0.00016 21.7 0.1 2.6 1 1 1 2 2 2 2 8-oxoguanine DNA glycosylase, N-terminal domain RNA_helicase PF00910.22 EGG41137.1 - 0.016 15.6 0.2 0.049 14.0 0.2 1.8 1 0 0 1 1 1 0 RNA helicase Copper-bind PF00127.20 EGG41139.1 - 6.1e-06 26.6 0.0 9.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EGG41139.1 - 0.032 14.3 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Cupredoxin-like domain Cytochrome_B PF00033.19 EGG41140.1 - 1.3e-29 103.4 9.9 1.3e-29 103.4 9.9 2.4 3 0 0 3 3 3 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 EGG41140.1 - 2e-25 89.8 6.3 2e-25 89.8 6.3 3.1 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 EGG41140.1 - 1.5e-09 38.1 1.3 1.5e-09 38.1 1.3 3.1 3 0 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD DUF4405 PF14358.6 EGG41140.1 - 7.3e-05 23.2 3.5 7.3e-05 23.2 3.5 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4405) UPF0542 PF15086.6 EGG41140.1 - 0.0053 16.6 0.2 0.0053 16.6 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0542 DUF3899 PF13038.6 EGG41140.1 - 0.29 11.7 0.0 0.29 11.7 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) PTPLA PF04387.14 EGG41140.1 - 6.7 6.4 11.3 1.8 8.2 0.4 3.2 2 2 1 3 3 3 0 Protein tyrosine phosphatase-like protein, PTPLA Rieske PF00355.26 EGG41141.1 - 6.3e-07 29.2 0.0 9.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 EGG41141.1 - 5.3e-05 22.9 1.0 5.3e-05 22.9 1.0 1.7 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 EGG41141.1 - 0.0016 17.8 0.1 0.0034 16.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_S8 PF00082.22 EGG41142.1 - 2.6e-35 122.2 0.0 6.7e-35 120.8 0.0 1.7 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EGG41142.1 - 3.3e-05 24.5 0.4 0.00076 20.1 0.0 2.8 2 0 0 2 2 2 1 Fn3-like domain DUF916 PF06030.12 EGG41142.1 - 0.0021 18.1 0.1 3.6 7.7 0.0 3.5 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF916) Romo1 PF10247.9 EGG41142.1 - 0.11 12.9 0.4 4.7 7.6 0.1 3.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 EF-hand_6 PF13405.6 EGG41142.1 - 0.53 10.4 3.9 3.5 7.8 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 EGG41142.1 - 1.3 8.7 5.6 7 6.5 0.0 3.4 3 0 0 3 3 3 0 EF hand Baculo_PEP_C PF04513.12 EGG41143.1 - 0.016 15.3 1.5 0.035 14.1 1.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGG41143.1 - 0.046 13.8 0.1 0.097 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EGG41143.1 - 0.067 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filamin PF00630.19 EGG41143.1 - 0.089 13.6 0.0 0.22 12.3 0.0 1.8 1 1 0 1 1 1 0 Filamin/ABP280 repeat NPV_P10 PF05531.12 EGG41143.1 - 0.38 11.2 2.1 27 5.3 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EGG41143.1 - 1.7 9.1 4.7 1.8 9.0 0.9 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ASH PF15780.5 EGG41144.1 - 0.087 13.0 0.0 0.39 10.9 0.0 2.1 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ThiF PF00899.21 EGG41145.1 - 7.5e-64 215.4 0.3 1.2e-63 214.8 0.3 1.2 1 0 0 1 1 1 1 ThiF family ThiS PF02597.20 EGG41145.1 - 2.9e-07 31.0 0.1 9.8e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 ThiS family Sacchrp_dh_NADP PF03435.18 EGG41145.1 - 0.0001 22.5 1.7 0.00045 20.5 1.7 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGG41145.1 - 0.0094 16.0 0.2 0.028 14.5 0.1 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGG41145.1 - 0.031 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 EGG41146.1 - 1.8e-71 241.0 0.5 2.1e-71 240.8 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.10 EGG41146.1 - 0.14 12.4 0.4 0.63 10.2 0.0 2.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal C1_2 PF03107.16 EGG41146.1 - 0.15 12.4 1.9 0.29 11.5 1.9 1.4 1 0 0 1 1 1 0 C1 domain zf-C2H2_11 PF16622.5 EGG41146.1 - 0.28 11.0 0.6 0.56 10.0 0.6 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type Cadherin_C_2 PF16492.5 EGG41147.1 - 0.11 13.2 0.0 0.43 11.4 0.0 1.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4446 PF14584.6 EGG41147.1 - 0.15 12.0 0.9 0.23 11.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) O-antigen_lig PF13425.6 EGG41147.1 - 0.26 10.0 0.8 0.31 9.8 0.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PRA-CH PF01502.18 EGG41148.1 - 2.7e-33 113.6 0.1 3.3e-33 113.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase His_biosynth PF00977.21 EGG41149.1 - 1.5e-84 283.0 1.2 1.7e-84 282.8 1.2 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 EGG41149.1 - 1.8e-08 33.9 0.0 3.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 EGG41149.1 - 2.5e-06 27.1 0.5 0.022 14.1 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 EGG41149.1 - 4.5e-05 22.9 0.1 0.021 14.2 0.1 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase DHO_dh PF01180.21 EGG41149.1 - 0.00017 20.9 0.1 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 EGG41149.1 - 0.0006 19.2 0.1 0.62 9.3 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EGG41149.1 - 0.0027 16.8 0.9 0.056 12.4 0.1 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.20 EGG41149.1 - 0.007 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain G3P_antiterm PF04309.12 EGG41149.1 - 0.011 15.2 0.2 0.74 9.2 0.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 EGG41149.1 - 0.027 13.9 0.2 0.085 12.3 0.1 1.8 2 0 0 2 2 2 0 PcrB family His_biosynth PF00977.21 EGG41150.1 - 1.3e-70 237.4 0.7 1.5e-70 237.3 0.7 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein IGPS PF00218.21 EGG41150.1 - 1.1e-05 24.8 0.0 0.0055 15.9 0.0 2.1 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.12 EGG41150.1 - 0.024 14.1 0.5 0.47 9.9 0.0 2.4 2 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 EGG41150.1 - 0.025 14.0 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.17 EGG41150.1 - 0.039 13.3 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Thiamine monophosphate synthase Dus PF01207.17 EGG41150.1 - 0.079 12.0 0.0 8.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) GATase PF00117.28 EGG41151.1 - 9.5e-26 90.7 0.0 1.2e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG41151.1 - 1.1e-05 25.3 0.0 0.0004 20.2 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 EGG41151.1 - 0.00022 21.1 0.0 0.0023 17.8 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGG41151.1 - 0.00091 18.9 0.0 0.0016 18.0 0.0 1.4 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain IGPD PF00475.18 EGG41152.1 - 1.8e-47 161.3 0.4 2.6e-47 160.8 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase ANF_receptor PF01094.28 EGG41152.1 - 0.064 12.3 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Hydrolase PF00702.26 EGG41153.1 - 2e-08 34.8 0.0 3.3e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG41153.1 - 3.1e-06 27.4 3.7 0.0003 20.9 3.7 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hypoth_Ymh PF09509.10 EGG41153.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Aminotran_1_2 PF00155.21 EGG41154.1 - 6.5e-42 144.0 0.0 7.8e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGG41154.1 - 0.031 13.2 0.0 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V LYTB PF02401.18 EGG41154.1 - 0.055 12.7 0.1 0.13 11.5 0.1 1.6 1 1 1 2 2 2 0 LytB protein Histidinol_dh PF00815.20 EGG41156.1 - 5.2e-139 463.8 0.0 6.1e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase ssDNA_DBD PF18333.1 EGG41156.1 - 0.013 15.6 0.1 0.03 14.4 0.1 1.6 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain DUF643 PF04867.12 EGG41156.1 - 5 7.8 10.5 0.095 13.3 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF643) HisG PF01634.18 EGG41157.1 - 8.1e-44 149.4 0.0 1.1e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EGG41157.1 - 6.6e-15 55.0 0.0 1.6e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain DUF2286 PF10051.9 EGG41158.1 - 0.03 14.1 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) HMG-CoA_red PF00368.18 EGG41159.1 - 1.2e-106 356.9 5.8 1.4e-106 356.6 5.8 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase GSDH PF07995.11 EGG41160.1 - 1.9e-79 267.4 0.0 2.7e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 EGG41160.1 - 0.014 15.6 0.2 3.6 8.1 0.0 4.1 4 0 0 4 4 4 0 Two component regulator propeller NHL PF01436.21 EGG41160.1 - 0.17 12.0 0.1 5.3 7.3 0.0 3.3 3 0 0 3 3 3 0 NHL repeat DUF1743 PF08489.11 EGG41162.1 - 1.6e-33 115.2 0.0 5.1e-32 110.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1743) DZR PF12773.7 EGG41162.1 - 0.07 13.2 1.3 0.12 12.4 1.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 EGG41162.1 - 2.3 8.3 8.4 1 9.4 1.7 2.8 1 1 1 2 2 2 0 BED zinc finger Diphthamide_syn PF01866.17 EGG41163.1 - 2.7e-64 217.5 0.0 3e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_1 PF00515.28 EGG41164.1 - 2.8e-20 71.2 7.5 2.5e-08 33.4 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG41164.1 - 2.6e-17 61.5 1.3 8.5e-05 22.4 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG41164.1 - 2.2e-12 47.3 0.0 0.00013 22.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG41164.1 - 2.1e-11 43.1 2.4 6.9e-06 25.9 0.1 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG41164.1 - 6e-10 39.3 0.0 0.0094 16.2 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGG41164.1 - 8e-09 35.6 0.1 0.53 11.0 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG41164.1 - 1.1e-08 34.6 3.1 0.0016 18.1 0.1 4.6 5 0 0 5 5 5 2 TPR repeat Fis1_TPR_C PF14853.6 EGG41164.1 - 6e-08 32.6 0.4 0.086 12.9 0.1 4.2 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGG41164.1 - 1.2e-07 31.9 0.0 0.12 13.3 0.0 4.1 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG41164.1 - 3.7e-07 30.7 0.0 0.00011 22.8 0.0 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG41164.1 - 5.1e-07 29.8 1.5 0.0087 16.3 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGG41164.1 - 2e-06 27.4 0.0 0.085 12.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG41164.1 - 6.3e-06 25.9 0.0 0.11 12.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG41164.1 - 1.7e-05 24.8 0.0 0.00069 19.7 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG41164.1 - 2.2e-05 24.5 4.1 0.016 15.5 0.2 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGG41164.1 - 0.00062 19.7 2.3 0.18 11.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 EGG41164.1 - 0.0016 18.5 0.5 3.3 8.1 0.0 4.1 4 0 0 4 4 4 1 PPR repeat DUF4919 PF16266.5 EGG41164.1 - 0.0092 16.0 0.1 0.1 12.5 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4919) Sec16_C PF12931.7 EGG41164.1 - 0.055 13.1 0.0 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 SSXT PF05030.12 EGG41164.1 - 0.081 12.6 1.1 9.1 6.0 0.1 3.1 2 1 1 3 3 3 0 SSXT protein (N-terminal region) B1 PF02246.15 EGG41164.1 - 0.095 12.8 0.1 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein L b1 domain ATP13 PF12921.7 EGG41164.1 - 0.095 12.6 0.1 2.1 8.3 0.0 2.7 1 1 1 3 3 3 0 Mitochondrial ATPase expression DUF1106 PF06523.11 EGG41164.1 - 2.5 8.2 5.6 19 5.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1106) ADH_zinc_N PF00107.26 EGG41165.1 - 9.2e-26 90.3 0.0 1.6e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG41165.1 - 1.7e-23 82.6 0.2 2.8e-23 81.9 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGG41165.1 - 2e-17 64.5 0.0 3.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 EGG41165.1 - 0.023 14.9 0.6 0.13 12.5 0.1 2.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Big_3_4 PF13754.6 EGG41165.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function YajC PF02699.15 EGG41165.1 - 0.42 10.5 1.8 26 4.8 0.0 3.6 4 0 0 4 4 4 0 Preprotein translocase subunit ECR1_N PF14382.6 EGG41166.1 - 0.00027 20.7 0.0 0.0008 19.2 0.0 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Prok-RING_1 PF14446.6 EGG41166.1 - 1.1 9.3 5.1 0.34 10.9 1.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PDT PF00800.18 EGG41167.1 - 7.6e-58 195.3 0.1 9.8e-58 195.0 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EGG41167.1 - 4.3e-05 23.2 0.0 7.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain TrbC PF04956.13 EGG41168.1 - 2.9 8.2 5.9 5.1 7.4 0.2 2.6 3 0 0 3 3 3 0 TrbC/VIRB2 family IMPDH PF00478.25 EGG41169.1 - 4.1e-146 486.4 9.9 5.3e-146 486.0 9.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGG41169.1 - 4.8e-23 81.4 1.6 2.6e-10 40.6 0.1 3.7 4 0 0 4 4 4 2 CBS domain NMO PF03060.15 EGG41169.1 - 4.4e-09 36.2 8.8 6.5e-05 22.5 4.9 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EGG41169.1 - 3.6e-06 26.6 1.4 0.027 13.9 0.1 2.7 1 1 1 2 2 2 2 Histidine biosynthesis protein FMN_dh PF01070.18 EGG41169.1 - 1.5e-05 24.2 9.5 6.7e-05 22.1 9.5 2.1 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EGG41169.1 - 0.00089 18.6 5.6 0.0011 18.2 1.4 2.3 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.14 EGG41169.1 - 0.0012 18.1 1.1 0.0012 18.1 1.1 2.1 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase PK PF00224.21 EGG41169.1 - 0.0013 17.7 0.4 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain ThiG PF05690.14 EGG41169.1 - 0.041 13.2 3.8 0.045 13.1 1.3 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 EGG41169.1 - 0.049 13.1 1.2 0.14 11.6 1.1 1.8 1 1 0 1 1 1 0 KDPG and KHG aldolase PEP_mutase PF13714.6 EGG41169.1 - 0.058 12.8 1.5 0.092 12.2 0.2 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Pterin_bind PF00809.22 EGG41170.1 - 5.2e-52 177.0 0.1 1e-51 176.0 0.1 1.5 1 1 0 1 1 1 1 Pterin binding enzyme MAF_flag10 PF01973.18 EGG41171.1 - 8.6e-36 123.2 0.7 1.3e-35 122.6 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPK_catalytic PF04263.16 EGG41171.1 - 0.095 12.7 0.1 0.23 11.5 0.1 1.8 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF2443 PF10398.9 EGG41172.1 - 0.47 10.5 6.3 8 6.6 1.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2443) GATase PF00117.28 EGG41173.1 - 9.1e-43 146.2 0.0 1.3e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EGG41173.1 - 1.2e-34 118.2 0.1 2.5e-34 117.2 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 EGG41173.1 - 6.7e-12 45.0 0.1 6.5e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EGG41173.1 - 3.1e-08 33.6 0.1 1.4e-07 31.5 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.14 EGG41173.1 - 4.2e-06 26.5 0.0 0.00036 20.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EGG41173.1 - 0.00018 20.4 0.0 0.0047 15.8 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 EGG41173.1 - 0.0097 15.4 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 EGG41173.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 PP-loop family bact-PGI_C PF10432.9 EGG41174.1 - 3e-35 121.5 0.0 5.6e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 EGG41174.1 - 6.9e-09 35.6 0.1 1.3e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 SIS domain CTP_transf_3 PF02348.19 EGG41175.1 - 3e-18 66.6 0.2 4.3e-18 66.1 0.2 1.2 1 1 0 1 1 1 1 Cytidylyltransferase Arg_repressor PF01316.21 EGG41175.1 - 0.009 15.8 0.1 0.024 14.4 0.1 1.8 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DUF2023 PF09633.10 EGG41175.1 - 0.016 15.3 0.2 0.2 11.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2023) Methyltransf_21 PF05050.12 EGG41176.1 - 0.021 14.8 0.4 0.038 14.0 0.4 1.5 1 1 0 1 1 1 0 Methyltransferase FkbM domain LAGLIDADG_1 PF00961.19 EGG41176.1 - 2.7 9.0 12.6 1.2 10.2 7.9 2.3 1 1 1 2 2 2 0 LAGLIDADG endonuclease Radical_SAM PF04055.21 EGG41178.1 - 1.7e-14 54.5 0.0 1.2e-13 51.8 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 EGG41178.1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain Flavodoxin_3 PF12641.7 EGG41178.1 - 0.022 14.5 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain MAF_flag10 PF01973.18 EGG41179.1 - 6.9e-17 61.7 0.1 1.2e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF115 Epimerase PF01370.21 EGG41180.1 - 5.9e-37 127.4 0.0 6.4e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG41180.1 - 1.3e-36 126.7 0.0 1.4e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGG41180.1 - 6.4e-28 97.5 0.7 7.6e-28 97.3 0.7 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG41180.1 - 1.4e-19 70.3 0.0 1.6e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGG41180.1 - 5.9e-18 65.0 1.8 1.6e-15 57.0 1.8 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EGG41180.1 - 5.6e-16 58.5 0.8 1.4e-15 57.2 0.8 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGG41180.1 - 5.8e-16 58.9 0.0 6.9e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGG41180.1 - 1.7e-07 31.5 0.1 2.3e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EGG41180.1 - 1.5e-06 28.0 0.2 2.8e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGG41180.1 - 2.1e-05 24.1 0.0 3.2e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG41180.1 - 6e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 EGG41180.1 - 0.00032 20.8 0.2 0.00059 20.0 0.2 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 EGG41180.1 - 0.013 15.8 0.1 0.021 15.1 0.1 1.5 1 1 0 1 1 1 0 TrkA-N domain DUF5104 PF17117.5 EGG41180.1 - 0.039 14.4 2.3 0.062 13.8 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) GDP_Man_Dehyd PF16363.5 EGG41181.1 - 6.7e-07 29.0 0.0 1.2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG41181.1 - 0.0023 17.1 0.0 0.0026 17.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CdiI PF07262.11 EGG41181.1 - 0.052 13.3 0.1 0.076 12.8 0.0 1.4 1 1 0 1 1 1 0 CDI immunity protein Radical_SAM PF04055.21 EGG41182.1 - 1.9e-10 41.4 0.1 5.3e-10 39.9 0.0 1.9 2 1 0 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 EGG41182.1 - 3.8e-08 33.7 3.6 8.5e-07 29.4 1.0 3.4 2 1 0 2 2 2 1 Iron-sulfur cluster-binding domain Fer4_14 PF13394.6 EGG41182.1 - 0.0014 18.7 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EGG41182.1 - 0.016 15.5 0.1 0.037 14.3 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain DnaT PF17948.1 EGG41182.1 - 0.083 12.6 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 DnaT DNA-binding domain Cupin_7 PF12973.7 EGG41183.1 - 0.0014 18.5 0.1 0.0017 18.2 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 EGG41183.1 - 0.024 14.3 0.2 0.034 13.9 0.2 1.3 1 0 0 1 1 1 0 Cupin domain GDPD PF03009.17 EGG41184.1 - 0.0051 16.6 0.0 0.08 12.6 0.0 2.0 1 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGG41184.1 - 0.03 14.8 0.0 0.067 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family NTP_transf_3 PF12804.7 EGG41185.1 - 4.2e-05 24.0 0.0 5.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGG41185.1 - 0.02 14.7 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CRC_subunit PF08624.10 EGG41185.1 - 0.028 14.8 0.0 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit PGM_PMM_III PF02880.16 EGG41186.1 - 1.3e-09 38.2 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGG41186.1 - 1.8e-08 34.9 0.0 3.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 EGG41186.1 - 9.3e-07 28.6 0.5 1.8e-06 27.7 0.5 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGG41186.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 EGG41187.1 - 6.1e-09 35.7 0.0 1.2e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I NAD_synthase PF02540.17 EGG41187.1 - 0.2 10.8 0.8 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 NAD synthase IL1_propep PF02394.16 EGG41187.1 - 0.23 12.4 1.7 2.6 9.0 0.6 2.2 1 1 1 2 2 2 0 Interleukin-1 propeptide Sulfatase PF00884.23 EGG41188.1 - 9.9e-28 97.4 0.0 2e-27 96.4 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGG41188.1 - 1.8e-07 31.1 0.0 0.016 14.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGG41188.1 - 0.0011 18.4 0.0 0.0035 16.7 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF4994 PF16385.5 EGG41188.1 - 0.0012 18.8 0.2 0.0034 17.2 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 EGG41188.1 - 0.0013 19.0 1.1 0.0022 18.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 EGG41188.1 - 0.11 13.2 0.2 0.24 12.1 0.2 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase WavE PF07507.11 EGG41189.1 - 6.8e-16 58.3 3.3 2.7e-14 53.0 3.3 2.2 1 1 0 1 1 1 1 WavE lipopolysaccharide synthesis Viral_env_E26 PF11050.8 EGG41190.1 - 0.00057 19.3 6.5 0.0061 15.9 5.4 2.3 1 1 1 2 2 2 1 Virus envelope protein E26 CMAS PF02353.20 EGG41190.1 - 0.0011 18.3 1.9 0.0016 17.8 1.9 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Kri1 PF05178.12 EGG41190.1 - 0.027 15.0 0.5 0.067 13.8 0.5 1.7 1 0 0 1 1 1 0 KRI1-like family DUF5063 PF16702.5 EGG41190.1 - 0.073 13.5 0.2 0.11 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) Methyltransf_31 PF13847.6 EGG41190.1 - 0.16 11.7 7.6 0.13 12.1 1.5 2.5 1 1 2 3 3 3 0 Methyltransferase domain TFIIF_alpha PF05793.12 EGG41190.1 - 0.34 9.4 8.8 0.13 10.8 5.2 2.0 2 1 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Radical_SAM PF04055.21 EGG41191.1 - 2.7e-13 50.7 0.1 8.3e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 EGG41191.1 - 1.9e-05 24.7 0.0 0.00019 21.5 0.0 2.5 2 0 0 2 2 2 1 B12 binding domain Y_phosphatase2 PF03162.13 EGG41191.1 - 0.021 14.4 0.1 0.054 13.1 0.1 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family CSN8_PSD8_EIF3K PF10075.9 EGG41191.1 - 0.051 13.5 0.0 7.1 6.6 0.0 2.7 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family NTP_transf_3 PF12804.7 EGG41192.1 - 4.3e-10 40.2 0.0 4.8e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EGG41192.1 - 4.4e-10 39.6 0.0 4.7e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 EGG41192.1 - 0.00028 20.7 0.0 0.0003 20.6 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NUDIX PF00293.28 EGG41194.1 - 7.3e-13 48.7 0.0 8.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain LPD16 PF18830.1 EGG41194.1 - 0.091 12.7 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 16 TylF PF05711.11 EGG41195.1 - 2e-10 40.4 0.0 2.3e-08 33.6 0.0 2.1 1 1 1 2 2 2 2 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EGG41195.1 - 1.1e-08 36.0 0.0 2.5e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AAA_14 PF13173.6 EGG41195.1 - 0.048 13.7 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain NTP_transf_3 PF12804.7 EGG41196.1 - 5.9e-06 26.7 0.0 8.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGG41196.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TPP_enzyme_C PF02775.21 EGG41197.1 - 2.8e-16 59.7 0.0 7.7e-16 58.2 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 EGG41198.1 - 2.9e-07 30.3 0.0 3.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transket_pyr PF02779.24 EGG41198.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 1 0 1 1 1 0 Transketolase, pyrimidine binding domain PEP_mutase PF13714.6 EGG41199.1 - 4.2e-65 219.5 0.1 5e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGG41199.1 - 1.3e-06 27.2 0.0 3.9e-06 25.6 0.0 1.6 1 1 1 2 2 2 1 Isocitrate lyase family PucR PF07905.11 EGG41199.1 - 0.039 14.2 0.0 0.93 9.8 0.0 2.6 2 1 0 2 2 2 0 Purine catabolism regulatory protein-like family Fe-ADH PF00465.19 EGG41200.1 - 2.7e-49 167.9 0.0 4.7e-49 167.2 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGG41200.1 - 3.8e-20 72.6 0.0 5.3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EGG41200.1 - 8.1e-06 25.2 0.0 0.024 13.8 0.0 2.1 2 0 0 2 2 2 2 3-dehydroquinate synthase ATP-cone PF03477.16 EGG41200.1 - 5.4 7.7 5.7 20 5.8 0.5 3.4 3 1 0 3 3 3 0 ATP cone domain HSR PF03172.13 EGG41201.1 - 0.056 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 HSR domain adh_short_C2 PF13561.6 EGG41202.1 - 2.8e-44 151.4 0.0 3.4e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG41202.1 - 1.1e-38 132.7 0.2 1.4e-38 132.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EGG41202.1 - 1.3e-09 37.9 0.0 1.8e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGG41202.1 - 2.1e-09 37.5 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGG41202.1 - 6.4e-06 25.8 0.1 1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGG41202.1 - 0.001 18.1 0.6 0.0014 17.7 0.6 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Med16 PF11635.8 EGG41202.1 - 0.027 12.4 0.4 0.11 10.4 0.4 1.7 2 0 0 2 2 2 0 Mediator complex subunit 16 DUF1776 PF08643.10 EGG41202.1 - 0.033 13.6 0.1 0.14 11.5 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 EGG41202.1 - 0.071 13.4 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGG41202.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGG41202.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CTP_transf_3 PF02348.19 EGG41203.1 - 6.2e-35 121.1 1.7 7.8e-35 120.8 1.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DUF3969 PF13108.6 EGG41203.1 - 0.0048 16.9 1.7 0.084 12.9 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3969) NTP_transf_3 PF12804.7 EGG41203.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.7 2 1 0 2 2 2 0 MobA-like NTP transferase domain DUF3877 PF12993.7 EGG41203.1 - 0.022 14.6 3.4 2 8.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DegT_DnrJ_EryC1 PF01041.17 EGG41204.1 - 4.9e-97 325.5 0.0 5.5e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGG41204.1 - 1.8e-10 40.6 0.1 2.7e-10 40.0 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG41204.1 - 5.9e-10 38.9 0.0 8.1e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EGG41204.1 - 7.9e-09 34.7 0.3 9.4e-09 34.4 0.3 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 EGG41204.1 - 1.3e-05 24.0 0.1 2.4e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGG41204.1 - 0.00054 19.0 0.0 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF4910 PF16254.5 EGG41205.1 - 1.3e-106 355.0 0.1 1.6e-106 354.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4910) DUF2172 PF09940.9 EGG41205.1 - 6e-41 138.8 0.3 1.3e-40 137.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2172) HTH_47 PF16221.5 EGG41205.1 - 4.6e-22 77.4 0.0 8.7e-22 76.5 0.0 1.5 1 0 0 1 1 1 1 winged helix-turn-helix Peptidase_M28 PF04389.17 EGG41205.1 - 5.2e-05 23.0 0.0 8.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF4423 PF14394.6 EGG41205.1 - 0.00075 19.3 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) RepL PF05732.11 EGG41205.1 - 0.0041 16.6 0.5 0.0091 15.4 0.5 1.6 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_36 PF13730.6 EGG41205.1 - 0.017 15.1 0.2 0.083 12.9 0.2 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EGG41205.1 - 0.024 14.2 1.7 0.12 12.0 0.4 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Antibiotic_NAT PF02522.14 EGG41206.1 - 3.4e-45 154.5 0.0 3.9e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase TylF PF05711.11 EGG41207.1 - 9.8e-11 41.4 0.0 1.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EGG41207.1 - 0.00073 20.5 0.0 0.0015 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TcpS PF17456.2 EGG41207.1 - 0.099 12.7 0.1 17 5.4 0.0 2.2 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S CmcI PF04989.12 EGG41207.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 EGG41208.1 - 2.8e-09 37.9 0.0 4.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG41208.1 - 0.00036 20.4 0.0 0.00067 19.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG41208.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_17 PF12692.7 EGG41208.1 - 0.03 14.3 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Cons_hypoth95 PF03602.15 EGG41208.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Nup35_RRM PF05172.13 EGG41208.1 - 0.08 12.9 0.4 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Metallophos_2 PF12850.7 EGG41208.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Methyltransf_25 PF13649.6 EGG41208.1 - 0.18 12.5 0.0 0.59 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Lactamase_B_3 PF13483.6 EGG41209.1 - 6.4e-15 55.4 0.0 5.8e-14 52.3 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EGG41209.1 - 3.5e-06 26.7 0.0 9.8e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NeuB PF03102.14 EGG41210.1 - 9.5e-37 126.7 0.3 2.3e-36 125.5 0.3 1.6 1 1 0 1 1 1 1 NeuB family Acetyltransf_3 PF13302.7 EGG41211.1 - 5.8e-08 33.5 0.0 6.8e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG41211.1 - 0.0001 22.6 0.0 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG41211.1 - 0.0037 17.5 0.0 0.0045 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family His_binding PF02098.16 EGG41211.1 - 0.039 14.0 0.1 0.07 13.2 0.1 1.5 1 1 0 1 1 1 0 Tick histamine binding protein Polysacc_synt_2 PF02719.15 EGG41212.1 - 3.4e-98 328.4 0.1 4e-98 328.2 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGG41212.1 - 5.6e-30 104.6 0.1 4.4e-29 101.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG41212.1 - 1.3e-22 80.1 0.2 3.9e-20 72.0 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG41212.1 - 2.4e-18 66.6 0.1 1.3e-17 64.2 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGG41212.1 - 1.5e-16 60.3 0.0 1.1e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGG41212.1 - 2.1e-12 47.3 0.0 3.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGG41212.1 - 1.3e-10 40.9 1.4 5.2e-08 32.4 0.7 3.0 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 EGG41212.1 - 2.8e-07 30.2 0.0 6.1e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EGG41212.1 - 2.8e-07 30.3 0.0 4.2e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 EGG41212.1 - 1.6e-06 28.1 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EGG41212.1 - 1.2e-05 25.4 0.2 0.00027 21.0 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGG41212.1 - 6.5e-05 23.4 0.0 0.00022 21.8 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EGG41212.1 - 0.00014 22.1 0.1 0.0059 16.9 0.0 2.8 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EGG41212.1 - 0.0032 17.9 0.0 0.041 14.3 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGG41212.1 - 0.018 15.3 0.1 0.075 13.3 0.1 2.1 2 1 0 2 2 2 0 TrkA-N domain Epimerase_2 PF02350.19 EGG41213.1 - 7.9e-07 28.2 0.4 1.1e-06 27.8 0.4 1.2 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyphos_transf PF04464.14 EGG41213.1 - 0.00089 18.3 2.0 0.0011 18.0 0.3 1.9 2 0 0 2 2 2 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Glyco_trans_1_4 PF13692.6 EGG41213.1 - 0.0076 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Amidase_3 PF01520.18 EGG41213.1 - 0.058 13.5 0.4 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase SAS4 PF15460.6 EGG41213.1 - 0.061 13.4 0.8 0.47 10.6 0.1 2.8 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 IL7 PF01415.16 EGG41214.1 - 0.034 14.2 0.5 0.094 12.8 0.1 1.8 2 0 0 2 2 2 0 Interleukin 7/9 family Methyltransf_14 PF08484.11 EGG41215.1 - 3.7e-54 182.8 0.0 9.7e-54 181.5 0.0 1.7 2 0 0 2 2 2 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 EGG41215.1 - 2.9e-18 65.9 0.3 5.5e-18 65.0 0.3 1.5 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 EGG41215.1 - 7.6e-14 51.9 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41215.1 - 5.4e-06 27.1 0.1 1.1e-05 26.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41215.1 - 0.00052 20.6 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG41215.1 - 0.091 12.5 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CTXphi_pIII-N1 PF16710.5 EGG41215.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Glycos_transf_2 PF00535.26 EGG41216.1 - 1.2e-12 47.9 0.0 2.7e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGG41216.1 - 1.6e-11 44.5 0.0 3.4e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGG41216.1 - 0.00021 21.3 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGG41217.1 - 6.8e-11 42.3 0.4 7.6e-11 42.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGG41217.1 - 0.00026 21.0 0.0 0.00029 20.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Methyltransf_31 PF13847.6 EGG41218.1 - 1.2e-21 77.1 0.7 3.2e-21 75.7 0.4 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG41218.1 - 1.7e-14 54.0 0.0 3.6e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG41218.1 - 2.5e-14 53.8 0.0 4.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41218.1 - 1.4e-13 51.4 0.1 2.8e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41218.1 - 3e-12 47.0 0.0 6.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGG41218.1 - 2.8e-06 26.5 0.0 4.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 EGG41218.1 - 7.8e-06 25.5 0.6 1.5e-05 24.6 0.2 1.7 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.18 EGG41218.1 - 9.9e-06 25.2 0.1 9.4e-05 22.0 0.1 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 EGG41218.1 - 0.00027 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EGG41218.1 - 0.00037 19.7 0.1 0.001 18.2 0.1 1.6 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_2 PF00891.18 EGG41218.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EGG41218.1 - 0.0038 16.6 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGG41218.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGG41218.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Rsm22 PF09243.10 EGG41218.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RmlD_sub_bind PF04321.17 EGG41219.1 - 3.9e-59 200.1 0.0 7.6e-59 199.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGG41219.1 - 2.5e-24 86.1 0.3 3.6e-24 85.6 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG41219.1 - 2.1e-14 53.7 0.1 3.3e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG41219.1 - 5.2e-11 42.2 2.6 3.1e-10 39.7 2.6 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGG41219.1 - 5.2e-10 38.9 0.1 1.6e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EGG41219.1 - 1.2e-07 31.0 3.5 4.1e-07 29.3 3.5 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGG41219.1 - 0.0051 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EGG41219.1 - 0.12 12.5 0.1 0.5 10.5 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 EGG41219.1 - 0.21 11.0 0.7 5.8 6.3 0.2 2.5 2 1 0 2 2 2 0 short chain dehydrogenase ACPS PF01648.20 EGG41220.1 - 7.6e-16 58.3 0.1 9.3e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily AMP-binding PF00501.28 EGG41221.1 - 2.8e-76 256.8 0.0 3.4e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG41221.1 - 6.7e-13 49.4 0.1 4.3e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 EGG41222.1 - 1.2e-11 43.8 14.6 1.1e-05 25.0 8.1 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGG41222.1 - 2.5e-09 36.7 14.3 0.002 17.8 10.7 3.5 3 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF5325 PF17259.2 EGG41222.1 - 0.21 11.5 3.4 0.48 10.3 3.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) NAD_synthase PF02540.17 EGG41223.1 - 1.4e-54 184.8 0.3 2.6e-27 95.5 0.0 2.0 1 1 1 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 EGG41223.1 - 0.00039 19.3 0.0 0.00073 18.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 EGG41223.1 - 0.0014 18.1 0.0 0.0063 16.0 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 EGG41223.1 - 0.0074 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase UPF0240 PF06784.11 EGG41223.1 - 0.034 14.2 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) MerR-DNA-bind PF09278.11 EGG41224.1 - 0.035 14.6 0.1 1.1 9.9 0.1 2.1 1 1 0 1 1 1 0 MerR, DNA binding SMC_ScpB PF04079.16 EGG41224.1 - 0.058 13.0 0.1 0.068 12.8 0.1 1.1 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB NAD_synthase PF02540.17 EGG41224.1 - 0.063 12.4 0.3 0.073 12.2 0.3 1.0 1 0 0 1 1 1 0 NAD synthase GDP_Man_Dehyd PF16363.5 EGG41225.1 - 9.1e-74 248.8 0.0 1e-73 248.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG41225.1 - 4.8e-57 193.2 0.0 5.7e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG41225.1 - 1.9e-16 59.9 0.0 2.4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG41225.1 - 3.8e-16 59.0 0.0 5.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG41225.1 - 2.4e-14 53.2 0.1 2.5e-13 49.8 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGG41225.1 - 3.5e-14 52.6 0.0 3.3e-12 46.1 0.0 2.9 2 1 1 3 3 3 1 Male sterility protein DUF2527 PF10736.9 EGG41225.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) PIEZO PF15917.5 EGG41225.1 - 0.085 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Piezo Sacchrp_dh_NADP PF03435.18 EGG41225.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain dTDP_sugar_isom PF00908.17 EGG41226.1 - 6.7e-21 74.7 0.0 8.9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Cupin_2 PF07883.11 EGG41226.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.7 1 1 0 1 1 1 0 Cupin domain Hydrolase_3 PF08282.12 EGG41227.1 - 9.3e-16 58.3 1.5 3.3e-15 56.5 0.5 1.9 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG41227.1 - 1.7e-08 35.0 0.2 5.4e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG41227.1 - 0.0012 18.9 0.8 0.0036 17.4 0.2 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG41227.1 - 0.0038 17.7 0.1 0.037 14.4 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGG41227.1 - 0.0068 16.5 0.0 0.092 12.9 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HTH_26 PF13443.6 EGG41227.1 - 0.015 15.7 0.0 0.074 13.5 0.0 2.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain NeuB PF03102.14 EGG41228.1 - 3.9e-67 226.2 0.4 4.5e-67 226.0 0.4 1.0 1 0 0 1 1 1 1 NeuB family SIS_2 PF13580.6 EGG41229.1 - 6.6e-26 91.0 0.3 9.9e-26 90.4 0.3 1.2 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 EGG41229.1 - 1.6e-06 28.0 0.3 1.5e-05 24.9 0.0 2.1 1 1 1 2 2 2 1 SIS domain TylF PF05711.11 EGG41230.1 - 7.4e-11 41.8 0.2 4.5e-10 39.2 0.2 2.0 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EGG41230.1 - 1.4e-05 26.0 0.0 2.3e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AP_endonuc_2 PF01261.24 EGG41232.1 - 1.1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4434 PF14488.6 EGG41232.1 - 0.0027 17.7 0.8 0.066 13.2 0.7 2.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4434) adh_short_C2 PF13561.6 EGG41233.1 - 1.9e-33 115.9 0.0 2.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG41233.1 - 8.5e-18 64.5 0.0 6.8e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGG41233.1 - 1.2e-05 24.6 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGG41233.1 - 0.00011 21.7 0.0 0.00022 20.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 EGG41234.1 - 3.2e-20 73.1 0.0 4.8e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF4295 PF14128.6 EGG41234.1 - 0.03 14.1 0.4 0.12 12.2 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4295) Semialdhyde_dh PF01118.24 EGG41234.1 - 0.037 14.5 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Rhabdo_glycop PF00974.18 EGG41234.1 - 0.071 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein F420_oxidored PF03807.17 EGG41234.1 - 0.18 12.4 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 EGG41235.1 - 1.4e-39 135.6 0.0 2.1e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG41235.1 - 1.2e-32 113.4 0.0 2.6e-32 112.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG41235.1 - 2.4e-07 30.8 0.0 3.2e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF900 PF05990.12 EGG41235.1 - 0.0033 17.0 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Cmc1 PF08583.10 EGG41235.1 - 0.042 13.9 0.5 0.079 13.0 0.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like SET_assoc PF11767.8 EGG41235.1 - 0.11 12.2 0.7 0.7 9.6 0.1 2.2 1 1 1 2 2 2 0 Histone lysine methyltransferase SET associated Methyltransf_23 PF13489.6 EGG41236.1 - 4.4e-23 81.9 0.0 7e-23 81.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG41236.1 - 2.9e-22 79.1 0.0 4.1e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG41236.1 - 1.6e-17 63.9 0.0 1.2e-16 61.1 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41236.1 - 3.6e-17 62.8 0.0 7.9e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41236.1 - 9.3e-16 58.4 0.0 2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGG41236.1 - 3e-11 42.8 0.0 4.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EGG41236.1 - 1.1e-09 38.1 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EGG41236.1 - 4.7e-09 35.9 0.0 7.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGG41236.1 - 4e-08 33.0 0.0 5.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EGG41236.1 - 2.2e-06 27.4 0.0 9.1e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 EGG41236.1 - 7e-06 25.6 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 EGG41236.1 - 2.8e-05 23.7 0.7 0.08 12.4 0.1 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain DREV PF05219.12 EGG41236.1 - 3.7e-05 23.0 0.0 7.8e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase NodS PF05401.11 EGG41236.1 - 6.3e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EGG41236.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EGG41236.1 - 0.0005 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) N6_N4_Mtase PF01555.18 EGG41236.1 - 0.0011 18.7 0.3 0.0021 17.8 0.1 1.6 2 0 0 2 2 2 1 DNA methylase FtsJ PF01728.19 EGG41236.1 - 0.0043 17.2 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EGG41236.1 - 0.0085 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EGG41236.1 - 0.0086 15.8 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_2 PF00891.18 EGG41236.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 EGG41236.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 EGG41236.1 - 0.028 14.8 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.12 EGG41236.1 - 0.033 13.4 0.1 0.12 11.6 0.0 1.7 1 1 1 2 2 2 0 N2227-like protein Methyltransf_4 PF02390.17 EGG41236.1 - 0.036 13.5 0.0 0.08 12.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PMT_2 PF13231.6 EGG41237.1 - 5.4e-09 36.5 15.8 5.4e-09 36.5 15.8 3.3 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 EGG41237.1 - 0.0016 18.1 12.9 0.0016 18.1 12.9 3.2 2 2 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase HA1 PF18239.1 EGG41237.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Hemagglutinin I SLATT_6 PF18169.1 EGG41237.1 - 0.14 11.7 0.2 0.14 11.7 0.2 3.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 AIF-MLS PF14962.6 EGG41237.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence STT3 PF02516.14 EGG41237.1 - 5.7 5.7 34.9 0.69 8.8 19.0 2.3 1 1 0 2 2 2 0 Oligosaccharyl transferase STT3 subunit DUF2206 PF09971.9 EGG41240.1 - 0.027 13.2 2.9 0.038 12.7 2.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) NTP_transferase PF00483.23 EGG41241.1 - 2.3e-55 187.9 0.0 2.8e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGG41241.1 - 1.7e-08 35.0 0.0 2.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EGG41241.1 - 2.5e-08 33.3 18.2 3.3e-06 26.6 2.7 3.9 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGG41241.1 - 0.0068 16.1 3.3 0.0068 16.1 3.3 3.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 EGG41241.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.12 EGG41241.1 - 0.85 8.5 4.8 2.8 6.8 4.8 1.7 1 1 0 1 1 1 0 L-fucokinase DUF3473 PF11959.8 EGG41242.1 - 2.9e-33 114.7 0.0 4.3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) Polysacc_deac_1 PF01522.21 EGG41242.1 - 1.2e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase UAE_UbL PF14732.6 EGG41242.1 - 0.16 12.6 0.0 0.81 10.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Capsule_synth PF05159.14 EGG41243.1 - 6.8e-16 58.6 0.5 1e-15 58.0 0.5 1.2 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein Epimerase_2 PF02350.19 EGG41243.1 - 0.027 13.3 0.0 0.078 11.8 0.0 1.8 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_1_4 PF13692.6 EGG41244.1 - 3.5e-11 43.6 0.0 6.2e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGG41244.1 - 3.7e-06 27.2 0.0 9.8e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGG41244.1 - 0.0019 17.8 0.0 0.0049 16.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 GDP_Man_Dehyd PF16363.5 EGG41245.1 - 3.3e-109 365.3 0.0 5.4e-109 364.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG41245.1 - 3.5e-55 187.1 0.0 4.4e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG41245.1 - 4.6e-06 25.9 0.0 6.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG41245.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 EGG41245.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EGG41246.1 - 3.6e-52 177.8 1.3 2.5e-51 175.1 1.3 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG41246.1 - 5.2e-51 173.4 0.1 6.3e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG41246.1 - 2.6e-24 85.8 0.0 3.4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGG41246.1 - 2.3e-18 66.2 0.6 2.3e-18 66.2 0.6 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG41246.1 - 4.7e-17 62.0 0.2 2e-11 43.5 0.2 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EGG41246.1 - 3.8e-16 59.1 1.6 1.3e-14 54.0 1.6 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGG41246.1 - 0.0003 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AdoMet_MTase PF07757.13 EGG41246.1 - 0.0034 17.7 0.0 1.5 9.2 0.0 2.7 2 1 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase adh_short PF00106.25 EGG41246.1 - 0.023 14.2 0.0 0.15 11.5 0.0 2.2 3 0 0 3 3 3 0 short chain dehydrogenase NmrA PF05368.13 EGG41246.1 - 0.057 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 EGG41246.1 - 0.12 12.2 0.0 10 6.0 0.0 2.2 1 1 1 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 EGG41247.1 - 7.4e-92 307.6 1.7 9.6e-92 307.2 1.7 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGG41247.1 - 1.4e-21 77.1 0.2 2.6e-20 72.9 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG41247.1 - 2.8e-18 65.9 1.7 3.8e-18 65.5 1.7 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG41247.1 - 5.3e-16 58.6 0.0 1.6e-14 53.7 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGG41247.1 - 1.1e-14 54.5 0.3 2e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGG41247.1 - 1.7e-10 41.1 0.2 2.6e-10 40.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGG41247.1 - 1.5e-07 30.8 1.4 5.7e-06 25.7 1.3 2.6 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.13 EGG41247.1 - 4e-06 26.6 1.4 9.2e-06 25.4 1.4 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGG41247.1 - 2.2e-05 24.0 1.1 3.9e-05 23.2 1.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EGG41247.1 - 0.007 16.6 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EGG41247.1 - 0.012 15.5 0.1 0.027 14.4 0.0 1.6 1 1 0 1 1 1 0 KR domain F420_oxidored PF03807.17 EGG41247.1 - 0.022 15.3 0.3 0.35 11.5 0.1 2.7 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EGG41248.1 - 2.5e-42 145.0 0.0 3.5e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG41248.1 - 9.9e-35 120.5 0.2 3e-32 112.4 0.0 2.2 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGG41248.1 - 4e-21 75.2 0.4 2.4e-17 62.8 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGG41248.1 - 1.2e-18 67.3 0.1 1.4e-15 57.2 0.0 2.6 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGG41248.1 - 7.1e-18 64.7 0.0 1e-14 54.4 0.0 2.8 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EGG41248.1 - 5.4e-16 58.5 0.0 6.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGG41248.1 - 1.8e-06 28.0 0.0 1.3e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EGG41248.1 - 0.081 12.4 0.3 1 8.8 0.0 2.3 2 1 1 3 3 3 0 short chain dehydrogenase Glycos_transf_1 PF00534.20 EGG41249.1 - 3.9e-34 117.7 0.0 6.4e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG41249.1 - 8.2e-27 94.3 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG41249.1 - 2.5e-18 66.7 0.0 9.9e-18 64.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EGG41249.1 - 3.2e-11 43.5 0.0 6.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGG41249.1 - 8.9e-07 29.5 0.0 0.04 14.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EGG41249.1 - 8.3e-05 22.4 0.0 0.0006 19.6 0.0 1.9 1 1 1 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 EGG41249.1 - 0.0006 19.9 1.2 0.0089 16.1 1.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like PS_pyruv_trans PF04230.13 EGG41249.1 - 0.015 15.2 0.4 0.061 13.2 0.4 1.9 1 1 0 1 1 1 0 Polysaccharide pyruvyl transferase Peptidase_S51 PF03575.17 EGG41249.1 - 0.044 13.4 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S51 Radical_SAM PF04055.21 EGG41250.1 - 3.3e-15 56.9 0.2 3.3e-15 56.9 0.2 2.5 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 EGG41250.1 - 1.1e-06 29.0 0.0 3.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGG41250.1 - 1.7e-06 28.1 0.0 1.7e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain TrmB PF01978.19 EGG41251.1 - 4.3e-21 74.6 0.0 1.4e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 EGG41251.1 - 1e-07 31.4 0.0 1.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_IclR PF09339.10 EGG41251.1 - 3.8e-05 23.4 0.0 0.0002 21.1 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.22 EGG41251.1 - 0.0012 18.7 0.0 0.0042 17.0 0.0 1.9 1 1 1 2 2 2 1 MarR family HTH_24 PF13412.6 EGG41251.1 - 0.0063 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.16 EGG41251.1 - 0.0067 16.8 0.1 0.042 14.2 0.0 2.1 2 0 0 2 2 2 1 Penicillinase repressor HTH_27 PF13463.6 EGG41251.1 - 0.0082 16.6 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 EGG41251.1 - 0.056 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator PLDc_2 PF13091.6 EGG41251.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 PLD-like domain PadR PF03551.14 EGG41251.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MarR_2 PF12802.7 EGG41251.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Fe_dep_repr_C PF02742.15 EGG41252.1 - 3.5e-18 65.5 0.2 6.5e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 EGG41252.1 - 4.4e-15 55.6 0.2 7e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EGG41252.1 - 2.1e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EGG41252.1 - 5.9e-05 23.3 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 EGG41252.1 - 0.00015 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EGG41252.1 - 0.00016 22.1 0.0 0.00028 21.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EGG41252.1 - 0.0011 18.7 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EGG41252.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_45 PF14947.6 EGG41252.1 - 0.0012 18.7 0.2 0.0019 18.2 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_5 PF01022.20 EGG41252.1 - 0.0017 18.2 0.4 0.004 17.0 0.0 1.8 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_1 PF00126.27 EGG41252.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_37 PF13744.6 EGG41252.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Penicillinase_R PF03965.16 EGG41252.1 - 0.09 13.1 0.5 0.14 12.6 0.5 1.4 1 1 0 1 1 1 0 Penicillinase repressor NLPC_P60 PF00877.19 EGG41252.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 2 0 0 2 2 2 0 NlpC/P60 family HTH_29 PF13551.6 EGG41252.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix IF2_N PF04760.15 EGG41252.1 - 0.11 12.3 0.4 0.35 10.7 0.2 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_6 PF01418.17 EGG41252.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_11 PF08279.12 EGG41252.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 HTH domain TFIIE_beta PF02186.15 EGG41252.1 - 0.15 12.4 0.2 0.34 11.2 0.2 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain HTH_IclR PF09339.10 EGG41252.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain zf-RRN7 PF11781.8 EGG41253.1 - 0.00095 18.8 2.5 0.0022 17.7 2.5 1.6 1 1 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 UPF0047 PF01894.17 EGG41254.1 - 1.3e-36 125.2 0.0 1.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 eRF1_1 PF03463.15 EGG41257.1 - 3.1e-19 69.3 2.1 3.5e-19 69.1 0.2 1.9 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 EGG41257.1 - 3.4e-10 40.4 0.7 5.1e-09 36.6 0.3 2.6 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 EGG41257.1 - 1.3e-05 25.5 0.5 4.8e-05 23.7 0.2 2.2 1 1 1 2 2 2 1 eRF1 domain 2 Ribosomal_L7Ae PF01248.26 EGG41257.1 - 0.0093 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family baeRF_family7 PF18849.1 EGG41257.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 CutA1 PF03091.15 EGG41258.1 - 1.7e-31 108.0 3.8 1.8e-31 107.9 3.8 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Peptidase_M50 PF02163.22 EGG41259.1 - 8.3e-18 64.6 5.3 1e-16 61.0 2.0 2.5 2 1 0 2 2 2 1 Peptidase family M50 PDZ_2 PF13180.6 EGG41259.1 - 6.6e-09 36.0 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EGG41259.1 - 8.2e-08 32.0 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGG41259.1 - 0.00083 19.7 0.1 0.0018 18.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain ATP_bind_3 PF01171.20 EGG41260.1 - 6.3e-21 74.9 0.0 9.4e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 EGG41260.1 - 1.6e-05 23.9 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 EGG41260.1 - 0.0022 18.1 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Focal_AT PF03623.13 EGG41263.1 - 0.024 14.6 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Focal adhesion targeting region Acylphosphatase PF00708.18 EGG41264.1 - 1.7e-25 89.2 0.7 1.9e-25 89.1 0.7 1.0 1 0 0 1 1 1 1 Acylphosphatase Ribosomal_L2_C PF03947.18 EGG41265.1 - 7.9e-35 119.8 2.8 1.3e-34 119.1 2.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGG41265.1 - 9.5e-09 35.1 0.0 3.1e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain AAA PF00004.29 EGG41266.1 - 3.6e-100 331.6 0.0 6.7e-50 168.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 EGG41266.1 - 3.9e-30 103.9 0.2 1.5e-29 102.0 0.2 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 EGG41266.1 - 5.6e-23 80.5 0.9 5.3e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGG41266.1 - 8.2e-16 58.8 0.2 6.4e-06 26.7 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 EGG41266.1 - 1.8e-15 57.4 0.0 5.2e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGG41266.1 - 1.9e-14 53.7 0.0 8e-09 35.4 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGG41266.1 - 2.6e-11 43.4 0.5 0.00017 20.9 0.0 3.1 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_22 PF13401.6 EGG41266.1 - 8.4e-11 42.3 0.5 0.0021 18.3 0.1 3.9 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EGG41266.1 - 1.9e-10 40.8 0.9 0.00049 20.1 0.2 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGG41266.1 - 6.1e-10 39.4 0.0 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGG41266.1 - 1.2e-08 35.0 0.0 0.0013 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EGG41266.1 - 1.4e-08 34.3 0.1 3.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 EGG41266.1 - 7.2e-08 32.4 0.0 0.0072 16.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGG41266.1 - 1.1e-07 31.8 0.1 0.037 13.7 0.0 3.3 3 1 0 3 3 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EGG41266.1 - 1.4e-06 28.7 0.0 0.034 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 EGG41266.1 - 2.8e-06 27.3 0.1 0.077 13.0 0.1 2.7 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EGG41266.1 - 2.9e-06 27.3 0.0 0.0063 16.4 0.0 2.7 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_7 PF12775.7 EGG41266.1 - 3.3e-06 26.7 0.0 0.04 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EGG41266.1 - 3.4e-06 27.4 0.0 0.027 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGG41266.1 - 6e-06 25.8 0.7 0.038 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGG41266.1 - 9.3e-06 26.2 0.1 0.068 13.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EGG41266.1 - 1.4e-05 24.9 0.0 0.057 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EGG41266.1 - 2e-05 24.0 4.1 0.12 11.7 0.0 3.8 4 1 0 5 5 3 2 KaiC PhoH PF02562.16 EGG41266.1 - 2.5e-05 23.8 0.2 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ATPase_2 PF01637.18 EGG41266.1 - 4.6e-05 23.5 0.0 0.029 14.3 0.0 3.4 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGG41266.1 - 4.6e-05 24.0 0.0 0.41 11.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.12 EGG41266.1 - 5.6e-05 23.1 0.3 0.71 9.8 0.2 3.4 3 1 1 4 4 3 2 NACHT domain Zeta_toxin PF06414.12 EGG41266.1 - 6.1e-05 22.4 0.9 0.093 12.0 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 EGG41266.1 - 6.5e-05 22.6 2.5 1.1 8.8 0.0 4.0 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EGG41266.1 - 0.00013 21.3 0.0 0.3 10.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 EGG41266.1 - 0.00013 21.2 0.0 0.077 12.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 EGG41266.1 - 0.00061 19.7 0.0 0.51 10.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGG41266.1 - 0.00062 19.5 0.4 1.6 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Cytidylate_kin PF02224.18 EGG41266.1 - 0.00078 19.2 0.1 0.68 9.6 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase DUF2075 PF09848.9 EGG41266.1 - 0.00084 18.7 0.0 0.32 10.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EGG41266.1 - 0.0012 18.0 0.0 0.29 10.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EGG41266.1 - 0.0033 17.5 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 EGG41266.1 - 0.0035 17.2 0.1 0.9 9.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain TniB PF05621.11 EGG41266.1 - 0.0088 15.5 0.0 3.2 7.1 0.0 2.8 2 0 0 2 2 2 1 Bacterial TniB protein CPT PF07931.12 EGG41266.1 - 0.0091 15.9 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 EGG41266.1 - 0.011 15.4 0.2 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.15 EGG41266.1 - 0.016 15.2 0.0 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Guanylate_kin PF00625.21 EGG41266.1 - 0.017 14.8 0.1 12 5.5 0.0 3.5 2 1 1 3 3 3 0 Guanylate kinase NTPase_1 PF03266.15 EGG41266.1 - 0.021 14.7 2.8 8.5 6.3 0.0 3.9 3 1 1 4 4 4 0 NTPase AAA_17 PF13207.6 EGG41266.1 - 0.034 14.6 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGG41266.1 - 0.035 13.8 0.0 9.6 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AFG1_ATPase PF03969.16 EGG41266.1 - 0.038 12.9 0.0 6.7 5.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_19 PF13245.6 EGG41266.1 - 0.04 14.2 2.1 3.9 7.8 0.1 3.2 3 1 0 4 4 2 0 AAA domain PduV-EutP PF10662.9 EGG41266.1 - 0.047 13.4 0.0 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 EGG41266.1 - 0.055 12.5 0.0 7.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EGG41266.1 - 0.078 12.7 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.10 EGG41266.1 - 0.08 13.0 0.9 16 5.6 0.1 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PIF1 PF05970.14 EGG41266.1 - 0.093 11.9 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Torsin PF06309.11 EGG41266.1 - 0.19 11.8 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Torsin Asparaginase PF00710.20 EGG41267.1 - 2e-53 180.8 0.1 3.2e-53 180.1 0.1 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGG41267.1 - 2.5e-30 105.0 0.0 4.5e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain GatD_N PF18195.1 EGG41267.1 - 4.9e-18 64.2 1.5 4.9e-18 64.2 1.5 2.1 2 0 0 2 2 2 1 GatD N-terminal domain zf-ribbon_3 PF13248.6 EGG41268.1 - 0.064 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain NT5C PF06941.12 EGG41269.1 - 4e-13 49.6 1.3 4.9e-13 49.3 1.3 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DnaJ_C PF01556.18 EGG41270.1 - 1.1e-37 129.4 0.4 1.7e-37 128.8 0.4 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG41270.1 - 5.9e-27 93.6 0.7 9.9e-27 92.9 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG41270.1 - 4.7e-13 49.3 20.1 8.7e-13 48.4 20.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGG41270.1 - 2.8 8.0 20.4 7 6.7 5.9 2.9 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein VWA_N2 PF16164.5 EGG41270.1 - 5.7 7.2 11.5 0.77 9.9 5.1 2.2 1 1 1 2 2 2 0 VWA N-terminal HSP70 PF00012.20 EGG41271.1 - 1.8e-216 720.0 17.5 3.2e-196 653.1 13.4 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EGG41271.1 - 4.4e-17 61.9 6.6 4.4e-17 61.9 6.6 2.1 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGG41271.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 EGG41271.1 - 0.018 14.8 0.0 0.11 12.2 0.0 2.5 1 0 0 1 1 1 0 RACo middle region DUF1885 PF08968.10 EGG41271.1 - 0.16 12.1 1.7 0.29 11.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) TetR_C_19 PF17924.1 EGG41271.1 - 0.37 11.4 9.4 0.15 12.6 5.9 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1664 PF07889.12 EGG41271.1 - 7.1 6.7 7.5 0.7 9.9 0.9 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) GrpE PF01025.19 EGG41272.1 - 3.7e-37 127.6 6.2 4.6e-37 127.2 6.2 1.1 1 0 0 1 1 1 1 GrpE FOXP-CC PF16159.5 EGG41272.1 - 0.092 13.4 3.2 0.14 12.8 2.4 1.7 1 1 0 1 1 1 0 FOXP coiled-coil domain BAR PF03114.18 EGG41272.1 - 0.2 11.3 7.1 0.27 10.8 7.1 1.1 1 0 0 1 1 1 0 BAR domain DUF334 PF03904.13 EGG41272.1 - 0.41 10.1 10.2 0.62 9.6 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF3783 PF12646.7 EGG41273.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) DUF354 PF04007.12 EGG41274.1 - 7.1e-49 166.7 4.7 7.8e-49 166.5 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) LpxB PF02684.15 EGG41274.1 - 0.0011 17.9 0.3 0.002 17.0 0.3 1.4 1 1 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.19 EGG41274.1 - 0.017 14.0 0.3 0.027 13.3 0.3 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase AAA_12 PF13087.6 EGG41274.1 - 0.026 14.1 0.8 0.053 13.1 0.8 1.5 1 0 0 1 1 1 0 AAA domain UDPG_MGDP_dh_N PF03721.14 EGG41275.1 - 5.7e-07 29.3 0.1 0.02 14.5 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EGG41275.1 - 5e-06 26.8 0.0 9.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh PF00984.19 EGG41275.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain OKR_DC_1 PF01276.20 EGG41275.1 - 0.038 12.7 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain NAD_binding_2 PF03446.15 EGG41275.1 - 0.042 14.0 0.0 0.33 11.1 0.0 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 EGG41275.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGG41275.1 - 0.18 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ABC2_membrane PF01061.24 EGG41276.1 - 1.1e-20 74.0 22.2 1.1e-20 74.0 22.2 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EGG41276.1 - 6.9e-14 51.7 36.9 1.5e-13 50.6 26.4 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EGG41276.1 - 0.013 14.8 20.2 0.022 14.1 20.2 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Phage_holin_4_1 PF05105.12 EGG41276.1 - 0.21 11.8 7.5 0.077 13.2 3.6 2.3 1 1 1 2 2 2 0 Bacteriophage holin family ABC2_membrane_4 PF12730.7 EGG41276.1 - 0.74 9.7 18.7 0.047 13.6 12.0 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 EGG41277.1 - 4.7e-29 101.6 0.0 8.1e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG41277.1 - 2.3e-13 50.6 0.1 8.2e-07 29.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EGG41277.1 - 4.5e-06 27.3 1.7 1.6e-05 25.5 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EGG41277.1 - 7.4e-06 25.9 0.1 0.00054 19.8 0.1 3.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGG41277.1 - 0.006 16.3 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGG41277.1 - 0.045 13.1 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EGG41277.1 - 0.076 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 EGG41277.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EGG41277.1 - 0.14 11.6 2.2 9.8 5.5 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGG41277.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGG41277.1 - 0.21 12.1 9.6 1.5 9.3 9.6 2.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGG41277.1 - 0.25 11.5 1.7 9 6.4 0.2 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 EGG41277.1 - 1.3 9.1 6.5 7.3 6.6 0.3 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain tRNA_anti-codon PF01336.25 EGG41278.1 - 1.1e-11 44.5 0.8 0.0045 16.9 0.0 4.2 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EGG41278.1 - 6.2e-08 32.6 0.0 0.00011 22.0 0.0 2.5 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 POT1PC PF16686.5 EGG41278.1 - 0.001 18.9 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 2 ssDNA-binding domain of telomere protection protein DEAD_assoc PF08494.11 EGG41279.1 - 0.01 15.7 0.0 0.024 14.4 0.0 1.6 2 0 0 2 2 2 0 DEAD/H associated HypA PF01155.19 EGG41279.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytadhesin_P30 PF07271.11 EGG41279.1 - 0.065 12.8 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Zn-ribbon_8 PF09723.10 EGG41279.1 - 0.12 12.5 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain PriA_CRR PF18319.1 EGG41279.1 - 0.25 11.3 1.2 16 5.6 0.3 2.4 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain DEAD PF00270.29 EGG41280.1 - 1.3e-34 119.5 0.2 2.2e-34 118.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG41280.1 - 3.7e-20 72.3 0.2 1.3e-17 64.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD_assoc PF08494.11 EGG41280.1 - 2.2e-14 53.7 0.0 4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/H associated ResIII PF04851.15 EGG41280.1 - 6.7e-12 45.7 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGG41280.1 - 0.0019 17.0 0.0 0.003 16.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.6 EGG41280.1 - 0.004 17.5 0.0 0.0093 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 EGG41280.1 - 0.0061 16.2 0.1 0.057 13.1 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EGG41280.1 - 0.067 13.5 2.4 3.4 7.9 0.6 2.9 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 EGG41280.1 - 0.15 11.6 0.1 0.34 10.4 0.1 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Secretin_N_2 PF07655.13 EGG41280.1 - 0.46 11.1 4.2 1 10.0 4.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Rad51 PF08423.11 EGG41282.1 - 1.3e-28 99.9 0.6 1.6e-28 99.7 0.6 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGG41282.1 - 9.8e-11 41.6 0.2 1.3e-10 41.2 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EGG41282.1 - 9e-08 31.7 5.9 1.5e-06 27.8 5.4 2.3 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 EGG41282.1 - 9.9e-05 22.1 0.4 0.00019 21.2 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGG41282.1 - 0.00046 19.8 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG41282.1 - 0.0022 18.5 1.3 0.003 18.1 1.2 1.4 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 EGG41282.1 - 0.0077 16.2 4.7 0.015 15.2 4.7 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EGG41282.1 - 0.012 15.3 0.2 0.038 13.7 0.1 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 EGG41282.1 - 0.013 15.9 0.6 0.025 15.0 0.6 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EGG41282.1 - 0.05 12.5 0.1 0.092 11.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EGG41282.1 - 0.19 12.1 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 EGG41282.1 - 0.26 11.3 1.1 0.52 10.4 1.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain S-AdoMet_synt_C PF02773.16 EGG41283.1 - 2.8e-69 231.4 0.1 2.2e-68 228.5 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGG41283.1 - 1.9e-50 170.2 0.4 6.4e-49 165.2 0.0 2.3 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGG41283.1 - 9.5e-41 138.5 2.5 3.3e-40 136.8 0.2 2.6 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EGG41283.1 - 0.0045 15.8 3.1 0.66 8.7 0.2 2.3 1 1 1 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) Mt_ATP-synt_B PF05405.14 EGG41283.1 - 0.13 11.9 0.6 0.36 10.4 0.3 1.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Epimerase PF01370.21 EGG41284.1 - 8.5e-14 51.6 0.1 8.6e-13 48.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG41284.1 - 1.3e-13 51.2 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGG41284.1 - 1.2e-08 34.3 1.5 3.6e-06 26.2 0.7 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG41284.1 - 1.7e-05 24.1 0.0 0.14 11.2 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain PAC2 PF09754.9 EGG41284.1 - 0.00029 20.9 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 PAC2 family NAD_binding_4 PF07993.12 EGG41284.1 - 0.00041 19.6 0.2 0.12 11.5 0.0 2.9 1 1 1 2 2 2 1 Male sterility protein Shikimate_DH PF01488.20 EGG41284.1 - 0.00055 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EGG41284.1 - 0.024 14.0 0.1 0.074 12.4 0.1 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Thump_like PF18096.1 EGG41284.1 - 0.03 14.2 0.2 0.12 12.3 0.2 2.1 1 0 0 1 1 1 0 THUMP domain-like DUF296 PF03479.15 EGG41284.1 - 0.044 14.2 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain DDE_Tnp_1_3 PF13612.6 EGG41284.1 - 0.046 13.7 1.8 0.15 12.1 0.2 2.6 2 1 1 3 3 3 0 Transposase DDE domain DUF1863 PF08937.11 EGG41284.1 - 0.051 13.9 1.4 0.082 13.2 0.5 1.7 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Semialdhyde_dh PF01118.24 EGG41284.1 - 0.085 13.3 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGG41284.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CbiD PF01888.17 EGG41285.1 - 5.4e-92 307.6 1.5 6.8e-92 307.3 1.5 1.1 1 0 0 1 1 1 1 CbiD DUF3042 PF11240.8 EGG41285.1 - 0.099 12.7 4.3 0.2 11.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) CbiG_N PF11760.8 EGG41286.1 - 1.8e-33 114.4 0.3 2.8e-33 113.8 0.3 1.3 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_C PF01890.16 EGG41286.1 - 3.7e-25 88.8 0.1 8e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Cobalamin synthesis G C-terminus CbiG_mid PF11761.8 EGG41286.1 - 2e-14 53.5 0.0 5.7e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Cobalamin biosynthesis central region SpoU_sub_bind PF08032.12 EGG41286.1 - 0.085 13.2 0.0 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding CbiX PF01903.17 EGG41287.1 - 2.6e-37 127.4 0.0 2.7e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 EGG41287.1 - 1.6e-09 37.5 2.0 1.9e-09 37.2 2.0 1.1 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 EGG41287.1 - 1.1e-07 31.3 0.1 0.00054 19.1 0.0 2.0 1 1 1 2 2 2 2 Ferrochelatase CbiC PF02570.15 EGG41288.1 - 5.4e-73 244.8 0.7 6.1e-73 244.7 0.7 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase GATase_3 PF07685.14 EGG41289.1 - 4.8e-40 137.3 0.1 8e-40 136.5 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 EGG41289.1 - 2.9e-19 69.4 0.0 7.1e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 EGG41289.1 - 1.3e-13 51.3 0.3 3.5e-06 27.0 0.0 2.8 3 1 1 4 4 4 2 AAA domain SNO PF01174.19 EGG41289.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family CTP_synth_N PF06418.14 EGG41289.1 - 0.0064 15.8 0.0 0.0064 15.8 0.0 2.0 3 0 0 3 3 3 1 CTP synthase N-terminus DUF1611 PF07755.11 EGG41289.1 - 0.036 13.3 0.1 0.094 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain DUF3217 PF11506.8 EGG41289.1 - 0.087 12.8 1.6 4.8 7.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3217) CobA_CobO_BtuR PF02572.15 EGG41290.1 - 1.1e-61 208.1 0.2 1.2e-61 207.9 0.2 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_14 PF13173.6 EGG41290.1 - 0.0017 18.4 0.4 0.0033 17.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGG41290.1 - 1.1 8.8 2.3 6.4 6.3 2.1 2.2 1 1 1 2 2 2 0 AAA domain EIF_2_alpha PF07541.12 EGG41291.1 - 9.1e-19 67.7 0.6 9.1e-19 67.7 0.6 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGG41291.1 - 2.1e-12 47.2 0.2 1.1e-11 45.0 0.1 2.2 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.9 EGG41291.1 - 0.015 15.9 0.3 0.053 14.1 0.1 2.1 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 Nop10p PF04135.12 EGG41292.1 - 4.1e-23 81.2 3.5 4.2e-23 81.1 3.5 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family RecR PF02132.15 EGG41292.1 - 0.0014 18.1 1.8 0.0018 17.8 1.8 1.2 1 0 0 1 1 1 1 RecR protein PolC_DP2 PF03833.13 EGG41292.1 - 0.0074 14.2 0.2 0.0074 14.2 0.2 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 Prok-RING_4 PF14447.6 EGG41292.1 - 0.044 13.7 1.8 0.054 13.4 1.8 1.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 STT3 PF02516.14 EGG41293.1 - 1.3e-37 129.8 31.3 2.3e-37 129.1 31.3 1.5 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.9 EGG41293.1 - 0.0018 16.6 0.5 0.0018 16.6 0.5 2.4 2 0 0 2 2 2 1 Q-cell neuroblast polarisation PBP PF01161.20 EGG41294.1 - 2.3e-38 131.5 0.0 2.7e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PIN_9 PF18477.1 EGG41295.1 - 3.3e-10 40.3 0.0 3.9e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 PIN like domain Fcf1 PF04900.12 EGG41295.1 - 0.00022 21.5 0.0 0.00027 21.3 0.0 1.1 1 0 0 1 1 1 1 Fcf1 BRCT PF00533.26 EGG41295.1 - 0.0064 16.8 0.4 0.02 15.2 0.1 1.9 1 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain partial_CstF PF15861.5 EGG41295.1 - 0.12 12.1 2.1 3.6 7.4 0.1 2.2 1 1 1 2 2 2 0 Partial cleavage stimulation factor domain GTP_EFTU PF00009.27 EGG41296.1 - 2.1e-30 105.8 0.1 6.5e-30 104.1 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 EGG41296.1 - 6.4e-26 90.4 0.2 5.6e-25 87.4 0.1 2.5 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 EGG41296.1 - 1.8e-06 28.2 0.5 5.5e-06 26.7 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG41296.1 - 2.5e-05 24.3 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG41296.1 - 0.00025 21.0 0.4 0.008 16.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGG41296.1 - 0.0077 16.2 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EGG41296.1 - 0.032 13.8 0.4 2 7.9 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B NOB1_Zn_bind PF08772.11 EGG41296.1 - 0.059 13.5 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like ProQ_C PF17516.2 EGG41296.1 - 0.087 12.3 0.0 0.29 10.6 0.0 1.9 1 0 0 1 1 1 0 ProQ C-terminal domain ILEI PF15711.5 EGG41296.1 - 0.12 12.9 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Interleukin-like EMT inducer HypA PF01155.19 EGG41296.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S6e PF01092.19 EGG41297.1 - 5.8e-25 87.7 0.1 6.8e-25 87.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e zinc_ribbon_2 PF13240.6 EGG41298.1 - 0.0002 21.0 10.1 0.009 15.7 1.3 2.3 1 1 2 3 3 3 3 zinc-ribbon domain zf-C4_Topoisom PF01396.19 EGG41298.1 - 0.005 16.6 7.5 0.4 10.5 0.5 2.3 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.6 EGG41298.1 - 0.0062 15.9 10.3 0.064 12.7 1.8 2.2 1 1 1 2 2 2 2 zinc-ribbon domain RPA_interact_C PF14768.6 EGG41298.1 - 0.0081 16.7 4.9 0.0086 16.6 4.9 1.0 1 0 0 1 1 1 1 Replication protein A interacting C-terminal zf-ACC PF17848.1 EGG41298.1 - 0.01 15.9 2.9 1 9.5 0.4 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain FYDLN_acid PF09538.10 EGG41298.1 - 0.011 16.5 2.9 0.012 16.3 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc-ribbons_6 PF07191.12 EGG41298.1 - 0.013 15.5 7.0 0.023 14.7 6.9 1.5 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 EGG41298.1 - 0.016 15.2 6.9 0.07 13.2 7.2 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-RRPl_C4 PF17026.5 EGG41298.1 - 0.02 15.0 2.4 0.02 15.0 2.4 1.0 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type A2L_zn_ribbon PF08792.10 EGG41298.1 - 0.023 14.4 5.0 0.063 13.0 5.0 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain zf-TFIIB PF13453.6 EGG41298.1 - 0.029 13.7 7.2 0.36 10.2 1.6 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger zf_UBZ PF18439.1 EGG41298.1 - 0.032 13.8 8.2 0.49 10.0 2.0 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 EGG41298.1 - 0.075 12.6 6.3 0.13 11.9 6.3 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding DUF1936 PF09151.10 EGG41298.1 - 0.088 12.7 4.0 4.1 7.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) DUF555 PF04475.12 EGG41298.1 - 0.094 13.0 0.9 0.43 10.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF555) OrfB_Zn_ribbon PF07282.11 EGG41298.1 - 0.098 12.6 5.2 0.12 12.4 5.2 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Mss51 PF13824.6 EGG41298.1 - 0.1 12.7 6.4 0.13 12.4 6.4 1.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ogr_Delta PF04606.12 EGG41298.1 - 0.14 12.2 4.9 4.5 7.3 0.7 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_Tnp_IS91 PF14319.6 EGG41298.1 - 0.16 12.0 5.9 0.17 11.9 5.9 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain Ribosomal_S27e PF01667.17 EGG41298.1 - 0.17 11.6 5.2 0.27 11.0 5.2 1.4 1 1 0 1 1 1 0 Ribosomal protein S27 HypA PF01155.19 EGG41298.1 - 0.19 11.8 5.5 0.22 11.6 5.5 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_10 PF18414.1 EGG41298.1 - 0.19 11.3 8.5 1.1 8.9 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger zf-FPG_IleRS PF06827.14 EGG41298.1 - 0.24 11.3 8.1 1.5 8.8 8.2 2.0 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS zf-NADH-PPase PF09297.11 EGG41298.1 - 0.26 11.0 6.9 0.35 10.6 2.5 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.11 EGG41298.1 - 0.28 11.4 6.6 0.8 9.9 6.6 1.7 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Cys_rich_KTR PF14205.6 EGG41298.1 - 0.29 10.9 8.2 9.4 6.1 8.2 2.1 1 1 0 1 1 1 0 Cysteine-rich KTR zf-ISL3 PF14690.6 EGG41298.1 - 0.53 11.0 7.7 2.8 8.7 0.5 2.2 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Mu-like_Com PF10122.9 EGG41298.1 - 0.75 9.3 9.4 0.48 9.9 1.3 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com Zn_ribbon_recom PF13408.6 EGG41298.1 - 0.75 10.4 6.1 64 4.2 6.1 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain RNA_POL_M_15KD PF02150.16 EGG41298.1 - 0.81 9.6 9.8 0.21 11.5 1.5 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.9 EGG41298.1 - 1.1 9.4 11.8 32 4.7 11.9 2.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-HIT PF04438.16 EGG41298.1 - 1.2 9.1 9.1 3 7.8 0.6 2.3 2 1 0 2 2 2 0 HIT zinc finger DUF3797 PF12677.7 EGG41298.1 - 2.5 8.1 8.1 2.2 8.2 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Rep_fac-A_C PF08646.10 EGG41298.1 - 2.5 7.8 6.6 2.7 7.7 6.6 1.0 1 0 0 1 1 1 0 Replication factor-A C terminal domain IBR PF01485.21 EGG41299.1 - 0.0021 18.3 0.9 0.0035 17.5 0.9 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 EGG41299.1 - 0.0021 18.0 2.2 0.012 15.5 2.2 2.0 1 1 0 1 1 1 1 zinc-ribbon domain CpXC PF14353.6 EGG41299.1 - 0.0067 16.5 2.3 0.044 13.8 0.0 2.0 1 1 1 2 2 2 1 CpXC protein OrfB_Zn_ribbon PF07282.11 EGG41299.1 - 0.021 14.8 0.2 0.026 14.4 0.2 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YacG PF03884.14 EGG41299.1 - 0.029 14.1 0.2 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf_C2H2_10 PF18414.1 EGG41299.1 - 0.057 13.0 1.9 1.4 8.5 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-Di19 PF05605.12 EGG41299.1 - 0.062 13.6 3.3 0.25 11.6 0.3 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_S27e PF01667.17 EGG41299.1 - 0.087 12.5 2.3 0.2 11.4 2.4 1.6 1 1 0 1 1 1 0 Ribosomal protein S27 zf-BED PF02892.15 EGG41299.1 - 0.1 12.6 1.6 0.54 10.3 0.1 2.1 1 1 1 2 2 2 0 BED zinc finger HypA PF01155.19 EGG41299.1 - 0.11 12.6 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_5 PF13909.6 EGG41299.1 - 0.15 11.9 0.7 0.15 11.9 0.7 1.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 EGG41299.1 - 0.23 11.9 3.3 6.7 7.3 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.6 EGG41299.1 - 0.27 10.7 7.4 4.8 6.7 7.4 2.2 1 1 0 1 1 1 0 zinc-ribbon domain DUF2197 PF09963.9 EGG41299.1 - 0.37 11.1 3.0 3.3 8.0 2.8 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) TPR_1 PF00515.28 EGG41300.1 - 2.9e-14 52.2 16.0 2.4e-08 33.5 1.4 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG41300.1 - 8.5e-12 44.2 10.8 1.7e-06 27.7 0.5 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG41300.1 - 4.2e-11 42.4 13.1 0.00083 19.6 1.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG41300.1 - 7.1e-09 35.2 14.7 2.4e-05 24.2 0.9 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG41300.1 - 2.6e-07 30.2 11.7 0.00013 21.6 0.1 3.9 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.6 EGG41300.1 - 6.9e-06 26.5 0.5 0.085 13.4 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG41300.1 - 1.7e-05 25.0 0.4 0.0068 16.7 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG41300.1 - 2.1e-05 24.9 0.0 0.45 11.5 0.0 3.8 1 1 3 4 4 4 2 Tetratricopeptide repeat Peptidase_C39_2 PF13529.6 EGG41300.1 - 8.4e-05 23.2 0.1 0.00022 21.8 0.1 1.7 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 EGG41300.1 - 0.00039 20.2 0.0 0.0096 15.7 0.0 2.4 2 1 0 2 2 2 1 Peptidase C39 family TPR_16 PF13432.6 EGG41300.1 - 0.00071 20.2 0.0 4.9 7.9 0.0 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG41300.1 - 0.0012 19.4 1.5 3 8.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG41300.1 - 0.0012 18.9 0.0 0.0056 16.8 0.0 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat GATase PF00117.28 EGG41301.1 - 8.7e-20 71.3 0.0 1e-19 71.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG41301.1 - 2.5e-08 34.0 0.0 1e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 EGG41301.1 - 0.018 14.9 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 SNO glutamine amidotransferase family UPF0182 PF03699.13 EGG41302.1 - 3.7e-34 118.0 22.0 4.6e-33 114.4 22.0 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) DNA_primase_S PF01896.19 EGG41303.1 - 7.3e-16 58.7 0.9 2.2e-14 53.9 0.0 2.4 1 1 1 2 2 2 1 DNA primase small subunit PolC_DP2 PF03833.13 EGG41303.1 - 0.036 11.9 4.9 0.049 11.5 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Rhodanese_C PF12368.8 EGG41303.1 - 0.35 11.3 8.1 0.91 9.9 8.1 1.6 1 0 0 1 1 1 0 Rhodanase C-terminal DUF3624 PF12292.8 EGG41303.1 - 0.52 10.7 2.2 1.1 9.7 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) HypA PF01155.19 EGG41303.1 - 5.8 7.0 10.1 1.4 9.0 6.2 1.9 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_primase_lrg PF04104.14 EGG41304.1 - 2.9e-25 89.2 0.0 8.9e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Med5 PF08689.10 EGG41304.1 - 0.0025 15.7 0.1 0.0031 15.4 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 Aminotran_3 PF00202.21 EGG41304.1 - 0.19 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III AP_endonuc_2 PF01261.24 EGG41305.1 - 1.7e-35 122.3 0.0 9.2e-35 120.0 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF3445 PF11927.8 EGG41305.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) HGTP_anticodon PF03129.20 EGG41306.1 - 1.1e-16 60.8 0.2 2.7e-16 59.5 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGG41306.1 - 8.2e-13 48.7 0.7 1.1e-11 45.1 0.7 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zinc_ribbon_15 PF17032.5 EGG41306.1 - 0.089 13.6 1.5 0.33 11.7 1.1 2.1 1 1 1 2 2 2 0 zinc-ribbon family zf-TFIIB PF13453.6 EGG41306.1 - 0.13 11.6 1.0 6.3 6.2 0.1 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-RRPl_C4 PF17026.5 EGG41306.1 - 0.16 12.1 1.2 0.44 10.7 0.2 2.4 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_4 PF13717.6 EGG41306.1 - 0.6 10.1 4.3 9.7 6.2 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 EGG41306.1 - 0.68 9.7 6.8 1.8 8.4 0.9 3.0 3 0 0 3 3 3 0 zinc-ribbon domain HemolysinCabind PF00353.19 EGG41307.1 - 1.6e-38 130.3 108.7 1.6e-10 40.7 18.5 4.1 1 1 4 5 5 5 5 RTX calcium-binding nonapeptide repeat (4 copies) Collagen PF01391.18 EGG41307.1 - 7.2 6.4 22.1 1.2e+03 -0.7 22.1 3.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Fibrillarin PF01269.17 EGG41308.1 - 4.7e-89 297.4 0.4 5.1e-89 297.3 0.4 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGG41308.1 - 2.8e-05 23.9 0.0 3.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGG41308.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4651 PF15513.6 EGG41308.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) RNase_HII PF01351.18 EGG41309.1 - 1.3e-20 74.1 0.1 1.5e-20 73.9 0.1 1.0 1 0 0 1 1 1 1 Ribonuclease HII RNase_HII PF01351.18 EGG41310.1 - 2e-16 60.4 0.4 2.2e-16 60.3 0.4 1.0 1 0 0 1 1 1 1 Ribonuclease HII TRM PF02005.16 EGG41311.1 - 5.1e-83 279.3 0.0 5.8e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EGG41311.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 EGG41311.1 - 0.012 15.4 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Rrf2 PF02082.20 EGG41311.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 EGG41311.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 EGG41311.1 - 0.048 13.2 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Mga PF08280.11 EGG41311.1 - 0.1 12.7 0.0 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain MTS PF05175.14 EGG41311.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGG41311.1 - 0.18 12.5 0.0 0.38 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EGG41312.1 - 1.1e-48 165.7 0.0 1.2e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EGG41312.1 - 6.7e-05 22.7 0.0 8.5e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG41312.1 - 7.1e-05 23.4 0.1 0.00025 21.7 0.1 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EGG41312.1 - 0.0043 16.7 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EGG41312.1 - 0.0086 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGG41312.1 - 0.0087 15.9 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RNA_pol_Rpc34 PF05158.12 EGG41313.1 - 0.00012 21.6 0.1 0.00021 20.8 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR PF01047.22 EGG41313.1 - 0.012 15.6 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 MarR family z-alpha PF02295.17 EGG41313.1 - 0.049 13.7 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain TIG PF01833.24 EGG41315.1 - 0.077 13.1 3.2 0.39 10.8 3.2 2.3 1 1 0 1 1 1 0 IPT/TIG domain Neprosin PF03080.15 EGG41315.1 - 0.083 12.2 0.9 0.1 12.0 0.9 1.0 1 0 0 1 1 1 0 Neprosin AAA_15 PF13175.6 EGG41316.1 - 3.6e-25 89.5 3.0 3.6e-25 89.5 3.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGG41316.1 - 8e-13 48.9 13.4 1.5e-11 44.7 6.0 3.6 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 EGG41316.1 - 0.0019 17.5 0.1 1.8 7.8 0.0 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF2813) ABC_tran PF00005.27 EGG41316.1 - 0.0027 18.2 1.3 0.0079 16.7 0.1 2.4 2 1 0 2 2 2 1 ABC transporter AAA_27 PF13514.6 EGG41316.1 - 0.0058 16.2 0.1 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGG41316.1 - 0.0058 16.3 0.1 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain Glyco_hydro_42C PF08533.10 EGG41316.1 - 0.14 11.9 0.1 0.82 9.4 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain SMC_N PF02463.19 EGG41316.1 - 0.16 11.4 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGG41316.1 - 3.7 8.0 23.9 0.17 12.4 13.6 3.5 2 1 0 2 2 2 0 AAA domain MG2 PF01835.19 EGG41317.1 - 1.6e-20 73.4 0.7 4.6e-05 23.8 0.0 5.6 6 0 0 6 6 6 4 MG2 domain FlgD_ig PF13860.6 EGG41317.1 - 1.4e-09 37.7 8.6 0.07 13.0 0.7 6.3 5 2 1 6 6 6 3 FlgD Ig-like domain Big_6 PF17936.1 EGG41317.1 - 7.1e-05 23.0 7.8 0.002 18.3 0.4 4.7 4 2 0 4 4 4 1 Bacterial Ig domain bMG3 PF11974.8 EGG41317.1 - 0.0009 19.2 0.2 1.9 8.6 0.1 4.2 3 1 1 4 4 4 1 Bacterial alpha-2-macroglobulin MG3 domain FixH PF05751.11 EGG41317.1 - 0.00094 19.2 0.1 0.12 12.4 0.0 3.5 3 0 0 3 3 3 1 FixH CarboxypepD_reg PF13620.6 EGG41317.1 - 0.029 14.7 10.6 0.056 13.7 0.6 5.4 6 1 0 6 6 6 0 Carboxypeptidase regulatory-like domain DUF4625 PF15418.6 EGG41317.1 - 0.046 14.0 1.6 11 6.2 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4625) TIG PF01833.24 EGG41317.1 - 0.052 13.6 1.0 0.57 10.3 1.0 2.9 1 1 0 1 1 1 0 IPT/TIG domain Pribosyltran PF00156.27 EGG41318.1 - 2.6e-14 53.0 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG41318.1 - 0.0079 15.7 0.0 0.0098 15.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PNP_UDP_1 PF01048.20 EGG41319.1 - 3.6e-42 144.2 0.0 4e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3215 PF11503.8 EGG41320.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DUF4882 PF16223.5 EGG41320.1 - 0.085 12.1 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) MRF_C2 PF13888.6 EGG41321.1 - 0.01 15.7 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 TrmB PF01978.19 EGG41322.1 - 0.00053 19.8 0.0 0.00085 19.2 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB BaxI_1 PF12811.7 EGG41323.1 - 0.0074 15.9 2.8 0.0075 15.9 2.8 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like VEGFR-2_TMD PF17988.1 EGG41324.1 - 0.14 11.6 2.3 0.29 10.6 2.3 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Shisa PF13908.6 EGG41324.1 - 0.24 11.6 0.0 0.3 11.3 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TP6A_N PF04406.14 EGG41325.1 - 4.6e-15 55.3 0.1 7.6e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.22 EGG41325.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Topo-VIb_trans PF09239.11 EGG41326.1 - 9.2e-55 184.8 0.0 1.4e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 EGG41326.1 - 3.1e-06 27.7 0.0 6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGG41326.1 - 0.00033 20.5 0.0 0.00071 19.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MqsA_antitoxin PF15731.5 EGG41326.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Ribosomal_S13 PF00416.22 EGG41326.1 - 0.17 12.3 0.0 0.93 9.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S13/S18 KH_1 PF00013.29 EGG41327.1 - 8.8e-10 38.3 10.1 8.6e-05 22.3 1.2 2.7 2 1 1 3 3 3 2 KH domain GP57 PF17594.2 EGG41327.1 - 0.0081 15.9 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Phage Tail fiber assembly helper gene product 57 KH_2 PF07650.17 EGG41327.1 - 0.03 14.1 5.6 2.8 7.9 0.2 2.9 2 1 0 2 2 2 0 KH domain DUF4335 PF14233.6 EGG41327.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) RIO1 PF01163.22 EGG41328.1 - 9.3e-52 175.4 0.0 1.2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGG41328.1 - 0.014 15.3 0.0 5.5 6.8 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG41328.1 - 0.019 13.7 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase BBS2_Mid PF14783.6 EGG41328.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Kdo PF06293.14 EGG41328.1 - 0.13 11.6 0.0 2.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF424 PF04242.13 EGG41329.1 - 1.2e-21 76.8 0.4 1.3e-21 76.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) eIF-5_eIF-2B PF01873.17 EGG41330.1 - 5e-26 90.9 0.0 5.6e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Elf1 PF05129.13 EGG41330.1 - 0.045 13.8 0.4 0.072 13.2 0.2 1.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 EGG41330.1 - 0.057 13.8 0.3 0.084 13.3 0.3 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 EGG41330.1 - 0.11 12.0 0.4 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding GATA PF00320.27 EGG41330.1 - 0.18 11.4 2.0 0.18 11.5 0.7 1.7 2 0 0 2 2 2 0 GATA zinc finger zinc_ribbon_2 PF13240.6 EGG41331.1 - 0.0021 17.7 1.5 0.13 12.0 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 EGG41331.1 - 0.0037 17.2 0.8 0.0053 16.8 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 EGG41331.1 - 0.019 15.0 0.7 0.021 14.8 0.7 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 EGG41331.1 - 0.027 15.2 0.8 0.032 15.0 0.8 1.1 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 EGG41331.1 - 0.056 12.9 2.6 0.26 10.7 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 EGG41331.1 - 0.074 13.0 2.2 6.3 6.8 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain GFA PF04828.14 EGG41331.1 - 0.1 13.0 2.3 0.3 11.5 2.3 1.7 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.10 EGG41331.1 - 0.16 12.1 3.3 0.47 10.6 3.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 EGG41331.1 - 0.16 11.9 6.9 0.77 9.7 6.9 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EGG41331.1 - 0.18 12.0 4.2 1.1 9.5 0.1 2.2 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MAT1 PF06391.13 EGG41332.1 - 0.86 9.4 7.4 0.86 9.4 2.6 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF373 PF04123.13 EGG41333.1 - 2.1e-89 300.3 15.2 2.5e-89 300.0 15.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF373) SPC12 PF06645.13 EGG41333.1 - 7 6.8 7.2 0.5 10.5 0.5 2.5 2 1 2 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Prenyltransf PF01255.19 EGG41334.1 - 5.6e-70 235.4 0.0 6.3e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase NUDIX PF00293.28 EGG41335.1 - 8.5e-21 74.4 0.4 1e-20 74.1 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain PhosphMutase PF10143.9 EGG41335.1 - 0.05 13.5 0.2 0.068 13.1 0.2 1.1 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase OMPdecase PF00215.24 EGG41336.1 - 4.7e-26 91.8 0.0 5.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Adenylsucc_synt PF00709.21 EGG41338.1 - 2.8e-83 280.2 0.9 1e-39 136.7 0.0 3.0 1 1 2 3 3 3 3 Adenylosuccinate synthetase Catalase-rel PF06628.12 EGG41339.1 - 0.0098 16.1 0.0 27 5.1 0.0 3.2 3 0 0 3 3 3 2 Catalase-related immune-responsive Annexin PF00191.20 EGG41339.1 - 0.0099 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Annexin Iron_traffic PF04362.14 EGG41340.1 - 4.7e-07 29.4 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking PriX PF18689.1 EGG41340.1 - 0.089 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Primase X zf_C2H2_13 PF18508.1 EGG41340.1 - 1.5 8.5 4.0 4.5 6.9 0.3 2.5 1 1 1 2 2 2 0 Zinc finger domain DUF202 PF02656.15 EGG41342.1 - 5.7 7.5 9.6 14 6.2 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF3185 PF11381.8 EGG41342.1 - 7.6 6.6 9.3 7.3 6.7 0.2 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3185) HTH_45 PF14947.6 EGG41343.1 - 1.9e-11 43.7 0.2 2.5e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 EGG41343.1 - 2.9e-07 30.3 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 EGG41343.1 - 5.7e-05 22.8 0.0 7.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain RP-C PF03428.13 EGG41343.1 - 0.00028 20.6 0.1 0.00033 20.4 0.1 1.1 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF4364 PF14277.6 EGG41343.1 - 0.00033 20.4 0.0 0.00044 20.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4364) MarR PF01047.22 EGG41343.1 - 0.00042 20.2 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EGG41343.1 - 0.00048 20.0 0.0 0.00066 19.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EGG41343.1 - 0.0007 19.1 0.4 0.0014 18.1 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding RQC PF09382.10 EGG41343.1 - 0.0033 17.2 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 RQC domain HTH_27 PF13463.6 EGG41343.1 - 0.0036 17.7 0.0 0.0044 17.5 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Dimerisation2 PF16864.5 EGG41343.1 - 0.004 17.1 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain Linker_histone PF00538.19 EGG41343.1 - 0.006 16.9 0.1 0.014 15.7 0.1 1.7 1 1 0 1 1 1 1 linker histone H1 and H5 family FtsK_gamma PF09397.10 EGG41343.1 - 0.0089 15.8 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Ftsk gamma domain RPA_C PF08784.11 EGG41343.1 - 0.0094 16.6 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 Replication protein A C terminal Mrr_N PF14338.6 EGG41343.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 Mrr N-terminal domain Rrf2 PF02082.20 EGG41343.1 - 0.015 15.6 0.1 0.019 15.3 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 EGG41343.1 - 0.019 14.8 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1495 PF07381.11 EGG41343.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) HTH_36 PF13730.6 EGG41343.1 - 0.025 14.6 0.2 0.04 13.9 0.1 1.5 2 0 0 2 2 1 0 Helix-turn-helix domain Ribosomal_S25 PF03297.15 EGG41343.1 - 0.025 14.7 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 S25 ribosomal protein RNA_pol_Rpc34 PF05158.12 EGG41343.1 - 0.028 13.8 0.1 0.032 13.6 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF4194 PF13835.6 EGG41343.1 - 0.03 14.1 0.1 0.036 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) PadR PF03551.14 EGG41343.1 - 0.036 14.0 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2250 PF10007.9 EGG41343.1 - 0.051 13.7 0.1 0.093 12.9 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Cdc6_C PF09079.11 EGG41343.1 - 0.055 13.5 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HTH_20 PF12840.7 EGG41343.1 - 0.064 13.3 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 EGG41343.1 - 0.084 13.0 0.3 0.12 12.6 0.3 1.1 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_46 PF15977.5 EGG41343.1 - 0.11 12.6 0.9 0.16 12.0 0.6 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA binding Replic_Relax PF13814.6 EGG41343.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation THUMP PF02926.17 EGG41346.1 - 1.5e-13 51.1 1.8 1.6e-13 50.9 1.8 1.1 1 0 0 1 1 1 1 THUMP domain DEC-1_N PF04625.13 EGG41346.1 - 0.048 12.7 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PND PF17949.1 EGG41346.1 - 0.05 13.8 0.3 0.1 12.8 0.2 1.6 1 1 0 1 1 1 0 FANCM pseudonuclease domain ThiS PF02597.20 EGG41347.1 - 2.4e-07 31.3 0.1 9.6e-07 29.4 0.0 2.1 3 0 0 3 3 3 1 ThiS family CGI-121 PF08617.10 EGG41347.1 - 0.0002 21.6 3.1 0.00041 20.5 2.9 1.8 2 1 0 2 2 2 1 Kinase binding protein CGI-121 Urm1 PF09138.11 EGG41347.1 - 0.0042 17.4 2.6 0.0075 16.6 0.5 2.6 2 2 0 2 2 2 1 Urm1 (Ubiquitin related modifier) Staphostatin_A PF09022.10 EGG41347.1 - 0.62 10.0 8.5 0.84 9.6 1.1 3.1 2 1 1 3 3 3 0 Staphostatin A Ribosomal_S17e PF00833.18 EGG41348.1 - 1.5e-18 66.8 4.4 2.1e-18 66.4 4.4 1.3 1 1 0 1 1 1 1 Ribosomal S17 NUDIX_5 PF16705.5 EGG41348.1 - 0.014 15.2 1.5 0.13 12.0 0.3 2.0 1 1 1 2 2 2 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT DUF4201 PF13870.6 EGG41348.1 - 0.016 15.0 3.8 0.019 14.7 3.5 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TatD_DNase PF01026.21 EGG41349.1 - 1.4e-39 136.0 0.0 1.6e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase BP28CT PF08146.12 EGG41349.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 BP28CT (NUC211) domain CBFD_NFYB_HMF PF00808.23 EGG41350.1 - 1e-13 51.3 0.5 1.2e-13 51.1 0.5 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGG41350.1 - 4.9e-05 23.6 0.0 5.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGG41350.1 - 6.3e-05 23.3 0.2 7.4e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGG41350.1 - 0.00013 22.0 0.1 0.00015 21.8 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EGG41350.1 - 0.00074 19.5 0.0 0.00087 19.3 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGG41350.1 - 0.00092 19.3 0.0 0.0011 19.0 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.13 EGG41350.1 - 0.0014 19.1 0.0 0.0017 18.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAF PF02969.17 EGG41350.1 - 0.0067 16.6 0.5 0.0078 16.4 0.5 1.1 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1931 PF09123.11 EGG41350.1 - 0.0069 16.5 0.2 0.0077 16.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1931) DUF2120 PF09893.9 EGG41350.1 - 0.017 15.3 0.2 0.021 14.9 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) TFIID-18kDa PF02269.16 EGG41350.1 - 0.029 14.4 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIIB PF00382.19 EGG41350.1 - 0.065 13.3 0.1 0.094 12.8 0.1 1.3 1 0 0 1 1 1 0 Transcription factor TFIIB repeat MR_MLE_N PF02746.16 EGG41350.1 - 0.089 13.0 0.1 0.099 12.9 0.1 1.1 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TackOD1 PF18551.1 EGG41355.1 - 0.0055 16.4 4.6 0.01 15.5 4.6 1.4 1 1 0 1 1 1 1 Thaumarchaeal output domain 1 DUF4428 PF14471.6 EGG41355.1 - 0.02 14.8 5.5 0.023 14.6 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zf-C3HC4_3 PF13920.6 EGG41355.1 - 0.02 14.7 3.4 0.026 14.4 3.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SabA_adhesion PF18304.1 EGG41356.1 - 0.031 13.5 0.0 0.031 13.5 0.0 1.0 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain DUF2130 PF09903.9 EGG41357.1 - 8.9e-15 54.7 4.5 8.9e-15 54.7 4.5 2.9 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2130) Rad50_zn_hook PF04423.14 EGG41357.1 - 0.0084 15.9 0.4 0.0084 15.9 0.4 4.2 4 0 0 4 4 4 1 Rad50 zinc hook motif DUF3584 PF12128.8 EGG41357.1 - 1.4 6.3 37.0 0.069 10.7 28.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.21 EGG41357.1 - 3.8 7.0 40.1 0.95 9.0 20.9 3.0 2 1 1 3 3 3 0 Intermediate filament protein FA_synthesis PF02504.15 EGG41358.1 - 0.038 13.0 0.5 0.04 13.0 0.5 1.0 1 0 0 1 1 1 0 Fatty acid synthesis protein SWI2_SNF2 PF18766.1 EGG41360.1 - 1.2e-68 231.1 0.0 2.6e-68 230.0 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 EGG41360.1 - 1.2e-27 97.2 0.6 5.6e-27 95.0 0.0 2.3 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 EGG41360.1 - 3.6e-18 66.2 1.1 2.9e-17 63.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3387 PF11867.8 EGG41360.1 - 0.00014 21.4 9.1 0.069 12.5 5.5 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3387) Helicase_C PF00271.31 EGG41360.1 - 0.00034 20.9 0.0 0.0039 17.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UPF0137 PF03677.13 EGG41360.1 - 0.0044 16.8 2.4 0.0064 16.3 0.0 2.5 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0137) SH3BP5 PF05276.14 EGG41360.1 - 0.0094 15.8 0.4 4.1 7.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain-binding protein 5 (SH3BP5) RPN6_N PF18055.1 EGG41360.1 - 0.03 14.7 0.5 0.13 12.6 0.5 2.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Prp18 PF02840.15 EGG41360.1 - 0.032 14.3 4.9 0.11 12.5 1.7 2.6 2 0 0 2 2 2 0 Prp18 domain AAA_22 PF13401.6 EGG41360.1 - 0.075 13.3 0.1 0.63 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain NOG1_N PF17835.1 EGG41360.1 - 0.32 11.0 6.2 1.5 8.7 0.0 3.8 3 2 2 5 5 5 0 NOG1 N-terminal helical domain DUF3347 PF11827.8 EGG41360.1 - 0.78 9.9 3.3 0.7 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Cas_Cas02710 PF09670.10 EGG41361.1 - 1.4e-06 27.3 0.0 2.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) Cas_APE2256 PF09651.10 EGG41361.1 - 8.3e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_APE2256) UCR_Fe-S_N PF10399.9 EGG41361.1 - 0.0058 15.9 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cas_Csm6 PF09659.10 EGG41361.1 - 0.012 14.5 0.1 0.022 13.6 0.0 1.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) SBP_bac_1 PF01547.25 EGG41361.1 - 0.028 14.4 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cas_NE0113 PF09623.10 EGG41361.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) HSDR_N_2 PF13588.6 EGG41362.1 - 1.6e-10 40.9 1.3 4e-10 39.7 1.3 1.6 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) N6_Mtase PF02384.16 EGG41362.1 - 4.6e-08 32.7 1.5 1.1e-07 31.4 0.9 2.0 2 0 0 2 2 2 1 N-6 DNA Methylase HsdM_N PF12161.8 EGG41362.1 - 2.5e-06 28.2 0.6 1.2e-05 26.0 0.6 2.2 1 0 0 1 1 1 1 HsdM N-terminal domain MTS PF05175.14 EGG41362.1 - 0.021 14.4 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain DUF885 PF05960.11 EGG41363.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DrrA_P4M PF14860.6 EGG41363.1 - 0.13 12.1 0.8 0.48 10.3 0.6 1.9 1 1 1 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain PDDEXK_1 PF12705.7 EGG41364.1 - 8.8e-09 35.6 1.1 1.1e-08 35.3 1.1 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 EGG41364.1 - 6.2e-05 23.2 1.6 9e-05 22.6 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF83 DUF2800 PF10926.8 EGG41364.1 - 0.0055 16.0 0.3 0.0072 15.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) DUF3799 PF12684.7 EGG41364.1 - 0.019 14.7 3.5 0.03 14.1 3.2 1.4 1 1 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) HNH_3 PF13392.6 EGG41365.1 - 7.1e-06 25.7 2.4 1.3e-05 24.8 2.4 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EGG41365.1 - 0.002 18.2 2.2 0.002 18.2 2.2 1.7 2 0 0 2 2 2 1 HNH endonuclease HTH_DeoR PF08220.12 EGG41365.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HNH_5 PF14279.6 EGG41365.1 - 0.066 13.1 1.4 0.26 11.2 1.4 1.9 1 1 0 1 1 1 0 HNH endonuclease Phage_integrase PF00589.22 EGG41366.1 - 1.6e-14 54.0 0.2 3e-14 53.2 0.2 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EGG41366.1 - 0.011 16.0 0.0 0.28 11.5 0.0 2.8 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HrcA PF01628.21 EGG41366.1 - 0.015 15.2 0.2 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 HrcA protein C terminal domain Tup_N PF08581.10 EGG41366.1 - 0.041 14.2 1.5 0.17 12.2 1.2 2.2 2 0 0 2 2 2 0 Tup N-terminal Phage_int_SAM_4 PF13495.6 EGG41366.1 - 0.048 14.1 0.7 0.44 11.0 0.0 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF2680 PF10925.8 EGG41366.1 - 0.13 12.3 0.4 0.13 12.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) TFIIE_beta PF02186.15 EGG41366.1 - 0.22 11.8 0.2 0.22 11.8 0.2 3.7 4 0 0 4 4 4 0 TFIIE beta subunit core domain YgaB PF14182.6 EGG41366.1 - 0.93 9.9 4.1 1.3 9.5 0.4 3.0 2 1 1 3 3 3 0 YgaB-like protein Cupredoxin_1 PF13473.6 EGG41367.1 - 6.6e-11 42.3 0.0 8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 EGG41367.1 - 5.6e-09 36.3 0.0 1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family AIPR PF10592.9 EGG41368.1 - 6.2e-62 209.9 7.8 6.2e-62 209.9 7.8 2.0 2 0 0 2 2 2 1 AIPR protein RGS PF00615.19 EGG41368.1 - 0.067 13.5 0.2 0.35 11.2 0.1 2.3 2 1 0 2 2 2 0 Regulator of G protein signaling domain FAM221 PF14753.6 EGG41369.1 - 0.0009 18.9 1.3 0.0012 18.4 1.3 1.2 1 0 0 1 1 1 1 Protein FAM221A/B RNaseH_like PF04308.12 EGG41369.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Ribonuclease H-like HTH_45 PF14947.6 EGG41370.1 - 6.3e-17 61.3 0.6 7.6e-17 61.1 0.6 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 EGG41370.1 - 0.00021 21.1 0.4 0.0005 19.8 0.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4364) RNA_pol_Rpc34 PF05158.12 EGG41370.1 - 0.0036 16.7 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_34 PF13601.6 EGG41370.1 - 0.0038 17.4 0.4 0.0061 16.7 0.4 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain Mannosyl_trans2 PF04188.13 EGG41370.1 - 0.0064 15.9 0.0 0.0076 15.6 0.0 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Rrf2 PF02082.20 EGG41370.1 - 0.0088 16.4 0.2 0.016 15.5 0.2 1.5 2 0 0 2 2 2 1 Transcriptional regulator DUF505 PF04458.12 EGG41370.1 - 0.022 13.2 0.1 0.022 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) PadR PF03551.14 EGG41370.1 - 0.023 14.6 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Mrr_N PF14338.6 EGG41370.1 - 0.081 13.1 0.1 0.14 12.3 0.1 1.5 1 1 0 1 1 1 0 Mrr N-terminal domain PilN PF05137.13 EGG41370.1 - 0.081 13.1 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Fimbrial assembly protein (PilN) RPA_C PF08784.11 EGG41370.1 - 0.093 13.4 0.1 0.12 13.0 0.1 1.1 1 0 0 1 1 1 0 Replication protein A C terminal B-block_TFIIIC PF04182.12 EGG41370.1 - 0.094 12.9 0.4 0.18 12.0 0.2 1.5 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC V-set_2 PF15910.5 EGG41370.1 - 0.1 12.7 0.2 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 ICOS V-set domain TrmB PF01978.19 EGG41370.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB UbiA PF01040.18 EGG41371.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF1294 PF06961.13 EGG41372.1 - 0.14 12.5 1.3 5.3 7.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) PGM_PMM_I PF02878.16 EGG41373.1 - 1e-23 83.5 0.0 2.6e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGG41373.1 - 4.2e-15 55.9 0.1 2.8e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGG41373.1 - 6.6e-12 46.0 0.0 1.8e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGG41373.1 - 8.8e-07 29.0 0.0 3.3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AIRS PF00586.24 EGG41374.1 - 1.6e-13 51.1 0.0 3.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 EGG41374.1 - 0.00032 20.9 0.0 0.0005 20.2 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain PIG-P PF08510.12 EGG41375.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 PIG-P Ribosomal_S11 PF00411.19 EGG41376.1 - 1.2e-41 141.6 1.9 1.5e-41 141.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EGG41376.1 - 0.041 14.1 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) dsDNA_bind PF01984.20 EGG41378.1 - 3e-06 27.5 0.5 3.6e-06 27.2 0.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.9 EGG41378.1 - 0.0038 17.7 1.7 0.0063 16.9 1.7 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region DDRGK PF09756.9 EGG41378.1 - 0.43 10.2 3.8 1.5 8.4 3.7 2.1 1 1 0 1 1 1 0 DDRGK domain RtcB PF01139.17 EGG41379.1 - 4e-166 553.3 0.1 4.5e-166 553.1 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Complex1_LYR PF05347.15 EGG41379.1 - 0.022 14.8 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) HEPN PF05168.14 EGG41384.1 - 0.56 10.4 4.1 0.71 10.0 0.1 2.9 2 2 1 3 3 3 0 HEPN domain Lyase_1 PF00206.20 EGG41385.1 - 3e-49 168.1 1.4 4.8e-49 167.4 1.4 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EGG41385.1 - 3.7e-14 53.0 0.0 8.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 EGG41385.1 - 0.0072 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Asn_synthase PF00733.21 EGG41386.1 - 4.4e-27 95.7 0.0 6.7e-21 75.3 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase NAD_synthase PF02540.17 EGG41386.1 - 1.4e-06 27.6 0.1 6.9e-06 25.3 0.0 1.9 2 1 0 2 2 2 1 NAD synthase QueC PF06508.13 EGG41386.1 - 0.0019 17.7 0.1 0.0049 16.4 0.1 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC RE_CfrBI PF09516.10 EGG41386.1 - 0.022 14.2 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 CfrBI restriction endonuclease PI31_Prot_N PF11566.8 EGG41386.1 - 0.071 12.9 0.1 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 PI31 proteasome regulator N-terminal Pterin_4a PF01329.19 EGG41387.1 - 7.5e-33 112.6 0.2 8.1e-33 112.5 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 EGG41387.1 - 0.036 14.2 0.1 0.062 13.4 0.1 1.5 1 1 0 1 1 1 0 Translation-initiation factor 2 PTPS PF01242.19 EGG41388.1 - 1.4e-19 70.2 0.1 4e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase tRNA-synt_1 PF00133.22 EGG41389.1 - 1.6e-105 353.6 0.7 2.9e-104 349.5 0.7 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG41389.1 - 6.9e-31 107.3 2.8 6.9e-31 107.3 2.8 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG41389.1 - 4e-22 78.5 3.7 1.4e-11 43.8 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGG41389.1 - 0.00053 19.6 1.1 0.1 12.1 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 PWI PF01480.17 EGG41389.1 - 0.27 11.6 1.8 5.4 7.4 0.2 3.2 3 0 0 3 3 3 0 PWI domain LicD PF04991.13 EGG41391.1 - 0.032 14.4 0.4 0.053 13.6 0.4 1.3 1 0 0 1 1 1 0 LicD family Ribosomal_S30 PF04758.14 EGG41393.1 - 9.6e-11 41.7 3.2 1.5e-10 41.1 3.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S30 Radical_SAM PF04055.21 EGG41394.1 - 1.4e-07 32.0 0.0 3.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily NAD_binding_1 PF00175.21 EGG41395.1 - 1.9e-09 38.2 0.1 6.3e-09 36.5 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 EGG41395.1 - 1.7e-07 30.9 8.8 3.9e-07 29.8 8.8 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 EGG41395.1 - 0.0021 18.4 0.0 0.005 17.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGG41395.1 - 0.59 10.2 3.0 20 5.3 0.0 2.7 3 0 0 3 3 3 0 Ferric reductase NAD binding domain DHO_dh PF01180.21 EGG41396.1 - 1e-54 185.8 1.0 1.2e-54 185.6 1.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 EGG41396.1 - 4.4e-07 29.3 0.5 0.0003 20.0 0.2 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EGG41396.1 - 3e-05 23.6 0.3 0.046 13.2 0.0 2.6 3 0 0 3 3 3 2 Histidine biosynthesis protein NMO PF03060.15 EGG41396.1 - 0.00011 21.7 0.6 0.013 14.9 0.0 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase DUF561 PF04481.12 EGG41396.1 - 0.00021 20.5 8.2 0.00046 19.4 0.1 3.6 3 1 0 4 4 4 1 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 EGG41396.1 - 0.0006 19.3 1.3 1 8.7 0.2 2.7 3 0 0 3 3 3 2 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 EGG41396.1 - 0.002 17.5 2.8 0.28 10.4 0.9 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EGG41396.1 - 0.0033 16.5 0.7 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Antimicrobial_8 PF08103.11 EGG41396.1 - 0.079 13.1 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 Uperin family Nop PF01798.18 EGG41397.1 - 5.3e-09 35.9 0.2 1.8e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin TBP PF00352.21 EGG41398.1 - 1.4e-20 73.0 0.0 1.6e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGG41398.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) SHOCT PF09851.9 EGG41399.1 - 4.7e-07 29.3 6.6 8.2e-07 28.6 6.6 1.4 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.12 EGG41399.1 - 0.009 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Gas vesicle protein G TSP_NTD PF17804.1 EGG41399.1 - 0.011 16.1 4.1 0.013 15.8 4.1 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain RNA_pol_A_CTD PF03118.15 EGG41399.1 - 0.32 10.8 6.4 0.086 12.6 2.2 2.1 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain DRY_EERY PF09750.9 EGG41399.1 - 0.52 10.6 4.3 0.67 10.2 4.3 1.4 1 1 0 1 1 1 0 Alternative splicing regulator SHOCT PF09851.9 EGG41400.1 - 0.00028 20.5 4.9 0.00028 20.5 4.9 2.2 2 0 0 2 2 2 1 Short C-terminal domain UPF0730 PF15827.5 EGG41401.1 - 0.028 14.1 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 UPF0730 unknown protein family CTXphi_pIII-N1 PF16710.5 EGG41402.1 - 0.049 13.8 0.1 0.12 12.5 0.0 1.7 1 1 1 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII TruB_N PF01509.18 EGG41403.1 - 2.4e-25 89.7 0.2 3.2e-15 56.8 0.0 3.2 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EGG41403.1 - 4.7e-20 71.3 0.1 8e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 EGG41403.1 - 1.1e-19 70.3 0.0 5.6e-19 68.0 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain DKCLD PF08068.12 EGG41403.1 - 4.5e-12 45.9 0.0 1.3e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 DKCLD (NUC011) domain UPF0113 PF03657.13 EGG41403.1 - 0.056 13.7 0.0 0.44 10.9 0.0 2.4 2 0 0 2 2 2 0 UPF0113 PUA domain AAA_18 PF13238.6 EGG41404.1 - 3.6e-12 46.9 0.0 5.1e-12 46.5 0.0 1.2 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EGG41404.1 - 1.4e-11 44.9 0.3 3.2e-10 40.4 0.3 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 EGG41404.1 - 2.1e-09 37.9 0.0 3.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGG41404.1 - 1.2e-07 31.7 0.2 8.2e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 Cytidylate kinase ADK PF00406.22 EGG41404.1 - 2e-05 24.7 0.3 6.5e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Adenylate kinase SKI PF01202.22 EGG41404.1 - 3e-05 24.2 0.3 0.00076 19.6 0.3 2.2 1 1 0 1 1 1 1 Shikimate kinase AAA PF00004.29 EGG41404.1 - 6.5e-05 23.4 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG41404.1 - 0.00031 20.7 0.0 0.0005 20.0 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 EGG41404.1 - 0.00052 20.3 0.0 0.00094 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG41404.1 - 0.00067 19.8 0.1 0.0011 19.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EGG41404.1 - 0.0019 18.5 0.1 0.0045 17.3 0.0 1.6 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain KTI12 PF08433.10 EGG41404.1 - 0.0032 17.0 0.1 0.011 15.2 0.1 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 dNK PF01712.19 EGG41404.1 - 0.0033 17.3 0.5 0.092 12.6 0.1 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase DUF3616 PF12275.8 EGG41404.1 - 0.0038 16.7 0.3 0.0061 16.0 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3616) RNA_helicase PF00910.22 EGG41404.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EGG41404.1 - 0.0075 16.3 0.2 0.055 13.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG41404.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF4960 PF16324.5 EGG41404.1 - 0.0091 15.6 0.7 0.011 15.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4960) RTX_C PF08339.10 EGG41404.1 - 0.016 15.3 0.6 0.02 15.0 0.6 1.2 1 0 0 1 1 1 0 RTX C-terminal domain RuvB_N PF05496.12 EGG41404.1 - 0.016 14.9 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGG41404.1 - 0.019 15.4 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGG41404.1 - 0.03 14.6 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG41404.1 - 0.08 12.8 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NTPase Nif11 PF07862.11 EGG41404.1 - 0.092 13.1 1.1 0.32 11.3 0.0 2.4 3 0 0 3 3 2 0 Nif11 domain Guanylate_kin PF00625.21 EGG41404.1 - 0.12 12.1 1.3 2.7 7.6 0.0 2.4 2 1 0 2 2 2 0 Guanylate kinase EMC3_TMCO1 PF01956.16 EGG41405.1 - 7.5e-16 58.3 14.6 3.9e-15 56.0 14.6 1.8 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF2208 PF09973.9 EGG41405.1 - 0.73 9.4 9.4 0.3 10.7 3.6 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2208) DUF4199 PF13858.6 EGG41405.1 - 3.6 8.0 8.7 7 7.0 7.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) AAA_17 PF13207.6 EGG41406.1 - 1.9e-32 112.5 0.0 2.7e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG41406.1 - 1.1e-06 29.2 0.0 1.8e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGG41406.1 - 7.2e-05 22.4 0.3 0.0001 21.9 0.3 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Roc PF08477.13 EGG41406.1 - 7.8e-05 22.9 0.1 0.00014 22.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EGG41406.1 - 8e-05 22.6 2.4 0.0012 18.8 0.4 2.2 1 1 0 2 2 2 1 NTPase AAA_28 PF13521.6 EGG41406.1 - 0.00015 22.1 0.0 0.00022 21.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG41406.1 - 0.00024 20.9 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGG41406.1 - 0.00036 20.5 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.22 EGG41406.1 - 0.00039 20.1 0.3 0.00077 19.1 0.2 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 EGG41406.1 - 0.00041 20.8 0.1 0.0008 19.8 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGG41406.1 - 0.00059 20.4 1.2 0.00071 20.1 1.2 1.5 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EGG41406.1 - 0.00065 20.0 0.0 0.00089 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGG41406.1 - 0.00073 19.5 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGG41406.1 - 0.00074 19.9 0.2 0.001 19.4 0.2 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EGG41406.1 - 0.00077 19.1 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGG41406.1 - 0.0015 18.6 0.5 0.0022 18.1 0.5 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG41406.1 - 0.0019 18.4 0.0 0.0029 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG41406.1 - 0.0024 18.3 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EGG41406.1 - 0.0027 17.4 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 EGG41406.1 - 0.0032 17.3 0.2 0.0061 16.5 0.2 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 EGG41406.1 - 0.0075 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 EGG41406.1 - 0.0076 16.1 0.3 0.017 14.9 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGG41406.1 - 0.011 15.7 0.5 0.026 14.4 0.2 1.7 2 0 0 2 2 2 0 RsgA GTPase CLP1_P PF16575.5 EGG41406.1 - 0.011 15.5 0.2 0.19 11.5 0.0 2.6 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 EGG41406.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGG41406.1 - 0.014 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MeaB PF03308.16 EGG41406.1 - 0.015 14.3 0.2 0.026 13.5 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EGG41406.1 - 0.018 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ras PF00071.22 EGG41406.1 - 0.022 14.3 0.5 0.044 13.4 0.3 1.6 2 0 0 2 2 1 0 Ras family DnaB_C PF03796.15 EGG41406.1 - 0.023 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 EGG41406.1 - 0.027 14.5 0.6 0.059 13.4 0.1 1.8 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGG41406.1 - 0.038 13.2 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 EGG41406.1 - 0.048 13.3 0.3 0.15 11.8 0.3 2.1 1 1 0 1 1 1 0 Thymidylate kinase SecY PF00344.20 EGG41407.1 - 2.6e-61 207.5 16.8 3.3e-61 207.2 16.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGG41407.1 - 1.7e-11 43.7 0.7 6.2e-11 41.9 0.7 2.1 1 0 0 1 1 1 1 Plug domain of Sec61p Ribosomal_L27A PF00828.19 EGG41408.1 - 3.1e-15 57.0 0.1 4.5e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 EGG41408.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L30 PF00327.20 EGG41409.1 - 3.3e-12 46.1 0.0 5.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e FeS PF04060.13 EGG41409.1 - 0.15 11.7 0.7 0.74 9.5 0.0 2.3 3 0 0 3 3 3 0 Putative Fe-S cluster Ribosomal_S5 PF00333.20 EGG41410.1 - 4.3e-22 77.9 0.8 7.9e-22 77.0 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGG41410.1 - 3.6e-16 58.4 0.3 8.4e-16 57.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain RhlB PF12300.8 EGG41410.1 - 1.4 9.0 11.6 2.1 8.4 11.6 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Ribosomal_L5e PF17144.4 EGG41411.1 - 3.9e-15 56.2 2.5 1.7e-11 44.4 0.8 2.7 1 1 1 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18p PF00861.22 EGG41411.1 - 0.0046 17.3 0.3 0.0063 16.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast OTCace PF00185.24 EGG41412.1 - 1.3e-51 174.8 0.0 1.9e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EGG41412.1 - 3e-49 166.8 0.1 4.2e-49 166.4 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SRP54 PF00448.22 EGG41413.1 - 8.9e-70 234.3 0.6 1.2e-69 233.8 0.6 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EGG41413.1 - 2.6e-09 37.2 4.4 2.6e-09 37.2 4.4 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 EGG41413.1 - 4.6e-07 29.7 0.1 9.3e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGG41413.1 - 1.6e-05 24.3 0.1 2.7e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 EGG41413.1 - 0.00013 22.3 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGG41413.1 - 0.0013 19.1 0.0 0.0013 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain cobW PF02492.19 EGG41413.1 - 0.0016 18.1 0.9 0.012 15.2 0.9 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGG41413.1 - 0.0016 18.8 0.0 0.0042 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGG41413.1 - 0.0024 18.0 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Trypan_PARP PF05887.11 EGG41413.1 - 0.004 17.1 60.4 0.004 17.1 60.4 2.9 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) AAA_19 PF13245.6 EGG41413.1 - 0.0064 16.8 0.0 0.0099 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG41413.1 - 0.0067 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EGG41413.1 - 0.0074 15.6 0.1 0.0074 15.6 0.1 1.6 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 EGG41413.1 - 0.015 15.2 0.1 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase CbiA PF01656.23 EGG41413.1 - 0.017 15.2 0.1 0.065 13.3 0.0 2.0 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 EGG41413.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase TK PF00265.18 EGG41413.1 - 0.021 14.7 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_14 PF13173.6 EGG41413.1 - 0.023 14.7 0.0 0.081 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain TPP_enzyme_M PF00205.22 EGG41413.1 - 0.03 14.1 0.2 0.28 10.9 0.1 2.4 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain NTPase_1 PF03266.15 EGG41413.1 - 0.031 14.2 0.5 1.3 9.0 0.5 2.3 1 1 0 1 1 1 0 NTPase DAP3 PF10236.9 EGG41413.1 - 0.039 13.1 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 EGG41413.1 - 0.041 14.4 0.0 0.097 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 EGG41413.1 - 0.041 13.6 0.0 0.041 13.6 0.0 2.1 3 0 0 3 3 1 0 Thymidylate kinase KdpD PF02702.17 EGG41413.1 - 0.042 13.3 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_7 PF12775.7 EGG41413.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region KTI12 PF08433.10 EGG41413.1 - 0.062 12.7 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 EGG41413.1 - 0.095 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 EGG41413.1 - 0.096 11.7 0.1 0.3 10.0 0.1 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EGG41413.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGG41413.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain B12-binding PF02310.19 EGG41413.1 - 0.16 12.0 0.1 0.47 10.5 0.1 1.8 1 1 0 1 1 1 0 B12 binding domain MMR_HSR1 PF01926.23 EGG41413.1 - 0.23 11.6 1.6 0.85 9.7 0.3 2.5 1 1 1 2 2 2 0 50S ribosome-binding GTPase SPOUT_MTase PF02590.17 EGG41413.1 - 0.48 10.4 0.0 0.48 10.4 0.0 2.5 2 1 1 3 3 3 0 Predicted SPOUT methyltransferase DUF3408 PF11888.8 EGG41413.1 - 7.9 6.6 18.1 1.9 8.6 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Prefoldin PF02996.17 EGG41414.1 - 9.1e-16 57.9 8.5 3.5e-15 56.0 8.5 1.8 1 1 0 1 1 1 1 Prefoldin subunit LMP PF04778.12 EGG41414.1 - 0.00082 19.3 0.8 0.0011 18.9 0.2 1.5 2 0 0 2 2 2 1 LMP repeated region Ribosomal_L5 PF00281.19 EGG41414.1 - 0.044 14.1 0.9 0.17 12.3 0.2 2.4 3 0 0 3 3 3 0 Ribosomal protein L5 DUF3848 PF12959.7 EGG41414.1 - 0.2 11.7 2.6 0.27 11.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3848) TMF_TATA_bd PF12325.8 EGG41414.1 - 0.21 11.8 8.8 0.64 10.3 0.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.20 EGG41414.1 - 0.27 11.2 11.0 0.057 13.4 1.6 2.3 2 1 0 2 2 2 0 Prefoldin subunit OmpH PF03938.14 EGG41414.1 - 0.31 11.4 13.5 0.56 10.5 2.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Paralemmin PF03285.15 EGG41414.1 - 0.37 10.3 5.2 2.5 7.6 0.7 2.0 2 0 0 2 2 2 0 Paralemmin TSNAXIP1_N PF15739.5 EGG41414.1 - 1.7 9.1 10.2 0.11 12.9 2.2 2.1 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus ABC_tran_CTD PF16326.5 EGG41414.1 - 1.7 9.0 11.1 0.13 12.5 3.0 2.3 2 1 0 2 2 2 0 ABC transporter C-terminal domain CLZ PF16526.5 EGG41414.1 - 2.9 8.3 7.8 6.5 7.2 1.6 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3947 PF13135.6 EGG41414.1 - 3.7 7.8 6.9 5.8 7.2 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3947) Sod_Fe_C PF02777.18 EGG41415.1 - 1.1e-38 131.5 0.1 1.8e-38 130.8 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGG41415.1 - 1.8e-29 102.0 1.5 3.2e-29 101.2 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_S8 PF00082.22 EGG41416.1 - 1e-53 182.6 0.5 1.6e-53 181.9 0.5 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 EGG41416.1 - 1.1e-10 41.4 0.2 4.5e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 PA domain DeoC PF01791.9 EGG41416.1 - 0.056 13.1 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase PEPCK_ATP PF01293.20 EGG41417.1 - 1.8e-214 712.7 0.0 2.1e-214 712.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ribosomal_L32e PF01655.18 EGG41419.1 - 3.2e-31 108.0 0.0 3.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Mnd1 PF03962.15 EGG41419.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Mnd1 HTH domain Ribosomal_L19e PF01280.20 EGG41420.1 - 4.8e-39 133.7 8.5 5.7e-39 133.5 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DNA_binding_1 PF01035.20 EGG41421.1 - 1.9e-29 101.6 0.0 2.2e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain tRNA_deacylase PF04414.12 EGG41422.1 - 5.7e-59 199.1 0.0 7.4e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase SecE PF00584.20 EGG41423.1 - 4.5e-07 29.7 0.0 5.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Frag1 PF10277.9 EGG41423.1 - 0.026 14.1 0.0 0.028 13.9 0.0 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Spt5-NGN PF03439.13 EGG41424.1 - 2.6e-20 72.1 0.0 4.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 EGG41424.1 - 1.7e-05 24.6 0.3 3.3e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 KOW motif Ribosomal_L11_N PF03946.14 EGG41425.1 - 9.6e-23 79.8 1.3 1.7e-22 79.0 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGG41425.1 - 1e-19 70.8 1.2 2e-19 69.9 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Hom_end PF05204.14 EGG41425.1 - 0.11 12.7 0.3 0.17 12.1 0.3 1.3 1 0 0 1 1 1 0 Homing endonuclease AsnC_trans_reg PF01037.21 EGG41426.1 - 8.7e-16 57.7 0.1 1.1e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EGG41426.1 - 1.3e-08 34.2 0.1 2.3e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EGG41426.1 - 0.00021 21.1 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain B-block_TFIIIC PF04182.12 EGG41426.1 - 0.00072 19.7 0.1 0.00099 19.2 0.1 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.22 EGG41426.1 - 0.0078 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 MarR family Ribosomal_S25 PF03297.15 EGG41426.1 - 0.018 15.2 2.5 0.027 14.7 0.4 2.0 2 0 0 2 2 2 0 S25 ribosomal protein HTH_11 PF08279.12 EGG41426.1 - 0.036 14.0 0.1 0.086 12.8 0.1 1.7 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 EGG41426.1 - 0.042 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_psq PF05225.16 EGG41426.1 - 0.14 11.9 0.1 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Ribosomal_L1 PF00687.21 EGG41427.1 - 4.2e-38 131.1 1.8 5.4e-38 130.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RL10P_insert PF17777.1 EGG41428.1 - 2e-20 72.5 0.1 4.6e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGG41428.1 - 1e-18 67.3 0.6 1e-18 67.3 0.6 2.1 2 1 0 2 2 2 1 Ribosomal protein L10 HPHLAWLY PF14925.6 EGG41428.1 - 0.11 11.2 0.6 0.17 10.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function UPF0126 PF03458.13 EGG41429.1 - 3e-35 120.0 23.3 3.4e-18 65.3 7.8 2.4 3 0 0 3 3 3 2 UPF0126 domain Ribosomal_60s PF00428.19 EGG41430.1 - 5.5e-11 42.9 15.6 6.3e-11 42.7 15.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PseudoU_synth_1 PF01416.20 EGG41430.1 - 0.07 13.6 0.1 0.085 13.3 0.1 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase PepSY_2 PF13670.6 EGG41430.1 - 0.48 10.4 6.4 0.45 10.6 3.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain CBP_BcsF PF11120.8 EGG41431.1 - 0.15 12.2 0.0 0.69 10.1 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF DUF3040 PF11239.8 EGG41432.1 - 0.0065 16.7 7.1 0.008 16.4 6.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3040) DUF3188 PF11384.8 EGG41432.1 - 0.009 15.7 6.7 0.12 12.1 1.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3188) DUF981 PF06168.11 EGG41432.1 - 0.087 12.7 8.1 0.097 12.6 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF3784 PF12650.7 EGG41432.1 - 0.31 11.3 10.5 0.36 11.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF4225 PF13988.6 EGG41432.1 - 0.43 10.1 6.0 0.51 9.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Claudin_2 PF13903.6 EGG41432.1 - 0.68 9.7 4.5 0.7 9.6 4.5 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Neurensin PF14927.6 EGG41432.1 - 1.1 9.0 6.8 1 9.1 5.1 1.7 1 1 1 2 2 2 0 Neurensin SdpI PF13630.6 EGG41432.1 - 2.2 8.5 9.9 2.7 8.2 9.9 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF2207 PF09972.9 EGG41432.1 - 2.9 6.6 8.4 3 6.5 8.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TBPIP PF07106.13 EGG41433.1 - 0.019 14.9 0.5 0.051 13.5 0.1 2.0 2 1 0 2 2 2 0 TBPIP/Hop2 winged helix domain DUF3240 PF11582.8 EGG41433.1 - 0.059 13.5 0.1 0.096 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) SMC_ScpA PF02616.14 EGG41433.1 - 0.084 12.8 0.0 0.096 12.6 0.0 1.0 1 0 0 1 1 1 0 Segregation and condensation protein ScpA DDE_Tnp_IS240 PF13610.6 EGG41434.1 - 6.1e-22 78.4 0.9 1.2e-21 77.5 0.2 1.8 2 0 0 2 2 2 1 DDE domain rve PF00665.26 EGG41434.1 - 8.1e-08 32.5 0.2 1.8e-07 31.4 0.1 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 EGG41434.1 - 3.9e-06 26.5 0.2 1e-05 25.2 0.2 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS66 PF03050.14 EGG41434.1 - 0.00068 19.2 0.2 0.0014 18.2 0.2 1.6 1 0 0 1 1 1 1 Transposase IS66 family SWIM PF04434.17 EGG41434.1 - 0.003 17.2 2.7 0.007 16.0 2.7 1.6 1 0 0 1 1 1 1 SWIM zinc finger Zn_Tnp_IS1 PF03811.13 EGG41434.1 - 0.0054 16.4 0.7 0.022 14.5 0.7 2.1 1 0 0 1 1 1 1 InsA N-terminal domain Alpha-amylase_N PF02903.14 EGG41434.1 - 0.027 14.6 0.3 0.027 14.6 0.3 1.9 2 0 0 2 2 2 0 Alpha amylase, N-terminal ig-like domain HTH_23 PF13384.6 EGG41434.1 - 0.039 13.8 0.0 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain zf-Dof PF02701.15 EGG41434.1 - 0.076 13.2 2.9 0.23 11.6 2.9 1.8 1 0 0 1 1 1 0 Dof domain, zinc finger Terminase_5 PF06056.12 EGG41434.1 - 0.11 12.4 0.2 0.48 10.3 0.2 2.1 1 1 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 EGG41434.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3169 PF11368.8 EGG41436.1 - 0.076 12.5 3.0 0.075 12.5 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MazE_antitoxin PF04014.18 EGG41437.1 - 0.0093 15.9 0.1 0.014 15.3 0.1 1.5 1 1 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin TOBE PF03459.17 EGG41437.1 - 0.026 14.8 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 TOBE domain YcgR_2 PF12945.7 EGG41437.1 - 0.063 13.4 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein YcgR Wzz PF02706.15 EGG41438.1 - 0.0056 17.0 0.1 0.0067 16.7 0.1 1.1 1 0 0 1 1 1 1 Chain length determinant protein DUF1542 PF07564.11 EGG41438.1 - 0.034 14.3 2.0 0.053 13.6 2.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF4307 PF14155.6 EGG41438.1 - 0.16 11.8 0.3 0.18 11.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Methyltransf_25 PF13649.6 EGG41441.1 - 3.1e-08 34.2 0.0 5.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41441.1 - 5.1e-08 33.5 0.0 9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG41441.1 - 1.9e-07 31.0 0.0 3.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG41441.1 - 4e-07 30.0 0.0 5.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41441.1 - 1.1e-06 29.3 0.0 2.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EGG41441.1 - 3.4e-06 26.4 0.1 4.6e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 EGG41441.1 - 0.00061 19.5 0.0 0.00093 18.9 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EGG41441.1 - 0.0045 16.5 0.0 0.014 14.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Trm112p PF03966.16 EGG41441.1 - 0.015 15.8 0.3 0.14 12.8 0.2 2.6 2 1 0 2 2 2 0 Trm112p-like protein zf-CSL PF05207.13 EGG41441.1 - 0.035 13.8 0.5 0.072 12.8 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger CAAP1 PF15335.6 EGG41441.1 - 0.042 14.4 0.0 0.23 12.0 0.1 2.1 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 TF_Zn_Ribbon PF08271.12 EGG41441.1 - 0.085 12.4 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4423 PF14394.6 EGG41443.1 - 0.067 12.9 0.4 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) IZUMO PF15005.6 EGG41443.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated GAT PF03127.14 EGG41443.1 - 0.28 11.5 2.8 1.8 8.9 3.7 1.8 2 0 0 2 2 2 0 GAT domain Transglut_core2 PF13369.6 EGG41444.1 - 1.1e-40 138.8 0.0 1.4e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 EGG41444.1 - 3.8e-15 55.8 0.0 5.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG41444.1 - 0.00026 21.0 0.1 0.58 10.3 0.0 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 EGG41444.1 - 0.0006 19.5 0.1 1.4 8.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG41444.1 - 0.13 12.4 0.0 26 5.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG41444.1 - 0.14 13.1 0.0 3.6 8.7 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DivIC PF04977.15 EGG41445.1 - 0.0033 17.2 1.6 0.0046 16.7 1.6 1.4 1 1 0 1 1 1 1 Septum formation initiator CCD48 PF15799.5 EGG41445.1 - 0.035 12.4 0.1 0.035 12.4 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 NUDE_C PF04880.13 EGG41445.1 - 0.046 14.2 0.5 0.051 14.1 0.5 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF1192 PF06698.11 EGG41445.1 - 0.08 13.0 2.9 0.13 12.3 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) PhnA_Zn_Ribbon PF08274.12 EGG41446.1 - 0.039 13.9 1.1 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon OrfB_Zn_ribbon PF07282.11 EGG41446.1 - 0.04 13.8 0.3 0.043 13.8 0.3 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_4 PF14570.6 EGG41446.1 - 0.067 13.0 3.4 3.8 7.4 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4451 PF14616.6 EGG41446.1 - 0.14 12.4 0.8 0.3 11.3 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) EIF_2_alpha PF07541.12 EGG41447.1 - 0.094 12.8 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit YusW PF14039.6 EGG41448.1 - 0.05 14.1 0.0 0.09 13.3 0.0 1.4 1 0 0 1 1 1 0 YusW-like protein zf-C3HC4_3 PF13920.6 EGG41450.1 - 0.041 13.8 2.6 0.041 13.8 2.6 2.3 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) HATPase_c PF02518.26 EGG41451.1 - 3.7e-18 66.1 0.1 9.4e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 EGG41451.1 - 7.4e-14 52.1 11.6 7.4e-14 52.1 11.6 2.1 2 0 0 2 2 2 1 Cache domain HisKA PF00512.25 EGG41451.1 - 6.1e-11 42.2 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EGG41451.1 - 2.6e-06 27.2 0.0 2.6e-06 27.2 0.0 2.7 3 0 0 3 3 3 1 GHKL domain HAMP PF00672.25 EGG41451.1 - 0.00061 20.1 0.0 0.0018 18.6 0.0 1.9 1 0 0 1 1 1 1 HAMP domain LMSTEN PF07988.12 EGG41451.1 - 0.088 12.3 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 LMSTEN motif Response_reg PF00072.24 EGG41452.1 - 2.1e-24 85.8 1.0 2.4e-24 85.7 1.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF1102 PF06510.11 EGG41455.1 - 0.018 15.2 1.3 0.04 14.1 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1102) Metallophos PF00149.28 EGG41459.1 - 7.7e-19 69.0 0.4 1.1e-18 68.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG41459.1 - 1.9e-15 57.5 0.0 2.6e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGG41459.1 - 1.8e-06 27.5 0.1 0.0018 17.6 0.0 2.2 1 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily DUF2124 PF09897.9 EGG41459.1 - 0.0069 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) Iso_dh PF00180.20 EGG41460.1 - 2.6e-82 276.8 0.7 3e-82 276.6 0.7 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_31 PF13847.6 EGG41461.1 - 6.4e-09 35.8 0.4 2.4e-08 33.9 0.4 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41461.1 - 3.5e-07 30.8 0.0 6.7e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG41461.1 - 4.4e-06 26.3 0.0 1.2e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGG41461.1 - 7.5e-06 25.9 0.0 3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41461.1 - 5.2e-05 23.9 0.2 0.00014 22.6 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG41461.1 - 5.7e-05 23.7 0.1 0.00014 22.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG41461.1 - 0.00041 20.2 0.0 0.0011 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGG41461.1 - 0.0023 17.3 0.1 0.0032 16.9 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGG41461.1 - 0.0035 17.3 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EGG41461.1 - 0.036 13.1 0.0 0.2 10.7 0.0 1.9 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 EGG41461.1 - 0.096 12.1 0.1 0.21 10.9 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EGG41462.1 - 9.6e-40 136.3 1.0 1.3e-39 135.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EGG41462.1 - 8.2e-05 22.5 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EGG41462.1 - 0.0011 19.6 0.0 0.0028 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41462.1 - 0.018 15.8 0.0 0.067 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SAM_3 PF18016.1 EGG41462.1 - 0.034 14.0 0.1 8 6.4 0.0 2.7 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) Methyltransf_32 PF13679.6 EGG41462.1 - 0.05 13.6 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGG41462.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41462.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF655 PF04919.12 EGG41463.1 - 2.8e-49 167.5 0.2 3.2e-49 167.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.6 EGG41463.1 - 5.6e-05 23.3 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 EGG41463.1 - 0.0048 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RNA_pol_Rpb4 PF03874.16 EGG41464.1 - 7.9e-08 32.7 0.9 1.5e-07 31.8 0.9 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Integrase_Zn PF02022.19 EGG41464.1 - 0.0077 16.2 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 2 Integrase Zinc binding domain DUF4844 PF16133.5 EGG41464.1 - 0.027 15.0 0.3 0.049 14.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4844) Ribosomal_L21e PF01157.18 EGG41465.1 - 6.3e-19 67.7 1.8 7.9e-19 67.4 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L21e Radical_SAM PF04055.21 EGG41466.1 - 1.9e-19 70.6 0.0 3.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EGG41466.1 - 0.00032 20.8 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EGG41466.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Rad51 PF08423.11 EGG41467.1 - 2e-63 214.1 0.0 2.4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGG41467.1 - 0.00022 20.8 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EGG41467.1 - 0.00048 19.8 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain NARP1 PF12569.8 EGG41467.1 - 0.93 8.3 8.7 1.4 7.8 8.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 tRNA_int_endo PF01974.17 EGG41468.1 - 2e-19 69.5 0.3 3.7e-19 68.6 0.1 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGG41468.1 - 3.8e-13 48.9 4.5 1.2e-12 47.3 1.1 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Ribosomal_L16 PF00252.18 EGG41469.1 - 1.9e-24 86.1 0.3 2.3e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1492 PF07374.11 EGG41470.1 - 0.089 13.0 1.0 0.089 13.0 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) DUF5301 PF17225.3 EGG41470.1 - 1.1 9.7 6.7 0.19 12.2 2.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5300) Na_H_Exchanger PF00999.21 EGG41472.1 - 3.9e-51 174.0 55.6 5.2e-51 173.6 55.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YabQ PF09578.10 EGG41472.1 - 0.0028 17.8 1.0 0.0028 17.8 1.0 4.5 6 1 0 6 6 6 1 Spore cortex protein YabQ (Spore_YabQ) DUF1664 PF07889.12 EGG41474.1 - 5.9e-06 26.3 37.6 0.0059 16.7 1.9 5.8 1 1 4 5 5 5 4 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EGG41474.1 - 2.2e-05 24.8 38.9 0.32 11.5 2.5 6.5 2 2 4 7 7 7 4 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EGG41474.1 - 6.6e-05 23.1 2.1 6.6e-05 23.1 2.1 5.0 1 1 4 5 5 5 1 Fibrinogen alpha/beta chain family DUF948 PF06103.11 EGG41474.1 - 0.00053 20.2 31.8 0.96 9.8 3.0 6.1 1 1 4 5 5 5 2 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 EGG41474.1 - 0.0014 18.7 0.9 0.0014 18.7 0.9 5.0 2 2 4 6 6 6 1 Designed helical repeat protein 10 domain BLOC1_2 PF10046.9 EGG41474.1 - 0.0073 16.6 44.8 0.84 10.0 1.2 7.2 1 1 6 7 7 7 4 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 EGG41474.1 - 0.051 13.8 28.1 0.44 10.7 7.1 4.4 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Laminin_I PF06008.14 EGG41474.1 - 0.069 12.8 34.0 0.2 11.3 2.7 4.0 1 1 2 4 4 4 0 Laminin Domain I HSBP1 PF06825.12 EGG41474.1 - 0.12 12.2 20.2 0.48 10.3 0.0 6.1 5 1 1 6 6 5 0 Heat shock factor binding protein 1 MCPsignal PF00015.21 EGG41474.1 - 0.12 12.1 37.7 0.72 9.6 3.0 5.2 1 1 6 7 7 7 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 EGG41474.1 - 0.13 12.1 31.9 0.21 11.4 2.7 6.1 1 1 7 8 8 8 0 Sec34-like family DUF4088 PF13317.6 EGG41474.1 - 0.17 11.4 2.2 0.51 9.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) Cas_Cmr5 PF09701.10 EGG41474.1 - 0.22 11.8 6.0 0.49 10.7 0.6 3.4 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) DUF3450 PF11932.8 EGG41474.1 - 0.23 10.7 34.1 0.24 10.7 9.3 4.6 2 2 3 5 5 5 0 Protein of unknown function (DUF3450) Serine_rich PF08824.10 EGG41474.1 - 0.26 11.3 23.4 0.2 11.6 3.2 4.8 2 2 3 5 5 5 0 Serine rich protein interaction domain DUF3540 PF12059.8 EGG41474.1 - 0.29 10.9 6.0 1.4 8.7 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3540) Cauli_AT PF03233.13 EGG41474.1 - 0.39 10.6 39.0 0.46 10.4 0.3 5.1 2 2 3 5 5 5 0 Aphid transmission protein GIT1_C PF12205.8 EGG41474.1 - 0.64 10.1 25.1 0.29 11.3 2.8 4.6 3 1 1 4 4 3 0 G protein-coupled receptor kinase-interacting protein 1 C term HrpB7 PF09486.10 EGG41474.1 - 0.73 10.2 4.8 7.9 6.8 1.5 3.6 1 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) TolA_bind_tri PF16331.5 EGG41474.1 - 0.97 9.6 19.2 1.2 9.2 0.5 5.7 4 2 3 7 7 6 0 TolA binding protein trimerisation HD_4 PF13328.6 EGG41474.1 - 1.2 8.8 6.1 0.73 9.6 1.0 2.9 2 1 1 3 3 3 0 HD domain DUF745 PF05335.13 EGG41474.1 - 1.9 8.2 23.8 0.29 10.8 2.3 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF745) Occludin_ELL PF07303.13 EGG41474.1 - 2 9.2 21.9 2.6 8.8 0.1 5.1 2 2 3 5 5 5 0 Occludin homology domain Laminin_II PF06009.12 EGG41474.1 - 2.4 8.1 42.2 0.33 11.0 9.4 4.9 1 1 2 4 4 4 0 Laminin Domain II RPW8 PF05659.11 EGG41474.1 - 2.6 7.8 26.4 5.5 6.7 1.9 6.0 1 1 6 7 7 7 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FlaC_arch PF05377.11 EGG41474.1 - 2.8 8.4 33.9 1.8 9.0 0.3 7.8 3 1 4 7 7 7 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 EGG41474.1 - 3.7 8.0 25.4 0.25 11.7 0.4 5.7 4 2 2 6 6 6 0 Coiled-coil domain-containing protein 167 eIF3_N PF09440.10 EGG41474.1 - 4.3 7.8 26.7 1.2 9.6 4.4 4.9 2 2 2 4 4 3 0 eIF3 subunit 6 N terminal domain FliT PF05400.13 EGG41474.1 - 5.6 7.9 13.7 1.5 9.7 3.2 4.7 2 2 3 6 6 5 0 Flagellar protein FliT DUF3365 PF11845.8 EGG41474.1 - 6.5 7.1 7.1 0.96 9.8 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3365) zf-C4H2 PF10146.9 EGG41474.1 - 6.9 6.9 36.4 0.15 12.4 6.2 3.9 1 1 3 4 4 4 0 Zinc finger-containing protein Fez1 PF06818.15 EGG41474.1 - 7 7.0 32.9 12 6.3 9.6 3.7 1 1 3 4 4 4 0 Fez1 Mce4_CUP1 PF11887.8 EGG41474.1 - 8.3 5.8 11.3 7.5 5.9 0.3 4.0 1 1 3 5 5 5 0 Cholesterol uptake porter CUP1 of Mce4, putative Osmo_CC PF08946.10 EGG41474.1 - 9 6.6 9.8 35 4.7 0.1 5.0 4 1 1 5 5 5 0 Osmosensory transporter coiled coil Glyco_tranf_2_3 PF13641.6 EGG41475.1 - 2.8e-23 83.0 0.0 4.5e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGG41475.1 - 5.2e-19 68.9 0.5 9.3e-19 68.1 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGG41475.1 - 1.1e-17 64.4 0.0 1.9e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGG41475.1 - 5.1e-11 42.4 0.1 8.9e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 EGG41475.1 - 0.00029 19.5 1.5 0.0023 16.5 0.2 2.1 2 0 0 2 2 2 1 Cellulose synthase Glyco_tranf_2_4 PF13704.6 EGG41475.1 - 0.1 13.1 0.1 0.76 10.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Fer4 PF00037.27 EGG41476.1 - 5.8e-08 32.2 16.0 0.00016 21.3 3.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGG41476.1 - 1.5e-05 25.5 4.6 5.9e-05 23.6 5.1 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG41476.1 - 1.5e-05 25.0 3.9 2.8e-05 24.2 3.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG41476.1 - 5.5e-05 23.2 6.1 0.00012 22.1 6.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EGG41476.1 - 0.00027 21.0 3.7 0.00046 20.3 3.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain ETF_QO PF05187.13 EGG41476.1 - 0.00082 19.5 0.6 0.0015 18.6 0.6 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_6 PF12837.7 EGG41476.1 - 0.0036 17.3 13.1 0.005 16.9 1.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Tenui_PVC2 PF06656.11 EGG41476.1 - 0.0066 14.4 0.1 0.0093 13.9 0.1 1.1 1 0 0 1 1 1 1 Tenuivirus PVC2 protein Fer4_17 PF13534.6 EGG41476.1 - 0.027 15.0 2.0 9.6 6.8 0.9 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Me-amine-dh_L PF02975.14 EGG41476.1 - 0.093 13.2 2.1 0.17 12.4 2.1 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Fer4_16 PF13484.6 EGG41476.1 - 0.17 12.8 7.9 2.7 9.0 2.6 2.7 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EGG41476.1 - 0.36 11.3 5.7 5.2 7.6 6.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EGG41476.1 - 1.2 9.3 3.7 5.4 7.3 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG41476.1 - 2.5 8.4 9.4 4.9 7.5 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 EGG41476.1 - 2.8 8.5 9.5 0.56 10.8 0.6 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EGG41476.1 - 2.9 9.1 14.2 11 7.2 5.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Rhodanese PF00581.20 EGG41478.1 - 2.7e-35 121.1 0.4 4.9e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NAD_kinase PF01513.21 EGG41479.1 - 5.1e-35 121.1 0.4 7e-35 120.6 0.4 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGG41479.1 - 2.7e-06 27.0 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CoA_binding_2 PF13380.6 EGG41479.1 - 0.0019 18.7 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain PIN_6 PF17146.4 EGG41480.1 - 7.5e-09 36.0 0.1 1.2e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 PIN domain of ribonuclease PIN_5 PF08745.11 EGG41480.1 - 0.0036 16.7 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 PINc domain ribonuclease RecR PF02132.15 EGG41480.1 - 0.0057 16.2 0.2 0.015 14.9 0.1 1.8 2 0 0 2 2 2 1 RecR protein DZR PF12773.7 EGG41480.1 - 0.011 15.8 0.8 0.019 15.0 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 EGG41480.1 - 0.011 15.9 1.2 0.19 11.9 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_3 PF13920.6 EGG41480.1 - 0.026 14.4 0.8 0.041 13.7 0.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_ligase_ZBD PF03119.16 EGG41480.1 - 0.039 14.0 1.3 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1g PF09334.11 EGG41480.1 - 0.04 12.7 0.2 0.053 12.3 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) zinc-ribbons_6 PF07191.12 EGG41480.1 - 0.053 13.5 0.2 0.091 12.8 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbons Nudix_N_2 PF14803.6 EGG41480.1 - 0.066 13.2 4.3 0.16 11.9 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zf-TFIIB PF13453.6 EGG41480.1 - 0.13 11.6 2.3 9.3 5.7 0.3 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger OrfB_Zn_ribbon PF07282.11 EGG41480.1 - 0.26 11.2 1.7 0.95 9.4 1.5 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 EGG41480.1 - 0.64 9.8 5.8 1.1 9.1 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 EGG41480.1 - 1.1 9.2 5.7 6.8 6.7 5.7 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Rhodanese PF00581.20 EGG41481.1 - 2.2e-28 98.9 0.0 3.1e-15 56.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF412 PF04217.13 EGG41481.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF412 ERCC4 PF02732.15 EGG41482.1 - 1.5e-17 64.2 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 EGG41482.1 - 2.3e-09 37.7 0.0 2.7e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 EGG41482.1 - 2.3e-07 30.4 0.0 0.0036 17.1 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 EGG41482.1 - 4.4e-05 23.5 0.1 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 EGG41482.1 - 7e-05 23.0 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.6 EGG41482.1 - 0.0095 16.3 0.1 1.5 9.2 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 EGG41482.1 - 0.011 16.3 0.1 0.033 14.8 0.1 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Prefoldin_2 PF01920.20 EGG41483.1 - 1.5e-21 76.3 20.6 1.8e-21 76.1 20.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit Macoilin PF09726.9 EGG41483.1 - 1.8 7.0 9.9 2.2 6.8 9.9 1.0 1 0 0 1 1 1 0 Macoilin family FapA PF03961.13 EGG41483.1 - 3.7 6.1 11.3 5 5.6 11.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vir_act_alpha_C PF10400.9 EGG41483.1 - 5.2 7.8 10.0 0.39 11.4 1.8 2.3 1 1 1 2 2 2 0 Virulence activator alpha C-term Pcc1 PF09341.10 EGG41484.1 - 9.6e-06 25.6 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Svf1 PF08622.10 EGG41484.1 - 0.057 13.5 0.2 0.064 13.3 0.2 1.1 1 0 0 1 1 1 0 Svf1-like N-terminal lipocalin domain Ribosomal_L37ae PF01780.19 EGG41485.1 - 4.2e-19 68.4 1.9 4.6e-19 68.3 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EGG41485.1 - 0.00023 21.1 5.1 0.00028 20.8 3.1 1.9 2 0 0 2 2 2 1 Transposase zinc-ribbon domain C1_1 PF00130.22 EGG41485.1 - 0.014 15.3 2.3 0.018 14.9 2.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 EGG41485.1 - 0.019 14.9 3.3 0.034 14.1 3.3 1.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 EGG41485.1 - 0.044 13.3 1.6 0.075 12.6 1.6 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 EGG41485.1 - 0.059 13.5 0.3 0.059 13.5 0.3 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DUF1451 PF07295.11 EGG41485.1 - 0.74 9.8 4.1 0.55 10.3 0.8 1.9 1 1 1 2 2 2 0 Zinc-ribbon containing domain RNase_PH PF01138.21 EGG41486.1 - 1.1e-20 74.4 0.0 2.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG41486.1 - 1.5e-14 53.7 1.9 1.7e-14 53.6 0.1 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 SBBP PF06739.11 EGG41486.1 - 9.9 6.3 11.3 8.4 6.5 0.9 3.2 3 0 0 3 3 3 0 Beta-propeller repeat RNase_PH PF01138.21 EGG41487.1 - 2.1e-34 118.9 0.0 2.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG41487.1 - 4.4e-12 45.9 0.1 1e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_6 PF15985.5 EGG41488.1 - 2e-07 31.2 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 EGG41488.1 - 2.9e-07 30.2 0.2 6e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 EGG41488.1 - 0.00021 21.0 0.1 0.00042 20.1 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EGG41488.1 - 0.02 14.8 0.1 0.074 12.9 0.0 2.0 1 1 1 2 2 2 0 KH domain TAF PF02969.17 EGG41488.1 - 0.065 13.4 0.3 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) SBDS PF01172.18 EGG41489.1 - 8.4e-23 80.3 0.1 2e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EGG41489.1 - 5.3e-18 65.1 0.4 1.7e-17 63.5 0.1 1.8 2 0 0 2 2 2 1 SBDS protein C-terminal domain EFG_C PF00679.24 EGG41489.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus Transp_Tc5_C PF04236.15 EGG41490.1 - 0.13 12.6 1.9 0.98 9.8 0.2 2.1 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-RRN7 PF11781.8 EGG41491.1 - 0.017 14.8 0.2 0.017 14.8 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DNA_RNApol_7kD PF03604.13 EGG41491.1 - 0.16 11.7 4.3 1.3 8.7 0.7 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Spore-coat_CotZ PF10612.9 EGG41492.1 - 0.0046 17.1 0.0 0.0048 17.1 0.0 1.1 1 0 0 1 1 1 1 Spore coat protein Z DUF4284 PF14112.6 EGG41494.1 - 0.099 13.6 0.1 0.16 12.9 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 22 zf-C4pol PF14260.6 EGG41495.1 - 0.025 15.0 0.6 0.031 14.8 0.6 1.1 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Vps36-NZF-N PF16988.5 EGG41495.1 - 0.03 13.7 1.9 0.074 12.5 1.9 1.6 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain LIM PF00412.22 EGG41495.1 - 0.05 13.8 0.2 0.056 13.7 0.2 1.1 1 0 0 1 1 1 0 LIM domain RNA_pol_A_bac PF01000.26 EGG41497.1 - 7.5e-25 87.5 0.0 1.4e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGG41497.1 - 1.2e-14 53.5 0.0 1.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2401 PF10287.9 EGG41497.1 - 0.042 13.4 0.2 0.063 12.9 0.2 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Ribosomal_L18 PF17135.4 EGG41498.1 - 1.9e-07 30.7 0.0 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGG41498.1 - 0.00037 21.2 0.1 0.00054 20.6 0.1 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L13 PF00572.18 EGG41499.1 - 2.5e-12 47.2 0.4 6.1e-08 33.0 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L13 Ribosomal_S9 PF00380.19 EGG41500.1 - 1.4e-34 119.2 0.1 1.6e-34 119.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NFACT-R_1 PF05670.13 EGG41500.1 - 0.018 15.7 0.0 0.026 15.2 0.0 1.2 1 0 0 1 1 1 0 NFACT protein RNA binding domain NTP_transferase PF00483.23 EGG41501.1 - 4e-17 62.6 0.1 5e-17 62.3 0.1 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGG41501.1 - 3.7e-09 37.1 0.0 4.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Aconitase_C PF00694.19 EGG41502.1 - 4.5e-37 127.3 0.0 8.2e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 EGG41502.1 - 9.4e-05 22.1 0.2 0.0037 16.9 0.2 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus BET PF17035.5 EGG41502.1 - 0.55 10.5 4.8 7.9 6.7 0.1 2.9 2 1 1 3 3 3 0 Bromodomain extra-terminal - transcription regulation Aconitase PF00330.20 EGG41503.1 - 6.2e-153 510.1 0.0 7e-153 509.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG41504.1 - 1.1e-20 74.4 0.2 6.8e-20 71.7 0.0 2.2 2 1 0 2 2 2 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 EGG41504.1 - 0.002 17.8 0.2 0.0085 15.7 0.2 1.9 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase PF00330.20 EGG41505.1 - 1.9e-84 284.3 5.4 2.1e-82 277.6 5.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) SIMPL PF04402.14 EGG41507.1 - 5.5e-42 144.5 5.2 7e-42 144.2 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF1657 PF07870.11 EGG41507.1 - 0.067 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) MFS_1 PF07690.16 EGG41509.1 - 2.5e-48 164.8 74.9 2.9e-44 151.4 44.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG41509.1 - 1.2e-08 34.3 12.9 1.2e-08 34.3 12.9 3.5 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGG41509.1 - 0.00055 18.5 12.5 0.00055 18.5 12.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1523 PF07509.11 EGG41509.1 - 0.11 11.9 0.2 0.11 11.9 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1523) TMEM135_C_rich PF15982.5 EGG41509.1 - 0.67 10.6 4.7 0.38 11.4 1.1 2.4 1 1 2 3 3 3 0 N-terminal cysteine-rich region of Transmembrane protein 135 MFS_2 PF13347.6 EGG41509.1 - 2.1 6.8 45.4 0.48 8.9 4.0 4.5 1 1 1 4 4 4 0 MFS/sugar transport protein Elongin_A PF06881.11 EGG41510.1 - 0.035 14.6 3.0 0.046 14.2 3.0 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DASH_Dad4 PF08650.10 EGG41511.1 - 0.017 15.1 0.5 0.017 15.1 0.5 1.0 1 0 0 1 1 1 0 DASH complex subunit Dad4 Iron_permease PF04120.12 EGG41511.1 - 0.029 14.1 0.5 0.029 14.1 0.5 1.0 1 0 0 1 1 1 0 Low affinity iron permease HHH_2 PF12826.7 EGG41511.1 - 0.049 13.7 0.2 0.26 11.4 0.0 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF3378 PF11858.8 EGG41511.1 - 0.055 13.6 0.2 0.064 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) VATC PF18716.1 EGG41512.1 - 0.0011 18.7 4.5 0.0031 17.3 4.5 1.6 1 1 0 1 1 1 1 Vms1-associating treble clef domain DUF2116 PF09889.9 EGG41512.1 - 0.0094 15.9 1.1 0.0099 15.8 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-C6H2 PF15801.5 EGG41512.1 - 0.016 15.5 1.0 0.016 15.5 1.0 1.0 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF2256 PF10013.9 EGG41512.1 - 0.061 13.4 3.5 4.2 7.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) GBP_C PF02841.14 EGG41514.1 - 0.011 15.2 6.4 0.019 14.4 6.4 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HATPase_c PF02518.26 EGG41515.1 - 2e-21 76.6 0.3 4.2e-21 75.5 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG41515.1 - 1.9e-11 43.8 0.0 4.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EGG41515.1 - 1.2e-07 31.5 0.3 4.6e-07 29.7 0.3 2.0 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EGG41515.1 - 0.0001 22.1 0.1 0.00032 20.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG41515.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain bPH_5 PF10882.8 EGG41515.1 - 0.039 14.0 0.4 0.39 10.8 0.1 2.6 2 1 0 2 2 2 0 Bacterial PH domain CHASE3 PF05227.13 EGG41515.1 - 0.041 13.8 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 CHASE3 domain HATPase_c PF02518.26 EGG41516.1 - 1.4e-18 67.5 2.3 2.8e-18 66.5 0.4 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG41516.1 - 8.1e-08 32.2 0.0 2.7e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGG41516.1 - 0.00014 21.7 1.9 0.00027 20.8 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EGG41516.1 - 0.00051 19.9 0.6 0.00051 19.9 0.6 2.9 2 2 0 2 2 2 1 GHKL domain BSD PF03909.17 EGG41516.1 - 0.012 15.6 0.5 0.041 13.9 0.5 2.0 1 1 0 1 1 1 0 BSD domain HATPase_c_2 PF13581.6 EGG41516.1 - 0.045 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Uteroglobin PF01099.17 EGG41516.1 - 0.11 12.8 1.4 0.46 10.8 1.3 2.1 1 1 0 1 1 1 0 Uteroglobin family DUF2252 PF10009.9 EGG41516.1 - 0.63 9.0 2.9 0.97 8.4 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DDE_Tnp_IS66 PF03050.14 EGG41516.1 - 1.2 8.5 4.5 9.2 5.6 2.7 2.2 2 0 0 2 2 2 0 Transposase IS66 family Atg14 PF10186.9 EGG41516.1 - 2.7 7.0 16.0 3.9 6.5 16.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 F420_ligase PF01996.16 EGG41517.1 - 5.5e-15 55.4 0.5 6.7e-15 55.1 0.5 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase DUF3906 PF13046.6 EGG41517.1 - 0.033 14.3 0.2 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) SelB-wing_2 PF09106.11 EGG41517.1 - 0.16 12.2 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix F420_ligase PF01996.16 EGG41518.1 - 2.9e-13 49.7 0.0 3.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase TIR-like PF10137.9 EGG41519.1 - 0.051 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF473 PF04322.12 EGG41519.1 - 0.079 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF473) DUF2854 PF11016.8 EGG41522.1 - 0.16 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) TPP_enzyme_C PF02775.21 EGG41523.1 - 6.8e-29 100.6 0.2 1.1e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 EGG41523.1 - 4.8e-15 55.5 0.6 1.2e-13 51.0 0.6 2.4 1 1 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 EGG41524.1 - 7e-56 189.5 0.0 1e-55 189.0 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EGG41524.1 - 2.4e-26 92.9 0.0 4.9e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EGG41524.1 - 7.7e-12 45.4 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 EGG41524.1 - 2e-06 27.7 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain zf-ribbon_3 PF13248.6 EGG41525.1 - 0.002 17.4 7.5 0.0032 16.8 7.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EGG41525.1 - 0.026 14.2 8.8 0.052 13.3 8.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain 2-Hacid_dh_C PF02826.19 EGG41526.1 - 5.3e-61 205.1 0.1 7.9e-61 204.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG41526.1 - 1.7e-31 108.7 0.0 1.9e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 EGG41526.1 - 7.8e-07 28.8 0.6 1.4e-06 28.0 0.2 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 EGG41526.1 - 1.5e-06 28.5 0.2 2.7e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG41526.1 - 0.0011 19.5 0.1 0.0035 17.9 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 EGG41526.1 - 0.057 13.5 0.3 0.1 12.7 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HemS PF05171.12 EGG41527.1 - 2.5e-06 27.5 0.0 2.9e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Haemin-degrading HemS.ChuX domain ChuX_HutX PF06228.13 EGG41527.1 - 3.3e-06 26.9 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX MFS_1 PF07690.16 EGG41529.1 - 4.9e-08 32.3 22.1 6.7e-08 31.8 22.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGG41529.1 - 0.00012 21.1 11.8 0.00012 21.1 11.8 1.6 1 1 1 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 EGG41529.1 - 1.8 6.8 11.5 0.13 10.6 3.7 1.9 1 1 1 2 2 2 0 Transmembrane secretion effector PRA1 PF03208.19 EGG41529.1 - 9.2 5.9 11.4 2.2 7.9 7.5 1.7 1 1 1 2 2 2 0 PRA1 family protein Pyr_redox_2 PF07992.14 EGG41530.1 - 4.1e-40 137.8 0.0 5.1e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG41530.1 - 4.9e-12 46.3 0.2 2.4e-11 44.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG41530.1 - 3.8e-05 23.4 0.2 4.1 6.9 0.0 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG41530.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ACT_7 PF13840.6 EGG41531.1 - 3.4e-07 29.9 0.1 6.4e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 ACT domain SecD-TM1 PF13721.6 EGG41531.1 - 0.017 15.6 0.1 0.038 14.4 0.0 1.6 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Pox_A3L PF05288.11 EGG41531.1 - 0.034 14.1 0.0 0.16 12.0 0.0 2.1 1 0 0 1 1 1 0 Poxvirus A3L Protein HSP20 PF00011.21 EGG41532.1 - 1.2e-06 28.6 4.0 2.6e-05 24.3 4.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PIH1_CS PF18201.1 EGG41532.1 - 0.00053 20.3 0.2 0.00074 19.9 0.2 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 EGG41532.1 - 0.0032 17.0 0.1 0.0065 16.0 0.1 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA AAA PF00004.29 EGG41533.1 - 7e-100 330.6 0.0 9.3e-51 171.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG41533.1 - 7.8e-28 96.0 1.0 3.2e-13 49.2 0.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGG41533.1 - 8.6e-24 83.5 0.0 2.3e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EGG41533.1 - 3.1e-16 60.0 0.1 3.8e-07 30.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGG41533.1 - 2.3e-14 53.4 0.0 1.3e-07 31.5 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGG41533.1 - 3.5e-14 53.5 0.0 6e-06 26.7 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGG41533.1 - 5.1e-12 46.0 2.5 0.00026 21.0 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG41533.1 - 2.8e-10 40.6 1.9 0.0051 17.1 0.0 4.3 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 EGG41533.1 - 3.4e-10 39.7 0.1 0.00079 18.7 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 EGG41533.1 - 6.3e-10 39.4 0.0 0.00018 21.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGG41533.1 - 1e-09 38.5 0.0 0.00041 20.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain CDC48_2 PF02933.17 EGG41533.1 - 1.2e-09 37.8 0.6 3.2e-09 36.4 0.6 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 EGG41533.1 - 1.4e-08 34.4 0.3 0.0018 17.7 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGG41533.1 - 6.7e-08 32.5 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EGG41533.1 - 1.5e-07 32.0 0.1 0.0082 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGG41533.1 - 5.8e-07 29.4 0.0 0.01 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGG41533.1 - 6e-07 29.2 1.2 0.11 12.0 0.0 3.5 2 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EGG41533.1 - 1.2e-06 28.3 0.3 0.19 11.4 0.0 4.1 2 2 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EGG41533.1 - 1.4e-06 28.6 0.0 0.068 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 EGG41533.1 - 1.7e-06 27.4 0.2 0.012 14.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 EGG41533.1 - 2e-06 27.4 0.1 0.058 12.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EGG41533.1 - 2.9e-06 27.6 0.1 0.099 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EGG41533.1 - 6.8e-06 26.6 0.1 0.21 12.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.11 EGG41533.1 - 1.2e-05 25.1 0.0 0.034 14.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGG41533.1 - 3.3e-05 23.8 0.0 0.084 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EGG41533.1 - 4.3e-05 22.8 0.0 0.27 10.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TsaE PF02367.17 EGG41533.1 - 5.3e-05 23.2 0.2 0.49 10.4 0.1 2.7 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EGG41533.1 - 7.9e-05 21.9 0.2 0.16 11.1 0.1 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EGG41533.1 - 8e-05 22.4 0.3 0.17 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGG41533.1 - 0.00011 22.2 1.1 0.6 10.0 0.1 3.7 4 0 0 4 4 3 2 NACHT domain PhoH PF02562.16 EGG41533.1 - 0.00014 21.3 0.4 0.48 9.8 0.1 2.8 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 EGG41533.1 - 0.00047 19.5 0.0 0.48 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGG41533.1 - 0.0011 19.4 2.8 1.4 9.3 0.0 3.7 4 0 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.6 EGG41533.1 - 0.0014 18.7 0.0 2.2 8.4 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 EGG41533.1 - 0.0017 17.8 0.0 0.65 9.4 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein Guanylate_kin PF00625.21 EGG41533.1 - 0.0017 18.1 0.5 5.6 6.6 0.0 4.2 3 1 1 4 4 4 0 Guanylate kinase AFG1_ATPase PF03969.16 EGG41533.1 - 0.0024 16.8 0.0 0.78 8.6 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase UFD1 PF03152.14 EGG41533.1 - 0.0031 17.0 0.1 0.0058 16.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 ResIII PF04851.15 EGG41533.1 - 0.0041 17.1 0.1 0.75 9.8 0.0 2.9 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit CPT PF07931.12 EGG41533.1 - 0.0043 16.9 0.1 0.15 11.9 0.0 2.6 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EGG41533.1 - 0.005 17.3 0.0 3.5 8.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EGG41533.1 - 0.0059 16.5 0.0 0.44 10.4 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein NB-ARC PF00931.22 EGG41533.1 - 0.0094 15.2 0.2 4.1 6.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EGG41533.1 - 0.011 15.7 2.8 4.9 7.0 0.0 4.1 3 1 1 4 4 3 0 NTPase ATPase_2 PF01637.18 EGG41533.1 - 0.014 15.3 0.3 0.67 9.8 0.1 3.3 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EGG41533.1 - 0.018 14.1 0.0 2.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EGG41533.1 - 0.021 14.6 1.6 5.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase Viral_helicase1 PF01443.18 EGG41533.1 - 0.025 14.3 0.0 0.26 11.0 0.0 2.4 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EGG41533.1 - 0.03 14.0 0.0 7.4 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPT PF01745.16 EGG41533.1 - 0.032 13.6 0.5 2 7.7 0.1 2.5 2 0 0 2 2 2 0 Isopentenyl transferase PIF1 PF05970.14 EGG41533.1 - 0.043 13.0 0.0 4.7 6.3 0.0 2.8 2 0 0 2 2 2 0 PIF1-like helicase Torsin PF06309.11 EGG41533.1 - 0.066 13.3 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Torsin Vps4_C PF09336.10 EGG41533.1 - 0.067 13.2 4.2 0.76 9.8 0.1 3.3 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain ATPase PF06745.13 EGG41533.1 - 0.068 12.5 11.1 0.54 9.6 0.1 4.2 4 1 0 5 5 4 0 KaiC Rad17 PF03215.15 EGG41533.1 - 0.075 12.9 0.3 11 5.9 0.0 2.9 2 2 1 3 3 3 0 Rad17 P-loop domain Hydin_ADK PF17213.3 EGG41533.1 - 0.22 11.8 1.2 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_23 PF13476.6 EGG41533.1 - 4.7 7.7 7.7 3.2 8.2 0.2 3.6 2 2 0 2 2 2 0 AAA domain Evr1_Alr PF04777.13 EGG41534.1 - 0.012 16.1 0.1 0.013 15.9 0.1 1.1 1 0 0 1 1 1 0 Erv1 / Alr family dCMP_cyt_deam_1 PF00383.23 EGG41534.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Pox_vIL-18BP PF05566.12 EGG41534.1 - 0.14 12.4 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein TFIIB PF00382.19 EGG41535.1 - 8.2e-33 112.3 3.0 1.7e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat HTH_11 PF08279.12 EGG41535.1 - 9.5e-06 25.5 1.4 0.0055 16.6 0.1 2.6 2 0 0 2 2 2 2 HTH domain Cyclin_N PF00134.23 EGG41535.1 - 0.00087 19.0 0.2 0.48 10.2 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain Herpes_UL51 PF04540.13 EGG41535.1 - 0.05 13.3 0.2 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL51 protein DUF2543 PF10820.8 EGG41535.1 - 0.051 13.8 0.4 0.46 10.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2543) SoPB_HTH PF18090.1 EGG41535.1 - 0.14 12.3 0.6 1.2 9.3 0.1 2.7 3 0 0 3 3 3 0 Centromere-binding protein HTH domain DUF1059 PF06348.11 EGG41536.1 - 8.6e-08 32.3 0.1 1.4e-07 31.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1059) AAA_lid_9 PF17871.1 EGG41536.1 - 0.025 14.5 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 AAA lid domain CRCB PF02537.15 EGG41537.1 - 3.3e-19 69.0 4.5 3.9e-19 68.7 4.5 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF2104 PF09877.9 EGG41537.1 - 0.0032 17.7 1.4 0.0046 17.2 1.0 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2104) CBS PF00571.28 EGG41538.1 - 6.7e-26 90.5 4.7 1.1e-12 48.2 0.1 2.2 2 0 0 2 2 2 2 CBS domain Serpin PF00079.20 EGG41538.1 - 0.36 10.1 1.7 0.4 9.9 0.3 1.6 2 0 0 2 2 2 0 Serpin (serine protease inhibitor) Usp PF00582.26 EGG41539.1 - 6.3e-20 72.1 0.0 7e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family CBS PF00571.28 EGG41540.1 - 6.5e-27 93.8 1.5 7.6e-13 48.7 0.1 2.1 2 0 0 2 2 2 2 CBS domain Usp PF00582.26 EGG41542.1 - 2.1e-27 96.4 0.0 2.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DnaB_2 PF07261.11 EGG41542.1 - 0.038 13.7 0.3 0.07 12.9 0.3 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment Usp PF00582.26 EGG41543.1 - 1e-28 100.6 0.0 1.3e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 EGG41544.1 - 3e-31 108.8 0.0 3.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family PRORP PF16953.5 EGG41544.1 - 0.052 13.1 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P CBS PF00571.28 EGG41545.1 - 7.3e-29 100.0 7.8 2.6e-14 53.4 0.6 3.1 3 0 0 3 3 3 3 CBS domain CBS PF00571.28 EGG41546.1 - 4.6e-11 43.0 0.4 5.8e-11 42.7 0.4 1.2 1 0 0 1 1 1 1 CBS domain CBS PF00571.28 EGG41547.1 - 5.7e-23 81.1 1.2 4.2e-06 27.1 0.1 4.4 4 0 0 4 4 4 4 CBS domain NLE PF08154.12 EGG41547.1 - 0.012 16.1 0.6 5.1 7.7 0.0 3.1 3 0 0 3 3 3 0 NLE (NUC135) domain PAC2 PF09754.9 EGG41548.1 - 4.5e-32 111.8 0.0 5.1e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 PAC2 family HSP20 PF00011.21 EGG41549.1 - 1.8e-13 50.5 0.0 2.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG41549.1 - 2.1e-09 36.8 0.0 2.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EGG41549.1 - 0.0014 19.6 0.7 0.0014 19.6 0.7 1.5 2 0 0 2 2 2 1 CS domain PIH1_CS PF18201.1 EGG41549.1 - 0.035 14.5 0.0 0.073 13.5 0.0 1.6 1 1 0 1 1 1 0 PIH1 CS-like domain P-II PF00543.22 EGG41552.1 - 1.7e-08 35.0 1.4 2.8e-08 34.3 1.1 1.5 2 0 0 2 2 2 1 Nitrogen regulatory protein P-II P-II PF00543.22 EGG41553.1 - 2e-12 47.6 0.5 2.4e-12 47.3 0.5 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Ammonium_transp PF00909.21 EGG41554.1 - 2.2e-113 378.9 29.1 2.5e-113 378.8 29.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3188 PF11384.8 EGG41554.1 - 0.079 12.7 0.1 0.079 12.7 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3188) CopG_antitoxin PF12441.8 EGG41555.1 - 0.00033 21.1 0.7 0.0014 19.1 0.2 2.2 2 0 0 2 2 2 1 CopG antitoxin of type II toxin-antitoxin system RnlB_antitoxin PF15933.5 EGG41555.1 - 0.043 14.1 0.2 0.3 11.4 0.0 2.3 2 1 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA IL5 PF02025.15 EGG41556.1 - 0.00084 19.6 0.1 0.001 19.3 0.1 1.1 1 0 0 1 1 1 1 Interleukin 5 Alginate_exp PF13372.6 EGG41556.1 - 0.015 14.1 0.0 0.017 13.9 0.0 1.0 1 0 0 1 1 1 0 Alginate export RE_Alw26IDE PF09665.10 EGG41556.1 - 0.047 12.9 0.0 0.05 12.8 0.0 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) S_100 PF01023.19 EGG41556.1 - 0.057 13.1 3.4 2.9 7.7 0.2 2.3 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain CARDB PF07705.11 EGG41557.1 - 0.027 14.7 0.4 0.027 14.7 0.4 1.9 2 1 0 2 2 2 0 CARDB Big_4 PF07532.11 EGG41557.1 - 0.028 14.2 0.6 0.098 12.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) TFIIB PF00382.19 EGG41558.1 - 7e-33 112.5 6.2 8.5e-16 57.8 0.4 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG41558.1 - 8.1e-10 38.1 0.4 1.4e-09 37.3 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EGG41558.1 - 0.0067 16.2 0.3 0.075 12.8 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4 PF04545.16 EGG41558.1 - 0.0083 15.6 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 EGG41558.1 - 0.0086 16.0 0.2 0.33 10.9 0.0 2.8 3 0 0 3 3 3 1 HTH domain RPA_interact_C PF14768.6 EGG41558.1 - 0.016 15.8 0.0 0.046 14.3 0.0 1.9 1 0 0 1 1 1 0 Replication protein A interacting C-terminal HTH_AsnC-type PF13404.6 EGG41558.1 - 0.016 15.0 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 EGG41558.1 - 0.021 14.5 0.2 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 zinc_ribbon_2 PF13240.6 EGG41558.1 - 0.026 14.2 1.9 0.068 12.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 EGG41558.1 - 0.032 14.1 0.3 0.5 10.3 0.1 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Phage_terminase PF10668.9 EGG41558.1 - 0.055 13.5 0.2 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Phage terminase small subunit Baculo_ME53 PF06061.11 EGG41558.1 - 0.1 11.8 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 RB_B PF01857.20 EGG41558.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-piccolo PF05715.13 EGG41558.1 - 0.17 12.0 1.4 0.49 10.6 1.4 1.8 1 1 0 1 1 1 0 Piccolo Zn-finger Cyclin_C PF02984.19 EGG41558.1 - 0.2 11.8 0.3 8.2 6.5 0.0 2.3 1 1 0 2 2 2 0 Cyclin, C-terminal domain HTH_23 PF13384.6 EGG41558.1 - 0.22 11.4 1.8 0.54 10.1 0.0 2.5 3 0 0 3 3 2 0 Homeodomain-like domain Auto_anti-p27 PF06677.12 EGG41558.1 - 0.24 11.6 1.4 0.44 10.7 1.4 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) A2L_zn_ribbon PF08792.10 EGG41558.1 - 0.26 11.0 1.1 0.55 10.0 1.1 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 EGG41558.1 - 0.27 10.7 1.4 1.4 8.5 1.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-CCHC_5 PF14787.6 EGG41558.1 - 1.7 8.4 5.5 0.76 9.5 0.3 2.6 3 0 0 3 3 2 0 GAG-polyprotein viral zinc-finger APS_kinase PF01583.20 EGG41559.1 - 1.5e-50 171.2 0.0 1.8e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EGG41559.1 - 1.5e-06 28.4 0.0 2.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG41559.1 - 7.9e-05 23.2 0.0 0.00017 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGG41559.1 - 0.00011 21.6 0.0 0.00036 19.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 EGG41559.1 - 0.00081 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGG41559.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 EGG41559.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 EGG41559.1 - 0.049 13.5 0.1 6.3 6.6 0.0 2.3 1 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Arf PF00025.21 EGG41559.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Inositol_P PF00459.25 EGG41560.1 - 2.4e-20 73.2 0.4 2.7e-20 73.0 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 EGG41560.1 - 0.0017 17.8 0.1 0.0021 17.6 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CRPA PF05745.11 EGG41561.1 - 0.053 13.5 2.7 0.059 13.4 2.7 1.1 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Saf_2TM PF18303.1 EGG41561.1 - 7.2 6.2 8.4 1e+02 2.4 8.4 2.0 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain Holin_BlyA PF05102.12 EGG41561.1 - 7.9 6.5 11.7 3.4 7.7 2.0 2.1 1 1 1 2 2 2 0 holin, BlyA family adh_short_C2 PF13561.6 EGG41562.1 - 4.6e-72 242.4 0.0 5.6e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG41562.1 - 3.2e-60 202.9 0.5 3.9e-60 202.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG41562.1 - 1.1e-07 31.9 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EGG41562.1 - 0.008 15.5 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.25 EGG41562.1 - 0.017 14.8 0.0 0.031 13.9 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Epimerase PF01370.21 EGG41562.1 - 0.017 14.6 0.4 0.023 14.2 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGG41562.1 - 0.034 14.0 0.3 0.056 13.3 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EGG41562.1 - 0.061 13.3 0.1 0.43 10.6 0.1 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DUF758 PF05527.11 EGG41562.1 - 1.2 9.1 4.2 1.8 8.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF758) TFIIB PF00382.19 EGG41564.1 - 3.5e-33 113.5 1.6 8.8e-16 57.7 0.4 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG41564.1 - 3.7e-08 32.7 0.7 7e-08 31.9 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4 PF04545.16 EGG41564.1 - 0.00048 19.6 0.0 0.048 13.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Cyclin_N PF00134.23 EGG41564.1 - 0.0013 18.4 0.0 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain A2L_zn_ribbon PF08792.10 EGG41564.1 - 0.0022 17.6 0.6 0.0042 16.8 0.6 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain Cyclin_C PF02984.19 EGG41564.1 - 0.0045 17.1 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Ribosomal_L37e PF01907.19 EGG41564.1 - 0.059 13.5 0.3 0.16 12.2 0.3 1.8 1 0 0 1 1 1 0 Ribosomal protein L37e Sigma70_r4_2 PF08281.12 EGG41564.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 NOB1_Zn_bind PF08772.11 EGG41564.1 - 0.078 13.1 0.6 0.2 11.8 0.6 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like HTH_11 PF08279.12 EGG41564.1 - 0.082 12.9 1.5 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 HTH domain Snf7 PF03357.21 EGG41565.1 - 4.1e-06 26.5 4.8 6.8e-06 25.8 4.8 1.4 1 1 0 1 1 1 1 Snf7 TMF_DNA_bd PF12329.8 EGG41565.1 - 0.033 14.2 0.9 0.033 14.2 0.9 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RHSP PF07999.11 EGG41565.1 - 0.038 12.8 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein RVT_N PF13655.6 EGG41565.1 - 0.058 13.7 1.2 0.39 11.0 0.2 2.5 1 1 1 2 2 2 0 N-terminal domain of reverse transcriptase Baculo_PEP_C PF04513.12 EGG41565.1 - 0.068 13.2 4.6 0.87 9.6 4.6 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 EGG41565.1 - 0.15 12.1 0.5 0.15 12.1 0.5 2.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase V-ATPase_H_C PF11698.8 EGG41565.1 - 0.18 11.9 1.4 2.6 8.2 1.4 2.2 1 1 0 1 1 1 0 V-ATPase subunit H GPS2_interact PF15784.5 EGG41565.1 - 0.19 12.2 2.1 2.9 8.4 1.8 2.3 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Tropomyosin_1 PF12718.7 EGG41566.1 - 8.1e-05 22.8 18.8 0.00012 22.2 13.0 2.1 1 1 1 2 2 2 1 Tropomyosin like Spc7 PF08317.11 EGG41566.1 - 0.00015 20.8 10.1 0.00022 20.3 10.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 EGG41566.1 - 0.00069 19.7 6.8 0.0015 18.6 6.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) HMMR_N PF15905.5 EGG41566.1 - 0.00081 19.0 16.3 0.00094 18.7 15.7 1.5 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 EGG41566.1 - 0.0012 18.9 6.5 0.0019 18.2 6.5 1.4 1 0 0 1 1 1 1 Laminin Domain II DUF3450 PF11932.8 EGG41566.1 - 0.0025 17.2 2.8 0.0039 16.5 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CREPT PF16566.5 EGG41566.1 - 0.0034 17.6 5.1 0.0041 17.3 5.1 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Taxilin PF09728.9 EGG41566.1 - 0.0039 16.4 9.0 0.0039 16.4 9.0 2.0 1 1 1 2 2 2 1 Myosin-like coiled-coil protein Baculo_PEP_C PF04513.12 EGG41566.1 - 0.028 14.5 0.2 0.041 13.9 0.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 EGG41566.1 - 0.04 12.6 7.4 0.041 12.5 7.4 1.1 1 0 0 1 1 1 0 AAA domain FemAB PF02388.16 EGG41566.1 - 0.052 12.4 1.7 0.075 11.9 1.7 1.2 1 0 0 1 1 1 0 FemAB family Prefoldin PF02996.17 EGG41566.1 - 0.071 13.0 8.1 0.16 11.9 1.8 2.5 1 1 2 3 3 3 0 Prefoldin subunit Rx_N PF18052.1 EGG41566.1 - 0.11 12.8 3.3 0.19 12.0 3.3 1.5 1 0 0 1 1 1 0 Rx N-terminal domain NPV_P10 PF05531.12 EGG41566.1 - 0.13 12.7 7.0 0.7 10.4 1.7 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EGG41566.1 - 0.15 11.9 10.4 0.057 13.3 7.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Baculo_F PF12259.8 EGG41566.1 - 0.17 10.4 5.1 0.2 10.1 5.1 1.0 1 0 0 1 1 1 0 Baculovirus F protein IFT57 PF10498.9 EGG41566.1 - 0.18 10.7 10.3 0.044 12.8 7.2 1.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF16 PF01519.16 EGG41566.1 - 0.2 12.2 13.5 0.31 11.5 5.3 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 EGG41566.1 - 0.24 10.6 2.8 0.32 10.2 2.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Fmp27_WPPW PF10359.9 EGG41566.1 - 0.25 10.1 8.0 0.089 11.6 4.9 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.10 EGG41566.1 - 0.31 11.2 9.0 0.53 10.5 7.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 EGG41566.1 - 0.35 8.8 4.1 0.36 8.7 4.1 1.0 1 0 0 1 1 1 0 Prominin Spectrin PF00435.21 EGG41566.1 - 0.37 11.3 7.2 1.2 9.7 5.2 2.4 1 1 1 2 2 2 0 Spectrin repeat Mei5 PF10376.9 EGG41566.1 - 0.47 10.3 14.0 3.4 7.5 14.0 2.0 1 1 0 1 1 1 0 Double-strand recombination repair protein GldM_N PF12081.8 EGG41566.1 - 0.48 10.5 8.4 0.074 13.1 2.9 2.0 1 1 1 2 2 2 0 GldM N-terminal domain DUF948 PF06103.11 EGG41566.1 - 0.5 10.6 2.9 3.2 8.1 2.8 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 EGG41566.1 - 0.54 10.7 8.5 7.3 7.0 5.3 2.6 1 1 1 2 2 2 0 Syntaxin-like protein FlaC_arch PF05377.11 EGG41566.1 - 0.88 10.0 12.4 1.6 9.2 4.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 EGG41566.1 - 1.1 8.6 10.1 1.3 8.3 10.1 1.1 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 EGG41566.1 - 3.7 6.6 10.8 5 6.1 10.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nas2_N PF18265.1 EGG41566.1 - 5.3 7.0 8.6 5.4 7.0 0.2 3.4 1 1 1 3 3 3 0 Nas2 N_terminal domain UPF0242 PF06785.11 EGG41566.1 - 6.3 6.9 12.6 9.9 6.2 12.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HTH_45 PF14947.6 EGG41567.1 - 4.3e-10 39.4 0.0 5.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 EGG41567.1 - 1.2e-05 25.1 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EGG41567.1 - 0.00027 21.4 0.0 0.00038 20.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.6 EGG41567.1 - 0.004 16.9 0.0 0.0052 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Mrr_N PF14338.6 EGG41567.1 - 0.0041 17.2 0.0 0.037 14.2 0.0 2.0 1 1 1 2 2 2 1 Mrr N-terminal domain HTH_20 PF12840.7 EGG41567.1 - 0.012 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1495 PF07381.11 EGG41567.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) RNA_pol_Rpc34 PF05158.12 EGG41567.1 - 0.029 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit TrmB PF01978.19 EGG41567.1 - 0.042 13.7 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 EGG41567.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DDRGK PF09756.9 EGG41567.1 - 0.091 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 DDRGK domain Rrf2 PF02082.20 EGG41567.1 - 0.13 12.7 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_micro PF17007.5 EGG41568.1 - 0.00046 19.1 0.2 0.00065 18.6 0.2 1.2 1 0 0 1 1 1 1 HTH-like HTH_24 PF13412.6 EGG41568.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GlcNAc_2-epim PF07221.11 EGG41569.1 - 0.029 13.6 3.4 0.041 13.1 0.7 2.0 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) SRA1 PF07304.11 EGG41569.1 - 0.11 12.3 1.6 4 7.2 0.3 2.6 2 1 1 3 3 3 0 Steroid receptor RNA activator (SRA1) FCD PF07729.12 EGG41569.1 - 0.11 12.9 1.8 2.9 8.3 0.0 3.1 2 2 2 4 4 4 0 FCD domain Arm-DNA-bind_2 PF12167.8 EGG41569.1 - 0.14 12.1 2.6 1.3 9.0 0.0 3.3 4 0 0 4 4 4 0 Arm DNA-binding domain DUF4974 PF16344.5 EGG41569.1 - 0.33 11.0 4.8 0.18 11.8 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) UCH PF00443.29 EGG41569.1 - 3.6 7.0 15.1 4.8e+02 0.1 15.1 2.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cytochrom_B562 PF07361.11 EGG41569.1 - 8.5 7.1 28.7 0.42 11.3 2.2 4.4 1 1 3 4 4 4 0 Cytochrome b562 Ceramidase PF05875.12 EGG41570.1 - 0.042 13.3 0.0 0.05 13.0 0.0 1.0 1 0 0 1 1 1 0 Ceramidase SKG6 PF08693.10 EGG41570.1 - 0.28 10.6 0.3 0.28 10.6 0.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 EGG41570.1 - 2.8 7.7 5.7 3.1 7.6 0.6 2.0 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Saf_2TM PF18303.1 EGG41570.1 - 3.2 7.3 6.9 5.7 6.5 0.8 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Fer4_12 PF13353.6 EGG41571.1 - 2.4e-13 50.6 0.7 1.1e-12 48.4 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGG41571.1 - 1.1e-12 48.1 1.2 2.4e-12 47.0 0.2 1.9 1 1 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 EGG41571.1 - 1e-08 35.7 0.1 1.4e-08 35.3 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily GTP_cyclohydroI PF01227.22 EGG41572.1 - 1.4e-64 216.9 0.1 1.6e-64 216.7 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGG41572.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein OST-HTH PF12872.7 EGG41572.1 - 0.035 13.9 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Phage_holin_2_1 PF04971.12 EGG41573.1 - 0.059 13.4 0.4 0.059 13.4 0.4 1.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S QueC PF06508.13 EGG41574.1 - 3.1e-47 160.8 0.0 3.6e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 EGG41574.1 - 0.0004 20.1 0.0 0.00057 19.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.19 EGG41574.1 - 0.0011 18.4 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase NAD_synthase PF02540.17 EGG41574.1 - 0.0095 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 EGG41574.1 - 0.046 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 PP-loop family GHMP_kinases_N PF00288.26 EGG41575.1 - 1.6e-13 50.7 1.5 3.6e-13 49.5 1.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG41575.1 - 4.7e-07 30.1 0.0 9.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal ATP_bind_1 PF03029.17 EGG41576.1 - 2.4e-56 191.2 0.0 2.7e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EGG41576.1 - 0.0024 18.3 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 EGG41576.1 - 0.004 16.2 0.0 0.0072 15.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 EGG41576.1 - 0.0046 16.2 0.0 0.0094 15.2 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EGG41576.1 - 0.0077 16.8 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EGG41576.1 - 0.0097 15.7 0.1 0.29 10.9 0.1 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop GTP_EFTU PF00009.27 EGG41576.1 - 0.014 15.0 0.1 1 8.8 0.1 3.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 EGG41576.1 - 0.015 15.4 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 EGG41576.1 - 0.025 14.2 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EGG41576.1 - 0.065 13.3 0.1 0.88 9.7 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EGG41576.1 - 0.079 12.9 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 EGG41576.1 - 0.096 13.0 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG41576.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Imm61 PF15598.6 EGG41576.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.6 1 1 1 2 2 2 0 Immunity protein 61 LPG_synthase_TM PF03706.13 EGG41577.1 - 7e-23 81.6 15.7 9.2e-23 81.2 15.7 1.2 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region adh_short PF00106.25 EGG41578.1 - 8.3e-56 188.5 0.4 1e-55 188.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG41578.1 - 1.8e-38 132.4 0.0 2.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG41578.1 - 2.9e-15 56.6 0.3 3.8e-15 56.3 0.3 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGG41578.1 - 0.0019 17.6 0.0 0.0037 16.7 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGG41578.1 - 0.0035 16.8 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG41578.1 - 0.0077 15.4 0.1 0.0096 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420H2_quin_red PF04075.14 EGG41578.1 - 0.049 13.8 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase DFP PF04127.15 EGG41578.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Imm53 PF15580.6 EGG41579.1 - 0.063 13.0 0.2 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 Immunity protein 53 Rpr2 PF04032.16 EGG41580.1 - 0.0061 16.8 0.5 0.0074 16.6 0.2 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.12 EGG41580.1 - 0.011 15.2 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 EGG41580.1 - 0.018 15.4 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_L32p PF01783.23 EGG41580.1 - 0.036 14.3 0.4 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L32p protein family Vps36-NZF-N PF16988.5 EGG41580.1 - 0.089 12.2 0.2 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Glyco_trans_1_3 PF13528.6 EGG41581.1 - 0.046 13.0 0.0 9.4 5.4 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 1 WhiA_N PF10298.9 EGG41582.1 - 0.012 15.6 0.2 0.76 9.9 0.0 2.9 3 0 0 3 3 3 0 WhiA N-terminal LAGLIDADG-like domain PAPS_reduct PF01507.19 EGG41583.1 - 2.1e-43 148.4 0.0 2.7e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.17 EGG41584.1 - 3.4e-85 284.8 0.1 6.8e-85 283.9 0.0 1.5 2 0 0 2 2 2 1 ATP-sulfurylase PUA_2 PF14306.6 EGG41584.1 - 1.2e-46 158.3 0.0 2.5e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain PsbI PF02532.14 EGG41585.1 - 0.93 9.5 5.7 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) HhH-GPD PF00730.25 EGG41586.1 - 4.4e-26 91.4 0.1 5.5e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGG41586.1 - 7.9e-09 35.0 0.0 2.3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EGG41586.1 - 0.002 18.7 0.7 0.45 11.2 0.1 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain DUF2400 PF09674.10 EGG41586.1 - 0.0029 17.6 0.2 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2400) HHH_2 PF12826.7 EGG41586.1 - 0.012 15.7 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF521 PF04412.13 EGG41587.1 - 2.2e-109 365.8 0.0 2.6e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 EGG41588.1 - 6e-30 102.9 0.1 8.6e-30 102.4 0.1 1.2 1 0 0 1 1 1 1 Aconitase X swivel domain AMMECR1 PF01871.17 EGG41589.1 - 1.2e-51 174.7 0.0 1.3e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 TFIIE_beta PF02186.15 EGG41589.1 - 0.081 13.2 0.6 0.22 11.8 0.6 1.7 1 0 0 1 1 1 0 TFIIE beta subunit core domain Mut7-C PF01927.16 EGG41590.1 - 6.8e-39 133.3 0.4 7.7e-39 133.1 0.4 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF5615 PF18480.1 EGG41590.1 - 7.7e-05 22.4 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) PIN_10 PF18478.1 EGG41590.1 - 0.0029 17.8 0.0 0.0067 16.6 0.0 1.7 1 1 0 1 1 1 1 PIN like domain Cas6 PF09559.10 EGG41590.1 - 0.037 14.0 0.1 0.046 13.7 0.1 1.1 1 0 0 1 1 1 0 Cas6 Crispr PHP PF02811.19 EGG41590.1 - 0.04 14.2 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 PHP domain PRAI PF00697.22 EGG41590.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase FbpA PF05833.11 EGG41591.1 - 4.3e-35 121.4 6.3 5.9e-35 120.9 6.3 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EGG41591.1 - 3.7e-21 75.8 0.0 2.9e-20 72.9 0.0 2.5 3 0 0 3 3 3 1 NFACT protein RNA binding domain PKcGMP_CC PF16808.5 EGG41591.1 - 0.018 14.9 3.4 0.059 13.2 3.4 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm2_III-A PF03750.13 EGG41591.1 - 1 10.2 0.1 1 10.2 0.1 3.0 3 0 0 3 3 3 0 Csm2 Type III-A Tweety PF04906.13 EGG41591.1 - 2.3 6.8 7.5 3.3 6.3 1.6 2.2 1 1 1 2 2 2 0 Tweety DUF5379 PF17350.2 EGG41592.1 - 0.00021 21.5 3.4 0.00031 20.9 3.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5379) DUF443 PF04276.12 EGG41592.1 - 0.006 16.4 0.3 0.023 14.5 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF443) 7TM_GPCR_Srsx PF10320.9 EGG41592.1 - 0.007 15.8 4.1 0.0098 15.3 4.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RSN1_TM PF13967.6 EGG41592.1 - 0.0097 15.7 0.4 0.092 12.5 0.0 2.0 1 1 1 2 2 2 1 Late exocytosis, associated with Golgi transport DUF543 PF04418.12 EGG41592.1 - 0.054 13.5 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF543) Multi_Drug_Res PF00893.19 EGG41592.1 - 0.067 13.9 2.2 0.099 13.3 2.2 1.3 1 1 0 1 1 1 0 Small Multidrug Resistance protein Fig1 PF12351.8 EGG41592.1 - 0.089 12.7 0.9 0.74 9.7 2.4 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF202 PF02656.15 EGG41592.1 - 0.14 12.6 4.7 0.43 11.1 4.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Colicin_V PF02674.16 EGG41592.1 - 0.19 11.7 4.8 0.16 11.9 3.3 1.5 1 1 1 2 2 2 0 Colicin V production protein DUF21 PF01595.20 EGG41592.1 - 0.25 11.0 3.7 0.61 9.8 3.7 1.8 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Rab5ip PF07019.12 EGG41592.1 - 0.35 11.5 5.4 0.75 10.4 5.4 1.6 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Methyltransf_31 PF13847.6 EGG41593.1 - 1.3e-13 51.0 2.0 5.5e-13 49.0 1.1 1.9 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGG41593.1 - 2.1e-11 43.7 1.8 2.8e-11 43.4 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EGG41593.1 - 2.7e-11 43.6 0.2 3.3e-11 43.3 0.2 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EGG41593.1 - 5.5e-11 42.6 1.3 7.7e-11 42.1 1.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG41593.1 - 4.7e-10 40.0 0.1 2.3e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGG41593.1 - 3.3e-08 33.2 0.4 2.9e-07 30.1 0.2 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EGG41593.1 - 6e-08 32.4 0.3 2.2e-07 30.6 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGG41593.1 - 2.3e-07 31.3 0.0 5.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41593.1 - 3.9e-07 30.7 0.1 1.9e-06 28.5 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGG41593.1 - 1.6e-06 27.6 0.0 2.5e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 EGG41593.1 - 2.3e-06 27.4 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 EGG41593.1 - 3.8e-06 26.4 0.3 4.8e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.15 EGG41593.1 - 5.2e-06 25.9 0.2 8.5e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TrmK PF04816.12 EGG41593.1 - 1.4e-05 24.7 2.1 2e-05 24.2 2.1 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Met_10 PF02475.16 EGG41593.1 - 2.4e-05 24.2 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 EGG41593.1 - 0.00018 21.1 0.6 0.00034 20.2 0.6 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase GCD14 PF08704.10 EGG41593.1 - 0.00019 21.2 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 EGG41593.1 - 0.00041 19.9 0.1 0.0012 18.4 0.1 1.8 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.17 EGG41593.1 - 0.00044 19.5 0.1 0.00053 19.2 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.19 EGG41593.1 - 0.00081 19.5 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase TehB PF03848.14 EGG41593.1 - 0.0029 17.1 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB UPF0020 PF01170.18 EGG41593.1 - 0.0076 16.0 0.2 0.018 14.8 0.2 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EGG41593.1 - 0.018 14.7 0.2 0.79 9.4 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Methyltr_RsmB-F PF01189.17 EGG41593.1 - 0.031 13.9 0.1 0.1 12.2 0.0 1.8 1 1 0 2 2 2 0 16S rRNA methyltransferase RsmB/F CheR PF01739.18 EGG41593.1 - 0.033 13.7 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain AviRa PF11599.8 EGG41593.1 - 0.036 13.5 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_5 PF01795.19 EGG41593.1 - 0.052 13.1 0.0 0.14 11.6 0.0 1.6 1 1 1 2 2 2 0 MraW methylase family Methyltransf_23 PF13489.6 EGG41593.1 - 0.055 13.3 0.0 0.083 12.7 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EGG41593.1 - 0.066 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF3122 PF11320.8 EGG41593.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) Methyltransf_32 PF13679.6 EGG41593.1 - 0.083 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TP_methylase PF00590.20 EGG41594.1 - 7.6e-56 189.4 0.0 8.5e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.20 EGG41595.1 - 1.5e-46 159.0 0.0 1.8e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 EGG41595.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 Radical SAM superfamily UvrA_inter PF17760.1 EGG41595.1 - 0.025 14.6 0.1 0.43 10.7 0.1 2.3 2 0 0 2 2 2 0 UvrA interaction domain Aldolase PF01081.19 EGG41595.1 - 0.03 13.8 0.1 0.067 12.6 0.1 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase V-ATPase_H_N PF03224.14 EGG41595.1 - 0.035 13.4 0.6 0.078 12.3 0.1 1.8 3 0 0 3 3 3 0 V-ATPase subunit H Cyt_b-c1_8 PF10890.8 EGG41595.1 - 0.083 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 DUF2570 PF10828.8 EGG41597.1 - 0.0037 17.0 0.4 0.0043 16.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) DUF929 PF06053.11 EGG41597.1 - 0.023 14.0 3.3 0.025 13.9 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SurA_N_3 PF13624.6 EGG41597.1 - 0.1 12.4 0.5 0.11 12.3 0.5 1.1 1 0 0 1 1 1 0 SurA N-terminal domain DUF3139 PF11337.8 EGG41597.1 - 4.8 7.9 7.6 11 6.8 7.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) CBM9_1 PF06452.11 EGG41598.1 - 0.016 15.2 0.5 0.024 14.5 0.5 1.3 1 1 0 1 1 1 0 Carbohydrate family 9 binding domain-like KASH_CCD PF14662.6 EGG41600.1 - 0.0029 17.5 2.8 0.0029 17.5 2.8 1.5 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Snf7 PF03357.21 EGG41600.1 - 0.0077 15.8 6.9 0.019 14.5 6.9 1.7 1 1 0 1 1 1 1 Snf7 BLOC1S3 PF15753.5 EGG41600.1 - 0.019 15.1 0.3 0.019 15.1 0.3 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Baculo_PEP_C PF04513.12 EGG41600.1 - 0.026 14.6 2.4 0.68 10.0 0.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.10 EGG41600.1 - 0.06 13.1 0.8 0.42 10.4 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Cas_Cas7 PF05107.12 EGG41600.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 FUSC PF04632.12 EGG41600.1 - 0.15 10.5 2.1 0.18 10.3 2.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 EGG41600.1 - 0.29 11.4 4.7 8.8 6.7 1.4 3.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 EGG41600.1 - 0.43 10.8 5.1 0.077 13.2 1.2 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 EGG41600.1 - 3.3 7.4 6.5 2.1 8.0 3.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Asp_Glu_race PF01177.22 EGG41601.1 - 1e-13 51.7 0.1 1.3e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase ROK PF00480.20 EGG41601.1 - 0.068 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 ROK family Redoxin PF08534.10 EGG41601.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin Gag_p30 PF02093.16 EGG41603.1 - 0.082 12.4 0.1 11 5.4 0.0 2.1 2 0 0 2 2 2 0 Gag P30 core shell protein Cupredoxin_1 PF13473.6 EGG41604.1 - 0.00051 20.1 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 EGG41604.1 - 0.0013 19.1 1.6 0.0044 17.4 0.0 2.4 2 2 1 3 3 3 1 Copper binding proteins, plastocyanin/azurin family IF3_C PF00707.22 EGG41604.1 - 0.03 14.3 0.1 0.55 10.2 0.1 2.5 2 1 1 3 3 3 0 Translation initiation factor IF-3, C-terminal domain SGL PF08450.12 EGG41606.1 - 3.1e-15 56.4 0.1 0.00048 19.8 0.0 5.2 1 1 4 5 5 5 5 SMP-30/Gluconolactonase/LRE-like region CopD PF05425.13 EGG41606.1 - 6.9e-14 52.1 2.1 6.9e-14 52.1 2.1 2.9 3 0 0 3 3 3 1 Copper resistance protein D CopC PF04234.12 EGG41606.1 - 1e-09 39.3 0.1 2.3e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 CopC domain Reg_prop PF07494.11 EGG41606.1 - 7.3e-08 31.7 11.1 9.1 6.9 0.3 8.3 8 0 0 8 8 8 2 Two component regulator propeller YtkA PF13115.6 EGG41606.1 - 0.0017 18.9 0.3 0.01 16.4 0.0 2.3 2 1 0 2 2 2 1 YtkA-like Phytase-like PF13449.6 EGG41606.1 - 0.011 15.7 0.1 5.1 6.9 0.1 3.4 1 1 1 2 2 2 0 Esterase-like activity of phytase PPC PF04151.15 EGG41606.1 - 0.07 14.2 0.4 0.34 12.0 0.4 2.2 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain DUF4149 PF13664.6 EGG41606.1 - 1.4 9.3 9.8 0.78 10.1 2.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) ABC-3 PF00950.17 EGG41607.1 - 8.6e-64 215.5 37.2 9.6e-64 215.4 37.2 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 EGG41607.1 - 3.4e-08 32.8 33.0 3.4e-08 32.8 33.0 1.8 1 1 1 2 2 2 1 FecCD transport family DUF2953 PF11167.8 EGG41607.1 - 1 9.5 7.2 24 5.1 0.1 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF2953) ABC_tran PF00005.27 EGG41608.1 - 1.1e-36 126.4 0.1 1.1e-35 123.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGG41608.1 - 1.8e-13 51.0 0.9 7.7e-07 29.2 0.4 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG41608.1 - 1.1e-05 25.0 1.6 0.00044 19.8 1.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGG41608.1 - 0.00015 22.3 2.9 0.00035 21.1 2.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGG41608.1 - 0.0002 21.0 0.1 0.00036 20.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EGG41608.1 - 0.00053 19.8 0.3 0.65 9.7 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_27 PF13514.6 EGG41608.1 - 0.0016 18.1 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGG41608.1 - 0.0093 16.0 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG41608.1 - 0.013 15.4 0.0 0.059 13.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EGG41608.1 - 0.014 15.7 0.1 0.055 13.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 EGG41608.1 - 0.016 15.6 1.1 0.12 12.8 1.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EGG41608.1 - 0.027 14.7 0.0 1.2 9.4 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EGG41608.1 - 0.033 13.4 0.1 0.073 12.2 0.1 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 EGG41608.1 - 0.051 13.6 0.7 1.4 9.0 0.7 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG41608.1 - 0.087 13.2 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EGG41608.1 - 0.11 12.2 5.6 0.044 13.5 2.7 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EGG41608.1 - 0.19 11.4 0.0 0.87 9.2 0.0 1.7 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ZnuA PF01297.17 EGG41609.1 - 1.6e-69 234.2 0.3 1.9e-69 234.0 0.3 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF3526 PF12040.8 EGG41609.1 - 0.08 13.4 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) NikR_C PF08753.11 EGG41610.1 - 1.6e-11 44.2 2.3 2.5e-11 43.5 2.3 1.4 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 EGG41610.1 - 1.6e-06 27.8 0.1 2.7e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family VapB_antitoxin PF09957.9 EGG41610.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB DUF1327 PF07041.11 EGG41610.1 - 0.056 13.5 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) LON_substr_bdg PF02190.16 EGG41612.1 - 3.7e-10 40.0 0.1 4.4e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain OTCace_N PF02729.21 EGG41613.1 - 9.4e-41 139.3 0.0 1.4e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EGG41613.1 - 4.3e-30 104.9 0.0 6.1e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PyrI PF01948.18 EGG41614.1 - 2.8e-31 107.6 3.1 4.3e-31 107.0 3.1 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 EGG41614.1 - 1.5e-14 53.6 1.5 2.9e-14 52.7 1.5 1.5 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain SUa-2TM PF18179.1 EGG41614.1 - 0.016 14.5 0.2 0.021 14.1 0.2 1.2 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DUF1936 PF09151.10 EGG41614.1 - 0.045 13.7 0.4 0.098 12.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) ATP-synt_C PF00137.21 EGG41615.1 - 6.3e-16 58.5 16.9 6.3e-16 58.5 16.9 2.0 2 0 0 2 2 2 1 ATP synthase subunit C ATP-synt_D PF01813.17 EGG41616.1 - 2.6e-48 164.5 7.6 2.9e-48 164.3 7.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit D CLU PF13236.6 EGG41616.1 - 0.053 13.3 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria RNA_binding PF01877.17 EGG41616.1 - 0.097 13.0 6.2 1.8 8.8 0.9 2.2 2 0 0 2 2 2 0 RNA binding ATP-synt_ab PF00006.25 EGG41617.1 - 1.4e-70 237.3 0.0 1.9e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGG41617.1 - 6.5e-12 45.8 2.5 1.5e-11 44.6 2.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EGG41617.1 - 0.0003 20.9 0.5 0.0016 18.5 0.4 2.3 2 0 0 2 2 2 1 HAS barrel domain ATP-synt_ab PF00006.25 EGG41618.1 - 8.2e-93 309.9 0.0 1.1e-92 309.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGG41618.1 - 1e-38 131.9 0.0 1.7e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGG41618.1 - 5.8e-14 52.4 0.6 1.4e-13 51.1 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 EGG41618.1 - 0.028 14.7 0.2 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 EGG41618.1 - 0.11 11.0 0.2 0.18 10.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) vATP-synt_E PF01991.18 EGG41619.1 - 5.6e-19 68.3 5.0 5.6e-19 68.3 5.0 1.8 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit FliH PF02108.16 EGG41619.1 - 0.0034 17.4 0.8 0.011 15.8 0.8 2.0 1 1 0 1 1 1 1 Flagellar assembly protein FliH DUF4407 PF14362.6 EGG41619.1 - 0.021 14.2 0.6 0.032 13.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hamartin PF04388.12 EGG41619.1 - 0.083 11.6 0.6 0.088 11.5 0.6 1.0 1 0 0 1 1 1 0 Hamartin protein Imm30 PF15565.6 EGG41619.1 - 0.17 12.0 0.7 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 30 YkyA PF10368.9 EGG41619.1 - 0.38 10.4 5.9 1.5 8.5 4.9 2.0 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein V_ATPase_I PF01496.19 EGG41620.1 - 7.6e-25 87.0 11.6 2.4e-19 68.8 0.0 3.2 3 0 0 3 3 3 3 V-type ATPase 116kDa subunit family DUF1931 PF09123.11 EGG41620.1 - 0.067 13.3 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Rhodanese PF00581.20 EGG41621.1 - 4.6e-42 142.9 0.2 2.5e-21 76.2 0.0 2.0 2 0 0 2 2 2 2 Rhodanese-like domain CTP-dep_RFKase PF01982.16 EGG41621.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF120 Ammonium_transp PF00909.21 EGG41622.1 - 2e-108 362.6 33.2 2e-108 362.6 33.2 1.9 2 1 0 2 2 2 1 Ammonium Transporter Family IncF PF17626.2 EGG41622.1 - 0.03 14.7 1.0 0.11 12.9 1.0 1.9 1 0 0 1 1 1 0 Inclusion membrane protein F DUF334 PF03904.13 EGG41623.1 - 0.0097 15.5 2.2 0.014 14.9 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF334) SAM_2 PF07647.17 EGG41623.1 - 0.071 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) vATP-synt_AC39 PF01992.16 EGG41624.1 - 9.6e-52 176.5 6.3 1.2e-51 176.2 6.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Fibritin_C PF07921.12 EGG41624.1 - 0.036 14.2 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Fibritin C-terminal region Cas_Cas4 PF01930.17 EGG41626.1 - 8.9e-05 22.6 0.3 0.00013 22.1 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function DUF83 DDE_Tnp_1_6 PF13751.6 EGG41626.1 - 0.037 14.2 0.3 0.075 13.3 0.3 1.5 1 0 0 1 1 1 0 Transposase DDE domain PDDEXK_1 PF12705.7 EGG41626.1 - 0.21 11.5 1.7 3.3 7.5 1.7 2.0 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Arch_flagellin PF01917.16 EGG41627.1 - 0.0084 16.3 0.9 0.0097 16.1 0.9 1.2 1 0 0 1 1 1 1 Archaebacterial flagellin Glyco_trans_1_2 PF13524.6 EGG41628.1 - 0.037 14.4 0.0 0.054 13.9 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferases group 1 AA_kinase PF00696.28 EGG41629.1 - 1.2e-29 103.7 1.0 1.7e-29 103.1 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family HD PF01966.22 EGG41630.1 - 7e-18 65.0 0.2 1.5e-17 63.9 0.2 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EGG41630.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 HDOD domain Thymidylate_kin PF02223.17 EGG41631.1 - 3e-39 134.6 0.2 3.3e-39 134.5 0.2 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 EGG41631.1 - 0.002 18.1 2.6 0.02 14.8 2.6 2.0 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 EGG41631.1 - 0.0031 17.8 0.0 0.0041 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DnaJ_CXXCXGXG PF00684.19 EGG41632.1 - 0.0083 16.5 9.4 0.02 15.2 9.4 1.8 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGG41632.1 - 0.055 13.4 6.3 0.23 11.5 1.4 2.9 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Alfin PF12165.8 EGG41632.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Alfin DUF5351 PF17302.2 EGG41632.1 - 2.3 8.5 10.5 1.2 9.4 4.2 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5351) Rpr2 PF04032.16 EGG41632.1 - 5.9 7.2 10.1 1.9e+02 2.4 10.1 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HSP20 PF00011.21 EGG41633.1 - 9.8e-13 48.1 0.2 1.2e-12 47.8 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG41633.1 - 3.5e-08 32.9 0.1 2.6e-07 30.1 0.0 2.4 2 1 1 3 3 3 1 HSP20-like domain found in ArsA TubC_N PF18563.1 EGG41633.1 - 0.033 14.2 0.2 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 TubC N-terminal docking domain ABC1 PF03109.16 EGG41634.1 - 4.6e-23 81.6 0.0 1.7e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EGG41634.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGG41634.1 - 0.035 13.5 0.4 0.066 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein kinase domain CesT PF05932.13 EGG41634.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.6 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family Multi_Drug_Res PF00893.19 EGG41636.1 - 0.005 17.5 1.3 0.0053 17.4 1.3 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein DUF716 PF04819.12 EGG41636.1 - 0.017 14.8 0.1 0.018 14.7 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF716) DUF3611 PF12263.8 EGG41636.1 - 0.072 13.0 0.4 0.083 12.8 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) NPCBM_assoc PF10633.9 EGG41637.1 - 0.00037 20.7 1.1 0.47 10.7 0.0 3.7 3 2 1 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF11 PF01345.18 EGG41637.1 - 0.0024 18.2 4.2 0.75 10.1 1.8 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF11 DUF5385 PF17359.2 EGG41637.1 - 0.031 13.9 1.2 0.044 13.4 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4832 PF16116.5 EGG41637.1 - 0.061 13.2 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) ABC_tran PF00005.27 EGG41638.1 - 1.7e-19 70.7 0.0 2.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGG41638.1 - 8.6e-05 22.1 0.1 0.0001 21.8 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain NYN PF01936.18 EGG41638.1 - 0.015 15.7 0.4 0.052 14.0 0.4 1.7 1 1 0 1 1 1 0 NYN domain AAA_13 PF13166.6 EGG41638.1 - 0.021 13.5 0.2 0.028 13.1 0.2 1.1 1 0 0 1 1 1 0 AAA domain MacB_PCD PF12704.7 EGG41639.1 - 8.2e-19 68.7 2.0 1.4e-18 68.0 2.0 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 EGG41639.1 - 1.4e-14 54.3 2.4 1.4e-14 54.3 2.4 2.2 3 0 0 3 3 3 1 FtsX-like permease family HTH_24 PF13412.6 EGG41640.1 - 1.8e-07 30.6 1.2 4.7e-07 29.3 1.2 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EGG41640.1 - 0.00053 19.9 0.3 0.0011 18.9 0.3 1.5 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.6 EGG41640.1 - 0.00095 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Mga PF08280.11 EGG41640.1 - 0.0064 16.5 7.0 0.016 15.2 3.7 2.7 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain Trp_repressor PF01371.19 EGG41640.1 - 0.01 16.0 0.3 0.035 14.2 0.1 2.0 2 0 0 2 2 2 0 Trp repressor protein HTH_5 PF01022.20 EGG41640.1 - 0.01 15.7 0.2 0.028 14.3 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 EGG41640.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 EGG41640.1 - 0.021 14.8 0.9 0.062 13.3 0.4 2.0 2 0 0 2 2 2 0 HTH domain DUF1366 PF07104.11 EGG41640.1 - 0.029 14.1 0.3 0.065 12.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Mga PF05043.13 EGG41640.1 - 0.043 14.4 0.2 0.13 12.8 0.2 1.9 1 0 0 1 1 1 0 Mga helix-turn-helix domain PGDH_C PF16896.5 EGG41640.1 - 0.15 12.0 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term NUDIX PF00293.28 EGG41641.1 - 4.4e-18 65.6 0.0 5.5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain TetR_C_10 PF16295.5 EGG41641.1 - 0.081 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PhoU PF01895.19 EGG41642.1 - 7.1e-09 36.0 4.1 3.9e-06 27.2 1.7 2.8 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 EGG41642.1 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin GHMP_kinases_N PF00288.26 EGG41643.1 - 9.6e-11 41.8 0.1 2e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Telomere_Sde2_2 PF13297.6 EGG41643.1 - 0.018 14.6 0.2 0.086 12.5 0.1 2.1 2 0 0 2 2 2 0 Telomere stability C-terminal AnfO_nitrog PF09582.10 EGG41643.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) PPS_PS PF02006.16 EGG41644.1 - 3.1e-64 215.8 2.6 3.7e-64 215.5 2.6 1.1 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase HicB_lk_antitox PF15919.5 EGG41644.1 - 0.11 12.6 0.4 0.26 11.4 0.1 1.7 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system TPP_enzyme_M PF00205.22 EGG41644.1 - 0.13 12.0 2.4 0.23 11.2 0.5 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF3035 PF11233.8 EGG41644.1 - 0.13 12.5 0.1 0.21 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Pantoate_transf PF02548.15 EGG41645.1 - 3.4e-108 360.9 1.7 3.8e-108 360.8 1.7 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EGG41645.1 - 0.0075 15.7 0.3 0.032 13.7 0.1 1.9 1 1 2 3 3 3 2 Phosphoenolpyruvate phosphomutase DFP PF04127.15 EGG41646.1 - 4.9e-58 196.0 4.1 1.2e-55 188.3 2.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 EGG41646.1 - 8.8e-37 126.3 0.2 8.8e-37 126.3 0.2 1.9 2 1 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.6 EGG41646.1 - 0.00086 19.7 1.1 0.46 11.0 0.0 3.1 2 1 0 2 2 2 2 Putative NAD(P)-binding YjeF_N PF03853.15 EGG41646.1 - 0.0026 17.7 0.2 0.59 10.0 0.0 2.9 2 1 0 2 2 2 1 YjeF-related protein N-terminus DpaA_N PF16924.5 EGG41646.1 - 0.086 12.9 0.2 17 5.5 0.0 3.3 3 0 0 3 3 3 0 Dipicolinate synthase subunit A N-terminal domain Pyr_redox PF00070.27 EGG41646.1 - 0.12 12.9 1.7 31 5.2 0.0 4.0 4 1 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase BRCT PF00533.26 EGG41646.1 - 0.3 11.5 0.0 0.3 11.5 0.0 2.9 4 1 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain Ubie_methyltran PF01209.18 EGG41647.1 - 2.4e-18 66.3 0.1 2.5e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGG41647.1 - 2e-17 63.6 0.0 3.5e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG41647.1 - 3.2e-17 62.7 0.0 4.3e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41647.1 - 2.6e-15 56.8 0.0 5.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41647.1 - 5.2e-11 43.2 0.0 8.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG41647.1 - 6.2e-10 39.2 0.0 9.9e-10 38.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG41647.1 - 2.9e-05 23.7 0.2 5.1e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EGG41647.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 EGG41647.1 - 0.00024 20.6 0.4 0.001 18.6 0.1 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain RrnaAD PF00398.20 EGG41647.1 - 0.00041 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 EGG41647.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Fibrillarin PF01269.17 EGG41647.1 - 0.0063 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin DREV PF05219.12 EGG41647.1 - 0.0068 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 EGG41647.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 EGG41647.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 EGG41647.1 - 0.027 14.1 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PrmA PF06325.13 EGG41647.1 - 0.094 12.1 0.3 0.27 10.6 0.4 1.7 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGG41647.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M24 PF00557.24 EGG41649.1 - 6e-57 192.7 0.0 7.4e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGG41649.1 - 0.00022 21.9 0.0 0.00038 21.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sec63 PF02889.16 EGG41649.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Sec63 Brl domain DUF4428 PF14471.6 EGG41649.1 - 0.19 11.7 3.0 0.38 10.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) NFACT-R_2 PF18297.1 EGG41650.1 - 2.9e-22 78.8 0.1 5.5e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain ThiI PF02568.14 EGG41650.1 - 1.5e-12 47.5 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EGG41650.1 - 1.8e-08 33.6 0.1 3.9e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 EGG41650.1 - 0.0037 16.8 0.1 0.011 15.2 0.1 1.8 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC NFACT-R_1 PF05670.13 EGG41650.1 - 0.022 15.4 0.0 0.06 14.0 0.0 1.8 1 1 0 1 1 1 0 NFACT protein RNA binding domain Asn_synthase PF00733.21 EGG41650.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase SepF PF04472.12 EGG41651.1 - 3.1e-11 43.4 0.5 3.5e-11 43.2 0.5 1.0 1 0 0 1 1 1 1 Cell division protein SepF SporV_AA PF12164.8 EGG41651.1 - 0.023 15.0 0.7 0.034 14.5 0.7 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AA Herpes_IE68 PF02479.16 EGG41651.1 - 0.024 14.2 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus immediate early protein H_kinase_N PF12282.8 EGG41651.1 - 0.036 14.0 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal transduction histidine kinase Beta-Casp PF10996.8 EGG41652.1 - 3e-23 82.2 0.0 5.7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain KH_7 PF17214.3 EGG41652.1 - 2.3e-21 75.5 1.6 1e-20 73.4 0.8 2.5 3 0 0 3 3 3 1 KH domain RMMBL PF07521.12 EGG41652.1 - 6.7e-16 58.0 0.0 1.4e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 EGG41652.1 - 5.1e-14 52.2 0.0 9.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG41652.1 - 4.5e-12 46.4 0.7 5.1e-11 42.9 0.2 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG41652.1 - 8.3e-09 35.2 0.0 2.3e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGG41652.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Proteasome PF00227.26 EGG41653.1 - 1.3e-37 129.2 0.0 1.5e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Fe-ADH_2 PF13685.6 EGG41654.1 - 1.7e-72 244.1 1.2 1.7e-72 244.1 1.2 1.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EGG41654.1 - 1.4e-22 80.0 0.6 8.5e-22 77.5 0.6 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EGG41654.1 - 3.5e-05 23.1 0.4 0.002 17.4 0.4 2.7 1 1 0 1 1 1 1 3-dehydroquinate synthase AIRC PF00731.20 EGG41654.1 - 0.0017 17.9 3.7 0.0029 17.2 0.8 2.3 2 0 0 2 2 2 1 AIR carboxylase FKBP26_C PF18046.1 EGG41655.1 - 2.1e-12 46.9 0.9 6.5e-12 45.4 0.9 1.8 1 0 0 1 1 1 1 FKBP26_C-terminal FKBP_C PF00254.28 EGG41655.1 - 3.6e-11 43.2 0.2 2e-10 40.8 0.1 2.2 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase CAP_GLY PF01302.25 EGG41655.1 - 0.0023 17.9 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF5399 PF17377.2 EGG41655.1 - 0.18 11.6 0.2 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5399) Aminotran_5 PF00266.19 EGG41656.1 - 6.3e-38 130.7 0.0 7.8e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGG41656.1 - 3.4e-05 22.5 1.0 5.1e-05 22.0 1.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EGG41656.1 - 0.05 12.3 0.0 0.32 9.6 0.0 1.9 1 1 0 1 1 1 0 Aminotransferase class-III Lipoprotein_9 PF03180.14 EGG41656.1 - 0.055 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 NLPA lipoprotein CTP_transf_like PF01467.26 EGG41657.1 - 2.8e-12 47.0 0.0 8.3e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 EGG41657.1 - 0.05 12.8 0.1 3.3 6.8 0.0 2.3 2 1 0 2 2 2 0 HIGH Nucleotidyl Transferase RTC PF01137.21 EGG41658.1 - 2.3e-75 252.6 0.1 2.7e-75 252.4 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CopD PF05425.13 EGG41659.1 - 1.4e-15 57.6 0.3 1.4e-15 57.6 0.3 1.7 2 0 0 2 2 2 1 Copper resistance protein D UPF0093 PF03653.13 EGG41659.1 - 0.0039 17.4 8.7 0.013 15.8 8.7 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0093) 7TM_GPCR_Srv PF10323.9 EGG41659.1 - 0.0079 15.6 1.9 0.012 15.0 1.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv SieB PF14163.6 EGG41659.1 - 0.016 14.7 9.6 0.015 14.7 5.0 2.3 2 1 0 2 2 2 0 Super-infection exclusion protein B DUF4149 PF13664.6 EGG41659.1 - 0.022 15.0 2.0 0.022 15.0 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) PEMT PF04191.13 EGG41659.1 - 0.063 13.7 0.2 0.063 13.7 0.2 2.2 3 1 0 3 3 3 0 Phospholipid methyltransferase Flavi_M PF01004.19 EGG41659.1 - 0.2 11.5 2.9 0.99 9.2 0.2 2.5 1 1 1 2 2 2 0 Flavivirus envelope glycoprotein M DUF3278 PF11683.8 EGG41659.1 - 2.1 8.5 10.6 0.28 11.3 6.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DHHC PF01529.20 EGG41659.1 - 2.1 8.4 5.0 1 9.5 0.8 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Brr6_like_C_C PF10104.9 EGG41659.1 - 4 7.2 7.5 0.18 11.6 1.6 1.8 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF4878 PF12870.7 EGG41660.1 - 0.0045 17.3 0.3 0.011 16.1 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4878) Nitroreductase PF00881.24 EGG41661.1 - 1.8e-24 86.7 0.0 3.1e-24 85.9 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EGG41661.1 - 0.011 15.3 1.0 0.26 10.8 0.1 2.6 2 1 1 3 3 3 0 Putative TM nitroreductase FMN_red PF03358.15 EGG41662.1 - 5.7e-25 87.9 0.0 7.2e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGG41662.1 - 3e-08 33.6 0.0 3.7e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF2951 PF11166.8 EGG41662.1 - 0.052 13.8 0.4 0.24 11.6 0.0 2.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2951) Yuri_gagarin PF15934.5 EGG41664.1 - 0.0012 18.7 3.9 0.0014 18.5 3.9 1.1 1 0 0 1 1 1 1 Yuri gagarin DUF2730 PF10805.8 EGG41664.1 - 0.0013 18.8 7.1 0.004 17.2 1.8 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2730) MLANA PF14991.6 EGG41664.1 - 0.0051 17.1 0.3 0.0085 16.4 0.0 1.5 2 0 0 2 2 2 1 Protein melan-A ABC_membrane PF00664.23 EGG41664.1 - 0.016 14.9 0.2 0.023 14.4 0.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Vps53_N PF04100.12 EGG41664.1 - 0.024 13.6 7.5 0.029 13.4 7.5 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Troponin PF00992.20 EGG41664.1 - 0.063 13.6 6.1 0.078 13.3 6.1 1.1 1 0 0 1 1 1 0 Troponin UPF0542 PF15086.6 EGG41664.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Peptidase_U4 PF03419.13 EGG41664.1 - 0.1 11.9 2.2 0.12 11.7 0.2 1.7 2 0 0 2 2 2 0 Sporulation factor SpoIIGA FlaC_arch PF05377.11 EGG41664.1 - 0.12 12.8 6.4 1.6 9.2 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.11 EGG41664.1 - 0.21 11.1 6.7 0.25 10.8 6.7 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein FAM76 PF16046.5 EGG41664.1 - 0.25 10.6 7.5 0.35 10.2 7.5 1.3 1 0 0 1 1 1 0 FAM76 protein CheY-binding PF09078.11 EGG41664.1 - 0.3 11.2 3.4 4.6 7.4 0.2 2.9 1 1 2 3 3 3 0 CheY binding Pro_isomerase PF00160.21 EGG41665.1 - 5.7e-53 179.4 0.1 6.4e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Allantoicase PF03561.15 EGG41666.1 - 0.00038 20.5 0.1 0.001 19.0 0.0 1.7 2 0 0 2 2 2 1 Allantoicase repeat DUF5305 PF17231.2 EGG41666.1 - 0.0028 17.1 1.5 0.0037 16.7 0.4 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Glucos_trans_II PF14264.6 EGG41666.1 - 0.032 13.6 0.3 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 Glucosyl transferase GtrII DUF4366 PF14283.6 EGG41666.1 - 0.037 14.1 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 EGG41666.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF3139 PF11337.8 EGG41668.1 - 0.61 10.8 4.7 1.8 9.3 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) PfkB PF00294.24 EGG41669.1 - 1.9e-24 86.5 0.1 3.3e-24 85.7 0.1 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGG41669.1 - 3.7e-05 23.2 0.0 6.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EGG41669.1 - 0.0018 17.8 0.4 0.64 9.4 0.2 2.5 2 1 0 2 2 2 2 Carbohydrate kinase OstA_2 PF13100.6 EGG41669.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 OstA-like protein dUTPase_2 PF08761.11 EGG41670.1 - 2.1e-18 67.1 5.1 2.8e-13 50.4 0.2 2.0 1 1 1 2 2 2 2 dUTPase PRA-PH PF01503.17 EGG41670.1 - 0.00057 20.3 0.0 0.00072 20.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MtrA PF04208.14 EGG41671.1 - 4.6e-24 85.0 0.2 5.5e-24 84.7 0.2 1.0 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A DegT_DnrJ_EryC1 PF01041.17 EGG41672.1 - 2.1e-113 379.3 0.0 2.6e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGG41672.1 - 8.1e-09 34.9 0.1 1.3e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGG41672.1 - 4.2e-08 32.1 0.2 6.7e-08 31.5 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGG41672.1 - 4.2e-08 32.8 0.1 6.3e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG41672.1 - 5.3e-05 22.6 0.0 0.00016 21.0 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase ComK PF06338.11 EGG41672.1 - 0.00036 20.2 0.0 0.00088 18.9 0.0 1.6 1 0 0 1 1 1 1 ComK protein zf-C2H2 PF00096.26 EGG41675.1 - 1.1e-06 28.7 4.1 0.0056 17.1 0.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG41675.1 - 4e-06 27.2 6.2 0.031 15.1 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 EGG41675.1 - 0.0004 19.8 0.5 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EGG41675.1 - 0.0033 16.8 0.9 0.35 10.3 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EGG41675.1 - 0.0072 17.0 5.0 0.0079 16.9 5.0 1.1 1 0 0 1 1 1 1 zinc-ribbon family zf-C2H2_11 PF16622.5 EGG41675.1 - 0.017 14.9 2.1 1 9.2 0.1 2.3 1 1 1 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 EGG41675.1 - 0.03 14.3 4.1 1.2 9.1 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EGG41675.1 - 0.032 14.2 5.4 0.048 13.7 5.4 1.4 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGG41675.1 - 0.037 14.1 4.4 0.037 14.1 4.4 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF2688 PF10892.8 EGG41675.1 - 0.037 13.5 3.0 0.29 10.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) XPA_N PF01286.18 EGG41675.1 - 0.055 13.5 4.9 0.38 10.8 0.6 2.3 2 0 0 2 2 2 0 XPA protein N-terminal DUF35_N PF12172.8 EGG41675.1 - 0.059 13.3 2.8 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RNA_POL_M_15KD PF02150.16 EGG41675.1 - 0.061 13.2 5.5 1.9 8.4 5.5 2.2 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit ADK_lid PF05191.14 EGG41675.1 - 0.11 12.5 3.2 0.7 9.9 3.1 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid FYVE PF01363.21 EGG41675.1 - 0.11 12.6 6.4 0.39 10.9 1.7 2.1 1 1 1 2 2 2 0 FYVE zinc finger DUF983 PF06170.12 EGG41675.1 - 0.15 12.5 1.9 4.3 7.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf_UBZ PF18439.1 EGG41675.1 - 0.17 11.5 4.4 4.2 7.0 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Ephrin_rec_like PF07699.13 EGG41675.1 - 0.26 11.1 7.1 0.41 10.4 1.4 2.1 1 1 1 2 2 2 0 Putative ephrin-receptor like zf-ACC PF17848.1 EGG41675.1 - 0.54 10.4 0.4 0.54 10.4 0.4 3.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Fer4 PF00037.27 EGG41675.1 - 0.96 9.4 4.7 12 5.9 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain FeoC PF09012.10 EGG41676.1 - 0.0055 16.7 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 FeoC like transcriptional regulator IPPT PF01715.17 EGG41676.1 - 0.013 15.3 0.3 0.015 15.1 0.3 1.1 1 0 0 1 1 1 0 IPP transferase HTH_45 PF14947.6 EGG41676.1 - 0.051 13.6 3.6 0.13 12.2 3.6 1.9 1 1 0 1 1 1 0 Winged helix-turn-helix MarR PF01047.22 EGG41676.1 - 0.082 12.8 0.3 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 MarR family DHQ_synthase PF01761.20 EGG41677.1 - 0.015 14.5 0.1 0.018 14.2 0.1 1.0 1 0 0 1 1 1 0 3-dehydroquinate synthase ACP_PD PF04336.12 EGG41677.1 - 0.18 12.2 0.0 0.22 12.0 0.0 1.1 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase tRNA-synt_1b PF00579.25 EGG41678.1 - 1.2e-41 142.9 0.1 1.5e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Not3 PF04065.15 EGG41678.1 - 0.082 12.3 0.5 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF4092 PF13322.6 EGG41678.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) TP_methylase PF00590.20 EGG41679.1 - 2.7e-30 105.9 0.0 3.3e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases fn3_5 PF06280.12 EGG41680.1 - 0.055 14.2 0.1 2 9.1 0.0 2.8 1 1 1 2 2 2 0 Fn3-like domain Lipoprotein_15 PF03640.15 EGG41680.1 - 0.077 12.6 0.6 15 5.2 0.1 2.6 2 0 0 2 2 2 0 Secreted repeat of unknown function YabP PF07873.11 EGG41680.1 - 0.11 12.3 0.4 0.93 9.3 0.0 2.7 3 0 0 3 3 3 0 YabP family LptF_LptG PF03739.14 EGG41680.1 - 0.44 9.4 1.8 1 8.1 1.8 1.8 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG AA_kinase PF00696.28 EGG41681.1 - 3.2e-50 171.0 1.1 3.2e-50 171.0 1.1 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 EGG41681.1 - 1.3e-19 69.7 4.3 6.1e-09 35.5 0.1 2.8 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 EGG41681.1 - 1.9e-17 62.8 8.3 9e-12 44.6 0.3 2.9 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.6 EGG41681.1 - 0.035 14.1 1.7 1.2 9.2 0.1 3.2 3 0 0 3 3 3 0 ACT domain DUF4363 PF14276.6 EGG41681.1 - 0.035 14.2 1.8 0.09 12.9 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) PCNA_N PF00705.18 EGG41682.1 - 7.6e-20 70.9 0.1 1.4e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGG41682.1 - 2.7e-18 66.4 0.6 1.1e-16 61.2 0.0 2.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EGG41682.1 - 5e-07 29.0 0.1 0.012 14.6 0.0 2.2 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EGG41682.1 - 0.0051 16.3 0.0 0.0062 16.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Receptor_2B4 PF11465.8 EGG41682.1 - 0.06 13.5 0.1 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 TFIIS_C PF01096.18 EGG41683.1 - 1.1e-19 70.0 5.9 1.1e-19 70.0 5.9 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 EGG41683.1 - 0.0004 20.3 9.4 0.014 15.4 1.7 2.5 2 1 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.16 EGG41683.1 - 0.00058 19.7 15.8 0.21 11.5 5.9 3.6 2 2 1 3 3 3 2 RNA polymerases M/15 Kd subunit zinc_ribbon_4 PF13717.6 EGG41683.1 - 0.0072 16.2 15.0 0.65 10.0 0.4 4.1 3 1 0 3 3 3 1 zinc-ribbon domain Prok-RING_1 PF14446.6 EGG41683.1 - 0.025 14.5 1.3 0.025 14.5 1.3 2.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.7 EGG41683.1 - 0.08 12.9 15.3 0.076 13.0 3.2 3.4 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-RRPl_C4 PF17026.5 EGG41683.1 - 0.099 12.7 7.4 0.15 12.2 7.4 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-NADH-PPase PF09297.11 EGG41683.1 - 0.14 11.9 10.1 0.11 12.2 2.2 3.7 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Baculo_LEF5_C PF11792.8 EGG41683.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.9 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-H2C2_2 PF13465.6 EGG41683.1 - 0.25 11.9 15.5 2.3 8.8 0.6 4.0 3 1 1 4 4 4 0 Zinc-finger double domain C1_1 PF00130.22 EGG41683.1 - 0.25 11.3 9.5 0.79 9.7 1.2 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.10 EGG41683.1 - 0.3 10.8 12.9 0.91 9.3 0.2 3.9 3 1 0 4 4 4 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 EGG41683.1 - 0.35 10.9 11.7 1.5e+02 2.4 11.7 2.8 1 1 0 1 1 1 0 zinc-ribbons C1_2 PF03107.16 EGG41683.1 - 0.37 11.2 14.0 4.1 7.8 1.4 2.9 2 1 0 2 2 2 0 C1 domain zinc_ribbon_2 PF13240.6 EGG41683.1 - 0.58 9.9 15.9 13 5.6 0.1 4.0 3 1 0 3 3 3 0 zinc-ribbon domain Ribosomal_L44 PF00935.19 EGG41683.1 - 0.79 10.2 7.6 19 5.8 0.8 3.1 3 0 0 3 3 3 0 Ribosomal protein L44 DUF3795 PF12675.7 EGG41683.1 - 0.99 9.9 10.9 0.18 12.2 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) C1_4 PF07975.12 EGG41683.1 - 1.1 9.6 12.4 4.3 7.7 0.6 3.5 2 2 0 3 3 3 0 TFIIH C1-like domain IBR PF01485.21 EGG41683.1 - 1.3 9.3 12.9 4.8 7.5 2.8 3.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1 PF03811.13 EGG41683.1 - 1.7 8.4 12.1 13 5.7 3.4 3.9 3 1 0 3 3 3 0 InsA N-terminal domain HypA PF01155.19 EGG41683.1 - 2.3 8.3 12.1 3.6 7.6 2.5 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 EGG41683.1 - 2.5 8.1 12.6 0.84 9.6 1.4 3.0 1 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 EGG41683.1 - 6 6.4 17.5 33 4.1 5.9 4.1 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EGG41683.1 - 7.8 7.3 16.9 7.8e+02 0.9 16.9 2.8 1 1 0 1 1 1 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 EGG41683.1 - 7.9 6.7 15.1 8.5 6.6 0.0 4.2 3 1 1 4 4 4 0 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.19 EGG41683.1 - 8 6.9 11.3 1.6e+02 2.7 11.3 2.4 1 1 0 1 1 1 0 DnaJ central domain zf-TFIIB PF13453.6 EGG41683.1 - 8.3 5.8 15.0 5.5 6.4 3.4 3.6 2 2 1 3 3 3 0 Transcription factor zinc-finger RNA_pol_L_2 PF13656.6 EGG41684.1 - 2.3e-12 46.5 0.2 2.6e-12 46.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DSPc PF00782.20 EGG41688.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG41688.1 - 1.6e-08 34.4 0.3 6.1e-08 32.5 0.0 1.8 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGG41688.1 - 4.8e-07 30.0 0.0 7.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EGG41688.1 - 0.0016 18.2 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EGG41688.1 - 0.0069 16.4 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family UDPG_MGDP_dh_N PF03721.14 EGG41688.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GDH_N PF12466.8 EGG41688.1 - 0.045 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Rhodanese PF00581.20 EGG41688.1 - 0.08 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Rhodanese-like domain Y_phosphatase2 PF03162.13 EGG41688.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family Radical_SAM PF04055.21 EGG41689.1 - 9.2e-13 48.9 0.3 3.8e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EGG41689.1 - 0.0061 16.8 0.9 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain DUF3419 PF11899.8 EGG41689.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) zf-ribbon_3 PF13248.6 EGG41689.1 - 3.7 7.1 15.1 0.83 9.2 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-piccolo PF05715.13 EGG41689.1 - 5.6 7.2 9.9 16 5.7 0.9 3.5 3 1 1 4 4 4 0 Piccolo Zn-finger Cyclase PF04199.13 EGG41690.1 - 5.4e-32 110.9 0.0 6.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase AsnC_trans_reg PF01037.21 EGG41691.1 - 6e-08 32.5 0.1 6.4e-08 32.4 0.1 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain Aminotran_5 PF00266.19 EGG41692.1 - 9.9e-69 232.0 0.0 1.2e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGG41692.1 - 3.1e-07 29.9 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II EF-hand_1 PF00036.32 EGG41692.1 - 0.14 11.8 0.6 0.31 10.7 0.6 1.6 1 0 0 1 1 1 0 EF hand YgbB PF02542.16 EGG41692.1 - 0.15 12.3 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 YgbB family Elong_Iki1 PF10483.9 EGG41693.1 - 0.0028 17.2 0.1 0.0038 16.8 0.1 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1152 PF06626.12 EGG41693.1 - 0.021 14.1 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Alpha_L_fucos PF01120.17 EGG41693.1 - 0.026 14.0 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase Fer4 PF00037.27 EGG41694.1 - 2e-11 43.2 10.6 5.1e-07 29.3 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGG41694.1 - 6.9e-09 36.2 3.7 9.8e-09 35.7 3.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGG41694.1 - 3.5e-08 33.2 8.1 0.0013 18.7 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EGG41694.1 - 4.5e-08 33.1 1.8 6.4e-08 32.6 1.8 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG41694.1 - 4.4e-06 26.8 4.1 1.8e-05 24.8 4.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG41694.1 - 1.5e-05 24.8 7.8 0.018 15.1 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 EGG41694.1 - 7.9e-05 23.1 4.2 0.12 12.9 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 EGG41694.1 - 0.00014 21.9 8.3 0.0054 16.8 9.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EGG41694.1 - 0.00025 21.3 6.9 0.081 13.5 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EGG41694.1 - 0.00027 21.8 5.4 0.075 14.0 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 EGG41694.1 - 0.0013 19.5 11.2 0.097 13.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 EGG41694.1 - 0.0019 19.0 3.8 0.3 12.0 0.9 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG41694.1 - 0.0052 17.2 5.8 0.048 14.1 5.8 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EGG41694.1 - 0.031 14.8 6.7 1 9.9 6.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EGG41694.1 - 0.08 13.7 10.7 0.51 11.1 2.1 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 EGG41694.1 - 0.7 10.1 10.3 1.8 8.8 3.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Copper-bind PF00127.20 EGG41695.1 - 2.5e-07 31.0 0.0 5.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DUF4064 PF13273.6 EGG41695.1 - 0.085 13.1 0.4 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Cupredoxin_1 PF13473.6 EGG41695.1 - 0.095 12.8 0.0 1.1 9.4 0.0 2.9 4 1 0 4 4 4 0 Cupredoxin-like domain P-II PF00543.22 EGG41696.1 - 3.2e-18 66.2 4.6 3.8e-18 66.0 4.6 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II HAMP PF00672.25 EGG41697.1 - 8e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 HAMP domain dCache_1 PF02743.18 EGG41697.1 - 4e-12 46.5 0.2 7.9e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 Cache domain Guanylate_cyc PF00211.20 EGG41697.1 - 1.5e-10 41.0 0.1 4.1e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DnaJ PF00226.31 EGG41698.1 - 4.6e-11 42.7 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Usp PF00582.26 EGG41699.1 - 7.9e-30 104.2 0.0 9.4e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF3880 PF12996.7 EGG41699.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) CBS PF00571.28 EGG41700.1 - 3.1e-44 149.2 8.4 3.5e-12 46.6 0.1 4.1 4 0 0 4 4 4 4 CBS domain Sigma54_DBD PF04552.13 EGG41700.1 - 0.026 14.3 0.2 0.062 13.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54, DNA binding domain Ldh_1_N PF00056.23 EGG41701.1 - 1.7e-23 83.2 1.5 3.3e-23 82.3 1.5 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGG41701.1 - 2.1e-21 76.6 0.4 7.3e-21 74.8 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 EGG41701.1 - 4.9e-07 29.5 0.4 2.7e-06 27.1 0.1 2.2 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Shikimate_DH PF01488.20 EGG41701.1 - 0.0023 18.0 1.9 0.0039 17.3 0.4 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 EGG41701.1 - 0.0041 17.1 0.3 0.013 15.5 0.3 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EGG41701.1 - 0.016 15.8 0.4 0.052 14.1 0.2 2.0 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent EcoEI_R_C PF08463.10 EGG41701.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 EcoEI R protein C-terminal Sacchrp_dh_NADP PF03435.18 EGG41701.1 - 0.077 13.2 0.2 0.32 11.3 0.1 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HTH_IclR PF09339.10 EGG41702.1 - 3.7e-05 23.4 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EGG41702.1 - 0.00062 19.6 0.0 0.00087 19.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EGG41702.1 - 0.0018 18.3 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF742 PF05331.11 EGG41702.1 - 0.0081 16.0 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Hpr_kinase_N PF02603.16 EGG41702.1 - 0.0099 15.9 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 1 HPr Serine kinase N terminus FUR PF01475.19 EGG41702.1 - 0.015 15.4 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_5 PF01022.20 EGG41702.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DND1_DSRM PF14709.7 EGG41702.1 - 0.044 14.0 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF2857 PF11198.8 EGG41702.1 - 0.073 12.8 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) HTH_24 PF13412.6 EGG41702.1 - 0.08 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CBS PF00571.28 EGG41703.1 - 2.3e-44 149.6 8.5 6e-13 49.0 0.2 4.1 4 0 0 4 4 4 4 CBS domain LAMTOR5 PF16672.5 EGG41703.1 - 0.0077 16.1 0.8 0.67 9.9 0.0 3.3 4 0 0 4 4 4 1 Ragulator complex protein LAMTOR5 IF3_N PF05198.16 EGG41703.1 - 0.034 14.4 1.3 11 6.4 0.0 3.4 3 0 0 3 3 3 0 Translation initiation factor IF-3, N-terminal domain UPF0113 PF03657.13 EGG41703.1 - 0.049 13.9 4.7 9.7 6.5 0.0 4.1 3 1 0 3 3 3 0 UPF0113 PUA domain Peptidase_S7 PF00949.21 EGG41703.1 - 0.16 11.8 2.6 3.2 7.6 0.2 2.7 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease AA_permease_2 PF13520.6 EGG41704.1 - 2.2e-50 171.8 60.0 3.2e-50 171.2 60.0 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG41704.1 - 4.7e-43 147.5 53.1 6.8e-43 147.0 53.1 1.2 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 EGG41704.1 - 9.3e-07 28.0 23.8 9.3e-07 28.0 23.8 2.6 1 1 1 2 2 2 1 Spore germination protein TMEM223 PF14640.6 EGG41704.1 - 0.054 13.7 0.7 0.054 13.7 0.7 2.4 3 0 0 3 3 3 0 Transmembrane protein 223 DUF962 PF06127.11 EGG41704.1 - 0.24 11.5 3.0 2.6 8.2 0.6 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF962) Na_Ca_ex PF01699.24 EGG41705.1 - 1.3e-44 151.8 40.2 4.6e-27 94.8 16.4 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FixQ PF05545.11 EGG41705.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.6 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Usp PF00582.26 EGG41706.1 - 5.7e-27 94.9 0.2 6.6e-27 94.8 0.2 1.0 1 0 0 1 1 1 1 Universal stress protein family Pribosyltran PF00156.27 EGG41708.1 - 1.5e-19 70.0 0.3 1.5e-19 70.0 0.3 1.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EGG41708.1 - 6.2e-15 55.7 1.1 6.1e-13 49.2 0.3 2.8 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 EGG41708.1 - 9.8e-05 21.9 0.1 0.00018 21.0 0.0 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Pribosyltran_N PF13793.6 EGG41708.1 - 0.0018 18.2 0.0 0.0079 16.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase PRTase_2 PF15609.6 EGG41708.1 - 0.0023 17.4 0.1 0.0037 16.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase Asp_Glu_race PF01177.22 EGG41708.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase UPF0020 PF01170.18 EGG41709.1 - 2.7e-21 76.2 0.0 1.6e-20 73.7 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EGG41709.1 - 6.7e-13 48.9 0.0 1.3e-11 44.7 0.0 2.2 2 1 0 2 2 2 1 DNA methylase Methyltransf_31 PF13847.6 EGG41709.1 - 1.4e-09 37.9 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG41709.1 - 2.3e-08 34.6 0.0 4.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGG41709.1 - 6.8e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 EGG41709.1 - 5e-05 22.7 0.0 8.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 EGG41709.1 - 6.7e-05 23.5 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EGG41709.1 - 0.00021 20.9 0.0 0.00043 19.9 0.0 1.4 1 1 0 1 1 1 1 MraW methylase family THUMP PF02926.17 EGG41709.1 - 0.00048 20.3 0.2 0.0011 19.0 0.2 1.8 1 1 0 1 1 1 1 THUMP domain AviRa PF11599.8 EGG41709.1 - 0.00076 19.0 0.0 0.048 13.1 0.0 2.3 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_15 PF09445.10 EGG41709.1 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 EGG41709.1 - 0.0022 17.3 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGG41709.1 - 0.0025 17.3 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGG41709.1 - 0.0044 16.6 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EGG41709.1 - 0.0055 16.0 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 EGG41709.1 - 0.0079 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 EGG41709.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_12 PF08242.12 EGG41709.1 - 0.13 13.0 0.0 0.33 11.7 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Lactamase_B_2 PF12706.7 EGG41710.1 - 4.4e-16 59.0 0.0 4.5e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG41710.1 - 7.5e-08 32.6 0.0 4.4e-07 30.1 0.0 2.2 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 EGG41710.1 - 0.00033 20.3 0.0 0.00073 19.2 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease SIR2 PF02146.17 EGG41711.1 - 1.8e-53 181.1 0.0 2.3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGG41711.1 - 7.1e-05 22.6 0.0 0.054 13.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain RNA_binding PF01877.17 EGG41712.1 - 5.3e-13 49.3 0.2 2.8e-12 47.0 0.2 1.8 1 1 0 1 1 1 1 RNA binding tRNA-synt_1g PF09334.11 EGG41712.1 - 0.0019 17.0 0.1 0.0021 16.9 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) AAA_17 PF13207.6 EGG41713.1 - 1.4e-11 44.9 0.1 1.9e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG41713.1 - 3.4e-10 40.6 0.1 5.7e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG41713.1 - 0.0022 18.2 0.0 0.0038 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain UPF0180 PF03698.13 EGG41713.1 - 0.036 14.2 0.4 0.27 11.4 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) ADK PF00406.22 EGG41713.1 - 0.05 13.7 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Adenylate kinase LigT_PEase PF02834.16 EGG41714.1 - 3e-23 81.8 0.0 4.4e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 EGG41714.1 - 1.1e-12 48.3 0.2 1.5e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EGG41714.1 - 3.9e-08 33.4 0.0 4.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily tRNA_NucTransf2 PF09249.11 EGG41715.1 - 8.1e-38 129.2 0.1 1.6e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain NTP_transf_2 PF01909.23 EGG41715.1 - 1e-09 38.5 0.2 3.2e-09 37.0 0.2 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGG41715.1 - 0.00056 19.9 0.1 0.0021 18.1 0.1 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase SMODS PF18144.1 EGG41715.1 - 0.0012 19.1 1.8 0.0016 18.6 0.6 1.9 2 0 0 2 2 2 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain MCR_alpha PF02249.17 EGG41715.1 - 0.099 13.1 0.0 0.31 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Pkinase PF00069.25 EGG41716.1 - 2.1e-05 24.0 0.9 3.2e-05 23.4 0.4 1.6 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGG41716.1 - 8e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGG41716.1 - 0.00034 20.3 0.0 0.11 12.0 0.0 2.6 1 1 1 2 2 2 2 Choline/ethanolamine kinase His_Me_b4a2 PF18275.1 EGG41717.1 - 0.01 15.9 2.0 0.014 15.5 1.4 1.6 1 1 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain Pyr_redox_2 PF07992.14 EGG41718.1 - 9.6e-08 31.6 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG41719.1 - 1e-11 44.7 0.0 1.1e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG41719.1 - 0.00012 22.1 0.0 0.0055 16.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGG41719.1 - 0.00047 20.3 0.0 0.00081 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGG41719.1 - 0.00074 20.0 1.8 0.043 14.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGG41719.1 - 0.0073 15.2 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 EGG41719.1 - 0.0074 15.9 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG41719.1 - 0.018 14.3 0.3 1.8 7.7 0.0 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGG41719.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.25 EGG41720.1 - 2.4e-61 206.6 1.7 3.2e-61 206.2 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG41720.1 - 6.2e-48 163.4 1.8 7.5e-48 163.1 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG41720.1 - 4.3e-14 52.8 0.2 7.2e-14 52.1 0.1 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGG41720.1 - 0.0012 18.3 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGG41720.1 - 0.0049 16.4 0.6 0.31 10.5 0.6 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EGG41720.1 - 0.0066 15.8 3.0 0.11 11.9 0.1 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cullin PF00888.22 EGG41720.1 - 0.043 12.4 0.1 0.062 11.9 0.1 1.2 1 0 0 1 1 1 0 Cullin family BRCT_2 PF16589.5 EGG41720.1 - 0.15 12.5 0.2 0.28 11.6 0.2 1.7 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Eno-Rase_NADH_b PF12242.8 EGG41720.1 - 0.22 11.3 1.9 0.58 10.0 1.9 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.17 EGG41720.1 - 0.23 12.1 2.6 0.66 10.6 0.2 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent zf-AN1 PF01428.16 EGG41721.1 - 2.1e-11 43.8 8.2 3.2e-11 43.2 8.2 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger zf-CRD PF17979.1 EGG41721.1 - 0.044 13.9 3.0 0.053 13.6 3.0 1.3 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Transp_Tc5_C PF04236.15 EGG41721.1 - 0.047 14.1 4.1 0.089 13.2 4.1 1.5 1 1 0 1 1 1 0 Tc5 transposase C-terminal domain zf-C2H2_4 PF13894.6 EGG41721.1 - 0.5 11.4 6.0 0.71 10.9 2.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PSI_integrin PF17205.3 EGG41721.1 - 0.68 9.7 7.4 20 5.0 7.4 2.2 1 1 0 1 1 1 0 Integrin plexin domain CLN6 PF15156.6 EGG41722.1 - 0.0043 16.4 0.3 0.005 16.2 0.3 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 B12D PF06522.11 EGG41722.1 - 0.066 13.0 0.9 0.089 12.6 0.0 1.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit LptF_LptG PF03739.14 EGG41722.1 - 2.4 6.9 9.0 7.6 5.3 3.9 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Ca_bind_SSO6904 PF18249.1 EGG41723.1 - 0.00096 19.5 4.0 0.0013 19.1 1.1 2.3 1 1 1 2 2 2 1 Calcium binding protein SSO6904 Tox-PLDMTX PF15645.6 EGG41723.1 - 0.016 15.4 0.9 0.59 10.4 0.1 2.4 1 1 1 2 2 2 0 Dermonecrotoxin of the Papain-like fold RIG-I_C PF18119.1 EGG41723.1 - 0.026 14.5 1.1 0.96 9.5 0.0 2.4 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain Gln-synt_C PF00120.24 EGG41724.1 - 8.1e-115 383.5 0.0 9.3e-115 383.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGG41724.1 - 1.7e-17 62.9 0.0 4.5e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF3792 PF12670.7 EGG41725.1 - 0.089 13.0 11.4 0.099 12.8 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Cpn60_TCP1 PF00118.24 EGG41726.1 - 2.7e-184 613.4 21.4 3.1e-184 613.2 21.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dak2 PF02734.17 EGG41726.1 - 0.00014 21.8 3.0 0.0034 17.3 2.0 2.4 2 0 0 2 2 2 1 DAK2 domain Ustilago_mating PF05722.12 EGG41726.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ustilago B locus mating-type protein ADK PF00406.22 EGG41726.1 - 0.049 13.7 0.9 1.4 9.0 0.3 2.5 1 1 0 2 2 2 0 Adenylate kinase DUF2853 PF11015.8 EGG41726.1 - 0.63 10.7 4.0 0.56 10.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) SHMT PF00464.19 EGG41727.1 - 2.5e-77 260.1 0.0 3.6e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EGG41727.1 - 1.6e-07 30.9 0.0 1e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG41727.1 - 2.9e-05 23.5 0.0 9e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGG41727.1 - 0.0017 17.4 0.0 0.0033 16.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 EGG41727.1 - 0.006 15.6 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase PolC_DP2 PF03833.13 EGG41728.1 - 0 1048.8 0.0 0 1048.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 Acetyltransf_19 PF18015.1 EGG41728.1 - 0.06 13.6 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zinc-ribbons_6 PF07191.12 EGG41728.1 - 0.63 10.1 16.0 16 5.6 0.1 2.7 2 1 0 2 2 2 0 zinc-ribbons PcrB PF01884.17 EGG41729.1 - 5.2e-52 176.6 0.1 6.6e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 EGG41729.1 - 2.9e-08 33.5 0.2 2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.25 EGG41729.1 - 3.9e-08 32.7 0.1 5.1e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DpaA_N PF16924.5 EGG41729.1 - 0.0011 19.0 0.5 0.0098 16.0 0.1 2.2 2 0 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain B12-binding PF02310.19 EGG41729.1 - 0.0017 18.3 0.5 1.7 8.7 0.1 3.4 3 1 1 4 4 4 1 B12 binding domain ThiG PF05690.14 EGG41729.1 - 0.003 16.9 0.6 0.37 10.1 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.19 EGG41729.1 - 0.027 13.8 0.2 0.1 11.9 0.1 1.8 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Trp_syntA PF00290.20 EGG41729.1 - 0.029 13.2 1.0 0.14 11.0 0.2 2.2 2 1 1 3 3 3 0 Tryptophan synthase alpha chain TMP-TENI PF02581.17 EGG41729.1 - 0.042 13.2 0.1 0.57 9.5 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase Dus PF01207.17 EGG41729.1 - 0.055 12.6 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) IGPS PF00218.21 EGG41729.1 - 0.084 12.0 0.2 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DHO_dh PF01180.21 EGG41729.1 - 0.087 12.0 0.3 0.087 12.0 0.3 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EGG41729.1 - 0.14 11.6 1.5 0.29 10.5 0.1 2.2 2 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator HetR_C PF18460.1 EGG41730.1 - 0.02 14.8 0.5 0.043 13.7 0.3 1.6 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain FliH PF02108.16 EGG41730.1 - 0.042 13.9 0.2 0.11 12.5 0.0 1.7 2 1 0 2 2 2 0 Flagellar assembly protein FliH HTH_27 PF13463.6 EGG41731.1 - 4e-06 27.2 0.1 7.1e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EGG41731.1 - 0.00012 21.9 0.1 0.00028 20.7 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4364 PF14277.6 EGG41731.1 - 0.0015 18.3 0.8 0.0059 16.4 0.1 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4364) HTH_34 PF13601.6 EGG41731.1 - 0.0033 17.6 1.3 0.0053 16.9 0.3 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.22 EGG41731.1 - 0.011 15.7 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 MarR family Replic_Relax PF13814.6 EGG41731.1 - 0.011 15.8 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Replication-relaxation DUF3116 PF11313.8 EGG41731.1 - 0.014 15.2 4.1 0.019 14.8 1.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3116) HTH_45 PF14947.6 EGG41731.1 - 0.016 15.1 2.4 0.053 13.5 0.6 2.5 2 1 1 3 3 3 0 Winged helix-turn-helix DUF603 PF04645.12 EGG41731.1 - 0.046 13.4 0.3 0.079 12.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF603 DUF5376 PF17346.2 EGG41731.1 - 0.088 13.2 2.3 0.86 10.0 0.3 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5376) HTH_Crp_2 PF13545.6 EGG41731.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MazE_antitoxin PF04014.18 EGG41732.1 - 3.2e-07 30.1 0.2 3.9e-07 29.9 0.2 1.1 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin Rubredoxin_C PF18267.1 EGG41732.1 - 0.0054 16.6 0.1 0.0067 16.3 0.1 1.1 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Penicillinase_R PF03965.16 EGG41733.1 - 0.0027 18.0 0.0 0.0042 17.4 0.0 1.3 1 0 0 1 1 1 1 Penicillinase repressor Cdc6_C PF09079.11 EGG41734.1 - 9e-15 54.4 1.3 1.5e-14 53.8 0.4 1.8 2 0 0 2 2 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 EGG41734.1 - 1.2e-11 45.0 0.0 3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGG41734.1 - 1.6e-11 44.7 1.1 7.8e-11 42.5 0.3 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG41734.1 - 3.6e-08 34.0 0.0 6.5e-07 29.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EGG41734.1 - 7.7e-07 28.7 0.1 1.3e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 EGG41734.1 - 9.9e-07 28.8 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EGG41734.1 - 6.7e-06 26.2 3.1 1.8e-05 24.8 2.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EGG41734.1 - 6.9e-05 22.2 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 EGG41734.1 - 0.00027 20.2 0.1 0.00063 19.0 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase KAP_NTPase PF07693.14 EGG41734.1 - 0.0003 20.1 0.2 0.44 9.7 0.0 2.4 2 0 0 2 2 2 2 KAP family P-loop domain AAA_5 PF07728.14 EGG41734.1 - 0.00039 20.4 0.1 0.0013 18.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EGG41734.1 - 0.00065 18.9 0.0 0.0016 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EGG41734.1 - 0.00076 19.8 0.0 0.002 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGG41734.1 - 0.001 18.6 0.0 0.0029 17.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_32 PF13654.6 EGG41734.1 - 0.0014 17.5 0.4 0.2 10.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EGG41734.1 - 0.0018 17.6 0.1 0.45 9.8 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_11 PF13086.6 EGG41734.1 - 0.0034 17.2 0.3 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGG41734.1 - 0.0036 17.7 0.0 0.0096 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 EGG41734.1 - 0.0038 16.5 0.0 0.0092 15.2 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.15 EGG41734.1 - 0.0076 16.2 0.3 0.16 11.9 0.1 2.4 2 0 0 2 2 2 1 NTPase TIP49_C PF17856.1 EGG41734.1 - 0.019 15.1 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_assoc_2 PF16193.5 EGG41734.1 - 0.022 15.1 0.1 0.066 13.6 0.1 1.8 1 0 0 1 1 1 0 AAA C-terminal domain ResIII PF04851.15 EGG41734.1 - 0.024 14.6 0.2 0.44 10.5 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EGG41734.1 - 0.038 13.4 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGG41734.1 - 0.039 13.7 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGG41734.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 EGG41734.1 - 0.067 12.1 0.0 0.15 10.9 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EGG41734.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tfb5 PF06331.12 EGG41734.1 - 0.11 12.5 4.8 9.9 6.2 0.1 3.3 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 AAA_30 PF13604.6 EGG41734.1 - 0.12 12.1 0.2 0.57 9.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF512 PF04459.12 EGG41734.1 - 0.14 11.4 1.1 0.46 9.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF512) DNA_pol_E_B PF04042.16 EGG41735.1 - 8.6e-21 74.3 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 EGG41735.1 - 4.8e-13 50.1 0.0 8.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG41735.1 - 5e-08 33.3 0.0 1.4e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA_anti-codon PF01336.25 EGG41735.1 - 0.045 13.7 0.1 0.098 12.7 0.1 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF1877 PF08974.10 EGG41735.1 - 0.15 12.1 0.3 1.1 9.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) SpoIIM PF01944.17 EGG41736.1 - 1.2e-07 31.9 7.9 1.5e-07 31.6 7.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein M Copper-bind PF00127.20 EGG41737.1 - 0.052 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family TP_methylase PF00590.20 EGG41738.1 - 2.7e-35 122.2 0.0 3.1e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1944 PF09175.10 EGG41739.1 - 0.03 14.2 2.2 1.3 8.8 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1944) SpoVT_C PF15714.5 EGG41739.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor HEPN_RES_NTD1 PF18870.1 EGG41739.1 - 0.23 11.7 5.5 0.57 10.4 0.4 2.3 1 1 1 2 2 2 0 HEPN/RES N-terminal domain 1 DUF460 PF04312.13 EGG41741.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF460) RuvX PF03652.15 EGG41741.1 - 0.053 13.9 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Holliday junction resolvase DivIVA PF05103.13 EGG41742.1 - 0.00018 21.6 6.4 0.00023 21.3 6.4 1.1 1 0 0 1 1 1 1 DivIVA protein V-ATPase_G PF03179.15 EGG41742.1 - 0.0039 17.7 3.4 0.005 17.3 3.4 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 EGG41742.1 - 0.0087 16.5 6.2 0.27 11.7 0.4 2.3 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Apolipoprotein PF01442.18 EGG41742.1 - 0.015 15.2 2.4 0.02 14.7 2.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain COG6 PF06419.11 EGG41742.1 - 0.042 12.1 5.3 0.13 10.4 4.9 1.7 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 CsoSCA PF08936.10 EGG41742.1 - 0.043 12.5 0.8 0.048 12.3 0.8 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase DUF948 PF06103.11 EGG41742.1 - 0.046 14.0 3.7 0.58 10.5 3.7 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGG41742.1 - 0.051 14.0 4.6 1.2 9.6 4.6 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EGG41742.1 - 0.057 14.1 4.3 0.18 12.5 4.3 1.7 1 1 0 1 1 1 0 Initiation control protein YabA TFIIA_gamma_N PF02268.16 EGG41742.1 - 0.14 12.2 0.5 1 9.4 0.2 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain YtxH PF12732.7 EGG41742.1 - 1.1 9.8 8.8 62 4.2 8.8 2.1 1 1 0 1 1 1 0 YtxH-like protein NAC PF01849.18 EGG41743.1 - 1.5e-14 53.7 1.7 1.5e-14 53.7 1.7 1.6 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 EGG41743.1 - 0.011 15.6 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 UBA-like domain PUA PF01472.20 EGG41744.1 - 1.7e-09 37.5 0.0 4.2e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 PUA domain TGT_C2 PF14810.6 EGG41744.1 - 1.2e-07 31.8 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PhoU PF01895.19 EGG41745.1 - 1.6e-24 86.2 15.6 4.7e-17 62.2 2.6 2.4 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 EGG41745.1 - 1.1e-07 31.6 0.1 7.5e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin WAC_Acf1_DNA_bd PF10537.9 EGG41745.1 - 0.042 14.4 0.1 0.084 13.4 0.1 1.7 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF4423 PF14394.6 EGG41745.1 - 0.2 11.3 5.5 0.48 10.1 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4423) Methyltransf_25 PF13649.6 EGG41746.1 - 5.1e-19 68.8 0.0 7.4e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41746.1 - 1.8e-17 63.8 0.0 2.5e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG41746.1 - 3.7e-17 62.5 0.1 4.6e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG41746.1 - 5.4e-15 55.6 0.0 6.4e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41746.1 - 9.5e-15 55.1 0.2 1.8e-14 54.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain TPMT PF05724.11 EGG41746.1 - 1.2e-09 38.1 0.0 1.3e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 EGG41746.1 - 2.2e-08 33.8 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 EGG41746.1 - 2.4e-07 30.4 0.1 3e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EGG41746.1 - 1.1e-06 28.4 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGG41746.1 - 8.2e-06 25.3 0.0 9.6e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 EGG41746.1 - 2.2e-05 24.0 0.8 0.016 14.7 0.3 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain NodS PF05401.11 EGG41746.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 EGG41746.1 - 0.027 13.9 0.0 0.034 13.5 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Reovirus_L2 PF06016.11 EGG41746.1 - 0.031 11.5 0.0 0.038 11.2 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) tRNA_U5-meth_tr PF05958.11 EGG41746.1 - 0.046 12.7 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EGG41746.1 - 0.053 13.1 0.2 0.17 11.4 0.0 1.8 2 1 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Mur_ligase PF01225.25 EGG41746.1 - 0.069 13.5 0.0 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 Mur ligase family, catalytic domain GidB PF02527.15 EGG41746.1 - 0.12 11.7 0.0 0.77 9.1 0.0 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G GTP-bdg_N PF13167.6 EGG41747.1 - 7.3e-19 68.2 0.4 3e-18 66.3 0.1 2.3 3 0 0 3 3 1 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 EGG41747.1 - 1.2e-17 64.0 0.3 7.2e-17 61.5 0.2 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 EGG41747.1 - 9.8e-16 58.1 3.2 2.3e-15 57.0 3.2 1.7 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region FeoB_N PF02421.18 EGG41747.1 - 5.6e-09 35.7 0.3 1.1e-08 34.7 0.3 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG41747.1 - 4.5e-06 26.7 5.5 0.0034 17.3 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGG41747.1 - 0.0003 20.4 3.1 0.026 14.1 0.5 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGG41747.1 - 0.0052 16.2 1.1 0.0098 15.3 0.8 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 EGG41747.1 - 0.0077 15.8 4.3 0.86 9.2 0.2 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 EGG41747.1 - 0.0093 15.4 4.6 0.05 13.1 4.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family T2SSE PF00437.20 EGG41747.1 - 0.018 14.2 0.1 0.034 13.2 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1_Xtn PF16897.5 EGG41747.1 - 0.019 15.0 1.1 0.058 13.4 0.3 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 EGG41747.1 - 0.025 15.1 0.2 0.083 13.4 0.2 2.0 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 EGG41747.1 - 0.027 14.7 0.3 0.91 9.8 0.1 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EGG41747.1 - 0.033 13.9 6.4 0.56 10.0 5.2 3.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EGG41747.1 - 0.033 14.2 1.9 0.59 10.2 0.4 2.9 2 1 1 3 3 3 0 Dynamin family MnmE_helical PF12631.7 EGG41747.1 - 0.043 14.0 0.2 0.043 14.0 0.2 1.6 2 0 0 2 2 2 0 MnmE helical domain Remorin_C PF03763.13 EGG41747.1 - 0.078 12.9 0.1 0.078 12.9 0.1 2.6 3 0 0 3 3 3 0 Remorin, C-terminal region DUF1192 PF06698.11 EGG41747.1 - 0.091 12.8 2.3 1.2 9.2 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MobB PF03205.14 EGG41747.1 - 0.12 12.3 0.9 0.4 10.6 0.1 2.3 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Trm56 PF01994.16 EGG41748.1 - 5.5e-49 165.0 0.6 7.6e-49 164.6 0.3 1.3 2 0 0 2 2 2 1 tRNA ribose 2'-O-methyltransferase, aTrm56 SPOUT_MTase_2 PF14419.6 EGG41748.1 - 0.00056 19.3 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 AF2226-like SPOUT RNA Methylase fused to THUMP SSB PF00436.25 EGG41748.1 - 0.038 14.0 0.2 0.46 10.6 0.1 2.2 2 0 0 2 2 2 0 Single-strand binding protein family HMG_box_2 PF09011.10 EGG41748.1 - 0.047 14.3 0.2 0.098 13.3 0.2 1.4 1 0 0 1 1 1 0 HMG-box domain CsgE PF10627.9 EGG41748.1 - 0.089 13.0 0.2 30 4.9 0.0 3.1 2 2 2 4 4 4 0 Curli assembly protein CsgE Methyltransf_23 PF13489.6 EGG41748.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltrn_RNA_4 PF09936.9 EGG41748.1 - 0.13 12.1 0.1 4.5 7.1 0.0 2.2 1 1 1 2 2 2 0 SAM-dependent RNA methyltransferase DUF3085 PF11284.8 EGG41748.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) TFIIE_alpha PF02002.17 EGG41749.1 - 3.8e-15 55.6 0.8 3.8e-15 55.6 0.8 1.5 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 EGG41749.1 - 0.0042 16.6 0.8 0.0092 15.5 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.21 EGG41749.1 - 0.043 14.0 0.8 0.068 13.4 0.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Sigma70_r3 PF04539.16 EGG41749.1 - 0.058 13.5 0.3 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 TrmB PF01978.19 EGG41749.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB zf-ACC PF17848.1 EGG41749.1 - 0.063 13.4 0.7 0.26 11.4 0.2 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF3834 PF12916.7 EGG41749.1 - 0.07 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) zf-ribbon_3 PF13248.6 EGG41749.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 EGG41749.1 - 0.16 12.5 0.1 0.16 12.5 0.1 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C4_Topoisom PF01396.19 EGG41749.1 - 1.8 8.4 5.1 0.58 10.0 0.3 2.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Aldedh PF00171.22 EGG41750.1 - 5.9e-142 473.4 0.1 6.6e-142 473.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNAD3 PF18749.1 EGG41750.1 - 0.057 12.6 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Hemerythrin PF01814.23 EGG41752.1 - 3e-13 50.5 0.5 2e-12 47.9 0.1 2.3 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain Prominin PF05478.11 EGG41752.1 - 0.0021 16.1 0.9 0.0032 15.5 0.9 1.2 1 0 0 1 1 1 1 Prominin UPF0113_N PF17833.1 EGG41752.1 - 0.015 15.9 0.2 0.035 14.7 0.2 1.6 1 0 0 1 1 1 0 UPF0113 Pre-PUA domain DUF1043 PF06295.12 EGG41752.1 - 0.016 15.2 2.3 0.065 13.2 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) EDR1 PF14381.6 EGG41752.1 - 0.018 14.8 0.2 0.025 14.3 0.2 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 IZUMO PF15005.6 EGG41752.1 - 0.025 15.1 2.3 0.03 14.8 1.1 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Spore_YtfJ PF09579.10 EGG41752.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Methyltransf_4 PF02390.17 EGG41752.1 - 0.11 11.9 0.9 0.21 11.1 0.9 1.5 1 0 0 1 1 1 0 Putative methyltransferase SWIB PF02201.18 EGG41753.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain RibD_C PF01872.17 EGG41754.1 - 8.4e-52 175.9 0.1 9.4e-52 175.8 0.1 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Amidohydro_1 PF01979.20 EGG41755.1 - 3e-41 141.9 0.7 3.5e-41 141.7 0.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG41755.1 - 7.2e-16 58.7 0.0 1.4e-09 38.0 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family GCH_III PF05165.12 EGG41756.1 - 2.1e-50 171.3 0.0 3e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase III mCpol PF18182.1 EGG41756.1 - 3.4e-07 30.6 1.3 0.0021 18.4 0.2 2.2 2 0 0 2 2 2 2 minimal CRISPR polymerase domain Guanylate_cyc PF00211.20 EGG41756.1 - 0.00018 21.2 0.5 0.0004 20.0 0.2 1.8 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF3908 PF13048.6 EGG41756.1 - 0.0096 16.2 1.4 0.1 12.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3908) GGDEF_2 PF17853.1 EGG41756.1 - 0.012 15.8 0.0 5.9 7.2 0.0 2.1 2 0 0 2 2 2 0 GGDEF-like domain NOG1 PF06858.14 EGG41756.1 - 0.025 14.4 0.6 0.17 11.7 0.1 2.5 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) F420H2_quin_red PF04075.14 EGG41756.1 - 0.042 14.0 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 F420H(2)-dependent quinone reductase DMRL_synthase PF00885.19 EGG41757.1 - 2.9e-21 75.8 0.2 3.2e-21 75.6 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DHBP_synthase PF00926.19 EGG41758.1 - 1e-55 188.3 0.1 1.2e-55 188.1 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF2740 PF10872.8 EGG41758.1 - 0.44 10.5 1.7 0.46 10.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) Lum_binding PF00677.17 EGG41759.1 - 5.8e-45 151.2 4.6 1.1e-23 83.0 0.1 2.0 2 0 0 2 2 2 2 Lumazine binding domain TPR_1 PF00515.28 EGG41760.1 - 8.2e-23 79.2 8.1 4.8e-07 29.3 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG41760.1 - 2.8e-16 58.2 0.5 0.0019 18.2 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG41760.1 - 3.1e-16 59.4 0.5 1.7e-05 25.0 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG41760.1 - 2.4e-13 49.2 7.7 0.00026 21.0 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGG41760.1 - 2.1e-10 39.9 0.3 0.01 15.8 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGG41760.1 - 5.3e-09 35.7 0.1 0.035 14.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG41760.1 - 2.2e-08 34.2 0.0 2.6 9.1 0.0 5.5 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG41760.1 - 1.4e-07 32.0 0.0 0.1 13.3 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG41760.1 - 2.9e-07 30.5 0.0 0.032 14.4 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG41760.1 - 2.9e-07 30.6 6.2 0.003 17.8 0.5 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGG41760.1 - 3e-07 30.8 0.2 0.034 14.7 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGG41760.1 - 2.6e-05 24.6 0.1 5.3 7.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGG41760.1 - 2.8e-05 24.1 8.1 0.007 16.4 0.4 3.3 1 1 2 3 3 3 2 Putative TPR-like repeat TPR_17 PF13431.6 EGG41760.1 - 3.1e-05 24.0 4.7 0.96 10.0 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG41760.1 - 4.6e-05 23.0 2.6 0.012 15.3 0.3 3.9 3 1 1 4 4 4 1 TPR repeat Fis1_TPR_C PF14853.6 EGG41760.1 - 8.7e-05 22.5 4.4 2.5 8.3 0.0 4.6 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat Phage_Treg PF04761.12 EGG41760.1 - 0.00055 20.0 0.0 0.086 13.0 0.0 2.7 2 0 0 2 2 2 1 Lactococcus bacteriophage putative transcription regulator DUF3856 PF12968.7 EGG41760.1 - 0.00079 19.5 0.2 3.9 7.5 0.0 4.1 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 EGG41760.1 - 0.0017 18.9 0.3 1.3 9.4 0.2 2.6 2 1 1 3 3 3 2 Alkyl sulfatase dimerisation MIT PF04212.18 EGG41760.1 - 0.0027 17.8 2.5 0.014 15.5 0.5 2.9 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain ComX PF05952.12 EGG41760.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Bacillus competence pheromone ComX TPR_15 PF13429.6 EGG41760.1 - 0.019 14.2 0.2 0.089 12.0 0.2 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Response_reg PF00072.24 EGG41761.1 - 1.5e-20 73.4 0.1 1.8e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Viral_Hsp90 PF03225.14 EGG41761.1 - 0.0032 16.0 0.3 0.004 15.7 0.3 1.1 1 0 0 1 1 1 1 Viral heat shock protein Hsp90 homologue LisH_TPL PF17814.1 EGG41761.1 - 0.033 13.9 2.8 11 5.8 0.0 3.2 3 0 0 3 3 3 0 LisH-like dimerisation domain DUF2608 PF11019.8 EGG41761.1 - 0.049 13.1 0.6 0.069 12.6 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) RNA_pol_Rpb1_3 PF04983.18 EGG41762.1 - 1.7 8.6 8.4 1.4 8.8 1.9 2.5 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 3 HpcH_HpaI PF03328.14 EGG41763.1 - 3.3e-42 144.1 0.0 4e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EGG41763.1 - 1.3e-15 57.4 0.1 2.2e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 EGG41763.1 - 0.078 11.9 0.2 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain PINIT PF14324.6 EGG41763.1 - 0.088 13.2 1.9 3.7 7.9 0.7 2.3 2 0 0 2 2 2 0 PINIT domain Sua5_yciO_yrdC PF01300.18 EGG41764.1 - 4.5e-59 198.9 0.0 7.2e-59 198.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGG41764.1 - 1e-28 100.6 0.0 1.7e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding EF-hand_1 PF00036.32 EGG41764.1 - 0.16 11.6 1.6 0.62 9.7 0.0 2.8 4 0 0 4 4 4 0 EF hand ADH_zinc_N PF00107.26 EGG41765.1 - 7.2e-28 97.2 0.1 1.3e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG41765.1 - 2.5e-21 75.6 0.0 4.2e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGG41765.1 - 1e-17 65.5 0.1 1.7e-17 64.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 EGG41765.1 - 0.1 12.8 0.1 0.35 11.1 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal dsDNA_bind PF01984.20 EGG41766.1 - 8.2e-24 84.0 2.8 8.9e-24 83.9 2.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S19e PF01090.19 EGG41767.1 - 5.8e-48 162.1 0.0 6.5e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RuvB_C PF05491.13 EGG41767.1 - 0.12 12.2 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 RuvB C-terminal winged helix domain DUF2007 PF09413.10 EGG41767.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein ArsC PF03960.15 EGG41767.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.9 1 1 0 1 1 1 0 ArsC family Pyr_redox_2 PF07992.14 EGG41768.1 - 1.6e-34 119.5 0.0 1.9e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG41768.1 - 0.00053 20.5 1.0 0.003 18.1 1.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rpr2 PF04032.16 EGG41769.1 - 7.9e-13 48.5 1.5 1.1e-12 48.1 1.5 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Sec23_Sec24 PF04810.15 EGG41769.1 - 0.014 15.5 2.3 0.054 13.5 2.3 1.9 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger DUF3268 PF11672.8 EGG41769.1 - 0.033 14.5 0.3 0.041 14.2 0.3 1.2 1 0 0 1 1 1 0 zinc-finger-containing domain C1_1 PF00130.22 EGG41769.1 - 0.059 13.3 1.0 0.11 12.4 1.0 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2197 PF09963.9 EGG41769.1 - 0.083 13.2 2.0 1.1 9.6 0.2 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) ADK_lid PF05191.14 EGG41769.1 - 0.92 9.5 3.5 1.2 9.2 0.4 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid EMG1 PF03587.14 EGG41770.1 - 1.6e-39 135.6 0.6 1.8e-39 135.4 0.6 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_hydro_35 PF01301.19 EGG41771.1 - 0.0035 17.0 0.1 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EGG41771.1 - 0.018 14.4 0.1 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase MacB_PCD PF12704.7 EGG41771.1 - 3.4 8.0 4.9 5.9 7.2 4.9 1.7 1 1 0 1 1 1 0 MacB-like periplasmic core domain Ribonuc_red_lgC PF02867.15 EGG41772.1 - 3.1e-183 610.1 0.0 7.3e-183 608.8 0.0 1.6 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGG41772.1 - 4.6e-32 109.9 0.0 1e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGG41772.1 - 2e-21 76.3 1.7 5.6e-21 74.9 0.9 2.2 2 0 0 2 2 2 1 ATP cone domain HEPN_RES_NTD1 PF18870.1 EGG41772.1 - 0.13 12.5 0.3 9.8 6.4 0.0 3.4 3 0 0 3 3 3 0 HEPN/RES N-terminal domain 1 NRDD PF13597.6 EGG41773.1 - 2.5e-27 95.9 0.0 4.3e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_20 PF12840.7 EGG41773.1 - 4.5e-10 39.4 0.0 1.2e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-cone PF03477.16 EGG41773.1 - 1.4e-06 28.7 1.7 1.2e-05 25.8 0.0 3.4 3 2 1 4 4 4 1 ATP cone domain Lig_C PF18330.1 EGG41773.1 - 0.012 15.6 0.9 0.65 10.0 0.0 3.1 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region TackOD1 PF18551.1 EGG41773.1 - 0.09 12.4 1.8 0.1 12.3 0.2 1.9 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 OB_aCoA_assoc PF01796.17 EGG41774.1 - 5.6e-09 35.9 0.2 7.7e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 EGG41774.1 - 1.2e-06 28.2 0.3 1.8e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 EGG41774.1 - 0.00013 21.5 3.2 0.00023 20.8 3.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain TackOD1 PF18551.1 EGG41774.1 - 0.0018 18.0 0.3 0.0022 17.7 0.3 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 PHF5 PF03660.14 EGG41774.1 - 0.0048 17.1 0.2 0.0073 16.5 0.2 1.3 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.7 EGG41774.1 - 0.0089 16.0 0.3 0.014 15.4 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_10 PF10058.9 EGG41774.1 - 0.08 12.7 0.7 10 5.9 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TFIIS_C PF01096.18 EGG41774.1 - 0.17 11.8 2.3 4.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Thiolase_N PF00108.23 EGG41775.1 - 3.1e-21 75.9 0.0 1.3e-20 73.9 0.0 2.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG41775.1 - 3.9e-12 45.9 0.5 4.2e-10 39.3 0.0 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGG41775.1 - 9.4e-05 22.1 0.2 0.041 13.5 0.1 2.8 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGG41775.1 - 0.04 13.9 0.8 3.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain zf-C4_Topoisom PF01396.19 EGG41776.1 - 2.8e-07 30.2 7.9 3.6e-06 26.6 1.0 2.7 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.12 EGG41776.1 - 0.015 15.2 8.9 0.87 9.6 0.9 3.2 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Phage_HK97_TLTM PF06120.11 EGG41776.1 - 0.075 12.2 0.2 0.12 11.5 0.2 1.4 1 1 0 1 1 1 0 Tail length tape measure protein Zn_ribbon_recom PF13408.6 EGG41776.1 - 0.3 11.6 7.5 1.6 9.3 0.8 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain CN_hydrolase PF00795.22 EGG41777.1 - 1.2e-55 188.6 0.0 1.4e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Frag1 PF10277.9 EGG41777.1 - 0.088 12.3 0.8 0.13 11.8 0.8 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF1722 PF08349.11 EGG41777.1 - 0.096 13.0 0.2 0.37 11.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Tautomerase PF01361.21 EGG41778.1 - 4.8e-15 55.2 0.0 5.1e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 EGG41778.1 - 1.6e-06 28.1 0.0 1.7e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_3 PF14832.6 EGG41778.1 - 0.031 14.5 0.0 0.032 14.4 0.0 1.0 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme Rhomboid PF01694.22 EGG41779.1 - 1.1e-31 109.9 17.1 1.1e-31 109.9 17.1 1.5 2 0 0 2 2 2 1 Rhomboid family Glyco_tran_28_C PF04101.16 EGG41782.1 - 3.5e-13 49.9 0.1 2.5e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 EGG41782.1 - 1.9e-06 27.4 0.0 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.6 EGG41782.1 - 0.012 16.0 0.0 0.063 13.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 PPP5 PF08321.12 EGG41782.1 - 0.043 14.1 0.1 0.32 11.3 0.1 2.4 2 0 0 2 2 2 0 PPP5 TPR repeat region CCDC117 PF15810.5 EGG41782.1 - 0.12 12.7 0.5 0.2 11.9 0.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 AA_kinase PF00696.28 EGG41783.1 - 2e-19 70.1 0.1 3.8e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Aminotran_4 PF01063.19 EGG41785.1 - 1.3e-48 165.8 0.0 1.7e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Methyltransf_25 PF13649.6 EGG41787.1 - 6.1e-16 58.9 0.0 1.2e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG41787.1 - 1.5e-14 54.4 0.0 2.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG41787.1 - 2.9e-11 43.4 0.0 4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG41787.1 - 9.8e-08 32.0 0.0 1.4e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG41787.1 - 6.4e-07 30.0 0.0 1.2e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG41787.1 - 0.00014 21.3 0.1 0.00017 21.0 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGG41787.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.3 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EGG41787.1 - 0.0035 16.8 0.0 0.0047 16.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_L18_c PF14204.6 EGG41787.1 - 0.01 16.8 4.1 0.17 12.8 0.3 2.3 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region HATPase_c PF02518.26 EGG41788.1 - 1.5e-21 77.0 0.1 2.6e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG41788.1 - 1.1e-11 44.5 0.8 1.8e-11 43.9 0.1 1.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EGG41788.1 - 5.4e-06 26.2 1.2 6.4e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 EGG41788.1 - 0.0048 16.7 0.1 0.014 15.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAPKK1_Int PF08923.10 EGG41788.1 - 0.038 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting DUF2149 PF09919.9 EGG41788.1 - 0.7 10.2 4.2 0.49 10.7 0.4 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2149) ASC PF00858.24 EGG41788.1 - 4.3 6.2 8.4 6.9 5.5 1.1 2.9 3 0 0 3 3 3 0 Amiloride-sensitive sodium channel Response_reg PF00072.24 EGG41789.1 - 2e-24 85.9 1.1 2.4e-24 85.7 1.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HydF_dimer PF18128.1 EGG41789.1 - 0.0076 16.3 0.1 0.17 12.0 0.0 2.3 1 1 1 2 2 2 1 Hydrogen maturase F dimerization domain BRCT_3 PF18428.1 EGG41789.1 - 0.16 12.1 0.0 0.47 10.5 0.0 1.7 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain Polyketide_cyc PF03364.20 EGG41790.1 - 3.7e-06 27.2 0.0 5.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EGG41790.1 - 0.00035 20.8 0.0 0.00058 20.1 0.0 1.4 1 1 1 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EGG41790.1 - 0.0051 17.1 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PKD PF00801.20 EGG41791.1 - 0.11 12.4 0.0 5.9 6.8 0.0 2.3 1 1 1 2 2 2 0 PKD domain COX15-CtaA PF02628.15 EGG41792.1 - 1.2e-16 60.7 14.5 3e-14 52.8 8.2 2.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein FtsX PF02687.21 EGG41792.1 - 0.063 13.7 4.1 0.1 13.0 4.1 1.4 1 0 0 1 1 1 0 FtsX-like permease family SLATT_fungal PF18142.1 EGG41792.1 - 0.54 10.3 3.1 0.3 11.1 0.6 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Deltameth_res PF16020.5 EGG41792.1 - 2.9 7.8 4.9 1.8 8.5 0.3 2.4 2 1 0 2 2 2 0 Deltamethrin resistance Syndecan PF01034.20 EGG41792.1 - 5.8 6.9 7.4 0.61 10.0 2.4 1.9 2 1 0 2 2 2 0 Syndecan domain Copper-bind PF00127.20 EGG41793.1 - 1e-14 54.7 0.4 2.3e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.15 EGG41793.1 - 7.4e-11 42.1 0.8 3.1e-05 24.0 0.1 3.1 2 2 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EGG41793.1 - 3.5e-09 36.7 0.0 0.00038 20.5 0.0 2.7 2 0 0 2 2 2 2 Cupredoxin-like domain SoxE PF06525.11 EGG41793.1 - 2.5e-08 33.5 0.6 0.0083 15.6 0.0 2.7 2 1 0 2 2 2 2 Sulfocyanin (SoxE) domain Cu_bind_like PF02298.17 EGG41793.1 - 1.4e-06 28.3 0.0 0.04 13.9 0.0 2.9 2 1 0 2 2 2 2 Plastocyanin-like domain Cu-oxidase_2 PF07731.14 EGG41793.1 - 2.7e-06 27.2 0.0 0.0044 16.8 0.0 2.7 2 2 0 2 2 2 2 Multicopper oxidase DUF2475 PF10629.9 EGG41793.1 - 0.006 16.8 0.0 5.7 7.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2475) CHU_C PF13585.6 EGG41793.1 - 0.0068 16.4 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 1 C-terminal domain of CHU protein family PGBA_N PF15436.6 EGG41793.1 - 0.015 14.9 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal PPC PF04151.15 EGG41793.1 - 0.52 11.5 4.5 0.57 11.3 0.3 2.6 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain COX1 PF00115.20 EGG41794.1 - 4e-132 441.1 61.7 4.8e-132 440.9 61.7 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 EGG41795.1 - 3e-14 52.9 1.2 5.3e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 EGG41795.1 - 6e-05 23.1 0.0 7.4e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Cupredoxin-like domain DUF2391 PF09622.10 EGG41796.1 - 0.021 14.2 0.1 0.023 14.0 0.1 1.0 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) His_Phos_1 PF00300.22 EGG41797.1 - 1.1e-50 172.1 0.0 1.2e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CRM1_C PF08767.11 EGG41797.1 - 0.061 12.5 0.3 0.14 11.3 0.1 1.7 2 1 0 2 2 2 0 CRM1 C terminal F420_oxidored PF03807.17 EGG41798.1 - 6.5e-17 61.9 0.1 9.9e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EGG41798.1 - 0.0012 19.2 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGG41798.1 - 0.0051 17.1 0.0 0.0072 16.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EGG41798.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 EGG41798.1 - 0.024 14.7 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PDH PF02153.17 EGG41798.1 - 0.027 13.5 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EGG41798.1 - 0.043 13.8 0.0 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 EGG41798.1 - 0.053 13.0 0.1 0.088 12.3 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DUF5462 PF17547.2 EGG41798.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5462) YfzA PF14118.6 EGG41799.1 - 0.016 15.6 0.8 0.021 15.2 0.8 1.3 1 1 0 1 1 1 0 YfzA-like protein L6_membrane PF05805.12 EGG41799.1 - 0.021 14.4 0.3 0.025 14.1 0.3 1.0 1 0 0 1 1 1 0 L6 membrane protein Gram_pos_anchor PF00746.21 EGG41799.1 - 0.023 14.6 1.7 0.76 9.8 0.1 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF202 PF02656.15 EGG41799.1 - 0.024 15.1 1.5 0.058 13.8 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF334 PF03904.13 EGG41799.1 - 0.13 11.8 0.2 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Putative_PNPOx PF01243.20 EGG41800.1 - 1.2e-15 57.4 0.0 2.8e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EGG41800.1 - 1.4e-09 38.1 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YmdB PF13277.6 EGG41800.1 - 0.0009 18.6 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 YmdB-like protein Pyrid_ox_like PF16242.5 EGG41800.1 - 0.01 15.4 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Aminotran_1_2 PF00155.21 EGG41801.1 - 1.8e-56 191.9 0.0 2e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGG41801.1 - 3.2e-07 30.0 0.0 5.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGG41801.1 - 6.9e-06 25.3 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGG41801.1 - 0.0003 19.4 0.0 0.00041 19.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGG41801.1 - 0.09 12.0 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase EMP24_GP25L PF01105.24 EGG41802.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Invasin_D3 PF09134.10 EGG41802.1 - 0.011 16.0 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 Invasin, domain 3 Big_3 PF07523.12 EGG41802.1 - 0.063 13.6 0.1 0.26 11.6 0.2 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) SdrD_B PF17210.3 EGG41802.1 - 0.1 12.8 0.7 0.19 11.9 0.6 1.4 1 1 0 1 1 1 0 SdrD B-like domain Spore_YhaL PF14147.6 EGG41802.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1851 PF08906.11 EGG41803.1 - 0.16 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) adh_short_C2 PF13561.6 EGG41805.1 - 9.8e-19 67.8 0.0 1.2e-17 64.3 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG41805.1 - 1.4e-17 63.9 0.1 1.1e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGG41805.1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain UPF0193 PF05250.11 EGG41805.1 - 0.039 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) FeS_assembly_P PF01883.19 EGG41806.1 - 1.3e-17 63.7 0.1 2.4e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein PqqD PF05402.12 EGG41806.1 - 1.5e-10 41.2 0.1 2.6e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) HemN_C PF06969.16 EGG41806.1 - 0.013 15.5 0.5 0.025 14.6 0.5 1.4 1 0 0 1 1 1 0 HemN C-terminal domain DUF4777 PF16007.5 EGG41806.1 - 0.096 13.0 0.2 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) HTH_46 PF15977.5 EGG41806.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding IF-2B PF01008.17 EGG41807.1 - 1.9e-86 289.8 0.8 1.9e-86 289.8 0.8 1.4 2 0 0 2 2 2 1 Initiation factor 2 subunit family Putative_PNPOx PF01243.20 EGG41808.1 - 1.3e-13 51.0 0.0 3.7e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GatB_Yqey PF02637.18 EGG41808.1 - 0.012 15.5 1.3 0.012 15.5 1.3 1.5 2 0 0 2 2 2 0 GatB domain DUF2024 PF09630.10 EGG41809.1 - 6e-33 112.6 2.7 6.6e-33 112.4 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Ribonuc_red_sm PF00268.21 EGG41809.1 - 0.0041 16.6 0.2 0.0044 16.5 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CCG PF02754.16 EGG41809.1 - 0.052 13.8 0.1 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 Cysteine-rich domain Alba PF01918.21 EGG41809.1 - 0.096 12.5 0.2 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Alba CPDase PF07823.11 EGG41810.1 - 2.7e-09 37.0 2.4 1.4e-08 34.7 2.4 2.0 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EGG41810.1 - 1.9e-07 31.1 0.0 2.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EGG41810.1 - 0.0086 16.2 0.1 4.3 7.6 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase HVSL PF09749.9 EGG41810.1 - 0.01 15.3 1.7 0.034 13.6 1.7 1.9 1 1 0 1 1 1 0 Uncharacterised conserved protein ROK PF00480.20 EGG41811.1 - 9.3e-72 242.0 0.2 1.1e-71 241.8 0.2 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 EGG41811.1 - 0.0015 18.1 0.5 0.008 15.7 0.3 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.13 EGG41811.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region FGGY_N PF00370.21 EGG41811.1 - 0.032 13.8 0.0 0.096 12.2 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Cpn60_TCP1 PF00118.24 EGG41812.1 - 1.2e-177 591.5 19.3 1.4e-177 591.3 19.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Adenine_deam_C PF13382.6 EGG41813.1 - 2.5e-46 157.1 0.0 3.8e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 EGG41813.1 - 3.7e-16 59.4 0.0 3.6e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG41813.1 - 7.9e-08 32.2 0.0 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family DUF2099 PF09872.9 EGG41813.1 - 0.048 12.8 0.1 0.27 10.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) Ribosomal_L44 PF00935.19 EGG41814.1 - 3.1e-24 85.2 9.2 4.6e-24 84.7 9.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 EGG41814.1 - 0.0091 16.4 4.4 0.39 11.2 1.3 2.6 2 0 0 2 2 2 2 Ribosomal protein L33 Ribosomal_S27e PF01667.17 EGG41815.1 - 6.5e-18 64.2 1.2 7.8e-18 63.9 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 zf-ribbon_3 PF13248.6 EGG41815.1 - 0.00033 20.0 2.3 0.24 10.9 0.2 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 EGG41815.1 - 0.0014 18.6 0.5 0.0016 18.4 0.5 1.1 1 0 0 1 1 1 1 Transposase zinc-binding domain TF_Zn_Ribbon PF08271.12 EGG41815.1 - 0.0047 16.4 0.9 0.0058 16.1 0.9 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zinc_ribbon_6 PF14599.6 EGG41815.1 - 0.0076 16.2 2.7 0.04 13.9 2.9 1.9 1 1 0 1 1 1 1 Zinc-ribbon C1_1 PF00130.22 EGG41815.1 - 0.0099 15.7 0.6 0.014 15.3 0.6 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) YhfH PF14149.6 EGG41815.1 - 0.015 15.2 0.9 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-dskA_traR PF01258.17 EGG41815.1 - 0.023 14.7 0.3 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-BED PF02892.15 EGG41815.1 - 0.03 14.3 4.9 0.29 11.2 0.5 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 EGG41815.1 - 0.035 14.2 1.1 0.063 13.4 1.1 1.5 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 EGG41815.1 - 0.038 14.0 0.5 0.044 13.8 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2318 PF10080.9 EGG41815.1 - 0.044 13.9 2.4 0.056 13.6 2.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) ZZ PF00569.17 EGG41815.1 - 0.13 12.1 5.7 0.87 9.4 0.4 2.2 1 1 1 2 2 2 0 Zinc finger, ZZ type Rubredoxin_2 PF18073.1 EGG41815.1 - 0.22 11.2 3.1 6.3 6.6 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Sgf11 PF08209.11 EGG41815.1 - 0.4 10.3 4.2 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_12 PF11331.8 EGG41815.1 - 0.6 10.0 3.6 4.1 7.3 0.3 2.1 1 1 0 2 2 2 0 Probable zinc-ribbon domain TFIIS_C PF01096.18 EGG41815.1 - 0.66 9.9 3.5 38 4.2 3.5 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zf_C2H2_13 PF18508.1 EGG41815.1 - 1.7 8.3 6.3 1.6 8.4 0.6 2.4 1 1 1 2 2 2 0 Zinc finger domain zf-C2H2_3 PF13878.6 EGG41815.1 - 2.9 7.8 5.4 2.4 8.1 0.8 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO NTP_transf_3 PF12804.7 EGG41816.1 - 8.6e-13 48.9 0.0 1.1e-12 48.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGG41816.1 - 1.3e-07 31.7 0.0 1.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 EGG41816.1 - 0.00075 19.2 0.0 0.0012 18.4 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase NIF PF03031.18 EGG41816.1 - 0.022 14.5 1.9 0.45 10.3 0.5 2.3 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase CobS PF02654.15 EGG41817.1 - 9.9e-43 146.7 19.6 1.1e-42 146.5 19.6 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase RseC_MucC PF04246.12 EGG41817.1 - 0.032 14.2 1.4 0.032 14.2 1.4 3.1 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TMEM208_SND2 PF05620.11 EGG41817.1 - 2.1 8.1 4.9 0.48 10.2 0.7 1.9 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 CobD_Cbib PF03186.13 EGG41818.1 - 8.3e-85 284.3 0.0 1e-84 284.0 0.0 1.2 1 0 0 1 1 1 1 CobD/Cbib protein AAA_9 PF12781.7 EGG41818.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP-binding dynein motor region E1-E2_ATPase PF00122.20 EGG41818.1 - 1.3 8.6 6.0 0.17 11.4 1.2 1.9 2 0 0 2 2 2 0 E1-E2 ATPase AAA_26 PF13500.6 EGG41819.1 - 4.2e-07 30.0 0.0 6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGG41819.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CbiA PF01656.23 EGG41820.1 - 2.1e-12 47.2 0.1 2.2e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 EGG41820.1 - 2.2e-05 24.4 0.0 2.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 EGG41820.1 - 0.00038 20.3 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EGG41820.1 - 0.0051 17.2 0.0 0.0051 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGG41820.1 - 0.0093 16.5 0.1 0.012 16.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGG41820.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.20 EGG41820.1 - 0.041 13.8 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase CBP_BcsQ PF06564.12 EGG41820.1 - 0.042 13.3 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 EGG41820.1 - 0.058 12.7 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein PRK PF00485.18 EGG41820.1 - 0.069 12.9 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 EGG41820.1 - 0.077 12.9 0.1 0.17 11.8 0.1 1.6 1 1 1 2 2 2 0 NACHT domain DUF1533 PF07550.11 EGG41820.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) ABC_tran PF00005.27 EGG41820.1 - 0.094 13.2 0.0 0.17 12.4 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EGG41820.1 - 0.098 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGG41820.1 - 0.11 12.3 0.3 0.23 11.2 0.2 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Aminotran_1_2 PF00155.21 EGG41821.1 - 4.3e-56 190.6 0.1 5.3e-56 190.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EGG41821.1 - 0.00012 21.1 0.2 0.016 14.1 0.0 2.2 1 1 1 2 2 2 2 Allinase Aminotran_5 PF00266.19 EGG41821.1 - 0.028 13.4 0.0 0.098 11.6 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGG41821.1 - 0.05 12.1 0.0 0.091 11.3 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Semialdhyde_dhC PF02774.18 EGG41822.1 - 1.4e-35 123.1 0.0 2.1e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGG41822.1 - 1.1e-28 100.1 0.0 2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Paramyxo_PNT PF14320.6 EGG41822.1 - 0.033 13.3 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoprotein P region PNT disordered Gp_dh_C PF02800.20 EGG41822.1 - 0.058 13.0 0.6 1.1 8.9 0.2 2.5 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain PilN PF05137.13 EGG41822.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) AsnC_trans_reg PF01037.21 EGG41823.1 - 9.2e-13 48.0 0.1 1.7e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EGG41823.1 - 3.8e-09 36.0 1.8 5.9e-09 35.4 0.9 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EGG41823.1 - 2.2e-07 30.6 0.2 6e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EGG41823.1 - 6.9e-05 22.7 0.1 0.00015 21.6 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 EGG41823.1 - 0.00011 22.1 0.5 0.00022 21.1 0.2 1.7 2 0 0 2 2 2 1 HTH domain MarR_2 PF12802.7 EGG41823.1 - 0.0095 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 EGG41823.1 - 0.0099 16.0 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Rrf2 PF02082.20 EGG41823.1 - 0.063 13.6 0.2 0.51 10.7 0.1 2.2 2 1 0 2 2 2 0 Transcriptional regulator TrmB PF01978.19 EGG41823.1 - 0.07 13.0 0.4 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB FerA PF08165.11 EGG41823.1 - 0.081 12.9 0.2 3.9 7.5 0.1 2.3 2 0 0 2 2 2 0 FerA (NUC095) domain SAM_LFY PF01698.16 EGG41823.1 - 0.11 12.4 0.8 2.8 8.0 0.2 2.2 1 1 1 2 2 2 0 Floricaula / Leafy protein SAM domain UbiA PF01040.18 EGG41824.1 - 1.5e-40 139.1 20.6 1.8e-40 138.8 20.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TPR_11 PF13414.6 EGG41826.1 - 0.012 15.3 0.6 6.6 6.5 0.1 3.2 3 0 0 3 3 3 0 TPR repeat YozE_SAM_like PF06855.12 EGG41826.1 - 0.026 14.7 1.0 18 5.6 0.0 3.4 3 0 0 3 3 3 0 YozE SAM-like fold ApoLp-III PF07464.11 EGG41826.1 - 0.026 14.6 7.0 0.06 13.4 3.8 2.1 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3080 PF11279.8 EGG41826.1 - 0.036 13.3 0.4 0.036 13.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) UPF0061 PF02696.14 EGG41826.1 - 0.14 10.9 4.4 0.16 10.7 4.4 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF3106 PF11304.8 EGG41826.1 - 0.85 10.1 8.0 0.21 12.0 0.6 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF2315 PF10231.9 EGG41826.1 - 0.86 9.7 11.5 1.7 8.8 8.2 2.3 1 1 1 2 2 2 0 Apoptogenic protein 1 RPAP3_C PF13877.6 EGG41826.1 - 3.5 8.2 6.3 1.2e+02 3.4 6.3 3.0 1 1 0 1 1 1 0 Potential Monad-binding region of RPAP3 CTK3_C PF12350.8 EGG41826.1 - 3.8 7.7 7.1 27 5.0 2.3 2.7 1 1 1 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus Spore_III_AB PF09548.10 EGG41829.1 - 0.00028 21.1 6.5 0.00041 20.5 6.5 1.4 1 1 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) HBM PF16591.5 EGG41829.1 - 0.005 16.3 0.9 0.042 13.3 0.0 2.0 1 1 1 2 2 2 1 Helical bimodular sensor domain Sec5 PF15469.6 EGG41829.1 - 0.0062 16.4 1.7 0.0062 16.4 1.7 2.1 1 1 1 2 2 2 1 Exocyst complex component Sec5 RRF PF01765.19 EGG41829.1 - 0.013 15.5 1.5 0.07 13.1 0.8 2.0 1 1 1 2 2 2 0 Ribosome recycling factor DDE_Tnp_ISL3 PF01610.17 EGG41829.1 - 0.038 13.7 11.1 0.14 11.9 0.3 2.1 1 1 1 2 2 2 0 Transposase Dak2 PF02734.17 EGG41829.1 - 0.062 13.2 0.0 0.21 11.5 0.0 1.8 1 1 1 2 2 2 0 DAK2 domain HNOB PF07700.15 EGG41829.1 - 0.11 12.5 2.1 0.19 11.6 1.9 1.6 1 1 0 1 1 1 0 Haem-NO-binding DUF1722 PF08349.11 EGG41829.1 - 0.16 12.3 2.0 0.92 9.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) OmpH PF03938.14 EGG41829.1 - 0.22 11.9 8.5 0.33 11.3 4.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HU-CCDC81_bac_2 PF18175.1 EGG41829.1 - 0.24 11.3 3.4 31 4.5 0.1 3.5 2 1 2 4 4 4 0 CCDC81-like prokaryotic HU domain 2 DASH_Dad2 PF08654.10 EGG41829.1 - 0.26 11.7 9.7 4.5 7.7 0.2 2.8 1 1 2 3 3 3 0 DASH complex subunit Dad2 Sec34 PF04136.15 EGG41829.1 - 0.34 10.8 3.2 0.51 10.2 0.9 2.1 1 1 1 2 2 2 0 Sec34-like family Ribonuc_2-5A PF06479.12 EGG41829.1 - 0.48 10.6 5.3 1.2 9.3 3.9 2.2 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF745 PF05335.13 EGG41829.1 - 0.5 10.1 5.2 0.36 10.5 1.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF745) FCH PF00611.23 EGG41829.1 - 0.53 10.6 5.4 4.6 7.6 3.4 2.9 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain YtxH PF12732.7 EGG41829.1 - 0.55 10.8 2.7 4.6 7.8 2.7 2.3 1 1 0 1 1 1 0 YtxH-like protein DUF2884 PF11101.8 EGG41829.1 - 1.5 8.3 11.0 2.6 7.5 11.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) BrnA_antitoxin PF14384.6 EGG41829.1 - 1.5 9.4 5.9 23 5.6 0.7 3.4 3 1 0 3 3 3 0 BrnA antitoxin of type II toxin-antitoxin system JHBP PF06585.11 EGG41829.1 - 3.8 6.6 8.3 43 3.2 1.1 2.5 1 1 2 3 3 3 0 Haemolymph juvenile hormone binding protein (JHBP) 4HBT PF03061.22 EGG41830.1 - 8e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 EGG41830.1 - 0.00012 21.6 0.2 0.00018 21.0 0.2 1.3 1 0 0 1 1 1 1 MaoC like domain OspE PF02471.17 EGG41830.1 - 0.018 15.2 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein E UbiD PF01977.16 EGG41831.1 - 1e-92 311.1 0.1 1.1e-92 311.0 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase PGP_phosphatase PF09419.10 EGG41831.1 - 0.02 14.5 0.7 0.58 9.8 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase MID_pPIWI_RE PF18157.1 EGG41831.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 MID domain of pPIWI_RE Chlam_vir PF05475.11 EGG41832.1 - 0.015 15.1 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Pgp3 C-terminal domain PAC4 PF16093.5 EGG41832.1 - 0.021 15.0 0.3 0.028 14.6 0.3 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 FMN_red PF03358.15 EGG41837.1 - 4.9e-40 136.8 0.0 5.8e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGG41837.1 - 9.9e-10 38.4 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Pyr_redox PF00070.27 EGG41837.1 - 0.027 15.0 0.0 0.071 13.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1825 PF08855.10 EGG41838.1 - 0.02 14.8 0.8 0.54 10.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) SH3_14 PF18343.1 EGG41838.1 - 0.039 14.0 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Dda helicase SH3 domain YkyA PF10368.9 EGG41838.1 - 0.22 11.2 2.1 0.31 10.7 0.7 1.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein SF3A3 PF16837.5 EGG41838.1 - 0.32 11.5 4.5 2.5 8.7 4.0 2.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 HxlR PF01638.17 EGG41839.1 - 7.7e-26 89.8 1.8 9.2e-26 89.5 1.8 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 EGG41839.1 - 0.0028 17.8 0.2 0.004 17.3 0.2 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 EGG41839.1 - 0.011 15.7 0.2 0.023 14.6 0.2 1.5 1 0 0 1 1 1 0 MarR family PadR PF03551.14 EGG41839.1 - 0.025 14.5 0.3 0.062 13.3 0.0 1.9 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 EGG41839.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 EGG41839.1 - 0.071 13.0 1.0 0.14 12.0 0.4 1.8 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family Pirin PF02678.16 EGG41840.1 - 3.3e-36 123.5 0.3 6.3e-36 122.6 0.3 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGG41840.1 - 5.1e-34 116.8 0.1 2.7e-32 111.2 0.0 2.9 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGG41840.1 - 0.0094 15.6 3.2 0.86 9.4 0.5 2.8 3 0 0 3 3 3 2 Cupin domain zf-CDGSH PF09360.10 EGG41841.1 - 2.2e-09 37.4 1.1 3.4e-09 36.8 1.1 1.4 1 1 0 1 1 1 1 Iron-binding zinc finger CDGSH type SnoaL PF07366.12 EGG41842.1 - 5.9e-14 52.0 0.0 8.1e-14 51.5 0.0 1.2 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EGG41842.1 - 1e-06 29.3 0.0 1.6e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGG41842.1 - 0.02 15.3 0.0 0.049 14.0 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) DUF3172 PF11371.8 EGG41842.1 - 0.19 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Glyoxalase PF00903.25 EGG41843.1 - 5e-15 55.8 1.4 4e-08 33.5 0.1 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGG41843.1 - 0.0002 21.3 1.8 0.019 14.9 0.5 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_C PF14507.6 EGG41843.1 - 0.00036 21.2 1.0 0.2 12.4 0.3 2.7 2 2 0 2 2 2 2 CppA C-terminal TPR_8 PF13181.6 EGG41843.1 - 0.029 14.6 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase_4 PF13669.6 EGG41843.1 - 0.073 13.3 0.0 15 5.9 0.0 2.9 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1724 PF08350.10 EGG41844.1 - 2.6e-08 33.9 0.2 2.6e-08 33.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1724) HTH_5 PF01022.20 EGG41845.1 - 0.0027 17.5 0.1 0.0041 17.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EGG41845.1 - 0.0058 16.7 0.0 0.0074 16.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Copper-bind PF00127.20 EGG41846.1 - 0.00032 21.1 0.0 0.00082 19.8 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EGG41846.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain mTERF PF02536.14 EGG41848.1 - 0.086 11.8 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 mTERF DUF1499 PF07386.11 EGG41849.1 - 0.017 15.6 0.0 0.019 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) DUF456 PF04306.13 EGG41850.1 - 0.003 17.8 0.1 0.0039 17.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 EGG41850.1 - 1.6 8.5 9.5 4.6 7.1 9.5 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 EGG41850.1 - 1.6 8.9 6.9 2.7 8.2 6.9 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.15 EGG41850.1 - 2.2 8.2 10.2 3.9 7.4 10.2 1.4 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EGG41850.1 - 5.2 7.1 10.9 15 5.7 10.9 1.7 1 1 0 1 1 1 0 Glycine zipper DUF3810 PF12725.7 EGG41851.1 - 0.011 15.1 0.2 0.014 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TatC PF00902.18 EGG41851.1 - 0.016 15.0 2.3 0.025 14.4 2.3 1.4 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) SMP_2 PF10144.9 EGG41851.1 - 0.027 14.1 2.0 0.044 13.4 2.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin GP24_25 PF17388.2 EGG41851.1 - 0.072 13.1 0.1 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 DivIC PF04977.15 EGG41851.1 - 0.083 12.7 3.1 2.4 8.0 0.8 3.1 3 0 0 3 3 3 0 Septum formation initiator HN PF00423.19 EGG41851.1 - 1.1 7.9 4.6 1.7 7.3 4.6 1.2 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase DUF3671 PF12420.8 EGG41851.1 - 9.7 6.3 12.3 0.28 11.2 5.3 2.1 3 0 0 3 3 3 0 Protein of unknown function DUF3523 PF12037.8 EGG41852.1 - 0.58 9.5 10.4 0.69 9.2 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Ureide_permease PF07168.11 EGG41852.1 - 0.91 8.2 5.0 0.97 8.1 5.0 1.0 1 0 0 1 1 1 0 Ureide permease DUF2228 PF10228.9 EGG41852.1 - 1.2 8.8 9.0 1.5 8.5 9.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) HTH_15 PF12324.8 EGG41853.1 - 0.00033 20.6 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain of alkylmercury lyase ParBc PF02195.18 EGG41853.1 - 0.0007 19.8 0.0 0.0022 18.2 0.0 2.0 1 0 0 1 1 1 1 ParB-like nuclease domain DUF3045 PF11243.8 EGG41853.1 - 0.041 14.0 0.0 2.2 8.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3045) RuvB_C PF05491.13 EGG41853.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain HTH_40 PF14493.6 EGG41853.1 - 0.057 13.9 0.9 0.16 12.4 0.2 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain RE_TdeIII PF09520.10 EGG41854.1 - 1.9e-54 184.9 2.7 2.3e-54 184.6 2.7 1.1 1 0 0 1 1 1 1 Type II restriction endonuclease, TdeIII RE_EcoO109I PF14511.6 EGG41854.1 - 1.2e-08 34.8 1.0 0.00021 21.0 0.2 2.1 1 1 0 2 2 2 2 Type II restriction endonuclease EcoO109I N6_N4_Mtase PF01555.18 EGG41856.1 - 8.1e-20 71.5 6.3 1.8e-15 57.3 0.2 3.0 3 0 0 3 3 3 2 DNA methylase Methyltransf_15 PF09445.10 EGG41856.1 - 0.00026 20.6 0.2 0.01 15.4 0.2 2.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase HTH_17 PF12728.7 EGG41856.1 - 0.032 14.4 0.0 0.094 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4456 PF14644.6 EGG41856.1 - 0.037 13.7 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) UPF0020 PF01170.18 EGG41856.1 - 0.077 12.7 0.3 2.7 7.6 0.1 2.7 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 EGG41856.1 - 0.13 13.0 0.0 0.5 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF16 PF01519.16 EGG41856.1 - 0.86 10.1 6.0 0.41 11.2 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 PHINT_rpt PF14882.6 EGG41857.1 - 2.9e-07 30.6 16.0 0.02 15.1 0.8 3.9 3 2 0 3 3 3 3 Phage-integrase repeat unit GAD-like PF08887.11 EGG41857.1 - 2.4 8.0 7.0 14 5.5 0.3 3.1 3 0 0 3 3 3 0 GAD-like domain HxlR PF01638.17 EGG41859.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Phage_integrase PF00589.22 EGG41860.1 - 0.098 12.4 1.6 0.49 10.2 0.1 2.0 2 0 0 2 2 2 0 Phage integrase family CarboxypepD_reg PF13620.6 EGG41861.1 - 1.5e-05 25.2 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Mitofilin PF09731.9 EGG41861.1 - 0.034 13.0 5.9 0.046 12.6 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3081 PF11280.8 EGG41862.1 - 0.033 14.0 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) HSP20 PF00011.21 EGG41863.1 - 1.6e-09 37.8 0.8 3.6e-08 33.5 0.8 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG41863.1 - 2.3e-06 27.1 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 EGG41863.1 - 2.3e-06 27.9 0.0 3.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain CopG_antitoxin PF12441.8 EGG41864.1 - 0.0018 18.8 0.3 0.0085 16.6 0.1 2.1 2 1 0 2 2 2 1 CopG antitoxin of type II toxin-antitoxin system Cu-oxidase_3 PF07732.15 EGG41865.1 - 2e-25 89.1 0.4 8.5e-25 87.1 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG41865.1 - 1e-18 67.4 3.4 6.9e-06 25.8 0.0 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 EGG41865.1 - 1.1e-10 41.5 0.0 0.00011 22.3 0.0 3.4 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.20 EGG41865.1 - 4.9e-06 26.9 3.0 0.0057 17.1 0.4 3.4 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family zf-C3HC4_5 PF17121.5 EGG41866.1 - 0.0084 16.0 1.2 0.036 14.0 0.2 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 EGG41866.1 - 0.0085 15.6 0.4 3.6 7.2 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding RecR PF02132.15 EGG41866.1 - 0.033 13.8 1.2 0.061 12.9 1.2 1.5 1 1 0 1 1 1 0 RecR protein zf-C2HC5 PF06221.13 EGG41866.1 - 0.056 13.4 0.2 0.072 13.1 0.2 1.1 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-C2H2_3 PF13878.6 EGG41866.1 - 0.31 10.9 1.2 0.78 9.6 0.1 1.9 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Thioredoxin PF00085.20 EGG41867.1 - 4.4e-29 100.5 0.0 4.9e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EGG41867.1 - 4.3e-07 29.8 0.1 5.2e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGG41867.1 - 4.4e-07 30.3 0.1 1.4e-06 28.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGG41867.1 - 1.4e-06 28.6 0.1 4.2e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EGG41867.1 - 5.1e-06 26.1 0.8 1e-05 25.0 0.8 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Phosducin PF02114.16 EGG41867.1 - 0.00016 20.7 0.0 0.00018 20.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 EGG41867.1 - 0.0009 19.0 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 EGG41867.1 - 0.0014 18.8 0.3 0.0026 17.9 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EGG41867.1 - 0.0053 16.6 0.1 0.0061 16.4 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 EGG41867.1 - 0.0067 16.3 0.0 0.0076 16.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 EGG41867.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EGG41867.1 - 0.088 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GTP_EFTU PF00009.27 EGG41868.1 - 6.1e-32 110.7 0.0 1.4e-31 109.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 EGG41868.1 - 3.2e-22 78.2 0.2 1.2e-21 76.4 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 IF-2 PF11987.8 EGG41868.1 - 9.9e-22 77.1 0.6 3e-21 75.5 0.6 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGG41868.1 - 1.6e-08 34.6 0.5 4.6e-07 29.9 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EGG41868.1 - 5.2e-05 23.4 0.0 0.00018 21.7 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 EGG41868.1 - 8.4e-05 22.9 0.5 0.00058 20.2 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 EGG41868.1 - 0.00012 21.9 0.0 0.00046 20.1 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EGG41868.1 - 0.0019 18.3 0.3 0.16 12.0 0.0 2.8 1 1 0 2 2 2 1 Dynamin family Ras PF00071.22 EGG41868.1 - 0.0026 17.4 0.1 0.038 13.6 0.0 2.6 2 1 0 2 2 2 1 Ras family cobW PF02492.19 EGG41868.1 - 0.032 13.8 1.3 1.3 8.6 0.0 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF4473 PF14747.6 EGG41868.1 - 0.17 12.4 0.6 17 6.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) NDK PF00334.19 EGG41869.1 - 3e-32 111.5 0.0 3.3e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ribosomal_L24e PF01246.20 EGG41870.1 - 1.3e-18 67.0 1.0 1.3e-18 67.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FLZ PF04570.14 EGG41870.1 - 0.014 14.9 0.2 0.023 14.2 0.2 1.4 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 EGG41870.1 - 0.065 13.4 6.0 5.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Ribosomal_S28e PF01200.18 EGG41871.1 - 2.8e-27 94.5 4.4 3e-27 94.4 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L7Ae PF01248.26 EGG41872.1 - 7.2e-26 89.8 0.1 8.8e-26 89.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EGG41872.1 - 0.0013 18.6 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain PGM_PMM_I PF02878.16 EGG41873.1 - 1.1e-36 125.6 0.0 1.9e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGG41873.1 - 1.1e-24 87.0 0.0 2.3e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGG41873.1 - 7.7e-23 80.9 0.0 1.4e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EGG41873.1 - 1.5e-08 34.7 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Formyl_trans_N PF00551.19 EGG41874.1 - 2.3e-45 154.6 0.1 3.2e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 EGG41874.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 EGG41874.1 - 0.0062 16.3 0.2 0.031 14.0 0.1 2.3 2 1 0 2 2 2 1 ACT domain ACT_4 PF13291.6 EGG41874.1 - 0.031 14.9 1.4 0.09 13.4 0.1 2.5 1 1 2 3 3 3 0 ACT domain Creatininase PF02633.14 EGG41875.1 - 8.4e-50 169.5 0.0 1.1e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase HflK_N PF12221.8 EGG41875.1 - 0.17 11.9 0.1 0.65 10.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial membrane protein N terminal LSM PF01423.22 EGG41876.1 - 1.2e-23 82.5 0.6 1.4e-23 82.4 0.6 1.0 1 0 0 1 1 1 1 LSM domain MTS_N PF08468.11 EGG41877.1 - 0.0041 17.2 0.1 0.0086 16.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain N-terminal Flagellin_C PF00700.21 EGG41877.1 - 0.034 14.5 0.3 0.33 11.3 0.2 2.6 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Rib_5-P_isom_A PF06026.14 EGG41878.1 - 1.4e-53 181.1 0.1 1.6e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EGG41878.1 - 0.0029 17.6 0.2 0.25 11.3 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Cupredoxin_1 PF13473.6 EGG41879.1 - 6e-08 32.7 0.0 8.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Staphopain_pro PF14731.6 EGG41879.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Staphopain proregion AIF-MLS PF14962.6 EGG41879.1 - 0.71 9.8 1.9 0.8 9.6 0.4 1.7 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Amidohydro_1 PF01979.20 EGG41880.1 - 5.6e-21 75.2 0.4 1.9e-20 73.5 0.4 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG41880.1 - 5.5e-15 55.8 0.1 2.5e-09 37.2 0.0 3.2 2 1 1 3 3 3 3 Amidohydrolase family TatD_DNase PF01026.21 EGG41880.1 - 0.00097 18.6 0.0 0.0039 16.6 0.0 1.8 2 1 0 2 2 2 1 TatD related DNase Hom_end PF05204.14 EGG41880.1 - 0.073 13.2 0.0 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Homing endonuclease zinc_ribbon_2 PF13240.6 EGG41881.1 - 1.8e-08 33.8 4.4 3.4e-08 32.9 4.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGG41881.1 - 1.9e-06 27.0 2.1 3.1e-06 26.4 2.1 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGG41881.1 - 5.2e-06 26.4 1.5 9e-06 25.6 1.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGG41881.1 - 7.5e-05 23.4 0.2 9.6e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 EGG41881.1 - 0.00021 21.3 4.0 0.00052 20.0 3.9 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 EGG41881.1 - 0.0057 16.6 8.8 0.11 12.4 0.3 2.6 3 0 0 3 3 2 2 Nudix N-terminal A2L_zn_ribbon PF08792.10 EGG41881.1 - 0.012 15.4 1.4 2.1 8.2 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain RNA_POL_M_15KD PF02150.16 EGG41881.1 - 0.033 14.0 3.6 2.9 7.9 0.5 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C3HC4_3 PF13920.6 EGG41881.1 - 0.052 13.4 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NADH-PPase PF09297.11 EGG41881.1 - 0.062 13.0 5.7 1.2 8.9 0.4 2.2 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Prok-RING_1 PF14446.6 EGG41881.1 - 0.074 13.0 2.1 0.12 12.3 2.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 NRDD PF13597.6 EGG41881.1 - 0.1 11.4 0.6 0.12 11.1 0.6 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase HypA PF01155.19 EGG41881.1 - 0.1 12.6 0.9 0.15 12.1 0.9 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 EGG41881.1 - 0.13 11.9 3.7 1.5 8.5 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger GFA PF04828.14 EGG41881.1 - 0.18 12.2 3.7 10 6.5 3.7 2.3 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme ADK_lid PF05191.14 EGG41881.1 - 0.2 11.7 2.4 2 8.4 0.1 2.2 1 1 1 2 2 2 0 Adenylate kinase, active site lid RecR PF02132.15 EGG41881.1 - 0.27 10.9 1.9 7 6.3 0.1 2.1 1 1 1 2 2 2 0 RecR protein NOB1_Zn_bind PF08772.11 EGG41881.1 - 0.3 11.3 6.5 3.6 7.8 6.7 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like YhfH PF14149.6 EGG41881.1 - 0.74 9.8 4.8 12 6.0 0.2 2.3 1 1 1 2 2 2 0 YhfH-like protein zf-tcix PF14952.6 EGG41881.1 - 1 9.0 5.9 3.8 7.2 0.8 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding LisH_2 PF16045.5 EGG41881.1 - 3.4 6.8 8.1 5.3 6.2 0.7 2.9 3 0 0 3 3 3 0 LisH HscB_4_cys PF18256.1 EGG41881.1 - 5.5 6.9 6.7 7.8 6.4 0.6 2.2 1 1 1 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zinc_ribbon_2 PF13240.6 EGG41882.1 - 2e-06 27.3 3.2 3.1e-06 26.7 3.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGG41882.1 - 0.00017 21.5 0.5 0.00025 21.0 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGG41882.1 - 0.0038 18.0 0.2 0.0092 16.7 0.1 1.7 2 0 0 2 2 2 1 zinc-ribbon family UPF0547 PF10571.9 EGG41882.1 - 0.0042 17.1 0.4 0.0063 16.6 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 EGG41882.1 - 0.033 13.6 2.4 0.069 12.6 2.4 1.6 1 1 0 1 1 1 0 zinc-ribbon domain YkyA PF10368.9 EGG41882.1 - 0.16 11.6 0.7 0.21 11.3 0.7 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Nudix_N_2 PF14803.6 EGG41882.1 - 0.7 9.9 6.1 2.1 8.3 1.4 2.2 2 0 0 2 2 2 0 Nudix N-terminal YhfH PF14149.6 EGG41882.1 - 4 7.5 6.4 2.7 8.0 0.5 2.9 2 1 1 3 3 3 0 YhfH-like protein Thioredoxin PF00085.20 EGG41883.1 - 7.2e-31 106.2 0.1 8.2e-31 106.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG41883.1 - 3.7e-11 43.2 0.2 1.1e-06 28.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGG41883.1 - 2e-08 34.6 0.1 8.1e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGG41883.1 - 3.2e-06 27.2 0.1 5.1e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EGG41883.1 - 4e-06 26.8 0.1 4.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 EGG41883.1 - 4.8e-06 26.4 0.1 5.7e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGG41883.1 - 5.3e-05 23.1 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 EGG41883.1 - 0.00021 21.2 0.0 0.00025 21.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EGG41883.1 - 0.00034 20.1 0.0 0.00034 20.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGG41883.1 - 0.00036 20.2 0.2 0.00075 19.2 0.2 1.5 1 1 0 1 1 1 1 Redoxin HyaE PF07449.11 EGG41883.1 - 0.001 19.0 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 EGG41883.1 - 0.004 16.8 0.2 0.01 15.4 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_6 PF13848.6 EGG41883.1 - 0.0061 16.5 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EGG41883.1 - 0.01 16.0 0.1 0.64 10.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 EGG41883.1 - 0.029 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DSBA PF01323.20 EGG41883.1 - 0.092 12.5 0.1 1.1 9.0 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.14 EGG41883.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DZR PF12773.7 EGG41884.1 - 2.7e-06 27.3 9.5 0.00031 20.7 3.3 2.5 2 1 0 2 2 2 2 Double zinc ribbon PRC PF05239.16 EGG41884.1 - 5.5e-06 26.4 0.5 1e-05 25.5 0.5 1.4 1 0 0 1 1 1 1 PRC-barrel domain zinc_ribbon_2 PF13240.6 EGG41884.1 - 1.6e-05 24.4 7.0 1.6e-05 24.4 7.0 2.3 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EGG41884.1 - 5.8e-05 23.8 3.6 0.058 14.1 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon family GFA PF04828.14 EGG41884.1 - 0.00018 21.8 1.0 6.1 7.3 0.0 3.4 3 0 0 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.24 EGG41884.1 - 0.044 13.9 10.7 2.1 8.6 0.8 3.2 3 0 0 3 3 3 0 B-box zinc finger zinc-ribbons_6 PF07191.12 EGG41884.1 - 0.095 12.7 12.0 0.99 9.4 1.8 3.1 2 1 1 3 3 3 0 zinc-ribbons Prim_Zn_Ribbon PF08273.12 EGG41884.1 - 0.12 12.6 9.4 12 6.3 0.0 3.7 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.10 EGG41884.1 - 0.4 10.5 0.1 0.4 10.5 0.1 4.3 3 1 0 3 3 3 0 A2L zinc ribbon domain HypA PF01155.19 EGG41884.1 - 0.55 10.3 7.4 3 7.9 0.5 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AD PF07776.15 EGG41884.1 - 1.4 9.2 5.9 1.9 8.8 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) DNA_RNApol_7kD PF03604.13 EGG41884.1 - 1.4 8.6 10.2 3.6 7.4 0.1 4.1 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit PHD PF00628.29 EGG41884.1 - 1.7 8.6 8.8 14 5.6 0.1 3.3 3 0 0 3 3 3 0 PHD-finger zf-CHY PF05495.12 EGG41884.1 - 2.3 8.8 10.2 5.2 7.6 2.1 2.6 2 1 0 2 2 2 0 CHY zinc finger Tnp_zf-ribbon_2 PF13842.6 EGG41884.1 - 2.8 8.8 0.0 2.8 8.8 0.0 3.4 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zf_UBZ PF18439.1 EGG41884.1 - 4 7.1 12.9 19 5.0 0.2 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF2197 PF09963.9 EGG41884.1 - 5.5 7.3 7.8 15 5.9 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) Peptidase_S24 PF00717.23 EGG41885.1 - 3e-07 30.3 0.5 3e-07 30.3 0.5 2.2 2 0 0 2 2 2 1 Peptidase S24-like MscL PF01741.18 EGG41885.1 - 0.044 14.1 2.1 0.064 13.6 0.0 2.2 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Vpu PF00558.19 EGG41885.1 - 3.8 7.3 8.7 0.48 10.2 0.4 2.4 2 0 0 2 2 2 0 Vpu protein Peptidase_S49_N PF08496.10 EGG41885.1 - 7.3 6.6 6.5 0.19 11.8 0.3 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HpaB_N PF11794.8 EGG41886.1 - 2.6e-95 319.2 0.0 4.4e-95 318.5 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 EGG41886.1 - 3.2e-71 238.6 0.3 4.4e-71 238.1 0.3 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Acyl-CoA_dh_M PF02770.19 EGG41886.1 - 0.092 13.0 0.0 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Bt_P21 PF05560.11 EGG41886.1 - 0.094 12.3 0.2 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein ATP-grasp_5 PF13549.6 EGG41887.1 - 7.3e-80 267.6 0.8 1.3e-79 266.8 0.8 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EGG41887.1 - 5.2e-52 175.3 2.3 5.3e-52 175.3 0.8 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGG41887.1 - 4.6e-21 75.5 0.7 1.8e-20 73.5 0.1 2.3 2 1 1 3 3 3 1 CoA binding domain CoA_binding PF02629.19 EGG41887.1 - 2.7e-07 31.2 1.0 2.7e-07 31.2 1.0 2.5 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 EGG41887.1 - 1.2e-05 24.9 1.8 2.7e-05 23.9 1.8 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGG41887.1 - 0.002 17.7 0.2 0.0036 16.8 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dak1_2 PF13684.6 EGG41887.1 - 0.0031 16.6 0.3 0.0086 15.2 0.3 1.7 1 1 0 1 1 1 1 Dihydroxyacetone kinase family ATP-grasp PF02222.22 EGG41887.1 - 0.14 11.7 0.2 0.47 10.0 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain RVT_3 PF13456.6 EGG41888.1 - 2.1e-12 46.9 0.0 2.5e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 EGG41888.1 - 1.5e-11 44.7 0.0 1.6e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 RNase H Hex_IIIa PF02455.16 EGG41888.1 - 0.022 13.6 0.1 0.024 13.4 0.1 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Dynactin_p22 PF07426.11 EGG41888.1 - 0.042 13.7 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 DUF475 PF04332.15 EGG41889.1 - 0.0023 17.8 3.9 0.0028 17.5 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF475) E1-N PF14463.6 EGG41889.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain DUF3270 PF11674.8 EGG41889.1 - 1.3 9.2 5.3 2.3 8.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Tmemb_14 PF03647.13 EGG41890.1 - 0.099 13.4 1.2 0.099 13.4 1.2 1.8 1 1 1 2 2 2 0 Transmembrane proteins 14C HTH_5 PF01022.20 EGG41891.1 - 9.2e-10 38.2 0.4 3.6e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EGG41891.1 - 2.6e-05 24.2 0.0 6.9e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 EGG41891.1 - 3.6e-05 23.5 0.1 8.2e-05 22.4 0.0 1.5 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EGG41891.1 - 8.5e-05 22.0 0.4 0.00016 21.1 0.4 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.6 EGG41891.1 - 0.0004 20.3 2.3 0.00057 19.8 2.3 1.4 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_11 PF08279.12 EGG41891.1 - 0.0011 18.9 0.2 0.0019 18.1 0.2 1.4 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 EGG41891.1 - 0.0027 17.6 0.1 0.0054 16.6 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EGG41891.1 - 0.0046 16.8 0.0 0.01 15.7 0.0 1.6 1 1 1 2 2 2 1 MarR family HTH_29 PF13551.6 EGG41891.1 - 0.0058 16.6 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix DUF3781 PF12636.7 EGG41891.1 - 0.012 15.5 1.7 0.015 15.1 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3781) MSV199 PF10553.9 EGG41891.1 - 0.013 15.7 2.0 0.016 15.5 2.0 1.1 1 0 0 1 1 1 0 MSV199 domain DUF4423 PF14394.6 EGG41891.1 - 0.019 14.7 0.8 0.081 12.6 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) Phage_rep_O PF04492.13 EGG41891.1 - 0.03 14.9 0.2 0.042 14.4 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_12 PF08461.10 EGG41891.1 - 0.033 14.1 0.2 0.06 13.3 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain LexA_DNA_bind PF01726.16 EGG41891.1 - 0.035 13.9 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain DprA_WH PF17782.1 EGG41891.1 - 0.041 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 DprA winged helix domain Nop52 PF05997.12 EGG41891.1 - 0.047 13.5 0.3 0.057 13.2 0.3 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 B-block_TFIIIC PF04182.12 EGG41891.1 - 0.05 13.8 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_1 PF00126.27 EGG41891.1 - 0.052 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Rrf2 PF02082.20 EGG41891.1 - 0.064 13.6 0.4 0.15 12.4 0.2 1.7 1 1 1 2 2 2 0 Transcriptional regulator HTH_9 PF08221.11 EGG41891.1 - 0.14 12.3 0.2 0.36 11.0 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain MobC PF05713.11 EGG41891.1 - 0.14 12.6 2.0 0.48 10.9 0.2 2.2 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Radical_SAM PF04055.21 EGG41892.1 - 1e-14 55.3 0.1 2.2e-14 54.2 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily NicO PF03824.16 EGG41893.1 - 1.1e-05 24.9 17.3 1.6e-05 24.4 17.3 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Thioredoxin_3 PF13192.6 EGG41895.1 - 5.2e-10 39.2 0.1 6.8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 EGG41895.1 - 0.0016 18.6 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin KaiB PF07689.12 EGG41895.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 KaiB domain DsbD PF02683.15 EGG41896.1 - 6.6e-16 58.8 16.9 6.6e-16 58.8 16.9 1.5 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 EGG41896.1 - 4.1e-05 23.6 8.9 4.1e-05 23.6 8.9 2.7 2 1 1 3 3 3 2 Cytochrome C biogenesis protein transmembrane region HTH_AsnC-type PF13404.6 EGG41897.1 - 5.6e-13 48.5 0.1 9.4e-13 47.8 0.1 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EGG41897.1 - 7.3e-11 41.5 0.1 1.3e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Arc_trans_TRASH PF08394.10 EGG41897.1 - 2.7e-05 24.4 4.4 4.8e-05 23.6 4.4 1.4 1 0 0 1 1 1 1 Archaeal TRASH domain TrmB PF01978.19 EGG41897.1 - 8.7e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.6 EGG41897.1 - 0.00041 19.7 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 EGG41897.1 - 0.00076 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_9 PF08221.11 EGG41897.1 - 0.0057 16.7 0.0 0.0096 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2250 PF10007.9 EGG41897.1 - 0.0057 16.7 1.5 0.22 11.6 1.5 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_38 PF13936.6 EGG41897.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EGG41897.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 EGG41897.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF4423 PF14394.6 EGG41897.1 - 0.043 13.5 0.1 0.095 12.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) zf-FCS PF06467.14 EGG41897.1 - 0.045 13.7 3.2 0.098 12.6 3.2 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ATPase-cat_bd PF12156.8 EGG41897.1 - 0.065 14.0 0.6 0.065 14.0 0.6 1.8 3 0 0 3 3 2 0 Putative metal-binding domain of cation transport ATPase Sigma70_r4_2 PF08281.12 EGG41897.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 He_PIG PF05345.12 EGG41898.1 - 5.5e-05 23.3 0.6 5.5e-05 23.3 0.6 2.5 3 0 0 3 3 3 1 Putative Ig domain CCDC53 PF10152.9 EGG41898.1 - 0.022 15.1 2.2 0.1 13.0 0.5 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SPATA3 PF15662.5 EGG41898.1 - 6.1 7.4 6.8 0.84 10.2 2.9 1.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family Trypan_PARP PF05887.11 EGG41899.1 - 5.2e-05 23.2 4.7 6.7e-05 22.9 2.7 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) EB PF01683.18 EGG41899.1 - 0.0043 17.3 5.3 5.1 7.5 0.3 4.6 3 1 0 3 3 3 1 EB module MG2 PF01835.19 EGG41899.1 - 0.0049 17.3 0.0 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 MG2 domain Big_3_5 PF16640.5 EGG41899.1 - 0.024 14.8 3.0 0.06 13.5 3.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) SPESP1 PF15754.5 EGG41899.1 - 0.039 13.1 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF2345 PF10106.9 EGG41899.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) CarboxypepD_reg PF13620.6 EGG41899.1 - 0.072 13.4 0.4 0.17 12.2 0.4 1.6 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain HTH_55 PF18622.1 EGG41899.1 - 0.099 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RctB helix turn helix domain Adeno_E1A PF02703.14 EGG41899.1 - 9.1 5.8 9.1 8.8 5.8 7.5 1.6 1 1 1 2 2 2 0 Early E1A protein MG2 PF01835.19 EGG41900.1 - 0.00062 20.2 0.0 0.00088 19.7 0.0 1.2 1 0 0 1 1 1 1 MG2 domain Herpes_UL16 PF03044.14 EGG41900.1 - 0.0086 15.4 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL16/UL94 family PSA_CBD PF18341.1 EGG41900.1 - 0.036 14.1 0.3 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain HTH_10 PF04967.12 EGG41901.1 - 0.13 12.1 0.1 24 4.8 0.1 2.5 2 0 0 2 2 2 0 HTH DNA binding domain Tachystatin_B PF11478.8 EGG41901.1 - 0.14 12.1 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B ZT_dimer PF16916.5 EGG41902.1 - 9.1e-48 160.3 20.5 2.6e-18 65.9 3.3 3.2 3 0 0 3 3 3 3 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 EGG41902.1 - 8e-41 140.0 18.0 1e-40 139.6 18.0 1.1 1 0 0 1 1 1 1 Cation efflux family Fe_dep_repr_C PF02742.15 EGG41902.1 - 0.15 12.2 4.8 6.3 7.0 0.3 3.7 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain BON PF04972.17 EGG41902.1 - 2.4 8.5 6.3 0.7 10.2 0.1 3.2 4 1 0 4 4 4 0 BON domain AMP-binding_C_2 PF14535.6 EGG41902.1 - 3.3 8.1 10.0 2.3 8.6 1.9 3.1 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain PHO4 PF01384.20 EGG41902.1 - 8.1 5.4 9.1 64 2.4 8.2 2.3 1 1 0 1 1 1 0 Phosphate transporter family Zip PF02535.22 EGG41903.1 - 0.0003 20.1 20.2 0.0003 20.1 20.2 2.8 1 1 1 2 2 2 1 ZIP Zinc transporter DUF2070 PF09843.9 EGG41903.1 - 0.63 8.3 20.0 0.67 8.2 6.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Cu-oxidase_3 PF07732.15 EGG41904.1 - 2e-22 79.4 6.6 1.4e-19 70.2 0.9 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG41904.1 - 1.7e-21 76.4 10.2 5.2e-11 42.4 0.4 3.2 2 1 0 2 2 2 2 Multicopper oxidase SQAPI PF16845.5 EGG41905.1 - 0.042 14.2 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Aspartic acid proteinase inhibitor EMP24_GP25L PF01105.24 EGG41905.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Ribosomal_S13 PF00416.22 EGG41907.1 - 2.8e-37 128.0 0.0 3.3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF4238 PF14022.6 EGG41907.1 - 0.095 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) S4 PF01479.25 EGG41908.1 - 2e-10 40.2 0.1 8.2e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 S4 domain SIS PF01380.22 EGG41909.1 - 7.8e-51 171.3 3.3 7.2e-26 90.6 2.4 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGG41909.1 - 1.4e-21 77.1 0.0 6.4e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGG41909.1 - 3.2e-16 59.4 0.5 1.2e-15 57.5 0.0 2.2 3 0 0 3 3 3 1 Glutamine amidotransferase domain SIS_2 PF13580.6 EGG41909.1 - 1.3e-06 28.5 2.9 0.00063 19.8 0.3 3.7 2 1 1 3 3 3 2 SIS domain GATase_4 PF13230.6 EGG41909.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DBI_PRT PF02277.17 EGG41910.1 - 3.4e-13 49.5 0.1 4.9e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyltransferase Lactamase_B PF00753.27 EGG41911.1 - 1.7e-21 77.1 2.4 9.9e-20 71.4 2.4 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG41911.1 - 1.4e-05 24.8 0.1 2.2e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain COR PF16095.5 EGG41911.1 - 0.0066 16.3 0.3 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain DUF1776 PF08643.10 EGG41911.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) YjeF_N PF03853.15 EGG41912.1 - 1.2e-46 158.7 0.0 1.4e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus Translin PF01997.16 EGG41913.1 - 7.3e-11 42.4 0.3 5.6e-09 36.3 0.1 2.3 1 1 1 2 2 2 2 Translin family RNA_pol_N PF01194.17 EGG41914.1 - 1e-28 99.4 0.3 1.4e-28 98.9 0.3 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit tRNA-synt_2 PF00152.20 EGG41914.1 - 0.065 12.3 0.0 0.074 12.1 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Enolase_C PF00113.22 EGG41915.1 - 1.3e-57 195.3 0.1 1.8e-57 194.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGG41915.1 - 3.2e-21 75.9 0.0 8.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGG41915.1 - 8.3e-05 22.3 0.0 0.00025 20.7 0.0 1.7 1 1 1 2 2 2 1 Enolase C-terminal domain-like DUF155 PF02582.14 EGG41915.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Ribosomal_S2 PF00318.20 EGG41916.1 - 3.8e-20 72.0 0.4 8.2e-11 41.5 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein S2 Memo PF01875.17 EGG41917.1 - 2.3e-82 276.2 0.0 2.6e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.18 EGG41917.1 - 0.017 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase GHMP_kinases_N PF00288.26 EGG41918.1 - 3.4e-17 62.4 0.2 7.1e-17 61.4 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG41918.1 - 1.5e-12 47.7 0.1 3.2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EGG41918.1 - 0.0056 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF573 PF04504.14 EGG41918.1 - 0.022 15.4 0.2 0.052 14.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF573 AA_kinase PF00696.28 EGG41919.1 - 1.7e-30 106.4 0.0 1.9e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family RsgA_GTPase PF03193.16 EGG41919.1 - 0.049 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF1967 PF09269.11 EGG41919.1 - 0.069 13.1 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) NUDIX PF00293.28 EGG41920.1 - 8.8e-18 64.6 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain polyprenyl_synt PF00348.17 EGG41921.1 - 3.6e-70 235.9 0.1 4.4e-70 235.7 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EGG41921.1 - 0.0024 17.2 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain tRNA-synt_1c PF00749.21 EGG41922.1 - 2.2e-77 260.1 0.0 3.5e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGG41922.1 - 4.3e-22 78.8 0.1 8.7e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain FAA_hydrolase PF01557.18 EGG41923.1 - 1.3e-69 234.2 0.0 1.7e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 EGG41923.1 - 0.0021 18.9 0.0 0.0056 17.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) Acetyltransf_1 PF00583.25 EGG41924.1 - 2.3e-07 31.0 0.0 5.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG41924.1 - 9.1e-05 22.8 0.1 0.00026 21.4 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG41924.1 - 9.2e-05 22.4 0.0 0.00043 20.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGG41924.1 - 0.00016 21.3 0.6 0.01 15.4 0.1 2.2 2 0 0 2 2 2 1 GNAT acetyltransferase FR47 PF08445.10 EGG41924.1 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGG41924.1 - 0.006 17.3 0.1 0.01 16.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG41924.1 - 0.034 14.2 0.0 0.34 11.0 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain PABP PF00658.18 EGG41924.1 - 0.037 14.2 0.2 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Rieske PF00355.26 EGG41925.1 - 2.9e-18 65.6 0.1 3.6e-18 65.3 0.1 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EGG41925.1 - 6.8e-08 32.4 0.0 8.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0147 PF03685.13 EGG41926.1 - 4.9e-31 106.6 2.1 5.6e-31 106.4 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) UPF0253 PF06786.12 EGG41926.1 - 0.0028 17.9 0.0 0.64 10.3 0.0 2.3 1 1 0 2 2 2 2 Uncharacterised protein family (UPF0253) PPDK_N PF01326.19 EGG41926.1 - 0.055 12.7 0.2 0.067 12.5 0.2 1.3 1 1 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Glyco_hydro_20b PF02838.15 EGG41926.1 - 0.081 13.7 0.4 0.096 13.5 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 CUTL PF16557.5 EGG41926.1 - 0.14 12.3 0.3 0.84 9.9 0.1 2.1 1 1 1 2 2 2 0 CUT1-like DNA-binding domain of SATB Methyltransf_25 PF13649.6 EGG41927.1 - 0.079 13.7 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PA-IIL PF07472.11 EGG41927.1 - 0.13 12.6 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) CorA PF01544.18 EGG41929.1 - 4.5e-63 213.3 6.2 7.2e-63 212.6 6.2 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TATR PF03430.13 EGG41929.1 - 0.011 14.1 0.1 0.023 13.1 0.0 1.5 2 0 0 2 2 2 0 Trans-activating transcriptional regulator DUF2207 PF09972.9 EGG41929.1 - 0.03 13.1 0.6 0.04 12.7 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2397 PF09660.10 EGG41929.1 - 0.092 11.6 0.4 0.13 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) APG17 PF04108.12 EGG41929.1 - 0.11 11.7 4.0 0.13 11.3 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF1993 PF09351.10 EGG41929.1 - 0.14 12.3 0.3 1.5 9.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) T3SchapCesA PF11439.8 EGG41929.1 - 0.24 11.5 1.3 1.8 8.8 1.3 2.2 1 1 0 1 1 1 0 Type III secretion system filament chaperone CesA FtsX PF02687.21 EGG41929.1 - 3.2 8.3 6.2 6.3 7.3 6.2 1.4 1 0 0 1 1 1 0 FtsX-like permease family EMP24_GP25L PF01105.24 EGG41929.1 - 4.3 7.2 8.0 0.12 12.4 0.6 2.2 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Usp PF00582.26 EGG41931.1 - 3.1e-22 79.6 0.0 3.5e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family TAL_FSA PF00923.19 EGG41932.1 - 6.2e-61 206.3 0.0 4.2e-60 203.5 0.0 2.0 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Transketolase_C PF02780.20 EGG41933.1 - 1.4e-30 105.7 0.0 2.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGG41933.1 - 1.1e-29 103.4 0.0 1.5e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 EGG41933.1 - 0.0051 17.1 0.0 0.0096 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_N PF00456.21 EGG41934.1 - 1.2e-49 169.1 0.3 2.3e-48 164.9 0.3 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Ribul_P_3_epim PF00834.19 EGG41934.1 - 3.2e-49 167.0 0.0 4.6e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DXP_synthase_N PF13292.6 EGG41934.1 - 1e-05 24.9 0.1 8.4e-05 21.9 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EGG41934.1 - 1.6e-05 24.0 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGG41934.1 - 3.4e-05 23.7 0.0 7.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 EGG41934.1 - 6e-05 22.0 0.2 0.00068 18.5 0.0 2.2 2 0 0 2 2 2 1 XFP N-terminal domain DUF393 PF04134.12 EGG41935.1 - 0.0045 18.3 0.0 0.0063 17.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF393 Peptidase_M17 PF00883.21 EGG41936.1 - 6.8e-119 396.8 0.0 8.6e-119 396.4 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EGG41936.1 - 3.8e-17 62.3 0.2 1.4e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain ABC_tran PF00005.27 EGG41939.1 - 7.3e-40 136.7 0.6 8.5e-19 68.4 0.2 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EGG41939.1 - 1.1e-10 41.2 2.8 1.1e-10 41.2 2.8 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 EGG41939.1 - 1.5e-08 34.1 11.1 3.7e-08 32.8 5.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.19 EGG41939.1 - 1.8e-07 30.8 9.9 0.0022 17.4 1.5 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4_6 PF12837.7 EGG41939.1 - 2.1e-07 30.7 13.2 2.8e-06 27.1 4.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain RsgA_GTPase PF03193.16 EGG41939.1 - 4e-06 26.8 0.3 0.031 14.2 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase Fer4_2 PF12797.7 EGG41939.1 - 5.5e-06 26.2 2.2 5.5e-06 26.2 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 EGG41939.1 - 4.7e-05 23.4 12.5 8.2e-05 22.7 12.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG41939.1 - 0.0001 22.4 12.6 0.00017 21.7 1.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_21 PF13304.6 EGG41939.1 - 0.00015 21.7 9.1 0.57 9.9 0.0 4.7 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system Fer4_7 PF12838.7 EGG41939.1 - 0.00044 20.8 10.7 0.0012 19.4 10.9 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain NB-ARC PF00931.22 EGG41939.1 - 0.00074 18.8 0.2 0.84 8.8 0.1 2.9 2 1 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 EGG41939.1 - 0.00083 19.8 0.0 0.47 10.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGG41939.1 - 0.0026 17.8 2.3 0.55 10.3 1.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGG41939.1 - 0.0044 16.7 0.3 0.47 10.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 EGG41939.1 - 0.011 15.8 0.9 2 8.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain Fer4_16 PF13484.6 EGG41939.1 - 0.011 16.6 11.1 0.014 16.3 1.9 2.6 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Rad17 PF03215.15 EGG41939.1 - 0.022 14.7 0.2 0.29 11.0 0.0 2.5 3 0 0 3 3 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 EGG41939.1 - 0.023 14.9 0.3 9 6.6 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_9 PF13187.6 EGG41939.1 - 0.026 14.7 10.6 0.083 13.1 10.8 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain RuvB_N PF05496.12 EGG41939.1 - 0.071 12.9 0.1 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGG41939.1 - 0.072 13.5 0.2 2.6 8.5 0.1 2.9 2 1 0 2 2 2 0 RNA helicase AAA PF00004.29 EGG41939.1 - 0.088 13.2 0.4 7.7 7.0 0.0 3.1 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) His_Phos_1 PF00300.22 EGG41939.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Fer4_3 PF12798.7 EGG41939.1 - 0.21 12.6 16.0 0.11 13.5 5.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 EGG41939.1 - 0.21 12.2 14.0 0.055 14.0 3.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_15 PF13175.6 EGG41939.1 - 0.25 11.0 9.2 2.1 8.0 0.9 3.2 2 2 1 3 3 3 0 AAA ATPase domain Fer4_17 PF13534.6 EGG41939.1 - 1.6 9.4 9.0 0.19 12.3 1.2 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG41939.1 - 2.4 8.6 8.3 9 6.8 8.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_23 PF13476.6 EGG41939.1 - 2.5 8.6 11.1 17 5.8 2.3 3.6 2 2 0 2 2 2 0 AAA domain Met_10 PF02475.16 EGG41940.1 - 7.8e-60 202.0 0.1 9.6e-60 201.7 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 EGG41940.1 - 2.6e-06 27.1 0.1 3.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EGG41940.1 - 2.4e-05 24.0 0.1 4.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EGG41940.1 - 7.6e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGG41940.1 - 0.00022 21.1 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 EGG41940.1 - 0.00022 20.5 0.0 0.00027 20.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 EGG41940.1 - 0.00054 20.6 0.0 0.00093 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGG41940.1 - 0.00076 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 EGG41940.1 - 0.0065 16.1 0.1 0.93 9.1 0.1 2.2 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F DNA_methylase PF00145.17 EGG41940.1 - 0.02 14.2 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase ADH_zinc_N PF00107.26 EGG41940.1 - 0.03 14.3 0.0 0.13 12.3 0.0 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.7 EGG41940.1 - 0.037 13.9 0.2 0.11 12.5 0.2 1.6 1 1 1 2 2 2 0 Methyltransferase domain MethyltransfD12 PF02086.15 EGG41940.1 - 0.05 13.3 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_16 PF10294.9 EGG41940.1 - 0.055 13.2 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Phage_holin_3_6 PF07332.11 EGG41941.1 - 0.39 10.8 5.2 0.46 10.5 5.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 EGG41941.1 - 1.3 7.7 4.0 1.5 7.5 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Acetyltransf_1 PF00583.25 EGG41942.1 - 6.1e-20 71.6 0.2 7.7e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG41942.1 - 1.7e-14 54.0 0.6 1.7e-14 54.0 0.6 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG41942.1 - 1.3e-12 47.8 0.3 1.9e-12 47.2 0.3 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG41942.1 - 1.2e-09 38.0 0.2 4.9e-09 36.0 0.1 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 EGG41942.1 - 0.00074 19.2 0.0 0.0025 17.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGG41942.1 - 0.001 19.7 0.0 0.0014 19.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGG41942.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 EGG41942.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGG41942.1 - 0.011 15.9 0.3 0.014 15.5 0.3 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4821 PF16092.5 EGG41942.1 - 0.015 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Acetyltransf_CG PF14542.6 EGG41942.1 - 0.024 14.7 0.1 0.048 13.8 0.1 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M50 PF02163.22 EGG41943.1 - 1.5e-12 47.3 14.1 1.2e-08 34.6 0.5 2.8 1 1 0 2 2 2 2 Peptidase family M50 DUF3698 PF12479.8 EGG41943.1 - 0.0092 16.5 0.4 0.026 15.0 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3698) Pribosyltran PF00156.27 EGG41945.1 - 3.5e-15 55.9 0.2 4.7e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EGG41945.1 - 0.00036 20.1 0.1 0.00059 19.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 EGG41945.1 - 0.00055 19.4 0.3 0.00078 18.9 0.3 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SmpB PF01668.18 EGG41945.1 - 0.0087 15.9 0.4 0.014 15.3 0.2 1.5 2 0 0 2 2 2 1 SmpB protein TENA_THI-4 PF03070.16 EGG41946.1 - 1.6e-12 47.7 0.4 1.8e-12 47.5 0.4 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 EGG41946.1 - 2.8e-11 43.5 0.0 3.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme DUF2812 PF11193.8 EGG41946.1 - 0.0077 16.4 0.1 0.028 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2812) polyprenyl_synt PF00348.17 EGG41947.1 - 1.5e-47 161.8 0.1 2e-47 161.4 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Proton_antipo_M PF00361.20 EGG41948.1 - 3.7e-66 223.3 25.2 3.7e-66 223.3 25.2 2.4 1 1 1 2 2 2 1 Proton-conducting membrane transporter DUF5592 PF17332.2 EGG41948.1 - 0.13 12.9 0.1 0.13 12.9 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5592) DUF2759 PF10958.8 EGG41948.1 - 0.19 11.5 0.0 0.19 11.5 0.0 4.9 3 2 0 3 3 3 0 Protein of unknown function (DUF2759) Proton_antipo_M PF00361.20 EGG41949.1 - 2.5e-58 197.6 30.6 4e-54 183.8 30.2 3.0 3 0 0 3 3 3 2 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 EGG41949.1 - 2.6e-13 49.8 2.0 2.6e-13 49.8 2.0 2.8 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 EGG41949.1 - 0.00056 19.6 0.2 0.001 18.8 0.2 1.4 1 0 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Proton_antipo_M PF00361.20 EGG41950.1 - 2.9e-61 207.3 24.6 2.9e-61 207.3 24.6 1.9 1 1 1 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 EGG41950.1 - 1.4e-05 25.0 0.4 0.00029 20.8 0.0 3.0 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.24 EGG41951.1 - 7.6e-23 80.1 5.6 9.5e-23 79.8 5.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L VPDSG-CTERM PF18205.1 EGG41951.1 - 9.1 6.2 9.5 14 5.6 1.4 3.1 3 1 0 3 3 3 0 VPDSG-CTERM motif Oxidored_q3 PF00499.20 EGG41952.1 - 2.7e-22 79.0 14.2 4.1e-22 78.4 14.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MIG-14_Wnt-bd PF06664.12 EGG41952.1 - 0.067 12.4 4.8 0.083 12.1 4.1 1.5 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Fer4 PF00037.27 EGG41953.1 - 7.6e-12 44.5 10.8 3.2e-09 36.2 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EGG41953.1 - 4.4e-09 36.3 16.8 3e-05 24.0 11.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGG41953.1 - 1e-08 35.6 9.4 1.6e-08 35.0 9.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EGG41953.1 - 2e-08 34.2 20.1 4.2e-06 26.8 10.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG41953.1 - 1.3e-07 31.6 6.2 2.3e-07 30.9 6.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG41953.1 - 9e-06 25.5 9.8 0.0014 18.6 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EGG41953.1 - 1.9e-05 24.5 11.8 4.3e-05 23.4 1.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 EGG41953.1 - 0.0001 22.6 8.1 0.012 16.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EGG41953.1 - 0.00022 21.6 9.5 0.012 16.0 1.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGG41953.1 - 0.00097 20.0 9.7 0.0047 17.8 0.2 2.4 1 1 2 3 3 3 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 EGG41953.1 - 0.0012 19.4 10.2 0.028 14.9 0.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_15 PF13459.6 EGG41953.1 - 0.0021 18.7 5.0 0.26 12.1 0.4 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.6 EGG41953.1 - 0.0041 17.6 4.2 0.21 12.2 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EGG41953.1 - 0.011 16.6 4.1 0.011 16.6 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EGG41953.1 - 0.21 11.8 9.4 0.18 12.0 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EGG41953.1 - 1.7 9.5 10.9 0.58 11.0 0.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain NADHdh PF00146.21 EGG41954.1 - 3.8e-96 321.9 23.1 5.7e-96 321.3 23.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase Complex1_49kDa PF00346.19 EGG41955.1 - 6.2e-75 251.8 0.0 9.6e-58 195.4 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ribosomal_S5_C PF03719.15 EGG41955.1 - 0.097 12.1 0.1 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Complex1_30kDa PF00329.19 EGG41956.1 - 1.1e-34 119.7 0.0 1.4e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Alkyl_sulf_dimr PF14863.6 EGG41956.1 - 0.091 13.2 0.0 1.1 9.8 0.0 2.0 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Oxidored_q6 PF01058.22 EGG41957.1 - 7.7e-25 87.2 0.1 1.1e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.19 EGG41958.1 - 1.4e-18 66.9 0.6 1.9e-18 66.5 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 MPS-4 PF17523.2 EGG41958.1 - 0.058 13.5 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 AhpC-TSA PF00578.21 EGG41959.1 - 3.9e-33 114.0 0.0 4.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG41959.1 - 6.2e-21 74.6 0.0 7.1e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGG41959.1 - 0.074 13.2 0.0 0.24 11.5 0.0 1.7 1 1 0 2 2 2 0 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 EGG41959.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC Biotin_lipoyl PF00364.22 EGG41960.1 - 9.5e-17 60.6 4.6 1.7e-16 59.8 4.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGG41960.1 - 2.7e-10 39.9 2.7 1.6e-09 37.4 0.3 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGG41960.1 - 9.7e-05 23.0 0.5 0.033 14.9 0.1 2.5 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EGG41960.1 - 0.0011 18.3 1.8 0.061 12.5 0.1 2.7 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 EGG41960.1 - 0.004 17.1 1.5 0.0078 16.2 1.5 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EGG41960.1 - 0.014 15.3 0.6 0.032 14.1 0.6 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein Big_3_3 PF13750.6 EGG41960.1 - 0.017 14.8 2.0 0.036 13.7 0.7 2.0 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) QRPTase_N PF02749.16 EGG41960.1 - 0.022 14.8 0.1 0.074 13.1 0.0 1.9 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2118 PF09891.9 EGG41960.1 - 0.033 14.1 0.6 0.057 13.4 0.1 1.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DUF4164 PF13747.6 EGG41960.1 - 0.055 13.8 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Peptidase_M23 PF01551.22 EGG41960.1 - 0.076 13.2 2.0 0.76 10.0 0.2 2.6 2 1 1 3 3 3 0 Peptidase family M23 eIF-1a PF01176.19 EGG41960.1 - 0.077 12.8 0.3 1.4 8.8 0.0 2.7 2 1 0 2 2 2 0 Translation initiation factor 1A / IF-1 CPSase_L_D2 PF02786.17 EGG41961.1 - 5.3e-69 231.9 0.0 7.9e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGG41961.1 - 7e-44 148.9 0.0 1.3e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGG41961.1 - 1.8e-33 114.8 0.0 4e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 EGG41961.1 - 2.9e-10 40.0 0.1 5.7e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGG41961.1 - 6.2e-08 32.4 0.2 1.5e-07 31.2 0.2 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 EGG41961.1 - 1.2e-06 28.3 0.0 6.4e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EGG41961.1 - 1.9e-06 28.0 0.0 4.5e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EGG41961.1 - 1.2e-05 24.9 0.1 4.6e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain KRTDAP PF15200.6 EGG41961.1 - 0.027 14.3 0.0 0.083 12.7 0.0 1.8 2 0 0 2 2 2 0 Keratinocyte differentiation-associated ATPgrasp_Ter PF15632.6 EGG41961.1 - 0.059 13.1 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EGG41961.1 - 0.11 12.3 0.4 0.4 10.4 0.0 2.1 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LpxI_N PF17930.1 EGG41961.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain Carboxyl_trans PF01039.22 EGG41962.1 - 3.3e-184 613.1 0.0 3.8e-184 613.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGG41962.1 - 8.5e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) Myticin-prepro PF10690.9 EGG41963.1 - 0.1 12.8 6.2 0.15 12.3 6.2 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel AAA PF00004.29 EGG41964.1 - 1.3e-12 48.3 0.0 3.6e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGG41964.1 - 4.2e-08 33.1 0.0 1.4e-07 31.4 0.0 1.9 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EGG41964.1 - 8.9e-06 25.8 0.4 3.8e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 EGG41964.1 - 0.00079 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EGG41964.1 - 0.0024 17.9 0.0 0.0069 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGG41964.1 - 0.006 16.6 0.1 0.04 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG41964.1 - 0.0068 16.7 0.3 0.18 12.1 0.1 2.8 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 EGG41964.1 - 0.0073 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 EGG41964.1 - 0.0097 16.3 0.0 0.02 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGG41964.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGG41964.1 - 0.028 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RFC1 PF08519.12 EGG41964.1 - 0.028 14.6 0.4 0.062 13.5 0.0 1.8 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Mg_chelatase PF01078.21 EGG41964.1 - 0.03 13.7 0.2 0.12 11.7 0.0 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 EGG41964.1 - 0.054 12.9 0.1 3.3 7.1 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein AAA_24 PF13479.6 EGG41964.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EGG41964.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EGG41964.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG41964.1 - 0.071 13.7 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGG41964.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 EGG41964.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Inositol_P PF00459.25 EGG41966.1 - 1.3e-27 97.0 0.0 1.5e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 EGG41966.1 - 0.00035 20.1 0.1 0.00058 19.4 0.1 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NAD_binding_1 PF00175.21 EGG41967.1 - 6.9e-11 42.8 0.0 1.4e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGG41967.1 - 2.8e-08 34.0 0.0 4.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Methyltransf_34 PF11312.8 EGG41967.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase NAD_binding_6 PF08030.12 EGG41967.1 - 0.035 14.2 0.2 0.14 12.2 0.1 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGG41967.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF1059 PF06348.11 EGG41968.1 - 4.4e-06 26.8 0.1 4.7e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) GlutR_N PF05201.15 EGG41969.1 - 2.3e-25 89.1 0.0 3.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EGG41969.1 - 1.2e-18 67.5 0.0 5.1e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGG41969.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EGG41969.1 - 0.046 14.3 0.0 0.096 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 EGG41969.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MEF2_binding PF09047.10 EGG41970.1 - 0.049 13.5 10.5 0.42 10.5 1.0 2.8 2 0 0 2 2 2 0 MEF2 binding Herpes_UL17 PF04559.12 EGG41970.1 - 0.33 9.7 4.2 0.38 9.5 4.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein Lyase_1 PF00206.20 EGG41971.1 - 1.8e-50 172.1 0.1 3.3e-49 168.0 0.0 2.2 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 EGG41971.1 - 1e-13 51.8 0.0 8e-13 48.9 0.0 2.4 3 0 0 3 3 3 1 Argininosuccinate lyase C-terminal FeS_assembly_P PF01883.19 EGG41972.1 - 1.6e-15 57.0 0.1 2.2e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein HMA PF00403.26 EGG41972.1 - 0.11 12.9 2.3 0.41 11.1 0.1 2.3 2 1 0 2 2 2 0 Heavy-metal-associated domain Fer2_3 PF13085.6 EGG41973.1 - 5.2e-31 106.9 0.0 1.1e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 EGG41973.1 - 8.9e-12 45.3 4.6 9.5e-12 45.2 2.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG41973.1 - 1.6e-10 41.0 2.4 1.6e-10 41.0 2.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGG41973.1 - 3.8e-09 37.0 13.1 2.4e-07 31.2 4.1 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EGG41973.1 - 5.5e-09 36.4 12.7 2.6e-07 31.1 3.4 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG41973.1 - 2.8e-08 33.8 11.9 2.6e-07 30.7 2.8 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGG41973.1 - 8.5e-07 29.8 2.2 8.5e-07 29.8 2.2 2.1 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 EGG41973.1 - 2.8e-05 24.3 5.7 0.029 14.6 0.2 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 EGG41973.1 - 3.8e-05 23.3 1.1 3.8e-05 23.3 1.1 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer2 PF00111.27 EGG41973.1 - 0.00022 21.1 0.1 0.00022 21.1 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_6 PF12837.7 EGG41973.1 - 0.0021 18.1 1.8 0.0021 18.1 1.8 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_2 PF12797.7 EGG41973.1 - 0.024 14.7 2.0 0.024 14.7 2.0 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.7 EGG41973.1 - 0.087 13.4 1.3 0.087 13.4 1.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 EGG41973.1 - 0.19 11.9 13.5 0.13 12.4 8.0 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGG41973.1 - 0.88 10.7 21.4 0.38 11.8 4.6 3.2 3 1 0 3 3 3 0 4Fe-4S binding domain Sdh_cyt PF01127.22 EGG41974.1 - 1.8e-07 31.2 3.0 2.1e-07 31.0 3.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4179 PF13786.6 EGG41974.1 - 0.29 11.7 2.2 0.88 10.1 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Sdh_cyt PF01127.22 EGG41975.1 - 9.3e-08 32.1 4.5 1.3e-07 31.7 3.8 1.6 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 EGG41975.1 - 0.01 15.9 2.4 0.081 13.0 0.0 2.2 2 0 0 2 2 2 0 Fumarate reductase subunit D Fumarate_red_C PF02300.17 EGG41975.1 - 0.25 11.4 3.7 0.1 12.7 0.8 1.7 2 0 0 2 2 2 0 Fumarate reductase subunit C FAD_binding_2 PF00890.24 EGG41976.1 - 2.3e-98 330.0 0.1 2.9e-98 329.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGG41976.1 - 2.9e-37 127.5 0.6 4.8e-37 126.8 0.6 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EGG41976.1 - 3e-07 30.0 0.0 0.00048 19.5 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGG41976.1 - 0.00082 18.6 0.0 0.045 12.8 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGG41976.1 - 0.0012 18.2 0.0 0.061 12.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGG41976.1 - 0.0019 17.5 0.2 0.0072 15.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EGG41976.1 - 0.031 13.3 0.1 0.062 12.3 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EGG41976.1 - 0.034 13.7 0.3 0.42 10.1 0.1 2.3 2 2 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG41976.1 - 0.065 11.9 0.7 2.7 6.6 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein PadR PF03551.14 EGG41977.1 - 1.6e-10 40.8 0.1 2.9e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 EGG41977.1 - 1.7e-05 24.7 0.6 0.00021 21.2 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix RTP PF02334.16 EGG41977.1 - 0.0017 19.0 0.3 0.047 14.3 0.0 2.3 1 1 1 2 2 2 1 Replication terminator protein Mrr_N PF14338.6 EGG41977.1 - 0.029 14.5 0.4 0.12 12.5 0.1 2.2 3 0 0 3 3 3 0 Mrr N-terminal domain PEP_mutase PF13714.6 EGG41978.1 - 8.9e-50 169.4 0.1 1e-49 169.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGG41978.1 - 4.1e-15 55.3 0.1 2.1e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Isocitrate lyase family Alba PF01918.21 EGG41979.1 - 1.6e-12 47.1 0.1 2.5e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 EGG41979.1 - 0.0097 15.9 0.4 0.66 9.9 0.0 2.2 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Ysc84 PF04366.12 EGG41979.1 - 0.018 14.8 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Las17-binding protein actin regulator Waikav_capsid_1 PF12264.8 EGG41979.1 - 0.059 12.9 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Waikavirus capsid protein 1 HEAT_2 PF13646.6 EGG41980.1 - 2e-17 63.3 0.4 1.5e-07 31.7 0.1 2.5 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.22 EGG41980.1 - 3.3e-10 39.3 0.1 0.016 15.4 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EGG41980.1 - 3.5e-06 27.1 3.0 0.36 10.9 0.0 3.1 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EGG41980.1 - 2.7e-05 24.4 2.8 1.1 9.6 0.0 4.0 4 1 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 EGG41980.1 - 0.00012 22.5 0.0 0.41 11.2 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat ERAP1_C PF11838.8 EGG41980.1 - 0.00026 20.7 0.2 0.12 11.9 0.0 2.2 1 1 1 2 2 2 2 ERAP1-like C-terminal domain DNA_pol3_delta PF06144.13 EGG41980.1 - 0.00039 20.3 0.8 0.071 12.9 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit DUF4042 PF13251.6 EGG41980.1 - 0.019 14.7 0.1 7.2 6.3 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) CLASP_N PF12348.8 EGG41980.1 - 0.033 13.8 0.2 0.11 12.1 0.1 2.0 1 1 1 2 2 2 0 CLASP N terminal HEAT_PBS PF03130.16 EGG41980.1 - 0.041 14.6 0.0 26 5.9 0.1 3.8 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 EGG41980.1 - 0.081 13.1 0.4 15 5.8 0.0 2.9 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 NAD_binding_1 PF00175.21 EGG41981.1 - 6.2e-14 52.6 0.0 1e-13 51.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGG41981.1 - 8.4e-08 32.5 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGG41981.1 - 0.045 13.9 0.1 0.16 12.1 0.1 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Methyltransf_34 PF11312.8 EGG41981.1 - 0.048 12.9 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase CTP_transf_like PF01467.26 EGG41982.1 - 0.024 14.8 0.0 0.041 14.1 0.0 1.7 1 1 0 1 1 1 0 Cytidylyltransferase-like Aminotran_4 PF01063.19 EGG41983.1 - 1.8e-44 152.2 0.0 2.2e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF22 PF01629.16 EGG41983.1 - 0.025 14.3 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 GFO_IDH_MocA PF01408.22 EGG41984.1 - 7.5e-25 88.1 0.0 1.3e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGG41984.1 - 1.5e-06 28.2 0.1 2.9e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF3228 PF11539.8 EGG41984.1 - 0.038 13.5 0.4 0.089 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) NAD_binding_3 PF03447.16 EGG41984.1 - 0.055 14.1 0.1 0.96 10.1 0.0 2.2 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Trm112p PF03966.16 EGG41985.1 - 6.9e-08 33.0 0.7 1.6e-07 31.8 0.3 1.8 2 1 0 2 2 2 1 Trm112p-like protein Cys_rich_KTR PF14205.6 EGG41985.1 - 0.058 13.2 0.4 0.12 12.2 0.4 1.6 1 1 0 1 1 1 0 Cysteine-rich KTR zf-RING_7 PF02591.15 EGG41985.1 - 0.12 12.5 0.0 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain Hexapep PF00132.24 EGG41986.1 - 3.4e-27 93.1 22.3 1.8e-11 43.2 1.4 4.3 3 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGG41986.1 - 2.8e-19 68.5 13.5 1.4e-11 43.9 3.4 4.5 5 0 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase RuvX PF03652.15 EGG41986.1 - 0.14 12.6 0.2 0.18 12.2 0.2 1.1 1 0 0 1 1 1 0 Holliday junction resolvase DUF4954 PF16314.5 EGG41986.1 - 2.3 6.2 5.4 4.6 5.2 3.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Glycos_transf_4 PF00953.21 EGG41988.1 - 1.7e-26 93.1 15.1 1.7e-26 93.1 15.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2254 PF10011.9 EGG41988.1 - 0.16 10.7 3.6 0.095 11.5 0.9 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF3043 PF11241.8 EGG41988.1 - 0.34 10.9 1.9 6.3 6.8 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) DEAD PF00270.29 EGG41989.1 - 4.2e-26 91.8 0.1 2e-25 89.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG41989.1 - 5.1e-13 49.4 0.2 1.5e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EGG41989.1 - 5.8e-12 46.0 0.8 2.5e-11 44.0 0.8 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.31 EGG41989.1 - 1.1e-11 45.0 2.8 4.9e-10 39.7 0.3 3.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HHH_2 PF12826.7 EGG41989.1 - 2.3e-06 27.6 1.5 0.00018 21.5 0.0 3.3 3 0 0 3 3 3 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 EGG41989.1 - 2.8e-06 27.0 0.0 8.7e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda ATPase_2 PF01637.18 EGG41989.1 - 0.0015 18.5 0.3 0.0015 18.5 0.3 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DUF4332 PF14229.6 EGG41989.1 - 0.015 15.5 0.0 0.062 13.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) T2SSE PF00437.20 EGG41989.1 - 0.033 13.3 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EGG41989.1 - 0.049 13.2 0.0 0.79 9.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain RNA_pol_A_CTD PF03118.15 EGG41989.1 - 0.059 13.1 1.6 0.14 11.9 0.1 2.5 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain DnaB_C PF03796.15 EGG41989.1 - 0.098 12.0 0.6 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HHH_8 PF14716.6 EGG41989.1 - 0.13 12.6 0.2 2.8 8.4 0.2 2.9 1 1 1 2 2 2 0 Helix-hairpin-helix domain MCM PF00493.23 EGG41990.1 - 4.3e-94 313.8 0.0 6.2e-94 313.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG41990.1 - 1.6e-35 121.7 0.1 2.8e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG41990.1 - 1.8e-23 82.8 1.3 3.7e-23 81.8 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG41990.1 - 7.4e-10 39.4 2.0 1.1e-09 38.8 0.3 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 EGG41990.1 - 1.6e-06 28.2 0.0 2.3e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGG41990.1 - 2.8e-06 26.9 0.0 0.0002 20.8 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGG41990.1 - 0.00081 19.3 0.0 0.0026 17.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGG41990.1 - 0.075 12.7 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG41990.1 - 0.17 12.3 0.7 4.8 7.5 0.0 3.0 3 1 0 4 4 4 0 AAA ATPase domain Sld5 PF05916.11 EGG41991.1 - 7.8e-09 36.0 1.4 1.2e-08 35.4 1.4 1.2 1 0 0 1 1 1 1 GINS complex protein DUF620 PF04788.12 EGG41991.1 - 0.044 13.2 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) DNA_pol3_delta2 PF13177.6 EGG41992.1 - 9.1e-17 61.3 0.2 7.8e-13 48.5 0.2 2.5 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EGG41992.1 - 6.8e-13 49.2 0.9 1.3e-12 48.2 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGG41992.1 - 1.2e-10 41.7 1.6 1.8e-10 41.0 0.6 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 EGG41992.1 - 4.5e-05 23.3 0.2 0.00014 21.7 0.2 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EGG41992.1 - 4.9e-05 23.8 0.1 0.00022 21.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGG41992.1 - 0.00011 21.9 0.0 0.00031 20.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EGG41992.1 - 0.00033 20.6 0.1 0.0035 17.3 0.0 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EGG41992.1 - 0.00036 20.8 0.2 0.0009 19.5 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_3 PF07726.11 EGG41992.1 - 0.0004 20.2 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG41992.1 - 0.00041 20.6 1.6 0.11 12.8 0.0 2.7 2 1 1 3 3 3 2 AAA domain TniB PF05621.11 EGG41992.1 - 0.0038 16.7 0.0 0.53 9.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein ResIII PF04851.15 EGG41992.1 - 0.0053 16.8 0.3 0.19 11.7 0.0 2.5 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EGG41992.1 - 0.0065 15.9 0.0 0.53 9.6 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI PTPlike_phytase PF14566.6 EGG41992.1 - 0.0074 16.4 0.3 0.069 13.3 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate PhoH PF02562.16 EGG41992.1 - 0.019 14.4 0.2 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 EGG41992.1 - 0.023 14.5 0.9 1.3 8.8 0.1 2.7 1 1 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 EGG41992.1 - 0.047 12.7 0.2 0.84 8.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGG41992.1 - 0.051 13.3 2.3 1.3 8.7 2.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGG41992.1 - 0.1 12.6 0.6 1.1 9.2 0.6 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EGG41992.1 - 0.13 12.6 0.8 3.2 8.1 0.1 2.6 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 EGG41992.1 - 0.84 9.7 5.0 19 5.3 4.9 2.2 1 1 0 1 1 1 0 Helicase HerA, central domain HATPase_c PF02518.26 EGG41993.1 - 6.8e-22 78.1 3.3 7.4e-22 78.0 0.3 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PorA PF11271.8 EGG41993.1 - 6.1e-14 52.0 0.1 1.1e-13 51.1 0.1 1.4 1 1 0 1 1 1 1 Porin PorA HATPase_c_5 PF14501.6 EGG41993.1 - 7.3e-08 32.2 0.6 3.6e-06 26.8 0.1 2.6 2 0 0 2 2 2 1 GHKL domain HisKA PF00512.25 EGG41993.1 - 8.8e-08 32.1 0.0 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGG41993.1 - 0.00014 21.7 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG41993.1 - 0.00022 21.2 0.0 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Fer4_10 PF13237.6 EGG41995.1 - 3.1e-08 33.6 5.2 2.1e-07 31.0 5.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EGG41995.1 - 3.5e-08 32.9 12.2 0.00025 20.7 2.7 2.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 EGG41995.1 - 6.2e-08 32.7 4.7 0.0018 18.4 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGG41995.1 - 6.3e-08 33.1 16.2 5.8e-06 26.8 9.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG41995.1 - 1.6e-07 31.7 12.9 9.3e-07 29.2 6.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGG41995.1 - 1.1e-06 29.4 5.4 2.7e-06 28.2 5.5 1.6 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EGG41995.1 - 2.1e-06 27.8 6.9 1.6e-05 24.9 7.1 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGG41995.1 - 7.4e-06 25.8 9.6 0.021 14.9 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGG41995.1 - 2.6e-05 24.6 3.1 7.1e-05 23.3 3.4 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG41995.1 - 0.00061 19.7 13.9 0.0036 17.3 0.9 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 EGG41995.1 - 0.0014 18.8 8.8 0.012 15.9 6.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EGG41995.1 - 0.0032 18.0 9.3 0.13 12.8 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 EGG41995.1 - 0.0046 17.8 0.5 4 8.3 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EGG41995.1 - 0.0086 16.5 10.7 0.29 11.7 0.3 2.6 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 EGG41995.1 - 0.33 12.0 13.7 3.5 8.8 5.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 EGG41995.1 - 2.2 9.0 12.0 0.39 11.5 1.3 2.7 3 1 0 3 3 2 0 4Fe-4S single cluster domain Fer4 PF00037.27 EGG41996.1 - 9.3e-10 37.9 11.9 6.6e-06 25.7 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGG41996.1 - 1.1e-09 38.7 2.6 6.9e-05 23.4 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGG41996.1 - 5e-08 33.8 3.9 0.00031 21.6 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EGG41996.1 - 7.6e-08 32.4 15.3 4.3e-07 29.9 5.1 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG41996.1 - 2.4e-07 30.8 6.1 1.2e-06 28.5 6.4 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EGG41996.1 - 4.6e-07 29.9 4.5 0.00089 19.3 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG41996.1 - 7.4e-07 29.5 0.6 0.016 15.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGG41996.1 - 6.3e-06 26.0 12.5 0.011 15.8 3.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 EGG41996.1 - 0.00018 21.9 8.1 0.03 14.9 0.1 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 EGG41996.1 - 0.00048 20.4 6.0 0.037 14.5 1.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 EGG41996.1 - 0.00056 20.1 5.9 0.00065 19.9 4.2 1.9 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG41996.1 - 0.00083 19.3 11.6 0.057 13.5 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGG41996.1 - 0.0016 18.9 5.9 0.097 13.2 7.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 EGG41996.1 - 0.0045 17.7 8.1 0.028 15.1 0.3 2.6 3 0 0 3 3 2 2 4Fe-4S single cluster domain Fer4_22 PF17179.4 EGG41996.1 - 0.012 16.5 0.6 6.2 7.7 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGG41996.1 - 0.082 13.9 14.9 1.8 9.7 6.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain eIF-6 PF01912.18 EGG41997.1 - 7.4e-63 211.5 1.3 8.9e-63 211.3 1.3 1.1 1 0 0 1 1 1 1 eIF-6 family tRNA-synt_His PF13393.6 EGG41998.1 - 3.1e-45 154.8 0.0 4e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EGG41998.1 - 9.8e-14 51.7 0.3 6.9e-13 49.0 0.2 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG41998.1 - 1.7e-09 37.7 0.3 4.5e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 EGG41998.1 - 0.0024 17.4 0.0 0.0066 16.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) RcpB PF16971.5 EGG41998.1 - 0.37 10.7 3.8 0.22 11.4 0.4 2.0 2 0 0 2 2 2 0 Rough colony protein B, tight adherence - tad - subunit FGAR-AT_N PF18076.1 EGG41999.1 - 3.3 7.7 7.6 38 4.3 1.3 3.7 2 2 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Archease PF01951.16 EGG42000.1 - 6e-30 104.3 1.1 6.6e-30 104.2 1.1 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) RdgC PF04381.12 EGG42000.1 - 0.028 13.7 0.2 0.035 13.4 0.2 1.1 1 0 0 1 1 1 0 Putative exonuclease, RdgC YbjQ_1 PF01906.17 EGG42000.1 - 0.029 15.0 0.0 0.049 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal-binding AsnC_trans_reg PF01037.21 EGG42001.1 - 1.6e-12 47.2 0.1 1.8e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 EGG42001.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 NapD protein GYD PF08734.11 EGG42001.1 - 0.05 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 GYD domain Copper-bind PF00127.20 EGG42002.1 - 1.7e-07 31.6 0.1 5.1e-06 26.9 0.1 2.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EGG42002.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain Calreticulin PF00262.18 EGG42002.1 - 0.00068 18.6 22.7 0.0049 15.8 8.6 2.3 1 1 1 2 2 2 2 Calreticulin family Bep_C_terminal PF17841.1 EGG42002.1 - 0.0011 19.1 3.4 0.098 12.9 0.2 2.9 1 1 1 2 2 2 2 BID domain of Bartonella effector protein (Bep) DUF1043 PF06295.12 EGG42002.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Response_reg PF00072.24 EGG42004.1 - 2.4e-20 72.8 0.3 2.7e-20 72.6 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Thioredoxin_8 PF13905.6 EGG42004.1 - 0.022 15.1 0.1 0.039 14.3 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like HATPase_c PF02518.26 EGG42005.1 - 6.5e-21 74.9 1.3 1.4e-20 73.8 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PorA PF11271.8 EGG42005.1 - 1.3e-16 60.8 0.0 6.1e-16 58.6 0.0 2.0 1 1 0 1 1 1 1 Porin PorA HisKA PF00512.25 EGG42005.1 - 3.7e-11 42.9 0.0 7.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EGG42005.1 - 1.3e-09 37.9 0.4 3.1e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 EGG42005.1 - 0.00018 21.3 0.1 0.0004 20.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG42005.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF898 PF05987.13 EGG42005.1 - 0.058 12.4 0.3 2.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Glucos_trans_II PF14264.6 EGG42005.1 - 0.17 11.2 2.2 0.74 9.1 0.1 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII P-II PF00543.22 EGG42006.1 - 0.00066 20.3 0.1 0.00072 20.1 0.1 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 EGG42006.1 - 0.0032 17.6 0.0 0.0081 16.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3240) DUF190 PF02641.15 EGG42006.1 - 0.0053 17.1 0.0 0.0093 16.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized ACR, COG1993 Sbt_1 PF05982.12 EGG42007.1 - 7.3e-93 311.2 21.6 8.4e-93 311.0 21.6 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily DUF92 PF01940.16 EGG42007.1 - 0.0073 15.7 6.8 0.65 9.4 0.0 2.5 1 1 0 2 2 2 2 Integral membrane protein DUF92 DUF1772 PF08592.11 EGG42007.1 - 0.027 14.8 3.9 2.7 8.3 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF1059 PF06348.11 EGG42008.1 - 4.4e-05 23.6 0.1 6.6e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Nas2_N PF18265.1 EGG42008.1 - 0.14 12.1 1.1 4.9 7.2 0.1 2.1 1 1 1 2 2 2 0 Nas2 N_terminal domain CopG_antitoxin PF12441.8 EGG42010.1 - 0.00022 21.7 0.0 0.00044 20.7 0.0 1.5 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system HTH_IclR PF09339.10 EGG42011.1 - 0.00032 20.4 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 EGG42011.1 - 0.0006 19.8 0.0 0.00077 19.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 EGG42011.1 - 0.0086 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.11 EGG42011.1 - 0.021 14.6 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Hpr_kinase_N PF02603.16 EGG42011.1 - 0.025 14.6 0.3 0.034 14.2 0.3 1.2 1 0 0 1 1 1 0 HPr Serine kinase N terminus Sarcoglycan_1 PF04790.13 EGG42011.1 - 0.034 13.5 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Aminotran_3 PF00202.21 EGG42012.1 - 1.5e-115 386.2 0.0 1.8e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG42012.1 - 0.0011 18.2 0.0 0.0023 17.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DUF2931 PF11153.8 EGG42012.1 - 0.062 13.0 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) HTH_AsnC-type PF13404.6 EGG42013.1 - 1.2e-13 50.7 0.0 2.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EGG42013.1 - 1e-12 47.4 0.2 1.7e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 EGG42013.1 - 3.4e-11 42.9 0.2 5.3e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 EGG42013.1 - 0.0015 18.4 0.4 0.0042 17.0 0.1 1.9 2 0 0 2 2 2 1 HTH domain NapD PF03927.13 EGG42013.1 - 0.0024 17.9 1.6 0.0056 16.7 1.0 1.8 1 1 0 1 1 1 1 NapD protein MarR_2 PF12802.7 EGG42013.1 - 0.0027 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 EGG42013.1 - 0.0036 17.1 0.0 0.013 15.4 0.0 1.9 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family ACT_4 PF13291.6 EGG42013.1 - 0.0049 17.4 1.1 2.7 8.6 0.2 2.4 2 0 0 2 2 2 2 ACT domain DUF2774 PF11242.8 EGG42013.1 - 0.0092 16.2 0.3 0.17 12.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2774) DDRGK PF09756.9 EGG42013.1 - 0.0092 15.6 2.8 0.035 13.7 0.2 2.1 2 0 0 2 2 2 1 DDRGK domain MarR PF01047.22 EGG42013.1 - 0.011 15.6 0.3 0.027 14.4 0.1 1.7 2 0 0 2 2 2 0 MarR family Sigma70_r4 PF04545.16 EGG42013.1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 SCO1-SenC PF02630.14 EGG42013.1 - 0.026 14.4 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 SCO1/SenC TrmB PF01978.19 EGG42013.1 - 0.028 14.3 1.2 0.45 10.4 0.1 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Stk19 PF10494.9 EGG42013.1 - 0.044 13.5 0.3 0.047 13.4 0.3 1.3 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 HTH_IclR PF09339.10 EGG42013.1 - 0.045 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_DeoR PF08220.12 EGG42013.1 - 0.048 13.4 0.4 0.19 11.5 0.1 2.0 2 1 1 3 3 3 0 DeoR-like helix-turn-helix domain Mga PF05043.13 EGG42013.1 - 0.05 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_9 PF08221.11 EGG42013.1 - 0.054 13.6 0.1 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RTP PF02334.16 EGG42013.1 - 0.068 13.8 0.1 0.1 13.2 0.1 1.3 1 0 0 1 1 1 0 Replication terminator protein HMGL-like PF00682.19 EGG42014.1 - 3.2e-66 223.6 0.0 4.2e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Radical_SAM PF04055.21 EGG42014.1 - 0.045 14.1 0.4 0.17 12.2 0.1 2.2 3 1 0 3 3 3 0 Radical SAM superfamily zinc_ribbon_4 PF13717.6 EGG42015.1 - 3.4e-06 26.9 3.7 0.0022 17.9 1.3 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zf-RING_7 PF02591.15 EGG42015.1 - 3.6e-05 23.9 0.4 0.0041 17.3 0.1 2.2 2 0 0 2 2 2 1 C4-type zinc ribbon domain RNA_POL_M_15KD PF02150.16 EGG42015.1 - 8.4e-05 22.4 0.4 0.34 10.8 0.1 2.1 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.12 EGG42015.1 - 0.00013 21.8 3.0 0.0018 18.2 3.8 2.0 1 1 1 2 2 2 2 PhnA Zinc-Ribbon zf_UBZ PF18439.1 EGG42015.1 - 0.00039 20.0 2.3 0.43 10.2 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 EGG42015.1 - 0.00048 20.0 2.4 0.00084 19.2 2.4 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 HypA PF01155.19 EGG42015.1 - 0.0012 18.8 0.4 0.0014 18.6 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EGG42015.1 - 0.0013 18.8 2.1 0.002 18.2 2.1 1.3 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EGG42015.1 - 0.0019 17.7 1.0 0.0026 17.3 1.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 EGG42015.1 - 0.0028 17.9 0.9 0.0042 17.3 0.9 1.3 1 0 0 1 1 1 1 zinc-ribbon zf-C4_Topoisom PF01396.19 EGG42015.1 - 0.0034 17.1 0.9 0.27 11.0 0.0 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_5 PF13719.6 EGG42015.1 - 0.0055 16.4 2.0 0.11 12.3 0.0 2.5 3 0 0 3 3 3 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGG42015.1 - 0.0077 15.6 0.8 0.13 11.7 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain IBR PF01485.21 EGG42015.1 - 0.0085 16.3 0.5 0.011 16.0 0.5 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-HYPF PF07503.12 EGG42015.1 - 0.0086 15.8 2.3 0.059 13.2 2.3 1.9 1 1 0 1 1 1 1 HypF finger DZR PF12773.7 EGG42015.1 - 0.02 14.9 1.0 0.033 14.2 1.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EGG42015.1 - 0.025 14.6 0.9 0.05 13.6 0.9 1.5 1 1 0 1 1 1 0 zinc-ribbons DNA_RNApol_7kD PF03604.13 EGG42015.1 - 0.026 14.2 2.9 0.083 12.6 2.9 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 EGG42015.1 - 0.031 14.0 1.4 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain BssC_TutF PF08201.11 EGG42015.1 - 0.039 14.0 3.1 0.061 13.3 0.3 2.0 1 1 1 2 2 2 0 BssC/TutF protein ADK_lid PF05191.14 EGG42015.1 - 0.042 13.8 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid PTP2 PF17022.5 EGG42015.1 - 0.053 13.1 0.6 0.053 13.1 0.6 1.0 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia C1_1 PF00130.22 EGG42015.1 - 0.053 13.4 0.3 0.11 12.4 0.3 1.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1451 PF07295.11 EGG42015.1 - 0.074 13.1 0.7 0.086 12.9 0.7 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 EGG42015.1 - 0.077 12.7 3.2 0.67 9.7 3.2 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain UPF0547 PF10571.9 EGG42015.1 - 0.08 13.0 4.8 2 8.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CpXC PF14353.6 EGG42015.1 - 0.12 12.4 1.6 1.3 9.1 0.2 2.0 1 1 1 2 2 2 0 CpXC protein DpnI PF06044.12 EGG42015.1 - 0.14 11.8 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Dam-replacing family zf-H2C2_2 PF13465.6 EGG42015.1 - 0.18 12.3 0.5 2.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain DiS_P_DiS PF06750.13 EGG42015.1 - 0.2 11.8 0.8 1.5 9.0 0.3 1.9 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-ACC PF17848.1 EGG42015.1 - 0.4 10.8 5.3 7.9 6.7 0.4 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_6 PF13912.6 EGG42015.1 - 1.1 9.3 0.2 1.1 9.3 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-dskA_traR PF01258.17 EGG42015.1 - 1.7 8.7 6.6 6.3 6.8 6.7 1.8 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger RimK PF08443.11 EGG42016.1 - 2e-30 105.8 0.0 2.4e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EGG42016.1 - 1.5e-08 34.2 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 EGG42016.1 - 3.2e-07 30.5 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGG42016.1 - 0.00036 19.9 0.1 0.4 9.9 0.0 2.4 1 1 2 3 3 3 2 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.17 EGG42016.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_YheCD PF14398.6 EGG42016.1 - 0.058 12.6 0.0 7.9 5.6 0.0 2.3 1 1 1 2 2 2 0 YheC/D like ATP-grasp ATP-grasp_5 PF13549.6 EGG42016.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 EGG42016.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain Peptidase_M20 PF01546.28 EGG42017.1 - 2.5e-28 99.2 0.7 4.5e-28 98.4 0.7 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG42017.1 - 2.6e-11 43.4 0.0 5.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 EGG42017.1 - 2.5e-05 23.5 0.6 0.055 12.5 0.1 2.4 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 EGG42017.1 - 0.0023 17.6 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 TP_methylase PF00590.20 EGG42018.1 - 1.1e-19 71.2 0.0 3.8e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF357 PF04010.13 EGG42018.1 - 3e-13 49.7 0.2 9.9e-13 48.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF357) RE_HaeIII PF09556.10 EGG42018.1 - 0.052 12.6 0.1 0.08 12.0 0.1 1.3 1 0 0 1 1 1 0 HaeIII restriction endonuclease Ala_racemase_C PF00842.21 EGG42018.1 - 0.077 12.8 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain DUF1661 PF07877.11 EGG42018.1 - 0.78 9.5 2.0 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) CTP_transf_like PF01467.26 EGG42019.1 - 7.9e-13 48.8 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EGG42019.1 - 0.077 12.9 0.3 0.54 10.1 0.1 2.1 1 1 1 2 2 2 0 FAD synthetase Period_C PF12114.8 EGG42019.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CTP-dep_RFKase PF01982.16 EGG42020.1 - 3.7e-41 140.0 0.1 5.5e-41 139.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF120 Phage_rep_O PF04492.13 EGG42020.1 - 0.033 14.8 1.8 1.6 9.4 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage replication protein O HicB PF05534.12 EGG42020.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 HicB family Toprim_4 PF13662.6 EGG42021.1 - 1.1e-07 32.2 0.4 2.5e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 EGG42021.1 - 2.6e-05 24.6 0.0 5.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 EGG42021.1 - 0.057 13.6 0.2 0.17 12.1 0.2 1.9 1 1 0 1 1 1 0 Toprim domain Fe-S_biosyn PF01521.20 EGG42022.1 - 7.5e-22 77.6 0.0 8.4e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ECH_1 PF00378.20 EGG42023.1 - 4.2e-69 232.6 1.0 4.8e-69 232.5 1.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG42023.1 - 2.5e-38 132.4 0.9 8e-35 120.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4362 PF14275.6 EGG42023.1 - 0.074 13.3 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) ATP-grasp_5 PF13549.6 EGG42024.1 - 3.6e-67 226.1 0.7 5.6e-67 225.4 0.7 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EGG42024.1 - 7.8e-49 165.0 0.2 1.8e-48 163.8 0.2 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGG42024.1 - 7e-24 84.6 0.1 2.3e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 EGG42024.1 - 5.5e-08 32.6 0.8 1.1e-07 31.6 0.8 1.5 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 EGG42024.1 - 1.1e-07 32.4 1.7 5.3e-07 30.2 0.2 3.0 3 0 0 3 3 3 1 CoA binding domain ATP-grasp PF02222.22 EGG42024.1 - 0.015 14.9 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain GATase PF00117.28 EGG42025.1 - 9.6e-22 77.7 0.0 1.4e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG42025.1 - 1.6e-06 28.1 0.2 2e-05 24.5 0.0 2.4 2 1 0 2 2 2 1 Peptidase C26 HTS PF04204.16 EGG42025.1 - 2.3e-05 23.5 0.0 4.4e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 Homoserine O-succinyltransferase GATase_3 PF07685.14 EGG42025.1 - 0.012 15.2 0.5 0.016 14.8 0.0 1.5 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EGG42025.1 - 0.054 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family INTS5_N PF14837.6 EGG42025.1 - 0.12 12.0 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Toprim PF01751.22 EGG42026.1 - 0.00018 21.7 0.1 0.0016 18.6 0.1 2.0 1 1 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 EGG42026.1 - 0.00038 20.9 0.0 0.0038 17.7 0.0 2.1 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 EGG42026.1 - 0.0041 17.5 0.0 0.0054 17.1 0.0 1.3 1 1 0 1 1 1 1 Toprim-like ELFV_dehydrog PF00208.21 EGG42027.1 - 2e-67 227.5 1.9 2.7e-67 227.0 1.9 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EGG42027.1 - 1.4e-47 160.8 0.0 2.4e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Proteasome PF00227.26 EGG42028.1 - 6.2e-48 162.8 2.1 7.8e-48 162.5 2.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG42028.1 - 1.6e-12 46.8 1.7 1.3e-10 40.8 0.2 2.8 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature Ubie_methyltran PF01209.18 EGG42029.1 - 2.8e-17 62.9 0.0 3.3e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGG42029.1 - 6.5e-12 45.9 0.0 9.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG42029.1 - 1.3e-11 45.0 0.0 1.9e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG42029.1 - 4.5e-07 29.8 0.0 5.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG42029.1 - 5.3e-07 29.5 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG42029.1 - 2.6e-05 24.9 0.0 4.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG42029.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MFS_1 PF07690.16 EGG42030.1 - 2.5e-40 138.5 57.4 2.2e-27 95.9 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGG42030.1 - 9.3e-14 51.5 17.8 1.2e-13 51.1 17.8 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EGG42030.1 - 0.0016 17.0 14.0 0.011 14.2 14.0 2.0 1 1 0 1 1 1 1 Transmembrane secretion effector MASE2 PF05230.11 EGG42030.1 - 0.0064 16.5 3.4 0.0068 16.5 0.3 2.6 2 1 0 2 2 2 1 MASE2 domain Phage_holin_8 PF16931.5 EGG42030.1 - 0.0076 16.2 3.3 0.017 15.1 0.1 2.8 3 0 0 3 3 3 1 Putative phage holin OATP PF03137.20 EGG42030.1 - 0.051 11.9 16.9 0.034 12.4 1.6 3.7 1 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family P-II PF00543.22 EGG42031.1 - 3.1e-19 69.5 0.9 7.9e-19 68.2 0.9 1.6 1 1 0 1 1 1 1 Nitrogen regulatory protein P-II MttA_Hcf106 PF02416.16 EGG42032.1 - 4.3e-07 29.2 0.1 5.5e-07 28.8 0.1 1.3 1 1 0 1 1 1 1 mttA/Hcf106 family DLP_helical PF18709.1 EGG42032.1 - 0.00029 20.1 0.6 0.00034 19.9 0.6 1.0 1 0 0 1 1 1 1 Dynamin-like helical domain Phage_Mu_Gam PF07352.12 EGG42032.1 - 0.0011 18.9 0.1 0.0013 18.7 0.1 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein COG2 PF06148.11 EGG42032.1 - 0.045 13.8 0.1 0.068 13.3 0.1 1.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3852 PF12963.7 EGG42032.1 - 0.067 13.5 0.1 0.2 12.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) N6_N4_Mtase PF01555.18 EGG42033.1 - 3.1e-36 125.3 4.5 3.7e-36 125.0 4.5 1.1 1 0 0 1 1 1 1 DNA methylase UPF0020 PF01170.18 EGG42033.1 - 0.00019 21.2 0.0 0.073 12.7 0.0 2.4 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 N6-adenineMlase PF10237.9 EGG42033.1 - 0.0034 17.2 0.1 0.0072 16.1 0.0 1.7 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase MTS PF05175.14 EGG42033.1 - 0.16 11.5 0.0 0.8 9.2 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase small domain DEAD PF00270.29 EGG42034.1 - 2.8e-34 118.4 0.1 8.3e-34 116.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG42034.1 - 6.9e-18 65.0 2.5 2.2e-13 50.5 0.5 3.5 4 0 0 4 4 4 2 Helicase conserved C-terminal domain DUF1998 PF09369.10 EGG42034.1 - 1.9e-09 38.2 0.1 5.1e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) SNF2_N PF00176.23 EGG42034.1 - 0.0099 14.6 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Adenine_glyco PF03352.13 EGG42034.1 - 0.13 12.0 0.7 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 Methyladenine glycosylase adh_short PF00106.25 EGG42035.1 - 2.6e-50 170.6 0.1 3.6e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG42035.1 - 3.7e-37 128.1 0.0 5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG42035.1 - 1.2e-09 38.3 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGG42035.1 - 1.1e-06 28.3 0.1 7.8e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EGG42035.1 - 0.021 14.4 0.1 0.077 12.5 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family Topoisom_I PF01028.20 EGG42036.1 - 3.2e-70 236.0 11.6 3.2e-70 236.0 11.6 2.5 2 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGG42036.1 - 4.7e-69 232.2 6.1 4.7e-69 232.2 6.1 2.9 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGG42036.1 - 1.1e-21 76.5 1.5 1.1e-21 76.5 1.5 4.5 5 2 0 5 5 5 1 C-terminal topoisomerase domain GerD PF17898.1 EGG42037.1 - 3.5e-05 23.7 43.8 0.00021 21.2 20.5 2.9 1 1 2 3 3 3 2 Spore germination GerD central core domain STI1 PF17830.1 EGG42037.1 - 0.00057 19.8 16.0 0.00057 19.8 16.0 3.5 2 1 1 3 3 3 2 STI1 domain PutA_N PF18083.1 EGG42037.1 - 0.0021 18.0 11.0 0.16 12.0 2.8 2.5 2 1 0 2 2 2 2 Proline utilization A N-terminal domain DUF2206 PF09971.9 EGG42037.1 - 0.0034 16.2 1.6 0.004 16.0 1.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) DUF3172 PF11371.8 EGG42037.1 - 0.04 13.6 0.1 0.091 12.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3172) Sulfotransfer_3 PF13469.6 EGG42037.1 - 0.053 13.9 4.0 0.047 14.1 2.9 1.4 1 1 0 1 1 1 0 Sulfotransferase family DUF3413 PF11893.8 EGG42037.1 - 0.059 12.5 0.6 0.088 12.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) AbiH PF14253.6 EGG42037.1 - 0.11 12.4 3.2 0.13 12.1 3.2 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF1221 PF06760.11 EGG42037.1 - 0.14 11.6 3.5 0.17 11.4 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Bep_C_terminal PF17841.1 EGG42037.1 - 0.2 11.9 5.8 2.7 8.3 0.1 2.5 1 1 1 2 2 2 0 BID domain of Bartonella effector protein (Bep) Methyltransf_31 PF13847.6 EGG42037.1 - 0.52 10.1 2.6 0.87 9.4 2.6 1.5 1 1 0 1 1 1 0 Methyltransferase domain TetR_C_28 PF17937.1 EGG42037.1 - 1.3 9.5 4.5 7.9 7.0 0.1 2.9 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PEP-utilisers_N PF05524.13 EGG42037.1 - 7.4 6.8 6.4 18 5.5 0.6 2.7 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Glyco_hydro_31 PF01055.26 EGG42039.1 - 0.013 14.8 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 GPI2 PF06432.11 EGG42041.1 - 0.056 12.9 10.0 0.065 12.7 10.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4231 PF14015.6 EGG42041.1 - 0.29 11.6 9.5 0.1 13.0 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) MerC PF03203.14 EGG42041.1 - 0.97 9.9 14.9 3.5 8.1 14.8 1.9 1 1 0 1 1 1 0 MerC mercury resistance protein DUF2070 PF09843.9 EGG42041.1 - 4.9 5.3 17.3 6 5.0 17.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HTH_24 PF13412.6 EGG42042.1 - 5.3e-12 45.1 0.5 9.8e-07 28.2 0.0 3.2 3 1 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 EGG42042.1 - 1.7e-07 31.0 0.2 0.015 15.1 0.0 2.9 2 1 1 3 3 3 2 Bacterial regulatory protein, arsR family MarR PF01047.22 EGG42042.1 - 2e-06 27.6 0.0 9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 EGG42042.1 - 6.1e-06 26.3 0.0 0.0018 18.4 0.0 2.1 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR_2 PF12802.7 EGG42042.1 - 0.00013 21.7 0.0 0.0009 19.1 0.0 2.0 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 EGG42042.1 - 0.0036 17.1 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EGG42042.1 - 0.013 15.3 0.0 5 7.0 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_45 PF14947.6 EGG42042.1 - 0.018 15.0 0.1 6.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix TFIIE_alpha PF02002.17 EGG42042.1 - 0.047 13.5 0.1 0.28 11.1 0.0 2.1 1 1 1 2 2 2 0 TFIIE alpha subunit GSDH PF07995.11 EGG42044.1 - 4.8e-96 321.9 0.1 6.4e-96 321.5 0.1 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Proteasome_A_N PF10584.9 EGG42044.1 - 0.031 13.9 4.2 0.2 11.3 0.1 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF5122 PF17164.4 EGG42044.1 - 0.088 13.1 2.5 0.92 9.9 2.3 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller SGL PF08450.12 EGG42044.1 - 0.12 11.9 0.0 23 4.5 0.0 2.9 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region HATPase_c PF02518.26 EGG42045.1 - 4.4e-23 81.9 0.2 1e-22 80.8 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 EGG42045.1 - 1.8e-13 50.5 0.0 2.9e-11 43.4 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGG42045.1 - 2.2e-11 43.9 0.1 5.1e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 EGG42045.1 - 2.1e-09 37.3 0.2 5e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EGG42045.1 - 8.9e-07 29.1 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGG42045.1 - 2.2e-06 27.9 0.0 4.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EGG42045.1 - 0.00019 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 EGG42045.1 - 0.00032 20.6 0.1 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 EGG42045.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG42045.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Cupredoxin_1 PF13473.6 EGG42046.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Cupredoxin-like domain Arch_flagellin PF01917.16 EGG42046.1 - 0.2 11.8 3.4 5.7 7.1 1.3 2.3 2 1 0 2 2 2 0 Archaebacterial flagellin ATG16 PF08614.11 EGG42048.1 - 0.0013 19.1 0.7 0.24 11.6 0.1 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DHR10 PF18595.1 EGG42048.1 - 0.011 15.8 2.3 0.79 9.8 0.2 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain z-alpha PF02295.17 EGG42048.1 - 0.034 14.2 2.1 0.33 11.0 0.1 2.7 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain DUF4140 PF13600.6 EGG42048.1 - 0.084 13.3 3.3 12 6.4 0.1 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF848 PF05852.11 EGG42048.1 - 0.088 12.9 0.8 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Gon7 PF08738.10 EGG42048.1 - 0.15 12.1 1.0 4.4 7.4 0.0 2.7 3 0 0 3 3 3 0 Gon7 family Prefoldin_2 PF01920.20 EGG42048.1 - 0.16 12.0 5.0 1.7 8.6 0.0 3.5 3 1 1 4 4 4 0 Prefoldin subunit FlxA PF14282.6 EGG42048.1 - 0.35 10.9 6.5 8 6.5 0.6 3.1 2 1 1 3 3 3 0 FlxA-like protein Ribosomal_L29 PF00831.23 EGG42048.1 - 1.4 8.9 6.1 22 5.1 0.1 3.6 2 2 1 3 3 3 0 Ribosomal L29 protein BST2 PF16716.5 EGG42048.1 - 1.9 9.1 5.1 9.6 6.9 0.1 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Csm1_N PF18504.1 EGG42048.1 - 2.1 8.8 5.7 5.6 7.4 0.2 3.4 2 2 1 3 3 3 0 Csm1 N-terminal domain Med9 PF07544.13 EGG42048.1 - 2.4 8.3 7.5 14 5.9 0.3 3.3 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Snapin_Pallidin PF14712.6 EGG42048.1 - 5.5 7.5 8.6 0.5 10.8 1.8 2.6 4 0 0 4 4 2 0 Snapin/Pallidin Rac1 PF09632.10 EGG42050.1 - 0.0022 17.2 0.3 0.0027 17.0 0.3 1.1 1 0 0 1 1 1 1 Rac1-binding domain FliD_C PF07195.12 EGG42050.1 - 0.0086 15.5 0.9 0.012 15.0 0.5 1.4 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Guanylate_cyc PF00211.20 EGG42052.1 - 1.8e-11 44.0 0.0 4.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HATPase_c_4 PF13749.6 EGG42052.1 - 0.011 15.8 0.0 7.5 6.8 0.0 4.6 4 1 0 4 4 4 0 Putative ATP-dependent DNA helicase recG C-terminal DUF2582 PF10771.9 EGG42052.1 - 0.081 13.1 0.1 21 5.4 0.0 4.4 5 0 0 5 5 5 0 Winged helix-turn-helix domain (DUF2582) BtrH_N PF14399.6 EGG42052.1 - 0.37 11.0 4.2 33 4.7 0.0 5.0 3 1 3 6 6 6 0 Butirosin biosynthesis protein H, N-terminal RNA_helicase PF00910.22 EGG42053.1 - 5.9e-05 23.4 0.0 0.00018 21.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EGG42053.1 - 0.0011 19.0 1.6 0.0013 18.7 0.4 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 EGG42053.1 - 0.0021 17.0 0.0 0.0045 15.9 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 EGG42053.1 - 0.0076 15.7 1.8 0.015 14.8 0.0 2.3 2 1 0 2 2 2 1 Poxvirus A32 protein ResIII PF04851.15 EGG42053.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EGG42053.1 - 0.071 13.7 0.2 0.29 11.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGG42053.1 - 0.13 11.6 0.0 0.62 9.4 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.6 EGG42053.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Glyco_hyd_101C PF17451.2 EGG42054.1 - 0.17 12.2 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain Caldesmon PF02029.15 EGG42055.1 - 0.25 10.1 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Caldesmon UDG PF03167.19 EGG42056.1 - 0.00022 21.2 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily CD4-extracel PF09191.10 EGG42056.1 - 0.13 12.7 0.2 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 CD4, extracellular SH3_2 PF07653.17 EGG42056.1 - 0.16 11.6 0.1 5.3 6.8 0.0 3.2 4 0 0 4 4 4 0 Variant SH3 domain CHAT PF12770.7 EGG42058.1 - 1e-22 80.9 0.0 1.4e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 EGG42058.1 - 0.00011 21.5 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 DUF3153 PF11353.8 EGG42058.1 - 0.016 14.8 0.3 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Lactamase_B PF00753.27 EGG42059.1 - 4.5e-05 23.5 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily zf-ribbon_3 PF13248.6 EGG42060.1 - 0.00043 19.6 5.2 0.00043 19.6 5.2 1.8 2 0 0 2 2 2 1 zinc-ribbon domain Cupredoxin_1 PF13473.6 EGG42060.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain DZR PF12773.7 EGG42060.1 - 0.0032 17.4 0.5 0.0075 16.3 0.5 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGG42060.1 - 0.018 15.8 0.2 0.031 15.0 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon family OrfB_Zn_ribbon PF07282.11 EGG42060.1 - 0.09 12.7 1.3 0.16 11.9 1.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2116 PF09889.9 EGG42060.1 - 0.14 12.1 0.9 0.29 11.2 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Prok-RING_1 PF14446.6 EGG42060.1 - 0.19 11.7 2.1 0.41 10.6 2.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HIT PF04438.16 EGG42060.1 - 0.41 10.6 1.9 0.82 9.6 1.9 1.5 1 0 0 1 1 1 0 HIT zinc finger zinc_ribbon_2 PF13240.6 EGG42060.1 - 2.8 7.8 9.5 0.14 11.9 4.0 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_C14 PF00656.22 EGG42061.1 - 1.8e-17 64.1 0.1 2.8e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Caspase domain TPR_1 PF00515.28 EGG42061.1 - 5.5e-16 57.6 0.2 3.9e-05 23.3 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42061.1 - 8.2e-16 56.8 0.1 0.00092 19.1 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG42061.1 - 5.1e-07 29.4 2.8 0.6 10.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG42061.1 - 8.3e-07 29.6 0.0 3.3e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG42061.1 - 9.5e-06 25.2 0.0 0.32 10.7 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EGG42061.1 - 4.9e-05 23.8 0.0 1 10.4 0.0 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42061.1 - 0.00011 22.7 0.0 0.016 15.7 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG42061.1 - 0.00033 21.1 0.0 3.2 8.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG42061.1 - 0.00056 20.1 0.0 0.0051 17.0 0.1 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C13 PF01650.18 EGG42061.1 - 0.033 13.7 0.1 0.13 11.7 0.0 2.0 2 1 1 3 3 3 0 Peptidase C13 family TPR_17 PF13431.6 EGG42061.1 - 0.045 14.1 1.7 24 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42061.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Raptor_N PF14538.6 EGG42061.1 - 0.079 12.9 0.9 1.8 8.5 0.1 2.9 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain TPR_9 PF13371.6 EGG42061.1 - 0.1 12.8 0.0 0.34 11.1 0.0 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 EGG42063.1 - 8.2e-13 48.4 0.1 1.1e-12 48.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4423 PF14394.6 EGG42064.1 - 3.8e-07 30.0 0.2 4.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 EGG42064.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 MarR family PCI PF01399.27 EGG42064.1 - 0.0013 19.2 0.6 0.024 15.1 0.1 2.4 2 1 0 2 2 2 1 PCI domain DUF1724 PF08350.10 EGG42064.1 - 0.0037 17.4 0.4 0.0097 16.0 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1724) HTH_24 PF13412.6 EGG42064.1 - 0.005 16.4 0.3 0.011 15.3 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 EGG42064.1 - 0.0059 16.4 0.3 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EGG42064.1 - 0.007 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EGG42064.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_45 PF14947.6 EGG42064.1 - 0.015 15.2 2.2 0.022 14.7 0.2 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix MarR PF01047.22 EGG42064.1 - 0.019 14.8 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 MarR family MotA_activ PF09114.10 EGG42064.1 - 0.022 14.9 0.7 0.056 13.6 0.1 2.0 2 1 0 2 2 2 0 Transcription factor MotA, activation domain HTH_Crp_2 PF13545.6 EGG42064.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain RuvB_C PF05491.13 EGG42064.1 - 0.061 13.2 0.6 0.15 11.9 0.6 1.7 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain TrmB PF01978.19 EGG42064.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Mrr_N PF14338.6 EGG42064.1 - 0.093 12.9 0.1 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 Mrr N-terminal domain HTH_27 PF13463.6 EGG42064.1 - 0.11 13.0 0.1 0.2 12.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain CdiA_C PF18451.1 EGG42064.1 - 2.2 8.5 9.3 0.91 9.8 0.2 2.9 2 1 1 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain Nitroreductase PF00881.24 EGG42065.1 - 1.9e-30 106.1 0.0 2.3e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EGG42065.1 - 2.5e-09 37.0 0.0 8.6e-06 25.5 0.1 2.2 1 1 1 2 2 2 2 Putative TM nitroreductase Peptidase_C14 PF00656.22 EGG42066.1 - 5.5e-20 72.4 0.2 1.1e-19 71.4 0.2 1.5 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 EGG42066.1 - 0.0002 21.0 0.1 0.00056 19.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase C13 family Plasmid_parti PF01672.16 EGG42066.1 - 0.1 13.2 1.0 0.43 11.2 0.5 2.4 2 0 0 2 2 2 0 Putative plasmid partition protein CHAT PF12770.7 EGG42067.1 - 4.5e-09 36.1 0.0 2.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 CHAT domain YuiB PF14068.6 EGG42068.1 - 0.069 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative membrane protein DUF11 PF01345.18 EGG42069.1 - 0.018 15.3 0.9 0.033 14.5 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF11 ASXH PF13919.6 EGG42069.1 - 0.019 15.0 2.3 0.019 15.0 2.3 1.7 2 0 0 2 2 2 0 Asx homology domain CARDB PF07705.11 EGG42069.1 - 0.051 13.8 2.8 0.12 12.7 2.8 1.6 1 0 0 1 1 1 0 CARDB Allexi_40kDa PF05549.11 EGG42069.1 - 0.097 12.2 2.1 0.19 11.2 2.1 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein OmpH PF03938.14 EGG42069.1 - 0.28 11.5 9.9 0.58 10.5 9.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HJURP_C PF12347.8 EGG42069.1 - 1.6 8.8 5.5 0.45 10.6 0.3 2.3 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF808 PF05661.12 EGG42070.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Peptidase_M48 PF01435.18 EGG42071.1 - 0.024 14.4 0.4 11 5.7 1.4 2.7 1 1 1 2 2 2 0 Peptidase family M48 tRNA-synt_2c PF01411.19 EGG42072.1 - 5.1e-83 279.4 0.0 5.1e-83 279.4 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGG42072.1 - 5.5e-15 55.2 0.9 1.7e-14 53.6 0.9 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGG42072.1 - 6.9e-08 33.0 9.3 6.9e-08 33.0 9.3 2.3 2 1 0 2 2 2 1 DHHA1 domain PVL_ORF50 PF07768.11 EGG42072.1 - 0.89 9.9 6.6 2.8 8.3 6.1 2.1 2 0 0 2 2 2 0 PVL ORF-50-like family ATP-synt_E PF05680.12 EGG42072.1 - 2.9 8.3 7.2 9.3 6.7 7.2 1.8 1 0 0 1 1 1 0 ATP synthase E chain tRNA-synt_1 PF00133.22 EGG42073.1 - 2.4e-55 188.0 2.6 1.3e-54 185.6 2.6 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGG42073.1 - 1.2e-24 86.8 0.2 2.6e-12 46.2 0.1 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGG42073.1 - 3.8e-21 75.6 0.8 8.3e-21 74.5 0.8 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGG42073.1 - 3.7e-11 42.9 2.1 6.3e-06 25.7 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EGG42073.1 - 9.3e-07 28.5 0.1 6.1e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Ubie_methyltran PF01209.18 EGG42074.1 - 7.1e-20 71.3 0.0 7.8e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGG42074.1 - 7.9e-17 61.8 0.0 1.3e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG42074.1 - 1.9e-15 57.0 0.0 2.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG42074.1 - 9.4e-15 55.0 0.0 1.5e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG42074.1 - 2.9e-12 47.2 0.0 5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG42074.1 - 7.3e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGG42074.1 - 4.3e-09 36.2 0.0 6.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGG42074.1 - 2.5e-08 33.7 0.0 6.7e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EGG42074.1 - 1.2e-05 24.9 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 EGG42074.1 - 2.2e-05 24.2 0.0 2.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 EGG42074.1 - 0.00023 20.2 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EGG42074.1 - 0.0031 16.9 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 EGG42074.1 - 0.025 15.6 0.0 0.039 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 EGG42074.1 - 0.025 14.6 0.0 0.17 11.8 0.0 2.3 3 1 0 3 3 3 0 Zinc-binding dehydrogenase Methyltransf_4 PF02390.17 EGG42074.1 - 0.032 13.7 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase GidB PF02527.15 EGG42074.1 - 0.042 13.2 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 EGG42074.1 - 0.055 12.5 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EGG42074.1 - 0.089 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DZR PF12773.7 EGG42075.1 - 0.0091 16.0 3.8 0.0091 16.0 3.8 2.1 1 1 1 2 2 2 1 Double zinc ribbon GDH_N PF12466.8 EGG42075.1 - 0.21 11.8 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal DUF983 PF06170.12 EGG42075.1 - 0.38 11.2 3.4 0.88 10.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF983) zinc_ribbon_2 PF13240.6 EGG42075.1 - 1.4 8.8 8.5 2.7 7.8 0.8 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 EGG42075.1 - 1.4 8.6 6.3 1.5 8.5 0.1 2.8 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RNA_POL_M_15KD PF02150.16 EGG42075.1 - 1.5 8.8 8.1 0.64 10.0 3.7 2.4 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nitroreductase PF00881.24 EGG42076.1 - 7.3e-34 117.3 0.0 9.6e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EGG42076.1 - 6.7e-12 45.4 0.3 3e-05 23.7 0.3 2.8 2 1 0 2 2 2 2 Putative TM nitroreductase DUF1951 PF09188.10 EGG42076.1 - 0.026 14.5 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) Zeta_toxin PF06414.12 EGG42076.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Trp_halogenase PF04820.14 EGG42077.1 - 4.1e-06 25.9 0.0 1.5e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_2 PF03446.15 EGG42077.1 - 0.00031 20.9 0.0 0.00086 19.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGG42077.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EGG42077.1 - 0.018 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGG42077.1 - 0.033 13.5 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Anth_synt_I_N PF04715.13 EGG42077.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region CxxCxxCC PF03692.15 EGG42078.1 - 9.5e-09 35.8 1.4 6e-08 33.3 1.4 2.1 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Ribosomal_S7 PF00177.21 EGG42080.1 - 2.6e-36 124.5 1.2 3.7e-36 124.0 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 EGG42081.1 - 2.4e-46 156.0 0.3 3.1e-46 155.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KH_2 PF07650.17 EGG42082.1 - 1.5e-18 66.3 2.7 2.5e-12 46.4 0.2 2.1 1 1 1 2 2 2 2 KH domain KH_4 PF13083.6 EGG42082.1 - 8.7e-11 41.6 0.5 0.00017 21.4 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 EGG42082.1 - 5.5e-08 32.8 3.1 2.1e-07 30.9 0.3 2.1 2 0 0 2 2 2 1 NusA-like KH domain KH_1 PF00013.29 EGG42082.1 - 0.0005 19.8 0.5 0.043 13.6 0.1 2.3 2 0 0 2 2 2 2 KH domain Ribosomal_L7Ae PF01248.26 EGG42083.1 - 1.1e-11 44.3 0.6 1.4e-11 44.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1694 PF07997.11 EGG42083.1 - 0.028 14.5 1.7 0.028 14.5 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) DUF5584 PF17822.1 EGG42083.1 - 0.044 13.2 0.1 0.045 13.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5584) TPR_1 PF00515.28 EGG42084.1 - 2e-19 68.5 0.3 1e-06 28.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42084.1 - 1.1e-16 59.5 0.0 0.0001 22.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG42084.1 - 2.4e-13 49.4 1.4 0.00091 19.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG42084.1 - 3.1e-11 42.6 1.2 0.00011 22.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG42084.1 - 3e-10 39.6 1.1 0.00012 21.7 0.3 3.2 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.6 EGG42084.1 - 4.9e-09 35.6 0.0 0.0021 18.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG42084.1 - 1.6e-07 31.5 0.0 0.1 12.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG42084.1 - 1.9e-06 28.2 0.0 0.81 10.7 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG42084.1 - 1.4e-05 25.7 0.0 0.13 12.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG42084.1 - 3.2e-05 23.7 0.2 0.0078 16.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42084.1 - 3.9e-05 23.6 0.1 0.45 10.6 0.0 3.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGG42084.1 - 0.0001 22.7 0.0 0.93 10.0 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.8 EGG42084.1 - 0.00098 18.1 0.0 0.046 12.6 0.0 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 EGG42084.1 - 0.073 13.7 0.1 3.8 8.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1425 PF07233.12 EGG42085.1 - 0.19 11.7 0.9 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1425) HCBP_related PF06594.11 EGG42085.1 - 0.86 9.6 4.8 7.8 6.5 0.1 4.3 3 1 1 4 4 4 0 Haemolysin-type calcium binding protein related domain LSM PF01423.22 EGG42086.1 - 6.4e-17 61.0 3.3 7.2e-17 60.8 3.3 1.0 1 0 0 1 1 1 1 LSM domain RNA_pol_Rpb1_1 PF04997.12 EGG42087.1 - 3.3e-93 312.5 0.0 1.5e-92 310.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGG42087.1 - 7.4e-84 281.3 1.7 1.7e-83 280.1 1.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGG42087.1 - 4.7e-73 244.9 0.0 7.9e-73 244.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGG42087.1 - 6.8e-35 120.3 0.0 2e-34 118.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGG42087.1 - 4.2e-24 84.6 0.2 7.7e-23 80.5 0.1 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Peptidase_C34 PF05413.11 EGG42087.1 - 0.077 13.3 0.0 13 6.1 0.0 2.8 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase RNA_pol_Rpb2_6 PF00562.28 EGG42088.1 - 5.1e-125 417.6 0.0 7.6e-125 417.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGG42088.1 - 2.6e-48 164.2 0.0 4e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGG42088.1 - 3.5e-32 110.7 0.1 7.5e-32 109.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGG42088.1 - 1.2e-27 95.8 0.1 2.9e-27 94.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGG42088.1 - 1.5e-23 83.5 0.0 3.4e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGG42088.1 - 4.9e-19 68.4 0.1 1.1e-18 67.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGG42088.1 - 7.5e-09 36.0 0.0 1.9e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FYVE_2 PF02318.16 EGG42088.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 EGG42088.1 - 0.27 11.2 2.3 0.59 10.1 1.5 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L37e PF01907.19 EGG42088.1 - 0.37 11.0 0.9 0.83 9.9 0.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e RecR PF02132.15 EGG42088.1 - 0.56 9.8 2.1 1.9 8.1 0.6 2.3 2 0 0 2 2 2 0 RecR protein RNA_pol_Rpb5_C PF01191.19 EGG42089.1 - 6.7e-27 93.2 0.1 7.9e-27 92.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain MG2 PF01835.19 EGG42090.1 - 0.0024 18.3 0.1 0.0051 17.2 0.1 1.6 1 0 0 1 1 1 1 MG2 domain CBM60 PF16841.5 EGG42090.1 - 0.064 13.7 0.2 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding MG2 PF01835.19 EGG42091.1 - 5.9e-05 23.4 0.2 0.01 16.2 0.1 2.5 2 1 0 2 2 2 2 MG2 domain P_proprotein PF01483.20 EGG42091.1 - 0.0072 16.3 0.0 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 Proprotein convertase P-domain Trp_ring PF18669.1 EGG42091.1 - 0.42 10.8 2.7 3.9 7.7 0.3 2.8 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain MG2 PF01835.19 EGG42092.1 - 0.0064 16.9 0.1 0.013 15.9 0.1 1.5 1 0 0 1 1 1 1 MG2 domain Big_3_5 PF16640.5 EGG42093.1 - 0.0095 16.1 2.1 0.024 14.8 1.1 2.2 2 1 0 2 2 2 1 Bacterial Ig-like domain (group 3) Aminotran_5 PF00266.19 EGG42094.1 - 3.3e-82 276.4 0.0 3.9e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGG42094.1 - 3.6e-07 29.7 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGG42094.1 - 7.9e-07 28.6 0.0 2.3e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGG42094.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGG42094.1 - 0.0021 16.6 0.0 0.0031 16.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 EGG42094.1 - 0.028 13.1 0.0 0.065 11.9 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain QueC PF06508.13 EGG42095.1 - 1.5e-09 37.6 0.4 4.1e-08 33.0 0.2 2.6 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGG42095.1 - 3.9e-08 32.5 0.2 2.5e-06 26.5 0.2 2.2 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 EGG42095.1 - 7.1e-08 31.9 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 EGG42095.1 - 7.4e-08 32.4 0.2 5.3e-07 29.6 0.2 2.1 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 EGG42095.1 - 4.5e-07 29.8 0.0 9.4e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase ThiI PF02568.14 EGG42095.1 - 5.2e-05 22.9 0.1 0.00012 21.7 0.1 1.6 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 EGG42095.1 - 0.049 12.9 0.9 0.06 12.6 0.4 1.6 2 1 0 2 2 2 0 Arginosuccinate synthase DUF111 PF01969.17 EGG42096.1 - 5.6e-93 312.0 0.2 6.8e-93 311.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 Ldh_1_N PF00056.23 EGG42097.1 - 4.1e-36 124.2 0.5 8.4e-36 123.2 0.5 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGG42097.1 - 9.6e-28 97.2 0.1 1.7e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AIRC PF00731.20 EGG42098.1 - 4.2e-15 55.6 4.4 7.5e-15 54.8 4.4 1.4 1 0 0 1 1 1 1 AIR carboxylase NAD_kinase PF01513.21 EGG42098.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase PrpR_N PF06506.11 EGG42098.1 - 0.013 15.1 1.6 0.15 11.6 0.2 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Radical_SAM PF04055.21 EGG42099.1 - 1.6e-13 51.4 0.0 3.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 EGG42099.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain TerY_C PF15616.6 EGG42100.1 - 0.019 15.1 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain Phage_integrase PF00589.22 EGG42101.1 - 7.2e-07 29.1 2.3 8.1e-06 25.7 0.7 2.8 2 1 0 2 2 2 1 Phage integrase family Alpha_adaptinC2 PF02883.20 EGG42101.1 - 0.051 13.9 1.2 0.1 12.9 1.2 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain DUF1664 PF07889.12 EGG42101.1 - 1.6 8.8 6.3 1.7 8.7 4.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Lactonase PF10282.9 EGG42102.1 - 0.0013 18.1 0.3 0.064 12.5 0.1 2.8 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 EGG42102.1 - 0.0028 16.2 1.0 0.27 9.7 0.1 2.7 2 1 0 3 3 3 2 Cytochrome D1 heme domain Arylesterase PF01731.20 EGG42102.1 - 0.0096 16.1 0.9 0.83 9.9 0.0 3.2 3 0 0 3 3 3 1 Arylesterase ANAPC4_WD40 PF12894.7 EGG42102.1 - 0.014 15.6 1.0 6.5 7.1 0.0 3.6 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4108 PF13390.6 EGG42102.1 - 0.045 13.7 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) Usp PF00582.26 EGG42103.1 - 1.8e-27 96.6 0.2 2.1e-27 96.3 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family Urb2 PF10441.9 EGG42103.1 - 0.0046 16.9 0.1 0.0057 16.6 0.1 1.1 1 0 0 1 1 1 1 Urb2/Npa2 family LuxC PF05893.14 EGG42103.1 - 0.017 14.2 0.3 0.02 13.9 0.3 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) HIT PF01230.23 EGG42103.1 - 0.15 12.8 0.6 0.48 11.2 0.3 1.8 1 1 1 2 2 2 0 HIT domain BEX PF04538.12 EGG42103.1 - 0.46 11.1 6.6 0.25 11.9 4.6 1.5 1 1 0 1 1 1 0 Brain expressed X-linked like family MinE PF03776.14 EGG42103.1 - 0.52 10.4 5.3 0.32 11.0 3.1 1.8 1 1 1 2 2 2 0 Septum formation topological specificity factor MinE ABC_tran PF00005.27 EGG42106.1 - 1.8e-31 109.5 0.0 2.2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG42106.1 - 1.3e-06 28.5 0.0 0.0025 17.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG42106.1 - 0.00077 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EGG42106.1 - 0.001 19.5 0.1 0.0099 16.3 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG42106.1 - 0.004 17.1 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EGG42106.1 - 0.004 16.9 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG42106.1 - 0.013 15.8 0.0 0.022 15.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGG42106.1 - 0.015 15.6 0.1 0.035 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGG42106.1 - 0.018 15.2 0.0 0.023 14.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EGG42106.1 - 0.022 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EGG42106.1 - 0.024 15.1 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGG42106.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EGG42106.1 - 0.029 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG42106.1 - 0.03 14.7 0.1 0.13 12.7 0.0 2.0 2 1 1 3 3 3 0 RNA helicase SMC_N PF02463.19 EGG42106.1 - 0.033 13.6 0.2 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EGG42106.1 - 0.036 14.2 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG42106.1 - 0.04 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 EGG42106.1 - 0.045 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EGG42106.1 - 0.099 13.2 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGG42106.1 - 0.12 12.2 0.1 0.23 11.4 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EGG42106.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG42106.1 - 0.17 12.1 0.2 0.25 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain NMT1_2 PF13379.6 EGG42107.1 - 1.1e-22 80.9 0.0 1.5e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 EGG42107.1 - 1.7e-18 67.4 0.0 2.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EGG42107.1 - 3.1e-07 30.2 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EGG42107.1 - 0.00038 20.0 0.0 0.0022 17.5 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 EGG42107.1 - 0.0081 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family Arginosuc_synth PF00764.19 EGG42108.1 - 1.8e-158 527.9 0.2 2.1e-158 527.7 0.2 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 EGG42108.1 - 6.6e-05 22.7 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 EGG42108.1 - 6.8e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGG42108.1 - 0.06 12.1 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase zinc_ribbon_4 PF13717.6 EGG42109.1 - 0.0002 21.2 0.6 0.14 12.1 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.6 EGG42109.1 - 0.0017 18.0 0.6 0.11 12.3 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EGG42109.1 - 0.003 17.4 0.2 0.0046 16.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 EGG42109.1 - 0.0034 16.9 0.7 0.0052 16.3 0.5 1.4 2 0 0 2 2 2 1 TFIIB zinc-binding zf_UBZ PF18439.1 EGG42109.1 - 0.038 13.6 1.6 2.8 7.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 EGG42109.1 - 0.047 13.7 0.5 0.073 13.1 0.5 1.3 1 1 0 1 1 1 0 zinc-ribbons DNA_RNApol_7kD PF03604.13 EGG42109.1 - 0.066 12.9 4.0 1 9.1 0.4 2.5 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 EGG42109.1 - 0.068 13.2 0.6 0.076 13.0 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EGG42109.1 - 0.079 13.1 2.7 0.8 9.9 0.1 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-HYPF PF07503.12 EGG42109.1 - 0.12 12.2 1.4 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 HypF finger Lar_restr_allev PF14354.6 EGG42109.1 - 0.13 12.7 1.4 0.47 10.9 1.4 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar SR1P PF13790.6 EGG42109.1 - 0.18 12.0 2.4 1.9 8.7 0.1 2.1 1 1 1 2 2 2 0 SR1 protein RimK PF08443.11 EGG42110.1 - 6.9e-31 107.3 0.0 9.6e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EGG42110.1 - 2.5e-11 43.3 0.0 3.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 EGG42110.1 - 3.7e-09 36.2 0.0 3.4e-05 23.2 0.0 2.7 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EGG42110.1 - 5.3e-08 33.1 0.1 3.4e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 EGG42110.1 - 2.4e-07 30.3 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp PF02222.22 EGG42110.1 - 8.7e-07 28.7 0.0 1.2e-05 25.0 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EGG42110.1 - 0.0002 21.2 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 EGG42110.1 - 0.00038 20.0 0.0 0.0019 17.8 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EGG42110.1 - 0.0012 18.4 0.0 0.2 11.2 0.0 2.5 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 EGG42110.1 - 0.028 14.0 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain MlrC_C PF07171.12 EGG42110.1 - 0.065 13.4 0.0 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 MlrC C-terminus ATP-grasp_2 PF08442.10 EGG42110.1 - 0.079 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 EGG42110.1 - 0.081 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Semialdhyde_dh PF01118.24 EGG42111.1 - 2e-35 121.9 0.0 3.2e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 EGG42111.1 - 4.7e-19 69.2 0.0 7.9e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Sacchrp_dh_NADP PF03435.18 EGG42111.1 - 9.6e-05 22.7 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 EGG42111.1 - 0.00049 20.9 0.0 0.00096 20.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 EGG42111.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 EGG42111.1 - 0.1 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NUDIX PF00293.28 EGG42112.1 - 3.2e-11 43.4 0.0 3.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MTHFR PF02219.17 EGG42113.1 - 2.4e-08 33.7 0.0 0.00046 19.6 0.0 2.1 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase Beta_protein PF14350.6 EGG42113.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Beta protein Pterin_bind PF00809.22 EGG42114.1 - 3.4e-30 105.5 0.0 4.7e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme Met_synt_B12 PF02965.17 EGG42114.1 - 3.7e-25 88.9 0.1 1.9e-24 86.6 0.1 2.0 1 1 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding PF02310.19 EGG42114.1 - 1.1e-18 67.5 0.0 2.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 EGG42114.1 - 1.9e-18 66.6 0.0 4.9e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.16 EGG42114.1 - 0.00017 20.4 0.0 0.00032 19.5 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit adh_short PF00106.25 EGG42114.1 - 0.0087 15.5 0.4 0.041 13.3 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase S-methyl_trans PF02574.16 EGG42115.1 - 7.2e-59 199.8 0.0 8.1e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase 2-Hacid_dh_C PF02826.19 EGG42116.1 - 1.3e-63 213.6 0.4 2.2e-63 212.8 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG42116.1 - 1.2e-29 102.7 0.2 1.3e-29 102.6 0.2 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGG42116.1 - 0.0031 17.7 0.7 0.01 16.0 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase LXG PF04740.12 EGG42116.1 - 0.024 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Cu-oxidase_3 PF07732.15 EGG42117.1 - 9.4e-11 41.8 2.0 2.7e-09 37.1 0.4 2.5 2 0 0 2 2 2 2 Multicopper oxidase DUF4420 PF14390.6 EGG42117.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) Lyase_1 PF00206.20 EGG42118.1 - 2.2e-86 290.1 1.4 2.7e-86 289.8 1.4 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGG42118.1 - 1.2e-13 51.2 0.0 3.3e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Radical_SAM PF04055.21 EGG42119.1 - 4.9e-20 72.6 0.1 7.1e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EGG42119.1 - 2e-15 56.6 0.1 2e-15 56.6 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TRAM_2 PF18693.1 EGG42119.1 - 0.0094 16.1 0.2 0.05 13.8 0.2 2.3 1 1 0 1 1 1 1 TRAM domain zf-PARP PF00645.18 EGG42119.1 - 0.034 15.0 0.3 0.12 13.2 0.3 2.0 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region TRAM PF01938.20 EGG42119.1 - 0.053 13.5 0.1 0.2 11.6 0.1 2.1 1 0 0 1 1 1 0 TRAM domain Tubulin PF00091.25 EGG42120.1 - 9.3e-16 58.6 3.0 2.1e-14 54.2 0.1 2.6 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain PS_Dcarbxylase PF02666.15 EGG42120.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase Tubulin_2 PF13809.6 EGG42120.1 - 0.087 12.0 0.3 2.5 7.2 0.0 2.2 1 1 0 2 2 2 0 Tubulin like Redoxin PF08534.10 EGG42121.1 - 8.8e-07 28.7 0.1 0.00024 20.9 0.0 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EGG42121.1 - 2.4e-06 27.5 0.1 3.4e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGG42121.1 - 0.0048 17.2 0.1 4.2 7.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_4 PF13462.6 EGG42121.1 - 0.0091 16.2 0.0 0.079 13.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGG42121.1 - 0.019 15.4 0.3 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain GSHPx PF00255.19 EGG42121.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase AbiJ_NTD5 PF18865.1 EGG42121.1 - 0.15 11.9 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Neur_chan_memb PF02932.16 EGG42122.1 - 1.8e-05 24.9 3.1 3.6e-05 23.9 2.7 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region SNase PF00565.17 EGG42123.1 - 2.4e-07 31.2 0.0 3.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pput2613-deam PF14427.6 EGG42123.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 Pput_2613-like deaminase Copper-bind PF00127.20 EGG42124.1 - 1.3e-10 41.6 0.5 1.3e-10 41.6 0.5 1.6 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EGG42124.1 - 9.5e-07 28.9 1.3 0.00016 21.7 1.3 2.4 1 1 0 1 1 1 1 Cupredoxin-like domain SoxE PF06525.11 EGG42124.1 - 1.9e-05 24.2 0.5 3.2e-05 23.4 0.2 1.7 2 1 0 2 2 2 1 Sulfocyanin (SoxE) domain Protocadherin PF08374.11 EGG42124.1 - 0.065 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Protocadherin DUF308 PF03729.13 EGG42125.1 - 0.013 15.8 7.0 0.016 15.6 7.0 1.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) DUF202 PF02656.15 EGG42125.1 - 3.4 8.2 5.7 11 6.6 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Stealth_CR4 PF17103.5 EGG42126.1 - 0.069 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 DUF1410 PF07198.11 EGG42127.1 - 0.034 14.7 1.5 0.061 13.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) Glyco_hydro_5_C PF18564.1 EGG42127.1 - 0.072 13.6 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain Ribosomal_L15e PF00827.17 EGG42128.1 - 1.2e-44 152.3 4.9 1.5e-44 152.0 4.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Phage_integrase PF00589.22 EGG42129.1 - 7.4e-13 48.6 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 EGG42129.1 - 0.046 14.2 1.4 0.3 11.6 1.4 2.4 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ribosomal_S20p PF01649.18 EGG42129.1 - 2.5 8.8 9.1 2.6 8.7 0.5 3.8 4 0 0 4 4 4 0 Ribosomal protein S20 hEGF PF12661.7 EGG42130.1 - 0.077 13.7 3.1 0.26 12.0 3.1 1.9 1 1 0 1 1 1 0 Human growth factor-like EGF RHH_1 PF01402.21 EGG42131.1 - 9.1e-05 22.3 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family CLIP1_ZNF PF16641.5 EGG42131.1 - 0.026 14.4 2.0 0.026 14.4 2.0 1.5 2 0 0 2 2 2 0 CLIP1 zinc knuckle RGCC PF15151.6 EGG42131.1 - 0.028 14.7 0.0 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family VirD1 PF07328.11 EGG42131.1 - 0.032 14.2 0.0 0.032 14.2 0.0 1.0 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 HTH_52 PF18576.1 EGG42132.1 - 0.056 13.7 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Astacin PF01400.24 EGG42133.1 - 0.0011 18.6 0.2 0.0096 15.6 0.0 2.5 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 EGG42133.1 - 0.0082 16.7 1.4 0.0082 16.7 1.4 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Binary_toxB PF03495.14 EGG42133.1 - 0.22 11.8 0.9 0.74 10.0 0.9 1.9 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Reprolysin_5 PF13688.6 EGG42133.1 - 0.54 10.4 7.5 0.079 13.1 2.3 2.2 2 1 1 3 3 3 0 Metallo-peptidase family M12 Metallopep PF12044.8 EGG42133.1 - 0.88 8.1 4.6 0.97 8.0 2.1 1.9 2 0 0 2 2 2 0 Putative peptidase family EF-hand_8 PF13833.6 EGG42133.1 - 4.2 7.3 7.2 6.1 6.8 0.4 3.4 2 1 1 3 3 3 0 EF-hand domain pair Aldedh PF00171.22 EGG42135.1 - 6.1e-101 338.2 0.2 6.9e-101 338.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_10 PF05971.12 EGG42135.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Pro_dh PF01619.18 EGG42136.1 - 2.4e-26 92.9 0.0 3.8e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Telomere_reg-2 PF10193.9 EGG42136.1 - 0.079 13.4 0.0 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 Telomere length regulation protein Peptidase_M15_2 PF05951.13 EGG42136.1 - 0.082 12.6 0.2 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) HicB_lk_antitox PF15919.5 EGG42136.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system NadA PF02445.16 EGG42137.1 - 2.8e-113 378.0 2.4 3.1e-113 377.9 2.4 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein DUF108 PF01958.18 EGG42138.1 - 3.2e-32 110.7 2.9 7e-32 109.7 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 EGG42138.1 - 4.4e-15 56.4 0.0 7.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EGG42138.1 - 0.039 14.4 0.0 0.081 13.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGG42138.1 - 0.064 12.6 0.0 0.62 9.4 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGG42138.1 - 0.072 13.9 0.1 0.47 11.3 0.0 2.2 2 1 1 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold NurA PF09376.10 EGG42141.1 - 8.5e-18 64.9 0.1 1.2e-17 64.5 0.1 1.2 1 0 0 1 1 1 1 NurA domain DUF2608 PF11019.8 EGG42141.1 - 0.074 12.5 0.8 0.12 11.9 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) OpuAC PF04069.12 EGG42141.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.3 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system DUF87 PF01935.17 EGG42142.1 - 4.1e-37 128.5 3.1 4.1e-37 128.5 3.1 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain DUF853 PF05872.12 EGG42142.1 - 0.00015 20.5 0.1 0.01 14.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) HAS-barrel PF09378.10 EGG42142.1 - 0.00045 20.3 0.2 0.0013 18.9 0.2 1.9 1 0 0 1 1 1 1 HAS barrel domain TrwB_AAD_bind PF10412.9 EGG42142.1 - 0.024 13.6 0.2 0.07 12.0 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 EGG42142.1 - 0.028 14.9 0.0 0.062 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF4709 PF15821.5 EGG42142.1 - 0.057 13.7 1.0 0.15 12.3 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) AAA_16 PF13191.6 EGG42142.1 - 0.09 13.2 0.0 0.3 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Metallophos_2 PF12850.7 EGG42143.1 - 2.8e-08 34.1 0.2 4.4e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGG42143.1 - 8.4e-08 32.9 3.0 1.3e-07 32.3 3.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CENP-C_C PF11699.8 EGG42143.1 - 0.0084 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like RST PF12174.8 EGG42143.1 - 0.076 13.0 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DUF211 PF02680.14 EGG42143.1 - 0.3 11.3 3.9 9.3 6.5 0.2 3.5 3 1 1 4 4 4 0 Uncharacterized ArCR, COG1888 SMC_N PF02463.19 EGG42144.1 - 2.6e-17 63.0 22.2 4.8e-10 39.3 1.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGG42144.1 - 3.2e-16 60.4 33.1 3.2e-16 60.4 33.1 4.1 1 1 2 3 3 1 1 AAA domain AAA_21 PF13304.6 EGG42144.1 - 2.8e-12 47.1 9.5 2.3e-06 27.6 0.4 3.2 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG42144.1 - 1.6e-11 44.6 53.0 5e-07 29.8 24.9 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGG42144.1 - 8.6e-09 35.0 0.1 1.7e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EGG42144.1 - 2.4e-06 27.3 1.2 2.4e-06 27.3 1.2 2.8 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGG42144.1 - 1.1e-05 25.6 0.1 2.2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EGG42144.1 - 0.00064 20.3 24.8 0.014 15.9 0.1 5.1 2 1 1 3 3 2 2 ABC transporter RsgA_GTPase PF03193.16 EGG42144.1 - 0.01 15.7 0.1 0.01 15.7 0.1 3.8 5 1 1 6 6 6 0 RsgA GTPase DNA_ligase_ZBD PF03119.16 EGG42144.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain MukB PF04310.12 EGG42144.1 - 0.24 11.2 0.0 0.24 11.2 0.0 3.3 3 2 1 5 5 5 0 MukB N-terminal MMR_HSR1 PF01926.23 EGG42144.1 - 0.69 10.0 6.3 0.74 9.9 0.1 3.6 2 1 1 3 3 3 0 50S ribosome-binding GTPase CxxCxxCC PF03692.15 EGG42148.1 - 3.3e-09 37.3 0.6 6.1e-09 36.4 0.6 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Copper-bind PF00127.20 EGG42149.1 - 4.4e-18 65.5 2.2 1.8e-09 37.9 0.2 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EGG42149.1 - 2.6e-14 53.2 0.0 8.2e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 Cupredoxin-like domain SprT-like PF10263.9 EGG42150.1 - 0.0015 18.4 0.2 0.0024 17.7 0.2 1.4 1 1 0 1 1 1 1 SprT-like family DUF45 PF01863.17 EGG42150.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 Peptidase_M76 PF09768.9 EGG42150.1 - 0.035 13.9 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family Cu-oxidase_3 PF07732.15 EGG42151.1 - 9.3e-28 96.6 5.5 5.3e-25 87.7 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG42151.1 - 9.2e-15 54.6 8.5 4e-05 23.4 0.0 3.7 4 0 0 4 4 4 3 Multicopper oxidase Cupredoxin_1 PF13473.6 EGG42151.1 - 3.7e-09 36.6 0.1 0.00015 21.8 0.0 3.6 3 0 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.20 EGG42151.1 - 7.3e-09 36.0 8.6 5.8e-06 26.7 0.4 4.0 3 2 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family DUF359 PF04019.12 EGG42152.1 - 7e-34 116.2 0.0 1.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF359) ParA PF10609.9 EGG42153.1 - 5.1e-100 334.0 0.2 6.7e-100 333.6 0.2 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 EGG42153.1 - 6.2e-18 64.8 0.7 1.9e-17 63.2 0.1 2.2 3 0 0 3 3 3 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 EGG42153.1 - 1.2e-13 51.3 0.0 4.8e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGG42153.1 - 1e-09 38.6 1.5 9.2e-08 32.2 0.8 2.4 1 1 1 2 2 2 1 AAA domain MipZ PF09140.11 EGG42153.1 - 7.9e-08 31.9 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 EGG42153.1 - 7.5e-07 29.2 1.0 0.006 16.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.18 EGG42153.1 - 1e-06 28.4 0.2 0.00047 19.7 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EGG42153.1 - 2e-05 23.9 2.5 3.1e-05 23.3 0.7 2.0 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 EGG42153.1 - 0.0025 17.1 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 EGG42153.1 - 0.0033 17.2 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CBP_BcsQ PF06564.12 EGG42153.1 - 0.0039 16.7 0.1 0.017 14.6 0.1 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EGG42153.1 - 0.018 14.0 0.4 0.028 13.4 0.4 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EGG42153.1 - 0.025 14.1 0.7 0.053 13.1 0.7 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EGG42153.1 - 0.084 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase S1 PF00575.23 EGG42154.1 - 2.8e-14 53.2 0.0 4.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 EGG42154.1 - 5.3e-06 26.7 0.0 1.5e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1_2 PF13509.6 EGG42154.1 - 0.0078 16.2 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 S1 domain BPL_C PF02237.17 EGG42154.1 - 0.022 14.7 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Spt4 PF06093.13 EGG42155.1 - 1.5e-13 50.6 0.5 1.9e-13 50.3 0.5 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.15 EGG42155.1 - 0.003 17.1 0.8 0.0039 16.7 0.8 1.2 1 0 0 1 1 1 1 RecR protein zf-ribbon_3 PF13248.6 EGG42155.1 - 0.054 12.9 1.5 1.2 8.7 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain QRPTase_C PF01729.19 EGG42156.1 - 3.3e-55 186.4 1.2 4.5e-55 186.0 1.2 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGG42156.1 - 2e-28 98.2 0.1 5.2e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ufm1 PF03671.14 EGG42156.1 - 0.0004 20.4 0.2 0.0014 18.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin fold modifier 1 protein Ribul_P_3_epim PF00834.19 EGG42156.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ANAPC3 PF12895.7 EGG42157.1 - 4.4e-14 52.5 0.8 4.8e-08 33.1 0.0 1.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGG42157.1 - 7e-13 47.8 1.3 4.9e-05 23.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42157.1 - 1.7e-11 43.3 0.0 0.00036 20.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG42157.1 - 4.2e-10 39.0 1.1 0.00012 22.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42157.1 - 5.3e-10 39.7 0.0 1.2e-07 32.1 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG42157.1 - 2.7e-06 27.6 0.0 0.0034 17.6 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG42157.1 - 2e-05 24.3 0.1 0.018 15.1 0.0 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG42157.1 - 3.7e-05 24.3 0.0 5.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG42157.1 - 0.00029 21.3 0.0 0.18 12.5 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG42157.1 - 0.00048 20.3 0.2 0.19 12.2 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42157.1 - 0.0007 19.6 0.7 0.97 9.5 0.0 3.1 1 1 2 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat DUF4919 PF16266.5 EGG42157.1 - 0.0019 18.2 0.9 0.03 14.3 0.4 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4919) TPR_14 PF13428.6 EGG42157.1 - 0.0056 17.4 0.0 4 8.5 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGG42157.1 - 0.026 14.5 0.5 0.071 13.1 0.3 1.8 1 1 0 1 1 1 0 Putative TPR-like repeat DXP_reductoisom PF02670.16 EGG42157.1 - 0.026 15.2 0.0 0.049 14.3 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TPR_3 PF07720.12 EGG42157.1 - 0.031 14.3 4.1 0.084 12.9 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4284 PF14112.6 EGG42157.1 - 0.046 14.6 0.9 0.14 13.1 0.2 1.8 1 1 1 2 2 2 0 Immunity protein 22 ChAPs PF09295.10 EGG42157.1 - 0.051 12.6 0.1 0.059 12.4 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) FIVAR PF07554.13 EGG42157.1 - 0.34 11.7 3.8 0.97 10.2 0.3 2.8 3 0 0 3 3 3 0 FIVAR domain Arginase PF00491.21 EGG42158.1 - 2.5e-59 201.1 0.0 3e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family Urocanase_C PF17392.2 EGG42158.1 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Urocanase C-terminal domain UPF0489 PF12640.7 EGG42158.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain UvrA_inter PF17760.1 EGG42159.1 - 4e-35 120.2 1.5 6.8e-35 119.4 0.7 1.8 2 0 0 2 2 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 EGG42159.1 - 9.8e-35 119.2 0.1 2.2e-31 108.4 0.0 4.4 5 0 0 5 5 4 1 UvrA DNA-binding domain ABC_tran PF00005.27 EGG42159.1 - 4.7e-23 82.2 0.1 1.5e-09 38.5 0.0 4.4 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 EGG42159.1 - 1.4e-10 41.0 0.9 0.058 12.8 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG42159.1 - 2.9e-08 34.3 0.1 0.024 15.0 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGG42159.1 - 1.3e-07 31.7 0.5 0.0016 18.3 0.2 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGG42159.1 - 2.8e-07 30.2 0.4 0.027 14.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGG42159.1 - 7.4e-07 29.3 5.5 0.14 11.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 EGG42159.1 - 3.7e-05 23.0 0.1 0.062 12.5 0.0 3.3 4 0 0 4 4 4 1 NB-ARC domain AAA_14 PF13173.6 EGG42159.1 - 3.9e-05 23.7 0.0 0.61 10.1 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 EGG42159.1 - 6.6e-05 23.2 0.9 0.56 10.5 0.0 4.0 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 EGG42159.1 - 8.3e-05 22.8 0.3 0.26 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EGG42159.1 - 0.00011 22.0 9.2 0.055 13.2 0.0 4.5 3 2 0 5 5 5 1 AAA ATPase domain AAA_25 PF13481.6 EGG42159.1 - 0.00021 20.9 0.2 0.24 10.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 EGG42159.1 - 0.00028 21.5 5.5 0.0068 16.9 0.1 3.4 3 0 0 3 3 3 1 AAA domain DnaJ_CXXCXGXG PF00684.19 EGG42159.1 - 0.00035 20.9 8.5 0.022 15.1 0.4 4.0 3 1 0 3 3 3 1 DnaJ central domain Viral_helicase1 PF01443.18 EGG42159.1 - 0.00037 20.3 0.0 0.049 13.4 0.1 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EGG42159.1 - 0.00046 20.2 1.1 0.37 10.7 0.0 3.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EGG42159.1 - 0.00046 20.7 0.2 1.7 9.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain APS_kinase PF01583.20 EGG42159.1 - 0.00053 19.9 0.3 1.5 8.7 0.0 2.8 3 0 0 3 3 2 2 Adenylylsulphate kinase MMR_HSR1 PF01926.23 EGG42159.1 - 0.00096 19.2 0.2 0.11 12.6 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase cobW PF02492.19 EGG42159.1 - 0.0013 18.3 0.7 0.36 10.4 0.1 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 EGG42159.1 - 0.0014 18.1 0.0 1.3 8.3 0.0 2.8 2 0 0 2 2 2 1 KaiC NACHT PF05729.12 EGG42159.1 - 0.0019 18.1 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 EGG42159.1 - 0.0036 16.8 0.4 0.6 9.6 0.0 3.3 4 0 0 4 4 4 1 P-loop containing dynein motor region T2SSE PF00437.20 EGG42159.1 - 0.0074 15.4 0.2 3 6.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.9 EGG42159.1 - 0.0094 15.2 0.0 3.8 6.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EGG42159.1 - 0.013 15.9 0.1 5.5 7.4 0.0 3.2 3 0 0 3 3 2 0 RNA helicase NTPase_1 PF03266.15 EGG42159.1 - 0.016 15.1 0.9 2.1 8.2 0.0 3.6 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 EGG42159.1 - 0.02 14.2 0.0 3 7.1 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin MeaB PF03308.16 EGG42159.1 - 0.028 13.4 0.0 0.69 8.8 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RACo_linker PF17650.1 EGG42159.1 - 0.039 13.8 0.1 9.2 6.2 0.0 3.1 4 0 0 4 4 2 0 RACo linker region AAA_24 PF13479.6 EGG42159.1 - 0.067 12.9 3.6 28 4.4 0.0 3.7 4 0 0 4 4 3 0 AAA domain MobB PF03205.14 EGG42159.1 - 0.073 13.0 0.0 6 6.8 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2972 PF11186.8 EGG42159.1 - 0.084 12.8 0.1 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) AAA_28 PF13521.6 EGG42159.1 - 0.087 13.1 0.1 23 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGG42159.1 - 0.089 12.5 0.0 19 4.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain dNK PF01712.19 EGG42159.1 - 0.1 12.5 0.1 5.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Deoxynucleoside kinase PRK PF00485.18 EGG42159.1 - 0.11 12.2 0.4 3 7.5 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family zf-ribbon_3 PF13248.6 EGG42159.1 - 0.36 10.3 2.1 0.64 9.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain UvrB_inter PF17757.1 EGG42160.1 - 1.8e-28 98.5 1.4 7.3e-28 96.6 0.6 2.4 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 EGG42160.1 - 1.1e-22 79.6 4.7 2.9e-22 78.2 4.7 1.8 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 EGG42160.1 - 5.1e-19 68.7 1.3 1.3e-18 67.3 0.2 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UVR PF02151.19 EGG42160.1 - 1.8e-10 40.2 4.5 1.1e-09 37.8 4.5 2.5 1 0 0 1 1 1 1 UvrB/uvrC motif ResIII PF04851.15 EGG42160.1 - 5.9e-08 32.9 3.3 1.6e-07 31.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG42160.1 - 5.2e-07 29.6 0.2 0.00029 20.7 0.1 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGG42160.1 - 0.0012 18.6 0.0 0.037 13.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain Rhomboid_N PF12122.8 EGG42160.1 - 0.021 15.0 0.1 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease Met_synt_B12 PF02965.17 EGG42160.1 - 0.054 12.9 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain AAA_22 PF13401.6 EGG42160.1 - 0.062 13.6 0.8 0.95 9.7 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGG42160.1 - 0.23 11.8 4.5 7.2 6.9 0.2 2.9 3 1 0 3 3 2 0 AAA domain ABC_tran PF00005.27 EGG42160.1 - 0.26 11.8 2.0 5.1 7.6 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Tup_N PF08581.10 EGG42160.1 - 2.9 8.3 13.1 4.9 7.5 0.0 4.0 3 1 0 3 3 3 0 Tup N-terminal Pyridox_ox_2 PF12900.7 EGG42161.1 - 1.2e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EGG42161.1 - 0.13 12.5 0.0 0.42 10.8 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase eIF3_subunit PF08597.10 EGG42162.1 - 0.026 14.4 10.7 0.027 14.4 10.7 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cep57_MT_bd PF06657.13 EGG42162.1 - 0.027 14.9 4.0 0.033 14.7 4.0 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Tht1 PF04163.12 EGG42162.1 - 0.032 13.0 2.4 0.036 12.8 2.4 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Glyco_hydro_26 PF02156.15 EGG42162.1 - 0.057 12.9 0.1 0.059 12.8 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 ELK PF03789.13 EGG42162.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.1 4 0 0 4 4 4 0 ELK domain LOH1CR12 PF10158.9 EGG42164.1 - 0.068 13.2 3.1 0.075 13.1 2.1 1.5 1 1 1 2 2 2 0 Tumour suppressor protein Bac_luciferase PF00296.20 EGG42165.1 - 2.9e-53 181.3 0.0 3.9e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe-ADH PF00465.19 EGG42166.1 - 2.4e-48 164.8 0.0 5.5e-48 163.6 0.0 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGG42166.1 - 6.8e-17 62.0 0.0 9.4e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EGG42166.1 - 0.0027 16.9 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 3-dehydroquinate synthase DUF4147 PF13660.6 EGG42167.1 - 6.2e-67 225.5 0.0 8.4e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 EGG42167.1 - 2.5e-29 101.6 0.1 4.4e-28 97.6 0.1 2.3 2 0 0 2 2 2 1 MOFRL family Usp PF00582.26 EGG42168.1 - 3.2e-30 105.5 0.0 3.5e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family FlxA PF14282.6 EGG42169.1 - 0.029 14.4 0.3 0.47 10.5 0.1 2.0 2 0 0 2 2 2 0 FlxA-like protein AA_permease_2 PF13520.6 EGG42170.1 - 1.9e-52 178.6 56.0 2.3e-52 178.3 56.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG42170.1 - 1.9e-34 119.1 49.6 2.4e-34 118.8 49.6 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 EGG42170.1 - 0.029 13.2 38.8 0.021 13.6 26.4 2.4 2 1 0 2 2 2 0 Spore germination protein E1-E2_ATPase PF00122.20 EGG42171.1 - 9.8e-48 162.1 0.8 9.8e-48 162.1 0.8 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGG42171.1 - 1.3e-36 126.9 0.3 2.2e-36 126.1 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG42171.1 - 0.0002 21.8 0.0 0.00053 20.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG42171.1 - 0.00042 20.1 1.1 0.015 15.1 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1402 PF07182.11 EGG42171.1 - 0.1 11.7 0.0 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1402) ABC_membrane PF00664.23 EGG42171.1 - 0.41 10.2 3.6 0.17 11.5 0.6 1.9 2 0 0 2 2 2 0 ABC transporter transmembrane region CBS PF00571.28 EGG42172.1 - 1.9e-48 162.7 14.8 5.2e-12 46.0 0.2 4.1 4 0 0 4 4 4 4 CBS domain Peptidase_S55 PF05580.12 EGG42172.1 - 0.0034 17.4 0.9 0.0051 16.8 0.4 1.7 1 1 0 1 1 1 1 SpoIVB peptidase S55 PduV-EutP PF10662.9 EGG42172.1 - 0.022 14.5 9.7 2.8 7.7 0.6 4.1 2 1 2 4 4 4 0 Ethanolamine utilisation - propanediol utilisation EMC1_C PF07774.13 EGG42172.1 - 0.032 13.9 1.9 0.087 12.5 1.1 1.9 1 1 1 2 2 2 0 ER membrane protein complex subunit 1, C-terminal SPAN PF02510.14 EGG42172.1 - 0.16 11.2 0.8 0.19 10.8 0.8 1.3 1 0 0 1 1 1 0 Surface presentation of antigens protein Radical_SAM PF04055.21 EGG42173.1 - 4.4e-10 40.2 2.2 4.6e-10 40.1 0.2 2.0 3 0 0 3 3 3 1 Radical SAM superfamily AdoMet_Synthase PF01941.19 EGG42174.1 - 3.2e-72 243.5 0.1 3.8e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) AdoMet_Synthase PF01941.19 EGG42175.1 - 2.6e-47 161.5 0.6 2.9e-47 161.3 0.6 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) PCMT PF01135.19 EGG42176.1 - 5e-60 202.9 0.0 6e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGG42176.1 - 3.7e-09 36.6 0.0 5.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EGG42176.1 - 1.5e-08 34.5 0.0 3.2e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 EGG42176.1 - 4.7e-08 32.4 0.0 6.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGG42176.1 - 9.6e-07 29.4 0.0 2.4e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG42176.1 - 6.5e-05 23.5 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EGG42176.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GidB PF02527.15 EGG42176.1 - 0.00023 20.5 0.1 0.00059 19.2 0.0 1.7 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G MTS PF05175.14 EGG42176.1 - 0.00046 19.8 0.0 0.00098 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGG42176.1 - 0.00056 19.4 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EGG42176.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.17 EGG42176.1 - 0.0077 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin Methyltransf_32 PF13679.6 EGG42176.1 - 0.0093 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG42176.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 EGG42176.1 - 0.027 13.6 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.9 EGG42176.1 - 0.032 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 EGG42176.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DOT1 PF08123.13 EGG42176.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 EGG42176.1 - 0.037 15.1 0.0 0.065 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGG42176.1 - 0.049 13.5 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Lambda_CIII PF02061.16 EGG42176.1 - 0.059 13.4 0.0 3 8.0 0.0 3.0 3 0 0 3 3 3 0 Lambda Phage CIII PrmA PF06325.13 EGG42176.1 - 0.076 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MgtC PF02308.16 EGG42177.1 - 1.2e-38 132.2 12.3 1.5e-38 131.9 12.3 1.0 1 0 0 1 1 1 1 MgtC family PhoR PF11808.8 EGG42177.1 - 1.3 9.4 0.1 1.3 9.4 0.1 2.2 2 1 0 2 2 2 0 Phosphate regulon sensor protein PhoR Cpn60_TCP1 PF00118.24 EGG42178.1 - 2.9e-172 573.7 20.7 3.3e-172 573.5 20.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.6 EGG42178.1 - 0.0079 16.1 0.0 0.04 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3924) Zn-ribbon_8 PF09723.10 EGG42179.1 - 0.00054 20.0 0.3 0.00068 19.7 0.3 1.2 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EGG42179.1 - 0.002 17.6 0.9 0.8 9.3 0.1 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding HypA PF01155.19 EGG42179.1 - 0.0047 16.9 0.1 0.0049 16.9 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rtf2 PF04641.12 EGG42179.1 - 0.0066 15.9 0.2 0.0066 15.9 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C2H2_4 PF13894.6 EGG42179.1 - 0.019 15.7 0.6 1.8 9.6 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TFIIB PF13453.6 EGG42179.1 - 0.027 13.8 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2072 PF09845.9 EGG42179.1 - 0.046 14.0 0.1 0.05 13.9 0.1 1.0 1 0 0 1 1 1 0 Zn-ribbon containing protein RecR PF02132.15 EGG42179.1 - 0.048 13.2 0.6 3.1 7.4 0.1 2.1 2 0 0 2 2 2 0 RecR protein UPF0547 PF10571.9 EGG42179.1 - 0.098 12.8 1.8 5.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ADK_lid PF05191.14 EGG42179.1 - 0.21 11.6 1.9 0.59 10.2 1.9 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid RNA_pol_A_CTD PF03118.15 EGG42180.1 - 0.055 13.2 2.0 0.42 10.4 1.3 2.2 1 1 1 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Usp PF00582.26 EGG42181.1 - 3.4e-15 56.8 0.0 3.8e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 EGG42182.1 - 2.3e-05 24.9 0.0 2.7e-05 24.7 0.0 1.2 1 1 0 1 1 1 1 Universal stress protein family Glycos_trans_3N PF02885.17 EGG42183.1 - 2e-09 37.2 0.0 3.2e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 EGG42183.1 - 5.7e-08 32.7 0.0 1.6e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Molydop_binding PF01568.21 EGG42183.1 - 0.00021 21.3 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain CDC48_N PF02359.18 EGG42183.1 - 0.00033 20.8 0.1 0.00071 19.7 0.1 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain DUF1905 PF08922.11 EGG42183.1 - 0.079 13.0 0.3 1 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) PYNP_C PF07831.13 EGG42184.1 - 3.2e-12 45.9 0.2 5.8e-12 45.1 0.2 1.4 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2254 PF10011.9 EGG42184.1 - 0.0063 15.4 0.1 0.0086 14.9 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) CAT_RBD PF03123.15 EGG42184.1 - 0.084 12.8 1.4 0.49 10.4 0.8 2.4 1 1 1 2 2 2 0 CAT RNA binding domain Pribosyltran_N PF13793.6 EGG42185.1 - 8.8e-25 86.9 0.0 1.4e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGG42185.1 - 1.7e-09 37.4 0.0 4.3e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG42185.1 - 0.00027 20.5 0.0 0.00058 19.4 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.6 EGG42185.1 - 0.00076 19.6 0.1 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain PRTase_2 PF15609.6 EGG42185.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase DUF4419 PF14388.6 EGG42185.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) AAA_33 PF13671.6 EGG42186.1 - 5e-12 46.2 1.3 1.8e-10 41.1 0.1 2.1 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 EGG42186.1 - 9.6e-05 22.0 2.0 0.00025 20.6 0.7 1.8 1 1 1 2 2 2 1 Chromatin associated protein KTI12 PLRV_ORF5 PF01690.17 EGG42186.1 - 0.037 12.8 0.0 0.046 12.4 0.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DPBB_1 PF03330.18 EGG42186.1 - 0.058 13.7 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 Lytic transglycolase FlpD PF02662.16 EGG42187.1 - 0.0068 16.4 1.0 0.011 15.7 0.4 1.5 1 1 1 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Syntaxin_2 PF14523.6 EGG42187.1 - 0.029 14.7 1.7 0.035 14.5 1.7 1.1 1 0 0 1 1 1 0 Syntaxin-like protein SNX17_FERM_C PF18116.1 EGG42187.1 - 0.076 13.1 1.2 0.086 12.9 1.2 1.0 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain Pox_TAA1 PF03295.14 EGG42187.1 - 0.13 12.2 2.1 1 9.3 0.2 2.1 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal LacI PF00356.21 EGG42187.1 - 0.28 11.0 1.6 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DNase-RNase PF02577.14 EGG42188.1 - 2.9e-11 43.1 0.0 3.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease CBS PF00571.28 EGG42189.1 - 1.7e-09 37.9 0.1 8.2e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 CBS domain Zip PF02535.22 EGG42191.1 - 2.6e-08 33.5 3.4 3.1e-08 33.2 3.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Mntp PF02659.15 EGG42191.1 - 0.1 12.4 3.3 0.11 12.3 1.5 1.9 1 1 1 2 2 2 0 Putative manganese efflux pump Response_reg PF00072.24 EGG42192.1 - 7.6e-06 26.1 0.0 8.3e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EGG42193.1 - 2.9e-12 46.7 0.0 3.3e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Tox-REase-9 PF15650.6 EGG42193.1 - 0.039 14.2 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 Response_reg PF00072.24 EGG42195.1 - 7e-25 87.4 0.1 8.2e-25 87.2 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EGG42196.1 - 1.7e-24 86.2 0.7 2.2e-24 85.8 0.7 1.2 1 0 0 1 1 1 1 Response regulator receiver domain DUF5475 PF17569.2 EGG42196.1 - 0.024 14.9 0.0 0.061 13.6 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5475) DUF2659 PF10858.8 EGG42196.1 - 0.056 13.1 0.1 0.064 12.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2659) AsnC_trans_reg PF01037.21 EGG42197.1 - 4.1e-08 33.1 0.0 4.9e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 EGG42197.1 - 0.062 13.4 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 NapD protein Ten1_2 PF15490.6 EGG42197.1 - 0.068 12.9 0.1 0.083 12.6 0.1 1.0 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DUF2129 PF09902.9 EGG42197.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) AsnC_trans_reg PF01037.21 EGG42198.1 - 3.5e-11 42.9 0.0 3.9e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain RimK PF08443.11 EGG42198.1 - 0.018 14.6 0.2 0.019 14.6 0.2 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ACT_5 PF13710.6 EGG42198.1 - 0.1 12.4 0.7 5.9 6.8 0.0 2.1 2 0 0 2 2 2 0 ACT domain GCV_T PF01571.21 EGG42198.1 - 0.2 11.0 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain RMMBL PF07521.12 EGG42200.1 - 0.0056 16.6 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Response_reg PF00072.24 EGG42201.1 - 8.7e-20 71.0 0.1 1.1e-19 70.7 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF1188 PF06690.11 EGG42201.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1188) Mur_ligase PF01225.25 EGG42201.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Formyl_trans_N PF00551.19 EGG42202.1 - 4.5e-48 163.4 0.0 5.1e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Cupin_2 PF07883.11 EGG42203.1 - 3.6e-09 36.2 0.0 3.9e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.8 EGG42203.1 - 1.8e-05 24.9 0.0 1.9e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 EGG42203.1 - 0.00079 19.3 0.0 0.00088 19.2 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Pirin_C PF05726.13 EGG42203.1 - 0.0087 16.4 0.0 0.011 16.1 0.0 1.0 1 0 0 1 1 1 1 Pirin C-terminal cupin domain 3-HAO PF06052.12 EGG42203.1 - 0.016 14.8 0.1 0.022 14.4 0.1 1.3 1 1 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Ectoine_synth PF06339.12 EGG42203.1 - 0.026 14.7 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Ectoine synthase Auxin_BP PF02041.16 EGG42203.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein ABM PF03992.16 EGG42204.1 - 1.4e-06 28.3 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 EGG42204.1 - 0.016 15.6 0.0 0.021 15.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1330) THF_DHG_CYH_C PF02882.19 EGG42205.1 - 8.5e-59 197.4 0.8 1.3e-58 196.9 0.8 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGG42205.1 - 1e-38 132.2 0.9 1e-38 132.2 0.9 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 EGG42205.1 - 0.0015 17.9 0.9 0.002 17.5 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Hydrolase PF00702.26 EGG42205.1 - 0.0062 16.8 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1884 PF08967.10 EGG42205.1 - 0.087 13.1 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1884) DUF3783 PF12646.7 EGG42205.1 - 0.12 12.3 1.2 8.7 6.4 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3783) Sacchrp_dh_NADP PF03435.18 EGG42205.1 - 0.2 11.9 2.2 0.37 11.1 0.1 2.4 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain 5-FTHF_cyc-lig PF01812.20 EGG42206.1 - 1.8e-20 73.5 0.0 2e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GARS_A PF01071.19 EGG42207.1 - 1.7e-34 119.3 0.1 2.2e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C PF02843.16 EGG42207.1 - 3.5e-29 100.9 0.0 5.2e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain GARS_N PF02844.15 EGG42208.1 - 1.2e-33 115.7 0.0 2.3e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_A PF01071.19 EGG42208.1 - 9.4e-23 81.0 0.3 1.4e-22 80.4 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 EGG42208.1 - 3.2e-06 26.8 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 EGG42208.1 - 6.6e-05 22.6 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EGG42208.1 - 0.00022 20.9 0.1 0.00034 20.3 0.1 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 EGG42208.1 - 0.002 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 EGG42208.1 - 0.008 15.5 0.1 0.01 15.1 0.1 1.1 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 EGG42208.1 - 0.024 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Phage_TAC_9 PF10876.8 EGG42208.1 - 0.067 13.3 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC ATP-grasp_5 PF13549.6 EGG42208.1 - 0.08 12.4 0.0 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain tRNA-synt_1 PF00133.22 EGG42209.1 - 1.7e-137 459.2 0.4 2.6e-137 458.6 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG42209.1 - 2.2e-31 108.9 1.2 5.7e-31 107.5 1.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG42209.1 - 2.1e-24 86.0 0.0 1.6e-10 40.3 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGG42209.1 - 1.7e-05 24.4 0.0 0.0005 19.5 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGG42209.1 - 0.00088 18.3 0.5 0.0043 16.0 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (K) POTRA PF07244.15 EGG42209.1 - 0.082 13.5 0.6 1.3 9.7 0.1 3.0 2 0 0 2 2 2 0 Surface antigen variable number repeat UL11 PF11094.8 EGG42209.1 - 0.36 10.7 2.8 1.1 9.2 1.1 2.6 2 0 0 2 2 2 0 Membrane-associated tegument protein Ferritin PF00210.24 EGG42210.1 - 6.1e-22 78.1 0.0 8.5e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain PH_18 PF18469.1 EGG42211.1 - 0.0018 18.2 0.5 0.0064 16.5 0.5 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain DeoC PF01791.9 EGG42211.1 - 0.035 13.7 0.0 0.04 13.5 0.0 1.0 1 0 0 1 1 1 0 DeoC/LacD family aldolase tRNA_bind PF01588.20 EGG42211.1 - 0.05 13.7 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative tRNA binding domain ATP-grasp_2 PF08442.10 EGG42212.1 - 3.3e-46 157.4 1.0 6e-46 156.6 1.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGG42212.1 - 2.1e-15 56.9 1.3 2.7e-15 56.5 0.3 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EGG42212.1 - 6.7e-14 51.9 0.1 2e-13 50.3 0.1 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGG42212.1 - 1.1e-05 25.0 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EGG42212.1 - 0.024 14.2 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain CoA_binding PF02629.19 EGG42213.1 - 2.7e-22 79.2 2.9 4.3e-22 78.6 1.7 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGG42213.1 - 1.2e-08 34.9 0.2 2.1e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.6 EGG42213.1 - 1.5e-05 25.5 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 EGG42213.1 - 7.7e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 EGG42213.1 - 0.013 16.4 0.1 0.023 15.5 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ribul_P_3_epim PF00834.19 EGG42213.1 - 0.032 13.6 0.1 0.054 12.9 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Med28 PF11594.8 EGG42214.1 - 0.071 13.2 0.1 0.12 12.5 0.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit 28 TPR_14 PF13428.6 EGG42214.1 - 0.12 13.3 0.7 0.24 12.3 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Response_reg PF00072.24 EGG42216.1 - 1.7e-21 76.5 0.7 1.9e-21 76.4 0.7 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Amidohydro_3 PF07969.11 EGG42219.1 - 2.5e-10 40.4 0.1 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Kazal_1 PF00050.21 EGG42219.1 - 1.3e-08 34.7 1.0 1.3e-08 34.7 1.0 1.8 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 EGG42219.1 - 7.3e-07 29.2 0.9 1.5e-06 28.2 0.9 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Amidohydro_1 PF01979.20 EGG42219.1 - 4.1e-05 23.1 1.5 0.28 10.4 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGG42220.1 - 2.2e-31 109.5 0.3 3.2e-31 108.9 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG42220.1 - 3.1e-08 33.5 1.7 1.6e-05 24.5 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase family DUF1059 PF06348.11 EGG42221.1 - 3.1e-07 30.5 0.1 3.6e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) FliG_N PF14842.6 EGG42221.1 - 0.07 13.7 0.1 0.083 13.4 0.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain AAA_lid_9 PF17871.1 EGG42221.1 - 0.089 12.7 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 AAA lid domain Acyl_transf_3 PF01757.22 EGG42222.1 - 0.44 9.6 26.5 0.5 9.4 16.6 2.1 1 1 1 2 2 2 0 Acyltransferase family YhfC PF10086.9 EGG42222.1 - 1.7 8.0 7.8 2.1 7.7 1.4 2.3 2 0 0 2 2 2 0 YhfC intramembrane metalloprotease CBS PF00571.28 EGG42224.1 - 4.2e-35 120.0 10.3 1.3e-08 35.1 0.0 4.2 4 0 0 4 4 4 4 CBS domain Pyrophosphatase PF00719.19 EGG42226.1 - 7.6e-56 188.3 0.1 8.9e-56 188.1 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Peptidase_M3 PF01432.20 EGG42227.1 - 1.1e-45 156.8 0.4 4.6e-45 154.7 0.4 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 EGG42227.1 - 1.7e-05 25.0 4.8 3.2e-05 24.1 0.2 3.7 4 1 0 4 4 4 1 Oligopeptidase F Peptidase_M78 PF06114.13 EGG42227.1 - 0.0036 17.2 0.1 0.0086 16.0 0.1 1.7 1 1 0 1 1 1 1 IrrE N-terminal-like domain Colicin PF01024.19 EGG42227.1 - 0.087 12.7 1.5 0.69 9.8 0.2 2.5 2 0 0 2 2 2 0 Colicin pore forming domain FG-GAP_2 PF14312.6 EGG42227.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 FG-GAP repeat DUF3198 PF11433.8 EGG42227.1 - 1.4 8.8 5.6 14 5.6 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3198) PvlArgDC PF01862.16 EGG42229.1 - 5.7e-57 192.0 0.0 6.5e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) CPBP PF02517.16 EGG42230.1 - 0.006 16.9 2.5 0.006 16.9 2.5 3.1 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease FSAP_sig_propep PF03032.15 EGG42231.1 - 4.7 7.3 5.1 0.87 9.7 1.4 1.6 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide Thioredoxin_4 PF13462.6 EGG42232.1 - 3.1e-40 138.1 0.1 6.1e-40 137.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 EGG42232.1 - 1.8e-20 73.6 0.5 1.7e-18 67.1 0.5 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EGG42232.1 - 7.3e-11 42.5 0.1 2.3e-10 40.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 EGG42232.1 - 0.038 13.7 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DEAD PF00270.29 EGG42233.1 - 5.8e-13 49.0 0.1 6.8e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD PF00270.29 EGG42234.1 - 1.7e-30 106.1 0.0 1.3e-29 103.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG42234.1 - 2.9e-30 104.9 0.1 1.2e-29 102.9 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGG42234.1 - 8.6e-06 25.1 0.2 1.2e-05 24.6 0.2 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGG42234.1 - 0.0079 15.6 0.3 0.028 13.7 0.1 2.0 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AsnC_trans_reg PF01037.21 EGG42235.1 - 2.3e-08 33.9 0.1 2.4e-08 33.8 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GYD PF08734.11 EGG42235.1 - 7e-05 22.7 0.1 7.7e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 GYD domain RecO_N_2 PF13114.6 EGG42235.1 - 0.0023 17.6 0.1 0.0028 17.3 0.1 1.1 1 0 0 1 1 1 1 RecO N terminal TPP_enzyme_N PF02776.18 EGG42236.1 - 1e-54 184.8 0.0 8.2e-53 178.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGG42236.1 - 2.1e-39 134.7 0.0 6.7e-39 133.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG42236.1 - 9.8e-32 109.6 0.3 2.1e-31 108.5 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 EGG42236.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Lig_C PF18330.1 EGG42237.1 - 0.056 13.4 2.7 0.07 13.1 2.7 1.2 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF5617 PF18493.1 EGG42237.1 - 0.11 12.6 6.2 0.32 11.1 6.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5617) DED PF01335.21 EGG42237.1 - 0.16 12.3 4.7 0.3 11.4 4.7 1.5 1 1 0 1 1 1 0 Death effector domain IQCJ-SCHIP1 PF15157.6 EGG42237.1 - 0.51 10.2 7.0 0.29 11.0 2.5 2.0 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF3573 PF12097.8 EGG42237.1 - 0.83 8.4 4.3 0.97 8.2 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Amidohydro_2 PF04909.14 EGG42238.1 - 9e-35 120.8 0.1 1.8e-34 119.9 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EGG42238.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family Acetyltransf_1 PF00583.25 EGG42239.1 - 2.1e-07 31.2 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EGG42239.1 - 2.1e-07 31.0 0.0 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG42239.1 - 0.0011 19.4 0.1 0.0042 17.5 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Fur_reg_FbpB PF13040.6 EGG42240.1 - 0.038 13.5 0.9 0.11 12.1 0.9 1.8 1 0 0 1 1 1 0 Fur-regulated basic protein B SHOCT PF09851.9 EGG42241.1 - 4.1e-08 32.7 4.3 6e-08 32.2 4.3 1.3 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.12 EGG42241.1 - 0.02 14.9 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 Gas vesicle protein G DMAP_binding PF06464.11 EGG42241.1 - 0.17 12.7 2.4 0.18 12.6 1.6 1.5 1 1 0 1 1 1 0 DMAP1-binding Domain Coiled-coil_56 PF09813.9 EGG42242.1 - 0.054 13.5 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 MS_channel PF00924.18 EGG42243.1 - 5.9e-11 42.3 1.8 1.2e-10 41.3 1.8 1.4 1 1 0 1 1 1 1 Mechanosensitive ion channel DUF768 PF05589.11 EGG42244.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF768) MS_channel PF00924.18 EGG42245.1 - 8.3e-28 97.3 0.0 1.9e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF1774 PF08611.10 EGG42245.1 - 0.034 14.5 0.6 0.1 12.9 0.6 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) HupE_UreJ_2 PF13795.6 EGG42245.1 - 0.076 12.7 0.3 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 HupE / UreJ protein LMF1 PF06762.14 EGG42245.1 - 0.12 11.5 0.3 0.18 10.8 0.3 1.2 1 0 0 1 1 1 0 Lipase maturation factor Ninjurin PF04923.12 EGG42245.1 - 0.14 12.1 1.1 1.4 8.9 1.4 2.1 2 0 0 2 2 2 0 Ninjurin Radical_SAM PF04055.21 EGG42246.1 - 2.4e-05 24.8 0.1 0.00016 22.1 0.1 2.5 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EGG42246.1 - 0.00096 19.4 0.1 0.0021 18.3 0.1 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGG42246.1 - 0.005 17.0 0.0 0.019 15.1 0.0 1.9 1 1 1 2 2 2 1 4Fe-4S single cluster domain Gln-synt_C PF00120.24 EGG42247.1 - 7e-116 387.0 0.0 8.4e-116 386.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGG42247.1 - 4.3e-24 84.1 0.2 8.8e-24 83.1 0.2 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Response_reg PF00072.24 EGG42248.1 - 1.9e-11 44.1 0.1 2.2e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain YnfE PF17452.2 EGG42248.1 - 0.0011 19.2 0.1 0.054 13.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized YnfE-like DUF1176 PF06674.11 EGG42249.1 - 0.00034 20.2 1.8 0.00054 19.5 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1176) Na_H_Exchanger PF00999.21 EGG42250.1 - 5.8e-51 173.5 55.3 7.2e-51 173.1 55.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CBS PF00571.28 EGG42250.1 - 8.2e-13 48.6 0.7 1.5e-06 28.5 0.1 2.7 2 0 0 2 2 2 2 CBS domain Pox_RNA_Pol_22 PF05273.13 EGG42253.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus RNA polymerase 22 kDa subunit Arcadin_1 PF18653.1 EGG42255.1 - 0.0024 17.9 0.9 0.0031 17.6 0.9 1.2 1 0 0 1 1 1 1 Arcadin 1 Thioredox_DsbH PF03190.15 EGG42256.1 - 8.8e-77 256.6 0.1 1.6e-76 255.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EGG42256.1 - 3.4e-10 40.0 0.0 6.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 EGG42256.1 - 2e-09 37.2 3.0 0.15 11.5 0.0 4.2 4 0 0 4 4 4 3 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 EGG42256.1 - 1.5e-06 27.6 0.1 0.34 9.9 0.0 3.8 2 2 1 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EGG42256.1 - 0.00047 18.8 0.2 1.4 7.3 0.0 3.1 2 1 0 3 3 3 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 EGG42256.1 - 0.0034 17.0 0.0 4.6 6.7 0.0 3.1 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 EGG42256.1 - 0.0081 15.4 0.0 13 4.9 0.0 3.4 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Thioredoxin_2 PF13098.6 EGG42256.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain PP_kinase_N PF13089.6 EGG42257.1 - 0.00086 19.6 0.6 0.00094 19.5 0.6 1.0 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain LPD25 PF18840.1 EGG42257.1 - 0.028 15.0 0.3 0.03 14.9 0.3 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 EamA PF00892.20 EGG42258.1 - 3e-41 140.8 34.1 9.4e-23 80.9 15.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGG42258.1 - 3.7e-07 29.8 23.1 7.7e-06 25.4 23.6 2.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 EGG42258.1 - 0.00049 19.4 8.5 0.00049 19.4 8.5 2.3 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport TMEM234 PF10639.9 EGG42258.1 - 0.0014 18.6 12.2 0.0075 16.3 1.5 2.5 2 1 0 2 2 2 2 Putative transmembrane family 234 CRT-like PF08627.10 EGG42258.1 - 0.011 14.8 23.1 0.077 11.9 11.5 2.3 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 EGG42258.1 - 0.18 11.4 21.9 0.029 14.0 6.2 2.7 1 1 2 3 3 3 0 Putative multidrug resistance efflux transporter HTH_AsnC-type PF13404.6 EGG42260.1 - 0.00017 21.4 3.7 0.00053 19.8 3.7 1.8 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EGG42260.1 - 0.00081 18.9 4.7 0.059 12.9 0.6 2.7 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding DM13 PF10517.9 EGG42262.1 - 2.4e-15 57.0 0.0 6.8e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Electron transfer DM13 Med9 PF07544.13 EGG42263.1 - 0.0002 21.4 8.1 0.013 15.6 0.3 2.9 2 1 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.11 EGG42263.1 - 0.00069 19.9 7.2 0.11 12.7 1.1 2.4 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) DUF4140 PF13600.6 EGG42263.1 - 0.00094 19.6 8.6 0.094 13.2 0.6 3.9 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) HSBP1 PF06825.12 EGG42263.1 - 0.0014 18.4 0.1 0.26 11.1 0.1 2.7 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Prefoldin_2 PF01920.20 EGG42263.1 - 0.0023 17.8 7.3 0.46 10.5 0.3 4.2 4 0 0 4 4 4 1 Prefoldin subunit Snapin_Pallidin PF14712.6 EGG42263.1 - 0.0028 18.0 4.4 0.25 11.8 0.1 2.6 2 0 0 2 2 2 1 Snapin/Pallidin TcpS PF17456.2 EGG42263.1 - 0.0044 17.1 5.6 0.14 12.2 2.0 2.7 2 0 0 2 2 2 1 Toxin-coregulated pilus protein S DUF848 PF05852.11 EGG42263.1 - 0.0085 16.2 5.4 0.21 11.7 0.7 2.4 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) ABC_tran_CTD PF16326.5 EGG42263.1 - 0.012 15.9 4.1 0.42 10.9 0.0 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain PI3K_P85_iSH2 PF16454.5 EGG42263.1 - 0.014 15.0 6.5 2.1 7.9 1.8 3.0 2 2 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NleF_casp_inhib PF16809.5 EGG42263.1 - 0.019 14.9 12.1 1.3 9.0 0.3 3.5 2 1 1 3 3 3 0 NleF caspase inhibitor LPP PF04728.13 EGG42263.1 - 0.027 14.9 2.9 14 6.2 0.1 4.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 EGG42263.1 - 0.047 14.1 8.8 1.3 9.5 0.4 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 EGG42263.1 - 0.055 14.0 1.0 3.6 8.1 0.2 2.5 2 0 0 2 2 2 0 Spectrin repeat Sacchrp_dh_NADP PF03435.18 EGG42263.1 - 0.067 13.4 0.6 0.45 10.8 0.2 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shugoshin_N PF07558.11 EGG42263.1 - 0.069 13.0 11.7 0.079 12.8 0.1 4.0 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region MHCassoc_trimer PF08831.10 EGG42263.1 - 0.08 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain DUF1137 PF06587.11 EGG42263.1 - 0.081 13.0 0.1 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) FliJ PF02050.16 EGG42263.1 - 0.09 13.0 1.2 2.7 8.2 0.0 2.6 2 1 1 3 3 3 0 Flagellar FliJ protein TraF_2 PF13729.6 EGG42263.1 - 0.1 11.9 1.3 1.3 8.3 0.1 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF4094 PF13334.6 EGG42263.1 - 0.14 12.6 12.4 0.38 11.2 0.6 4.2 5 0 0 5 5 4 0 Domain of unknown function (DUF4094) ACCA PF03255.14 EGG42263.1 - 0.15 11.9 3.1 8.5 6.2 0.3 2.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.12 EGG42263.1 - 0.18 11.9 10.9 0.51 10.4 1.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 EGG42263.1 - 0.21 11.7 6.8 9.8 6.4 2.0 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 FlxA PF14282.6 EGG42263.1 - 0.34 10.9 11.2 3.1 7.8 1.8 3.3 2 2 0 2 2 2 0 FlxA-like protein LUC7 PF03194.15 EGG42263.1 - 0.54 9.9 4.9 0.6 9.7 0.8 2.2 2 0 0 2 2 2 0 LUC7 N_terminus Lzipper-MIP1 PF14389.6 EGG42263.1 - 0.66 10.3 4.6 57 4.1 0.0 3.1 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Uso1_p115_C PF04871.13 EGG42263.1 - 0.66 10.4 7.3 5.5 7.4 0.5 3.2 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.22 EGG42263.1 - 0.71 10.1 10.0 1.8 8.8 1.6 3.3 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Lectin_N PF03954.14 EGG42263.1 - 1.4 8.7 7.0 2.7 7.7 0.4 2.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Tropomyosin_1 PF12718.7 EGG42263.1 - 2.3 8.4 11.9 1 9.5 0.9 2.5 2 1 0 2 2 2 0 Tropomyosin like CdvA PF18822.1 EGG42263.1 - 3 7.7 9.6 2.2 8.1 2.0 2.7 2 2 0 2 2 2 0 CdvA-like coiled-coil domain DUF1192 PF06698.11 EGG42263.1 - 3.2 7.9 6.7 29 4.8 0.5 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) CCDC-167 PF15188.6 EGG42263.1 - 3.5 8.0 11.2 11 6.4 0.2 3.5 2 2 2 4 4 4 0 Coiled-coil domain-containing protein 167 BST2 PF16716.5 EGG42263.1 - 3.8 8.2 13.6 2.4 8.8 0.7 3.9 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 EGG42263.1 - 5.9 7.0 13.4 6.7 6.8 1.1 3.8 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.6 EGG42265.1 - 0.035 14.5 7.5 0.047 14.1 0.7 2.8 2 2 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SH3BP5 PF05276.14 EGG42265.1 - 0.039 13.8 2.0 0.074 12.8 0.3 2.0 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) 4HFCP_synth PF04476.13 EGG42265.1 - 0.04 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 4-HFC-P synthase I_LWEQ PF01608.17 EGG42265.1 - 0.04 14.2 4.6 0.74 10.0 0.2 2.5 2 0 0 2 2 2 0 I/LWEQ domain CC2-LZ PF16516.5 EGG42265.1 - 0.059 13.7 5.0 2.7 8.4 1.0 2.5 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Polysacc_synt_2 PF02719.15 EGG42265.1 - 0.069 12.3 0.0 4.5 6.3 0.0 2.8 2 1 0 3 3 3 0 Polysaccharide biosynthesis protein Snapin_Pallidin PF14712.6 EGG42265.1 - 0.099 13.1 11.6 0.071 13.5 3.7 3.2 3 0 0 3 3 3 0 Snapin/Pallidin LidA_Long_CC PF18641.1 EGG42265.1 - 0.38 10.8 7.8 0.042 13.9 2.7 2.0 2 0 0 2 2 2 0 LidA long coiled-coil domain OmpH PF03938.14 EGG42265.1 - 0.73 10.2 6.9 4 7.8 0.2 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 EGG42265.1 - 1.4 7.9 8.5 0.72 8.9 2.9 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 EGG42265.1 - 2.1 8.6 9.1 2.7 8.3 3.4 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MscS_porin PF12795.7 EGG42265.1 - 2.5 7.6 14.2 0.8 9.2 1.4 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain FAM76 PF16046.5 EGG42265.1 - 2.7 7.3 6.0 5.3 6.3 0.5 2.3 2 0 0 2 2 2 0 FAM76 protein DUF724 PF05266.14 EGG42265.1 - 3.3 7.5 7.4 7.5 6.3 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 EGG42265.1 - 5 7.4 8.5 7.9 6.8 0.5 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 EGG42265.1 - 6.1 7.0 12.2 1e+02 3.1 8.4 3.5 3 1 0 3 3 3 0 TolA binding protein trimerisation Response_reg PF00072.24 EGG42266.1 - 4.7e-23 81.5 1.5 5.4e-23 81.3 1.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain LMWPc PF01451.21 EGG42267.1 - 1.6e-22 80.4 0.2 3.3e-22 79.4 0.2 1.5 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ADH_N PF08240.12 EGG42268.1 - 7.8e-18 64.4 0.3 9.6e-18 64.1 0.3 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG42270.1 - 2.3e-06 27.6 0.0 2.3e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG42271.1 - 0.0013 19.8 0.0 0.0015 19.6 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG42271.1 - 0.0048 16.9 0.0 0.0068 16.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TssC PF17541.2 EGG42271.1 - 0.026 13.3 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB DUF4443 PF14544.6 EGG42271.1 - 0.031 14.5 0.0 0.033 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) AAA_33 PF13671.6 EGG42272.1 - 3.7e-14 53.1 0.0 4.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG42272.1 - 0.00084 19.9 1.2 0.0016 19.0 1.2 1.6 1 1 0 1 1 1 1 AAA domain DUF3791 PF12668.7 EGG42272.1 - 0.0021 18.0 0.3 0.0065 16.5 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3791) UDPG_MGDP_dh PF00984.19 EGG42272.1 - 0.0064 16.7 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain AAA_17 PF13207.6 EGG42272.1 - 0.0087 16.5 0.2 0.017 15.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain ARL2_Bind_BART PF11527.8 EGG42272.1 - 0.016 15.3 0.8 0.027 14.6 0.3 1.6 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART DUF5621 PF18532.1 EGG42272.1 - 0.051 13.5 0.7 0.13 12.1 0.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5621) SRP54 PF00448.22 EGG42272.1 - 0.18 11.4 0.4 1.3 8.7 0.4 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EGG42272.1 - 0.2 11.4 0.8 0.5 10.1 0.2 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Zn_ribbon_SprT PF17283.2 EGG42273.1 - 3.5e-05 23.6 8.6 0.035 14.0 0.7 2.3 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Molybdop_Fe4S4 PF04879.16 EGG42273.1 - 0.0046 16.9 8.0 0.39 10.7 0.9 2.3 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Fe4S4 domain DNA_RNApol_7kD PF03604.13 EGG42273.1 - 0.0087 15.7 15.8 0.44 10.3 4.0 2.7 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_6 PF14599.6 EGG42273.1 - 0.031 14.3 10.8 0.45 10.6 1.7 2.9 2 2 1 3 3 3 0 Zinc-ribbon DUF866 PF05907.13 EGG42273.1 - 0.18 11.7 0.8 11 5.9 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) DUF1059 PF06348.11 EGG42273.1 - 0.76 10.1 4.5 15 5.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) LIM PF00412.22 EGG42273.1 - 3 8.1 12.8 7.3 6.9 2.5 2.3 2 0 0 2 2 2 0 LIM domain SCIFF PF13165.6 EGG42273.1 - 4.2 7.4 10.8 7.6 6.6 0.3 3.3 4 0 0 4 4 4 0 Six-cysteine peptide SCIFF Elf1 PF05129.13 EGG42273.1 - 6.5 6.9 11.1 3.8 7.6 0.1 3.0 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like DUF2196 PF09962.9 EGG42274.1 - 2.4e-29 101.1 2.0 2.5e-29 101.0 2.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) PhoU PF01895.19 EGG42275.1 - 2.4e-19 69.6 5.5 2.2e-09 37.6 0.1 2.3 2 0 0 2 2 2 2 PhoU domain ABC_tran PF00005.27 EGG42276.1 - 1.5e-30 106.5 0.0 2.1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG42276.1 - 5e-12 46.3 0.0 9.9e-05 22.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG42276.1 - 2.9e-10 40.0 0.0 5.8e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGG42276.1 - 4.7e-06 26.6 1.4 4.9e-05 23.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG42276.1 - 1.9e-05 24.9 0.0 5e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGG42276.1 - 0.00013 22.6 0.1 0.00037 21.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGG42276.1 - 0.00031 20.7 0.1 0.00064 19.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EGG42276.1 - 0.0008 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EGG42276.1 - 0.0011 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 EGG42276.1 - 0.0019 17.4 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_30 PF13604.6 EGG42276.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGG42276.1 - 0.0087 15.3 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGG42276.1 - 0.0095 16.3 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGG42276.1 - 0.012 15.6 1.2 0.29 11.0 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGG42276.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG42276.1 - 0.026 15.1 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGG42276.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 EGG42276.1 - 0.028 13.8 0.5 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 EGG42276.1 - 0.034 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGG42276.1 - 0.036 13.8 0.3 0.086 12.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGG42276.1 - 0.049 13.8 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGG42276.1 - 0.059 13.8 1.8 0.66 10.4 0.1 2.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGG42276.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 EGG42276.1 - 0.098 13.0 0.3 0.3 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGG42276.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 EGG42277.1 - 1.2e-17 64.2 21.7 1.5e-17 64.0 15.7 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.8 EGG42277.1 - 0.21 11.8 3.1 0.26 11.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Ost4 PF10215.9 EGG42277.1 - 2.4 8.0 6.5 0.53 10.1 1.1 2.6 2 0 0 2 2 2 0 Oligosaccaryltransferase BPD_transp_1 PF00528.22 EGG42278.1 - 7.6e-17 61.6 16.1 7.6e-17 61.6 16.1 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF1011 PF06237.12 EGG42278.1 - 0.58 10.5 4.9 10 6.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1011) PhoU PF01895.19 EGG42279.1 - 1e-20 74.0 13.7 2.9e-17 62.9 3.5 2.6 3 0 0 3 3 3 2 PhoU domain MazE_antitoxin PF04014.18 EGG42279.1 - 1.2e-05 25.1 0.0 3.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin SpoVG PF04026.12 EGG42279.1 - 0.017 15.3 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 SpoVG SeqA_N PF17206.3 EGG42279.1 - 0.093 12.1 1.7 0.82 9.0 0.2 3.0 3 0 0 3 3 3 0 SeqA protein N-terminal domain PBP_like_2 PF12849.7 EGG42281.1 - 8.3e-55 186.4 0.8 1.1e-54 186.0 0.8 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 EGG42281.1 - 1.4e-13 51.5 1.1 1.7e-13 51.2 0.5 1.6 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 EGG42281.1 - 1.9e-08 33.7 0.0 7.1e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 PBP superfamily domain MutS_II PF05188.17 EGG42282.1 - 0.013 15.7 0.1 0.015 15.5 0.1 1.1 1 0 0 1 1 1 0 MutS domain II DUF2018 PF09442.10 EGG42282.1 - 0.025 15.5 0.8 0.032 15.2 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2018) Lar_restr_allev PF14354.6 EGG42283.1 - 0.00019 21.7 2.3 0.00019 21.7 2.3 2.0 2 0 0 2 2 2 1 Restriction alleviation protein Lar Tmemb_55A PF09788.9 EGG42283.1 - 0.0043 16.2 1.3 0.0054 15.8 1.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A DUF2310 PF10071.9 EGG42283.1 - 0.0083 15.4 0.5 0.014 14.7 0.5 1.3 1 0 0 1 1 1 1 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Elf1 PF05129.13 EGG42283.1 - 0.014 15.4 2.4 0.032 14.3 2.4 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.6 EGG42283.1 - 0.039 13.7 1.2 0.085 12.6 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_7 PF02591.15 EGG42283.1 - 0.093 12.9 3.4 2.7 8.2 0.1 2.8 3 0 0 3 3 3 0 C4-type zinc ribbon domain OrfB_Zn_ribbon PF07282.11 EGG42283.1 - 0.12 12.4 4.4 0.27 11.2 3.2 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 EGG42283.1 - 0.41 10.2 8.9 0.12 12.0 5.6 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.13 EGG42283.1 - 0.48 10.1 8.6 0.29 10.9 5.4 2.3 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF2177 PF09945.9 EGG42285.1 - 0.12 12.5 8.4 2.7 8.1 2.6 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2177) DUF2101 PF09874.9 EGG42286.1 - 0.03 14.0 0.4 0.035 13.8 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) SdpI PF13630.6 EGG42286.1 - 0.11 12.6 4.1 0.18 11.9 4.1 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF5455 PF17537.2 EGG42286.1 - 0.16 12.4 3.1 0.23 11.9 3.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5455) DUF2583 PF10762.9 EGG42286.1 - 2.6 8.5 5.8 5 7.6 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2583) DUF2371 PF10177.9 EGG42286.1 - 7.7 6.7 7.5 0.82 9.8 1.2 2.1 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) AsnC_trans_reg PF01037.21 EGG42287.1 - 7.5e-10 38.6 0.1 7.8e-10 38.6 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain TruD PF01142.18 EGG42288.1 - 5.5e-90 302.2 3.1 3.3e-89 299.6 3.1 1.8 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) ATP13 PF12921.7 EGG42288.1 - 0.06 13.2 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 Mitochondrial ATPase expression SGL PF08450.12 EGG42289.1 - 3.8e-09 36.5 0.8 0.24 10.9 0.0 4.4 2 2 1 4 4 4 4 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EGG42289.1 - 1.7e-05 24.6 0.0 0.00078 19.4 0.0 3.0 2 0 0 2 2 2 1 NHL repeat DUF5074 PF16819.5 EGG42289.1 - 6.1e-05 23.0 0.9 3.2 7.8 0.1 4.4 4 1 0 4 4 4 2 Domain of unknown function (DUF5074) Phytase-like PF13449.6 EGG42289.1 - 0.016 15.2 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Esterase-like activity of phytase Str_synth PF03088.16 EGG42289.1 - 0.047 13.8 0.0 18 5.5 0.0 3.4 2 1 1 3 3 3 0 Strictosidine synthase alpha-hel2 PF14456.6 EGG42289.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Reg_prop PF07494.11 EGG42289.1 - 0.094 13.0 6.4 27 5.4 0.0 4.8 5 0 0 5 5 5 0 Two component regulator propeller PTH2 PF01981.16 EGG42290.1 - 1.1e-39 135.3 0.0 1.2e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF1610 PF07754.11 EGG42291.1 - 5.3e-05 23.1 9.5 5.3e-05 23.1 9.5 3.0 4 0 0 4 4 4 2 Domain of unknown function (DUF1610) zf-CHY PF05495.12 EGG42291.1 - 0.037 14.5 17.1 0.042 14.3 17.1 1.2 1 0 0 1 1 1 0 CHY zinc finger zf-ribbon_3 PF13248.6 EGG42291.1 - 0.058 12.8 0.2 0.058 12.8 0.2 3.7 4 1 0 4 4 4 0 zinc-ribbon domain EF1_GNE PF00736.19 EGG42292.1 - 2.8e-16 59.5 0.3 3e-16 59.3 0.3 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF4390 PF14334.6 EGG42292.1 - 0.15 11.5 0.0 13 5.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) AAA PF00004.29 EGG42293.1 - 3.1e-91 302.7 0.2 4.9e-48 162.9 0.0 3.1 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG42293.1 - 4.7e-32 109.5 3.6 3.4e-15 55.6 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGG42293.1 - 3.7e-27 94.3 0.8 1.5e-26 92.4 0.8 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGG42293.1 - 1.1e-15 57.7 1.5 1.1e-08 35.0 0.0 3.6 3 1 2 5 5 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG42293.1 - 3.5e-13 50.0 0.0 1.3e-07 31.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGG42293.1 - 1.1e-12 48.6 0.2 0.0032 17.9 0.0 4.8 2 2 2 4 4 4 2 AAA ATPase domain AAA_14 PF13173.6 EGG42293.1 - 9.9e-12 45.0 0.0 3.6e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGG42293.1 - 1.1e-10 41.6 0.4 0.00037 20.5 0.0 4.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG42293.1 - 1.6e-10 41.3 0.1 0.03 14.6 0.0 4.5 3 1 1 4 4 4 2 AAA domain RNA_helicase PF00910.22 EGG42293.1 - 1.6e-09 38.1 0.0 0.0017 18.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase CDC48_2 PF02933.17 EGG42293.1 - 2.6e-09 36.7 0.2 1.1e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATPase_2 PF01637.18 EGG42293.1 - 7.8e-09 35.8 0.0 0.004 17.1 0.0 3.5 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGG42293.1 - 1.3e-08 34.7 1.2 0.22 11.1 0.0 4.8 5 1 1 6 6 5 2 AAA domain ABC_tran PF00005.27 EGG42293.1 - 1.7e-08 35.0 0.1 0.011 16.3 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 EGG42293.1 - 2.2e-08 34.4 0.0 0.004 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGG42293.1 - 2.4e-08 34.6 0.0 0.0041 17.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EGG42293.1 - 6.2e-08 32.8 0.4 0.026 14.4 0.0 3.6 3 2 0 3 3 3 2 Rad17 P-loop domain AAA_24 PF13479.6 EGG42293.1 - 6.8e-07 29.2 0.1 0.11 12.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EGG42293.1 - 7.8e-07 28.7 0.4 0.018 14.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGG42293.1 - 9.8e-07 29.2 0.0 0.076 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 EGG42293.1 - 1.6e-06 28.3 0.0 0.1 12.7 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGG42293.1 - 2.8e-06 27.2 0.0 0.13 12.0 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EGG42293.1 - 5.7e-06 25.8 0.0 0.019 14.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activat PF00158.26 EGG42293.1 - 1.1e-05 25.2 0.0 1 9.0 0.0 3.9 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_7 PF12775.7 EGG42293.1 - 4.9e-05 22.9 0.3 0.15 11.6 0.0 3.2 3 1 0 3 3 3 2 P-loop containing dynein motor region ATPase PF06745.13 EGG42293.1 - 5.4e-05 22.7 0.6 0.48 9.7 0.0 3.6 2 1 1 3 3 3 2 KaiC Zeta_toxin PF06414.12 EGG42293.1 - 6.3e-05 22.3 0.0 0.15 11.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 EGG42293.1 - 8.1e-05 22.6 0.4 2.1 8.3 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_11 PF13086.6 EGG42293.1 - 0.00023 21.1 0.0 0.12 12.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 EGG42293.1 - 0.00024 21.1 0.0 0.33 10.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 EGG42293.1 - 0.00037 19.8 0.0 0.6 9.3 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EGG42293.1 - 0.00038 20.3 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EGG42293.1 - 0.00049 19.6 0.5 2.2 7.7 0.1 3.7 3 0 0 3 3 3 1 PhoH-like protein AAA_17 PF13207.6 EGG42293.1 - 0.00077 19.9 0.0 2.2 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 EGG42293.1 - 0.0012 18.6 0.1 1.7 8.2 0.0 3.2 2 1 1 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.11 EGG42293.1 - 0.0015 18.4 0.0 3.6 7.4 0.0 3.2 4 1 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EGG42293.1 - 0.0015 18.0 0.0 2.3 7.6 0.0 3.3 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Parvo_NS1 PF01057.17 EGG42293.1 - 0.0022 17.2 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EGG42293.1 - 0.0033 16.7 0.3 2.7 7.1 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain DUF815 PF05673.13 EGG42293.1 - 0.0057 15.9 0.0 5.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) UFD1 PF03152.14 EGG42293.1 - 0.013 15.0 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Vps4_C PF09336.10 EGG42293.1 - 0.021 14.8 0.2 7 6.7 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SKI PF01202.22 EGG42293.1 - 0.032 14.4 0.1 8.3 6.5 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase KAP_NTPase PF07693.14 EGG42293.1 - 0.037 13.3 0.3 5.1 6.2 0.0 3.0 2 2 1 3 3 3 0 KAP family P-loop domain AAA_19 PF13245.6 EGG42293.1 - 0.04 14.2 1.1 12 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EGG42293.1 - 0.047 13.4 1.5 14 5.3 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase IPT PF01745.16 EGG42293.1 - 0.057 12.8 0.1 0.61 9.4 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Hydin_ADK PF17213.3 EGG42293.1 - 0.058 13.7 2.1 13 6.0 0.0 3.7 5 0 0 5 5 3 0 Hydin Adenylate kinase-like domain Adeno_IVa2 PF02456.15 EGG42293.1 - 0.062 12.1 0.1 5.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 EGG42293.1 - 0.065 13.0 0.2 24 4.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGG42293.1 - 0.084 13.4 0.1 4.2 7.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 EGG42293.1 - 0.1 12.7 0.0 9.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family SurA_N PF09312.11 EGG42296.1 - 0.017 15.2 0.2 0.17 12.0 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain ILEI PF15711.5 EGG42296.1 - 0.041 14.4 0.1 0.42 11.1 0.0 2.2 1 1 0 2 2 2 0 Interleukin-like EMT inducer HicB PF05534.12 EGG42296.1 - 0.096 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 HicB family TauE PF01925.19 EGG42298.1 - 4.8e-49 167.1 36.5 5.4e-49 166.9 36.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF5079 PF16882.5 EGG42298.1 - 3 7.7 12.0 2 8.3 6.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) Rhodanese PF00581.20 EGG42299.1 - 2.7e-26 92.2 0.0 4.4e-12 46.5 0.0 2.7 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 EGG42299.1 - 2.1e-19 70.3 0.8 9.5e-19 68.2 0.8 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 EGG42299.1 - 0.00023 20.7 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG42299.1 - 0.0042 16.6 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGG42299.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_M26_C PF07580.14 EGG42301.1 - 0.014 13.9 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region MPP6 PF10175.9 EGG42301.1 - 0.072 13.6 0.1 0.096 13.2 0.1 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 CopG_antitoxin PF12441.8 EGG42302.1 - 0.021 15.4 0.6 0.16 12.6 0.0 2.5 2 1 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system UbiA PF01040.18 EGG42303.1 - 1e-50 172.4 21.9 1.3e-50 172.0 21.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1129 PF06570.11 EGG42303.1 - 0.42 10.1 9.3 1.3 8.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Copper-bind PF00127.20 EGG42304.1 - 3.7e-15 56.2 1.0 7.2e-07 29.6 0.0 2.7 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EGG42304.1 - 9.4e-13 48.2 0.1 1.6e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain Prok-JAB PF14464.6 EGG42305.1 - 2.8e-20 72.3 0.0 3.2e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 EGG42305.1 - 5.2e-07 29.6 0.0 7.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.15 EGG42305.1 - 0.00017 21.6 0.2 0.00032 20.6 0.2 1.4 1 1 0 1 1 1 1 RadC-like JAB domain Sda PF08970.10 EGG42305.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation inhibitor A Toxin-JAB1 PF15659.6 EGG42305.1 - 0.025 14.9 0.2 0.054 13.8 0.1 1.6 1 1 1 2 2 2 0 JAB-like toxin 1 TylF PF05711.11 EGG42305.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Cyclophil_like PF04126.13 EGG42306.1 - 9.4e-38 128.7 0.0 1.1e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 EGG42306.1 - 4.4e-08 33.1 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like family NSP2_assoc PF14758.6 EGG42306.1 - 0.094 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein Methyltransf_3 PF01596.17 EGG42307.1 - 3e-37 127.9 0.6 1e-36 126.1 0.6 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGG42307.1 - 2.2e-13 51.1 0.0 4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG42307.1 - 9.8e-08 32.0 0.1 3.5e-07 30.2 0.1 1.9 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGG42307.1 - 2.7e-06 27.2 0.1 4.4e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EGG42307.1 - 8.2e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_25 PF13649.6 EGG42307.1 - 7e-05 23.5 0.0 0.00021 21.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGG42307.1 - 0.00016 21.1 0.0 0.00019 20.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 EGG42307.1 - 0.00058 19.5 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 EGG42307.1 - 0.0021 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_15 PF09445.10 EGG42307.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 EGG42307.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 EGG42307.1 - 0.036 13.2 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase UPF0020 PF01170.18 EGG42307.1 - 0.038 13.7 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GCD14 PF08704.10 EGG42307.1 - 0.062 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ARD PF03079.14 EGG42308.1 - 0.089 13.0 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 ARD/ARD' family UbiA PF01040.18 EGG42309.1 - 0.00051 19.4 12.3 0.00095 18.5 11.1 1.8 1 1 1 2 2 2 1 UbiA prenyltransferase family PrgI PF12666.7 EGG42309.1 - 2.1 9.1 11.8 0.11 13.2 0.8 3.3 2 1 1 3 3 3 0 PrgI family protein AA_permease_2 PF13520.6 EGG42310.1 - 7.3e-55 186.5 54.7 9e-55 186.2 54.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG42310.1 - 2.5e-46 158.3 51.2 3e-46 158.0 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 EGG42310.1 - 1.8e-10 40.1 19.6 1.8e-10 40.1 19.6 2.4 1 1 2 3 3 3 1 Spore germination protein AA_permease_C PF13906.6 EGG42310.1 - 5.8e-05 23.1 2.2 5.8e-05 23.1 2.2 4.0 5 0 0 5 5 5 1 C-terminus of AA_permease DUF983 PF06170.12 EGG42310.1 - 2.3 8.7 0.0 2.3 8.7 0.0 4.4 4 2 1 5 5 5 0 Protein of unknown function (DUF983) Usp PF00582.26 EGG42311.1 - 7.6e-08 33.0 0.0 8.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF711 PF05167.12 EGG42311.1 - 0.038 12.9 0.2 0.045 12.6 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) DUF389 PF04087.14 EGG42312.1 - 1.8e-30 105.8 17.1 1.8e-30 105.8 17.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF389) TssN PF17555.2 EGG42312.1 - 0.16 11.3 11.7 0.2 11.0 2.5 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF2024 PF09630.10 EGG42313.1 - 1.7e-37 127.2 1.7 1.8e-37 127.0 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2024) Haem_bd PF14376.6 EGG42313.1 - 0.029 14.3 0.1 0.033 14.1 0.1 1.1 1 0 0 1 1 1 0 Haem-binding domain H_PPase PF03030.16 EGG42315.1 - 5.3e-145 484.6 30.1 6e-145 484.4 30.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Citrate_synt PF00285.21 EGG42316.1 - 1.4e-130 435.6 0.0 1.6e-130 435.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF1940 PF09155.10 EGG42316.1 - 0.05 13.7 0.0 0.25 11.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1940) FrhB_FdhB_N PF04422.13 EGG42316.1 - 0.17 12.0 0.2 0.41 10.8 0.2 1.7 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term DUF2407_C PF13373.6 EGG42318.1 - 0.072 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain ADH_N PF08240.12 EGG42319.1 - 4.1e-24 84.6 2.5 8.7e-24 83.5 2.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG42319.1 - 7.2e-19 68.1 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGG42319.1 - 2e-11 43.8 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGG42319.1 - 1.1e-06 29.7 0.0 2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ATP-synt_F PF01990.17 EGG42320.1 - 5.2e-14 52.3 0.0 5.9e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Trp_syntA PF00290.20 EGG42320.1 - 0.00032 19.6 0.0 0.00034 19.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain LUD_dom PF02589.15 EGG42320.1 - 0.039 13.7 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 LUD domain UBA_3 PF09288.10 EGG42321.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Herpes_U55 PF06501.11 EGG42321.1 - 0.21 10.3 0.0 0.23 10.2 0.0 1.0 1 0 0 1 1 1 0 Human herpesvirus U55 protein SWIM PF04434.17 EGG42323.1 - 0.071 12.8 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 SWIM zinc finger Metallophos PF00149.28 EGG42324.1 - 2.6e-08 34.6 0.1 1.1e-07 32.5 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG42324.1 - 1.8e-06 28.3 0.0 3.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 EGG42324.1 - 0.022 13.6 0.0 0.047 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Metallophos_3 PF14582.6 EGG42324.1 - 0.046 13.0 0.1 1.1 8.6 0.1 2.3 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DNA_pol_E_B PF04042.16 EGG42324.1 - 0.086 12.2 0.0 0.54 9.6 0.0 2.3 2 1 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B CPSase_L_D2 PF02786.17 EGG42325.1 - 2.8e-103 344.0 0.0 8.7e-74 247.6 0.1 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EGG42325.1 - 6.8e-37 126.5 0.0 1.5e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EGG42325.1 - 1.7e-17 63.5 0.4 3.2e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGG42325.1 - 8.7e-16 58.1 1.0 3.9e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EGG42325.1 - 3.6e-14 52.7 0.5 5.3e-13 49.0 0.0 2.8 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.6 EGG42325.1 - 1.9e-13 50.3 0.0 2.9e-08 33.5 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EGG42325.1 - 1.7e-10 41.0 0.2 0.00023 21.0 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EGG42325.1 - 2.2e-05 24.5 1.2 0.024 14.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 EGG42325.1 - 6.8e-05 22.5 2.6 0.026 14.1 0.1 2.9 2 0 0 2 2 2 2 ATP-grasp domain TrkA_N PF02254.18 EGG42325.1 - 0.003 17.8 0.0 0.011 16.0 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain Vps5 PF09325.10 EGG42325.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Vps5 C terminal like ATP-grasp_2 PF08442.10 EGG42325.1 - 0.055 13.0 0.0 0.19 11.3 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 EGG42325.1 - 0.11 11.9 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain CPSase_sm_chain PF00988.22 EGG42326.1 - 2.7e-43 146.8 0.0 1.2e-42 144.7 0.0 2.0 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGG42326.1 - 6.7e-43 146.7 0.1 1e-42 146.1 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG42326.1 - 8.2e-08 32.3 0.3 5.4e-06 26.3 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 Thump_like PF18096.1 EGG42326.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 THUMP domain-like AAA PF00004.29 EGG42327.1 - 6.3e-38 130.2 0.0 1.4e-37 129.1 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 EGG42327.1 - 1.8e-07 31.1 0.1 3.5e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.14 EGG42327.1 - 2.4e-07 31.0 0.0 5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 EGG42327.1 - 3.9e-07 30.0 0.1 7.8e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 EGG42327.1 - 1.9e-05 25.1 0.0 0.0075 16.7 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGG42327.1 - 2.9e-05 24.4 0.0 0.0018 18.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 EGG42327.1 - 3.2e-05 23.6 0.0 9.2e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGG42327.1 - 5.4e-05 23.0 0.0 0.00014 21.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGG42327.1 - 0.00039 20.2 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGG42327.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EGG42327.1 - 0.0024 17.9 0.0 0.018 15.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EGG42327.1 - 0.0037 17.2 0.3 1.7 8.5 0.0 2.8 2 1 1 3 3 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGG42327.1 - 0.0045 17.0 0.0 0.075 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGG42327.1 - 0.0053 16.2 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGG42327.1 - 0.0069 16.6 0.0 0.03 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGG42327.1 - 0.0087 15.3 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 EGG42327.1 - 0.01 15.4 0.0 0.033 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGG42327.1 - 0.017 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGG42327.1 - 0.019 14.2 0.0 0.064 12.5 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin ATPase PF06745.13 EGG42327.1 - 0.038 13.3 0.1 1.8 7.8 0.1 2.3 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.6 EGG42327.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGG42327.1 - 0.082 12.1 0.0 1.3 8.2 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Parvo_NS1 PF01057.17 EGG42327.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EGG42327.1 - 0.12 12.7 0.0 0.44 11.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 EGG42327.1 - 0.17 11.3 0.6 0.36 10.2 0.3 1.7 2 0 0 2 2 1 0 PhoH-like protein DASH_Spc19 PF08287.11 EGG42328.1 - 0.007 16.3 1.0 0.007 16.3 1.0 1.6 2 1 0 1 1 1 1 Spc19 TrmB PF01978.19 EGG42330.1 - 6.1e-17 61.3 0.3 1e-15 57.4 0.2 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF327 PF03885.13 EGG42330.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HTH_IclR PF09339.10 EGG42330.1 - 0.16 11.8 0.1 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain YjgF_endoribonc PF14588.6 EGG42331.1 - 7.8e-32 110.5 0.0 8.4e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EGG42331.1 - 7e-23 80.9 0.0 8.7e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BON PF04972.17 EGG42331.1 - 0.012 15.9 0.4 0.27 11.6 0.1 2.6 2 1 0 2 2 2 0 BON domain MOEP19 PF16005.5 EGG42331.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 KH-like RNA-binding domain DHHA1 PF02272.19 EGG42332.1 - 6.8e-16 58.9 1.9 9.7e-16 58.4 0.4 2.1 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.20 EGG42332.1 - 0.00018 21.7 1.0 0.00038 20.6 1.0 1.5 1 0 0 1 1 1 1 DHH family HD_3 PF13023.6 EGG42332.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 HD domain Response_reg PF00072.24 EGG42334.1 - 3.2e-21 75.6 0.4 3.8e-21 75.4 0.4 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EGG42335.1 - 1.3e-25 89.8 0.5 1.5e-25 89.6 0.5 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EGG42336.1 - 4.5e-25 88.0 0.1 5.2e-25 87.8 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EGG42337.1 - 4.5e-25 88.0 0.1 1.4e-24 86.4 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGG42337.1 - 1.3e-16 61.0 2.0 1.9e-16 60.5 0.9 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EGG42337.1 - 1.5e-11 44.1 0.5 1.5e-11 44.1 0.5 2.2 2 1 0 2 2 2 1 GHKL domain HisKA PF00512.25 EGG42337.1 - 2.8e-09 36.9 1.9 6.5e-09 35.7 0.2 2.6 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EGG42337.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain FeoB_Cyto PF17910.1 EGG42337.1 - 0.71 10.5 4.5 3.5 8.2 4.5 2.3 1 1 0 1 1 1 0 FeoB cytosolic helical domain Response_reg PF00072.24 EGG42338.1 - 1.5e-25 89.5 0.3 1.8e-25 89.3 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain SeleniumBinding PF11524.8 EGG42338.1 - 0.0081 16.6 0.4 0.017 15.6 0.4 1.5 1 0 0 1 1 1 1 Selenium binding protein LTD PF00932.19 EGG42338.1 - 0.062 13.7 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Lamin Tail Domain Response_reg PF00072.24 EGG42339.1 - 2.4e-20 72.8 0.1 2.7e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EGG42340.1 - 2.5e-24 85.6 0.5 2.8e-24 85.4 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Peptidase_M10 PF00413.24 EGG42341.1 - 1.8e-11 44.1 0.0 5.2e-10 39.4 0.0 2.3 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 EGG42341.1 - 0.0017 18.0 0.4 0.0031 17.2 0.3 1.4 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 EGG42341.1 - 0.026 13.5 0.0 0.054 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 EGG42341.1 - 0.028 13.6 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 EGG42341.1 - 0.028 14.9 0.0 0.059 13.9 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Phi29_Phage_SSB PF17427.2 EGG42341.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Reprolysin_5 PF13688.6 EGG42341.1 - 0.09 12.9 0.1 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12 Astacin PF01400.24 EGG42341.1 - 0.11 12.1 0.4 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M43 PF05572.13 EGG42341.1 - 0.12 12.3 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A GN3L_Grn1 PF08701.11 EGG42345.1 - 0.19 11.8 0.2 0.3 11.2 0.2 1.2 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase TrmB PF01978.19 EGG42346.1 - 0.0023 17.8 0.0 0.0097 15.8 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB SpoOE-like PF09388.10 EGG42346.1 - 0.053 13.4 1.0 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein HTH_23 PF13384.6 EGG42346.1 - 0.17 11.7 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HEAT_2 PF13646.6 EGG42347.1 - 1.1e-08 35.4 0.1 1.3e-07 31.9 0.0 2.3 2 1 0 2 2 2 1 HEAT repeats CAS_CSE1 PF03378.15 EGG42347.1 - 0.052 12.0 0.0 0.065 11.7 0.0 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Methyltransf_21 PF05050.12 EGG42348.1 - 5.6e-17 62.3 0.1 7.9e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 EGG42348.1 - 3e-05 23.5 0.1 3.8e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_31 PF13847.6 EGG42348.1 - 0.00018 21.4 0.0 0.00047 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EGG42348.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EGG42348.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGG42348.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NitrOD1 PF18549.1 EGG42349.1 - 5.8e-46 154.3 2.3 6.4e-46 154.2 2.3 1.0 1 0 0 1 1 1 1 Nitrosopumilus output domain 1 FPRL1_inhibitor PF16104.5 EGG42349.1 - 0.062 13.4 0.1 0.089 12.9 0.1 1.2 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein DUF2418 PF10332.9 EGG42350.1 - 0.034 14.6 0.0 0.039 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) YfhO PF09586.10 EGG42351.1 - 0.15 10.2 0.2 0.22 9.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CbtA PF09490.10 EGG42353.1 - 1.3e-50 172.5 1.0 1.6e-50 172.2 1.0 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) Sugar_tr PF00083.24 EGG42353.1 - 0.38 9.6 9.1 0.28 10.0 5.0 2.1 1 1 1 2 2 2 0 Sugar (and other) transporter CbtB PF09489.10 EGG42354.1 - 4.5e-13 49.1 2.6 6.2e-13 48.6 2.6 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) Herpes_pp38 PF04846.13 EGG42354.1 - 0.13 12.2 0.4 0.19 11.6 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein DUF4443 PF14544.6 EGG42355.1 - 3.3e-05 24.1 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) HTH_45 PF14947.6 EGG42355.1 - 0.02 14.9 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix Ribosomal_S19e PF01090.19 EGG42355.1 - 0.15 11.8 0.5 0.36 10.5 0.1 1.9 2 1 0 2 2 2 0 Ribosomal protein S19e Thioredoxin_4 PF13462.6 EGG42356.1 - 9.1e-33 113.8 0.0 1.1e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EGG42356.1 - 6.1e-16 58.8 0.0 6.3e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EGG42356.1 - 9.7e-09 35.7 0.7 1.6e-08 35.0 0.7 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 EGG42356.1 - 1.2e-05 25.1 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 EGG42356.1 - 0.09 12.8 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin HIT PF01230.23 EGG42357.1 - 2.2e-23 82.8 1.5 2.8e-23 82.5 1.5 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGG42357.1 - 1.1e-11 45.2 0.5 1.3e-11 44.9 0.5 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SMC_hinge PF06470.13 EGG42357.1 - 0.09 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain MarB PF13999.6 EGG42357.1 - 0.12 12.2 0.3 0.32 10.9 0.1 1.8 2 1 0 2 2 2 0 MarB protein CwfJ_C_1 PF04677.15 EGG42357.1 - 0.13 12.1 0.9 0.21 11.5 0.9 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 ATP_synt_H PF05493.13 EGG42358.1 - 0.039 14.4 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit H P3A PF08727.11 EGG42358.1 - 0.085 12.2 0.2 0.18 11.2 0.2 1.6 1 1 0 1 1 1 0 Poliovirus 3A protein like zinc_ribbon_13 PF09855.9 EGG42359.1 - 0.011 15.9 1.6 0.027 14.6 1.6 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Lar_restr_allev PF14354.6 EGG42359.1 - 0.02 15.3 0.1 0.023 15.1 0.1 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF2225 PF09986.9 EGG42359.1 - 0.023 14.4 1.3 0.054 13.2 1.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TF_Zn_Ribbon PF08271.12 EGG42359.1 - 0.063 12.8 0.3 7.5 6.2 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 EGG42359.1 - 0.14 12.2 1.1 1.8 8.6 0.2 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ILVD_EDD PF00920.21 EGG42360.1 - 1.7e-208 693.5 4.3 1.9e-208 693.3 4.3 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_S24e PF01282.19 EGG42360.1 - 0.022 14.7 0.2 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S24e FpoO PF10621.9 EGG42361.1 - 0.4 11.0 3.9 1.2 9.5 3.9 1.7 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF3644 PF12358.8 EGG42363.1 - 0.06 13.8 3.1 0.15 12.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) Helicase_C_2 PF13307.6 EGG42364.1 - 6.4e-21 75.3 0.2 2.3e-20 73.5 0.0 2.0 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGG42364.1 - 5.5e-05 22.9 1.6 8e-05 22.3 0.1 2.0 3 0 0 3 3 3 1 DEAD_2 GIY-YIG PF01541.24 EGG42365.1 - 7.9e-06 26.1 0.2 1e-05 25.7 0.2 1.3 1 1 0 1 1 1 1 GIY-YIG catalytic domain PP_kinase_C PF13090.6 EGG42365.1 - 0.027 13.9 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Endonuc-HincII PF09226.11 EGG42365.1 - 0.054 12.8 0.1 0.061 12.6 0.1 1.0 1 0 0 1 1 1 0 Restriction endonuclease HincII zinc_ribbon_4 PF13717.6 EGG42370.1 - 0.046 13.7 0.9 0.7 9.9 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-AN1 PF01428.16 EGG42370.1 - 0.94 9.7 7.0 9.2 6.5 2.2 2.6 2 1 0 2 2 2 0 AN1-like Zinc finger YdjO PF14169.6 EGG42371.1 - 0.016 14.9 7.5 0.041 13.6 1.2 2.2 1 1 1 2 2 2 0 Cold-inducible protein YdjO TackOD1 PF18551.1 EGG42371.1 - 0.024 14.3 7.6 0.025 14.2 7.6 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-RING_4 PF14570.6 EGG42371.1 - 0.036 13.9 5.7 0.21 11.4 1.8 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGG42371.1 - 0.079 12.8 5.8 1 9.3 1.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf_UBZ PF18439.1 EGG42371.1 - 0.14 11.8 3.5 1.3 8.7 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger YacG PF03884.14 EGG42371.1 - 0.15 11.8 6.0 1.8 8.3 1.4 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Rad50_zn_hook PF04423.14 EGG42371.1 - 0.21 11.5 7.3 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 EGG42371.1 - 0.29 11.0 5.3 2.2 8.2 1.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) OrfB_Zn_ribbon PF07282.11 EGG42371.1 - 0.3 11.0 6.6 0.31 11.0 0.6 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Sgf11 PF08209.11 EGG42371.1 - 0.52 9.9 4.9 0.6 9.7 0.1 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.12 EGG42371.1 - 0.55 10.3 8.8 0.99 9.4 8.8 1.5 1 1 0 1 1 1 0 zinc-ribbons zf-TFIIB PF13453.6 EGG42371.1 - 0.89 8.9 10.5 2.2 7.7 1.0 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger Spt4 PF06093.13 EGG42371.1 - 1.1 9.4 8.7 1.3 9.2 3.7 2.1 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger PriA_CRR PF18319.1 EGG42371.1 - 1.2 9.2 8.9 4.1 7.5 0.9 2.2 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain zf-ribbon_3 PF13248.6 EGG42371.1 - 4.7 6.8 10.6 0.41 10.1 0.4 2.5 3 0 0 3 3 3 0 zinc-ribbon domain DUF872 PF05915.12 EGG42379.1 - 0.011 15.9 3.0 0.016 15.3 2.9 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) TssN PF17555.2 EGG42379.1 - 0.014 14.8 2.0 0.015 14.7 2.0 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF373 PF04123.13 EGG42379.1 - 0.016 14.7 0.7 0.016 14.7 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Phage_holin_5_2 PF16079.5 EGG42379.1 - 0.018 15.4 0.3 0.021 15.2 0.3 1.1 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V DUF1129 PF06570.11 EGG42379.1 - 0.027 13.9 1.6 0.031 13.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) YtpI PF14007.6 EGG42379.1 - 0.22 11.7 3.7 0.37 11.0 1.5 2.0 1 1 1 2 2 2 0 YtpI-like protein zinc_ribbon_15 PF17032.5 EGG42380.1 - 0.0058 17.4 0.2 0.0075 17.0 0.2 1.2 1 0 0 1 1 1 1 zinc-ribbon family zf-LITAF-like PF10601.9 EGG42380.1 - 0.0068 16.7 0.5 0.65 10.3 0.0 2.2 2 0 0 2 2 2 2 LITAF-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 EGG42380.1 - 0.03 13.8 3.3 0.4 10.2 3.3 2.2 1 1 0 1 1 1 0 TFIIB zinc-binding Nitroreductase PF00881.24 EGG42381.1 - 4.3e-24 85.5 0.2 1.3e-12 48.1 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 EGG42381.1 - 3.1e-10 40.0 0.7 8.6e-05 22.2 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase DUF1157 PF06636.11 EGG42381.1 - 0.063 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) PAC2 PF09754.9 EGG42383.1 - 6.3e-26 91.7 0.0 7.1e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 PAC2 family LpxI_N PF17930.1 EGG42383.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain PDDEXK_1 PF12705.7 EGG42384.1 - 3.3e-07 30.5 0.0 5e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 EGG42384.1 - 0.01 15.1 0.2 1.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2800) Cas_Cas4 PF01930.17 EGG42384.1 - 0.024 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 L_protein_N PF15518.6 EGG42384.1 - 0.083 12.7 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 L protein N-terminus Hint PF01079.20 EGG42385.1 - 0.02 14.4 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Hint module DUF4956 PF16316.5 EGG42385.1 - 0.085 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Aldo_ket_red PF00248.21 EGG42387.1 - 1.6e-57 195.0 0.0 1.8e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TF_Zn_Ribbon PF08271.12 EGG42388.1 - 0.14 11.7 3.8 1.8 8.2 3.8 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_6 PF14599.6 EGG42388.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.1 1 1 1 2 2 2 0 Zinc-ribbon PMT_2 PF13231.6 EGG42389.1 - 1.1e-07 32.2 19.4 1.1e-07 32.2 19.4 3.4 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SLATT_fungal PF18142.1 EGG42389.1 - 0.2 11.7 0.5 0.43 10.6 0.5 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DUF3681 PF12442.8 EGG42389.1 - 3.6 8.1 8.3 0.81 10.2 0.5 3.3 2 1 1 4 4 4 0 Protein of unknown function (DUF3681) Glycos_transf_2 PF00535.26 EGG42390.1 - 3.8e-34 117.9 0.0 8.7e-34 116.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 GtrA PF04138.14 EGG42390.1 - 2.8e-24 85.6 11.4 4.6e-23 81.7 12.3 2.2 1 1 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.6 EGG42390.1 - 2.1e-10 40.9 0.0 3.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGG42390.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 NTP_transf_3 PF12804.7 EGG42390.1 - 0.032 14.6 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Glyco_tranf_2_2 PF10111.9 EGG42390.1 - 0.038 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 RecR PF02132.15 EGG42392.1 - 0.0098 15.4 3.1 0.012 15.1 3.1 1.2 1 0 0 1 1 1 1 RecR protein FeoB_associated PF12669.7 EGG42392.1 - 0.56 10.7 10.7 1.1 9.7 10.7 1.6 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Chorismate_bind PF00425.18 EGG42394.1 - 1.1e-92 310.2 0.0 5.1e-92 308.1 0.0 2.0 2 1 1 3 3 3 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EGG42394.1 - 1e-21 77.7 0.5 6.8e-19 68.5 0.1 3.0 2 1 1 3 3 3 2 Anthranilate synthase component I, N terminal region FlbD PF06289.11 EGG42394.1 - 0.11 12.1 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins GATase PF00117.28 EGG42395.1 - 1.5e-52 178.2 0.0 1.6e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG42395.1 - 4.6e-09 36.3 0.3 1.5e-08 34.6 0.3 1.7 1 1 0 1 1 1 1 Peptidase C26 Glycos_transf_3 PF00591.21 EGG42396.1 - 2.9e-78 263.0 1.0 4.1e-78 262.5 1.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EGG42396.1 - 3.1e-09 36.5 0.2 7.3e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain AvrM-A PF18241.1 EGG42396.1 - 0.49 10.8 3.2 0.27 11.7 0.3 1.9 2 0 0 2 2 2 0 Flax-rust effector AvrM-A IGPS PF00218.21 EGG42397.1 - 8.9e-71 238.0 1.2 1e-70 237.8 1.2 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 EGG42397.1 - 2.5e-06 27.4 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 EGG42397.1 - 0.00024 20.3 0.1 0.00063 19.0 0.1 1.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 EGG42397.1 - 0.0051 15.9 0.0 0.094 11.7 0.0 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Cellulase PF00150.18 EGG42397.1 - 0.016 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) His_biosynth PF00977.21 EGG42397.1 - 0.031 13.7 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 EGG42397.1 - 0.076 12.2 1.1 2 7.6 0.0 2.4 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase AP_endonuc_2 PF01261.24 EGG42397.1 - 0.079 12.4 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel PALP PF00291.25 EGG42398.1 - 6.4e-45 153.8 1.0 7.6e-45 153.6 1.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Succ_CoA_lig PF13607.6 EGG42398.1 - 0.062 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Trp_syntA PF00290.20 EGG42399.1 - 2.4e-82 275.7 1.4 2.6e-82 275.5 1.4 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 EGG42399.1 - 2.9e-08 33.5 0.2 1.1e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.21 EGG42399.1 - 1.9e-07 30.6 0.8 2.6e-07 30.1 0.8 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 EGG42399.1 - 3.3e-05 23.2 0.5 0.00047 19.4 0.1 2.7 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 EGG42399.1 - 4.2e-05 22.7 0.1 0.00019 20.6 0.1 2.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.17 EGG42399.1 - 5e-05 22.9 2.0 0.0004 19.9 2.0 2.2 1 1 0 1 1 1 1 PcrB family IMPDH PF00478.25 EGG42399.1 - 0.00051 19.1 0.6 0.0024 16.9 0.2 2.1 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EGG42399.1 - 0.0023 17.3 0.2 0.0046 16.3 0.0 1.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IGPS PF00218.21 EGG42399.1 - 0.008 15.4 0.0 0.042 13.0 0.0 2.0 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 EGG42399.1 - 0.01 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.17 EGG42399.1 - 0.016 14.5 0.5 0.051 12.9 0.5 2.0 1 1 0 1 1 1 0 Thiamine monophosphate synthase TGT PF01702.18 EGG42399.1 - 0.034 13.3 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase Ribul_P_3_epim PF00834.19 EGG42399.1 - 0.076 12.4 0.2 0.12 11.8 0.2 1.5 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF3892 PF13031.6 EGG42399.1 - 0.34 11.5 2.8 0.35 11.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3892) zf-C2H2_4 PF13894.6 EGG42400.1 - 0.0014 19.3 11.8 0.074 13.9 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGG42400.1 - 0.003 17.9 13.8 0.16 12.4 3.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 EGG42400.1 - 0.007 16.6 2.1 0.047 14.0 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon zf-C2H2_3rep PF18868.1 EGG42400.1 - 0.0091 16.7 7.5 0.019 15.7 7.5 1.5 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Prok-RING_1 PF14446.6 EGG42400.1 - 0.011 15.7 4.7 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-H2C2_2 PF13465.6 EGG42400.1 - 0.013 15.9 5.3 0.013 15.9 5.3 2.8 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 EGG42400.1 - 0.021 15.2 4.5 0.021 15.2 4.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGG42400.1 - 0.042 14.1 16.3 0.52 10.7 4.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 EGG42400.1 - 0.074 13.8 4.0 0.074 13.8 2.9 1.5 1 1 1 2 2 2 0 zinc-ribbon family zf-CHCC PF10276.9 EGG42400.1 - 0.1 12.7 1.4 2.9 8.0 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger domain DNA_RNApol_7kD PF03604.13 EGG42400.1 - 0.13 11.9 2.0 0.96 9.2 0.2 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-CSL PF05207.13 EGG42400.1 - 0.14 11.9 1.8 0.28 10.9 1.2 1.7 1 1 1 2 2 2 0 CSL zinc finger zf-HYPF PF07503.12 EGG42400.1 - 0.16 11.7 4.9 0.36 10.6 1.1 2.4 2 0 0 2 2 2 0 HypF finger Ribosomal_S27e PF01667.17 EGG42400.1 - 0.23 11.2 3.6 0.61 9.8 3.6 1.7 1 1 0 1 1 1 0 Ribosomal protein S27 DUF629 PF04780.12 EGG42400.1 - 0.26 9.7 17.7 0.38 9.2 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-BED PF02892.15 EGG42400.1 - 0.43 10.6 9.3 2.4 8.3 2.6 2.4 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 EGG42400.1 - 3.1 8.0 5.5 4.3 7.5 0.9 2.1 1 1 1 2 2 2 0 Zinc ribbon domain CTP_synth_N PF06418.14 EGG42401.1 - 2e-110 368.3 0.2 2.8e-110 367.8 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGG42401.1 - 1.1e-54 185.1 0.0 1.8e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG42401.1 - 8.3e-13 48.6 0.0 2.5e-11 43.8 0.0 2.3 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.23 EGG42401.1 - 0.034 14.2 0.0 0.094 12.8 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 EGG42401.1 - 0.039 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family AAA_31 PF13614.6 EGG42401.1 - 0.13 12.2 0.2 0.65 9.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain NAD_kinase PF01513.21 EGG42402.1 - 2.5e-30 105.7 0.3 4.6e-30 104.8 0.2 1.4 2 0 0 2 2 2 1 ATP-NAD kinase HTH_24 PF13412.6 EGG42402.1 - 4.6e-05 22.9 0.6 0.00021 20.8 0.0 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EGG42402.1 - 8.1e-05 22.4 1.4 0.0051 16.7 0.3 2.8 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EGG42402.1 - 0.00021 21.2 1.7 0.00034 20.5 0.1 2.2 3 0 0 3 3 3 1 MarR family RNA_pol_Rpc34 PF05158.12 EGG42402.1 - 0.00023 20.7 0.9 0.00033 20.1 0.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 EGG42402.1 - 0.0015 18.4 0.1 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EGG42402.1 - 0.018 15.6 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain TPALS PF18178.1 EGG42402.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family PfkB PF00294.24 EGG42403.1 - 1.2e-10 41.2 0.0 8.6e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase TrmB PF01978.19 EGG42404.1 - 2.3e-06 27.4 0.1 2.6e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EGG42404.1 - 2.3e-05 23.9 1.1 3.3e-05 23.4 1.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EGG42404.1 - 9.1e-05 22.4 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EGG42404.1 - 0.00022 20.9 0.0 0.0003 20.5 0.0 1.3 1 1 0 1 1 1 1 IclR helix-turn-helix domain DUF1492 PF07374.11 EGG42404.1 - 0.00037 20.6 0.1 0.00044 20.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) HTH_5 PF01022.20 EGG42404.1 - 0.00041 20.1 0.5 0.00048 19.9 0.5 1.1 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EGG42404.1 - 0.0019 18.1 1.4 0.0026 17.7 1.4 1.3 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 EGG42404.1 - 0.0027 17.5 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 EGG42404.1 - 0.0049 16.7 0.0 0.0054 16.6 0.0 1.1 1 0 0 1 1 1 1 MarR family Mga PF05043.13 EGG42404.1 - 0.0061 17.1 0.2 0.0065 17.0 0.2 1.1 1 0 0 1 1 1 1 Mga helix-turn-helix domain Sigma70_r4 PF04545.16 EGG42404.1 - 0.0098 15.4 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 FUR PF01475.19 EGG42404.1 - 0.023 14.8 0.1 0.026 14.7 0.1 1.2 1 1 0 1 1 1 0 Ferric uptake regulator family HTH_8 PF02954.19 EGG42404.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Rrf2 PF02082.20 EGG42404.1 - 0.073 13.4 0.3 0.087 13.2 0.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator MerC PF03203.14 EGG42405.1 - 0.0037 17.7 1.7 0.0049 17.3 1.7 1.0 1 0 0 1 1 1 1 MerC mercury resistance protein DUF3290 PF11694.8 EGG42405.1 - 0.25 11.3 1.6 0.17 11.8 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) SPW PF03779.14 EGG42405.1 - 5.3 6.7 7.4 0.78 9.4 0.2 2.5 3 0 0 3 3 3 0 SPW repeat Ribosomal_S26e PF01283.19 EGG42408.1 - 7.1e-23 81.1 0.7 8.6e-23 80.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e CxC5 PF18718.1 EGG42408.1 - 0.0059 16.7 0.5 0.0071 16.4 0.5 1.1 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases zinc_ribbon_11 PF11682.8 EGG42408.1 - 0.018 15.1 3.3 1.8 8.6 0.1 2.1 1 1 1 2 2 2 0 Probable zinc-ribbon zf-dskA_traR PF01258.17 EGG42408.1 - 0.047 13.6 1.0 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger CDP-OH_P_transf PF01066.21 EGG42409.1 - 3.2e-11 43.8 0.5 3.2e-11 43.8 0.5 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Arginase PF00491.21 EGG42410.1 - 1.1e-67 228.5 0.0 1.4e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family tRNA-Thr_ED PF08915.11 EGG42411.1 - 4.2e-44 149.9 0.3 7.2e-44 149.2 0.3 1.4 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.20 EGG42411.1 - 1.2e-23 83.0 0.3 2.6e-23 82.0 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGG42411.1 - 1.4e-15 57.8 0.2 3e-15 56.7 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2061 PF09834.9 EGG42412.1 - 3e-09 37.2 7.0 3.7e-09 36.9 7.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2061) Rhodanese PF00581.20 EGG42415.1 - 5.8e-08 33.2 0.1 1.1e-07 32.3 0.1 1.5 1 1 0 1 1 1 1 Rhodanese-like domain TrkH PF02386.16 EGG42416.1 - 1.4e-25 89.7 28.9 2.5e-17 62.5 15.9 2.6 1 1 1 2 2 2 2 Cation transport protein CBS PF00571.28 EGG42416.1 - 1.1e-13 51.4 4.5 2e-06 28.1 0.4 2.6 2 0 0 2 2 2 2 CBS domain zf-C2H2 PF00096.26 EGG42417.1 - 0.00095 19.5 0.5 0.0022 18.4 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGG42417.1 - 0.0013 19.1 0.4 0.0013 19.0 0.4 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGG42417.1 - 0.0043 17.8 0.3 0.0086 16.8 0.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger DUF3222 PF11519.8 EGG42417.1 - 0.012 15.8 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) zf-C2H2_9 PF16293.5 EGG42417.1 - 0.024 14.5 0.3 0.031 14.1 0.3 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) CTU2 PF10288.9 EGG42417.1 - 0.034 14.4 0.3 0.038 14.2 0.3 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF5528 PF17666.1 EGG42417.1 - 0.056 13.4 0.8 0.064 13.2 0.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5528) HTH_45 PF14947.6 EGG42418.1 - 4.7e-06 26.5 0.6 4.7e-06 26.5 0.6 1.4 2 0 0 2 2 2 1 Winged helix-turn-helix MarR PF01047.22 EGG42418.1 - 2.3e-05 24.2 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 EGG42418.1 - 0.024 14.8 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.14 EGG42418.1 - 0.072 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4389 PF14333.6 EGG42419.1 - 0.15 12.0 0.2 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF2976 PF11190.8 EGG42419.1 - 0.24 11.2 5.0 1.5 8.7 5.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) Jas PF16135.5 EGG42420.1 - 0.088 13.0 3.8 0.12 12.6 3.8 1.2 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling zf-LSD1 PF06943.12 EGG42420.1 - 0.43 10.5 8.8 0.31 10.9 1.6 2.4 2 0 0 2 2 2 0 LSD1 zinc finger Prok-JAB PF14464.6 EGG42422.1 - 4.4e-12 45.8 0.0 5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RadC PF04002.15 EGG42422.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain Guanylate_cyc PF00211.20 EGG42423.1 - 2.3e-16 60.0 0.1 2.9e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DS PF01916.17 EGG42424.1 - 1.2e-77 261.0 0.1 1.5e-77 260.7 0.1 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Ribosomal_S25 PF03297.15 EGG42426.1 - 3.4e-10 40.0 4.7 4.4e-10 39.7 4.7 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DDRGK PF09756.9 EGG42426.1 - 0.0086 15.7 2.8 0.024 14.2 2.8 1.6 1 1 0 1 1 1 1 DDRGK domain DUF977 PF06163.11 EGG42426.1 - 0.0098 15.8 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) TrmB PF01978.19 EGG42426.1 - 0.024 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EGG42426.1 - 0.045 13.3 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EGG42426.1 - 0.06 13.2 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 MarR family Cyclophil_like PF04126.13 EGG42427.1 - 1.7e-07 31.1 0.0 2.5e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 EGG42427.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin-like family RNA_pol_Rpb6 PF01192.22 EGG42428.1 - 2e-11 43.6 0.4 4.4e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 Med9 PF07544.13 EGG42428.1 - 0.015 15.4 0.5 0.034 14.2 0.5 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF5344 PF17279.2 EGG42428.1 - 0.038 14.6 0.5 0.067 13.8 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Unstab_antitox PF09720.10 EGG42428.1 - 0.42 10.7 4.6 0.23 11.5 1.1 2.4 3 0 0 3 3 3 0 Putative addiction module component Alba PF01918.21 EGG42429.1 - 1.9e-09 37.2 0.4 2.8e-09 36.7 0.4 1.3 1 0 0 1 1 1 1 Alba Ribosomal_L2 PF00181.23 EGG42429.1 - 0.049 13.6 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain HTH_3 PF01381.22 EGG42430.1 - 7.3e-05 22.7 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 EGG42430.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 EGG42430.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 HTH domain YdaS_antitoxin PF15943.5 EGG42430.1 - 0.17 11.8 0.0 0.57 10.1 0.0 2.0 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Rpr2 PF04032.16 EGG42430.1 - 0.17 12.2 0.9 0.34 11.2 0.9 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Asn_synthase PF00733.21 EGG42431.1 - 1.8e-35 123.3 0.0 1.8e-19 70.6 0.0 2.0 1 1 1 2 2 2 2 Asparagine synthase QueC PF06508.13 EGG42431.1 - 3.4e-05 23.5 0.6 0.00026 20.5 0.1 2.5 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 EGG42431.1 - 5.6e-05 22.4 0.1 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 EGG42431.1 - 0.00025 20.8 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.14 EGG42431.1 - 0.0028 17.3 0.0 0.0064 16.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EGG42431.1 - 0.0035 16.2 0.0 0.011 14.6 0.0 1.8 2 1 0 2 2 2 1 tRNA methyl transferase zinc_ribbon_2 PF13240.6 EGG42431.1 - 0.041 13.6 2.5 4.2 7.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain RecR PF02132.15 EGG42431.1 - 0.061 12.9 0.7 0.061 12.9 0.7 2.3 2 0 0 2 2 2 0 RecR protein DZR PF12773.7 EGG42431.1 - 0.33 11.0 2.9 0.52 10.4 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EGG42431.1 - 5.4 6.6 6.5 1.1 8.8 1.9 2.2 2 1 0 2 2 2 0 zinc-ribbon domain Aldo_ket_red PF00248.21 EGG42433.1 - 4.5e-25 88.4 0.1 8.8e-20 71.1 0.2 2.4 1 1 1 2 2 2 2 Aldo/keto reductase family Arc_PepC PF06819.11 EGG42433.1 - 0.023 14.8 1.0 0.046 13.9 0.1 1.9 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain DUF321 PF03778.13 EGG42433.1 - 0.29 10.8 3.2 0.22 11.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF321) UbiA PF01040.18 EGG42434.1 - 7.1e-27 94.3 12.5 7.1e-27 94.3 12.5 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Tom6 PF17112.5 EGG42434.1 - 0.4 10.2 3.8 0.41 10.2 0.3 2.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal DUF3488 PF11992.8 EGG42434.1 - 3.4 6.5 9.0 0.085 11.8 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Big_1 PF02369.16 EGG42435.1 - 1.7e-05 24.7 3.3 1.7e-05 24.7 3.3 3.2 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 EGG42435.1 - 0.0037 17.5 0.9 0.024 14.9 0.3 2.8 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Invasin_D3 PF09134.10 EGG42435.1 - 0.0086 16.4 23.4 0.0086 16.4 1.0 5.5 6 1 0 6 6 6 2 Invasin, domain 3 Rhabdo_glycop PF00974.18 EGG42435.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Big_3 PF07523.12 EGG42435.1 - 0.026 14.8 0.2 0.18 12.2 0.2 2.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Spore_YhaL PF14147.6 EGG42435.1 - 0.24 11.1 0.6 0.51 10.1 0.6 1.6 1 0 0 1 1 1 0 Sporulation protein YhaL Pilin_N PF07790.11 EGG42436.1 - 0.0011 19.8 1.8 0.0011 19.8 1.8 2.2 2 2 0 2 2 2 1 Archaeal Type IV pilin, N-terminal DUF4926 PF16277.5 EGG42436.1 - 0.39 10.1 1.7 4.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4926) NPCBM_assoc PF10633.9 EGG42437.1 - 0.00043 20.5 7.1 0.061 13.6 0.6 4.4 5 0 0 5 5 5 2 NPCBM-associated, NEW3 domain of alpha-galactosidase Pilin_N PF07790.11 EGG42438.1 - 0.016 16.1 0.6 0.038 14.9 0.0 2.0 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal RTT107_BRCT_6 PF16771.5 EGG42439.1 - 0.033 14.4 0.1 0.047 13.9 0.1 1.2 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain TackOD1 PF18551.1 EGG42440.1 - 5.2e-29 101.2 6.4 7.7e-29 100.7 6.4 1.2 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 Zn-ribbon_8 PF09723.10 EGG42440.1 - 0.0052 16.9 13.4 2.2 8.5 0.1 4.3 3 1 0 3 3 3 2 Zinc ribbon domain zf-ribbon_3 PF13248.6 EGG42440.1 - 0.059 12.8 0.8 1.7 8.1 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 EGG42440.1 - 0.073 12.8 5.1 3 7.7 1.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_KTR PF14205.6 EGG42440.1 - 0.12 12.2 3.6 0.34 10.8 0.2 2.9 2 0 0 2 2 2 0 Cysteine-rich KTR YdjO PF14169.6 EGG42440.1 - 0.16 11.7 2.9 0.92 9.3 0.3 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO HypA PF01155.19 EGG42440.1 - 0.4 10.7 8.1 53 3.9 3.0 3.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CxC7 PF18866.1 EGG42440.1 - 0.51 10.5 3.9 0.2 11.8 0.6 2.1 2 1 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases zinc-ribbons_6 PF07191.12 EGG42440.1 - 0.55 10.3 10.6 1.6 8.8 4.1 2.5 1 1 2 3 3 3 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.12 EGG42440.1 - 0.61 10.1 4.8 7.4 6.6 0.0 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 EGG42440.1 - 1.4 9.0 6.7 3 7.9 1.3 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain FYVE PF01363.21 EGG42440.1 - 1.4 9.1 9.0 1.1 9.4 0.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger C1_4 PF07975.12 EGG42440.1 - 1.9 8.8 8.1 2.2 8.6 1.6 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 EGG42440.1 - 2.6 8.0 11.7 61 3.7 1.0 4.1 3 1 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EGG42440.1 - 4.5 7.4 8.3 66 3.7 8.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-TFIIB PF13453.6 EGG42440.1 - 5.4 6.4 6.7 20 4.6 0.5 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger T2SSE PF00437.20 EGG42441.1 - 1.6e-49 168.4 0.0 3.1e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGG42441.1 - 0.0057 16.0 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EGG42441.1 - 0.0077 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 EGG42441.1 - 0.0086 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGG42441.1 - 0.014 15.9 0.2 0.13 12.8 0.0 2.4 2 1 0 2 2 2 0 ABC transporter DEAD PF00270.29 EGG42441.1 - 0.082 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 EGG42441.1 - 0.19 12.1 0.1 0.51 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain T2SSF PF00482.23 EGG42442.1 - 1.7e-15 57.0 0.2 1.7e-15 57.0 0.2 2.4 4 0 0 4 4 4 1 Type II secretion system (T2SS), protein F Spore_III_AB PF09548.10 EGG42442.1 - 0.13 12.4 1.2 2.1 8.4 1.2 2.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF2207 PF09972.9 EGG42442.1 - 0.42 9.3 4.7 4.2 6.0 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) T2SSF PF00482.23 EGG42443.1 - 1.9e-17 63.4 0.3 1.9e-17 63.4 0.3 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F MtrG PF04210.13 EGG42443.1 - 0.0089 15.9 2.1 0.034 14.0 0.3 2.7 3 0 0 3 3 3 1 Tetrahydromethanopterin S-methyltransferase, subunit G Spore_III_AB PF09548.10 EGG42443.1 - 0.027 14.6 1.5 0.076 13.1 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF3671 PF12420.8 EGG42443.1 - 0.4 10.8 8.3 1.2 9.2 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function Rab5ip PF07019.12 EGG42443.1 - 9.4 6.9 11.8 36 5.0 0.1 3.5 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) TrmB PF01978.19 EGG42444.1 - 3.5e-14 52.4 0.1 7.8e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EGG42444.1 - 2.8e-05 23.9 0.0 5.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EGG42444.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 EGG42444.1 - 0.0027 17.6 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 MarR family RisS_PPD PF16524.5 EGG42444.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS HTH_11 PF08279.12 EGG42444.1 - 0.067 13.1 0.6 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 HTH domain DUF2203 PF09969.9 EGG42445.1 - 9.4e-36 123.2 0.1 1.1e-35 123.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) GCR1_C PF12550.8 EGG42445.1 - 0.088 13.1 1.1 0.13 12.6 0.1 1.8 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes DUF2407_C PF13373.6 EGG42446.1 - 0.029 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain Putative_PNPOx PF01243.20 EGG42447.1 - 6.2e-12 45.5 0.0 7.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EGG42447.1 - 3.2e-06 27.2 0.0 3.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 EGG42447.1 - 0.053 13.3 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Rotamase_3 PF13616.6 EGG42448.1 - 8.9e-26 90.7 0.2 1.5e-25 90.0 0.2 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGG42448.1 - 5.2e-23 81.8 0.1 6.2e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGG42448.1 - 1.7e-07 32.1 0.0 2e-07 31.8 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain NTPase_I-T PF01931.18 EGG42448.1 - 0.0041 16.9 0.0 0.0054 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF84 PapD_C PF02753.17 EGG42448.1 - 0.036 14.4 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain RTX PF02382.15 EGG42449.1 - 0.00079 19.2 1.1 0.00091 19.0 1.1 1.0 1 0 0 1 1 1 1 N-terminal domain in RTX protein AF0941-like PF14591.6 EGG42449.1 - 0.026 15.1 2.5 0.035 14.7 2.5 1.2 1 0 0 1 1 1 0 AF0941-like DUF5547 PF17701.1 EGG42449.1 - 0.06 13.2 0.3 0.63 9.9 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5547) LysM PF01476.20 EGG42449.1 - 0.084 13.0 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 LysM domain RecG_N PF17190.4 EGG42449.1 - 0.1 13.3 2.3 0.52 11.1 0.2 2.0 1 1 1 2 2 2 0 RecG N-terminal helical domain Helicase_C PF00271.31 EGG42450.1 - 6.4e-24 84.4 0.1 2e-23 82.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG42450.1 - 9e-20 71.4 0.0 2.7e-19 69.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG42450.1 - 5.9e-18 65.2 0.1 3.3e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EGG42450.1 - 0.0034 17.3 0.0 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain Helicase_C_2 PF13307.6 EGG42450.1 - 0.03 14.5 0.0 0.7 10.0 0.0 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain DUF3638 PF12340.8 EGG42450.1 - 0.067 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) DUF2007 PF09413.10 EGG42450.1 - 0.13 12.5 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein TrmB PF01978.19 EGG42451.1 - 3.7e-15 55.6 0.0 2.1e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EGG42451.1 - 0.00032 20.6 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EGG42451.1 - 0.00046 20.0 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 EGG42451.1 - 0.0015 18.5 0.1 0.0044 16.9 0.0 1.9 2 0 0 2 2 2 1 HTH domain Fe_dep_repress PF01325.19 EGG42451.1 - 0.0017 18.5 0.0 0.0082 16.3 0.0 2.2 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EGG42451.1 - 0.0039 16.7 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding FtsK_gamma PF09397.10 EGG42451.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Ftsk gamma domain HTH_IclR PF09339.10 EGG42451.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Pedibin PF08182.11 EGG42451.1 - 0.13 12.1 1.3 0.26 11.1 1.3 1.5 1 0 0 1 1 1 0 Pedibin/Hym-346 family MFS_1 PF07690.16 EGG42452.1 - 1.7e-27 96.3 64.8 2.1e-21 76.2 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGG42452.1 - 7.5e-07 28.3 29.8 1.5e-06 27.4 29.8 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 EGG42452.1 - 0.0034 16.0 4.2 0.0034 16.0 4.2 3.8 2 2 1 3 3 3 1 MFS/sugar transport protein MFS_3 PF05977.13 EGG42452.1 - 0.011 14.2 6.9 0.15 10.4 1.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector MG2 PF01835.19 EGG42453.1 - 0.0001 22.7 0.1 0.28 11.7 0.0 2.3 2 0 0 2 2 2 2 MG2 domain FlgD_ig PF13860.6 EGG42453.1 - 0.0014 18.5 0.9 0.045 13.6 0.1 2.5 2 0 0 2 2 2 1 FlgD Ig-like domain PsbH PF00737.20 EGG42453.1 - 0.062 13.0 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein VIT1 PF01988.19 EGG42454.1 - 6.3e-53 179.8 1.8 7e-53 179.7 1.8 1.0 1 0 0 1 1 1 1 VIT family TM_helix PF05552.12 EGG42455.1 - 5.6e-12 45.5 11.2 7.8e-07 29.0 0.2 3.1 3 0 0 3 3 3 2 Conserved TM helix MS_channel PF00924.18 EGG42455.1 - 5.1e-07 29.4 7.9 5.1e-07 29.4 7.9 3.0 3 1 0 3 3 3 1 Mechanosensitive ion channel DUF502 PF04367.13 EGG42455.1 - 0.44 10.5 4.5 7.7 6.5 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF502) DASH_Dam1 PF08653.10 EGG42456.1 - 0.45 10.3 3.5 17 5.3 0.2 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Tubulin PF00091.25 EGG42457.1 - 5.5e-19 69.1 0.0 1.2e-18 68.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Snf7 PF03357.21 EGG42458.1 - 1.8e-06 27.7 0.0 2.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Snf7 Proteasom_PSMB PF10508.9 EGG42458.1 - 7.2e-05 21.5 1.2 0.0001 21.0 1.2 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DASH_Dam1 PF08653.10 EGG42458.1 - 0.0021 17.8 1.8 7.9 6.4 0.2 3.9 2 1 2 4 4 4 2 DASH complex subunit Dam1 Phage_int_SAM_2 PF12834.7 EGG42458.1 - 0.096 13.4 1.1 1.1 10.0 0.4 2.3 1 1 1 2 2 2 0 Phage integrase, N-terminal dCMP_cyt_deam_1 PF00383.23 EGG42459.1 - 2.4e-26 91.5 1.3 3.3e-26 91.1 1.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG42459.1 - 2.7e-14 53.1 0.2 3.4e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 MafB19-like deaminase DNA_pol_B PF00136.21 EGG42460.1 - 4.9e-54 183.8 5.5 9e-54 182.9 5.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGG42460.1 - 3e-40 138.4 3.6 6.3e-40 137.3 3.6 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 EGG42460.1 - 5.9e-07 29.6 1.7 1.8e-06 28.1 1.7 1.7 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EGG42460.1 - 2.5e-05 24.1 1.6 0.00014 21.6 1.6 2.2 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB SpoVIF PF14069.6 EGG42460.1 - 0.041 13.7 0.0 0.2 11.4 0.0 2.2 1 0 0 1 1 1 0 Stage VI sporulation protein F CNP1 PF08750.11 EGG42460.1 - 0.16 11.9 0.3 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 CNP1-like family DUF3785 PF12653.7 EGG42460.1 - 0.57 10.3 5.4 3.5 7.7 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) MtN3_slv PF03083.16 EGG42461.1 - 5e-08 32.9 3.3 5.7e-08 32.7 3.3 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 EGG42461.1 - 0.00012 21.8 4.1 0.00012 21.8 4.1 1.5 2 0 0 2 2 2 1 PQ loop repeat DUF4389 PF14333.6 EGG42461.1 - 0.0084 16.0 3.1 0.88 9.5 0.9 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4389) DUF3784 PF12650.7 EGG42461.1 - 0.012 15.8 13.9 0.15 12.3 13.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) LAB_N PF07578.11 EGG42461.1 - 0.075 13.1 2.9 0.1 12.7 2.9 1.3 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Imp-YgjV PF10688.9 EGG42461.1 - 0.56 10.0 9.4 1 9.2 9.4 1.6 1 1 0 1 1 1 0 Bacterial inner membrane protein TIM PF00121.18 EGG42462.1 - 7.6e-10 38.6 4.6 2.3e-09 37.0 0.4 2.0 1 1 1 2 2 2 2 Triosephosphate isomerase ThiG PF05690.14 EGG42462.1 - 1.5e-05 24.4 0.2 2.3e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 EGG42462.1 - 0.00013 21.2 0.1 0.00025 20.2 0.1 1.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IGPS PF00218.21 EGG42462.1 - 0.02 14.1 0.1 0.034 13.3 0.1 1.5 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase YolD PF08863.10 EGG42463.1 - 0.049 13.7 3.6 5.9 7.0 1.0 2.5 2 1 0 2 2 2 0 YolD-like protein zf-CDGSH PF09360.10 EGG42464.1 - 2.4e-12 46.9 0.6 2.8e-12 46.6 0.6 1.2 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Glyoxalase PF00903.25 EGG42465.1 - 1.5e-06 28.5 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGG42465.1 - 2.8e-05 24.8 0.0 5.1e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain PEP-utilizers_C PF02896.18 EGG42466.1 - 1.7e-84 283.4 0.5 2.9e-84 282.6 0.5 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 EGG42466.1 - 1.2e-57 195.7 0.1 1.1e-42 146.4 0.0 3.6 2 1 1 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EGG42466.1 - 2.6e-26 91.1 0.2 6e-26 90.0 0.2 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain CBS PF00571.28 EGG42467.1 - 5.1e-15 55.7 0.2 2.6e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 CBS domain HTH_3 PF01381.22 EGG42467.1 - 7.7e-12 45.1 0.1 1.5e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EGG42467.1 - 7.1e-07 29.1 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EGG42467.1 - 1.2e-05 25.5 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EGG42467.1 - 0.044 13.6 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 EGG42467.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4 PF04545.16 EGG42467.1 - 0.17 11.4 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 EGG42467.1 - 0.2 11.7 0.1 0.51 10.4 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Glyoxalase_4 PF13669.6 EGG42469.1 - 1.2e-22 80.2 0.0 1.4e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EGG42469.1 - 9.5e-12 45.2 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGG42469.1 - 1.6e-10 41.4 0.0 1.8e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EGG42469.1 - 0.0039 18.0 0.0 0.0049 17.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain TPR_10 PF13374.6 EGG42469.1 - 0.024 14.5 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Hemerythrin PF01814.23 EGG42470.1 - 6e-11 43.1 0.2 1e-10 42.3 0.0 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Nuf2 PF03800.14 EGG42470.1 - 0.057 13.5 0.6 0.39 10.8 0.1 2.0 1 1 0 2 2 2 0 Nuf2 family APC1_C PF18122.1 EGG42470.1 - 0.061 13.3 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain MM_CoA_mutase PF01642.22 EGG42471.1 - 2.4e-212 706.0 0.2 2.8e-212 705.9 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase HigB_toxin PF09907.9 EGG42471.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system MeaB PF03308.16 EGG42472.1 - 1.4e-67 227.5 2.3 2e-67 227.0 2.3 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EGG42472.1 - 1.2e-05 25.0 0.1 1.2e-05 25.0 0.1 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EGG42472.1 - 2.9e-05 24.0 0.8 0.0077 16.0 0.1 2.5 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGG42472.1 - 5.2e-05 23.2 0.7 0.012 15.6 0.0 2.7 2 1 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 EGG42472.1 - 0.0018 17.6 2.8 0.0057 15.9 2.8 1.9 1 1 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 EGG42472.1 - 0.0063 16.9 0.1 0.011 16.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGG42472.1 - 0.0075 16.8 12.4 0.14 12.7 12.1 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG42472.1 - 0.013 16.0 1.3 0.041 14.4 0.2 2.2 2 0 0 2 2 2 0 ABC transporter MnmE_helical PF12631.7 EGG42472.1 - 0.014 15.6 0.6 0.021 15.0 0.5 1.4 1 1 0 1 1 1 0 MnmE helical domain RNA_helicase PF00910.22 EGG42472.1 - 0.017 15.5 0.7 2.5 8.5 0.0 3.3 3 1 0 3 3 3 0 RNA helicase AAA_22 PF13401.6 EGG42472.1 - 0.017 15.4 0.2 0.058 13.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGG42472.1 - 0.026 14.6 4.2 0.25 11.4 4.2 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EGG42472.1 - 0.028 14.1 0.5 0.047 13.4 0.5 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG42472.1 - 0.042 13.7 0.4 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 NTPase PRK PF00485.18 EGG42472.1 - 0.05 13.3 1.9 0.06 13.1 0.2 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EGG42472.1 - 0.082 12.7 0.3 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EGG42472.1 - 0.27 11.5 2.1 0.72 10.2 1.9 2.0 1 1 0 1 1 1 0 AAA domain Peptidase_M1 PF01433.20 EGG42474.1 - 4.8e-89 297.6 1.4 9e-89 296.7 1.4 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGG42474.1 - 1.1e-63 215.7 0.2 4.3e-63 213.7 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGG42474.1 - 6.6e-53 179.7 4.3 1.5e-52 178.5 4.3 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 EGG42474.1 - 0.0048 16.3 0.1 0.016 14.6 0.1 1.8 1 0 0 1 1 1 1 Putative aminopeptidase DUF3013 PF11217.8 EGG42474.1 - 0.053 13.4 0.8 0.29 11.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3013) B12-binding PF02310.19 EGG42475.1 - 2e-21 76.2 0.1 2.3e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 EGG42475.1 - 0.017 14.2 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Isochorismatase PF00857.20 EGG42475.1 - 0.043 14.0 0.1 25 5.0 0.1 2.9 1 1 1 3 3 3 0 Isochorismatase family Peptidase_M22 PF00814.25 EGG42475.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family IlvN PF07991.12 EGG42476.1 - 3e-67 225.3 0.4 4.1e-67 224.9 0.4 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGG42476.1 - 1.9e-57 193.6 1.9 2.8e-57 193.1 1.9 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 EGG42476.1 - 1.5e-06 27.7 0.1 2.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGG42476.1 - 1.6e-05 25.1 0.3 0.00016 21.8 0.1 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG42476.1 - 0.0001 22.8 0.1 0.00035 21.1 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 EGG42476.1 - 0.0053 16.8 0.2 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CTP_transf_like PF01467.26 EGG42477.1 - 9e-15 55.1 0.0 1.5e-14 54.4 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 EGG42477.1 - 2.9e-05 23.5 0.0 0.0016 17.7 0.0 2.4 2 1 1 3 3 3 1 HIGH Nucleotidyl Transferase Citrate_ly_lig PF08218.11 EGG42477.1 - 0.01 15.6 0.0 0.07 12.8 0.0 2.0 1 1 1 2 2 2 1 Citrate lyase ligase C-terminal domain MazG PF03819.17 EGG42477.1 - 0.064 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Pantoate_ligase PF02569.15 EGG42477.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.4 1 1 0 1 1 1 0 Pantoate-beta-alanine ligase CBS PF00571.28 EGG42478.1 - 3.5e-20 72.2 0.6 2.4e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 CBS domain GTP_EFTU_D2 PF03144.25 EGG42479.1 - 5.8e-10 39.4 0.2 1.8e-09 37.9 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF2004 PF09406.10 EGG42479.1 - 0.058 13.7 0.0 0.7 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) PHO4 PF01384.20 EGG42480.1 - 4.7e-91 305.3 39.9 2.2e-90 303.2 39.9 1.8 1 1 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 EGG42480.1 - 0.078 12.8 0.3 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF1656 PF07869.12 EGG42480.1 - 0.097 12.7 0.1 0.097 12.7 0.1 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1656) PhoU_div PF01865.16 EGG42481.1 - 1.1e-22 80.4 10.6 1.3e-22 80.2 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 ArAE_1_C PF11728.8 EGG42481.1 - 0.065 13.2 3.5 0.18 11.8 2.3 2.1 2 1 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain Med4 PF10018.9 EGG42481.1 - 0.3 10.7 3.8 0.28 10.9 1.4 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 7TM_GPCR_Srab PF10292.9 EGG42482.1 - 0.029 13.3 0.3 0.032 13.1 0.3 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DUF726 PF05277.12 EGG42483.1 - 0.003 16.6 0.0 0.0034 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 EGG42484.1 - 3.9e-07 29.8 0.1 5.1e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 EGG42484.1 - 0.00023 20.8 3.7 0.0035 16.9 3.7 2.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EGG42484.1 - 0.003 16.9 0.2 0.0058 15.9 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EGG42484.1 - 0.0035 16.9 0.5 0.0045 16.6 0.5 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase LCAT PF02450.15 EGG42484.1 - 0.0036 16.5 0.1 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 EGG42484.1 - 0.0048 16.0 0.1 0.0064 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Say1_Mug180 PF10340.9 EGG42484.1 - 0.0068 15.3 0.3 0.0089 14.9 0.3 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase VirJ PF06057.11 EGG42484.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cutinase PF01083.22 EGG42484.1 - 0.082 12.9 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_8 PF06259.12 EGG42484.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase tRNA-synt_1g PF09334.11 EGG42485.1 - 2.3e-137 457.9 2.0 3e-137 457.5 2.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGG42485.1 - 2e-16 59.4 2.0 5.6e-07 28.2 0.1 4.0 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EGG42485.1 - 6.3e-11 42.2 0.3 3.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGG42485.1 - 2.7e-07 29.9 0.1 0.0014 17.7 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 EGG42485.1 - 8.7e-07 29.0 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA FhuF PF06276.12 EGG42485.1 - 0.0038 17.6 0.0 0.0072 16.8 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter zf-Di19 PF05605.12 EGG42485.1 - 0.11 12.8 2.5 0.26 11.6 2.5 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PolC_DP2 PF03833.13 EGG42485.1 - 0.17 9.8 0.3 0.24 9.2 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CHY PF05495.12 EGG42485.1 - 1.1 9.7 4.2 2.2 8.8 4.2 1.5 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.7 EGG42485.1 - 5.7 7.0 8.2 9.3 6.4 3.8 1.9 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 EGG42485.1 - 9.5 5.8 8.5 1.1 8.8 2.6 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding AdoHcyase_NAD PF00670.21 EGG42486.1 - 2.5e-52 177.2 0.8 2.5e-52 177.2 0.8 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 EGG42486.1 - 1.4e-49 168.9 0.0 2.1e-24 86.2 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 EGG42486.1 - 1.5e-09 37.5 0.1 3.7e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGG42486.1 - 2.1e-06 27.4 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGG42486.1 - 0.002 18.3 0.0 0.0063 16.8 0.0 1.9 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EGG42486.1 - 0.0022 18.1 0.6 0.06 13.4 0.1 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EGG42486.1 - 0.008 15.5 2.2 0.052 12.8 2.2 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGG42486.1 - 0.014 15.3 1.6 0.035 14.0 0.3 2.3 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGG42486.1 - 0.035 13.4 0.5 0.27 10.5 0.5 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 EGG42486.1 - 0.061 12.9 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF364 PF04016.12 EGG42486.1 - 0.071 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Putative heavy-metal chelation Rieske PF00355.26 EGG42487.1 - 1.1e-14 54.1 0.0 1.3e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EGG42487.1 - 7.2e-13 48.4 0.0 8.3e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_synthase PF02540.17 EGG42488.1 - 5.1e-74 248.4 0.4 6.1e-74 248.2 0.4 1.0 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 EGG42488.1 - 0.0014 18.4 0.0 0.04 13.6 0.0 2.1 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.16 EGG42488.1 - 0.0037 16.1 0.0 0.093 11.5 0.0 2.3 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.20 EGG42488.1 - 0.0038 17.0 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 EGG42488.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 EGG42488.1 - 0.016 14.8 0.1 0.089 12.4 0.0 2.1 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) HTH_23 PF13384.6 EGG42488.1 - 0.081 12.7 0.0 4 7.4 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain tRNA-synt_1e PF01406.19 EGG42489.1 - 1.5e-125 418.5 2.1 1.5e-125 418.5 2.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGG42489.1 - 1.1e-13 50.7 2.4 1.5e-08 33.8 1.3 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EGG42489.1 - 2e-09 37.8 0.0 8.4e-09 35.8 0.0 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 EGG42489.1 - 9.5e-08 30.7 0.1 1.2e-05 23.8 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EGG42489.1 - 1.4e-06 27.5 0.2 0.03 13.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) DUF1539 PF07560.11 EGG42489.1 - 0.91 9.6 7.8 26 4.9 7.8 2.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) tRNA-synt_1c PF00749.21 EGG42489.1 - 1.1 8.0 11.2 0.34 9.8 3.6 3.4 3 1 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain DUF2975 PF11188.8 EGG42490.1 - 0.025 14.5 0.9 0.039 13.8 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Insulin_TMD PF17870.1 EGG42490.1 - 0.16 12.0 4.2 1.1 9.4 0.4 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MMR_HSR1_C PF08438.10 EGG42491.1 - 4.8e-32 110.9 0.1 1.3e-31 109.5 0.0 1.7 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGG42491.1 - 7.5e-19 67.9 0.0 6.4e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EGG42491.1 - 2.5e-07 30.7 0.0 4.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGG42491.1 - 5.7e-05 22.7 0.1 0.0025 17.4 0.1 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG42491.1 - 0.00068 19.7 0.1 0.099 12.7 0.0 2.9 2 1 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 EGG42491.1 - 0.028 14.0 0.8 9.4 5.7 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CoA_binding_2 PF13380.6 EGG42493.1 - 2.6e-37 127.8 0.0 3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EGG42493.1 - 5.2e-07 30.3 0.0 9.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_57 PF03065.15 EGG42493.1 - 0.027 13.7 0.0 0.059 12.5 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 Epimerase PF01370.21 EGG42494.1 - 1.8e-22 80.0 0.0 2.3e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG42494.1 - 7.5e-18 65.0 0.1 1.9e-17 63.7 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGG42494.1 - 1.4e-11 44.1 0.0 4.8e-05 22.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EGG42494.1 - 3.4e-11 42.7 0.3 1.1e-10 41.0 0.3 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG42494.1 - 1.8e-07 30.6 0.0 1e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG42494.1 - 4.8e-06 25.9 0.5 0.00072 18.8 0.5 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGG42494.1 - 9.9e-06 25.6 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGG42494.1 - 0.00015 21.4 0.0 0.0005 19.7 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family DUF1731 PF08338.11 EGG42494.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Sarcolipin PF05366.11 EGG42494.1 - 0.043 13.5 0.1 0.084 12.6 0.1 1.4 1 0 0 1 1 1 0 Sarcolipin DUF3798 PF12683.7 EGG42494.1 - 0.083 12.3 0.0 0.27 10.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3798) adh_short PF00106.25 EGG42494.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF4423 PF14394.6 EGG42495.1 - 5.9e-05 22.8 0.3 8.7e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_45 PF14947.6 EGG42495.1 - 0.001 19.0 0.2 0.0022 18.0 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix Rio2_N PF09202.11 EGG42495.1 - 0.0058 16.8 0.2 0.039 14.2 0.1 2.2 2 1 0 2 2 2 1 Rio2, N-terminal TFIIE_alpha PF02002.17 EGG42495.1 - 0.012 15.4 0.9 0.021 14.7 0.9 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit TrmB PF01978.19 EGG42495.1 - 0.015 15.2 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 EGG42495.1 - 0.016 15.4 0.2 0.029 14.6 0.2 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.7 EGG42495.1 - 0.06 13.2 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 MarR family DUF1676 PF07898.13 EGG42495.1 - 0.23 11.5 4.1 0.28 11.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) BPL_LplA_LipB PF03099.19 EGG42496.1 - 3.6e-18 65.8 0.1 3e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 EGG42496.1 - 1.9e-15 56.5 0.2 5.2e-15 55.1 0.2 1.8 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.17 EGG42496.1 - 5e-07 29.5 0.5 9.9e-07 28.6 0.5 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Sec15 PF04091.12 EGG42496.1 - 0.018 14.5 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like UPF0122 PF04297.14 EGG42496.1 - 0.042 14.1 1.4 0.074 13.3 0.1 2.1 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Meis_PKNOX_N PF16493.5 EGG42496.1 - 0.047 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Rrf2 PF02082.20 EGG42496.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator AATF-Che1 PF13339.6 EGG42497.1 - 0.0014 19.3 5.0 0.0018 19.0 5.0 1.1 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DUF948 PF06103.11 EGG42497.1 - 0.044 14.0 0.1 2 8.7 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 EGG42497.1 - 0.062 13.9 1.8 0.17 12.4 1.8 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CREPT PF16566.5 EGG42497.1 - 0.085 13.0 4.0 0.11 12.7 3.7 1.4 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Peptidase_M10 PF00413.24 EGG42498.1 - 8.2e-08 32.2 0.5 3.3e-07 30.3 0.5 2.0 1 1 0 1 1 1 1 Matrixin TPR_1 PF00515.28 EGG42498.1 - 1.1e-07 31.3 0.1 0.016 15.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42498.1 - 2.9e-07 30.1 0.0 0.043 14.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_M57 PF12388.8 EGG42498.1 - 3.9e-05 23.3 0.2 6.5e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.6 EGG42498.1 - 4.3e-05 23.8 0.1 6.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M54 PF07998.11 EGG42498.1 - 0.0011 19.0 0.7 0.0028 17.7 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M54 Coatomer_E PF04733.14 EGG42498.1 - 0.0052 16.2 0.1 0.0089 15.5 0.1 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit Reprolysin_3 PF13582.6 EGG42498.1 - 0.0074 16.8 0.6 0.018 15.5 0.6 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TPR_6 PF13174.6 EGG42498.1 - 0.026 15.1 0.1 1.6 9.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42498.1 - 0.027 15.0 0.0 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG42498.1 - 0.032 15.0 0.0 10 7.2 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Peptidase_M43 PF05572.13 EGG42498.1 - 0.072 13.0 0.1 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 EGG42498.1 - 0.073 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Fis1_TPR_C PF14853.6 EGG42498.1 - 0.087 12.9 0.0 36 4.5 0.0 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MCM6_C PF18263.1 EGG42498.1 - 0.097 12.9 1.4 0.22 11.7 1.4 1.6 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain TPR_8 PF13181.6 EGG42498.1 - 2.3 8.7 6.2 4.8 7.6 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TFIIB PF00382.19 EGG42499.1 - 1.6e-32 111.3 6.4 3.3e-16 59.1 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG42499.1 - 3.6e-11 42.4 1.4 6.2e-11 41.6 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EGG42499.1 - 7.5e-05 22.5 0.6 0.00047 19.9 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 EGG42499.1 - 0.0023 17.9 0.6 0.0062 16.5 0.6 1.7 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 Ribosomal_S27e PF01667.17 EGG42499.1 - 0.064 13.0 0.4 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 Zn_Tnp_IS1595 PF12760.7 EGG42499.1 - 0.07 13.1 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RB_B PF01857.20 EGG42499.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain OrfB_Zn_ribbon PF07282.11 EGG42499.1 - 0.11 12.5 0.9 0.26 11.2 0.9 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.11 EGG42499.1 - 1.6 8.5 4.2 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 EGG42499.1 - 3.9 7.3 6.3 17 5.3 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF1599 PF07659.11 EGG42500.1 - 0.086 13.3 0.4 0.14 12.6 0.4 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 Pribosyltran PF00156.27 EGG42501.1 - 4e-07 29.7 0.0 0.012 15.1 0.0 2.1 1 1 1 2 2 2 2 Phosphoribosyl transferase domain DUF956 PF06115.11 EGG42501.1 - 0.031 14.0 0.3 6.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF956) FF PF01846.19 EGG42501.1 - 0.1 12.8 0.2 12 6.2 0.1 2.4 2 0 0 2 2 2 0 FF domain PHA_synth_III_E PF09712.10 EGG42503.1 - 1.6e-12 47.2 0.1 1.9e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF4200 PF13863.6 EGG42503.1 - 0.0017 18.8 6.5 0.088 13.2 0.0 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) Bacillus_HBL PF05791.11 EGG42503.1 - 0.0097 15.7 4.5 0.51 10.1 0.2 2.3 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) Cnn_1N PF07989.11 EGG42503.1 - 0.011 15.8 4.0 0.62 10.3 3.2 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 GAT PF03127.14 EGG42503.1 - 0.026 14.8 3.6 0.77 10.1 0.3 2.9 2 1 1 3 3 3 0 GAT domain Seryl_tRNA_N PF02403.22 EGG42503.1 - 0.029 14.6 2.2 0.029 14.6 2.2 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.9 EGG42503.1 - 0.069 13.4 5.2 0.4 11.0 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein ApoLp-III PF07464.11 EGG42503.1 - 0.12 12.5 5.9 2.1 8.4 2.0 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Lge1 PF11488.8 EGG42503.1 - 0.21 11.8 8.1 0.4 10.9 1.5 2.9 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 IFP_35_N PF07334.13 EGG42503.1 - 0.39 10.8 12.5 0.16 12.1 5.1 2.7 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus COG2 PF06148.11 EGG42503.1 - 0.79 9.8 5.2 18 5.4 1.9 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Hydrolase_4 PF12146.8 EGG42504.1 - 1.6e-13 50.5 0.0 4.3e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG42504.1 - 2.2e-13 50.4 0.0 3.6e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PhaC_N PF07167.13 EGG42504.1 - 2.2e-12 47.0 0.1 4.3e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF3141 PF11339.8 EGG42504.1 - 1.5e-06 27.0 0.0 2.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) DLH PF01738.18 EGG42504.1 - 0.00033 20.3 0.0 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGG42504.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PHB_depo_C PF06850.11 EGG42504.1 - 0.014 14.9 0.0 0.095 12.1 0.0 2.2 1 1 1 2 2 2 0 PHB de-polymerase C-terminus RIH_assoc PF08454.11 EGG42505.1 - 0.0074 16.1 1.9 0.0095 15.8 1.5 1.4 1 1 0 1 1 1 1 RyR and IP3R Homology associated DUF4473 PF14747.6 EGG42505.1 - 0.88 10.2 5.9 0.9 10.1 1.7 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4473) MazE_antitoxin PF04014.18 EGG42506.1 - 0.00074 19.4 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin GAT PF03127.14 EGG42506.1 - 0.015 15.6 1.0 0.023 15.0 1.0 1.3 1 0 0 1 1 1 0 GAT domain AbrB-like PF14250.6 EGG42506.1 - 0.026 14.6 0.0 0.062 13.4 0.0 1.6 2 0 0 2 2 2 0 AbrB-like transcriptional regulator Abhydrolase_1 PF00561.20 EGG42507.1 - 5.4e-27 95.1 0.0 2.8e-21 76.3 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG42507.1 - 5.4e-20 72.9 0.0 8e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG42507.1 - 3.7e-16 59.1 0.0 1e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EGG42507.1 - 2.7e-06 27.3 0.0 0.22 11.3 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Ndr PF03096.14 EGG42507.1 - 9.5e-05 21.2 0.0 0.00013 20.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 EGG42507.1 - 9.6e-05 22.3 0.0 0.033 14.0 0.0 2.7 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.7 EGG42507.1 - 0.058 13.2 0.0 2.8 7.7 0.0 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family DUF3530 PF12048.8 EGG42507.1 - 0.068 12.6 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) FSH1 PF03959.13 EGG42507.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 EGG42507.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Usp PF00582.26 EGG42508.1 - 2.3e-24 86.5 0.0 2.7e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family s48_45 PF07422.13 EGG42508.1 - 0.037 14.6 0.4 0.046 14.3 0.4 1.2 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain PMSR PF01625.21 EGG42509.1 - 3e-67 225.6 0.8 3.2e-67 225.5 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Calycin_like PF13944.6 EGG42511.1 - 0.02 15.2 2.0 0.042 14.2 1.8 1.6 1 1 0 1 1 1 0 Calycin-like beta-barrel domain Methyltransf_11 PF08241.12 EGG42512.1 - 9.6e-11 42.2 0.0 1.7e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG42512.1 - 3.3e-05 24.5 0.0 5.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG42512.1 - 0.00021 21.1 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG42512.1 - 0.0028 18.4 0.0 0.0047 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG42512.1 - 0.003 17.4 0.0 0.0063 16.4 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EGG42512.1 - 0.14 11.7 0.0 0.78 9.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain RDD PF06271.12 EGG42513.1 - 1e-08 35.5 0.2 1.4e-08 35.1 0.2 1.2 1 0 0 1 1 1 1 RDD family DUF4113 PF13438.6 EGG42515.1 - 0.0045 17.1 0.0 32 4.7 0.0 3.0 3 0 0 3 3 3 3 Domain of unknown function (DUF4113) Aminotran_3 PF00202.21 EGG42517.1 - 3e-49 167.8 0.1 3.7e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TPR_1 PF00515.28 EGG42518.1 - 1.9e-34 116.1 20.6 3.6e-06 26.6 0.0 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42518.1 - 3e-34 114.3 10.5 0.00023 21.0 0.0 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGG42518.1 - 5.8e-24 83.5 12.2 0.001 18.7 0.0 6.7 2 1 5 7 7 7 5 TPR repeat TPR_8 PF13181.6 EGG42518.1 - 8.8e-22 75.5 16.8 5.2e-05 23.1 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 EGG42518.1 - 1.6e-21 75.0 15.2 8.3e-05 22.7 0.2 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGG42518.1 - 2.4e-21 74.9 0.5 0.091 13.4 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGG42518.1 - 4.5e-20 72.0 0.0 7.7e-05 23.3 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42518.1 - 2.6e-19 69.5 2.4 2.9e-05 24.5 0.2 4.4 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGG42518.1 - 3.5e-19 67.9 0.0 0.021 15.6 0.0 7.1 1 1 6 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG42518.1 - 2.1e-18 66.3 1.0 1.4e-05 25.3 0.0 4.9 3 2 2 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG42518.1 - 1.9e-17 63.3 4.5 4.2e-06 26.9 0.8 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGG42518.1 - 2e-10 40.2 4.4 0.084 12.8 0.8 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGG42518.1 - 1.6e-09 37.8 0.0 0.0011 19.0 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG42518.1 - 3.8e-08 32.8 0.0 0.15 12.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42518.1 - 2.2e-07 30.8 7.4 0.21 11.7 0.1 5.2 3 1 2 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 EGG42518.1 - 7.1e-06 26.3 3.4 0.15 12.4 0.1 3.7 1 1 3 5 5 5 2 Tetratricopeptide repeat MIT PF04212.18 EGG42518.1 - 2.1e-05 24.5 10.0 1.5 8.9 0.1 6.1 5 2 2 7 7 7 1 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 EGG42518.1 - 2.4e-05 23.5 6.8 0.085 11.8 0.2 3.5 1 1 4 5 5 5 4 NMDA receptor-regulated protein 1 ChAPs PF09295.10 EGG42518.1 - 0.0015 17.6 0.6 0.0056 15.7 0.1 1.9 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 EGG42518.1 - 0.0027 17.3 0.0 0.33 10.6 0.0 2.6 2 2 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) MerR_1 PF13411.6 EGG42518.1 - 0.0034 17.4 0.4 0.16 12.1 0.1 2.4 2 0 0 2 2 2 1 MerR HTH family regulatory protein PknG_TPR PF16918.5 EGG42518.1 - 0.0064 15.3 0.0 1 8.0 0.0 2.0 1 1 1 2 2 2 2 Protein kinase G tetratricopeptide repeat TOM20_plant PF06552.12 EGG42518.1 - 0.007 16.1 2.7 5.6 6.7 0.0 4.2 2 2 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 PPR PF01535.20 EGG42518.1 - 0.021 15.1 2.4 34 5.0 0.0 4.9 6 0 0 6 6 4 0 PPR repeat RAP-1 PF03085.15 EGG42518.1 - 0.057 13.1 2.0 0.3 10.7 0.2 2.4 2 1 1 3 3 3 0 Rhoptry-associated protein 1 (RAP-1) Rapsyn_N PF10579.9 EGG42518.1 - 0.065 13.3 0.2 2.6 8.2 0.0 3.4 2 2 2 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_3 PF07720.12 EGG42518.1 - 0.078 13.0 4.1 2.9 8.0 0.2 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Sod_Ni PF09055.11 EGG42518.1 - 0.17 12.4 2.4 0.37 11.3 0.9 2.0 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase AlphaC_C PF17480.2 EGG42518.1 - 0.23 11.5 2.1 7.5 6.7 0.0 3.4 3 1 1 4 4 4 0 AlphaC C-terminal s48_45 PF07422.13 EGG42518.1 - 0.34 11.5 3.1 2.6 8.7 3.1 2.4 1 1 0 1 1 1 0 Sexual stage antigen s48/45 domain DUF4919 PF16266.5 EGG42518.1 - 0.48 10.4 7.8 2.9 7.8 0.2 3.8 2 2 3 5 5 5 0 Domain of unknown function (DUF4919) TPPII_N PF12583.8 EGG42518.1 - 5.7 7.5 7.8 3.2 8.3 0.6 3.2 4 0 0 4 4 3 0 Tripeptidyl peptidase II N terminal Cupin_2 PF07883.11 EGG42519.1 - 6.1e-08 32.3 0.1 3.8e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EGG42519.1 - 3.2e-07 30.1 0.0 4.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.16 EGG42519.1 - 0.00077 19.2 0.1 0.00093 18.9 0.1 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_4 PF08007.12 EGG42519.1 - 0.0042 16.6 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGG42519.1 - 0.0074 16.0 0.0 0.0094 15.7 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.19 EGG42519.1 - 0.0084 16.0 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 AraC-like ligand binding domain MAP PF03642.13 EGG42519.1 - 0.14 12.5 6.0 0.15 12.3 0.8 3.0 2 2 1 3 3 3 0 MAP domain SH3_2 PF07653.17 EGG42519.1 - 0.14 11.8 0.0 0.43 10.3 0.0 1.8 1 1 1 2 2 2 0 Variant SH3 domain Cupin_2 PF07883.11 EGG42520.1 - 2.3e-12 46.5 0.0 4.6e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.18 EGG42520.1 - 2.4e-09 37.3 0.0 2.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 EGG42520.1 - 0.00031 20.4 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 EGG42520.1 - 0.00047 20.1 0.0 0.00065 19.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Ectoine_synth PF06339.12 EGG42520.1 - 0.001 19.3 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Ectoine synthase CENP-C_C PF11699.8 EGG42520.1 - 0.0023 18.1 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_1 PF00190.22 EGG42520.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_5 PF06172.11 EGG42520.1 - 0.045 13.9 0.0 0.061 13.5 0.0 1.5 1 1 0 1 1 1 0 Cupin superfamily (DUF985) GPI PF06560.11 EGG42520.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DnaJ PF00226.31 EGG42521.1 - 1.6e-15 57.0 1.1 4e-15 55.7 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 EGG42521.1 - 5.7e-10 39.6 1.3 1.6e-09 38.2 1.3 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EGG42521.1 - 8.6e-06 26.4 3.2 6.5e-05 23.6 3.2 2.3 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 EGG42521.1 - 0.0045 17.0 1.3 0.011 15.7 1.3 1.6 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 EGG42521.1 - 0.095 12.6 9.9 0.93 9.4 5.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain SRR PF07709.11 EGG42521.1 - 6.2 7.7 5.9 4.3 8.2 0.1 3.3 3 0 0 3 3 3 0 Seven Residue Repeat HIT PF01230.23 EGG42522.1 - 3.4e-22 79.0 0.7 4.2e-22 78.7 0.7 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGG42522.1 - 2.1e-11 44.3 0.1 2.9e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGG42522.1 - 0.0017 18.2 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EGG42522.1 - 0.023 14.4 0.2 0.028 14.2 0.2 1.2 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain ProQ_C PF17516.2 EGG42523.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ProQ C-terminal domain zf-C2H2 PF00096.26 EGG42524.1 - 0.028 14.9 3.0 0.044 14.3 3.0 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG42524.1 - 0.047 14.6 2.5 0.065 14.1 2.5 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger HATPase_c PF02518.26 EGG42525.1 - 7.6e-23 81.2 1.0 1.6e-22 80.1 1.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MEDS PF14417.6 EGG42525.1 - 2e-13 50.5 0.0 3.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HisKA PF00512.25 EGG42525.1 - 5.3e-12 45.6 0.0 1.9e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EGG42525.1 - 1.3e-07 31.4 1.2 1.3e-07 31.4 1.2 2.0 2 0 0 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 EGG42525.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF5025 PF16428.5 EGG42525.1 - 0.014 15.6 0.5 0.031 14.4 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5025) Cyc-maltodext_N PF09087.11 EGG42525.1 - 0.022 15.0 0.9 5.3 7.4 0.1 3.1 2 1 1 3 3 3 0 Cyclomaltodextrinase, N-terminal Cdc13_OB2 PF18691.1 EGG42525.1 - 0.041 14.0 0.7 0.041 14.0 0.7 3.2 2 1 1 3 3 3 0 Cell division control protein 13, OB2 domain DUF3800 PF12686.7 EGG42525.1 - 0.046 14.3 0.5 0.046 14.3 0.5 2.2 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) HATPase_c_3 PF13589.6 EGG42525.1 - 0.049 13.5 0.5 0.14 12.0 0.4 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma70_r1_1 PF03979.14 EGG42525.1 - 0.057 13.5 0.1 0.24 11.5 0.1 2.1 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 tRNA-synt_His PF13393.6 EGG42525.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Yippee-Mis18 PF03226.14 EGG42526.1 - 0.0002 21.5 0.5 0.0003 21.0 0.5 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EGG42526.1 - 0.0045 17.2 0.7 0.0078 16.4 0.7 1.5 1 0 0 1 1 1 1 C-terminal domain of RIG-I 3HCDH_N PF02737.18 EGG42527.1 - 2.9e-65 219.5 0.6 2.9e-65 219.5 0.6 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGG42527.1 - 3e-33 114.3 0.2 2.9e-26 91.9 0.1 2.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EGG42527.1 - 2.2e-05 24.5 0.1 3.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EGG42527.1 - 0.00013 22.2 0.1 0.00023 21.4 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG42527.1 - 0.061 13.9 1.4 0.23 12.0 1.4 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EGG42527.1 - 0.064 12.8 0.3 0.12 11.9 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 EGG42527.1 - 0.3 10.6 3.0 22 4.6 3.0 2.4 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF643 PF04867.12 EGG42527.1 - 2.5 8.7 6.7 0.82 10.3 0.5 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF643) LDcluster4 PF18306.1 EGG42528.1 - 4.9e-46 156.2 2.1 5.6e-46 156.0 2.1 1.0 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 EGG42528.1 - 6.4e-05 23.1 0.0 0.00019 21.5 0.0 2.0 1 1 0 1 1 1 1 Possible lysine decarboxylase LSDAT_prok PF18171.1 EGG42528.1 - 0.00019 20.8 0.6 0.00092 18.5 0.1 1.9 2 0 0 2 2 2 1 SLOG in TRPM, prokaryote DNA_processg_A PF02481.15 EGG42528.1 - 0.00032 20.0 0.7 0.0045 16.3 0.2 2.2 2 1 0 2 2 2 1 DNA recombination-mediator protein A DAGK_cat PF00781.24 EGG42528.1 - 0.0033 17.0 3.4 0.13 11.9 0.1 2.2 1 1 0 2 2 2 2 Diacylglycerol kinase catalytic domain cpYpsA PF12694.7 EGG42528.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family KR PF08659.10 EGG42528.1 - 0.36 10.7 1.7 4.6 7.1 0.1 2.5 3 0 0 3 3 3 0 KR domain zf-C4pol PF14260.6 EGG42529.1 - 0.0023 18.3 10.6 0.99 9.9 0.2 3.2 3 0 0 3 3 3 3 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 EGG42529.1 - 0.0053 16.8 14.6 0.052 13.6 2.4 3.1 2 2 0 2 2 2 2 Double zinc ribbon DUF3179 PF11376.8 EGG42529.1 - 0.016 14.6 0.1 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3179) Ribosomal_S14 PF00253.21 EGG42529.1 - 0.018 14.8 2.9 4.3 7.2 0.4 3.3 3 1 0 3 3 3 0 Ribosomal protein S14p/S29e Prok-RING_4 PF14447.6 EGG42529.1 - 0.087 12.7 18.4 0.094 12.6 0.5 4.5 4 1 1 5 5 5 0 Prokaryotic RING finger family 4 Cytochrome_C7 PF14522.6 EGG42529.1 - 0.19 11.7 15.9 0.64 10.1 4.3 3.0 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF4428 PF14471.6 EGG42529.1 - 0.68 9.9 23.4 1 9.3 0.7 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4428) HNH_5 PF14279.6 EGG42529.1 - 0.8 9.6 18.4 2.6 7.9 0.2 4.9 4 2 1 6 6 6 0 HNH endonuclease Cytochrom_c3_2 PF14537.6 EGG42529.1 - 4 8.0 16.5 1.1e+03 0.1 16.5 3.3 1 1 0 1 1 1 0 Cytochrome c3 zf-C2H2 PF00096.26 EGG42530.1 - 1e-07 32.0 9.5 0.00049 20.4 1.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGG42530.1 - 4.1e-06 26.9 11.5 0.00014 22.0 2.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGG42530.1 - 6.2e-06 26.6 9.0 0.0045 17.7 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGG42530.1 - 4.6e-05 23.6 7.8 0.014 15.7 0.6 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 EGG42530.1 - 0.00061 20.5 2.2 0.0042 17.8 2.2 1.8 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 EGG42530.1 - 0.00069 19.5 8.9 0.013 15.4 1.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGG42530.1 - 0.0013 19.1 14.0 0.011 16.1 0.5 2.9 3 0 0 3 3 3 2 Zinc-finger double domain DUF629 PF04780.12 EGG42530.1 - 0.0018 16.9 9.7 0.068 11.7 1.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf_UBZ PF18439.1 EGG42530.1 - 0.0029 17.2 4.4 0.27 10.8 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf_ZIC PF18366.1 EGG42530.1 - 0.0045 17.0 0.5 0.0045 17.0 0.5 2.1 1 1 1 2 2 2 1 Zic proteins zinc finger domain zf-C2HE PF16278.5 EGG42530.1 - 0.0067 16.9 8.9 0.062 13.8 8.9 1.9 1 1 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DUF1644 PF07800.12 EGG42530.1 - 0.009 16.1 2.5 0.01 15.9 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) zf-C2H2_2 PF12756.7 EGG42530.1 - 0.029 14.7 9.7 0.26 11.6 2.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 EGG42530.1 - 0.032 14.3 1.7 0.032 14.3 1.7 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_8 PF15909.5 EGG42530.1 - 0.11 12.9 2.8 0.13 12.6 2.8 1.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon C1_4 PF07975.12 EGG42530.1 - 0.11 12.8 5.3 0.19 12.0 5.1 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain Ta0938 PF11494.8 EGG42530.1 - 0.26 11.6 2.9 5.7 7.3 2.6 2.0 1 1 0 1 1 1 0 Ta0938 Zn-ribbon_8 PF09723.10 EGG42530.1 - 0.26 11.4 3.9 1.5 9.0 0.5 2.1 2 0 0 2 2 2 0 Zinc ribbon domain FOXP-CC PF16159.5 EGG42530.1 - 0.3 11.8 0.4 0.3 11.8 0.4 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain Actin_micro PF17003.5 EGG42530.1 - 0.32 10.1 12.0 0.83 8.8 2.8 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-MYST PF17772.1 EGG42530.1 - 0.55 9.9 4.8 2.1 8.0 0.4 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain Prok-RING_2 PF14445.6 EGG42530.1 - 0.8 9.9 4.0 7 6.9 4.0 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 DNA_RNApol_7kD PF03604.13 EGG42531.1 - 0.0024 17.5 2.2 0.0057 16.3 2.2 1.6 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S10 PF00338.22 EGG42532.1 - 6.1e-23 80.9 0.0 6.8e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CTX_RstB PF07459.11 EGG42532.1 - 0.032 14.4 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 CTX phage RstB protein GTP_EFTU PF00009.27 EGG42533.1 - 7.6e-46 156.1 0.1 9.8e-46 155.7 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGG42533.1 - 2.6e-37 127.5 0.2 6.2e-37 126.3 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGG42533.1 - 8.6e-16 58.1 1.2 3e-15 56.3 1.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EGG42533.1 - 1e-05 25.4 1.1 2.3e-05 24.2 1.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 NIF3 PF01784.18 EGG42533.1 - 0.084 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) FBPase_3 PF01950.16 EGG42534.1 - 4.2e-151 503.2 0.0 4.7e-151 503.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase MASE3 PF17159.4 EGG42535.1 - 0.00046 19.9 1.0 0.00068 19.3 1.0 1.2 1 0 0 1 1 1 1 Membrane-associated sensor domain MFS_1 PF07690.16 EGG42535.1 - 0.0033 16.4 1.0 0.0038 16.2 1.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5447 PF17525.2 EGG42535.1 - 0.036 14.5 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5447) DNA_ligase_A_M PF01068.21 EGG42536.1 - 5.9e-61 205.7 0.7 1.1e-60 204.8 0.7 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGG42536.1 - 1.4e-33 116.7 2.2 4.6e-33 115.0 1.3 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGG42536.1 - 5.2e-22 78.3 0.0 1.1e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGG42536.1 - 1.7e-07 31.7 0.3 3e-07 30.9 0.3 1.4 1 0 0 1 1 1 1 RNA ligase PhoU_div PF01865.16 EGG42537.1 - 2e-19 69.8 10.2 2.4e-19 69.5 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 PhoU PF01895.19 EGG42537.1 - 0.00063 20.2 11.6 0.0097 16.4 1.9 2.9 2 1 1 3 3 3 2 PhoU domain HATPase_c_5 PF14501.6 EGG42537.1 - 0.066 13.1 0.7 0.066 13.1 0.7 2.1 2 0 0 2 2 2 0 GHKL domain WD40_alt PF14077.6 EGG42537.1 - 0.2 11.6 0.3 0.2 11.6 0.3 2.4 3 0 0 3 3 3 0 Alternative WD40 repeat motif Lzipper-MIP1 PF14389.6 EGG42537.1 - 0.56 10.6 6.5 0.33 11.3 1.2 2.7 2 2 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 MCPsignal PF00015.21 EGG42537.1 - 0.6 9.9 11.2 12 5.6 9.3 3.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2203 PF09969.9 EGG42537.1 - 2.4 8.9 6.7 5.9 7.6 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) S6OS1 PF15676.5 EGG42537.1 - 9.1 4.6 9.2 0.68 8.3 3.0 2.0 2 1 0 2 2 2 0 Six6 opposite strand transcript 1 family tRNA_int_endo PF01974.17 EGG42538.1 - 6.4e-27 93.5 0.0 9.7e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGG42538.1 - 3.1e-17 62.0 0.0 5.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain adh_short PF00106.25 EGG42541.1 - 1e-38 132.8 0.1 2.9e-32 111.7 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG42541.1 - 1.1e-32 113.5 0.1 8.7e-24 84.4 0.0 3.4 4 0 0 4 4 4 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG42541.1 - 3.4e-13 49.9 0.0 1.1e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EGG42541.1 - 8e-07 28.8 0.1 4.1e-06 26.4 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG42541.1 - 0.011 14.9 0.1 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EGG42541.1 - 0.04 14.5 0.3 0.18 12.4 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF787 PF05619.11 EGG42541.1 - 0.39 9.8 2.4 1.3 8.1 0.0 2.4 3 0 0 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF787) RNA_pol_Rbc25 PF08292.12 EGG42542.1 - 0.052 13.8 0.4 0.16 12.2 0.4 1.9 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Gal4_dimer PF03902.13 EGG42542.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF667 PF05018.13 EGG42543.1 - 0.022 14.5 0.4 0.026 14.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF667) Peptidase_M10 PF00413.24 EGG42544.1 - 0.0001 22.2 1.1 0.0019 18.1 1.1 2.5 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 EGG42544.1 - 0.00041 19.4 0.0 0.00078 18.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 EGG42544.1 - 0.0007 19.3 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EGG42544.1 - 0.0012 19.3 0.3 0.005 17.3 0.0 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 EGG42544.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A DUF4953 PF16313.5 EGG42544.1 - 0.0017 17.6 0.1 0.0031 16.8 0.1 1.4 1 0 0 1 1 1 1 Met-zincin Reprolysin_5 PF13688.6 EGG42544.1 - 0.0058 16.8 0.2 0.011 15.8 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 EGG42544.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.11 EGG42544.1 - 0.025 14.5 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_2 PF13574.6 EGG42544.1 - 0.058 13.3 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EGG42544.1 - 0.14 11.8 2.9 0.32 10.6 0.8 2.1 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase Zincin_1 PF06262.11 EGG42544.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Zincin-like metallopeptidase TauE PF01925.19 EGG42545.1 - 3.2e-53 180.8 33.8 3.8e-53 180.6 33.8 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE PMP22_Claudin PF00822.20 EGG42545.1 - 1.1 9.1 7.2 0.14 12.0 1.9 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF192 PF02643.15 EGG42547.1 - 1.8e-29 101.7 0.0 2.3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 NitrOD1 PF18549.1 EGG42548.1 - 3e-45 152.0 2.8 3.3e-45 151.9 2.8 1.0 1 0 0 1 1 1 1 Nitrosopumilus output domain 1 YolD PF08863.10 EGG42548.1 - 0.004 17.2 1.7 0.77 9.9 0.1 2.1 1 1 0 2 2 2 2 YolD-like protein Claudin_2 PF13903.6 EGG42550.1 - 0.0013 18.5 3.0 0.0015 18.3 3.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 EGG42550.1 - 0.0041 17.4 5.7 0.0041 17.4 5.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) PEMT PF04191.13 EGG42550.1 - 0.054 13.9 0.3 0.054 13.9 0.3 1.8 1 1 1 2 2 2 0 Phospholipid methyltransferase DUF2721 PF11026.8 EGG42550.1 - 0.34 10.8 5.9 0.53 10.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) ATP-synt_C PF00137.21 EGG42550.1 - 0.56 10.6 9.3 1.1 9.6 0.5 2.3 1 1 2 3 3 3 0 ATP synthase subunit C ABC2_membrane_3 PF12698.7 EGG42550.1 - 1.1 8.4 9.6 1.2 8.2 9.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.16 EGG42551.1 - 1.6e-34 119.4 34.5 1.6e-34 119.4 34.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG42551.1 - 7.9e-32 110.7 30.8 2.2e-23 82.9 10.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EGG42551.1 - 5.2e-05 22.0 9.2 5.2e-05 22.0 9.2 2.3 1 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EGG42551.1 - 0.025 13.4 21.4 0.022 13.6 7.8 3.5 2 2 1 3 3 3 0 MFS_1 like family Pex24p PF06398.11 EGG42551.1 - 0.33 9.9 1.7 0.66 8.9 1.7 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CPBP PF02517.16 EGG42551.1 - 8.5 6.8 13.0 2.2 8.7 5.9 3.3 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease DUF4747 PF15931.5 EGG42553.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4747) Fe_dep_repress PF01325.19 EGG42555.1 - 2.8e-17 62.7 1.6 4.3e-17 62.1 1.6 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 EGG42555.1 - 3e-17 62.5 0.1 5.3e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain DUF4423 PF14394.6 EGG42555.1 - 5.4e-07 29.5 0.1 1.7e-05 24.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) MarR_2 PF12802.7 EGG42555.1 - 0.00013 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EGG42555.1 - 0.00033 20.5 0.1 0.00099 19.0 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 EGG42555.1 - 0.00035 20.5 0.0 0.00089 19.2 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_45 PF14947.6 EGG42555.1 - 0.00063 19.7 1.0 0.0019 18.1 0.7 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix TrmB PF01978.19 EGG42555.1 - 0.00097 19.0 0.2 0.0019 18.0 0.2 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 EGG42555.1 - 0.0011 19.0 0.6 0.0019 18.3 0.3 1.5 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) RexA PF15969.5 EGG42555.1 - 0.002 17.8 0.1 0.0031 17.1 0.0 1.3 1 1 0 1 1 1 1 Intracellular sensor of Lambda phage, Abi component HTH_12 PF08461.10 EGG42555.1 - 0.0022 17.9 0.1 0.0045 16.9 0.1 1.6 1 1 0 1 1 1 1 Ribonuclease R winged-helix domain HipN PF18253.1 EGG42555.1 - 0.0038 16.9 0.1 0.0084 15.8 0.1 1.6 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain HTH_27 PF13463.6 EGG42555.1 - 0.0054 17.2 0.1 0.023 15.2 0.1 2.0 2 1 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EGG42555.1 - 0.0075 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding WYL_3 PF18488.1 EGG42555.1 - 0.0077 16.6 0.1 0.056 13.8 0.1 2.0 2 0 0 2 2 2 1 WYL domain HTH_IclR PF09339.10 EGG42555.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain NUMOD1 PF07453.13 EGG42555.1 - 0.026 14.8 0.0 8.2 6.8 0.0 3.1 3 0 0 3 3 3 0 NUMOD1 domain LexA_DNA_bind PF01726.16 EGG42555.1 - 0.032 14.0 0.0 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 LexA DNA binding domain TFIIE_alpha PF02002.17 EGG42555.1 - 0.034 14.0 0.4 0.17 11.8 0.1 1.9 1 1 1 2 2 2 0 TFIIE alpha subunit Rio2_N PF09202.11 EGG42555.1 - 0.042 14.1 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 Rio2, N-terminal HTH_1 PF00126.27 EGG42555.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Ribosomal_S19e PF01090.19 EGG42555.1 - 0.046 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e GntR PF00392.21 EGG42555.1 - 0.054 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF2624 PF11116.8 EGG42555.1 - 0.061 14.2 0.3 0.2 12.6 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) CARD PF00619.21 EGG42555.1 - 0.1 12.6 0.1 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Caspase recruitment domain MG2 PF01835.19 EGG42556.1 - 0.0015 18.9 0.0 0.0075 16.7 0.0 2.1 2 1 0 2 2 2 1 MG2 domain Chordopox_G3 PF06129.12 EGG42556.1 - 0.0066 17.1 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 Chordopoxvirus G3 protein T2SSE PF00437.20 EGG42557.1 - 2.7e-12 46.4 0.0 5.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KH_2 PF07650.17 EGG42557.1 - 1.7e-07 31.0 1.9 3.9e-07 29.8 0.2 2.5 2 0 0 2 2 2 1 KH domain KH_1 PF00013.29 EGG42557.1 - 2.5e-07 30.4 0.3 2e-06 27.5 0.1 2.5 2 0 0 2 2 2 1 KH domain AAA_16 PF13191.6 EGG42557.1 - 4.8e-05 23.8 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain KH_5 PF13184.6 EGG42557.1 - 7.2e-05 22.8 1.1 0.00069 19.6 0.2 2.8 2 0 0 2 2 2 1 NusA-like KH domain AAA_25 PF13481.6 EGG42557.1 - 7.8e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGG42557.1 - 9.9e-05 22.4 0.0 0.00067 19.7 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 EGG42557.1 - 0.00016 22.2 0.0 0.002 18.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGG42557.1 - 0.0002 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PIN_4 PF13638.6 EGG42557.1 - 0.00046 20.5 0.3 0.0022 18.3 0.3 2.2 1 1 0 1 1 1 1 PIN domain AAA_22 PF13401.6 EGG42557.1 - 0.00087 19.6 0.1 0.026 14.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EGG42557.1 - 0.0048 17.4 0.0 0.019 15.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter KH_4 PF13083.6 EGG42557.1 - 0.005 16.7 0.1 0.017 15.0 0.1 1.9 1 0 0 1 1 1 1 KH domain AAA PF00004.29 EGG42557.1 - 0.0066 16.9 0.2 0.094 13.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EGG42557.1 - 0.0069 15.4 0.0 0.022 13.8 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PIN_9 PF18477.1 EGG42557.1 - 0.0081 16.5 0.7 0.064 13.6 0.7 2.5 1 1 0 1 1 1 1 PIN like domain AAA_28 PF13521.6 EGG42557.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG42557.1 - 0.015 15.2 0.0 0.062 13.2 0.0 2.1 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 EGG42557.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EGG42557.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGG42557.1 - 0.023 14.9 0.0 0.076 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 EGG42557.1 - 0.03 14.1 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGG42557.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGG42557.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DAP3 PF10236.9 EGG42557.1 - 0.073 12.2 0.0 1.4 8.0 0.0 2.6 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 EGG42557.1 - 0.074 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 EGG42557.1 - 0.098 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 EGG42557.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 EGG42557.1 - 0.11 12.9 0.1 0.53 10.7 0.1 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGG42557.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Response_reg PF00072.24 EGG42558.1 - 1.2e-27 96.3 0.6 1.3e-27 96.1 0.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Hpt PF01627.23 EGG42559.1 - 8.3e-05 22.8 0.0 0.0001 22.5 0.0 1.3 1 1 0 1 1 1 1 Hpt domain KRAP_IP3R_bind PF14722.6 EGG42559.1 - 0.012 15.3 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Vps51 PF08700.11 EGG42559.1 - 0.015 15.3 3.4 0.031 14.3 0.3 2.5 3 1 0 3 3 3 0 Vps51/Vps67 SesA PF17107.5 EGG42559.1 - 0.016 15.4 0.4 0.037 14.2 0.2 1.7 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Seryl_tRNA_N PF02403.22 EGG42559.1 - 0.022 15.0 1.6 0.04 14.2 0.4 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tweety PF04906.13 EGG42559.1 - 0.022 13.5 0.7 0.024 13.3 0.7 1.1 1 0 0 1 1 1 0 Tweety KxDL PF10241.9 EGG42559.1 - 0.031 14.6 1.1 1.2 9.4 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein RPAP3_C PF13877.6 EGG42559.1 - 0.06 13.9 0.1 0.092 13.3 0.1 1.4 1 1 0 1 1 1 0 Potential Monad-binding region of RPAP3 SEO_N PF14576.6 EGG42559.1 - 0.086 12.0 2.9 2.6 7.1 0.7 2.1 1 1 1 2 2 2 0 Sieve element occlusion N-terminus NPV_P10 PF05531.12 EGG42559.1 - 0.18 12.3 2.7 4.3 7.9 0.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AEP1 PF17049.5 EGG42559.1 - 0.24 10.5 5.9 0.15 11.1 1.4 2.0 2 0 0 2 2 2 0 ATPase expression protein 1 MCPsignal PF00015.21 EGG42559.1 - 0.75 9.6 5.0 4.9 6.9 5.1 2.0 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FlaC_arch PF05377.11 EGG42559.1 - 0.84 10.1 8.3 2 8.9 0.8 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) HATPase_c PF02518.26 EGG42560.1 - 1e-26 93.7 0.1 2.6e-26 92.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG42560.1 - 1.8e-15 56.7 1.9 3.1e-15 55.9 0.3 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EGG42560.1 - 6.8e-08 32.8 0.0 2.3e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 HAMP domain PilJ PF13675.6 EGG42560.1 - 4.5e-06 26.7 0.0 0.00036 20.5 0.0 2.8 2 0 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term HATPase_c_3 PF13589.6 EGG42560.1 - 1.8e-05 24.6 0.1 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG42560.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Imm70 PF15601.6 EGG42560.1 - 0.057 13.0 0.7 0.16 11.5 0.2 2.0 2 0 0 2 2 2 0 Immunity protein 70 Myb_DNA-bind_3 PF12776.7 EGG42560.1 - 0.89 10.6 3.2 8 7.5 0.4 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain UDG PF03167.19 EGG42561.1 - 5.6e-40 136.8 0.0 7.4e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Tantalus PF15386.6 EGG42561.1 - 0.031 14.4 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Drosophila Tantalus-like Epimerase_2 PF02350.19 EGG42561.1 - 0.053 12.4 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Pur_DNA_glyco PF02245.16 EGG42562.1 - 2.1e-62 209.7 0.0 2.3e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) SNARE_assoc PF09335.11 EGG42563.1 - 5.9e-16 59.0 0.2 5.9e-16 59.0 0.2 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1418 PF07214.12 EGG42563.1 - 0.017 15.0 1.3 0.025 14.4 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF697 PF05128.12 EGG42563.1 - 0.032 13.9 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Glycophorin_A PF01102.18 EGG42563.1 - 0.038 14.2 0.5 8.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A EF1_GNE PF00736.19 EGG42565.1 - 0.022 14.9 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain DUF1454 PF07305.12 EGG42565.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Memo PF01875.17 EGG42566.1 - 0.025 13.7 0.4 0.037 13.2 0.2 1.3 1 1 0 1 1 1 0 Memo-like protein ABC_tran PF00005.27 EGG42567.1 - 1.8e-25 90.0 0.0 2.5e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EGG42567.1 - 1.2e-17 64.1 0.1 2.1e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EGG42567.1 - 8.1e-06 25.8 0.6 4.5e-05 23.4 0.1 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG42567.1 - 0.006 16.0 0.7 0.012 15.1 0.7 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain PRK PF00485.18 EGG42567.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EGG42567.1 - 0.19 11.5 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyoxalase PF00903.25 EGG42568.1 - 1.3e-14 54.4 0.0 1.6e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGG42568.1 - 3.3e-08 33.8 0.0 1.5e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGG42568.1 - 0.00012 21.9 0.2 0.00047 20.1 0.2 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EGG42568.1 - 0.0022 18.8 0.0 0.0028 18.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EGG42568.1 - 0.048 13.8 0.0 0.093 12.8 0.0 1.4 2 0 0 2 2 2 0 Glyoxalase-like domain KH_5 PF13184.6 EGG42569.1 - 0.036 14.1 0.1 0.079 13.1 0.1 1.7 1 0 0 1 1 1 0 NusA-like KH domain tRNA-synt_2 PF00152.20 EGG42570.1 - 8.4e-89 297.7 0.0 1e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG42570.1 - 1.4e-11 44.2 1.0 2.6e-11 43.3 1.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGG42570.1 - 0.0073 15.8 0.2 0.17 11.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF190 PF02641.15 EGG42572.1 - 0.00053 20.3 0.1 0.00091 19.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized ACR, COG1993 P-II PF00543.22 EGG42572.1 - 0.00071 20.1 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Nit_Regul_Hom PF10126.9 EGG42572.1 - 0.081 12.9 0.3 0.25 11.4 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Sbt_1 PF05982.12 EGG42573.1 - 6.1e-101 337.7 20.5 7e-101 337.5 20.5 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily DUF1772 PF08592.11 EGG42573.1 - 0.019 15.3 6.5 0.61 10.4 2.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) GAS PF13851.6 EGG42573.1 - 0.13 11.6 0.5 0.19 11.1 0.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SnoaL_2 PF12680.7 EGG42576.1 - 1.6e-08 35.1 0.0 1.8e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 EGG42576.1 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain DUF4440 PF14534.6 EGG42576.1 - 0.00059 20.2 0.0 0.00071 19.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 EGG42576.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase CybS PF05328.12 EGG42576.1 - 0.054 13.2 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Iso_dh PF00180.20 EGG42577.1 - 2.7e-101 339.2 0.4 3.1e-101 339.0 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 EGG42577.1 - 0.00071 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA HMGL-like PF00682.19 EGG42578.1 - 4.3e-87 292.0 0.3 7e-87 291.3 0.3 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGG42578.1 - 1.8e-29 102.3 1.2 3.6e-29 101.4 1.2 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4147 PF13660.6 EGG42578.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Glyco_hydro_97 PF10566.9 EGG42578.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 ALS_ss_C PF10369.9 EGG42579.1 - 1.8e-22 79.3 0.8 5.4e-21 74.6 0.0 2.2 2 1 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 EGG42579.1 - 9.2e-15 54.2 0.0 2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 EGG42579.1 - 9.9e-13 47.6 0.0 2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EGG42579.1 - 0.0032 18.0 0.1 0.0081 16.7 0.1 1.7 1 0 0 1 1 1 1 ACT domain ADPrib_exo_Tox PF03496.14 EGG42579.1 - 0.04 13.3 0.5 0.058 12.7 0.5 1.2 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme SLS PF14611.6 EGG42579.1 - 0.043 13.6 0.2 0.046 13.6 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator TPP_enzyme_N PF02776.18 EGG42580.1 - 8.1e-61 204.6 0.2 2.5e-58 196.5 0.1 2.5 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG42580.1 - 9.9e-48 161.4 0.1 2.1e-47 160.3 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGG42580.1 - 1.9e-47 160.9 0.3 3.6e-46 156.7 0.1 2.8 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 EGG42580.1 - 0.037 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate SnoaL_3 PF13474.6 EGG42581.1 - 3e-07 30.7 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 EGG42581.1 - 2.7e-05 24.3 0.0 7.4e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 EGG42581.1 - 0.00015 22.2 0.0 0.0002 21.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Flu_B_M2 PF04772.12 EGG42581.1 - 0.15 12.3 0.7 1 9.6 0.0 2.4 2 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) Saccharop_dh_N PF04455.12 EGG42584.1 - 1e-34 118.9 0.2 2.4e-34 117.7 0.2 1.7 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region TPP_enzyme_M PF00205.22 EGG42584.1 - 0.001 18.8 0.9 0.019 14.7 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DS PF01916.17 EGG42584.1 - 0.017 14.4 1.2 0.26 10.5 0.1 2.6 1 1 2 3 3 3 0 Deoxyhypusine synthase Citrate_bind PF16114.5 EGG42584.1 - 0.043 13.3 0.2 0.28 10.7 0.0 2.3 2 1 1 3 3 3 0 ATP citrate lyase citrate-binding ATPase PF06745.13 EGG42585.1 - 1.9e-59 200.8 0.2 2.3e-59 200.5 0.2 1.0 1 0 0 1 1 1 1 KaiC GvpD PF07088.11 EGG42585.1 - 5.4e-12 45.1 0.0 7.1e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 GvpD gas vesicle protein DnaB_C PF03796.15 EGG42585.1 - 8.1e-06 25.4 0.1 3.6e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 EGG42585.1 - 2.8e-05 23.8 0.0 7.6e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG42585.1 - 0.00046 20.0 0.3 0.00088 19.0 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG42585.1 - 0.00052 20.6 0.7 0.0087 16.6 0.4 2.6 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 EGG42585.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGG42585.1 - 0.0027 18.0 0.1 0.0083 16.4 0.0 1.9 1 1 0 2 2 2 1 AAA domain RecA PF00154.21 EGG42585.1 - 0.0036 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 EGG42585.1 - 0.0049 17.3 0.0 0.0069 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGG42585.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGG42585.1 - 0.013 15.6 0.0 0.064 13.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGG42585.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGG42585.1 - 0.021 14.5 0.0 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 EGG42585.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PPV_E1_C PF00519.17 EGG42585.1 - 0.035 13.0 0.1 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase DUF2075 PF09848.9 EGG42585.1 - 0.05 12.8 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.9 EGG42585.1 - 0.055 12.6 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Terminase_6 PF03237.15 EGG42585.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.8 1 1 1 2 2 2 0 Terminase-like family Viral_helicase1 PF01443.18 EGG42585.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EGG42585.1 - 0.081 13.3 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGG42585.1 - 0.082 12.5 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGG42585.1 - 0.084 13.0 0.1 0.2 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGG42585.1 - 0.086 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Roc PF08477.13 EGG42585.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EGG42585.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrmB PF01978.19 EGG42586.1 - 2.3e-11 43.4 0.0 4.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EGG42586.1 - 0.0058 16.4 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_9 PF08221.11 EGG42586.1 - 0.021 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain BOP1NT PF08145.12 EGG42586.1 - 0.043 13.7 0.4 0.079 12.9 0.1 1.6 2 0 0 2 2 2 0 BOP1NT (NUC169) domain HSBP1 PF06825.12 EGG42586.1 - 0.76 9.7 3.5 0.72 9.7 1.0 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Arc_PepC_II PF06847.11 EGG42587.1 - 6.5e-10 39.4 0.1 2.2e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 Archaeal Peptidase A24 C-terminus Type II Peptidase_A24 PF01478.18 EGG42587.1 - 1.5e-06 28.6 5.7 2.7e-06 27.7 5.7 1.5 1 0 0 1 1 1 1 Type IV leader peptidase family TrmB PF01978.19 EGG42588.1 - 2.7e-12 46.4 0.2 3.9e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EGG42588.1 - 0.0037 17.6 0.2 0.013 15.9 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 EGG42588.1 - 0.0047 16.5 1.9 0.075 12.6 1.9 2.1 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EGG42588.1 - 0.0072 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_9 PF08221.11 EGG42588.1 - 0.013 15.6 0.1 0.033 14.3 0.1 1.7 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_46 PF15977.5 EGG42588.1 - 0.045 13.8 1.7 0.15 12.1 0.2 2.1 1 1 1 2 2 2 0 Winged helix-turn-helix DNA binding RNA_pol_Rpb5_C PF01191.19 EGG42588.1 - 0.051 13.4 0.2 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DUF2250 PF10007.9 EGG42588.1 - 0.064 13.4 0.1 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_Crp_2 PF13545.6 EGG42588.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_27 PF13463.6 EGG42588.1 - 0.13 12.8 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain AMP-binding PF00501.28 EGG42589.1 - 3.8e-79 266.3 0.0 4.6e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG42589.1 - 8.9e-17 61.8 0.0 1.7e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGG42589.1 - 3.7e-10 39.6 2.0 7.4e-10 38.6 2.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ProRS-C_2 PF09181.10 EGG42590.1 - 0.032 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal GatB_N PF02934.15 EGG42591.1 - 9.2e-76 254.8 0.0 1.5e-75 254.1 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGG42591.1 - 1.5e-33 115.7 4.8 3.7e-33 114.5 4.8 1.6 1 0 0 1 1 1 1 GatB domain SpoVIF PF14069.6 EGG42591.1 - 0.019 14.8 1.1 5.9 6.7 0.0 3.1 3 0 0 3 3 3 0 Stage VI sporulation protein F Amidase PF01425.21 EGG42592.1 - 1.6e-136 455.9 0.0 1.8e-136 455.7 0.0 1.0 1 0 0 1 1 1 1 Amidase PUB PF09409.10 EGG42593.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PUB domain tRNA-synt_2 PF00152.20 EGG42594.1 - 9e-80 268.1 0.0 1.1e-79 267.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG42594.1 - 9.2e-12 44.8 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGG42594.1 - 0.005 16.3 0.1 0.17 11.4 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) NVEALA PF14055.6 EGG42595.1 - 0.18 11.8 0.5 1 9.4 0.1 1.9 2 0 0 2 2 2 0 NVEALA protein Sulfolobus_pRN PF05584.11 EGG42596.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein DUF1297 PF06973.12 EGG42597.1 - 5.7e-74 247.7 0.1 7.7e-74 247.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 EGG42597.1 - 4.3e-45 152.6 0.0 7.5e-45 151.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) Hydantoinase_A PF01968.18 EGG42599.1 - 1.1e-61 208.6 4.5 1.1e-61 208.6 4.5 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGG42599.1 - 4e-21 75.5 9.2 5.9e-20 71.7 5.5 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EGG42599.1 - 9e-07 27.8 4.5 9.5e-05 21.2 1.4 2.6 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 EGG42599.1 - 8.1e-06 25.5 2.4 5.5e-05 22.8 0.3 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 EGG42599.1 - 0.00022 20.9 0.9 0.00061 19.4 0.8 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ACT_6 PF13740.6 EGG42599.1 - 0.031 14.2 0.1 0.096 12.7 0.1 1.8 1 0 0 1 1 1 0 ACT domain FTR1 PF03239.14 EGG42600.1 - 1.1e-21 77.4 20.7 5.5e-15 55.3 5.5 2.4 1 1 1 2 2 2 2 Iron permease FTR1 family Tn7_Tnp_TnsA_C PF08721.11 EGG42601.1 - 0.32 11.7 3.7 1.2 9.8 0.4 3.0 1 1 2 3 3 3 0 TnsA endonuclease C terminal Ly49 PF08391.10 EGG42601.1 - 3.2 8.1 10.2 4.5 7.7 1.6 3.3 2 2 1 3 3 3 0 Ly49-like protein, N-terminal region HTH_11 PF08279.12 EGG42602.1 - 4.9e-05 23.2 0.2 8.3e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 EGG42602.1 - 8.6e-05 22.3 0.1 0.00014 21.6 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EGG42602.1 - 0.00015 21.8 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EGG42602.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_40 PF14493.6 EGG42602.1 - 0.00064 20.1 0.2 0.00096 19.6 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EGG42602.1 - 0.00066 19.7 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_IclR PF09339.10 EGG42602.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain Mga PF05043.13 EGG42602.1 - 0.0013 19.3 1.4 0.0045 17.5 0.3 2.0 1 1 1 2 2 2 1 Mga helix-turn-helix domain HTH_23 PF13384.6 EGG42602.1 - 0.0022 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 EGG42602.1 - 0.0033 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 MarR family FUR PF01475.19 EGG42602.1 - 0.0056 16.8 0.2 0.0082 16.3 0.2 1.4 1 1 0 1 1 1 1 Ferric uptake regulator family DUF4423 PF14394.6 EGG42602.1 - 0.007 16.1 0.1 0.008 15.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) DUF1492 PF07374.11 EGG42602.1 - 0.013 15.7 0.1 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) HTH_22 PF13309.6 EGG42602.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 EGG42602.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 EGG42602.1 - 0.04 13.6 0.1 0.076 12.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Fe_dep_repress PF01325.19 EGG42602.1 - 0.043 14.0 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EGG42602.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 EGG42602.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_36 PF13730.6 EGG42602.1 - 0.11 12.5 0.2 0.21 11.5 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 EGG42603.1 - 0.0046 16.8 0.1 0.0053 16.6 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 EGG42603.1 - 0.025 14.7 0.3 0.029 14.5 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PadR PF03551.14 EGG42603.1 - 0.068 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family FUR PF01475.19 EGG42603.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Ferric uptake regulator family Arch_flagellin PF01917.16 EGG42604.1 - 6.7e-21 75.2 11.8 8.4e-21 74.8 11.8 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin VCBS PF13517.6 EGG42604.1 - 0.061 13.9 0.3 0.15 12.7 0.3 1.8 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Arch_flagellin PF01917.16 EGG42605.1 - 1.3e-18 67.7 2.0 2e-18 67.1 2.0 1.3 1 1 0 1 1 1 1 Archaebacterial flagellin Arch_flagellin PF01917.16 EGG42606.1 - 3.4e-21 76.1 7.7 4.4e-21 75.8 7.7 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin IncE PF17627.2 EGG42606.1 - 0.1 12.6 2.2 0.18 11.9 2.2 1.3 1 0 0 1 1 1 0 Inclusion membrane protein E DUF5325 PF17259.2 EGG42606.1 - 0.1 12.5 2.3 0.48 10.3 2.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Cupredoxin_1 PF13473.6 EGG42607.1 - 6e-05 23.1 0.0 0.00017 21.7 0.0 1.8 2 0 0 2 2 2 1 Cupredoxin-like domain Copper-bind PF00127.20 EGG42607.1 - 0.00017 22.0 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Arch_flagellin PF01917.16 EGG42608.1 - 1.7e-22 80.3 5.3 2.2e-22 80.0 5.3 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin DUF5325 PF17259.2 EGG42608.1 - 0.098 12.5 2.2 0.23 11.3 2.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF2612 PF11041.8 EGG42608.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) Pilin_N PF07790.11 EGG42608.1 - 4.4 8.3 8.6 3 8.8 6.2 2.0 2 1 0 2 2 2 0 Archaeal Type IV pilin, N-terminal TrmB PF01978.19 EGG42609.1 - 5.1e-15 55.1 0.0 1.3e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 EGG42609.1 - 2e-06 27.2 0.2 2.8e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB HTH_5 PF01022.20 EGG42609.1 - 0.0041 16.9 0.0 0.0094 15.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EGG42609.1 - 0.018 15.0 0.0 0.061 13.3 0.0 1.9 1 0 0 1 1 1 0 HTH domain DUF1386 PF07138.11 EGG42609.1 - 0.03 13.6 0.2 0.083 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1386) Bacillus_HBL PF05791.11 EGG42609.1 - 0.038 13.8 0.3 0.076 12.8 0.3 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PNK3P PF08645.11 EGG42609.1 - 0.04 13.6 1.5 0.047 13.4 0.1 1.8 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Cep57_MT_bd PF06657.13 EGG42609.1 - 0.044 14.2 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Pup PF05639.11 EGG42609.1 - 0.19 12.7 0.1 0.41 11.6 0.1 1.6 1 0 0 1 1 1 0 Pup-like protein TPR_1 PF00515.28 EGG42610.1 - 2.6e-49 163.1 29.6 6e-08 32.2 1.3 12.9 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42610.1 - 2e-48 158.7 12.7 4.5e-06 26.4 0.0 14.2 15 0 0 15 15 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42610.1 - 2.8e-39 133.5 2.2 1.1e-07 32.2 0.0 9.0 5 3 5 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGG42610.1 - 4.1e-36 120.2 33.8 4.8e-06 26.4 0.0 14.3 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_14 PF13428.6 EGG42610.1 - 2.6e-32 108.7 0.0 0.0082 16.9 0.0 12.2 5 4 8 13 13 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGG42610.1 - 1.2e-31 109.0 0.0 5e-07 30.3 0.0 7.3 4 1 2 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGG42610.1 - 2.6e-28 97.4 20.6 3.5e-05 23.4 0.0 11.1 7 3 5 12 12 11 8 TPR repeat TPR_6 PF13174.6 EGG42610.1 - 1.3e-26 91.4 0.2 0.06 14.0 0.0 13.2 14 0 0 14 14 13 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG42610.1 - 1.5e-25 89.2 22.9 2.8e-07 30.6 0.0 6.8 2 2 7 9 9 9 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGG42610.1 - 2.1e-23 81.0 20.5 0.001 19.3 0.0 11.1 12 0 0 12 12 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGG42610.1 - 1.2e-22 78.2 5.8 0.02 14.9 0.0 10.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGG42610.1 - 4.2e-19 68.6 15.1 0.00025 21.3 0.1 9.8 4 3 5 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGG42610.1 - 6.5e-16 58.2 0.0 0.0071 16.5 0.0 6.6 2 1 5 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGG42610.1 - 3.4e-11 42.6 0.1 0.98 9.4 0.0 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGG42610.1 - 4.8e-09 36.4 5.5 0.18 12.2 0.0 7.0 4 2 3 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42610.1 - 2.6e-08 33.8 16.8 1 9.5 0.1 8.4 8 2 2 10 10 9 3 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 EGG42610.1 - 9.2e-08 31.4 20.9 0.0052 15.7 1.0 6.8 1 1 5 6 6 6 3 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 EGG42610.1 - 3.1e-06 26.9 0.1 0.61 9.7 0.0 5.2 2 2 2 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 EGG42610.1 - 2e-05 24.2 14.6 0.34 10.3 2.7 4.5 2 1 2 4 4 4 3 Coatomer epsilon subunit TPR_15 PF13429.6 EGG42610.1 - 6.9e-05 22.2 0.2 0.42 9.8 0.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat DUF5588 PF17826.1 EGG42610.1 - 0.00021 20.3 4.5 0.022 13.7 0.2 3.7 3 1 1 4 4 4 1 Family of unknown function (DUF5588) TOM20_plant PF06552.12 EGG42610.1 - 0.00033 20.5 2.3 1.7 8.3 0.1 4.2 3 1 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 Rapsyn_N PF10579.9 EGG42610.1 - 0.00048 20.2 0.0 17 5.6 0.0 5.5 6 0 0 6 6 6 0 Rapsyn N-terminal myristoylation and linker region TPR_21 PF09976.9 EGG42610.1 - 0.0011 18.7 2.8 5 6.8 0.1 4.7 3 1 1 5 5 5 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 EGG42610.1 - 0.0012 19.3 0.0 2.6 8.5 0.0 4.1 3 3 2 5 5 5 1 Bacterial transcriptional activator domain ChAPs PF09295.10 EGG42610.1 - 0.0034 16.5 10.9 0.12 11.3 0.5 4.0 1 1 3 4 4 4 3 ChAPs (Chs5p-Arf1p-binding proteins) DUF4919 PF16266.5 EGG42610.1 - 0.0098 15.9 7.2 0.97 9.3 0.6 4.3 3 2 1 4 4 4 1 Domain of unknown function (DUF4919) MIT PF04212.18 EGG42610.1 - 3.9 7.6 15.6 4.8 7.3 0.0 6.4 6 1 1 7 7 5 0 MIT (microtubule interacting and transport) domain DUF5099 PF17025.5 EGG42610.1 - 8.4 6.8 10.6 2.3 8.7 0.2 3.9 4 1 0 4 4 3 0 Domain of unknown function (DUF5099) Big_1 PF02369.16 EGG42611.1 - 0.00016 21.6 0.4 0.00016 21.6 0.4 4.7 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 EGG42611.1 - 0.00088 19.5 16.7 0.18 12.2 1.4 5.0 5 1 0 5 5 5 3 Invasin, domain 3 Peptidase_M10 PF00413.24 EGG42613.1 - 3e-09 36.9 0.0 3e-09 36.9 0.0 1.2 1 1 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 EGG42613.1 - 6.2e-05 22.7 0.2 9.2e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 EGG42613.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 EGG42613.1 - 0.096 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Response_reg PF00072.24 EGG42614.1 - 1.6e-16 60.4 0.0 2.9e-16 59.6 0.0 1.4 1 1 0 1 1 1 1 Response regulator receiver domain Synapsin PF02078.16 EGG42615.1 - 0.13 12.5 0.1 1.5 9.1 0.1 2.1 2 0 0 2 2 2 0 Synapsin, N-terminal domain LysM PF01476.20 EGG42616.1 - 0.047 13.8 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 LysM domain PAS_9 PF13426.7 EGG42617.1 - 1.3e-17 64.0 1.9 2.7e-17 62.9 0.3 2.4 2 1 1 3 3 3 1 PAS domain HATPase_c PF02518.26 EGG42617.1 - 2.7e-16 60.1 0.3 6e-16 59.0 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG42617.1 - 4.5e-13 49.0 0.3 1.2e-12 47.6 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EGG42617.1 - 8.7e-11 42.0 0.2 1.6e-10 41.1 0.2 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EGG42617.1 - 5.5e-09 36.0 0.1 1.7e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 EGG42617.1 - 7.5e-09 35.4 0.9 2.3e-08 33.9 0.9 1.8 1 0 0 1 1 1 1 GHKL domain PAS_4 PF08448.10 EGG42617.1 - 4.1e-08 33.4 0.0 6.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 EGG42617.1 - 2.1e-05 24.4 0.2 5.9e-05 22.9 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 EGG42617.1 - 0.005 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain E1_FCCH PF16190.5 EGG42617.1 - 0.024 14.8 0.8 2.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain DUF1140 PF06600.11 EGG42617.1 - 0.39 11.2 3.8 4.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) HATPase_c PF02518.26 EGG42618.1 - 5.9e-16 59.0 0.1 5.9e-16 59.0 0.1 2.3 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EGG42618.1 - 9.8e-09 35.0 0.3 9.8e-09 35.0 0.3 2.2 2 0 0 2 2 2 1 GHKL domain HisKA PF00512.25 EGG42618.1 - 1.8e-08 34.3 2.2 1.5e-07 31.3 0.7 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGG42618.1 - 0.0012 18.7 0.7 0.0035 17.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GIT_CC PF16559.5 EGG42618.1 - 0.014 15.2 6.2 0.073 13.0 6.1 2.3 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HATPase_c_2 PF13581.6 EGG42618.1 - 0.033 14.1 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain GvpL_GvpF PF06386.11 EGG42618.1 - 9.8 6.0 7.3 10 6.0 3.3 2.2 1 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF MCPsignal PF00015.21 EGG42619.1 - 7.5e-19 68.2 9.7 2.6e-11 43.7 1.0 2.5 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Ivy PF08816.11 EGG42619.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) K-box PF01486.17 EGG42619.1 - 0.069 13.3 1.8 0.2 11.9 0.3 2.6 2 0 0 2 2 2 0 K-box region PMC2NT PF08066.12 EGG42619.1 - 0.38 11.5 7.4 1.7 9.4 0.5 3.4 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Cob_adeno_trans PF01923.18 EGG42620.1 - 6.5e-53 179.2 0.0 7.4e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase HD_3 PF13023.6 EGG42621.1 - 2.7e-24 86.0 0.3 2.9e-24 85.8 0.3 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGG42621.1 - 8.6e-13 48.4 1.2 1.9e-12 47.3 1.2 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme BTG PF07742.12 EGG42621.1 - 0.025 14.4 0.3 0.035 14.0 0.3 1.3 1 1 0 1 1 1 0 BTG family HD PF01966.22 EGG42621.1 - 0.027 14.7 0.0 0.061 13.6 0.0 1.6 1 1 0 1 1 1 0 HD domain DUF4130 PF13566.6 EGG42621.1 - 0.075 13.1 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Carbpep_Y_N PF05388.11 EGG42621.1 - 0.11 13.1 1.4 0.21 12.1 0.4 1.8 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide DUF1325 PF07039.11 EGG42623.1 - 0.0044 17.1 1.2 0.005 16.9 1.2 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain HTH_56 PF18662.1 EGG42623.1 - 0.0071 16.4 2.5 0.0082 16.2 2.5 1.1 1 0 0 1 1 1 1 Cch helix turn helix domain Hjc PF01870.18 EGG42624.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) R-HINP1I PF11463.8 EGG42624.1 - 0.036 13.5 0.2 0.051 13.0 0.2 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease 3D PF06725.11 EGG42625.1 - 8.5e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 3D domain DUF35_N PF12172.8 EGG42627.1 - 1.9e-05 24.4 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 EGG42627.1 - 0.11 12.5 2.7 0.31 11.1 2.8 1.6 1 1 1 2 2 2 0 Double zinc ribbon zf-C6H2 PF15801.5 EGG42627.1 - 0.31 11.4 6.4 0.16 12.3 4.0 1.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Thiolase_C PF02803.18 EGG42628.1 - 1.2e-12 47.6 0.9 2.7e-12 46.4 0.2 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 EGG42628.1 - 2.2e-09 37.1 0.7 6.4e-08 32.3 0.7 2.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 EGG42628.1 - 0.00013 21.6 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGG42628.1 - 0.009 15.9 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 EGG42628.1 - 0.012 15.6 0.3 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Bac_luciferase PF00296.20 EGG42629.1 - 3.9e-59 200.6 0.0 4.7e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase NTP_transferase PF00483.23 EGG42630.1 - 1.6e-31 109.8 0.6 2.5e-31 109.2 0.6 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGG42630.1 - 2.6e-11 44.1 0.0 3.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGG42630.1 - 0.0043 16.8 0.0 0.0057 16.4 0.0 1.5 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SNARE_assoc PF09335.11 EGG42631.1 - 5.4e-21 75.3 2.6 5.8e-21 75.2 1.8 1.4 1 1 0 1 1 1 1 SNARE associated Golgi protein DUF2085 PF09858.9 EGG42632.1 - 0.34 11.4 4.0 0.082 13.4 0.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Sdh_cyt PF01127.22 EGG42632.1 - 0.45 10.5 6.2 1.4 9.0 1.3 2.0 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4064 PF13273.6 EGG42632.1 - 3.6 7.9 20.9 28 5.1 0.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ATP-grasp PF02222.22 EGG42633.1 - 4.3e-58 195.7 0.0 6.5e-58 195.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EGG42633.1 - 3.2e-12 45.9 0.0 7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EGG42633.1 - 8.2e-07 28.8 0.0 2.3e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGG42633.1 - 0.00016 21.8 0.1 0.00038 20.5 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 EGG42633.1 - 0.0041 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1297 PF06973.12 EGG42633.1 - 0.055 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) AIRC PF00731.20 EGG42634.1 - 9.3e-59 197.3 0.1 1.3e-58 196.7 0.1 1.2 1 0 0 1 1 1 1 AIR carboxylase PrpR_N PF06506.11 EGG42634.1 - 0.0085 15.7 0.2 0.071 12.7 0.0 2.4 2 1 1 3 3 3 1 Propionate catabolism activator Asp_Glu_race PF01177.22 EGG42634.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.5 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase PALP PF00291.25 EGG42635.1 - 5.3e-17 62.2 0.0 1.1e-16 61.1 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 EGG42635.1 - 7.6e-05 22.4 0.8 0.00015 21.4 0.1 1.8 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 EGG42635.1 - 0.00019 22.0 0.2 0.00035 21.1 0.2 1.4 1 0 0 1 1 1 1 ACT domain Thr_dehydrat_C PF00585.18 EGG42635.1 - 0.0018 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase PALP PF00291.25 EGG42636.1 - 9.5e-55 186.1 0.3 1.1e-54 185.9 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3409 PF11889.8 EGG42636.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) 3HCDH_N PF02737.18 EGG42637.1 - 0.15 11.9 0.2 0.22 11.4 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MRP-S23 PF10484.9 EGG42637.1 - 0.39 11.0 7.0 0.18 12.1 1.2 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 Guanylate_cyc PF00211.20 EGG42638.1 - 4.6e-15 55.7 0.0 6.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DivIC PF04977.15 EGG42639.1 - 0.099 12.4 0.7 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Septum formation initiator KASH_CCD PF14662.6 EGG42639.1 - 0.3 10.9 7.5 0.23 11.3 1.9 2.6 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH Glyoxalase_2 PF12681.7 EGG42641.1 - 1e-08 35.1 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EGG42641.1 - 5.3e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGG42641.1 - 0.0015 19.3 0.0 0.0018 19.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EGG42641.1 - 0.0036 17.6 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AsnC_trans_reg PF01037.21 EGG42642.1 - 7.2e-07 29.1 0.0 7.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain AsnC_trans_reg PF01037.21 EGG42643.1 - 0.0057 16.6 0.7 0.0071 16.3 0.7 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HATPase_c PF02518.26 EGG42645.1 - 3e-17 63.1 0.5 3e-17 63.1 0.5 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG42645.1 - 5.1e-10 39.2 2.1 2.6e-08 33.8 0.0 3.2 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 EGG42645.1 - 9.8e-08 31.8 0.2 2.5e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 EGG42645.1 - 0.0043 16.9 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG42645.1 - 0.061 13.3 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain IL22 PF14565.6 EGG42645.1 - 1.1 9.5 4.4 0.51 10.6 1.8 1.7 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor AAA_32 PF13654.6 EGG42645.1 - 4 6.1 8.4 3.6 6.3 4.9 2.0 2 0 0 2 2 2 0 AAA domain Response_reg PF00072.24 EGG42648.1 - 2.2e-11 43.9 0.1 2.6e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain PelG PF16933.5 EGG42649.1 - 0.051 12.4 0.5 0.066 12.1 0.5 1.1 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) Pyr_redox_2 PF07992.14 EGG42651.1 - 4.3e-34 118.1 0.0 5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG42651.1 - 5.7e-08 33.2 0.4 2.8e-07 31.0 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF835 PF05763.12 EGG42651.1 - 0.075 12.8 1.3 0.17 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Zf_RING PF16744.5 EGG42652.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger HEPN_RiboL-PSP PF18735.1 EGG42652.1 - 0.69 9.8 13.8 1.1 9.2 13.1 1.7 1 1 1 2 2 2 0 RiboL-PSP-HEPN Usp PF00582.26 EGG42653.1 - 4.3e-18 66.2 0.0 5.2e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Response_reg PF00072.24 EGG42654.1 - 1e-15 57.8 0.1 1.5e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain PPP1R35_C PF15503.6 EGG42654.1 - 0.056 13.3 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus TIR-like PF10137.9 EGG42654.1 - 0.069 13.1 0.4 0.54 10.2 0.0 2.1 2 1 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain Response_reg PF00072.24 EGG42655.1 - 6.9e-24 84.2 0.1 8.7e-24 83.9 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGG42656.1 - 3.7e-16 59.6 0.0 9.6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG42656.1 - 1.6e-07 31.2 0.0 5.4e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain LapA_dom PF06305.11 EGG42656.1 - 0.0078 16.0 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Response_reg PF00072.24 EGG42657.1 - 2.3e-14 53.5 0.4 2.7e-14 53.3 0.4 1.1 1 0 0 1 1 1 1 Response regulator receiver domain NHL PF01436.21 EGG42659.1 - 1.5e-11 43.7 6.4 0.48 10.6 0.0 7.3 7 1 1 8 8 8 3 NHL repeat Lactonase PF10282.9 EGG42659.1 - 1.7e-08 34.2 1.9 0.18 11.0 0.0 4.6 1 1 4 5 5 5 4 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 EGG42659.1 - 4e-05 23.7 14.6 4.3 7.6 0.1 6.0 4 1 2 6 6 6 3 Arylesterase Cytochrom_D1 PF02239.16 EGG42659.1 - 0.00011 20.9 4.2 0.13 10.8 0.2 2.9 1 1 2 4 4 4 2 Cytochrome D1 heme domain Glu_cyclase_2 PF05096.12 EGG42659.1 - 0.0049 16.3 4.0 0.21 11.0 1.4 2.3 1 1 1 2 2 2 2 Glutamine cyclotransferase SBBP PF06739.11 EGG42659.1 - 0.01 15.8 5.5 3.5 7.7 0.1 4.9 5 0 0 5 5 5 0 Beta-propeller repeat SGL PF08450.12 EGG42659.1 - 0.017 14.7 5.4 2.3 7.7 0.4 3.6 1 1 2 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region HPS3_N PF14761.6 EGG42659.1 - 0.021 14.4 0.2 0.13 11.8 0.0 2.2 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 ANAPC4_WD40 PF12894.7 EGG42659.1 - 0.034 14.4 1.5 5.1 7.5 0.0 3.3 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GDPD PF03009.17 EGG42659.1 - 0.065 13.0 0.0 0.21 11.3 0.0 1.7 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family FHA PF00498.26 EGG42659.1 - 8 6.9 6.7 25 5.3 0.1 3.7 2 1 2 4 4 4 0 FHA domain Response_reg PF00072.24 EGG42660.1 - 3.4e-28 98.1 0.7 3.8e-28 97.9 0.7 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.18 EGG42661.1 - 7.1e-51 172.5 0.3 9.4e-51 172.1 0.3 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 EGG42661.1 - 1.4e-11 43.9 0.8 2.5e-11 43.1 0.1 1.8 2 0 0 2 2 2 1 CheR methyltransferase, all-alpha domain Methyltransf_31 PF13847.6 EGG42661.1 - 9.4e-08 32.0 2.4 1.6e-06 28.0 1.5 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG42661.1 - 1.7e-07 31.9 0.3 1.6e-05 25.5 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG42661.1 - 1.9e-06 28.4 0.1 2e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG42661.1 - 2.1e-06 28.4 0.0 0.00075 20.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG42661.1 - 6.7e-05 22.8 0.0 9.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGG42661.1 - 0.095 12.3 0.1 0.22 11.1 0.0 1.6 1 1 1 2 2 2 0 Nodulation protein S (NodS) CheD PF03975.13 EGG42662.1 - 4.6e-15 55.7 0.1 6e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Cu-oxidase_4 PF02578.15 EGG42662.1 - 0.16 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase CheC PF04509.12 EGG42663.1 - 4.8e-12 45.6 0.0 8.8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 CheC-like family CheX PF13690.6 EGG42663.1 - 7.8e-08 32.4 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX CheW PF01584.19 EGG42664.1 - 6.6e-21 74.4 0.1 8.1e-21 74.1 0.1 1.1 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 EGG42665.1 - 7.5e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Hpt domain H-kinase_dim PF02895.14 EGG42665.1 - 9.5e-10 38.7 0.4 3.3e-09 37.0 0.4 2.0 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c PF02518.26 EGG42665.1 - 1.1e-05 25.9 0.9 2.9e-05 24.5 0.2 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGG42665.1 - 0.0072 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Baculo_PEP_C PF04513.12 EGG42665.1 - 0.078 13.0 1.8 0.68 10.0 0.1 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CheB_methylest PF01339.17 EGG42666.1 - 1.2e-58 197.5 0.1 3.2e-58 196.2 0.0 1.7 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 EGG42666.1 - 2.6e-17 63.0 0.4 5.8e-17 61.9 0.4 1.6 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.19 EGG42668.1 - 1.1e-34 119.0 0.3 1.5e-34 118.6 0.3 1.1 1 0 0 1 1 1 1 CheW-like domain MCPsignal PF00015.21 EGG42669.1 - 7.6e-39 133.3 46.5 7.9e-38 130.0 23.3 3.6 1 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS PF00989.25 EGG42669.1 - 3.8e-09 36.5 0.3 3.3e-08 33.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGG42669.1 - 7.7e-09 35.8 0.0 3.5e-08 33.6 0.0 2.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EGG42669.1 - 1.4e-08 34.9 0.1 4e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 PAS fold Ferritin PF00210.24 EGG42669.1 - 0.015 15.2 1.4 0.08 12.9 0.0 2.7 1 1 1 3 3 3 0 Ferritin-like domain Stanniocalcin PF03298.13 EGG42669.1 - 0.027 13.8 0.5 1.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Stanniocalcin family PAS_4 PF08448.10 EGG42669.1 - 0.048 13.9 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 PAS fold HisKA PF00512.25 EGG42669.1 - 0.1 12.6 1.2 26 5.0 0.2 3.3 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Spc7 PF08317.11 EGG42669.1 - 0.3 9.9 26.6 0.17 10.7 4.2 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein COG2 PF06148.11 EGG42669.1 - 0.46 10.6 21.6 0.52 10.4 1.9 4.7 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 EGG42669.1 - 0.56 9.9 26.4 3.5 7.3 11.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF745) WXG100 PF06013.12 EGG42669.1 - 1 9.7 12.9 16 5.8 0.0 4.8 3 2 1 4 4 4 0 Proteins of 100 residues with WXG APG17 PF04108.12 EGG42669.1 - 1.6 7.7 21.3 94 1.9 20.7 2.8 1 1 0 1 1 1 0 Autophagy protein Apg17 Fib_alpha PF08702.10 EGG42669.1 - 3.2 7.9 29.5 0.24 11.6 7.1 3.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Cob_adeno_trans PF01923.18 EGG42669.1 - 4.9 7.3 10.1 4.3 7.5 0.9 2.8 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF948 PF06103.11 EGG42669.1 - 7 7.0 32.1 2.9 8.2 2.5 4.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EGG42669.1 - 8 6.5 30.0 0.4 10.7 3.2 4.0 2 2 1 3 3 3 0 Laminin Domain II Sec34 PF04136.15 EGG42669.1 - 8.9 6.2 20.2 0.13 12.1 3.9 3.7 2 2 1 3 3 3 0 Sec34-like family DUF3493 PF11998.8 EGG42670.1 - 0.031 14.4 0.2 0.13 12.4 0.2 2.1 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 T2SSE PF00437.20 EGG42671.1 - 1.3e-43 149.0 0.0 1.8e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 EGG42672.1 - 2.3e-18 66.4 0.5 2.8e-18 66.1 0.5 1.0 1 0 0 1 1 1 1 KaiC Rad51 PF08423.11 EGG42672.1 - 1.7e-06 27.5 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Rad51 DUF835 PF05763.12 EGG42672.1 - 0.0004 20.1 2.7 0.00082 19.1 2.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF835) NACHT PF05729.12 EGG42672.1 - 0.0016 18.4 0.0 0.01 15.8 0.0 2.0 1 1 0 1 1 1 1 NACHT domain PAXNEB PF05625.11 EGG42672.1 - 0.0016 17.7 1.9 0.72 8.9 0.0 2.1 1 1 0 2 2 2 2 PAXNEB protein DUF2075 PF09848.9 EGG42672.1 - 0.0021 17.4 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGG42672.1 - 0.0038 17.6 0.0 0.0053 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGG42672.1 - 0.0044 17.0 0.6 0.0062 16.5 0.6 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 EGG42672.1 - 0.0048 16.6 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 EGG42672.1 - 0.0056 17.0 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Elong_Iki1 PF10483.9 EGG42672.1 - 0.006 16.1 0.7 0.0075 15.8 0.7 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 ResIII PF04851.15 EGG42672.1 - 0.01 15.8 1.4 0.016 15.2 1.4 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EGG42672.1 - 0.014 15.4 1.7 0.42 10.6 1.7 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG42672.1 - 0.015 15.9 0.2 0.19 12.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGG42672.1 - 0.023 14.3 0.0 0.2 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG42672.1 - 0.03 14.2 0.5 0.28 11.1 0.5 2.1 1 1 0 1 1 1 0 NTPase AF2331-like PF14556.6 EGG42672.1 - 0.043 14.4 0.1 0.11 13.1 0.1 1.7 1 0 0 1 1 1 0 AF2331-like NB-ARC PF00931.22 EGG42672.1 - 0.06 12.5 0.3 0.099 11.8 0.3 1.6 1 1 0 1 1 1 0 NB-ARC domain Roc PF08477.13 EGG42672.1 - 0.08 13.2 1.4 0.93 9.7 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EGG42672.1 - 0.1 13.1 0.8 0.2 12.1 0.8 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EGG42672.1 - 0.18 11.1 0.1 0.38 10.1 0.1 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_flagellin PF01917.16 EGG42674.1 - 2e-09 37.8 6.6 2.6e-09 37.5 6.6 1.1 1 0 0 1 1 1 1 Archaebacterial flagellin DUF4352 PF11611.8 EGG42676.1 - 1.8e-11 44.4 1.7 2.2e-11 44.1 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) Aegerolysin PF06355.13 EGG42676.1 - 0.051 13.7 0.2 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 Aegerolysin Rxt3 PF08642.10 EGG42677.1 - 0.0082 16.9 0.0 0.0098 16.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 DUF2299 PF10061.9 EGG42678.1 - 1.9e-18 66.5 0.6 2.4e-18 66.2 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) HAD_SAK_2 PF18143.1 EGG42678.1 - 0.017 15.5 0.1 0.025 14.9 0.1 1.3 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins 5TM-5TMR_LYT PF07694.12 EGG42679.1 - 0.0045 16.5 0.1 0.005 16.4 0.1 1.1 1 0 0 1 1 1 1 5TMR of 5TMR-LYT DUF1129 PF06570.11 EGG42679.1 - 0.013 15.0 0.1 0.013 15.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) RseC_MucC PF04246.12 EGG42679.1 - 0.018 15.0 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Cyt_bd_oxida_I PF01654.17 EGG42679.1 - 0.067 11.8 0.1 0.073 11.7 0.1 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I DUF2407_C PF13373.6 EGG42679.1 - 0.14 12.3 0.3 0.19 11.9 0.3 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain DZR PF12773.7 EGG42680.1 - 0.0002 21.3 0.2 0.00026 21.0 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF35_N PF12172.8 EGG42680.1 - 0.0075 16.1 1.6 0.88 9.5 0.0 2.4 2 1 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 EGG42680.1 - 0.0077 16.3 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 1 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 EGG42680.1 - 0.019 14.6 1.6 1 9.1 0.4 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.12 EGG42680.1 - 0.02 15.1 1.5 0.86 9.9 2.2 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain DpnI PF06044.12 EGG42680.1 - 0.029 14.0 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Dam-replacing family zf-HYPF PF07503.12 EGG42680.1 - 0.038 13.8 2.0 1.5 8.6 0.3 2.4 2 0 0 2 2 2 0 HypF finger zf-C2H2 PF00096.26 EGG42680.1 - 0.05 14.1 1.0 0.72 10.4 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 EGG42680.1 - 0.088 12.7 1.6 7.3 6.6 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EGG42680.1 - 0.16 12.9 1.0 2.6 9.1 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-IS66 PF13005.7 EGG42680.1 - 0.19 12.2 5.0 0.34 11.3 0.2 2.5 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn_ribbon_SprT PF17283.2 EGG42680.1 - 0.27 11.2 3.3 2.3 8.2 3.1 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Ribosomal_L6 PF00347.23 EGG42682.1 - 2.5e-09 37.7 5.1 0.00046 20.8 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 BON PF04972.17 EGG42682.1 - 0.059 13.7 3.8 14 6.1 0.1 3.5 4 1 0 4 4 4 0 BON domain RL10P_insert PF17777.1 EGG42682.1 - 0.11 12.5 0.3 0.6 10.1 0.1 2.1 1 1 1 2 2 2 0 Insertion domain in 60S ribosomal protein L10P Ribosomal_S8 PF00410.19 EGG42683.1 - 6.6e-21 74.6 0.0 7.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 EGG42684.1 - 2.5e-08 33.6 2.7 3.3e-08 33.2 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-FPG_IleRS PF06827.14 EGG42684.1 - 0.058 13.3 3.1 0.12 12.2 3.0 1.7 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS Ribosomal_L5_C PF00673.21 EGG42685.1 - 4.5e-21 74.8 0.0 6.9e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGG42685.1 - 7.9e-11 42.1 0.2 1.3e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S4e PF00900.20 EGG42686.1 - 1.1e-17 63.7 0.2 1.9e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 EGG42686.1 - 1.9e-12 47.1 0.5 3.1e-12 46.4 0.5 1.3 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGG42686.1 - 0.0018 18.0 0.1 0.004 16.8 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EGG42686.1 - 0.025 14.5 0.1 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 KOW motif Ribosomal_L26 PF16906.5 EGG42687.1 - 4.1e-18 65.6 0.4 6.6e-18 65.0 0.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGG42687.1 - 3.2e-05 23.7 0.7 3.2e-05 23.7 0.7 1.8 2 0 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.14 EGG42687.1 - 0.032 13.6 0.4 0.049 13.0 0.2 1.4 1 1 0 1 1 1 0 RNA methyltransferase Ribosomal_L14 PF00238.19 EGG42688.1 - 2.8e-31 108.1 1.3 3.2e-31 107.9 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.20 EGG42689.1 - 4.8e-18 65.0 1.3 6.1e-18 64.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 EGG42689.1 - 0.0013 19.0 0.2 0.0033 17.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal UPF0086 PF01868.16 EGG42690.1 - 1.5e-19 69.7 0.0 1.6e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.23 EGG42691.1 - 1.5e-11 44.1 3.2 1.8e-11 43.8 3.2 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S3_C PF00189.20 EGG42692.1 - 2e-20 73.1 0.9 4.6e-20 71.9 0.9 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGG42692.1 - 3.3e-13 49.3 0.0 8.7e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 EGG42692.1 - 0.03 14.1 0.1 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 KH domain Ribosomal_L22 PF00237.19 EGG42693.1 - 2.6e-26 91.9 0.5 3.4e-26 91.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DNA_pol3_beta_2 PF02767.16 EGG42693.1 - 0.07 13.4 0.1 0.093 12.9 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Ribosomal_S19 PF00203.21 EGG42694.1 - 2e-27 94.9 0.1 2.7e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L23 PF00276.20 EGG42695.1 - 1.9e-13 50.6 0.9 3.3e-13 49.8 0.9 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.19 EGG42695.1 - 0.012 15.3 0.1 0.017 14.8 0.0 1.3 1 1 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain MuF_C PF18819.1 EGG42695.1 - 0.1 12.6 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Phage MuF-C-terminal domain Ribosomal_L4 PF00573.22 EGG42696.1 - 5.3e-09 36.0 0.0 5.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L4 PF00573.22 EGG42697.1 - 3.8e-17 62.6 0.7 4.3e-17 62.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 EGG42698.1 - 4.2e-71 239.9 1.8 9.2e-70 235.5 1.8 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Methyltrn_RNA_3 PF02598.17 EGG42699.1 - 2.4e-51 174.9 0.0 2.7e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Proteasome PF00227.26 EGG42700.1 - 4.9e-52 176.2 0.3 6.2e-52 175.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG42700.1 - 3.4e-14 52.2 0.7 1.4e-13 50.2 0.1 2.3 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF371 PF04027.13 EGG42701.1 - 1.4e-45 154.5 0.1 1.6e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) WbqC PF08889.11 EGG42702.1 - 0.027 14.4 0.7 0.034 14.1 0.7 1.2 1 0 0 1 1 1 0 WbqC-like protein family Snf7 PF03357.21 EGG42703.1 - 2.2e-06 27.4 4.0 3.8e-06 26.6 4.0 1.4 1 1 0 1 1 1 1 Snf7 DUF2073 PF09846.9 EGG42703.1 - 0.065 13.1 2.7 0.95 9.4 0.1 2.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2073) Fib_alpha PF08702.10 EGG42703.1 - 0.07 13.3 6.1 0.045 13.9 4.0 1.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Response_reg PF00072.24 EGG42704.1 - 1.4e-20 73.6 0.4 1.5e-20 73.5 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Aminotran_1_2 PF00155.21 EGG42705.1 - 1.1e-55 189.3 0.0 1.3e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGG42705.1 - 7.5e-05 21.4 0.1 0.00015 20.4 0.1 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGG42705.1 - 0.00058 19.2 0.0 0.00097 18.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DUF148 PF02520.17 EGG42705.1 - 0.17 12.0 1.3 24 5.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 Radical_SAM PF04055.21 EGG42706.1 - 4.7e-17 62.9 0.4 1.1e-16 61.6 0.3 1.7 2 0 0 2 2 2 1 Radical SAM superfamily BATS PF06968.13 EGG42706.1 - 1.1e-12 47.9 0.0 2.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Fer4_14 PF13394.6 EGG42706.1 - 0.58 10.3 2.8 1.4 9.0 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain Aminotran_3 PF00202.21 EGG42707.1 - 1.1e-99 333.9 0.1 1.2e-99 333.8 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EGG42707.1 - 0.00027 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase TPM_phosphatase PF04536.14 EGG42708.1 - 6.5e-18 65.1 0.3 1.4e-17 64.0 0.3 1.6 1 1 0 1 1 1 1 TPM domain DUF3792 PF12670.7 EGG42708.1 - 0.0044 17.2 1.5 0.0046 17.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3792) NIF PF03031.18 EGG42708.1 - 0.16 11.7 0.0 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase LemA PF04011.12 EGG42709.1 - 7.6e-49 165.4 0.1 9.4e-49 165.1 0.1 1.1 1 0 0 1 1 1 1 LemA family ALIX_LYPXL_bnd PF13949.6 EGG42709.1 - 0.0016 17.8 1.1 0.002 17.5 1.1 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ACP_PD PF04336.12 EGG42709.1 - 0.0026 18.1 0.2 0.0036 17.7 0.2 1.3 1 0 0 1 1 1 1 Acyl carrier protein phosphodiesterase AAA_26 PF13500.6 EGG42710.1 - 1.1e-27 97.1 0.1 1.3e-27 96.9 0.1 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGG42710.1 - 0.0004 20.4 0.1 0.00059 19.9 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 EGG42710.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain zf-Tim10_DDP PF02953.15 EGG42711.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger HMG_CoA_synt_C PF08540.10 EGG42712.1 - 2.2e-32 112.8 0.1 4.4e-32 111.8 0.1 1.4 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGG42712.1 - 2.6e-30 105.5 0.2 4.3e-30 104.9 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal VHP PF02209.19 EGG42712.1 - 2.2 8.4 4.7 3.6 7.7 0.2 2.7 2 0 0 2 2 2 0 Villin headpiece domain Thioredoxin_4 PF13462.6 EGG42713.1 - 1.9e-33 116.0 0.0 2.7e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EGG42713.1 - 2.7e-17 63.2 0.1 3.5e-16 59.6 0.1 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EGG42713.1 - 2.8e-07 31.0 0.0 4.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 EGG42713.1 - 0.0046 16.7 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EGG42713.1 - 0.083 12.7 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF5314 PF17241.2 EGG42713.1 - 0.087 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Thioredoxin_8 PF13905.6 EGG42713.1 - 0.11 12.9 0.2 9 6.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like OTT_1508_deam PF14441.6 EGG42713.1 - 1.1 9.3 2.9 11 6.2 2.9 2.1 1 1 0 1 1 1 0 OTT_1508-like deaminase TackOD1 PF18551.1 EGG42714.1 - 1.1e-42 145.8 17.2 1.9e-42 145.1 17.2 1.3 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 Response_reg PF00072.24 EGG42714.1 - 1.4e-18 67.0 0.1 3.2e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain zinc-ribbons_6 PF07191.12 EGG42714.1 - 0.00058 19.8 14.8 0.076 13.0 3.5 2.7 1 1 2 3 3 3 3 zinc-ribbons HTH_24 PF13412.6 EGG42714.1 - 0.009 15.6 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding zf-Di19 PF05605.12 EGG42714.1 - 0.014 15.7 1.6 0.014 15.7 1.6 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 EGG42714.1 - 0.025 14.6 13.8 1 9.4 5.9 2.7 1 1 1 2 2 2 0 Double zinc ribbon HTH_11 PF08279.12 EGG42714.1 - 0.065 13.2 0.3 0.16 12.0 0.3 1.7 1 0 0 1 1 1 0 HTH domain HypA PF01155.19 EGG42714.1 - 0.11 12.6 18.2 0.15 12.1 2.8 3.9 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DnaJ_CXXCXGXG PF00684.19 EGG42714.1 - 0.25 11.7 12.3 17 5.8 9.3 2.8 1 1 1 2 2 2 0 DnaJ central domain Spt4 PF06093.13 EGG42714.1 - 0.77 9.9 16.4 0.63 10.2 0.2 3.5 2 1 2 4 4 4 0 Spt4/RpoE2 zinc finger Zn-ribbon_8 PF09723.10 EGG42714.1 - 2.7 8.2 22.1 3 8.0 0.1 5.5 4 2 2 6 6 6 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EGG42714.1 - 2.9 7.4 18.7 4.6 6.8 0.8 4.7 4 1 1 5 5 5 0 zinc-ribbon domain Polysacc_deac_1 PF01522.21 EGG42715.1 - 9e-16 57.9 0.0 1.5e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGG42715.1 - 5.6e-09 35.6 1.0 2.3e-05 23.8 0.0 3.3 2 1 0 2 2 2 2 Glycosyl hydrolase family 57 DUF2334 PF10096.9 EGG42715.1 - 3.2e-07 30.2 4.0 0.0029 17.3 0.3 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2334) SpaA PF17802.1 EGG42715.1 - 0.035 14.4 1.1 0.16 12.3 0.2 2.6 2 0 0 2 2 2 0 Prealbumin-like fold domain UPF0180 PF03698.13 EGG42715.1 - 0.078 13.2 1.2 7.7 6.8 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0180) Glycos_transf_2 PF00535.26 EGG42716.1 - 7.9e-33 113.7 0.0 1.3e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGG42716.1 - 1.6e-30 106.8 0.0 2.1e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGG42716.1 - 3.4e-24 85.8 0.0 3.4e-24 85.8 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 EGG42716.1 - 9.7e-11 41.0 0.2 8.6e-07 27.9 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Glyco_transf_21 PF13506.6 EGG42716.1 - 1.3e-10 41.1 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGG42716.1 - 1.4e-08 34.6 0.1 2.2e-08 33.9 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGG42716.1 - 0.02 15.4 0.0 0.058 13.9 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2070 PF09843.9 EGG42716.1 - 0.053 11.8 9.7 0.59 8.4 5.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF4191 PF13829.6 EGG42716.1 - 0.18 11.1 0.4 22 4.3 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF5345 PF17280.2 EGG42716.1 - 0.81 9.7 0.0 0.81 9.7 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DapB_N PF01113.20 EGG42717.1 - 0.0003 20.9 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 EGG42717.1 - 0.096 13.0 0.0 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EGG42717.1 - 0.14 12.9 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF21 PF01595.20 EGG42718.1 - 4.1e-50 169.9 1.0 6.5e-50 169.3 1.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EGG42718.1 - 4.8e-18 65.0 0.7 4.8e-18 65.0 0.7 2.2 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EGG42718.1 - 8e-14 51.8 2.1 4.9e-06 26.9 0.1 2.9 3 0 0 3 3 3 2 CBS domain PALP PF00291.25 EGG42719.1 - 2e-47 162.0 0.0 2.5e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Eno-Rase_FAD_bd PF07055.12 EGG42720.1 - 0.059 13.8 0.4 13 6.3 0.2 2.4 1 1 1 2 2 2 0 Enoyl reductase FAD binding domain 7TMR-HDED PF07697.11 EGG42720.1 - 0.11 12.6 0.2 0.13 12.4 0.2 1.1 1 0 0 1 1 1 0 7TM-HD extracellular DUF4441 PF14536.6 EGG42720.1 - 0.35 11.1 7.4 0.48 10.6 7.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) GIT1_C PF12205.8 EGG42721.1 - 0.0019 18.3 0.3 0.0022 18.1 0.3 1.1 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term YtxH PF12732.7 EGG42721.1 - 0.015 15.8 0.2 0.083 13.4 0.0 1.9 1 1 1 2 2 2 0 YtxH-like protein SesA PF17107.5 EGG42721.1 - 0.064 13.4 0.6 0.078 13.2 0.6 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases IFT20 PF14931.6 EGG42721.1 - 0.068 13.3 2.0 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 AIRS_C PF02769.22 EGG42722.1 - 5e-15 56.0 0.0 6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GATase_6 PF13522.6 EGG42723.1 - 3.4e-13 49.9 0.0 8.4e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGG42723.1 - 1.4e-12 47.6 0.0 2.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EGG42723.1 - 6.8e-10 38.7 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EGG42723.1 - 1.2e-05 24.3 0.0 2.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 EGG42723.1 - 0.00012 21.0 0.0 0.14 10.9 0.0 3.0 3 0 0 3 3 3 2 Glutamine amidotransferases class-II DUF3919 PF13057.6 EGG42723.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Pribosyltran_N PF13793.6 EGG42723.1 - 0.097 12.6 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Dip PF17679.1 EGG42723.1 - 0.11 12.1 0.1 0.37 10.4 0.0 1.8 3 0 0 3 3 3 0 gp37/Dip protein RQC PF09382.10 EGG42723.1 - 0.14 11.9 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 RQC domain AsnC_trans_reg PF01037.21 EGG42724.1 - 4.7e-09 36.1 0.5 5.2e-09 36.0 0.5 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain PRANC PF09372.10 EGG42724.1 - 0.0019 18.5 0.1 0.0021 18.3 0.1 1.0 1 0 0 1 1 1 1 PRANC domain Terminase_2 PF03592.16 EGG42724.1 - 0.044 14.2 1.1 0.05 14.1 1.1 1.1 1 0 0 1 1 1 0 Terminase small subunit NTP_transf_9 PF04248.12 EGG42725.1 - 1.9e-32 111.0 0.9 2.1e-32 110.9 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DUF4870 PF09685.10 EGG42726.1 - 0.0024 17.9 4.6 0.003 17.7 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) Phage_holin_3_6 PF07332.11 EGG42726.1 - 0.011 15.8 3.1 0.012 15.7 3.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Baculo_11_kDa PF06143.11 EGG42726.1 - 0.023 14.2 4.0 0.023 14.2 4.0 1.5 1 1 1 2 2 2 0 Baculovirus 11 kDa family OSTMP1 PF09777.9 EGG42726.1 - 0.024 14.0 0.9 0.022 14.1 0.9 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF996 PF06195.13 EGG42726.1 - 0.025 14.8 6.8 0.03 14.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Arteri_Gl PF00951.18 EGG42726.1 - 0.037 13.8 3.5 0.044 13.6 3.5 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Deltameth_res PF16020.5 EGG42726.1 - 0.12 12.3 1.4 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 Deltamethrin resistance DUF2207 PF09972.9 EGG42726.1 - 0.13 11.0 4.9 0.14 10.9 4.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VIT1 PF01988.19 EGG42726.1 - 0.53 10.1 3.2 0.54 10.1 3.2 1.1 1 0 0 1 1 1 0 VIT family Wzy_C PF04932.15 EGG42726.1 - 0.6 9.7 4.7 0.67 9.6 4.7 1.1 1 0 0 1 1 1 0 O-Antigen ligase YrhC PF14143.6 EGG42726.1 - 1.2 9.2 7.7 2.8 8.1 5.0 1.9 1 1 1 2 2 2 0 YrhC-like protein DUF2721 PF11026.8 EGG42726.1 - 1.3 8.9 8.7 1.8 8.5 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2367 PF10164.9 EGG42726.1 - 1.8 9.1 4.2 1.3 9.6 3.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) TMEM171 PF15471.6 EGG42726.1 - 3.5 6.5 9.0 0.31 10.0 2.7 1.9 1 1 1 2 2 2 0 Transmembrane protein family 171 LapA_dom PF06305.11 EGG42726.1 - 9.4 6.1 10.0 0.96 9.3 2.1 2.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Pentapeptide PF00805.22 EGG42727.1 - 2.2e-34 116.6 12.3 7.3e-11 41.5 0.1 4.4 1 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGG42727.1 - 5e-16 58.6 0.0 1.3e-08 34.8 0.0 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGG42727.1 - 3.4e-13 49.5 0.6 9.7e-05 22.5 0.2 4.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) zf-C6H2 PF15801.5 EGG42728.1 - 0.012 15.9 7.6 0.013 15.8 2.4 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-C2HC_2 PF13913.6 EGG42728.1 - 0.052 13.5 7.2 1.5 8.8 1.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 EGG42728.1 - 0.12 12.3 3.9 0.76 9.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PLATZ PF04640.14 EGG42728.1 - 0.47 11.1 9.5 0.79 10.4 4.2 2.0 2 0 0 2 2 2 0 PLATZ transcription factor RIG-I_C-RD PF11648.8 EGG42728.1 - 0.56 10.5 6.6 0.92 9.8 6.6 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I HypA PF01155.19 EGG42728.1 - 1.3 9.1 7.4 48 4.0 7.4 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 EGG42728.1 - 1.3 9.1 10.4 3.7 7.6 2.7 2.7 2 1 0 2 2 2 0 Adenylate kinase, active site lid C1_1 PF00130.22 EGG42728.1 - 4.9 7.1 9.6 1.1 9.2 2.2 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cript PF10235.9 EGG42728.1 - 5.9 7.5 11.9 1.3 9.7 4.0 2.2 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT NOB1_Zn_bind PF08772.11 EGG42728.1 - 7.6 6.8 11.2 19 5.5 3.9 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF5300 PF17224.3 EGG42729.1 - 0.00015 22.0 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5300) SAICAR_synt PF01259.18 EGG42730.1 - 3.8e-43 147.9 0.0 4.6e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase HTH_20 PF12840.7 EGG42731.1 - 1.9e-08 34.2 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EGG42731.1 - 3.1e-07 30.2 0.4 2.4e-06 27.3 0.4 2.2 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.10 EGG42731.1 - 1.6e-06 27.9 0.3 3.5e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain FUR PF01475.19 EGG42731.1 - 0.00012 22.2 0.3 0.00027 21.0 0.3 1.7 1 1 0 1 1 1 1 Ferric uptake regulator family HU-DNA_bdg PF14848.6 EGG42731.1 - 0.0073 16.3 1.0 0.023 14.7 0.4 1.9 1 1 1 2 2 2 1 DNA-binding domain Replic_Relax PF13814.6 EGG42731.1 - 0.014 15.4 0.1 0.035 14.2 0.0 1.7 2 0 0 2 2 2 0 Replication-relaxation Type2_restr_D3 PF16902.5 EGG42731.1 - 0.026 14.5 0.3 0.059 13.3 0.3 1.6 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain HTH_11 PF08279.12 EGG42731.1 - 0.028 14.4 0.8 0.35 10.9 0.8 2.3 1 1 0 1 1 1 0 HTH domain Putative_PNPOx PF01243.20 EGG42732.1 - 1e-15 57.7 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EGG42732.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.3 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase RcnB PF11776.8 EGG42732.1 - 0.077 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator GATase_5 PF13507.6 EGG42733.1 - 5.2e-37 127.4 0.0 1.6e-36 125.8 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EGG42733.1 - 7.2e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGG42733.1 - 1.1e-08 34.9 0.0 4e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EGG42733.1 - 6.2e-08 32.6 0.0 9.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 EGG42733.1 - 0.0011 18.8 0.2 0.0023 17.7 0.2 1.6 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 EGG42733.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 SNO glutamine amidotransferase family PRESAN PF09687.10 EGG42734.1 - 0.033 14.8 0.0 0.071 13.7 0.0 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal MscL PF01741.18 EGG42736.1 - 6.3e-23 81.4 4.2 7.3e-23 81.2 4.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Plasmodium_Vir PF05795.11 EGG42736.1 - 0.0014 18.1 1.0 0.0017 17.8 1.0 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Reticulon PF02453.17 EGG42736.1 - 0.0028 17.6 0.6 0.0036 17.3 0.6 1.1 1 0 0 1 1 1 1 Reticulon FtsX PF02687.21 EGG42736.1 - 0.03 14.8 5.3 0.047 14.2 5.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family DUF1449 PF07290.11 EGG42736.1 - 0.057 13.1 1.4 0.058 13.0 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1449) Intg_mem_TP0381 PF09529.10 EGG42736.1 - 0.2 11.2 3.3 0.074 12.6 0.6 1.6 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) DUF4834 PF16118.5 EGG42736.1 - 0.31 12.0 2.8 1.1 10.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AsnC_trans_reg PF01037.21 EGG42737.1 - 4.7e-10 39.3 0.1 5.4e-10 39.1 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain DUF4795 PF16043.5 EGG42737.1 - 0.025 14.2 1.0 0.025 14.2 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Flu_M1_C PF08289.11 EGG42737.1 - 0.036 14.3 0.2 2.8 8.2 0.0 2.0 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain NEXCaM_BD PF16644.5 EGG42737.1 - 0.071 13.4 0.3 0.093 13.0 0.2 1.3 1 1 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin GLTP PF08718.11 EGG42737.1 - 0.077 13.3 0.3 0.085 13.1 0.3 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) NapD PF03927.13 EGG42737.1 - 0.078 13.0 0.5 0.11 12.6 0.5 1.2 1 0 0 1 1 1 0 NapD protein DUF4064 PF13273.6 EGG42741.1 - 0.00018 21.7 1.3 0.00022 21.4 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF2207 PF09972.9 EGG42741.1 - 0.024 13.4 0.2 0.027 13.2 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3185 PF11381.8 EGG42741.1 - 0.2 11.7 6.5 2.7 8.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Cortexin PF11057.8 EGG42741.1 - 0.41 10.5 0.1 0.41 10.5 0.1 2.0 2 0 0 2 2 2 0 Cortexin of kidney SP_C-Propep PF08999.10 EGG42741.1 - 6.8 6.6 7.6 1.3 8.9 0.8 2.0 1 1 1 2 2 2 0 Surfactant protein C, N terminal propeptide TrbC PF04956.13 EGG42741.1 - 9.4 6.5 9.3 0.84 9.9 0.6 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family Polyketide_cyc2 PF10604.9 EGG42742.1 - 1.1e-14 55.0 0.0 1.2e-14 54.8 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GAS PF13851.6 EGG42743.1 - 6.7e-05 22.3 30.9 0.00053 19.4 5.3 3.0 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EGG42743.1 - 0.00017 21.6 38.0 0.00028 20.9 5.9 3.7 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EGG42743.1 - 0.0014 17.6 32.8 0.096 11.6 6.4 3.1 2 1 0 2 2 2 2 Spc7 kinetochore protein DUF948 PF06103.11 EGG42743.1 - 0.0055 16.9 24.2 0.67 10.3 1.2 5.7 4 2 1 5 5 5 1 Bacterial protein of unknown function (DUF948) HOOK PF05622.12 EGG42743.1 - 0.009 14.2 35.3 0.2 9.8 8.9 2.3 1 1 0 2 2 2 2 HOOK protein APG6_N PF17675.1 EGG42743.1 - 0.014 16.0 4.9 0.014 16.0 4.9 3.0 3 1 0 3 3 2 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 EGG42743.1 - 0.02 15.0 1.8 0.02 15.0 1.8 5.2 1 1 5 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus BEN PF10523.9 EGG42743.1 - 0.032 14.5 1.4 0.11 12.7 0.5 2.5 2 0 0 2 2 2 0 BEN domain Rx_N PF18052.1 EGG42743.1 - 0.051 13.9 0.7 0.051 13.9 0.7 4.4 3 2 2 5 5 5 0 Rx N-terminal domain HemX PF04375.14 EGG42743.1 - 0.053 12.8 18.6 0.25 10.6 8.5 2.9 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 EGG42743.1 - 0.096 12.0 28.7 0.57 9.4 3.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) AFP_2 PF18815.1 EGG42743.1 - 0.1 12.9 0.9 12 6.3 0.2 3.4 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat DUF4351 PF14261.6 EGG42743.1 - 0.2 11.7 11.2 10 6.2 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4351) DHR10 PF18595.1 EGG42743.1 - 0.33 11.0 28.4 0.072 13.2 9.2 4.0 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain MscS_porin PF12795.7 EGG42743.1 - 0.46 10.0 25.2 1 8.8 14.4 2.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.7 EGG42743.1 - 0.68 10.1 24.9 0.16 12.1 9.6 3.2 2 1 0 2 2 2 0 Tropomyosin like FapA PF03961.13 EGG42743.1 - 0.69 8.5 36.9 0.018 13.6 12.4 3.1 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF4407 PF14362.6 EGG42743.1 - 0.79 9.0 13.1 0.16 11.3 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EGG42743.1 - 0.93 10.0 38.5 0.96 10.0 1.9 6.3 3 3 3 6 6 6 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EGG42743.1 - 0.94 9.9 24.0 1.4 9.4 3.5 5.2 2 2 4 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4349 PF14257.6 EGG42743.1 - 1.1 8.7 10.9 7.8 5.9 5.2 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4349) Phage_GPO PF05929.11 EGG42743.1 - 1.1 8.8 17.6 0.68 9.5 6.2 2.5 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase XhlA PF10779.9 EGG42743.1 - 1.8 8.8 34.8 0.28 11.4 7.4 5.2 3 2 2 5 5 5 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 EGG42743.1 - 2 8.5 27.9 8.9 6.4 0.6 3.8 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 EGG42743.1 - 2.3 8.4 11.1 1.5 9.0 0.1 3.3 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Snapin_Pallidin PF14712.6 EGG42743.1 - 2.5 8.6 35.6 0.12 12.9 5.3 5.1 2 1 3 6 6 6 0 Snapin/Pallidin T3SSipB PF16535.5 EGG42743.1 - 3.1 8.3 19.1 4.2 7.8 6.1 4.1 3 2 2 5 5 5 0 Type III cell invasion protein SipB DUF1664 PF07889.12 EGG42743.1 - 3.3 7.8 34.4 0.34 10.9 7.9 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EGG42743.1 - 5.3 7.3 35.6 0.52 10.6 6.9 4.4 3 1 3 6 6 6 0 Seryl-tRNA synthetase N-terminal domain Prok-JAB PF14464.6 EGG42744.1 - 2.4e-12 46.6 0.0 3.6e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-NADH-PPase PF09297.11 EGG42745.1 - 0.0036 16.9 3.1 0.045 13.4 0.7 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Peptidase_C74 PF12387.8 EGG42745.1 - 0.031 13.8 1.5 0.041 13.4 1.5 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Zn_ribbon_recom PF13408.6 EGG42745.1 - 0.11 13.0 5.2 1 9.9 5.2 2.2 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 EGG42745.1 - 0.24 11.0 1.5 0.51 10.0 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 EGG42745.1 - 0.48 10.6 4.0 2.4 8.3 4.0 1.9 1 1 0 1 1 1 0 Zinc ribbon domain TFIIS_C PF01096.18 EGG42745.1 - 0.67 9.9 3.2 15 5.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) BPD_transp_1 PF00528.22 EGG42747.1 - 5.7e-27 94.6 9.1 5.7e-27 94.6 9.1 2.3 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EGG42747.1 - 0.017 15.1 0.2 0.017 15.1 0.2 2.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EGG42748.1 - 1.7e-37 129.0 17.8 1.7e-37 129.0 17.8 1.8 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component DUF3481 PF11980.8 EGG42748.1 - 3.1 7.6 7.3 8.4 6.2 0.2 2.7 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein DUF3290 PF11694.8 EGG42750.1 - 0.11 12.5 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) CarboxypepD_reg PF13620.6 EGG42751.1 - 2.6e-07 30.8 0.9 5.3e-07 29.8 0.9 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 EGG42751.1 - 5.3e-05 23.1 0.8 5.3e-05 23.1 0.8 2.2 2 1 0 2 2 2 1 Bacterial Ig-like domain (group 1) MetallophosN PF16371.5 EGG42751.1 - 0.00029 21.0 0.2 0.00065 19.9 0.2 1.6 1 0 0 1 1 1 1 N terminal of Calcineurin-like phosphoesterase CarbopepD_reg_2 PF13715.6 EGG42751.1 - 0.00039 20.4 1.1 0.0012 18.8 1.1 1.9 1 0 0 1 1 1 1 CarboxypepD_reg-like domain DUF3450 PF11932.8 EGG42751.1 - 0.011 15.0 4.4 0.028 13.7 4.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SdrD_B PF17210.3 EGG42751.1 - 0.044 14.0 0.5 0.044 14.0 0.5 1.8 2 0 0 2 2 2 0 SdrD B-like domain Big_6 PF17936.1 EGG42751.1 - 0.094 13.0 0.4 0.29 11.5 0.4 1.8 1 0 0 1 1 1 0 Bacterial Ig domain Snapin_Pallidin PF14712.6 EGG42751.1 - 0.2 12.1 2.2 1.4 9.4 0.0 2.3 1 1 1 2 2 2 0 Snapin/Pallidin FlgD_ig PF13860.6 EGG42752.1 - 0.039 13.8 0.5 0.79 9.6 0.2 2.6 2 1 0 2 2 2 0 FlgD Ig-like domain DUF5400 PF17379.2 EGG42752.1 - 0.12 12.9 0.3 0.12 12.9 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5400) SNF2_N PF00176.23 EGG42754.1 - 4.1e-38 131.0 0.0 6e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG42754.1 - 4.1e-13 49.6 0.6 2.1e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG42754.1 - 4.5e-09 36.5 0.1 4.5e-09 36.5 0.1 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG42754.1 - 3.6e-06 26.8 0.2 1.1e-05 25.3 0.0 1.9 2 1 1 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGG42754.1 - 0.04 13.1 0.1 0.081 12.1 0.1 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HTH_5 PF01022.20 EGG42755.1 - 0.0025 17.6 1.1 0.0093 15.8 0.3 2.3 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 EGG42755.1 - 0.011 15.8 0.3 0.032 14.4 0.2 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain MRP-L20 PF12824.7 EGG42755.1 - 0.015 15.5 1.6 0.021 15.0 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Baculo_LEF-11 PF06385.12 EGG42755.1 - 0.021 15.3 1.0 2.7 8.5 0.1 2.3 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Fe_dep_repress PF01325.19 EGG42755.1 - 0.043 14.0 0.5 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 EGG42755.1 - 0.079 12.9 0.2 0.53 10.2 0.1 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EGG42755.1 - 0.17 11.9 0.0 1.5 8.9 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain HSP20 PF00011.21 EGG42756.1 - 1.3e-23 83.1 2.0 1.7e-23 82.7 2.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG42756.1 - 4.3e-06 26.2 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EGG42756.1 - 0.00013 22.9 0.9 0.00022 22.2 0.9 1.3 1 0 0 1 1 1 1 CS domain FKBP26_C PF18046.1 EGG42756.1 - 0.0012 18.8 0.7 1.6 8.9 0.1 2.5 2 0 0 2 2 2 2 FKBP26_C-terminal PIH1_CS PF18201.1 EGG42756.1 - 0.017 15.5 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 PIH1 CS-like domain OsmC PF02566.19 EGG42757.1 - 2e-17 63.5 0.0 3.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein Sod_Fe_N PF00081.22 EGG42758.1 - 1.1e-20 73.9 0.2 1.2e-20 73.8 0.2 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 EGG42759.1 - 3e-31 107.6 2.1 3.4e-31 107.4 2.1 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Telethonin PF09470.10 EGG42759.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Telethonin protein TBP PF00352.21 EGG42761.1 - 6.7e-55 183.0 0.1 3.1e-27 94.3 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGG42761.1 - 6e-07 29.5 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) SHOCT PF09851.9 EGG42762.1 - 6.3e-11 41.6 1.4 1.1e-10 40.8 1.4 1.5 1 0 0 1 1 1 1 Short C-terminal domain Popeye PF04831.13 EGG42762.1 - 0.0069 16.6 0.0 0.0084 16.3 0.0 1.1 1 0 0 1 1 1 1 Popeye protein conserved region TauE PF01925.19 EGG42762.1 - 0.028 14.0 0.0 0.029 14.0 0.0 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE GvpG PF05120.12 EGG42762.1 - 0.058 13.4 0.7 0.099 12.7 0.7 1.5 1 1 0 1 1 1 0 Gas vesicle protein G VbhA PF18495.1 EGG42762.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Antitoxin VbhA DUF1707 PF08044.11 EGG42762.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) FAD_binding_4 PF01565.23 EGG42763.1 - 9.9e-33 112.8 0.0 1.7e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 EGG42763.1 - 3.3e-29 102.3 0.0 5.8e-29 101.5 0.0 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain UPF0113_N PF17833.1 EGG42763.1 - 4.7 7.8 7.0 1 10.0 0.4 3.1 4 0 0 4 4 4 0 UPF0113 Pre-PUA domain Transglut_C PF00927.22 EGG42765.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain HD PF01966.22 EGG42766.1 - 0.003 17.8 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 EGG42766.1 - 0.039 13.7 1.5 0.05 13.3 0.4 1.7 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase DUF1091 PF06477.13 EGG42766.1 - 0.066 13.7 0.1 0.19 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) DnaJ PF00226.31 EGG42768.1 - 1.1e-21 76.6 7.2 1.1e-21 76.6 7.2 2.1 2 1 0 2 2 2 1 DnaJ domain SUIM_assoc PF16619.5 EGG42768.1 - 0.12 12.4 1.3 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF262 PF03235.14 EGG42768.1 - 1.9 8.6 12.4 2.7 8.1 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF262 DPM3 PF08285.11 EGG42768.1 - 7.1 6.9 5.4 8.8 6.6 0.9 2.9 2 2 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HTH_24 PF13412.6 EGG42769.1 - 2.3e-12 46.3 2.3 2.3e-12 46.3 2.3 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EGG42769.1 - 3.1e-12 46.1 1.3 4.8e-12 45.5 1.3 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 EGG42769.1 - 1.6e-11 44.0 0.1 2.5e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 EGG42769.1 - 4.3e-05 23.4 0.4 4.3e-05 23.4 0.4 1.8 2 0 0 2 2 2 1 HTH domain HTH_Crp_2 PF13545.6 EGG42769.1 - 0.0006 19.7 0.2 0.0012 18.8 0.2 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_50 PF18024.1 EGG42769.1 - 0.0013 18.3 0.1 0.0045 16.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EGG42769.1 - 0.0074 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_10 PF04967.12 EGG42769.1 - 0.0082 15.9 0.3 0.02 14.7 0.3 1.7 1 0 0 1 1 1 1 HTH DNA binding domain HTH_20 PF12840.7 EGG42769.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.13 EGG42769.1 - 0.019 15.2 0.1 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 NUMOD1 domain DDRGK PF09756.9 EGG42769.1 - 0.021 14.4 0.7 0.045 13.3 0.2 1.7 1 1 1 2 2 2 0 DDRGK domain GntR PF00392.21 EGG42769.1 - 0.049 13.3 0.2 0.081 12.6 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR PF01047.22 EGG42769.1 - 0.053 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 MarR family HTH_3 PF01381.22 EGG42769.1 - 0.27 11.3 2.3 0.74 9.9 0.1 2.7 3 1 0 3 3 3 0 Helix-turn-helix MazG-like PF12643.7 EGG42769.1 - 0.63 10.3 6.1 1.4 9.2 0.5 2.5 3 0 0 3 3 3 0 MazG-like family TPR_1 PF00515.28 EGG42770.1 - 2.4e-16 58.7 0.0 3.4e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42770.1 - 1.1e-14 53.3 0.0 9.8e-08 31.6 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG42770.1 - 1.6e-12 46.6 0.0 3.7e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG42770.1 - 9.4e-12 44.4 0.0 0.00012 21.6 0.0 2.1 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.6 EGG42770.1 - 2.3e-10 40.9 0.0 2.6e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG42770.1 - 7.9e-10 38.1 0.0 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG42770.1 - 1.7e-08 34.5 0.0 2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42770.1 - 3.6e-08 33.8 0.0 3.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG42770.1 - 2.6e-07 30.8 0.1 0.00059 20.1 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG42770.1 - 8.4e-07 29.3 0.0 0.032 15.0 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG42770.1 - 2e-06 27.8 0.1 7.7e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG42770.1 - 0.00011 22.4 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGG42770.1 - 0.0013 18.5 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 EGG42770.1 - 0.0055 16.9 0.0 0.54 10.5 0.0 2.1 1 1 1 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 EGG42770.1 - 0.016 15.2 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 EGG42770.1 - 0.03 13.2 0.0 0.034 13.1 0.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 EGG42770.1 - 0.031 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit DUF3856 PF12968.7 EGG42770.1 - 0.047 13.8 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 EGG42770.1 - 0.055 12.9 1.1 7.8 6.0 1.2 2.4 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 EGG42770.1 - 0.056 14.1 0.0 0.97 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42770.1 - 0.069 13.2 0.1 0.37 10.9 0.0 2.0 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EGG42770.1 - 0.096 13.0 0.1 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 PPR repeat TFIIB PF00382.19 EGG42771.1 - 9.2e-31 105.7 6.1 4.4e-16 58.7 0.4 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG42771.1 - 3.8e-10 39.1 1.1 6.2e-10 38.4 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EGG42771.1 - 0.0022 18.1 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 EGG42771.1 - 0.0045 16.5 0.0 0.45 10.1 0.0 3.5 3 1 1 4 4 4 1 Sigma-70, region 4 RPW8 PF05659.11 EGG42771.1 - 0.0064 16.2 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cyclin_N PF00134.23 EGG42771.1 - 0.0066 16.2 0.8 0.061 13.1 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain HTH_11 PF08279.12 EGG42771.1 - 0.0084 16.0 1.1 0.092 12.7 0.0 2.7 3 0 0 3 3 3 1 HTH domain HTH_AsnC-type PF13404.6 EGG42771.1 - 0.0093 15.8 0.0 0.24 11.3 0.0 2.8 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain RB_B PF01857.20 EGG42771.1 - 0.011 15.8 0.1 0.02 14.9 0.1 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 EGG42771.1 - 0.043 13.3 2.7 0.22 11.0 2.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Sigma70_r4_2 PF08281.12 EGG42771.1 - 0.19 11.4 1.5 5.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 zf-NADH-PPase PF09297.11 EGG42771.1 - 0.25 11.1 1.5 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 EGG42771.1 - 1.2 9.0 4.1 0.7 9.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Usp PF00582.26 EGG42772.1 - 5.1e-28 98.3 0.0 6.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family GARS_N PF02844.15 EGG42772.1 - 0.0011 19.8 0.1 0.0018 19.0 0.1 1.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain SIM_C PF06621.12 EGG42772.1 - 0.054 13.5 0.0 0.059 13.4 0.0 1.0 1 0 0 1 1 1 0 Single-minded protein C-terminus CHIPS PF11434.8 EGG42772.1 - 0.064 13.1 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Peptidase_M15_4 PF13539.6 EGG42772.1 - 0.13 12.8 0.1 0.29 11.7 0.1 1.6 1 1 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF1415 PF07209.12 EGG42772.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) TPR_1 PF00515.28 EGG42773.1 - 1.2e-23 81.9 9.7 6.5e-07 28.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG42773.1 - 1.7e-21 74.6 6.0 4.3e-05 23.3 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG42773.1 - 1.4e-14 53.5 6.0 0.00032 20.3 0.1 4.1 1 1 3 4 4 4 4 TPR repeat TPR_8 PF13181.6 EGG42773.1 - 1.6e-14 52.8 6.3 6.4e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG42773.1 - 1.8e-12 47.0 0.0 0.029 15.2 0.0 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGG42773.1 - 5.8e-12 46.1 0.0 3.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG42773.1 - 1.1e-11 44.2 1.6 0.0094 16.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG42773.1 - 3.7e-11 43.2 1.7 2e-05 24.8 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG42773.1 - 1.4e-10 40.4 0.6 0.0074 16.2 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGG42773.1 - 1.6e-10 41.0 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42773.1 - 2.6e-09 37.5 1.9 7.6e-05 23.1 0.2 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42773.1 - 8e-08 32.2 0.5 0.43 10.7 0.0 4.2 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EGG42773.1 - 1.2e-07 31.8 0.9 1.2e-05 25.5 0.3 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGG42773.1 - 1.2e-06 28.2 0.1 1.3 9.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGG42773.1 - 8.3e-06 25.7 1.1 0.00053 19.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG42773.1 - 1.6e-05 25.2 1.2 0.42 11.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 EGG42773.1 - 8.9e-05 22.6 0.0 1.3 9.1 0.0 3.3 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) MIT PF04212.18 EGG42773.1 - 0.00089 19.3 2.7 0.8 9.8 0.1 4.0 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain CODH_A_N PF18537.1 EGG42773.1 - 0.0059 16.6 0.0 0.095 12.7 0.0 2.3 2 0 0 2 2 2 1 Carbon monoxide dehydrogenase subunit alpha N-terminal domain PPR PF01535.20 EGG42773.1 - 0.066 13.5 0.3 8.9 6.8 0.1 3.1 4 0 0 4 4 3 0 PPR repeat OTT_1508_deam PF14441.6 EGG42774.1 - 0.0015 18.5 0.1 0.002 18.1 0.1 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-C2H2_11 PF16622.5 EGG42774.1 - 0.044 13.5 0.2 0.059 13.1 0.2 1.2 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGG42774.1 - 0.083 13.2 3.5 0.37 11.1 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Radical_SAM PF04055.21 EGG42775.1 - 3.4e-18 66.6 0.0 6.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EGG42775.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain TMEM51 PF15345.6 EGG42776.1 - 8.5e-06 25.8 0.1 9.4e-06 25.6 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 Oxidored_q3 PF00499.20 EGG42776.1 - 0.0025 17.5 0.1 0.0032 17.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Tetraspanin PF00335.20 EGG42776.1 - 0.0028 17.4 0.3 0.0034 17.1 0.3 1.0 1 0 0 1 1 1 1 Tetraspanin family MnhB PF04039.13 EGG42776.1 - 0.0099 16.2 0.2 0.17 12.2 0.0 2.0 2 0 0 2 2 2 1 Domain related to MnhB subunit of Na+/H+ antiporter 7tm_3 PF00003.22 EGG42776.1 - 0.085 12.6 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF2207 PF09972.9 EGG42776.1 - 0.1 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OSTbeta PF15048.6 EGG42776.1 - 0.1 12.8 0.2 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF202 PF02656.15 EGG42776.1 - 0.22 12.0 0.8 0.5 10.9 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF872 PF05915.12 EGG42776.1 - 1.1 9.4 4.3 11 6.2 0.1 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3899 PF13038.6 EGG42776.1 - 1.1 9.8 4.0 18 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Syndecan PF01034.20 EGG42776.1 - 1.5 8.7 4.3 33 4.5 2.9 2.2 2 0 0 2 2 2 0 Syndecan domain DUF4064 PF13273.6 EGG42776.1 - 2.3 8.5 8.8 34 4.8 8.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Gram_pos_anchor PF00746.21 EGG42776.1 - 6.2 6.9 9.5 3.3 7.7 1.5 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TrkH PF02386.16 EGG42777.1 - 7.8e-08 31.2 0.3 8.3e-08 31.1 0.3 1.0 1 0 0 1 1 1 1 Cation transport protein CBS PF00571.28 EGG42778.1 - 6.1e-20 71.4 4.1 3.2e-10 40.3 0.2 2.4 2 0 0 2 2 2 2 CBS domain TrkH PF02386.16 EGG42778.1 - 9.6e-17 60.6 12.6 8.4e-09 34.4 0.1 2.4 2 0 0 2 2 2 2 Cation transport protein T3RM_EcoP15I_C PF18273.1 EGG42778.1 - 0.14 12.4 1.5 0.24 11.7 0.2 2.0 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain zf-ribbon_3 PF13248.6 EGG42779.1 - 0.013 14.9 2.6 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 EGG42779.1 - 0.017 15.2 1.0 0.025 14.7 1.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-ISL3 PF14690.6 EGG42779.1 - 0.021 15.5 0.6 2.6 8.8 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 C1_1 PF00130.22 EGG42779.1 - 0.14 12.0 4.6 0.24 11.3 4.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 EGG42779.1 - 0.15 11.9 8.6 0.79 9.6 8.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain HSCB_C PF07743.13 EGG42781.1 - 0.02 15.3 0.8 0.096 13.2 0.2 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Xylo_C PF12529.8 EGG42782.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Xylosyltransferase C terminal CagY_M PF07337.11 EGG42782.1 - 2 8.1 4.3 8 6.2 0.1 3.1 3 0 0 3 3 3 0 DC-EC Repeat COG6 PF06419.11 EGG42783.1 - 0.00051 18.4 3.9 0.00055 18.3 3.9 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 CLZ PF16526.5 EGG42783.1 - 0.0025 18.1 4.8 0.041 14.3 0.9 2.1 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PI3K_P85_iSH2 PF16454.5 EGG42783.1 - 0.003 17.2 6.3 0.004 16.8 6.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Flagellar_rod PF05149.12 EGG42783.1 - 0.005 16.3 4.9 0.0056 16.2 4.9 1.0 1 0 0 1 1 1 1 Paraflagellar rod protein DUF724 PF05266.14 EGG42783.1 - 0.0057 16.5 5.6 0.0068 16.3 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF4472 PF14739.6 EGG42783.1 - 0.0096 16.6 4.1 0.011 16.5 4.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) GAS PF13851.6 EGG42783.1 - 0.011 15.0 6.3 0.015 14.7 6.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.6 EGG42783.1 - 0.013 15.9 3.9 0.62 10.5 0.2 2.0 1 1 1 2 2 2 0 Snapin/Pallidin DUF4200 PF13863.6 EGG42783.1 - 0.019 15.4 6.2 0.028 14.8 6.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 EGG42783.1 - 0.023 13.9 3.6 0.024 13.9 3.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein CENP-H PF05837.12 EGG42783.1 - 0.03 14.7 3.4 0.036 14.5 3.4 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Mt_ATP-synt_D PF05873.12 EGG42783.1 - 0.031 14.1 1.7 0.034 14.0 1.7 1.0 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) ABC_tran_CTD PF16326.5 EGG42783.1 - 0.032 14.5 5.8 0.82 10.0 5.8 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain SlyX PF04102.12 EGG42783.1 - 0.032 14.9 3.5 0.065 13.9 0.5 2.0 1 1 1 2 2 2 0 SlyX ADIP PF11559.8 EGG42783.1 - 0.034 14.2 5.7 0.043 13.9 5.7 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EGG42783.1 - 0.04 14.5 6.8 0.05 14.1 6.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 EGG42783.1 - 0.043 13.9 3.6 0.06 13.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 EGG42783.1 - 0.049 13.1 3.2 0.062 12.8 3.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF16 PF01519.16 EGG42783.1 - 0.066 13.7 3.2 0.076 13.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 EGG42783.1 - 0.075 12.6 2.7 0.094 12.3 2.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region BLOC1_2 PF10046.9 EGG42783.1 - 0.08 13.3 3.7 0.17 12.2 0.6 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup88 PF10168.9 EGG42783.1 - 0.095 10.5 6.6 0.11 10.3 6.6 1.0 1 0 0 1 1 1 0 Nuclear pore component FapA PF03961.13 EGG42783.1 - 0.12 11.0 6.3 0.13 10.8 6.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 EGG42783.1 - 0.14 12.4 6.6 0.31 11.3 6.6 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 EGG42783.1 - 0.16 12.1 7.1 0.2 11.7 7.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin PF02996.17 EGG42783.1 - 0.2 11.5 4.4 0.15 12.0 1.9 1.8 1 1 1 2 2 2 0 Prefoldin subunit CCDC-167 PF15188.6 EGG42783.1 - 0.22 11.9 6.6 0.31 11.4 6.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 EGG42783.1 - 0.27 11.2 8.2 0.21 11.6 2.7 1.9 1 1 2 3 3 3 0 Prefoldin subunit DivIC PF04977.15 EGG42783.1 - 0.34 10.7 7.4 1.6 8.6 1.6 2.1 1 1 1 2 2 2 0 Septum formation initiator EMP24_GP25L PF01105.24 EGG42783.1 - 0.38 10.7 4.3 0.99 9.3 4.3 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.6 EGG42783.1 - 0.51 10.8 5.1 1.3 9.5 1.0 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 EGG42783.1 - 0.53 10.5 9.7 4.7 7.5 9.6 2.0 1 1 0 1 1 1 0 Haemolysin XhlA FlaC_arch PF05377.11 EGG42783.1 - 0.6 10.6 6.1 6.8 7.2 6.1 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF3781 PF12636.7 EGG42784.1 - 0.0094 15.8 0.6 0.015 15.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3781) VitK2_biosynth PF02621.14 EGG42786.1 - 4e-71 239.6 0.0 4.5e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis Imm26 PF15428.6 EGG42786.1 - 0.04 14.1 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 26 Spore_III_AB PF09548.10 EGG42786.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SCAB_CC PF16712.5 EGG42786.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein YhfZ_C PF14503.6 EGG42786.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain SIS PF01380.22 EGG42788.1 - 2e-05 24.4 0.0 3.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 SIS domain GTP_EFTU PF00009.27 EGG42789.1 - 3.6e-60 202.9 0.6 5.8e-60 202.2 0.6 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGG42789.1 - 7.4e-22 77.2 0.0 2.4e-21 75.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EGG42789.1 - 1.2e-20 73.4 0.0 6.1e-20 71.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 EGG42789.1 - 1.3e-20 73.3 0.7 3.2e-20 72.0 0.7 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGG42789.1 - 2.3e-12 47.1 0.1 8.7e-12 45.3 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG42789.1 - 0.027 14.5 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RF3_C PF16658.5 EGG42789.1 - 0.042 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain DUF4393 PF14337.6 EGG42789.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Penicillinase_R PF03965.16 EGG42792.1 - 0.0012 19.2 0.1 0.002 18.5 0.1 1.4 1 0 0 1 1 1 1 Penicillinase repressor AAA_assoc_C PF09821.9 EGG42792.1 - 0.085 13.4 0.1 0.3 11.6 0.0 1.9 1 1 1 2 2 2 0 C-terminal AAA-associated domain Kelch_1 PF01344.25 EGG42793.1 - 0.16 11.6 0.4 9.7 5.9 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 EGG42793.1 - 0.17 12.0 0.7 0.68 10.0 0.0 2.1 3 0 0 3 3 3 0 Galactose oxidase, central domain CSTF2_hinge PF14327.6 EGG42794.1 - 0.031 14.7 0.6 0.039 14.4 0.5 1.4 1 1 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF247 PF03140.15 EGG42795.1 - 0.055 12.7 0.1 0.061 12.5 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function RPA_interact_C PF14768.6 EGG42796.1 - 0.031 14.9 0.6 5 7.8 0.0 2.1 2 0 0 2 2 2 0 Replication protein A interacting C-terminal TF_Zn_Ribbon PF08271.12 EGG42796.1 - 0.12 11.9 2.0 0.18 11.4 2.0 1.4 1 1 0 1 1 1 0 TFIIB zinc-binding Ycf66_N PF07444.11 EGG42797.1 - 7e-06 26.1 0.1 0.0026 17.9 0.0 2.2 2 0 0 2 2 2 2 Ycf66 protein N-terminus FixQ PF05545.11 EGG42797.1 - 0.13 12.2 4.2 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Gram_pos_anchor PF00746.21 EGG42797.1 - 3.3 7.7 4.8 21 5.1 0.5 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Nefa_Nip30_N PF10187.9 EGG42799.1 - 0.021 15.1 0.1 0.036 14.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF5615 PF18480.1 EGG42800.1 - 3.3e-07 30.0 0.1 4.8e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5615) Mut7-C PF01927.16 EGG42800.1 - 0.0051 16.9 0.0 0.0052 16.9 0.0 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain CBS PF00571.28 EGG42803.1 - 1.6e-18 66.9 5.2 2.3e-11 44.0 0.1 2.8 3 0 0 3 3 3 2 CBS domain TrkH PF02386.16 EGG42803.1 - 5.6e-15 54.8 32.6 2.1e-07 29.8 11.4 3.5 1 1 1 2 2 2 2 Cation transport protein DNase-RNase PF02577.14 EGG42804.1 - 1.8e-07 30.8 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease Nup188_C PF18378.1 EGG42805.1 - 0.029 13.2 0.1 0.029 13.2 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain TFB6 PF17110.5 EGG42805.1 - 0.075 12.8 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH HD_4 PF13328.6 EGG42807.1 - 1.3e-15 57.4 0.0 1.7e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 HD domain AalphaY_MDB PF04611.12 EGG42807.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region zf-trcl PF13451.6 EGG42809.1 - 0.017 15.0 0.5 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-FPG_IleRS PF06827.14 EGG42809.1 - 0.062 13.2 1.3 0.95 9.4 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RRPl_C4 PF17026.5 EGG42809.1 - 0.063 13.4 0.9 0.1 12.7 0.9 1.4 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Lar_restr_allev PF14354.6 EGG42809.1 - 0.077 13.4 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF1297 PF06973.12 EGG42811.1 - 6.3e-75 250.8 0.1 1.2e-74 250.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1297) DUF1246 PF06849.12 EGG42811.1 - 3.5e-47 159.4 0.0 6.4e-47 158.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) Flavoprotein PF02441.19 EGG42812.1 - 9.9e-30 103.4 0.5 1.2e-29 103.1 0.5 1.0 1 0 0 1 1 1 1 Flavoprotein MttA_Hcf106 PF02416.16 EGG42814.1 - 2.6e-11 42.7 1.5 3.3e-11 42.3 1.5 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family TatC PF00902.18 EGG42815.1 - 1.2e-50 172.2 16.3 1.4e-50 172.0 16.3 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Pox_P4B PF03292.14 EGG42818.1 - 0.039 12.2 0.4 0.042 12.1 0.4 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein YrhK PF14145.6 EGG42820.1 - 0.11 12.4 1.6 0.18 11.7 0.4 1.9 2 0 0 2 2 2 0 YrhK-like protein LPAM_1 PF08139.12 EGG42820.1 - 1.2 9.8 3.4 2 9.0 3.4 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Ferritin PF00210.24 EGG42822.1 - 4e-26 91.6 0.4 5.1e-26 91.3 0.4 1.1 1 0 0 1 1 1 1 Ferritin-like domain DALR_1 PF05746.15 EGG42823.1 - 2e-28 98.9 0.0 1.5e-27 96.1 0.0 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 EGG42823.1 - 1.4e-24 86.8 6.5 2.4e-20 72.8 0.5 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 EGG42823.1 - 0.00047 19.6 0.2 0.0014 18.0 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGG42823.1 - 0.0054 15.5 0.8 0.0092 14.8 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 EGG42823.1 - 0.041 12.8 0.4 0.13 11.2 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) PNPase PF03726.14 EGG42823.1 - 0.45 11.0 5.0 12 6.5 0.4 3.2 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain GCD14 PF08704.10 EGG42824.1 - 1.6e-35 122.9 0.1 5.8e-35 121.2 0.0 1.6 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGG42824.1 - 1.7e-09 37.7 0.1 2.4e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGG42824.1 - 1e-08 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG42824.1 - 9.3e-07 28.4 0.1 1.5e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGG42824.1 - 3.1e-06 27.8 0.0 5.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGG42824.1 - 0.00012 23.0 0.0 0.00028 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGG42824.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EGG42824.1 - 0.00031 21.4 0.0 0.00099 19.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGG42824.1 - 0.00033 20.4 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 EGG42824.1 - 0.00036 21.1 0.0 0.00073 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 EGG42824.1 - 0.00038 19.6 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin RrnaAD PF00398.20 EGG42824.1 - 0.00039 19.6 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 EGG42824.1 - 0.00081 19.1 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 EGG42824.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 EGG42824.1 - 0.0022 17.2 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase GCD14_N PF14801.6 EGG42824.1 - 0.0074 16.1 0.7 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_18 PF12847.7 EGG42824.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGG42824.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 EGG42824.1 - 0.035 13.9 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 EGG42824.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Carb_kinase PF01256.17 EGG42825.1 - 4.3e-47 160.7 0.7 5e-47 160.4 0.7 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EGG42825.1 - 7.9e-10 38.5 0.1 1.4e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EGG42825.1 - 3.1e-06 26.8 0.1 4.4e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Cation_ATPase PF13246.6 EGG42825.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Peptidase_M20 PF01546.28 EGG42826.1 - 2.3e-32 112.4 0.0 3.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG42826.1 - 2.5e-12 46.7 0.0 4.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DoxX PF07681.12 EGG42827.1 - 2.1e-14 53.9 5.6 2.1e-14 53.9 5.6 1.7 1 1 0 1 1 1 1 DoxX DoxD PF04173.13 EGG42827.1 - 1.1e-05 25.5 6.1 2.2e-05 24.4 5.8 1.6 1 1 1 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.6 EGG42827.1 - 1.1e-05 25.5 7.9 1.8e-05 24.7 7.8 1.5 1 1 0 1 1 1 1 DoxX-like family SURF4 PF02077.15 EGG42827.1 - 1.6 8.3 5.0 8.8 5.8 5.0 2.0 1 1 0 1 1 1 0 SURF4 family Proteasome PF00227.26 EGG42828.1 - 2.5e-46 157.6 0.0 3e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PUA PF01472.20 EGG42829.1 - 1e-16 60.7 0.7 1.4e-16 60.2 0.7 1.2 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EGG42829.1 - 0.014 15.6 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 UPF0113 PUA domain Homoserine_dh PF00742.19 EGG42830.1 - 1e-54 185.1 0.2 1.7e-54 184.4 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGG42830.1 - 1.1e-07 32.5 0.0 2.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EGG42830.1 - 1.6e-07 31.3 0.1 3.5e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SelR PF01641.18 EGG42831.1 - 1.3e-55 186.7 0.3 1.4e-55 186.5 0.3 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EGG42831.1 - 0.0062 16.7 2.6 0.018 15.3 1.9 1.9 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 EGG42831.1 - 0.0094 14.9 1.4 0.96 8.2 0.1 2.0 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding ADK_lid PF05191.14 EGG42831.1 - 0.082 12.9 5.2 0.33 11.0 1.2 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF983 PF06170.12 EGG42831.1 - 0.26 11.7 2.9 5.1 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Thy1 PF02511.15 EGG42832.1 - 6.1e-34 117.5 1.9 3.5e-18 66.1 2.3 2.3 2 0 0 2 2 2 2 Thymidylate synthase complementing protein TerC PF03741.16 EGG42834.1 - 1e-49 168.7 13.8 1e-49 168.7 13.8 2.1 3 0 0 3 3 3 1 Integral membrane protein TerC family YvbH_ext PF11724.8 EGG42836.1 - 0.028 14.7 0.2 0.069 13.5 0.2 1.7 1 0 0 1 1 1 0 YvbH-like oligomerisation region CdvA PF18822.1 EGG42837.1 - 8.7e-35 119.2 9.6 1.3e-34 118.7 9.6 1.2 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Fes1 PF08609.10 EGG42837.1 - 0.021 15.7 0.6 0.021 15.7 0.6 2.3 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 AAA_13 PF13166.6 EGG42837.1 - 0.025 13.3 10.5 0.031 12.9 10.5 1.0 1 0 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.23 EGG42837.1 - 0.059 13.7 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Baculo_PEP_C PF04513.12 EGG42837.1 - 0.073 13.1 0.7 0.16 12.0 0.7 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliT PF05400.13 EGG42837.1 - 0.36 11.7 10.2 3.8 8.4 0.0 2.9 2 1 1 3 3 3 0 Flagellar protein FliT MutS_III PF05192.18 EGG42837.1 - 1.1 9.5 4.6 1.7 8.8 4.6 1.3 1 0 0 1 1 1 0 MutS domain III DUF4407 PF14362.6 EGG42837.1 - 1.6 8.0 6.1 3.4 6.9 6.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MerR-DNA-bind PF09278.11 EGG42837.1 - 5.3 7.7 7.8 10 6.8 1.6 3.0 2 1 1 3 3 3 0 MerR, DNA binding TMPIT PF07851.13 EGG42837.1 - 9.4 5.4 10.2 12 5.0 0.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein AMP-binding PF00501.28 EGG42838.1 - 2.5e-93 313.0 0.0 3.1e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG42838.1 - 1.1e-24 87.1 0.4 3.5e-24 85.6 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGG42838.1 - 1.5e-15 56.8 4.5 3.8e-15 55.5 4.5 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PAS_9 PF13426.7 EGG42839.1 - 6.8e-10 39.1 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGG42839.1 - 6.4e-09 35.8 0.0 8.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGG42839.1 - 1.3e-05 25.4 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGG42839.1 - 0.0006 20.0 0.0 0.00074 19.7 0.0 1.1 1 0 0 1 1 1 1 PAS fold PheRS_DBD2 PF18554.1 EGG42839.1 - 0.64 10.0 4.4 0.19 11.8 0.9 2.0 2 0 0 2 2 2 0 PheRS DNA binding domain 2 HTH_20 PF12840.7 EGG42840.1 - 6.7e-07 29.3 0.2 2.8e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EGG42840.1 - 3.4e-06 26.8 0.0 0.00071 19.4 0.0 2.3 2 0 0 2 2 2 1 MarR family DUF4423 PF14394.6 EGG42840.1 - 5.7e-05 22.9 0.2 0.00019 21.2 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_Crp_2 PF13545.6 EGG42840.1 - 0.0025 17.7 0.1 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 EGG42840.1 - 0.0027 17.6 0.4 3.5 7.6 0.0 3.1 3 0 0 3 3 3 2 MarR family HTH_5 PF01022.20 EGG42840.1 - 0.0042 16.9 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF2250 PF10007.9 EGG42840.1 - 0.0055 16.8 0.3 0.37 10.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3449 PF11931.8 EGG42840.1 - 0.013 15.3 1.2 0.027 14.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF505 PF04458.12 EGG42840.1 - 0.016 13.6 0.0 0.019 13.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF505) HTH_45 PF14947.6 EGG42840.1 - 0.016 15.2 1.2 0.12 12.4 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DUF1724 PF08350.10 EGG42840.1 - 0.024 14.8 0.4 0.05 13.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) HTH_24 PF13412.6 EGG42840.1 - 0.029 13.9 0.2 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EGG42840.1 - 0.06 13.2 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DZR PF12773.7 EGG42841.1 - 0.041 13.9 9.0 0.097 12.7 9.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EGG42841.1 - 0.12 12.4 11.3 0.74 9.8 8.7 2.0 1 1 1 2 2 2 0 zinc-ribbons PolC_DP2 PF03833.13 EGG42841.1 - 0.58 7.9 8.4 0.63 7.8 8.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 EGG42841.1 - 1.4 9.3 13.2 1.2 9.5 9.7 2.1 1 1 1 2 2 2 0 C1 domain GBP PF02263.19 EGG42842.1 - 0.024 13.9 0.1 0.027 13.7 0.1 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain TauE PF01925.19 EGG42843.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE zinc_ribbon_15 PF17032.5 EGG42843.1 - 0.032 15.0 3.9 0.068 13.9 3.9 1.6 1 0 0 1 1 1 0 zinc-ribbon family XPG_I PF00867.18 EGG42844.1 - 6.4e-24 84.1 0.0 1.5e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGG42844.1 - 1.2e-21 77.0 0.1 8.4e-21 74.4 0.0 2.3 3 0 0 3 3 3 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EGG42844.1 - 0.00051 20.6 0.0 0.0013 19.2 0.0 1.9 1 1 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF4878 PF12870.7 EGG42844.1 - 0.31 11.3 2.4 0.27 11.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) DUF5368 PF17336.2 EGG42845.1 - 0.0049 17.0 0.8 0.0052 16.9 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5368) VIT1 PF01988.19 EGG42845.1 - 0.11 12.3 1.2 0.14 12.0 1.2 1.0 1 0 0 1 1 1 0 VIT family sCache_3_2 PF17203.4 EGG42845.1 - 0.13 12.4 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Single cache domain 3 Tetraspanin PF00335.20 EGG42845.1 - 0.19 11.4 3.9 0.23 11.2 3.9 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF3040 PF11239.8 EGG42845.1 - 9.3 6.6 6.1 4.8e+02 1.1 7.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) SAC3 PF12209.8 EGG42846.1 - 0.027 14.6 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain YodL PF14191.6 EGG42846.1 - 0.04 14.8 0.8 0.046 14.6 0.8 1.1 1 0 0 1 1 1 0 YodL-like CENP-B_N PF04218.13 EGG42846.1 - 0.12 12.0 0.6 3.3 7.4 0.0 2.7 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain HTH_45 PF14947.6 EGG42848.1 - 1.2e-06 28.4 0.2 1.3e-06 28.3 0.2 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 EGG42848.1 - 0.0098 15.7 0.0 0.011 15.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_5 PF01022.20 EGG42848.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 EGG42848.1 - 0.039 14.1 0.1 0.046 13.9 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF4393 PF14337.6 EGG42848.1 - 0.074 12.8 0.0 0.081 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) YfdX PF10938.8 EGG42851.1 - 0.14 12.1 2.3 12 5.8 0.0 3.7 4 2 0 4 4 4 0 YfdX protein DUF1771 PF08590.10 EGG42851.1 - 0.18 12.2 0.0 2.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) BLOC1_2 PF10046.9 EGG42851.1 - 0.63 10.4 5.0 0.3 11.4 0.3 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Guanylate_cyc PF00211.20 EGG42852.1 - 1.7e-16 60.4 0.1 2.4e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Sensor_TM1 PF13755.6 EGG42853.1 - 0.71 9.6 4.6 8.9 6.1 0.7 2.4 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Phage_holin_1 PF04531.13 EGG42853.1 - 1.1 9.8 7.9 0.19 12.3 1.0 2.5 1 1 2 3 3 3 0 Bacteriophage holin AHSA1 PF08327.11 EGG42854.1 - 2.4e-21 76.2 0.3 2.8e-21 76.1 0.3 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein S_locus_glycop PF00954.20 EGG42854.1 - 0.024 15.2 0.4 0.039 14.5 0.4 1.3 1 0 0 1 1 1 0 S-locus glycoprotein domain DUF960 PF06124.11 EGG42854.1 - 0.03 14.9 0.1 0.048 14.3 0.1 1.4 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) Polyketide_cyc2 PF10604.9 EGG42854.1 - 0.067 13.5 0.1 0.074 13.3 0.1 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ETRAMP PF09716.10 EGG42856.1 - 0.09 12.9 0.5 0.084 12.9 0.5 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Glyco_hydro_30C PF17189.4 EGG42857.1 - 0.12 12.6 0.8 20 5.5 0.7 2.8 2 1 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain MMR_HSR1_Xtn PF16897.5 EGG42859.1 - 4.8e-29 100.5 3.9 9.6e-29 99.5 3.9 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGG42859.1 - 1.9e-22 79.5 0.3 4.8e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EGG42859.1 - 4.5e-21 74.6 0.1 1.3e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 EGG42859.1 - 7e-15 54.9 2.0 9.9e-13 47.9 0.0 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG42859.1 - 5.4e-06 26.4 1.5 0.0076 16.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGG42859.1 - 0.00042 20.4 1.5 0.54 10.3 0.1 2.9 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 EGG42859.1 - 0.0013 18.2 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 EGG42859.1 - 0.0018 17.9 1.0 0.096 12.3 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 EGG42859.1 - 0.0031 17.0 1.7 0.037 13.5 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 EGG42859.1 - 0.0073 15.8 1.4 0.008 15.6 0.1 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGG42859.1 - 0.023 14.9 0.1 0.13 12.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGG42859.1 - 0.025 14.8 0.1 0.051 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG42859.1 - 0.025 15.0 0.4 0.17 12.3 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain MnmE_helical PF12631.7 EGG42859.1 - 0.055 13.6 0.1 0.076 13.2 0.1 1.2 1 0 0 1 1 1 0 MnmE helical domain Ras PF00071.22 EGG42859.1 - 0.067 12.8 1.2 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_33 PF13671.6 EGG42859.1 - 0.094 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain MJ1316 PF04457.12 EGG42860.1 - 0.0003 21.5 0.1 0.00039 21.1 0.1 1.1 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain HicB-like_2 PF15970.5 EGG42860.1 - 0.043 14.0 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system DUF3139 PF11337.8 EGG42862.1 - 0.016 15.9 5.5 0.074 13.7 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DUF2666 PF10869.8 EGG42862.1 - 0.021 15.0 0.8 0.028 14.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) DUF4817 PF16087.5 EGG42862.1 - 0.45 10.4 3.7 11 5.9 1.1 2.6 1 1 1 2 2 2 0 Helix-turn-helix domain (DUF4817) Band_7 PF01145.25 EGG42863.1 - 1.4e-23 83.9 6.5 2.2e-23 83.1 6.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family CdiA_C PF18451.1 EGG42863.1 - 0.081 13.2 0.5 0.17 12.1 0.5 1.5 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain Peptidase_S8 PF00082.22 EGG42864.1 - 2.6e-21 76.2 9.2 4.3e-14 52.5 0.6 2.9 2 1 0 2 2 2 2 Subtilase family FERM_F2 PF18377.1 EGG42864.1 - 0.0048 16.8 0.0 4.6 7.2 0.0 2.5 2 0 0 2 2 2 2 FERM F2 acyl-CoA binding protein-like domain DZR PF12773.7 EGG42866.1 - 0.015 15.3 0.9 0.019 15.0 0.9 1.1 1 0 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.13 EGG42866.1 - 0.016 13.1 0.0 0.016 13.1 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 HypA PF01155.19 EGG42866.1 - 0.036 14.1 0.1 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 EGG42866.1 - 0.041 13.7 1.1 0.053 13.4 1.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 EGG42866.1 - 0.44 10.1 6.7 2.9 7.5 0.4 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding MG2 PF01835.19 EGG42867.1 - 1.1e-27 96.3 0.4 5.8e-05 23.5 0.0 9.3 8 2 0 8 8 8 5 MG2 domain LTD PF00932.19 EGG42867.1 - 5.2e-17 62.2 2.5 4.9e-16 59.1 0.8 3.1 2 0 0 2 2 2 1 Lamin Tail Domain Arrestin_C PF02752.22 EGG42867.1 - 0.00026 21.4 4.9 3.3 8.2 0.0 6.6 7 1 0 7 7 7 1 Arrestin (or S-antigen), C-terminal domain Big_8 PF17961.1 EGG42867.1 - 0.082 13.1 1.5 1.9 8.7 0.1 3.2 2 0 0 2 2 2 0 Bacterial Ig domain Ribo_biogen_C PF04034.13 EGG42868.1 - 3.4e-38 130.2 0.0 4.7e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGG42868.1 - 8.5e-07 28.7 0.1 1.3e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SBP_bac_5 PF00496.22 EGG42869.1 - 1.3e-31 109.9 11.9 1.3e-25 90.2 0.0 3.5 3 1 0 3 3 3 3 Bacterial extracellular solute-binding proteins, family 5 Middle DUF4883 PF16224.5 EGG42870.1 - 0.027 14.7 3.2 0.03 14.5 3.2 1.0 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) Spectrin_like PF18373.1 EGG42870.1 - 0.058 13.5 0.1 0.072 13.2 0.1 1.1 1 0 0 1 1 1 0 Spectrin like domain DUF4355 PF14265.6 EGG42870.1 - 0.061 13.6 0.6 0.066 13.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Mrr_cat PF04471.12 EGG42871.1 - 0.0037 17.3 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease NERD PF08378.11 EGG42871.1 - 0.031 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Nuclease-related domain UPF0102 PF02021.17 EGG42871.1 - 0.086 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 DUF2070 PF09843.9 EGG42872.1 - 2.3e-119 399.3 1.9 2.8e-119 399.0 1.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) MapZ_C2 PF18708.1 EGG42872.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 IncD PF17628.2 EGG42872.1 - 3.4 7.4 4.6 9.3 6.0 2.1 2.4 1 1 1 2 2 2 0 Inclusion membrane protein D Sec61_beta PF03911.16 EGG42873.1 - 5.4e-13 48.7 0.4 6.4e-13 48.5 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family Auto_anti-p27 PF06677.12 EGG42874.1 - 1.3e-09 38.1 2.4 1.9e-09 37.5 2.4 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TIP120 PF08623.10 EGG42874.1 - 0.013 15.3 3.7 0.015 15.1 3.7 1.1 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF1178 PF06676.11 EGG42874.1 - 0.024 15.0 0.5 0.032 14.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF3422 PF11902.8 EGG42874.1 - 0.21 10.7 1.7 0.24 10.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) FUSC-like PF12805.7 EGG42874.1 - 0.23 10.5 1.5 0.27 10.3 1.5 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS TF_Zn_Ribbon PF08271.12 EGG42874.1 - 0.82 9.2 3.6 1.1 8.9 1.5 2.2 2 1 0 2 2 2 0 TFIIB zinc-binding Holin_BhlA PF10960.8 EGG42874.1 - 1.5 8.8 6.0 3 7.9 6.0 1.6 1 1 0 1 1 1 0 BhlA holin family SUI1 PF01253.22 EGG42875.1 - 2e-18 66.7 0.0 2.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DTW PF03942.15 EGG42875.1 - 0.015 15.0 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 DTW domain CPBP PF02517.16 EGG42876.1 - 4e-12 46.3 11.8 1.5e-11 44.5 11.8 2.1 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease CofC PF01983.16 EGG42877.1 - 2.8e-13 49.6 3.1 3.2e-13 49.4 3.1 1.0 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 EGG42877.1 - 5.5e-05 23.6 0.0 5.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 EGG42877.1 - 0.02 14.8 0.7 0.026 14.4 0.7 1.4 1 1 0 1 1 1 0 Cytidylyltransferase UPF0052 PF01933.18 EGG42878.1 - 2.7e-58 197.5 0.1 3.1e-58 197.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF1459 PF07312.11 EGG42879.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Methyltransf_11 PF08241.12 EGG42881.1 - 1.3e-18 67.4 0.0 2.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG42881.1 - 5.4e-18 65.4 0.0 6.8e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG42881.1 - 7.4e-16 58.6 0.0 1.7e-15 57.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG42881.1 - 9.8e-16 58.3 0.0 1.9e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG42881.1 - 3.6e-14 52.8 0.4 4.9e-14 52.4 0.4 1.3 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGG42881.1 - 7.3e-10 38.8 0.0 8.5e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 EGG42881.1 - 1.4e-09 37.3 0.1 3.7e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EGG42881.1 - 2e-08 33.9 0.6 2.9e-08 33.3 0.6 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGG42881.1 - 1.1e-07 31.5 0.1 4.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase MetW PF07021.12 EGG42881.1 - 1.5e-07 31.2 0.1 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 EGG42881.1 - 2.8e-05 23.7 0.1 0.00031 20.3 0.0 2.1 1 1 1 2 2 2 1 Histone methylation protein DOT1 AdoMet_MTase PF07757.13 EGG42881.1 - 0.00011 22.4 0.9 0.00023 21.5 0.0 1.9 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 EGG42881.1 - 0.00013 21.4 0.5 0.00016 21.1 0.5 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 EGG42881.1 - 0.0015 18.0 0.1 0.0021 17.5 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EGG42881.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EGG42881.1 - 0.0019 17.5 0.2 0.019 14.3 0.0 2.1 1 1 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 EGG42881.1 - 0.0024 17.9 0.1 0.0051 16.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 EGG42881.1 - 0.0032 16.6 0.1 0.0043 16.2 0.1 1.3 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 EGG42881.1 - 0.0069 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EGG42881.1 - 0.032 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3905 PF13045.6 EGG42881.1 - 0.041 13.9 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) Methyltransf_2 PF00891.18 EGG42881.1 - 0.059 12.7 0.0 0.2 10.9 0.0 1.9 1 1 1 2 2 2 0 O-methyltransferase domain MetOD2 PF18548.1 EGG42882.1 - 0.032 14.3 0.5 0.17 12.0 0.5 2.3 1 1 0 1 1 1 0 Metanogen output domain 2 FlgD_ig PF13860.6 EGG42882.1 - 0.13 12.2 0.0 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 FlgD Ig-like domain DUF4363 PF14276.6 EGG42882.1 - 0.14 12.3 0.0 0.14 12.3 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4363) MRP-L28 PF09812.9 EGG42882.1 - 0.26 11.4 1.3 1 9.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Gp_dh_C PF02800.20 EGG42882.1 - 0.34 10.5 1.8 0.46 10.1 0.1 2.1 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Cytochrom_B562 PF07361.11 EGG42882.1 - 0.87 10.3 3.1 13 6.5 0.0 3.9 4 0 0 4 4 4 0 Cytochrome b562 DAO PF01266.24 EGG42883.1 - 1.2e-16 61.3 0.5 1e-07 31.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGG42883.1 - 1.9e-15 56.9 0.0 3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGG42883.1 - 1e-13 51.5 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGG42883.1 - 1e-11 44.4 0.2 1.6e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 EGG42883.1 - 1.7e-11 43.9 0.5 4.4e-07 29.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGG42883.1 - 7.8e-10 38.5 2.4 9.8e-07 28.3 0.3 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG42883.1 - 3.7e-08 32.5 0.4 3.6e-06 26.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 EGG42883.1 - 9.8e-08 31.4 0.1 1.4e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGG42883.1 - 2.5e-06 27.6 0.1 6.4e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGG42883.1 - 3.7e-06 26.3 0.8 1e-05 24.8 0.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EGG42883.1 - 5.6e-06 25.8 1.1 5.5e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EGG42883.1 - 3.2e-05 23.3 1.3 0.0001 21.7 1.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG42883.1 - 8.8e-05 23.0 1.5 0.058 14.0 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGG42883.1 - 0.025 14.5 0.1 0.061 13.2 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 EGG42883.1 - 0.09 12.1 0.3 0.73 9.1 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase TrkA_N PF02254.18 EGG42883.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF3797 PF12677.7 EGG42884.1 - 0.055 13.4 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zinc-ribbon_6 PF10005.9 EGG42884.1 - 0.099 13.3 0.1 0.15 12.8 0.1 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf_UBZ PF18439.1 EGG42884.1 - 0.17 11.5 0.4 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF99 PF01949.16 EGG42885.1 - 4.7e-54 182.6 0.0 5.3e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 adh_short_C2 PF13561.6 EGG42886.1 - 3.3e-67 226.5 0.2 3.7e-67 226.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG42886.1 - 6.1e-60 202.0 1.0 7.2e-60 201.8 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG42886.1 - 1.3e-08 35.0 0.3 1.8e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG42886.1 - 1.3e-05 24.8 0.9 3.3e-05 23.5 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EGG42886.1 - 0.00027 21.5 1.2 0.00047 20.7 0.5 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EGG42886.1 - 0.0031 17.4 0.3 0.0052 16.7 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EGG42886.1 - 0.0052 16.2 1.4 0.021 14.3 1.4 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG42886.1 - 0.006 15.8 2.4 0.0081 15.3 2.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.15 EGG42886.1 - 0.009 15.9 0.2 0.017 15.0 0.2 1.4 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein 5_nucleotid_C PF02872.18 EGG42886.1 - 0.024 14.8 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF1776 PF08643.10 EGG42886.1 - 0.062 12.7 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2660 PF10859.8 EGG42886.1 - 0.12 12.9 0.0 0.46 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) NAD_binding_11 PF14833.6 EGG42887.1 - 1.7e-10 41.2 0.0 1.9e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EGG42888.1 - 8.9e-37 126.7 0.4 1.2e-36 126.3 0.4 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG42888.1 - 9.7e-09 35.7 1.0 3.1e-08 34.1 0.5 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGG42888.1 - 1.6e-06 28.2 0.2 2.6e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGG42888.1 - 7e-06 25.5 0.1 1.2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGG42888.1 - 2.7e-05 23.8 0.1 4.4e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 EGG42888.1 - 8.7e-05 22.2 0.2 0.00016 21.3 0.1 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 EGG42888.1 - 0.0001 22.0 1.8 0.016 14.8 0.1 2.1 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGG42888.1 - 0.00016 21.6 0.2 0.0029 17.5 0.3 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EGG42888.1 - 0.0012 18.7 0.0 0.069 13.0 0.0 2.2 1 1 1 2 2 2 1 Rossmann-like domain NAD_binding_11 PF14833.6 EGG42888.1 - 0.0012 19.0 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EGG42888.1 - 0.0014 18.6 0.3 0.0076 16.2 0.1 2.1 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EGG42888.1 - 0.1 12.9 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-H2C2_5 PF13909.6 EGG42890.1 - 3e-05 23.7 0.7 4.4e-05 23.1 0.7 1.2 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EGG42890.1 - 0.00049 20.4 1.3 0.00078 19.8 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG42890.1 - 0.0016 19.1 1.4 0.0029 18.3 1.4 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger OrsD PF12013.8 EGG42890.1 - 0.071 13.6 0.0 0.082 13.4 0.0 1.2 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Peripla_BP_2 PF01497.18 EGG42892.1 - 1.3e-22 80.5 0.0 1.9e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Nre_N PF04894.12 EGG42893.1 - 1.8e-74 251.0 0.0 2.5e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 EGG42893.1 - 4.9e-32 110.1 0.0 7.7e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal Nre, C-terminal SRTM1 PF15872.5 EGG42894.1 - 0.29 11.3 0.0 0.29 11.3 0.0 2.5 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 DUF998 PF06197.13 EGG42894.1 - 5.8 6.5 18.9 0.042 13.4 7.7 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF998) IMS PF00817.20 EGG42895.1 - 3.3e-41 140.7 0.2 3.5e-40 137.4 0.1 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EGG42895.1 - 1.8e-10 41.5 0.2 4.1e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGG42895.1 - 6.8e-07 29.3 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif UPF0242 PF06785.11 EGG42895.1 - 0.0046 17.1 3.3 0.0073 16.4 3.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Pneumo_ncap PF03246.13 EGG42895.1 - 0.0061 15.4 0.1 0.0091 14.8 0.1 1.2 1 0 0 1 1 1 1 Pneumovirus nucleocapsid protein Cdd1 PF11731.8 EGG42895.1 - 0.0081 16.4 0.2 0.049 13.9 0.0 2.4 3 1 1 4 4 4 1 Pathogenicity locus DUF2524 PF10732.9 EGG42895.1 - 0.022 15.1 2.7 0.027 14.8 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) 7TMR-HDED PF07697.11 EGG42895.1 - 0.048 13.8 1.7 0.19 11.8 1.7 2.0 1 1 0 1 1 1 0 7TM-HD extracellular DUF5071 PF16804.5 EGG42895.1 - 0.11 12.8 0.5 0.24 11.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) NPV_P10 PF05531.12 EGG42895.1 - 0.91 10.0 5.7 6.9 7.2 1.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Alba PF01918.21 EGG42897.1 - 1.7e-12 47.0 1.0 2.3e-12 46.5 1.0 1.2 1 0 0 1 1 1 1 Alba Methyltrn_RNA_3 PF02598.17 EGG42897.1 - 0.027 14.0 0.3 0.034 13.7 0.3 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase PRCC PF10253.9 EGG42897.1 - 0.25 12.1 3.6 0.27 12.0 3.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SPATA3 PF15662.5 EGG42897.1 - 0.32 11.6 15.4 0.43 11.2 14.7 1.6 1 1 1 2 2 2 0 Spermatogenesis-associated protein 3 family LysE PF01810.18 EGG42899.1 - 1.5e-29 102.8 15.1 2e-29 102.4 15.1 1.1 1 0 0 1 1 1 1 LysE type translocator CRPA PF05745.11 EGG42899.1 - 0.051 13.6 1.3 0.081 12.9 0.2 1.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) GWT1 PF06423.12 EGG42899.1 - 0.8 9.8 7.9 3.3 7.8 7.9 1.9 1 1 0 1 1 1 0 GWT1 PAC2 PF09754.9 EGG42900.1 - 2.2e-18 67.0 0.0 2.7e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DS PF01916.17 EGG42901.1 - 1.7e-90 303.2 0.1 2e-90 303.0 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Inos-1-P_synth PF01658.17 EGG42902.1 - 1.2e-29 102.8 0.4 3.2e-28 98.2 0.0 2.2 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase RuvX PF03652.15 EGG42902.1 - 0.026 14.9 0.0 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Holliday junction resolvase MS_channel PF00924.18 EGG42902.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel RexA PF15969.5 EGG42902.1 - 0.068 12.7 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Intracellular sensor of Lambda phage, Abi component CobU PF02283.16 EGG42902.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SMC_N PF02463.19 EGG42903.1 - 4e-48 163.8 35.2 2e-26 92.8 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGG42903.1 - 1.7e-18 67.0 0.0 8.3e-18 64.8 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGG42903.1 - 3.3e-09 37.0 29.2 1.5e-05 24.9 5.1 5.0 2 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG42903.1 - 8.2e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tubulin_3 PF14881.6 EGG42903.1 - 0.0014 18.3 0.1 0.0082 15.8 0.1 2.4 1 0 0 1 1 1 1 Tubulin domain ATG16 PF08614.11 EGG42903.1 - 0.0092 16.2 8.2 0.0092 16.2 8.2 6.7 2 2 4 6 6 6 2 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 EGG42903.1 - 0.067 13.4 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EGG42903.1 - 0.33 11.4 122.2 9.2 6.7 63.5 7.5 2 2 1 3 3 3 0 AAA domain APG6_N PF17675.1 EGG42903.1 - 0.64 10.5 112.7 0.061 13.9 11.2 8.8 3 2 6 9 9 9 0 Apg6 coiled-coil region AAA_15 PF13175.6 EGG42903.1 - 1.5 8.4 94.1 1.5e+02 1.9 46.6 4.5 2 2 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EGG42904.1 - 8.6e-34 117.0 0.1 1.2e-33 116.5 0.1 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EGG42904.1 - 2.3e-17 63.2 0.3 5.1e-17 62.2 0.1 1.7 2 0 0 2 2 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EGG42904.1 - 1.8e-05 24.3 0.4 3e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG42904.1 - 0.00014 22.3 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG42904.1 - 0.00015 22.0 0.9 0.0024 18.1 0.9 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGG42904.1 - 0.00055 19.9 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGG42904.1 - 0.0011 18.6 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EGG42904.1 - 0.0012 19.3 0.5 0.02 15.3 0.5 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EGG42904.1 - 0.0013 18.7 0.4 1.1 9.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EGG42904.1 - 0.0016 17.7 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_15 PF13175.6 EGG42904.1 - 0.0024 17.6 0.2 0.0035 17.1 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EGG42904.1 - 0.0033 16.5 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein G-alpha PF00503.20 EGG42904.1 - 0.0086 15.3 0.2 0.011 14.9 0.2 1.2 1 0 0 1 1 1 1 G-protein alpha subunit RNA_helicase PF00910.22 EGG42904.1 - 0.0098 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EGG42904.1 - 0.013 15.0 0.1 0.036 13.6 0.1 1.7 1 1 1 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGG42904.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 EGG42904.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG42904.1 - 0.026 14.4 0.1 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 NTPase DnaB_C PF03796.15 EGG42904.1 - 0.028 13.8 0.1 0.061 12.7 0.1 1.5 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 EGG42904.1 - 0.034 13.5 0.4 0.24 10.7 0.1 2.1 2 0 0 2 2 2 0 KaiC DUF87 PF01935.17 EGG42904.1 - 0.037 14.1 1.6 0.061 13.4 0.3 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 EGG42904.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Phage_TAC_13 PF16459.5 EGG42904.1 - 0.053 14.0 0.2 0.17 12.4 0.2 1.8 1 1 0 1 1 1 0 Phage tail assembly chaperone, TAC AAA_5 PF07728.14 EGG42904.1 - 0.073 13.1 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 EGG42904.1 - 0.088 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 EGG42904.1 - 0.1 12.3 0.1 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 EGG42904.1 - 0.1 13.1 0.1 0.1 13.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain Membralin PF09746.9 EGG42904.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein AAA_30 PF13604.6 EGG42904.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGG42904.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGG42904.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Methyltransf_33 PF10017.9 EGG42905.1 - 1.2e-100 336.7 0.8 1.3e-100 336.6 0.8 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_23 PF13489.6 EGG42905.1 - 0.02 14.8 0.0 0.25 11.1 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain FGE-sulfatase PF03781.16 EGG42906.1 - 1.8e-48 165.4 2.7 3.4e-48 164.5 2.7 1.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EGG42906.1 - 3.4e-08 34.1 0.0 1.3e-07 32.1 0.0 2.0 2 1 0 2 2 2 1 DinB superfamily DinB PF05163.12 EGG42906.1 - 0.13 12.2 0.1 0.38 10.6 0.1 1.9 1 1 0 1 1 1 0 DinB family E3_UbLigase_R4 PF13764.6 EGG42906.1 - 0.17 10.0 1.0 0.27 9.3 1.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 ProRS-C_1 PF09180.11 EGG42907.1 - 4e-20 71.8 1.5 4e-20 71.8 1.5 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EGG42907.1 - 3.8e-18 66.1 0.0 5.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG42907.1 - 2.3e-17 62.9 0.2 6.1e-17 61.6 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain HAD PF12710.7 EGG42910.1 - 5.1e-10 40.0 0.0 6.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG42910.1 - 7.5e-10 39.4 0.0 2.4e-08 34.5 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG42910.1 - 8.5e-05 22.4 0.7 0.00077 19.3 0.5 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase F420_ligase PF01996.16 EGG42911.1 - 1.1e-56 192.0 1.2 1.3e-56 191.7 1.2 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase PHP_C PF13263.6 EGG42912.1 - 5e-10 39.0 0.0 1.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 PHP-associated EF-hand_2 PF09068.11 EGG42912.1 - 0.2 11.8 2.2 0.74 10.0 2.2 2.1 1 1 0 1 1 1 0 EF hand Trypsin_2 PF13365.6 EGG42913.1 - 7.1e-33 114.6 0.3 1.4e-32 113.7 0.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EGG42913.1 - 7.1e-15 55.1 1.1 1.5e-14 54.0 0.3 2.1 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 EGG42913.1 - 2.2e-14 53.8 4.5 2.5e-14 53.6 0.3 2.3 1 1 0 2 2 2 1 Trypsin PDZ_6 PF17820.1 EGG42913.1 - 6.9e-05 22.6 1.6 0.038 13.8 0.1 3.3 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 EGG42913.1 - 0.018 15.4 4.7 5.8 7.4 1.5 3.9 3 1 0 3 3 3 0 PDZ domain Peptidase_S29 PF02907.15 EGG42913.1 - 0.018 14.8 0.6 0.048 13.4 0.0 2.1 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 EGG42913.1 - 0.61 8.7 3.4 0.21 10.2 0.7 1.6 2 0 0 2 2 2 0 Peptidase S46 TusA PF01206.17 EGG42914.1 - 4.7e-22 77.6 0.0 5.2e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA PALP PF00291.25 EGG42915.1 - 6.6e-64 216.1 0.0 9.8e-64 215.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KASH_CCD PF14662.6 EGG42916.1 - 0.0012 18.7 9.2 0.0016 18.3 9.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-C2HC_2 PF13913.6 EGG42917.1 - 0.0095 15.8 0.2 0.0095 15.8 0.2 2.1 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C3HC4 PF00097.25 EGG42917.1 - 0.024 14.5 2.2 2.2 8.2 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG42917.1 - 0.063 13.3 2.7 2.2 8.3 0.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG42917.1 - 0.067 13.2 1.4 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger ECM11 PF15463.6 EGG42917.1 - 0.08 13.5 0.1 0.082 13.5 0.1 1.1 1 0 0 1 1 1 0 Extracellular mutant protein 11 Response_reg PF00072.24 EGG42918.1 - 4.7e-16 58.9 0.5 5.3e-16 58.8 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF2584 PF10763.9 EGG42918.1 - 0.025 14.7 0.1 0.047 13.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2584) CNDH2_M PF16869.5 EGG42918.1 - 0.12 13.0 0.0 0.16 12.7 0.0 1.2 1 0 0 1 1 1 0 PF16858 DUF1059 PF06348.11 EGG42919.1 - 9.4e-14 51.4 0.2 1.1e-13 51.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) DUF2653 PF10850.8 EGG42919.1 - 0.096 12.9 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) Pyr_redox_2 PF07992.14 EGG42920.1 - 1.9e-52 178.4 0.8 2.2e-52 178.2 0.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG42920.1 - 8.9e-26 90.8 3.5 1.2e-22 80.6 0.4 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG42920.1 - 1.9e-18 66.8 3.4 3.1e-17 62.9 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGG42920.1 - 7.7e-07 28.5 2.1 0.0095 15.1 0.1 3.4 3 1 0 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.6 EGG42920.1 - 3e-05 23.3 0.1 0.16 11.1 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGG42920.1 - 9.5e-05 22.1 2.3 0.033 13.8 0.0 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGG42920.1 - 0.00015 21.2 1.0 0.12 11.6 0.1 2.7 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EGG42920.1 - 0.00046 19.7 0.1 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGG42920.1 - 0.00051 19.4 0.0 0.0058 15.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EGG42920.1 - 0.0006 19.0 3.8 0.0096 15.0 0.1 3.4 2 1 2 4 4 4 1 FAD binding domain NAD_binding_9 PF13454.6 EGG42920.1 - 0.0053 16.8 4.2 1.2 9.1 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGG42920.1 - 0.0082 14.9 2.7 0.17 10.6 0.1 3.0 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.6 EGG42920.1 - 0.012 16.1 0.3 0.049 14.1 0.1 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EGG42920.1 - 0.012 15.9 0.4 0.044 14.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MAF_flag10 PF01973.18 EGG42920.1 - 0.027 14.2 0.0 6.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF115 ATP-cone PF03477.16 EGG42922.1 - 4.2e-07 30.5 0.1 1.1e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 ATP cone domain NERD PF08378.11 EGG42922.1 - 0.13 12.7 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Nuclease-related domain DUF1910 PF08928.10 EGG42923.1 - 0.19 11.7 3.5 0.18 11.8 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) Thi4 PF01946.17 EGG42924.1 - 9.5e-65 218.1 0.1 1.2e-64 217.8 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGG42924.1 - 1.3e-13 50.9 0.2 9.4e-07 28.2 0.0 3.0 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EGG42924.1 - 1.2e-09 38.1 0.0 2.5e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG42924.1 - 3.7e-08 33.0 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG42924.1 - 1.9e-07 31.2 0.0 4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGG42924.1 - 2e-06 27.3 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGG42924.1 - 2e-06 27.6 0.2 0.00028 20.6 0.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG42924.1 - 2.8e-06 26.3 0.0 4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGG42924.1 - 9.7e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG42924.1 - 0.00014 21.0 0.5 0.0018 17.4 0.0 2.3 2 1 1 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 EGG42924.1 - 0.00029 20.0 0.1 0.00048 19.3 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGG42924.1 - 0.0058 15.5 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 EGG42924.1 - 0.0095 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EGG42924.1 - 0.0099 15.2 0.0 0.024 14.0 0.1 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EGG42924.1 - 0.018 15.6 0.1 0.062 13.9 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EGG42924.1 - 0.052 12.1 0.0 0.098 11.2 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_9 PF13454.6 EGG42924.1 - 0.067 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EGG42924.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain SpoIIM PF01944.17 EGG42925.1 - 1.2e-05 25.4 14.0 1.4e-05 25.1 14.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein M NIR_SIR PF01077.22 EGG42926.1 - 7.5e-42 142.5 0.0 3.7e-32 111.0 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EGG42926.1 - 4.9e-30 103.2 0.0 2.2e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Rhodanese PF00581.20 EGG42927.1 - 3.2e-36 124.1 0.0 5.1e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain TPR_2 PF07719.17 EGG42928.1 - 1.3e-19 68.6 6.8 1e-06 28.4 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG42928.1 - 1.3e-18 66.0 8.2 9.5e-07 28.4 0.1 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGG42928.1 - 3.9e-13 49.7 3.7 2.2e-08 34.5 0.1 3.0 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG42928.1 - 5.7e-13 48.3 0.2 0.0022 18.2 0.0 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG42928.1 - 1.2e-12 47.3 3.5 0.00053 19.6 0.2 4.5 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 EGG42928.1 - 3.6e-11 42.4 9.9 0.0011 19.0 0.1 6.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG42928.1 - 3.9e-11 43.4 0.1 0.00078 20.0 0.0 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG42928.1 - 1.3e-10 41.2 2.1 0.005 17.6 0.0 5.3 4 1 2 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG42928.1 - 9.1e-09 35.4 0.2 2.5e-08 34.0 0.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGG42928.1 - 3.5e-08 33.6 3.6 6.3e-06 26.4 0.2 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG42928.1 - 2.7e-06 27.4 0.0 0.0008 19.5 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG42928.1 - 2.9e-06 27.2 0.2 0.11 12.6 0.0 3.8 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EGG42928.1 - 5.9e-06 26.6 3.8 7.8 7.4 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG42928.1 - 0.0001 22.1 0.4 8.5 6.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGG42928.1 - 0.0005 20.1 0.4 0.0013 18.7 0.4 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat HTH_27 PF13463.6 EGG42928.1 - 0.00052 20.4 0.2 0.0024 18.3 0.2 2.2 2 0 0 2 2 1 1 Winged helix DNA-binding domain TPR_7 PF13176.6 EGG42928.1 - 0.0032 17.4 0.2 32 4.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGG42928.1 - 0.013 14.9 2.7 0.076 12.4 0.1 2.9 2 1 3 5 5 5 0 Coatomer epsilon subunit NARP1 PF12569.8 EGG42928.1 - 0.014 14.4 2.8 0.21 10.4 0.0 2.6 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 Ferritin PF00210.24 EGG42928.1 - 0.016 15.1 2.6 0.98 9.3 0.2 2.9 3 0 0 3 3 3 0 Ferritin-like domain TPR_20 PF14561.6 EGG42928.1 - 0.028 14.8 0.9 2.5 8.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps4_C PF09336.10 EGG42928.1 - 0.047 13.7 0.9 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF1840 PF08895.11 EGG42928.1 - 0.07 13.5 1.1 1.7 9.0 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF1840) Flagellin_C PF00700.21 EGG42928.1 - 0.074 13.4 0.3 0.9 9.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region TrmB PF01978.19 EGG42928.1 - 0.077 12.9 0.0 7.2 6.6 0.0 2.9 3 0 0 3 3 2 0 Sugar-specific transcriptional regulator TrmB TPR_3 PF07720.12 EGG42928.1 - 0.17 11.9 4.9 11 6.2 0.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Radical_SAM PF04055.21 EGG42929.1 - 6.9e-09 36.3 0.1 1.1e-08 35.6 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily AP_endonuc_2 PF01261.24 EGG42929.1 - 0.056 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PEP_hydrolase PF09370.10 EGG42929.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DUF4364 PF14277.6 EGG42930.1 - 0.0041 16.9 0.1 0.0086 15.8 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_45 PF14947.6 EGG42930.1 - 0.033 14.2 0.2 0.075 13.0 0.1 1.7 1 1 1 2 2 2 0 Winged helix-turn-helix Radical_SAM PF04055.21 EGG42931.1 - 7.1e-12 46.0 0.0 2e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily BATS PF06968.13 EGG42931.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain CdvA PF18822.1 EGG42931.1 - 0.45 10.4 0.1 0.45 10.4 0.1 3.3 5 0 0 5 5 5 0 CdvA-like coiled-coil domain Trypsin_2 PF13365.6 EGG42932.1 - 2.4e-33 116.2 0.3 4.1e-33 115.4 0.3 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGG42932.1 - 1.3e-14 54.6 0.6 7.1e-14 52.1 0.2 2.3 2 1 0 2 2 2 1 Trypsin PDZ_2 PF13180.6 EGG42932.1 - 2.2e-13 50.3 3.8 4.5e-13 49.3 0.5 2.7 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGG42932.1 - 2.7e-06 27.1 2.0 0.015 15.1 0.3 3.3 3 0 0 3 3 3 2 PDZ domain Peptidase_S29 PF02907.15 EGG42932.1 - 0.0044 16.8 0.1 0.0086 15.8 0.1 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.21 EGG42932.1 - 0.011 15.5 2.9 0.029 14.2 0.5 2.4 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 EGG42932.1 - 0.014 14.0 1.1 0.02 13.5 0.3 1.5 2 0 0 2 2 2 0 Peptidase S46 PDZ PF00595.24 EGG42932.1 - 0.015 15.6 2.5 2.7 8.4 0.5 3.2 3 0 0 3 3 3 0 PDZ domain Peptidase_S32 PF05579.13 EGG42932.1 - 0.039 13.1 2.7 7.6 5.6 2.7 2.3 1 1 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Glycos_transf_2 PF00535.26 EGG42933.1 - 1.8e-27 96.2 0.0 2.5e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGG42933.1 - 3.8e-20 72.8 0.0 5.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGG42933.1 - 2.8e-09 36.7 0.0 5.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGG42933.1 - 6.3e-07 29.1 0.1 9.8e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGG42933.1 - 0.00023 21.6 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 EGG42933.1 - 0.091 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Anp1 Polyketide_cyc2 PF10604.9 EGG42934.1 - 5.6e-10 39.6 0.0 6e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EGG42934.1 - 2.4e-05 24.6 0.0 3e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EGG42934.1 - 0.066 13.5 0.1 0.077 13.2 0.1 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein tRNA_bind PF01588.20 EGG42936.1 - 3.6e-22 78.3 0.0 4e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain TBP PF00352.21 EGG42937.1 - 5.9e-55 183.2 0.0 2.2e-27 94.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGG42937.1 - 6.3e-08 32.6 0.0 0.00046 20.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) RTT107_BRCT_5 PF16770.5 EGG42937.1 - 0.098 12.5 0.2 0.33 10.8 0.1 1.8 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF1512 PF07431.12 EGG42938.1 - 3.2e-131 437.6 6.7 3.6e-131 437.4 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) Linker_histone PF00538.19 EGG42938.1 - 0.29 11.5 3.7 1.4 9.3 0.1 2.8 3 0 0 3 3 3 0 linker histone H1 and H5 family Peptidase_M24 PF00557.24 EGG42939.1 - 2.6e-34 118.8 1.1 4.4e-34 118.0 1.1 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 HSR PF03172.13 EGG42939.1 - 0.0083 16.3 0.2 1.2 9.4 0.1 2.4 2 0 0 2 2 2 2 HSR domain ApbE PF02424.15 EGG42939.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 ApbE family ATP-cone PF03477.16 EGG42939.1 - 0.28 11.8 4.5 5.4 7.7 0.2 3.1 3 1 0 3 3 3 0 ATP cone domain Peptidase_M78 PF06114.13 EGG42940.1 - 0.12 12.3 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain Response_reg PF00072.24 EGG42941.1 - 5.1e-24 84.6 1.0 1.3e-23 83.3 1.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain TrmB PF01978.19 EGG42941.1 - 5.7e-14 51.8 0.0 1.6e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 EGG42941.1 - 2.1e-05 23.9 1.2 2.9e-05 23.4 0.6 1.5 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB Adenine_glyco PF03352.13 EGG42941.1 - 0.18 11.6 1.4 9.9 5.9 0.1 2.5 2 0 0 2 2 2 0 Methyladenine glycosylase DisA-linker PF10635.9 EGG42941.1 - 0.58 9.9 5.4 5 6.9 0.8 2.9 3 0 0 3 3 3 0 DisA bacterial checkpoint controller linker region HATPase_c PF02518.26 EGG42942.1 - 1.2e-21 77.3 0.1 2.6e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG42942.1 - 6e-10 39.0 0.1 2.5e-09 37.1 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EGG42942.1 - 4.8e-09 36.5 0.0 1.9e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 HAMP domain 4HB_MCP_1 PF12729.7 EGG42942.1 - 6.4e-09 35.6 12.0 6.4e-09 35.6 12.0 3.0 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction HATPase_c_5 PF14501.6 EGG42942.1 - 8e-09 35.3 0.7 5.7e-08 32.6 0.1 2.6 2 1 1 3 3 3 1 GHKL domain HATPase_c_3 PF13589.6 EGG42942.1 - 0.014 15.3 0.2 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma_reg_N PF13800.6 EGG42942.1 - 0.42 10.9 8.6 0.36 11.2 1.0 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2884 PF11101.8 EGG42942.1 - 1 8.8 5.1 0.52 9.8 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Syntaxin-6_N PF09177.11 EGG42942.1 - 2.5 8.7 6.3 2.3 8.8 0.2 3.4 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Chorismate_synt PF01264.21 EGG42943.1 - 8.8e-135 448.6 0.2 1e-134 448.4 0.2 1.0 1 0 0 1 1 1 1 Chorismate synthase BCIP PF13862.6 EGG42943.1 - 0.056 13.2 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 p21-C-terminal region-binding protein HATPase_c PF02518.26 EGG42944.1 - 1e-15 58.2 0.4 2.2e-15 57.1 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EGG42944.1 - 7.2e-10 39.1 0.0 2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 EGG42944.1 - 1.4e-08 34.6 0.3 3.8e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EGG42944.1 - 3e-07 30.6 0.0 6.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 EGG42944.1 - 7.7e-07 29.0 0.6 2e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 GHKL domain PAS PF00989.25 EGG42944.1 - 0.00025 21.0 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGG42944.1 - 0.002 18.4 0.0 0.0041 17.4 0.0 1.6 2 0 0 2 2 2 1 PAS fold EPSP_synthase PF00275.20 EGG42945.1 - 1.1e-103 347.2 0.0 1.3e-103 346.9 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GHMP_kinases_N PF00288.26 EGG42946.1 - 1.6e-09 37.8 0.2 3.3e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG42946.1 - 4.7e-06 26.9 0.1 0.00011 22.5 0.1 2.5 1 1 0 1 1 1 1 GHMP kinases C terminal RNase_PH PF01138.21 EGG42946.1 - 0.063 13.8 1.3 0.12 12.8 1.3 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Shikimate_dh_N PF08501.11 EGG42947.1 - 9.5e-28 96.3 0.0 2.5e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EGG42947.1 - 1.4e-12 47.1 0.1 2.2e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EGG42947.1 - 6.9e-12 45.6 0.3 1.2e-11 44.9 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGG42947.1 - 3.4e-06 27.3 1.8 5.6e-06 26.6 1.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGG42947.1 - 0.004 17.7 0.4 0.0069 16.9 0.4 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GARS_N PF02844.15 EGG42947.1 - 0.044 14.6 0.3 0.1 13.4 0.3 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NAD_binding_7 PF13241.6 EGG42947.1 - 0.05 14.0 0.2 0.1 13.1 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DHquinase_I PF01487.15 EGG42948.1 - 3.6e-55 187.7 0.1 4e-55 187.6 0.1 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF5619 PF18505.1 EGG42948.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) DHQS PF01959.16 EGG42949.1 - 8.2e-104 347.3 1.0 9.7e-104 347.0 1.0 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase II CppA_N PF14506.6 EGG42949.1 - 0.028 14.5 0.3 0.12 12.5 0.0 2.1 2 1 0 2 2 2 0 CppA N-terminal Orthopox_A36R PF05950.11 EGG42949.1 - 0.051 13.7 0.1 0.097 12.8 0.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Glyco_transf_41 PF13844.6 EGG42949.1 - 0.12 10.8 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 41 DeoC PF01791.9 EGG42950.1 - 1.2e-49 169.1 0.0 1.4e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Radical_SAM PF04055.21 EGG42951.1 - 6.8e-15 55.8 0.0 8.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF905 PF06006.12 EGG42951.1 - 0.13 12.2 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) UbiD PF01977.16 EGG42952.1 - 4.1e-152 506.7 0.0 4.8e-152 506.5 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF2748 PF10871.8 EGG42953.1 - 0.05 12.2 0.2 0.056 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Ribosomal_L29 PF00831.23 EGG42954.1 - 0.032 14.2 1.3 0.032 14.2 1.3 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein DUF4407 PF14362.6 EGG42954.1 - 4.6 6.5 9.2 1.8 7.8 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nitr_red_assoc PF09655.10 EGG42954.1 - 5.7 7.6 6.6 1.4 9.6 0.2 2.5 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) AhpC-TSA PF00578.21 EGG42955.1 - 5.2e-38 129.8 0.2 6e-38 129.5 0.2 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG42955.1 - 3e-26 91.9 0.1 3.4e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 EGG42955.1 - 1.6e-08 34.4 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 EGG42955.1 - 2.8e-08 33.8 0.1 4.9e-08 33.1 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 EGG42955.1 - 0.00053 19.9 0.1 0.0011 18.8 0.1 1.6 1 1 0 1 1 1 1 SCO1/SenC MIP PF00230.20 EGG42956.1 - 4.2e-54 183.7 18.6 4.9e-54 183.4 18.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ldr_toxin PF13940.6 EGG42956.1 - 0.0012 18.8 1.5 0.0042 17.1 1.5 2.0 1 0 0 1 1 1 1 Toxin Ldr, type I toxin-antitoxin system NPV_P10 PF05531.12 EGG42957.1 - 0.00067 20.1 0.9 0.00081 19.8 0.9 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 EGG42957.1 - 0.002 17.9 4.6 0.19 11.5 0.3 2.0 1 1 1 2 2 2 2 Spindle and kinetochore-associated protein 2 JIP_LZII PF16471.5 EGG42957.1 - 0.0028 17.8 7.9 0.0045 17.1 7.9 1.4 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 EGG42957.1 - 0.0052 17.0 7.7 0.0067 16.6 7.7 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding GAS PF13851.6 EGG42957.1 - 0.0091 15.4 12.0 0.011 15.1 12.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGG42957.1 - 0.011 14.7 10.0 0.014 14.3 10.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Dynamitin PF04912.14 EGG42957.1 - 0.014 14.8 6.4 0.015 14.7 6.4 1.0 1 0 0 1 1 1 0 Dynamitin ZapB PF06005.12 EGG42957.1 - 0.018 15.5 10.6 0.14 12.6 10.6 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DUF948 PF06103.11 EGG42957.1 - 0.023 14.9 1.1 0.038 14.3 0.7 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Dynactin_p22 PF07426.11 EGG42957.1 - 0.025 14.4 7.7 0.52 10.1 1.8 2.0 1 1 1 2 2 2 0 Dynactin subunit p22 BLOC1_2 PF10046.9 EGG42957.1 - 0.036 14.4 7.6 0.11 12.8 7.1 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FadA PF09403.10 EGG42957.1 - 0.037 14.5 11.7 0.05 14.1 11.5 1.4 1 1 0 1 1 1 0 Adhesion protein FadA PaaX_C PF08223.11 EGG42957.1 - 0.06 13.6 3.2 2.4 8.5 0.5 2.0 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain ABC_tran_CTD PF16326.5 EGG42957.1 - 0.063 13.5 10.2 1.1 9.6 3.0 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain CLZ PF16526.5 EGG42957.1 - 0.067 13.5 5.2 1.1 9.6 2.3 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Bap31_Bap29_C PF18035.1 EGG42957.1 - 0.07 13.1 11.8 0.52 10.4 5.5 2.2 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MtrG PF04210.13 EGG42957.1 - 0.072 13.0 3.1 0.074 12.9 1.2 1.9 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G TipAS PF07739.13 EGG42957.1 - 0.073 13.6 4.2 0.12 13.0 3.3 1.6 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain FlxA PF14282.6 EGG42957.1 - 0.077 13.0 5.2 0.087 12.8 5.2 1.1 1 0 0 1 1 1 0 FlxA-like protein Dor1 PF04124.12 EGG42957.1 - 0.14 10.8 4.8 0.16 10.6 4.8 1.1 1 0 0 1 1 1 0 Dor1-like family DUF883 PF05957.13 EGG42957.1 - 0.18 12.5 2.4 0.27 11.9 2.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4446 PF14584.6 EGG42957.1 - 0.22 11.5 7.3 0.25 11.3 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OmpH PF03938.14 EGG42957.1 - 0.25 11.7 8.9 0.26 11.6 8.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 EGG42957.1 - 0.26 10.5 6.3 0.32 10.3 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DASH_Dad3 PF08656.10 EGG42957.1 - 0.29 11.2 5.0 0.75 9.9 5.0 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad3 DUF3958 PF13125.6 EGG42957.1 - 0.4 10.9 12.5 2.2 8.5 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) DUF3245 PF11595.8 EGG42957.1 - 0.43 11.1 7.8 0.51 10.8 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) HemX PF04375.14 EGG42957.1 - 0.54 9.5 5.9 0.61 9.3 5.9 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DivIC PF04977.15 EGG42957.1 - 0.83 9.5 9.1 3.2 7.6 1.2 2.1 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 EGG42957.1 - 1.1 8.3 7.9 1.2 8.1 7.9 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EMC3_TMCO1 PF01956.16 EGG42957.1 - 1.5 8.5 7.8 1.6 8.4 7.8 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CotJB PF12652.7 EGG42957.1 - 1.6 9.0 7.5 2.7 8.3 2.1 2.1 1 1 1 2 2 2 0 CotJB protein Tho2 PF11262.8 EGG42957.1 - 2 7.6 10.5 2.1 7.4 10.5 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1640 PF07798.11 EGG42957.1 - 2.3 8.2 10.7 2.8 7.9 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1910 PF08928.10 EGG42957.1 - 2.6 8.1 8.4 31 4.6 7.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) YtxH PF12732.7 EGG42957.1 - 2.7 8.6 5.5 5.5 7.6 5.5 1.5 1 1 0 1 1 1 0 YtxH-like protein LMBR1 PF04791.16 EGG42957.1 - 4.4 6.1 4.4 5.1 5.9 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 EGG42957.1 - 6.3 5.9 8.1 7.1 5.8 8.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2951 PF11166.8 EGG42957.1 - 8.7 6.6 10.4 10 6.4 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DLH PF01738.18 EGG42958.1 - 4.9e-51 173.3 0.0 6.5e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGG42958.1 - 1.3e-06 28.1 0.0 0.024 14.1 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.11 EGG42958.1 - 1.8e-05 23.9 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.11 EGG42958.1 - 4.4e-05 23.5 0.2 0.0027 17.6 0.0 2.4 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 EGG42958.1 - 0.00012 21.8 0.1 0.00018 21.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EGG42958.1 - 0.00019 20.4 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGG42958.1 - 0.00026 20.3 0.0 0.0059 15.9 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 EGG42958.1 - 0.12 10.8 0.0 0.39 9.2 0.0 1.7 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II P5-ATPase PF12409.8 EGG42959.1 - 0.008 16.3 0.5 0.008 16.3 0.5 1.9 2 1 0 2 2 2 1 P5-type ATPase cation transporter Tox-WTIP PF15654.6 EGG42959.1 - 0.027 14.9 1.0 0.35 11.3 0.0 2.2 1 1 1 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif UMPH-1 PF05822.12 EGG42959.1 - 0.074 12.5 0.4 7.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF3021 PF11457.8 EGG42959.1 - 4.1 7.8 14.4 0.12 12.6 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) Adenine_glyco PF03352.13 EGG42960.1 - 7.4e-81 270.1 0.3 9.3e-81 269.8 0.3 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase DUF3383 PF11863.8 EGG42960.1 - 0.11 11.4 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Ferritin PF00210.24 EGG42961.1 - 5.2e-41 139.9 0.8 6.1e-41 139.7 0.8 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 EGG42961.1 - 4.5e-05 23.9 1.0 6.6e-05 23.3 1.0 1.3 1 0 0 1 1 1 1 Rubrerythrin Lipoprotein_10 PF03202.13 EGG42961.1 - 0.056 13.9 2.1 0.12 12.9 0.6 2.0 2 1 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Nuc_rec_co-act PF08815.10 EGG42961.1 - 0.2 11.5 0.2 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Nuclear receptor coactivator DUF538 PF04398.12 EGG42962.1 - 0.066 13.6 0.1 0.085 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF538 IMPa_helical PF18642.1 EGG42963.1 - 0.065 13.7 0.2 0.099 13.1 0.2 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain DUF3990 PF13151.6 EGG42964.1 - 0.068 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) MscS_porin PF12795.7 EGG42966.1 - 5.9e-06 26.0 13.4 5.9e-06 26.0 13.4 3.1 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain EzrA PF06160.12 EGG42966.1 - 0.01 14.0 44.4 0.0056 14.9 19.7 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA WEMBL PF05701.11 EGG42966.1 - 0.018 13.7 39.2 0.043 12.5 25.1 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light GBR2_CC PF18455.1 EGG42966.1 - 0.029 14.5 0.2 0.1 12.7 0.2 2.0 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain APG6_N PF17675.1 EGG42966.1 - 0.041 14.4 48.5 0.29 11.7 14.3 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF3584 PF12128.8 EGG42966.1 - 0.18 9.3 38.1 0.21 9.0 38.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IFT57 PF10498.9 EGG42966.1 - 0.23 10.4 40.5 0.21 10.5 7.6 3.2 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 HMMR_N PF15905.5 EGG42966.1 - 0.32 10.4 53.3 1.1 8.7 7.6 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TRPM_tetra PF16519.5 EGG42966.1 - 0.42 10.8 13.7 1.2 9.3 1.1 3.9 2 1 1 3 3 3 0 Tetramerisation domain of TRPM Mce4_CUP1 PF11887.8 EGG42966.1 - 0.64 9.4 3.8 1.1 8.6 0.5 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Fez1 PF06818.15 EGG42966.1 - 1.9 8.9 41.9 1.8e+03 -0.8 39.1 2.6 1 1 0 1 1 1 0 Fez1 DUF948 PF06103.11 EGG42966.1 - 2.7 8.3 18.0 0.061 13.6 1.4 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prp19 PF08606.11 EGG42966.1 - 2.9 7.9 9.2 0.82 9.7 0.2 3.7 3 2 0 3 3 3 0 Prp19/Pso4-like DUF1664 PF07889.12 EGG42966.1 - 3 7.9 29.8 3.9 7.5 5.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FH2 PF02181.23 EGG42966.1 - 3.3 6.7 33.4 0.11 11.6 4.6 3.1 1 1 2 3 3 3 0 Formin Homology 2 Domain ATG16 PF08614.11 EGG42966.1 - 3.3 7.9 42.4 6.2 7.0 12.8 3.4 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 EGG42966.1 - 3.5 7.7 39.3 2.5 8.2 9.7 3.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.11 EGG42966.1 - 4.6 7.7 38.6 0.74 10.3 2.0 5.2 2 2 4 6 6 6 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 EGG42966.1 - 5.1 7.8 43.3 1.1 10.0 7.2 3.9 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Streptin-Immun PF11083.8 EGG42966.1 - 5.4 7.5 30.2 0.47 10.9 1.8 4.4 2 1 2 4 4 4 0 Lantibiotic streptin immunity protein CC2-LZ PF16516.5 EGG42966.1 - 5.5 7.4 37.9 2.2 8.7 9.0 4.0 2 1 1 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Uso1_p115_C PF04871.13 EGG42966.1 - 5.6 7.4 50.4 0.96 9.8 16.9 3.3 1 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 EGG42966.1 - 5.8 6.9 35.1 0.88 9.6 12.4 3.2 1 1 2 3 3 3 0 Laminin Domain II TPR_MLP1_2 PF07926.12 EGG42966.1 - 7 6.7 49.8 1.9 8.5 16.5 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EGG42966.1 - 8.5 5.1 49.6 6.3 5.6 30.2 3.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DegS PF05384.11 EGG42966.1 - 9.1 5.7 40.0 6.4 6.3 5.5 3.7 1 1 2 3 3 3 0 Sensor protein DegS DUF1129 PF06570.11 EGG42967.1 - 0.16 11.5 0.7 0.18 11.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) tRNA-synt_1f PF01921.18 EGG42968.1 - 1.4e-108 363.1 0.0 4.1e-108 361.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (K) PolyA_pol_RNAbd PF12627.7 EGG42968.1 - 0.016 15.0 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A tRNA-synt_1g PF09334.11 EGG42968.1 - 0.1 11.3 0.0 0.25 10.0 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (M) Radical_SAM_C PF16199.5 EGG42969.1 - 5.6e-26 90.4 0.3 1.4e-25 89.1 0.3 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGG42969.1 - 6.5e-21 75.4 0.0 1.9e-20 73.9 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_10 PF13673.7 EGG42969.1 - 6.5e-06 26.1 0.0 2.1e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG42969.1 - 5.3e-05 23.4 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Na_H_Exchanger PF00999.21 EGG42970.1 - 8.3e-61 205.9 48.3 1.1e-60 205.5 48.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ATP19 PF11022.8 EGG42970.1 - 1.1 9.7 4.4 11 6.5 0.2 3.8 3 0 0 3 3 3 0 ATP synthase subunit K AIRS_C PF02769.22 EGG42971.1 - 1.4e-26 93.5 0.0 2.7e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EGG42971.1 - 6.7e-16 58.7 1.6 1.4e-15 57.7 1.6 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PAC2 PF09754.9 EGG42972.1 - 2.4e-30 106.2 0.0 2.7e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 PAC2 family Na_H_Exchanger PF00999.21 EGG42973.1 - 9.4e-36 123.4 46.9 1.3e-35 123.0 46.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DAP3 PF10236.9 EGG42974.1 - 0.082 12.1 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Diphthami_syn_2 PF01902.17 EGG42975.1 - 4.5e-56 189.8 0.1 5.1e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Diphthamide synthase QueC PF06508.13 EGG42975.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 EGG42975.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase SRP54 PF00448.22 EGG42976.1 - 1.1e-68 230.8 1.2 1.2e-68 230.6 0.2 1.6 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGG42976.1 - 7.4e-26 90.7 2.3 2.6e-25 88.9 0.5 2.7 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EGG42976.1 - 8.8e-17 61.1 1.6 8.8e-17 61.1 1.6 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EGG42976.1 - 1.4e-06 28.4 0.1 5.7e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EGG42976.1 - 5.9e-05 22.7 1.0 0.00017 21.2 1.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ParA PF10609.9 EGG42976.1 - 7.4e-05 22.3 0.1 0.00014 21.4 0.1 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MobB PF03205.14 EGG42976.1 - 0.00053 19.9 0.3 0.0012 18.7 0.3 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 EGG42976.1 - 0.0011 18.7 1.7 0.88 9.3 0.4 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.18 EGG42976.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.20 EGG42976.1 - 0.0015 18.5 0.4 0.003 17.4 0.1 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase KTI12 PF08433.10 EGG42976.1 - 0.0015 18.1 0.1 0.0039 16.7 0.1 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 EGG42976.1 - 0.0015 18.9 0.9 0.0041 17.6 0.1 2.1 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 EGG42976.1 - 0.0015 17.5 0.0 0.007 15.4 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EGG42976.1 - 0.0046 16.4 0.1 0.013 15.0 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Zeta_toxin PF06414.12 EGG42976.1 - 0.006 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EGG42976.1 - 0.0067 17.0 0.3 0.03 14.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG42976.1 - 0.0071 16.6 0.1 0.024 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain Thymidylate_kin PF02223.17 EGG42976.1 - 0.0079 15.9 0.4 0.023 14.4 0.4 1.8 1 0 0 1 1 1 1 Thymidylate kinase AAA_26 PF13500.6 EGG42976.1 - 0.01 15.7 0.1 2.6 7.8 1.1 2.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EGG42976.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EGG42976.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EGG42976.1 - 0.012 15.7 0.3 0.048 13.7 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 EGG42976.1 - 0.013 15.4 1.4 0.037 14.0 0.4 2.0 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGG42976.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LpxK PF02606.14 EGG42976.1 - 0.019 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_30 PF13604.6 EGG42976.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG42976.1 - 0.023 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGG42976.1 - 0.039 13.9 2.5 0.041 13.8 0.5 2.1 2 0 0 2 2 2 0 NTPase SRPRB PF09439.10 EGG42976.1 - 0.04 13.4 0.3 0.28 10.6 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TssR PF17643.1 EGG42976.1 - 0.043 11.8 0.3 0.16 9.9 0.2 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssR MipZ PF09140.11 EGG42976.1 - 0.053 12.8 0.6 2.1 7.6 0.2 2.2 1 1 1 2 2 2 0 ATPase MipZ ABC_tran PF00005.27 EGG42976.1 - 0.06 13.9 0.2 0.17 12.4 0.0 1.9 2 0 0 2 2 1 0 ABC transporter ResIII PF04851.15 EGG42976.1 - 0.074 13.0 2.4 0.19 11.7 1.3 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF4317 PF14199.6 EGG42976.1 - 0.079 12.1 0.5 7.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) SpoVIF PF14069.6 EGG42976.1 - 0.083 12.7 1.6 0.31 10.8 1.3 2.3 1 1 0 1 1 1 0 Stage VI sporulation protein F AAA PF00004.29 EGG42976.1 - 0.098 13.1 0.2 2.1 8.8 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG42976.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DLP_helical PF18709.1 EGG42976.1 - 0.12 11.6 0.6 0.42 9.8 0.6 1.9 1 0 0 1 1 1 0 Dynamin-like helical domain CLP1_P PF16575.5 EGG42976.1 - 0.16 11.7 0.2 4 7.2 0.2 2.4 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 EGG42976.1 - 0.17 12.2 0.2 0.28 11.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 EGG42976.1 - 1.2 8.2 4.3 1.8 7.7 0.5 2.8 4 0 0 4 4 3 0 Anion-transporting ATPase THUMP PF02926.17 EGG42977.1 - 4.1e-06 26.9 0.1 9.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 THUMP domain Tox-PL-2 PF15643.6 EGG42977.1 - 0.083 13.0 0.9 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 Papain fold toxin 2 SprT-like PF10263.9 EGG42978.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Ribosomal_S27 PF01599.19 EGG42980.1 - 1.4e-19 70.0 6.2 1.7e-19 69.7 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a DUF1451 PF07295.11 EGG42980.1 - 0.00028 20.9 0.8 0.00028 20.9 0.8 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain Ribosomal_L37e PF01907.19 EGG42980.1 - 0.0084 16.2 2.5 0.014 15.6 2.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e Ephrin_rec_like PF07699.13 EGG42980.1 - 0.011 15.5 1.3 0.014 15.1 1.3 1.3 1 0 0 1 1 1 0 Putative ephrin-receptor like zinc_ribbon_11 PF11682.8 EGG42980.1 - 0.04 13.9 0.8 0.042 13.9 0.1 1.5 1 1 1 2 2 2 0 Probable zinc-ribbon GFA PF04828.14 EGG42980.1 - 0.063 13.6 2.8 0.15 12.5 1.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EGG42980.1 - 0.33 10.9 5.5 1.7 8.6 3.9 2.2 1 1 1 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 EGG42980.1 - 0.45 10.0 6.6 3.2 7.3 0.5 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 EGG42980.1 - 3.4 7.3 4.9 2.9 7.6 0.3 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger Ribosomal_S24e PF01282.19 EGG42981.1 - 4.4e-07 29.8 0.3 6.2e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e GXGXG PF01493.19 EGG42981.1 - 0.064 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 GXGXG motif DUF309 PF03745.14 EGG42982.1 - 2.7e-16 59.0 0.1 4.2e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF309) DUF5355 PF17306.2 EGG42982.1 - 0.0071 15.4 0.0 0.014 14.5 0.0 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5355) PhosphMutase PF10143.9 EGG42983.1 - 7.3e-44 149.6 0.0 1.5e-43 148.6 0.0 1.5 2 0 0 2 2 2 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 EGG42983.1 - 2.4e-30 105.7 0.7 3.2e-30 105.3 0.7 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EGG42983.1 - 0.0012 18.5 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase GalP_UDP_transf PF01087.22 EGG42984.1 - 3.8e-10 40.5 0.0 9.9e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 EGG42984.1 - 0.00035 19.5 0.0 0.00074 18.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4921) HIT PF01230.23 EGG42984.1 - 0.00035 21.2 0.0 0.059 14.1 0.0 2.3 2 0 0 2 2 2 1 HIT domain GalP_UDP_tr_C PF02744.17 EGG42984.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain MFS_1 PF07690.16 EGG42985.1 - 4.6e-05 22.5 8.6 6.3e-05 22.1 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NTP_transferase PF00483.23 EGG42986.1 - 3.1e-28 99.0 0.1 3.5e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase Phos_pyr_kin PF08543.12 EGG42987.1 - 6.2e-72 241.9 0.8 1e-71 241.2 0.8 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ThiP_synth PF10120.9 EGG42987.1 - 9.7e-54 181.4 0.0 1.6e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine-phosphate synthase PfkB PF00294.24 EGG42987.1 - 1.1e-09 38.1 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HTH_56 PF18662.1 EGG42987.1 - 5.6e-06 26.4 3.4 0.0025 17.8 0.5 3.3 3 0 0 3 3 3 2 Cch helix turn helix domain Carb_kinase PF01256.17 EGG42987.1 - 0.0068 15.9 0.1 0.014 14.9 0.1 1.5 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EGG42987.1 - 0.022 14.2 0.2 0.044 13.2 0.2 1.5 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family DUF2111 PF09884.9 EGG42987.1 - 0.059 13.4 0.2 0.18 11.9 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) ThiC_Rad_SAM PF01964.18 EGG42988.1 - 5e-172 572.4 0.2 5.8e-172 572.2 0.2 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family NUDIX PF00293.28 EGG42989.1 - 3.4e-11 43.3 0.0 3.8e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGG42989.1 - 0.0012 18.8 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Protamine_like PF06382.11 EGG42989.1 - 0.025 14.7 0.1 0.033 14.4 0.1 1.1 1 0 0 1 1 1 0 Protamine and protamine like PDH PF02153.17 EGG42990.1 - 7.6e-25 87.4 0.3 8.9e-25 87.1 0.3 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 EGG42990.1 - 5e-06 26.0 0.1 9.2e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGG42990.1 - 1.6e-05 25.1 0.1 6e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG42990.1 - 0.00012 22.6 1.4 0.0012 19.3 0.0 3.2 3 2 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EGG42990.1 - 0.00036 20.5 0.3 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGG42990.1 - 0.01 15.8 0.8 9 6.2 0.0 3.1 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DpaA_N PF16924.5 EGG42990.1 - 0.027 14.6 0.2 0.17 11.9 0.0 2.4 2 2 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain NmrA PF05368.13 EGG42990.1 - 0.031 13.8 0.8 1.2 8.6 0.1 2.6 3 0 0 3 3 3 0 NmrA-like family Semialdhyde_dh PF01118.24 EGG42990.1 - 0.063 13.7 0.0 4.8 7.6 0.0 2.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.12 EGG42990.1 - 0.066 12.8 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1392 PF07154.11 EGG42990.1 - 0.1 12.7 0.1 0.29 11.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1392) DUF3040 PF11239.8 EGG42992.1 - 0.06 13.6 0.3 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Saf_2TM PF18303.1 EGG42992.1 - 0.077 12.6 1.2 0.085 12.5 0.1 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain YtpI PF14007.6 EGG42992.1 - 0.094 12.9 0.9 0.094 12.9 0.9 2.0 2 0 0 2 2 2 0 YtpI-like protein DUF202 PF02656.15 EGG42992.1 - 0.23 11.9 0.7 1.6 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) tRNA_anti-codon PF01336.25 EGG42993.1 - 6.1e-06 26.1 0.3 7.8e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 EGG42993.1 - 6.4e-05 22.8 0.8 7.2e-05 22.6 0.8 1.1 1 0 0 1 1 1 1 Replication protein A OB domain HupF_HypC PF01455.18 EGG42993.1 - 0.032 14.4 0.7 4.3 7.6 0.4 2.1 1 1 1 2 2 2 0 HupF/HypC family DUF713 PF05218.14 EGG42994.1 - 0.0026 17.5 5.7 0.0033 17.2 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF713) Pox_A12 PF04651.13 EGG42994.1 - 0.0075 16.3 3.8 0.0092 16.1 3.8 1.2 1 0 0 1 1 1 1 Poxvirus A12 protein DUF4290 PF14123.6 EGG42994.1 - 0.011 15.3 1.3 0.017 14.6 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4290) DUF4745 PF15923.5 EGG42994.1 - 0.013 15.5 3.1 0.023 14.7 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4745) Lipoprotein_6 PF01441.19 EGG42994.1 - 0.014 15.4 1.7 0.017 15.1 1.7 1.1 1 0 0 1 1 1 0 Lipoprotein BORCS6 PF10157.9 EGG42994.1 - 0.02 15.1 1.0 1.3 9.3 0.0 2.3 1 1 0 2 2 2 0 BLOC-1-related complex sub-unit 6 HEPN_RiboL-PSP PF18735.1 EGG42994.1 - 0.02 14.8 1.5 0.042 13.8 1.5 1.4 1 1 0 1 1 1 0 RiboL-PSP-HEPN AATF-Che1 PF13339.6 EGG42994.1 - 0.022 15.5 3.2 0.041 14.6 3.2 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Mod_r PF07200.13 EGG42994.1 - 0.031 14.4 1.1 0.05 13.7 1.1 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YojJ PF10372.9 EGG42994.1 - 0.031 14.3 0.1 0.11 12.6 0.0 2.0 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Tape_meas_lam_C PF09718.10 EGG42994.1 - 0.12 12.5 4.6 1.7 8.8 0.1 2.5 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF2232 PF09991.9 EGG42994.1 - 0.23 10.6 0.8 0.33 10.1 0.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Fib_alpha PF08702.10 EGG42994.1 - 1.4 9.1 10.2 1.4 9.1 2.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HD PF01966.22 EGG42996.1 - 2.6e-16 60.0 0.1 3.6e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 HD domain DUF4917 PF16263.5 EGG42996.1 - 0.027 13.8 0.5 0.056 12.8 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4917) MMACHC PF16690.5 EGG42996.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family ClpS PF02617.17 EGG42996.1 - 0.096 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Bac_RepA_C PF18008.1 EGG42996.1 - 0.34 11.3 3.8 6.4 7.2 0.0 2.5 3 0 0 3 3 3 0 Replication initiator protein A C-terminal domain zf-FCS PF06467.14 EGG42997.1 - 0.14 12.1 5.7 2.3 8.2 0.1 2.7 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif TFIIB PF00382.19 EGG42998.1 - 5.4e-23 80.8 2.1 3.7e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Rrf2 PF02082.20 EGG42998.1 - 0.003 17.9 0.8 2.7 8.4 0.0 3.1 2 1 1 3 3 3 2 Transcriptional regulator TF_Zn_Ribbon PF08271.12 EGG42998.1 - 0.0063 16.0 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding KIAA1430 PF13879.6 EGG42998.1 - 0.011 16.4 0.4 0.94 10.3 0.0 2.3 2 0 0 2 2 2 0 KIAA1430 homologue Cyclin_C PF02984.19 EGG42998.1 - 0.062 13.4 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Cyclin, C-terminal domain Pyridox_ox_2 PF12900.7 EGG42999.1 - 1.1e-06 28.8 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EGG42999.1 - 7.5e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EGG42999.1 - 0.033 13.8 0.0 0.059 12.9 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Amino_oxidase PF01593.24 EGG43002.1 - 3.1e-23 82.8 0.0 4.3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG43002.1 - 9.6e-14 51.4 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG43002.1 - 9.8e-07 28.7 0.0 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG43002.1 - 4.6e-05 22.8 0.2 0.01 15.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG43002.1 - 0.0002 21.8 0.8 0.06 13.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG43002.1 - 0.00043 19.6 0.6 0.022 14.0 0.1 2.5 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 EGG43002.1 - 0.00072 18.4 0.1 0.23 10.1 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EGG43002.1 - 0.00077 18.6 0.2 0.043 12.9 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain MCRA PF06100.11 EGG43002.1 - 0.0018 17.1 0.1 1.5 7.5 0.0 2.3 2 0 0 2 2 2 2 MCRA family FAD_oxidored PF12831.7 EGG43002.1 - 0.0032 16.9 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EGG43002.1 - 0.012 14.8 0.7 2.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGG43002.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EGG43002.1 - 0.11 12.1 0.4 0.36 10.4 0.1 2.0 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 EGG43002.1 - 0.21 11.5 0.0 0.48 10.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding B12-binding PF02310.19 EGG43003.1 - 5.3e-13 49.1 0.0 9.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 EGG43003.1 - 2.9e-09 37.2 0.0 5.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain NAD_binding_10 PF13460.6 EGG43004.1 - 2e-16 60.4 0.0 3.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGG43004.1 - 3e-12 46.5 0.0 3.9e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGG43004.1 - 8.7e-11 41.8 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EGG43004.1 - 6.3e-09 35.2 0.0 1.5e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG43004.1 - 0.00012 21.7 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGG43004.1 - 0.0022 17.1 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGG43004.1 - 0.017 14.3 0.1 0.056 12.6 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 EGG43004.1 - 0.045 12.9 0.8 0.33 10.0 0.8 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EGG43004.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_7 PF03441.14 EGG43005.1 - 1.5e-79 266.1 2.4 2.3e-79 265.6 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGG43005.1 - 8.6e-36 123.4 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase OprF PF05736.11 EGG43005.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 OprF membrane domain DUF1722 PF08349.11 EGG43006.1 - 7.7e-33 113.3 1.4 8.7e-33 113.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) Dioxygenase_N PF04444.14 EGG43007.1 - 0.028 14.3 0.2 7.9 6.4 0.1 2.5 2 0 0 2 2 2 0 Catechol dioxygenase N terminus EF-hand_1 PF00036.32 EGG43007.1 - 0.036 13.6 0.1 11 5.9 0.1 2.6 2 0 0 2 2 2 0 EF hand DUF1372 PF07116.11 EGG43007.1 - 0.07 13.3 0.2 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) SHOCT PF09851.9 EGG43007.1 - 0.2 11.4 0.9 15 5.5 0.0 3.0 3 0 0 3 3 3 0 Short C-terminal domain DUF1896 PF08989.10 EGG43008.1 - 0.021 14.9 0.6 0.026 14.6 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1896) DUF2833 PF11090.8 EGG43008.1 - 0.027 14.8 2.2 0.034 14.5 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2833) IMS PF00817.20 EGG43008.1 - 0.03 14.3 0.1 0.03 14.3 0.1 1.1 1 0 0 1 1 1 0 impB/mucB/samB family JmjN PF02375.17 EGG43008.1 - 0.17 11.8 2.7 1 9.4 0.2 2.4 1 1 1 2 2 2 0 jmjN domain ALAD PF00490.21 EGG43009.1 - 3.5e-137 456.8 1.2 3.9e-137 456.6 1.2 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase GlutR_N PF05201.15 EGG43010.1 - 3.8e-37 127.3 0.1 1e-36 125.9 0.1 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EGG43010.1 - 1.1e-29 103.3 0.6 2e-29 102.4 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EGG43010.1 - 8.8e-18 64.6 1.6 2.4e-17 63.2 1.6 1.8 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 EGG43010.1 - 4.2e-05 24.0 0.0 0.00014 22.4 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGG43010.1 - 0.0011 18.4 0.0 0.0048 16.3 0.0 1.9 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGG43010.1 - 0.029 14.6 0.2 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAM25 PF15825.5 EGG43010.1 - 0.033 14.5 2.4 0.042 14.2 0.3 2.4 2 0 0 2 2 2 0 FAM25 family Malic_M PF03949.15 EGG43010.1 - 0.034 13.4 0.1 0.25 10.6 0.0 2.1 1 1 1 2 2 2 0 Malic enzyme, NAD binding domain Mt_ATP-synt_D PF05873.12 EGG43010.1 - 0.056 13.3 1.7 0.17 11.7 1.7 1.8 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Methyltransf_31 PF13847.6 EGG43010.1 - 0.076 12.8 0.0 0.34 10.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain VP9 PF09625.10 EGG43010.1 - 0.079 13.1 0.6 3.1 8.0 0.2 2.7 2 0 0 2 2 2 0 VP9 protein DUF4535 PF15054.6 EGG43010.1 - 1.3 8.8 0.0 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) ACPS PF01648.20 EGG43011.1 - 0.035 14.2 1.1 0.78 9.9 1.1 2.0 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DUF2815 PF10991.8 EGG43011.1 - 0.12 12.3 3.8 0.14 12.1 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) APT PF03440.14 EGG43011.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Cas_Csa5 PF09702.10 EGG43011.1 - 0.16 12.2 2.2 0.19 12.0 2.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) AsnC_trans_reg2 PF17805.1 EGG43012.1 - 2.8e-53 178.0 0.0 1.4e-29 102.1 0.0 3.0 3 0 0 3 3 3 2 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 EGG43012.1 - 0.00053 19.8 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain C5HCH PF17982.1 EGG43013.1 - 0.073 13.2 0.9 0.12 12.5 0.9 1.4 1 0 0 1 1 1 0 NSD Cys-His rich domain Aldo_ket_red PF00248.21 EGG43014.1 - 8.8e-55 186.0 0.1 9.9e-55 185.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Chlor_dismutase PF06778.12 EGG43015.1 - 1e-54 185.1 0.1 1.3e-54 184.8 0.1 1.1 1 0 0 1 1 1 1 Chlorite dismutase NHL PF01436.21 EGG43016.1 - 4.6e-56 184.2 17.7 1.2e-09 37.7 0.1 6.5 6 0 0 6 6 6 6 NHL repeat HemolysinCabind PF00353.19 EGG43016.1 - 1.7e-34 117.4 100.3 4.9e-10 39.2 14.4 7.3 4 1 2 8 8 8 5 RTX calcium-binding nonapeptide repeat (4 copies) SGL PF08450.12 EGG43016.1 - 3.3e-18 66.2 10.6 6.9e-09 35.6 1.7 4.3 1 1 3 4 4 4 4 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 EGG43016.1 - 9.4e-16 57.5 25.5 0.025 14.6 0.2 7.6 6 0 0 6 6 6 6 Beta-propeller repeat DUF5128 PF17170.4 EGG43016.1 - 7.8e-14 51.6 15.0 4.9e-05 22.6 0.6 4.5 2 1 1 4 4 4 4 6-bladed beta-propeller Phytase-like PF13449.6 EGG43016.1 - 6e-11 42.8 2.8 0.069 13.1 0.0 5.2 2 2 2 5 5 5 3 Esterase-like activity of phytase Arylesterase PF01731.20 EGG43016.1 - 4.6e-08 33.2 2.4 0.13 12.5 0.0 5.4 4 2 2 6 6 6 2 Arylesterase SdiA-regulated PF06977.11 EGG43016.1 - 9e-05 21.8 1.6 4 6.6 0.0 4.8 4 1 1 5 5 5 2 SdiA-regulated ThiC-associated PF13667.6 EGG43016.1 - 0.00018 21.2 3.2 26 4.7 0.0 5.3 4 1 1 5 5 5 0 ThiC-associated domain CUB_2 PF02408.20 EGG43016.1 - 0.027 14.3 0.2 13 5.5 0.0 3.9 2 2 3 5 5 5 0 CUB-like domain DUF2251 PF10008.9 EGG43016.1 - 0.036 14.2 6.0 79 3.5 0.0 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2251) DUF859 PF05895.12 EGG43016.1 - 0.42 9.0 10.9 2.2 6.7 0.2 4.3 1 1 1 5 5 5 0 Siphovirus protein of unknown function (DUF859) AAA_21 PF13304.6 EGG43017.1 - 5.2e-05 23.2 0.0 6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG43017.1 - 6.4e-05 22.5 0.1 7.9e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain FR47 PF08445.10 EGG43017.1 - 0.082 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein ABC_tran PF00005.27 EGG43018.1 - 1e-11 45.5 0.0 1.3e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGG43018.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EGG43018.1 - 0.00068 19.8 0.0 0.00073 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 EGG43018.1 - 0.0045 16.6 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGG43018.1 - 0.0046 16.5 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGG43018.1 - 0.0051 16.6 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG43018.1 - 0.0058 16.1 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGG43018.1 - 0.012 16.1 0.2 0.019 15.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG43018.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGG43018.1 - 0.022 14.7 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGG43018.1 - 0.023 15.1 0.1 0.055 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGG43018.1 - 0.048 14.2 0.0 0.072 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG43018.1 - 0.051 13.9 0.0 0.065 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGG43018.1 - 0.061 13.4 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG43018.1 - 0.072 13.3 0.0 0.094 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG43018.1 - 0.077 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGG43018.1 - 0.08 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EGG43018.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 EGG43018.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGG43018.1 - 0.15 11.7 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 EGG43018.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase MeaB PF03308.16 EGG43018.1 - 0.18 10.8 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TFIIB PF00382.19 EGG43019.1 - 9.1e-25 86.5 2.3 2.1e-12 46.9 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG43019.1 - 6.5e-09 35.2 1.2 6.5e-09 35.2 1.2 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RPA_interact_C PF14768.6 EGG43019.1 - 0.014 15.9 2.2 1.1 9.9 2.2 2.8 1 1 0 1 1 1 0 Replication protein A interacting C-terminal Auto_anti-p27 PF06677.12 EGG43019.1 - 0.05 13.8 0.4 0.05 13.8 0.4 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2318 PF10080.9 EGG43019.1 - 0.1 12.7 4.1 6.1 7.0 0.2 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zinc-ribbons_6 PF07191.12 EGG43019.1 - 0.33 11.0 3.8 1 9.4 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 EGG43019.1 - 0.54 10.3 4.1 0.31 11.1 0.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon Gar1 PF04410.14 EGG43020.1 - 3.7e-06 26.8 0.0 4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SRP19 PF01922.17 EGG43021.1 - 2.7e-13 50.7 0.1 3.6e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 SRP19 protein Ribosomal_S8e PF01201.22 EGG43022.1 - 3.4e-23 82.3 5.2 4e-23 82.1 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMC_ScpB PF04079.16 EGG43023.1 - 8.5e-36 123.0 0.6 1e-35 122.7 0.6 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB PadR PF03551.14 EGG43023.1 - 0.027 14.4 0.4 0.91 9.5 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HHH_3 PF12836.7 EGG43023.1 - 0.041 14.1 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HTH_20 PF12840.7 EGG43023.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain SMC_ScpA PF02616.14 EGG43024.1 - 1.8e-06 28.1 1.2 0.015 15.3 0.0 2.1 2 0 0 2 2 2 2 Segregation and condensation protein ScpA ADH_N PF08240.12 EGG43025.1 - 1e-33 115.5 0.9 1.7e-33 114.8 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG43025.1 - 1.3e-27 96.4 0.2 2.1e-27 95.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG43025.1 - 5.1e-13 50.2 0.0 7.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGG43025.1 - 3.7e-08 33.1 0.0 8.8e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus PglD_N PF17836.1 EGG43025.1 - 0.002 18.7 2.1 0.0042 17.7 2.1 1.6 1 0 0 1 1 1 1 PglD N-terminal domain AlaDh_PNT_C PF01262.21 EGG43025.1 - 0.0076 15.6 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGG43025.1 - 0.019 15.2 0.2 0.039 14.2 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.20 EGG43025.1 - 0.032 14.4 0.3 0.06 13.5 0.3 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Response_reg PF00072.24 EGG43026.1 - 3.7e-18 65.7 0.6 5.6e-18 65.2 0.6 1.3 1 0 0 1 1 1 1 Response regulator receiver domain TPR_2 PF07719.17 EGG43026.1 - 0.004 17.2 0.1 0.19 11.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Rhodanese PF00581.20 EGG43026.1 - 0.027 15.0 0.0 0.16 12.5 0.0 2.2 2 1 0 2 2 2 0 Rhodanese-like domain TPR_1 PF00515.28 EGG43026.1 - 0.029 14.2 0.0 0.093 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat PK_C PF02887.16 EGG43026.1 - 0.038 14.2 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain TPR_8 PF13181.6 EGG43026.1 - 0.064 13.5 1.4 0.32 11.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPALS PF18178.1 EGG43026.1 - 0.092 12.2 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family TPR_6 PF13174.6 EGG43026.1 - 0.12 13.0 0.2 5.4 7.9 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat NFACT-R_2 PF18297.1 EGG43026.1 - 0.13 12.5 0.9 0.82 9.9 0.1 2.4 3 0 0 3 3 3 0 NFACT protein RNA binding domain SMC_N PF02463.19 EGG43026.1 - 0.27 10.6 1.3 0.46 9.9 0.6 2.0 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain fn3 PF00041.21 EGG43027.1 - 0.00034 20.9 0.4 0.0008 19.7 0.2 1.6 2 0 0 2 2 2 1 Fibronectin type III domain DUF1411 PF07199.11 EGG43027.1 - 0.064 12.9 0.2 0.15 11.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1411) Virul_fac_BrkB PF03631.15 EGG43028.1 - 0.061 12.9 1.4 0.091 12.4 1.4 1.1 1 0 0 1 1 1 0 Virulence factor BrkB HTH_24 PF13412.6 EGG43029.1 - 7.6e-10 38.2 2.0 4.4e-05 23.0 0.2 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EGG43029.1 - 1.9e-09 37.2 1.5 1.4e-08 34.4 0.9 2.5 2 1 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_12 PF08461.10 EGG43029.1 - 1.9e-07 30.9 0.9 2.9e-07 30.3 0.3 1.6 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_11 PF08279.12 EGG43029.1 - 1.4e-06 28.2 0.6 5.8e-06 26.1 0.6 2.1 1 1 0 1 1 1 1 HTH domain Penicillinase_R PF03965.16 EGG43029.1 - 6.8e-05 23.2 0.3 0.00036 20.8 0.0 2.0 2 0 0 2 2 2 1 Penicillinase repressor HTH_Tnp_Tc3_2 PF01498.18 EGG43029.1 - 0.00013 22.1 1.5 0.00021 21.5 0.1 2.0 3 0 0 3 3 3 1 Transposase HTH_20 PF12840.7 EGG43029.1 - 0.00017 21.6 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 EGG43029.1 - 0.003 17.3 0.1 0.011 15.5 0.1 2.0 1 1 0 1 1 1 1 DeoR-like helix-turn-helix domain Myb_DNA-bind_4 PF13837.6 EGG43029.1 - 0.011 16.0 0.1 0.028 14.8 0.0 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3658 PF12395.8 EGG43029.1 - 0.016 15.1 0.3 0.047 13.6 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function HTH_32 PF13565.6 EGG43029.1 - 0.021 15.4 0.0 0.04 14.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain FUR PF01475.19 EGG43029.1 - 0.026 14.7 0.1 0.056 13.6 0.0 1.5 2 0 0 2 2 2 0 Ferric uptake regulator family Arg_repressor PF01316.21 EGG43029.1 - 0.04 13.7 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain RNA_binding PF01877.17 EGG43029.1 - 0.042 14.1 2.0 0.084 13.2 0.4 1.9 2 0 0 2 2 2 0 RNA binding Nuc_N PF14448.6 EGG43029.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Nuclease N terminal DUF3783 PF12646.7 EGG43029.1 - 0.053 13.5 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) HU-DNA_bdg PF14848.6 EGG43029.1 - 0.067 13.2 2.4 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 DNA-binding domain Sigma70_r4_2 PF08281.12 EGG43029.1 - 0.08 12.6 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 PepSY_like PF11396.8 EGG43029.1 - 9.5 6.8 8.3 4.8 7.8 1.0 2.9 1 1 2 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like CxxCxxCC PF03692.15 EGG43030.1 - 3.8e-10 40.3 0.2 8.6e-10 39.2 0.2 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain eIF-1a PF01176.19 EGG43031.1 - 4.6e-19 68.0 1.7 6.2e-19 67.6 1.7 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myosin_N PF02736.19 EGG43031.1 - 0.011 15.6 1.2 0.63 9.9 0.1 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain CSD PF00313.22 EGG43032.1 - 2.1e-21 75.6 3.4 2.5e-21 75.3 3.4 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EGG43032.1 - 2.2e-06 27.3 0.7 2.2e-06 27.2 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease B OB domain eIF-5a PF01287.20 EGG43034.1 - 3e-07 30.4 0.8 4.3e-07 29.9 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGG43034.1 - 5.8e-05 23.0 0.1 0.0089 16.0 0.0 2.3 2 0 0 2 2 2 2 Elongation factor P (EF-P) KOW-like domain CBS PF00571.28 EGG43035.1 - 9.2e-08 32.4 2.1 0.065 13.7 0.0 4.2 4 1 0 4 4 4 3 CBS domain DUF5049 PF16468.5 EGG43035.1 - 0.088 12.7 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) CorA PF01544.18 EGG43036.1 - 5e-70 236.1 5.2 5e-70 236.1 5.2 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Tetraspanin PF00335.20 EGG43036.1 - 0.014 15.2 1.2 0.014 15.2 1.2 2.4 2 0 0 2 2 2 0 Tetraspanin family Herpes_UL92 PF03048.14 EGG43036.1 - 0.031 14.1 2.7 0.035 13.9 0.3 2.3 2 1 0 2 2 2 0 UL92 family T2SSF PF00482.23 EGG43036.1 - 0.58 10.1 0.0 0.58 10.1 0.0 3.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F PX PF00787.24 EGG43037.1 - 0.093 12.7 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 PX domain FCH PF00611.23 EGG43038.1 - 0.015 15.5 4.1 0.022 15.0 4.1 1.2 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain APG5 PF04106.12 EGG43038.1 - 0.03 13.9 3.1 0.031 13.9 3.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg5 Aminotran_1_2 PF00155.21 EGG43040.1 - 1.4e-40 139.7 0.0 1.7e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II S-layer PF07752.11 EGG43040.1 - 0.044 12.8 0.1 0.091 11.8 0.1 1.5 1 0 0 1 1 1 0 S-layer protein Spore_III_AF PF09581.10 EGG43041.1 - 0.00025 21.1 0.9 0.00037 20.6 0.9 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) Phlebovirus_NSM PF07246.11 EGG43041.1 - 0.055 12.8 1.2 0.075 12.4 1.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M BAAT_C PF08840.11 EGG43041.1 - 0.17 11.8 0.2 0.23 11.3 0.2 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Methyltransf_21 PF05050.12 EGG43042.1 - 1.9e-14 54.1 0.2 3.3e-14 53.3 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_31 PF13847.6 EGG43042.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGG43042.1 - 0.0046 16.7 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EGG43042.1 - 0.0067 16.2 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGG43042.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EGG43042.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGG43042.1 - 0.083 13.6 0.0 0.3 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 EGG43042.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase HEAT_2 PF13646.6 EGG43044.1 - 1.3e-07 31.9 0.1 4.9e-06 26.9 0.0 2.7 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 EGG43044.1 - 0.065 13.5 0.1 21 5.7 0.0 3.2 4 0 0 4 4 4 0 HEAT repeat COQ9 PF08511.11 EGG43044.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 COQ9 TrmB PF01978.19 EGG43045.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Response_reg PF00072.24 EGG43046.1 - 1.1e-24 86.8 0.4 1.2e-24 86.6 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain 2-Hacid_dh_C PF02826.19 EGG43046.1 - 0.024 14.0 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1647 PF07801.11 EGG43046.1 - 0.14 12.0 0.1 0.18 11.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) EamA PF00892.20 EGG43047.1 - 3.1e-33 114.9 30.3 1.7e-17 63.9 16.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGG43047.1 - 2.1e-05 24.0 18.3 0.0015 18.0 6.8 2.1 1 1 1 2 2 2 2 Triose-phosphate Transporter family TMEM234 PF10639.9 EGG43047.1 - 0.08 13.0 0.5 0.08 13.0 0.5 2.5 2 1 0 2 2 2 0 Putative transmembrane family 234 DUF3290 PF11694.8 EGG43047.1 - 0.46 10.4 7.1 12 5.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) Thioredoxin_4 PF13462.6 EGG43048.1 - 3.1e-34 118.6 0.0 3.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EGG43048.1 - 4.2e-12 46.2 0.0 8.1e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EGG43048.1 - 6.9e-09 36.1 0.0 1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 EGG43048.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG43048.1 - 0.031 14.6 0.1 8.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Peptidase_S24 PF00717.23 EGG43051.1 - 5.2e-08 32.7 0.5 6.6e-08 32.4 0.5 1.2 1 0 0 1 1 1 1 Peptidase S24-like DUF4282 PF14110.6 EGG43052.1 - 0.012 16.4 0.4 0.017 15.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Pho88 PF10032.9 EGG43052.1 - 0.022 14.0 1.1 0.027 13.7 0.2 1.6 1 1 1 2 2 2 0 Phosphate transport (Pho88) DUF3810 PF12725.7 EGG43052.1 - 0.11 11.9 0.6 0.12 11.7 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Sar8_2 PF03058.14 EGG43053.1 - 0.07 13.7 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Sar8.2 family DciA PF05258.12 EGG43053.1 - 0.21 12.0 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA DUF4352 PF11611.8 EGG43054.1 - 0.023 15.0 0.3 0.031 14.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) DUF4179 PF13786.6 EGG43055.1 - 0.075 13.5 3.5 0.09 13.3 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Baculo_PEP_C PF04513.12 EGG43056.1 - 0.068 13.2 6.8 0.06 13.4 4.3 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 EGG43056.1 - 1.2 9.5 20.6 2.3 8.6 20.6 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DZF PF07528.14 EGG43056.1 - 5.2 6.6 7.7 9.1 5.8 6.3 1.8 1 1 1 2 2 2 0 DZF domain GTP-bdg_M PF16360.5 EGG43056.1 - 8 7.1 16.8 7.1 7.3 0.9 3.2 1 1 2 3 3 3 0 GTP-binding GTPase Middle Region TPR_1 PF00515.28 EGG43059.1 - 1.3e-16 59.6 1.0 4e-07 29.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG43059.1 - 5e-15 54.4 1.0 4e-08 32.8 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG43059.1 - 5.9e-15 54.1 0.4 7.2e-07 28.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG43059.1 - 6.3e-11 42.6 0.1 1.3e-07 32.0 0.0 2.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG43059.1 - 2.9e-10 39.8 0.3 0.0051 17.1 0.1 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG43059.1 - 7.4e-09 35.7 0.0 0.0084 16.9 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG43059.1 - 2.4e-08 33.4 0.0 0.013 15.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG43059.1 - 1.5e-07 31.6 0.1 2.6e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGG43059.1 - 1.9e-07 30.6 0.2 0.016 14.9 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 EGG43059.1 - 7.3e-06 26.2 0.0 0.00015 21.9 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG43059.1 - 5.3e-05 23.6 0.1 0.6 10.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG43059.1 - 7.6e-05 22.7 1.7 0.029 14.5 0.1 3.2 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 EGG43059.1 - 0.00011 21.5 0.0 0.00017 20.9 0.0 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat ChAPs PF09295.10 EGG43059.1 - 0.00019 20.5 0.1 0.00023 20.3 0.1 1.0 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 EGG43059.1 - 0.0069 15.3 0.4 0.13 11.2 0.0 1.9 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 EGG43059.1 - 0.012 16.3 0.0 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 EGG43059.1 - 0.018 15.0 0.5 0.072 13.0 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) TPR_9 PF13371.6 EGG43059.1 - 0.14 12.4 0.0 7.2 6.8 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.16 EGG43060.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain F420H2_quin_red PF04075.14 EGG43062.1 - 3.6e-06 27.1 0.0 4.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 EGG43062.1 - 0.045 13.9 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) PRC PF05239.16 EGG43063.1 - 6.4e-12 45.4 1.9 6.2e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain DUF2171 PF09939.9 EGG43063.1 - 8.9e-06 25.9 4.7 0.023 14.9 2.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2171) GTP_EFTU_D4 PF14578.6 EGG43063.1 - 0.0068 16.3 1.4 0.62 10.0 0.1 2.6 2 1 0 2 2 2 2 Elongation factor Tu domain 4 ABC_tran PF00005.27 EGG43064.1 - 1.3e-30 106.7 0.3 2.8e-30 105.6 0.0 1.7 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGG43064.1 - 6.4e-10 39.3 5.5 7.3e-07 29.3 0.1 2.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EGG43064.1 - 2.3e-08 34.6 0.8 5.7e-08 33.4 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EGG43064.1 - 0.0017 18.1 5.4 0.16 11.7 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGG43064.1 - 0.0022 17.7 0.3 0.0053 16.5 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EGG43064.1 - 0.0064 16.4 0.2 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 EGG43064.1 - 0.0092 16.5 2.8 0.0092 16.5 2.8 2.9 1 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGG43064.1 - 0.016 14.7 1.4 0.15 11.5 0.5 2.4 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EGG43064.1 - 0.037 13.5 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 EGG43064.1 - 0.1 12.2 0.3 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 EGG43065.1 - 6.2e-34 117.3 18.1 6.2e-34 117.3 18.1 1.9 1 1 1 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EGG43065.1 - 1.9e-14 53.5 29.5 2.3e-14 53.3 29.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EGG43065.1 - 3.7e-05 23.1 25.0 0.00036 19.9 25.0 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein MIP PF00230.20 EGG43066.1 - 1.2e-37 129.9 21.4 1.4e-37 129.6 21.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Aminotran_3 PF00202.21 EGG43067.1 - 6.4e-74 249.0 0.0 7.8e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG43067.1 - 4.5e-06 26.1 0.0 6.8e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II RasGAP_C PF03836.15 EGG43067.1 - 0.028 14.6 0.3 0.078 13.1 0.2 1.8 2 0 0 2 2 2 0 RasGAP C-terminus Porphobil_deam PF01379.20 EGG43068.1 - 4e-66 222.4 0.2 5.7e-66 221.9 0.2 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGG43068.1 - 2e-11 44.1 0.0 4.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TP_methylase PF00590.20 EGG43069.1 - 5.3e-51 173.6 0.0 6.1e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HEM4 PF02602.15 EGG43070.1 - 1.1e-44 152.6 0.0 1.2e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CTP_transf_like PF01467.26 EGG43070.1 - 0.035 14.3 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase-like PGM_PMM_II PF02879.16 EGG43070.1 - 0.16 12.6 0.0 0.38 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Big_9 PF17963.1 EGG43071.1 - 3.7e-13 50.0 55.8 6.1e-08 33.3 4.0 7.6 7 0 0 7 7 7 5 Bacterial Ig domain Cadherin_5 PF17892.1 EGG43071.1 - 4.6e-06 26.5 21.7 0.051 13.6 0.2 5.7 5 0 0 5 5 5 4 Cadherin-like domain PKD PF00801.20 EGG43071.1 - 4.9e-05 23.1 25.1 3 7.8 0.2 8.7 8 2 0 8 8 8 4 PKD domain Cadherin_4 PF17803.1 EGG43071.1 - 0.00061 20.4 5.5 0.00061 20.4 5.5 7.1 6 2 0 6 6 6 2 Bacterial cadherin-like domain Ig_2 PF13895.6 EGG43071.1 - 0.0016 18.7 4.7 0.17 12.2 0.1 4.4 5 0 0 5 5 5 1 Immunoglobulin domain DUF824 PF05688.11 EGG43071.1 - 0.019 14.8 6.8 3.1 7.7 0.2 4.8 4 0 0 4 4 4 0 Salmonella repeat of unknown function (DUF824) Fn3-like PF14310.6 EGG43071.1 - 0.16 12.1 0.5 4.4 7.5 0.0 3.3 3 0 0 3 3 3 0 Fibronectin type III-like domain MFS_1 PF07690.16 EGG43073.1 - 1.5e-26 93.1 32.8 4.4e-20 71.9 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGG43073.1 - 2.9e-05 23.1 24.1 0.00029 19.8 24.1 2.1 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 EGG43073.1 - 0.00038 19.0 15.0 0.0028 16.1 5.8 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector BIV_Env PF05858.12 EGG43073.1 - 0.081 11.1 1.1 3 5.9 0.0 2.1 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) Sugar_tr PF00083.24 EGG43073.1 - 0.14 10.9 26.8 0.28 10.0 13.7 3.0 1 1 2 3 3 3 0 Sugar (and other) transporter CrgA PF06781.12 EGG43073.1 - 0.44 10.7 5.6 0.57 10.3 0.0 3.6 4 0 0 4 4 4 0 Cell division protein CrgA UCR_UQCRX_QCR9 PF05365.12 EGG43073.1 - 0.77 9.8 6.3 17 5.5 0.1 3.7 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like TMEM238 PF15125.6 EGG43074.1 - 1.3 9.3 8.3 6.6 7.0 2.6 2.1 2 0 0 2 2 2 0 TMEM238 protein family CrgA PF06781.12 EGG43074.1 - 3.4 7.8 6.0 19 5.4 6.0 1.9 1 1 0 1 1 1 0 Cell division protein CrgA DUF2721 PF11026.8 EGG43074.1 - 8 6.4 7.7 17 5.3 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF1059 PF06348.11 EGG43075.1 - 2e-19 69.5 1.2 2.2e-19 69.4 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) Sina PF03145.16 EGG43075.1 - 0.044 13.7 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 Seven in absentia protein family Tnp_22_trimer PF17489.2 EGG43075.1 - 0.071 13.1 0.5 0.099 12.6 0.5 1.2 1 0 0 1 1 1 0 L1 transposable element trimerization domain E1-E2_ATPase PF00122.20 EGG43076.1 - 0.11 12.0 0.8 0.13 11.8 0.8 1.0 1 0 0 1 1 1 0 E1-E2 ATPase DUF2207 PF09972.9 EGG43076.1 - 0.15 10.8 0.3 0.16 10.7 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AcrZ PF10766.9 EGG43076.1 - 9.7 5.8 7.2 0.31 10.6 1.2 1.5 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ UPF0051 PF01458.17 EGG43077.1 - 1.6e-72 243.8 0.1 2.1e-72 243.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.17 EGG43078.1 - 7.6e-63 212.1 0.9 1e-62 211.7 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) THF_DHG_CYH_C PF02882.19 EGG43078.1 - 0.057 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2152 PF10222.9 EGG43078.1 - 0.061 11.6 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Rieske PF00355.26 EGG43079.1 - 3.9e-18 65.2 0.0 4.5e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EGG43079.1 - 4.8e-13 48.9 0.0 5.5e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Aminotran_5 PF00266.19 EGG43080.1 - 5.3e-151 502.8 0.7 6.1e-151 502.6 0.7 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGG43080.1 - 5.4e-07 29.1 0.2 4.6e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGG43080.1 - 0.0001 21.0 0.0 0.00025 19.7 0.0 1.6 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGG43080.1 - 0.00015 21.2 0.1 0.00042 19.7 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 EGG43080.1 - 0.039 12.7 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain NifU_N PF01592.16 EGG43081.1 - 1.2e-29 103.0 0.0 1.4e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EGG43081.1 - 0.03 14.5 0.4 0.048 13.9 0.4 1.3 1 0 0 1 1 1 0 TSCPD domain SufE PF02657.15 EGG43081.1 - 0.054 13.3 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Fe-S metabolism associated domain SAM_Ste50p PF09235.10 EGG43081.1 - 0.14 12.4 1.3 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 Ste50p, sterile alpha motif PGK PF00162.19 EGG43083.1 - 6.6e-90 301.8 0.0 7.5e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PAP2 PF01569.21 EGG43084.1 - 3.2e-21 75.5 0.8 5.4e-21 74.8 0.6 1.5 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EGG43084.1 - 6.3e-11 42.3 3.2 1.3e-10 41.2 3.2 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EGG43084.1 - 1.4e-05 25.5 1.7 2.3e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal DUF212 PF02681.14 EGG43084.1 - 0.11 12.6 0.6 0.77 9.9 0.6 2.1 1 1 0 1 1 1 0 Divergent PAP2 family Wzy_C PF04932.15 EGG43084.1 - 0.37 10.4 3.2 5 6.7 0.0 2.2 2 0 0 2 2 2 0 O-Antigen ligase TFIIB PF00382.19 EGG43086.1 - 2.7e-32 110.6 5.1 3.7e-16 58.9 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG43086.1 - 1.1e-07 31.2 0.1 1.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_11 PF08279.12 EGG43086.1 - 0.00022 21.1 2.2 0.14 12.1 0.0 3.3 3 0 0 3 3 3 1 HTH domain Cyclin_C PF02984.19 EGG43086.1 - 0.0034 17.4 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_AsnC-type PF13404.6 EGG43086.1 - 0.0042 16.9 0.1 0.25 11.2 0.1 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Phage_terminase PF10668.9 EGG43086.1 - 0.0075 16.3 0.2 4.1 7.5 0.0 3.3 3 0 0 3 3 3 1 Phage terminase small subunit HTH_23 PF13384.6 EGG43086.1 - 0.0076 16.0 0.2 3.5 7.6 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EGG43086.1 - 0.0089 15.7 2.6 0.9 9.3 0.1 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EGG43086.1 - 0.0095 15.4 0.0 0.48 10.0 0.0 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 Cyclin_N PF00134.23 EGG43086.1 - 0.014 15.1 0.2 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF294_C PF10335.9 EGG43086.1 - 0.021 14.6 0.4 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain RB_B PF01857.20 EGG43086.1 - 0.027 14.5 0.1 0.07 13.2 0.1 1.9 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain MarR PF01047.22 EGG43086.1 - 0.049 13.6 0.1 0.36 10.8 0.0 2.4 3 0 0 3 3 2 0 MarR family TPR_5 PF12688.7 EGG43086.1 - 0.056 13.7 0.2 0.16 12.2 0.1 1.8 1 1 0 1 1 1 0 Tetratrico peptide repeat HTH_24 PF13412.6 EGG43086.1 - 0.065 12.8 0.1 16 5.1 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding zinc_ribbon_2 PF13240.6 EGG43086.1 - 0.082 12.6 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 EGG43086.1 - 1.5 8.6 3.7 9.5 6.0 2.7 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosoarchaeum_limnia_SFB1-ASM20458v1/GCA_000204585.1_ASM20458v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosoarchaeum_limnia_SFB1-ASM20458v1/GCA_000204585.1_ASM20458v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosoarchaeum_limnia_SFB1-ASM20458v1/GCA_000204585.1_ASM20458v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Thaumarchaeota/Candidatus_Nitrosoarchaeum_limnia_SFB1-ASM20458v1/GCA_000204585.1_ASM20458v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 16:18:56 2019 # [ok]